WW domain-containing oxidoreductase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30006610 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of WW domain-containing oxidoreductase vs. Ensembl Human
Match: WWOX (WW domain containing oxidoreductase [Source:HGNC Symbol;Acc:HGNC:12799]) HSP 1 Score: 105.916 bits (263), Expect = 3.944e-31 Identity = 67/220 (30.45%), Postives = 112/220 (50.91%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYLTTKINQIKIVNQ 1187
+ ++V +A + P+S+++DG ET+FQVN L FY+ ++L L RV+ +S ESHR ++ +L+ L+P+ +Y +Y S LC IL + +L + + HPGN++Y ++I R + +F PFTK++ Q AAT + C + G YFNN C C P+ QS+ LW L+ ++ Q ++ +Q
Sbjct: 204 LHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLC---RSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-SNIHRSWWVYTLLFTLARPFTKSMQQGAATTVYCAAVPELEGLGGMYFNNCCRCMPSPEAQSEETARTLW-ALSERLIQERLGSQ 412 HSP 2 Score: 50.8322 bits (120), Expect = 3.944e-31 Identity = 37/164 (22.56%), Postives = 66/164 (40.24%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIKIH-KSDVCY---EKIRYNKSCGFRPPKERHKRFI------------------QKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTK 541
DT+SE ELPPGW ++ +G + Y NH +Q P + D+ Y ++ N F + ++ Q++D +T+ +++ + + K +V G SGIG E +IL C N+ + + L ++ K
Sbjct: 11 DTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHK 174
BLAST of WW domain-containing oxidoreductase vs. Ensembl Human
Match: WWOX (WW domain containing oxidoreductase [Source:HGNC Symbol;Acc:HGNC:12799]) HSP 1 Score: 70.4774 bits (171), Expect = 1.475e-20 Identity = 47/159 (29.56%), Postives = 82/159 (51.57%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTL 1004
+ ++V +A + P+S+++DG ET+FQVN L FY+ ++L L RV+ +S ESHR ++ +L+ L+P+ +Y +Y S LC IL + +L + + HPGN++Y ++I R + +F PFTK++
Sbjct: 204 LHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLC---RSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-SNIHRSWWVYTLLFTLARPFTKSM 352 HSP 2 Score: 50.8322 bits (120), Expect = 1.475e-20 Identity = 37/164 (22.56%), Postives = 66/164 (40.24%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIKIH-KSDVCY---EKIRYNKSCGFRPPKERHKRFI------------------QKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTK 541
DT+SE ELPPGW ++ +G + Y NH +Q P + D+ Y ++ N F + ++ Q++D +T+ +++ + + K +V G SGIG E +IL C N+ + + L ++ K
Sbjct: 11 DTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHK 174
BLAST of WW domain-containing oxidoreductase vs. Ensembl Human
Match: WWOX (WW domain containing oxidoreductase [Source:HGNC Symbol;Acc:HGNC:12799]) HSP 1 Score: 68.5514 bits (166), Expect = 1.017e-12 Identity = 47/159 (29.56%), Postives = 82/159 (51.57%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTL 1004
+ ++V +A + P+S+++DG ET+FQVN L FY+ ++L L RV+ +S ESHR ++ +L+ L+P+ +Y +Y S LC IL + +L + + HPGN++Y ++I R + +F PFTK++
Sbjct: 2 LHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLC---RSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-SNIHRSWWVYTLLFTLARPFTKSM 150
BLAST of WW domain-containing oxidoreductase vs. Ensembl Human
Match: WDR91 (WD repeat domain 91 [Source:HGNC Symbol;Acc:HGNC:24997]) HSP 1 Score: 73.9442 bits (180), Expect = 1.259e-12 Identity = 77/344 (22.38%), Postives = 147/344 (42.73%), Query Frame = 1
Query: 2503 FHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXXXALPH----------GVISLYDAESWSAIQTNLITLKSDFTVNCMY--CSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSK----SIPKESSHLNDFVIPLSWAEKP-----YGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKING-TTLLDSVYLNAGHNSPVICID 3468
+ EH S + H + S ASLDV G K+W+ N P ++ + K + S +W ++ ++LLG+ G+V++YD + + E+ I+ PRI + + + FVC + S ++ + + P G + L+D ++ Q +NC + N + G ++G I+L D++ E C W R+++ Y + S ++ + K +I K ++++ +P S A P Y G + + PR L A+ + N + + + G ++ K+ G +L+S GH +PV+ +D
Sbjct: 404 YGEHHSSIMHCRVD-CSGRRVASLDVDGVIKVWSFN-PIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSKGMNQVPGRLLLWDTKTMKQ-QLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHE---------------------CAMSW-RAHYGEVYSVEFSYDEN-TVYSIGEDGKFIQWNIHKSGLKVSEYSLP-SDATGPFVLSGYSGYKQVQVPRGRLF--AFDSEGNYMLTCSATGGVIYKLGGDEKVLESCLSLGGHRAPVVTVD 718 HSP 2 Score: 71.633 bits (174), Expect = 6.772e-12 Identity = 41/141 (29.08%), Postives = 67/141 (47.52%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKK-KSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
+++ L + + +TL E K D+ K + VD LQ +Q DL +L W E F L+ + T +K+ +F+ +LV + + +K FF T L ++ EW DWF P + +P + F YF+R W
Sbjct: 12 VREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAALRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATE-LQNQAEWKDWFVLPFLPSPDTNPTFATYFSRQW 151
BLAST of WW domain-containing oxidoreductase vs. Ensembl Human
Match: WDR91 (WD repeat domain 91 [Source:HGNC Symbol;Acc:HGNC:24997]) HSP 1 Score: 73.559 bits (179), Expect = 1.599e-12 Identity = 82/367 (22.34%), Postives = 155/367 (42.23%), Query Frame = 1
Query: 2503 FHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXXXALPH----------GVISLYDAESWSAIQTNLITLKSDFTVNCMY--CSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSK----SIPKESSHLNDFVIPLSWAEKP-----YGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKING-TTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTI 3537
+ EH S + H + S ASLDV G K+W+ N P ++ + K + S +W ++ ++LLG+ G+V++YD + + E+ I+ PRI + + + FVC + S ++ + + P G + L+D ++ Q +NC + N + G ++G I+L D++ E C W R+++ Y + S ++ + K +I K ++++ +P S A P Y G + + PR L A+ + N + + + G ++ K+ G +L+S GH +PV+ +D D L+ +M+G I
Sbjct: 369 YGEHHSSIMHCRVD-CSGRRVASLDVDGVIKVWSFN-PIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDNMPRILSLACSPNGASFVCSAAAPSLTSQVDFSAPDIGSKGMNQVPGRLLLWDTKTMKQ-QLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHE---------------------CAMSW-RAHYGEVYSVEFSYDEN-TVYSIGEDGKFIQWNIHKSGLKVSEYSLP-SDATGPFVLSGYSGYKQVQVPRGRLF--AFDSEGNYMLTCSATGGVIYKLGGDEKVLESCLSLGGHRAPVVTVDWS----TAMDCGTCLTASMDGKI 702 HSP 2 Score: 66.2402 bits (160), Expect = 3.420e-10 Identity = 34/107 (31.78%), Postives = 52/107 (48.60%), Query Frame = 1
Query: 1456 VDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
VD LQ +Q DL +L W E F L+ + T +K+ +F+ +LV + + +K FF T L ++ EW DWF P + +P + F YF+R W
Sbjct: 11 VDQLQQLMQVYDLAALRDYWSYLERRLFSRLEDIYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATE-LQNQAEWKDWFVLPFLPSPDTNPTFATYFSRQW 116
BLAST of WW domain-containing oxidoreductase vs. Ensembl Celegans
Match: sorf-1 (Suppressor of organelle fusion 1 [Source:UniProtKB/Swiss-Prot;Acc:Q23533]) HSP 1 Score: 73.9442 bits (180), Expect = 3.554e-14 Identity = 41/144 (28.47%), Postives = 72/144 (50.00%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKKKSRY----FVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
++ L+ K +L +F +E K++ Y +D + +AI +D+D+L +W+ + F LD + K A ++ ++ FLV C + K K N FF+ M + L + +WADWF FP + + + F YF + W
Sbjct: 12 VRNYLAAKSMVTSLKAFDQESSF---AKEANYQVDRCIDEMTDAIDKHDVDTLCAMWESWNARVFHSLDTEGIKQAQCYEASAYRLFLVRCVQKKNISKCNEFFRKMSSLTLNNP-QWADWFAFPYNHHAKDTEPFRKYFDKTW 151
BLAST of WW domain-containing oxidoreductase vs. Ensembl Celegans
Match: sorf-1 (Suppressor of organelle fusion 1 [Source:UniProtKB/Swiss-Prot;Acc:Q23533]) HSP 1 Score: 73.9442 bits (180), Expect = 3.554e-14 Identity = 41/144 (28.47%), Postives = 72/144 (50.00%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKKKSRY----FVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
++ L+ K +L +F +E K++ Y +D + +AI +D+D+L +W+ + F LD + K A ++ ++ FLV C + K K N FF+ M + L + +WADWF FP + + + F YF + W
Sbjct: 12 VRNYLAAKSMVTSLKAFDQESSF---AKEANYQVDRCIDEMTDAIDKHDVDTLCAMWESWNARVFHSLDTEGIKQAQCYEASAYRLFLVRCVQKKNISKCNEFFRKMSSLTLNNP-QWADWFAFPYNHHAKDTEPFRKYFDKTW 151
BLAST of WW domain-containing oxidoreductase vs. Ensembl Celegans
Match: E04F6.15 (pep chromosome:WBcel235:II:7208773:7210287:-1 gene:WBGene00017131.1 transcript:E04F6.15.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:E04F6.15) HSP 1 Score: 60.4622 bits (145), Expect = 7.406e-13 Identity = 57/211 (27.01%), Postives = 89/211 (42.18%), Query Frame = 3
Query: 561 IVFSAGIMSPPFSVSEDGFETSFQVNVLSLF-YIQEML-------------LSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYL 1151
++ +AG+ P + DGFE F +N L+ F I+E+L ++S+ S H VK R +++L+ ++Q Y F YA S +C IL + K + + + HPG+ V T + R + + PFTK SQ AAT + C + K SG Y+ + C D L + E L L
Sbjct: 111 LILNAGVFGPSEKTTSDGFEAHFGINHLAHFILIKELLPVLRESAPSRIVIVTSMLSKHTCVK--------PDSRIVEKLDTLCPKEATQWY--FRLYAKSKMCNIL----TAFKLHRDEFKNRISVYAVHPGSGV-RTDLHRDFGLWSIADFLSIPFTKNASQGAATSLYCAVHPEVKELSGKYWES-CWDDEKNLDKKVSRDEELQEAL 305 HSP 2 Score: 33.4982 bits (75), Expect = 7.406e-13 Identity = 19/67 (28.36%), Postives = 35/67 (52.24%), Query Frame = 2
Query: 332 QKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVD 532
++F S + + +V++ +LS K + G SGIG+E LI K +++ N + KS L++
Sbjct: 9 RQFHSRTNALEVLDGIDLSGKTFAITGTTSGIGVETAKALILKGAHVVMINRNYTASEASKKSLLIE 75
BLAST of WW domain-containing oxidoreductase vs. Ensembl Celegans
Match: dhs-8 (DeHydrogenases, Short chain [Source:UniProtKB/TrEMBL;Acc:U4PLQ0]) HSP 1 Score: 67.3958 bits (163), Expect = 7.427e-12 Identity = 59/215 (27.44%), Postives = 92/215 (42.79%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSC---ESHRAIKELNLCE----LNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCIC-DPTLLGQSKINGEMLWNYLTTKINQI 1172
I ++ +AG+ P + ++DGFE+ + VNV++ F + +LL + RVV+LS H K + + E L + Y S + +LI K + + HPG+ V T I R + KFI + +PFTK SQ AAT + C + SG Y+ + C D + + E L L K+ QI
Sbjct: 51 IHGLILNAGVFRPAAAKTKDGFESHYGVNVVAHFTLLRILLPVV---RRSAPSRVVFLSSTLSSKHGFKKSMGISEKMSILQGEDSSASTLQMYGASKMADMLIA----FKLHRDEYKNGISTYSVHPGSGV-RTDIFRNSLLGKFIGFVTTPFTKNASQGAATTVYCATHPEVEKISGKYWES---CWDNDKIDKKTARDEELQEALWKKLEQI 254
BLAST of WW domain-containing oxidoreductase vs. Ensembl Celegans
Match: dhs-8 (DeHydrogenases, Short chain [Source:UniProtKB/TrEMBL;Acc:U4PLQ0]) HSP 1 Score: 67.781 bits (164), Expect = 1.326e-11 Identity = 59/215 (27.44%), Postives = 92/215 (42.79%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSC---ESHRAIKELNLCE----LNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCIC-DPTLLGQSKINGEMLWNYLTTKINQI 1172
I ++ +AG+ P + ++DGFE+ + VNV++ F + +LL + RVV+LS H K + + E L + Y S + +LI K + + HPG+ V T I R + KFI + +PFTK SQ AAT + C + SG Y+ + C D + + E L L K+ QI
Sbjct: 107 IHGLILNAGVFRPAAAKTKDGFESHYGVNVVAHFTLLRILLPVV---RRSAPSRVVFLSSTLSSKHGFKKSMGISEKMSILQGEDSSASTLQMYGASKMADMLIA----FKLHRDEYKNGISTYSVHPGSGV-RTDIFRNSLLGKFIGFVTTPFTKNASQGAATTVYCATHPEVEKISGKYWES---CWDNDKIDKKTARDEELQEALWKKLEQI 310
BLAST of WW domain-containing oxidoreductase vs. Ensembl Fly
Match: Wwox (gene:FBgn0031972 transcript:FBtr0079550) HSP 1 Score: 120.939 bits (302), Expect = 9.330e-29 Identity = 71/206 (34.47%), Postives = 110/206 (53.40%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR----AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLW 1142
Q ID ++ +AG+ + P++ + DG ET+FQV+ LS FY+ + L +LF K R++ LS ESHR ++ L + L+P ++Y +Y + LC +L + +W R F HPGN+V ++ ++R + +F PFTK+L QAAAT I C +N SG YFNN C+P+ L +S + LW
Sbjct: 198 QSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLT-LQLETLFD----YKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWK----QRGISVFSLHPGNMV-SSDLSRNYWFYRLLFAIVRPFTKSLQQAAATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLW 393
BLAST of WW domain-containing oxidoreductase vs. Ensembl Fly
Match: Wwox (gene:FBgn0031972 transcript:FBtr0343384) HSP 1 Score: 120.939 bits (302), Expect = 9.330e-29 Identity = 71/206 (34.47%), Postives = 110/206 (53.40%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR----AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLW 1142
Q ID ++ +AG+ + P++ + DG ET+FQV+ LS FY+ + L +LF K R++ LS ESHR ++ L + L+P ++Y +Y + LC +L + +W R F HPGN+V ++ ++R + +F PFTK+L QAAAT I C +N SG YFNN C+P+ L +S + LW
Sbjct: 198 QSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLT-LQLETLFD----YKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWK----QRGISVFSLHPGNMV-SSDLSRNYWFYRLLFAIVRPFTKSLQQAAATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLW 393
BLAST of WW domain-containing oxidoreductase vs. Ensembl Fly
Match: CG6005 (gene:FBgn0038672 transcript:FBtr0343992) HSP 1 Score: 70.8626 bits (172), Expect = 1.574e-12 Identity = 36/141 (25.53%), Postives = 73/141 (51.77%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKK-KSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
+++ L + + +TL + E++ ++ + ++ ++ NA+Q +DL +L +W + F L+ +++ + K +LV + + + EKV+ FF + L ++EW DWF FP KN E F ++FT+ W
Sbjct: 11 LREYLVFRGFSSTLKALDLEQRTEKDQHFRAERILEQFNNAVQASDLQALRSLWFHLDNNIFSKLEHTYAVAVKKLENSLLKYYLVTAYSSNRPEKVSEFFNKLAG-DLQQQSEWKDWFYFPFCKNAEESPTFALFFTKQW 150
BLAST of WW domain-containing oxidoreductase vs. Ensembl Fly
Match: CG6005 (gene:FBgn0038672 transcript:FBtr0083719) HSP 1 Score: 70.8626 bits (172), Expect = 1.574e-12 Identity = 36/141 (25.53%), Postives = 73/141 (51.77%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKK-KSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
+++ L + + +TL + E++ ++ + ++ ++ NA+Q +DL +L +W + F L+ +++ + K +LV + + + EKV+ FF + L ++EW DWF FP KN E F ++FT+ W
Sbjct: 11 LREYLVFRGFSSTLKALDLEQRTEKDQHFRAERILEQFNNAVQASDLQALRSLWFHLDNNIFSKLEHTYAVAVKKLENSLLKYYLVTAYSSNRPEKVSEFFNKLAG-DLQQQSEWKDWFYFPFCKNAEESPTFALFFTKQW 150
BLAST of WW domain-containing oxidoreductase vs. Ensembl Fly
Match: CG11200 (gene:FBgn0034500 transcript:FBtr0086299) HSP 1 Score: 63.929 bits (154), Expect = 3.518e-10 Identity = 54/188 (28.72%), Postives = 94/188 (50.00%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSP-HNGVKCRVVWL-SCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNV---VYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNG 1085
+++ ++DL++ +AGIM PF ++ DG+E+ F +N L F + +LL L + G R+V + SC + I +N ++N + Y G +Y+ S L +IL ++ + D+ + V HPG V ++ S T PI K +F+ KT + + T + I S + G Y +NG
Sbjct: 143 ERYSKVDLLLNNAGIMFAPFKLTADGYESHFAINFLGHFLLTHLLLPQLRAAGKEGRNSRIVNVSSCVN--LIGRINYKDINGTKHYYPG-TAYSQSKLAQILFTRHLQTLLDAEKSHVQ--VNVVHPGIVDTDLFEHSATTSVPIFKKLFF------KTPERGSRTVVFAAIDPSIEGQGGTYLSNG 319
BLAST of WW domain-containing oxidoreductase vs. Ensembl Zebrafish
Match: wdr91 (WD repeat domain 91 [Source:NCBI gene;Acc:402898]) HSP 1 Score: 85.5001 bits (210), Expect = 2.052e-16 Identity = 89/352 (25.28%), Postives = 153/352 (43.47%), Query Frame = 1
Query: 2503 FHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXX----XALPHGVISLYDAESWSAIQTNLITLKSDFTVNCMY--CSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKIN-GTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTI 3537
+ EH S + H + S ASLDV G K+WA N P ++ T+ K + S +W ++ ++LLG+ G+VK+YD + + EM ID PRI + S + FVC + S + + SA G + L+D ++ Q +NC + N + G ++G I+L D++ E + S +G EV +V ++D N + + + +++ E S D V P + Y G + + PR L A+ + + + + G + ++N L+SV AGH +PV+ +D D L+ +M+G I
Sbjct: 390 YGEHHSSIMHCRVD-CSGRRVASLDVDGVVKVWAFN-PIMQTKATIMSKSPLLSLEWAAKPDRLLLLGSGVGTVKLYDTDAKKCLYEMTIDDVHPRILSLACSPSGTSFVCSAAAHSGAVMESEPRGSAPVSGQLLLWDTKTVKQ-QLQFALEPGPVAINCTAFNHNGNLLVTGAADGIIRLFDMQRYE--SALSWKAHDG-EVYSV---------EFSYDENTVFSIGEDGKFVQWNIHRCGVK-QSEYSLSQDAVGPFVLSG--YSGYKQVQVPRGRLF--AFDSEGQHVLTCSSTGGNIYRLNKAEAGLESVLSLAGHKAPVVTVDW----CSAMDCGTCLTASMDGKI 717 HSP 2 Score: 70.8626 bits (172), Expect = 7.122e-12 Identity = 40/141 (28.37%), Postives = 68/141 (48.23%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKK-KSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
+++ L + + +TL E K D+ K + +D LQ IQ+ DL L + W E F L+ + T +++ +++ +L+ + K EK FFQ L ++ EW DWF P + P ++ F YF+R W
Sbjct: 15 VREYLIYRGFTSTLKHLDSEIKTDKEKGFRVDKIMDQLQLLIQSCDLTGLKEYWANLERRLFCRLEDVYKPTVSKLRTSLYRFYLIHTVQVKNVEKTQEFFQKQA-LELQAQAEWRDWFSLPFIPAPEQNPSFSAYFSRQW 154
BLAST of WW domain-containing oxidoreductase vs. Ensembl Zebrafish
Match: wdr91 (WD repeat domain 91 [Source:NCBI gene;Acc:402898]) HSP 1 Score: 85.5001 bits (210), Expect = 2.087e-16 Identity = 89/352 (25.28%), Postives = 153/352 (43.47%), Query Frame = 1
Query: 2503 FHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXX----XALPHGVISLYDAESWSAIQTNLITLKSDFTVNCMY--CSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKIN-GTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTI 3537
+ EH S + H + S ASLDV G K+WA N P ++ T+ K + S +W ++ ++LLG+ G+VK+YD + + EM ID PRI + S + FVC + S + + SA G + L+D ++ Q +NC + N + G ++G I+L D++ E + S +G EV +V ++D N + + + +++ E S D V P + Y G + + PR L A+ + + + + G + ++N L+SV AGH +PV+ +D D L+ +M+G I
Sbjct: 390 YGEHHSSIMHCRVD-CSGRRVASLDVDGVVKVWAFN-PIMQTKATIMSKSPLLSLEWAAKPDRLLLLGSGVGTVKLYDTDAKKCLYEMTIDDVHPRILSLACSPSGTSFVCSAAAHSGAVMESEPRGSAPVSGQLLLWDTKTVKQ-QLQFALEPGPVAINCTAFNHNGNLLVTGAADGIIRLFDMQRYE--SALSWKAHDG-EVYSV---------EFSYDENTVFSIGEDGKFVQWNIHRCGVK-QSEYSLSQDAVGPFVLSG--YSGYKQVQVPRGRLF--AFDSEGQHVLTCSSTGGNIYRLNKAEAGLESVLSLAGHKAPVVTVDW----CSAMDCGTCLTASMDGKI 717 HSP 2 Score: 70.8626 bits (172), Expect = 7.183e-12 Identity = 40/141 (28.37%), Postives = 68/141 (48.23%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKK-KSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
+++ L + + +TL E K D+ K + +D LQ IQ+ DL L + W E F L+ + T +++ +++ +L+ + K EK FFQ L ++ EW DWF P + P ++ F YF+R W
Sbjct: 15 VREYLIYRGFTSTLKHLDSEIKTDKEKGFRVDKIMDQLQLLIQSCDLTGLKEYWANLERRLFCRLEDVYKPTVSKLRTSLYRFYLIHTVQVKNVEKTQEFFQKQA-LELQAQAEWRDWFSLPFIPAPEQNPSFSAYFSRQW 154
BLAST of WW domain-containing oxidoreductase vs. Ensembl Zebrafish
Match: si:dkey-94e7.2 (si:dkey-94e7.2 [Source:ZFIN;Acc:ZDB-GENE-070912-611]) HSP 1 Score: 73.559 bits (179), Expect = 8.019e-14 Identity = 59/205 (28.78%), Postives = 93/205 (45.37%), Query Frame = 3
Query: 546 REIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFW-FFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEM---LW 1142
R + L++ +AG+M P+S + DGFE F VN L F + + R++ LS +H + + L ++N S + Y+ +Y S L IL + KLK D + HPG + T + R+ + I W PFTKT Q A T I C + + SG Y+++ C P+ ++ + EM LW
Sbjct: 50 RSLHLLINNAGVMMCPYSKTADGFEMQFGVNHLGHFL---LTFLLIDLLKRSAPSRIINLSSMAH-SWGTITLDDIN-SERNYHSRRAYGQSKLANILFTRSLAKKLK------DTGVTSYAVHPG--IVRTELKRHMNLGLLIMWKVVRPFTKTPVQGAQTTIYCAVQPELDAESGGYYSD---CRPSRCTRAARDDEMAEKLW 238
BLAST of WW domain-containing oxidoreductase vs. Ensembl Zebrafish
Match: rdh12 (retinol dehydrogenase 12 [Source:ZFIN;Acc:ZDB-GENE-040718-9]) HSP 1 Score: 66.2402 bits (160), Expect = 1.000e-13 Identity = 54/212 (25.47%), Postives = 98/212 (46.23%), Query Frame = 3
Query: 537 QKF-REID---LIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLL---GQSKINGEMLWN 1145
Q+F RE+D +++ +AG+M P+ + DGFE VN L + + + R+V +S +H + +L+ S YN +Y S L +L + +L+ ++ + HPG V + + R+ ++ +F FFS F K+ + A T I C ++ +S SG +F++ C P + G+S+ LW+
Sbjct: 114 QRFLREVDHLHILINNAGVMMCPYMKTADGFEMQIGVNHLGHYL---LTYLLIGLLKRSAPSRIVVVSSLAHN-FGWIRFHDLH-SQGSYNSGLAYCQSKLANVLFTRELARRLQGSNVTVNS------VHPGTV--RSELVRHSTLMSLLFAFFSMFLKSPKEGAQTSIYCAVAEELQSISGKHFSD---CAPAFVAPQGRSEETARKLWD 309 HSP 2 Score: 31.5722 bits (70), Expect = 1.000e-13 Identity = 17/41 (41.46%), Postives = 22/41 (53.66%), Query Frame = 2
Query: 371 NTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNL 493
+T L K ALV G SGIG E L ++ +IL C +L
Sbjct: 37 STVRLDGKVALVTGANSGIGKETALDLASRGARVILACRDL 77
BLAST of WW domain-containing oxidoreductase vs. Ensembl Zebrafish
Match: si:dkey-94e7.2 (si:dkey-94e7.2 [Source:ZFIN;Acc:ZDB-GENE-070912-611]) HSP 1 Score: 73.1738 bits (178), Expect = 2.379e-13 Identity = 56/203 (27.59%), Postives = 91/203 (44.83%), Query Frame = 3
Query: 546 REIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFW-FFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEM---LW 1142
R + L++ +AG+M P+S + DGFE F VN L F + + R++ LS +H + + L ++N S + Y+ +Y S L IL + K + + HPG + T + R+ + I W PFTKT Q A T I C + + SG Y+++ C P+ ++ + EM LW
Sbjct: 94 RSLHLLINNAGVMMCPYSKTADGFEMQFGVNHLGHFL---LTFLLIDLLKRSAPSRIINLSSMAH-SWGTITLDDIN-SERNYHSRRAYGQSKLANILFTRSLAKKLKGVTS------YAVHPG--IVRTELKRHMNLGLLIMWKVVRPFTKTPVQGAQTTIYCAVQPELDAESGGYYSD---CRPSRCTRAARDDEMAEKLW 280
BLAST of WW domain-containing oxidoreductase vs. Ensembl Xenopus
Match: wdr91 (WD repeat domain 91 [Source:NCBI gene;Acc:780034]) HSP 1 Score: 126.331 bits (316), Expect = 6.540e-29 Identity = 174/754 (23.08%), Postives = 331/754 (43.90%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKKKS-RYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWXXXXXXXXXXXXXQV-----VRSVMSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNAGKSQIISQV---ISNLHGSGRTLHDVSDLLCDFRLTRENKQIEYRRASKSNKPKGI--SLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSN-QSSPNLADLDNS-VSMIE-----NSINSTVIGNIAPQASSEIN-KNSSAD---------------SFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXXXA-----------LPHGVISLYDAESW-SAIQTNLITLKSDFTVNCMYC--SSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKIN--GTTLLDSVYLNAGHNSPVICID 3468
+K+ L+ + + NTL F + K D+ K V+ L +Q+ DL+ L++ W E F L+ + T +K+ +F+ +LV ++ +T+K + FFQ T L ++ EW +WF P + P ++ F YF+R W D F +S+ NF + V ++++ SD + L + EN I + K + + Y L + ++ ++ +SN+ G S+L + + N + + S + G SL+ QNK K P + L + P + +V K + +A+ + +SSPN+ + + SM++ ++ A Q S+E +NS AD + G ++ +K +P + ++ + EH S + H + S ASLDV G KIW+++ +S K + S +W ++ ++LLG++ G+V++YD + + E+ I PRI + S + FVC + + + ++ +P G + L+D ++ +Q +L + VNC + N + G ++G I+L D++ ++ S G EV +V ++D N + + + +D+ + + E S +D P + Y G + + FPR L A+ + + + + G ++ K+N G+TL + + L GH +PV+ +D
Sbjct: 12 VKEYLTFRGFTNTLKYFEVDIKADKDKGFCVDRIVEQLLQFVQSYDLNGLVEYWAYLERRLFSRLEDVYRPTIHKLKTSLFRYYLVYTIQSSRTDKAHEFFQKQAT-ELQNQAEWKEWFALPFLPTPDSNRTFSTYFSRQWADTFTVSLHNFLSVLFQCMPVPKILTFQSDYQKIACL--QEENEI--MRQKLFALQAETYRLRKDGPSEPLVLHKLPHYVSNMDRLGD-----SELGSNIMSSHSNTNMN----TPSQRTSGFLSSLLAQNK-KPPPPKSTLPSVSSPTQSGGSVPLKKEVAVSQAQKAKELVGGTKEVRSSPNILGVPGTESSMVQQRHKRQQERKELLSKTASQVSTEKKAENSDADPDLRSDTQNDTVDAVTRGSGASGARKEEKPAQPFIVLSQDE-----YAEHHSSIMHCRVD-CSGRRVASLDVDGVIKIWSLDGIMQTKASAIS-KSALLSLEWATKRDRLLLLGSEVGTVRLYDTEAKKNLCEIGIVEDMPRILSLACSPSGASFVCSAAAATSPSQTDPTYYSYGESGNNQVP-GKLLLWDTKTMKQQLQFSLEPVP--IAVNCTAFNHNGNLLVTGAADGFIRLFDMQ--QHQCALSWKAHMG-EVYSVD---------FSYDENAVYSIGEDGKFIQWDIHKSGQKV-SEYSLPSDATGPFMLSG--YSGYKQVQFPRGRLF--AFDSEGKYMLTCSSTGGVIYKLNSDGSTLENCLSL-GGHRAPVVTVD 722
BLAST of WW domain-containing oxidoreductase vs. Ensembl Xenopus
Match: runx1 (RUNX family transcription factor 1 [Source:Xenbase;Acc:XB-GENE-483164]) HSP 1 Score: 58.9214 bits (141), Expect = 4.206e-18 Identity = 45/163 (27.61%), Postives = 75/163 (46.01%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPL--------------------RDIKIHKSDVCYEKIRY-NKSCGFR---PPKERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVD 532
DT+SE E+PPGW +S +G + Y NH+ +Q P + +I+ D ++ Y + F P + + R QK+D +T+ +++ +LS K +V G +GIG E L ++IL C NL K + E K K+++
Sbjct: 11 DTDSEDEMPPGWEERSTKDGWVYYANHLDEKTQWEHPKTGKRKRIAGDLPYGWEQETDENGQIYFVDHLNQRTTYLDPRLAFTVEDQPTKMNTR--QKYDGNTTAMEILQGCDLSGKVVIVTGANTGIGFETARSLALHGTLVILACRNLQKGN-EAKHKILE 170 HSP 2 Score: 54.299 bits (129), Expect = 4.206e-18 Identity = 51/159 (32.08%), Postives = 80/159 (50.31%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR--AIKE----LNLCELNPSSQEYNGFYSYALSSLCKILIVKY--SKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTL 1004
+ +++ +A + P+ ++EDG E +FQVN L FY+ +L L + RVV +S ESHR IK+ L+L L+P ++Y +Y S LC IL K +L + + HPGN++Y +SI R +F PFTK++
Sbjct: 204 LHVLICNAAYLGGPWQLTEDGLEMTFQVNHLGHFYLVSLLQDVL---QRSIPSRVVVVSSESHRFTEIKDSSGKLDLNLLSPLKKDYWAMLAYNRSKLCNILFSKELNRRLSPHGVTSN------AVHPGNMMY-SSIHRNWWGYTLLFALVRPFTKSM 352
BLAST of WW domain-containing oxidoreductase vs. Ensembl Xenopus
Match: runx1 (RUNX family transcription factor 1 [Source:Xenbase;Acc:XB-GENE-483164]) HSP 1 Score: 58.5362 bits (140), Expect = 4.719e-18 Identity = 45/163 (27.61%), Postives = 75/163 (46.01%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPL--------------------RDIKIHKSDVCYEKIRY-NKSCGFR---PPKERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVD 532
DT+SE E+PPGW +S +G + Y NH+ +Q P + +I+ D ++ Y + F P + + R QK+D +T+ +++ +LS K +V G +GIG E L ++IL C NL K + E K K+++
Sbjct: 11 DTDSEDEMPPGWEERSTKDGWVYYANHLDEKTQWEHPKTGKRKRIAGDLPYGWEQETDENGQIYFVDHLNQRTTYLDPRLAFTVEDQPTKMNTR--QKYDGNTTAMEILQGCDLSGKVVIVTGANTGIGFETARSLALHGTLVILACRNLQKGN-EAKHKILE 170 HSP 2 Score: 54.6842 bits (130), Expect = 4.719e-18 Identity = 51/159 (32.08%), Postives = 80/159 (50.31%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR--AIKE----LNLCELNPSSQEYNGFYSYALSSLCKILIVKY--SKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTL 1004
+ +++ +A + P+ ++EDG E +FQVN L FY+ +L L + RVV +S ESHR IK+ L+L L+P ++Y +Y S LC IL K +L + + HPGN++Y +SI R +F PFTK++
Sbjct: 204 LHVLICNAAYLGGPWQLTEDGLEMTFQVNHLGHFYLVSLLQDVL---QRSIPSRVVVVSSESHRFTEIKDSSGKLDLNLLSPLKKDYWAMLAYNRSKLCNILFSKELNRRLSPHGVTSN------AVHPGNMMY-SSIHRNWWGYTLLFALVRPFTKSM 352
BLAST of WW domain-containing oxidoreductase vs. Ensembl Xenopus
Match: wdr91 (WD repeat domain 91 [Source:NCBI gene;Acc:780034]) HSP 1 Score: 77.0258 bits (188), Expect = 1.098e-13 Identity = 42/141 (29.79%), Postives = 74/141 (52.48%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKKKS-RYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
+K+ L+ + + NTL F + K D+ K V+ L +Q+ DL+ L++ W E F L+ + T +K+ +F+ +LV ++ +T+K + FFQ T L ++ EW +WF P + P ++ F YF+R W
Sbjct: 12 VKEYLTFRGFTNTLKYFEVDIKADKDKGFCVDRIVEQLLQFVQSYDLNGLVEYWAYLERRLFSRLEDVYRPTIHKLKTSLFRYYLVYTIQSSRTDKAHEFFQKQAT-ELQNQAEWKEWFALPFLPTPDSNRTFSTYFSRQW 151 HSP 2 Score: 73.559 bits (179), Expect = 1.364e-12 Identity = 79/337 (23.44%), Postives = 149/337 (44.21%), Query Frame = 1
Query: 2503 FHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXXXA-----------LPHGVISLYDAESWSAIQTNLITLKSDFTVNCMYC--SSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKIN--GTTLLDSVYLNAGHNSPVICID 3468
+ EH S + H + S ASLDV G KIW+++ +S K + S +W ++ ++LLG++ G+V++YD + + E+ I PRI + S + FVC + + + ++ +P G + L+D ++ Q VNC + N + G ++G I+L D++ ++ S G EV +V ++D N + + + +D+ + + E S +D P + Y G + + FPR L A+ + + + + G ++ K+N G+TL + + L GH +PV+ +D
Sbjct: 276 YAEHHSSIMHCRVD-CSGRRVASLDVDGVIKIWSLDGIMQTKASAIS-KSALLSLEWATKRDRLLLLGSEVGTVRLYDTEAKKNLCEIGIVEDMPRILSLACSPSGASFVCSAAAATSPSQTDPTYYSYGESGNNQVP-GKLLLWDTKTMKQ-QLQFSLEPVPIAVNCTAFNHNGNLLVTGAADGFIRLFDMQ--QHQCALSWKAHMG-EVYSVD---------FSYDENAVYSIGEDGKFIQWDIHKSGQKV-SEYSLPSDATGPFMLS--GYSGYKQVQFPRGRLF--AFDSEGKYMLTCSSTGGVIYKLNSDGSTLENCLSL-GGHRAPVVTVD 590
BLAST of WW domain-containing oxidoreductase vs. Ensembl Xenopus
Match: wdr91 (WD repeat domain 91 [Source:NCBI gene;Acc:780034]) HSP 1 Score: 77.0258 bits (188), Expect = 1.193e-13 Identity = 42/141 (29.79%), Postives = 74/141 (52.48%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKKKS-RYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
+K+ L+ + + NTL F + K D+ K V+ L +Q+ DL+ L++ W E F L+ + T +K+ +F+ +LV ++ +T+K + FFQ T L ++ EW +WF P + P ++ F YF+R W
Sbjct: 12 VKEYLTFRGFTNTLKYFEVDIKADKDKGFCVDRIVEQLLQFVQSYDLNGLVEYWAYLERRLFSRLEDVYRPTIHKLKTSLFRYYLVYTIQSSRTDKAHEFFQKQAT-ELQNQAEWKEWFALPFLPTPDSNRTFSTYFSRQW 151 HSP 2 Score: 74.7146 bits (182), Expect = 5.597e-13 Identity = 80/338 (23.67%), Postives = 153/338 (45.27%), Query Frame = 1
Query: 2503 FHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXXXA-----------LPHGVISLYDAESW-SAIQTNLITLKSDFTVNCMYC--SSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKIN--GTTLLDSVYLNAGHNSPVICID 3468
+ EH S + H + S ASLDV G KIW+++ +S K + S +W ++ ++LLG++ G+V++YD + + E+ I PRI + S + FVC + + + ++ +P G + L+D ++ +Q +L + VNC + N + G ++G I+L D++ ++ S G EV +V ++D N + + + +D+ + + E S +D P + Y G + + FPR L A+ + + + + G ++ K+N G+TL + + L GH +PV+ +D
Sbjct: 300 YAEHHSSIMHCRVD-CSGRRVASLDVDGVIKIWSLDGIMQTKASAIS-KSALLSLEWATKRDRLLLLGSEVGTVRLYDTEAKKNLCEIGIVEDMPRILSLACSPSGASFVCSAAAATSPSQTDPTYYSYGESGNNQVP-GKLLLWDTKTMKQQLQFSLEPVP--IAVNCTAFNHNGNLLVTGAADGFIRLFDMQ--QHQCALSWKAHMG-EVYSVD---------FSYDENAVYSIGEDGKFIQWDIHKSGQKV-SEYSLPSDATGPFMLS--GYSGYKQVQFPRGRLF--AFDSEGKYMLTCSSTGGVIYKLNSDGSTLENCLSL-GGHRAPVVTVD 614
BLAST of WW domain-containing oxidoreductase vs. Ensembl Mouse
Match: Wwox (WW domain-containing oxidoreductase [Source:MGI Symbol;Acc:MGI:1931237]) HSP 1 Score: 111.309 bits (277), Expect = 3.267e-33 Identity = 70/219 (31.96%), Postives = 114/219 (52.05%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSL--FSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYLTTKINQIKI 1178
+ ++V +AG + P+ +++DG ET+FQVN L FY+ ++L L SP RV+ +S ESHR + +L+L L+P +Y +Y S LC IL + +L + + HPGN++Y ++I R + K +F PFTK++ Q AAT + C ++ + G YFNN C C P+ QS+ LW L+ ++ Q ++
Sbjct: 204 LHVLVCNAGTFALPWGLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSSP-----ARVIVVSSESHRFTDINDSSGKLDLSRLSPPRSDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-SAIHRNSWVYKLLFTLARPFTKSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQSEETARALWE-LSERLIQDRL 409 HSP 2 Score: 52.373 bits (124), Expect = 3.267e-33 Identity = 39/164 (23.78%), Postives = 66/164 (40.24%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIKIH-KSDVCY---EKIRYNKSCGFRPPKERHKRFI------------------QKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTK 541
DT+SE ELPPGW ++ +G + Y NH +Q P + D+ Y ++ N F + ++ Q++D +T+ +++ + + K LV G SGIG E +IL C NL + + L ++ K
Sbjct: 11 DTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHK 174
BLAST of WW domain-containing oxidoreductase vs. Ensembl Mouse
Match: Wwox (WW domain-containing oxidoreductase [Source:MGI Symbol;Acc:MGI:1931237]) HSP 1 Score: 73.9442 bits (180), Expect = 3.745e-22 Identity = 51/161 (31.68%), Postives = 84/161 (52.17%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSL--FSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTL 1004
+ ++V +AG + P+ +++DG ET+FQVN L FY+ ++L L SP RV+ +S ESHR + +L+L L+P +Y +Y S LC IL + +L + + HPGN++Y ++I R + K +F PFTK++
Sbjct: 204 LHVLVCNAGTFALPWGLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSSP-----ARVIVVSSESHRFTDINDSSGKLDLSRLSPPRSDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-SAIHRNSWVYKLLFTLARPFTKSM 352 HSP 2 Score: 52.373 bits (124), Expect = 3.745e-22 Identity = 39/164 (23.78%), Postives = 66/164 (40.24%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIKIH-KSDVCY---EKIRYNKSCGFRPPKERHKRFI------------------QKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTK 541
DT+SE ELPPGW ++ +G + Y NH +Q P + D+ Y ++ N F + ++ Q++D +T+ +++ + + K LV G SGIG E +IL C NL + + L ++ K
Sbjct: 11 DTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHK 174
BLAST of WW domain-containing oxidoreductase vs. Ensembl Mouse
Match: Wwox (WW domain-containing oxidoreductase [Source:MGI Symbol;Acc:MGI:1931237]) HSP 1 Score: 73.9442 bits (180), Expect = 4.381e-22 Identity = 51/161 (31.68%), Postives = 84/161 (52.17%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSL--FSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTL 1004
+ ++V +AG + P+ +++DG ET+FQVN L FY+ ++L L SP RV+ +S ESHR + +L+L L+P +Y +Y S LC IL + +L + + HPGN++Y ++I R + K +F PFTK++
Sbjct: 204 LHVLVCNAGTFALPWGLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSSP-----ARVIVVSSESHRFTDINDSSGKLDLSRLSPPRSDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-SAIHRNSWVYKLLFTLARPFTKSM 352 HSP 2 Score: 52.373 bits (124), Expect = 4.381e-22 Identity = 39/164 (23.78%), Postives = 66/164 (40.24%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIKIH-KSDVCY---EKIRYNKSCGFRPPKERHKRFI------------------QKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTK 541
DT+SE ELPPGW ++ +G + Y NH +Q P + D+ Y ++ N F + ++ Q++D +T+ +++ + + K LV G SGIG E +IL C NL + + L ++ K
Sbjct: 11 DTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHK 174
BLAST of WW domain-containing oxidoreductase vs. Ensembl Mouse
Match: Rdh11 (retinol dehydrogenase 11 [Source:MGI Symbol;Acc:MGI:102581]) HSP 1 Score: 70.0922 bits (170), Expect = 8.152e-14 Identity = 55/206 (26.70%), Postives = 95/206 (46.12%), Query Frame = 3
Query: 546 REIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYAL----SSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWN 1145
+ + L++ +AG+M P+S + DGFE VN L F + L R+V LS H +L ++ + + FYS L S L IL K +LK + + HPG V ++ +TRY I+++++ F F KT + A T + C ++ +S SG +F++ + + G+++I LW+
Sbjct: 116 KHLHLLINNAGVMMCPYSKTADGFEMHIGVNHLGHFL---LTHLLLEKLKESAPSRIVNLSSLGH------HLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTKELAKRLKGSGVTT------YSVHPGTV--HSELTRYSSIMRWLWQLFFVFIKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIARRLWD 304 HSP 2 Score: 28.1054 bits (61), Expect = 8.152e-14 Identity = 16/58 (27.59%), Postives = 27/58 (46.55%), Query Frame = 2
Query: 380 NLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTKISGN 553
L K A+V G +GIG E L + + L C ++ K +L + + ++GN
Sbjct: 35 QLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAR----EIQAVTGN 88
BLAST of WW domain-containing oxidoreductase vs. Ensembl Mouse
Match: Rdh11 (retinol dehydrogenase 11 [Source:MGI Symbol;Acc:MGI:102581]) HSP 1 Score: 70.0922 bits (170), Expect = 1.052e-13 Identity = 55/206 (26.70%), Postives = 95/206 (46.12%), Query Frame = 3
Query: 546 REIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYAL----SSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWN 1145
+ + L++ +AG+M P+S + DGFE VN L F + L R+V LS H +L ++ + + FYS L S L IL K +LK + + HPG V ++ +TRY I+++++ F F KT + A T + C ++ +S SG +F++ + + G+++I LW+
Sbjct: 100 KHLHLLINNAGVMMCPYSKTADGFEMHIGVNHLGHFL---LTHLLLEKLKESAPSRIVNLSSLGH------HLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTKELAKRLKGSGVTT------YSVHPGTV--HSELTRYSSIMRWLWQLFFVFIKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIARRLWD 288 HSP 2 Score: 27.7202 bits (60), Expect = 1.052e-13 Identity = 16/58 (27.59%), Postives = 27/58 (46.55%), Query Frame = 2
Query: 380 NLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTKISGN 553
L K A+V G +GIG E L + + L C ++ K +L + + ++GN
Sbjct: 19 QLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAR----EIQAVTGN 72
BLAST of WW domain-containing oxidoreductase vs. UniProt/SwissProt
Match: sp|Q91WL8|WWOX_MOUSE (WW domain-containing oxidoreductase OS=Mus musculus OX=10090 GN=Wwox PE=1 SV=1) HSP 1 Score: 111.309 bits (277), Expect = 2.005e-32 Identity = 70/219 (31.96%), Postives = 114/219 (52.05%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSL--FSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYLTTKINQIKI 1178
+ ++V +AG + P+ +++DG ET+FQVN L FY+ ++L L SP RV+ +S ESHR + +L+L L+P +Y +Y S LC IL + +L + + HPGN++Y ++I R + K +F PFTK++ Q AAT + C ++ + G YFNN C C P+ QS+ LW L+ ++ Q ++
Sbjct: 204 LHVLVCNAGTFALPWGLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSSP-----ARVIVVSSESHRFTDINDSSGKLDLSRLSPPRSDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-SAIHRNSWVYKLLFTLARPFTKSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQSEETARALWE-LSERLIQDRL 409 HSP 2 Score: 52.373 bits (124), Expect = 2.005e-32 Identity = 39/164 (23.78%), Postives = 66/164 (40.24%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIKIH-KSDVCY---EKIRYNKSCGFRPPKERHKRFI------------------QKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTK 541
DT+SE ELPPGW ++ +G + Y NH +Q P + D+ Y ++ N F + ++ Q++D +T+ +++ + + K LV G SGIG E +IL C NL + + L ++ K
Sbjct: 11 DTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVLVTGANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHK 174
BLAST of WW domain-containing oxidoreductase vs. UniProt/SwissProt
Match: sp|Q9NZC7|WWOX_HUMAN (WW domain-containing oxidoreductase OS=Homo sapiens OX=9606 GN=WWOX PE=1 SV=1) HSP 1 Score: 105.916 bits (263), Expect = 1.755e-30 Identity = 67/220 (30.45%), Postives = 112/220 (50.91%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYLTTKINQIKIVNQ 1187
+ ++V +A + P+S+++DG ET+FQVN L FY+ ++L L RV+ +S ESHR ++ +L+ L+P+ +Y +Y S LC IL + +L + + HPGN++Y ++I R + +F PFTK++ Q AAT + C + G YFNN C C P+ QS+ LW L+ ++ Q ++ +Q
Sbjct: 204 LHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLC---RSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-SNIHRSWWVYTLLFTLARPFTKSMQQGAATTVYCAAVPELEGLGGMYFNNCCRCMPSPEAQSEETARTLW-ALSERLIQERLGSQ 412 HSP 2 Score: 50.8322 bits (120), Expect = 1.755e-30 Identity = 37/164 (22.56%), Postives = 66/164 (40.24%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIKIH-KSDVCY---EKIRYNKSCGFRPPKERHKRFI------------------QKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTK 541
DT+SE ELPPGW ++ +G + Y NH +Q P + D+ Y ++ N F + ++ Q++D +T+ +++ + + K +V G SGIG E +IL C N+ + + L ++ K
Sbjct: 11 DTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHK 174
BLAST of WW domain-containing oxidoreductase vs. UniProt/SwissProt
Match: sp|Q5R9W5|WWOX_PONAB (WW domain-containing oxidoreductase OS=Pongo abelii OX=9601 GN=WWOX PE=2 SV=1) HSP 1 Score: 106.686 bits (265), Expect = 1.970e-30 Identity = 66/220 (30.00%), Postives = 113/220 (51.36%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYLTTKINQIKIVNQ 1187
+ ++V +A + P+S+++DG ET+FQVN L FY+ ++L L RV+ +S ESHR ++ +L+ L+P+ +Y +Y S LC +L + +L + + HPGN++Y ++I R + +F PFTK++ Q AAT + C + + G YFNN C C P+ QS+ LW L+ ++ Q ++ +Q
Sbjct: 204 LHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLC---RSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNVLFSNELHRRLSPRGVTSN------AVHPGNMMY-SNIHRSWWVYTLLFTLARPFTKSMQQGAATTVYCAAAPELEGLGGMYFNNCCRCMPSPEAQSEETARTLW-ALSERLIQERLGSQ 412 HSP 2 Score: 50.0618 bits (118), Expect = 1.970e-30 Identity = 39/168 (23.21%), Postives = 64/168 (38.10%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIKIHKSDVCYEKIRY------------------NKSCGFRPPK--------ERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTK 541
DT+SE ELPPGW ++ +G + Y NH +Q P K K + Y NK + P+ Q++D +T+ +++ + + K +V G SGIG E +IL C N+ + + L ++ K
Sbjct: 11 DTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHP----KTGKRKRVAGDLPYGWEQGTDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTALEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHK 174
BLAST of WW domain-containing oxidoreductase vs. UniProt/SwissProt
Match: sp|Q05B30|WDR91_XENTR (WD repeat-containing protein 91 OS=Xenopus tropicalis OX=8364 GN=wdr91 PE=2 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 7.815e-29 Identity = 174/754 (23.08%), Postives = 332/754 (44.03%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKK-KSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWXXXXXXXXXXXXXQV-----VRSVMSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNAGKSQIISQV---ISNLHGSGRTLHDVSDLLCDFRLTRENKQIEYRRASKSNKPKGI--SLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSN-QSSPNLADLDNS-VSMIE-----NSINSTVIGNIAPQASSEIN-KNSSAD---------------SFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXXXA-----------LPHGVISLYDAESW-SAIQTNLITLKSDFTVNCMYC--SSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKIN--GTTLLDSVYLNAGHNSPVICID 3468
+K+ L+ + + NTL F + K D+ K + V+ L +Q+ DL+ L++ W E F L+ + T +K+ +F+ +LV ++ +T+K + FFQ T L ++ EW +WF P + P ++ F YF+R W D F +S+ NF + V ++++ SD + L + EN I + K + + Y L + ++ ++ +SN+ G S+L + + N + + S + G SL+ QNK K P + L + P + +V K + +A+ + +SSPN+ + + SM++ ++ A Q S+E +NS AD + G ++ +K +P + ++ + EH S + H + S ASLDV G KIW+++ +S K + S +W ++ ++LLG++ G+V++YD + + E+ I PRI + S + FVC + + + ++ +P G + L+D ++ +Q +L + VNC + N + G ++G I+L D++ ++ S G EV +V ++D N + + + +D+ + + E S +D P + Y G + + FPR L A+ + + + + G ++ K+N G+TL + + L GH +PV+ +D
Sbjct: 12 VKEYLTFRGFTNTLKYFEVDIKADKDKGFRVDRIVEQLLQFVQSYDLNGLVEYWAYLERRLFSRLEDVYRPTIHKLKTSLFRYYLVYTIQSSRTDKAHEFFQKQAT-ELQNQAEWKEWFALPFLPTPDSNRTFSTYFSRQWADTFTVSLHNFLSVLFQCMPVPKILTFQSDYQKIACL--QEENEI--MRQKLFALQAETYRLRKDGPSEPLVLHKLPHYVSNMDRLGD-----SELGSNIMSSHSNTNMN----TPSQRTSGFLSSLLAQNK-KPPPPKSTLPSVSSPTQSGGSVPLKKEVAVSQAQKAKELVGGTKEVRSSPNILGVPGTESSMVQQRHKRQQERKELLSKTASQVSTEKKAENSDADPDLRSDTQNDTVDAVTRGSGASGARKEEKPAQPFIVLSQDE-----YAEHHSSIMHCRVD-CSGRRVASLDVDGVIKIWSLDGIMQTKASAIS-KSALLSLEWATKRDRLLLLGSEVGTVRLYDTEAKKNLCEIGIVEDMPRILSLACSPSGASFVCSAAAATSPSQTDPTYYSYGESGNNQVP-GKLLLWDTKTMKQQLQFSLEPVP--IAVNCTAFNHNGNLLVTGAADGFIRLFDMQ--QHQCALSWKAHMG-EVYSVD---------FSYDENAVYSIGEDGKFIQWDIHKSGQKV-SEYSLPSDATGPFMLSG--YSGYKQVQFPRGRLF--AFDSEGKYMLTCSSTGGVIYKLNSDGSTLENCLSL-GGHRAPVVTVD 722
BLAST of WW domain-containing oxidoreductase vs. UniProt/SwissProt
Match: sp|Q9VLU5|WWOX_DROME (WW domain-containing oxidoreductase OS=Drosophila melanogaster OX=7227 GN=Wwox PE=2 SV=1) HSP 1 Score: 120.939 bits (302), Expect = 9.352e-28 Identity = 71/206 (34.47%), Postives = 110/206 (53.40%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR----AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLW 1142
Q ID ++ +AG+ + P++ + DG ET+FQV+ LS FY+ + L +LF K R++ LS ESHR ++ L + L+P ++Y +Y + LC +L + +W R F HPGN+V ++ ++R + +F PFTK+L QAAAT I C +N SG YFNN C+P+ L +S + LW
Sbjct: 198 QSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLT-LQLETLFD----YKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWK----QRGISVFSLHPGNMV-SSDLSRNYWFYRLLFAIVRPFTKSLQQAAATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLW 393
BLAST of WW domain-containing oxidoreductase vs. TrEMBL
Match: A0A154PPU7 (WW domain-containing oxidoreductase OS=Dufourea novaeangliae OX=178035 GN=WN55_06275 PE=4 SV=1) HSP 1 Score: 138.272 bits (347), Expect = 8.024e-39 Identity = 79/221 (35.75%), Postives = 123/221 (55.66%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR-----AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYLTTKINQIKIVN 1184
QK+ + +++ +AG+ + P+ ++EDG+ET+FQVN LS FY +L + S HN RVV +S ESHR +++ + L+P + +Y +Y S LC IL + +W S+ F CHPGN+V ++S++RY IL+F+F PFTK+L QAA+T + C + + +G YFNN CDP+ LW+ ++Q IVN
Sbjct: 195 QKYGTLHILILNAGVFAIPYELTEDGYETTFQVNHLSHFYFTLLLEHPIRSCHN---ARVVVVSSESHRFSTLQTVEDFHQLNLSPPAYKYWFMGAYNDSKLCNILFTQELAKRWPSVSV------FSCHPGNMV-SSSLSRYSWILRFLFMLVRPFTKSLQQAASTSVFCATAPELEGVTGVYFNNCYCCDPSTTALDSALARRLWS-----VSQEMIVN 400 HSP 2 Score: 54.6842 bits (130), Expect = 8.024e-39 Identity = 43/150 (28.67%), Postives = 67/150 (44.67%), Query Frame = 2
Query: 119 DTESEYELPPGWTKSIN-NGTIIYNNHIINISQLYSPLRD-IKIHKSDV--CYEK-----------IRYNKSCGFRPPK--------ERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIK 499
D++SE ELPPGW + +G + Y NH +Q P KI + ++ +E+ N++ + P+ E + Q+FD ST+ V+ +L K A+V G +GIG E L C +IL C +L K
Sbjct: 7 DSDSEDELPPGWEEMTTIDGNVYYVNHYTKGTQWTHPRTGRQKIVEGELPSGWERRVTDDGKVLFVDHMNRTTTYSDPRLAFATEYRELSQPVRQRFDGSSTALAVLYGRDLRGKVAIVTGANTGIGFETARSLALHGCKVILTCRDLKK 156
BLAST of WW domain-containing oxidoreductase vs. TrEMBL
Match: A0A151X589 (WW domain-containing oxidoreductase OS=Trachymyrmex zeteki OX=64791 GN=ALC60_05629 PE=4 SV=1) HSP 1 Score: 133.265 bits (334), Expect = 1.897e-38 Identity = 74/207 (35.75%), Postives = 118/207 (57.00%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR-----AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLW 1142
QKF+ +D+++ +AG+ P+ +++DG+ET+FQVN LS FY+ +L ++ S +N R+V +S ESHR I++L+ L+ + +Y +Y S LC IL V+ +W S+ F CHPGN+V+ TS++R+ + + +F PFTK+L QAA+T I C + + +G YFNN C C P+ LW
Sbjct: 194 QKFKFLDILILNAGVFGLPYQLTKDGYETTFQVNHLSQFYLTLLLKQTIQSSNNP---RIVVVSSESHRFSSIQTIEDLHQLTLSLPAYKYWAMAAYNESKLCNILFVQELARQWPSVGV------FACHPGNLVF-TSLSRHWWLYRLLFALARPFTKSLQQAASTIIFCATAPELEGVTGSYFNNCCHCQPSNAALDSALAAQLW 390 HSP 2 Score: 58.151 bits (139), Expect = 1.897e-38 Identity = 46/156 (29.49%), Postives = 73/156 (46.79%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIK-IHKSDV--CYE-------KIRY----NKSCGFRPPK--------ERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELK 517
D++SE ELPPGW ++ +G + Y NH +Q P K I D+ +E K+ Y N++ + P+ E + Q+FD ST+ V++ +L K ALV G +GIG E L C +IL C ++ K + ++
Sbjct: 6 DSDSEDELPPGWEERTTLDGNVYYVNHYTKGTQWTHPRTGRKKIVNGDLPPGWERCISDDGKVLYIDHTNRTTTYTDPRLAFATEYREMSQIIRQRFDGSSTALAVLHGRDLRNKVALVTGANTGIGYETARSLALHGCNVILACRDMEKANEAIR 161
BLAST of WW domain-containing oxidoreductase vs. TrEMBL
Match: A0A0N0BGS5 (WW domain-containing oxidoreductase OS=Melipona quadrifasciata OX=166423 GN=WN51_13253 PE=4 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 2.966e-38 Identity = 72/195 (36.92%), Postives = 115/195 (58.97%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR-----AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTL 1106
QK+R +++++ +AGI + P+ +++DG+ET+FQVN LS FY +L + S K RVV +S ESHR I++ + L+P + +Y +Y S LC IL + +W S++ F CHPGN+V ++S++RY L+F+F PFTK+L QAA+T + C + + + CYFNN C P++
Sbjct: 194 QKYRVLNILILNAGIFAIPYQLTKDGYETTFQVNYLSQFYFTLLLEHPIRSCR---KSRVVIVSSESHRFSSLQTIEDFHQLILSPPAYKYWYMEAYNNSKLCNILFAQELANRWPSVNV------FSCHPGNMV-SSSLSRYSWTLRFLFMLVRPFTKSLQQAASTSVFCATAPELEGVTKCYFNNCYYCIPSI 378 HSP 2 Score: 62.7734 bits (151), Expect = 2.966e-38 Identity = 44/154 (28.57%), Postives = 67/154 (43.51%), Query Frame = 2
Query: 119 DTESEYELPPGWTK-SINNGTIIYNNHIINISQLYSPL--------------------RDIKI----HKSDVCYEKIRYNKSCGFRPPKERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCD 505
D++SE ELPPGW + + N G + Y NH +Q P D ++ HK+ Y R + +R E + Q+FD ST+ V++ +L K A+V G +GIG E L C ++L C +L K +
Sbjct: 7 DSDSEDELPPGWEEMTTNTGNVYYVNHYTKGTQWTHPRTGRTKIVEGELPSGWKKCVSEDGQVLFVHHKNTTTYTDPRLAFATEYR---ESSQPVRQRFDGSSTALSVLHGRDLRNKIAIVTGANTGIGFETARSLALHGCKVVLACRDLKKAE 157
BLAST of WW domain-containing oxidoreductase vs. TrEMBL
Match: A0A195DRL7 (WW domain-containing oxidoreductase OS=Trachymyrmex cornetzi OX=471704 GN=ALC57_12686 PE=4 SV=1) HSP 1 Score: 131.339 bits (329), Expect = 5.558e-38 Identity = 73/207 (35.27%), Postives = 119/207 (57.49%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR-----AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLW 1142
QKF+ +D+++ +AG+ P+ +++DG+ET+FQVN LS FY+ +L ++ S +N R+V +S ESHR ++++L+ L+ + +Y +Y S LC IL V+ +W S+ F CHPGN+V +TS++R+ + + +F PFTK+L QAA+T I C + + +G YFNN C C P+ LW
Sbjct: 194 QKFKFLDILILNAGVFGLPYQLTKDGYETTFQVNHLSQFYLTLLLKQTIQSSNNP---RIVVVSSESHRFSSIRSVEDLHQLTLSVPAYKYWAMAAYNESKLCNILFVQELARQWPSVGV------FGCHPGNLV-STSLSRHWWLYRLLFALARPFTKSLQQAASTIIFCATAPELEGVTGSYFNNCCHCQPSNAALDSALAAQLW 390 HSP 2 Score: 58.5362 bits (140), Expect = 5.558e-38 Identity = 46/156 (29.49%), Postives = 73/156 (46.79%), Query Frame = 2
Query: 119 DTESEYELPPGWT-KSINNGTIIYNNHIINISQLYSPLRDIK-IHKSDV--CYE-------KIRY----NKSCGFRPPK--------ERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELK 517
D++SE ELPPGW ++ +G + Y NH +Q P K I D+ +E K+ Y N++ + P+ E + Q+FD ST+ V++ +L K ALV G +GIG E L C +IL C ++ K + ++
Sbjct: 6 DSDSEDELPPGWEERTTLDGNVYYVNHYTKGTQWMHPRTGRKKIVNGDLPSGWERCISDDGKVLYIDHTNRTTTYTDPRLAFATEYREMSQIIRQRFDGSSTALAVLHGRDLRNKVALVTGANTGIGYETARSLALHGCNVILACRDMEKANEAIR 161
BLAST of WW domain-containing oxidoreductase vs. TrEMBL
Match: A0A088A8B9 (Uncharacterized protein OS=Apis mellifera OX=7460 GN=Wwox PE=4 SV=1) HSP 1 Score: 135.576 bits (340), Expect = 8.127e-38 Identity = 78/221 (35.29%), Postives = 123/221 (55.66%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR-----AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYLTTKINQIKIVN 1184
QK+R + +++ +AG+ + P+ +++DG+ET+FQVN LS FY +L + S HN RVV +S ESHR +++ + L+P + +Y +Y S LC IL + W S++ F CHPGN+V ++S++RY L+ +F PFTK+L QAA+T I C + + +GCYFNN CDP+ LW+ ++Q I+N
Sbjct: 195 QKYRTLHILILNAGVFAIPYQLTKDGYETTFQVNHLSQFYFTLLLEHPIRSCHNS---RVVIVSSESHRFSSLRTVEDFHQLSLSPPAYKYWFMGAYNNSKLCNILFAQELAKYWPSVNV------FSCHPGNMV-SSSLSRYSWTLRLLFMLVRPFTKSLQQAASTSIFCATAPELEGVTGCYFNNCYRCDPSNAALDSALATRLWS-----VSQEMIIN 400 HSP 2 Score: 53.9138 bits (128), Expect = 8.127e-38 Identity = 39/150 (26.00%), Postives = 63/150 (42.00%), Query Frame = 2
Query: 119 DTESEYELPPGWTK-SINNGTIIYNNHIINISQLYSPL--------------RDIKIHKSDVCYEKIRYNKSCGFRPPK--------ERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIK 499
+++SE ELPPGW + + NG + Y NH +Q P + ++ + N + + P+ E Q+FD ST+ V++ +L K A+V G +GIG E L C +I+ C +L K
Sbjct: 7 ESDSEDELPPGWEEMTTANGNVYYVNHYTKGTQWTHPRTGRTKTVEGELPSGWERRVAEDGQVLFVDHINHTTTYTDPRLAFATEYRELSHPMRQRFDGSSTALSVLHGRDLRGKIAIVTGANTGIGFETARSLALHGCTVIIACRDLKK 156
BLAST of WW domain-containing oxidoreductase vs. Ensembl Cavefish
Match: wdr91 (WD repeat domain 91 [Source:NCBI gene;Acc:103023610]) HSP 1 Score: 129.413 bits (324), Expect = 2.959e-30 Identity = 172/762 (22.57%), Postives = 301/762 (39.50%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKK-KSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWXXXXXXXXXXXXXQVVRSVMSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNA--GKSQIISQVISNLHGSGRT--------------------LHDVSDLLCDFRLTRENKQIEYRRASKSNKPKGISLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSNQSSPNLADLDNSVSMIENSINSTVIGNIAPQASSEINKNSSADSFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXX------XXXXXXXXXALP-HGVISLYDAESWSAIQTNLITLKSDFTVNCMYC--SSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSH--LNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKIN-GTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTI 3537
+++ L + + + L E K D+ K + +D LQ+ IQT DL L + W + F L+ + T + +++ +F+ +LV +N+ EK FFQ L + EW DWF P + P ++ F YF+ W D ++ L N+ S+ L CI+ I +P ++ + S + +S+ + Q++ L G + L D DL+ R T N R + P+G +T P + + A + ++ A + +G K K D + P D+ +++ S G++Q K+SQ+ + EH S + H + S ASLDV G K+W+ N P ++ T+ K + S +W ++ ++LLG+ G+V++YD + + EM ID A PRI + S + FVC + ++LP G + L+D ++ Q VNC + N + G ++G I+L D++ E + S +G EV +V ++D N + + + F N +S K+S + D V P + Y G + + PR L A+ + + + + G L+ ++N G L+SV GH +PV+ +D D L+ +M+G I
Sbjct: 12 VREYLIYRGFTSALKHLDSEIKSDKEKGFRVDKIIDQLQHFIQTYDLAGLKEYWGYLDRRLFSRLEDVYRPTVNKLRTSLFRYYLVHTIQNQ--EKTQEFFQKQAA-ELQGQAEWRDWFVLPFIPVPEQNPAFSPYFSLQWAD------------------TFLVSLHNFLSV---LFQCISLIFPPQPVLLSFDAEVQRSTSIQEESEQLRQMLFALQGESKAKKAEEMVHHKLPAYVQHMDRLGDTEDLVTSQRAT--NPITPSRNFFSTFLPQGRR--TPARTPQGPPGSSPTQAA---LGRKDPTAGQVRVRGSEK----KADSSDTEGQPETDTTDS--------------------PTNQTRSGSEVGGPGVEQPFIKLSQEEYG----------------EHHSSIMHCRVD-CSGRRVASLDVDGVVKVWSFN-PIMQTKATIMSKSPLLSLEWATKPDRLLLLGSGVGTVRLYDTEAKKNLYEMTIDDAHPRILSLAYSPSGTSFVCSAAANVSRPGSVTEMMPRASLPVSGQLLLWDTKTVKQ-QLQFALEPGPVAVNCTAFNHNGNLLVTGAADGWIRLFDMQRYE--SVMSWKAHDG-EVYSV---------EFSYDENTVFSIGEDGK---FIQWNIHRSGVKQSEYSLSQDAVGPFVLSG--YSGYKQVQVPRGRLF--AFDSEGQHVLTCSSTGGLIYRLNKGEAGLESVLSLGGHKAPVVTVDW----CSAVDCGTCLTASMDGKI 676
BLAST of WW domain-containing oxidoreductase vs. Ensembl Cavefish
Match: wdr91 (WD repeat domain 91 [Source:NCBI gene;Acc:103023610]) HSP 1 Score: 90.1225 bits (222), Expect = 6.690e-18 Identity = 92/357 (25.77%), Postives = 157/357 (43.98%), Query Frame = 1
Query: 2503 FHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXX------XXXXXXXXXALP-HGVISLYDAESWSAIQTNLITLKSDFTVNCMY--CSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSH--LNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKIN-GTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTI 3537
+ EH S + H + S ASLDV G K+W+ N P ++ T+ K + S +W ++ ++LLG+ G+V++YD + + EM ID A PRI + S + FVC + ++LP G + L+D ++ Q VNC + N + G ++G I+L D++ E + S +G EV +V ++D N + + + F N +S K+S + D V P + Y G + + PR L A+ + + + + G L+ ++N G L+SV GH +PV+ +D D L+ +M+G I
Sbjct: 388 YGEHHSSIMHCRVD-CSGRRVASLDVDGVVKVWSFN-PIMQTKATIMSKSPLLSLEWATKPDRLLLLGSGVGTVRLYDTEAKKNLYEMTIDDAHPRILSLAYSPSGTSFVCSAAANVSRPGSVTEMMPRASLPVSGQLLLWDTKTVKQ-QLQFALEPGPVAVNCTAFNHNGNLLVTGAADGWIRLFDMQRYE--SVMSWKAHDG-EVYSV---------EFSYDENTVFSIGEDGK---FIQWNIHRSGVKQSEYSLSQDAVGPFVLSG--YSGYKQVQVPRGRLF--AFDSEGQHVLTCSSTGGLIYRLNKGEAGLESVLSLGGHKAPVVTVDW----CSAVDCGTCLTASMDGKI 718 HSP 2 Score: 68.9366 bits (167), Expect = 2.834e-11 Identity = 40/141 (28.37%), Postives = 67/141 (47.52%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKK-KSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
+++ L + + + L E K D+ K + +D LQ+ IQT DL L + W + F L+ + T + +++ +F+ +LV + K EK FFQ L + EW DWF P + P ++ F YF+ W
Sbjct: 12 VREYLIYRGFTSALKHLDSEIKSDKEKGFRVDKIIDQLQHFIQTYDLAGLKEYWGYLDRRLFSRLEDVYRPTVNKLRTSLFRYYLVHTIQMKNQEKTQEFFQKQAA-ELQGQAEWRDWFVLPFIPVPEQNPAFSPYFSLQW 151
BLAST of WW domain-containing oxidoreductase vs. Ensembl Cavefish
Match: zgc:153441 (retinol dehydrogenase 12-like [Source:NCBI gene;Acc:103027802]) HSP 1 Score: 83.9593 bits (206), Expect = 8.336e-17 Identity = 57/206 (27.67%), Postives = 98/206 (47.57%), Query Frame = 3
Query: 549 EIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKY--SKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRY----QPILKFIFWFFSP-FTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWN 1145
+D+++ +AG+M P S++EDG+ET F VN L F + + L N R++ +S +H+ K ++ +LN + YN SY S L +L + ++K + F HPG V T + RY P++ + + KT Q A T I C I+ + ++GCYF++ + +P L + + LW+
Sbjct: 132 RLDILINNAGVMMCPHSLTEDGYETQFAVNHLGHFL---LTVLLLDMLKNSTPSRIINVSSIAHKGGK-IHFDDLNFNKTPYNSLISYRQSKLANVLFTRELSRRIKGSGVTA------FAVHPG--VIRTELGRYVEMRHPVVSTLLSLPAILLMKTPKQGAQTTIYCTITEGLEKYNGCYFSDCRMMEPALEAKDDLAAMRLWD 325
BLAST of WW domain-containing oxidoreductase vs. Ensembl Cavefish
Match: zgc:153441 (retinol dehydrogenase 12-like [Source:NCBI gene;Acc:103027802]) HSP 1 Score: 83.9593 bits (206), Expect = 9.279e-17 Identity = 57/206 (27.67%), Postives = 98/206 (47.57%), Query Frame = 3
Query: 549 EIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKY--SKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRY----QPILKFIFWFFSP-FTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWN 1145
+D+++ +AG+M P S++EDG+ET F VN L F + + L N R++ +S +H+ K ++ +LN + YN SY S L +L + ++K + F HPG V T + RY P++ + + KT Q A T I C I+ + ++GCYF++ + +P L + + LW+
Sbjct: 126 RLDILINNAGVMMCPHSLTEDGYETQFAVNHLGHFL---LTVLLLDMLKNSTPSRIINVSSIAHKGGK-IHFDDLNFNKTPYNSLISYRQSKLANVLFTRELSRRIKGSGVTA------FAVHPG--VIRTELGRYVEMRHPVVSTLLSLPAILLMKTPKQGAQTTIYCTITEGLEKYNGCYFSDCRMMEPALEAKDDLAAMRLWD 319
BLAST of WW domain-containing oxidoreductase vs. Ensembl Cavefish
Match: rdh12l (retinol dehydrogenase 12-like [Source:NCBI gene;Acc:103044420]) HSP 1 Score: 73.1738 bits (178), Expect = 2.190e-13 Identity = 53/206 (25.73%), Postives = 100/206 (48.54%), Query Frame = 3
Query: 546 REIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSL--FSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRY-QPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEM---LWN 1145
+++++++ +AG+M P+ + DGFE VN + F + +L+ + SP R+V +S +H+ +N+ ++N S + Y+ +Y+ S L +L + D +V HPG V T + R+ + + W PFTKT Q A T I C ++ ++ SG Y+++ C P + ++ +M LW+
Sbjct: 97 KQVNILINNAGVMVCPYGKTADGFEMQIGVNHMGHFLLTFLLMDLIKKSSP-----ARIVNVSSMAHK-WGTINIDDIN-SEKSYDKSKAYSQSKLANVLFTRCLAKHLDGTGV----TVYVLHPG--VVQTELWRHLNRAQQGVMWMVKPFTKTSVQGAQTTIYCAVAPELETESGKYYSD---CAPASCSNAAMDDDMAKRLWD 286
BLAST of WW domain-containing oxidoreductase vs. Ensembl Sea Lamprey
Match: wdr91 (WD repeat domain 91 [Source:NCBI gene;Acc:402898]) HSP 1 Score: 80.8777 bits (198), Expect = 9.234e-16 Identity = 79/360 (21.94%), Postives = 161/360 (44.72%), Query Frame = 1
Query: 2503 FHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXX------XXXXXALPHGVISLYDAESWSAIQTNLITLKSD-FTVNCMY--CSSNTIFAGCSNGSIKLIDIRVPENYNT-NSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPY-----GGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKINGTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTI 3537
+ EH S + H K S S AS+DV G K+W+ + P+ ++ T+ K + S +W ++ ++LLG+ GSV+ YD + + V ++ +D+A+PR+ + + FVC + + ++ + G +SL+DA++ Q +L TL + + C+ + N + G ++G I+L D+ + Y+ S G+ +C ++S D + + + + + ++ + + H + A P+ G + + PR L + + + L +A GI+ + +G+ L GH +PV+ ++ D + L+ +M+G I
Sbjct: 353 YSEHHSPIMHCKFD-ASGSRVASVDVDGVVKVWSCS-PTPQTHTTVMAKSPLLSLEWATKPHRLLLLGSGIGSVRFYDTDQKKSVADVTLDMAYPRVLALACSPTGGSFVCGAAASAHGNGTSPPEAAGGSATRGQLSLWDAKTLR--QQHLFTLDPEPVAITCVSFNHNGNLLVCGATDGLIRLYDV---QRYDCLMSWRAHHGE-------VCSVEFS---GDETGVFSMGADGKFTQWHLQREGARVAELEVHAD--------AAGPFEVCGCSGYKQTHAPRGRLFAFEPSSGQHVLTCSAHGGIVYRLESGS--LSPCLTLGGHRAPVVTVEW----TTAMDCGMCLTASMDGKI 681 HSP 2 Score: 69.3218 bits (168), Expect = 4.108e-12 Identity = 38/145 (26.21%), Postives = 67/145 (46.21%), Query Frame = 1
Query: 1357 IKQILSIKEYKNTLHSFFEEEKIDRPKKKSRYFVDIL-----QNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLW 1776
++ L + + TL ++ E + DR S VD + Q + + DL SL +W E F L+ T +++ + +A++ + + +K FFQ +G + S +EW +WF P + +P H F YFT+ W
Sbjct: 12 VRDFLVFRGFAATLRAYEAELRGDR---DSGARVDTISLPPSQLCVSSLDLQSLRDLWAHLEKRLFSRLEHAHLLTTCKLRTGVLRAYVAHSVQAGRPDKTLEFFQRVGPELHGS-SEWREWFALPFLPSPETHSTFSAYFTKQW 152
BLAST of WW domain-containing oxidoreductase vs. Ensembl Sea Lamprey
Match: rdh14b (retinol dehydrogenase 14b [Source:ZFIN;Acc:ZDB-GENE-030131-6605]) HSP 1 Score: 56.225 bits (134), Expect = 1.874e-8 Identity = 49/187 (26.20%), Postives = 86/187 (45.99%), Query Frame = 3
Query: 549 EIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRY-------QPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNN 1082
+D++V +AG+ P++++EDGFET F VN L F + +LL L RVV +S ++ + +N +L S + Y+ +Y S L ++ + +L+ + + HPG V T++ R+ +P+ + W + F +T Q A T + S SG YF +
Sbjct: 134 RLDVLVNNAGVFRCPYALTEDGFETQFGVNHLGHFLLTALLLPLL---GRSAPSRVVVVSSALYKQGR-INFDDL-ASERSYDPAAAYGRSKLANVMFARELARRLRGQGVTAN------ALHPG--VVRTNLGRHVSMPALARPLFNLLAW--AAF-RTPEQGARTAVFLAASPDVADVSGAYFGD 304
BLAST of WW domain-containing oxidoreductase vs. Ensembl Yeast
Match: ENV9 (Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing and defects in vacuolar morphology; has similarity to oxidoreductases, found in lipid particles; required for replication of Brome mosaic virus in S. cerevisiae, a model system for studying replication of positive-strand RNA viruses in their natural hosts [Source:SGD;Acc:S000005772]) HSP 1 Score: 50.447 bits (119), Expect = 8.378e-7 Identity = 52/194 (26.80%), Postives = 83/194 (42.78%), Query Frame = 3
Query: 549 EIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYN-----GFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQ---PILKFIFWFFSP-----FTKTLSQAAATPILCCISN--SFKSFSGCYFNNG 1085
ID++V +AGIM+ P +++DGFE Q N +S F LL L + R++ LS H E +L+ + +Y ++ YA+S I K +K+ + C HPG +V NT++ Y PI+ FW F + Q + + C + S + +G YF G
Sbjct: 117 HIDVLVNNAGIMAVPLEMTKDGFEVQLQTNYISHFIFTMRLLPLL----RHCRGRIISLSSIGHHL--EFMYWKLS-KTWDYKPNMLFTWFRYAMSKTALIQCTKMLAIKYPDVLC------LSVHPG-LVMNTNLFSYWTRLPIVGIFFWLLFQVVGFFFGVSNEQGSLASLKCALDPNLSVEKDNGKYFTTG 296
BLAST of WW domain-containing oxidoreductase vs. Ensembl Nematostella
Match: EDO32533 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUS7]) HSP 1 Score: 76.6406 bits (187), Expect = 1.140e-23 Identity = 60/220 (27.27%), Postives = 98/220 (44.55%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR-----AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKY--SKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYLTTKINQIK 1175
+K + ++V +AG++ P+ + D E +F VN L F + ++L L S R+V LS ESHR +L++ + S +Y+ +Y S LC I++ +L + + C+ HPGN++Y TS+ IF F KT QAA+T + C +S G YF N C+P++ LW + +K
Sbjct: 209 KKSMPLHVLVCNAGVLGGPWRCTGDNIEYTFAVNYLGHFLLIKLLQDVLCS---SSPARIVMLSSESHRFQDLNYSDKLHISTVPLSRDKYHSILAYNQSKLCSIMLSMELNRRLSSEGVTCN------AVHPGNLIY-TSLYGKSWCYWLIFRIARLFAKTPEQAASTVVYCAVSPELNGVGGQYFINCRPCEPSVEAADPDKARALWTLSERLVTSLK 418 HSP 2 Score: 53.1434 bits (126), Expect = 1.140e-23 Identity = 39/150 (26.00%), Postives = 62/150 (41.33%), Query Frame = 2
Query: 116 SDTESEYELPPGW-TKSINNGTIIYNNHIINISQLYSP----LRDI-----------KIHKSDVCYEKIRYNKSCGFRPPKERHK-----RFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKC 502
S +S+ ELP W ++ + G + Y NH+ +Q P +R + K DV Y N F P+ + QK+D+ ST+ V+ NL + +V G SGIGL S L +++ C ++ K
Sbjct: 23 SSQDSDEELPVEWEVRTTDTGRVYYANHLTKTTQWQHPKTGKIRKVTGALPPGWLKQSDGKGDVFYINT-VNHQTTFTDPRSSKESTSCINISQKYDASSTTYDVLKDENLDGRVVMVTGASSGIGLATASALAAHGAHVVMACRDMEKA 171
BLAST of WW domain-containing oxidoreductase vs. Ensembl Nematostella
Match: EDO36070 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJM9]) HSP 1 Score: 80.4925 bits (197), Expect = 9.493e-18 Identity = 60/209 (28.71%), Postives = 97/209 (46.41%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSP----FTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWN 1145
+K +D+++ +AG+ PF +EDGFE F VN LS F + L R++ +S +SH E++ + N S+ Y+ YA S L +L + +LK D + HPG ++ T + R P KFI F P F K+L Q A T I C +S + +G Y+++ + +P+ Q + LW+
Sbjct: 112 KKEERVDILMNNAGVAWIPFKRTEDGFEMMFGVNHLSHFL---LTNLLLDKLKRSAPSRIINVSSKSHLFTSEIDFVDWNDESK-YSMLSRYANSKLANVLFARELAKRLK------DTGVTTYSLHPGTIM--TDLGRDIPGGKFIKVFLWPIQKVFFKSLEQGAQTQICCAVSEEHANETGLYYDDCQVTEPSKAAQDDEAAKKLWD 308 HSP 2 Score: 29.261 bits (64), Expect = 9.493e-18 Identity = 13/39 (33.33%), Postives = 19/39 (48.72%), Query Frame = 2
Query: 377 ANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNL 493
A L K ++ G +GIG E L + +I+G NL
Sbjct: 33 ARLDGKTVIITGATTGIGKETAVDLAKRGARVIIGARNL 71
BLAST of WW domain-containing oxidoreductase vs. Ensembl Nematostella
Match: EDO47050 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNF1]) HSP 1 Score: 55.8398 bits (133), Expect = 3.936e-8 Identity = 49/190 (25.79%), Postives = 87/190 (45.79%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVK---CRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILK---FIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNN 1082
Q +++++V +AG+M P+++++DGFE Q+ + + +L +G K R+V +S +H + +N +L S + Y+ F +YA + + +L +L DS L HPG V NT + R+ P + +F +P Q AAT + C+S + G Y N
Sbjct: 90 QSENQLNVLVNNAGVMLTPYALTKDGFEQ--QIGICHFGHFLLTMLLLDTLKKSGTKDCHSRIVTVSSTAHSS-GSINFEDLQ-SKKSYSRFGAYAQAKVANVLFTYALQRRLSIDSTHVTANAL----HPG--VVNTELFRHLPWIARAPMGLFFLTP-----EQGAATSLYACLSPDLEGVGGKYLAN 264
BLAST of WW domain-containing oxidoreductase vs. Ensembl Medaka
Match: wdr91 (WD repeat domain 91 [Source:NCBI gene;Acc:101167587]) HSP 1 Score: 128.257 bits (321), Expect = 6.661e-30 Identity = 161/727 (22.15%), Postives = 308/727 (42.37%), Query Frame = 1
Query: 1354 YIKQILSIKEYKNTLHSFFEEEKIDRPKK-KSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWXXXXXXXXXXXXXQVVRSV--MSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNAGKSQIISQVISNLHGSGRTLHDVSDLLCDF-RLTRENKQIEYRRASKSNKPKG---ISLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSNQSSPNLADLDNSVSMIENSINSTVIGNIAPQASSEINKNS-SADSFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXX--XXXXXXXXXALP---HGVISLYDAESWSAIQTNLITLKSD-FTVNCMYC--SSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFD-----VRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKI-NGTTLLDSVYLNAGHNSPVICID 3468
++++ L + + NTL E K D+ K + ++ LQ +Q+ DL SL + W + F L+ + T + +++ +++ +++ + EK FFQ L + EW DWF P + P ++ YF+R W D F +S+ NF + + V + +D++++ SL E Q+ + T+S K G G TLH + + + RL + +RA + P S + +++ + ++P A+ G+ K E +Q++ ++++ E AP+ ++ + + + ++Q K+SQ+ + EH S + H + S ASLDV G K+W+ N P ++ T+ K + S +W ++ ++LLGT G+V++YD + + EM ID PRI + S S FVC + S S S +ALP G + L+D + + Q +L+ D +NC + N + G ++G I+L D++ E + S +G EV +V ++D N ++ + + ++ V+ + +P++++ FV+ Y G + + PR L A+ + + + + G L+ ++ +G L+ V GH +PV+ +D
Sbjct: 11 HVREYLIYRGFTNTLKHLDHEIKADKEKGFRVDKMIEQLQQFVQSFDLFSLKEYWLYLDRRLFCRLEDVYKSTVNKLRTSLYRYYVINTIQRGNLEKTQEFFQKQ-ALELQGQPEWRDWFMLPFLPAPEQNPAIAPYFSRQWADTFLVSLHNFLSVLFQCVHILHFDAEVQRMTSLTEENEQLQQQLFAMQ----------TESRDPKD-----------GEGVTLHKLPPYVQNMDRLGDTEDLVSSQRAVSTTTPPSRNFFSTFLPQGRRTSGKTPQMTSGSLP---SHPSGARKEPSAGQVKAN-GGFMETLSQTAKRRGEMEDVEPPAETPFK-------APEGTNSCSSGAETGGGLSVEQAFIKLSQEEYG----------------EHHSSIMHCRVD-CSGRRVASLDVDGVIKVWSFN-PVMQTKATIMSKSPLLSLEWATKPDRLLLLGTGVGTVRLYDTDAKKNLYEMNIDETHPRILSLACSPSGSSFVCSAAALGGSGSVESAAALPAPVSGQLLLWDTK--TVKQQLQFSLEPDPVAINCTAFNHNGNLLVTGAADGVIRLFDMQRLE--SAMSWRAHDG-EVYSV---------EFSYDENTVLSIGEDGKFVQWNIHRCGVKQSEQVLPQDAT--GPFVL------SGYSGYKQVQVPRGRLF--AFDSEGQHVLTCSSTGGLIYRLTSGEPALERVLSLGGHKAPVVTVD 662
BLAST of WW domain-containing oxidoreductase vs. Ensembl Medaka
Match: wwox (WW domain containing oxidoreductase [Source:NCBI gene;Acc:101170267]) HSP 1 Score: 98.9821 bits (245), Expect = 2.295e-21 Identity = 62/206 (30.10%), Postives = 103/206 (50.00%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWN 1145
+ ++V +A + + P++++EDG E++FQ+ L F + + L L RVV +S ESHR + +++L L+P +EY +Y + LC IL + +L + + HPGN++Y TSI R ++ F+F PFTK++ Q AAT + C ++ + G YFNN C P+ Q + LW
Sbjct: 201 LHILVCNAAVCTQPWTLTEDGLESTFQICHLGHFLLVQCLQEVL---RRSAPARVVVVSSESHRFTDLLDSSGKVDLALLSPPRKEYWSMLAYNRAKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-TSIHRSWWLMTFLFTLARPFTKSMQQGAATTVYCAVAQELEGLGGMYFNNCFRCQPSNQAQDPSSAASLWE 396
BLAST of WW domain-containing oxidoreductase vs. Ensembl Medaka
Match: rdh12l (retinol dehydrogenase 12 [Source:NCBI gene;Acc:101168330]) HSP 1 Score: 69.707 bits (169), Expect = 2.664e-12 Identity = 53/200 (26.50%), Postives = 91/200 (45.50%), Query Frame = 3
Query: 549 EIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRY-QPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWN 1145
++++++ +AG+M P+ + DGFE VN L F + +L+ + R+V +S +H A +NL +LN S + Y+ +YA S L +L + + + + HPG V T + R+ +F PFTK Q A T I C + S + SG Y+++ + G+ E LW+
Sbjct: 99 KLNILINNAGVMVCPYGKTADGFEMQIGVNHLGHFLLTYLLIDLI---KRSAPARIVTVSSMAH-AWGSINLDDLN-SEKSYSKSKAYAQSKLANVLFTRSLAKRLEGTGV----TAYSLHPG--VVQTDLWRHLSAPEQFFMKIARPFTKNSLQGAQTTIYCAVEPSLDTESGGYYSDCAAASCSSAGKDDTVAEKLWD 287
BLAST of WW domain-containing oxidoreductase vs. Ensembl Medaka
Match: rdh12 (retinol dehydrogenase 12 [Source:NCBI gene;Acc:101164605]) HSP 1 Score: 70.4774 bits (171), Expect = 3.562e-12 Identity = 55/206 (26.70%), Postives = 95/206 (46.12%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLL---GQSKINGEMLWN 1145
++ ++ +++ +AG+M P++ + DGFE VN L F + +L+ L R+V +S +H + +L+ S YN +Y S L +L + + + D + HPG V N+ +TR+ I+ +F FS F KT + A T I C + S SG +F++ C P + G+S LW+
Sbjct: 163 REVHQLHILINNAGVMMCPYTKTVDGFEMHIGVNHLGHFLLTYLLVGLL---KRSAPARIVVVSSLAHN-FGWIRFHDLH-SQGSYNSGLAYCQSKLANVLFARELARRLNGTDVTVNSV----HPGTV--NSDLTRHSTIMTILFSVFSVFLKTPREGAQTSIYCATAEELHSISGKHFSD---CSPAFVAPQGRSSETARKLWD 354
BLAST of WW domain-containing oxidoreductase vs. Ensembl Medaka
Match: wwox (WW domain containing oxidoreductase [Source:NCBI gene;Acc:101170267]) HSP 1 Score: 67.0106 bits (162), Expect = 5.732e-11 Identity = 47/160 (29.38%), Postives = 82/160 (51.25%), Query Frame = 3
Query: 552 IDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHR------AIKELNLCELNPSSQEYNGFYSYALSSLCKILIVK--YSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLS 1007
+ ++V +A + + P++++EDG E++FQ+ L F + + L L RVV +S ESHR + +++L L+P +EY +Y + LC IL + +L + + HPGN++Y TSI R ++ F+F PFTK++
Sbjct: 201 LHILVCNAAVCTQPWTLTEDGLESTFQICHLGHFLLVQCLQEVL---RRSAPARVVVVSSESHRFTDLLDSSGKVDLALLSPPRKEYWSMLAYNRAKLCNILFSNELHRRLSPRGVTSN------AVHPGNMMY-TSIHRSWWLMTFLFTLARPFTKSMD 350
BLAST of WW domain-containing oxidoreductase vs. Planmine SMEST
Match: SMESG000077648.1 (SMESG000077648.1) HSP 1 Score: 1467.6 bits (3798), Expect = 0.000e+0 Identity = 743/743 (100.00%), Postives = 743/743 (100.00%), Query Frame = 1
Query: 1339 MNEKSYIKQILSIKEYKNTLHSFFEEEKIDRPKKKSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWXXXXXXXXXXXXXQVVRSVMSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNAGKSQIISQVISNLHGSGRTLHDVSDLLCDFRLTRENKQIEYRRASKSNKPKGISLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSNQSSPNLADLDNSVSMIENSINSTVIGNIAPQASSEINKNSSADSFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXXXALPHGVISLYDAESWSAIQTNLITLKSDFTVNCMYCSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKINGTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTISTIRINSASN 3567
MNEKSYIKQILSIKEYKNTLHSFFEEEKIDRPKKKSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWFDNFFLSMFNFFMQVVRSVMSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNAGKSQIISQVISNLHGSGRTLHDVSDLLCDFRLTRENKQIEYRRASKSNKPKGISLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSNQSSPNLADLDNSVSMIENSINSTVIGNIAPQASSEINKNSSADSFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCESLDRSRSTSSNSALPHGVISLYDAESWSAIQTNLITLKSDFTVNCMYCSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKINGTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTISTIRINSASN
Sbjct: 1 MNEKSYIKQILSIKEYKNTLHSFFEEEKIDRPKKKSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWFDNFFLSMFNFFMQVVRSVMSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNAGKSQIISQVISNLHGSGRTLHDVSDLLCDFRLTRENKQIEYRRASKSNKPKGISLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSNQSSPNLADLDNSVSMIENSINSTVIGNIAPQASSEINKNSSADSFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCESLDRSRSTSSNSALPHGVISLYDAESWSAIQTNLITLKSDFTVNCMYCSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKINGTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTISTIRINSASN 743
BLAST of WW domain-containing oxidoreductase vs. Planmine SMEST
Match: SMESG000077648.1 (SMESG000077648.1) HSP 1 Score: 825.854 bits (2132), Expect = 0.000e+0 Identity = 415/415 (100.00%), Postives = 415/415 (100.00%), Query Frame = 1
Query: 2323 MIENSINSTVIGNIAPQASSEINKNSSADSFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCEXXXXXXXXXXXXALPHGVISLYDAESWSAIQTNLITLKSDFTVNCMYCSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKINGTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTISTIRINSASN 3567
MIENSINSTVIGNIAPQASSEINKNSSADSFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCESLDRSRSTSSNSALPHGVISLYDAESWSAIQTNLITLKSDFTVNCMYCSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKINGTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTISTIRINSASN
Sbjct: 1 MIENSINSTVIGNIAPQASSEINKNSSADSFGIKQFSSKISQKIFKPKLSITTTAPKVTVFHEHFSMVTHVKCSRISNSYWASLDVGGTFKIWAINDPSCKSLHTLSFKHTIYSFDWVSQTPNMMLLGTKGGSVKMYDVTKNEIVKEMMIDLAFPRINIVQSFDSESKFVCESLDRSRSTSSNSALPHGVISLYDAESWSAIQTNLITLKSDFTVNCMYCSSNTIFAGCSNGSIKLIDIRVPENYNTNSLSIFEGDEVINVSSMCRSKWSRSNFDPNYLICVSSKSQLKIFDVRNFSKSIPKESSHLNDFVIPLSWAEKPYGGEQTIYFPRANLISAAYLNNTNTLFSAAKKGILVQKINGTTLLDSVYLNAGHNSPVICIDSYPYDLEDSDNVVVLSGTMEGTISTIRINSASN 415
BLAST of WW domain-containing oxidoreductase vs. Planmine SMEST
Match: SMESG000077648.1 (SMESG000077648.1) HSP 1 Score: 639.417 bits (1648), Expect = 0.000e+0 Identity = 327/327 (100.00%), Postives = 327/327 (100.00%), Query Frame = 1
Query: 1339 MNEKSYIKQILSIKEYKNTLHSFFEEEKIDRPKKKSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWXXXXXXXXXXXXXQVVRSVMSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNAGKSQIISQVISNLHGSGRTLHDVSDLLCDFRLTRENKQIEYRRASKSNKPKGISLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSNQSSPNLADLDNSV 2319
MNEKSYIKQILSIKEYKNTLHSFFEEEKIDRPKKKSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWFDNFFLSMFNFFMQVVRSVMSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNAGKSQIISQVISNLHGSGRTLHDVSDLLCDFRLTRENKQIEYRRASKSNKPKGISLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSNQSSPNLADLDNSV
Sbjct: 1 MNEKSYIKQILSIKEYKNTLHSFFEEEKIDRPKKKSRYFVDILQNAIQTNDLDSLIKIWKEYEILYFKFLDFDKQKTADIMKSDMFKAFLVECFKNKKTEKVNIFFQTMGTYMLTSRNEWADWFEFPLVKNPSEHKVFGIYFTRLWFDNFFLSMFNFFMQVVRSVMSYDSDLENYFSLDMRLENCINQITTKEPDMIKQKYNLTDSNAGKSQIISQVISNLHGSGRTLHDVSDLLCDFRLTRENKQIEYRRASKSNKPKGISLIIQNKTKSTSPNTFLRKKAVPFINVENVDAKDIIWKGEAKDTLTKIDEQSNQSSPNLADLDNSV 327
BLAST of WW domain-containing oxidoreductase vs. Planmine SMEST
Match: SMESG000077649.1 (SMESG000077649.1) HSP 1 Score: 408.297 bits (1048), Expect = 5.769e-132 Identity = 205/220 (93.18%), Postives = 205/220 (93.18%), Query Frame = 3
Query: 537 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFSGCYFNNGCICDPTLLGQSKINGEMLWNYLTTKINQIKIVNQKLN 1196
QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFS GQSKINGEMLWNYLTTKINQIKIVNQKLN
Sbjct: 170 QKFREIDLIVFSAGIMSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCESHRAIKELNLCELNPSSQEYNGFYSYALSSLCKILIVKYSKLKWDSIDCDRKPLFFVCHPGNVVYNTSITRYQPILKFIFWFFSPFTKTLSQAAATPILCCISNSFKSFS---------------GQSKINGEMLWNYLTTKINQIKIVNQKLN 374 HSP 2 Score: 287.73 bits (735), Expect = 3.772e-87 Identity = 143/154 (92.86%), Postives = 146/154 (94.81%), Query Frame = 2
Query: 110 MESDTESEYELPPGWTKSINNGTIIYNNHIINISQLYSPLRDIKIHKSDVCYEKIRYNKSCGFRPPKERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTKISGNRFDSFQ 571
MESDTESEYELPPGWTKSINNGTIIYNNHIINISQLYSPLRDIKIHKSDVCYEKIRYNKSCGFRPPKERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKL + +I N + FQ
Sbjct: 1 MESDTESEYELPPGWTKSINNGTIIYNNHIINISQLYSPLRDIKIHKSDVCYEKIRYNKSCGFRPPKERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLGN--EIVTNFINIFQ 152
BLAST of WW domain-containing oxidoreductase vs. Planmine SMEST
Match: SMESG000077649.1 (SMESG000077649.1) HSP 1 Score: 349.747 bits (896), Expect = 5.846e-113 Identity = 169/169 (100.00%), Postives = 169/169 (100.00%), Query Frame = 2
Query: 110 MESDTESEYELPPGWTKSINNGTIIYNNHIINISQLYSPLRDIKIHKSDVCYEKIRYNKSCGFRPPKERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTKISGNRFDSFQRWHYEPTIFSFRGWI 616
MESDTESEYELPPGWTKSINNGTIIYNNHIINISQLYSPLRDIKIHKSDVCYEKIRYNKSCGFRPPKERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTKISGNRFDSFQRWHYEPTIFSFRGWI
Sbjct: 1 MESDTESEYELPPGWTKSINNGTIIYNNHIINISQLYSPLRDIKIHKSDVCYEKIRYNKSCGFRPPKERHKRFIQKFDSFSTSEQVINTANLSFKRALVIGGCSGIGLEIVSQLITKNCMIILGCPNLIKCDLELKSKLVDFTKISGNRFDSFQRWHYEPTIFSFRGWI 169 The following BLAST results are available for this feature:
BLAST of WW domain-containing oxidoreductase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of WW domain-containing oxidoreductase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of WW domain-containing oxidoreductase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of WW domain-containing oxidoreductase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of WW domain-containing oxidoreductase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30006610 ID=SMED30006610|Name=WW domain-containing oxidoreductase|organism=Schmidtea mediterranea sexual|type=transcript|length=3641bpback to top protein sequence of SMED30006610-orf-1 >SMED30006610-orf-1 ID=SMED30006610-orf-1|Name=SMED30006610-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=170bp MESDTESEYELPPGWTKSINNGTIIYNNHIINISQLYSPLRDIKIHKSDVback to top protein sequence of SMED30006610-orf-2 >SMED30006610-orf-2 ID=SMED30006610-orf-2|Name=SMED30006610-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=746bp MNEKSYIKQILSIKEYKNTLHSFFEEEKIDRPKKKSRYFVDILQNAIQTNback to top protein sequence of SMED30006610-orf-3 >SMED30006610-orf-3 ID=SMED30006610-orf-3|Name=SMED30006610-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=206bp MSPPFSVSEDGFETSFQVNVLSLFYIQEMLLSSLFSPHNGVKCRVVWLSCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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