Histone acetyltransferase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30006506 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Histone acetyltransferase vs. Ensembl Human
Match: KAT5 (lysine acetyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:5275]) HSP 1 Score: 443.351 bits (1139), Expect = 4.584e-148 Identity = 239/500 (47.80%), Postives = 324/500 (64.80%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSAL---KNEDQMSLVTMDDR----NCFSYLQEP------VANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+ + T SP E ++ E V + S T+ +++ + ++ R NC ++ + + TGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 38 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKE------AKTPTKNGLPGSRPGSPEREVK-RKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLV--SDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 494
BLAST of Histone acetyltransferase vs. Ensembl Human
Match: KAT5 (lysine acetyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:5275]) HSP 1 Score: 441.81 bits (1135), Expect = 5.276e-148 Identity = 239/500 (47.80%), Postives = 324/500 (64.80%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSAL---KNEDQMSLVTMDDR----NCFSYLQEP------VANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+ + T SP E ++ E V + S T+ +++ + ++ R NC ++ + + TGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKE------AKTPTKNGLPGSRPGSPEREVK-RKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLV--SDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 461
BLAST of Histone acetyltransferase vs. Ensembl Human
Match: KAT5 (lysine acetyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:5275]) HSP 1 Score: 409.838 bits (1052), Expect = 6.021e-138 Identity = 202/335 (60.30%), Postives = 252/335 (75.22%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 2 TGSLV--SDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 302
BLAST of Histone acetyltransferase vs. Ensembl Human
Match: KAT5 (lysine acetyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:5275]) HSP 1 Score: 412.535 bits (1059), Expect = 7.977e-136 Identity = 202/335 (60.30%), Postives = 252/335 (75.22%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 213 TGSLV--SDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 513 HSP 2 Score: 53.1434 bits (126), Expect = 1.498e-6 Identity = 26/72 (36.11%), Postives = 46/72 (63.89%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKE 74
BLAST of Histone acetyltransferase vs. Ensembl Human
Match: KAT5 (lysine acetyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:5275]) HSP 1 Score: 413.305 bits (1061), Expect = 9.120e-136 Identity = 202/335 (60.30%), Postives = 252/335 (75.22%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 246 TGSLV--SDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 546
BLAST of Histone acetyltransferase vs. Ensembl Celegans
Match: mys-1 (Histone acetyltransferase Tip60 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q9TYU5]) HSP 1 Score: 395.971 bits (1016), Expect = 1.110e-130 Identity = 220/492 (44.72%), Postives = 294/492 (59.76%), Query Frame = 2
Query: 23 FNKLCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQT--------GSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVT--KKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKR 1468
+ K+ EG +L V + + +AE++ +R G+ ++YVH+ + N+RLD+WV DR+ + P K K + E N EN K S K ++ L+ MDD S +P+ + T GSM + H E D +TR+RN++ I LG+SRI+PWYF+PYP++LT LD I+ICEFCLKY KS CL+RH+EKC + HPPGN+IY + LSFFEIDGRKNK YAQNLCLLAKLFLDHKTLYYDTDPFLFY+L E DE+G HIVGYFSKEKES ++ NVACIL LPP+Q+KGYG LLIEFSYELSK+E KTGSPEKPLSDLGLLSYRSYW IM+ + + F P + + D+ + TSI +D+ +TL +++ Y KG ++IV++ K+ + + + AK+K RI+ L W PK++ K+
Sbjct: 27 YEKVTEGCRLLVMMASQEEERWAEVI-SRCRAANGSIKFYVHYIDCNRRLDEWVQSDRLNLASCELPKKGGKK-----------------GAHLREENRDSNENEGKK---------SGRKR--KIPLLPMDDLKAESV--DPLQAISTMTSGSTPSLRGSMSMVGHSE--DAMTRIRNVECIELGRSRIQPWYFAPYPQQLTSLDCIYICEFCLKYLKSKTCLKRHMEKCAMCHPPGNQIYSHDKLSFFEIDGRKNKSYAQNLCLLAKLFLDHKTLYYDTDPFLFYVLTEEDEKGHHIVGYFSKEKESAEEYNVACILVLPPFQKKGYGSLLIEFSYELSKIEQKTGSPEKPLSDLGLLSYRSYWSMAIMKEL--------------------------FAFKRRHPGEDITV-------QDISQSTSIKREDVVSTLQQLDLYKYYKGSYIIVISDEKRQVYEKRIEAAKKKTRINPAALQWRPKEYGKK 452
BLAST of Histone acetyltransferase vs. Ensembl Celegans
Match: mys-2 (Histone acetyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A131MBB1]) HSP 1 Score: 262.307 bits (669), Expect = 1.062e-78 Identity = 145/344 (42.15%), Postives = 207/344 (60.17%), Query Frame = 2
Query: 101 KARENKRLGTKE--YYVHFDEYNKRLDDWVSEDRMKMHEMVF-PTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSST--SSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEV 1117
K+ EN G KE YYVH++E ++R D+W++ D++ ++E+V P K+ E++ +I + S AL + +L +S+L+ + N L T + + H+E T+++NI I +G I WY+SP+P + LD I++CE+CL Y ++H++ C++R PPGNEIYRK+ LS +E+DG K Y Q LCLL+KLF+DHKTLY+D D F+FY+LCE DE G HIVGYFS+E ES NN+ACI+ PP+Q+KGYGKLLI+FSYELS+ E G PEKPLSDLG +SYRSYW +M++
Sbjct: 75 KSIENHEQGAKELMYYVHYEELDRRNDEWITLDKILVNEVVVEPVIKV-------------------------PTKAPVEDLHKEIVVGPPVIKPSGALTRSQRRTL------EEYSHLKTDL-NDLDATTARLEREHEER----TKVKNIPQITIGAHEILAWYYSPFPPDCENLD-IYMCEYCLLYTPHHERFKQHIDTCKVRQPPGNEIYRKDHLSVYEVDGSGQKLYCQCLCLLSKLFMDHKTLYFDVDDFMFYVLCETDEHGAHIVGYFSREVESA--NNLACIMVFPPFQKKGYGKLLIQFSYELSRREGYIGMPEKPLSDLGKVSYRSYWWWRLMKL 379
BLAST of Histone acetyltransferase vs. Ensembl Celegans
Match: mys-2 (Histone acetyltransferase [Source:UniProtKB/TrEMBL;Acc:A0A131MBB1]) HSP 1 Score: 262.692 bits (670), Expect = 1.122e-78 Identity = 145/344 (42.15%), Postives = 207/344 (60.17%), Query Frame = 2
Query: 101 KARENKRLGTKE--YYVHFDEYNKRLDDWVSEDRMKMHEMVF-PTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSST--SSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEV 1117
K+ EN G KE YYVH++E ++R D+W++ D++ ++E+V P K+ E++ +I + S AL + +L +S+L+ + N L T + + H+E T+++NI I +G I WY+SP+P + LD I++CE+CL Y ++H++ C++R PPGNEIYRK+ LS +E+DG K Y Q LCLL+KLF+DHKTLY+D D F+FY+LCE DE G HIVGYFS+E ES NN+ACI+ PP+Q+KGYGKLLI+FSYELS+ E G PEKPLSDLG +SYRSYW +M++
Sbjct: 75 KSIENHEQGAKELMYYVHYEELDRRNDEWITLDKILVNEVVVEPVIKV-------------------------PTKAPVEDLHKEIVVGPPVIKPSGALTRSQRRTLEE------YSHLKTDL-NDLDATTARLEREHEER----TKVKNIPQITIGAHEILAWYYSPFPPDCENLD-IYMCEYCLLYTPHHERFKQHIDTCKVRQPPGNEIYRKDHLSVYEVDGSGQKLYCQCLCLLSKLFMDHKTLYFDVDDFMFYVLCETDEHGAHIVGYFSREVESA--NNLACIMVFPPFQKKGYGKLLIQFSYELSRREGYIGMPEKPLSDLGKVSYRSYWWWRLMKL 379
BLAST of Histone acetyltransferase vs. Ensembl Celegans
Match: lsy-12 (Histone acetyltransferase [Source:UniProtKB/TrEMBL;Acc:L8E6K3]) HSP 1 Score: 206.838 bits (525), Expect = 2.897e-58 Identity = 97/192 (50.52%), Postives = 127/192 (66.15%), Query Frame = 2
Query: 545 IVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVI 1120
I G +K WY SP+P E + +FICEFC Y +S +Q H +KC LR PPG EIYRK +S FE+DGR K+Y Q LCL++++FL+ KT++YDT+PF FYI+ D+ G H GYFSKEK D NN++CI+TLP YQ G G+ LI+ SY LS+ E G PE+PLS+LG +Y YW TI +
Sbjct: 216 IHFGAFIMKTWYGSPFPAEFINVKKLFICEFCFFYARSDEIMQNHAKKCMLRAPPGLEIYRKGDISVFEVDGRLQKEYCQTLCLVSRMFLESKTVFYDTEPFFFYIVTINDDIGCHFAGYFSKEKYEPDVNNLSCIMTLPCYQEMGLGRFLIDISYALSRKEKWFGGPEQPLSELGRKAYGGYWRTTIASCL 407
BLAST of Histone acetyltransferase vs. Ensembl Celegans
Match: lsy-12 (Histone acetyltransferase [Source:UniProtKB/TrEMBL;Acc:L8E6K3]) HSP 1 Score: 206.838 bits (525), Expect = 2.897e-58 Identity = 97/192 (50.52%), Postives = 127/192 (66.15%), Query Frame = 2
Query: 545 IVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVI 1120
I G +K WY SP+P E + +FICEFC Y +S +Q H +KC LR PPG EIYRK +S FE+DGR K+Y Q LCL++++FL+ KT++YDT+PF FYI+ D+ G H GYFSKEK D NN++CI+TLP YQ G G+ LI+ SY LS+ E G PE+PLS+LG +Y YW TI +
Sbjct: 216 IHFGAFIMKTWYGSPFPAEFINVKKLFICEFCFFYARSDEIMQNHAKKCMLRAPPGLEIYRKGDISVFEVDGRLQKEYCQTLCLVSRMFLESKTVFYDTEPFFFYIVTINDDIGCHFAGYFSKEKYEPDVNNLSCIMTLPCYQEMGLGRFLIDISYALSRKEKWFGGPEQPLSELGRKAYGGYWRTTIASCL 407
BLAST of Histone acetyltransferase vs. Ensembl Fly
Match: Tip60 (gene:FBgn0026080 transcript:FBtr0070668) HSP 1 Score: 419.083 bits (1076), Expect = 2.220e-138 Identity = 206/335 (61.49%), Postives = 252/335 (75.22%), Query Frame = 2
Query: 470 QTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGR 1474
Q+GSM+ +HQ+ D+VTRM+N++MI LG+ RIKPWYFSPYP+EL ++ I+ICEFCLKY KS CL+RHL KC LRHPPGNEIYRK+ +SFFEIDGRKNK YAQNLCLLAKLFLDHKTLYYDTDPFLFY++ E+D GFHIVGYFSKEKES +D NVACILT+PPYQRKGYGKLLIEFSYELSK E KTGSPEKPLSDLGLLSYRSYW QTI+E+ I PS + KP T+ +D+ E TSI +D+ +TL +N+I Y KGQ+++ + + ++++ + +M KRK RID+K L+W PKDWSKR +
Sbjct: 242 QSGSMV--THQD--DVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQN----------------PSTDGE------KPTITI---------NDICECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDKRKIRIDSKCLHWTPKDWSKRSK 541 HSP 2 Score: 57.3806 bits (137), Expect = 3.784e-8 Identity = 25/66 (37.88%), Postives = 45/66 (68.18%), Query Frame = 2
Query: 32 LCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTK 229
L EG +LPV++ +D + AEI+ +E G +++YVH+ ++NKRLD+WV+E+ + ++ FP +
Sbjct: 23 LTEGCRLPVRMHKTDDWPLAEIVSIKELD--GRRQFYVHYVDFNKRLDEWVNEEDLYTRKVQFPRR 86
BLAST of Histone acetyltransferase vs. Ensembl Fly
Match: Tip60 (gene:FBgn0026080 transcript:FBtr0333186) HSP 1 Score: 419.083 bits (1076), Expect = 2.220e-138 Identity = 206/335 (61.49%), Postives = 252/335 (75.22%), Query Frame = 2
Query: 470 QTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGR 1474
Q+GSM+ +HQ+ D+VTRM+N++MI LG+ RIKPWYFSPYP+EL ++ I+ICEFCLKY KS CL+RHL KC LRHPPGNEIYRK+ +SFFEIDGRKNK YAQNLCLLAKLFLDHKTLYYDTDPFLFY++ E+D GFHIVGYFSKEKES +D NVACILT+PPYQRKGYGKLLIEFSYELSK E KTGSPEKPLSDLGLLSYRSYW QTI+E+ I PS + KP T+ +D+ E TSI +D+ +TL +N+I Y KGQ+++ + + ++++ + +M KRK RID+K L+W PKDWSKR +
Sbjct: 242 QSGSMV--THQD--DVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQN----------------PSTDGE------KPTITI---------NDICECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDKRKIRIDSKCLHWTPKDWSKRSK 541 HSP 2 Score: 57.3806 bits (137), Expect = 3.784e-8 Identity = 25/66 (37.88%), Postives = 45/66 (68.18%), Query Frame = 2
Query: 32 LCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTK 229
L EG +LPV++ +D + AEI+ +E G +++YVH+ ++NKRLD+WV+E+ + ++ FP +
Sbjct: 23 LTEGCRLPVRMHKTDDWPLAEIVSIKELD--GRRQFYVHYVDFNKRLDEWVNEEDLYTRKVQFPRR 86
BLAST of Histone acetyltransferase vs. Ensembl Fly
Match: Tip60 (gene:FBgn0026080 transcript:FBtr0333185) HSP 1 Score: 368.237 bits (944), Expect = 1.424e-119 Identity = 170/218 (77.98%), Postives = 193/218 (88.53%), Query Frame = 2
Query: 470 QTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVII 1123
Q+GSM+ +HQ+ D+VTRM+N++MI LG+ RIKPWYFSPYP+EL ++ I+ICEFCLKY KS CL+RHL KC LRHPPGNEIYRK+ +SFFEIDGRKNK YAQNLCLLAKLFLDHKTLYYDTDPFLFY++ E+D GFHIVGYFSKEKES +D NVACILT+PPYQRKGYGKLLIEFSYELSK E KTGSPEKPLSDLGLLSYRSYW QTI+E+ I
Sbjct: 242 QSGSMV--THQD--DVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFI 455 HSP 2 Score: 57.7658 bits (138), Expect = 2.576e-8 Identity = 25/66 (37.88%), Postives = 45/66 (68.18%), Query Frame = 2
Query: 32 LCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTK 229
L EG +LPV++ +D + AEI+ +E G +++YVH+ ++NKRLD+WV+E+ + ++ FP +
Sbjct: 23 LTEGCRLPVRMHKTDDWPLAEIVSIKELD--GRRQFYVHYVDFNKRLDEWVNEEDLYTRKVQFPRR 86
BLAST of Histone acetyltransferase vs. Ensembl Fly
Match: mof (gene:FBgn0014340 transcript:FBtr0070829) HSP 1 Score: 288.886 bits (738), Expect = 1.572e-85 Identity = 177/472 (37.50%), Postives = 254/472 (53.81%), Query Frame = 2
Query: 65 KDSDIYHFAEILKARENKRLGTK-EYYVHFDEYNKRLDDWVSEDRMKMHE------MVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKML-DKFKASMAKR-KYRIDAKLLNWHPK 1453
++ H ++L++R + EYYVH+ N+RLD WV R+ + V P + D + S L + + E + A Y L+ +S ++ +M+ + +++Q+ A + ++ +EH+ I T+++ ID + G I WYFSP+PEE + +++CE+CLKY + HL +C R PPG EIYRK +S +E++G++ Y Q LCL+AKLFLDHK LY+D DPFLFYILCE D+EG HIVGYFSKEK+S ++ NVACIL LPP+QRKG+GKLLI FSYELS+ E GSPEKPLSDLG LSYRSYW T++E++ + P I++K ++ E + I D+ TL +M +I Y KGQ+VI VT K + D + K+ K ID L W P+
Sbjct: 387 REDGTVHRGQVLQSRTTENAAAPDEYYVHYVGLNRRLDGWVGRHRISDNADDLGGITVLPAPPLAPDQPSTSREMLAQQAAAAAAASSERQKRAANKDYY---LSYCENSRYDYSDRKMTRYQKRRYDEINHVQKSHAELTATQAAL----EKEHESI-TKIKYIDKLQFGNYEIDTWYFSPFPEEYGKARTLYVCEYCLKYMRFRSSYAYHLHECDRRRPPGREIYRKGNISIYEVNGKEESLYCQLLCLMAKLFLDHKVLYFDMDPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQRKGFGKLLIAFSYELSRKEGVIGSPEKPLSDLGRLSYRSYWAYTLLELM--------------KTRCAPEQITIK----------------------ELSEMSGITHDDIIYTLQSMKMIKYWKGQNVICVTSKTIQDHLQLPQFKQPKLTIDTDYLVWSPQ 814
BLAST of Histone acetyltransferase vs. Ensembl Fly
Match: chm (gene:FBgn0028387 transcript:FBtr0079443) HSP 1 Score: 276.174 bits (705), Expect = 5.954e-81 Identity = 140/313 (44.73%), Postives = 200/313 (63.90%), Query Frame = 2
Query: 530 RNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKE----KESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKY--RIDAKLLNWHP 1450
+ I I +GK ++K WY SPYP++ L ++ICEFCL+Y KS ++RH EKC RHPPG+EIYRK L +++DG++ K+Y Q+LCLLAK FLDHKTLYYD +PFLFYI+ D +G HIVGYFSK +E N NV+CILTLPPYQRKGYG+LLI+FSY L+++E K GSPEKPLSDLGL+SYRSYW +++ + + + + +I++K DV ++T+I D+ +TL + ++ Y KG+H+++ + +LD+++ + +R +ID L W P
Sbjct: 526 KGIKYISMGKYKMKVWYQSPYPDDAARLPKMYICEFCLRYQKSETGIKRHAEKCVWRHPPGDEIYRKGKLQVWQVDGKRYKQYCQHLCLLAKFFLDHKTLYYDVEPFLFYIMTLADVDGCHIVGYFSKHIPFLQEKNSFYNVSCILTLPPYQRKGYGRLLIDFSYLLTRVEGKIGSPEKPLSDLGLISYRSYWKDVLLDYLCNRSGN---------------TIAIK----------------------DVSQETAIYSYDIVSTLQALGMMKYWKGKHIVLKKQDVLDEYEERVKRRGTFPKIDDSCLRWQP 801
BLAST of Histone acetyltransferase vs. Ensembl Zebrafish
Match: kat5a (K(lysine) acetyltransferase 5a [Source:ZFIN;Acc:ZDB-GENE-040718-57]) HSP 1 Score: 421.009 bits (1081), Expect = 3.421e-139 Identity = 244/549 (44.44%), Postives = 324/549 (59.02%), Query Frame = 2
Query: 29 KLCEGVKLPV---KLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKI----------------HKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSST---SSSALKNEDQMSLVTMDDRNCFSYL----QEPVANVLPQTGSMMVTSH--------------------QEHQDIV---TRM-------RNIDMIV----------LGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV ++ D + AEIL ++ G K YYVH+ ++NKRLD+WV+ DR+ + ++ FP K+ +D + + S + S ++AE+V ++ ++T S A Q +L T F+ EP+ + L G+ + H Q+ D + RM R+ D IV LG+ R+KPWYFSPYP+ELT L I++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D LK E +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ +++ + +M KR RID K L++ PKDWSKRG+W
Sbjct: 7 EITEGCRLPVLRRNQENEDEWPLAEILSVKDIS--GRKLYYVHYVDFNKRLDEWVTPDRLDIKKLQFPKKEAKTPMKNGLSGSRPSSPERDVKKSLDLHVQSASAPSRGKTVPTPKRKAESVSLATQVTAATPVPSLPASTEASQAALYTAIRDASFNIKSREEHEPLTS-LTTNGTTSIQRHLIPPQPGRKRKNCGGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIGCIELGRHRLKPWYFSPYPQELTSLPIIYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKAYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDPKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMD----------------------LKSE-NGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHECAMQKRHLRIDPKCLHFTPKDWSKRGKW 520
BLAST of Histone acetyltransferase vs. Ensembl Zebrafish
Match: kat5a (K(lysine) acetyltransferase 5a [Source:ZFIN;Acc:ZDB-GENE-040718-57]) HSP 1 Score: 417.542 bits (1072), Expect = 1.271e-137 Identity = 204/335 (60.90%), Postives = 250/335 (74.63%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DIVTRM+NI I LG+ R+KPWYFSPYP+ELT L I++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D LK E +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ +++ + +M KR RID K L++ PKDWSKRG+W
Sbjct: 241 TGSLV--SDRSHDDIVTRMKNIGCIELGRHRLKPWYFSPYPQELTSLPIIYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKAYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDPKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMD----------------------LKSE-NGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHECAMQKRHLRIDPKCLHFTPKDWSKRGKW 541 HSP 2 Score: 56.225 bits (134), Expect = 1.223e-7 Identity = 28/71 (39.44%), Postives = 46/71 (64.79%), Query Frame = 2
Query: 29 KLCEGVKLPV---KLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
++ EG +LPV ++ D + AEIL ++ G K YYVH+ ++NKRLD+WV+ DR+ + ++ FP K+
Sbjct: 7 EITEGCRLPVLRRNQENEDEWPLAEILSVKDIS--GRKLYYVHYVDFNKRLDEWVTPDRLDIKKLQFPKKE 75
BLAST of Histone acetyltransferase vs. Ensembl Zebrafish
Match: kat5b (K(lysine) acetyltransferase 5b [Source:ZFIN;Acc:ZDB-GENE-030131-985]) HSP 1 Score: 416.387 bits (1069), Expect = 3.314e-137 Identity = 201/335 (60.00%), Postives = 252/335 (75.22%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DI+TRM+NID I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++++ LK E +P T+ +++ E TS+ +D+ +TL +N+I Y KGQ+++ +++ +++ + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 238 TGSLV--SDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKMYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMN----------------------LKSE-NGERPQMTI---------NEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHERAMHKRHLRIDSKCLHFTPKDWSKRGKW 538 HSP 2 Score: 56.9954 bits (136), Expect = 6.000e-8 Identity = 29/71 (40.85%), Postives = 46/71 (64.79%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDS---DIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
++ EG +LPV K+ D + AEIL ++ G K YYVH+ ++NKRLD+WV+ DR+ + ++ FP K+
Sbjct: 7 EIVEGCRLPVLRKNQENEDEWPLAEILSVKDIP--GRKLYYVHYIDFNKRLDEWVTPDRLDLKKLQFPKKE 75
BLAST of Histone acetyltransferase vs. Ensembl Zebrafish
Match: kat8 (K(lysine) acetyltransferase 8 [Source:ZFIN;Acc:ZDB-GENE-030131-7510]) HSP 1 Score: 335.495 bits (859), Expect = 1.650e-106 Identity = 186/460 (40.43%), Postives = 264/460 (57.39%), Query Frame = 2
Query: 80 YHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQE-AENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRK--YRIDAKLLNWHP 1450
+H AE++++R N++ G +E+YVH+ +N+RLD+WV + R+ + + V D E E + E KI N + D+++ ++Q+ A + P T ++ +EH+ I T+++ +D I +G I WYFSP+PE+ + ++ICE+CLKY K + HL +C+ R PPG EIYRKN +S +E+DG+ +K Y QNLCLLAKLFLDHKTLY+D +PF+FYIL E +++G HIVGYFSKEKES D NNVACILTLPPYQR+GYGK LI FSYELSKLE+ GSPEKPLSDLG LSYRSYW ++E++ D ++S+K D+ + TSI D+ +TL ++N++ Y KGQHVI VT K++++ S +K +D L W P
Sbjct: 113 WHSAEVIQSRLNEQEGREEFYVHYVGFNRRLDEWVGKARLALTKTV---------------------KDAVRKSVEEGGGGELVDQPERKITRNQK------RKHDEIN-----------HVQKTYAEMDPTTAAL----EKEHEAI-TKVKYVDKIQIGNFEIDAWYFSPFPEDYGKQPKLWICEYCLKYMKYEKTFRYHLSQCQWRQPPGKEIYRKNNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFIFYILTEVNKQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG----------------TLSIK----------------------DLSQMTSITQSDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDTHCLKWAP 491
BLAST of Histone acetyltransferase vs. Ensembl Zebrafish
Match: kat8 (K(lysine) acetyltransferase 8 [Source:ZFIN;Acc:ZDB-GENE-030131-7510]) HSP 1 Score: 335.495 bits (859), Expect = 1.650e-106 Identity = 186/460 (40.43%), Postives = 264/460 (57.39%), Query Frame = 2
Query: 80 YHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQE-AENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRK--YRIDAKLLNWHP 1450
+H AE++++R N++ G +E+YVH+ +N+RLD+WV + R+ + + V D E E + E KI N + D+++ ++Q+ A + P T ++ +EH+ I T+++ +D I +G I WYFSP+PE+ + ++ICE+CLKY K + HL +C+ R PPG EIYRKN +S +E+DG+ +K Y QNLCLLAKLFLDHKTLY+D +PF+FYIL E +++G HIVGYFSKEKES D NNVACILTLPPYQR+GYGK LI FSYELSKLE+ GSPEKPLSDLG LSYRSYW ++E++ D ++S+K D+ + TSI D+ +TL ++N++ Y KGQHVI VT K++++ S +K +D L W P
Sbjct: 113 WHSAEVIQSRLNEQEGREEFYVHYVGFNRRLDEWVGKARLALTKTV---------------------KDAVRKSVEEGGGGELVDQPERKITRNQK------RKHDEIN-----------HVQKTYAEMDPTTAAL----EKEHEAI-TKVKYVDKIQIGNFEIDAWYFSPFPEDYGKQPKLWICEYCLKYMKYEKTFRYHLSQCQWRQPPGKEIYRKNNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFIFYILTEVNKQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG----------------TLSIK----------------------DLSQMTSITQSDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDTHCLKWAP 491
BLAST of Histone acetyltransferase vs. Ensembl Xenopus
Match: cxcl12 (C-X-C motif chemokine ligand 12 [Source:Xenbase;Acc:XB-GENE-919853]) HSP 1 Score: 449.899 bits (1156), Expect = 3.667e-151 Identity = 243/494 (49.19%), Postives = 324/494 (65.59%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDR--NCFSYLQEP------VANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV K+ D + AEIL +E G K +YVH+ ++NKRLD+WV+ DR+ + ++ FP K+ + T +SP E + A + L+ + A++ ++ R NC S ++ + + TGS++ S + H DI+TRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFYI+ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++++ LK E T +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ +++ + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 7 EIVEGCRLPVLRKNQDNEVEWPLAEILSIKE--LTGKKLFYVHYIDFNKRLDEWVTHDRLDLKKIQFPKKE------AKTPTKNGLPGSRPSSPEREVVSAWALKETGHVNLSCRDDNGAVRRPSAPAVQPGRKRKSNCLSADEDSQDSSDGIPSAPRMTGSLV--SDRSHDDIITRMKNIECIELGRHRLKPWYFSPYPQELTVLPVLYLCEFCLKYVKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYIMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILME----------------------LKTE-TGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHEKAMQKRVLRIDSKCLHFTPKDWSKRGKW 458
BLAST of Histone acetyltransferase vs. Ensembl Xenopus
Match: cxcl12 (C-X-C motif chemokine ligand 12 [Source:Xenbase;Acc:XB-GENE-919853]) HSP 1 Score: 447.588 bits (1150), Expect = 3.374e-150 Identity = 245/498 (49.20%), Postives = 326/498 (65.46%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANA----QEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDR--NCFSYLQEP------VANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV K+ D + AEIL +E G K +YVH+ ++NKRLD+WV+ DR+ + ++ FP K+ + T +SP E + +E +V R + +S L+ ++ R NC S ++ + + TGS++ S + H DI+TRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFYI+ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++++ LK E T +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ +++ + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 7 EIVEGCRLPVLRKNQDNEVEWPLAEILSIKE--LTGKKLFYVHYIDFNKRLDEWVTHDRLDLKKIQFPKKE------AKTPTKNGLPGSRPSSPEREVVSAWALKETGHVNLSCRDDVDHNSYPLRRPSAPAVQPGRKRKSNCLSADEDSQDSSDGIPSAPRMTGSLV--SDRSHDDIITRMKNIECIELGRHRLKPWYFSPYPQELTVLPVLYLCEFCLKYVKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYIMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILME----------------------LKTE-TGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHEKAMQKRVLRIDSKCLHFTPKDWSKRGKW 462
BLAST of Histone acetyltransferase vs. Ensembl Xenopus
Match: cxcl12 (C-X-C motif chemokine ligand 12 [Source:Xenbase;Acc:XB-GENE-919853]) HSP 1 Score: 444.891 bits (1143), Expect = 5.010e-149 Identity = 245/506 (48.42%), Postives = 325/506 (64.23%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANA----QEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDR--NCFSY------------LQEPVANVLPQTGSMM--VTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV K+ D + AEIL +E G K +YVH+ ++NKRLD+WV+ DR+ + ++ FP K+ + T +SP E + +E +V R + +S L+ ++ R NC S+ L ++ +P M + S + H DI+TRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFYI+ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++++ LK E T +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ +++ + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 5 EIVEGCRLPVLRKNQDNEVEWPLAEILSIKE--LTGKKLFYVHYIDFNKRLDEWVTHDRLDLKKIQFPKKE------AKTPTKNGLPGSRPSSPEREVVSAWALKETGHVNLSCRDDVDHNSYPLRRPSAPAVQPGRKRKSNCLSFTDRCLDIFLYNSLYNDSSDGIPSAPRMTGSLVSDRSHDDIITRMKNIECIELGRHRLKPWYFSPYPQELTVLPVLYLCEFCLKYVKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYIMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILME----------------------LKTE-TGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHEKAMQKRVLRIDSKCLHFTPKDWSKRGKW 470
BLAST of Histone acetyltransferase vs. Ensembl Xenopus
Match: cxcl12 (C-X-C motif chemokine ligand 12 [Source:Xenbase;Acc:XB-GENE-919853]) HSP 1 Score: 443.736 bits (1140), Expect = 1.209e-148 Identity = 246/520 (47.31%), Postives = 322/520 (61.92%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPV----------ANVLPQ------------------------TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV K+ D + AEIL +E G K +YVH+ ++NKRLD+WV+ DR+ + ++ FP K+ + + P ++ E E V S+ ALK ++L DD+ + V PQ TGS++ S + H DI+TRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFYI+ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++++ LK E T +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ +++ + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 6 EIVEGCRLPVLRKNQDNEVEWPLAEILSIKE--LTGKKLFYVHYIDFNKRLDEWVTHDRLDLKKIQFPKKEAKTPTK-------------NGLPGSRPSSPEREVV----------SAWALKETGHVNLSCRDDKRKVDIVSPATPVPPPPETTQVTVFPQVKLLIQTYFDSQDSSDGIPSAPRMTGSLV--SDRSHDDIITRMKNIECIELGRHRLKPWYFSPYPQELTVLPVLYLCEFCLKYVKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYIMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILME----------------------LKTE-TGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHEKAMQKRVLRIDSKCLHFTPKDWSKRGKW 466
BLAST of Histone acetyltransferase vs. Ensembl Xenopus
Match: cxcl12 (C-X-C motif chemokine ligand 12 [Source:Xenbase;Acc:XB-GENE-919853]) HSP 1 Score: 413.69 bits (1062), Expect = 1.993e-136 Identity = 203/335 (60.60%), Postives = 253/335 (75.52%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DI+TRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFYI+ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++++ LK E T +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ +++ + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 204 TGSLV--SDRSHDDIITRMKNIECIELGRHRLKPWYFSPYPQELTVLPVLYLCEFCLKYVKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYIMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILME----------------------LKTE-TGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHEKAMQKRVLRIDSKCLHFTPKDWSKRGKW 504 HSP 2 Score: 57.7658 bits (138), Expect = 5.564e-8 Identity = 30/74 (40.54%), Postives = 47/74 (63.51%), Query Frame = 2
Query: 20 MFNKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
M ++ EG +LPV K+ D + AEIL +E G K +YVH+ ++NKRLD+WV+ DR+ + ++ FP K+
Sbjct: 1 MAAEIVEGCRLPVLRKNQDNEVEWPLAEILSIKE--LTGKKLFYVHYIDFNKRLDEWVTHDRLDLKKIQFPKKE 72
BLAST of Histone acetyltransferase vs. Ensembl Mouse
Match: Kat5 (K(lysine) acetyltransferase 5 [Source:MGI Symbol;Acc:MGI:1932051]) HSP 1 Score: 443.351 bits (1139), Expect = 2.509e-148 Identity = 239/500 (47.80%), Postives = 324/500 (64.80%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSAL---KNEDQMSLVTMDDR----NCFSYLQEP------VANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+ + T SP E ++ E V + S T+ +++ + ++ R NC ++ + + TGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 38 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKE------AKTPTKNGLPGSRPGSPEREVK-RKVEVVSPATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLV--SDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 494
BLAST of Histone acetyltransferase vs. Ensembl Mouse
Match: Kat5 (K(lysine) acetyltransferase 5 [Source:MGI Symbol;Acc:MGI:1932051]) HSP 1 Score: 442.195 bits (1136), Expect = 2.951e-148 Identity = 239/500 (47.80%), Postives = 324/500 (64.80%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSAL---KNEDQMSLVTMDDR----NCFSYLQEP------VANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+ + T SP E ++ E V + S T+ +++ + ++ R NC ++ + + TGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKE------AKTPTKNGLPGSRPGSPEREVK-RKVEVVSPATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLV--SDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 461
BLAST of Histone acetyltransferase vs. Ensembl Mouse
Match: Kat5 (K(lysine) acetyltransferase 5 [Source:MGI Symbol;Acc:MGI:1932051]) HSP 1 Score: 412.92 bits (1060), Expect = 4.010e-136 Identity = 237/543 (43.65%), Postives = 324/543 (59.67%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAE-NVEYKIRLNSSTSSSALKNED------QMSLVTMDDRNCFSYLQ-----EPV------ANVLPQTGSMM---------------VTSHQEHQD------IVTRM-------RNIDMIV----------LGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+ + + + + +A+ + V+ +R N A+ + S + + R+ ++ PV A+V PQ GS + + ++ QD RM R+ D IV LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 513
BLAST of Histone acetyltransferase vs. Ensembl Mouse
Match: Kat8 (K(lysine) acetyltransferase 8 [Source:MGI Symbol;Acc:MGI:1915023]) HSP 1 Score: 330.872 bits (847), Expect = 3.140e-105 Identity = 185/459 (40.31%), Postives = 265/459 (57.73%), Query Frame = 2
Query: 80 YHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKF--KASMAKRKYRIDAKLLNWHP 1450
+H AE++++R N + G +E+YVH+ +N+RLD+WV ++R+ + + V D + ++ AE E KI N + D+++ ++Q+ A + P T ++ +EH+ I T+++ +D I +G I WYFSP+PE+ + +++CE+CLKY K + HL +C+ R PPG EIYRK+ +S +E+DG+ +K Y QNLCLLAKLFLDHKTLY+D +PF+FYIL E D +G HIVGYFSKEKES D NNVACILTLPPYQR+GYGK LI FSYELSKLE+ GSPEKPLSDLG LSYRSYW ++E++ D ++S+K D+ + TSI D+ +TL ++N++ Y KGQHVI VT K++++ A K +D+ L W P
Sbjct: 70 WHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTV---------------------KDAVQKNSEKYLSELAEQPERKITRNQK------RKHDEIN-----------HVQKTYAEMDPTTAAL----EKEHEAI-TKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKFEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG----------------TLSIK----------------------DLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAP 447
BLAST of Histone acetyltransferase vs. Ensembl Mouse
Match: Kat5 (K(lysine) acetyltransferase 5 [Source:MGI Symbol;Acc:MGI:1932051]) HSP 1 Score: 297.36 bits (760), Expect = 5.234e-92 Identity = 171/387 (44.19%), Postives = 227/387 (58.66%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSDI---YHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAE-NVEYKIRLNSSTSSSALKNED------QMSLVTMDDRNCFSYLQ-----EPV------ANVLPQTGSMM---------------VTSHQEHQD------IVTRM-------RNIDMIV----------LGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFS 1009
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+ + + + + +A+ + V+ +R N A+ + S + + R+ ++ PV A+V PQ GS + + ++ QD RM R+ D IV LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFS
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFS 389
BLAST of Histone acetyltransferase vs. UniProt/SwissProt
Match: sp|Q5RBG4|KAT5_PONAB (Histone acetyltransferase KAT5 OS=Pongo abelii OX=9601 GN=KAT5 PE=2 SV=1) HSP 1 Score: 441.81 bits (1135), Expect = 2.534e-147 Identity = 239/500 (47.80%), Postives = 324/500 (64.80%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSAL---KNEDQMSLVTMDDR----NCFSYLQEP------VANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+ + T SP E ++ E V + S T+ +++ + ++ R NC ++ + + TGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKE------AKTPTKNGLPGSRPGSPEREVK-RKVEVVSPATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLV--SDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 461
BLAST of Histone acetyltransferase vs. UniProt/SwissProt
Match: sp|Q960X4|TIP60_DROME (Histone acetyltransferase Tip60 OS=Drosophila melanogaster OX=7227 GN=Tip60 PE=1 SV=1) HSP 1 Score: 419.083 bits (1076), Expect = 2.225e-137 Identity = 206/335 (61.49%), Postives = 252/335 (75.22%), Query Frame = 2
Query: 470 QTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGR 1474
Q+GSM+ +HQ+ D+VTRM+N++MI LG+ RIKPWYFSPYP+EL ++ I+ICEFCLKY KS CL+RHL KC LRHPPGNEIYRK+ +SFFEIDGRKNK YAQNLCLLAKLFLDHKTLYYDTDPFLFY++ E+D GFHIVGYFSKEKES +D NVACILT+PPYQRKGYGKLLIEFSYELSK E KTGSPEKPLSDLGLLSYRSYW QTI+E+ I PS + KP T+ +D+ E TSI +D+ +TL +N+I Y KGQ+++ + + ++++ + +M KRK RID+K L+W PKDWSKR +
Sbjct: 242 QSGSMV--THQD--DVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQN----------------PSTDGE------KPTITI---------NDICECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDKRKIRIDSKCLHWTPKDWSKRSK 541 HSP 2 Score: 57.3806 bits (137), Expect = 3.793e-7 Identity = 25/66 (37.88%), Postives = 45/66 (68.18%), Query Frame = 2
Query: 32 LCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTK 229
L EG +LPV++ +D + AEI+ +E G +++YVH+ ++NKRLD+WV+E+ + ++ FP +
Sbjct: 23 LTEGCRLPVRMHKTDDWPLAEIVSIKELD--GRRQFYVHYVDFNKRLDEWVNEEDLYTRKVQFPRR 86
BLAST of Histone acetyltransferase vs. UniProt/SwissProt
Match: sp|Q99MK2|KAT5_RAT (Histone acetyltransferase KAT5 OS=Rattus norvegicus OX=10116 GN=Kat5 PE=1 SV=2) HSP 1 Score: 412.92 bits (1060), Expect = 2.805e-135 Identity = 237/543 (43.65%), Postives = 324/543 (59.67%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAE-NVEYKIRLNSSTSSSALKNED------QMSLVTMDDRNCFSYLQ-----EPV------ANVLPQTGSMM---------------VTSHQEHQD------IVTRM-------RNIDMIV----------LGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+ + + + + +A+ + V+ +R N A+ + S + + R+ ++ PV A+V PQ GS + + ++ QD RM R+ D IV LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 513
BLAST of Histone acetyltransferase vs. UniProt/SwissProt
Match: sp|Q8CHK4|KAT5_MOUSE (Histone acetyltransferase KAT5 OS=Mus musculus OX=10090 GN=Kat5 PE=1 SV=2) HSP 1 Score: 412.92 bits (1060), Expect = 2.805e-135 Identity = 237/543 (43.65%), Postives = 324/543 (59.67%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAE-NVEYKIRLNSSTSSSALKNED------QMSLVTMDDRNCFSYLQ-----EPV------ANVLPQTGSMM---------------VTSHQEHQD------IVTRM-------RNIDMIV----------LGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+ + + + + +A+ + V+ +R N A+ + S + + R+ ++ PV A+V PQ GS + + ++ QD RM R+ D IV LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 513
BLAST of Histone acetyltransferase vs. UniProt/SwissProt
Match: sp|Q92993|KAT5_HUMAN (Histone acetyltransferase KAT5 OS=Homo sapiens OX=9606 GN=KAT5 PE=1 SV=2) HSP 1 Score: 412.535 bits (1059), Expect = 3.831e-135 Identity = 202/335 (60.30%), Postives = 252/335 (75.22%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY +S CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ + LK E + +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID+K L++ PKDWSKRG+W
Sbjct: 213 TGSLV--SDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEIL----------------------MGLKSE-SGERPQITI---------NEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW 513 HSP 2 Score: 53.1434 bits (126), Expect = 7.194e-6 Identity = 26/72 (36.11%), Postives = 46/72 (63.89%), Query Frame = 2
Query: 26 NKLCEGVKLPVKLKDSD---IYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
++ EG +LPV ++ D + AEIL ++ G K +YVH+ ++NKRLD+WV+ +R+ + ++ FP K+
Sbjct: 5 GEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDIS--GRKLFYVHYIDFNKRLDEWVTHERLDLKKIQFPKKE 74
BLAST of Histone acetyltransferase vs. TrEMBL
Match: A0A517D2D1 (Histone acetyltransferase OS=Dugesia japonica OX=6161 GN=Tip60 PE=2 SV=1) HSP 1 Score: 788.489 bits (2035), Expect = 0.000e+0 Identity = 409/497 (82.29%), Postives = 443/497 (89.13%), Query Frame = 2
Query: 17 IMFNKLCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXX----------XXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
+M+NKL EGVKLPVKLKDSD+YH AEILKARENK+LGTKEYYVHFDEYNKRLDDWVSEDRMK++EM+FP+KKIHKDSSTASL+A + N+CSNSPFGE QE+E+VE K+RL +S+SSSALKNE+Q+SLV+MDDRNCFSYLQEPV+NVLPQTGSMMV SHQEHQDIVTRMRNID+IVLGK RIKPWYFSPYPEELTELD+++ICEFCLKYFK+C CLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYD+ GFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVII A +++ +NSSS +FDPPSISL +D+VEKTSINPKDL ATLNTMNIIYYSKGQHVIVVTKKMLD FKASM+KRKYRIDAKLLNWHPKDWSKRGRW
Sbjct: 1 MMYNKLYEGVKLPVKLKDSDVYHLAEILKARENKKLGTKEYYVHFDEYNKRLDDWVSEDRMKINEMIFPSKKIHKDSSTASLSALGGSSGNNNSSNNNNECSNSPFGETVNQESEHVELKMRLTTSSSSSALKNEEQISLVSMDDRNCFSYLQEPVSNVLPQTGSMMVASHQEHQDIVTRMRNIDLIVLGKYRIKPWYFSPYPEELTELDSVYICEFCLKYFKTCLCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDDRGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVII-DAANSNDNSNSSSLSFDPPSISL----------------------NDIVEKTSINPKDLTATLNTMNIIYYSKGQHVIVVTKKMLDNFKASMSKRKYRIDAKLLNWHPKDWSKRGRW 474
BLAST of Histone acetyltransferase vs. TrEMBL
Match: A0A0X3PW26 (Histone acetyltransferase (Fragment) OS=Schistocephalus solidus OX=70667 GN=KAT5 PE=3 SV=1) HSP 1 Score: 491.115 bits (1263), Expect = 1.306e-163 Identity = 253/483 (52.38%), Postives = 332/483 (68.74%), Query Frame = 2
Query: 38 EGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNE---DQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
EG K+PV+L+ S +H AEIL RE + YYVHFD++NKRLD+WV E R+ + +P K++ ++SS+ +LT++ + + P E E + R++SS++ S+LK + D+ S ++ + + +P LP+ MV+SH E QD+VTR+RN++ I +G+ RIKPWYFSPYP EL D ++ICEFCLKY KS CL+RHL KC+LRHPPGNEIYRK P SFFEIDGRKNK YAQ+LCLLAKLFLDHKTLYYDTDPFLFY+LCE D G+HIVGYFSKEKES++D NVACILTLPPYQRKGYGKLLIEFSYELSK+E K GSPEKPLSDLGLLSYRSYW T+M++ + G P+IS+ +++VE+TS+ D+ ATL+ +N++YY KGQ++I ++K+ L+ K +++KR R+D L+W PKDWSKRGRW
Sbjct: 38 EGCKVPVRLRHSRYFHAAEILGVRETE--DGVFYYVHFDDFNKRLDEWVEESRLDFDRIEWPAKRLPRESSSTALTSMATVDSSIKLPISVECGPEPEPNVTRSRMHSSSNLSSLKRKHPSDEDSTSSLQTNDLDDHTDKPKLTTLPRQTGSMVSSHHE-QDVVTRIRNLEWIEIGQYRIKPWYFSPYPVELVSADCVYICEFCLKYLKSRTCLRRHLTKCQLRHPPGNEIYRKIPHSFFEIDGRKNKTYAQHLCLLAKLFLDHKTLYYDTDPFLFYVLCETDSRGYHIVGYFSKEKESSEDYNVACILTLPPYQRKGYGKLLIEFSYELSKIEGKLGSPEKPLSDLGLLSYRSYWAMTLMDIFLSTKPPEPGQE---------PAISI----------------------NEIVERTSMKRDDVIATLSYLNVLYYVKGQYLIFLSKENLELHKRAISKRLVRVDPTCLSWKPKDWSKRGRW 486
BLAST of Histone acetyltransferase vs. TrEMBL
Match: A0A4Z2CM24 (Histone acetyltransferase OS=Schistosoma japonicum OX=6182 GN=EWB00_009345 PE=3 SV=1) HSP 1 Score: 487.649 bits (1254), Expect = 1.314e-162 Identity = 256/489 (52.35%), Postives = 326/489 (66.67%), Query Frame = 2
Query: 38 EGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAE-NVEYKIRLNSSTSSSALKN--------EDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
EG KLPVKL DSD +H AEIL R+ YYVH+D+YNKRLD+WVS DR+ ++ P KK K+ T T + ++ NS E E++ N K R +SS+ + LK E + L +D N F + + P+ MV+SH E QD VTRMRN++ I LG+ RIKPWYFSPYP+EL + ++ICEFCLKY KS CL+RHL KC LR+PPGNE+YRK P SFFEIDGRKNK YAQ+LCLLAKLFLDHKTLYYDTDPFLFY+LCE D G+H+VGYFSKEKES++D NVACIL LPP+QRKGYGK LIEFSYELSK+E K+GSPEKPLSDLGLLSYRSYW QTI+E++++ + G P++S+ +D+V++T I D+ ATL+ +N++YY KGQHVI +++ ++ +M +R R+D+KLLNW +DWSKRGRW
Sbjct: 11 EGCKLPVKLPDSDFFHTAEILGTRDVG--DCTYYYVHYDDYNKRLDEWVSADRLDFSKIERPLKKSTKEPVTPVFTLSSTDDEVVNS--AELRNSESDLNPPIKHRSSSSSCLTQLKRKRPPDDIYEGPIHLTLQNDLNDFVFDDSAASTGKPRQTGSMVSSHHE-QDTVTRMRNLEWIELGRYRIKPWYFSPYPQELATVPCVYICEFCLKYLKSFTCLRRHLAKCTLRNPPGNEVYRKLPHSFFEIDGRKNKTYAQHLCLLAKLFLDHKTLYYDTDPFLFYVLCEIDSRGYHLVGYFSKEKESSEDYNVACILVLPPFQRKGYGKYLIEFSYELSKIEGKSGSPEKPLSDLGLLSYRSYWAQTILELLLNSKAAETGQD---------PALSI----------------------NDIVDRTCIKRDDVIATLSHLNVLYYVKGQHVIYLSRDLIQAHNKAMQRRNLRVDSKLLNWKARDWSKRGRW 463
BLAST of Histone acetyltransferase vs. TrEMBL
Match: Q5DDR3 (Histone acetyltransferase OS=Schistosoma japonicum OX=6182 PE=2 SV=1) HSP 1 Score: 486.878 bits (1252), Expect = 2.599e-162 Identity = 255/488 (52.25%), Postives = 324/488 (66.39%), Query Frame = 2
Query: 38 EGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKN--------EDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
EG KLPVKL DSD +H AEIL R+ YYVH+D+YNKRLD+WVS DR+ ++ P KK K+ T T + ++ NS N+ N K R +SS+ + LK E + L +D N F + + P+ MV+SH E QD VTRMRN++ I LG+ RIKPWYFSPYP+EL + ++ICEFCLKY KS CL+RHL KC LR+PPGNE+YRK P SFFEIDGRKNK YAQ+LCLLAKLFLDHKTLYYDTDPFLFY+LCE D G+H+VGYFSKEKES++D NVACIL LPP+QRKGYGK LIEFSYELSK+E K+GSPEKPLSDLGLLSYRSYW QTI+E++++ + G P++S+ +D+V++T I D+ ATL+ +N++YY KGQHVI +++ ++ +M +R R+D+KLLNW +DWSKRGRW
Sbjct: 11 EGCKLPVKLPDSDFFHTAEILGTRDVG--DCTYYYVHYDDYNKRLDEWVSADRLDFSKIERPLKKSTKEPVTPVFTLSSTDDEVVNSA-ELRNSDSDLNPPIKHRSSSSSCLTQLKRKRPPDDIYEGPIHLTLQNDLNDFVFDDSAASTGKPRQTGSMVSSHHE-QDTVTRMRNLEWIELGRYRIKPWYFSPYPQELATVPCVYICEFCLKYLKSFTCLRRHLAKCTLRNPPGNEVYRKLPHSFFEIDGRKNKTYAQHLCLLAKLFLDHKTLYYDTDPFLFYVLCEIDSRGYHLVGYFSKEKESSEDYNVACILVLPPFQRKGYGKYLIEFSYELSKIEGKSGSPEKPLSDLGLLSYRSYWAQTILELLLNSKAAETGQD---------PALSI----------------------NDIVDRTCIKRDDVIATLSHLNVLYYVKGQHVIYLSRDLIQAHNKAMQRRNLRVDSKLLNWKARDWSKRGRW 463
BLAST of Histone acetyltransferase vs. TrEMBL
Match: G4LXT0 (Histone acetyltransferase OS=Schistosoma mansoni OX=6183 GN=Smp_053140 PE=3 SV=1) HSP 1 Score: 485.337 bits (1248), Expect = 9.738e-162 Identity = 257/489 (52.56%), Postives = 327/489 (66.87%), Query Frame = 2
Query: 38 EGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAE-NVEYKIRLNSSTSSSALKN--------EDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
EG KLPVKL DSD +H AEIL R+ YYVH+D+YNKRLD+WVS DR+ + P KK K+ T + + ++ +S E E++ N K R +SS+S + LK E + L +D N + P + P+ MV+SH E QD VTRMRN++ I LG+ RIKPWYFSPYP+EL + ++ICEFCLKY KS CL+RHL KC LR+PPGNE+YRK P SFFEIDGRKNK YAQ+LCLLAKLFLDHKTLYYDTDPFLFY+LCE D G+H+VGYFSKEKES++D NVACIL LPP+QRKGYGK LIEFSYELSK+E K+GSPEKPLSDLGLLSYRSYW QTI+E++++ + G P++S+ +D+V++T I D+ ATL+ +N++YY KGQHVI +++ ++ + SM +R R+DAKLLNW +DWSKRGRW
Sbjct: 11 EGCKLPVKLPDSDFFHNAEILGTRDVG--DCTYYYVHYDDYNKRLDEWVSADRLDFSRIERPLKKSTKEPVTPVFSLSSTEDEVISS--AELRTSESDLNPPLKYRSSSSSSLTQLKRKRPPDDIYEGPIHLTLQNDLNDLVFDDSPTSAGKPRQTGSMVSSHHE-QDTVTRMRNLEWIELGRYRIKPWYFSPYPQELASVPCVYICEFCLKYLKSFTCLRRHLAKCTLRNPPGNEVYRKLPHSFFEIDGRKNKTYAQHLCLLAKLFLDHKTLYYDTDPFLFYVLCEVDSRGYHLVGYFSKEKESSEDYNVACILVLPPFQRKGYGKYLIEFSYELSKIEGKSGSPEKPLSDLGLLSYRSYWAQTILELLLNSKATETGQD---------PALSI----------------------NDIVDRTCIKRDDVIATLSHLNVLYYVKGQHVIYLSRDLIQAHQKSMQRRNLRVDAKLLNWKSRDWSKRGRW 463
BLAST of Histone acetyltransferase vs. Ensembl Cavefish
Match: kat5b (K(lysine) acetyltransferase 5b [Source:ZFIN;Acc:ZDB-GENE-030131-985]) HSP 1 Score: 441.81 bits (1135), Expect = 8.046e-148 Identity = 237/519 (45.66%), Postives = 323/519 (62.24%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDS---DIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTS-SSALKNEDQMSLVTMDDRNCFSYL------------------------------QEPVANVLPQTGSMM--VTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV K+ D + AEIL ++ LG K +YVH+ ++NKRLD+WV+ DR+ M ++ FP K+ + + S+ + + N Q A L + + A + ++++ ++C + L + ++ +P M + S + H DI+TRM+NID I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D+ + + P I++ +++ E TS+ +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID K L++ PKDWSKRG+W
Sbjct: 2 EIVEGCRLPVLRKNQENEDEWPLAEILSVKDT--LGRKLFYVHYIDFNKRLDEWVTPDRLDMKKLQFPKKEAKTPTKNGLPGSRPSSPEREVRKSLDLNVQAASAPSRGKTLPTPVQLTLAHSTPKKYTILSYHIKSCMNGLTMTCFLKCPNWILSDTFFPHALNSSLWPQDSQDSSDGIPTAPRMTGSLVSDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKTYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMDLKSDNG----------ERPQITI----------------------NEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMQKRHLRIDPKCLHFTPKDWSKRGKW 486
BLAST of Histone acetyltransferase vs. Ensembl Cavefish
Match: kat5b (K(lysine) acetyltransferase 5b [Source:ZFIN;Acc:ZDB-GENE-030131-985]) HSP 1 Score: 423.32 bits (1087), Expect = 2.265e-140 Identity = 240/545 (44.04%), Postives = 327/545 (60.00%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDS---DIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKI----------------HKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTM--DDRNCFSYL---QEPVAN-----------VLP--QTGSMMVT--SHQEHQD------IVTRM-------RNIDMIV----------LGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV K+ D + AEIL ++ LG K +YVH+ ++NKRLD+WV+ DR+ M ++ FP K+ ++ + + + + S ++AE V ++ +TS +L + + + ++ R F+ EP+ + VLP Q G T + ++ QD RM R+ D I+ LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D+ + P I++ +++ E TS+ +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID K L++ PKDWSKRG+W
Sbjct: 2 EIVEGCRLPVLRKNQENEDEWPLAEILSVKDT--LGRKLFYVHYIDFNKRLDEWVTPDRLDMKKLQFPKKEAKTPTKNGLPGSRPSSPEREVRKSLDLNVQAASAPSRGKTLPTPKRKAETVSLASQVTPATSVPSLPSSAEATQASVYPAARETFTTKTREDEPLTSITTVTNGTTRRVLPPSQPGRKRKTCGTDEDSQDSSDGIPTAPRMTGSLVSDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKTYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMDLKSDNGER----------PQITI----------------------NEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMQKRHLRIDPKCLHFTPKDWSKRGKW 512
BLAST of Histone acetyltransferase vs. Ensembl Cavefish
Match: kat5b (K(lysine) acetyltransferase 5b [Source:ZFIN;Acc:ZDB-GENE-030131-985]) HSP 1 Score: 424.091 bits (1089), Expect = 9.174e-140 Identity = 240/550 (43.64%), Postives = 326/550 (59.27%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDS---DIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTM--DDRNCFSYL---QEPVANVL------------------------------------PQTGSMMVTSHQEHQD------IVTRM-------RNIDMIV----------LGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
++ EG +LPV K+ D + AEIL ++ LG K +YVH+ ++NKRLD+WV+ DR+ M ++ FP K+ + T +SP E ++AE V ++ +TS +L + + + ++ R F+ EP+ ++ P+T S + ++ QD RM R+ D I+ LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D+ + + P I++ +++ E TS+ +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID K L++ PKDWSKRG+W
Sbjct: 67 EIVEGCRLPVLRKNQENEDEWPLAEILSVKDT--LGRKLFYVHYIDFNKRLDEWVTPDRLDMKKLQFPKKE------AKTPTKNGLPGSRPSSPEREVK-RKAETVSLASQVTPATSVPSLPSSAEATQASVYPAARETFTTKTREDEPLTSITTVTNGTTRRVLPPSQPGRKRKTCGTDEMIKVFQYNSPRTTSGCLPPGEDSQDSSDGIPTAPRMTGSLVSDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKTYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMDLKSDNG----------ERPQITI----------------------NEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMQKRHLRIDPKCLHFTPKDWSKRGKW 575
BLAST of Histone acetyltransferase vs. Ensembl Cavefish
Match: kat5b (K(lysine) acetyltransferase 5b [Source:ZFIN;Acc:ZDB-GENE-030131-985]) HSP 1 Score: 416.772 bits (1070), Expect = 1.526e-137 Identity = 200/335 (59.70%), Postives = 250/335 (74.63%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DI+TRM+NID I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D+ + P I++ +++ E TS+ +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID K L++ PKDWSKRG+W
Sbjct: 233 TGSLV--SDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKTYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMDLKSDNGER----------PQITI----------------------NEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMQKRHLRIDPKCLHFTPKDWSKRGKW 533 HSP 2 Score: 60.4622 bits (145), Expect = 4.264e-9 Identity = 30/71 (42.25%), Postives = 47/71 (66.20%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDS---DIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
++ EG +LPV K+ D + AEIL ++ LG K +YVH+ ++NKRLD+WV+ DR+ M ++ FP K+
Sbjct: 2 EIVEGCRLPVLRKNQENEDEWPLAEILSVKDT--LGRKLFYVHYIDFNKRLDEWVTPDRLDMKKLQFPKKE 70
BLAST of Histone acetyltransferase vs. Ensembl Cavefish
Match: kat5b (K(lysine) acetyltransferase 5b [Source:ZFIN;Acc:ZDB-GENE-030131-985]) HSP 1 Score: 418.313 bits (1074), Expect = 3.915e-137 Identity = 200/335 (59.70%), Postives = 251/335 (74.93%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DI+TRM+NID I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D+ + + P I++ +++ E TS+ +D+ +TL +N+I Y KGQ+++ +++ ++D + +M KR RID K L++ PKDWSKRG+W
Sbjct: 298 TGSLV--SDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKTYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMDLKSDNG----------ERPQITI----------------------NEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMQKRHLRIDPKCLHFTPKDWSKRGKW 598 HSP 2 Score: 60.4622 bits (145), Expect = 4.293e-9 Identity = 30/71 (42.25%), Postives = 47/71 (66.20%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDS---DIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
++ EG +LPV K+ D + AEIL ++ LG K +YVH+ ++NKRLD+WV+ DR+ M ++ FP K+
Sbjct: 67 EIVEGCRLPVLRKNQENEDEWPLAEILSVKDT--LGRKLFYVHYIDFNKRLDEWVTPDRLDMKKLQFPKKE 135
BLAST of Histone acetyltransferase vs. Ensembl Sea Lamprey
Match: kat5b (K(lysine) acetyltransferase 5b [Source:ZFIN;Acc:ZDB-GENE-030131-985]) HSP 1 Score: 416.387 bits (1069), Expect = 2.005e-138 Identity = 203/343 (59.18%), Postives = 256/343 (74.64%), Query Frame = 2
Query: 449 PVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
P ++ QTGS++ S + H DIVTRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRH+ KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ +D +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYG LLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E++ID LK E +P T+ +++ E TSI +D+ +TL +N+I Y KGQ+++ ++ ++++ + +MAKR+ RID+K L++ PKDWSKRG+W
Sbjct: 198 PAVSLPRQTGSLV--SDKSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTSLPVLYLCEFCLKYLKSLTCLQRHMHKCNLRHPPGNEIYRKGNISFFEIDGRKNKAYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTTFDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGTLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILID----------------------LKAE-NGERPQITI---------NEISELTSIKKEDVISTLQHLNLINYYKGQYILNLSYEIIEGHQKAMAKRELRIDSKCLHFTPKDWSKRGKW 506
BLAST of Histone acetyltransferase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007004.1 (pep scaffold:Pmarinus_7.0:GL480995:3484:21994:1 gene:ENSPMAG00000006332.1 transcript:ENSPMAT00000007004.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 281.952 bits (720), Expect = 7.201e-89 Identity = 137/277 (49.46%), Postives = 181/277 (65.34%), Query Frame = 2
Query: 533 NIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIV 1363
I IV G+ + WY SPYPEE T L +++CEFCLKY KS L+RH+ KC +HPPG+EIYR +S FE+DG+KNK Y QNLCLLAKLFLDHKTLYYD +PFLFY++ E D G H+VGYFSKEK S + NV+CILT+P + R+GYGK+LIEFSY LSK+E+K GSPE+PLSDLGL+SYRSYW ++ + F IS+K ++ ++T+INP D+ +TL + ++ Y KG+H+++
Sbjct: 100 GIRTIVFGRYELDTWYHSPYPEEYTRLGKLYVCEFCLKYMKSPTILRRHMAKCVWKHPPGDEIYRNGTVSVFEVDGKKNKTYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEGDNAGCHLVGYFSKEKNSFLNYNVSCILTMPQFMRQGYGKMLIEFSYLLSKMEDKIGSPERPLSDLGLISYRSYWKGVVLRYL---------------HGFHGKEISIK----------------------EISQETAINPADIVSTLQYLQMLKYWKGKHLVL 339
BLAST of Histone acetyltransferase vs. Ensembl Sea Lamprey
Match: kat7b (K(lysine) acetyltransferase 7b [Source:ZFIN;Acc:ZDB-GENE-030131-1901]) HSP 1 Score: 287.73 bits (735), Expect = 1.625e-88 Identity = 147/312 (47.12%), Postives = 194/312 (62.18%), Query Frame = 2
Query: 536 IDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKF---KASMAKRKYRIDAKLLNWHPKDWS 1462
I I+ G+ + WY SPYPEE L +++CEFCLKY KS L+RH EKC +HPPG+EIYRK +S FE+DG+KNK Y QNLCLLAKLFLDHKTLYYD +PFLFY++ E D G HI+GYFSKEK S + NV+CILT+P + R+GYGK+LI+FSY LSK ENK GSPE+PLSDLGL+SYRSYW + ++ + AF IS+K ++ + T++NP D+ TL + ++ Y KG+H+++ + ++D F +AS ID L W P S
Sbjct: 267 IKSIMFGRYELDTWYHSPYPEEYARLGRLYVCEFCLKYMKSQTILRRHTEKCVWKHPPGDEIYRKGTISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEGDNTGCHIIGYFSKEKNSFLNYNVSCILTMPQFMRQGYGKMLIDFSYLLSKEENKIGSPERPLSDLGLISYRSYWKEVLLRYL---------------HAFQGKEISIK----------------------EISQDTAVNPVDIVNTLQALQMLKYWKGKHLVLKRQDVIDDFLEKEASKPVSNKVIDPASLKWTPSKCS 541
BLAST of Histone acetyltransferase vs. Ensembl Yeast
Match: ESA1 (Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases, functionally complements lethality of the esa1 null mutation [Source:SGD;Acc:S000005770]) HSP 1 Score: 343.584 bits (880), Expect = 2.496e-111 Identity = 195/470 (41.49%), Postives = 269/470 (57.23%), Query Frame = 2
Query: 44 VKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKM-HEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHP 1450
+K ++ +D AEIL N R ++YVH+ YNKRLD+W++ DR+ + E+++P K+ + S +P + + Q+ + S ++ + + D +++ + D N E L +GSM H+ V R+RN++ I++GK I+PWYFSPYP ELT+ D I+I +F L+YF S +R+ +KC LRHPPGNEIYR + +SFFEIDGRK + + +NLCLL+KLFLDHKTLYYD DPFLFY + DE G H+VGYFSKEKES D NVACILTLP YQR GYGKLLIEFSYELSK ENK GSPEKPLSDLGLLSYR+YW T++ ++++ ++ TS+ D+ T T+NI+ Y KGQH+I + + +LD++ AK++ ID L W P
Sbjct: 23 IKCQCWVQKNDEERLAEILSI--NTRKAPPKFYVHYVNYNKRLDEWITTDRINLDKEVLYP--KLKATDEDNKKQKKKKATNTSETP--QDSLQDGVD-------GFSRENTDVMDLDNLNVQGIKDENIS---HEDEIKKLRTSGSMTQNPHE-----VARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHLVGYFSKEKESADGYNVACILTLPQYQRMGYGKLLIEFSYELSKKENKVGSPEKPLSDLGLLSYRAYWSDTLITLLVEHQKE--------------------------------------ITIDEISSMTSMTTTDILHTAKTLNILRYYKGQHIIFLNEDILDRYNRLKAKKRRTIDPNRLIWKP 433
BLAST of Histone acetyltransferase vs. Ensembl Yeast
Match: SAS3 (Histone acetyltransferase catalytic subunit of NuA3 complex; acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; mutant has aneuploidy tolerance; sas3gcn5 double mutation is lethal [Source:SGD;Acc:S000000148]) HSP 1 Score: 242.276 bits (617), Expect = 2.381e-69 Identity = 130/268 (48.51%), Postives = 172/268 (64.18%), Query Frame = 2
Query: 395 QMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSH----QEHQDI------VTRMRN------IDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDE---------EGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVII 1123
+ +L T +D+ F E + G++ + +H QE++D V R++N I+ IVL IKPWY SP+PE + + +FICEFCLKY S + RH KC PPGNEIYR LS +EIDGR+N Y QNLCLLAK F++ KTLYYD +PF+FYIL E ++ FH VGYFSKEK +++D N++CILTLP YQRKGYG+ L+EFSY LS+ E+K G+PEKPLSDLGLL+YR++W EV++
Sbjct: 209 KRTLPTWEDKIKFLTFLENSKSATYINGNVSLCNHNETDQENEDRKKRKGKVPRIKNKVWFSQIEYIVLRNYEIKPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRHQLKCLTFKPPGNEIYRDGKLSVWEIDGRENVLYCQNLCLLAKCFINSKTLYYDVEPFIFYILTEREDTENHPYQNAAKFHFVGYFSKEKFNSNDYNLSCILTLPIYQRKGYGQFLMEFSYLLSRKESKFGTPEKPLSDLGLLTYRTFWKIKCAEVLL 476
BLAST of Histone acetyltransferase vs. Ensembl Yeast
Match: SAS2 (Histone acetyltransferase (HAT) catalytic subunit of the SAS complex; acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family; other members are Sas4p and Sas5p [Source:SGD;Acc:S000004734]) HSP 1 Score: 137.502 bits (345), Expect = 4.962e-36 Identity = 71/173 (41.04%), Postives = 101/173 (58.38%), Query Frame = 2
Query: 611 LDAIFICEFCLKYFKSCFCLQRHLEKCRLRH-PPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIID 1126
LD +F+CE+C KY H+ C ++ PG Y+ + + G K + + Q LCL KL+LD+K++Y+ D + FYI+ Y+ +G+FSK+ S NN+ACIL PPYQR+G G LLIEFSY+LS+LE PE PLS GL+ Y YW Q + +I+
Sbjct: 97 LDTLFVCEYCFKYTDDQTRFVGHVASCPFQYRVPGKIKYKSPEYTIRRVKGSKYQLFCQCLCLFTKLYLDNKSMYFKVDHYEFYIV--YETGSTKPMGFFSKDLVSYQQNNLACILIFPPYQRRGLGLLLIEFSYKLSQLEGVISGPEVPLSPFGLIGYLKYWSQILCWHLIE 267
BLAST of Histone acetyltransferase vs. Ensembl Nematostella
Match: EDO34934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMW6]) HSP 1 Score: 449.129 bits (1154), Expect = 3.252e-151 Identity = 243/507 (47.93%), Postives = 324/507 (63.91%), Query Frame = 2
Query: 38 EGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFP----TKKIHKDXXXXXXXXXXXXNDCSNSPFG---------EANAQEAENVEY--KIRLNSSTSS-----SALKNEDQMSLVTMDDRNCFSYLQEPVANVLP-------QTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
EG ++PV++ +SD + AEI+ RE + EYYVHF ++NKRLD+WV+EDR+ + P TKKI K ++ + + P +ANA + + E K T+S SAL+ + + T+ + P + P Q GS++ + + DIVTRM+NI M+ LGK RIKPWYFSPYP+E T L +++C+FCLK+ KS CL+RH+ KC L HPPGNEIYR +SFFEIDGRKNK+YAQNLCLLAK+FLDHKTLYYDTDPFLFYI+ E D GFHIVGYFSKEKES +D NVACILTLP YQRKGYGKLLIEFSYELSK E KTG+PEKPLSDLGLLSYRSYW QTI+E+++ + + +PPSI++ +++ E TSI +D+ +TL + +I+Y KGQ+++ + K++L+ + +M+KRK RID+ L+W+PKDW+KRG+W
Sbjct: 8 EGCRMPVRMNNSDEWPLAEIISKRE--KGDEFEYYVHFIDFNKRLDEWVTEDRLDKTRIQLPKKEDTKKISKGAAGSRPPSPERDMVNGTGPRTNKILTGRKRKANAMDKSSDEILNKCLGTFETTSPTLVFSALELKQDLHSPTLSGMVRLFFQDSPTKDTPPTKMSSLRQHGSLV--QDRSNDDIVTRMKNIQMVQLGKFRIKPWYFSPYPQEFTNLPMVYLCDFCLKFVKSFHCLKRHMVKCNLFHPPGNEIYRNGTISFFEIDGRKNKQYAQNLCLLAKMFLDHKTLYYDTDPFLFYIMTESDGAGFHIVGYFSKEKESTEDYNVACILTLPQYQRKGYGKLLIEFSYELSKFEGKTGTPEKPLSDLGLLSYRSYWSQTILEILVGLKSEDG----------NPPSITI----------------------NEICELTSIRKEDVVSTLQHLGLIHYYKGQYILSLGKEVLEGHRRAMSKRKIRIDSNCLHWNPKDWAKRGKW 478
BLAST of Histone acetyltransferase vs. Ensembl Nematostella
Match: EDO39884 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8T4]) HSP 1 Score: 317.005 bits (811), Expect = 2.037e-101 Identity = 183/456 (40.13%), Postives = 253/456 (55.48%), Query Frame = 2
Query: 89 AEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRK--YRIDAKLLNWHP 1450
AEI++++ G YYVH+ +N+RLD+WV R+ + + ND + P + + + + E KI N + +++Q+ A + P T ++ +EH+ I T+++ ID GK I WYFSPYP+E +L+ ++ICE+C+KY K + H+ KC +R PPG EIYRK +S +E+DG++ K Y QN+CLLAKLFLDHKTLY+D +PFLFYIL E D EG H+VGYFSKEKES D NNVACILTLPPYQRKGYGK LI FSYELSK+E GSPEKPLSDLG LSYRSYW +++++ + ++S+K D+ TSI +D+ TL ++N++ Y KGQHVI VT K++++ S RK +D L W P
Sbjct: 12 AEIIQSKVEDD-GKTVYYVHYHGFNRRLDEWVEAARVDLQQ-----------------------ND--DKPIID-DKLDVDGPERKITRNQKRKHDEI-----------------NHVQKTYAEMDPTTAAL----EKEHEAI-TKIKFIDKAQFGKYEIDTWYFSPYPDEYGKLNKLWICEYCIKYMKFEKTFRDHIGKCEMRQPPGKEIYRKGSVSVYEVDGKEQKLYCQNICLLAKLFLDHKTLYFDVEPFLFYILTEVDREGAHMVGYFSKEKESPDGNNVACILTLPPYQRKGYGKFLINFSYELSKIEQTVGSPEKPLSDLGKLSYRSYWSWVLLDILRNFRG----------------TLSIK----------------------DLSAMTSITQEDIIGTLQSLNMVKYWKGQHVICVTPKLVEEHVKSAQYRKPVLTVDNSCLRWAP 380
BLAST of Histone acetyltransferase vs. Ensembl Nematostella
Match: EDO39738 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S982]) HSP 1 Score: 170.629 bits (431), Expect = 1.171e-49 Identity = 76/115 (66.09%), Postives = 97/115 (84.35%), Query Frame = 2
Query: 776 YAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVI 1120
Y QNLCLLAKLFLDHKTLYYD +PFLFY+L + D++G H+VGYFSKEK NV+CI+T+P YQR+G+G+LLI+FSY LS++E ++GSPEKPLSDLGL+SYRSYW ++E +
Sbjct: 17 YCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDKKGCHLVGYFSKEKSCQQKYNVSCIMTMPHYQRQGFGRLLIDFSYLLSRIEGQSGSPEKPLSDLGLISYRSYWKSVMLEYM 131
BLAST of Histone acetyltransferase vs. Ensembl Nematostella
Match: EDO39739 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S983]) HSP 1 Score: 93.2041 bits (230), Expect = 7.645e-23 Identity = 51/117 (43.59%), Postives = 64/117 (54.70%), Query Frame = 2
Query: 407 VTMDDRNCFSYLQEPVANVLPQTGSMMVT-SHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEI 754
VT D F QE MMVT + H ++ R+ +I G+ I WY SPYP+E L +FICEFCLKY KS +QRH+ KC HPP NEIYRK+ +S FE+
Sbjct: 1 VTEADLALFKKAQEKA------NSKMMVTPTSAPHPNV----RSPALIQFGRHEIHTWYSSPYPQEYARLSKLFICEFCLKYMKSSSIVQRHITKCGWFHPPANEIYRKDDISVFEV 107
BLAST of Histone acetyltransferase vs. Ensembl Nematostella
Match: EDO29009 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4V3]) HSP 1 Score: 91.6633 bits (226), Expect = 7.004e-22 Identity = 54/162 (33.33%), Postives = 86/162 (53.09%), Query Frame = 2
Query: 974 RKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKY---RIDAKLLNWHP 1450
++GYGK+LI+FSY LSK E K GSPEKPLSDLGL+SYRSYW +++ + + +IS+K D+ ++T+I+P D+ +TL + ++ Y KG+H+++ + ++ ++F +A R ID L W P
Sbjct: 2 KQGYGKMLIDFSYLLSKTECKVGSPEKPLSDLGLISYRSYWKNIVLKYL---------------HCYGYDTISIK----------------------DISQETAIHPNDIVSTLQYLGLLKYWKGKHLVLRSPELFEEFAKRVAARPANYQEIDPTCLQWSP 126
BLAST of Histone acetyltransferase vs. Ensembl Medaka
Match: kat5b (lysine acetyltransferase 5 [Source:NCBI gene;Acc:101161500]) HSP 1 Score: 417.542 bits (1072), Expect = 3.473e-137 Identity = 199/335 (59.40%), Postives = 250/335 (74.63%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DI+TRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D+ +P T+ +++ E TS+ +D+ +TL +N+I Y KGQ+++ ++++++D + +M KR RID K L++ PKDWSKRG+W
Sbjct: 280 TGSLV--SDRSHDDIITRMKNIECIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKNYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMDLKPD-----------------------NGERPQITI---------NEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEEIVDGHEKAMQKRHLRIDPKCLHFTPKDWSKRGKW 580 HSP 2 Score: 58.151 bits (139), Expect = 2.689e-8 Identity = 30/71 (42.25%), Postives = 46/71 (64.79%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDS---DIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
++ EG +LPV K+ D + AEIL +E G K +YVH+ ++NKRLD+WV+ DR+ M ++ FP K+
Sbjct: 9 EIVEGCRLPVLRKNQEHEDEWPLAEILSLKEVS--GRKLFYVHYIDFNKRLDEWVTADRLDMKKLQFPKKE 77
BLAST of Histone acetyltransferase vs. Ensembl Medaka
Match: kat5b (lysine acetyltransferase 5 [Source:NCBI gene;Acc:101161500]) HSP 1 Score: 417.157 bits (1071), Expect = 3.737e-137 Identity = 199/335 (59.40%), Postives = 250/335 (74.63%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DI+TRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D+ +P T+ +++ E TS+ +D+ +TL +N+I Y KGQ+++ ++++++D + +M KR RID K L++ PKDWSKRG+W
Sbjct: 263 TGSLV--SDRSHDDIITRMKNIECIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKNYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMDLKPD-----------------------NGERPQITI---------NEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEEIVDGHEKAMQKRHLRIDPKCLHFTPKDWSKRGKW 563 HSP 2 Score: 58.151 bits (139), Expect = 2.526e-8 Identity = 30/71 (42.25%), Postives = 46/71 (64.79%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDS---DIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
++ EG +LPV K+ D + AEIL +E G K +YVH+ ++NKRLD+WV+ DR+ M ++ FP K+
Sbjct: 9 EIVEGCRLPVLRKNQEHEDEWPLAEILSLKEVS--GRKLFYVHYIDFNKRLDEWVTADRLDMKKLQFPKKE 77
BLAST of Histone acetyltransferase vs. Ensembl Medaka
Match: kat5b (lysine acetyltransferase 5 [Source:NCBI gene;Acc:101161500]) HSP 1 Score: 416.772 bits (1070), Expect = 4.632e-137 Identity = 199/335 (59.40%), Postives = 250/335 (74.63%), Query Frame = 2
Query: 473 TGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
TGS++ S + H DI+TRM+NI+ I LG+ R+KPWYFSPYP+ELT L +++CEFCLKY KS CLQRHL KC LRHPPGNEIYRK +SFFEIDGRKNK Y+QNLCLLAK FLDHKTLYYDTDPFLFY++ EYD +GFHIVGYFSKEKES +D NVACILTLPPYQR+GYGKLLIEFSYELSK+E KTG+PEKPLSDLGLLSYRSYW QTI+E+++D+ +P T+ +++ E TS+ +D+ +TL +N+I Y KGQ+++ ++++++D + +M KR RID K L++ PKDWSKRG+W
Sbjct: 263 TGSLV--SDRSHDDIITRMKNIECIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLTKCNLRHPPGNEIYRKGTISFFEIDGRKNKNYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMDLKPD-----------------------NGERPQITI---------NEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEEIVDGHEKAMQKRHLRIDPKCLHFTPKDWSKRGKW 563 HSP 2 Score: 58.151 bits (139), Expect = 2.683e-8 Identity = 30/71 (42.25%), Postives = 46/71 (64.79%), Query Frame = 2
Query: 29 KLCEGVKLPVKLKDS---DIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKK 232
++ EG +LPV K+ D + AEIL +E G K +YVH+ ++NKRLD+WV+ DR+ M ++ FP K+
Sbjct: 9 EIVEGCRLPVLRKNQEHEDEWPLAEILSLKEVS--GRKLFYVHYIDFNKRLDEWVTADRLDMKKLQFPKKE 77
BLAST of Histone acetyltransferase vs. Ensembl Medaka
Match: kat8 (lysine acetyltransferase 8 [Source:NCBI gene;Acc:101155932]) HSP 1 Score: 334.339 bits (856), Expect = 3.910e-106 Identity = 188/459 (40.96%), Postives = 266/459 (57.95%), Query Frame = 2
Query: 80 YHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRK--YRIDAKLLNWHP 1450
+H AE++++R N++ G +E+YVH+ +N+RLD+WV + R+ + + V KD+ S D + P E KI N + D+++ ++Q+ A + P T ++ +EH+ I T+++ +D I +G I WYFSP+PE+ + ++ICE+CLKY K + HL C+ R PPG EIYR++ +S +E+DGR +K Y QNLCLLAKLFLDHKTLY+D +PF+FYIL E +++G HIVGYFSKEKES D NNVACILTLPPYQR+GYGK LI FSYELSKLEN GSPEKPLSDLG LSYRSYW ++E++ D ++S+K D+ + TSI D+ +TL ++N++ Y KGQHVI VT K++++ S +K +D L W P
Sbjct: 106 WHTAEVIQSRLNEQEGREEFYVHYVGFNRRLDEWVGKSRLALTKTV-------KDAVRKSTEVGGV-GDLGDQP------------ERKITRNQK------RKHDEIN-----------HVQKTYAEMDPTTAAL----EKEHEAI-TKVKYVDKIQIGNFEIDAWYFSPFPEDYGKQPKLWICEYCLKYMKYEKTFRYHLSHCQWRQPPGKEIYRRSNISVYEVDGRDHKIYCQNLCLLAKLFLDHKTLYFDVEPFIFYILTEVNKQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLENSVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG----------------TLSIK----------------------DLSQMTSITQSDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDTMCLKWAP 484
BLAST of Histone acetyltransferase vs. Ensembl Medaka
Match: kat8 (lysine acetyltransferase 8 [Source:NCBI gene;Acc:101155932]) HSP 1 Score: 333.954 bits (855), Expect = 4.887e-106 Identity = 188/459 (40.96%), Postives = 266/459 (57.95%), Query Frame = 2
Query: 80 YHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRK--YRIDAKLLNWHP 1450
+H AE++++R N++ G +E+YVH+ +N+RLD+WV + R+ + + V KD+ S D + P E KI N + D+++ ++Q+ A + P T ++ +EH+ I T+++ +D I +G I WYFSP+PE+ + ++ICE+CLKY K + HL C+ R PPG EIYR++ +S +E+DGR +K Y QNLCLLAKLFLDHKTLY+D +PF+FYIL E +++G HIVGYFSKEKES D NNVACILTLPPYQR+GYGK LI FSYELSKLEN GSPEKPLSDLG LSYRSYW ++E++ D ++S+K D+ + TSI D+ +TL ++N++ Y KGQHVI VT K++++ S +K +D L W P
Sbjct: 106 WHTAEVIQSRLNEQEGREEFYVHYVGFNRRLDEWVGKSRLALTKTV-------KDAVRKSTEVGGV-GDLGDQP------------ERKITRNQK------RKHDEIN-----------HVQKTYAEMDPTTAAL----EKEHEAI-TKVKYVDKIQIGNFEIDAWYFSPFPEDYGKQPKLWICEYCLKYMKYEKTFRYHLSHCQWRQPPGKEIYRRSNISVYEVDGRDHKIYCQNLCLLAKLFLDHKTLYFDVEPFIFYILTEVNKQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLENSVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRG----------------TLSIK----------------------DLSQMTSITQSDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDTLCLKWAP 484
BLAST of Histone acetyltransferase vs. Planmine SMEST
Match: SMESG000049001.1 (SMESG000049001.1) HSP 1 Score: 897.501 bits (2318), Expect = 0.000e+0 Identity = 463/486 (95.27%), Postives = 464/486 (95.47%), Query Frame = 2
Query: 20 MFNKLCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 1477
MFNKLCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDSSTASLTALVSTNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVANSADGAANSSSSAFDPPSISL +DVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW
Sbjct: 1 MFNKLCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDSSTASLTALVSTNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVANSADGAANSSSSAFDPPSISL----------------------NDVVEKTSINPKDLNATLNTMNIIYYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHPKDWSKRGRW 464
BLAST of Histone acetyltransferase vs. Planmine SMEST
Match: SMESG000040171.1 (SMESG000040171.1) HSP 1 Score: 271.166 bits (692), Expect = 1.174e-82 Identity = 163/441 (36.96%), Postives = 226/441 (51.25%), Query Frame = 2
Query: 134 EYYVHFDEYNKRLDDWVSEDRMKMHEMVFPTKKIHKDXXXXXXXXXXXXNDCSNSPFGEANAQEAENVEYKIRLNSSTSSSALKNEDQMSLVTMDDRNCFSYLQEPVANVLPQTGSMMVTSHQEHQDIVTRMRNIDMIVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIIDVXXXXXXXXXXXXXXFDPPSISLKYEFTSWKPLATVFIYIYVCVCSDVVEKTSINPKDLNATLNTMNII--YYSKGQHVIVVTKKMLDKFKASMAKRKYRIDAKLLNWHP 1450
EY+VH+ ++RLD+WV + + + N +++I+ S ++ AL E +T + + + + S+ + +EHQ TR++ I+ I G I+ WYFSPYPE+ + ++ICE+CLKY K H +C + PPG EIYRK LS FEIDG + K Y QNLCLLAKLFLDHKTLYYD PF+FY+LCE D EG H+VGYFSKEK S D+ N+ACILTLPP+QRKGYGK LI FSYEL+K+E GSPEKPLSDLG LSYRSYW I ++D P+ S++ D+ T I+ D+ + L + N++ Y+ G+ + + K ++ + K+ +ID L W P
Sbjct: 40 EYFVHYHGNDRRLDEWVPYENIDV------------------------------------------NSKFEIKEESCSNLLALATECSDGRLTRHQKRKINEIYHGRSIDEAPMDSITLKLEKEHQ-AFTRVKYIETIRYGTYEIETWYFSPYPEDYRKFQKLYICEYCLKYMKLEDSFLCHQSQCPQKQPPGKEIYRKENLSVFEIDGNEKKLYCQNLCLLAKLFLDHKTLYYDVAPFMFYVLCEVDREGCHLVGYFSKEKISIDNYNLACILTLPPFQRKGYGKFLIAFSYELAKIEKMIGSPEKPLSDLGWLSYRSYWEYVIFTYLLDY-----------------PNSSIE----------------------DISTATCISIDDIKSVLESHNLMKYYHRHGKELQISRKSLIHYLENFNNKKPIQIDKSCLKWLP 398
BLAST of Histone acetyltransferase vs. Planmine SMEST
Match: SMESG000062900.1 (SMESG000062900.1) HSP 1 Score: 221.861 bits (564), Expect = 2.572e-60 Identity = 105/194 (54.12%), Postives = 132/194 (68.04%), Query Frame = 2
Query: 545 IVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIID 1126
I +G+ I WY +PYP E L+ ++ICE+CLK KS H++KC PPGNEIYR LS FE+DG +K Y Q LCLLAKLFLDHKTLYYD +PFLFY+ + HI+GYFSKEK S N++CI+ LPPYQ+ YG+ LI+FSY LS+ E + GSPEKPLS LG +SY SYW I+ I++
Sbjct: 656 IQIGRHVIDTWYSAPYPSEYARLNVLYICEYCLKPIKSYDVYVMHMQKCTFYFPPGNEIYRNGDLSVFEVDGYVSKLYCQQLCLLAKLFLDHKTLYYDVEPFLFYVAVISKNKSSHIIGYFSKEKRSTHKYNLSCIMVLPPYQKYNYGRFLIDFSYLLSRKEGQCGSPEKPLSILGRISYESYWKSKILPYILN 849
BLAST of Histone acetyltransferase vs. Planmine SMEST
Match: SMESG000062900.1 (SMESG000062900.1) HSP 1 Score: 221.861 bits (564), Expect = 2.648e-60 Identity = 105/194 (54.12%), Postives = 132/194 (68.04%), Query Frame = 2
Query: 545 IVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIID 1126
I +G+ I WY +PYP E L+ ++ICE+CLK KS H++KC PPGNEIYR LS FE+DG +K Y Q LCLLAKLFLDHKTLYYD +PFLFY+ + HI+GYFSKEK S N++CI+ LPPYQ+ YG+ LI+FSY LS+ E + GSPEKPLS LG +SY SYW I+ I++
Sbjct: 658 IQIGRHVIDTWYSAPYPSEYARLNVLYICEYCLKPIKSYDVYVMHMQKCTFYFPPGNEIYRNGDLSVFEVDGYVSKLYCQQLCLLAKLFLDHKTLYYDVEPFLFYVAVISKNKSSHIIGYFSKEKRSTHKYNLSCIMVLPPYQKYNYGRFLIDFSYLLSRKEGQCGSPEKPLSILGRISYESYWKSKILPYILN 851
BLAST of Histone acetyltransferase vs. Planmine SMEST
Match: SMESG000062900.1 (SMESG000062900.1) HSP 1 Score: 221.861 bits (564), Expect = 2.771e-60 Identity = 105/194 (54.12%), Postives = 132/194 (68.04%), Query Frame = 2
Query: 545 IVLGKSRIKPWYFSPYPEELTELDAIFICEFCLKYFKSCFCLQRHLEKCRLRHPPGNEIYRKNPLSFFEIDGRKNKKYAQNLCLLAKLFLDHKTLYYDTDPFLFYILCEYDEEGFHIVGYFSKEKESNDDNNVACILTLPPYQRKGYGKLLIEFSYELSKLENKTGSPEKPLSDLGLLSYRSYWCQTIMEVIID 1126
I +G+ I WY +PYP E L+ ++ICE+CLK KS H++KC PPGNEIYR LS FE+DG +K Y Q LCLLAKLFLDHKTLYYD +PFLFY+ + HI+GYFSKEK S N++CI+ LPPYQ+ YG+ LI+FSY LS+ E + GSPEKPLS LG +SY SYW I+ I++
Sbjct: 656 IQIGRHVIDTWYSAPYPSEYARLNVLYICEYCLKPIKSYDVYVMHMQKCTFYFPPGNEIYRNGDLSVFEVDGYVSKLYCQQLCLLAKLFLDHKTLYYDVEPFLFYVAVISKNKSSHIIGYFSKEKRSTHKYNLSCIMVLPPYQKYNYGRFLIDFSYLLSRKEGQCGSPEKPLSILGRISYESYWKSKILPYILN 849 The following BLAST results are available for this feature:
BLAST of Histone acetyltransferase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Histone acetyltransferase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Histone acetyltransferase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Histone acetyltransferase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Histone acetyltransferase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Histone acetyltransferase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Histone acetyltransferase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Histone acetyltransferase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Histone acetyltransferase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Histone acetyltransferase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Histone acetyltransferase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of Histone acetyltransferase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Histone acetyltransferase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Histone acetyltransferase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30006506 ID=SMED30006506|Name=Histone acetyltransferase|organism=Schmidtea mediterranea sexual|type=transcript|length=2255bpback to top protein sequence of SMED30006506-orf-1 >SMED30006506-orf-1 ID=SMED30006506-orf-1|Name=SMED30006506-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=487bp MFNKLCEGVKLPVKLKDSDIYHFAEILKARENKRLGTKEYYVHFDEYNKRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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