Histone-lysine N-methyltransferase SETMAR

Overview
NameHistone-lysine N-methyltransferase SETMAR
Smed IDSMED30006498
Length (bp)961
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Histone-lysine N-methyltransferase SETMAR (SMED30006498) t-SNE clustered cells

Violin plots show distribution of expression levels for Histone-lysine N-methyltransferase SETMAR (SMED30006498) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Histone-lysine N-methyltransferase SETMAR (SMED30006498) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Histone-lysine N-methyltransferase SETMAR (SMED30006498) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30006498

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30006498h1SMcG0014262 dd_Smed_v4_9316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30006498h1SMcG0014262 dd_Smed_v4_9316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30006498h1SMcG0014262 dd_Smed_v4_9316_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Category 3 cellSMED30006498h1SMcG0014262 GAKN01015423.1SmedAsxl_pearson_GAKN01PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30006498h1SMcG0014262 GAKN01015423.1SmedAsxl_pearson_GAKN01PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parapharyngeal regionSMED30006498h1SMcG0014262 DN303757smed_ncbi_20240424PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30006498h1SMcG0014262 DN303757smed_ncbi_20240424PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymal cellSMED30006498h1SMcG0014262 DN303757smed_ncbi_20240424PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Human
Match: SETMAR (SET domain and mariner transposase fusion gene [Source:HGNC Symbol;Acc:HGNC:10762])

HSP 1 Score: 62.003 bits (149), Expect = 4.916e-10
Identity = 33/85 (38.82%), Postives = 47/85 (55.29%), Query Frame = 2 
Query:  173 WF*HFNQNNFDLTDAPRSPREVEIPDNEIMVLIEAGQHKTTRNIPEILEINH*TVSRQLRNLGIVSKVDVWVQRDLTEKNLKERL 427
            WF  F + +  L D  RS R  E+ ++++  +IEA    TTR + E L +NH TV R L+ +G V K+D WV  +LTE     R 
Sbjct:  389 WFKKFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRF 473

HSP 2 Score: 52.373 bits (124), Expect = 7.456e-7
Identity = 29/87 (33.33%), Postives = 52/87 (59.77%), Query Frame = 1 
Query:  517 KARLHPKKVMLSNWWN*EGIFLYEHI*-NDTINSDKY*SHLNELKLATEQK*PALVNQRCIVF*YYNAKQHVSLAARNRLSQLNFDV 774
            K  LHPKKVM++ WW+  G+  Y  +   +TI S+KY   ++E+    ++   ALVN++  +  + NA+ HV+     +L++L ++V
Sbjct:  523 KPILHPKKVMVTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEV 609
[Close]
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Human
Match: SETMAR (SET domain and mariner transposase fusion gene [Source:HGNC Symbol;Acc:HGNC:10762])

HSP 1 Score: 62.003 bits (149), Expect = 5.063e-10
Identity = 33/85 (38.82%), Postives = 47/85 (55.29%), Query Frame = 2 
Query:  173 WF*HFNQNNFDLTDAPRSPREVEIPDNEIMVLIEAGQHKTTRNIPEILEINH*TVSRQLRNLGIVSKVDVWVQRDLTEKNLKERL 427
            WF  F + +  L D  RS R  E+ ++++  +IEA    TTR + E L +NH TV R L+ +G V K+D WV  +LTE     R 
Sbjct:  250 WFKKFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRF 334

HSP 2 Score: 51.9878 bits (123), Expect = 7.943e-7
Identity = 29/87 (33.33%), Postives = 52/87 (59.77%), Query Frame = 1 
Query:  517 KARLHPKKVMLSNWWN*EGIFLYEHI*-NDTINSDKY*SHLNELKLATEQK*PALVNQRCIVF*YYNAKQHVSLAARNRLSQLNFDV 774
            K  LHPKKVM++ WW+  G+  Y  +   +TI S+KY   ++E+    ++   ALVN++  +  + NA+ HV+     +L++L ++V
Sbjct:  384 KPILHPKKVMVTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEV 470
[Close]
BLAST of Histone-lysine N-methyltransferase SETMAR vs. UniProt/SwissProt
Match: sp|Q53H47|SETMR_HUMAN (Histone-lysine N-methyltransferase SETMAR OS=Homo sapiens OX=9606 GN=SETMAR PE=1 SV=2)

HSP 1 Score: 62.003 bits (149), Expect = 2.361e-9
Identity = 33/85 (38.82%), Postives = 47/85 (55.29%), Query Frame = 2 
Query:  173 WF*HFNQNNFDLTDAPRSPREVEIPDNEIMVLIEAGQHKTTRNIPEILEINH*TVSRQLRNLGIVSKVDVWVQRDLTEKNLKERL 427
            WF  F + +  L D  RS R  E+ ++++  +IEA    TTR + E L +NH TV R L+ +G V K+D WV  +LTE     R 
Sbjct:  389 WFKKFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREVAEELNVNHSTVVRHLKQIGKVKKLDKWVPHELTENQKNRRF 473

HSP 2 Score: 52.373 bits (124), Expect = 3.581e-6
Identity = 29/87 (33.33%), Postives = 52/87 (59.77%), Query Frame = 1 
Query:  517 KARLHPKKVMLSNWWN*EGIFLYEHI*-NDTINSDKY*SHLNELKLATEQK*PALVNQRCIVF*YYNAKQHVSLAARNRLSQLNFDV 774
            K  LHPKKVM++ WW+  G+  Y  +   +TI S+KY   ++E+    ++   ALVN++  +  + NA+ HV+     +L++L ++V
Sbjct:  523 KPILHPKKVMVTIWWSAAGLIHYSFLNPGETITSEKYAQEIDEMNQKLQRLQLALVNRKGPILLHDNARPHVAQPTLQKLNELGYEV 609
[Close]
BLAST of Histone-lysine N-methyltransferase SETMAR vs. UniProt/SwissProt
Match: sp|Q7JQ07|MOS1T_DROMA (Mariner Mos1 transposase OS=Drosophila mauritiana OX=7226 GN=mariner\T PE=1 SV=1)

HSP 1 Score: 55.0694 bits (131), Expect = 2.549e-7
Identity = 32/120 (26.67%), Postives = 55/120 (45.83%), Query Frame = 2 
Query:   80 TVCCFSFRKKKCCPDKKEIYDDALYDSLY-----RKWF*HFNQNNFDLTDAPRSPREVEIPDNEIMVLIEAGQHKTTRNIPEILEINH*TVSRQLRNLGIVSKVDVWVQRDLTEKNLKER 424
            TV  F F  KK   +   +  +A  + +       +WF  F   +FD+ D           D E+  L++    +T + + E LE++   VS +LR +G + KV  WV  +L E+ ++ R
Sbjct:   13 TVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKKCERWFQRFKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAVSNRLREMGKIQKVGRWVPHELNERQMERR 132
[Close]
BLAST of Histone-lysine N-methyltransferase SETMAR vs. TrEMBL
Match: A0A3L8DAH9 (HTH_48 domain-containing protein OS=Ooceraea biroi OX=2015173 GN=DMN91_011221 PE=4 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 2.749e-35
Identity = 56/125 (44.80%), Postives = 74/125 (59.20%), Query Frame = 1 
Query:  412 FERALGNGR*KWISYTKKLF*IIKISYSTTGEPSV---KARLHPKKVMLSNWWN*EGIFLYEHI*-NDTINSDKY*SHLNELKLATEQK*PALVNQRCIVF*YYNAKQHVSLAARNRLSQLNFDV 774
            F + L  G  KWI Y        K S+    EP++   KA LHPKKVML  WW+ +GI  YE +  N TIN+DKY S L+ELK A ++K P L N++ +VF   NA+ HVSL  R +L +  +DV
Sbjct:  145 FLKQLVMGDEKWIIYNNVER---KRSWGKRNEPALTTPKAGLHPKKVMLCVWWDWKGILYYELLPHNQTINADKYCSQLDELKTAIQEKRPELANRKGVVFHQDNARPHVSLTTRQKLLEFGWDV 266

HSP 2 Score: 71.2478 bits (173), Expect = 2.749e-35
Identity = 40/96 (41.67%), Postives = 54/96 (56.25%), Query Frame = 2 
Query:  140 DDALYDSLYRKWF*HFNQNNFDLTDAPRSPREVEIPDNEIMVLIEAGQHKTTRNIPEILEINH*TVSRQLRNLGIVSKVDVWVQRDLTEKNLKERL 427
            + AL +   RKWF  F   +F+L D  R  R     D++I  LIE     TTR + EIL+I+  TV   +  LG VS+ DVWV  +L EKNL +R+
Sbjct:   35 EGALAERTVRKWFAKFKAGDFNLKDQERLGRPSTTDDDQIKTLIENNPRYTTRELAEILKISKTTVHDHVVKLGYVSRYDVWVPHNLAEKNLMDRI 130

HSP 3 Score: 39.6614 bits (91), Expect = 2.749e-35
Identity = 22/41 (53.66%), Postives = 24/41 (58.54%), Query Frame = 3 
Query:  771 CLVHASYSLD-----FYLFRSLQNRLGCKKFCFLKDLKNHL 878
             L H  YS D     F+LFRSLQN L  K F  L D+KNHL
Sbjct:  266 VLPHPPYSPDIAPSDFHLFRSLQNSLSGKNFNSLIDIKNHL 306
[Close]
BLAST of Histone-lysine N-methyltransferase SETMAR vs. TrEMBL
Match: A0A4W2GJC4 (HTH_48 domain-containing protein OS=Bos indicus x Bos taurus OX=30522 GN=NUDT15 PE=4 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 4.125e-33
Identity = 50/112 (44.64%), Postives = 68/112 (60.71%), Query Frame = 2 
Query:  104 KKKCCPDKKEIYDDALYDSLYRKWF*HFNQNNFDLTDAPRSPREVEIPDNEIMVLIEAGQHKTTRNIPEILEINH*TVSRQLRNLGIVSKVDVWVQRDLTEKNLKERLVTED 439
            KKK C    E  + A+ +   +KWF  F   +F L DAPRS R VE+  N+I  LIE+ QH TTR I +IL+I+  +V   L  LG V++ DVWV   L++KNL +R+ T D
Sbjct:   26 KKKIC---AEYGEGAVTERTCQKWFAKFRAGDFSLYDAPRSGRPVEVDSNQIETLIESNQHYTTREIADILKISKSSVENHLHQLGYVNRFDVWVPLKLSQKNLLDRISTCD 134

HSP 2 Score: 82.4185 bits (202), Expect = 4.125e-33
Identity = 64/172 (37.21%), Postives = 91/172 (52.91%), Query Frame = 1 
Query:  481 KISYSTTGEPSV---KARLHPKKVMLSNWWN*EGIFLYEHI*-NDTINSDKY*SHLNELKLATEQK*PALVNQRCIVF*YYNAKQHVSLAARNRLSQLNFDV---*SMHHTLSISTY--LDHFKIG*VVKNFVSXXXXXXXXXXXXPQ---RFYDCGIM*LPETCRKMIELN 960
            K S+    EP     KA LHPK+VML  WW+  G+  YE +  N +INS KY S L++LK A  +K P   +++CI+F   NA+ HVSL  R +L QL ++V         ++ S Y      +     KNF S +  K  L     Q   +F++ GIM LPE  +K++E N
Sbjct:  165 KRSWDKRNEPPPAMPKAGLHPKRVMLCIWWDWMGVLYYELLPENQSINSKKYCSQLDQLKAALNEKRPESADRKCIIFHQDNARPHVSLMTRQKLLQLGWEVLIPPPYSPDIAPSDYHLFRSLQNSLNGKNFSSLEDCKRHLEQFFAQKDKKFWEDGIMKLPEKWQKVVEQN 336
[Close]
BLAST of Histone-lysine N-methyltransferase SETMAR vs. TrEMBL
Match: A0A3Q1LQI9 (HTH_48 domain-containing protein OS=Bos taurus OX=9913 GN=NUDT15 PE=4 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 1.424e-32
Identity = 50/112 (44.64%), Postives = 68/112 (60.71%), Query Frame = 2 
Query:  104 KKKCCPDKKEIYDDALYDSLYRKWF*HFNQNNFDLTDAPRSPREVEIPDNEIMVLIEAGQHKTTRNIPEILEINH*TVSRQLRNLGIVSKVDVWVQRDLTEKNLKERLVTED 439
            KKK C    E  + A+ +   +KWF  F   +F L DAPRS R VE+  N+I  LIE+ QH TTR I +IL+I+  +V   L  LG V++ DVWV   L++KNL +R+ T D
Sbjct:   26 KKKIC---AEYGEGAVTERTCQKWFAKFRAGDFSLYDAPRSGRPVEVDSNQIETLIESNQHYTTREIADILKISKSSVENHLHQLGYVNRFDVWVPLKLSQKNLLDRISTCD 134

HSP 2 Score: 80.4925 bits (197), Expect = 1.424e-32
Identity = 63/172 (36.63%), Postives = 91/172 (52.91%), Query Frame = 1 
Query:  481 KISYSTTGEPSV---KARLHPKKVMLSNWWN*EGIFLYEHI*-NDTINSDKY*SHLNELKLATEQK*PALVNQRCIVF*YYNAKQHVSLAARNRLSQLNFDV---*SMHHTLSISTY--LDHFKIG*VVKNFVSXXXXXXXXXXXXPQ---RFYDCGIM*LPETCRKMIELN 960
            K S+    EP     KA LHPK+VML  WW+  G+  YE +  N +INS KY S L++LK A  +K P   +++CI+F   NA+ HVSL  R +L QL ++V         ++ S Y      +     KNF S +  K  L     Q   +F++ GIM LPE  +K+++ N
Sbjct:  165 KRSWDKRNEPPPAMPKAGLHPKRVMLCIWWDWMGVLYYELLPENQSINSKKYCSQLDQLKAALNEKRPESADRKCIIFHQDNARPHVSLMTRQKLLQLGWEVLIPPPYSPDIAPSDYHLFRSLQNSLNGKNFSSLEDCKRHLEQFFAQKDKKFWEDGIMKLPEKWQKVVKQN 336
[Close]
BLAST of Histone-lysine N-methyltransferase SETMAR vs. TrEMBL
Match: Q8I8E6 (Ccmar2 transposase OS=Ceratitis capitata OX=7213 PE=4 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 1.426e-31
Identity = 78/201 (38.81%), Postives = 107/201 (53.23%), Query Frame = 1 
Query:  406 EKFERALGNGR*KWISYT--KKLF*IIKISYSTTGEPS---VKARLHPKKVMLSNWWN*EGIFLYEHI*-NDTINSDKY*SHLNELKLATEQK*PALVNQRCIVF*YYNAKQHVSLAARNRLSQLNFDV*SMHHT-----LSISTY-----LDHFKIG*VVKNFVSXXXXXXXXXXXXPQRFYDCGIM*LPETCRKMIELN 960
            + F + L  G  KW+ Y   K+     K S+S  GEP+    KA +H KKV+LS WW+ +GI  +E +  N TINSD Y   L +L  A E+K P L N++ IVF + NA+ H SLA R +L +L +DV  + H      L+ S Y     L +   G    N    K   I  F  K Q+FY+ GIM LPE  +K+I+ N
Sbjct:  143 DPFLKRLITGDEKWVVYNNIKR-----KRSWSRPGEPTQTTSKADIHQKKVLLSVWWDYKGIVYFELLPPNRTINSDVYIEQLTKLNNAVEEKRPELTNRKSIVFHHDNARPHTSLATRQKLLELGWDV--LPHPPYSPDLAPSDYFLFRSLQNSLNGKNFNNDDDVKSYLIQFFANKNQKFYERGIMMLPERWQKIIDQN 336

HSP 2 Score: 78.5666 bits (192), Expect = 1.426e-31
Identity = 44/129 (34.11%), Postives = 69/129 (53.49%), Query Frame = 2 
Query:   56 QNERSFYVTVCCFSFRKKKCCPDKKE----IY-DDALYDSLYRKWF*HFNQNNFDLTDAPRSPREVEIPDNEIMVLIEAGQHKTTRNIPEILEINH*TVSRQLRNLGIVSKVDVWVQRDLTEKNLKERL 427
            +N++  +  +  F FRK K      +    +Y D+AL +   + WF  F   +F L D  RS R VE+ D  I  +I++ +H TTR I E L ++H  +   L+ LG V K+D WV  +L E +L +R+
Sbjct:    2 ENQKEHFRHILLFYFRKGKTASQAHKKLCAVYGDEALKERQCQNWFAKFRSGDFSLKDEKRSGRPVEVDDALIKAIIDSDRHSTTREIAEKLHVSHTCIENHLKQLGYVQKLDTWVPHELKETHLTQRI 130
[Close]
BLAST of Histone-lysine N-methyltransferase SETMAR vs. TrEMBL
Match: A0A068PBT8 (Transposase OS=Heteropoda venatoria OX=152925 GN=mariner PE=4 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 8.142e-31
Identity = 46/128 (35.94%), Postives = 70/128 (54.69%), Query Frame = 2 
Query:   59 NERSFYVTVCCFSFRKKKCCPDKK----EIY-DDALYDSLYRKWF*HFNQNNFDLTDAPRSPREVEIPDNEIMVLIEAGQHKTTRNIPEILEINH*TVSRQLRNLGIVSKVDVWVQRDLTEKNLKERL 427
            NE+  +  +  F FRK K          ++Y D+AL +   + WF  F   +F L D  RS R VE+ D +I  +I++ +H TTR I E L ++H  +   L+ LG V K+DVWV  +L E +L +R+
Sbjct:    3 NEKEHFRNILLFYFRKGKNASQAHKKLCDVYGDEALKERQCQNWFAKFRSGDFSLKDEKRSGRPVEVDDAQIKAIIDSDRHSTTREIAEKLHVSHTCIENHLKQLGYVQKLDVWVPHELKETHLTQRI 130

HSP 2 Score: 80.8777 bits (198), Expect = 8.142e-31
Identity = 75/201 (37.31%), Postives = 105/201 (52.24%), Query Frame = 1 
Query:  406 EKFERALGNGR*KWISYT--KKLF*IIKISYSTTGE---PSVKARLHPKKVMLSNWWN*EGIFLYEHI*-NDTINSDKY*SHLNELKLATEQK*PALVNQRCIVF*YYNAKQHVSLAARNRLSQLNFDV*SMHH-----TLSISTY-----LDHFKIG*VVKNFVSXXXXXXXXXXXXPQRFYDCGIM*LPETCRKMIELN 960
            + F + L  G  KW+ Y   K+     K S+S  GE    + KA +H KKV+LS WW+ +GI  +E +  N TINSD Y   L +L  A E+K P L N++ +VF + NA+ H SL  R +L +L +DV  + H      L+ S Y     L +   G    N    K   I  F  K Q+FY+ GIM LPE  +K+I+ N
Sbjct:  143 DPFLKRLITGDEKWVVYNNIKR-----KRSWSRPGEHTQTTSKADIHQKKVLLSVWWDYKGIIYFELLPPNRTINSDVYNEQLTKLNNAVEKKRPELTNRKGVVFHHDNARPHTSLVTRQKLLELGWDV--LPHPPYSPDLAPSDYFLFRSLQNSLNGKNFNNDDDVKSYLIQFFANKNQKFYERGIMKLPERWQKVIDQN 336
The following BLAST results are available for this feature:
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
SETMAR4.916e-1038.82SET domain and mariner transposase fusion gene [So... [more]
SETMAR5.063e-1038.82SET domain and mariner transposase fusion gene [So... [more]
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|Q53H47|SETMR_HUMAN2.361e-938.82Histone-lysine N-methyltransferase SETMAR OS=Homo ... [more]
sp|Q7JQ07|MOS1T_DROMA2.549e-726.67Mariner Mos1 transposase OS=Drosophila mauritiana ... [more]
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3L8DAH92.749e-3544.80HTH_48 domain-containing protein OS=Ooceraea biroi... [more]
A0A4W2GJC44.125e-3344.64HTH_48 domain-containing protein OS=Bos indicus x ... [more]
A0A3Q1LQI91.424e-3244.64HTH_48 domain-containing protein OS=Bos taurus OX=... [more]
Q8I8E61.426e-3138.81Ccmar2 transposase OS=Ceratitis capitata OX=7213 P... [more]
A0A068PBT88.142e-3135.94Transposase OS=Heteropoda venatoria OX=152925 GN=m... [more]
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Histone-lysine N-methyltransferase SETMAR vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006498 ID=SMED30006498|Name=Histone-lysine N-methyltransferase SETMAR|organism=Schmidtea mediterranea sexual|type=transcript|length=961bp
ATTATTAATTGCCAAAAAATTTGTGTTTTTCAAAAATCACAAACAAATTA
AATGTCAAAACGAAAGGAGCTTTTATGTCACAGTATGTTGTTTTTCTTTT
AGAAAAAAAAAGTGTTGTCCAGACAAAAAGGAAATCTACGATGATGCCCT
GTATGATTCCTTGTATCGTAAATGGTTTTGACATTTTAATCAAAACAACT
TTGATCTTACCGATGCACCACGTTCTCCAAGAGAGGTTGAAATTCCGGAT
AACGAAATAATGGTGCTAATTGAAGCTGGCCAACATAAAACAACTCGAAA
TATACCTGAAATTCTTGAAATAAATCATTAAACAGTTTCCAGGCAATTGC
GCAACCTTGGAATTGTCAGCAAGGTCGATGTATGGGTACAGCGTGATTTA
ACAGAGAAAAATTTGAAAGAGCGCTTGGTAACGGAAGATGAAAATGGATT
TCGTATACTAAAAAGTTATTTTAGATAATTAAGATATCTTACTCTACGAC
AGGAGAACCTAGTGTCAAAGCCAGATTGCACCCGAAGAAGGTAATGCTAA
GCAATTGGTGGAACTAGGAAGGAATTTTTTTGTATGAGCATATCTGAAAC
GACACCATAAATTCAGATAAATACTGATCCCATCTAAATGAACTGAAGCT
AGCAACCGAACAGAAGTGACCTGCATTAGTCAACCAAAGGTGTATTGTTT
TTTAATATTACAATGCAAAGCAGCACGTGTCTTTGGCCGCTCGGAACAGG
TTATCGCAACTCAATTTTGATGTTTAGTCCATGCATCATACTCTCTCGAT
TTCTACCTATTTAGATCACTTCAAAATAGGTTAGGTTGTAAAAAATTTTG
TTTCTTGAAAGATTTGAAAAATCACCTTATTCATCAAGAAACCCCAGAGG
TTCTATGATTGTGGGATTATGTAACTGCCGGAGACATGTAGAAAGATGAT
AGAACTGAATG
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0008168methyltransferase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0006313transposition, DNA-mediated
GO:0015074DNA integration
GO:0032259methylation