Pyruvate kinase

Overview
NamePyruvate kinase
Smed IDSMED30006660
Length (bp)1716
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Pyruvate kinase (SMED30006660) t-SNE clustered cells

Violin plots show distribution of expression levels for Pyruvate kinase (SMED30006660) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Pyruvate kinase (SMED30006660) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Pyruvate kinase (SMED30006660) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006660

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymal cellSMED30006660h1SMcG0014283 dd_Smed_v4_10576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30006660h1SMcG0014283 dd_Smed_v4_10576_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Pyruvate kinase vs. Ensembl Human
Match: PKM (pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021])

HSP 1 Score: 656.366 bits (1692), Expect = 0.000e+0
Identity = 316/507 (62.33%), Postives = 399/507 (78.70%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++TL  M+ SGMNVARLNFSHGTHEYHAETIK VR A E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  K  +E+   + H  + +EA A+ +VEA+    A+A+IVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P+L + P  + W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. Ensembl Human
Match: PKM (pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021])

HSP 1 Score: 656.366 bits (1692), Expect = 0.000e+0
Identity = 316/507 (62.33%), Postives = 399/507 (78.70%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++TL  M+ SGMNVARLNFSHGTHEYHAETIK VR A E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  K  +E+   + H  + +EA A+ +VEA+    A+A+IVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P+L + P  + W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. Ensembl Human
Match: PKM (pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021])

HSP 1 Score: 656.366 bits (1692), Expect = 0.000e+0
Identity = 316/507 (62.33%), Postives = 399/507 (78.70%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++TL  M+ SGMNVARLNFSHGTHEYHAETIK VR A E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  K  +E+   + H  + +EA A+ +VEA+    A+A+IVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P+L + P  + W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. Ensembl Human
Match: PKM (pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021])

HSP 1 Score: 656.366 bits (1692), Expect = 0.000e+0
Identity = 316/507 (62.33%), Postives = 399/507 (78.70%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++TL  M+ SGMNVARLNFSHGTHEYHAETIK VR A E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  K  +E+   + H  + +EA A+ +VEA+    A+A+IVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P+L + P  + W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. Ensembl Human
Match: PKM (pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021])

HSP 1 Score: 645.58 bits (1664), Expect = 0.000e+0
Identity = 314/507 (61.93%), Postives = 399/507 (78.70%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++TL  M+ SGMNVARLNFSHGTHEYHAETIK VR A E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  +  +  +E++ +    ++  EA+A+ AVEA+    + AIIVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P+L + P  + W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. Ensembl Celegans
Match: pyk-1 (Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL40])

HSP 1 Score: 565.074 bits (1455), Expect = 0.000e+0
Identity = 294/502 (58.57%), Postives = 370/502 (73.71%), Query Frame = 2 
Query:  146 LSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            + HLC  DI   P  VR TGIICTIGPAC S++ L  ++ +GMN+ARLNFSHG+HEYHA TI  VREA ++F   +R I IALDTKGPEIRTGL+ G  +AEI L  G  IR+ TD  F+E     NL++DYKNI  +L +G+++YIDDGLISLIV+    D + C VENGG+LGS+KGVNLPG  VDLPAVSEKD +DL+FGVEQ VDI+FASFIRNA+ IR IR +LGE+GK I IIAKIEN EG+   DEII E+DG+MVARGD+GIEIPA+KV +AQKM+I+KCN+ GKPVICATQMLESMV KPRPTRAE SDVANAVLDG+DCVMLSGE+AKG +P+ A+K MH +CKEAEA  +  +   E+    +   +     AIAA  AA    ASAI+++TTTG S+   S+Y+P  PIL ++R+  V RQ HL+RG+ P+     R  +W  DVD RI+ +I  G   G + KGD +V+VT W+  +G+TNT+RI+  +
Sbjct:   62 MEHLCRLDIREAPHLVRQTGIICTIGPACASVEMLQKLILNGMNIARLNFSHGSHEYHAGTIANVREAADSFS-DKRVIGIALDTKGPEIRTGLLAGGASAEIELARGASIRLTTDPHFSESGTAVNLFVDYKNIAKVLSVGSRVYIDDGLISLIVEELQTDAVICSVENGGMLGSRKGVNLPGTIVDLPAVSEKDCKDLQFGVEQGVDIIFASFIRNAEGIRTIRKVLGEKGKKIKIIAKIENQEGVDNADEIISESDGVMVARGDLGIEIPAEKVFLAQKMLISKCNRAGKPVICATQMLESMVHKPRPTRAEGSDVANAVLDGADCVMLSGETAKGEYPVDALKIMHYICKEAEAAVYHRRLFDELLQNTQKPTDMSHTIAIAATSAAASCHASAILLITTTGRSAIQCSRYKPAVPILTISRDVAVCRQLHLYRGVFPVHYPAERAADWPTDVDNRINHAIAIGKDRGFIHKGDFLVVVTGWRQGAGATNTLRIITAE 562
[Close]
BLAST of Pyruvate kinase vs. Ensembl Celegans
Match: pyk-1 (Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL40])

HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0
Identity = 294/502 (58.57%), Postives = 370/502 (73.71%), Query Frame = 2 
Query:  146 LSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            + HLC  DI   P  VR TGIICTIGPAC S++ L  ++ +GMN+ARLNFSHG+HEYHA TI  VREA ++F   +R I IALDTKGPEIRTGL+ G  +AEI L  G  IR+ TD  F+E     NL++DYKNI  +L +G+++YIDDGLISLIV+    D + C VENGG+LGS+KGVNLPG  VDLPAVSEKD +DL+FGVEQ VDI+FASFIRNA+ IR IR +LGE+GK I IIAKIEN EG+   DEII E+DG+MVARGD+GIEIPA+KV +AQKM+I+KCN+ GKPVICATQMLESMV KPRPTRAE SDVANAVLDG+DCVMLSGE+AKG +P+ A+K MH +CKEAEA  +  +   E+    +   +     AIAA  AA    ASAI+++TTTG S+   S+Y+P  PIL ++R+  V RQ HL+RG+ P+     R  +W  DVD RI+ +I  G   G + KGD +V+VT W+  +G+TNT+RI+  +
Sbjct:   58 MEHLCRLDIREAPHLVRQTGIICTIGPACASVEMLQKLILNGMNIARLNFSHGSHEYHAGTIANVREAADSFS-DKRVIGIALDTKGPEIRTGLLAGGASAEIELARGASIRLTTDPHFSESGTAVNLFVDYKNIAKVLSVGSRVYIDDGLISLIVEELQTDAVICSVENGGMLGSRKGVNLPGTIVDLPAVSEKDCKDLQFGVEQGVDIIFASFIRNAEGIRTIRKVLGEKGKKIKIIAKIENQEGVDNADEIISESDGVMVARGDLGIEIPAEKVFLAQKMLISKCNRAGKPVICATQMLESMVHKPRPTRAEGSDVANAVLDGADCVMLSGETAKGEYPVDALKIMHYICKEAEAAVYHRRLFDELLQNTQKPTDMSHTIAIAATSAAASCHASAILLITTTGRSAIQCSRYKPAVPILTISRDVAVCRQLHLYRGVFPVHYPAERAADWPTDVDNRINHAIAIGKDRGFIHKGDFLVVVTGWRQGAGATNTLRIITAE 558
[Close]
BLAST of Pyruvate kinase vs. Ensembl Celegans
Match: pyk-1 (Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL40])

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 294/502 (58.57%), Postives = 370/502 (73.71%), Query Frame = 2 
Query:  146 LSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            + HLC  DI   P  VR TGIICTIGPAC S++ L  ++ +GMN+ARLNFSHG+HEYHA TI  VREA ++F   +R I IALDTKGPEIRTGL+ G  +AEI L  G  IR+ TD  F+E     NL++DYKNI  +L +G+++YIDDGLISLIV+    D + C VENGG+LGS+KGVNLPG  VDLPAVSEKD +DL+FGVEQ VDI+FASFIRNA+ IR IR +LGE+GK I IIAKIEN EG+   DEII E+DG+MVARGD+GIEIPA+KV +AQKM+I+KCN+ GKPVICATQMLESMV KPRPTRAE SDVANAVLDG+DCVMLSGE+AKG +P+ A+K MH +CKEAEA  +  +   E+    +   +     AIAA  AA    ASAI+++TTTG S+   S+Y+P  PIL ++R+  V RQ HL+RG+ P+     R  +W  DVD RI+ +I  G   G + KGD +V+VT W+  +G+TNT+RI+  +
Sbjct:   31 MEHLCRLDIREAPHLVRQTGIICTIGPACASVEMLQKLILNGMNIARLNFSHGSHEYHAGTIANVREAADSFS-DKRVIGIALDTKGPEIRTGLLAGGASAEIELARGASIRLTTDPHFSESGTAVNLFVDYKNIAKVLSVGSRVYIDDGLISLIVEELQTDAVICSVENGGMLGSRKGVNLPGTIVDLPAVSEKDCKDLQFGVEQGVDIIFASFIRNAEGIRTIRKVLGEKGKKIKIIAKIENQEGVDNADEIISESDGVMVARGDLGIEIPAEKVFLAQKMLISKCNRAGKPVICATQMLESMVHKPRPTRAEGSDVANAVLDGADCVMLSGETAKGEYPVDALKIMHYICKEAEAAVYHRRLFDELLQNTQKPTDMSHTIAIAATSAAASCHASAILLITTTGRSAIQCSRYKPAVPILTISRDVAVCRQLHLYRGVFPVHYPAERAADWPTDVDNRINHAIAIGKDRGFIHKGDFLVVVTGWRQGAGATNTLRIITAE 531
[Close]
BLAST of Pyruvate kinase vs. Ensembl Celegans
Match: pyk-1 (Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL40])

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 294/502 (58.57%), Postives = 370/502 (73.71%), Query Frame = 2 
Query:  146 LSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            + HLC  DI   P  VR TGIICTIGPAC S++ L  ++ +GMN+ARLNFSHG+HEYHA TI  VREA ++F   +R I IALDTKGPEIRTGL+ G  +AEI L  G  IR+ TD  F+E     NL++DYKNI  +L +G+++YIDDGLISLIV+    D + C VENGG+LGS+KGVNLPG  VDLPAVSEKD +DL+FGVEQ VDI+FASFIRNA+ IR IR +LGE+GK I IIAKIEN EG+   DEII E+DG+MVARGD+GIEIPA+KV +AQKM+I+KCN+ GKPVICATQMLESMV KPRPTRAE SDVANAVLDG+DCVMLSGE+AKG +P+ A+K MH +CKEAEA  +  +   E+    +   +     AIAA  AA    ASAI+++TTTG S+   S+Y+P  PIL ++R+  V RQ HL+RG+ P+     R  +W  DVD RI+ +I  G   G + KGD +V+VT W+  +G+TNT+RI+  +
Sbjct:   31 MEHLCRLDIREAPHLVRQTGIICTIGPACASVEMLQKLILNGMNIARLNFSHGSHEYHAGTIANVREAADSFS-DKRVIGIALDTKGPEIRTGLLAGGASAEIELARGASIRLTTDPHFSESGTAVNLFVDYKNIAKVLSVGSRVYIDDGLISLIVEELQTDAVICSVENGGMLGSRKGVNLPGTIVDLPAVSEKDCKDLQFGVEQGVDIIFASFIRNAEGIRTIRKVLGEKGKKIKIIAKIENQEGVDNADEIISESDGVMVARGDLGIEIPAEKVFLAQKMLISKCNRAGKPVICATQMLESMVHKPRPTRAEGSDVANAVLDGADCVMLSGETAKGEYPVDALKIMHYICKEAEAAVYHRRLFDELLQNTQKPTDMSHTIAIAATSAAASCHASAILLITTTGRSAIQCSRYKPAVPILTISRDVAVCRQLHLYRGVFPVHYPAERAADWPTDVDNRINHAIAIGKDRGFIHKGDFLVVVTGWRQGAGATNTLRIITAE 531
[Close]
BLAST of Pyruvate kinase vs. Ensembl Celegans
Match: pyk-1 (Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL40])

HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0
Identity = 294/502 (58.57%), Postives = 370/502 (73.71%), Query Frame = 2 
Query:  146 LSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            + HLC  DI   P  VR TGIICTIGPAC S++ L  ++ +GMN+ARLNFSHG+HEYHA TI  VREA ++F   +R I IALDTKGPEIRTGL+ G  +AEI L  G  IR+ TD  F+E     NL++DYKNI  +L +G+++YIDDGLISLIV+    D + C VENGG+LGS+KGVNLPG  VDLPAVSEKD +DL+FGVEQ VDI+FASFIRNA+ IR IR +LGE+GK I IIAKIEN EG+   DEII E+DG+MVARGD+GIEIPA+KV +AQKM+I+KCN+ GKPVICATQMLESMV KPRPTRAE SDVANAVLDG+DCVMLSGE+AKG +P+ A+K MH +CKEAEA  +  +   E+    +   +     AIAA  AA    ASAI+++TTTG S+   S+Y+P  PIL ++R+  V RQ HL+RG+ P+     R  +W  DVD RI+ +I  G   G + KGD +V+VT W+  +G+TNT+RI+  +
Sbjct:  100 MEHLCRLDIREAPHLVRQTGIICTIGPACASVEMLQKLILNGMNIARLNFSHGSHEYHAGTIANVREAADSFS-DKRVIGIALDTKGPEIRTGLLAGGASAEIELARGASIRLTTDPHFSESGTAVNLFVDYKNIAKVLSVGSRVYIDDGLISLIVEELQTDAVICSVENGGMLGSRKGVNLPGTIVDLPAVSEKDCKDLQFGVEQGVDIIFASFIRNAEGIRTIRKVLGEKGKKIKIIAKIENQEGVDNADEIISESDGVMVARGDLGIEIPAEKVFLAQKMLISKCNRAGKPVICATQMLESMVHKPRPTRAEGSDVANAVLDGADCVMLSGETAKGEYPVDALKIMHYICKEAEAAVYHRRLFDELLQNTQKPTDMSHTIAIAATSAAASCHASAILLITTTGRSAIQCSRYKPAVPILTISRDVAVCRQLHLYRGVFPVHYPAERAADWPTDVDNRINHAIAIGKDRGFIHKGDFLVVVTGWRQGAGATNTLRIITAE 600
[Close]
BLAST of Pyruvate kinase vs. Ensembl Fly
Match: PyK (gene:FBgn0267385 transcript:FBtr0084213)

HSP 1 Score: 615.15 bits (1585), Expect = 0.000e+0
Identity = 305/513 (59.45%), Postives = 385/513 (75.05%), Query Frame = 2 
Query:  122 MKNKPDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            M    D  L H+C    DS    VR +GI+CTIGPA  S++ L  MM++GMN+AR+NFSHG+HEYHA T+  VR+A++ +     +  P+AIALDTKGPEIRTGLI GSGTAEI L  G++I++ T+  F EK   + +++DY+NI N++  GN++++DDGLISLIV+  GKD L C+VENGG LGS+KGVNLPG  VDLPAVSEKDK DL FGVEQ VD++FASFIRNA A+ EIR +LGE+GK+I II+KIEN +G+  +DEIIE  DGIMVARGD+GIEIPA+KV +AQK MIA+CNK GKPVICATQMLESMV KPRPTRAEISDVANAVLDG+DCVMLSGE+AKG +P++ V TM + CKEAEA  +      ++       +    A+  A   A + +KASAI+V+TT+G S+  +SKYRPRCPI+AVTR    ARQ HL+RGL PL+ + P L +W +DVD R+   +Q G K+G +K GDSVV+VT WK  SG TNTIRIV V+
Sbjct:    1 MAAGADTQLEHMCRLQFDSPVPHVRLSGIVCTIGPASSSVEMLEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIALDTKGPEIRTGLIGGSGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFVDDGLISLIVREVGKDSLTCEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLLFGVEQEVDMIFASFIRNAAALTEIRKVLGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHQNLFNDLVRGAGTIDASHAAAIAAVEAATK-AKASAIVVITTSGKSAFQVSKYRPRCPIIAVTRFAQTARQAHLYRGLVPLIYKEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGFTNTIRIVTVE 512
[Close]
BLAST of Pyruvate kinase vs. Ensembl Fly
Match: PyK (gene:FBgn0267385 transcript:FBtr0084214)

HSP 1 Score: 614.379 bits (1583), Expect = 0.000e+0
Identity = 305/513 (59.45%), Postives = 385/513 (75.05%), Query Frame = 2 
Query:  122 MKNKPDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            M    D  L H+C    DS    VR +GI+CTIGPA  S++ L  MM++GMN+AR+NFSHG+HEYHA T+  VR+A++ +     +  P+AIALDTKGPEIRTGLI GSGTAEI L  G++I++ T+  F EK   + +++DY+NI N++  GN++++DDGLISLIV+  GKD L C+VENGG LGS+KGVNLPG  VDLPAVSEKDK DL FGVEQ VD++FASFIRNA A+ EIR +LGE+GK+I II+KIEN +G+  +DEIIE  DGIMVARGD+GIEIPA+KV +AQK MIA+CNK GKPVICATQMLESMV KPRPTRAEISDVANAVLDG+DCVMLSGE+AKG +P++ V TM + CKEAEA  +      ++       +    A+  A   A + +KASAI+V+TT+G S+  +SKYRPRCPI+AVTR    ARQ HL+RGL PL+ + P L +W +DVD R+   +Q G K+G +K GDSVV+VT WK  SG TNTIRIV V+
Sbjct:   22 MAAGADTQLEHMCRLQFDSPVPHVRLSGIVCTIGPASSSVEMLEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIALDTKGPEIRTGLIGGSGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFVDDGLISLIVREVGKDSLTCEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLLFGVEQEVDMIFASFIRNAAALTEIRKVLGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHQNLFNDLVRGAGTIDASHAAAIAAVEAATK-AKASAIVVITTSGKSAFQVSKYRPRCPIIAVTRFAQTARQAHLYRGLVPLIYKEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGFTNTIRIVTVE 533
[Close]
BLAST of Pyruvate kinase vs. Ensembl Fly
Match: CG7069 (gene:FBgn0038952 transcript:FBtr0084215)

HSP 1 Score: 433.335 bits (1113), Expect = 1.342e-143
Identity = 220/412 (53.40%), Postives = 296/412 (71.84%), Query Frame = 2 
Query:  272 MNVARLNFSHGTHEYHAETIKLVREAIETFKPHR---RPIAIALDTKGPEIRTG-LIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFF----QNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVE 1483
            M V R+NFSHG+HEYH +TI+  R+AI  +       R +AIALDTKGPEIRTG L  G+  AEI L  G ++ + T    A+K ++ N+++DY+ +  ++  GN++++DDGLI+LIV+    D + C+VENGG LGS KG+NLPG  VDLP+V+EKDKQDLKFG EQ VD++FASFIR+A+A++EIR +LG  G  I II+KIENH+G+  ID+II E+DGIMVARGDMGIEIP + V +AQK ++AKCNK GKPVICATQM+ESM +KPRPTRAE SDVANA+ DG D VMLSGE+AKG +P++ V+ M  +C + EA+ +    QN   +EI+       +H+ A   A  EAA + +A AI+V +     + ++S  RP CPI+ +T NE  A Q  L+RG++PLLVE
Sbjct:    1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGNDRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKESKGDEVICQVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLGPAGACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVICATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECVQCMARICAKVEAVLWYESLQNSLKREIRT---SAADHISAVTTAIAEAATVGQARAIVVASPCSMVAQMVSHMRPPCPIVMLTGNESEAAQSLLFRGIYPLLVE 409
[Close]
BLAST of Pyruvate kinase vs. Ensembl Fly
Match: CG2964 (gene:FBgn0031462 transcript:FBtr0077722)

HSP 1 Score: 413.305 bits (1061), Expect = 2.854e-138
Identity = 213/502 (42.43%), Postives = 330/502 (65.74%), Query Frame = 2 
Query:  146 LSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHR---RPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIV 1642
            LSH+C+ D+       R   +I TI  + ++  T++ M+  G+N+ RLNFSH +HE H++TI+L+ EA+E         R +AIA DT+GP+IRTGL+ G    ++ L  G  +R+  +    +K +++ +++DY NI N+   G++++IDDG + L +   G D L C+V +GG L +   V LP  ++DLPAVSEKD  D++F ++ NVD +FAS +R+A  ++E+R++LGE+GKHI IIAK+++   + R  EI+  ADG++++R D+G +IP +K+ + QK ++ +CNK GKPVI A+ +LESM + P PTRAE  D+ANA++DG+DC+MLS E A GSFP + V T   +C+EAE + +      ++ +  R   +   + AIAAVE A+ + A+ IIVLTT+G S+ L+SK+RPRCPI+A+TR E  AR  +L RG+ P+L       +++ DVDAR+  ++    K GI+  GD +VIV+ WK   G TN +R+V
Sbjct:   16 LSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRSGDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCEVIHGGQLNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAIAAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEPSTDYATDVDARVQFAMTSAKKWGIIDDGDPIVIVSAWKDGGGFTNNVRVV 513
[Close]
BLAST of Pyruvate kinase vs. Ensembl Fly
Match: CG7362 (gene:FBgn0038258 transcript:FBtr0331700)

HSP 1 Score: 249.595 bits (636), Expect = 3.949e-73
Identity = 133/270 (49.26%), Postives = 188/270 (69.63%), Query Frame = 2 
Query:  683 VNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILG--EEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNR-HFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVE 1483
            +N  G   DL A++E+DK DLKFG +Q VD++FASFIR+A A++EIR  LG     +HI II+KIE+ + +  IDEII E+DGIMVA G+MG EI  + V +AQK ++AKCNK GKPVICA QM+ SM++KPRPTRAE SDVANA+LDG D ++LS E+AKG +P+Q V+ M  +C + E++ +       +K+  R +  +H+ A + A  EAA +S+A AI+V +     S ++S+ RP CPI+ +T     A Q  L+RG++PLLV+
Sbjct:  109 INPQGVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACPSSEHIKIISKIESQQALANIDEIIRESDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVICANQMMNSMITKPRPTRAESSDVANAILDGCDALVLSDETAKGKYPVQCVQCMARICAKVESVLWYESIQNNLKSEVRINAADHISAVSTAIAEAATVSQAQAIVVASPCSIVSQMVSQMRPPCPIVLLTGCPHEAAQSLLFRGVYPLLVK 378

HSP 2 Score: 70.4774 bits (171), Expect = 2.564e-12
Identity = 35/75 (46.67%), Postives = 47/75 (62.67%), Query Frame = 2 
Query:  200 TGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHR---RPIAIALDTKGPEI 415
            T IICTIGP+    + L  ++ +GM V RL+FS GTH+ H + I+  R+AI  +       R +AIALDTKGP I
Sbjct:   35 TSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCHCQAIQAARKAIAMYAEETGLPRSLAIALDTKGPVI 109
[Close]
BLAST of Pyruvate kinase vs. Ensembl Zebrafish
Match: pkma (pyruvate kinase M1/2a [Source:ZFIN;Acc:ZDB-GENE-031201-4])

HSP 1 Score: 647.892 bits (1670), Expect = 0.000e+0
Identity = 311/507 (61.34%), Postives = 392/507 (77.32%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P   RNTGIICTIGPA +S+ TL  M+ SGMN+AR+NFSHG+HEYH ETIK VREA  +F+P     RP+ IALDTKGPEIRTGLI+GSGTAE+ L  G +I++  DD F E CDE  LWLDYKNIT ++++G+K+YIDDGLISL V   G DYL C++ENGG LGSKKGVNLPGA VDLPAVSEKD +DL+FGVE  VD++FASFIR A  ++ +R +LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CNK GKP+ICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  + ++  +    +  +A A+ AVEA+    AS II+LT TG S+HLIS+YRPR PILAVTRNE  ARQ HL+RG+ P+    P  D W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   25 DTFLEHMCLLDIDSEPTIARNTGIICTIGPASRSVDTLKEMIKSGMNIARMNFSHGSHEYHGETIKNVREACASFEPGSIQYRPVGIALDTKGPEIRTGLIKGSGTAEVELKKGNKIKVTLDDSFMENCDEDTLWLDYKNITKVVEVGSKVYIDDGLISLQVLQIGSDYLICEIENGGSLGSKKGVNLPGAAVDLPAVSEKDIKDLQFGVEMGVDMIFASFIRKAADVQAVRKVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNKAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAATFHRQLFEGLRRSSVLTRDPSDAVAVGAVEASFKCCASGIIILTKTGRSAHLISRYRPRAPILAVTRNEQTARQAHLYRGIFPIYYNSPSNDVWAEDVDLRVNFAMDVGKARGFFKAGDVVIVLTGWRPGSGYTNTMRVVPV 531
[Close]
BLAST of Pyruvate kinase vs. Ensembl Zebrafish
Match: pkma (pyruvate kinase M1/2a [Source:ZFIN;Acc:ZDB-GENE-031201-4])

HSP 1 Score: 647.892 bits (1670), Expect = 0.000e+0
Identity = 311/507 (61.34%), Postives = 392/507 (77.32%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P   RNTGIICTIGPA +S+ TL  M+ SGMN+AR+NFSHG+HEYH ETIK VREA  +F+P     RP+ IALDTKGPEIRTGLI+GSGTAE+ L  G +I++  DD F E CDE  LWLDYKNIT ++++G+K+YIDDGLISL V   G DYL C++ENGG LGSKKGVNLPGA VDLPAVSEKD +DL+FGVE  VD++FASFIR A  ++ +R +LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CNK GKP+ICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  + ++  +    +  +A A+ AVEA+    AS II+LT TG S+HLIS+YRPR PILAVTRNE  ARQ HL+RG+ P+    P  D W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   25 DTFLEHMCLLDIDSEPTIARNTGIICTIGPASRSVDTLKEMIKSGMNIARMNFSHGSHEYHGETIKNVREACASFEPGSIQYRPVGIALDTKGPEIRTGLIKGSGTAEVELKKGNKIKVTLDDSFMENCDEDTLWLDYKNITKVVEVGSKVYIDDGLISLQVLQIGSDYLICEIENGGSLGSKKGVNLPGAAVDLPAVSEKDIKDLQFGVEMGVDMIFASFIRKAADVQAVRKVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNKAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAATFHRQLFEGLRRSSVLTRDPSDAVAVGAVEASFKCCASGIIILTKTGRSAHLISRYRPRAPILAVTRNEQTARQAHLYRGIFPIYYNSPSNDVWAEDVDLRVNFAMDVGKARGFFKAGDVVIVLTGWRPGSGYTNTMRVVPV 531
[Close]
BLAST of Pyruvate kinase vs. Ensembl Zebrafish
Match: pkma (pyruvate kinase M1/2a [Source:ZFIN;Acc:ZDB-GENE-031201-4])

HSP 1 Score: 646.351 bits (1666), Expect = 0.000e+0
Identity = 312/507 (61.54%), Postives = 392/507 (77.32%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P   RNTGIICTIGPA +S+ TL  M+ SGMN+AR+NFSHG+HEYH ETIK VREA  +F+P     RP+ IALDTKGPEIRTGLI+GSGTAE+ L  G +I++  DD F E CDE  LWLDYKNIT ++++G+K+YIDDGLISL V   G DYL C++ENGG LGSKKGVNLPGA VDLPAVSEKD +DL+FGVE  VD++FASFIR A  ++ +R +LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CNK GKP+ICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  ++++       +  EA AI AVEA+    +SA IVLT +G S+HLIS+YRPR PILAVTRNE  ARQ HL+RG+ P+    P  D W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   25 DTFLEHMCLLDIDSEPTIARNTGIICTIGPASRSVDTLKEMIKSGMNIARMNFSHGSHEYHGETIKNVREACASFEPGSIQYRPVGIALDTKGPEIRTGLIKGSGTAEVELKKGNKIKVTLDDSFMENCDEDTLWLDYKNITKVVEVGSKVYIDDGLISLQVLQIGSDYLICEIENGGSLGSKKGVNLPGAAVDLPAVSEKDIKDLQFGVEMGVDMIFASFIRKAADVQAVRKVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNKAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQVFEDLRRCLPLSTDPAEAIAIGAVEASFKILSSAFIVLTGSGRSAHLISRYRPRAPILAVTRNEQTARQAHLYRGIFPIYYNSPSNDVWAEDVDLRVNFAMDVGKARGFFKAGDVVIVLTGWRPGSGYTNTMRVVPV 531
[Close]
BLAST of Pyruvate kinase vs. Ensembl Zebrafish
Match: pkmb (pyruvate kinase M1/2b [Source:ZFIN;Acc:ZDB-GENE-040801-230])

HSP 1 Score: 637.106 bits (1642), Expect = 0.000e+0
Identity = 310/507 (61.14%), Postives = 392/507 (77.32%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            +  L HLC  DIDS+P   RNTGI+CT+GPA +S++TL  M+ SGMNVARLNFSHGTHEYHAETIK VREAIE+F       RP+AIALDTKGPEIRTGLI+GSGT E+ LV G  I++  DD F + CDE  LWLDYKNIT ++  G+ IY+DDGLISL V+  G D+L+C++ENGG+LGSKKGVNLPGA VDLPAVSEKD +DL+FGVEQ VD+VFASFIR A  +  +R +LGE+GK I II+K+ENHEG+++ DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI++CN+ GKP+ICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +PI++V T H + +EAEA  F  +  +E++  +    +  E+ A+ AVEA+    ASAII LT TG S+ L+S+YRPR PI+AVTRN   +RQ HL+RG+ P+L   P  D W+EDVD R+  +++ G      K GD +++VT W+P SG TNT+RIV V
Sbjct:   23 ETFLEHLCLLDIDSEPTVSRNTGIVCTLGPASRSLETLREMILSGMNVARLNFSHGTHEYHAETIKSVREAIESFGAGTIDYRPVAIALDTKGPEIRTGLIKGSGTEEVKLVKGNIIKLTLDDKFMDNCDENTLWLDYKNITKVVQQGSHIYVDDGLISLKVKEIGSDFLNCEIENGGMLGSKKGVNLPGANVDLPAVSEKDIKDLQFGVEQGVDMVFASFIRKAADVHAVRKVLGEKGKDIRIISKLENHEGVRKFDEILEASDGIMVARGDLGIEIPTEKVFLAQKMMISRCNRIGKPIICATQMLESMIKKPRPTRAESSDVANAVLDGADCIMLSGETAKGEYPIESVLTQHLIAREAEAAMFHRQLFEELRRTSHLTRDPTESVAVGAVEASFKCCASAIICLTKTGRSAQLLSRYRPRAPIMAVTRNGQTSRQLHLYRGVIPILYTKPANDIWAEDVDLRVSFALEIGKHRKYFKSGDVIIVVTGWRPGSGYTNTMRIVVV 529
[Close]
BLAST of Pyruvate kinase vs. Ensembl Zebrafish
Match: pkmb (pyruvate kinase M1/2b [Source:ZFIN;Acc:ZDB-GENE-040801-230])

HSP 1 Score: 637.106 bits (1642), Expect = 0.000e+0
Identity = 310/507 (61.14%), Postives = 392/507 (77.32%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            +  L HLC  DIDS+P   RNTGI+CT+GPA +S++TL  M+ SGMNVARLNFSHGTHEYHAETIK VREAIE+F       RP+AIALDTKGPEIRTGLI+GSGT E+ LV G  I++  DD F + CDE  LWLDYKNIT ++  G+ IY+DDGLISL V+  G D+L+C++ENGG+LGSKKGVNLPGA VDLPAVSEKD +DL+FGVEQ VD+VFASFIR A  +  +R +LGE+GK I II+K+ENHEG+++ DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI++CN+ GKP+ICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +PI++V T H + +EAEA  F  +  +E++  +    +  E+ A+ AVEA+    ASAII LT TG S+ L+S+YRPR PI+AVTRN   +RQ HL+RG+ P+L   P  D W+EDVD R+  +++ G      K GD +++VT W+P SG TNT+RIV V
Sbjct:   23 ETFLEHLCLLDIDSEPTVSRNTGIVCTLGPASRSLETLREMILSGMNVARLNFSHGTHEYHAETIKSVREAIESFGAGTIDYRPVAIALDTKGPEIRTGLIKGSGTEEVKLVKGNIIKLTLDDKFMDNCDENTLWLDYKNITKVVQQGSHIYVDDGLISLKVKEIGSDFLNCEIENGGMLGSKKGVNLPGANVDLPAVSEKDIKDLQFGVEQGVDMVFASFIRKAADVHAVRKVLGEKGKDIRIISKLENHEGVRKFDEILEASDGIMVARGDLGIEIPTEKVFLAQKMMISRCNRIGKPIICATQMLESMIKKPRPTRAESSDVANAVLDGADCIMLSGETAKGEYPIESVLTQHLIAREAEAAMFHRQLFEELRRTSHLTRDPTESVAVGAVEASFKCCASAIICLTKTGRSAQLLSRYRPRAPIMAVTRNGQTSRQLHLYRGVIPILYTKPANDIWAEDVDLRVSFALEIGKHRKYFKSGDVIIVVTGWRPGSGYTNTMRIVVV 529
[Close]
BLAST of Pyruvate kinase vs. Ensembl Xenopus
Match: pkm (pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224])

HSP 1 Score: 635.18 bits (1637), Expect = 0.000e+0
Identity = 312/507 (61.54%), Postives = 394/507 (77.71%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P   RNTGIICTIGPA +S++ L  M+ SGMN+ARLNFSHGTHEYHA TIK VREA E+F     H RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  +RI  DD F EKCDE  LW+DYKN+T ++  G+KIY+DDGLISL+V+  G D+   +VENGG+LGSKKGVNLPGA VDLPAVS KD QDL+FGVEQNVD+VFASFIR A  +  +R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  +  +E++ V+    +  EA+A+ AVE++    + AIIVLT +G S+HL+S+YRPR PI+AVTRN   ARQ HL+RG+ P+L      + W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   21 DTFLEHMCRLDIDSEPIVARNTGIICTIGPASRSVEILKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESFSSNPIHYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLRITLDDAFQEKCDENILWVDYKNLTKVVKPGSKIYVDDGLISLLVKETGADFCLTEVENGGMLGSKKGVNLPGAAVDLPAVSTKDIQDLQFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAIFHRQLFEELRRVSPLTRDPTEATAVGAVESSFKCSSGAIIVLTKSGRSAHLVSRYRPRAPIIAVTRNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDMRVNFAMDIGKARGFFKSGDVVIVLTGWRPGSGFTNTMRVVPV 527
[Close]
BLAST of Pyruvate kinase vs. Ensembl Xenopus
Match: pkm (pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224])

HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 312/507 (61.54%), Postives = 394/507 (77.71%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P   RNTGIICTIGPA +S++ L  M+ SGMN+ARLNFSHGTHEYHA TIK VREA E+F     H RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  +RI  DD F EKCDE  LW+DYKN+T ++  G+KIY+DDGLISL+V+  G D+   +VENGG+LGSKKGVNLPGA VDLPAVS KD QDL+FGVEQNVD+VFASFIR A  +  +R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  +  +E++ V+    +  EA+A+ AVE++    + AIIVLT +G S+HL+S+YRPR PI+AVTRN   ARQ HL+RG+ P+L      + W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   21 DTFLEHMCRLDIDSEPIVARNTGIICTIGPASRSVEILKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESFSSNPIHYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLRITLDDAFQEKCDENILWVDYKNLTKVVKPGSKIYVDDGLISLLVKETGADFCLTEVENGGMLGSKKGVNLPGAAVDLPAVSTKDIQDLQFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAIFHRQLFEELRRVSPLTRDPTEATAVGAVESSFKCSSGAIIVLTKSGRSAHLVSRYRPRAPIIAVTRNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDMRVNFAMDIGKARGFFKSGDVVIVLTGWRPGSGFTNTMRVVPV 527
[Close]
BLAST of Pyruvate kinase vs. Ensembl Xenopus
Match: pkm (pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224])

HSP 1 Score: 634.41 bits (1635), Expect = 0.000e+0
Identity = 312/507 (61.54%), Postives = 394/507 (77.71%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P   RNTGIICTIGPA +S++ L  M+ SGMN+ARLNFSHGTHEYHA TIK VREA E+F     H RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  +RI  DD F EKCDE  LW+DYKN+T ++  G+KIY+DDGLISL+V+  G D+   +VENGG+LGSKKGVNLPGA VDLPAVS KD QDL+FGVEQNVD+VFASFIR A  +  +R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  +  +E++ V+    +  EA+A+ AVE++    + AIIVLT +G S+HL+S+YRPR PI+AVTRN   ARQ HL+RG+ P+L      + W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   23 DTFLEHMCRLDIDSEPIVARNTGIICTIGPASRSVEILKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESFSSNPIHYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLRITLDDAFQEKCDENILWVDYKNLTKVVKPGSKIYVDDGLISLLVKETGADFCLTEVENGGMLGSKKGVNLPGAAVDLPAVSTKDIQDLQFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAIFHRQLFEELRRVSPLTRDPTEATAVGAVESSFKCSSGAIIVLTKSGRSAHLVSRYRPRAPIIAVTRNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDMRVNFAMDIGKARGFFKSGDVVIVLTGWRPGSGFTNTMRVVPV 529
[Close]
BLAST of Pyruvate kinase vs. Ensembl Xenopus
Match: pkm (pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224])

HSP 1 Score: 634.024 bits (1634), Expect = 0.000e+0
Identity = 312/507 (61.54%), Postives = 390/507 (76.92%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P   RNTGIICTIGPA +S++ L  M+ SGMN+ARLNFSHGTHEYHA TIK VREA E+F     H RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  +RI  DD F EKCDE  LW+DYKN+T ++  G+KIY+DDGLISL+V+  G D+   +VENGG+LGSKKGVNLPGA VDLPAVS KD QDL+FGVEQNVD+VFASFIR A  +  +R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H +  EAEA  F  +  +E+        +  EA A+ AVEA+    ASA+IV+T +G S+HL+S+YRPR PI+AVTRN   ARQ HL+RG+ P+L      + W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   20 DTFLEHMCRLDIDSEPIVARNTGIICTIGPASRSVEILKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESFSSNPIHYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLRITLDDAFQEKCDENILWVDYKNLTKVVKPGSKIYVDDGLISLLVKETGADFCLTEVENGGMLGSKKGVNLPGAAVDLPAVSTKDIQDLQFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIALEAEAAAFHRQLFEELFRATASSKDPAEAMALGAVEASFKCLASALIVMTESGRSAHLVSRYRPRAPIIAVTRNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDMRVNFAMDIGKARGFFKSGDVVIVLTGWRPGSGFTNTMRVVPV 526
[Close]
BLAST of Pyruvate kinase vs. Ensembl Xenopus
Match: pkm (pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224])

HSP 1 Score: 633.639 bits (1633), Expect = 0.000e+0
Identity = 312/507 (61.54%), Postives = 390/507 (76.92%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P   RNTGIICTIGPA +S++ L  M+ SGMN+ARLNFSHGTHEYHA TIK VREA E+F     H RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  +RI  DD F EKCDE  LW+DYKN+T ++  G+KIY+DDGLISL+V+  G D+   +VENGG+LGSKKGVNLPGA VDLPAVS KD QDL+FGVEQNVD+VFASFIR A  +  +R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H +  EAEA  F  +  +E+        +  EA A+ AVEA+    ASA+IV+T +G S+HL+S+YRPR PI+AVTRN   ARQ HL+RG+ P+L      + W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   25 DTFLEHMCRLDIDSEPIVARNTGIICTIGPASRSVEILKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESFSSNPIHYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLRITLDDAFQEKCDENILWVDYKNLTKVVKPGSKIYVDDGLISLLVKETGADFCLTEVENGGMLGSKKGVNLPGAAVDLPAVSTKDIQDLQFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIALEAEAAAFHRQLFEELFRATASSKDPAEAMALGAVEASFKCLASALIVMTESGRSAHLVSRYRPRAPIIAVTRNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDMRVNFAMDIGKARGFFKSGDVVIVLTGWRPGSGFTNTMRVVPV 531
[Close]
BLAST of Pyruvate kinase vs. Ensembl Mouse
Match: Pkm (pyruvate kinase, muscle [Source:MGI Symbol;Acc:MGI:97591])

HSP 1 Score: 652.129 bits (1681), Expect = 0.000e+0
Identity = 315/507 (62.13%), Postives = 398/507 (78.50%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++ L  M+ SGMNVARLNFSHGTHEYHAETIK VREA E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F     +E+   + H  + +EA A+ +VEA+    A+A+IVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P+L +   L+ W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRLLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLNAWAEDVDLRVNLAMDVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. Ensembl Mouse
Match: Pkm (pyruvate kinase, muscle [Source:MGI Symbol;Acc:MGI:97591])

HSP 1 Score: 642.884 bits (1657), Expect = 0.000e+0
Identity = 314/507 (61.93%), Postives = 399/507 (78.70%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++ L  M+ SGMNVARLNFSHGTHEYHAETIK VREA E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  +  +  +E++ +    ++  EA+A+ AVEA+    + AIIVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P+L +   L+ W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLNAWAEDVDLRVNLAMDVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. Ensembl Mouse
Match: Pklr (pyruvate kinase liver and red blood cell [Source:MGI Symbol;Acc:MGI:97604])

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 282/507 (55.62%), Postives = 373/507 (73.57%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L HLC  DIDS+P + R+T II TIGPA +S+  L  M+ +GMN+ARLNFSHG+HEYHAE+I  +REA E+F       RP+AIALDTKGPEIRTG+++G   +E+ +V G Q+ +  D  F  + D K +W+DY NIT ++ +G +IYIDDGLISL+V+  G + L  +VE+GG LG++KGVNLP A+VDLP +SE+D  DL+FGVE NVDI+FASF+R A  +  +R  LG EG+ I II+KIENHEG+K+ DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN  GKPV+CATQMLESM++K RPTRAE SDVANAVLDG+DC+MLSGE+AKGSFP++AVK  H + +EAEA  +  +  +E++       +  E +AI AVEA+    A+AIIVLT TG S+ L+S+YRPR  ++AVTR+   ARQ HL RG+ PLL   P    W++DVD R+   I+ G   G L+ GD V++VT W+P SG TN +R++ +
Sbjct:   36 DTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAAESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFRTRGDAKTVWVDYHNITQVVAVGGRIYIDDGLISLVVRKIGPEGLVTEVEHGGFLGNRKGVNLPNAEVDLPGLSEQDLLDLRFGVEHNVDIIFASFVRKASDVVAVRDALGPEGRGIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAVWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLTI 542
[Close]
BLAST of Pyruvate kinase vs. Ensembl Mouse
Match: Pklr (pyruvate kinase liver and red blood cell [Source:MGI Symbol;Acc:MGI:97604])

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 282/507 (55.62%), Postives = 373/507 (73.57%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L HLC  DIDS+P + R+T II TIGPA +S+  L  M+ +GMN+ARLNFSHG+HEYHAE+I  +REA E+F       RP+AIALDTKGPEIRTG+++G   +E+ +V G Q+ +  D  F  + D K +W+DY NIT ++ +G +IYIDDGLISL+V+  G + L  +VE+GG LG++KGVNLP A+VDLP +SE+D  DL+FGVE NVDI+FASF+R A  +  +R  LG EG+ I II+KIENHEG+K+ DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN  GKPV+CATQMLESM++K RPTRAE SDVANAVLDG+DC+MLSGE+AKGSFP++AVK  H + +EAEA  +  +  +E++       +  E +AI AVEA+    A+AIIVLT TG S+ L+S+YRPR  ++AVTR+   ARQ HL RG+ PLL   P    W++DVD R+   I+ G   G L+ GD V++VT W+P SG TN +R++ +
Sbjct:   67 DTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAAESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFRTRGDAKTVWVDYHNITQVVAVGGRIYIDDGLISLVVRKIGPEGLVTEVEHGGFLGNRKGVNLPNAEVDLPGLSEQDLLDLRFGVEHNVDIIFASFVRKASDVVAVRDALGPEGRGIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPEAVWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLTI 573
[Close]
BLAST of Pyruvate kinase vs. Ensembl Mouse
Match: Pkm (pyruvate kinase, muscle [Source:MGI Symbol;Acc:MGI:97591])

HSP 1 Score: 295.434 bits (755), Expect = 7.345e-97
Identity = 142/209 (67.94%), Postives = 166/209 (79.43%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFG 754
            D  L H+C  DIDS P + RNTGIICTIGPA +S++ L  M+ SGMNVARLNFSHGTHEYHAETIK VREA E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFG
Sbjct:   24 DTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFG 232
[Close]
BLAST of Pyruvate kinase vs. UniProt/SwissProt
Match: sp|P00548|KPYM_CHICK (Pyruvate kinase PKM OS=Gallus gallus OX=9031 GN=PKM PE=2 SV=2)

HSP 1 Score: 655.981 bits (1691), Expect = 0.000e+0
Identity = 314/510 (61.57%), Postives = 394/510 (77.25%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLS---KASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P   RNTGIICTIGPA +S+  L  M+ SGMNVARLNFSHGTHEYH  TIK VREA E+F       RP+AIALDTKGPEIRTGLI+GSGTAE+ L  G  +++  D+ F E CDE  LW+DYKN+  ++D+G+KIY+DDGLISL+V+ KGKD++  +VENGG+LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQNVD+VFASFIR A  +  +R +LGE+GKHI II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKP+ICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  +  +EI    RH  +H E +   A  A + S    A+A+IV+T +G S+HL+S+YRPR PI+AVTRN+  ARQ HL+RG+ P+L + P  D W+EDVD R++  +  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   23 DTFLEHMCRLDIDSEPTIARNTGIICTIGPASRSVDKLKEMIKSGMNVARLNFSHGTHEYHEGTIKNVREATESFASDPITYRPVAIALDTKGPEIRTGLIKGSGTAEVELKKGAALKVTLDNAFMENCDENVLWVDYKNLIKVIDVGSKIYVDDGLISLLVKEKGKDFVMTEVENGGMLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKHIKIISKIENHEGVRRFDEIMEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAMFHRQQFEEIL---RHSVHHREPADAMAAGAVEASFKCLAAALIVMTESGRSAHLVSRYRPRAPIIAVTRNDQTARQAHLYRGVFPVLCKQPAHDAWAEDVDLRVNLGMNVGKARGFFKTGDLVIVLTGWRPGSGYTNTMRVVPV 529
[Close]
BLAST of Pyruvate kinase vs. UniProt/SwissProt
Match: sp|P11974|KPYM_RABIT (Pyruvate kinase PKM OS=Oryctolagus cuniculus OX=9986 GN=PKM PE=1 SV=4)

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 314/507 (61.93%), Postives = 399/507 (78.70%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++TL  M+ SGMNVAR+NFSHGTHEYHAETIK VR A E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++D+G+K+Y+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R ILGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKM+I +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  K  +E+   + H  + +EA A+ +VEA+    A+A+IVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P++ + P  + W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. UniProt/SwissProt
Match: sp|Q5NVN0|KPYM_PONAB (Pyruvate kinase PKM OS=Pongo abelii OX=9601 GN=PKM PE=2 SV=3)

HSP 1 Score: 653.284 bits (1684), Expect = 0.000e+0
Identity = 315/507 (62.13%), Postives = 398/507 (78.50%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++TL  M+ SGMNVARLNFSHGTHEYHAETIK VR A E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE S VANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  K  +E+   + H  + +EA A+ +VEA+    A+A+IVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P+L + P  + W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLLTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSGVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. UniProt/SwissProt
Match: sp|P11980|KPYM_RAT (Pyruvate kinase PKM OS=Rattus norvegicus OX=10116 GN=Pkm PE=1 SV=3)

HSP 1 Score: 651.358 bits (1679), Expect = 0.000e+0
Identity = 315/507 (62.13%), Postives = 396/507 (78.11%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPH---RRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++ L  M+ SGMNVARLNFSHGTHEYHAETIK VR A E+F       RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+KIY+DDGLISL V+ KG DYL  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F     +E+   +    + +EA A+ +VEA+    A+A+IVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P+L +   LD W+EDVD R++ ++  G   G  KKGD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLLFEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. UniProt/SwissProt
Match: sp|P11979|KPYM_FELCA (Pyruvate kinase PKM OS=Felis catus OX=9685 GN=PKM PE=1 SV=2)

HSP 1 Score: 651.358 bits (1679), Expect = 0.000e+0
Identity = 314/507 (61.93%), Postives = 400/507 (78.90%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFK--PHR-RPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS P + RNTGIICTIGPA +S++ L  M+ SGMNVARLNFSHGTHEYHAETIK VR A E+F   P R RP+A+ALDTKGPEIRTGLI+GSGTAE+ L  G  ++I  D+ + EKCDE  LWLDYKNI  ++++G+K+Y+DDGLISL+V+ KG D+L  +VENGG LGSKKGVNLPGA VDLPAVSEKD QDLKFGVEQ+VD+VFASFIR A  + E+R +LGE+GK+I II+KIENHEG++R DEI+E +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  F  K  +E+   + H  + +EA A+ +VEA+    A+A+IVLT +G S+H +++YRPR PI+AVTRN   ARQ HL+RG+ P++ + P  + W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   24 DTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVEILKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPIRYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENVLWLDYKNICKVVEVGSKVYVDDGLISLLVKEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKHGDVVIVLTGWRPGSGFTNTMRVVPV 530
[Close]
BLAST of Pyruvate kinase vs. TrEMBL
Match: A0A267EYV5 (Pyruvate kinase (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig019710g1 PE=3 SV=1)

HSP 1 Score: 671.003 bits (1730), Expect = 0.000e+0
Identity = 319/501 (63.67%), Postives = 400/501 (79.84%), Query Frame = 2 
Query:  146 LSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            L HLC  D+DS+P  VRNTGIICTIGPACKS+  LH M+++GMN+AR+NFSHGTHEYH +T++LVR+A ETFKP  RP+ IALDTKGPEIRTGLI GSGTAE+ LV G+ I +  D  FAE C +  LW+DY NI  +++ G +++IDDGLISL+V+      L C+VENGG LGSKKGVNLPG+ VDLPAVSEKD++DLKF V+  +D+VFASFIRNADAIREIR ILGE GK+I IIAKIENHEG++R DEI+E ADGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKPVICATQMLESM+SKPRPTRAEISDVANAVLDG+DCVMLSGE+AKG FP++AV+TMH+VC+EAE+  + ++  +++K       +    +AIAA EAA   +A+AIIV+TTTG S+ L++++RPRCPIL V+R     RQ HLWRGLHPL  +  R D W+ED+D RI+ +I YG + G + +GD VV+VT WK  +G TNT+R++ V
Sbjct:   39 LEHLCHLDVDSEPAYVRNTGIICTIGPACKSVAILHKMIANGMNIARMNFSHGTHEYHRQTVELVRQAAETFKPWSRPVGIALDTKGPEIRTGLIGGSGTAEVELVRGEPITVTIDSAFAENCSKDTLWVDYPNIVKVINEGGRVFIDDGLISLLVKEIRDKSLLCEVENGGKLGSKKGVNLPGSPVDLPAVSEKDREDLKFAVDLGLDMVFASFIRNADAIREIRHILGEAGKNIKIIAKIENHEGVRRFDEIMEAADGIMVARGDLGIEIPPEKVFLAQKMMIGRCNRAGKPVICATQMLESMISKPRPTRAEISDVANAVLDGADCVMLSGETAKGDFPLEAVRTMHQVCREAESAMYTSQLFEDLKAELLEPTDITHTTAIAASEAANRCRAAAIIVITTTGRSAQLVARHRPRCPILTVSRLAQTCRQAHLWRGLHPLFFDETRSDQWTEDMDKRIEFAIAYGRQRGFINRGDFVVMVTGWKAGTGFTNTLRVIQV 539
[Close]
BLAST of Pyruvate kinase vs. TrEMBL
Match: A0A267F274 (Pyruvate kinase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009984g1 PE=3 SV=1)

HSP 1 Score: 666.381 bits (1718), Expect = 0.000e+0
Identity = 325/501 (64.87%), Postives = 397/501 (79.24%), Query Frame = 2 
Query:  146 LSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            L HLC  DID DP  VRNTGIICTIGPACKS+  LH M+++GMN+AR+NFSHGTHEYH ET++LVR+A +TFK   RP+AIALDTKGPEIRTGLI GSGTAE+ L  G +I + TD   +E C    LW+DY NI  ++  G ++++DDGLISL+V+    + L C+VENGG LGSKKGVNLPGA VDLPAVSEKDK DL+F VE  +DIVFASFIRNA+AIREI+ ILGEEGK+I IIAKIENHEG++R DEI+E ADGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKPVICATQMLESM++KPRPTRAEISDVANAVLDG+DCVMLSGE+AKGS+P++AVKTMH+VC+EAE+  F ++  +++K       +    +AIAA EAA   +A+AIIV+TTTG S+ LIS++RPRCPIL V+R     RQ HL+RGLHPL  + PR + W+ED+D RID +I YG K   +  GD VVIVT WK  +G TNT+RIV V
Sbjct:   31 LEHLCRLDIDLDPAYVRNTGIICTIGPACKSVAVLHKMIAAGMNIARMNFSHGTHEYHKETVELVRQAADTFKGWSRPVAIALDTKGPEIRTGLIGGSGTAEVELKRGSEIVVTTDPAHSENCSADMLWVDYPNIVKVVREGGRVFVDDGLISLLVKEVRDNSLLCEVENGGNLGSKKGVNLPGAPVDLPAVSEKDKSDLRFAVEMGLDIVFASFIRNAEAIREIKHILGEEGKNIKIIAKIENHEGVRRFDEIMEAADGIMVARGDLGIEIPPEKVFLAQKMMIGRCNRAGKPVICATQMLESMITKPRPTRAEISDVANAVLDGADCVMLSGETAKGSYPLEAVKTMHQVCREAESAMFSSQLFEDLKAELLEPTDITHTTAIAASEAANRCRAAAIIVITTTGRSASLISRHRPRCPILTVSRLAQTCRQAHLFRGLHPLFYDAPRCEQWTEDMDKRIDFAIDYGRKREFINVGDFVVIVTGWKAGAGFTNTLRIVQV 531
[Close]
BLAST of Pyruvate kinase vs. TrEMBL
Match: A0A3Q2DAM8 (Pyruvate kinase OS=Cyprinodon variegatus OX=28743 PE=3 SV=1)

HSP 1 Score: 665.611 bits (1716), Expect = 0.000e+0
Identity = 319/507 (62.92%), Postives = 400/507 (78.90%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S++ L  M+ SGMN+AR+NFSHGTHEYHAETIK VREA E+F+P   H RPI IALDTKGPEIRTGLI+GSGTAE+ L  G  I++  DD + E C E+ LWLDYKNIT ++++G+K+YIDDGLISL VQ  G DYL CK++NGG LGSKKGVNLPGA VDLPAVSEKD  DL+FGVEQ VD+VFASFIR AD +  +R++LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  ++++    H  +  EA AI AVEA+  S ASAIIVLT +G S+HL+S+YRPR PI+AVTRN   ARQ HL+RG+ P+L   P  D W+EDVD R++ + + G   G  K+GD V+I+T W+P SG TNT+R+V V
Sbjct:   23 DSFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVEMLKEMIKSGMNIARMNFSHGTHEYHAETIKNVREACESFEPGSIHYRPIGIALDTKGPEIRTGLIKGSGTAEVELKKGHMIKVTLDDAYQENCSEEVLWLDYKNITKVVEVGSKVYIDDGLISLQVQEIGSDYLMCKIDNGGTLGSKKGVNLPGAAVDLPAVSEKDIMDLQFGVEQGVDMVFASFIRKADDVHAVRAVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQVFEDLRRSTPHCKDPAEAIAIGAVEASFKSLASAIIVLTGSGRSAHLLSRYRPRAPIIAVTRNAQTARQAHLYRGIFPVLYTKPSHDVWAEDVDMRVNFAQEMGKARGFFKEGDVVIILTGWRPGSGYTNTMRVVQV 529
[Close]
BLAST of Pyruvate kinase vs. TrEMBL
Match: A0A3Q2EDH1 (Pyruvate kinase OS=Cyprinodon variegatus OX=28743 PE=3 SV=1)

HSP 1 Score: 665.611 bits (1716), Expect = 0.000e+0
Identity = 319/507 (62.92%), Postives = 400/507 (78.90%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S++ L  M+ SGMN+AR+NFSHGTHEYHAETIK VREA E+F+P   H RPI IALDTKGPEIRTGLI+GSGTAE+ L  G  I++  DD + E C E+ LWLDYKNIT ++++G+K+YIDDGLISL VQ  G DYL CK++NGG LGSKKGVNLPGA VDLPAVSEKD  DL+FGVEQ VD+VFASFIR AD +  +R++LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  ++++    H  +  EA AI AVEA+  S ASAIIVLT +G S+HL+S+YRPR PI+AVTRN   ARQ HL+RG+ P+L   P  D W+EDVD R++ + + G   G  K+GD V+I+T W+P SG TNT+R+V V
Sbjct:   47 DSFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVEMLKEMIKSGMNIARMNFSHGTHEYHAETIKNVREACESFEPGSIHYRPIGIALDTKGPEIRTGLIKGSGTAEVELKKGHMIKVTLDDAYQENCSEEVLWLDYKNITKVVEVGSKVYIDDGLISLQVQEIGSDYLMCKIDNGGTLGSKKGVNLPGAAVDLPAVSEKDIMDLQFGVEQGVDMVFASFIRKADDVHAVRAVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQVFEDLRRSTPHCKDPAEAIAIGAVEASFKSLASAIIVLTGSGRSAHLLSRYRPRAPIIAVTRNAQTARQAHLYRGIFPVLYTKPSHDVWAEDVDMRVNFAQEMGKARGFFKEGDVVIILTGWRPGSGYTNTMRVVQV 553
[Close]
BLAST of Pyruvate kinase vs. TrEMBL
Match: A0A3Q2DAL9 (Pyruvate kinase OS=Cyprinodon variegatus OX=28743 PE=3 SV=1)

HSP 1 Score: 664.84 bits (1714), Expect = 0.000e+0
Identity = 319/507 (62.92%), Postives = 400/507 (78.90%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S++ L  M+ SGMN+AR+NFSHGTHEYHAETIK VREA E+F+P   H RPI IALDTKGPEIRTGLI+GSGTAE+ L  G  I++  DD + E C E+ LWLDYKNIT ++++G+K+YIDDGLISL VQ  G DYL CK++NGG LGSKKGVNLPGA VDLPAVSEKD  DL+FGVEQ VD+VFASFIR AD +  +R++LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  ++++    H  +  EA AI AVEA+  S ASAIIVLT +G S+HL+S+YRPR PI+AVTRN   ARQ HL+RG+ P+L   P  D W+EDVD R++ + + G   G  K+GD V+I+T W+P SG TNT+R+V V
Sbjct:  122 DSFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVEMLKEMIKSGMNIARMNFSHGTHEYHAETIKNVREACESFEPGSIHYRPIGIALDTKGPEIRTGLIKGSGTAEVELKKGHMIKVTLDDAYQENCSEEVLWLDYKNITKVVEVGSKVYIDDGLISLQVQEIGSDYLMCKIDNGGTLGSKKGVNLPGAAVDLPAVSEKDIMDLQFGVEQGVDMVFASFIRKADDVHAVRAVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQVFEDLRRSTPHCKDPAEAIAIGAVEASFKSLASAIIVLTGSGRSAHLLSRYRPRAPIIAVTRNAQTARQAHLYRGIFPVLYTKPSHDVWAEDVDMRVNFAQEMGKARGFFKEGDVVIILTGWRPGSGYTNTMRVVQV 628
[Close]
BLAST of Pyruvate kinase vs. Ensembl Cavefish
Match: pkma (pyruvate kinase PKM [Source:NCBI gene;Acc:103044212])

HSP 1 Score: 658.677 bits (1698), Expect = 0.000e+0
Identity = 315/507 (62.13%), Postives = 396/507 (78.11%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S+  L  M+ SGMN+ARLNFSHG+HEYH ETIK +REA E+F+P   H RPI IALDTKGPEIRTGLI+GSGTAE+ L  G  I++  DD + E CDE  LWLDYKNIT +++IG+K+YIDDGLISL VQ  G DY+ C++ENGG LGSKKGVNLPGA VDLPAVSEKD +DL+FGVE  VD+VFASFIR A  + E+R +LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  +E++  N+  ++  EA AI AVE++    ASAIIVLT +G S+HLIS+YRPR PI+AVTRN   ARQ HL+RG+ P+    P  D W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   48 DTFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVDMLKEMIKSGMNIARLNFSHGSHEYHGETIKNIREATESFEPGSIHYRPIGIALDTKGPEIRTGLIKGSGTAEVELKKGNTIKVTLDDAYMENCDEDVLWLDYKNITKVVEIGSKVYIDDGLISLQVQEIGSDYILCEIENGGTLGSKKGVNLPGAAVDLPAVSEKDIKDLQFGVEMGVDMVFASFIRKAQDVNEVRQVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQLFEELRRANKMTHDPSEAVAIGAVESSFKCCASAIIVLTKSGRSAHLISRYRPRAPIIAVTRNGQTARQAHLYRGIFPVFYNKPAHDVWAEDVDLRVNFAMDVGKARGFFKTGDVVIVLTGWRPGSGFTNTMRVVPV 554
[Close]
BLAST of Pyruvate kinase vs. Ensembl Cavefish
Match: pkma (pyruvate kinase PKM [Source:NCBI gene;Acc:103044212])

HSP 1 Score: 657.136 bits (1694), Expect = 0.000e+0
Identity = 315/507 (62.13%), Postives = 396/507 (78.11%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S+  L  M+ SGMN+ARLNFSHG+HEYH ETIK +REA E+F+P   H RPI IALDTKGPEIRTGLI+GSGTAE+ L  G  I++  DD + E CDE  LWLDYKNIT +++IG+K+YIDDGLISL VQ  G DY+ C++ENGG LGSKKGVNLPGA VDLPAVSEKD +DL+FGVE  VD+VFASFIR A  + E+R +LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  +E++  N+  ++  EA AI AVE++    ASAIIVLT +G S+HLIS+YRPR PI+AVTRN   ARQ HL+RG+ P+    P  D W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:  123 DTFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVDMLKEMIKSGMNIARLNFSHGSHEYHGETIKNIREATESFEPGSIHYRPIGIALDTKGPEIRTGLIKGSGTAEVELKKGNTIKVTLDDAYMENCDEDVLWLDYKNITKVVEIGSKVYIDDGLISLQVQEIGSDYILCEIENGGTLGSKKGVNLPGAAVDLPAVSEKDIKDLQFGVEMGVDMVFASFIRKAQDVNEVRQVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQLFEELRRANKMTHDPSEAVAIGAVESSFKCCASAIIVLTKSGRSAHLISRYRPRAPIIAVTRNGQTARQAHLYRGIFPVFYNKPAHDVWAEDVDLRVNFAMDVGKARGFFKTGDVVIVLTGWRPGSGFTNTMRVVPV 629
[Close]
BLAST of Pyruvate kinase vs. Ensembl Cavefish
Match: pkma (pyruvate kinase PKM [Source:NCBI gene;Acc:103044212])

HSP 1 Score: 657.136 bits (1694), Expect = 0.000e+0
Identity = 315/507 (62.13%), Postives = 396/507 (78.11%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S+  L  M+ SGMN+ARLNFSHG+HEYH ETIK +REA E+F+P   H RPI IALDTKGPEIRTGLI+GSGTAE+ L  G  I++  DD + E CDE  LWLDYKNIT +++IG+K+YIDDGLISL VQ  G DY+ C++ENGG LGSKKGVNLPGA VDLPAVSEKD +DL+FGVE  VD+VFASFIR A  + E+R +LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  +E++  N+  ++  EA AI AVE++    ASAIIVLT +G S+HLIS+YRPR PI+AVTRN   ARQ HL+RG+ P+    P  D W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   78 DTFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVDMLKEMIKSGMNIARLNFSHGSHEYHGETIKNIREATESFEPGSIHYRPIGIALDTKGPEIRTGLIKGSGTAEVELKKGNTIKVTLDDAYMENCDEDVLWLDYKNITKVVEIGSKVYIDDGLISLQVQEIGSDYILCEIENGGTLGSKKGVNLPGAAVDLPAVSEKDIKDLQFGVEMGVDMVFASFIRKAQDVNEVRQVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQLFEELRRANKMTHDPSEAVAIGAVESSFKCCASAIIVLTKSGRSAHLISRYRPRAPIIAVTRNGQTARQAHLYRGIFPVFYNKPAHDVWAEDVDLRVNFAMDVGKARGFFKTGDVVIVLTGWRPGSGFTNTMRVVPV 584
[Close]
BLAST of Pyruvate kinase vs. Ensembl Cavefish
Match: pkma (pyruvate kinase PKM [Source:NCBI gene;Acc:103044212])

HSP 1 Score: 656.751 bits (1693), Expect = 0.000e+0
Identity = 315/507 (62.13%), Postives = 396/507 (78.11%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S+  L  M+ SGMN+ARLNFSHG+HEYH ETIK +REA E+F+P   H RPI IALDTKGPEIRTGLI+GSGTAE+ L  G  I++  DD + E CDE  LWLDYKNIT +++IG+K+YIDDGLISL VQ  G DY+ C++ENGG LGSKKGVNLPGA VDLPAVSEKD +DL+FGVE  VD+VFASFIR A  + E+R +LGE+GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  +E++  N+  ++  EA AI AVE++    ASAIIVLT +G S+HLIS+YRPR PI+AVTRN   ARQ HL+RG+ P+    P  D W+EDVD R++ ++  G   G  K GD V+++T W+P SG TNT+R+V V
Sbjct:   50 DTFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVDMLKEMIKSGMNIARLNFSHGSHEYHGETIKNIREATESFEPGSIHYRPIGIALDTKGPEIRTGLIKGSGTAEVELKKGNTIKVTLDDAYMENCDEDVLWLDYKNITKVVEIGSKVYIDDGLISLQVQEIGSDYILCEIENGGTLGSKKGVNLPGAAVDLPAVSEKDIKDLQFGVEMGVDMVFASFIRKAQDVNEVRQVLGEKGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQLFEELRRANKMTHDPSEAVAIGAVESSFKCCASAIIVLTKSGRSAHLISRYRPRAPIIAVTRNGQTARQAHLYRGIFPVFYNKPAHDVWAEDVDLRVNFAMDVGKARGFFKTGDVVIVLTGWRPGSGFTNTMRVVPV 556
[Close]
BLAST of Pyruvate kinase vs. Ensembl Cavefish
Match: pkmb (pyruvate kinase PKM-like [Source:NCBI gene;Acc:103047790])

HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0
Identity = 312/507 (61.54%), Postives = 396/507 (78.11%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D +L H+C  DIDS+P   RNTGIICTIGPA +S++ L  M+ +GMN+ARLNFSHGTHEYHAETIK VREA E+F P     RP+AIALDTKGPEIRTGLI+GSGT E+ L  G +I++  DD + + CDEK LWLDYKNIT ++  G+ IY+DDGLISL V   G DYL C++ENGG+LGSKKGVNLPGA +DLPAVSEKD QDL+FGVEQ VD+VFASFIR A  ++ +R +LGE+GK I +I+K+ENHEG++R DEI+E +DGIMVARGDMGIEIP +KV +AQKMMI++ N+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P+++V+T H++ +EAEA  F  +  +E++ +     +  E+ AI AVEA+    AS IIVLT +G S+HL+SKYRPR PILAVTRNE  ARQ HL+RG++P+L   P  D W+EDVD R++ +++ G      K GD V++VT W+P SG TNT+R+V V
Sbjct:   23 DTLLEHMCLLDIDSEPAVYRNTGIICTIGPASRSVEKLREMIKAGMNIARLNFSHGTHEYHAETIKNVREATESFGPGTLEYRPVAIALDTKGPEIRTGLIKGSGTEEVTLNKGDKIKLTLDDKYKDNCDEKTLWLDYKNITKVVQQGSHIYVDDGLISLKVIEVGGDYLTCEIENGGMLGSKKGVNLPGANIDLPAVSEKDTQDLQFGVEQGVDMVFASFIRKAADVQAVRKVLGEKGKEIRVISKLENHEGVRRFDEILEASDGIMVARGDMGIEIPTEKVFLAQKMMISRSNRIGKPITCATQMLESMIKKPRPTRAESSDVANAVLDGADCIMLSGETAKGEYPVESVRTQHQIAREAEAAMFHRQVFEELRRITHLTRDPCESVAIGAVEASFKCCASGIIVLTKSGRSAHLLSKYRPRAPILAVTRNEQTARQSHLYRGIYPILYNKPANDVWAEDVDLRVNFALEMGKFRKFFKSGDVVIVVTGWRPGSGYTNTMRVVLV 529
[Close]
BLAST of Pyruvate kinase vs. Ensembl Sea Lamprey
Match: pkma (pyruvate kinase M1/2a [Source:ZFIN;Acc:ZDB-GENE-031201-4])

HSP 1 Score: 622.468 bits (1604), Expect = 0.000e+0
Identity = 299/523 (57.17%), Postives = 400/523 (76.48%), Query Frame = 2 
Query:  116 RIMKNKPDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRG-------SGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQ--AKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            ++  ++ D  L H+C  DIDS+P + RNTGIICTIGPA +S+ TL  M+ SGMN+AR+NFSHG+HEYH++TIK VREA E+F     + RP+ +ALDTKGPEIRTGLI+G       SGTAE+ L  G ++++  DD + + CD+  +WLDYKNIT ++  G+KI++DDGLISL+V+   KG DY+  +VENGG+LGS+KGVNLPGA VDLPAVS KD QDL+FGV+Q VD+VFASFIR A  + E+R++LGE+GK+I II+KIENHEG++R +EI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKPVICATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+  H + +EAEA  +  +  +E++ ++   ++  E +AI  VEA+    A AIIVLT +G S+HL+SKYRPR PI+AVTR    ARQ HL+RG+ P+L   P  D W+EDVD R++ +++ G   G  K+ D V++VT W+P SG TN +R++ V
Sbjct:   17 QLSASRADTFLEHMCLLDIDSEPITARNTGIICTIGPASRSLDTLKEMIKSGMNIARMNFSHGSHEYHSDTIKNVREATESFAGNPIYYRPVGVALDTKGPEIRTGLIKGAVVVAAQSGTAEVELKKGAELKVTLDDAYQDACDDTMVWLDYKNITKVVTPGSKIFVDDGLISLLVKEIGKGDDYVITEVENGGMLGSRKGVNLPGAAVDLPAVSAKDVQDLQFGVDQGVDMVFASFIRKAADVEEVRAVLGEKGKNIKIISKIENHEGVRRFEEILEASDGIMVARGDLGIEIPGEKVFIAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAESSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAMYHRQLFEELRRLSGITSDPTETTAIGTVEASFKCSAGAIIVLTKSGRSAHLLSKYRPRAPIIAVTRCGQTARQAHLYRGIFPVLCREPVNDVWAEDVDLRVNLAMEVGKCRGFFKQDDVVIVVTGWRPGSGYTNMMRVIKV 539
[Close]
BLAST of Pyruvate kinase vs. Ensembl Yeast
Match: CDC19 (Pyruvate kinase; functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; regulated via allosteric activation by fructose bisphosphate; CDC19 has a paralog, PYK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000036])

HSP 1 Score: 460.685 bits (1184), Expect = 2.131e-158
Identity = 241/488 (49.39%), Postives = 330/488 (67.62%), Query Frame = 2 
Query:  191 VRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISL-IVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAE-AIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            +R T II TIGP   + +TL  +  +G+N+ R+NFSHG++EYH   I   R++ E +    RP+AIALDTKGPEIRTG    +   +  +    ++   TDD +A+ CD+K +++DYKNIT ++  G  IY+DDG++S  +++      L  K  N G + S KGVNLPG  VDLPA+SEKDK+DL+FGV+  V +VFASFIR A+ +  IR +LGE+GK + II KIEN +G+   DEI++  DG+MVARGD+GIEIPA +V+  QK +IAK N  GKPVICATQMLESM   PRPTRAE+SDV NA+LDG+DCVMLSGE+AKG++PI AV TM E    AE AI +   Y  +++N      +  E  A +AV A    KA AIIVL+T+G +  L+SKYRP CPI+ VTR    AR  HL+RG+ P + E   + +W++DV+ARI+  I+   + GILKKGD+ V +  +K  +G +NT+++  V
Sbjct:   18 LRRTSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYP--GRPLAIALDTKGPEIRTGTT--TNDVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAGKICSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAVIAEQAIAYLPNY-DDMRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAARFSHLYRGVFPFVFEKEPVSDWTDDVEARINFGIEKAKEFGILKKGDTYVSIQGFKAGAGHSNTLQVSTV 500
[Close]
BLAST of Pyruvate kinase vs. Ensembl Yeast
Match: PYK2 (Pyruvate kinase; appears to be modulated by phosphorylation; transcription repressed by glucose, and Pyk2p may be active under low glycolytic flux; PYK2 has a paralog, CDC19, that arose from the whole genome duplication [Source:SGD;Acc:S000005874])

HSP 1 Score: 432.565 bits (1111), Expect = 2.269e-147
Identity = 230/506 (45.45%), Postives = 319/506 (63.04%), Query Frame = 2 
Query:  134 PDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISL-IVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            P+  L  L +  I + P  +R T II TIGP   S + +  +  +G+N+ RLNFSHG++E+H   I+   ++ + F    RP+AIALDTKGPEIRTG  R     ++++    Q+   TD  FA   ++K +++DY N+T ++  G  IY+DDG++S  ++Q   +  L  +  N G + S KGVNLP   VDLP +S KD +DL+FGV   + IVFASFIR ++ +  IR  LG EG+ I II+KIEN +G+   DEI+E  DG+M+ARGD+GIEI A +V+  QK +IAKCN  GKPVICATQML+SM   PRPTRAE+SDV NAVLDG+DCVMLSGE+AKG +P+ AV  M      AE+         ++++      +  E  A AA  A       AI+VL+TTGN++ L+SKYRP CPI+ VTR+   AR  HL+RG+ P L E  RLD+W EDV  R+   ++     G++  GD+VV +  +K   G +NT+RI  V
Sbjct:    2 PESRLQRLANLKIGT-PQQLRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFHQSVIENAVKSEQQFP--GRPLAIALDTKGPEIRTG--RTLNDQDLYIPVDHQMIFTTDASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYIASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIRKALGSEGQDIKIISKIENQQGLDNFDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIAKCNLAGKPVICATQMLDSMTHNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGDYPVNAVNIMAATALIAESTIAHLALYDDLRDATPKPTSTTETVAAAATAAILEQDGKAIVVLSTTGNTARLLSKYRPSCPIILVTRHARTARIAHLYRGVFPFLYEPKRLDDWGEDVHRRLKFGVEMARSFGMVDNGDTVVSIQGFKGGVGHSNTLRISTV 502
[Close]
BLAST of Pyruvate kinase vs. Ensembl Yeast
Match: YAL037C-B_mRNA (Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching [Source:SGD;Acc:S000028592])

HSP 1 Score: 101.293 bits (251), Expect = 4.377e-24
Identity = 79/296 (26.69%), Postives = 152/296 (51.35%), Query Frame = -3 
Query:  692 ISFLQNSGFVSVLDRAIYSCIDIFTPIIQSRKLN**WMESPPQMALSCNDFISSHCKNWTTRAIFRN*M*RISGRCQHNNR*SFRQLXXXXXXXXXXFYMVVEMSIHILYFLKIFILKENCFSFFTYFVHGFNCLDRKGAFS*FSR*HDTITSI*NGIGDITNFCSSRSGFRNHRFEHLGSTNDRLSLFIAFCNHHFLSNNYFLSRNFDSHVTSCNHYSVGFFDDFINSFDTFMVXXXXXXXXXXXXXXXXXXXXXXSICISNERSENNVNILFDTEF*ILFIFFRDRG*IDLGSW 1579
            ++ LQ++ F+S+ +  + +  +I +P+         W ++  Q+  S + + S +  +WT  ++  N     +G  Q N+        S +      F     +   + + + ++ + ++ FS  + F H  N +D       F+R H+T+++I + + DI NF S  S   +H F+HLGST++ L+  +   N   L +  F   +F++ VTS NH +V    DF+   +T +VFN  N+ ++ + F+++ S+  N +  S+ERSE++V+ + DTE  I  + FR    ID+G+W
Sbjct:   29 VTLLQDTEFLSLFNTEVDTGFNIISPVRDRFLFENEWEDTSVQVRESSSSWASGNQDDWTVWSVLGNQSWGGTGSGQDNDSLGLLFENSSDSGGSDGFGGGGWLWSTVSHVIVVWQVSDSLFSNDSGFSHSGNGVDWVVTLGGFTRQHNTVSTIQDSVTDIGNFSSGWSWVVSHGFQHLGSTDNWLTSQVRLSNQFLLDSQDFWGWDFNTQVTSGNHNTVSDLQDFVEVVNTLLVFNLDNDLDVLTLFTQDFSDGQNIVGGSDERSEDHVDTVLDTESQIFLVLFRQSWQIDIGTW 324
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BLAST of Pyruvate kinase vs. Ensembl Nematostella
Match: EDO49963 (Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:A7RER9])

HSP 1 Score: 531.176 bits (1367), Expect = 0.000e+0
Identity = 265/494 (53.64%), Postives = 358/494 (72.47%), Query Frame = 2 
Query:  167 DIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            DID  P ++RN+G++CTIGPA +S++ +  ++ +GMN+ARLNFSHGTHEYH ETI  +R A     PH   + IALDTKGPEIRTGL++     EI L  GQ++++ TD    ++   + +++DY+NI  ++ IG  +Y+DDGLISL V  KG ++L  +V N  LLGSKKGVNLP   VDLPAVSE+DK+D+ F VE  VD++FASFIR  + I EIR +L +  K+I I+AKIENHEG++R +EI+E ADGIMVARGD+GIEIPA+KV +AQKMMIA+CN +G PVICATQMLESMV  PRPTRAE SDVANA+LDG+DCVMLSGE+AKG +P+QAV  MH + +EAEA  F  +   E+++    + +   ++AIAAV A+  + A AII LT TG ++ +++++RPRCPI+ VTR+  VARQ HLWRG  P++ +   LDN  E+ D R+D ++  G K G L  G + V V+ WK  +  TNT+RI+ +
Sbjct:   37 DIDKHPLTIRNSGVVCTIGPASRSVEIVAQLIENGMNIARLNFSHGTHEYHRETIMNIRRAALLEWPH--AVGIALDTKGPEIRTGLLKA---GEIKLEKGQKLKVSTDKAMYDQGHTECIFVDYENIVKVVQIGGTVYVDDGLISLKVLEKGDNFLITEVLNDALLGSKKGVNLPNCAVDLPAVSEQDKKDIAFAVEMEVDMIFASFIRKPEDIAEIRKLLEKHAKNIKIVAKIENHEGVRRFNEILEVADGIMVARGDLGIEIPAEKVFLAQKMMIARCNMKGVPVICATQMLESMVQNPRPTRAETSDVANAILDGADCVMLSGETAKGLYPVQAVAMMHRISREAEAAIFHKQSFDELRHNLEGYADTHISTAIAAVAASFTAGADAIICLTHTGRTAAVVARFRPRCPIVVVTRDPRVARQMHLWRGCFPIVYDQEPLDNVLEEHDQRLDFALGMGKKMGFLTIGSTFVFVSGWKSGAAHTNTLRILTL 525
[Close]
BLAST of Pyruvate kinase vs. Ensembl Medaka
Match: pkma (pyruvate kinase PKM [Source:NCBI gene;Acc:101170748])

HSP 1 Score: 660.603 bits (1703), Expect = 0.000e+0
Identity = 319/507 (62.92%), Postives = 398/507 (78.50%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S++ L  M+ SGMN+AR+NFSHG+HEYHAETIK VREA E+F P     RPI IALDTKGPEIRTGLIRGSGTAE+ L  G  I+I  DD + E C E+NLWLDYKNIT +++IG+KIYIDDGLISL V   G D++ C++ENGG LGSKKGVNLPGA VDLPAVSEKD QDL+FGVEQ VD+VFASFIR A  +  +R +LGE GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  ++++    H ++  EA AI AVEA+  S ASAIIVLT +G S+HLIS+YRPR PILAVTRN   ARQ HL+RG+ P+L   P  D W+EDVD R++ +++ G   G  K+GD V+++T W+P SG TNT+R++ V
Sbjct:   25 DSFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVEMLKEMIKSGMNIARMNFSHGSHEYHAETIKNVREACESFVPGSIQYRPIGIALDTKGPEIRTGLIRGSGTAEVELKKGNTIKITLDDAYQENCSEENLWLDYKNITKVVEIGSKIYIDDGLISLQVVEIGSDFIICEIENGGTLGSKKGVNLPGAAVDLPAVSEKDIQDLQFGVEQGVDMVFASFIRKAADVHAVRKVLGERGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQVFEDLRRSTPHCSDPAEAIAIGAVEASFKSLASAIIVLTGSGRSAHLISRYRPRAPILAVTRNAQTARQAHLYRGIFPVLYTKPAHDVWAEDVDMRVNFAMEMGKARGFFKEGDVVIVLTGWRPGSGYTNTMRVILV 531
[Close]
BLAST of Pyruvate kinase vs. Ensembl Medaka
Match: pkma (pyruvate kinase PKM [Source:NCBI gene;Acc:101170748])

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 316/507 (62.33%), Postives = 395/507 (77.91%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S++ L  M+ SGMN+AR+NFSHG+HEYHAETIK VREA E+F P     RPI IALDTKGPEIRTGLIRGSGTAE+ L  G  I+I  DD + E C E+NLWLDYKNIT +++IG+KIYIDDGLISL V   G D++ C++ENGG LGSKKGVNLPGA VDLPAVSEKD QDL+FGVEQ VD+VFASFIR A  +  +R +LGE GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  +E++   +   +  EA A+ AVE++    ASAII LT TG S+HLIS+YRPR PILAVTRN   ARQ HL+RG+ P+L   P  D W+EDVD R++ +++ G   G  K+GD V+++T W+P SG TNT+R++ V
Sbjct:   43 DSFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVEMLKEMIKSGMNIARMNFSHGSHEYHAETIKNVREACESFVPGSIQYRPIGIALDTKGPEIRTGLIRGSGTAEVELKKGNTIKITLDDAYQENCSEENLWLDYKNITKVVEIGSKIYIDDGLISLQVVEIGSDFIICEIENGGTLGSKKGVNLPGAAVDLPAVSEKDIQDLQFGVEQGVDMVFASFIRKAADVHAVRKVLGERGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAATFHRQLFEELRRHTQLTRDPSEAVAVGAVESSFKCCASAIITLTKTGRSAHLISRYRPRAPILAVTRNAQTARQAHLYRGIFPVLYTKPAHDVWAEDVDMRVNFAMEMGKARGFFKEGDVVIVLTGWRPGSGYTNTMRVILV 549
[Close]
BLAST of Pyruvate kinase vs. Ensembl Medaka
Match: pkma (pyruvate kinase PKM [Source:NCBI gene;Acc:101170748])

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 316/507 (62.33%), Postives = 395/507 (77.91%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  L H+C  DIDS+P + RNTGIICTIGPA +S++ L  M+ SGMN+AR+NFSHG+HEYHAETIK VREA E+F P     RPI IALDTKGPEIRTGLIRGSGTAE+ L  G  I+I  DD + E C E+NLWLDYKNIT +++IG+KIYIDDGLISL V   G D++ C++ENGG LGSKKGVNLPGA VDLPAVSEKD QDL+FGVEQ VD+VFASFIR A  +  +R +LGE GK+I II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMMI +CN+ GKP+ CATQMLESM+ KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV+T H + +EAEA  F  +  +E++   +   +  EA A+ AVE++    ASAII LT TG S+HLIS+YRPR PILAVTRN   ARQ HL+RG+ P+L   P  D W+EDVD R++ +++ G   G  K+GD V+++T W+P SG TNT+R++ V
Sbjct:   25 DSFLEHMCLLDIDSEPTTARNTGIICTIGPASRSVEMLKEMIKSGMNIARMNFSHGSHEYHAETIKNVREACESFVPGSIQYRPIGIALDTKGPEIRTGLIRGSGTAEVELKKGNTIKITLDDAYQENCSEENLWLDYKNITKVVEIGSKIYIDDGLISLQVVEIGSDFIICEIENGGTLGSKKGVNLPGAAVDLPAVSEKDIQDLQFGVEQGVDMVFASFIRKAADVHAVRKVLGERGKNIKIISKLENHEGVRRFDEIMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRAGKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAATFHRQLFEELRRHTQLTRDPSEAVAVGAVESSFKCCASAIITLTKTGRSAHLISRYRPRAPILAVTRNAQTARQAHLYRGIFPVLYTKPAHDVWAEDVDMRVNFAMEMGKARGFFKEGDVVIVLTGWRPGSGYTNTMRVILV 531
[Close]
BLAST of Pyruvate kinase vs. Ensembl Medaka
Match: pkmb (pyruvate kinase PKM [Source:NCBI gene;Acc:101170426])

HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0
Identity = 307/507 (60.55%), Postives = 390/507 (76.92%), Query Frame = 2 
Query:  137 DCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNV 1648
            D  + H+C  DIDS+P   RNTGI+CTIGPA +S+     M+ +GMN+AR+NFSHGTHEYHAETIK VREA E+F P     RP+AIALDTKGPEIRTGLI+GSGTAE+ L  GQ I++  DD + + CDE  LW+DYKNIT +L +GN +YIDDGLISL V+  G DYL C++ENGGLLGSKKGVNLPGA VDLPA+SEKD QDL+FG+EQ VD+VFASFIR A  ++ +R +LGE+GK + II+K+ENHEG++R DEI+E +DGIMVARGD+GIEIP +KV +AQKMM  KCN+ GKP+ICATQMLESM  KPRPTRAE SDVANAVLDG+DC+MLSGE+AKG +P++AV T H + +EAEA  F  +  +E++  +    +  E+ AI AVEA+    ASAIIVLT +G S++++S+YRPR PILAVTR    ARQ HL+RG++P+L      D W+EDVD R++ +++YG      K GD  ++VT W+P SG TNT+R+V V
Sbjct:   23 DTYIEHMCLLDIDSEPAVSRNTGIVCTIGPASRSVDMAKEMIKAGMNIARMNFSHGTHEYHAETIKNVREATESFGPGTVEYRPVAIALDTKGPEIRTGLIKGSGTAEVELKKGQNIKLTLDDKYKDNCDENYLWVDYKNITKVLQVGNNVYIDDGLISLKVKEVGNDYLMCEIENGGLLGSKKGVNLPGAAVDLPALSEKDIQDLQFGLEQGVDMVFASFIRKAADVQAVRKVLGEKGKDVKIISKLENHEGVRRFDEILEASDGIMVARGDLGIEIPTEKVFIAQKMMTGKCNRIGKPIICATQMLESMTKKPRPTRAEASDVANAVLDGNDCIMLSGETAKGDYPLEAVLTQHRIAREAEAAMFHRQMFEELRRTSHLTRDPTESVAIGAVEASFKCCASAIIVLTKSGRSAYMLSRYRPRAPILAVTRCGQTARQAHLYRGVYPVLYTKNANDVWAEDVDMRVNFAMEYGKYRKFFKSGDVAIVVTGWRPGSGYTNTMRVVLV 529
[Close]
BLAST of Pyruvate kinase vs. Ensembl Medaka
Match: pklr (pyruvate kinase PKM [Source:NCBI gene;Acc:101161188])

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 286/538 (53.16%), Postives = 382/538 (71.00%), Query Frame = 2 
Query:   47 ILQILKMSTNSSSVEKSDSLTQ*RIM-KNKPDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKP---HRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQ-VDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVN 1645
            +L   ++   S  +   DS  Q + +  +  D  L HLC  DID +P + RNT IICTIGPA +SI+ L  M+ +GMN+ARLNFSHG HEYH+ETIK +REA+ET      + RP+AIALDTKGPEIRTGL++G    E+ LV G  +R+VT +   +K D   +W+DY ++  +L+ G +IYIDDGL++L V   G D++D  VE GGLL S+KGVNLPG   + L AVSE+D+ DL+FGV   VD+VFASFIR+A  ++++R  LGE G HI +I+K+E+ +G++  +EI+ E+DG+MVARGD+GIEIPA+KV +AQKMMI +CN  GKPVICATQMLESMVS PRPTRAE SDVANAVLDG+DCVMLS E+AKG FP++AV  MH +C+EAEA  F ++  +E++ +    ++  E +AI AVE++    A AIIVLT++G SSHL+S+YRPRCPI+AVTR+  VARQ  L RG+ P L        W++DVD+R+   +  G   G  K GD V++VT W P SG TN +R V+
Sbjct:    4 LLNAARLRRYSDLMTMPDSFIQRQQLDASMADTFLEHLCLLDIDQEPITARNTSIICTIGPASRSIQKLQEMVKAGMNIARLNFSHGCHEYHSETIKNIREAVETITSDPLYYRPVAIALDTKGPEIRTGLVKGKVDEEVQLVKGSHVRVVTAESERDKTDATMVWVDYPHLPKVLEKGRRIYIDDGLLALKVLEIGSDWVDTVVEAGGLLCSRKGVNLPGCDLIGLQAVSEQDEADLRFGVAHGVDMVFASFIRSAQDVKDVRRALGELGSHIKVISKVESRQGVQNFEEILAESDGVMVARGDLGIEIPAEKVFIAQKMMIGRCNSAGKPVICATQMLESMVSHPRPTRAESSDVANAVLDGADCVMLSAETAKGKFPLEAVAMMHSICREAEAAIFHHQLFEELRRLTPLSSDPTEVTAIGAVESSFKCCAGAIIVLTSSGRSSHLLSRYRPRCPIIAVTRSPQVARQSQLLRGVFPALFHPLPAPVWADDVDSRVKFGMDIGKARGFFKSGDMVIVVTGWIPGSGHTNIMRAVH 541
[Close]
BLAST of Pyruvate kinase vs. Planmine SMEST
Match: SMESG000006009.1 (SMESG000006009.1)

HSP 1 Score: 1048.88 bits (2711), Expect = 0.000e+0
Identity = 524/529 (99.05%), Postives = 525/529 (99.24%), Query Frame = 2 
Query:   65 MSTNSSSVEKSDSLTQ*RIMKNKPDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            MSTNSSSVEKSDSLTQ R MKNKPDCVLSHLCD DIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEI+LVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHVEASAIAAVEAAQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVT WKPVSGSTNTIRIVNVD
Sbjct:    1 MSTNSSSVEKSDSLTQKRFMKNKPDCVLSHLCDLDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEINLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHVEASAIAAVEAAQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTGWKPVSGSTNTIRIVNVD 529
[Close]
BLAST of Pyruvate kinase vs. Planmine SMEST
Match: SMESG000006014.1 (SMESG000006014.1)

HSP 1 Score: 1043.11 bits (2696), Expect = 0.000e+0
Identity = 522/529 (98.68%), Postives = 523/529 (98.87%), Query Frame = 2 
Query:   65 MSTNSSSVEKSDSLTQ*RIMKNKPDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            MSTNSSSVEKSDSLTQ R MKNK DCVLSHLCD DIDSDPGSVRNTGIICTI PACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHVEASAIAAVEAAQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVT WKPVSGSTNTIRIVNV+
Sbjct:    1 MSTNSSSVEKSDSLTQKRFMKNKLDCVLSHLCDLDIDSDPGSVRNTGIICTIEPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHVEASAIAAVEAAQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTGWKPVSGSTNTIRIVNVN 529
[Close]
BLAST of Pyruvate kinase vs. Planmine SMEST
Match: SMESG000068454.1 (SMESG000068454.1)

HSP 1 Score: 768.074 bits (1982), Expect = 0.000e+0
Identity = 371/502 (73.90%), Postives = 434/502 (86.45%), Query Frame = 2 
Query:  146 LSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            L+HLCD DID  P  +RNTGIICTIGPAC +I TLHGM+++GMN+ARLNFSHGTH+YH  ++KL+ EA  T++   RPI+IALDTKGPEIRTGLI GS TAEI L +G++IRIVT++ FA KCD K +WLDYKN+ NIL I ++IYIDDGLISLIV  KG+DYLDC++ENGG LGSKKGVNLPGA VDLPAVSEKDK DL FGV+  VDIVFASFIRNA AIREIRSILG+ GK+ILIIAKIEN+EG+KRIDEII+ ADGIMVARGD+GIEIPA+KVV AQKMMIAKCN++GKPVICATQMLESMV+K RPTRAEISDVANAVLDGSDCVMLSGE+AKG FP+Q V TMHEVCKE E++FFQN+YLQE+K+ ++++ + +E SA+AAVEAAQLS A AI+VLTTTG S+HLI+KYRP CPILAVTRNE+VARQCHLWRGLHPLL   P   NWS+DVDARI  SI+YG + G  K GD +V+VT WKP  GSTNT+RI+N+D
Sbjct:   20 LNHLCDLDIDKKPFIIRNTGIICTIGPACNNIATLHGMIAAGMNIARLNFSHGTHDYHVNSLKLIHEASNTYQAAYRPISIALDTKGPEIRTGLINGSETAEILLNEGEKIRIVTNEKFANKCDNKTIWLDYKNVVNILKIESRIYIDDGLISLIVIGKGEDYLDCEIENGGSLGSKKGVNLPGAYVDLPAVSEKDKADLLFGVKHKVDIVFASFIRNAAAIREIRSILGDAGKYILIIAKIENYEGVKRIDEIIDAADGIMVARGDLGIEIPAEKVVAAQKMMIAKCNRKGKPVICATQMLESMVTKARPTRAEISDVANAVLDGSDCVMLSGETAKGKFPVQTVHTMHEVCKEGESMFFQNRYLQELKSDSKYYGDAIETSAVAAVEAAQLSSAHAIVVLTTTGKSAHLIAKYRPSCPILAVTRNEIVARQCHLWRGLHPLLCTLPCFQNWSDDVDARISYSIEYGCEQGFFKTGDLIVLVTGWKPTPGSTNTVRIINID 521
[Close]
BLAST of Pyruvate kinase vs. Planmine SMEST
Match: SMESG000017675.1 (SMESG000017675.1)

HSP 1 Score: 695.271 bits (1793), Expect = 0.000e+0
Identity = 328/512 (64.06%), Postives = 417/512 (81.45%), Query Frame = 2 
Query:  116 RIMKNKPDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIVNVD 1651
            RI  N     L H    + + +PG +RN+GIICTIGPACKS+  LH M+S+GMNVARLNFSHGT+EYH ETI LVREA++TFKP+ RPIAIALDTKGPEIRTGL+ GS T E++L  G  I+IV D+ ++E+C+   LW+DY NI NIL++ + IYIDDGLISL+V  KG D+L C+VENGGLLGSKKGVNLPGA+VDLPAVSEKDK+DL+FGVE NVD+VFASFIR+ +AI+EI+ ILGE+GKHILII+KIEN EG+++ DEI+E +DGIMVARGD+GIEIP +KVV+AQKMMI +CN+ GKPVICATQMLESM++KP PT+AEISDVANAVLDG+DCVMLSGE+AKG +P++AV+ MH +C+EAE + +Q+K+ + IK+      +   ++A+AAVEAAQ   A+AIIV+TTTG S+HLI+KYRP CPIL VTR+ + ARQ HLWRGLHP+    PR+ +W+ED+D RI  S+ YG++ G L+  D V+IVT WK   GSTNT+RI+ ++
Sbjct:   20 RITSNDYRSNLEHTSKLNYNDEPGVIRNSGIICTIGPACKSVTILHKMISAGMNVARLNFSHGTYEYHEETINLVREAVDTFKPYFRPIAIALDTKGPEIRTGLVNGSATGEVNLYKGSTIKIVVDNKYSEQCNSSQLWVDYVNIINILEVNSSIYIDDGLISLVVIKKGSDFLMCEVENGGLLGSKKGVNLPGAKVDLPAVSEKDKEDLRFGVEHNVDMVFASFIRSGNAIKEIKDILGEKGKHILIISKIENLEGVQKFDEILEISDGIMVARGDLGIEIPPEKVVLAQKMMIGRCNRAGKPVICATQMLESMINKPTPTKAEISDVANAVLDGADCVMLSGETAKGQYPLEAVQVMHSICREAENVLYQSKFFEAIKHTISGPTDQTHSTAVAAVEAAQRCHAAAIIVITTTGRSAHLIAKYRPTCPILTVTRHPITARQSHLWRGLHPIFYNEPRMIDWTEDMDERIHYSLSYGFRRGFLQMNDFVIIVTGWKAGVGSTNTLRIIRIE 531
[Close]
BLAST of Pyruvate kinase vs. Planmine SMEST
Match: SMESG000052083.1 (SMESG000052083.1)

HSP 1 Score: 694.115 bits (1790), Expect = 0.000e+0
Identity = 333/527 (63.19%), Postives = 426/527 (80.83%), Query Frame = 2 
Query:   65 MSTNSSSVEKSDSLTQ*R-IMKNKPDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSGMNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRTGLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIGNKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAVSEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKIENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQGKPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFPIQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHXXXXXXXXXXXXQLSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHPLLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGSTNTIRIV 1642
            M  N SS E ++   Q + + +      L  +C+ DID++P  VR++ IICTIGPAC+++ TL  M++SGMN+AR+NFSHG+HEYHAETIKLVREA+ETF P+ RP+A+ALDTKGPEIRTGLI GSGT E+ LV G +I++V D+ +A+ C+E+ LW+DYKNI  IL  G +IY+DDGLISLIV   GKDYLDC+VENGG LGSKKGVNLPGA+VDLPAVS+KD  DL FGVEQ VD+VFASFIR   A+ EIR+ILGE+GKHILII+KIENHEG+KR DEI++ +DGIMVARGD+GIEIPA+KV +AQKMMI +CN+ GKP+ICATQMLESM++KPRPTRAE SDVANA+LDG+DCVMLSGE+AKG++P++AV+ MH +C+EAE+  FQ K+ +++K       +   ++AIAAVEAAQ  +ASAI+V+TTTG S++LIS+YRPRCPIL VTR+ V ARQ HLWRG+HPLL +  RLD W+ D+D RI+ +  Y  + G +K GD V++VT WK  SGSTNT+R++
Sbjct:    1 MKKNPSSFEINNYFIQNQNVHRGVSRSHLEFICNLDIDNEPDVVRSSSIICTIGPACRTVSTLKKMIASGMNIARMNFSHGSHEYHAETIKLVREAVETFTPYYRPVALALDTKGPEIRTGLIHGSGTGEVTLVKGNKIKLVIDEKYADSCNEEILWVDYKNIVKILHKGCRIYVDDGLISLIVVETGKDYLDCEVENGGNLGSKKGVNLPGAKVDLPAVSDKDISDLHFGVEQGVDMVFASFIRCGAAVDEIRAILGEKGKHILIISKIENHEGVKRFDEILQASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRLGKPIICATQMLESMITKPRPTRAESSDVANAILDGADCVMLSGETAKGAYPLEAVQIMHHICREAESAVFQGKFFEDLKGEIVGSTDQTHSTAIAAVEAAQRCRASAIVVVTTTGRSAYLISRYRPRCPILTVTRHPVTARQGHLWRGVHPLLYDAKRLDEWTTDMDNRINWAFGYAMRRGFVKNGDYVIVVTGWKAGSGSTNTMRVI 527
The following BLAST results are available for this feature:
BLAST of Pyruvate kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PKM0.000e+062.33pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:... [more]
PKM0.000e+062.33pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:... [more]
PKM0.000e+062.33pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:... [more]
PKM0.000e+062.33pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:... [more]
PKM0.000e+061.93pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of Pyruvate kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pyk-10.000e+058.57Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL... [more]
pyk-10.000e+058.57Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL... [more]
pyk-10.000e+058.57Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL... [more]
pyk-10.000e+058.57Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL... [more]
pyk-10.000e+058.57Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:Q7JL... [more]
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BLAST of Pyruvate kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PyK0.000e+059.45gene:FBgn0267385 transcript:FBtr0084213[more]
PyK0.000e+059.45gene:FBgn0267385 transcript:FBtr0084214[more]
CG70691.342e-14353.40gene:FBgn0038952 transcript:FBtr0084215[more]
CG29642.854e-13842.43gene:FBgn0031462 transcript:FBtr0077722[more]
CG73623.949e-7349.26gene:FBgn0038258 transcript:FBtr0331700[more]
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BLAST of Pyruvate kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkma0.000e+061.34pyruvate kinase M1/2a [Source:ZFIN;Acc:ZDB-GENE-03... [more]
pkma0.000e+061.34pyruvate kinase M1/2a [Source:ZFIN;Acc:ZDB-GENE-03... [more]
pkma0.000e+061.54pyruvate kinase M1/2a [Source:ZFIN;Acc:ZDB-GENE-03... [more]
pkmb0.000e+061.14pyruvate kinase M1/2b [Source:ZFIN;Acc:ZDB-GENE-04... [more]
pkmb0.000e+061.14pyruvate kinase M1/2b [Source:ZFIN;Acc:ZDB-GENE-04... [more]
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BLAST of Pyruvate kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkm0.000e+061.54pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224][more]
pkm0.000e+061.54pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224][more]
pkm0.000e+061.54pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224][more]
pkm0.000e+061.54pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224][more]
pkm0.000e+061.54pyruvate kinase M1/2 [Source:NCBI gene;Acc:549224][more]
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BLAST of Pyruvate kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pkm0.000e+062.13pyruvate kinase, muscle [Source:MGI Symbol;Acc:MGI... [more]
Pkm0.000e+061.93pyruvate kinase, muscle [Source:MGI Symbol;Acc:MGI... [more]
Pklr0.000e+055.62pyruvate kinase liver and red blood cell [Source:M... [more]
Pklr0.000e+055.62pyruvate kinase liver and red blood cell [Source:M... [more]
Pkm7.345e-9767.94pyruvate kinase, muscle [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Pyruvate kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P00548|KPYM_CHICK0.000e+061.57Pyruvate kinase PKM OS=Gallus gallus OX=9031 GN=PK... [more]
sp|P11974|KPYM_RABIT0.000e+061.93Pyruvate kinase PKM OS=Oryctolagus cuniculus OX=99... [more]
sp|Q5NVN0|KPYM_PONAB0.000e+062.13Pyruvate kinase PKM OS=Pongo abelii OX=9601 GN=PKM... [more]
sp|P11980|KPYM_RAT0.000e+062.13Pyruvate kinase PKM OS=Rattus norvegicus OX=10116 ... [more]
sp|P11979|KPYM_FELCA0.000e+061.93Pyruvate kinase PKM OS=Felis catus OX=9685 GN=PKM ... [more]
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BLAST of Pyruvate kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267EYV50.000e+063.67Pyruvate kinase (Fragment) OS=Macrostomum lignano ... [more]
A0A267F2740.000e+064.87Pyruvate kinase OS=Macrostomum lignano OX=282301 G... [more]
A0A3Q2DAM80.000e+062.92Pyruvate kinase OS=Cyprinodon variegatus OX=28743 ... [more]
A0A3Q2EDH10.000e+062.92Pyruvate kinase OS=Cyprinodon variegatus OX=28743 ... [more]
A0A3Q2DAL90.000e+062.92Pyruvate kinase OS=Cyprinodon variegatus OX=28743 ... [more]
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BLAST of Pyruvate kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkma0.000e+062.13pyruvate kinase PKM [Source:NCBI gene;Acc:10304421... [more]
pkma0.000e+062.13pyruvate kinase PKM [Source:NCBI gene;Acc:10304421... [more]
pkma0.000e+062.13pyruvate kinase PKM [Source:NCBI gene;Acc:10304421... [more]
pkma0.000e+062.13pyruvate kinase PKM [Source:NCBI gene;Acc:10304421... [more]
pkmb0.000e+061.54pyruvate kinase PKM-like [Source:NCBI gene;Acc:103... [more]
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BLAST of Pyruvate kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pkma0.000e+057.17pyruvate kinase M1/2a [Source:ZFIN;Acc:ZDB-GENE-03... [more]
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BLAST of Pyruvate kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
CDC192.131e-15849.39Pyruvate kinase; functions as a homotetramer in gl... [more]
PYK22.269e-14745.45Pyruvate kinase; appears to be modulated by phosph... [more]
YAL037C-B_mRNA4.377e-2426.69Dubious open reading frame; unlikely to encode a f... [more]
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BLAST of Pyruvate kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO499630.000e+053.64Pyruvate kinase [Source:UniProtKB/TrEMBL;Acc:A7RE... [more]
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BLAST of Pyruvate kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkma0.000e+062.92pyruvate kinase PKM [Source:NCBI gene;Acc:10117074... [more]
pkma0.000e+062.33pyruvate kinase PKM [Source:NCBI gene;Acc:10117074... [more]
pkma0.000e+062.33pyruvate kinase PKM [Source:NCBI gene;Acc:10117074... [more]
pkmb0.000e+060.55pyruvate kinase PKM [Source:NCBI gene;Acc:10117042... [more]
pklr0.000e+053.16pyruvate kinase PKM [Source:NCBI gene;Acc:10116118... [more]
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BLAST of Pyruvate kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000006009.10.000e+099.05SMESG000006009.1[more]
SMESG000006014.10.000e+098.68SMESG000006014.1[more]
SMESG000068454.10.000e+073.90SMESG000068454.1[more]
SMESG000017675.10.000e+064.06SMESG000017675.1[more]
SMESG000052083.10.000e+063.19SMESG000052083.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006660 ID=SMED30006660|Name=Pyruvate kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1716bp
GTTAGTTTCAAAGTTTTATCGAATTTTATTTGACACTATTATATAAATTT
TACAAATTCTAAAAATGTCTACGAATTCTTCGTCCGTTGAAAAATCCGAT
TCTCTTACTCAATAGAGAATTATGAAAAACAAACCGGATTGCGTTTTGAG
TCATTTATGTGATCGCGATATTGACAGTGATCCAGGATCAGTGAGAAACA
CTGGAATCATCTGCACAATCGGACCGGCGTGCAAAAGCATCAAAACTCTC
CATGGAATGATGAGTTCTGGAATGAATGTCGCAAGACTGAATTTCAGTCA
TGGAACTCATGAATATCACGCAGAGACCATTAAATTAGTTCGTGAAGCTA
TTGAAACTTTCAAGCCACACCGAAGACCAATTGCAATTGCATTGGATACA
AAGGGACCAGAAATTAGAACAGGTCTCATAAGAGGAAGTGGAACTGCCGA
AATTCATTTGGTTGATGGCCAACAAATTCGAATAGTTACTGATGACATCT
TTGCGGAGAAATGTGATGAAAAGAATCTTTGGTTGGATTACAAAAATATT
ACAAACATTCTTGACATTGGAAACAAAATTTATATCGATGATGGCCTTAT
TAGTTTGATTGTTCAAGCCAAGGGGAAAGATTATCTGGATTGTAAAGTAG
AAAATGGAGGTTTGTTGGGTTCGAAAAAAGGTGTTAATCTTCCAGGAGCC
CAAGTCGATTTACCCGCGGTCTCTGAAAAAGATAAACAAGATTTAAAATT
CGGTGTCGAACAAAATGTTGACATTGTTTTCGCTTCTTTCATTCGAAATG
CAGATGCTATTCGAGAAATTCGATCAATTCTCGGAGAAGAAGGAAAACAT
ATTCTCATTATTGCTAAAATTGAAAACCATGAAGGTATCAAACGAATTGA
TGAAATCATCGAAGAAGCCGACGGAATAATGGTTGCAAGAGGTGACATGG
GAATCGAAATTCCTGCTCAGAAAGTAGTTGTTGCTCAGAAAATGATGATT
GCAAAATGCAATAAACAAGGAAAGCCTGTCATTTGTGCTACCCAGATGCT
CGAATCTATGGTTTCTAAACCCAGACCGACTAGAGCAGAAATTAGTGATG
TCGCCAATGCCGTTTTAGATGGAAGTGATTGTGTCATGTTATCTGGAGAA
TCAGCTAAAGGCTCCTTTCCGATCCAAGCAGTTAAAACCATGCACGAAGT
ATGTAAAGAAGCTGAAGCAATTTTCTTTCAAAATAAATATCTTCAAGAAA
TAAAGAATGTGAATCGACATTTCAACAACCATGTAGAAGCATCAGCAATT
GCTGCAGTTGAAGCTGCACAGTTGTCTAAAGCTTCAGCGATTATTGTGTT
GACAACGACCGGAAATTCTTCACATTTAATTTCTAAATATCGCCCTCGTT
GTCCAATTCTTGCAGTGACTCGAAATGAAGTCGTTGCAAGACAATGCCAT
TTGTGGAGGGGACTCCATCCATTACTAGTTGAGTTTCCTCGACTGGATAA
TTGGAGTGAAGATGTCGATGCAAGAATAGATTGCTCTATCCAATACGGAT
ACAAATCCGGAATTTTGAAGAAAGGAGATTCTGTTGTCATAGTAACGATA
TGGAAACCGGTTTCCGGATCTACAAATACCATTAGAATTGTAAATGTCGA
TTAGAAAGGAATTTCTCTGATTTTCATTTGATATTGAAATATATTTTTGC
ACGATTTGAAAAAAAA
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protein sequence of SMED30006660-orf-1

>SMED30006660-orf-1 ID=SMED30006660-orf-1|Name=SMED30006660-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=511bp
MKNKPDCVLSHLCDRDIDSDPGSVRNTGIICTIGPACKSIKTLHGMMSSG
MNVARLNFSHGTHEYHAETIKLVREAIETFKPHRRPIAIALDTKGPEIRT
GLIRGSGTAEIHLVDGQQIRIVTDDIFAEKCDEKNLWLDYKNITNILDIG
NKIYIDDGLISLIVQAKGKDYLDCKVENGGLLGSKKGVNLPGAQVDLPAV
SEKDKQDLKFGVEQNVDIVFASFIRNADAIREIRSILGEEGKHILIIAKI
ENHEGIKRIDEIIEEADGIMVARGDMGIEIPAQKVVVAQKMMIAKCNKQG
KPVICATQMLESMVSKPRPTRAEISDVANAVLDGSDCVMLSGESAKGSFP
IQAVKTMHEVCKEAEAIFFQNKYLQEIKNVNRHFNNHVEASAIAAVEAAQ
LSKASAIIVLTTTGNSSHLISKYRPRCPILAVTRNEVVARQCHLWRGLHP
LLVEFPRLDNWSEDVDARIDCSIQYGYKSGILKKGDSVVIVTIWKPVSGS
TNTIRIVNVD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR001697Pyr_Knase
IPR015794Pyrv_Knase_a/b
IPR015813Pyrv/PenolPyrv_Kinase-like_dom
IPR015795Pyrv_Knase_C
IPR015793Pyrv_Knase_brl
IPR015806Pyrv_Knase_insert_dom_sf
IPR018209Pyrv_Knase_AS
IPR011037Pyrv_Knase-like_insert_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006096glycolytic process
GO:0016310phosphorylation
Vocabulary: molecular function
TermDefinition
GO:0004743pyruvate kinase activity
GO:0030955potassium ion binding
GO:0000287magnesium ion binding
GO:0003824catalytic activity
GO:0016301kinase activity
GO:0016740transferase activity