RAN binding protein 2

Overview
NameRAN binding protein 2
Smed IDSMED30006518
Length (bp)773
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RAN binding protein 2 (SMED30006518) t-SNE clustered cells

Violin plots show distribution of expression levels for RAN binding protein 2 (SMED30006518) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RAN binding protein 2 (SMED30006518) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RAN binding protein 2 (SMED30006518) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30006518

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30006518h1SMcG0004305 SmedASXL_017694SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30006518h1SMcG0004305 SmedASXL_017695SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30006518h1SMcG0004305 Contig37558uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006518h1SMcG0004305 Contig37558newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
neoblastSMED30006518h1SMcG0004305 dd_Smed_v4_8023_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30006518h1SMcG0004305 dd_Smed_v4_8646_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of RAN binding protein 2 vs. Ensembl Human
Match: RANBP2 (RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9848])

HSP 1 Score: 112.464 bits (280), Expect = 2.188e-27
Identity = 61/153 (39.87%), Postives = 96/153 (62.75%), Query Frame = 1
Query:  325 DDEGENPE---NFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            D++G + E   N +  ++PI+SLPEVE  +GEE+ E LF ER KLY+W    ++WKERG+G++KIL     N   YR++MRR+QV KV  NH I +       +  +  +  W A D+++G   V E+ A++FKT+E+ + FK T ++ Q+ +
Sbjct: 2896 DEDGSDEEVVHNEDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDVSQWKERGVGDIKILWHTMKN--YYRILMRRDQVFKVCANHVITKTM-ELKPLNVSNNALVWTASDYADGEAKV-EQLAVRFKTKEVADCFKKTFEECQQNL 3044          

HSP 2 Score: 102.064 bits (253), Expect = 8.397e-24
Identity = 58/152 (38.16%), Postives = 92/152 (60.53%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +DD  +  ++ +  ++P++ +PE VE +TGEE+ + L+S+R KL+++  E   WKERGLG +KIL ++ + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q  +
Sbjct: 1999 DDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRVKLFRFDAEVSQWKERGLGNLKILKNEVNGK--LRMLMRREQVLKVCANHWITTTM-NLKPLSGSDRAWMWLASDFSDGDAKL-EQLAAKFKTPELAEEFKQKFEECQRLL 2146          

HSP 3 Score: 93.9745 bits (232), Expect = 3.992e-21
Identity = 56/140 (40.00%), Postives = 86/140 (61.43%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R KLY++     +WKERG+G++KIL +  DNK+  R+VMRR+QV K+  NH I  +     +M   +    W A DF++G   V E  A++FK +++ + FK   D  K  QEK
Sbjct: 2310 FEPVVPLPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDIKILQN-YDNKQ-VRIVMRRDQVLKLCANHRITPDM-TLQNMKGTERVWLWTACDFADGERKV-EHLAVRFKLQDVADSFKKIFDEAKTAQEK 2445          

HSP 4 Score: 92.8189 bits (229), Expect = 1.090e-20
Identity = 58/138 (42.03%), Postives = 84/138 (60.87%), Query Frame = 1
Query:  358 PDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQ 756
            P ++P++ LP+ +E  TGEE+ E  F  R KL+++   S EWKERG+G +KIL  KT  K   RL+MRREQV K+  NH I  +     + G+++ S  W A D+++  EL K E+ AI+FKT E    FK   ++ Q
Sbjct: 1170 PHFEPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDVESKEWKERGIGNVKILRHKTSGK--IRLLMRREQVLKICANHYISPDMKLTPNAGSDR-SFVWHALDYAD--ELPKPEQLAIRFKTPEEAALFKCKFEEAQ 1302          
BLAST of RAN binding protein 2 vs. Ensembl Human
Match: RGPD8 (RANBP2 like and GRIP domain containing 8 [Source:HGNC Symbol;Acc:HGNC:9849])

HSP 1 Score: 98.9821 bits (245), Expect = 8.762e-23
Identity = 57/152 (37.50%), Postives = 90/152 (59.21%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +DD  +  ++ +  ++P++ +PE VE +TGEE  + L+S+  KL+++  E   WKERGLG +KIL ++ + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q  +
Sbjct: 1023 DDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGK--LRMLMRREQVLKVCANHWITTTM-NLKPLSGSDRAWMWSASDFSDGDAKL-ERLAAKFKTPELAEEFKQKFEECQRLL 1170          

HSP 2 Score: 92.4337 bits (228), Expect = 1.603e-20
Identity = 54/140 (38.57%), Postives = 87/140 (62.14%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R ++Y++     +WKERG+G++KIL +  DNK+  R+VMRR+QV K+  NH I  +  +  +M   +    W A DF++G   V E  A++FK +++ + FK   D  K  QEK
Sbjct: 1334 FEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQN-YDNKQ-VRIVMRRDQVLKLCANHRITPDM-SLQNMKGTERVWVWTACDFADGERKV-EHLAVRFKLQDVADSFKKIFDEAKTAQEK 1469          
BLAST of RAN binding protein 2 vs. Ensembl Human
Match: RGPD6 (RANBP2 like and GRIP domain containing 6 [Source:HGNC Symbol;Acc:HGNC:32419])

HSP 1 Score: 98.9821 bits (245), Expect = 8.930e-23
Identity = 57/152 (37.50%), Postives = 90/152 (59.21%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +DD  +  ++ +  ++P++ +PE VE +TGEE  + L+S+  KL+++  E   WKERGLG +KIL ++ + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q  +
Sbjct: 1023 DDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGK--LRMLMRREQVLKVCANHWITTTM-NLKPLSGSDRAWMWSASDFSDGDAKL-ERLAAKFKTPELAEEFKQKFEECQRLL 1170          

HSP 2 Score: 92.0485 bits (227), Expect = 1.730e-20
Identity = 54/140 (38.57%), Postives = 87/140 (62.14%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R ++Y++     +WKERG+G++KIL +  DNK+  R+VMRR+QV K+  NH I  +  +  +M   +    W A DF++G   V E  A++FK +++ + FK   D  K  QEK
Sbjct: 1334 FEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQN-YDNKQ-VRIVMRRDQVLKLCANHRITPDM-SLQNMKGTERVWVWTACDFADGERKV-EHLAVRFKLQDVADSFKKIFDEAKTAQEK 1469          
BLAST of RAN binding protein 2 vs. Ensembl Human
Match: RGPD5 (RANBP2 like and GRIP domain containing 5 [Source:HGNC Symbol;Acc:HGNC:32418])

HSP 1 Score: 98.9821 bits (245), Expect = 8.930e-23
Identity = 57/152 (37.50%), Postives = 90/152 (59.21%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +DD  +  ++ +  ++P++ +PE VE +TGEE  + L+S+  KL+++  E   WKERGLG +KIL ++ + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q  +
Sbjct: 1023 DDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGK--LRMLMRREQVLKVCANHWITTTM-NLKPLSGSDRAWMWSASDFSDGDAKL-ERLAAKFKTPELAEEFKQKFEECQRLL 1170          

HSP 2 Score: 92.0485 bits (227), Expect = 1.730e-20
Identity = 54/140 (38.57%), Postives = 87/140 (62.14%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R ++Y++     +WKERG+G++KIL +  DNK+  R+VMRR+QV K+  NH I  +  +  +M   +    W A DF++G   V E  A++FK +++ + FK   D  K  QEK
Sbjct: 1334 FEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQN-YDNKQ-VRIVMRRDQVLKLCANHRITPDM-SLQNMKGTERVWVWTACDFADGERKV-EHLAVRFKLQDVADSFKKIFDEAKTAQEK 1469          
BLAST of RAN binding protein 2 vs. Ensembl Human
Match: RGPD8 (RANBP2 like and GRIP domain containing 8 [Source:HGNC Symbol;Acc:HGNC:9849])

HSP 1 Score: 98.9821 bits (245), Expect = 9.011e-23
Identity = 57/152 (37.50%), Postives = 90/152 (59.21%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +DD  +  ++ +  ++P++ +PE VE +TGEE  + L+S+  KL+++  E   WKERGLG +KIL ++ + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q  +
Sbjct:  883 DDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGK--LRMLMRREQVLKVCANHWITTTM-NLKPLSGSDRAWMWSASDFSDGDAKL-ERLAAKFKTPELAEEFKQKFEECQRLL 1030          

HSP 2 Score: 92.4337 bits (228), Expect = 1.529e-20
Identity = 54/140 (38.57%), Postives = 87/140 (62.14%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R ++Y++     +WKERG+G++KIL +  DNK+  R+VMRR+QV K+  NH I  +  +  +M   +    W A DF++G   V E  A++FK +++ + FK   D  K  QEK
Sbjct: 1194 FEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQN-YDNKQ-VRIVMRRDQVLKLCANHRITPDM-SLQNMKGTERVWVWTACDFADGERKV-EHLAVRFKLQDVADSFKKIFDEAKTAQEK 1329          
BLAST of RAN binding protein 2 vs. Ensembl Celegans
Match: npp-9 (Nuclear Pore complex Protein [Source:UniProtKB/TrEMBL;Acc:Q86G90])

HSP 1 Score: 96.6709 bits (239), Expect = 1.533e-22
Identity = 54/129 (41.86%), Postives = 81/129 (62.79%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSN---EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            +++P+I LP+ VE  TGEE  + +F  R KLY ++N   EWKERG GE+K+L +K  +KKS+R+VMRR+QV KV  N  I+ +      M +N+ +  WF EDFSE  +    K + +F   ++  +FK
Sbjct:  254 EFKPVIPLPDLVEVKTGEEGEQTMFCNRSKLYIYANETKEWKERGTGELKVLYNK--DKKSWRVVMRRDQVLKVCANFPILGSM-TIQQMKSNEKAYTWFCEDFSE-DQPAHVKLSARFANVDIAGEFK 378          

HSP 2 Score: 95.1301 bits (235), Expect = 5.902e-22
Identity = 62/145 (42.76%), Postives = 85/145 (58.62%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSNEW---KERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNC-----PNFSDMGANKTSACW-FAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +++P+I LP+ VE  TGEE+ E +FS RCKLYK+ ++    KERGLG++K+L S  DNK  YR+VMRREQV K+  N  I ++      PN  ++    T  C  F+ED S     +   F  KFK E     FK  ++D Q KM
Sbjct:  725 EFKPVIPLPDLVEVKTGEEDEEVMFSARCKLYKYYSDLKENKERGLGDIKLLKS-NDNK--YRIVMRREQVHKLCANFRIEKSMKLSPKPNLPNV---LTFMCQDFSEDASNADPAI---FTAKFKDEATAGAFKTAVQDAQSKM 860          
BLAST of RAN binding protein 2 vs. Ensembl Celegans
Match: npp-9 (Nuclear Pore complex Protein [Source:UniProtKB/TrEMBL;Acc:Q86G90])

HSP 1 Score: 96.6709 bits (239), Expect = 1.533e-22
Identity = 54/129 (41.86%), Postives = 81/129 (62.79%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSN---EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            +++P+I LP+ VE  TGEE  + +F  R KLY ++N   EWKERG GE+K+L +K  +KKS+R+VMRR+QV KV  N  I+ +      M +N+ +  WF EDFSE  +    K + +F   ++  +FK
Sbjct:  254 EFKPVIPLPDLVEVKTGEEGEQTMFCNRSKLYIYANETKEWKERGTGELKVLYNK--DKKSWRVVMRRDQVLKVCANFPILGSM-TIQQMKSNEKAYTWFCEDFSE-DQPAHVKLSARFANVDIAGEFK 378          

HSP 2 Score: 95.1301 bits (235), Expect = 5.902e-22
Identity = 62/145 (42.76%), Postives = 85/145 (58.62%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSNEW---KERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNC-----PNFSDMGANKTSACW-FAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +++P+I LP+ VE  TGEE+ E +FS RCKLYK+ ++    KERGLG++K+L S  DNK  YR+VMRREQV K+  N  I ++      PN  ++    T  C  F+ED S     +   F  KFK E     FK  ++D Q KM
Sbjct:  725 EFKPVIPLPDLVEVKTGEEDEEVMFSARCKLYKYYSDLKENKERGLGDIKLLKS-NDNK--YRIVMRREQVHKLCANFRIEKSMKLSPKPNLPNV---LTFMCQDFSEDASNADPAI---FTAKFKDEATAGAFKTAVQDAQSKM 860          
BLAST of RAN binding protein 2 vs. Ensembl Celegans
Match: npp-9 (Nuclear Pore complex Protein [Source:UniProtKB/TrEMBL;Acc:Q86G90])

HSP 1 Score: 96.6709 bits (239), Expect = 1.533e-22
Identity = 54/129 (41.86%), Postives = 81/129 (62.79%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSN---EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            +++P+I LP+ VE  TGEE  + +F  R KLY ++N   EWKERG GE+K+L +K  +KKS+R+VMRR+QV KV  N  I+ +      M +N+ +  WF EDFSE  +    K + +F   ++  +FK
Sbjct:  254 EFKPVIPLPDLVEVKTGEEGEQTMFCNRSKLYIYANETKEWKERGTGELKVLYNK--DKKSWRVVMRRDQVLKVCANFPILGSM-TIQQMKSNEKAYTWFCEDFSE-DQPAHVKLSARFANVDIAGEFK 378          

HSP 2 Score: 95.1301 bits (235), Expect = 5.902e-22
Identity = 62/145 (42.76%), Postives = 85/145 (58.62%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSNEW---KERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNC-----PNFSDMGANKTSACW-FAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +++P+I LP+ VE  TGEE+ E +FS RCKLYK+ ++    KERGLG++K+L S  DNK  YR+VMRREQV K+  N  I ++      PN  ++    T  C  F+ED S     +   F  KFK E     FK  ++D Q KM
Sbjct:  725 EFKPVIPLPDLVEVKTGEEDEEVMFSARCKLYKYYSDLKENKERGLGDIKLLKS-NDNK--YRIVMRREQVHKLCANFRIEKSMKLSPKPNLPNV---LTFMCQDFSEDASNADPAI---FTAKFKDEATAGAFKTAVQDAQSKM 860          
BLAST of RAN binding protein 2 vs. Ensembl Celegans
Match: npp-9 (Nuclear Pore complex Protein [Source:UniProtKB/TrEMBL;Acc:Q86G90])

HSP 1 Score: 94.7449 bits (234), Expect = 7.681e-22
Identity = 62/145 (42.76%), Postives = 85/145 (58.62%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSNEW---KERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNC-----PNFSDMGANKTSACW-FAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +++P+I LP+ VE  TGEE+ E +FS RCKLYK+ ++    KERGLG++K+L S  DNK  YR+VMRREQV K+  N  I ++      PN  ++    T  C  F+ED S     +   F  KFK E     FK  ++D Q KM
Sbjct:  749 EFKPVIPLPDLVEVKTGEEDEEVMFSARCKLYKYYSDLKENKERGLGDIKLLKS-NDNK--YRIVMRREQVHKLCANFRIEKSMKLSPKPNLPNV---LTFMCQDFSEDASNADPAI---FTAKFKDEATAGAFKTAVQDAQSKM 884          

HSP 2 Score: 87.0409 bits (214), Expect = 3.587e-19
Identity = 54/152 (35.53%), Postives = 85/152 (55.92%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSN---EWKERGLGEMKILASKTDNKKSYRLVMRREQV---------------RKVVCNHAIVQNCPNFSDMG--------ANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            +++P+I LP+ VE  TGEE  + +F  R KLY ++N   EWKERG GE+K+L +K  +KKS+R+VMRR+QV                ++  N  +++ C NF  +G        +N+ +  WF EDFSE  +    K + +F   ++  +FK
Sbjct:  254 EFKPVIPLPDLVEVKTGEEGEQTMFCNRSKLYIYANETKEWKERGTGELKVLYNK--DKKSWRVVMRRDQVTISEETLPSNIENGTEELCWNIQVLKVCANFPILGSMTIQQMKSNEKAYTWFCEDFSE-DQPAHVKLSARFANVDIAGEFK 402          
BLAST of RAN binding protein 2 vs. Ensembl Celegans
Match: npp-9 (Nuclear Pore complex Protein [Source:UniProtKB/TrEMBL;Acc:Q86G90])

HSP 1 Score: 94.7449 bits (234), Expect = 7.681e-22
Identity = 62/145 (42.76%), Postives = 85/145 (58.62%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSNEW---KERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNC-----PNFSDMGANKTSACW-FAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +++P+I LP+ VE  TGEE+ E +FS RCKLYK+ ++    KERGLG++K+L S  DNK  YR+VMRREQV K+  N  I ++      PN  ++    T  C  F+ED S     +   F  KFK E     FK  ++D Q KM
Sbjct:  749 EFKPVIPLPDLVEVKTGEEDEEVMFSARCKLYKYYSDLKENKERGLGDIKLLKS-NDNK--YRIVMRREQVHKLCANFRIEKSMKLSPKPNLPNV---LTFMCQDFSEDASNADPAI---FTAKFKDEATAGAFKTAVQDAQSKM 884          

HSP 2 Score: 87.0409 bits (214), Expect = 3.587e-19
Identity = 54/152 (35.53%), Postives = 85/152 (55.92%), Query Frame = 1
Query:  361 DYQPIISLPE-VETITGEENSECLFSERCKLYKWSN---EWKERGLGEMKILASKTDNKKSYRLVMRREQV---------------RKVVCNHAIVQNCPNFSDMG--------ANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            +++P+I LP+ VE  TGEE  + +F  R KLY ++N   EWKERG GE+K+L +K  +KKS+R+VMRR+QV                ++  N  +++ C NF  +G        +N+ +  WF EDFSE  +    K + +F   ++  +FK
Sbjct:  254 EFKPVIPLPDLVEVKTGEEGEQTMFCNRSKLYIYANETKEWKERGTGELKVLYNK--DKKSWRVVMRRDQVTISEETLPSNIENGTEELCWNIQVLKVCANFPILGSMTIQQMKSNEKAYTWFCEDFSE-DQPAHVKLSARFANVDIAGEFK 402          
BLAST of RAN binding protein 2 vs. Ensembl Fly
Match: Nup358 (gene:FBgn0039302 transcript:FBtr0084813)

HSP 1 Score: 110.923 bits (276), Expect = 3.650e-27
Identity = 56/138 (40.58%), Postives = 87/138 (63.04%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            + P+I+LP+ VE +TGEEN + LF  R KL +W   +NEWKERGLG MK+L  +TD  K  RL+MRREQV K+ CN  ++     F+     K +  W A+D+S+  EL     A++FK++++  +F + ++  Q+ +
Sbjct: 1606 FVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNK-VRLLMRREQVHKLCCNQRLLPET-KFTYATNCKAAVTWGAQDYSD-EELTTALLAVRFKSQDICQQFLEAVQKAQQSI 1740          

HSP 2 Score: 98.2117 bits (243), Expect = 6.322e-23
Identity = 54/129 (41.86%), Postives = 79/129 (61.24%), Query Frame = 1
Query:  358 PDYQPIISLP-EVETITGEENSECLFSERCKLYKWSN-EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCP-NFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            PD++PII LP EVE  TGEE  +  F+ R KL+++ + EWKERG G +KIL  K       R++MRR+Q  KV  NH I  +   N ++   +K S  W A DF++  ++  E+F ++FKT EL  +F+
Sbjct: 1308 PDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVDKEWKERGTGVIKILCDKATGVS--RVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFAD-EQVTLERFLVRFKTGELAEEFR 1433          

HSP 3 Score: 94.7449 bits (234), Expect = 1.234e-21
Identity = 58/147 (39.46%), Postives = 86/147 (58.50%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWS-NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWF--AEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKD 750
            ND +    E  N  + P+I LP+ ++  TGEE+ E L+  + KLY+ + ++WKERGLG++KIL  +    K  R+VMRREQV K+  NH + +N      +   KT   W     DFSEG E V E+F ++FK +E+   F + IK+
Sbjct: 2006 NDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESDWKERGLGDVKILRHR--QTKKLRVVMRREQVFKICLNHVLNENV-----VYREKTETSWMFAVHDFSEG-ESVLERFTLRFKNKEVAQGFMEAIKN 2144          

HSP 4 Score: 92.8189 bits (229), Expect = 5.163e-21
Identity = 55/142 (38.73%), Postives = 84/142 (59.15%), Query Frame = 1
Query:  349 NFNPDYQPIISLP-EVETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDF---SEG---TELVKEKFAIKFKTEELLNKFKDTI 744
            N++P Y  I+ LP E+   TGEEN   LF ER KLY++   S +WKERG+GE+K+L  +    +++RL+MR+EQ+ K+V N  I  +      M A   S  W   ++   +EG   TE V E+ A +F  EE+ ++F +T+
Sbjct: 2529 NYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVL--EHPELQTFRLIMRQEQIHKLVLNMNISASL-QMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTV 2667          
BLAST of RAN binding protein 2 vs. Ensembl Fly
Match: Nup358 (gene:FBgn0039302 transcript:FBtr0304692)

HSP 1 Score: 110.538 bits (275), Expect = 3.905e-27
Identity = 59/146 (40.41%), Postives = 90/146 (61.64%), Query Frame = 1
Query:  346 ENFNPDYQ--PIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            E + P  Q  P+I+LP+ VE +TGEEN + LF  R KL +W   +NEWKERGLG MK+L  +TD  K  RL+MRREQV K+ CN  ++     F+     K +  W A+D+S+  EL     A++FK++++  +F + ++  Q+ +
Sbjct: 1598 EEYVPTAQFVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNK-VRLLMRREQVHKLCCNQRLLPET-KFTYATNCKAAVTWGAQDYSD-EELTTALLAVRFKSQDICQQFLEAVQKAQQSI 1740          

HSP 2 Score: 98.2117 bits (243), Expect = 6.697e-23
Identity = 54/129 (41.86%), Postives = 79/129 (61.24%), Query Frame = 1
Query:  358 PDYQPIISLP-EVETITGEENSECLFSERCKLYKWSN-EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCP-NFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            PD++PII LP EVE  TGEE  +  F+ R KL+++ + EWKERG G +KIL  K       R++MRR+Q  KV  NH I  +   N ++   +K S  W A DF++  ++  E+F ++FKT EL  +F+
Sbjct: 1308 PDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVDKEWKERGTGVIKILCDKATGVS--RVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFAD-EQVTLERFLVRFKTGELAEEFR 1433          

HSP 3 Score: 94.3597 bits (233), Expect = 1.319e-21
Identity = 58/147 (39.46%), Postives = 86/147 (58.50%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWS-NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWF--AEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKD 750
            ND +    E  N  + P+I LP+ ++  TGEE+ E L+  + KLY+ + ++WKERGLG++KIL  +    K  R+VMRREQV K+  NH + +N      +   KT   W     DFSEG E V E+F ++FK +E+   F + IK+
Sbjct: 2006 NDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESDWKERGLGDVKILRHR--QTKKLRVVMRREQVFKICLNHVLNENV-----VYREKTETSWMFAVHDFSEG-ESVLERFTLRFKNKEVAQGFMEAIKN 2144          

HSP 4 Score: 92.8189 bits (229), Expect = 5.366e-21
Identity = 55/142 (38.73%), Postives = 84/142 (59.15%), Query Frame = 1
Query:  349 NFNPDYQPIISLP-EVETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDF---SEG---TELVKEKFAIKFKTEELLNKFKDTI 744
            N++P Y  I+ LP E+   TGEEN   LF ER KLY++   S +WKERG+GE+K+L  +    +++RL+MR+EQ+ K+V N  I  +      M A   S  W   ++   +EG   TE V E+ A +F  EE+ ++F +T+
Sbjct: 2552 NYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVL--EHPELQTFRLIMRQEQIHKLVLNMNISASL-QMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTV 2690          
BLAST of RAN binding protein 2 vs. Ensembl Zebrafish
Match: RANBP2 (si:ch1073-55a19.2 [Source:ZFIN;Acc:ZDB-GENE-081104-93])

HSP 1 Score: 118.242 bits (295), Expect = 1.101e-29
Identity = 64/141 (45.39%), Postives = 88/141 (62.41%), Query Frame = 1
Query:  343 PENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQ 756
            P +    ++PI+SLPEVE  +GEE+ E LF ERC+LY+W     +WKERG+GE+KIL      KKSYRL+MRREQV KV  NH I       + M ++  +  W A D++EG   V E+ A+KFK+ +L   F+   +D Q
Sbjct: 2617 PHSDEIHFEPIVSLPEVEVRSGEEDEEILFKERCRLYRWDRDLQQWKERGVGELKILFHP--QKKSYRLLMRREQVLKVCANHTISSGI-TLTHMNSSANALVWTATDYAEGDGKV-EQLAVKFKSADLAQSFRRVFEDCQ 2753          

HSP 2 Score: 100.908 bits (250), Expect = 1.158e-23
Identity = 60/164 (36.59%), Postives = 99/164 (60.37%), Query Frame = 1
Query:  286 LFPIIPQLPTLTNDDEGE---NPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQ 756
            LF ++P+ P  + D E E     EN +  ++P++ +P+ V+ +TGEE+ + L+S+R KL+++   +++WKERG+G +K+L +  + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q
Sbjct: 1756 LFTVLPK-PDTSADQEDEMYRTEENDDIQFEPVVQMPDKVDLVTGEEDEKILYSQRVKLFRFDPETSQWKERGVGNLKLLKNNQNGK--LRVLMRREQVLKVCANHWITTTM-NLKPLAGSDRAWMWLASDFSDGDARL-EQLAAKFKTPELAEEFKQRFEECQ 1914          

HSP 3 Score: 88.9669 bits (219), Expect = 1.440e-19
Identity = 55/158 (34.81%), Postives = 92/158 (58.23%), Query Frame = 1
Query:  313 TLTNDDEGENPENFNPD---YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++  DDE +  +    D   ++P++ +P+ VE  TGEE+ + LFS R KLY++    ++WKERG+G++KIL  +    K  RLVMRR+QV K+  NH I  +      M   + +  W A DF+EG   V E+ A++FK ++  + F+D  ++ +  +
Sbjct: 2054 SVGTDDEQDTSQEEERDGQYFEPVVPMPDLVEVSTGEEDEQVLFSHRAKLYRYDKTLSQWKERGIGDLKIL--QHYETKRVRLVMRRDQVLKLCANHWI-DSSMKLEPMKGAEKAWIWSAFDFAEGQGKV-EQLAVRFKLQDTASIFRDVFEEAKTAL 2207          

HSP 4 Score: 85.5001 bits (210), Expect = 2.316e-18
Identity = 59/151 (39.07%), Postives = 90/151 (59.60%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQE 759
            ND      +   P ++PI+ LP+ V+  TGEE  E +F +R KL+++   + EWKERG+G +KIL  KT  K   RL+MRREQV K+  NH I  +     + G++K S  W+A D+++  E+ K E+ AI+FKT +    FK   ++ Q+
Sbjct: 1129 NDSTHVEEDEDGPHFEPIVPLPDKVDVKTGEEEEEEMFCKRAKLFRFDADTKEWKERGIGSIKILKHKTSGK--VRLLMRREQVLKICANHYITADMALKPNAGSDK-SWVWYAMDYAD--EMPKTEQLAIRFKTADDAALFKVKFEEAQK 1274          
BLAST of RAN binding protein 2 vs. Ensembl Zebrafish
Match: RANBP2 (si:ch1073-55a19.2 [Source:ZFIN;Acc:ZDB-GENE-081104-93])

HSP 1 Score: 118.242 bits (295), Expect = 1.167e-29
Identity = 64/141 (45.39%), Postives = 88/141 (62.41%), Query Frame = 1
Query:  343 PENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQ 756
            P +    ++PI+SLPEVE  +GEE+ E LF ERC+LY+W     +WKERG+GE+KIL      KKSYRL+MRREQV KV  NH I       + M ++  +  W A D++EG   V E+ A+KFK+ +L   F+   +D Q
Sbjct: 2633 PHSDEIHFEPIVSLPEVEVRSGEEDEEILFKERCRLYRWDRDLQQWKERGVGELKILFHP--QKKSYRLLMRREQVLKVCANHTISSGI-TLTHMNSSANALVWTATDYAEGDGKV-EQLAVKFKSADLAQSFRRVFEDCQ 2769          

HSP 2 Score: 100.908 bits (250), Expect = 1.274e-23
Identity = 60/164 (36.59%), Postives = 99/164 (60.37%), Query Frame = 1
Query:  286 LFPIIPQLPTLTNDDEGE---NPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQ 756
            LF ++P+ P  + D E E     EN +  ++P++ +P+ V+ +TGEE+ + L+S+R KL+++   +++WKERG+G +K+L +  + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q
Sbjct: 1750 LFTVLPK-PDTSADQEDEMYRTEENDDIQFEPVVQMPDKVDLVTGEEDEKILYSQRVKLFRFDPETSQWKERGVGNLKLLKNNQNGK--LRVLMRREQVLKVCANHWITTTM-NLKPLAGSDRAWMWLASDFSDGDARL-EQLAAKFKTPELAEEFKQRFEECQ 1908          

HSP 3 Score: 88.9669 bits (219), Expect = 1.569e-19
Identity = 55/158 (34.81%), Postives = 92/158 (58.23%), Query Frame = 1
Query:  313 TLTNDDEGENPENFNPD---YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++  DDE +  +    D   ++P++ +P+ VE  TGEE+ + LFS R KLY++    ++WKERG+G++KIL  +    K  RLVMRR+QV K+  NH I  +      M   + +  W A DF+EG   V E+ A++FK ++  + F+D  ++ +  +
Sbjct: 2048 SVGTDDEQDTSQEEERDGQYFEPVVPMPDLVEVSTGEEDEQVLFSHRAKLYRYDKTLSQWKERGIGDLKIL--QHYETKRVRLVMRRDQVLKLCANHWI-DSSMKLEPMKGAEKAWIWSAFDFAEGQGKV-EQLAVRFKLQDTASIFRDVFEEAKTAL 2201          

HSP 4 Score: 85.5001 bits (210), Expect = 2.475e-18
Identity = 59/151 (39.07%), Postives = 90/151 (59.60%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQE 759
            ND      +   P ++PI+ LP+ V+  TGEE  E +F +R KL+++   + EWKERG+G +KIL  KT  K   RL+MRREQV K+  NH I  +     + G++K S  W+A D+++  E+ K E+ AI+FKT +    FK   ++ Q+
Sbjct: 1123 NDSTHVEEDEDGPHFEPIVPLPDKVDVKTGEEEEEEMFCKRAKLFRFDADTKEWKERGIGSIKILKHKTSGK--VRLLMRREQVLKICANHYITADMALKPNAGSDK-SWVWYAMDYAD--EMPKTEQLAIRFKTADDAALFKVKFEEAQK 1268          
BLAST of RAN binding protein 2 vs. Ensembl Zebrafish
Match: RANBP2 (si:ch1073-55a19.2 [Source:ZFIN;Acc:ZDB-GENE-081104-93])

HSP 1 Score: 118.242 bits (295), Expect = 1.236e-29
Identity = 64/141 (45.39%), Postives = 88/141 (62.41%), Query Frame = 1
Query:  343 PENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQ 756
            P +    ++PI+SLPEVE  +GEE+ E LF ERC+LY+W     +WKERG+GE+KIL      KKSYRL+MRREQV KV  NH I       + M ++  +  W A D++EG   V E+ A+KFK+ +L   F+   +D Q
Sbjct: 2634 PHSDEIHFEPIVSLPEVEVRSGEEDEEILFKERCRLYRWDRDLQQWKERGVGELKILFHP--QKKSYRLLMRREQVLKVCANHTISSGI-TLTHMNSSANALVWTATDYAEGDGKV-EQLAVKFKSADLAQSFRRVFEDCQ 2770          

HSP 2 Score: 100.908 bits (250), Expect = 1.336e-23
Identity = 60/164 (36.59%), Postives = 99/164 (60.37%), Query Frame = 1
Query:  286 LFPIIPQLPTLTNDDEGE---NPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQ 756
            LF ++P+ P  + D E E     EN +  ++P++ +P+ V+ +TGEE+ + L+S+R KL+++   +++WKERG+G +K+L +  + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q
Sbjct: 1750 LFTVLPK-PDTSADQEDEMYRTEENDDIQFEPVVQMPDKVDLVTGEEDEKILYSQRVKLFRFDPETSQWKERGVGNLKLLKNNQNGK--LRVLMRREQVLKVCANHWITTTM-NLKPLAGSDRAWMWLASDFSDGDARL-EQLAAKFKTPELAEEFKQRFEECQ 1908          

HSP 3 Score: 88.9669 bits (219), Expect = 1.629e-19
Identity = 55/158 (34.81%), Postives = 92/158 (58.23%), Query Frame = 1
Query:  313 TLTNDDEGENPENFNPD---YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++  DDE +  +    D   ++P++ +P+ VE  TGEE+ + LFS R KLY++    ++WKERG+G++KIL  +    K  RLVMRR+QV K+  NH I  +      M   + +  W A DF+EG   V E+ A++FK ++  + F+D  ++ +  +
Sbjct: 2048 SVGTDDEQDTSQEEERDGQYFEPVVPMPDLVEVSTGEEDEQVLFSHRAKLYRYDKTLSQWKERGIGDLKIL--QHYETKRVRLVMRRDQVLKLCANHWI-DSSMKLEPMKGAEKAWIWSAFDFAEGQGKV-EQLAVRFKLQDTASIFRDVFEEAKTAL 2201          

HSP 4 Score: 85.1149 bits (209), Expect = 2.570e-18
Identity = 59/151 (39.07%), Postives = 90/151 (59.60%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQE 759
            ND      +   P ++PI+ LP+ V+  TGEE  E +F +R KL+++   + EWKERG+G +KIL  KT  K   RL+MRREQV K+  NH I  +     + G++K S  W+A D+++  E+ K E+ AI+FKT +    FK   ++ Q+
Sbjct: 1123 NDSTHVEEDEDGPHFEPIVPLPDKVDVKTGEEEEEEMFCKRAKLFRFDADTKEWKERGIGSIKILKHKTSGK--VRLLMRREQVLKICANHYITADMALKPNAGSDK-SWVWYAMDYAD--EMPKTEQLAIRFKTADDAALFKVKFEEAQK 1268          
BLAST of RAN binding protein 2 vs. Ensembl Zebrafish
Match: ftr52p (finTRIM family, member 52, pseudogene [Source:ZFIN;Acc:ZDB-GENEP-110922-3])

HSP 1 Score: 93.9745 bits (232), Expect = 1.881e-21
Identity = 65/179 (36.31%), Postives = 88/179 (49.16%), Query Frame = 1
Query:  238 IFGLGNMKPDTKSSNFLFPIIP-QLPTLTNDDEG-----ENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQ 756
            IF L NM         +F   P Q     ND E      E P+N   ++ PI  L E+    GEE+ E LF ER +LY W ++WK+RG G +KI       KK Y ++MR EQ  KV  NH+I +     + M  +  S  W A D+SEG    K+  A+KF+T + +  FK    D Q
Sbjct:  323 IFTLSNM------GTSVFAGAPSQTEKAHNDGEKKKSDDEAPDNNEVEFDPIDPLTEMHP--GEEDEEILFKERTRLYHWDDQWKDRGFGNIKIFFHPL--KKRYHVLMRHEQSLKVCANHSISRG-SQLTPMNTSANSLTWTAIDYSEGDGKTKQ-LAVKFRTADQMKSFKRVFMDCQ 489          
BLAST of RAN binding protein 2 vs. Ensembl Zebrafish
Match: ranbp1 (RAN binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2548])

HSP 1 Score: 80.4925 bits (197), Expect = 6.179e-18
Identity = 50/134 (37.31%), Postives = 75/134 (55.97%), Query Frame = 1
Query:  349 NFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSN-----EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            N +P ++PI+SLPE +  T EE+ E LF  R KLY++++     EWKERG G++K+L  K   K S RL+MRR++  K+  NH I+       + G+++        DF++      E  AI+F   E   KFK
Sbjct:   22 NHDPHFEPIVSLPEQDVKTLEEDEEELFKMRAKLYRFASENDPPEWKERGTGDVKLLRHK--EKGSIRLLMRRDRTLKICANHHIMPLMELKPNAGSDRAWVWNTHADFADEKPKA-EMLAIRFLNAENAQKFK 152          
BLAST of RAN binding protein 2 vs. Ensembl Xenopus
Match: mcoln2 (mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908])

HSP 1 Score: 117.472 bits (293), Expect = 3.231e-29
Identity = 65/153 (42.48%), Postives = 96/153 (62.75%), Query Frame = 1
Query:  325 DDEGENPENFNPD---YQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            D++G + E  + D   ++PI+SLPEVE  +GEE+ E LF ER KLY+W    N+WKERG+G++KIL  K   K  YR++MRR+QV KV  NH I       S +  +  S  W A D+S+G   V E+ A++FKT+EL + F+   ++ Q+ +
Sbjct: 2615 DEDGSDDEVVHSDDVHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRAVNQWKERGVGDIKILFHK--EKGYYRVLMRRDQVLKVCANHVISTEI-KISPLNTSTNSLVWTATDYSDGEGKV-EQLAVRFKTKELTDSFQSKFEECQQNL 2763          

HSP 2 Score: 105.145 bits (261), Expect = 5.659e-25
Identity = 58/136 (42.65%), Postives = 88/136 (64.71%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            ++P++ LP+ +E  +GEEN + LF  R KLY++   SN+WKERG+G++KIL  + DN KS R+VMRR+QV K+  NH I  +  N   M   + +  W A DF+EG E   E FA++FK +E  + FK+  ++ +E
Sbjct: 2065 FEPVVPLPDLIEVTSGEENEQALFCHRAKLYRFDKDSNQWKERGIGDLKIL-QRLDN-KSARVVMRRDQVLKLCANHRITTDI-NLQPMKGAERAWVWTAHDFAEG-EGKTECFAVRFKLQEAADLFKEGFEEAKE 2196          

HSP 3 Score: 98.5969 bits (244), Expect = 9.817e-23
Identity = 60/153 (39.22%), Postives = 86/153 (56.21%), Query Frame = 1
Query:  319 TNDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
              DD  +  E  +  ++PI+ LP+ V+ +TGEE+ + L+S+R KLY++   S +WKERG+G +KIL  K D     R++MRREQV KV  NH I     N   +  +  S  W A DFS+G   + E+ A KFKT E    FK    + Q  +
Sbjct: 1761 ATDDLYKTEERDDIHFEPIVQLPDKVDLVTGEEDEKTLYSQRVKLYRFDATSGQWKERGVGNLKIL--KNDVNGKLRMLMRREQVLKVCANHWITTTM-NLKPLTGSDRSWMWMANDFSDGDARL-EQLAAKFKTPEQAEDFKTKFDECQRLL 1909          

HSP 4 Score: 85.8853 bits (211), Expect = 1.956e-18
Identity = 58/152 (38.16%), Postives = 88/152 (57.89%), Query Frame = 1
Query:  325 DDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQEKM 765
            DD+G       P ++PI+ LPE +E  TGEE+ E +F  R KL+++   + EWKERG+G +KIL  +   K   RL+MRREQV K+  NH I  +     +  ++K S  W A D+++  E+ K E+ AI+FKT +    FK   ++ Q  +
Sbjct: 1113 DDDG-------PHFEPIVPLPEKIEVRTGEEDEEEMFCNRAKLFRFDAETKEWKERGIGNVKILRHRVSGK--IRLLMRREQVLKICANHYINADMKLKPNATSDK-SYVWNAYDYAD--EMPKPEQLAIRFKTVDEAVLFKTKFEEAQRLL 1252          
BLAST of RAN binding protein 2 vs. Ensembl Xenopus
Match: mcoln2 (mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908])

HSP 1 Score: 117.472 bits (293), Expect = 3.237e-29
Identity = 65/153 (42.48%), Postives = 96/153 (62.75%), Query Frame = 1
Query:  325 DDEGENPENFNPD---YQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            D++G + E  + D   ++PI+SLPEVE  +GEE+ E LF ER KLY+W    N+WKERG+G++KIL  K   K  YR++MRR+QV KV  NH I       S +  +  S  W A D+S+G   V E+ A++FKT+EL + F+   ++ Q+ +
Sbjct: 2690 DEDGSDDEVVHSDDVHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRAVNQWKERGVGDIKILFHK--EKGYYRVLMRRDQVLKVCANHVISTEI-KISPLNTSTNSLVWTATDYSDGEGKV-EQLAVRFKTKELTDSFQSKFEECQQNL 2838          

HSP 2 Score: 105.145 bits (261), Expect = 5.563e-25
Identity = 58/136 (42.65%), Postives = 88/136 (64.71%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            ++P++ LP+ +E  +GEEN + LF  R KLY++   SN+WKERG+G++KIL  + DN KS R+VMRR+QV K+  NH I  +  N   M   + +  W A DF+EG E   E FA++FK +E  + FK+  ++ +E
Sbjct: 2117 FEPVVPLPDLIEVTSGEENEQALFCHRAKLYRFDKDSNQWKERGIGDLKIL-QRLDN-KSARVVMRRDQVLKLCANHRITTDI-NLQPMKGAERAWVWTAHDFAEG-EGKTECFAVRFKLQEAADLFKEGFEEAKE 2248          

HSP 3 Score: 98.5969 bits (244), Expect = 1.082e-22
Identity = 60/153 (39.22%), Postives = 86/153 (56.21%), Query Frame = 1
Query:  319 TNDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
              DD  +  E  +  ++PI+ LP+ V+ +TGEE+ + L+S+R KLY++   S +WKERG+G +KIL  K D     R++MRREQV KV  NH I     N   +  +  S  W A DFS+G   + E+ A KFKT E    FK    + Q  +
Sbjct: 1813 ATDDLYKTEERDDIHFEPIVQLPDKVDLVTGEEDEKTLYSQRVKLYRFDATSGQWKERGVGNLKIL--KNDVNGKLRMLMRREQVLKVCANHWITTTM-NLKPLTGSDRSWMWMANDFSDGDARL-EQLAAKFKTPEQAEDFKTKFDECQRLL 1961          

HSP 4 Score: 85.8853 bits (211), Expect = 2.016e-18
Identity = 58/152 (38.16%), Postives = 88/152 (57.89%), Query Frame = 1
Query:  325 DDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQEKM 765
            DD+G       P ++PI+ LPE +E  TGEE+ E +F  R KL+++   + EWKERG+G +KIL  +   K   RL+MRREQV K+  NH I  +     +  ++K S  W A D+++  E+ K E+ AI+FKT +    FK   ++ Q  +
Sbjct: 1165 DDDG-------PHFEPIVPLPEKIEVRTGEEDEEEMFCNRAKLFRFDAETKEWKERGIGNVKILRHRVSGK--IRLLMRREQVLKICANHYINADMKLKPNATSDK-SYVWNAYDYAD--EMPKPEQLAIRFKTVDEAVLFKTKFEEAQRLL 1304          
BLAST of RAN binding protein 2 vs. Ensembl Xenopus
Match: mcoln2 (mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908])

HSP 1 Score: 117.472 bits (293), Expect = 3.323e-29
Identity = 65/153 (42.48%), Postives = 96/153 (62.75%), Query Frame = 1
Query:  325 DDEGENPENFNPD---YQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            D++G + E  + D   ++PI+SLPEVE  +GEE+ E LF ER KLY+W    N+WKERG+G++KIL  K   K  YR++MRR+QV KV  NH I       S +  +  S  W A D+S+G   V E+ A++FKT+EL + F+   ++ Q+ +
Sbjct: 2588 DEDGSDDEVVHSDDVHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRAVNQWKERGVGDIKILFHK--EKGYYRVLMRRDQVLKVCANHVISTEI-KISPLNTSTNSLVWTATDYSDGEGKV-EQLAVRFKTKELTDSFQSKFEECQQNL 2736          

HSP 2 Score: 105.145 bits (261), Expect = 5.655e-25
Identity = 58/136 (42.65%), Postives = 88/136 (64.71%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            ++P++ LP+ +E  +GEEN + LF  R KLY++   SN+WKERG+G++KIL  + DN KS R+VMRR+QV K+  NH I  +  N   M   + +  W A DF+EG E   E FA++FK +E  + FK+  ++ +E
Sbjct: 2066 FEPVVPLPDLIEVTSGEENEQALFCHRAKLYRFDKDSNQWKERGIGDLKIL-QRLDN-KSARVVMRRDQVLKLCANHRITTDI-NLQPMKGAERAWVWTAHDFAEG-EGKTECFAVRFKLQEAADLFKEGFEEAKE 2197          

HSP 3 Score: 98.5969 bits (244), Expect = 1.058e-22
Identity = 60/153 (39.22%), Postives = 86/153 (56.21%), Query Frame = 1
Query:  319 TNDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
              DD  +  E  +  ++PI+ LP+ V+ +TGEE+ + L+S+R KLY++   S +WKERG+G +KIL  K D     R++MRREQV KV  NH I     N   +  +  S  W A DFS+G   + E+ A KFKT E    FK    + Q  +
Sbjct: 1762 ATDDLYKTEERDDIHFEPIVQLPDKVDLVTGEEDEKTLYSQRVKLYRFDATSGQWKERGVGNLKIL--KNDVNGKLRMLMRREQVLKVCANHWITTTM-NLKPLTGSDRSWMWMANDFSDGDARL-EQLAAKFKTPEQAEDFKTKFDECQRLL 1910          

HSP 4 Score: 85.8853 bits (211), Expect = 1.973e-18
Identity = 58/152 (38.16%), Postives = 88/152 (57.89%), Query Frame = 1
Query:  325 DDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQEKM 765
            DD+G       P ++PI+ LPE +E  TGEE+ E +F  R KL+++   + EWKERG+G +KIL  +   K   RL+MRREQV K+  NH I  +     +  ++K S  W A D+++  E+ K E+ AI+FKT +    FK   ++ Q  +
Sbjct: 1139 DDDG-------PHFEPIVPLPEKIEVRTGEEDEEEMFCNRAKLFRFDAETKEWKERGIGNVKILRHRVSGK--IRLLMRREQVLKICANHYINADMKLKPNATSDK-SYVWNAYDYAD--EMPKPEQLAIRFKTVDEAVLFKTKFEEAQRLL 1278          
BLAST of RAN binding protein 2 vs. Ensembl Xenopus
Match: mcoln2 (mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908])

HSP 1 Score: 117.472 bits (293), Expect = 3.484e-29
Identity = 65/153 (42.48%), Postives = 96/153 (62.75%), Query Frame = 1
Query:  325 DDEGENPENFNPD---YQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            D++G + E  + D   ++PI+SLPEVE  +GEE+ E LF ER KLY+W    N+WKERG+G++KIL  K   K  YR++MRR+QV KV  NH I       S +  +  S  W A D+S+G   V E+ A++FKT+EL + F+   ++ Q+ +
Sbjct: 2572 DEDGSDDEVVHSDDVHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRAVNQWKERGVGDIKILFHK--EKGYYRVLMRRDQVLKVCANHVISTEI-KISPLNTSTNSLVWTATDYSDGEGKV-EQLAVRFKTKELTDSFQSKFEECQQNL 2720          

HSP 2 Score: 105.145 bits (261), Expect = 5.761e-25
Identity = 58/136 (42.65%), Postives = 88/136 (64.71%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            ++P++ LP+ +E  +GEEN + LF  R KLY++   SN+WKERG+G++KIL  + DN KS R+VMRR+QV K+  NH I  +  N   M   + +  W A DF+EG E   E FA++FK +E  + FK+  ++ +E
Sbjct: 2065 FEPVVPLPDLIEVTSGEENEQALFCHRAKLYRFDKDSNQWKERGIGDLKIL-QRLDN-KSARVVMRRDQVLKLCANHRITTDI-NLQPMKGAERAWVWTAHDFAEG-EGKTECFAVRFKLQEAADLFKEGFEEAKE 2196          

HSP 3 Score: 98.5969 bits (244), Expect = 1.120e-22
Identity = 60/153 (39.22%), Postives = 86/153 (56.21%), Query Frame = 1
Query:  319 TNDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
              DD  +  E  +  ++PI+ LP+ V+ +TGEE+ + L+S+R KLY++   S +WKERG+G +KIL  K D     R++MRREQV KV  NH I     N   +  +  S  W A DFS+G   + E+ A KFKT E    FK    + Q  +
Sbjct: 1761 ATDDLYKTEERDDIHFEPIVQLPDKVDLVTGEEDEKTLYSQRVKLYRFDATSGQWKERGVGNLKIL--KNDVNGKLRMLMRREQVLKVCANHWITTTM-NLKPLTGSDRSWMWMANDFSDGDARL-EQLAAKFKTPEQAEDFKTKFDECQRLL 1909          

HSP 4 Score: 85.8853 bits (211), Expect = 2.048e-18
Identity = 58/152 (38.16%), Postives = 88/152 (57.89%), Query Frame = 1
Query:  325 DDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQEKM 765
            DD+G       P ++PI+ LPE +E  TGEE+ E +F  R KL+++   + EWKERG+G +KIL  +   K   RL+MRREQV K+  NH I  +     +  ++K S  W A D+++  E+ K E+ AI+FKT +    FK   ++ Q  +
Sbjct: 1139 DDDG-------PHFEPIVPLPEKIEVRTGEEDEEEMFCNRAKLFRFDAETKEWKERGIGNVKILRHRVSGK--IRLLMRREQVLKICANHYINADMKLKPNATSDK-SYVWNAYDYAD--EMPKPEQLAIRFKTVDEAVLFKTKFEEAQRLL 1278          
BLAST of RAN binding protein 2 vs. Ensembl Xenopus
Match: mcoln2 (mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908])

HSP 1 Score: 117.087 bits (292), Expect = 3.955e-29
Identity = 65/153 (42.48%), Postives = 96/153 (62.75%), Query Frame = 1
Query:  325 DDEGENPENFNPD---YQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            D++G + E  + D   ++PI+SLPEVE  +GEE+ E LF ER KLY+W    N+WKERG+G++KIL  K   K  YR++MRR+QV KV  NH I       S +  +  S  W A D+S+G   V E+ A++FKT+EL + F+   ++ Q+ +
Sbjct: 2667 DEDGSDDEVVHSDDVHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRAVNQWKERGVGDIKILFHK--EKGYYRVLMRRDQVLKVCANHVISTEI-KISPLNTSTNSLVWTATDYSDGEGKV-EQLAVRFKTKELTDSFQSKFEECQQNL 2815          

HSP 2 Score: 104.76 bits (260), Expect = 7.328e-25
Identity = 58/136 (42.65%), Postives = 88/136 (64.71%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            ++P++ LP+ +E  +GEEN + LF  R KLY++   SN+WKERG+G++KIL  + DN KS R+VMRR+QV K+  NH I  +  N   M   + +  W A DF+EG E   E FA++FK +E  + FK+  ++ +E
Sbjct: 2125 FEPVVPLPDLIEVTSGEENEQALFCHRAKLYRFDKDSNQWKERGIGDLKIL-QRLDN-KSARVVMRRDQVLKLCANHRITTDI-NLQPMKGAERAWVWTAHDFAEG-EGKTECFAVRFKLQEAADLFKEGFEEAKE 2256          

HSP 3 Score: 98.2117 bits (243), Expect = 1.307e-22
Identity = 60/153 (39.22%), Postives = 86/153 (56.21%), Query Frame = 1
Query:  319 TNDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
              DD  +  E  +  ++PI+ LP+ V+ +TGEE+ + L+S+R KLY++   S +WKERG+G +KIL  K D     R++MRREQV KV  NH I     N   +  +  S  W A DFS+G   + E+ A KFKT E    FK    + Q  +
Sbjct: 1821 ATDDLYKTEERDDIHFEPIVQLPDKVDLVTGEEDEKTLYSQRVKLYRFDATSGQWKERGVGNLKIL--KNDVNGKLRMLMRREQVLKVCANHWITTTM-NLKPLTGSDRSWMWMANDFSDGDARL-EQLAAKFKTPEQAEDFKTKFDECQRLL 1969          

HSP 4 Score: 85.8853 bits (211), Expect = 2.388e-18
Identity = 58/152 (38.16%), Postives = 88/152 (57.89%), Query Frame = 1
Query:  325 DDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQEKM 765
            DD+G       P ++PI+ LPE +E  TGEE+ E +F  R KL+++   + EWKERG+G +KIL  +   K   RL+MRREQV K+  NH I  +     +  ++K S  W A D+++  E+ K E+ AI+FKT +    FK   ++ Q  +
Sbjct: 1173 DDDG-------PHFEPIVPLPEKIEVRTGEEDEEEMFCNRAKLFRFDAETKEWKERGIGNVKILRHRVSGK--IRLLMRREQVLKICANHYINADMKLKPNATSDK-SYVWNAYDYAD--EMPKPEQLAIRFKTVDEAVLFKTKFEEAQRLL 1312          
BLAST of RAN binding protein 2 vs. Ensembl Mouse
Match: Ranbp2 (RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323])

HSP 1 Score: 112.464 bits (280), Expect = 1.348e-27
Identity = 57/137 (41.61%), Postives = 87/137 (63.50%), Query Frame = 1
Query:  364 YQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++PI+SLPEVE  +GEE+ E LF ER KLY+W    ++WKERG+G++KIL      KK YR++MRR+QV KV  NH I +       +  +  +  W A D+++G   V E+ A++FKT+E+   FK   ++ Q+ +
Sbjct: 2741 FEPIVSLPEVEVKSGEEDEEVLFKERAKLYRWDRDVSQWKERGIGDIKILWHTM--KKYYRILMRRDQVFKVCANHVITKAM-ELKPLNVSNNALVWTASDYADGEAKV-EQLAVRFKTKEMTESFKKKFEECQQNI 2873          

HSP 2 Score: 102.449 bits (254), Expect = 3.927e-24
Identity = 58/152 (38.16%), Postives = 92/152 (60.53%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +DD  +  ++ +  ++P++ +PE VE +TGEE+ + L+S+R KL+++  E   WKERGLG +KIL ++ + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q  +
Sbjct: 1836 DDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRVKLFRFDAEISQWKERGLGNLKILKNEVNGK--LRMLMRREQVLKVCANHWITTTM-NLKPLSGSDRAWMWLASDFSDGDAKL-EQLAAKFKTPELAEEFKQKFEECQRLL 1983          

HSP 3 Score: 93.5893 bits (231), Expect = 4.068e-21
Identity = 55/140 (39.29%), Postives = 85/140 (60.71%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R KLY++     +WKERG+G++KIL +  DNK+  R+VMRR+QV K+  NH I  +      M   +    W A DF++G   + E  A++FK +++ + FK   D  K  QEK
Sbjct: 2147 FEPVVPLPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDIKILQN-YDNKQ-VRIVMRRDQVLKLCANHRITPDM-TLQTMKGTERVWVWTACDFADGERKI-EHLAVRFKLQDVADSFKKIFDEAKTAQEK 2282          

HSP 4 Score: 93.5893 bits (231), Expect = 4.306e-21
Identity = 59/142 (41.55%), Postives = 86/142 (60.56%), Query Frame = 1
Query:  346 ENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQ 756
            E+  P ++P++ LP+ +E  TGEE+ E  F  R KL+++   S EWKERG+G +KIL  KT  K   RL+MRREQV K+  NH I  +     + G+++ S  W A D+++  EL K E+ AI+FKT E    FK   ++ Q
Sbjct: 1160 EDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDGESKEWKERGIGNVKILRHKTSGK--IRLLMRREQVLKICANHYISPDMKLTPNAGSDR-SFVWHALDYAD--ELPKPEQLAIRFKTPEEAALFKCKFEEAQ 1296          
BLAST of RAN binding protein 2 vs. Ensembl Mouse
Match: Ranbp1 (RAN binding protein 1 [Source:MGI Symbol;Acc:MGI:96269])

HSP 1 Score: 77.7962 bits (190), Expect = 6.167e-17
Identity = 53/151 (35.10%), Postives = 85/151 (56.29%), Query Frame = 1
Query:  349 NFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSN-----EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSE---GTELVKEKF-----AIKFKTEELLNKFKDTIKDLQEK 762
            N +P ++PI+SLPE E  T EE+ E LF  R KL+++++     EWKERG G++K+L  K   K + RL+MRR++  K+  NH I        + G+++        DF++     EL+  +F     A KFKT     KF++  K+++E+
Sbjct:   22 NHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHK--EKGTIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKT-----KFEECRKEIEER 165          
BLAST of RAN binding protein 2 vs. Ensembl Mouse
Match: Ranbp1 (RAN binding protein 1 [Source:MGI Symbol;Acc:MGI:96269])

HSP 1 Score: 77.7962 bits (190), Expect = 6.167e-17
Identity = 53/151 (35.10%), Postives = 85/151 (56.29%), Query Frame = 1
Query:  349 NFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSN-----EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSE---GTELVKEKF-----AIKFKTEELLNKFKDTIKDLQEK 762
            N +P ++PI+SLPE E  T EE+ E LF  R KL+++++     EWKERG G++K+L  K   K + RL+MRR++  K+  NH I        + G+++        DF++     EL+  +F     A KFKT     KF++  K+++E+
Sbjct:   22 NHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHK--EKGTIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKT-----KFEECRKEIEER 165          
BLAST of RAN binding protein 2 vs. Ensembl Mouse
Match: Ranbp1 (RAN binding protein 1 [Source:MGI Symbol;Acc:MGI:96269])

HSP 1 Score: 47.3654 bits (111), Expect = 2.529e-6
Identity = 38/121 (31.40%), Postives = 65/121 (53.72%), Query Frame = 1
Query:  439 RCKLYKWSNE-----WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSE---GTELVKEKF-----AIKFKTEELLNKFKDTIKDLQEK 762
            R KL+++++E     WKERG G++K+L  K   K + RL+MRR++  K+  NH I        + G+++        DF++     EL+  +F     A KFKT     KF++  K+++E+
Sbjct:    2 RAKLFRFASENDLPEWKERGTGDVKLLKHK--EKGTIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKT-----KFEECRKEIEER 115          
BLAST of RAN binding protein 2 vs. Ensembl Mouse
Match: Ranbp1 (RAN binding protein 1 [Source:MGI Symbol;Acc:MGI:96269])

HSP 1 Score: 47.3654 bits (111), Expect = 2.529e-6
Identity = 38/121 (31.40%), Postives = 65/121 (53.72%), Query Frame = 1
Query:  439 RCKLYKWSNE-----WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSE---GTELVKEKF-----AIKFKTEELLNKFKDTIKDLQEK 762
            R KL+++++E     WKERG G++K+L  K   K + RL+MRR++  K+  NH I        + G+++        DF++     EL+  +F     A KFKT     KF++  K+++E+
Sbjct:    2 RAKLFRFASENDLPEWKERGTGDVKLLKHK--EKGTIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKT-----KFEECRKEIEER 115          
BLAST of RAN binding protein 2 vs. UniProt/SwissProt
Match: sp|Q9ERU9|RBP2_MOUSE (E3 SUMO-protein ligase RanBP2 OS=Mus musculus OX=10090 GN=Ranbp2 PE=1 SV=2)

HSP 1 Score: 112.464 bits (280), Expect = 9.428e-27
Identity = 57/137 (41.61%), Postives = 87/137 (63.50%), Query Frame = 1
Query:  364 YQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++PI+SLPEVE  +GEE+ E LF ER KLY+W    ++WKERG+G++KIL      KK YR++MRR+QV KV  NH I +       +  +  +  W A D+++G   V E+ A++FKT+E+   FK   ++ Q+ +
Sbjct: 2741 FEPIVSLPEVEVKSGEEDEEVLFKERAKLYRWDRDVSQWKERGIGDIKILWHTM--KKYYRILMRRDQVFKVCANHVITKAM-ELKPLNVSNNALVWTASDYADGEAKV-EQLAVRFKTKEMTESFKKKFEECQQNI 2873          

HSP 2 Score: 102.449 bits (254), Expect = 2.747e-23
Identity = 58/152 (38.16%), Postives = 92/152 (60.53%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +DD  +  ++ +  ++P++ +PE VE +TGEE+ + L+S+R KL+++  E   WKERGLG +KIL ++ + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q  +
Sbjct: 1836 DDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRVKLFRFDAEISQWKERGLGNLKILKNEVNGK--LRMLMRREQVLKVCANHWITTTM-NLKPLSGSDRAWMWLASDFSDGDAKL-EQLAAKFKTPELAEEFKQKFEECQRLL 1983          

HSP 3 Score: 93.5893 bits (231), Expect = 2.846e-20
Identity = 55/140 (39.29%), Postives = 85/140 (60.71%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R KLY++     +WKERG+G++KIL +  DNK+  R+VMRR+QV K+  NH I  +      M   +    W A DF++G   + E  A++FK +++ + FK   D  K  QEK
Sbjct: 2147 FEPVVPLPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDIKILQN-YDNKQ-VRIVMRRDQVLKLCANHRITPDM-TLQTMKGTERVWVWTACDFADGERKI-EHLAVRFKLQDVADSFKKIFDEAKTAQEK 2282          

HSP 4 Score: 93.5893 bits (231), Expect = 3.012e-20
Identity = 59/142 (41.55%), Postives = 86/142 (60.56%), Query Frame = 1
Query:  346 ENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQ 756
            E+  P ++P++ LP+ +E  TGEE+ E  F  R KL+++   S EWKERG+G +KIL  KT  K   RL+MRREQV K+  NH I  +     + G+++ S  W A D+++  EL K E+ AI+FKT E    FK   ++ Q
Sbjct: 1160 EDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDGESKEWKERGIGNVKILRHKTSGK--IRLLMRREQVLKICANHYISPDMKLTPNAGSDR-SFVWHALDYAD--ELPKPEQLAIRFKTPEEAALFKCKFEEAQ 1296          
BLAST of RAN binding protein 2 vs. UniProt/SwissProt
Match: sp|H2QII6|RBP2_PANTR (E3 SUMO-protein ligase RanBP2 OS=Pan troglodytes OX=9598 GN=RANBP2 PE=1 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 9.643e-27
Identity = 61/153 (39.87%), Postives = 96/153 (62.75%), Query Frame = 1
Query:  325 DDEGENPE---NFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            D++G + E   N +  ++PI+SLPEVE  +GEE+ E LF ER KLY+W    ++WKERG+G++KIL     N   YR++MRR+QV KV  NH I +       +  +  +  W A D+++G   V E+ A++FKT+E+ + FK T ++ Q+ +
Sbjct: 2896 DEDGSDEEVVHNEDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDVSQWKERGVGDIKILWHTMKN--YYRILMRRDQVFKVCANHVITKTM-ELKPLNVSNNALVWTASDYADGEAKV-EQLAVRFKTKEVADCFKKTFEECQQNL 3044          

HSP 2 Score: 102.064 bits (253), Expect = 3.667e-23
Identity = 58/152 (38.16%), Postives = 92/152 (60.53%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +DD  +  ++ +  ++P++ +PE VE +TGEE+ + L+S+R KL+++  E   WKERGLG +KIL ++ + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q  +
Sbjct: 1999 DDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRVKLFRFDAEVSQWKERGLGNLKILKNEVNGK--LRMLMRREQVLKVCANHWITTTM-NLKPLSGSDRAWMWLASDFSDGDAKL-EQLAAKFKTPELAEEFKQKFEECQRLL 2146          

HSP 3 Score: 94.7449 bits (234), Expect = 1.239e-20
Identity = 56/140 (40.00%), Postives = 86/140 (61.43%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R KLY++     +WKERG+G++KIL +  DNK+  R+VMRR+QV K+  NH I  +     +M   +    W A DF++G   V E  A++FK +++ + FK   D  K  QEK
Sbjct: 2310 FEPVVPLPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDIKILQN-YDNKQ-VRIVMRRDQVLKLCANHRITPDM-TLQNMKGTERVWLWTAYDFADGERKV-EHLAVRFKLQDVADSFKKIFDEAKTAQEK 2445          

HSP 4 Score: 92.8189 bits (229), Expect = 5.138e-20
Identity = 58/138 (42.03%), Postives = 84/138 (60.87%), Query Frame = 1
Query:  358 PDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQ 756
            P ++P++ LP+ +E  TGEE+ E  F  R KL+++   S EWKERG+G +KIL  KT  K   RL+MRREQV K+  NH I  +     + G+++ S  W A D+++  EL K E+ AI+FKT E    FK   ++ Q
Sbjct: 1170 PHFEPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDVESKEWKERGIGNVKILRHKTSGK--IRLLMRREQVLKICANHYISPDMKLTPNAGSDR-SFVWHALDYAD--ELPKPEQLAIRFKTPEEAALFKCKFEEAQ 1302          
BLAST of RAN binding protein 2 vs. UniProt/SwissProt
Match: sp|P49792|RBP2_HUMAN (E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2)

HSP 1 Score: 112.464 bits (280), Expect = 1.051e-26
Identity = 61/153 (39.87%), Postives = 96/153 (62.75%), Query Frame = 1
Query:  325 DDEGENPE---NFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            D++G + E   N +  ++PI+SLPEVE  +GEE+ E LF ER KLY+W    ++WKERG+G++KIL     N   YR++MRR+QV KV  NH I +       +  +  +  W A D+++G   V E+ A++FKT+E+ + FK T ++ Q+ +
Sbjct: 2896 DEDGSDEEVVHNEDIHFEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDRDVSQWKERGVGDIKILWHTMKN--YYRILMRRDQVFKVCANHVITKTM-ELKPLNVSNNALVWTASDYADGEAKV-EQLAVRFKTKEVADCFKKTFEECQQNL 3044          

HSP 2 Score: 102.064 bits (253), Expect = 4.033e-23
Identity = 58/152 (38.16%), Postives = 92/152 (60.53%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            +DD  +  ++ +  ++P++ +PE VE +TGEE+ + L+S+R KL+++  E   WKERGLG +KIL ++ + K   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A KFKT EL  +FK   ++ Q  +
Sbjct: 1999 DDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRVKLFRFDAEVSQWKERGLGNLKILKNEVNGK--LRMLMRREQVLKVCANHWITTTM-NLKPLSGSDRAWMWLASDFSDGDAKL-EQLAAKFKTPELAEEFKQKFEECQRLL 2146          

HSP 3 Score: 93.9745 bits (232), Expect = 1.917e-20
Identity = 56/140 (40.00%), Postives = 86/140 (61.43%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R KLY++     +WKERG+G++KIL +  DNK+  R+VMRR+QV K+  NH I  +     +M   +    W A DF++G   V E  A++FK +++ + FK   D  K  QEK
Sbjct: 2310 FEPVVPLPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDIKILQN-YDNKQ-VRIVMRRDQVLKLCANHRITPDM-TLQNMKGTERVWLWTACDFADGERKV-EHLAVRFKLQDVADSFKKIFDEAKTAQEK 2445          

HSP 4 Score: 92.8189 bits (229), Expect = 5.237e-20
Identity = 58/138 (42.03%), Postives = 84/138 (60.87%), Query Frame = 1
Query:  358 PDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQ 756
            P ++P++ LP+ +E  TGEE+ E  F  R KL+++   S EWKERG+G +KIL  KT  K   RL+MRREQV K+  NH I  +     + G+++ S  W A D+++  EL K E+ AI+FKT E    FK   ++ Q
Sbjct: 1170 PHFEPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDVESKEWKERGIGNVKILRHKTSGK--IRLLMRREQVLKICANHYISPDMKLTPNAGSDR-SFVWHALDYAD--ELPKPEQLAIRFKTPEEAALFKCKFEEAQ 1302          
BLAST of RAN binding protein 2 vs. UniProt/SwissProt
Match: sp|A0A0B4K7J2|RBP2_DROME (E3 SUMO-protein ligase RanBP2 OS=Drosophila melanogaster OX=7227 GN=Nup358 PE=1 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 3.914e-26
Identity = 59/146 (40.41%), Postives = 90/146 (61.64%), Query Frame = 1
Query:  346 ENFNPDYQ--PIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            E + P  Q  P+I+LP+ VE +TGEEN + LF  R KL +W   +NEWKERGLG MK+L  +TD  K  RL+MRREQV K+ CN  ++     F+     K +  W A+D+S+  EL     A++FK++++  +F + ++  Q+ +
Sbjct: 1598 EEYVPTAQFVPVIALPDIVEVVTGEENEDVLFEHRAKLLRWDKEANEWKERGLGNMKLLRDRTDPNK-VRLLMRREQVHKLCCNQRLLPET-KFTYATNCKAAVTWGAQDYSD-EELTTALLAVRFKSQDICQQFLEAVQKAQQSI 1740          

HSP 2 Score: 98.2117 bits (243), Expect = 6.713e-22
Identity = 54/129 (41.86%), Postives = 79/129 (61.24%), Query Frame = 1
Query:  358 PDYQPIISLP-EVETITGEENSECLFSERCKLYKWSN-EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCP-NFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            PD++PII LP EVE  TGEE  +  F+ R KL+++ + EWKERG G +KIL  K       R++MRR+Q  KV  NH I  +   N ++   +K S  W A DF++  ++  E+F ++FKT EL  +F+
Sbjct: 1308 PDFKPIIPLPDEVEVRTGEEGEDIKFTSRAKLFRYVDKEWKERGTGVIKILCDKATGVS--RVLMRRDQTHKVCANHTITADITINVANQDKDKKSLLWAANDFAD-EQVTLERFLVRFKTGELAEEFR 1433          

HSP 3 Score: 94.3597 bits (233), Expect = 1.322e-20
Identity = 58/147 (39.46%), Postives = 86/147 (58.50%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWS-NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWF--AEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKD 750
            ND +    E  N  + P+I LP+ ++  TGEE+ E L+  + KLY+ + ++WKERGLG++KIL  +    K  R+VMRREQV K+  NH + +N      +   KT   W     DFSEG E V E+F ++FK +E+   F + IK+
Sbjct: 2006 NDSQEVEEEENNTYFSPVIPLPDKIDVKTGEEDEELLYVHKAKLYRLNESDWKERGLGDVKILRHR--QTKKLRVVMRREQVFKICLNHVLNENV-----VYREKTETSWMFAVHDFSEG-ESVLERFTLRFKNKEVAQGFMEAIKN 2144          

HSP 4 Score: 92.8189 bits (229), Expect = 5.379e-20
Identity = 55/142 (38.73%), Postives = 84/142 (59.15%), Query Frame = 1
Query:  349 NFNPDYQPIISLP-EVETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDF---SEG---TELVKEKFAIKFKTEELLNKFKDTI 744
            N++P Y  I+ LP E+   TGEEN   LF ER KLY++   S +WKERG+GE+K+L  +    +++RL+MR+EQ+ K+V N  I  +      M A   S  W   ++   +EG   TE V E+ A +F  EE+ ++F +T+
Sbjct: 2552 NYDPHYDAIVELPDEIVVTTGEENETKLFGERAKLYRYDAESKQWKERGVGEIKVL--EHPELQTFRLIMRQEQIHKLVLNMNISASL-QMDYMNAQMKSFLWAGYNYAVDAEGKVDTEGVLERLACRFAKEEIASEFLNTV 2690          
BLAST of RAN binding protein 2 vs. UniProt/SwissProt
Match: sp|P48820|RBP2_BOVIN (E3 SUMO-protein ligase RanBP2 (Fragment) OS=Bos taurus OX=9913 GN=RANBP2 PE=2 SV=2)

HSP 1 Score: 109.768 bits (273), Expect = 8.070e-26
Identity = 54/137 (39.42%), Postives = 88/137 (64.23%), Query Frame = 1
Query:  364 YQPIISLPEVETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++PI+SLPEVE  +GEE+ E LF ER KLY+W   +++WK+RG+G++KIL     N   +R++MRR+QV KV  NH I +       +  +  +  W A D+++G   V E+ A++FKT+E+ + FK   ++ Q+ +
Sbjct:  773 FEPIVSLPEVEVKSGEEDEEILFKERAKLYRWDREASQWKDRGVGDIKILWHTVKN--YFRILMRRDQVFKVCANHVITKTM-ELKPLNVSNNALVWTASDYADGEAKV-EQLAVRFKTKEMADCFKKKFEECQQNL 905          

HSP 2 Score: 93.5893 bits (231), Expect = 2.336e-20
Identity = 53/140 (37.86%), Postives = 85/140 (60.71%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK---DTIKDLQEK 762
            ++P++ LP+ VE  +GEEN + +FS R KLY++   + +WKERG+G++KIL +  +  K  R+VMRR+QV K+  NH I  +     +M   +    W A DF++G   + E  A++FK +++ + FK   D  K  QEK
Sbjct:  175 FEPVVPLPDLVEVSSGEENEQVVFSHRAKLYRYDKDAGQWKERGIGDIKILQNYEN--KQVRIVMRRDQVLKLCANHRITPDM-TLQNMKGTERVWVWTACDFADGERKI-EHLAVRFKLQDVADSFKKIFDEAKVAQEK 310          
BLAST of RAN binding protein 2 vs. TrEMBL
Match: A0A0F7GYG2 (RAN binding protein 2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 2.403e-34
Identity = 71/144 (49.31%), Postives = 96/144 (66.67%), Query Frame = 1
Query:  346 ENFNPDYQPIISLPEVETITG-EENSECLFSERCKLYKW-SNEWKERGLGEMKILASK--TDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            E  +P +QPII LP + ++   EE  + LF  RCKLY++ +NEWKERG+GEMKIL +K   D  K  +LVMRR+QVRK+ CN  + +N P F++M  N  S CW   DFSEG E  +EKFAI+F   + LNKFK  ++ +Q +M
Sbjct:  269 EEHDPHFQPIIDLPPLVSVQKDEELHDVLFRSRCKLYRFINNEWKERGVGEMKILQTKESVDQSKPVKLVMRRDQVRKICCNQRVSKNVPAFTEM-PNVKSTCWVGNDFSEG-EPAQEKFAIRFAHVDELNKFKGIVEKIQSEM 410          
BLAST of RAN binding protein 2 vs. TrEMBL
Match: T1IZQ7 (Uncharacterized protein OS=Strigamia maritima OX=126957 PE=4 SV=1)

HSP 1 Score: 139.813 bits (351), Expect = 1.129e-33
Identity = 95/270 (35.19%), Postives = 144/270 (53.33%), Query Frame = 1
Query:   67 SDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHG-------------DNESSNEVEAVKQEPLIF----GL---------GNMKPDTKSSNFLFP----IIPQLPTLTNDDEGEN---PENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            + +D  IV E  A  ++ K+A  L LP NFY+YE      G             ++ES  E EA K   L+F    GL         G       S  F F     ++ + P   ++ +GE+   P   +  + PI+ LP+ +E  TGEE+ + +F++R KLY++     EWKERG+G+ KIL  K  N+  YR+++RREQ+ K+ CNH+I  +  N S +  ++T+ CW A DF+E    V E+FAIKFK+ EL  KF++  K+ QE +
Sbjct: 2310 TGNDFEIVKESKAEPDRVKQAMDLKLPPNFYLYEKKDPCPGCRGCDKCETNEKSNDESKTEAEAEKST-LLFKDSTGLDFANLAKKEGQTFTTQTSPGFAFGTGNVMVFKPPKANDNSDGEDESTPHQPDIHFDPIVPLPDLIEVKTGEEDEDIVFTQRAKLYRYDLDKKEWKERGVGDAKILKHKKTNR--YRMILRREQIYKIACNHSITPDM-NLSPLATSETAMCWSAMDFAESETGVPEQFAIKFKSIELTKKFEEKFKECQENL 2575          

HSP 2 Score: 108.997 bits (271), Expect = 4.146e-23
Identity = 63/147 (42.86%), Postives = 91/147 (61.90%), Query Frame = 1
Query:  328 DEGENPENFNPDYQPIISLP-EVETITGEENSECLFSERCKLYKWSN-EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEK 762
            DE +  E+   D+QP+I LP EVE  TGEE    LF  R KL+++ N EWKERG+G +KIL ++   +   R++MRR+QV K+  NH I+ N    + M  N+T+  W A DF++  ++V E+F +KFKT E+   FK   +  QEK
Sbjct: 1217 DEEQTEESTGGDFQPVIPLPDEVEVRTGEEEECVLFESRAKLFRFVNKEWKERGIGMLKILFNEKTGRS--RILMRRDQVWKICANHFILSNM-KLTSMKDNETTWVWAANDFAD-EKMVMERFCVKFKTAEIAQNFKTEFEKAQEK 1359          

HSP 3 Score: 102.834 bits (255), Expect = 6.338e-21
Identity = 56/138 (40.58%), Postives = 88/138 (63.77%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++PI+ LPE VE  TGEE+   LF ER +LY++   + +WKERG+GE+KIL ++T    ++R++MRREQV KV  NH I +     + +  +  +  W A+DFSE  E   E FA++FK++E+  KF    +D  +++
Sbjct: 1685 FEPIVPLPELVEVRTGEEDDNKLFGERARLYRFDSDTQQWKERGIGEIKILENRTTG--AFRILMRREQVHKVCANHRI-EAYMELTKLLTSDRALSWAAKDFSEEVE-SDETFAVRFKSQEMAEKFLQVFQDCLKRL 1818          

HSP 4 Score: 84.3445 bits (207), Expect = 1.222e-14
Identity = 52/133 (39.10%), Postives = 76/133 (57.14%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW-SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQ 756
            + PII LP+ V+  TGEE+ + L+ +R KLY+    EWKERGLG+ KIL  K   K   R +MRRE V KV  NH         S +  ++ S  W A D+++  E VKE F ++FK ++    F D +++ +
Sbjct: 2041 FSPIIPLPDKVDVKTGEEDEDMLYCQRAKLYRLVGKEWKERGLGDFKILKHKDTGK--VRFLMRREFVHKVCLNHYFSA---ELSFVVKDEKSWMWGATDYADN-EPVKEVFTLRFKCKDTAKTFMDAVENAK 2167          
BLAST of RAN binding protein 2 vs. TrEMBL
Match: E9GIT7 (Uncharacterized protein OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_304059 PE=4 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 5.475e-33
Identity = 97/285 (34.04%), Postives = 147/285 (51.58%), Query Frame = 1
Query:   67 SDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHGDNESSNEVEAVKQEPLIFG--LGNMKPDTKSSNFLF-------------------------------------PII----PQLPT--LTN---DDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            + D+V +V  + ATEEQ+++A+ L LP NF++YE      G      E ++V  +P +    +   K +T S+   F                                     PI     P  P    TN   DD  E PE+ +P ++PII LP  VE  TGEE+ E +FS R KLY++   S EWKE+G+G++KIL +K  +K +YR+++RR+Q+ K+ CNH I  +  +   M  + T+  WFA DFS+G EL+ E FA++FKTE+    FK   ++ Q  +
Sbjct: 2234 TGDEVQLVYAKEATEEQKRKAKELKLPLNFFLYEEAPPCPGCRGCEPEDKSVTTKPDVITKPIHVAKAETPSNAISFAKMIDASASQLSFSSLVSSTGSGFNKPAAFSWSGTGQPIFGMGSPATPQEDKTNHGEDDNDEVPESNDPHFEPIIPLPALVEVKTGEEDEEVIFSHRAKLYRYVAESKEWKEKGVGDIKILYNK--DKNTYRILLRRDQIHKLACNHWITDDM-SLKPMSTSTTAWTWFAMDFSQG-ELISESFAVRFKTEDQATLFKTKFEECQAAL 2514          

HSP 2 Score: 112.079 bits (279), Expect = 3.391e-24
Identity = 61/131 (46.56%), Postives = 86/131 (65.65%), Query Frame = 1
Query:  358 PDYQPIISLPE-VETITGEENSECLFSERCKLYKWS-NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTI 744
            PD++PII LPE VE  TGEE  + LF +R KL++++ N+WKERG+G++K+L   T  K   RL+MRR+QV K+  NH I  +    S+M  +  S  W A DF++G E   EKFA KFKT+E+  +FK+  
Sbjct: 1183 PDFKPIIPLPEEVEVKTGEEGEDVLFDQRAKLFRFAENQWKERGVGQLKLLQDPTTKK--VRLLMRRDQVFKICANHTITADI-KLSEMSNSPNSWIWAAMDFADG-EAKLEKFAAKFKTQEISTEFKEAF 1309          

HSP 3 Score: 106.301 bits (264), Expect = 3.145e-22
Identity = 59/137 (43.07%), Postives = 83/137 (60.58%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEK 762
            ++P+I LP  +E  TGEE  + LF +R  LY++   + EWKE+G G+MKIL  K   +   R +MRREQV K+ CNH I     +   +  +  +  W A+DFSEG ELV+E FA+KFKT +   KFK    + Q+K
Sbjct: 1742 FEPVIPLPALIEVSTGEEEEKLLFGDRAFLYRYVTETKEWKEKGRGDMKILEHKITGRT--RFLMRREQVLKICCNHYITPQL-SLKPLQTSDRTWTWSAQDFSEG-ELVQETFALKFKTMDQAQKFKGIFDEAQKK 1874          

HSP 4 Score: 100.523 bits (249), Expect = 3.997e-20
Identity = 60/141 (42.55%), Postives = 86/141 (60.99%), Query Frame = 1
Query:  328 DEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW-SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTI 744
            DEGE+    N  ++PII LPE ++  TGEE+ E ++  R KL++   NEWKERGLG++KIL  K   K   RL+MRREQ+ K+  NHA+    P  +    ++ S  W A+DF++G E  +E FAI+F+  E    F D +
Sbjct: 2084 DEGESD---NIHFEPIIPLPEKIQVKTGEEDEEVVYCHRAKLFRLVDNEWKERGLGDVKILRQKDTGKT--RLLMRREQILKICLNHALT---PELTFKPKDEKSWIWKAKDFTDGEE-KEETFAIRFRDAETCKAFMDAV 2215          
BLAST of RAN binding protein 2 vs. TrEMBL
Match: A0A2G8L3H5 (Putative E3 SUMO-protein ligase RanBP2 OS=Stichopus japonicus OX=307972 GN=BSL78_08310 PE=4 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 9.165e-33
Identity = 99/283 (34.98%), Postives = 141/283 (49.82%), Query Frame = 1
Query:   64 NSDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHG-------DNESSNEVEAVKQEPLIFGL------GNMKPDTKS-SNFLFPIIPQLPTLT---------------------------------NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
             SD+DV+ ++E  AT EQ  +A+ L LP +FY+YE+     G       D ++ N V  +  +P    L      G   P T   SN  F  +    +L+                                 ND+E E+ + ++P Y+PIISLPE V+  TG+E+ + +F ER KLY++   +N WKERG+GEMKIL  K       R++MRREQV KV  NH +  N  N   M  +  +  WFA DF+EG E   E+ A+KFKT  L   FK+T   ++E
Sbjct:  364 GSDEDVLFLAERKATPEQIAKAEKLMLPPHFYLYEDKPPCPGCRGCDEEDLKARNTVPEIGSQPEKGTLFLEKPKGPAAPTTGLFSNAAFTGV-SFASLSADGDAGFRKSDSAKPFTFANAGAQVFGAASRQDNDNETED-QEYDPHYEPIISLPENVDIKTGDEDEDVMFRERAKLYRFDRNTNAWKERGVGEMKIL--KNPETGRTRILMRREQVLKVCANHWLTPNM-NLQPMSTSDRAWLWFAADFAEGEE-SHEQLAVKFKTPNLAADFKETFDKMKE 640          

HSP 2 Score: 105.145 bits (261), Expect = 9.660e-22
Identity = 59/141 (41.84%), Postives = 92/141 (65.25%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSA---CWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++P+++LP+ V+  TGEE  E  FS R KLY++    ++WKERG+G++K+L +  +NKK +R+VMRREQV KV  NH I ++     D+  NK S     W A D S+G E+  E+ A++FKTEE   +FK+ + D ++ +
Sbjct: 1133 FEPVVTLPDNVKLETGEEGEEVKFSHRAKLYRFDMAGSQWKERGVGDIKVLFNP-ENKK-HRIVMRREQVLKVCANHYITKHV----DLQPNKGSEKSWVWHAMDVSDG-EVQNEQLAVRFKTEEAAKEFKEIVDDAKKGL 1266          
BLAST of RAN binding protein 2 vs. TrEMBL
Match: A0A2T7NTA4 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_14865 PE=4 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 1.082e-31
Identity = 101/311 (32.48%), Postives = 157/311 (50.48%), Query Frame = 1
Query:   16 NTNSDGENTNSDGENTNSDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHG-----------------DNESSNEVEAVKQEPL-------IFG---LGNM-------KPDTKSSNF-----------------LFPIIPQLPTLTNDD--------EGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW-SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            N +S G    +    T+S+DDV+++ EE  T EQ +RA+ L LPD FY+YEN     G                 D++ + +++AV +  L       +FG    G +       K D+ ++NF                 LF   P       DD        +GE   + +  ++P+I LP+ V+  TGEE+   LF  R KLY++ + +WKERG+GEMK++  K  +K  +R++MRREQV KV CNH ++        +  ++TS CW A D ++ +E   E+FAIKFK  +L  +FK   ++ QEK+
Sbjct: 2102 NLSSPGNLHTASKNFTDSEDDVVLLYEEKPTAEQVERARKLMLPDTFYLYENRPGCPGCIGCEDNLLTQSPLSKKDHQQTEKLKAVNEAALEKSTMDGVFGSRSAGTLTFSALATKADS-TANFASQGSSQPFHWHGAGQRLFGASP-----GKDDGAAGEDTADGEVAPSDDVHFEPVIPLPDLVQVKTGEEDWLPLFCHRAKLYRFDAGQWKERGIGEMKVMQHK--DKVLFRVLMRREQVLKVACNH-LINTTMALKPLATSETSWCWVANDLTD-SEPRTEQFAIKFKNADLAREFKAKFEECQEKL 2402          

HSP 2 Score: 105.916 bits (263), Expect = 5.523e-22
Identity = 65/150 (43.33%), Postives = 93/150 (62.00%), Query Frame = 1
Query:  334 GENPENFNP--DYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKF----KTEELLNKFKDTIKDL 753
            GE  E + P  D++P+I LPE VE  TGEE+   +FS R K +++   +N+WKERG+GE+KIL SK   K  +R++MRREQV KV  NH I       + + ++  + C+ A+DFSE  E+  EK AIKF    K +E  + F+D I+ L
Sbjct: 1421 GEGVEEYEPNVDFKPVIELPELVEVRTGEEDEIKIFSNRVKAFRFDSEANQWKERGVGELKILQSK--GKVRFRILMRREQVLKVCANHYISSEM-KLTPLSSSDRAWCYMAQDFSE-EEVKIEKIAIKFKDTDKAQEFRSVFEDCIRQL 1566          

HSP 3 Score: 93.2041 bits (230), Expect = 1.191e-17
Identity = 59/147 (40.14%), Postives = 83/147 (56.46%), Query Frame = 1
Query:  331 EGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSN-EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            EGE+   F   ++P++ LPE +E  TGEE+ + L   R KLY++ + EWKERG G  KIL  K   +   RL+MRR+QV K+ CNH I           A   +  W+A DFSE +E   E+ AI+F+  +   KFK   +D + KM
Sbjct: 1949 EGEDSHIF---FEPVVPLPEKIEVKTGEEDEKVLLENRAKLYRFVDGEWKERGKGVCKILEHKESGR--IRLLMRRDQVLKICCNHYITPELDLKPLPRAEGKAWVWYAMDFSE-SEGKMEQLAIRFRDADTAAKFKLVFEDSKLKM 2089          
BLAST of RAN binding protein 2 vs. Ensembl Cavefish
Match: ranbp1 (RAN binding protein 1 [Source:NCBI gene;Acc:107197224])

HSP 1 Score: 83.5741 bits (205), Expect = 4.894e-19
Identity = 52/134 (38.81%), Postives = 76/134 (56.72%), Query Frame = 1
Query:  349 NFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSN-----EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            N +P ++PI+SLPE E  T EE+ E LF  R KLY++++     EWKERG G++K+L  K   K S RL+MRR++  K+  NH I+       + G+++        DF++  E   E  AI+F   E   KFK
Sbjct:   22 NHDPHFEPIVSLPEREVKTLEEDEEELFKMRAKLYRFASENDPPEWKERGTGDVKLLRHK--EKGSIRLLMRRDRTLKICANHHIMPLMELKPNAGSDRAWVWNTHADFAD-EEPKPELLAIRFLNAENAQKFK 152          
BLAST of RAN binding protein 2 vs. Ensembl Cavefish
Match: ranbp1 (RAN binding protein 1 [Source:NCBI gene;Acc:107197224])

HSP 1 Score: 52.7582 bits (125), Expect = 5.368e-8
Identity = 37/105 (35.24%), Postives = 56/105 (53.33%), Query Frame = 1
Query:  436 ERCKLYKWSNE-----WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
             R KLY++++E     WKERG G++K+L  K   K S RL+MRR++  K+  NH I+       + G+++        DF++  E   E  AI+F   E   KFK
Sbjct:   47 RRAKLYRFASENDPPEWKERGTGDVKLLRHK--EKGSIRLLMRRDRTLKICANHHIMPLMELKPNAGSDRAWVWNTHADFAD-EEPKPELLAIRFLNAENAQKFK 148          
BLAST of RAN binding protein 2 vs. Ensembl Sea Lamprey
Match: si:ch1073-55a19.2 (RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9848])

HSP 1 Score: 99.7525 bits (247), Expect = 4.355e-24
Identity = 67/197 (34.01%), Postives = 107/197 (54.31%), Query Frame = 1
Query:  214 EAVKQEPLIFGLGNMKPDTKSSNF------LFPIIPQLPTLTNDDEGE---NPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            E    +PL FG    K  +  SNF      LF +     T   +D  E     E+    ++P++ +P+ V+ +TGEE  E  +S+R KL+++    ++WKERG+G++KIL +K   +   R++MRREQV KV  NH I  +  + + M  +  +  W A DFSEG   V E+ A+KFKT ++  +FK   ++ Q  +
Sbjct: 1755 ELATAQPLEFG----KNQSSFSNFPSIGKVLFGVTADADTSGQEDSNEMYKTEEDDEIHFEPVVQMPDKVDLVTGEEEEEVCYSQRAKLFRFDTAMSQWKERGVGDIKILRNKQTGRT--RILMRREQVLKVCANHCITTSM-SLNPMKGSDRAWVWVANDFSEGEPKV-EQLAVKFKTPDVGVEFKAKFEECQRAL 1943          

HSP 2 Score: 89.3521 bits (220), Expect = 1.800e-20
Identity = 56/142 (39.44%), Postives = 80/142 (56.34%), Query Frame = 1
Query:  346 ENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            E   P ++P++ LP+ VE  TGEE+ E L+  R KL+++   S EWKERG+G  KIL      K   R++MRREQV K+  NH I        + G++K S  W A DF++      E+ AIKFKT E    F+   ++ Q+
Sbjct: 1133 EEDGPHFEPVVPLPDKVEVKTGEEDEEELYCNRAKLFRFDADSKEWKERGVGNFKILCHHVSGK--LRVLMRREQVLKICANHYITAEMTLNRNAGSDK-SWVWHALDFADEVPR-HEQLAIKFKTAEEAVVFRTKFEEAQQ 1270          

HSP 3 Score: 81.6481 bits (200), Expect = 6.949e-18
Identity = 51/139 (36.69%), Postives = 77/139 (55.40%), Query Frame = 1
Query:  355 NPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            N  ++PI+ LP  ++  TGEE  + +F  R KLY++  E   WKERG+G++K+L    D +   RL+MRREQV K+  NH +  +      M  +  +  W A D S+G E   E  A++FK  E    F+  + D+QE
Sbjct: 2117 NLHFEPIVPLPALIDVRTGEEEEQEVFVHRAKLYRYDREAAQWKERGVGDVKLLQRLEDGRG--RLLMRREQVLKICANHWLTADT-RLEPMRGSDRAWVWNALDSSDG-EPRMEHLALRFKQLETAMVFRQAVLDIQE 2251          
BLAST of RAN binding protein 2 vs. Ensembl Sea Lamprey
Match: si:ch1073-55a19.2 (RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9848])

HSP 1 Score: 99.7525 bits (247), Expect = 4.761e-24
Identity = 67/197 (34.01%), Postives = 107/197 (54.31%), Query Frame = 1
Query:  214 EAVKQEPLIFGLGNMKPDTKSSNF------LFPIIPQLPTLTNDDEGE---NPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            E    +PL FG    K  +  SNF      LF +     T   +D  E     E+    ++P++ +P+ V+ +TGEE  E  +S+R KL+++    ++WKERG+G++KIL +K   +   R++MRREQV KV  NH I  +  + + M  +  +  W A DFSEG   V E+ A+KFKT ++  +FK   ++ Q  +
Sbjct: 1861 ELATAQPLEFG----KNQSSFSNFPSIGKVLFGVTADADTSGQEDSNEMYKTEEDDEIHFEPVVQMPDKVDLVTGEEEEEVCYSQRAKLFRFDTAMSQWKERGVGDIKILRNKQTGRT--RILMRREQVLKVCANHCITTSM-SLNPMKGSDRAWVWVANDFSEGEPKV-EQLAVKFKTPDVGVEFKAKFEECQRAL 2049          

HSP 2 Score: 89.3521 bits (220), Expect = 1.876e-20
Identity = 56/142 (39.44%), Postives = 80/142 (56.34%), Query Frame = 1
Query:  346 ENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            E   P ++P++ LP+ VE  TGEE+ E L+  R KL+++   S EWKERG+G  KIL      K   R++MRREQV K+  NH I        + G++K S  W A DF++      E+ AIKFKT E    F+   ++ Q+
Sbjct: 1133 EEDGPHFEPVVPLPDKVEVKTGEEDEEELYCNRAKLFRFDADSKEWKERGVGNFKILCHHVSGK--LRVLMRREQVLKICANHYITAEMTLNRNAGSDK-SWVWHALDFADEVPR-HEQLAIKFKTAEEAVVFRTKFEEAQQ 1270          

HSP 3 Score: 81.6481 bits (200), Expect = 7.448e-18
Identity = 51/139 (36.69%), Postives = 77/139 (55.40%), Query Frame = 1
Query:  355 NPDYQPIISLPE-VETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            N  ++PI+ LP  ++  TGEE  + +F  R KLY++  E   WKERG+G++K+L    D +   RL+MRREQV K+  NH +  +      M  +  +  W A D S+G E   E  A++FK  E    F+  + D+QE
Sbjct: 2223 NLHFEPIVPLPALIDVRTGEEEEQEVFVHRAKLYRYDREAAQWKERGVGDVKLLQRLEDGRG--RLLMRREQVLKICANHWLTADT-RLEPMRGSDRAWVWNALDSSDG-EPRMEHLALRFKQLETAMVFRQAVLDIQE 2357          
BLAST of RAN binding protein 2 vs. Ensembl Sea Lamprey
Match: si:ch1073-55a19.2 (RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9848])

HSP 1 Score: 96.6709 bits (239), Expect = 4.234e-23
Identity = 52/138 (37.68%), Postives = 87/138 (63.04%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++P++ +P+ V+ +TGEE  E  +S+R KL+++    ++WKERG+G++KIL +K   +   R++MRREQV KV  NH I  +  + + M  +  +  W A DFSEG   V E+ A+KFKT ++  +FK   ++ Q  +
Sbjct:  466 FEPVVQMPDKVDLVTGEEEEEVCYSQRAKLFRFDTAMSQWKERGVGDIKILRNKQTGRT--RILMRREQVLKVCANHCITTSM-SLNPMKGSDRAWVWVANDFSEGEPKV-EQLAVKFKTPDVGVEFKAKFEECQRAL 599          

HSP 2 Score: 87.0409 bits (214), Expect = 7.757e-20
Identity = 55/139 (39.57%), Postives = 82/139 (58.99%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++P++ LP+ VE  TGEE+ E L+  R KL+++   S EWKERG+G  KIL      K   R++MRREQV K+  NH I        + G++K S  W A DF++  E+ + E+ AIKFKT E    F+   ++ Q+ +
Sbjct:    1 FEPVVPLPDKVEVKTGEEDEEELYCNRAKLFRFDADSKEWKERGVGNFKILCHHVSGK--LRVLMRREQVLKICANHYITAEMTLNRNAGSDK-SWVWHALDFAD--EVPRHEQLAIKFKTAEEAVVFRTKFEEAQQLL 134          
BLAST of RAN binding protein 2 vs. Ensembl Yeast
Match: YRB1 (Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1 [Source:SGD;Acc:S000002409])

HSP 1 Score: 79.7221 bits (195), Expect = 1.067e-18
Identity = 50/147 (34.01%), Postives = 86/147 (58.50%), Query Frame = 1
Query:  331 EGEN-PENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            EG++ PE+ +  ++P++ L +V+  T EE+ E L+  R KL+++   + EWKERG G+ K L +K  NK   R++MRR++  K+  NH I        ++G++++       D +EG E     FAI+F ++E  +KFK+  +  QE
Sbjct:   53 EGDDAPESPDIHFEPVVHLEKVDVKTMEEDEEVLYKVRAKLFRFDADAKEWKERGTGDCKFLKNKKTNK--VRILMRRDKTLKICANHIIAPEYTLKPNVGSDRSWVYACTADIAEG-EAEAFTFAIRFGSKENADKFKEEFEKAQE 196          
BLAST of RAN binding protein 2 vs. Ensembl Yeast
Match: YRB2 (Protein of unknown function; involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; relocalizes to the cytosol in response to hypoxia; not essential for viability [Source:SGD;Acc:S000001325])

HSP 1 Score: 58.9214 bits (141), Expect = 1.191e-10
Identity = 32/76 (42.11%), Postives = 48/76 (63.16%), Query Frame = 1
Query:  376 ISLPEVETITGEENSECLFSERCKLYKWSN---EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQ 594
            + L + E  +GEE+ EC++    KLY+ SN    WKERG+G +KI  SK D +K+ R+VMR   + KV+ N  +V+
Sbjct:  198 LKLQKQEVKSGEESEECIYQVNAKLYQLSNIKEGWKERGVGIIKINKSKDDVEKT-RIVMRSRGILKVILNIQLVK 272          
BLAST of RAN binding protein 2 vs. Ensembl Yeast
Match: NUP2 (Nucleoporin involved in nucleocytoplasmic transport; binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization [Source:SGD;Acc:S000004327])

HSP 1 Score: 48.1358 bits (113), Expect = 5.681e-7
Identity = 40/125 (32.00%), Postives = 62/125 (49.60%), Query Frame = 1
Query:  406 GEENSECLFSERCKLYKWSNEWKE---RGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCP--NFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            GEE+   LFS++ KL  ++ E K    RG+GEMK+L  K D  K  RL+ R + +  V+ N  +V +      +    N   A   A D     +LV   + +KFK +E    F   I+D +++M
Sbjct:  602 GEEDEVALFSQKAKLMTFNAETKSYDSRGVGEMKLLKKKDDPSK-VRLLCRSDGMGNVLLNATVVDSFKYEPLAPGNDNLIKAPTVAAD----GKLV--TYIVKFKQKEEGRSFTKAIEDAKKEM 719          
BLAST of RAN binding protein 2 vs. Ensembl Nematostella
Match: EDO37940 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEF1])

HSP 1 Score: 110.538 bits (275), Expect = 1.596e-30
Identity = 59/139 (42.45%), Postives = 89/139 (64.03%), Query Frame = 1
Query:  361 DYQPIISLPEVETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFA-EDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            D+ P++SLP+VE +TGEEN E LFS R KLY++   SN+WKERG+G++KIL + TD K   R++MRR+Q+RK+  NH I         M  +  +  W +  D SE    V E+ A+KFK+  + ++FKD  +  Q+++
Sbjct:    2 DFAPLVSLPKVEVVTGEENEEALFSHRAKLYRYDKDSNQWKERGVGDIKILKNATDQK--CRILMRRDQIRKLCANHNITSEI-KLLPMSTSDRAWVWTSLADLSEEEPKV-EQLAVKFKSPSVAHQFKDVFEKAQQRL 136          
BLAST of RAN binding protein 2 vs. Ensembl Nematostella
Match: EDO37944 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEF5])

HSP 1 Score: 91.6633 bits (226), Expect = 2.569e-23
Identity = 54/141 (38.30%), Postives = 84/141 (59.57%), Query Frame = 1
Query:  346 ENFNPDYQPIISLP-EVETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQ 756
            E  +  ++P+I LP  V+ +TGEEN E +FS R KLY+++     WKERG+G++K+L      K   R++MRR+Q+ K+  NH I  +    S+MG++++       DFSE  E   E+ AI+FK  E   KFK+   +L+
Sbjct:    2 EEADAHFKPVIPLPARVQVVTGEENHEVMFSGRAKLYRFNVDLKAWKERGVGDIKLLRDLKSGKG--RVIMRRDQIYKLCANHWIKPDMELKSNMGSDRSWVWNTLADFSE-EEPSAEQLAIRFKLPETATKFKEAFDELK 139          
BLAST of RAN binding protein 2 vs. Ensembl Nematostella
Match: EDO37942 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEF3])

HSP 1 Score: 88.1965 bits (217), Expect = 3.864e-22
Identity = 48/133 (36.09%), Postives = 82/133 (61.65%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKD 750
            ++PII LPE +E  TGEE+ + LFS R KLY++   + +WKERG+G++K+L++    +   R++MRR+QV K+  NH +  +     + G++K+       D++E  E   E+FA++FK  E    F+ T ++
Sbjct:    2 FEPIIPLPEKIEVKTGEEHEKALFSHRAKLYRYDSNAKQWKERGIGDIKLLSNPQTGR--VRVLMRRDQVLKICANHLLTPDMTIKPNAGSDKSLVWSTVADYAE-EESKPEQFAVRFKHAETATLFRKTFEE 131          
BLAST of RAN binding protein 2 vs. Ensembl Nematostella
Match: EDO41916 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S303])

HSP 1 Score: 90.5077 bits (223), Expect = 4.243e-22
Identity = 52/139 (37.41%), Postives = 81/139 (58.27%), Query Frame = 1
Query:  364 YQPIISLPEVETITGEENSECLFSERCKLYKWS-----NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            ++PI++LP++E  + EEN E +F  R KLY++      N WKERG+G ++IL  K   K +YR++MRR++  K+  NH I        + G+++        DF++  E+  E  AIKF   E  NKFKD  +D Q+K+
Sbjct:   20 FKPIVNLPKIELKSQEENEEEIFQMRAKLYRYDTAGDENLWKERGVGNVRILKHKL-KKHTYRVLMRRDKTLKICANHLIDPEMELKVNCGSDRAWVWSVKADFAD-EEVKPETLAIKFANAENANKFKDVFQDCQKKI 156          
BLAST of RAN binding protein 2 vs. Ensembl Nematostella
Match: EDO37943 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEF4])

HSP 1 Score: 88.1965 bits (217), Expect = 1.177e-21
Identity = 60/159 (37.74%), Postives = 85/159 (53.46%), Query Frame = 1
Query:  298 IPQLPT-LTNDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLY---KWSNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQE 759
            +P+ PT  T+       E+  P ++P+I+LP+ +E  TGEE    ++S R KLY   K S +WKERGLG++KIL  K       R++MRRE V K+  NH I          G ++        DFS+  E  KE FAI+FKT  +   FK   +D +E
Sbjct:    9 VPETPTSPTSPGAASECEDDGPHFEPVIALPKKIEVRTGEEEEVIVYSHRAKLYRHDKESAQWKERGLGDVKIL--KNPRTLKCRVLMRRENVLKICANHQITPVMHLEPMRGCDRAWVWHVLADFSD-EEQKKELFAIRFKTVGIAQDFKKAFEDARE 164          
BLAST of RAN binding protein 2 vs. Ensembl Medaka
Match: si:ch1073-55a19.2 (RANBP2-like and GRIP domain-containing protein 8 [Source:NCBI gene;Acc:101160447])

HSP 1 Score: 129.413 bits (324), Expect = 1.659e-33
Identity = 76/185 (41.08%), Postives = 105/185 (56.76%), Query Frame = 1
Query:  241 FGLGNMKPDTKSSN-----FLFPII--PQLPTLTNDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            F  GN   D   +N     F  P+   P+  T    DE E P N +  ++PI+SLPEVET +GEE+ E LF ER KLY+W  +   WKERG+G++KIL     NK+ YR++MRR+QV +V  NH I+Q       +     +  W A D+++G E V E+ A KFKT E+   FK T  + Q +M
Sbjct: 2740 FAFGNKDSDFSWANAGAMVFKPPVSCEPKPKTDDGSDEEEAPTNVDIHFEPIVSLPEVETKSGEEDEEILFKERAKLYRWDRDQSMWKERGIGDIKILFHP--NKRFYRILMRRDQVLRVCANHTIIQGM-ELKPLNTTANAVVWTATDYADG-EGVVEQLAAKFKTPEIAETFKKTFCECQSRM 2920          

HSP 2 Score: 98.5969 bits (244), Expect = 6.369e-23
Identity = 52/144 (36.11%), Postives = 89/144 (61.81%), Query Frame = 1
Query:  346 ENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            EN +  ++P++ +P+ V+ +TGEE+ + L+S+R KL+++   +++WKERG+G +K L +  + +   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A+KFKT EL  +FK   ++ Q  +
Sbjct: 1931 ENDDIQFEPVVQMPDKVDVVTGEEDEQVLYSQRVKLFRFDTSTSQWKERGVGVLKFLKNSINGR--LRVLMRREQVLKVCANHWITTTM-NLKPLAGSDKAWIWLANDFSDGDAKL-EQLAVKFKTPELAEEFKAKFEECQRLL 2070          

HSP 3 Score: 97.8265 bits (242), Expect = 1.084e-22
Identity = 53/133 (39.85%), Postives = 80/133 (60.15%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKD 750
            ++P++ LP+ VE  TGEEN + +FS R KLY++     +WKERG+G++KIL  +  + K  RL+MRR+QV K+  NH I +       M   + +  W A DFSE  E   E+ A++FK +E  N FK   ++
Sbjct: 2233 FEPVVPLPDLVEVSTGEENEQSIFSHRAKLYRFDKDVGQWKERGIGDLKIL--QNYDSKRVRLIMRRDQVLKLCANHWISETM-KLEPMKGAEKAWVWSAMDFSEDGEGKIEQLAVRFKLQETANTFKQVFEE 2362          

HSP 4 Score: 86.6557 bits (213), Expect = 6.994e-19
Identity = 58/142 (40.85%), Postives = 84/142 (59.15%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            ND    + +   P ++PI+ LP+ V+  TGEE  E +F  R KLY++   + EWKERG+G +KIL  K + K   RL+MRREQV K+  NH I  +     + G++K S  W A D+++  E   E+ AI+FKT E  + FK
Sbjct: 1157 NDSAHADEDEDGPHFEPIVPLPDKVDVKTGEEEEEEMFCNRAKLYRFDAETKEWKERGIGNLKIL--KHNTKGKVRLLMRREQVLKICANHYITADMLLKPNAGSDK-SWVWNAIDYAD-EEPKPEQLAIRFKTVEEASLFK 1294          
BLAST of RAN binding protein 2 vs. Ensembl Medaka
Match: si:ch1073-55a19.2 (RANBP2-like and GRIP domain-containing protein 8 [Source:NCBI gene;Acc:101160447])

HSP 1 Score: 129.413 bits (324), Expect = 1.692e-33
Identity = 76/185 (41.08%), Postives = 105/185 (56.76%), Query Frame = 1
Query:  241 FGLGNMKPDTKSSN-----FLFPII--PQLPTLTNDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSNE---WKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            F  GN   D   +N     F  P+   P+  T    DE E P N +  ++PI+SLPEVET +GEE+ E LF ER KLY+W  +   WKERG+G++KIL     NK+ YR++MRR+QV +V  NH I+Q       +     +  W A D+++G E V E+ A KFKT E+   FK T  + Q +M
Sbjct: 2767 FAFGNKDSDFSWANAGAMVFKPPVSCEPKPKTDDGSDEEEAPTNVDIHFEPIVSLPEVETKSGEEDEEILFKERAKLYRWDRDQSMWKERGIGDIKILFHP--NKRFYRILMRRDQVLRVCANHTIIQGM-ELKPLNTTANAVVWTATDYADG-EGVVEQLAAKFKTPEIAETFKKTFCECQSRM 2947          

HSP 2 Score: 98.5969 bits (244), Expect = 6.193e-23
Identity = 52/144 (36.11%), Postives = 89/144 (61.81%), Query Frame = 1
Query:  346 ENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            EN +  ++P++ +P+ V+ +TGEE+ + L+S+R KL+++   +++WKERG+G +K L +  + +   R++MRREQV KV  NH I     N   +  +  +  W A DFS+G   + E+ A+KFKT EL  +FK   ++ Q  +
Sbjct: 1931 ENDDIQFEPVVQMPDKVDVVTGEEDEQVLYSQRVKLFRFDTSTSQWKERGVGVLKFLKNSINGR--LRVLMRREQVLKVCANHWITTTM-NLKPLAGSDKAWIWLANDFSDGDAKL-EQLAVKFKTPELAEEFKAKFEECQRLL 2070          

HSP 3 Score: 97.8265 bits (242), Expect = 1.054e-22
Identity = 53/133 (39.85%), Postives = 80/133 (60.15%), Query Frame = 1
Query:  364 YQPIISLPE-VETITGEENSECLFSERCKLYKWS---NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKD 750
            ++P++ LP+ VE  TGEEN + +FS R KLY++     +WKERG+G++KIL  +  + K  RL+MRR+QV K+  NH I +       M   + +  W A DFSE  E   E+ A++FK +E  N FK   ++
Sbjct: 2233 FEPVVPLPDLVEVSTGEENEQSIFSHRAKLYRFDKDVGQWKERGIGDLKIL--QNYDSKRVRLIMRRDQVLKLCANHWISETM-KLEPMKGAEKAWVWSAMDFSEDGEGKIEQLAVRFKLQETANTFKQVFEE 2362          

HSP 4 Score: 86.6557 bits (213), Expect = 7.476e-19
Identity = 58/142 (40.85%), Postives = 84/142 (59.15%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPE-VETITGEENSECLFSERCKLYKW---SNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFK 735
            ND    + +   P ++PI+ LP+ V+  TGEE  E +F  R KLY++   + EWKERG+G +KIL  K + K   RL+MRREQV K+  NH I  +     + G++K S  W A D+++  E   E+ AI+FKT E  + FK
Sbjct: 1157 NDSAHADEDEDGPHFEPIVPLPDKVDVKTGEEEEEEMFCNRAKLYRFDAETKEWKERGIGNLKIL--KHNTKGKVRLLMRREQVLKICANHYITADMLLKPNAGSDK-SWVWNAIDYAD-EEPKPEQLAIRFKTVEEASLFK 1294          
BLAST of RAN binding protein 2 vs. Ensembl Medaka
Match: ranbp1 (RAN binding protein 1 [Source:NCBI gene;Acc:101155441])

HSP 1 Score: 80.4925 bits (197), Expect = 6.512e-18
Identity = 51/135 (37.78%), Postives = 77/135 (57.04%), Query Frame = 1
Query:  349 NFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSN-----EWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVK-EKFAIKFKTEELLNKFK 735
            N +P ++PI+SLPE +  T EE+ E LF  R KLY++++     EWKERG G++K+L  K   K + RL+MRR++  K+  NH IV       + G+++        D+++  E  K E  AI+F   E   KFK
Sbjct:   21 NHDPHFEPIVSLPEQDVKTLEEDEEELFKMRAKLYRFASENDPPEWKERGTGDVKLLKHK--EKGTIRLLMRRDRTLKICANHNIVPTMELKPNAGSDRAWVWNTLADYAD--ECPKPELLAIRFLNAENAQKFK 151          
BLAST of RAN binding protein 2 vs. Planmine SMEST
Match: SMESG000031772.1 (SMESG000031772.1)

HSP 1 Score: 527.324 bits (1357), Expect = 7.570e-178
Identity = 253/255 (99.22%), Postives = 253/255 (99.22%), Query Frame = 1
Query:    1 NSDGENTNSDGENTNSDGENTNSDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHGDNESSNEVEAVKQEPLIFGLGNMKPDTKSSNFLFPIIPQLPTLTNDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            NSD ENTNSDGENTNSDGENTNSDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHGDNESSNEVEAVKQEPLIFGLGNMKPDTKSSNFLFPIIPQLPTLTNDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANK SACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM
Sbjct: 1196 NSDSENTNSDGENTNSDGENTNSDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHGDNESSNEVEAVKQEPLIFGLGNMKPDTKSSNFLFPIIPQLPTLTNDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKASACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 1450          
BLAST of RAN binding protein 2 vs. Planmine SMEST
Match: SMESG000031772.1 (SMESG000031772.1)

HSP 1 Score: 527.709 bits (1358), Expect = 1.015e-177
Identity = 253/255 (99.22%), Postives = 253/255 (99.22%), Query Frame = 1
Query:    1 NSDGENTNSDGENTNSDGENTNSDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHGDNESSNEVEAVKQEPLIFGLGNMKPDTKSSNFLFPIIPQLPTLTNDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            NSD ENTNSDGENTNSDGENTNSDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHGDNESSNEVEAVKQEPLIFGLGNMKPDTKSSNFLFPIIPQLPTLTNDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANK SACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM
Sbjct: 1221 NSDSENTNSDGENTNSDGENTNSDDDVIIVSEEYATEEQRKRAQLLFLPDNFYVYENYSSLHGDNESSNEVEAVKQEPLIFGLGNMKPDTKSSNFLFPIIPQLPTLTNDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWSNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKASACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 1475          
BLAST of RAN binding protein 2 vs. Planmine SMEST
Match: SMESG000078741.1 (SMESG000078741.1)

HSP 1 Score: 139.043 bits (349), Expect = 3.812e-37
Identity = 71/144 (49.31%), Postives = 96/144 (66.67%), Query Frame = 1
Query:  346 ENFNPDYQPIISLPEVETITG-EENSECLFSERCKLYKW-SNEWKERGLGEMKILASK--TDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKDLQEKM 765
            E  +P +QPII LP + ++   EE  + LF  RCKLY++ +NEWKERG+GEMKIL +K   D  K  +LVMRR+QVRK+ CN  + +N P F++M  N  S CW   DFSEG E  +EKFAI+F   + LNKFK  ++ +Q +M
Sbjct:  708 EEHDPHFQPIIDLPPLVSVQKDEELHDVLFRSRCKLYRFINNEWKERGVGEMKILQTKESVDQSKPVKLVMRRDQVRKICCNQRVSKNVPAFTEM-PNVKSTCWVGNDFSEG-EPAQEKFAIRFAHVDELNKFKGIVEKIQSEM 849          
BLAST of RAN binding protein 2 vs. Planmine SMEST
Match: SMESG000010762.1 (SMESG000010762.1)

HSP 1 Score: 70.4774 bits (171), Expect = 4.738e-15
Identity = 51/138 (36.96%), Postives = 76/138 (55.07%), Query Frame = 1
Query:  322 NDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKLYKWS-----NEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNCPNFSDMGANKTSACWF-AEDFSEGTELVKEKFAIKFKTEE 717
            +DDE    E    D+ P+++LP V  I   E++E +F +    Y +      NEWKERG+G+++IL  K + K  YR++MRR QV+KV  NH +V N     +     T+  W+ A D+S+   L    FA KF T+E
Sbjct:    2 SDDENIETER---DFAPVVNLPLV--INETEDAEVIFEKEVTAYIYDMVVMPNEWKERGVGKLRIL--KENEKGRYRILMRRNQVKKVCLNH-LVHNHFRIVNHQKKNTTLVWYTARDWSDEV-LENCCFAAKFSTKE 130          
The following BLAST results are available for this feature:
BLAST of RAN binding protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RANBP22.188e-2739.87RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC... [more]
RGPD88.762e-2337.50RANBP2 like and GRIP domain containing 8 [Source:H... [more]
RGPD68.930e-2337.50RANBP2 like and GRIP domain containing 6 [Source:H... [more]
RGPD58.930e-2337.50RANBP2 like and GRIP domain containing 5 [Source:H... [more]
RGPD89.011e-2337.50RANBP2 like and GRIP domain containing 8 [Source:H... [more]
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BLAST of RAN binding protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
npp-91.533e-2241.86Nuclear Pore complex Protein [Source:UniProtKB/Tr... [more]
npp-91.533e-2241.86Nuclear Pore complex Protein [Source:UniProtKB/Tr... [more]
npp-91.533e-2241.86Nuclear Pore complex Protein [Source:UniProtKB/Tr... [more]
npp-97.681e-2242.76Nuclear Pore complex Protein [Source:UniProtKB/Tr... [more]
npp-97.681e-2242.76Nuclear Pore complex Protein [Source:UniProtKB/Tr... [more]
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BLAST of RAN binding protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Nup3583.650e-2740.58gene:FBgn0039302 transcript:FBtr0084813[more]
Nup3583.905e-2740.41gene:FBgn0039302 transcript:FBtr0304692[more]
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BLAST of RAN binding protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RANBP21.101e-2945.39si:ch1073-55a19.2 [Source:ZFIN;Acc:ZDB-GENE-081104... [more]
RANBP21.167e-2945.39si:ch1073-55a19.2 [Source:ZFIN;Acc:ZDB-GENE-081104... [more]
RANBP21.236e-2945.39si:ch1073-55a19.2 [Source:ZFIN;Acc:ZDB-GENE-081104... [more]
ftr52p1.881e-2136.31finTRIM family, member 52, pseudogene [Source:ZFIN... [more]
ranbp16.179e-1837.31RAN binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
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BLAST of RAN binding protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mcoln23.231e-2942.48mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908][more]
mcoln23.237e-2942.48mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908][more]
mcoln23.323e-2942.48mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908][more]
mcoln23.484e-2942.48mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908][more]
mcoln23.955e-2942.48mucolipin 2 [Source:Xenbase;Acc:XB-GENE-5767908][more]
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BLAST of RAN binding protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ranbp21.348e-2741.61RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:8... [more]
Ranbp16.167e-1735.10RAN binding protein 1 [Source:MGI Symbol;Acc:MGI:9... [more]
Ranbp16.167e-1735.10RAN binding protein 1 [Source:MGI Symbol;Acc:MGI:9... [more]
Ranbp12.529e-631.40RAN binding protein 1 [Source:MGI Symbol;Acc:MGI:9... [more]
Ranbp12.529e-631.40RAN binding protein 1 [Source:MGI Symbol;Acc:MGI:9... [more]
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BLAST of RAN binding protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9ERU9|RBP2_MOUSE9.428e-2741.61E3 SUMO-protein ligase RanBP2 OS=Mus musculus OX=1... [more]
sp|H2QII6|RBP2_PANTR9.643e-2739.87E3 SUMO-protein ligase RanBP2 OS=Pan troglodytes O... [more]
sp|P49792|RBP2_HUMAN1.051e-2639.87E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9... [more]
sp|A0A0B4K7J2|RBP2_DROME3.914e-2640.41E3 SUMO-protein ligase RanBP2 OS=Drosophila melano... [more]
sp|P48820|RBP2_BOVIN8.070e-2639.42E3 SUMO-protein ligase RanBP2 (Fragment) OS=Bos ta... [more]
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BLAST of RAN binding protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0F7GYG22.403e-3449.31RAN binding protein 2 (Fragment) OS=Schmidtea medi... [more]
T1IZQ71.129e-3335.19Uncharacterized protein OS=Strigamia maritima OX=1... [more]
E9GIT75.475e-3334.04Uncharacterized protein OS=Daphnia pulex OX=6669 G... [more]
A0A2G8L3H59.165e-3334.98Putative E3 SUMO-protein ligase RanBP2 OS=Stichopu... [more]
A0A2T7NTA41.082e-3132.48Uncharacterized protein OS=Pomacea canaliculata OX... [more]
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BLAST of RAN binding protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ranbp14.894e-1938.81RAN binding protein 1 [Source:NCBI gene;Acc:107197... [more]
ranbp15.368e-835.24RAN binding protein 1 [Source:NCBI gene;Acc:107197... [more]
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BLAST of RAN binding protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
si:ch1073-55a19.24.355e-2434.01RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC... [more]
si:ch1073-55a19.24.761e-2434.01RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC... [more]
si:ch1073-55a19.24.234e-2337.68RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of RAN binding protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
YRB11.067e-1834.01Ran GTPase binding protein; involved in nuclear pr... [more]
YRB21.191e-1042.11Protein of unknown function; involved in nuclear p... [more]
NUP25.681e-732.00Nucleoporin involved in nucleocytoplasmic transpor... [more]
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BLAST of RAN binding protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO379401.596e-3042.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO379442.569e-2338.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO379423.864e-2236.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO419164.243e-2237.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO379431.177e-2137.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of RAN binding protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
si:ch1073-55a19.21.659e-3341.08RANBP2-like and GRIP domain-containing protein 8 [... [more]
si:ch1073-55a19.21.692e-3341.08RANBP2-like and GRIP domain-containing protein 8 [... [more]
ranbp16.512e-1837.78RAN binding protein 1 [Source:NCBI gene;Acc:101155... [more]
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BLAST of RAN binding protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000031772.17.570e-17899.22SMESG000031772.1[more]
SMESG000031772.11.015e-17799.22SMESG000031772.1[more]
SMESG000078741.13.812e-3749.31SMESG000078741.1[more]
SMESG000010762.14.738e-1536.96SMESG000010762.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006518 ID=SMED30006518|Name=RAN binding protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=773bp
AACAGTGATGGTGAAAACACAAACAGTGATGGTGAAAACACAAACAGTGA
TGGTGAAAACACAAATAGCGATGATGATGTTATTATAGTGTCTGAAGAGT
ATGCAACAGAAGAACAAAGGAAACGAGCCCAATTATTATTTCTCCCGGAT
AATTTCTATGTCTATGAAAATTATTCCAGTCTTCACGGTGACAACGAGTC
ATCCAATGAAGTTGAAGCAGTCAAACAAGAACCCCTAATTTTTGGGTTAG
GAAATATGAAACCCGATACAAAATCTTCCAATTTTTTATTTCCAATAATT
CCTCAATTGCCGACTCTAACCAATGACGATGAAGGTGAAAACCCGGAAAA
TTTTAATCCAGACTATCAACCAATCATCTCTTTGCCTGAAGTCGAAACCA
TCACCGGTGAAGAGAATTCTGAATGCCTATTTAGTGAACGATGCAAACTT
TATAAGTGGTCCAATGAGTGGAAAGAACGCGGACTTGGTGAGATGAAAAT
ATTGGCCTCAAAAACCGACAATAAAAAGTCATACAGATTGGTTATGAGAC
GAGAACAGGTTCGTAAAGTTGTTTGTAACCATGCCATTGTCCAGAACTGC
CCGAATTTCTCAGACATGGGGGCCAATAAAACGAGCGCTTGTTGGTTTGC
AGAAGACTTCAGTGAAGGAACAGAATTAGTCAAAGAAAAGTTCGCAATTA
AATTCAAAACGGAAGAACTGTTAAACAAATTCAAAGATACGATTAAAGAT
TTGCAAGAGAAAATGTAAATGAG
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protein sequence of SMED30006518-orf-1

>SMED30006518-orf-1 ID=SMED30006518-orf-1|Name=SMED30006518-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=256bp
NSDGENTNSDGENTNSDGENTNSDDDVIIVSEEYATEEQRKRAQLLFLPD
NFYVYENYSSLHGDNESSNEVEAVKQEPLIFGLGNMKPDTKSSNFLFPII
PQLPTLTNDDEGENPENFNPDYQPIISLPEVETITGEENSECLFSERCKL
YKWSNEWKERGLGEMKILASKTDNKKSYRLVMRREQVRKVVCNHAIVQNC
PNFSDMGANKTSACWFAEDFSEGTELVKEKFAIKFKTEELLNKFKDTIKD
LQEKM*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR000156Ran_bind_dom
IPR011993PH-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0046907intracellular transport
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0016874ligase activity
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 230..250
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..23
NoneNo IPR availablePANTHERPTHR23138RAN BINDING PROTEINcoord: 100..248
NoneNo IPR availablePANTHERPTHR23138:SF139coord: 100..248
NoneNo IPR availableCDDcd00835RanBD_familycoord: 131..248
e-value: 2.72541E-43
score: 140.81
NoneNo IPR availableSUPERFAMILYSSF50729PH domain-likecoord: 115..251
IPR000156Ran binding domainSMARTSM00160ranbd_3coord: 118..247
e-value: 2.2E-35
score: 133.6
IPR000156Ran binding domainPFAMPF00638Ran_BP1coord: 130..249
e-value: 6.5E-29
score: 100.7
IPR000156Ran binding domainPROSITEPS50196RANBD1coord: 117..251
score: 28.087
IPR011993PH-like domain superfamilyGENE3DG3DSA:2.30.29.30coord: 103..251
e-value: 5.5E-45
score: 154.7