PH and SEC7 domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30006490 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 27Note: Hover over icons to view figure legend
Homology
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Human
Match: PSD3 (pleckstrin and Sec7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19093]) HSP 1 Score: 213.001 bits (541), Expect = 6.975e-59 Identity = 109/248 (43.95%), Postives = 151/248 (60.89%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR F F+L G+TQERER++ HFS RY CN D +D H L CA+++LNT+LH + KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 49 EAAKRLAKRLYQLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTIASQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 294 HSP 2 Score: 81.6481 bits (200), Expect = 3.008e-15 Identity = 55/177 (31.07%), Postives = 90/177 (50.85%), Query Frame = 2
Query: 1961 TVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
V+K T ++ + + +L + + +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 282 AVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEMYVSILK 454
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Human
Match: PSD (pleckstrin and Sec7 domain containing [Source:HGNC Symbol;Acc:HGNC:9507]) HSP 1 Score: 211.46 bits (537), Expect = 3.278e-57 Identity = 108/248 (43.55%), Postives = 155/248 (62.50%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDE-----LVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
D EAA+RLA+RLY DGF+ DVA+HL K NDFS++V E+ FF +GM LD ALR+FL L G+TQERER++ HFS+RY CN + + ED HTL CAL++LNT+LH + K M+ DFI NL+ LNDG +FP + L+ L+ +I+ E ++W +D+E L + + N + IS + + D + + + G +VRK +P RKT GKRGWK ++G L+ + +YL K+
Sbjct: 175 DLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRSLSELADPNPKVIKRISGGSGSGSSPF-LDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKE 421 HSP 2 Score: 84.7297 bits (208), Expect = 4.611e-16 Identity = 51/151 (33.77%), Postives = 82/151 (54.30%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQ----RYKTYSQLLEFEI 2488
I IHHA ATRA DY K+ +VF ++T +LFQ + ++M++WI IN VAA+ S P +S+ +K S +P T Q+ +H+ +L+ + S L+E+ + K+ R + E R +E L+ RY TY+ LL ++
Sbjct: 438 ISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPS-AATRLSQEEQVRTHEA---KLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLRVKL 584
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Human
Match: PSD3 (pleckstrin and Sec7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19093]) HSP 1 Score: 213.386 bits (542), Expect = 3.202e-56 Identity = 109/248 (43.95%), Postives = 151/248 (60.89%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR F F+L G+TQERER++ HFS RY CN D +D H L CA+++LNT+LH + KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 518 EAAKRLAKRLYQLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTIASQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 763 HSP 2 Score: 82.0333 bits (201), Expect = 3.964e-15 Identity = 51/148 (34.46%), Postives = 79/148 (53.38%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
+ +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 780 VSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEMYVSILK 923
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Human
Match: PSD3 (pleckstrin and Sec7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19093]) HSP 1 Score: 213.386 bits (542), Expect = 4.397e-56 Identity = 109/248 (43.95%), Postives = 151/248 (60.89%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR F F+L G+TQERER++ HFS RY CN D +D H L CA+++LNT+LH + KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 583 EAAKRLAKRLYQLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTIASQDGVHCLTCAIMLLNTDLHGHNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 828 HSP 2 Score: 82.4185 bits (202), Expect = 3.700e-15 Identity = 51/148 (34.46%), Postives = 79/148 (53.38%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
+ +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 845 VSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEMYVSILK 988
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Human
Match: PSD3 (pleckstrin and Sec7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19093]) HSP 1 Score: 211.46 bits (537), Expect = 1.780e-55 Identity = 109/249 (43.78%), Postives = 150/249 (60.24%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQS--FPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR F F+L G+TQERER++ HFS RY CN D +D H L CA+++LNT+LH KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 583 EAAKRLAKRLYQLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTIASQDGVHCLTCAIMLLNTDLHGHVNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 829 HSP 2 Score: 82.4185 bits (202), Expect = 3.862e-15 Identity = 51/148 (34.46%), Postives = 79/148 (53.38%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
+ +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 846 VSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEMYVSILK 989
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Celegans
Match: efa-6 (Exchange factor for Arf-6 [Source:UniProtKB/Swiss-Prot;Acc:G5EET6]) HSP 1 Score: 148.288 bits (373), Expect = 1.012e-36 Identity = 85/251 (33.86%), Postives = 140/251 (55.78%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD-HDRSCSQ 1591
+REAA+ +AR LY+ T VA L+++N+FS ++ ++ F S R+D ALR FL R L G++ RER++ FS RY+ CN +++ D HTL CAL++LN++LH + KM++ DFI N+ + G F + L+ LF +I+ D + + N K+ + S + E + ++ SG+++RK+++E G KT FG+R W++ Y RLR L +Y D H ++ S+
Sbjct: 199 EREAAQ-IARNLYELKNCTSTQVADRLNEQNEFSFLILVKYLELFQFSTTRIDAALREFLSRVELRGESSARERLLRVFSARYLECNPAIFDSLDEVHTLTCALLLLNSDLHGPNMGKKMTARDFITNIA--HTGCTFKREMLKTLFQSIK---------DNAISLQNSAKNSTANGSVASTSRRQPQQIYEVDPDSVVEYYSGFLMRKYVRETDGGKTPFGRRSWRMVYARLRGLVLYFDTDEHPKATSR 437 HSP 2 Score: 82.4185 bits (202), Expect = 8.405e-16 Identity = 55/172 (31.98%), Postives = 88/172 (51.16%), Query Frame = 2
Query: 2039 DSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPR-PKITTFG-IRNQLESHQKCVLELEKII----SNLKENPPKK--SDKRNRMEFDESIRFREEELQRYKTYSQLLE--FEIAKLHNMTNLRCM 2524
++ + +HHA A A DY KK VFR++ +G E LFQ +N+KE++ W + IN+VAA S P + + K + +PR P+I I QL +H+ V EL ++I ++ N P++ +D+ + F E +RY TY +L E K + T + M
Sbjct: 442 ENAVSLHHALAEPAPDYKKKSFVFRVRIAHGGEILFQTSNQKELQEWCEKINFVAAAFSS--PTLPLPVTSKPETAPMPRLPRIPCLAPITKQLSTHEARVAELNEMIEIVSQSVSPNQPQQLITDRWVLLSF---------EKRRYSTYINVLRRSLEARKASSATTMNIM 602
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Celegans
Match: efa-6 (Exchange factor for Arf-6 [Source:UniProtKB/Swiss-Prot;Acc:G5EET6]) HSP 1 Score: 149.058 bits (375), Expect = 1.960e-36 Identity = 85/251 (33.86%), Postives = 140/251 (55.78%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD-HDRSCSQ 1591
+REAA+ +AR LY+ T VA L+++N+FS ++ ++ F S R+D ALR FL R L G++ RER++ FS RY+ CN +++ D HTL CAL++LN++LH + KM++ DFI N+ + G F + L+ LF +I+ D + + N K+ + S + E + ++ SG+++RK+++E G KT FG+R W++ Y RLR L +Y D H ++ S+
Sbjct: 383 EREAAQ-IARNLYELKNCTSTQVADRLNEQNEFSFLILVKYLELFQFSTTRIDAALREFLSRVELRGESSARERLLRVFSARYLECNPAIFDSLDEVHTLTCALLLLNSDLHGPNMGKKMTARDFITNIA--HTGCTFKREMLKTLFQSIK---------DNAISLQNSAKNSTANGSVASTSRRQPQQIYEVDPDSVVEYYSGFLMRKYVRETDGGKTPFGRRSWRMVYARLRGLVLYFDTDEHPKATSR 621 HSP 2 Score: 82.8037 bits (203), Expect = 8.776e-16 Identity = 55/169 (32.54%), Postives = 86/169 (50.89%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPR-PKITTFG-IRNQLESHQKCVLELEKII----SNLKENPPKK--SDKRNRMEFDESIRFREEELQRYKTYSQLLE--FEIAKLHNMTNLRCM 2524
+ +HHA A A DY KK VFR++ +G E LFQ +N+KE++ W + IN+VAA S P + + K + +PR P+I I QL +H+ V EL ++I ++ N P++ +D+ + F E +RY TY +L E K + T + M
Sbjct: 629 VSLHHALAEPAPDYKKKSFVFRVRIAHGGEILFQTSNQKELQEWCEKINFVAAAFSS--PTLPLPVTSKPETAPMPRLPRIPCLAPITKQLSTHEARVAELNEMIEIVSQSVSPNQPQQLITDRWVLLSF---------EKRRYSTYINVLRRSLEARKASSATTMNIM 786
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Celegans
Match: efa-6 (Exchange factor for Arf-6 [Source:UniProtKB/Swiss-Prot;Acc:G5EET6]) HSP 1 Score: 149.058 bits (375), Expect = 2.103e-36 Identity = 85/251 (33.86%), Postives = 140/251 (55.78%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD-HDRSCSQ 1591
+REAA+ +AR LY+ T VA L+++N+FS ++ ++ F S R+D ALR FL R L G++ RER++ FS RY+ CN +++ D HTL CAL++LN++LH + KM++ DFI N+ + G F + L+ LF +I+ D + + N K+ + S + E + ++ SG+++RK+++E G KT FG+R W++ Y RLR L +Y D H ++ S+
Sbjct: 381 EREAAQ-IARNLYELKNCTSTQVADRLNEQNEFSFLILVKYLELFQFSTTRIDAALREFLSRVELRGESSARERLLRVFSARYLECNPAIFDSLDEVHTLTCALLLLNSDLHGPNMGKKMTARDFITNIA--HTGCTFKREMLKTLFQSIK---------DNAISLQNSAKNSTANGSVASTSRRQPQQIYEVDPDSVVEYYSGFLMRKYVRETDGGKTPFGRRSWRMVYARLRGLVLYFDTDEHPKATSR 619 HSP 2 Score: 82.8037 bits (203), Expect = 9.624e-16 Identity = 55/169 (32.54%), Postives = 86/169 (50.89%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPR-PKITTFG-IRNQLESHQKCVLELEKII----SNLKENPPKK--SDKRNRMEFDESIRFREEELQRYKTYSQLLE--FEIAKLHNMTNLRCM 2524
+ +HHA A A DY KK VFR++ +G E LFQ +N+KE++ W + IN+VAA S P + + K + +PR P+I I QL +H+ V EL ++I ++ N P++ +D+ + F E +RY TY +L E K + T + M
Sbjct: 627 VSLHHALAEPAPDYKKKSFVFRVRIAHGGEILFQTSNQKELQEWCEKINFVAAAFSS--PTLPLPVTSKPETAPMPRLPRIPCLAPITKQLSTHEARVAELNEMIEIVSQSVSPNQPQQLITDRWVLLSF---------EKRRYSTYINVLRRSLEARKASSATTMNIM 784
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Celegans
Match: efa-6 (Exchange factor for Arf-6 [Source:UniProtKB/Swiss-Prot;Acc:G5EET6]) HSP 1 Score: 148.288 bits (373), Expect = 2.421e-36 Identity = 85/251 (33.86%), Postives = 140/251 (55.78%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD-HDRSCSQ 1591
+REAA+ +AR LY+ T VA L+++N+FS ++ ++ F S R+D ALR FL R L G++ RER++ FS RY+ CN +++ D HTL CAL++LN++LH + KM++ DFI N+ + G F + L+ LF +I+ D + + N K+ + S + E + ++ SG+++RK+++E G KT FG+R W++ Y RLR L +Y D H ++ S+
Sbjct: 330 EREAAQ-IARNLYELKNCTSTQVADRLNEQNEFSFLILVKYLELFQFSTTRIDAALREFLSRVELRGESSARERLLRVFSARYLECNPAIFDSLDEVHTLTCALLLLNSDLHGPNMGKKMTARDFITNIA--HTGCTFKREMLKTLFQSIK---------DNAISLQNSAKNSTANGSVASTSRRQPQQIYEVDPDSVVEYYSGFLMRKYVRETDGGKTPFGRRSWRMVYARLRGLVLYFDTDEHPKATSR 568 HSP 2 Score: 82.4185 bits (202), Expect = 1.040e-15 Identity = 55/169 (32.54%), Postives = 86/169 (50.89%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPR-PKITTFG-IRNQLESHQKCVLELEKII----SNLKENPPKK--SDKRNRMEFDESIRFREEELQRYKTYSQLLE--FEIAKLHNMTNLRCM 2524
+ +HHA A A DY KK VFR++ +G E LFQ +N+KE++ W + IN+VAA S P + + K + +PR P+I I QL +H+ V EL ++I ++ N P++ +D+ + F E +RY TY +L E K + T + M
Sbjct: 576 VSLHHALAEPAPDYKKKSFVFRVRIAHGGEILFQTSNQKELQEWCEKINFVAAAFSS--PTLPLPVTSKPETAPMPRLPRIPCLAPITKQLSTHEARVAELNEMIEIVSQSVSPNQPQQLITDRWVLLSF---------EKRRYSTYINVLRRSLEARKASSATTMNIM 733
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Celegans
Match: agef-1 (Arf-1 Guanine nucleotide Exchange Factor homolog [Source:UniProtKB/TrEMBL;Acc:G5EFH7]) HSP 1 Score: 82.8037 bits (203), Expect = 1.310e-15 Identity = 45/138 (32.61%), Postives = 78/138 (56.52%), Query Frame = 2
Query: 905 TDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCN--GDMYNGEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIR 1309
T V L ++F+ V + +F D S + + ALR+FL +F L G+ Q+ +R+M F+ RY+ CN ++ DA + L ++I+L T+LH+++ KM+ +I + +N+G N P + LE +F I K I+
Sbjct: 561 TQVGDFLGDSDEFNNSVMHAYIDFLDFSSIDILAALRMFLEKFRLPGEAQKIDRLMLKFASRYLDCNPRQGIFASADAAYVLAFSIIMLTTDLHNKTVKNKMTKQGYINMNRGINEGGNIPVELLEAIFEDISKNEIK 698
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Fly
Match: Efa6 (gene:FBgn0051158 transcript:FBtr0113395) HSP 1 Score: 248.825 bits (634), Expect = 2.038e-67 Identity = 118/251 (47.01%), Postives = 169/251 (67.33%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
YH PKA+D +A RLA+RL+ DGFK +DV++HLSK NDFS+ V +E+ F LD ALR FL +F+L+G+TQERER++ HFSKR++ CN +N +DA HTL CA+++LNT+LH Q+ KMS ++F+ NL DLNDGENFP D L+ L+ AI+ +P+ W LD+E G + +++ + + N N D P + + ++ GYV+RK + +KT FGKR WK++Y LRDL +YL+KD
Sbjct: 917 YHYSPKAVDMPSAIRLAKRLHSLDGFKKSDVSRHLSKNNDFSRAVADEYLKHFTFEKKSLDQALREFLQQFSLSGETQERERVLVHFSKRFLDCNPGTFNSQDAVHTLTCAIMLLNTDLHGQNINRKMSCAEFVDNLADLNDGENFPKDVLKSLYQAIKTKPLEWALDEE-AGDLQQQRAN----NSALGNVGLNPFLDPPELATAVEYKKGYVMRKCCYDSSFKKTPFGKRSWKMFYCTLRDLVLYLHKD 1162 HSP 2 Score: 98.9821 bits (245), Expect = 1.681e-20 Identity = 54/148 (36.49%), Postives = 91/148 (61.49%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENP-PKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
I IHHA AT+A DY KK++VFR++T +EYLFQ ++ KE+++W++ INYV A +S P P+ G +K R + K + ++ QL+SH+ + +L++ ++ K+ P P K + ES + + EL+RY+TY +L ++
Sbjct: 1179 IRIHHALATKANDYTKKQHVFRLQTADQAEYLFQTSDSKELQSWVETINYVCAAISAP-PLEGGVGSQKRFQRPLLPSKQSKLMLKEQLDSHEVQLAQLDQELNEHKKGPIPSKGLALQNYKEKES--YLQYELRRYRTYVSILSAKM 1323
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Fly
Match: Efa6 (gene:FBgn0051158 transcript:FBtr0113396) HSP 1 Score: 248.44 bits (633), Expect = 3.300e-67 Identity = 118/251 (47.01%), Postives = 169/251 (67.33%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
YH PKA+D +A RLA+RL+ DGFK +DV++HLSK NDFS+ V +E+ F LD ALR FL +F+L+G+TQERER++ HFSKR++ CN +N +DA HTL CA+++LNT+LH Q+ KMS ++F+ NL DLNDGENFP D L+ L+ AI+ +P+ W LD+E G + +++ + + N N D P + + ++ GYV+RK + +KT FGKR WK++Y LRDL +YL+KD
Sbjct: 1051 YHYSPKAVDMPSAIRLAKRLHSLDGFKKSDVSRHLSKNNDFSRAVADEYLKHFTFEKKSLDQALREFLQQFSLSGETQERERVLVHFSKRFLDCNPGTFNSQDAVHTLTCAIMLLNTDLHGQNINRKMSCAEFVDNLADLNDGENFPKDVLKSLYQAIKTKPLEWALDEE-AGDLQQQRAN----NSALGNVGLNPFLDPPELATAVEYKKGYVMRKCCYDSSFKKTPFGKRSWKMFYCTLRDLVLYLHKD 1296 HSP 2 Score: 98.9821 bits (245), Expect = 1.486e-20 Identity = 54/148 (36.49%), Postives = 91/148 (61.49%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENP-PKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
I IHHA AT+A DY KK++VFR++T +EYLFQ ++ KE+++W++ INYV A +S P P+ G +K R + K + ++ QL+SH+ + +L++ ++ K+ P P K + ES + + EL+RY+TY +L ++
Sbjct: 1313 IRIHHALATKANDYTKKQHVFRLQTADQAEYLFQTSDSKELQSWVETINYVCAAISAP-PLEGGVGSQKRFQRPLLPSKQSKLMLKEQLDSHEVQLAQLDQELNEHKKGPIPSKGLALQNYKEKES--YLQYELRRYRTYVSILSAKM 1457
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Fly
Match: Efa6 (gene:FBgn0051158 transcript:FBtr0334559) HSP 1 Score: 248.825 bits (634), Expect = 3.340e-67 Identity = 118/251 (47.01%), Postives = 169/251 (67.33%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
YH PKA+D +A RLA+RL+ DGFK +DV++HLSK NDFS+ V +E+ F LD ALR FL +F+L+G+TQERER++ HFSKR++ CN +N +DA HTL CA+++LNT+LH Q+ KMS ++F+ NL DLNDGENFP D L+ L+ AI+ +P+ W LD+E G + +++ + + N N D P + + ++ GYV+RK + +KT FGKR WK++Y LRDL +YL+KD
Sbjct: 1131 YHYSPKAVDMPSAIRLAKRLHSLDGFKKSDVSRHLSKNNDFSRAVADEYLKHFTFEKKSLDQALREFLQQFSLSGETQERERVLVHFSKRFLDCNPGTFNSQDAVHTLTCAIMLLNTDLHGQNINRKMSCAEFVDNLADLNDGENFPKDVLKSLYQAIKTKPLEWALDEE-AGDLQQQRAN----NSALGNVGLNPFLDPPELATAVEYKKGYVMRKCCYDSSFKKTPFGKRSWKMFYCTLRDLVLYLHKD 1376 HSP 2 Score: 98.9821 bits (245), Expect = 1.567e-20 Identity = 54/148 (36.49%), Postives = 91/148 (61.49%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENP-PKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
I IHHA AT+A DY KK++VFR++T +EYLFQ ++ KE+++W++ INYV A +S P P+ G +K R + K + ++ QL+SH+ + +L++ ++ K+ P P K + ES + + EL+RY+TY +L ++
Sbjct: 1393 IRIHHALATKANDYTKKQHVFRLQTADQAEYLFQTSDSKELQSWVETINYVCAAISAP-PLEGGVGSQKRFQRPLLPSKQSKLMLKEQLDSHEVQLAQLDQELNEHKKGPIPSKGLALQNYKEKES--YLQYELRRYRTYVSILSAKM 1537
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Fly
Match: Efa6 (gene:FBgn0051158 transcript:FBtr0302187) HSP 1 Score: 248.054 bits (632), Expect = 3.682e-67 Identity = 118/251 (47.01%), Postives = 169/251 (67.33%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
YH PKA+D +A RLA+RL+ DGFK +DV++HLSK NDFS+ V +E+ F LD ALR FL +F+L+G+TQERER++ HFSKR++ CN +N +DA HTL CA+++LNT+LH Q+ KMS ++F+ NL DLNDGENFP D L+ L+ AI+ +P+ W LD+E G + +++ + + N N D P + + ++ GYV+RK + +KT FGKR WK++Y LRDL +YL+KD
Sbjct: 917 YHYSPKAVDMPSAIRLAKRLHSLDGFKKSDVSRHLSKNNDFSRAVADEYLKHFTFEKKSLDQALREFLQQFSLSGETQERERVLVHFSKRFLDCNPGTFNSQDAVHTLTCAIMLLNTDLHGQNINRKMSCAEFVDNLADLNDGENFPKDVLKSLYQAIKTKPLEWALDEE-AGDLQQQRAN----NSALGNVGLNPFLDPPELATAVEYKKGYVMRKCCYDSSFKKTPFGKRSWKMFYCTLRDLVLYLHKD 1162 HSP 2 Score: 98.9821 bits (245), Expect = 1.808e-20 Identity = 54/148 (36.49%), Postives = 91/148 (61.49%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENP-PKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
I IHHA AT+A DY KK++VFR++T +EYLFQ ++ KE+++W++ INYV A +S P P+ G +K R + K + ++ QL+SH+ + +L++ ++ K+ P P K + ES + + EL+RY+TY +L ++
Sbjct: 1179 IRIHHALATKANDYTKKQHVFRLQTADQAEYLFQTSDSKELQSWVETINYVCAAISAP-PLEGGVGSQKRFQRPLLPSKQSKLMLKEQLDSHEVQLAQLDQELNEHKKGPIPSKGLALQNYKEKES--YLQYELRRYRTYVSILSAKM 1323
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Fly
Match: Efa6 (gene:FBgn0051158 transcript:FBtr0334560) HSP 1 Score: 248.44 bits (633), Expect = 3.865e-67 Identity = 118/251 (47.01%), Postives = 169/251 (67.33%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
YH PKA+D +A RLA+RL+ DGFK +DV++HLSK NDFS+ V +E+ F LD ALR FL +F+L+G+TQERER++ HFSKR++ CN +N +DA HTL CA+++LNT+LH Q+ KMS ++F+ NL DLNDGENFP D L+ L+ AI+ +P+ W LD+E G + +++ + + N N D P + + ++ GYV+RK + +KT FGKR WK++Y LRDL +YL+KD
Sbjct: 1051 YHYSPKAVDMPSAIRLAKRLHSLDGFKKSDVSRHLSKNNDFSRAVADEYLKHFTFEKKSLDQALREFLQQFSLSGETQERERVLVHFSKRFLDCNPGTFNSQDAVHTLTCAIMLLNTDLHGQNINRKMSCAEFVDNLADLNDGENFPKDVLKSLYQAIKTKPLEWALDEE-AGDLQQQRAN----NSALGNVGLNPFLDPPELATAVEYKKGYVMRKCCYDSSFKKTPFGKRSWKMFYCTLRDLVLYLHKD 1296 HSP 2 Score: 99.3673 bits (246), Expect = 1.297e-20 Identity = 54/148 (36.49%), Postives = 91/148 (61.49%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENP-PKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
I IHHA AT+A DY KK++VFR++T +EYLFQ ++ KE+++W++ INYV A +S P P+ G +K R + K + ++ QL+SH+ + +L++ ++ K+ P P K + ES + + EL+RY+TY +L ++
Sbjct: 1313 IRIHHALATKANDYTKKQHVFRLQTADQAEYLFQTSDSKELQSWVETINYVCAAISAP-PLEGGVGSQKRFQRPLLPSKQSKLMLKEQLDSHEVQLAQLDQELNEHKKGPIPSKGLALQNYKEKES--YLQYELRRYRTYVSILSAKM 1457
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Zebrafish
Match: psda (pleckstrin and Sec7 domain containing a [Source:ZFIN;Acc:ZDB-GENE-090313-44]) HSP 1 Score: 228.024 bits (580), Expect = 2.283e-64 Identity = 117/254 (46.06%), Postives = 165/254 (64.96%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKS--------DMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDR 1579
D +AAKRLA+RLY DGFK +DVA+HLSK N+FS +V EE+ + F+ SGM +D ALR+FL F L G+TQERER++ HFSKRY+ CN ED+ HTL CAL++LNT+LH + K MS FI NL+ LNDG++FP D L+ L+ +I+ E ++W +D+E L KS D + + I++ N + S+++ + +G++VRK +P G+KT GKRGWK +Y L+ L +YL KD R
Sbjct: 27 DLQAAKRLAKRLYTLDGFKKSDVARHLSKNNEFSHMVAEEYLSHFNFSGMMVDQALRVFLKEFALMGETQERERVLSHFSKRYLQCNPKTIPYEDSVHTLTCALMLLNTDLHGHNVGKRMSCMQFIGNLQGLNDGQDFPKDLLKALYNSIKNEKLQWTIDEE-----ELRKSFSEMDGRKDSASHTMKRISSGGNSLISVAQQSSAQVYKNGFLVRKVHADPDGKKTPRGKRGWKTFYAILKGLILYLQKDEYR 275 HSP 2 Score: 84.3445 bits (207), Expect = 2.780e-16 Identity = 49/148 (33.11%), Postives = 78/148 (52.70%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPP-KKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
+ IHH+ A RA DY K+ NVF ++T +LFQ N ++M++WI IN VAA+ S P I + +K S +P T QL+SH+ + + L+ P +K+ R++ E+ + + + E RY TY+ LL +I
Sbjct: 289 VSIHHSLAMRAADYSKRPNVFYLRTADWRVFLFQAPNAEQMQSWITRINTVAAMFSAPPFPAAIGSQKKFSRPLLPGSN-TKLSQEEQLKSHETRFRTVSAELQELRSTPQDRKTKSRDQEEYKQREEYLDFEKTRYGTYTMLLRTKI 435
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Zebrafish
Match: BX890597.1 (pleckstrin and Sec7 domain containing a [Source:NCBI gene;Acc:570918]) HSP 1 Score: 227.254 bits (578), Expect = 3.785e-64 Identity = 117/254 (46.06%), Postives = 165/254 (64.96%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKS--------DMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDR 1579
D +AAKRLA+RLY DGFK +DVA+HLSK N+FS +V EE+ + F+ SGM +D ALR+FL F L G+TQERER++ HFSKRY+ CN ED+ HTL CAL++LNT+LH + K MS FI NL+ LNDG++FP D L+ L+ +I+ E ++W +D+E L KS D + + I++ N + S+++ + +G++VRK +P G+KT GKRGWK +Y L+ L +YL KD R
Sbjct: 19 DLQAAKRLAKRLYTLDGFKKSDVARHLSKNNEFSHMVAEEYLSHFNFSGMMVDQALRVFLKEFALMGETQERERVLSHFSKRYLQCNPKTIPYEDSVHTLTCALMLLNTDLHGHNVGKRMSCMQFIGNLQGLNDGQDFPKDLLKALYNSIKNEKLQWTIDEE-----ELRKSFSEMDGRKDSASHTMKRISSGGNSLISVAQQSSAQVYKNGFLVRKVHADPDGKKTPRGKRGWKTFYAILKGLILYLQKDEYR 267 HSP 2 Score: 83.9593 bits (206), Expect = 3.523e-16 Identity = 49/148 (33.11%), Postives = 78/148 (52.70%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPP-KKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
+ IHH+ A RA DY K+ NVF ++T +LFQ N ++M++WI IN VAA+ S P I + +K S +P T QL+SH+ + + L+ P +K+ R++ E+ + + + E RY TY+ LL +I
Sbjct: 281 VSIHHSLAMRAADYSKRPNVFYLRTADWRVFLFQAPNAEQMQSWITRINTVAAMFSAPPFPAAIGSQKKFSRPLLPGSN-TKLSQEEQLKSHETRFRTVSAELQELRSTPQDRKTKSRDQEEYKQREEYLDFEKTRYGTYTMLLRTKI 427
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Zebrafish
Match: psda (pleckstrin and Sec7 domain containing a [Source:ZFIN;Acc:ZDB-GENE-090313-44]) HSP 1 Score: 227.254 bits (578), Expect = 6.738e-64 Identity = 117/254 (46.06%), Postives = 165/254 (64.96%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKS--------DMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDR 1579
D +AAKRLA+RLY DGFK +DVA+HLSK N+FS +V EE+ + F+ SGM +D ALR+FL F L G+TQERER++ HFSKRY+ CN ED+ HTL CAL++LNT+LH + K MS FI NL+ LNDG++FP D L+ L+ +I+ E ++W +D+E L KS D + + I++ N + S+++ + +G++VRK +P G+KT GKRGWK +Y L+ L +YL KD R
Sbjct: 50 DLQAAKRLAKRLYTLDGFKKSDVARHLSKNNEFSHMVAEEYLSHFNFSGMMVDQALRVFLKEFALMGETQERERVLSHFSKRYLQCNPKTIPYEDSVHTLTCALMLLNTDLHGHNVGKRMSCMQFIGNLQGLNDGQDFPKDLLKALYNSIKNEKLQWTIDEE-----ELRKSFSEMDGRKDSASHTMKRISSGGNSLISVAQQSSAQVYKNGFLVRKVHADPDGKKTPRGKRGWKTFYAILKGLILYLQKDEYR 298 HSP 2 Score: 84.3445 bits (207), Expect = 2.538e-16 Identity = 49/148 (33.11%), Postives = 78/148 (52.70%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPP-KKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
+ IHH+ A RA DY K+ NVF ++T +LFQ N ++M++WI IN VAA+ S P I + +K S +P T QL+SH+ + + L+ P +K+ R++ E+ + + + E RY TY+ LL +I
Sbjct: 312 VSIHHSLAMRAADYSKRPNVFYLRTADWRVFLFQAPNAEQMQSWITRINTVAAMFSAPPFPAAIGSQKKFSRPLLPGSN-TKLSQEEQLKSHETRFRTVSAELQELRSTPQDRKTKSRDQEEYKQREEYLDFEKTRYGTYTMLLRTKI 458
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Zebrafish
Match: psda (pleckstrin and Sec7 domain containing a [Source:ZFIN;Acc:ZDB-GENE-090313-44]) HSP 1 Score: 227.254 bits (578), Expect = 8.624e-64 Identity = 117/254 (46.06%), Postives = 165/254 (64.96%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKS--------DMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDR 1579
D +AAKRLA+RLY DGFK +DVA+HLSK N+FS +V EE+ + F+ SGM +D ALR+FL F L G+TQERER++ HFSKRY+ CN ED+ HTL CAL++LNT+LH + K MS FI NL+ LNDG++FP D L+ L+ +I+ E ++W +D+E L KS D + + I++ N + S+++ + +G++VRK +P G+KT GKRGWK +Y L+ L +YL KD R
Sbjct: 60 DLQAAKRLAKRLYTLDGFKKSDVARHLSKNNEFSHMVAEEYLSHFNFSGMMVDQALRVFLKEFALMGETQERERVLSHFSKRYLQCNPKTIPYEDSVHTLTCALMLLNTDLHGHNVGKRMSCMQFIGNLQGLNDGQDFPKDLLKALYNSIKNEKLQWTIDEE-----ELRKSFSEMDGRKDSASHTMKRISSGGNSLISVAQQSSAQVYKNGFLVRKVHADPDGKKTPRGKRGWKTFYAILKGLILYLQKDEYR 308 HSP 2 Score: 84.7297 bits (208), Expect = 2.250e-16 Identity = 49/148 (33.11%), Postives = 78/148 (52.70%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPP-KKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
+ IHH+ A RA DY K+ NVF ++T +LFQ N ++M++WI IN VAA+ S P I + +K S +P T QL+SH+ + + L+ P +K+ R++ E+ + + + E RY TY+ LL +I
Sbjct: 322 VSIHHSLAMRAADYSKRPNVFYLRTADWRVFLFQAPNAEQMQSWITRINTVAAMFSAPPFPAAIGSQKKFSRPLLPGSN-TKLSQEEQLKSHETRFRTVSAELQELRSTPQDRKTKSRDQEEYKQREEYLDFEKTRYGTYTMLLRTKI 468
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Zebrafish
Match: psd3l (pleckstrin and Sec7 domain containing 3, like [Source:ZFIN;Acc:ZDB-GENE-030131-8195]) HSP 1 Score: 212.231 bits (539), Expect = 3.971e-56 Identity = 108/247 (43.72%), Postives = 156/247 (63.16%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLD-DEL-VGIVNLNKSDMMDISKQM--INTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
D+EAA+RLARRLY +GF+ +DVAKHL K NDFS++V EE+ FF+ + LD +LR FL F+L G+TQERER++ HFS RY CN + +D H L CAL++LNT+LH + KM+ +FI NL LN G++FP + L+ L+ +I+ E + W +D DEL + L + SK + I++ N D D N+ + +G++ RK + G+KT GKRGWK +Y L+ + +YL KD
Sbjct: 501 DQEAARRLARRLYHLEGFRRSDVAKHLGKNNDFSKMVAEEYLTFFEFTDQTLDQSLRCFLKAFSLMGETQERERVLIHFSNRYYQCNPTIITAQDGVHCLTCALMLLNTDLHGPNIGKKMTCQEFINNLDGLNGGQDFPRELLKSLYNSIKNEKLEWAVDGDELKKSLSELADKNHHSHSKSISRISSGSNPFLDIAHDPNAAVYKTGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGMILYLQKD 747 HSP 2 Score: 83.9593 bits (206), Expect = 7.307e-16 Identity = 54/154 (35.06%), Postives = 81/154 (52.60%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQ----RYKTYSQLLEFEIAKL 2497
I +HHA A +A+DY KK NV ++KT +LFQ + +EME+WI IN VAA+ S P I + +K S +P T QL+SH+ + + ++ + PP K K E DE R +E L+ RY+ Y +LL+ + +L
Sbjct: 764 ISVHHALAIKAMDYEKKPNVLKLKTADWRVFLFQAQSPEEMESWIRIINSVAAMFSAPSFPAAIGSQKKFSRPLLP-ATTTRMSQEEQLKSHEAKLKHVSTELAEHRSYPPDK--KVKAKEIDE-YRLKEHYLEFEENRYEMYVKLLKEGVKEL 913
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Xenopus
Match: PSD3 (pleckstrin and Sec7 domain containing 3 [Source:NCBI gene;Acc:100127548]) HSP 1 Score: 207.994 bits (528), Expect = 9.432e-58 Identity = 108/250 (43.20%), Postives = 156/250 (62.40%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMD-----ISKQMIN--TNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
+++AAKRLA+RLY DGFK +DVAKHL K NDFS+IV EE+ FFD +G+ LD +LR+F F+L G+TQERER++ HFS RY CN + + D H L CA+++LNT+LH + KMS +FI NL+ +N+G +FP L+ L+ +I+ E + W DD V + + SD D + +N + N + P D N+ + +G++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 53 NKQAAKRLAKRLYHLDGFKRSDVAKHLGKNNDFSKIVAEEYLKFFDFTGLTLDQSLRIFFKAFSLIGETQERERVLVHFSNRYFLCNPNSISSIDGVHCLTCAIMLLNTDLHGHNIGKKMSCQEFIANLQGVNEGRDFPRVLLKALYNSIKNEKLEWAADD--VDAMKKSPSDNADEKPNGTQSKSVNRIGSSNPFLEIPHDPNAAVYKTGFLARKIHADMDGKKTPRGKRGWKTFYAILKGTVLYLQKD 300 HSP 2 Score: 77.7962 bits (190), Expect = 3.057e-14 Identity = 50/176 (28.41%), Postives = 82/176 (46.59%), Query Frame = 2
Query: 1961 TVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
++K T ++ + + +L + + IHHA A +A DY K+ NV ++KT +LFQ + +EME WI IN VAA+ S P I + +K S +P T QL SH+ + ++ ++ + PP K + + +E+ YK LEFE+
Sbjct: 288 AILKGTVLYLQKDEYKPEKALSEDDLKNAVSIHHALALKATDYEKRPNVLKLKTADWRVFLFQAQSTEEMELWISKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLTKDEQLRSHETKLKQISTELAEHRSYPPDK-------------KVKAKEIDEYKLKDHYLEFEV 449
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Xenopus
Match: PSD3 (pleckstrin and Sec7 domain containing 3 [Source:NCBI gene;Acc:100127548]) HSP 1 Score: 203.756 bits (517), Expect = 3.925e-55 Identity = 102/243 (41.98%), Postives = 150/243 (61.73%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
+++AAKRLA+RLY DGFK +DVAKHL K NDFS+IV EE+ FFD +G+ LD +LR+F F+L G+TQERER++ HFS RY CN + + D H L CA+++LNT+LH + KMS +FI NL+ +N+G +FP L+ L+ +I+ E + W N + +++ + F + P D N+ + +G++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 117 NKQAAKRLAKRLYHLDGFKRSDVAKHLGKNNDFSKIVAEEYLKFFDFTGLTLDQSLRIFFKAFSLIGETQERERVLVHFSNRYFLCNPNSISSIDGVHCLTCAIMLLNTDLHGHNIGKKMSCQEFIANLQGVNEGRDFPRVLLKALYNSIKNEKLEWAKSPSDNADEKPNGTQSKSVNRIGSSNPF---LEIPHDPNAAVYKTGFLARKIHADMDGKKTPRGKRGWKTFYAILKGTVLYLQKD 356 HSP 2 Score: 78.9518 bits (193), Expect = 2.443e-14 Identity = 48/145 (33.10%), Postives = 74/145 (51.03%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRM-EFDESIRFREEELQRYKTYSQLLE 2479
+ IHHA A +A DY K+ NV ++KT +LFQ + +EME WI IN VAA+ S P I + +K S +P T QL SH+ + ++ ++ + PP K K + E+ + E E RY+ Y ++L+
Sbjct: 373 VSIHHALALKATDYEKRPNVLKLKTADWRVFLFQAQSTEEMELWISKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLTKDEQLRSHETKLKQISTELAEHRSYPPDKKVKAKEIDEYKLKDHYLEFEKTRYEVYVKILK 516
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Xenopus
Match: PSD3 (pleckstrin and Sec7 domain containing 3 [Source:NCBI gene;Acc:100127548]) HSP 1 Score: 191.43 bits (485), Expect = 8.852e-52 Identity = 105/250 (42.00%), Postives = 151/250 (60.40%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMD-----ISKQMIN--TNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
+++AAKRLA+RLY DGFK +DVAKHL K NDFS+IV EE+ FFD +G+ LD +LR+F F+L G+TQERER++ HFS RY CN + + D H L CA+++LNT+LH + KMS +FI NL+ +N+G +FP L++L +DD V + + SD D + +N + N + P D N+ + +G++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 22 NKQAAKRLAKRLYHLDGFKRSDVAKHLGKNNDFSKIVAEEYLKFFDFTGLTLDQSLRIFFKAFSLIGETQERERVLVHFSNRYFLCNPNSISSIDGVHCLTCAIMLLNTDLHGHNIGKKMSCQEFIANLQGVNEGRDFPR-VLKDLLQI---------MDD--VDAMKKSPSDNADEKPNGTQSKSVNRIGSSNPFLEIPHDPNAAVYKTGFLARKIHADMDGKKTPRGKRGWKTFYAILKGTVLYLQKD 259 HSP 2 Score: 78.5666 bits (192), Expect = 1.959e-14 Identity = 48/145 (33.10%), Postives = 74/145 (51.03%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRM-EFDESIRFREEELQRYKTYSQLLE 2479
+ IHHA A +A DY K+ NV ++KT +LFQ + +EME WI IN VAA+ S P I + +K S +P T QL SH+ + ++ ++ + PP K K + E+ + E E RY+ Y ++L+
Sbjct: 276 VSIHHALALKATDYEKRPNVLKLKTADWRVFLFQAQSTEEMELWISKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLTKDEQLRSHETKLKQISTELAEHRSYPPDKKVKAKEIDEYKLKDHYLEFEKTRYEVYVKILK 419
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Xenopus
Match: PSD3 (pleckstrin and Sec7 domain containing 3 [Source:NCBI gene;Acc:100127548]) HSP 1 Score: 190.274 bits (482), Expect = 4.037e-51 Identity = 105/250 (42.00%), Postives = 151/250 (60.40%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMD-----ISKQMIN--TNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
+++AAKRLA+RLY DGFK +DVAKHL K NDFS+IV EE+ FFD +G+ LD +LR+F F+L G+TQERER++ HFS RY CN + + D H L CA+++LNT+LH + KMS +FI NL+ +N+G +FP L++L +DD V + + SD D + +N + N + P D N+ + +G++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 52 NKQAAKRLAKRLYHLDGFKRSDVAKHLGKNNDFSKIVAEEYLKFFDFTGLTLDQSLRIFFKAFSLIGETQERERVLVHFSNRYFLCNPNSISSIDGVHCLTCAIMLLNTDLHGHNIGKKMSCQEFIANLQGVNEGRDFPR-VLKDLLQI---------MDD--VDAMKKSPSDNADEKPNGTQSKSVNRIGSSNPFLEIPHDPNAAVYKTGFLARKIHADMDGKKTPRGKRGWKTFYAILKGTVLYLQKD 289 HSP 2 Score: 78.9518 bits (193), Expect = 1.930e-14 Identity = 48/145 (33.10%), Postives = 74/145 (51.03%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRM-EFDESIRFREEELQRYKTYSQLLE 2479
+ IHHA A +A DY K+ NV ++KT +LFQ + +EME WI IN VAA+ S P I + +K S +P T QL SH+ + ++ ++ + PP K K + E+ + E E RY+ Y ++L+
Sbjct: 306 VSIHHALALKATDYEKRPNVLKLKTADWRVFLFQAQSTEEMELWISKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLTKDEQLRSHETKLKQISTELAEHRSYPPDKKVKAKEIDEYKLKDHYLEFEKTRYEVYVKILK 449
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Xenopus
Match: PSD3 (pleckstrin and Sec7 domain containing 3 [Source:NCBI gene;Acc:100127548]) HSP 1 Score: 190.66 bits (483), Expect = 2.194e-50 Identity = 105/250 (42.00%), Postives = 151/250 (60.40%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMD-----ISKQMIN--TNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
+++AAKRLA+RLY DGFK +DVAKHL K NDFS+IV EE+ FFD +G+ LD +LR+F F+L G+TQERER++ HFS RY CN + + D H L CA+++LNT+LH + KMS +FI NL+ +N+G +FP L++L +DD V + + SD D + +N + N + P D N+ + +G++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 171 NKQAAKRLAKRLYHLDGFKRSDVAKHLGKNNDFSKIVAEEYLKFFDFTGLTLDQSLRIFFKAFSLIGETQERERVLVHFSNRYFLCNPNSISSIDGVHCLTCAIMLLNTDLHGHNIGKKMSCQEFIANLQGVNEGRDFPR-VLKDLLQI---------MDD--VDAMKKSPSDNADEKPNGTQSKSVNRIGSSNPFLEIPHDPNAAVYKTGFLARKIHADMDGKKTPRGKRGWKTFYAILKGTVLYLQKD 408 HSP 2 Score: 79.337 bits (194), Expect = 1.690e-14 Identity = 48/145 (33.10%), Postives = 74/145 (51.03%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRM-EFDESIRFREEELQRYKTYSQLLE 2479
+ IHHA A +A DY K+ NV ++KT +LFQ + +EME WI IN VAA+ S P I + +K S +P T QL SH+ + ++ ++ + PP K K + E+ + E E RY+ Y ++L+
Sbjct: 425 VSIHHALALKATDYEKRPNVLKLKTADWRVFLFQAQSTEEMELWISKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLTKDEQLRSHETKLKQISTELAEHRSYPPDKKVKAKEIDEYKLKDHYLEFEKTRYEVYVKILK 568
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Mouse
Match: Psd3 (pleckstrin and Sec7 domain containing 3 [Source:MGI Symbol;Acc:MGI:1918215]) HSP 1 Score: 215.698 bits (548), Expect = 6.131e-60 Identity = 111/248 (44.76%), Postives = 153/248 (61.69%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR FL F+L G+TQERER++ HFS RY SCN D +D H L CA+++LNT+LH + KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 54 EAAKRLAKRLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQERERVLIHFSNRYFSCNPDTITSKDGVHCLTCAMMLLNTDLHGHNIGKKMTCQEFITNLQGVNEGGDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSEGTDEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 299 HSP 2 Score: 82.4185 bits (202), Expect = 1.181e-15 Identity = 56/176 (31.82%), Postives = 90/176 (51.14%), Query Frame = 2
Query: 1964 VIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
V+K T ++ + + SL + + +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 288 VLKGTVLYLQKDEYKPEKSLSDEDLKNAVSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEIYVSVLK 459
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Mouse
Match: Psd3 (pleckstrin and Sec7 domain containing 3 [Source:MGI Symbol;Acc:MGI:1918215]) HSP 1 Score: 216.853 bits (551), Expect = 2.576e-57 Identity = 111/248 (44.76%), Postives = 153/248 (61.69%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR FL F+L G+TQERER++ HFS RY SCN D +D H L CA+++LNT+LH + KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 571 EAAKRLAKRLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQERERVLIHFSNRYFSCNPDTITSKDGVHCLTCAMMLLNTDLHGHNIGKKMTCQEFITNLQGVNEGGDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSEGTDEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 816 HSP 2 Score: 82.4185 bits (202), Expect = 2.223e-15 Identity = 51/148 (34.46%), Postives = 79/148 (53.38%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
+ +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 833 VSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEIYVSVLK 976
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Mouse
Match: Psd3 (pleckstrin and Sec7 domain containing 3 [Source:MGI Symbol;Acc:MGI:1918215]) HSP 1 Score: 216.853 bits (551), Expect = 5.141e-57 Identity = 111/248 (44.76%), Postives = 153/248 (61.69%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR FL F+L G+TQERER++ HFS RY SCN D +D H L CA+++LNT+LH + KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 825 EAAKRLAKRLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQERERVLIHFSNRYFSCNPDTITSKDGVHCLTCAMMLLNTDLHGHNIGKKMTCQEFITNLQGVNEGGDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSEGTDEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 1070 HSP 2 Score: 83.5741 bits (205), Expect = 1.315e-15 Identity = 51/148 (34.46%), Postives = 79/148 (53.38%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
+ +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 1087 VSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPA-TTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEIYVSVLK 1230
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Mouse
Match: Psd3 (pleckstrin and Sec7 domain containing 3 [Source:MGI Symbol;Acc:MGI:1918215]) HSP 1 Score: 214.542 bits (545), Expect = 1.095e-56 Identity = 111/249 (44.58%), Postives = 152/249 (61.04%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQS--FPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR FL F+L G+TQERER++ HFS RY SCN D +D H L CA+++LNT+LH KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 539 EAAKRLAKRLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQERERVLIHFSNRYFSCNPDTITSKDGVHCLTCAMMLLNTDLHGHVNIGKKMTCQEFITNLQGVNEGGDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSEGTDEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 785 HSP 2 Score: 82.8037 bits (203), Expect = 1.739e-15 Identity = 56/177 (31.64%), Postives = 90/177 (50.85%), Query Frame = 2
Query: 1961 TVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
V+K T ++ + + SL + + +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 773 AVLKGTVLYLQKDEYKPEKSLSDEDLKNAVSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEIYVSVLK 945
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Mouse
Match: Psd3 (pleckstrin and Sec7 domain containing 3 [Source:MGI Symbol;Acc:MGI:1918215]) HSP 1 Score: 214.542 bits (545), Expect = 1.095e-56 Identity = 111/249 (44.58%), Postives = 152/249 (61.04%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQS--FPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR FL F+L G+TQERER++ HFS RY SCN D +D H L CA+++LNT+LH KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 539 EAAKRLAKRLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQERERVLIHFSNRYFSCNPDTITSKDGVHCLTCAMMLLNTDLHGHVNIGKKMTCQEFITNLQGVNEGGDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSEGTDEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 785 HSP 2 Score: 82.8037 bits (203), Expect = 1.739e-15 Identity = 56/177 (31.64%), Postives = 90/177 (50.85%), Query Frame = 2
Query: 1961 TVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
V+K T ++ + + SL + + +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 773 AVLKGTVLYLQKDEYKPEKSLSDEDLKNAVSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEIYVSVLK 945
BLAST of PH and SEC7 domain-containing protein vs. UniProt/SwissProt
Match: sp|E1JIT7|PSD_DROME (PH and SEC7 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Efa6 PE=1 SV=2) HSP 1 Score: 248.825 bits (634), Expect = 3.348e-66 Identity = 118/251 (47.01%), Postives = 169/251 (67.33%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
YH PKA+D +A RLA+RL+ DGFK +DV++HLSK NDFS+ V +E+ F LD ALR FL +F+L+G+TQERER++ HFSKR++ CN +N +DA HTL CA+++LNT+LH Q+ KMS ++F+ NL DLNDGENFP D L+ L+ AI+ +P+ W LD+E G + +++ + + N N D P + + ++ GYV+RK + +KT FGKR WK++Y LRDL +YL+KD
Sbjct: 1131 YHYSPKAVDMPSAIRLAKRLHSLDGFKKSDVSRHLSKNNDFSRAVADEYLKHFTFEKKSLDQALREFLQQFSLSGETQERERVLVHFSKRFLDCNPGTFNSQDAVHTLTCAIMLLNTDLHGQNINRKMSCAEFVDNLADLNDGENFPKDVLKSLYQAIKTKPLEWALDEE-AGDLQQQRAN----NSALGNVGLNPFLDPPELATAVEYKKGYVMRKCCYDSSFKKTPFGKRSWKMFYCTLRDLVLYLHKD 1376 HSP 2 Score: 98.9821 bits (245), Expect = 1.571e-19 Identity = 54/148 (36.49%), Postives = 91/148 (61.49%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENP-PKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEI 2488
I IHHA AT+A DY KK++VFR++T +EYLFQ ++ KE+++W++ INYV A +S P P+ G +K R + K + ++ QL+SH+ + +L++ ++ K+ P P K + ES + + EL+RY+TY +L ++
Sbjct: 1393 IRIHHALATKANDYTKKQHVFRLQTADQAEYLFQTSDSKELQSWVETINYVCAAISAP-PLEGGVGSQKRFQRPLLPSKQSKLMLKEQLDSHEVQLAQLDQELNEHKKGPIPSKGLALQNYKEKES--YLQYELRRYRTYVSILSAKM 1537
BLAST of PH and SEC7 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9ESQ7|PSD1_RAT (PH and SEC7 domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Psd PE=1 SV=1) HSP 1 Score: 211.846 bits (538), Expect = 1.112e-56 Identity = 107/250 (42.80%), Postives = 156/250 (62.40%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIG-------YDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
D EAA+RLA+RLY DGF+ DVA+HL K NDFS++V E+ FF +GM LD ALR+FL L G+TQERER++ HFS+RY CN + + ED HTL CAL++LNT+LH + K M+ DFI NL+ LNDG +FP + L+ L+ +I+ E ++W +D+E + + S++ D + ++I D + + + G +VRK +P RKT GKRGWK ++G L+ + +YL K+
Sbjct: 179 DLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEE---ELRRSLSELADPNPKVIKRVSGGSGSSSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKE 425 HSP 2 Score: 82.8037 bits (203), Expect = 9.249e-15 Identity = 55/165 (33.33%), Postives = 87/165 (52.73%), Query Frame = 2
Query: 2012 QPSLILPPAD--SEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQ----RYKTYSQLLEFEI 2488
QP L A+ + I IHHA ATRA DY K+ +VF ++T +LFQ + ++M++WI IN VAA+ S P +S+ +K S +P T Q+ +H+ +L+ + S L+E+ K+ R + E R +E L+ RY TY+ LL ++
Sbjct: 428 QPGKALSEAELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPS-AATRLSQEEQVRTHEA---KLKAMASELREHRAAHLGKKARGKEAEEQRQKETYLEFEKSRYGTYAALLRVKM 588
BLAST of PH and SEC7 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q2PFD7|PSD3_MOUSE (PH and SEC7 domain-containing protein 3 OS=Mus musculus OX=10090 GN=Psd3 PE=1 SV=2) HSP 1 Score: 214.927 bits (546), Expect = 7.121e-56 Identity = 111/249 (44.58%), Postives = 152/249 (61.04%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQS--FPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR FL F+L G+TQERER++ HFS RY SCN D +D H L CA+++LNT+LH KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 572 EAAKRLAKRLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQERERVLIHFSNRYFSCNPDTITSKDGVHCLTCAMMLLNTDLHGHVNIGKKMTCQEFITNLQGVNEGGDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSEGTDEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 818 HSP 2 Score: 82.4185 bits (202), Expect = 1.624e-14 Identity = 51/148 (34.46%), Postives = 79/148 (53.38%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
+ +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 835 VSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEIYVSVLK 978
BLAST of PH and SEC7 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NYI0|PSD3_HUMAN (PH and SEC7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=PSD3 PE=1 SV=2) HSP 1 Score: 211.46 bits (537), Expect = 8.547e-55 Identity = 109/249 (43.78%), Postives = 150/249 (60.24%), Query Frame = 2
Query: 851 EAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQS--FPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIV-------NLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
EAAKRLA+RLY D FK +DVAKHL K N+FS++V EE+ FFD +GM LD +LR F F+L G+TQERER++ HFS RY CN D +D H L CA+++LNT+LH KM+ +FI NL+ +N+G +F D L+ L+ +I+ E + W +DDE N + IS+ I + N D P D N+ + SG++ RK + G+KT GKRGWK +Y L+ +YL KD
Sbjct: 583 EAAKRLAKRLYQLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTIASQDGVHCLTCAIMLLNTDLHGHVNIGKKMTCQEFIANLQGVNEGVDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISR--IGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKD 829 HSP 2 Score: 82.4185 bits (202), Expect = 1.855e-14 Identity = 51/148 (34.46%), Postives = 79/148 (53.38%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN----PPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLE 2479
+ +HHA A++A DY KK NVF++KT LFQ + +EM+ WI+ IN VAA+ S P I + +K S +P T QL+SH+ +L++I + L E+ P KK ++ E+ + E E RY+ Y +L+
Sbjct: 846 VSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLP-ATTTKLSQEEQLKSHES---KLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEMYVSILK 989
BLAST of PH and SEC7 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5DTT2|PSD1_MOUSE (PH and SEC7 domain-containing protein 1 OS=Mus musculus OX=10090 GN=Psd PE=1 SV=2) HSP 1 Score: 211.46 bits (537), Expect = 9.033e-55 Identity = 107/250 (42.80%), Postives = 156/250 (62.40%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIG-------YDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
D EAA+RLA+RLY DGF+ DVA+HL K NDFS++V E+ FF +GM LD ALR+FL L G+TQERER++ HFS+RY CN + + ED HTL CAL++LNT+LH + K M+ DFI NL+ LNDG +FP + L+ L+ +I+ E ++W +D+E + + S++ D + ++I D + + + G +VRK +P RKT GKRGWK ++G L+ + +YL K+
Sbjct: 554 DLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEE---ELRRSLSELADPNPKVIKRVSGGSGSSSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKE 800 HSP 2 Score: 82.8037 bits (203), Expect = 1.316e-14 Identity = 50/151 (33.11%), Postives = 81/151 (53.64%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQ----RYKTYSQLLEFEI 2488
I IHHA ATRA DY K+ +VF ++T +LFQ + ++M++WI IN VAA+ S P +S+ +K S +P T Q+ +H+ +L+ + S L+E+ K+ R + + R +E L+ RY TY+ LL ++
Sbjct: 817 ISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPS-AATRLSQEEQVRTHEA---KLKAMASELREHRAAHLGKKARGKEADEQRQKEAYLEFEKSRYGTYAALLRVKM 963
BLAST of PH and SEC7 domain-containing protein vs. TrEMBL
Match: A0A1S3INW2 (PH and SEC7 domain-containing protein 2 isoform X3 OS=Lingula unguis OX=7574 GN=LOC106165942 PE=4 SV=1) HSP 1 Score: 280.411 bits (716), Expect = 9.695e-76 Identity = 128/251 (51.00%), Postives = 175/251 (69.72%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
Y QP K D +A RLA+RLYD +GFK DVAKHL K+NDFSQ+V EE+ FFD G+ LDVALR FL +F+LTG+TQERER++ HF++RY+ CN D +N EDACHTL CA+++LNT+LH Q+ +M+ +FI NL +LNDGENFP D L+ L+ +I+ P+ W LD+E +++D++ + +N N D P S + ++ GYV+RK EP G+KT GKRGWK+YY LRD+ +Y +KD
Sbjct: 476 YFQPTKNADYPSAYRLAKRLYDLEGFKKADVAKHLGKKNDFSQLVAEEYLKFFDFVGIPLDVALRQFLQQFSLTGETQERERVLAHFTRRYMECNPDSFNSEDACHTLTCAIMLLNTDLHGQNIGRRMTCGEFIDNLAELNDGENFPRDVLKTLYLSIKSRPLEWALDEEGEAT---SETDLLLEESRRVNLGHNPFLDVPDPSQATEYKRGYVMRKCCTEPDGKKTPLGKRGWKMYYATLRDMVLYFHKD 723 HSP 2 Score: 108.227 bits (269), Expect = 5.539e-20 Identity = 62/180 (34.44%), Postives = 105/180 (58.33%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDK-RNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNM-TNLRCMSGNDVPFFCQ-PYHSISGI 2578
+ IHH+ AT+AVDY KK++V R++T + YL Q ++ E++ WID IN+VAA LS P G+ + +K +P T + QL+ H+ V+EL++ + K PP K K R E++E ++ EL+R++TY+ LL+ ++A + ++L M+ ++ Q P HS+S +
Sbjct: 740 VRIHHSLATKAVDYTKKQHVLRLRTAEWAVYLLQSSDPTELQGWIDTINFVAASLSAPPLPGGVGSQKKFQRPLLPS-SYTRLNLTQQLQHHESKVVELQESLEEHKRYPPSKGAKERIIREYEEKEQYLHFELERFQTYAHLLKSKMASFPELESSLVDMAIGEMEEPTQSPSHSLSPL 918
BLAST of PH and SEC7 domain-containing protein vs. TrEMBL
Match: A0A1S3IPC6 (PH and SEC7 domain-containing protein 1 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106165942 PE=4 SV=1) HSP 1 Score: 280.026 bits (715), Expect = 1.451e-75 Identity = 128/251 (51.00%), Postives = 175/251 (69.72%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
Y QP K D +A RLA+RLYD +GFK DVAKHL K+NDFSQ+V EE+ FFD G+ LDVALR FL +F+LTG+TQERER++ HF++RY+ CN D +N EDACHTL CA+++LNT+LH Q+ +M+ +FI NL +LNDGENFP D L+ L+ +I+ P+ W LD+E +++D++ + +N N D P S + ++ GYV+RK EP G+KT GKRGWK+YY LRD+ +Y +KD
Sbjct: 476 YFQPTKNADYPSAYRLAKRLYDLEGFKKADVAKHLGKKNDFSQLVAEEYLKFFDFVGIPLDVALRQFLQQFSLTGETQERERVLAHFTRRYMECNPDSFNSEDACHTLTCAIMLLNTDLHGQNIGRRMTCGEFIDNLAELNDGENFPRDVLKTLYLSIKSRPLEWALDEEGEAT---SETDLLLEESRRVNLGHNPFLDVPDPSQATEYKRGYVMRKCCTEPDGKKTPLGKRGWKMYYATLRDMVLYFHKD 723 HSP 2 Score: 108.227 bits (269), Expect = 5.931e-20 Identity = 62/180 (34.44%), Postives = 105/180 (58.33%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDK-RNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNM-TNLRCMSGNDVPFFCQ-PYHSISGI 2578
+ IHH+ AT+AVDY KK++V R++T + YL Q ++ E++ WID IN+VAA LS P G+ + +K +P T + QL+ H+ V+EL++ + K PP K K R E++E ++ EL+R++TY+ LL+ ++A + ++L M+ ++ Q P HS+S +
Sbjct: 740 VRIHHSLATKAVDYTKKQHVLRLRTAEWAVYLLQSSDPTELQGWIDTINFVAASLSAPPLPGGVGSQKKFQRPLLPS-SYTRLNLTQQLQHHESKVVELQESLEEHKRYPPSKGAKERIIREYEEKEQYLHFELERFQTYAHLLKSKMASFPELESSLVDMAIGEMEEPTQSPSHSLSPL 918
BLAST of PH and SEC7 domain-containing protein vs. TrEMBL
Match: A0A1S3IND9 (PH and SEC7 domain-containing protein 1 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106165942 PE=4 SV=1) HSP 1 Score: 280.026 bits (715), Expect = 1.645e-75 Identity = 128/251 (51.00%), Postives = 175/251 (69.72%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
Y QP K D +A RLA+RLYD +GFK DVAKHL K+NDFSQ+V EE+ FFD G+ LDVALR FL +F+LTG+TQERER++ HF++RY+ CN D +N EDACHTL CA+++LNT+LH Q+ +M+ +FI NL +LNDGENFP D L+ L+ +I+ P+ W LD+E +++D++ + +N N D P S + ++ GYV+RK EP G+KT GKRGWK+YY LRD+ +Y +KD
Sbjct: 476 YFQPTKNADYPSAYRLAKRLYDLEGFKKADVAKHLGKKNDFSQLVAEEYLKFFDFVGIPLDVALRQFLQQFSLTGETQERERVLAHFTRRYMECNPDSFNSEDACHTLTCAIMLLNTDLHGQNIGRRMTCGEFIDNLAELNDGENFPRDVLKTLYLSIKSRPLEWALDEEGEAT---SETDLLLEESRRVNLGHNPFLDVPDPSQATEYKRGYVMRKCCTEPDGKKTPLGKRGWKMYYATLRDMVLYFHKD 723 HSP 2 Score: 107.842 bits (268), Expect = 6.297e-20 Identity = 62/180 (34.44%), Postives = 105/180 (58.33%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDK-RNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNM-TNLRCMSGNDVPFFCQ-PYHSISGI 2578
+ IHH+ AT+AVDY KK++V R++T + YL Q ++ E++ WID IN+VAA LS P G+ + +K +P T + QL+ H+ V+EL++ + K PP K K R E++E ++ EL+R++TY+ LL+ ++A + ++L M+ ++ Q P HS+S +
Sbjct: 740 VRIHHSLATKAVDYTKKQHVLRLRTAEWAVYLLQSSDPTELQGWIDTINFVAASLSAPPLPGGVGSQKKFQRPLLPS-SYTRLNLTQQLQHHESKVVELQESLEEHKRYPPSKGAKERIIREYEEKEQYLHFELERFQTYAHLLKSKMASFPELESSLVDMAIGEMEEPTQSPSHSLSPL 918
BLAST of PH and SEC7 domain-containing protein vs. TrEMBL
Match: A0A0L8FH99 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22020622mg PE=4 SV=1) HSP 1 Score: 276.944 bits (707), Expect = 3.450e-74 Identity = 126/253 (49.80%), Postives = 181/253 (71.54%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVG--IVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
YHQP K++DR +A RLA+RLY+ DGF+ +DV++HL K+NDFS +V EE+ FFD +G LDVALR FL +F+L G+TQERER++ HFSKRY++ N D YN EDACHTL CA+++LNT+LH Q+ KM+ ++FI+NL +LNDG+NFP ++L +++ AI+ EPI W DD+L N + +S+ N + P + + ++ GYV+RK +P GR+T+FGKRGWK++Y LRD+ +YL+KD
Sbjct: 544 YHQPFKSVDRPSAARLAKRLYNLDGFRKSDVSRHLCKKNDFSNLVAEEYLQFFDFTGNTLDVALRTFLKQFSLIGETQERERVLAHFSKRYMTTNPDTYNSEDACHTLTCAIMLLNTDLHGQNVGRKMNCNEFIENLCELNDGDNFPKEDLRQIYAAIKMEPIEWAPDDDLQDNETTVTNDRRQVPLSETPSRLGHNPFLEIPDPNQTTEYKKGYVMRKCCLDPDGRRTSFGKRGWKMFYASLRDMILYLHKD 796 HSP 2 Score: 109.383 bits (272), Expect = 2.644e-20 Identity = 61/149 (40.94%), Postives = 90/149 (60.40%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDK-RNRMEFDESIRFREEELQRYKTYSQLLEFEIA 2491
I IHH+ ATRA DY KK++VFR+ T +EYLFQ ++ KE++ W++ INYVAA LS P GI + +K +P T + QL HQ+ V LEK + + PP+K K R ++ E +F E EL+R++TY LL+ +++
Sbjct: 813 IRIHHSIATRASDYTKKQHVFRLHTSDWAEYLFQTSDSKELQEWMETINYVAASLSAPPLPGGIGSKKKFQRPLMPS-SYTKKNLSEQLAHHQEKVTHLEKELHEHRLCPPEKGAKARIIHDYVEKEQFLESELKRFQTYKYLLQSKLS 960
BLAST of PH and SEC7 domain-containing protein vs. TrEMBL
Match: V4A281 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_209989 PE=4 SV=1) HSP 1 Score: 257.684 bits (657), Expect = 1.621e-71 Identity = 122/251 (48.61%), Postives = 169/251 (67.33%), Query Frame = 2
Query: 821 YHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
YHQP K++DR +A RLA+RLY DGF+ +DV++HL K+N+FS +V EE+ F+ +G LDV+LR FL +F LTG+TQERER++ HFS RY+ CN +N EDACHTL CA+++LNT+LH Q+ KM+ S+FI+NL DLNDGENFP D L+ +F +I+ E + W M+ + +Q I N + D P S + ++ GYV+RK + GR+T GKR WK++Y LRDL +YLYKD
Sbjct: 57 YHQPLKSVDRPSASRLAKRLYALDGFRKSDVSRHLFKKNEFSNLVAEEYLKNFEFTGDTLDVSLRKFLKQFCLTGETQERERVLAHFSHRYMECNPGTFNSEDACHTLTCAMMLLNTDLHGQTVGRKMTCSEFIENLADLNDGENFPKDILKTVFNSIKGEQLEWA---------------MVSVPQQFIGQNPFL--DVPDPSKTIEYKKGYVMRKCCMDADGRRTGLGKRSWKMFYAVLRDLILYLYKD 290 HSP 2 Score: 97.4413 bits (241), Expect = 3.877e-17 Identity = 54/162 (33.33%), Postives = 92/162 (56.79%), Query Frame = 2
Query: 2024 ILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDK-RNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNM 2506
++ A + I +HH T+A DY KK++VFR+++ +E+LFQ +N KE++ W+D +N+VAA S EP+ G + R + T +R Q ++H++ V LE+ + + P+K K R+ ++ + + EL+RYKTY LL+ +I L M
Sbjct: 299 LVEVASNAIRVHHCLVTKATDYTKKQHVFRLQSAEWAEFLFQTSNSKELQEWMDTLNFVAAAFS-AEPLPGALGSKTGFQRPLLPVSYTRKTLREQFKNHEEKVESLEQELHQHRAGAPEKGAKSRDIQDYLAKETYLDFELKRYKTYVLLLQSKITALPEM 459
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Cavefish
Match: psda (pleckstrin and Sec7 domain containing a [Source:ZFIN;Acc:ZDB-GENE-090313-44]) HSP 1 Score: 224.172 bits (570), Expect = 5.288e-63 Identity = 111/246 (45.12%), Postives = 167/246 (67.89%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELV--GIVNLNKSDMMDISKQM--INTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYK 1567
D +AAKRLA+RLY+ DGF+ +DVA+HLSK N+FS++V EE+ ++F+ SG+ +D ALR+FL F L G+TQERER++ HFS+RY+ CN + ED+ HTL CAL++LNT+LH + K MS + FI NL+ LNDG++FP D L+ L+ +I+ E ++W +D+E + L M S M I++ N + S+++ + +G++VRK +P G++T GKRGWK +Y L+ L +YL K
Sbjct: 27 DLQAAKRLAKRLYNLDGFRRSDVARHLSKNNEFSRMVAEEYLSYFNFSGLTVDQALRVFLREFALMGETQERERVLSHFSRRYMQCNPNAVPSEDSVHTLTCALMLLNTDLHGHNVGKRMSCTQFIGNLEGLNDGQDFPKDLLKALYNSIKNEKLQWTIDEEELRKSFSELVDGRMDSASHTMKRISSGGNPLVSLAQQSSAQVYKNGFLVRKVHADPDGKRTPRGKRGWKSFYAILKGLVLYLQK 272 HSP 2 Score: 78.9518 bits (193), Expect = 1.029e-14 Identity = 50/151 (33.11%), Postives = 77/151 (50.99%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREE----ELQRYKTYSQLLEFEI 2488
I IHH+ A RA DY K+ NVF ++T +LFQ N ++M++WI IN VAA+ S P I + ++ S +P T QL++H+ + + L+ P D+R + + + + REE E RY TY+ LL +I
Sbjct: 290 ISIHHSLAMRASDYSKRPNVFYLRTADWRVFLFQAPNAEQMQSWITRINTVAAMFSAPPFPAAIGSQKRFSRPLLPGSN-TKLSQEEQLQAHETRFRAMSAELQELRSVP---QDRRTKGKDQDEGKQREEFLDFEKTRYGTYAMLLRAKI 436
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Cavefish
Match: psda (pleckstrin and Sec7 domain containing a [Source:ZFIN;Acc:ZDB-GENE-090313-44]) HSP 1 Score: 228.024 bits (580), Expect = 1.560e-60 Identity = 111/246 (45.12%), Postives = 167/246 (67.89%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELV--GIVNLNKSDMMDISKQM--INTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYK 1567
D +AAKRLA+RLY+ DGF+ +DVA+HLSK N+FS++V EE+ ++F+ SG+ +D ALR+FL F L G+TQERER++ HFS+RY+ CN + ED+ HTL CAL++LNT+LH + K MS + FI NL+ LNDG++FP D L+ L+ +I+ E ++W +D+E + L M S M I++ N + S+++ + +G++VRK +P G++T GKRGWK +Y L+ L +YL K
Sbjct: 1163 DLQAAKRLAKRLYNLDGFRRSDVARHLSKNNEFSRMVAEEYLSYFNFSGLTVDQALRVFLREFALMGETQERERVLSHFSRRYMQCNPNAVPSEDSVHTLTCALMLLNTDLHGHNVGKRMSCTQFIGNLEGLNDGQDFPKDLLKALYNSIKNEKLQWTIDEEELRKSFSELVDGRMDSASHTMKRISSGGNPLVSLAQQSSAQVYKNGFLVRKVHADPDGKRTPRGKRGWKSFYAILKGLVLYLQK 1408 HSP 2 Score: 81.6481 bits (200), Expect = 4.053e-15 Identity = 50/151 (33.11%), Postives = 77/151 (50.99%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREE----ELQRYKTYSQLLEFEI 2488
I IHH+ A RA DY K+ NVF ++T +LFQ N ++M++WI IN VAA+ S P I + ++ S +P T QL++H+ + + L+ P D+R + + + + REE E RY TY+ LL +I
Sbjct: 1426 ISIHHSLAMRASDYSKRPNVFYLRTADWRVFLFQAPNAEQMQSWITRINTVAAMFSAPPFPAAIGSQKRFSRPLLPGSN-TKLSQEEQLQAHETRFRAMSAELQELRSVP---QDRRTKGKDQDEGKQREEFLDFEKTRYGTYAMLLRAKI 1572
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Cavefish
Match: psd3l (PH and SEC7 domain-containing protein 3 [Source:NCBI gene;Acc:103038592]) HSP 1 Score: 215.698 bits (548), Expect = 3.324e-60 Identity = 109/248 (43.95%), Postives = 158/248 (63.71%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLD-DELVG----IVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
D+EAA+RLARRLY +GF+ +DVAKHL K NDFS++V EE+ +FF+ +GM LD +LR FL F L G+TQERER++ H+S RY CN + +D H L CAL++LNT+LH Q+ KM+ +FI NL LN G++FP + L+ L+ +I+ E + W +D DEL + + K + S I++ N D D N+ + +G++ RK + G+KT GKRGWK +Y L+ + +YL KD
Sbjct: 41 DQEAAQRLARRLYHLEGFRRSDVAKHLGKNNDFSKMVAEEYLSFFEFTGMTLDQSLRSFLKAFALMGETQERERVLIHYSNRYYQCNPTIIASQDGVHCLTCALMLLNTDLHGQNIGKKMTCQEFINNLDGLNAGQDFPRELLKALYNSIKNEKLEWAIDGDELKKSLSELADNKKDNAHTKSISRISSGSNPFLDIAHDPNAAVYKTGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGMILYLQKD 288 HSP 2 Score: 81.6481 bits (200), Expect = 1.411e-15 Identity = 52/151 (34.44%), Postives = 79/151 (52.32%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRM-EFDESIRFREEELQRYKTYSQLLEFEIAKL 2497
I HHA A +AVDY KK NV ++KT +LFQ + +EM++WI IN VAA+ S P I + +K S +P T QL+SH+ + + ++ + PP K K + E+ + E E RY+TY +LL+ + +L
Sbjct: 305 ISTHHALAIQAVDYEKKPNVLKLKTADWRVFLFQAQSPEEMDSWIRIINSVAAMFSAPSFPAAIGSQKKFSRPLLP-ATTTRMSQEEQLKSHEAKLKHISTELAEHRSYPPDKKVKAKEVDEYRLKEHYLEFEENRYETYVKLLKEGVKEL 454
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000052239.1 (PH and SEC7 domain-containing protein 1 [Source:NCBI gene;Acc:103042928]) HSP 1 Score: 213.001 bits (541), Expect = 1.554e-58 Identity = 110/248 (44.35%), Postives = 158/248 (63.71%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELV--GIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDR 1579
D EAAKRLA+RL++ DGF+ DVA+HLSK NDFS++V EE+ +F+ +G LD ALR FL F L G+TQERER++ HFS+RY+ CN + ED+ HTL CAL++LNT+LH Q+ K MS + FI NL+ LN G +FP + L+ L+ +I+ E ++W +D+E + L + S+ M T I S + + +G++VRK + G++T GKRGWK +Y L+ L +YL K R
Sbjct: 98 DLEAAKRLAKRLFNLDGFRKCDVARHLSKNNDFSRMVAEEYLGYFNFTGQTLDQALRSFLLEFALMGETQERERVLAHFSRRYLQCNPMLLLSEDSVHTLTCALMLLNTDLHGQNIGKRMSCTQFIGNLEGLNSGHDFPRELLKALYNSIKNEKLQWTIDEEELRKSFSELGEQREESNSRGMKRTGSGI----VPASGALLYKTGFLVRKVHADCDGKRTPRGKRGWKTFYAVLKGLVLYLQKGEYR 341 HSP 2 Score: 75.8702 bits (185), Expect = 1.287e-13 Identity = 49/144 (34.03%), Postives = 74/144 (51.39%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPP-KKSDKRNRMEFDESIRFREEELQRYKTYSQLL 2476
+ IHH+ A RA DY K+ NVF ++T YLFQ N ++M++WI IN VAA+ S P I + +K S +P + Q+++H+ ++ L+ PP +K R E+ + E E RY+TYS LL
Sbjct: 355 VSIHHSLAIRATDYHKRPNVFYLRTADWRVYLFQAPNAEQMQSWITRINTVAAMFSAPPLPAAIGSQKKFSRPLLP-GSASKLSQEEQVQAHEARFHATSTELAELRSYPPDRKVKGRELEEYRLREEYLEFEKTRYETYSMLL 497
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Cavefish
Match: psd3l (PH and SEC7 domain-containing protein 3 [Source:NCBI gene;Acc:103038592]) HSP 1 Score: 219.55 bits (558), Expect = 5.739e-58 Identity = 107/248 (43.15%), Postives = 157/248 (63.31%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDE-----LVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
D+EAA+RLARRLY +GF+ +DVAKHL K NDFS++V EE+ +FF+ +GM LD +LR FL F L G+TQERER++ H+S RY CN + +D H L CAL++LNT+LH Q+ KM+ +FI NL LN G++FP + L+ L+ +I+ E + W +D + L + + K + S I++ N D D N+ + +G++ RK + G+KT GKRGWK +Y L+ + +YL KD
Sbjct: 946 DQEAAQRLARRLYHLEGFRRSDVAKHLGKNNDFSKMVAEEYLSFFEFTGMTLDQSLRSFLKAFALMGETQERERVLIHYSNRYYQCNPTIIASQDGVHCLTCALMLLNTDLHGQNIGKKMTCQEFINNLDGLNAGQDFPRELLKALYNSIKNEKLEWAIDGDELKKSLSELADNKKDNAHTKSISRISSGSNPFLDIAHDPNAAVYKTGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGMILYLQKD 1193 HSP 2 Score: 85.5001 bits (210), Expect = 2.518e-16 Identity = 55/154 (35.71%), Postives = 81/154 (52.60%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQ----RYKTYSQLLEFEIAKL 2497
I HHA A +AVDY KK NV ++KT +LFQ + +EM++WI IN VAA+ S P I + +K S +P T QL+SH+ + + ++ + PP K K E DE R +E L+ RY+TY +LL+ + +L
Sbjct: 1210 ISTHHALAIQAVDYEKKPNVLKLKTADWRVFLFQAQSPEEMDSWIRIINSVAAMFSAPSFPAAIGSQKKFSRPLLPA-TTTRMSQEEQLKSHEAKLKHISTELAEHRSYPPDK--KVKAKEVDE-YRLKEHYLEFEENRYETYVKLLKEGVKEL 1359
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Sea Lamprey
Match: si:dkey-283b15.4 (cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502]) HSP 1 Score: 97.4413 bits (241), Expect = 1.276e-21 Identity = 53/159 (33.33%), Postives = 88/159 (55.35%), Query Frame = 2
Query: 866 LARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYN-----GEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDD 1324
+A+ LY +G T + ++L +R+DF+ V F + + + L ALR FL F L G+ Q+ +R+M F+ RY CN ++ D C+ L A+I+LNT+LH+ + K ++ FI + +NDG + P + L L+ +I+ EP + P DD
Sbjct: 99 IAQFLYKGEGLNKTAIGEYLGERDDFNIQVLHAFVELHEFANLNLVQALRQFLWSFRLPGEAQKIDRMMEAFATRYCQCNAGVFQSTGGVATDTCYVLSFAIIMLNTSLHNPNVRDKPTTERFILMNRGINDGGDLPEELLRNLYDSIKNEPFKIPEDD 257
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001471.1 (pep scaffold:Pmarinus_7.0:GL477283:166775:173339:-1 gene:ENSPMAG00000001328.1 transcript:ENSPMAT00000001471.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 83.1889 bits (204), Expect = 1.769e-18 Identity = 47/122 (38.52%), Postives = 71/122 (58.20%), Query Frame = 2
Query: 953 VGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNG---EDACHTLVCALIILNTNLHSQSF---PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKE 1300
V F + D SG+ LD ALRLF L G+ Q+ ER++ FS+RY +CN + + ED L A+++LNT+++S S KM DFI+NL+ ++DGE+ P D L ++ I K+
Sbjct: 57 VSRCFVDEMDFSGLELDEALRLFQTHVRLQGEAQKVERLVEVFSRRYCACNPAVVSALCSEDTVFVLAFAIVLLNTDMYSPSVRHDRKMRLDDFIKNLRGVDDGEDIPRDFLVGIYERIRKQ 178
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Sea Lamprey
Match: psda (pleckstrin and Sec7 domain containing a [Source:ZFIN;Acc:ZDB-GENE-090313-44]) HSP 1 Score: 79.7221 bits (195), Expect = 2.321e-16 Identity = 52/156 (33.33%), Postives = 78/156 (50.00%), Query Frame = 2
Query: 2036 ADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKEN---PPKKSDKRNRMEFDESIR--FREEELQRYKTYSQLLEFEI 2488
A + +HHA ATRA DY K+ +V ++KT +L Q N +EME+WI IN VA L S P I + ++ S +P T QL SH+ +L+ + S+L ++ PP R + D ++ + E E RY TY LL ++
Sbjct: 64 AKQAVSVHHALATRATDYTKRPHVLKLKTADWRVFLLQAPNTQEMESWITRINLVATLFSAPPFPAAIGSQKRFSRPLLP-ASATKLPQEEQLRSHED---KLKGVTSDLDQHRSYPPDPRRVRAKEADDYRLKQHYLEFEKTRYGTYVTLLRAKM 215
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Sea Lamprey
Match: iqsec1b (IQ motif and Sec7 domain ArfGEF 1b [Source:ZFIN;Acc:ZDB-GENE-120813-1]) HSP 1 Score: 81.2629 bits (199), Expect = 8.949e-16 Identity = 51/171 (29.82%), Postives = 87/171 (50.88%), Query Frame = 2
Query: 911 VAKHLSKRNDFS-QIVGEEFANF---------------FDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDM---YNGEDACHTLVCALIILNTNLHSQSFP---KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKS 1357
VA L +R S Q++GE N D SGM LD ALR+F + G+ Q+ ER++ FS+RY CN + + D L A+++LNT+++S + KM DF++NL+ ++DG + P + L ++ I++ ++ DD + + N+ K+
Sbjct: 494 VAHFLLQRKGLSRQMIGEFLGNRQRAFNRDVLDCVVDEMDFSGMELDEALRMFQAHIRVQGEAQKVERLIEAFSQRYCMCNPGVVKNFQNPDTIFILAFAIVLLNTDMYSPNVKPERKMKLDDFVKNLRGVDDGADIPREILVGIYERIQRGELKTN-DDHVTQVANVEKT 663
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007609.1 (pep scaffold:Pmarinus_7.0:GL477333:80854:108205:-1 gene:ENSPMAG00000006851.1 transcript:ENSPMAT00000007609.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 75.8702 bits (185), Expect = 1.793e-14 Identity = 48/155 (30.97%), Postives = 81/155 (52.26%), Query Frame = 2
Query: 911 VAKHLSKRNDFS-QIVGEEFANF---------------FDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDM---YNGEDACHTLVCALIILNTNLHSQSFP---KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIR 1309
VA+ L +R S Q++G+ N D +GM +D ALR F G+ + G+ Q+ ER++ FS+RY CN + + D L A+I+LNT+ +S + KM DFI+NL+ ++DG++ P + L ++ I K+ ++
Sbjct: 71 VAQFLLQRKGLSRQMIGDFLGNRQKQFNRDVLDCVVEEMDFAGMDIDEALRKFQGQVRVQGEAQKVERMIEAFSQRYCVCNSVLLRQFRNPDTIFILAFAIILLNTDRYSPNVKAERKMKLEDFIKNLRGVDDGKDIPREMLLSIYDRISKKELK 225
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Yeast
Match: SEC7 (Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors; involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles [Source:SGD;Acc:S000002577]) HSP 1 Score: 92.0485 bits (227), Expect = 3.625e-19 Identity = 64/208 (30.77%), Postives = 105/208 (50.48%), Query Frame = 2
Query: 728 NSQSIDTDDENRLIDFS--------CIFINADDEFSGKRYHQPPKAIDREAAK-----RLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIR 1309
+SQ+ID DD + + CI I F+ K P I + K +A+ L + +G + V +L + +D + + F + FD +GM + ALR FL F L G+ Q+ +R M F++R+V N +++ D + L +LI+LNT+LHS KMS +F++N + +++G + P D LE LF I I+
Sbjct: 809 SSQNIDADDPTQFENLKLRKTALSECIAI-----FNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFVDEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPGVFSKADTAYVLSYSLIMLNTDLHSSQIKNKMSLQEFLENNEGIDNGRDLPRDFLEGLFNEIANNEIK 1011
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Yeast
Match: GEA2 (Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA2 has a paralog, GEA1, that arose from the whole genome duplication [Source:SGD;Acc:S000000748]) HSP 1 Score: 64.6994 bits (156), Expect = 6.518e-11 Identity = 46/136 (33.82%), Postives = 70/136 (51.47%), Query Frame = 2
Query: 962 EFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMY-------NGEDACHT----------LVCALIILNTNLHS-QSFPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWP 1315
E+ FD SG+R+D A+R+ L +F L G++Q+ ERI+ FS Y C Y N ED T L ++I+LNT+LH+ Q MS D+ NLK + ++FP L+ ++ +I + I P
Sbjct: 626 EYIRLFDFSGLRVDEAIRILLTKFRLPGESQQIERIIEAFSSAY--CENQDYDPSKISDNAEDDISTVQPDADSVFILSYSIIMLNTDLHNPQVKEHMSFEDYSGNLKGCCNHKDFPFWYLDRIYCSIRDKEIVMP 759
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Yeast
Match: GEA1 (Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA1 has a paralog, GEA2, that arose from the whole genome duplication [Source:SGD;Acc:S000003792]) HSP 1 Score: 61.2326 bits (147), Expect = 8.410e-10 Identity = 42/145 (28.97%), Postives = 72/145 (49.66%), Query Frame = 2
Query: 959 EEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRY---------------VSCNGDMYNGE----------DACHTLVCALIILNTNLHS-QSFPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWP 1315
+EF + FD G+R+D A+R+ L +F L G++Q+ ERI+ FS +Y NG E D+ L ++I+LNT+ H+ Q M+ D+ NL+ +G++FP L +++ +I+ + I P
Sbjct: 607 KEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMP 751
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Nematostella
Match: EDO34812 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN91]) HSP 1 Score: 152.91 bits (385), Expect = 1.101e-40 Identity = 84/245 (34.29%), Postives = 128/245 (52.24%), Query Frame = 2
Query: 836 KAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYK 1567
+ ++ E+ + LA RL+ DGF VA L K F + V E+ F+ SG+ + ALR+F F L G+TQERERI+ FS RY CN Y DA HTLVCA+++LNT+ H ++ KM+ S F++N+ L DG +FP D L+ ++ I P+ W + + + +F I DE + F G + RK E G+KT+ KR W ++ L+ + ++L+K
Sbjct: 2 RWVEHESPRTLAFRLFSLDGFTKDQVAPQLYKNTTFGKTVAVEYLKLFNFSGLSIVEALRVFTKAFLLIGETQERERILIPFSNRYYQCNTPDYGSADAVHTLVCAVLLLNTDHHGENIGKKMTLSQFLENMAGLCDGHDFPKDLLKSIYQEIRTNPLEWS---------GIETAWSPPVILHFCTLSFQIQVDE----KDKLFKEGLLYRKVTMESEGKKTSAWKRKWIPFHATLKGMVLFLHK 233 HSP 2 Score: 55.8398 bits (133), Expect = 4.508e-8 Identity = 28/65 (43.08%), Postives = 36/65 (55.38%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDP--EPIIG 2236
+ +HH+ A+RA DY K+ VF+ T E+LFQ +M WI IN VAA S P P IG
Sbjct: 250 LGVHHSLASRATDYKKRPFVFKFVTADWREFLFQARGRTDMSEWIAAINQVAATFSAPPLPPPIG 314
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Nematostella
Match: EDO34882 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN35]) HSP 1 Score: 105.531 bits (262), Expect = 1.501e-23 Identity = 57/143 (39.86%), Postives = 89/143 (62.24%), Query Frame = 2
Query: 932 RNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCN-GDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNK 1354
+NDF+ V + FA FD +GM +DVALR FL +F + G+ Q+ ER+M F+++Y+SCN D + +D L A+++LNT+LHS + K M+ DFI+NL+ N+G NFPS++L ++ + K+ P D + L K
Sbjct: 90 QNDFNMAVLKCFAESFDFTGMEIDVALRTFLAQFRIPGEAQKIERLMEVFAEQYISCNPTDDTSAQDKVLILAFAIVMLNTDLHSPNVKKRMTQEDFIRNLEGTNNGGNFPSESLAGIYRRVFKKEFT-PARDHVTMTAKLEK 231
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Nematostella
Match: EDO38004 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEA8]) HSP 1 Score: 82.8037 bits (203), Expect = 1.136e-16 Identity = 50/154 (32.47%), Postives = 82/154 (53.25%), Query Frame = 2
Query: 866 LARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDD 1324
LA L +G T + +L + +F+ V +F + M L ALR FL F L G+ Q+ +R+M F+++Y + N ++ D C+ L A+I+LNT+LH+ + K + FIQ + +N GE+ D L L+ +I+ E + P DD
Sbjct: 92 LADFLLKEEGLNKTQIGNYLGENKEFNLDVFAKFVDLHKFKDMILVQALRQFLWSFRLPGEAQKIDRMMEAFAQKYCADNPGLFTSTDTCYVLSFAIILLNTSLHNPNVKDKPTVEKFIQMNRGINCGEDLDRDFLVALYDSIKSEEFKIPEDD 245
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Nematostella
Match: EDO31538 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXN1]) HSP 1 Score: 84.7297 bits (208), Expect = 1.489e-16 Identity = 50/155 (32.26%), Postives = 87/155 (56.13%), Query Frame = 2
Query: 860 KRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK---MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWP 1315
+ +AR L + + +++ K+++ S+++ + F F+ +R+D LR FL F L G++ E IM FS+ + CN ++Y +DA TL A+I+LN + H+ + + M DF +NL+ +N G +FP+ LEE+F I+ E I P
Sbjct: 711 EEMARLLRENPRLDKKTIGEYIGKKDN-SKVL-DAFVRSFEFHDLRVDEGLRQFLESFRLPGESPVIEHIMEFFSEVFFECNPEVYANKDAVFTLAYAVIMLNVDQHNANIKQQKPMVLEDFKRNLRKINGGNDFPATMLEEIFTCIKNEEIVMP 863
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Nematostella
Match: EDO29369 (pep supercontig:ASM20922v1:NEMVEscaffold_1160:24851:31523:-1 gene:NEMVEDRAFT_v1g144802 transcript:EDO29369 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 67.0106 bits (162), Expect = 4.027e-12 Identity = 36/103 (34.95%), Postives = 60/103 (58.25%), Query Frame = 2
Query: 1019 FLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFP-KMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDD 1324
FL F L G+ Q+ +R+M F+++Y + N ++ D C+ L A+I+LNT+LH+ + K + FIQ + +N GE+ D L L+ +I+ E + P DD
Sbjct: 3 FLWSFRLPGEAQKIDRMMEAFAQKYCADNPGLFTSTDTCYVLSFAIILLNTSLHNPNVKDKPTVEKFIQMNRGINCGEDLDRDFLVALYDSIKSEEFKIPEDD 105
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000003646.2 (PH and SEC7 domain-containing protein 1 [Source:NCBI gene;Acc:101166656]) HSP 1 Score: 228.794 bits (582), Expect = 1.524e-64 Identity = 113/251 (45.02%), Postives = 168/251 (66.93%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELV--GIVNLNKSDMMDISKQM--INTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDRS 1582
D +AAKRLA+RLY+ DGF+ +DVA+HL K N+FSQ+V EE+ + F+ G+ +D ALRLFL F L G+TQERER++ HFS+RY CN + + ED+ HTL CA+++LNT+LH + K MS + FI NL+ LNDG++FP + L+ L+ +I+ E ++W +D+E + I L +S S M + + N + ++ +MSG++VRK +P G++TA GKRGWK +Y L+ L +YL KD R+
Sbjct: 38 DLQAAKRLAKRLYNLDGFRKSDVARHLGKNNEFSQLVAEEYLSCFNFKGLTIDQALRLFLSHFALMGETQERERVLAHFSRRYKHCNPESLSTEDSIHTLTCAIMLLNTDLHGNNVGKRMSCTQFISNLEGLNDGKDFPKELLKILYTSIKTEKLQWTIDEEELRKSISELAESRTDSASHTMKRLGSGGNPMVGVAQQADGELYMSGFLVRKVHADPDGKRTARGKRGWKSFYAMLKGLVLYLQKDEYRT 288 HSP 2 Score: 76.6406 bits (187), Expect = 5.953e-14 Identity = 48/152 (31.58%), Postives = 77/152 (50.66%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQ----RYKTYSQLLEFEIA 2491
+ +HH+ A RAVDY K+ NVF ++T +LFQ N ++M++WI IN VAA+ S P I + ++ S +P T Q + H+ + S L E P D++ + E + R+E L+ RY TY+ LL +++
Sbjct: 301 VSVHHSLAMRAVDYSKRPNVFYLRTADWRVFLFQAPNAEQMQSWITRINVVAAMFSAPPFPAAIGSQKRFSRPLLPGSG-TKLSQEEQAKFHEN---RFRAVSSELLELTPATPDRKAKGRELEEQKLRKEYLEFEKTRYGTYAMLLRAKLS 448
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000032974.1 (PH and SEC7 domain-containing protein 1 [Source:NCBI gene;Acc:101166656]) HSP 1 Score: 228.409 bits (581), Expect = 4.992e-64 Identity = 113/251 (45.02%), Postives = 168/251 (66.93%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELV--GIVNLNKSDMMDISKQM--INTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDRS 1582
D +AAKRLA+RLY+ DGF+ +DVA+HL K N+FSQ+V EE+ + F+ G+ +D ALRLFL F L G+TQERER++ HFS+RY CN + + ED+ HTL CA+++LNT+LH + K MS + FI NL+ LNDG++FP + L+ L+ +I+ E ++W +D+E + I L +S S M + + N + ++ +MSG++VRK +P G++TA GKRGWK +Y L+ L +YL KD R+
Sbjct: 65 DLQAAKRLAKRLYNLDGFRKSDVARHLGKNNEFSQLVAEEYLSCFNFKGLTIDQALRLFLSHFALMGETQERERVLAHFSRRYKHCNPESLSTEDSIHTLTCAIMLLNTDLHGNNVGKRMSCTQFISNLEGLNDGKDFPKELLKILYTSIKTEKLQWTIDEEELRKSISELAESRTDSASHTMKRLGSGGNPMVGVAQQADGELYMSGFLVRKVHADPDGKRTARGKRGWKSFYAMLKGLVLYLQKDEYRT 315 HSP 2 Score: 77.411 bits (189), Expect = 4.248e-14 Identity = 48/152 (31.58%), Postives = 77/152 (50.66%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQ----RYKTYSQLLEFEIA 2491
+ +HH+ A RAVDY K+ NVF ++T +LFQ N ++M++WI IN VAA+ S P I + ++ S +P T Q + H+ + S L E P D++ + E + R+E L+ RY TY+ LL +++
Sbjct: 328 VSVHHSLAMRAVDYSKRPNVFYLRTADWRVFLFQAPNAEQMQSWITRINVVAAMFSAPPFPAAIGSQKRFSRPLLPGSG-TKLSQEEQAKFHEN---RFRAVSSELLELTPATPDRKAKGRELEEQKLRKEYLEFEKTRYGTYAMLLRAKLS 475
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000045701.1 (PH and SEC7 domain-containing protein 1 [Source:NCBI gene;Acc:101166656]) HSP 1 Score: 231.106 bits (588), Expect = 1.452e-61 Identity = 113/251 (45.02%), Postives = 168/251 (66.93%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELV--GIVNLNKSDMMDISKQM--INTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDRS 1582
D +AAKRLA+RLY+ DGF+ +DVA+HL K N+FSQ+V EE+ + F+ G+ +D ALRLFL F L G+TQERER++ HFS+RY CN + + ED+ HTL CA+++LNT+LH + K MS + FI NL+ LNDG++FP + L+ L+ +I+ E ++W +D+E + I L +S S M + + N + ++ +MSG++VRK +P G++TA GKRGWK +Y L+ L +YL KD R+
Sbjct: 1164 DLQAAKRLAKRLYNLDGFRKSDVARHLGKNNEFSQLVAEEYLSCFNFKGLTIDQALRLFLSHFALMGETQERERVLAHFSRRYKHCNPESLSTEDSIHTLTCAIMLLNTDLHGNNVGKRMSCTQFISNLEGLNDGKDFPKELLKILYTSIKTEKLQWTIDEEELRKSISELAESRTDSASHTMKRLGSGGNPMVGVAQQADGELYMSGFLVRKVHADPDGKRTARGKRGWKSFYAMLKGLVLYLQKDEYRT 1414 HSP 2 Score: 79.7221 bits (195), Expect = 1.423e-14 Identity = 49/153 (32.03%), Postives = 77/153 (50.33%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVL-ELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQ----RYKTYSQLLEFEIA 2491
+ +HH+ A RAVDY K+ NVF ++T +LFQ N ++M++WI IN VAA+ S P I + ++ S RP + G + E K + S L E P D++ + E + R+E L+ RY TY+ LL +++
Sbjct: 1427 VSVHHSLAMRAVDYSKRPNVFYLRTADWRVFLFQAPNAEQMQSWITRINVVAAMFSAPPFPAAIGSQKRFS-----RPLLPGSGTKLSQEEQAKFHENRFRAVSSELLELTPATPDRKAKGRELEEQKLRKEYLEFEKTRYGTYAMLLRAKLS 1574
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000034031.1 (PH and SEC7 domain-containing protein 1 [Source:NCBI gene;Acc:101166258]) HSP 1 Score: 220.32 bits (560), Expect = 4.048e-61 Identity = 112/251 (44.62%), Postives = 165/251 (65.74%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMM---DISKQM--INTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDR 1579
D AAKRLA+RLY+ +GF+ DV++HLSK NDFSQ + EE+ +FF+ +G+ LD ALR FL +F L G+TQERER++ HFS+RY+ CN + EDA HTL CAL++LNT+LH Q+ K MSSS FI NL+ LN+G++FP D L+ L+ +I+ + ++W LD+E + D + D SK M ++++ D + + + +G++VRK + G++ GKRGWK +Y L+ L +YL K R
Sbjct: 93 DVAAAKRLAKRLYNLEGFRKADVSRHLSKNNDFSQTIAEEYLSFFNFAGLNLDQALRTFLRQFALMGETQERERVLSHFSRRYMVCNPGVMPSEDAVHTLTCALMLLNTDLHGQNVGKRMSSSQFIANLEGLNNGQDFPKDLLKALYNSIKNQKLQWTLDEEELRKSFSELGDSLCEADTSKSMKRVSSSGKSLSDGMHSTGTLLYKNGFLVRKVHADSDGKRRPRGKRGWKTFYAILKGLILYLQKGEYR 343 HSP 2 Score: 83.1889 bits (204), Expect = 7.361e-16 Identity = 49/148 (33.11%), Postives = 76/148 (51.35%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRM-EFDESIRFREEELQRYKTYSQLLEFEI 2488
+ IHH+ A +A DY K+ NVF ++T YLFQ N ++M++WI IN VAAL S P I + +K S +P ++ Q+ SH+ + + +L+ PP + K M E+ + + + E RY TY LL +I
Sbjct: 357 VSIHHSLAMKASDYSKRPNVFYLRTADWRVYLFQAPNAEQMQSWITRINTVAALFSAPPFPAAIGSQKKFSRPLLP-GTMSKLSEEEQMRSHEARFRAISNDLGDLRSYPPDRKVKGREMEEYRQRDEYLDFEKTRYGTYIMLLRAKI 503
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000016044.2 (PH and SEC7 domain-containing protein 1 [Source:NCBI gene;Acc:101166258]) HSP 1 Score: 223.016 bits (567), Expect = 6.180e-59 Identity = 112/251 (44.62%), Postives = 165/251 (65.74%), Query Frame = 2
Query: 845 DREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPK-MSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMM---DISKQM--INTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDR 1579
D AAKRLA+RLY+ +GF+ DV++HLSK NDFSQ + EE+ +FF+ +G+ LD ALR FL +F L G+TQERER++ HFS+RY+ CN + EDA HTL CAL++LNT+LH Q+ K MSSS FI NL+ LN+G++FP D L+ L+ +I+ + ++W LD+E + D + D SK M ++++ D + + + +G++VRK + G++ GKRGWK +Y L+ L +YL K R
Sbjct: 1096 DVAAAKRLAKRLYNLEGFRKADVSRHLSKNNDFSQTIAEEYLSFFNFAGLNLDQALRTFLRQFALMGETQERERVLSHFSRRYMVCNPGVMPSEDAVHTLTCALMLLNTDLHGQNVGKRMSSSQFIANLEGLNNGQDFPKDLLKALYNSIKNQKLQWTLDEEELRKSFSELGDSLCEADTSKSMKRVSSSGKSLSDGMHSTGTLLYKNGFLVRKVHADSDGKRRPRGKRGWKTFYAILKGLILYLQKGEYR 1346 HSP 2 Score: 84.3445 bits (207), Expect = 6.116e-16 Identity = 49/148 (33.11%), Postives = 76/148 (51.35%), Query Frame = 2
Query: 2048 IHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRM-EFDESIRFREEELQRYKTYSQLLEFEI 2488
+ IHH+ A +A DY K+ NVF ++T YLFQ N ++M++WI IN VAAL S P I + +K S +P ++ Q+ SH+ + + +L+ PP + K M E+ + + + E RY TY LL +I
Sbjct: 1360 VSIHHSLAMKASDYSKRPNVFYLRTADWRVYLFQAPNAEQMQSWITRINTVAALFSAPPFPAAIGSQKKFSRPLLPG-TMSKLSEEEQMRSHEARFRAISNDLGDLRSYPPDRKVKGREMEEYRQRDEYLDFEKTRYGTYIMLLRAKI 1506
BLAST of PH and SEC7 domain-containing protein vs. Planmine SMEST
Match: SMESG000065299.1 (SMESG000065299.1) HSP 1 Score: 1613.2 bits (4176), Expect = 0.000e+0 Identity = 919/943 (97.45%), Postives = 920/943 (97.56%), Query Frame = 2
Query: 107 MDILKNDIXXXXXXXXXXXXXXXXVETLIYMESSEENRIDKNLIENEVAKNILAIHTPSPMVARSCFADSNCDSWKNVSIFSYSRSTANGELDNSNAFNHTNKYNVYNVIGDNKSPLTHNWISCQQVQNCSPELMRRNDIIFEENTQIDNNGDLDNSDYSDRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQDQQEISLVSDDKYNSQSIDTDDENRLIDFSCIFINADDEFSGKRYHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDRSCSQPKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPVDNENQSSAPDSADIPGVESCRPDGVNGDKDTXXXXXXXXXXXXXXXXXXXXXXXXXXKTKDLSPSSAETNSSTPLPTVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNMTNLRCMSGNDVPFFCQPYHSISGINQSLLIPNQGIILNQQLLNGISSSEGYMTNPILFNQPAALRFRPPALNNYVAISNNRRLRYRAPQSLTQSNIVPSVLSNXXXXXXXXXXXXXXXXXXXXXXXHETVFSPTSTNTFYEIV 2935
MDILKNDILDNSLMNNENSNNLSNVETLIYMESSEENRIDKNLIENEVAKNILAIHTPSPMVARSCFADSNCDSWKNVSIFSYSRSTANGELDNSNAFNHTNKYNVYNVIGDNKSPLTHNWISCQQVQNCSPELMRRNDIIFEENTQIDNNGDLDNSDYSDRSQSPINSVSSDDSSGTNSNSSANNSPDDAHSQDQQEISLVSDDKYNSQSIDTDDENRLIDFSCIFINADDEFSGKRYHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDRSCSQPKP + KVK N NNNNNNNNSSSNGNNPVDNENQ SAPDSADIPGVESCRPDGVNGDKDTSSNDQISNNSSSSSNNNNNSNQSNNDKTKDLSPSSAETNSSTPLPTVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNMTNLRCMSGNDVPFFCQPYHSISGINQSLLIPNQGIILNQQLLNGISSSEGYMTNPILFNQPAALRFRPPALNNYVAISNNRRLRYRAPQSLTQSNIVPSVLSNSGSVEPPVTPVTTTSISDSSPSPHETVFSPTSTNTFYEIV
Sbjct: 1 MDILKNDILDNSLMNNENSNNLSNVETLIYMESSEENRIDKNLIENEVAKNILAIHTPSPMVARSCFADSNCDSWKNVSIFSYSRSTANGELDNSNAFNHTNKYNVYNVIGDNKSPLTHNWISCQQVQNCSPELMRRNDIIFEENTQIDNNGDLDNSDYSDRSQSPINSVSSDDSSGTNSNSSANNSPDDAHSQDQQEISLVSDDKYNSQSIDTDDENRLIDFSCIFINADDEFSGKRYHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDRSCSQPKP--VSKRQNSVKKVKVKSFKHAKKPSNLNNNNNNNNSSSNGNNPVDNENQFSAPDSADIPGVESCRPDGVNGDKDTSSNDQISNNSSSSSNNNNNSNQSNNDKTKDLSPSSAETNSSTPLPTVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNMTNLRCMSGNDVPFFCQPYHSISGINQSLLIPNQGIILNQQLLNGISSSEGYMTNPILFNQPAALRFRPPALNNYVAISNNRRLRYRAPQSLTQSNIVPSVLSNSGSVEPPVTPVTTTSISDSSPSPHETVFSPTSTNTFYEIV 941
BLAST of PH and SEC7 domain-containing protein vs. Planmine SMEST
Match: SMESG000065299.1 (SMESG000065299.1) HSP 1 Score: 1599.33 bits (4140), Expect = 0.000e+0 Identity = 916/943 (97.14%), Postives = 917/943 (97.24%), Query Frame = 2
Query: 107 MDILKNDIXXXXXXXXXXXXXXXXVETLIYMESSEENRIDKNLIENEVAKNILAIHTPSPMVARSCFADSNCDSWKNVSIFSYSRSTANGELDNSNAFNHTNKYNVYNVIGDNKSPLTHNWISCQQVQNCSPELMRRNDIIFEENTQIDNNGDLDNSDYSDRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQDQQEISLVSDDKYNSQSIDTDDENRLIDFSCIFINADDEFSGKRYHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDRSCSQPKPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPVDNENQSSAPDSADIPGVESCRPDGVNGDKDTXXXXXXXXXXXXXXXXXXXXXXXXXXKTKDLSPSSAETNSSTPLPTVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNMTNLRCMSGNDVPFFCQPYHSISGINQSLLIPNQGIILNQQLLNGISSSEGYMTNPILFNQPAALRFRPPALNNYVAISNNRRLRYRAPQSLTQSNIVPSVLSNXXXXXXXXXXXXXXXXXXXXXXXHETVFSPTSTNTFYEIV 2935
MDILKNDILDNSLMNNENSNNLSNVETLIYMESSEENRIDKNLIENEVAKNILAIHTPSPMVARSCFADSNCDSWKNVSIFSYSRSTANGELDNSNAFNHTNKYNVYNVIGDNKSPLTHNWISCQQVQNCSPELMRRNDIIFEENTQIDNNGDLDNSDYSDRSQSPINSVSSDDSSGTNSNSSANNSPDDAHSQDQQEISLVSDDKYNSQSIDTDDENRLIDFSCIFINADDEFSGKRYHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIR DDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDRSCSQPKP + KVK N NNNNNNNNSSSNGNNPVDNENQ SAPDSADIPGVESCRPDGVNGDKDTSSNDQISNNSSSSSNNNNNSNQSNNDKTKDLSPSSAETNSSTPLPTVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNMTNLRCMSGNDVPFFCQPYHSISGINQSLLIPNQGIILNQQLLNGISSSEGYMTNPILFNQPAALRFRPPALNNYVAISNNRRLRYRAPQSLTQSNIVPSVLSNSGSVEPPVTPVTTTSISDSSPSPHETVFSPTSTNTFYEIV
Sbjct: 1 MDILKNDILDNSLMNNENSNNLSNVETLIYMESSEENRIDKNLIENEVAKNILAIHTPSPMVARSCFADSNCDSWKNVSIFSYSRSTANGELDNSNAFNHTNKYNVYNVIGDNKSPLTHNWISCQQVQNCSPELMRRNDIIFEENTQIDNNGDLDNSDYSDRSQSPINSVSSDDSSGTNSNSSANNSPDDAHSQDQQEISLVSDDKYNSQSIDTDDENRLIDFSCIFINADDEFSGKRYHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSFPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIR---DDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKDHDRSCSQPKP--VSKRQNSVKKVKVKSFKHAKKPSNLNNNNNNNNSSSNGNNPVDNENQFSAPDSADIPGVESCRPDGVNGDKDTSSNDQISNNSSSSSNNNNNSNQSNNDKTKDLSPSSAETNSSTPLPTVIKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNMTNLRCMSGNDVPFFCQPYHSISGINQSLLIPNQGIILNQQLLNGISSSEGYMTNPILFNQPAALRFRPPALNNYVAISNNRRLRYRAPQSLTQSNIVPSVLSNSGSVEPPVTPVTTTSISDSSPSPHETVFSPTSTNTFYEIV 938
BLAST of PH and SEC7 domain-containing protein vs. Planmine SMEST
Match: SMESG000041617.1 (SMESG000041617.1) HSP 1 Score: 323.168 bits (827), Expect = 8.501e-94 Identity = 151/265 (56.98%), Postives = 204/265 (76.98%), Query Frame = 2
Query: 782 IFINA-DDEFSGKRYHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
I INA D F YHQPPKA D+ AAKRLA+RLY DGFK++DV+KHLSKRNDFSQ+VGEEFANFFD + LD ALR FL +F L GDTQERER++HHFS+RYV CN ++YN E+ACHTLVCAL++LNT+LH + KMS DF+ ++ +LN+G++F ++L LF +I ++PIRW +D+EL+G+ K D DI+KQ+ + N+ + P ++ S+++MSGY++RK +KE R+T+ GKRGWKLY+GRL+DLT++LYKD
Sbjct: 323 IEINAPSDVFQEAIYHQPPKAADKSAAKRLAKRLYHLDGFKMSDVSKHLSKRNDFSQLVGEEFANFFDFTANTLDTALRKFLAKFILCGDTQERERVIHHFSRRYVQCNPNVYNCEEACHTLVCALMLLNTDLHGNNINRKMSCEDFVVSMAELNNGDHFDREDLIMLFNSILEKPIRWNIDNELIGLFQ-PKLDYNDINKQIHTNHLNLFLEVPSEATSKEYMSGYLLRKCIKESHYRRTSIGKRGWKLYFGRLQDLTLHLYKD 586 HSP 2 Score: 162.54 bits (410), Expect = 2.208e-40 Identity = 94/233 (40.34%), Postives = 140/233 (60.09%), Query Frame = 2
Query: 2036 ADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDK-RNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNMTNLRCMSGNDVPFFCQPYHSISGINQSLLIPNQGIILNQQLLNGISSSEGYMTNPILFNQPAALRFRPPALNNYV 2731
D+ I+++HAFA++A DY KK+NVFR++ GSEYLFQVN +E++ W+D +N+VAALLS P I S SSRS P +T+ I+ QLE+HQ+CVL LE+ +++L PP KSDK + + +++ +F E+EL RYKTYS+LLEFE+ LHNMT R + F PY + + S + + + N Q + + TN +F + P ++NN +
Sbjct: 694 GDTHIYLNHAFASKATDYSKKRNVFRLQVSNGSEYLFQVNEPREVDLWVDCLNFVAALLSPPVFNINSSKDSLDSSRSKINPALTSLNIKEQLENHQRCVLNLEQDLNHLSSKPPCKSDKTKLKWQYNRQRKFIEKELLRYKTYSRLLEFEMIHLHNMTIARL----NQQAFMDPY--LVPVQYSQIPGSSPLFYNHQTNQFVPAVNCVQTNIPVFQYHPSYSVPPGSINNSI 920
BLAST of PH and SEC7 domain-containing protein vs. Planmine SMEST
Match: SMESG000041617.1 (SMESG000041617.1) HSP 1 Score: 322.783 bits (826), Expect = 9.126e-94 Identity = 156/283 (55.12%), Postives = 211/283 (74.56%), Query Frame = 2
Query: 743 DTDDENRLI-----DFSCIFINA-DDEFSGKRYHQPPKAIDREAAKRLARRLYDCDGFKITDVAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQSF-PKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVNLNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYKD 1570
D DD++ L D I INA D F YHQPPKA D+ AAKRLA+RLY DGFK++DV+KHLSKRNDFSQ+VGEEFANFFD + LD ALR FL +F L GDTQERER++HHFS+RYV CN ++YN E+ACHTLVCAL++LNT+LH + KMS DF+ ++ +LN+G++F ++L LF +I ++PIRW +D+EL+G+ K D DI+KQ+ + N+ + P ++ S+++MSGY++RK +KE R+T+ GKRGWKLY+GRL+DLT++LYKD
Sbjct: 288 DDDDKSTLCGSDHGDKDEIEINAPSDVFQEAIYHQPPKAADKSAAKRLAKRLYHLDGFKMSDVSKHLSKRNDFSQLVGEEFANFFDFTANTLDTALRKFLAKFILCGDTQERERVIHHFSRRYVQCNPNVYNCEEACHTLVCALMLLNTDLHGNNINRKMSCEDFVVSMAELNNGDHFDREDLIMLFNSILEKPIRWNIDNELIGLFQ-PKLDYNDINKQIHTNHLNLFLEVPSEATSKEYMSGYLLRKCIKESHYRRTSIGKRGWKLYFGRLQDLTLHLYKD 569 HSP 2 Score: 162.54 bits (410), Expect = 2.177e-40 Identity = 94/233 (40.34%), Postives = 140/233 (60.09%), Query Frame = 2
Query: 2036 ADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDK-RNRMEFDESIRFREEELQRYKTYSQLLEFEIAKLHNMTNLRCMSGNDVPFFCQPYHSISGINQSLLIPNQGIILNQQLLNGISSSEGYMTNPILFNQPAALRFRPPALNNYV 2731
D+ I+++HAFA++A DY KK+NVFR++ GSEYLFQVN +E++ W+D +N+VAALLS P I S SSRS P +T+ I+ QLE+HQ+CVL LE+ +++L PP KSDK + + +++ +F E+EL RYKTYS+LLEFE+ LHNMT R + F PY + + S + + + N Q + + TN +F + P ++NN +
Sbjct: 677 GDTHIYLNHAFASKATDYSKKRNVFRLQVSNGSEYLFQVNEPREVDLWVDCLNFVAALLSPPVFNINSSKDSLDSSRSKINPALTSLNIKEQLENHQRCVLNLEQDLNHLSSKPPCKSDKTKLKWQYNRQRKFIEKELLRYKTYSRLLEFEMIHLHNMTIARL----NQQAFMDPY--LVPVQYSQIPGSSPLFYNHQTNQFVPAVNCVQTNIPVFQYHPSYSVPPGSINNSI 903
BLAST of PH and SEC7 domain-containing protein vs. Planmine SMEST
Match: SMESG000026134.1 (SMESG000026134.1) HSP 1 Score: 125.176 bits (313), Expect = 7.278e-29 Identity = 72/226 (31.86%), Postives = 123/226 (54.42%), Query Frame = 2
Query: 911 VAKHLSKRNDFSQIVGEEFANFFDLSGMRLDVALRLFLGRFTLTGDTQERERIMHHFSKRYVSCNGDMYNGEDACHTLVCALIILNTNLHSQ-SFPKMSSSDFIQNLKDLNDGENFPSDNLEELFGAIEKEPIRWPLDDELVGIVN------LNKSDMMDISKQMINTNFNIGYDEPRDSNSRDFMSGYVVRKWLKEPGGRKTAFGKRGWKLYYGRLRDLTIYLYK 1567
+A +LS + S+ V E D + ++L AL++F + ++TG++QER+RI+ HF+ R++ CN Y +DACHT+VCA+++LNT+LH Q S KM+ +FI NL + +L ++ I+K ++ D+ + + K + MIN + N+ N + F+SG ++RK +K+ G++ G RGWKL + L L + L+K
Sbjct: 197 IASYLSNCDPNSKSVALEIMKQIDFTNIQLVEALQIFNKKVSVTGESQERDRILTHFTSRFLECNPSSYKDKDACHTIVCAIMLLNTDLHGQVSKRKMTCKEFIDNLLTNYPDNQYKESDLISIYNYIKKNELKNNNSDDGNNTIRRKFTNFIIKPPKTNQESPMINMDSNLL-------NLQQFISGNIMRKCIKKSFGKRPGIGHRGWKLQFASLIGLQMLLFK 415 HSP 2 Score: 78.5666 bits (192), Expect = 1.637e-14 Identity = 60/206 (29.13%), Postives = 108/206 (52.43%), Query Frame = 2
Query: 1967 IKSTTDSVEVNASNTQPSLILPPADSEIHIHHAFATRAVDYVKKKNVFRIKTKYGSEYLFQVNNEKEMENWIDNINYVAALLSDPEPIIGISTMEKLSSRSIPRPKITTFGIRNQLESHQKCVLELEKIISNLKENPPKKSDKRNRMEFDESIRFREEELQRYKTYSQLLEFE-IAKLHNMTNLRCMSGNDVPFFCQPYHSISGIN 2581
+KS + + + S S+ + DS I IHH+FA+ V+ +K KN+F +K +EY F+V ++ ++ +W+++INY AALLS P PI+G + + +T Q++ H+ + E + L + + +N+ DE+I+F + E+ R++TY LL+ + + LHN N + V +P H++S N
Sbjct: 461 VKSISSKLPSSCSRENLSVSVEDVDSCIKIHHSFAS-VVEKLKHKNIFSLKLADQAEYFFKVKSD-QLNSWVNSINYAAALLSAP-PIVGAGQCGFY--KPLMPGYLTDLDKNAQIKIHETQLKSYEDSLKKL-----QLASIKNKAAQDENIKFCQFEISRFETYINLLKSKSLQDLHNNQNAKYRDIESVISNIEPSHNLSASN 656 The following BLAST results are available for this feature:
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of PH and SEC7 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30006490 ID=SMED30006490|Name=PH and SEC7 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3213bpback to top protein sequence of SMED30006490-orf-1 >SMED30006490-orf-1 ID=SMED30006490-orf-1|Name=SMED30006490-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=944bp MDILKNDILDNSLMNNENSNNLSNVETLIYMESSEENRIDKNLIENEVAKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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