TTF-type domain-containing protein

Overview
NameTTF-type domain-containing protein
Smed IDSMED30006431
Length (bp)3813
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TTF-type domain-containing protein (SMED30006431) t-SNE clustered cells

Violin plots show distribution of expression levels for TTF-type domain-containing protein (SMED30006431) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TTF-type domain-containing protein (SMED30006431) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TTF-type domain-containing protein (SMED30006431) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30006431

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30006431h1SMcG0011292 Contig6955uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30006431h1SMcG0011292 Contig6955newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
X1 cellSMED30006431h1SMcG0011292 SmedASXL_010281SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30006431h1SMcG0011292 SmedASXL_010281SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
whole organismSMED30006431h1SMcG0011292 sd1smed_ncbi_20240424PMID:24523458
Lin et al., 2014
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM1 (zinc finger MYM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:26253])

HSP 1 Score: 88.5817 bits (218), Expect = 6.226e-17
Identity = 71/276 (25.72%), Postives = 137/276 (49.64%), Query Frame = 2
Query:  221 GSNEWKIIGVILSSHERNTFHLDNFQAWKE---LDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL 1036
            G++ WK        HE++  HL + + W+E    D ++S + +   I+ + I+  ++Y + I+E ++     L  Q L  RG ++ + + N GNF + +E  A         L  + +Q  +  Y    IQ+ ++ I+   +   I++ +  +  +SII D T + +  E ++I +R+     P  S     A++I+E FLGFV  EE TG  +  T+   L+Q+ + ++ + GQ Y++ +N+K K   +  +  K +P +L+      F  LS +
Sbjct:  499 GTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQFCDGAVSDDLS---IHSKQIEGNKKYLKLIIENIL----FLGKQCLPLRGNDQSVSSVNKGNFLELLEMRAKDKGEETFRL--MNSQ--VDFYNSTQIQSDIIEIIKTEMLQDIVNEINDSSAFSIICDETINSAMKEQLSICVRY-----PQKS---SKAILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSII 755          
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM1 (zinc finger MYM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:26253])

HSP 1 Score: 88.5817 bits (218), Expect = 6.226e-17
Identity = 71/276 (25.72%), Postives = 137/276 (49.64%), Query Frame = 2
Query:  221 GSNEWKIIGVILSSHERNTFHLDNFQAWKE---LDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL 1036
            G++ WK        HE++  HL + + W+E    D ++S + +   I+ + I+  ++Y + I+E ++     L  Q L  RG ++ + + N GNF + +E  A         L  + +Q  +  Y    IQ+ ++ I+   +   I++ +  +  +SII D T + +  E ++I +R+     P  S     A++I+E FLGFV  EE TG  +  T+   L+Q+ + ++ + GQ Y++ +N+K K   +  +  K +P +L+      F  LS +
Sbjct:  499 GTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQFCDGAVSDDLS---IHSKQIEGNKKYLKLIIENIL----FLGKQCLPLRGNDQSVSSVNKGNFLELLEMRAKDKGEETFRL--MNSQ--VDFYNSTQIQSDIIEIIKTEMLQDIVNEINDSSAFSIICDETINSAMKEQLSICVRY-----PQKS---SKAILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSII 755          
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM1 (zinc finger MYM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:26253])

HSP 1 Score: 88.5817 bits (218), Expect = 6.226e-17
Identity = 71/276 (25.72%), Postives = 137/276 (49.64%), Query Frame = 2
Query:  221 GSNEWKIIGVILSSHERNTFHLDNFQAWKE---LDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL 1036
            G++ WK        HE++  HL + + W+E    D ++S + +   I+ + I+  ++Y + I+E ++     L  Q L  RG ++ + + N GNF + +E  A         L  + +Q  +  Y    IQ+ ++ I+   +   I++ +  +  +SII D T + +  E ++I +R+     P  S     A++I+E FLGFV  EE TG  +  T+   L+Q+ + ++ + GQ Y++ +N+K K   +  +  K +P +L+      F  LS +
Sbjct:  499 GTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQFCDGAVSDDLS---IHSKQIEGNKKYLKLIIENIL----FLGKQCLPLRGNDQSVSSVNKGNFLELLEMRAKDKGEETFRL--MNSQ--VDFYNSTQIQSDIIEIIKTEMLQDIVNEINDSSAFSIICDETINSAMKEQLSICVRY-----PQKS---SKAILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSII 755          
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM1 (zinc finger MYM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:26253])

HSP 1 Score: 88.5817 bits (218), Expect = 6.226e-17
Identity = 71/276 (25.72%), Postives = 137/276 (49.64%), Query Frame = 2
Query:  221 GSNEWKIIGVILSSHERNTFHLDNFQAWKE---LDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL 1036
            G++ WK        HE++  HL + + W+E    D ++S + +   I+ + I+  ++Y + I+E ++     L  Q L  RG ++ + + N GNF + +E  A         L  + +Q  +  Y    IQ+ ++ I+   +   I++ +  +  +SII D T + +  E ++I +R+     P  S     A++I+E FLGFV  EE TG  +  T+   L+Q+ + ++ + GQ Y++ +N+K K   +  +  K +P +L+      F  LS +
Sbjct:  499 GTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQFCDGAVSDDLS---IHSKQIEGNKKYLKLIIENIL----FLGKQCLPLRGNDQSVSSVNKGNFLELLEMRAKDKGEETFRL--MNSQ--VDFYNSTQIQSDIIEIIKTEMLQDIVNEINDSSAFSIICDETINSAMKEQLSICVRY-----PQKS---SKAILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSII 755          
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM5 (zinc finger MYM-type containing 5 [Source:HGNC Symbol;Acc:HGNC:13029])

HSP 1 Score: 53.9138 bits (128), Expect = 6.770e-12
Identity = 22/37 (59.46%), Postives = 28/37 (75.68%), Query Frame = 1
Query:   58 RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            R+FS  +Y R L NGE+  RSWL+YST KD+VFC +C
Sbjct:  557 RKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYC 593          

HSP 2 Score: 38.5058 bits (88), Expect = 6.770e-12
Identity = 18/57 (31.58%), Postives = 31/57 (54.39%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTID 346
            CKLF +  + +  + G  +W+ +  ILS HE +  H++N   + +L   + K K ID
Sbjct:  593 CKLFGEGKNQLKNENGCKDWQHLSHILSKHEESEMHVNNSVKYSKLKSDLKKNKAID 649          
BLAST of TTF-type domain-containing protein vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 65.4698 bits (158), Expect = 1.215e-10
Identity = 29/66 (43.94%), Postives = 45/66 (68.18%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 3693
            +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  333 DGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 398          
BLAST of TTF-type domain-containing protein vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 65.4698 bits (158), Expect = 1.222e-10
Identity = 29/66 (43.94%), Postives = 45/66 (68.18%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 3693
            +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  326 DGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 391          
BLAST of TTF-type domain-containing protein vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 65.4698 bits (158), Expect = 1.274e-10
Identity = 29/66 (43.94%), Postives = 45/66 (68.18%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 3693
            +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  343 DGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 408          
BLAST of TTF-type domain-containing protein vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 65.4698 bits (158), Expect = 1.296e-10
Identity = 29/66 (43.94%), Postives = 45/66 (68.18%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 3693
            +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  350 DGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 415          
BLAST of TTF-type domain-containing protein vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 65.4698 bits (158), Expect = 1.394e-10
Identity = 29/66 (43.94%), Postives = 45/66 (68.18%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 3693
            +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  400 DGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 465          
BLAST of TTF-type domain-containing protein vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0074100)

HSP 1 Score: 72.7886 bits (177), Expect = 5.186e-13
Identity = 33/79 (41.77%), Postives = 51/79 (64.56%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 3732
            NN   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  290 NNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 367          
BLAST of TTF-type domain-containing protein vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0308132)

HSP 1 Score: 72.7886 bits (177), Expect = 5.186e-13
Identity = 33/79 (41.77%), Postives = 51/79 (64.56%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 3732
            NN   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  290 NNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 367          
BLAST of TTF-type domain-containing protein vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0074101)

HSP 1 Score: 72.7886 bits (177), Expect = 5.186e-13
Identity = 33/79 (41.77%), Postives = 51/79 (64.56%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 3732
            NN   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  290 NNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 367          
BLAST of TTF-type domain-containing protein vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0308130)

HSP 1 Score: 72.7886 bits (177), Expect = 5.186e-13
Identity = 33/79 (41.77%), Postives = 51/79 (64.56%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 3732
            NN   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  290 NNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 367          
BLAST of TTF-type domain-containing protein vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0340115)

HSP 1 Score: 72.7886 bits (177), Expect = 5.291e-13
Identity = 33/79 (41.77%), Postives = 51/79 (64.56%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 3732
            NN   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  295 NNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 372          
BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Match: CR762475.1 (pep chromosome:GRCz11:4:55494751:55498830:1 gene:ENSDARG00000098243.2 transcript:ENSDART00000172605.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR762475.1)

HSP 1 Score: 107.457 bits (267), Expect = 1.045e-24
Identity = 88/293 (30.03%), Postives = 141/293 (48.12%), Query Frame = 2
Query:  176 CKLFNKN----SSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAW-----KELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHL-CIVKNQDIM----VHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQ 1009
            C++F +     + +  + LG N W+     +  H     H+ +   W     K L  +     T D   +   + E Q  R+IL RLI +   LA Q  AFRG +E   + N GNF + V+ LA +D V+ +HL  I + Q  M    V  L    QN ++  L   I++KI + +K  + +SI+LD T DVSH E ++ ++R+V  ++            ++E FL    LE TTG  +   +I  L+   L ++N+RGQ Y+  +NM G  KG+  +   H   +L+   Q
Sbjct:  227 CRIFLREEKFKNKTAWKTLGINTWRSATGKMKEHASTEAHMMSMVRWNIYSKKALQTAFD---TSDIQGKAIRERERQRNREILTRLIDISLYLARQGQAFRGDDESSSSANQGNFIELVKTLAQYDSVMKLHLDAIQEKQASMKKPQVSLLSNRSQNDIIMSLGTFIRSKIQNEIKEAQIFSILLDETTDVSHKEQVSFVVRYVRDME------------VKERFLQVCTLESTTGKELENVVISLLQDNGLDLKNIRGQGYDGAANMSGMYKGLQSRIRAHNEKALYVHCQ 504          

HSP 2 Score: 27.335 bits (59), Expect = 1.045e-24
Identity = 9/18 (50.00%), Postives = 11/18 (61.11%), Query Frame = 1
Query:  115 RSWLIYSTIKDTVFCFFC 168
            R WL YS   D ++CF C
Sbjct:  210 RPWLEYSPKNDAIYCFSC 227          

HSP 3 Score: 64.3142 bits (155), Expect = 9.158e-10
Identity = 57/228 (25.00%), Postives = 103/228 (45.18%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTS-------HIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFD-DPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETE-AKFEPDECRRRRYKRQFEYEA 1616
            Q+ I   N +A ++ C AH LNLV  +++K  +    FFSLV++++ + + ST+R   F            ++ ++ LS+TRW  R    K     L  +   L D+ + DP        T+  DAK    AI  F+F++       +     V S  LQK+D  +++         + +   RS+  F+ +   A E A+++  +     P   R+R+   ++ + A
Sbjct:  488 QSRIRAHNEKALYVHCQAHCLNLVLVESAKSSIHFVTFFSLVEKLYVFCTGSTKRHTAFLKCQQSLYPGQRVVELQKLSDTRWACRERSLKALNKVLKALIKLLTDLCESDP------PETAAGDAKMYLRAI-DFEFLLCSEITTTVFQITGVASDALQKKDLDLSTAYTITDGVLDTVKNLRSEEEFKTIFQKAVEKAEDVGIDIPTVPPGHGRKRKVPTRYLHSA 708          
BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Match: tead3a (TEA domain family member 3 a [Source:ZFIN;Acc:ZDB-GENE-031112-10])

HSP 1 Score: 67.781 bits (164), Expect = 3.928e-11
Identity = 30/80 (37.50%), Postives = 48/80 (60.00%), Query Frame = 1
Query: 3511 FVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            + +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   +T+E LLC+ ++F V+  D G     QY +Y +V +
Sbjct:  330 YRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSDHG----AQYHVYRLVKD 405          
BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Match: tead3a (TEA domain family member 3 a [Source:ZFIN;Acc:ZDB-GENE-031112-10])

HSP 1 Score: 67.781 bits (164), Expect = 3.970e-11
Identity = 30/80 (37.50%), Postives = 48/80 (60.00%), Query Frame = 1
Query: 3511 FVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            + +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   +T+E LLC+ ++F V+  D G     QY +Y +V +
Sbjct:  334 YRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSDHG----AQYHVYRLVKD 409          
BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Match: tead3b (TEA domain family member 3 b [Source:ZFIN;Acc:ZDB-GENE-080103-3])

HSP 1 Score: 66.6254 bits (161), Expect = 9.029e-11
Identity = 29/80 (36.25%), Postives = 48/80 (60.00%), Query Frame = 1
Query: 3511 FVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            + +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   ET+E LLC+ ++F V+  + G     QY +Y ++ +
Sbjct:  327 YRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRETQETLLCIAFVFEVSTSEHG----AQYHVYRLIKD 402          
BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Match: tead1a (TEA domain family member 1a [Source:ZFIN;Acc:ZDB-GENE-040426-2101])

HSP 1 Score: 60.8474 bits (146), Expect = 6.134e-9
Identity = 29/85 (34.12%), Postives = 47/85 (55.29%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   ET+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:  342 NGRFVYKISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVSNRETQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 422          
BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000043220.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:7:36411169:36451375:1 gene:ENSXETG00000018966.1 transcript:ENSXETT00000043220.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 128.642 bits (322), Expect = 1.171e-29
Identity = 84/274 (30.66%), Postives = 141/274 (51.46%), Query Frame = 2
Query:  221 GSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDI-MVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL 1036
            G N+WK   V L+ HE + FH D +   +     IS    ID +  +   +E +YWR +L+R++  ++ L+++ L FRGT+EK  +  NGN+   +E +A  DP +  H+    N       YL K +    + I+A ++   I++  K  KYYSI +DSTPDVSH + +  II +V   K  G        I +E F+ F+P        +   +++ LK+  + I + RGQ Y+N SNM G   G+  +  +  P +++  + C+   L+ +
Sbjct:   98 GYNDWKNASVRLNEHEESKFHKDCYLRMQN-RAKISGR--IDQLFLEKQNQEMEYWRNVLKRVVTAVKTLSSRGLPFRGTDEKFGSLTNGNYLMLLEAIAEHDPFLAEHIKKYGNTGTGSTSYLSKTVCFEFIDIVASSVLEVIINEAKQAKYYSISVDSTPDVSHTDQLAFIICYV---KNDG--------IPKERFIKFIPNVGHKAENLFSAVMDTLKEYHIDILDCRGQSYDNASNMSGPYSGLQARIKQVNPLAVY--IPCSAHSLNLV 355          

HSP 2 Score: 95.9005 bits (237), Expect = 2.389e-19
Identity = 67/221 (30.32%), Postives = 116/221 (52.49%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHI--VILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDECRRRRYKRQFEYEA 1616
            Q  I  +N  A +IPC+AHSLNLV   A++ C EA +FF ++QQ++++FSAS+ RW +  SH+      VK LS TRW +R D    +                     NSS + S + A++L   +  F F+ +L  W  IL++V+  ++ LQ +  +I   +K +   ++   + R  +  +++   A ++ ++LE  A F   + R+R+ K +  YE+
Sbjct:  332 QARIKQVNPLAVYIPCSAHSLNLVGTSAAESCREAVSFFCILQQLYHFFSASSTRWEMLISHLKRKATVVKNLSTTRWSARSDAYIRE---------------------NSSNSDSVSTAQSLLLQV-DFHFLCTLFVWNKILSQVDRDNQALQAKSISILDASKIVNGLRSTFQEMRVIS-VDEIYFYARDVCEKLEIPATFP--QKRKRKVKARASYES 527          

HSP 3 Score: 68.1662 bits (165), Expect = 7.326e-11
Identity = 43/99 (43.43%), Postives = 58/99 (58.59%), Query Frame = 1
Query: 1789 LTDCKHLETSLTHKENKDIDAYDLCN*L-----QVVQRLP--KPMSPSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            L+  +   + L  K +KD+DA +LC+ +     QV   LP  K  +P D+   I      DC PN+  + RI LT PV+VAS K SFSKLKLIK+YLR+
Sbjct:  582 LSQLQKAASDLALKYSKDLDASELCSEIESFRHQVEAILPDAKSATPLDLCQMIQDYSLADCYPNIDTAFRIFLTSPVTVASCKRSFSKLKLIKNYLRS 680          
BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Match: tbx18 (T-box 18 [Source:Xenbase;Acc:XB-GENE-489907])

HSP 1 Score: 75.0998 bits (183), Expect = 4.770e-13
Identity = 61/225 (27.11%), Postives = 107/225 (47.56%), Query Frame = 2
Query:  365 IKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYNNNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDI-IKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL 1036
            +K + +  R+ L  +++ I    T ++A RG      + +GN        AL+D        I    +I+ ++L     N L+      ++ +I+S   ++  +S+I D + D+S  E +++ +RFVD+ I P         V IRE FLGF  L+      I   ++E+  +  L I+ L GQ Y+  S M GKE GV  +  +  P ++F  + C   KL+ +
Sbjct:   65 VKHQVEENRKKLYSVLSTIVFCGTHDIALRGKT----STSGNVQ------ALYD------FRIESGDEILKNHLKNAPVNALL--CEDILRERIISAANNSVGFSVIADESADISGHEQLSLGVRFVDLTITP---------VKIREEFLGFATLKAFDATSIANVIMEQCIKFGLNIDKLYGQGYDGCSTMAGKEGGVQAKIKEKYPRAIF--VHCASHKLNLV 260          
BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Match: slc10a6 (solute carrier family 10 (sodium/bile acid cotransporter), member 6 [Source:Xenbase;Acc:XB-GENE-988401])

HSP 1 Score: 72.7886 bits (177), Expect = 2.426e-12
Identity = 68/260 (26.15%), Postives = 118/260 (45.38%), Query Frame = 2
Query:  263 HERNTFHLDNFQ-AWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYNNNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDI-IKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL 1036
            H   T H   +  A   ++V    E++I       +K + +  R+ L  +++ I    T ++A RG      + +GN        ALFD       CI    +I+ ++L     N      +  ++N+++ L      +S+I D + D+S  E +++ +RFVD+ I P         V IRE FLGF  L+      I   ++E+  +  L ++ L GQ Y+  S M GKE GV  +  +  P ++F  + C   KL+ +
Sbjct:   84 HSLTTCHKQAYDDATNFINVRSHPEQSIVCQVNSAVKHQVEENRKKLYSVLSTIVFCGTHDIALRGKT----STSGNVQ------ALFD------FCIESGDEILKNHLKNAPVNARY--TSVRVENELIVLSG----FSVIADESADISGHEQLSLGVRFVDLTITP---------VKIREEFLGFATLKAVDATSIANVIMEQCIKFGLNMDKLYGQGYDGCSTMAGKEGGVQAKIKEKYPRAIF--VYCASHKLNLV 310          
BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106])

HSP 1 Score: 69.707 bits (169), Expect = 1.162e-11
Identity = 33/79 (41.77%), Postives = 48/79 (60.76%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 3732
            N    + +   PMC+YL   + +LKQ  +K  MNSVLENF++ Q V   +T+E+LLC+ Y+F V+  + G   H  YRL
Sbjct:  317 NGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHI-YRL 394          
BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106])

HSP 1 Score: 69.3218 bits (168), Expect = 1.210e-11
Identity = 33/79 (41.77%), Postives = 48/79 (60.76%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 3732
            N    + +   PMC+YL   + +LKQ  +K  MNSVLENF++ Q V   +T+E+LLC+ Y+F V+  + G   H  YRL
Sbjct:  292 NGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHI-YRL 369          
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Tead2 (TEA domain family member 2 [Source:MGI Symbol;Acc:MGI:104904])

HSP 1 Score: 67.781 bits (164), Expect = 7.511e-13
Identity = 31/74 (41.89%), Postives = 47/74 (63.51%), Query Frame = 1
Query: 3529 PMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            PMC+YL   L +L+Q  ++  MNSVLENF++ Q V   +T+E+LLC  Y+F V+  + G     QY +Y +V +
Sbjct:   60 PMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERG----AQYHIYRLVRD 129          
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Tead2 (TEA domain family member 2 [Source:MGI Symbol;Acc:MGI:104904])

HSP 1 Score: 68.5514 bits (166), Expect = 2.537e-11
Identity = 31/74 (41.89%), Postives = 47/74 (63.51%), Query Frame = 1
Query: 3529 PMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            PMC+YL   L +L+Q  ++  MNSVLENF++ Q V   +T+E+LLC  Y+F V+  + G     QY +Y +V +
Sbjct:  341 PMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERG----AQYHIYRLVRD 410          
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Tead2 (TEA domain family member 2 [Source:MGI Symbol;Acc:MGI:104904])

HSP 1 Score: 68.5514 bits (166), Expect = 2.796e-11
Identity = 31/74 (41.89%), Postives = 47/74 (63.51%), Query Frame = 1
Query: 3529 PMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            PMC+YL   L +L+Q  ++  MNSVLENF++ Q V   +T+E+LLC  Y+F V+  + G     QY +Y +V +
Sbjct:  376 PMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERG----AQYHIYRLVRD 445          
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Tead2 (TEA domain family member 2 [Source:MGI Symbol;Acc:MGI:104904])

HSP 1 Score: 68.5514 bits (166), Expect = 2.796e-11
Identity = 31/74 (41.89%), Postives = 47/74 (63.51%), Query Frame = 1
Query: 3529 PMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            PMC+YL   L +L+Q  ++  MNSVLENF++ Q V   +T+E+LLC  Y+F V+  + G     QY +Y +V +
Sbjct:  376 PMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERG----AQYHIYRLVRD 445          
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym1 (zinc finger, MYM domain containing 1 [Source:MGI Symbol;Acc:MGI:1915560])

HSP 1 Score: 66.6254 bits (161), Expect = 1.838e-10
Identity = 57/278 (20.50%), Postives = 125/278 (44.96%), Query Frame = 2
Query:  221 GSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLA-----LFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL 1036
            G+ +W+ +      HE +  HL + Q W++     +      ++  + I+  ++Y R I+E ++     L  Q L  +G ++ +   N G+F + +E  A     +F  +++ H+           Y    +Q  ++ ++   +   I+S + ++  +SII +     +    +++ +R+         +    AV+++E FLGFV  EE TG  +   +   L+Q+ +    + GQ Y++ +N   K   V  +  K +P +L+      F +L+ +
Sbjct:  243 GTADWEKMLGNFRKHEESDVHLKSLQFWRQYQFLDAIPCDNSSVYSKQIEGNKKYLRLIIENIL----FLGKQCLLLKGNDQSVSPMNKGSFLELLELRARDRGEVFQ-LMSSHV---------DFYSSTLVQEEIIEMIKDEMLQDIVSEINASSAFSIICEEIAGSAAERQLSVCVRY--------PQKTPSAVLVKERFLGFVTAEEVTGVHVHGRIKAYLQQVGVDFNKICGQAYDSATNFTVKLNEVVAEFKKEEPRALYVHCHAHFLELAVI 498          
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5SVZ6|ZMYM1_HUMAN (Zinc finger MYM-type protein 1 OS=Homo sapiens OX=9606 GN=ZMYM1 PE=1 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 2.990e-16
Identity = 71/276 (25.72%), Postives = 137/276 (49.64%), Query Frame = 2
Query:  221 GSNEWKIIGVILSSHERNTFHLDNFQAWKE---LDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL 1036
            G++ WK        HE++  HL + + W+E    D ++S + +   I+ + I+  ++Y + I+E ++     L  Q L  RG ++ + + N GNF + +E  A         L  + +Q  +  Y    IQ+ ++ I+   +   I++ +  +  +SII D T + +  E ++I +R+     P  S     A++I+E FLGFV  EE TG  +  T+   L+Q+ + ++ + GQ Y++ +N+K K   +  +  K +P +L+      F  LS +
Sbjct:  499 GTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQFCDGAVSDDLS---IHSKQIEGNKKYLKLIIENIL----FLGKQCLPLRGNDQSVSSVNKGNFLELLEMRAKDKGEETFRL--MNSQ--VDFYNSTQIQSDIIEIIKTEMLQDIVNEINDSSAFSIICDETINSAMKEQLSICVRY-----PQKS---SKAILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSII 755          
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|P30052|SCAL_DROME (Protein scalloped OS=Drosophila melanogaster OX=7227 GN=sd PE=1 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 8.662e-12
Identity = 33/79 (41.77%), Postives = 51/79 (64.56%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 3732
            NN   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  360 NNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 437          
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q25214|SCAL_JUNCO (Protein scalloped (Fragment) OS=Junonia coenia OX=39708 GN=SD PE=2 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 1.337e-11
Identity = 33/98 (33.67%), Postives = 56/98 (57.14%), Query Frame = 1
Query: 3460 KSII*IIDHSTANNEMG---FVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIV 3744
            K ++  ++   A NE G   + ++  PMC+Y+   + +LK   +K  MNSVLENF++ Q V   +T+E LLC  ++F V+  + G     Q+ +Y +V
Sbjct:   41 KQVVEKVETEYARNEGGRFVYRIQRSPMCEYMVNFIHKLKHLPEKYMMNSVLENFTILQVVSNRDTQETLLCAAFVFEVSNSEHG----AQHHIYRLV 134          
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UJ78|ZMYM5_HUMAN (Zinc finger MYM-type protein 5 OS=Homo sapiens OX=9606 GN=ZMYM5 PE=1 SV=4)

HSP 1 Score: 53.9138 bits (128), Expect = 2.999e-11
Identity = 22/37 (59.46%), Postives = 28/37 (75.68%), Query Frame = 1
Query:   58 RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            R+FS  +Y R L NGE+  RSWL+YST KD+VFC +C
Sbjct:  557 RKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYC 593          

HSP 2 Score: 38.5058 bits (88), Expect = 2.999e-11
Identity = 18/57 (31.58%), Postives = 31/57 (54.39%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTID 346
            CKLF +  + +  + G  +W+ +  ILS HE +  H++N   + +L   + K K ID
Sbjct:  593 CKLFGEGKNQLKNENGCKDWQHLSHILSKHEESEMHVNNSVKYSKLKSDLKKNKAID 649          
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4R3D6|ZMYM5_MACFA (Zinc finger MYM-type protein 5 OS=Macaca fascicularis OX=9541 GN=ZMYM5 PE=2 SV=3)

HSP 1 Score: 53.9138 bits (128), Expect = 5.661e-11
Identity = 22/37 (59.46%), Postives = 28/37 (75.68%), Query Frame = 1
Query:   58 RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            R+FS  +Y R L NGE+  RSWL+YST KD+VFC +C
Sbjct:  554 RKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYC 590          

HSP 2 Score: 37.7354 bits (86), Expect = 5.661e-11
Identity = 17/57 (29.82%), Postives = 31/57 (54.39%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTID 346
            C+LF +  + +  + G  +W+ +  ILS HE +  H++N   + +L   + K K ID
Sbjct:  590 CRLFGEGKNQLKNENGCKDWQHLSHILSKHEESEMHINNSVKYSKLKSDLKKNKAID 646          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: R4G9H6 (TTF-type domain-containing protein OS=Anolis carolinensis OX=28377 GN=LOC103280065 PE=4 SV=1)

HSP 1 Score: 211.846 bits (538), Expect = 4.911e-135
Identity = 106/265 (40.00%), Postives = 165/265 (62.26%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQ 967
            CK+F  ++SS+    G + W+ +  +LSSHE++  H++N  +W+EL   +   KTID  +++ I  E ++W QIL+RL+   R L  Q L FRGT + L+  NNGNF K +E++A FD  +  H+  + +++  VHYL K +QN  +  LA  ++N IL  +    YYSIILD TPD+S+ E MT+++RFV              ++I+EHFLGFVP+   +G  +TE L+ +L+   + ++N+RGQ Y+NGS MKGK  GV ++
Sbjct:  225 CKIFGNDTSSLAGSQGFSNWRNLSRLLSSHEKSRPHMENRSSWRELSQRLHLNKTIDAEHERLINAEIKHWDQILKRLLCATRFLGVQGLPFRGTKDVLFEPNNGNFLKLIEHIAQFDDPMAEHVRRITSKETHVHYLSKNVQNEFISFLAGKVQNNILEQLHEATYYSIILDCTPDISNTEQMTLVVRFVTCKA-------NEDILIKEHFLGFVPVASPSGEGMTEILLHELEARRIPLKNMRGQGYDNGSAMKGKHVGVQRR 482          

HSP 2 Score: 166.777 bits (421), Expect = 4.911e-135
Identity = 84/221 (38.01%), Postives = 131/221 (59.28%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPD-ECRRRRYKRQFEYEAQ 1619
            Q  IL++N +AF++PC  HSLNLV  DA+  C  A + F+ VQ ++N FS S  RW     H+  LT+KPLS TRWESRI+   P R+ +  +YD + +   D + +       R+ A AL   +  F F+ S+VTW+ IL+++N+ SK LQK    + +    ++  K++L + RS+ G   ++ DA E+A++++  A FE + E R R+  RQF YE +
Sbjct:  480 QRRILDLNPRAFYVPCGNHSLNLVINDAAMSCKIAADCFATVQDLYNLFSGSPVRWGTLLKHVSTLTLKPLSSTRWESRIEALLPLRFHIEEVYDAVYEASHDQKFD----GLCRSRAGALLKRLQSFTFLCSIVTWHEILHKINIVSKQLQKVSIDLQNSMALIKSVKSFLERMRSEEGLNSIITDAKELAEKIDATADFENEQEARPRKVSRQFSYECK 696          

HSP 3 Score: 122.865 bits (307), Expect = 4.911e-135
Identity = 72/157 (45.86%), Postives = 98/157 (62.42%), Query Frame = 1
Query: 1600 SLNMKLKAPQDPKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINK-KTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPMS-PSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            S   K +A    K   KV F + + D AI S++ERFQ ++ H   F F+YDIS++ K     ++   C+ LET LT  E+ D++A DL   LQ++  +  P S P+D L +I     ED  PNV  +LRILLTLP+SVASG+ SFSKLKLIK+YLR+
Sbjct:  692 SYECKDEAVHSGKESFKVNFFFVVLDTAISSLKERFQLMDNHSGSFKFLYDISSLGKCWNEKELKYACQRLETVLTDGEDHDVNAGDLYTELQLLADMLPPGSLPADALSFI-NHGSEDVFPNVYTALRILLTLPISVASGERSFSKLKLIKNYLRS 847          

HSP 4 Score: 56.225 bits (134), Expect = 4.911e-135
Identity = 23/39 (58.97%), Postives = 26/39 (66.67%), Query Frame = 1
Query:   52 NNRRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            + R+FSP HY RKL NGE V R WL YS  K+ VFC  C
Sbjct:  187 HGRKFSPFHYSRKLCNGERVNRYWLQYSVSKNAVFCITC 225          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: H9GS44 (TTF-type domain-containing protein OS=Anolis carolinensis OX=28377 GN=LOC103281749 PE=4 SV=2)

HSP 1 Score: 166.777 bits (421), Expect = 2.112e-118
Identity = 87/221 (39.37%), Postives = 135/221 (61.09%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPD-ECRRRRYKRQFEYEAQ 1619
            Q  IL++N +AF++PC  HSLNL+  DA   C  A N F+ +QQI ++FS+STQ+W +   H+  LTVKP   TRWESRI+   P R+ +  +YD L + +++   +  S  +SR  A AL   +  F+F+  LVTW+ IL+++N  SK+L K  + + S    ++  K++L + RSD G   V+IDA E+A++++  A FE +   R R   RQ  YE++
Sbjct:  595 QRRILDLNPRAFYVPCGNHSLNLLLNDAVLSCSIAANCFNTIQQIFSFFSSSTQKWCILLKHVPTLTVKPFCNTRWESRIEALLPLRFHIEEVYDALYEAYEEQIFDGYS--SSR--AAALLKQLQSFRFLCCLVTWHEILHKINRVSKLLPKVTNDLQSSMDLIKSVKSFLERMRSDQGLNSVIIDAKELAEKIDVAADFEKELPARPRNVNRQISYESK 811          

HSP 2 Score: 162.54 bits (410), Expect = 2.112e-118
Identity = 91/265 (34.34%), Postives = 151/265 (56.98%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQ 967
            CK+F   +S +    G ++W+ +   L+SHE +  H+ N  +W EL V +   KT    +++ I  E +  +Q L RL+ +  +L  Q LAF    +  + +N GNF K VE +A    V+  H+  + +++  VH L + +QN  +  L+  I++ IL  +   KYYSIILD TPD SH E MT+++RF+ I         +  V I+EHFLGFVP+  ++   +TE L+++L+   + ++++RGQ Y+  S MKGK  G+ ++
Sbjct:  342 CKVFGNTNSPLASSQGDSDWQNLAETLASHETSHIHMKNRASWHELSVRLQLNKTTVAEHERLIHAETE--QQDLTRLLCVAEILGAQGLAFLEEKDVPFEHNGGNFFKLVEQIAKLAGVMAEHVRRINSKETHVHCLNESVQNKFVSFLSAKIQDNILQQLCQAKYYSIILDCTPDASHTEQMTLMVRFIKIEG-------KKEVSIKEHFLGFVPVTHSSDEDLTEILLQELEARGIPLKSMRGQAYDCDSAMKGKHVGLQRR 597          

HSP 3 Score: 113.235 bits (282), Expect = 2.112e-118
Identity = 66/157 (42.04%), Postives = 96/157 (61.15%), Query Frame = 1
Query: 1600 SLNMKLKAPQDPKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKK-TSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPMS-PSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            S   K +A    K   KV F + + D AI  ++ERF+ +E H   F F+YDIS++ K    T++   C+HL+T L+  E+ D++  DL + LQ+   L  P S P++ L +I ++      PNV  +LRILLTLPVS+AS + SFSKLKLIK+YL +
Sbjct:  807 SYESKDEAVHSDKDSFKVNFFFVVLDTAISLLKERFELMENHSKNFKFLYDISSLGKSLNETELKNACQHLQTVLSDGEDCDVNGDDLFDELQIFAHLLPPGSHPAEALSFITKRGLVATFPNVYNALRILLTLPVSMASSERSFSKLKLIKTYLSS 963          

HSP 4 Score: 59.3066 bits (142), Expect = 2.112e-118
Identity = 23/36 (63.89%), Postives = 28/36 (77.78%), Query Frame = 1
Query:   61 RFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            RF+  HYKRKL NGE V+R WL+YS +K+ VFCF C
Sbjct:  307 RFTSNHYKRKLCNGEHVHRVWLLYSVLKNAVFCFAC 342          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: G1KXP1 (Uncharacterized protein OS=Anolis carolinensis OX=28377 PE=4 SV=1)

HSP 1 Score: 201.83 bits (512), Expect = 2.206e-118
Identity = 107/264 (40.53%), Postives = 164/264 (62.12%), Query Frame = 2
Query:  179 KLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQ 967
            K+F    S      G ++W  +G +L+SHE++  H+ N  +W EL   +  +KTID  +++ I  E ++W+Q+L+RL+ ++R L  Q LAFRGT + L+  +NGNF K VE++A FD  +  H+  V +++  VHYL K +QN  +  LA  I+N IL  +    YYSIILD T D+S+ E MT+++RFV        E  E A  I+EHFLGFVP+   +G  +TE L+++L+   + ++N+RGQ Y+NGS MK K  GV ++
Sbjct:    1 KIFGNAKSVFASSQGYSDWSNLGKLLTSHEKSRTHIKNHASWHELSQHLHLKKTIDAEHERLIYGESKHWQQVLKRLLCIVRFLGVQGLAFRGTKDVLFEPDNGNFLKLVEHIAQFDDPMAEHVRRVSSKETHVHYLSKNVQNEFIAFLAGKIQNNILQQLHEATYYSIILDCTTDISNTEQMTLVVRFVKC------EANEDAS-IKEHFLGFVPVANPSGEGLTEILLKELEARHIPLKNMRGQGYDNGSAMKRKHVGVQRR 257          

HSP 2 Score: 159.458 bits (402), Expect = 2.206e-118
Identity = 85/226 (37.61%), Postives = 127/226 (56.19%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDEC-RRRRYKRQFEYEAQGTTRS 1634
            Q  IL++N +AF++PC  HSLNLV  DA+  C  A   F+ +Q ++N FS+S  RW +   H+  LT+KPLS TRWESRI+   P RY +  +YD L +     + +       +T A AL   +  F F+ SLVTW+ ILN++N+ SK +QK    + S    ++  K +L + RS+ G   V+ DA E+A +++  + FE +   R R+  RQF      T  S
Sbjct:  255 QRRILDLNPRAFYVPCGNHSLNLVVNDAALSCSIAAECFTTIQDLYNVFSSSPLRWSILLKHVSTLTLKPLSNTRWESRIEALLPLRYHIEEVYDALYEASQCQKFD----GYYKTHAVALLKRLQSFTFLCSLVTWHEILNKINMVSKQMQKVTIDLQSSMDLIKSVKTFLERMRSEEGLNSVITDAKELAGKIDATSDFEKEPLPRPRKVSRQFSLGPDKTVHS 476          

HSP 3 Score: 119.013 bits (297), Expect = 2.206e-118
Identity = 67/151 (44.37%), Postives = 96/151 (63.58%), Query Frame = 1
Query: 1618 KAPQDPKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINK-KTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPMS-PSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            K     K   KV F + + D AI S+EERF+ ++ H   F F+YDIS++ K     ++   C+HL+T LT  E+ D++  +L + LQ++  +  P S P++ L +I     ED  PNV  +LRILLTLP+SVASG+ SFSKLKLIK+YLR+
Sbjct:  472 KTVHSGKDSFKVNFFFVVLDTAISSLEERFELMDNHTESFKFLYDISSLGKCLNDKELKNACQHLQTVLTDGEDHDVNGDNLYDELQILANMLPPRSLPAEALSFI-NCGLEDTFPNVYIALRILLTLPISVASGERSFSKLKLIKNYLRS 621          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: H3A856 (TTF-type domain-containing protein OS=Latimeria chalumnae OX=7897 PE=4 SV=1)

HSP 1 Score: 239.195 bits (609), Expect = 3.068e-112
Identity = 119/264 (45.08%), Postives = 174/264 (65.91%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPK 964
            CK+F  N  S L   G  +WK +  ILSSHE++  H+  FQ WKE++  ++  KT+D  N++ +  E ++WR +L RL+AL R LA QNL F+G +++LY   NGNF KF+E + +FD V+   L  + + D  +HYLGK IQN L+ +LA  I+ KILS+VK +KYYS+ILD   D+SH+E + +I+RFV   +P   E       I+E FL FV L++++G  +TE L++KL +M L + ++RGQ Y+NG+NMKGK K V K
Sbjct:  173 CKIFTLNVKSALASDGVRDWKNLSAILSSHEKSFDHISAFQTWKEMEERLNCNKTVDQYNRRTLSAETEHWRNVLHRLVALTRTLAVQNLTFQGHSDRLYEPGNGNFLKFIELMGMFDGVMKERLQRITSNDTHIHYLGKNIQNELIDLLASKIRGKILSMVKESKYYSVILDCMLDISHMEQIAMIVRFVS-TRPGNVE-------IQECFLAFVKLDDSSGEGMTEVLLQKLNEMGLPLADMRGQSYDNGANMKGKNKEVQK 428          

HSP 2 Score: 155.992 bits (393), Expect = 3.068e-112
Identity = 85/220 (38.64%), Postives = 130/220 (59.09%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDECRRRRYKRQFEYEAQ 1619
            Q  +  +N +AFF+PCN HSLNL+  DA+ CC +A NF  ++Q I  YFS ST +W +   H+V    K LSETRW SR++ ++  RY      D L+ I DD  L  + G  S  +A+++   +  FKF+ SLV W++IL EVN+ SK LQ  +  ++   +QL V +++L   R D+ F  VL  A E+A+ L  + +F  +E ++   K QF+Y+ +
Sbjct:  427 QKWVRELNSRAFFVPCNTHSLNLILSDAAGCCTDAVNF-GVIQAIFVYFSLSTYQWDILLKHVV----KQLSETRWGSRVEAARAIRY------DALLSIADDTMLTGTCGTKSHAEARSITGKVLNFKFLCSLVVWHDILFEVNIASKTLQVVEFDLHQAIEQLAVLQDFLQNYRLDHSFVSVLAIAQELAESLSIQQRF-AEEIQK---KTQFDYKTR 631          

HSP 3 Score: 55.8398 bits (133), Expect = 3.068e-112
Identity = 22/40 (55.00%), Postives = 28/40 (70.00%), Query Frame = 1
Query:   49 SNNRRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            + NR+F+P HY   L NGE V R+WL+YS   DT+FCF C
Sbjct:  134 TGNRKFTPNHYMHHLTNGEAVARTWLLYSVSSDTIFCFCC 173          

HSP 4 Score: 30.4166 bits (67), Expect = 3.068e-112
Identity = 19/73 (26.03%), Postives = 36/73 (49.32%), Query Frame = 1
Query: 1648 KVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN 1866
            K +F Y   D  + + E+ F+        F  +Y I  ++  +   +   C  L+++L   ++KDIDA +LC+
Sbjct:  623 KTQFDYKTRDEPVVNPEQSFKV-----NFFYVLYKIPELSSSSHEVLFEQCTDLQSALMDGDSKDIDASELCD 690          
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: A0A5N4B4G4 (Uncharacterized protein OS=Photinus pyralis OX=7054 GN=PPYR_01413 PE=4 SV=1)

HSP 1 Score: 201.83 bits (512), Expect = 2.453e-110
Identity = 112/266 (42.11%), Postives = 161/266 (60.53%), Query Frame = 2
Query:  176 CKLFNK----NSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRG-TNEKLYNNNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGV 958
            CK+FN       +S +  +GSN+W    + L  H  +  H+++F  W +L   +    TID +NQ+ +  E+ +WR++L R+IA++R LA  N AFRG +N     +NGNF K +E +  FD  +  HL  +++++  VHYLG  IQN L+ +L  A KNKIL  V+  KYYS+ILD TPD SH E ++  IR+V+I K       +P  I+ E F+ F+ + ++TG  ITE L   LK+  L I N RGQ Y+NGSNMKGK KGV
Sbjct:  178 CKVFNVGLNVTQASKMCSVGSNDWHNFSIKLQQHNSSKEHVESFVKWVDLKERLGTRSTIDAVNQKLLNMEKDHWRKVLYRIIAVVRYLAETNSAFRGRSNVPFDKHNGNFLKLIEMIGTFDDPMKEHLRRIRDEETRVHYLGSDIQNELIGLLGEATKNKILDEVRIAKYYSVILDCTPDKSHKEQISFSIRYVNITK-------DPPEIV-ERFVEFLDITDSTGEGITEVLKILLKKNGLDIMNCRGQAYDNGSNMKGKNKGV 435          

HSP 2 Score: 139.043 bits (349), Expect = 2.453e-110
Identity = 76/212 (35.85%), Postives = 121/212 (57.08%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDECRRRRYK 1595
            Q+ +L IN +A +I C AH LNL   D SK    A  FF ++Q++   FS+STQRW +   +   LT+KP S TRWESR++  KP RYQLG + D L ++      N ++   + ++A +L   I  F+F++SL+ WY++L+  N+ SK+LQ ED  ++    +L     +L   R ++GF   L  A ++  EL+ + + +    R+ R K
Sbjct:  436 QSRVLEINKRAIYIACPAHELNLALCDMSKSVPLAMTFFGVIQRLFTLFSSSTQRWSILLKYCTNLTLKPHSTTRWESRLESVKPIRYQLGNVSDALNEL-----ANTTNEPLTNSEATSLKSHIISFEFVLSLIIWYDLLHAFNIVSKLLQSEDMKLDVALNELNGLTTFLEHYR-ESGFAAALKTAKDLIAELDLQEEPKFAVTRKSRNK 641          

HSP 3 Score: 81.6481 bits (200), Expect = 2.453e-110
Identity = 58/202 (28.71%), Postives = 109/202 (53.96%), Query Frame = 1
Query: 1594 NGSLNM-KLKAPQD-PKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQR-LPKPMSPSDV---LLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRTCGLSNNFNRM*L-------RFEIGIEGISRNFCEEEGKK 2160
            N +LN  +++ PQ+  K+  +  +   + D+AI++++ RF +L+++  LF FI+DI  + + + TD+   C  L  +     ++D+D   L   L + +  +P  +  +      LY +++ +    PN+  + R+LLT+PV+VAS + SFS+LKLI +YLR+       N + +         EI IE +  NF  ++ +K
Sbjct:  640 NKNLNANEIEDPQEHAKNIFRTTYFLAVVDVAIRNMQCRFSELKKYAELFEFIFDIQKLQQMSETDLQASCNKLADAFQDGLSQDLDRNGLFAELNIFKHTVPDKIDSALAALNYLYPIRESY----PNLTIAYRLLLTIPVTVASAERSFSRLKLIINYLRSTMTEQRLNGLAILSIESEVAQEIDIEELIDNFAAKKARK 837          

HSP 4 Score: 52.373 bits (124), Expect = 2.453e-110
Identity = 24/45 (53.33%), Postives = 27/45 (60.00%), Query Frame = 1
Query:   49 SNNRRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFCGFLQV 183
            SN R+FSP   K KL NGE   R+WLIYS  KD  +CF C    V
Sbjct:  139 SNKRQFSPKWRKFKLVNGEVCERTWLIYSKTKDLAYCFCCKVFNV 183          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000025204.2 (pep primary_assembly:Astyanax_mexicanus-2.0:12:7364240:7371214:-1 gene:ENSAMXG00000024490.2 transcript:ENSAMXT00000025204.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 190.66 bits (483), Expect = 2.957e-106
Identity = 101/262 (38.55%), Postives = 160/262 (61.07%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGV 958
            C +  K  ++ L   G ++WK +   L  HE +  H DN + W EL   +  + TID   Q  ++ E ++W+ ++ R+IA+I  LA +N A RGT   LY+ +NGNF   VE +A FDPV+N H+   +NQ+  VHYL   IQN ++ +    I NK+L  + + + YS+I+D TPD+SH E +++++R V+          +P+V I EHF GF+ +E+T+G  +TE L++ L++  L I + RGQ Y+NGSNM G+++GV
Sbjct:   91 CTVLGKRDNA-LSNCGFHKWKNLTYHLKEHEYSKGHCDNMRNWHELQRRLQNKTTIDQRQQTLMQIEIEHWKAVIRRVIAIICHLAERNQALRGTTSVLYDPHNGNFLAQVELMAKFDPVMNEHIRRRQNQEAKVHYLSGTIQNEIIAL----IGNKVLEEIITQRDYSVIMDCTPDISHKEQLSVVLRLVNC---------DPSVSIAEHFFGFIDVEDTSGKGLTEVLLDHLQKHNLSISDCRGQSYDNGSNMMGQKQGV 338          

HSP 2 Score: 131.339 bits (329), Expect = 2.957e-106
Identity = 80/222 (36.04%), Postives = 129/222 (58.11%), Query Frame = 3
Query:  969 ILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDECRRRRYKRQFEYEAQGTTRS 1634
            IL +N +A  IPC++H LNLV  DA+K  + +T+FF ++Q+++N FS+S QRW V   H+  LT+KPLS TRWE+RID  K  RYQL  I + L  +         +    + D++ ++ +     F++  + WYN+L +VN  SK+LQ  + ++ ++  + +  + YL   R +N       DA +IA+ L+ E      E ++R+ KRQF+YE    T+S
Sbjct:  342 ILQLNNKALCIPCSSHKLNLVVADAAKSSVLSTSFFGVLQRLYNLFSSSVQRWAVLRKHVKQLTLKPLSATRWEARIDSVKVVRYQLPEILEALSAL--------QTFGIEKGDSETMSSS-----FLLCTIIWYNVLYQVNHVSKLLQSPNVSMGTLRAETEGVREYLEDFR-ENRLASCQTDAKDIAENLDMEMNLP--EKKQRKKKRQFQYEGTEETQS 547          

HSP 3 Score: 76.2554 bits (186), Expect = 2.957e-106
Identity = 53/148 (35.81%), Postives = 82/148 (55.41%), Query Frame = 1
Query: 1633 PKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTD-CKHLETSLTHKENKDIDAYDLCN*LQV-VQRLPKPMS--PSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            P    + +F   + D A++S+ +R  +L+    L+ F++   N+ +      L + CK LE +L      DIDA DL   +   +   P  ++  P D+L YI  +K  D    +  +LR+LLTLPVSVASG+ SFS LKLIK+Y+R+
Sbjct:  549 PDETFRRDFFLPLVDTALRSLGDRLSRLKGVYDLYDFLFSKDNMKQTIKNGKLHERCKKLEQTL-----HDIDADDLAFEINSSLHTFPDHVATCPFDMLNYIYSEKLLDLYSTLSIALRLLLTLPVSVASGERSFSALKLIKTYMRS 691          

HSP 4 Score: 52.373 bits (124), Expect = 2.957e-106
Identity = 24/52 (46.15%), Postives = 34/52 (65.38%), Query Frame = 1
Query:   25 NIKLLHNFSNN-RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFCGFL 177
            +I+   N  N  RRF+  +Y+R + NGE++ RSWL+YS   D+VFCF C  L
Sbjct:   43 DIEFPQNSENPPRRFTKENYRRTMKNGEKILRSWLVYSMSTDSVFCFPCTVL 94          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000037907.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002089.1:152797:155023:-1 gene:ENSAMXG00000037599.1 transcript:ENSAMXT00000037907.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 196.438 bits (498), Expect = 6.811e-96
Identity = 104/283 (36.75%), Postives = 162/283 (57.24%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFF 1021
            C +F + S   L   G   W  I   L  HE++  H  N Q  +EL   +     ID+  Q+    E Q+W+ +L R++A++  LA +N A RG +EKL+  +NGNF   +E +A FDPV++ HL  +  ++I  HYL K IQN L+ ++ +  K+ I+  VK  KY+S+I+D TPD SH E M++++R V+     G+        I EHF+GF  +++T+G  +  TL ++LK M+L I + RGQ Y+NGSNM G ++GV K        ++F+ + C  F
Sbjct:   87 CTVFERESKFALSSSGFRSWINIHSHLRDHEKSKIHCANMQNLRELAERLKTGTAIDSACQELRALEVQHWKAVLRRILAIVCNLAERNQALRGHSEKLFEPHNGNFLGQIELMAQFDPVMSEHLRRIDKKEIKDHYLSKTIQNELISLVGQKTKDAIVQKVKDAKYFSVIMDCTPDTSHNEQMSLVLRIVNCESCSGAS-------ISEHFVGFFSVQDTSGRGLCNTLTKELKNMKLNIADCRGQSYDNGSNMMGHKQGVQKSAGDKPKGTVFFCVVCDLF 362          

HSP 2 Score: 105.531 bits (262), Expect = 6.811e-96
Identity = 65/189 (34.39%), Postives = 104/189 (55.03%), Query Frame = 3
Query: 1053 CLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDECRRRRYKRQFEYEAQ 1619
            C+    FF ++Q+++N FS+S  RW +   H V LTVK LS TRWE RI+  K  R+Q   + + L     +       G T  + A+ L   +  ++FI+ +V WYN+L  +N  SK+LQ  + AI++V ++    K +L + R D+G      +A EIA++L+ +  F     R+RR  R+F YE +
Sbjct:  356 CVVCDLFFGILQRLYNLFSSSVHRWSILQRH-VKLTVKNLSTTRWECRIESVKALRHQYPEMIEAL-SALTEHAAEKKDGETLYS-AQNLCKELMSWQFILCVVIWYNVLFHINHVSKLLQSPNMAIDAVKRETDHVKQFLQEYR-DHGISSAKTEAREIAEKLQVDMTFPV--ARQRRTTRKFLYEGK 538          

HSP 3 Score: 71.633 bits (174), Expect = 6.811e-96
Identity = 52/145 (35.86%), Postives = 75/145 (51.72%), Query Frame = 1
Query: 1633 PKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPMSPS-DVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            P+     EF   + D A+ SI ERF Q++    LFGF+Y  +N+ K     +   CK LE +L                       P+P S S D+L YI ++   +   N+  +L +LLTLP++VASG+ SFS LKLIK +LR+
Sbjct:  545 PEQHFNQEFFLPLIDTALISISERFTQVDVFFSLFGFLYSANNMKKAIQDTLEDSCKKLERTLGQ---------------------PRPGSGSEDILDYIYKENLLELYGNLSIALLLLLTLPITVASGERSFSSLKLIKHFLRS 668          

HSP 4 Score: 41.9726 bits (97), Expect = 6.811e-96
Identity = 17/37 (45.95%), Postives = 26/37 (70.27%), Query Frame = 1
Query:   58 RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            R+F+  +Y  K+ NGE++  +WL+YS   D+VFCF C
Sbjct:   51 RQFTVDNYHMKMNNGEKINWNWLVYSLSSDSVFCFCC 87          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000044961.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000032.1:419978:423709:1 gene:ENSAMXG00000036481.1 transcript:ENSAMXT00000044961.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 201.83 bits (512), Expect = 3.053e-82
Identity = 102/262 (38.93%), Postives = 164/262 (62.60%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGV 958
            C +F K  ++ L KL  ++WK +   L  HE +  H DN + W EL   +  + TID   Q  ++ E ++W+ ++ R+IA+I  LA +N A RGT  +LY+ +NGNF   VE +A FDPV+N H+  ++NQ+  VHYL   IQN ++ ++   +  +I+   +  KYYS+I+D TPD+SH E +++++R V+          +P+V I EHF GF+ +E+T+G  +TE L++ L++  L I + RGQ Y+NGSNM G+++GV
Sbjct:  141 CTVFGKRDNA-LSKLWFHKWKNLTYHLKEHEYSKGHCDNMRNWHELQRRLQNKTTIDQRQQALMQIEIEHWKAVIRRVIAIICHLAERNQALRGTTSELYDPHNGNFLAQVELMAKFDPVMNEHIRRIQNQEAKVHYLSGTIQNEIIALIGNKVLEEIVRRAQRAKYYSVIMDCTPDISHKEQLSVVLRLVNC---------DPSVSIAEHFFGFIDVEDTSGKGLTEVLLDHLQKHNLSISDCRGQSYDNGSNMMGQKQGV 392          

HSP 2 Score: 95.1301 bits (235), Expect = 3.053e-82
Identity = 42/81 (51.85%), Postives = 60/81 (74.07%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRID 1202
            Q  IL +N +A  IPC++H+LNLV  DA+K  + +T+FF ++Q+++N FS+S QRW V   H+  LT+KPLS TRWE+RID
Sbjct:  393 QARILQLNNKALCIPCSSHTLNLVVADAAKSSVLSTSFFGVLQRLYNLFSSSVQRWAVLRKHVKQLTLKPLSATRWEARID 473          

HSP 3 Score: 51.6026 bits (122), Expect = 3.053e-82
Identity = 23/49 (46.94%), Postives = 33/49 (67.35%), Query Frame = 1
Query:   25 NIKLLHNFSNN-RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            +I+   N  N  RRF+  +Y+R + NGE++ RSWL+YS   D+VFCF C
Sbjct:   93 DIQFPQNSENPPRRFTKENYRRTMKNGEKILRSWLVYSMSTDSVFCFPC 141          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000055782.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001476.1:1798:4262:-1 gene:ENSAMXG00000042376.1 transcript:ENSAMXT00000055782.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.91 bits (385), Expect = 6.015e-71
Identity = 87/235 (37.02%), Postives = 139/235 (59.15%), Query Frame = 2
Query:  266 ERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYN-NNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQ 967
            +++  H  N Q W+EL     + KT+            Q+ + +L R++A++  LA +N A RG +EKL+  +NGNF   +E +A    +++ HL  +  ++I  HYL K IQN L+ ++ +  K+ I+  VK  KY+S+I+D TPD SH E M++++R V+     G+        I EHF+GF  +++T+G  +  TL E+LK M+L I + RGQ YNNGSNM G ++GV K+
Sbjct:  159 KKSKIHRANMQNWREL---AERLKTV------------QHRKAVLRRILAIVCHLAERNQALRGHSEKLFEPHNGNFLGQIELMA---QLMSEHLRRIDKKEIKDHYLSKTIQNELISLVGQKTKDAIVQKVKDAKYFSVIMDCTPDTSHNEQMSLVLRIVNCESCSGAS-------ISEHFVGFFSVQDTSGRGLCNTLTEELKHMKLNIADCRGQSYNNGSNMMGHKQGVQKR 368          

HSP 2 Score: 110.923 bits (276), Expect = 6.015e-71
Identity = 60/155 (38.71%), Postives = 91/155 (58.71%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKED 1424
            Q  +L IN +A  +PC++HSLNLV  DA+K  + +  FF ++Q ++N FS+S  RW +   H V LTVK LS TRWE RI+  K  R+Q   + + L  +  +       G T  + A+ L   +  ++FI+ +V WYN+L  +N  SK+LQK +
Sbjct:  366 QKRVLEINQKALCVPCSSHSLNLVVADAAKSSVLSVTFFGILQWLYNLFSSSVHRWSILQRH-VKLTVKNLSTTRWECRIESVKALRHQYPEMIEAL-SVLTEHAAEKKDGETLYS-AQNLCKELMSWQFILCVVIWYNVLFHINHVSKLLQKPE 517          

HSP 3 Score: 47.3654 bits (111), Expect = 6.015e-71
Identity = 19/37 (51.35%), Postives = 27/37 (72.97%), Query Frame = 1
Query:   58 RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            RRF+  +Y  K+ NGE++ R+WL+YS   D+VFCF C
Sbjct:  111 RRFTVDNYHMKMNNGEKINRNWLVYSLSSDSVFCFCC 147          

HSP 4 Score: 92.0485 bits (227), Expect = 2.024e-18
Identity = 60/149 (40.27%), Postives = 89/149 (59.73%), Query Frame = 1
Query: 1633 PKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTD-CKHLETSLTHKENKDIDAYDLCN*LQV---VQRLPKPMS-PSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            P+ +   +    + D A+ SI ERF Q++    LFGF+Y  +N+ K    D L D CK LE +L      D+D+ DL   L+V   V   P  +S P+D+L YI ++   +   N+  +LR+LLTLP++VASG+ SFS LKLIK++LR+
Sbjct:  561 PEQRFNQDVFLPLIDTALISISERFTQVDVFFSLFGFLYYANNMKKAIQEDTLEDSCKKLERTLG-----DVDSQDLV--LEVTAAVSVFPDHISSPADILDYIYKENLLELYGNLSIALRLLLTLPITVASGERSFSSLKLIKNFLRS 702          
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000036272.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:11935414:11938921:1 gene:ENSAMXG00000041670.1 transcript:ENSAMXT00000036272.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 202.216 bits (513), Expect = 7.072e-56
Identity = 106/275 (38.55%), Postives = 162/275 (58.91%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLF 997
            CKLF   S+  L K G ++W  I + L SHE +  H      W+ELD  + K   ID      ++ E + W  +L+RL ++   LAT+NL FRG+++ LY  +NGNF K VE LA FD V   H+  +K+     HYLG+  QN ++ I+       I++ +K  KYY+IILD TPD+SH E M++++R V+++         P   IRE+FLG++ + ETTG  ++  ++EKL+ + +  E+ RGQ Y+NG+NMKGK +GV  +  +  P + F
Sbjct:  167 CKLFGTKSTR-LTKTGYSDWSNINICLRSHEGSPDHTKCMLQWRELDRRLRKNLAIDQQELSLMEAERKRWHDVLKRLFSITLSLATRNLPFRGSSQSLYVQDNGNFLKEVELLAQFDSVTEGHVARIKDDASRTHYLGQQTQNEIIEIICSQTIQTIVAKIKQAKYYAIILDCTPDISHKEQMSLVVRIVELV---------PEPHIREYFLGYMNVVETTGLNLSNVVLEKLRALGIPFEDCRGQAYDNGANMKGKRQGVQARLLQLNPRAAF 431          

HSP 2 Score: 37.3502 bits (85), Expect = 7.072e-56
Identity = 13/28 (46.43%), Postives = 19/28 (67.86%), Query Frame = 1
Query:   85 RKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            + L N E++ RSW++YS   + VFCF C
Sbjct:  140 KSLPNKEKIKRSWMVYSAQSNAVFCFPC 167          

HSP 3 Score: 126.716 bits (317), Expect = 1.036e-50
Identity = 70/219 (31.96%), Postives = 122/219 (55.71%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDECRRRRYKRQFEYEA 1616
            Q  +L +N +A F+PC AH++NLV  DA+K   +A ++F  +Q++  +FSA+TQRW +   H V LT+K  S+ RWESR+      R Q+  + + L++          +   +R++A+ LA+ +  F+F++  V W  +L+  +  +K+LQ     ++   + ++  K  L K R  +GF + +  A E+ + L  E + +  + R R  KRQF YEA
Sbjct:  419 QARLLQLNPRAAFVPCAAHTMNLVISDAAKSSTDAISYFGYLQRLFCFFSAATQRWDILLKH-VKLTLKSWSDVRWESRLQSVVAVRSQVKEVREALLEA-----RQAVTEPVARSEAQGLAEEVGSFRFLICTVVWAEVLSVTSQVNKVLQSSSMQLDIAARLIKTAKESLTKYRQ-SGFSEAIESAKELCEALNIEPELK--QKRLRSTKRQFGYEA 628          

HSP 4 Score: 95.1301 bits (235), Expect = 1.036e-50
Identity = 57/157 (36.31%), Postives = 92/157 (58.60%), Query Frame = 1
Query: 1618 KAPQDP----KHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPMSPS----DVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            +AP +P    + +++VEF   + D A+ S++ERF+ + Q    FG + D   ++  +  D+   C  +E  LT K   DID  ++   +Q +  LP+ +SP     ++L Y+     ++  PN+  +LRI LTLPV+VAS + SFSKLKLIK+YLR+
Sbjct:  627 EAPDEPFSDAQKRLEVEFFNHVVDSALTSLQERFETMSQVRDTFGVLLDFQKVHGISKQDLHNHCMDVEKKLTDKGEADIDGQEM---MQEIINLPQ-LSPQTTAFELLTYLHDNSLQEVYPNLWIALRIALTLPVTVASAERSFSKLKLIKTYLRS 779          
BLAST of TTF-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002687.1 (pep scaffold:Pmarinus_7.0:GL476762:168559:233001:1 gene:ENSPMAG00000002412.1 transcript:ENSPMAT00000002687.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.1662 bits (165), Expect = 5.282e-12
Identity = 31/85 (36.47%), Postives = 50/85 (58.82%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            N    + +   PMC+Y+   + +LKQ  +K  MNSVLENF++ Q V   +T+E LLC+ Y+F V+  + G     Q+ +Y +V +
Sbjct:  357 NGRFVYRIHRSPMCEYMINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQETLLCVAYVFEVSTSEHG----AQHHIYKLVKD 437          
BLAST of TTF-type domain-containing protein vs. Ensembl Nematostella
Match: EDO36811 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHJ8])

HSP 1 Score: 71.2478 bits (173), Expect = 7.777e-13
Identity = 33/85 (38.82%), Postives = 50/85 (58.82%), Query Frame = 1
Query: 3496 NNEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            N    + +   PMC+Y+   + +LKQ  +K  MNSVLENF++ Q V   ET+E LLCL Y+F V+  + G     Q+ +Y +V +
Sbjct:  293 NGRFVYRIHRSPMCEYMINFIHKLKQLPEKYMMNSVLENFTILQVVSNRETQETLLCLAYVFEVSTSEHG----AQHHIYRLVKD 373          
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000028133.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:111948955])

HSP 1 Score: 206.068 bits (523), Expect = 2.273e-59
Identity = 118/293 (40.27%), Postives = 176/293 (60.07%), Query Frame = 2
Query:  176 CKLF-NKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLC-IVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDII-KPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL*C 1042
            CKLF NKN +  L   G+  WK     L++HE++  HL+  +AWKEL   I   KTID      ++EE   WR +L RLIA+++ LA +NLA RG  E L+ ++NGNF K VE +A FDP++  HL  +++       Y+G  +QN L+ +L+  I + I+  +K  KY+SIILD T D+SH E +++IIR V ++ KP           IREHF+GF+  EE+TG  +   ++ +L+++ +  E+ RGQ Y+NG+NMKGK KGV  +  +  P +LF  L C    L+ + C
Sbjct:  198 CKLFSNKNIN--LTTSGTANWKHASTYLTAHEKSPEHLNCMKAWKELSGRIRSGKTIDKQEMALLEEERVRWRAVLTRLIAIVQSLAVRNLALRGHTETLFTSSNGNFLKEVELMARFDPIMKDHLNRVLRGTASHNSYIGHHVQNELIDLLSSKILSAIVDDIKKAKYFSIILDCTLDISHTEQLSVIIRVVSLMEKPQ----------IREHFMGFLEAEESTGQHLASMILNRLEELGISFEDCRGQSYDNGANMKGKNKGVQARLLEKNPRALF--LPCGAHTLNLVVC 476          

HSP 2 Score: 45.0542 bits (105), Expect = 2.273e-59
Identity = 16/42 (38.10%), Postives = 30/42 (71.43%), Query Frame = 1
Query:   43 NFSNNRRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            N S+ R     ++++ L +GE++ R+WL+YS +K+++FCF C
Sbjct:  157 NDSDGRSCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCC 198          

HSP 3 Score: 135.576 bits (340), Expect = 3.751e-49
Identity = 76/223 (34.08%), Postives = 129/223 (57.85%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFD---DPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDECRRRRYKRQFEYEAQ 1619
            Q  +L  N +A F+PC AH+LNLV  DA+K  ++A ++F ++Q+++  FSAS QRW +  S + I T+K  +ETRWES+I   +P RYQ   + + LI++ D   DP +        + +A++L++ +  ++F +  V W++IL+ +   SK++Q  +  ++     L+ T+  L   R+ NGF    + A E+ KE+  EA  +  + R R  K QF YE+ 
Sbjct:  451 QARLLEKNPRALFLPCGAHTLNLVVCDAAKRSVDAMSYFGVLQKLYTLFSASAQRWAILKSQVSI-TLKSWTETRWESKIKSIEPMRYQGAAVREALIEVRDKTKDPVI--------KAEAQSLSEEVGSYRFNICTVVWHDILSTIKHVSKLMQSPNMHVDLAVSLLKKTEQSLQSYRA-NGFVNAQMAAKEMCKEMNVEAILK--QKRIRSTKCQFSYESH 661          

HSP 4 Score: 81.2629 bits (199), Expect = 3.751e-49
Identity = 52/147 (35.37%), Postives = 84/147 (57.14%), Query Frame = 1
Query: 1630 DPKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPMSPS--DVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            D   K++VEF   + D A+ +I ERF  LE     FG + +  ++  +  T+    C+ L   L  ++N D+D+ +L   ++ +  LP   +PS  +++ ++  +   +  PN   +LRI LTLPV+VA  + SFSKLKLIKSYLR+
Sbjct:  667 DALKKLEVEFFNVVVDEALSAIAERFSTLEVVQNRFGVLTNFPSLGDEELTE---QCEALGNILHFEKNWDLDSRELVQEIKNLPNLPS-TTPSLLELISFMSDKDLSEIYPNFWTALRIALTLPVTVAQAERSFSKLKLIKSYLRS 809          
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000042294.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:110016639])

HSP 1 Score: 206.068 bits (523), Expect = 2.273e-59
Identity = 118/293 (40.27%), Postives = 176/293 (60.07%), Query Frame = 2
Query:  176 CKLF-NKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLC-IVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDII-KPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL*C 1042
            CKLF NKN +  L   G+  WK     L++HE++  HL+  +AWKEL   I   KTID      ++EE   WR +L RLIA+++ LA +NLA RG  E L+ ++NGNF K VE +A FDP++  HL  +++       Y+G  +QN L+ +L+  I + I+  +K  KY+SIILD T D+SH E +++IIR V ++ KP           IREHF+GF+  EE+TG  +   ++ +L+++ +  E+ RGQ Y+NG+NMKGK KGV  +  +  P +LF  L C    L+ + C
Sbjct:  198 CKLFSNKNIN--LTTSGTANWKHASTYLTAHEKSPEHLNCMKAWKELSGRIRSGKTIDKQEMALLEEERVRWRAVLTRLIAIVQSLAVRNLALRGHTETLFTSSNGNFLKEVELMARFDPIMKDHLNRVLRGTASHNSYIGHHVQNELIDLLSSKILSAIVDDIKKAKYFSIILDCTLDISHTEQLSVIIRVVSLMEKPQ----------IREHFMGFLEAEESTGQHLASMILNRLEELGISFEDCRGQSYDNGANMKGKNKGVQARLLEKNPRALF--LPCGAHTLNLVVC 476          

HSP 2 Score: 45.0542 bits (105), Expect = 2.273e-59
Identity = 16/42 (38.10%), Postives = 30/42 (71.43%), Query Frame = 1
Query:   43 NFSNNRRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            N S+ R     ++++ L +GE++ R+WL+YS +K+++FCF C
Sbjct:  157 NDSDGRSCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCC 198          

HSP 3 Score: 135.576 bits (340), Expect = 3.751e-49
Identity = 76/223 (34.08%), Postives = 129/223 (57.85%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFD---DPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDECRRRRYKRQFEYEAQ 1619
            Q  +L  N +A F+PC AH+LNLV  DA+K  ++A ++F ++Q+++  FSAS QRW +  S + I T+K  +ETRWES+I   +P RYQ   + + LI++ D   DP +        + +A++L++ +  ++F +  V W++IL+ +   SK++Q  +  ++     L+ T+  L   R+ NGF    + A E+ KE+  EA  +  + R R  K QF YE+ 
Sbjct:  451 QARLLEKNPRALFLPCGAHTLNLVVCDAAKRSVDAMSYFGVLQKLYTLFSASAQRWAILKSQVSI-TLKSWTETRWESKIKSIEPMRYQGAAVREALIEVRDKTKDPVI--------KAEAQSLSEEVGSYRFNICTVVWHDILSTIKHVSKLMQSPNMHVDLAVSLLKKTEQSLQSYRA-NGFVNAQMAAKEMCKEMNVEAILK--QKRIRSTKCQFSYESH 661          

HSP 4 Score: 81.2629 bits (199), Expect = 3.751e-49
Identity = 52/147 (35.37%), Postives = 84/147 (57.14%), Query Frame = 1
Query: 1630 DPKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPMSPS--DVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            D   K++VEF   + D A+ +I ERF  LE     FG + +  ++  +  T+    C+ L   L  ++N D+D+ +L   ++ +  LP   +PS  +++ ++  +   +  PN   +LRI LTLPV+VA  + SFSKLKLIKSYLR+
Sbjct:  667 DALKKLEVEFFNVVVDEALSAIAERFSTLEVVQNRFGVLTNFPSLGDEELTE---QCEALGNILHFEKNWDLDSRELVQEIKNLPNLPS-TTPSLLELISFMSDKDLSEIYPNFWTALRIALTLPVTVAQAERSFSKLKLIKSYLRS 809          
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000045044.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:111948193])

HSP 1 Score: 206.068 bits (523), Expect = 2.273e-59
Identity = 118/293 (40.27%), Postives = 176/293 (60.07%), Query Frame = 2
Query:  176 CKLF-NKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLC-IVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDII-KPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFFKLSFL*C 1042
            CKLF NKN +  L   G+  WK     L++HE++  HL+  +AWKEL   I   KTID      ++EE   WR +L RLIA+++ LA +NLA RG  E L+ ++NGNF K VE +A FDP++  HL  +++       Y+G  +QN L+ +L+  I + I+  +K  KY+SIILD T D+SH E +++IIR V ++ KP           IREHF+GF+  EE+TG  +   ++ +L+++ +  E+ RGQ Y+NG+NMKGK KGV  +  +  P +LF  L C    L+ + C
Sbjct:  198 CKLFSNKNIN--LTTSGTANWKHASTYLTAHEKSPEHLNCMKAWKELSGRIRSGKTIDKQEMALLEEERVRWRAVLTRLIAIVQSLAVRNLALRGHTETLFTSSNGNFLKEVELMARFDPIMKDHLNRVLRGTASHNSYIGHHVQNELIDLLSSKILSAIVDDIKKAKYFSIILDCTLDISHTEQLSVIIRVVSLMEKPQ----------IREHFMGFLEAEESTGQHLASMILNRLEELGISFEDCRGQSYDNGANMKGKNKGVQARLLEKNPRALF--LPCGAHTLNLVVC 476          

HSP 2 Score: 45.0542 bits (105), Expect = 2.273e-59
Identity = 16/42 (38.10%), Postives = 30/42 (71.43%), Query Frame = 1
Query:   43 NFSNNRRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            N S+ R     ++++ L +GE++ R+WL+YS +K+++FCF C
Sbjct:  157 NDSDGRSCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCC 198          

HSP 3 Score: 135.576 bits (340), Expect = 3.751e-49
Identity = 76/223 (34.08%), Postives = 129/223 (57.85%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFD---DPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDECRRRRYKRQFEYEAQ 1619
            Q  +L  N +A F+PC AH+LNLV  DA+K  ++A ++F ++Q+++  FSAS QRW +  S + I T+K  +ETRWES+I   +P RYQ   + + LI++ D   DP +        + +A++L++ +  ++F +  V W++IL+ +   SK++Q  +  ++     L+ T+  L   R+ NGF    + A E+ KE+  EA  +  + R R  K QF YE+ 
Sbjct:  451 QARLLEKNPRALFLPCGAHTLNLVVCDAAKRSVDAMSYFGVLQKLYTLFSASAQRWAILKSQVSI-TLKSWTETRWESKIKSIEPMRYQGAAVREALIEVRDKTKDPVI--------KAEAQSLSEEVGSYRFNICTVVWHDILSTIKHVSKLMQSPNMHVDLAVSLLKKTEQSLQSYRA-NGFVNAQMAAKEMCKEMNVEAILK--QKRIRSTKCQFSYESH 661          

HSP 4 Score: 81.2629 bits (199), Expect = 3.751e-49
Identity = 52/147 (35.37%), Postives = 84/147 (57.14%), Query Frame = 1
Query: 1630 DPKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPMSPS--DVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            D   K++VEF   + D A+ +I ERF  LE     FG + +  ++  +  T+    C+ L   L  ++N D+D+ +L   ++ +  LP   +PS  +++ ++  +   +  PN   +LRI LTLPV+VA  + SFSKLKLIKSYLR+
Sbjct:  667 DALKKLEVEFFNVVVDEALSAIAERFSTLEVVQNRFGVLTNFPSLGDEELTE---QCEALGNILHFEKNWDLDSRELVQEIKNLPNLPS-TTPSLLELISFMSDKDLSEIYPNFWTALRIALTLPVTVAQAERSFSKLKLIKSYLRS 809          
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000027735.1 (pep primary_assembly:ASM223467v1:9:30712608:30715295:1 gene:ENSORLG00000030268.1 transcript:ENSORLT00000027735.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.9745 bits (232), Expect = 1.748e-20
Identity = 71/253 (28.06%), Postives = 119/253 (47.04%), Query Frame = 2
Query:  254 LSSHERNTFHLDNFQAWKELDVSISK----EKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLYNNNGNFSKFVEYLALFDPVINVHLCIVKNQDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIEN-LRGQRYNNGSNMKGKEKGVPKQHSKHKPASLF 997
            L  H R+  H     AW E + S S       ++D    + +KE  +Y + + E L+    + ATQN+A RG  E   ++ GNF   +E LA  +P++   +   +N       LG   QN ++  LA  +++ I   V  ++ +SI++D T D+S  E M+ +IR+           +  +V   E FL F   +    A +++ +IE L++  L  +N L GQ Y+  S M GK  GV  +     P + +
Sbjct:  177 LLGHARSEAHTTAMLAWAEYEKSTSGTASLSASLDAEYSKLVKENREYIKVVGETLL----LTATQNIAQRGHKESEVDSKGNFLAIMELLAKNNPIVKRKMAGQRNATC----LGHDTQNEMIDCLAEMVRSSITGEVAESEAFSILVDETKDMSKKEQMSFVIRY----------YYNGSVC--ECFLAFEAAQRLNAAALSQKIIEILQKHGLDYKNHLVGQAYDGASVMSGKNTGVQARIKSEAPLAFY 409          

HSP 2 Score: 26.5646 bits (57), Expect = 1.748e-20
Identity = 9/16 (56.25%), Postives = 11/16 (68.75%), Query Frame = 1
Query:  121 WLIYSTIKDTVFCFFC 168
            WL YS  KD+ FC+ C
Sbjct:  130 WLEYSQSKDSAFCYAC 145          
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: tead3a (transcriptional enhancer factor TEF-5 [Source:NCBI gene;Acc:100049312])

HSP 1 Score: 70.8626 bits (172), Expect = 2.678e-12
Identity = 32/80 (40.00%), Postives = 49/80 (61.25%), Query Frame = 1
Query: 3511 FVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 3750
            F +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   ET+E LLC+ ++F V+  + G     QY +Y +VN+
Sbjct:  285 FRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVSNRETQETLLCIAFVFEVSTSEHG----AQYHVYRLVND 360          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000036749.1 (SMESG000036749.1)

HSP 1 Score: 155.221 bits (391), Expect = 1.909e-57
Identity = 87/219 (39.73%), Postives = 128/219 (58.45%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPD-ECRRRRYKRQFEYE 1613
            Q  IL+   +A F+PCNAH+LNL   DA+       +FFS V  I N+FSAS  RW V   ++  LT+K +SETRWE+RI   +P R +LG IYD+LI+I ++     SS  T + +A+ LA  +  +KFI S++ W+ IL +V+  SK++QK    I+S  + ++    Y    R+D  FE  L  + E+   LETE  F  +   R R +++QF YE
Sbjct:  364 QKRILDNYPRALFMPCNAHTLNLAINDAANVSFSTVDFFSNVSAISNFFSASPFRWQVLKKNVKSLTLKQVSETRWEARIKAIRPLRNELGEIYDSLIEIAEE-----SSMPTVQHEAECLAMKLKSYKFISSIIIWFEILEKVDFISKMMQKVSWNISSCAESIKEVLKYFKSIRNDESFENYLQISNELCVALETEPDFPAEISVRSRHHRKQFSYE 577          

HSP 2 Score: 88.9669 bits (219), Expect = 1.909e-57
Identity = 53/145 (36.55%), Postives = 81/145 (55.86%), Query Frame = 1
Query: 1633 PKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPM-SPSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            PK   ++ F Y I D AI S+  RF+ L   +  FGF+Y   ++  +   +I   C  L       E+ DI   +L   L  ++ + K    P +++ ++ +   E   PNV  SL++LLT+PVSVASG+ SFSKLK+IK++LRT
Sbjct:  586 PKEHFQISFSYVILDTAISSLTTRFETLSGFERCFGFLYKFIDMEHE---EIKKSCFDLHNKFKDGESCDISGVELYQELVSLKIIIKDRKQPEELIKFLYKYNLETSFPNVATSLKLLLTVPVSVASGERSFSKLKIIKNHLRT 727          

HSP 3 Score: 170.244 bits (430), Expect = 7.841e-43
Identity = 94/228 (41.23%), Postives = 146/228 (64.04%), Query Frame = 2
Query:  329 KEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLCIVKN----QDIMVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLF 997
            ++ TID   Q+    E++ W QI++R+I++++ LA Q LAFRG++ KLY  NNGNF K +E +  FD ++  H+  V+     ++ M HYLG   QN ++ ILA  I+  IL+ +K  KY+S+ILD TPD  H+E +T++IR+V I      + +E  V +RE+F+GF   ++ TG    + LI+KL  +EL I ++RGQ Y+NGSNM GK +G+ K+   + P +LF
Sbjct:  157 RKTTIDKNMQRYYDAEKKRWCQIIKRMISMVQFLAGQCLAFRGSSGKLYEKNNGNFLKAIEMIGKFDDIMADHIKRVQEPNAPKNRMPHYLGNRFQNEIIAILATQIQKYILTSIKEAKYFSVILDCTPDTGHVEQITMVIRYVHI------KNYE--VEVRENFIGFYQAKKCTGESFYDFLIQKLNYIELNISDMRGQGYDNGSNMSGKHRGLQKRILDNYPRALF 376          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000047334.1 (SMESG000047334.1)

HSP 1 Score: 154.066 bits (388), Expect = 6.348e-57
Identity = 89/220 (40.45%), Postives = 129/220 (58.64%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPDE--CRRRRYKRQFEYE 1613
            Q  IL+   +A F+PCNAH+LNL   DA+       +FFS V  I+N FSAS  RW V   ++  LT+K +SET+WE+RI   +P R +LG IYD+LI+I ++     SS  T R +A+ LA  +  +KFI S++ WY IL +V+  SK++QK    I+S  + ++    +    R+D  FE  L  + E+   LETE  F P E   R R +++QF YE
Sbjct:  539 QKRILDNYPRALFMPCNAHTLNLAINDAANVSFSTVDFFSNVSAIYNIFSASPFRWQVLKKNVKSLTLKQVSETQWEARIKAIRPLRNELGEIYDSLIEIAEE-----SSMPTVRHEAECLAMKLKSYKFISSIIIWYEILEKVDFISKMMQKVSWNISSCAESIKEVLKFFKSIRNDESFENYLQISNELCVALETEPDF-PAEIIVRSRHHRKQFSYE 752          

HSP 2 Score: 88.5817 bits (218), Expect = 6.348e-57
Identity = 53/145 (36.55%), Postives = 81/145 (55.86%), Query Frame = 1
Query: 1633 PKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPM-SPSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            PK   ++ F Y I D AI S+  RF+ L   +  FGF+Y   ++  +   +I   C  L       E+ DI   +L   L  ++ + K    P +++ ++ +   E   PNV  SL++LLT+PVSVASG+ SFSKLK+IK++LRT
Sbjct:  761 PKEHFQISFFYVILDTAISSLTTRFETLSGFERCFGFLYKFIDMEHE---EIKKSCFDLHNKFKDGESCDISGVELYQELVSLKIIIKDRKQPEELIKFLYKYNLETSFPNVATSLKLLLTVPVSVASGERSFSKLKIIKNHLRT 902          

HSP 3 Score: 171.785 bits (434), Expect = 1.526e-48
Identity = 99/279 (35.48%), Postives = 157/279 (56.27%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLCIVKNQDI----MVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLF 997
            CKLF K    ++ + G N+W+ I   LS HE+ T H++N+  WK+L++++ ++ TID   Q+    E++ W QI++R+I++++ LA Q LAFRG++  LY  NNGNF K +E +  FD ++  H+  V+  +     M HYLG   QN ++ ILA  I+  IL+ +K  KY+S+ILD TPD  H+E +T++IR+V I                                  +    +L  +EL I ++RGQ Y+NGSNM GK + + K+   + P +LF
Sbjct:  308 CKLFGKQEIKLVNE-GFNDWQHISDNLSRHEKTTLHIENYTCWKKLELNLKRKTTIDKNMQRYYDAEKKRWCQIVKRMISVVQFLAGQCLAFRGSSGILYEKNNGNFLKAIEMIGKFDDIMADHIKRVQEPNAPKNRMPHYLGNRFQNEIIAILATQIQKYILTSIKEAKYFSVILDCTPDTGHVEQITMVIRYVHI----------------------------------KNYEVELNYLELNISDMRGQGYDNGSNMSGKHRRLQKRILDNYPRALF 551          

HSP 4 Score: 42.3578 bits (98), Expect = 1.526e-48
Identity = 19/37 (51.35%), Postives = 24/37 (64.86%), Query Frame = 1
Query:   58 RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            R FS +++ RKL NGE+  R  LIYS   D +FCF C
Sbjct:  272 RSFSKVYFYRKLPNGEKFNRELLIYSPKNDAIFCFCC 308          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1)

HSP 1 Score: 158.688 bits (400), Expect = 1.937e-56
Identity = 87/219 (39.73%), Postives = 130/219 (59.36%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPD-ECRRRRYKRQFEYE 1613
            Q  IL+   +A F+PCNAH+LNL   DA+       +FFS V  ++N+FSAS  RW V   ++  LT+K +SETRWE+RI   +P R +LG IYD+LI+I ++     SS  T R +A+ LA+ +  +KFI S++ WY IL +V+  SK++QK    I+S  + ++    +    R+D  FE  L  + E+   LETE  F  +   R R +++QF YE
Sbjct:  391 QKRILDNYPRALFMPCNAHTLNLAINDAANVSFSTVDFFSNVSAVYNFFSASPFRWQVLKKNVKSLTLKQVSETRWEARIKAIRPLRNELGEIYDSLIEIAEE-----SSMPTVRHEAECLANKLKSYKFISSIIIWYEILEKVDFISKMMQKVSWNISSCAESIKEVLKFFKSIRNDESFENYLQISNELCVALETEPDFPAEISVRSRHHRKQFSYE 604          

HSP 2 Score: 82.0333 bits (201), Expect = 1.937e-56
Identity = 51/145 (35.17%), Postives = 79/145 (54.48%), Query Frame = 1
Query: 1633 PKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPM-SPSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            PK   ++ F   I D AI S+  RF+ L   +  FGF+Y   ++  +   +I   C  L       E+ DI   +L   L  ++ + K    P +++ ++ +   E   PNV  SL++LLT+PV VASG+ SFSKLK+IK++LRT
Sbjct:  613 PKEHFQISFFNVILDTAISSLTTRFETLSGFERCFGFLYKFIDMEHE---EIKKSCFDLHNKFKDGESCDISGVELYQELVSLKIIIKDRKQPEELIKFLYKYNLETSFPNVATSLKLLLTVPVFVASGERSFSKLKIIKNHLRT 754          

HSP 3 Score: 146.747 bits (369), Expect = 6.364e-42
Identity = 93/279 (33.33%), Postives = 144/279 (51.61%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLCIVKNQDI----MVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLF 997
            CKLF K    ++ + G N+W+ I   LS HE+ T H++N   WK+L +++ ++ TID   Q+    E++ W QI++R+I++++ LA Q LAFRG++ KLY  NNGNF K +E +  FD  +  H+  V+  +     M HY G   QN ++ ILA  I+  IL+ +K  KY+S+ILD TPD  H+E +T++I                                                      ++RGQ Y+NGSNM GK +G+ K+   + P +LF
Sbjct:  179 CKLFGKQEIKLVNE-GFNDWQHISDNLSRHEKTTLHIENCTCWKKLKLNLKRKTTIDKNMQRYYDAEKKRWCQIVKRMISVVQFLAGQCLAFRGSSGKLYEKNNGNFLKAIEMIGKFDDTMADHIKRVQEPNAPKNHMPHYQGNRFQNEIIAILATQIQKYILTSIKEAKYFSVILDCTPDTGHVEQITMVI-----------------------------------------------------SDMRGQGYDNGSNMSGKHRGLQKRILDNYPRALF 403          

HSP 4 Score: 45.4394 bits (106), Expect = 6.364e-42
Identity = 20/37 (54.05%), Postives = 24/37 (64.86%), Query Frame = 1
Query:   58 RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            R FS +++ RKL NGE+  R WLIYS   D  FCF C
Sbjct:  143 RSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCC 179          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1)

HSP 1 Score: 158.688 bits (400), Expect = 2.036e-56
Identity = 87/219 (39.73%), Postives = 130/219 (59.36%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPD-ECRRRRYKRQFEYE 1613
            Q  IL+   +A F+PCNAH+LNL   DA+       +FFS V  ++N+FSAS  RW V   ++  LT+K +SETRWE+RI   +P R +LG IYD+LI+I ++     SS  T R +A+ LA+ +  +KFI S++ WY IL +V+  SK++QK    I+S  + ++    +    R+D  FE  L  + E+   LETE  F  +   R R +++QF YE
Sbjct:  410 QKRILDNYPRALFMPCNAHTLNLAINDAANVSFSTVDFFSNVSAVYNFFSASPFRWQVLKKNVKSLTLKQVSETRWEARIKAIRPLRNELGEIYDSLIEIAEE-----SSMPTVRHEAECLANKLKSYKFISSIIIWYEILEKVDFISKMMQKVSWNISSCAESIKEVLKFFKSIRNDESFENYLQISNELCVALETEPDFPAEISVRSRHHRKQFSYE 623          

HSP 2 Score: 82.0333 bits (201), Expect = 2.036e-56
Identity = 51/145 (35.17%), Postives = 79/145 (54.48%), Query Frame = 1
Query: 1633 PKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPM-SPSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            PK   ++ F   I D AI S+  RF+ L   +  FGF+Y   ++  +   +I   C  L       E+ DI   +L   L  ++ + K    P +++ ++ +   E   PNV  SL++LLT+PV VASG+ SFSKLK+IK++LRT
Sbjct:  632 PKEHFQISFFNVILDTAISSLTTRFETLSGFERCFGFLYKFIDMEHE---EIKKSCFDLHNKFKDGESCDISGVELYQELVSLKIIIKDRKQPEELIKFLYKYNLETSFPNVATSLKLLLTVPVFVASGERSFSKLKIIKNHLRT 773          

HSP 3 Score: 164.081 bits (414), Expect = 3.805e-47
Identity = 101/279 (36.20%), Postives = 156/279 (55.91%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLCIVKNQDI----MVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLF 997
            CKLF K    ++ + G N+W+ I   LS HE+ T H++N   WK+L +++ ++ TID   Q+    E++ W QI++R+I++++ LA Q LAFRG++ KLY  NNGNF K +E +  FD  +  H+  V+  +     M HY G   QN ++ ILA  I+  IL+ +K  KY+S+ILD TPD  H+E +T++IR+V                                 +I    +E L  +EL I ++RGQ Y+NGSNM GK +G+ K+   + P +LF
Sbjct:  179 CKLFGKQEIKLVNE-GFNDWQHISDNLSRHEKTTLHIENCTCWKKLKLNLKRKTTIDKNMQRYYDAEKKRWCQIVKRMISVVQFLAGQCLAFRGSSGKLYEKNNGNFLKAIEMIGKFDDTMADHIKRVQEPNAPKNHMPHYQGNRFQNEIIAILATQIQKYILTSIKEAKYFSVILDCTPDTGHVEQITMVIRYV---------------------------------YIKNYEVE-LNYLELNISDMRGQGYDNGSNMSGKHRGLQKRILDNYPRALF 422          

HSP 4 Score: 45.4394 bits (106), Expect = 3.805e-47
Identity = 20/37 (54.05%), Postives = 24/37 (64.86%), Query Frame = 1
Query:   58 RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            R FS +++ RKL NGE+  R WLIYS   D  FCF C
Sbjct:  143 RSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCC 179          
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1)

HSP 1 Score: 158.688 bits (400), Expect = 2.104e-56
Identity = 87/219 (39.73%), Postives = 130/219 (59.36%), Query Frame = 3
Query:  960 QNSILNINLQAFFIPCNAHSLNLVFYDASKCCLEATNFFSLVQQIHNYFSASTQRWHVFTSHIVILTVKPLSETRWESRIDVSKPKRYQLGPIYDTLIDIFDDPRLNNSSGNTSRTDAKALADAICKFKFIVSLVTWYNILNEVNVTSKILQKEDSAINSVTKQLQVTKNYLLKCRSDNGFEQVLIDAAEIAKELETEAKFEPD-ECRRRRYKRQFEYE 1613
            Q  IL+   +A F+PCNAH+LNL   DA+       +FFS V  ++N+FSAS  RW V   ++  LT+K +SETRWE+RI   +P R +LG IYD+LI+I ++     SS  T R +A+ LA+ +  +KFI S++ WY IL +V+  SK++QK    I+S  + ++    +    R+D  FE  L  + E+   LETE  F  +   R R +++QF YE
Sbjct:  410 QKRILDNYPRALFMPCNAHTLNLAINDAANVSFSTVDFFSNVSAVYNFFSASPFRWQVLKKNVKSLTLKQVSETRWEARIKAIRPLRNELGEIYDSLIEIAEE-----SSMPTVRHEAECLANKLKSYKFISSIIIWYEILEKVDFISKMMQKVSWNISSCAESIKEVLKFFKSIRNDESFENYLQISNELCVALETEPDFPAEISVRSRHHRKQFSYE 623          

HSP 2 Score: 82.0333 bits (201), Expect = 2.104e-56
Identity = 51/145 (35.17%), Postives = 79/145 (54.48%), Query Frame = 1
Query: 1633 PKHKIKVEFCYTI*DMAIQSIEERFQQLEQHDILFGFIYDISNINKKTSTDILTDCKHLETSLTHKENKDIDAYDLCN*LQVVQRLPKPM-SPSDVLLYIVQQKWEDCVPNVVASLRILLTLPVSVASGKHSFSKLKLIKSYLRT 2064
            PK   ++ F   I D AI S+  RF+ L   +  FGF+Y   ++  +   +I   C  L       E+ DI   +L   L  ++ + K    P +++ ++ +   E   PNV  SL++LLT+PV VASG+ SFSKLK+IK++LRT
Sbjct:  632 PKEHFQISFFNVILDTAISSLTTRFETLSGFERCFGFLYKFIDMEHE---EIKKSCFDLHNKFKDGESCDISGVELYQELVSLKIIIKDRKQPEELIKFLYKYNLETSFPNVATSLKLLLTVPVFVASGERSFSKLKIIKNHLRT 773          

HSP 3 Score: 164.466 bits (415), Expect = 2.992e-47
Identity = 101/279 (36.20%), Postives = 156/279 (55.91%), Query Frame = 2
Query:  176 CKLFNKNSSSILEKLGSNEWKIIGVILSSHERNTFHLDNFQAWKELDVSISKEKTIDNINQQNIKEEEQYWRQILERLIALIRVLATQNLAFRGTNEKLY-NNNGNFSKFVEYLALFDPVINVHLCIVKNQDI----MVHYLGKGIQNGLM*ILARAIKNKILSLVKSTKYYSIILDSTPDVSHIEHMTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEKLKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLF 997
            CKLF K    ++ + G N+W+ I   LS HE+ T H++N   WK+L +++ ++ TID   Q+    E++ W QI++R+I++++ LA Q LAFRG++ KLY  NNGNF K +E +  FD  +  H+  V+  +     M HY G   QN ++ ILA  I+  IL+ +K  KY+S+ILD TPD  H+E +T++IR+V                                 +I    +E L  +EL I ++RGQ Y+NGSNM GK +G+ K+   + P +LF
Sbjct:  179 CKLFGKQEIKLVNE-GFNDWQHISDNLSRHEKTTLHIENCTCWKKLKLNLKRKTTIDKNMQRYYDAEKKRWCQIVKRMISVVQFLAGQCLAFRGSSGKLYEKNNGNFLKAIEMIGKFDDTMADHIKRVQEPNAPKNHMPHYQGNRFQNEIIAILATQIQKYILTSIKEAKYFSVILDCTPDTGHVEQITMVIRYV---------------------------------YIKNYEVE-LNYLELNISDMRGQGYDNGSNMSGKHRGLQKRILDNYPRALF 422          

HSP 4 Score: 45.4394 bits (106), Expect = 2.992e-47
Identity = 20/37 (54.05%), Postives = 24/37 (64.86%), Query Frame = 1
Query:   58 RRFSPIHYKRKLANGEEVYRSWLIYSTIKDTVFCFFC 168
            R FS +++ RKL NGE+  R WLIYS   D  FCF C
Sbjct:  143 RSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCC 179          
The following BLAST results are available for this feature:
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ZMYM16.226e-1725.72zinc finger MYM-type containing 1 [Source:HGNC Sym... [more]
ZMYM16.226e-1725.72zinc finger MYM-type containing 1 [Source:HGNC Sym... [more]
ZMYM16.226e-1725.72zinc finger MYM-type containing 1 [Source:HGNC Sym... [more]
ZMYM16.226e-1725.72zinc finger MYM-type containing 1 [Source:HGNC Sym... [more]
ZMYM56.770e-1259.46zinc finger MYM-type containing 5 [Source:HGNC Sym... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egl-441.215e-1043.94Transcription enhancer factor-like protein egl-44 ... [more]
egl-441.222e-1043.94Transcription enhancer factor-like protein egl-44 ... [more]
egl-441.274e-1043.94Transcription enhancer factor-like protein egl-44 ... [more]
egl-441.296e-1043.94Transcription enhancer factor-like protein egl-44 ... [more]
egl-441.394e-1043.94Transcription enhancer factor-like protein egl-44 ... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sd5.186e-1341.77gene:FBgn0003345 transcript:FBtr0074100[more]
sd5.186e-1341.77gene:FBgn0003345 transcript:FBtr0308132[more]
sd5.186e-1341.77gene:FBgn0003345 transcript:FBtr0074101[more]
sd5.186e-1341.77gene:FBgn0003345 transcript:FBtr0308130[more]
sd5.291e-1341.77gene:FBgn0003345 transcript:FBtr0340115[more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CR762475.11.045e-2430.03pep chromosome:GRCz11:4:55494751:55498830:1 gene:E... [more]
tead3a3.928e-1137.50TEA domain family member 3 a [Source:ZFIN;Acc:ZDB-... [more]
tead3a3.970e-1137.50TEA domain family member 3 a [Source:ZFIN;Acc:ZDB-... [more]
tead3b9.029e-1136.25TEA domain family member 3 b [Source:ZFIN;Acc:ZDB-... [more]
tead1a6.134e-934.12TEA domain family member 1a [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000043220.11.171e-2930.66pep primary_assembly:Xenopus_tropicalis_v9.1:7:364... [more]
tbx184.770e-1327.11T-box 18 [Source:Xenbase;Acc:XB-GENE-489907][more]
slc10a62.426e-1226.15solute carrier family 10 (sodium/bile acid cotrans... [more]
pik3ca1.162e-1141.77phosphatidylinositol-4,5-bisphosphate 3-kinase cat... [more]
pik3ca1.210e-1141.77phosphatidylinositol-4,5-bisphosphate 3-kinase cat... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tead27.511e-1341.89TEA domain family member 2 [Source:MGI Symbol;Acc:... [more]
Tead22.537e-1141.89TEA domain family member 2 [Source:MGI Symbol;Acc:... [more]
Tead22.796e-1141.89TEA domain family member 2 [Source:MGI Symbol;Acc:... [more]
Tead22.796e-1141.89TEA domain family member 2 [Source:MGI Symbol;Acc:... [more]
Zmym11.838e-1020.50zinc finger, MYM domain containing 1 [Source:MGI S... [more]
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BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5SVZ6|ZMYM1_HUMAN2.990e-1625.72Zinc finger MYM-type protein 1 OS=Homo sapiens OX=... [more]
sp|P30052|SCAL_DROME8.662e-1241.77Protein scalloped OS=Drosophila melanogaster OX=72... [more]
sp|Q25214|SCAL_JUNCO1.337e-1133.67Protein scalloped (Fragment) OS=Junonia coenia OX=... [more]
sp|Q9UJ78|ZMYM5_HUMAN2.999e-1159.46Zinc finger MYM-type protein 5 OS=Homo sapiens OX=... [more]
sp|Q4R3D6|ZMYM5_MACFA5.661e-1159.46Zinc finger MYM-type protein 5 OS=Macaca fascicula... [more]
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BLAST of TTF-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
R4G9H64.911e-13540.00TTF-type domain-containing protein OS=Anolis carol... [more]
H9GS442.112e-11839.37TTF-type domain-containing protein OS=Anolis carol... [more]
G1KXP12.206e-11840.53Uncharacterized protein OS=Anolis carolinensis OX=... [more]
H3A8563.068e-11245.08TTF-type domain-containing protein OS=Latimeria ch... [more]
A0A5N4B4G42.453e-11042.11Uncharacterized protein OS=Photinus pyralis OX=705... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000025204.22.957e-10638.55pep primary_assembly:Astyanax_mexicanus-2.0:12:736... [more]
ENSAMXT00000037907.16.811e-9636.75pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000044961.13.053e-8238.93pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000055782.16.015e-7137.02pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000036272.17.072e-5638.55pep primary_assembly:Astyanax_mexicanus-2.0:20:119... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000002687.15.282e-1236.47pep scaffold:Pmarinus_7.0:GL476762:168559:233001:1... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO368117.777e-1338.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000028133.12.273e-5940.27zinc finger MYM-type protein 1-like [Source:NCBI g... [more]
ENSORLT00000042294.12.273e-5940.27zinc finger MYM-type protein 1-like [Source:NCBI g... [more]
ENSORLT00000045044.12.273e-5940.27zinc finger MYM-type protein 1-like [Source:NCBI g... [more]
ENSORLT00000027735.11.748e-2028.06pep primary_assembly:ASM223467v1:9:30712608:307152... [more]
tead3a2.678e-1240.00transcriptional enhancer factor TEF-5 [Source:NCBI... [more]
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BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000036749.11.909e-5739.73SMESG000036749.1[more]
SMESG000047334.16.348e-5740.45SMESG000047334.1[more]
SMESG000061124.11.937e-5639.73SMESG000061124.1[more]
SMESG000061124.12.036e-5639.73SMESG000061124.1[more]
SMESG000061124.12.104e-5639.73SMESG000061124.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006431 ID=SMED30006431|Name=TTF-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3813bp
CTGGCCTGACTATTGTAATGATAAAACATCAAATTATTACATAATTTTTC
CAACAATCGGAGATTTTCTCCAATTCACTATAAGAGAAAACTAGCCAATG
GTGAAGAAGTATACCGTTCATGGTTGATATATTCAACTATAAAAGATACA
GTTTTTTGTTTTTTTTGCGGTTTTTTGCAAGTTATTTAACAAAAACAGCT
CGTCAATCCTAGAAAAATTAGGATCAAATGAGTGGAAAATTATTGGAGTA
ATTCTATCTTCACATGAAAGGAATACTTTTCATTTAGACAACTTTCAGGC
GTGGAAAGAACTTGATGTGAGTATATCCAAAGAAAAAACAATTGATAATA
TTAACCAGCAGAATATCAAAGAAGAAGAACAATATTGGCGGCAAATTTTG
GAACGTTTGATCGCTTTGATTAGAGTACTTGCCACTCAAAACTTAGCATT
TCGTGGAACAAATGAAAAGTTGTACAATAACAACGGTAATTTTTCGAAGT
TTGTAGAATATCTAGCCCTCTTTGACCCTGTAATAAACGTACATTTGTGC
ATAGTCAAAAATCAAGACATTATGGTACATTATCTGGGAAAAGGTATTCA
AAATGGACTTATGTAGATCCTAGCAAGAGCTATTAAAAATAAAATTTTGT
CACTTGTGAAATCAACAAAATATTACTCAATTATTTTGGATTCCACACCA
GACGTTAGTCATATTGAACATATGACTATTATTATACGTTTTGTTGATAT
TATCAAACCCTTAGGTAGTGAGATATTCGAGCCTGCAGTAATAATAAGAG
AACATTTCCTAGGATTTGTTCCATTAGAAGAAACTACTGGGGCATTCATA
ACAGAAACTTTGATTGAAAAGCTTAAGCAAATGGAATTACAAATTGAAAA
TCTCCGTGGGCAAAGGTATAATAATGGAAGTAATATGAAAGGAAAAGAAA
AAGGTGTACCAAAACAGCATTCTAAACATAAACCTGCAAGCCTTTTTTAT
TCCCTGCAATGCACATTCTTTAAACTTAGTTTTCTATGATGCCTCTAAAT
GTTGCCTAGAAGCGACTAATTTCTTCAGTTTAGTTCAACAGATTCATAAT
TACTTCTCTGCATCGACTCAACGTTGGCATGTGTTTACTAGCCATATCGT
GATTTTAACAGTTAAACCATTGAGCGAAACAAGATGGGAAAGTAGGATTG
ATGTTTCGAAGCCTAAAAGGTATCAGCTTGGTCCAATATATGATACTTTA
ATAGATATTTTTGATGACCCAAGACTAAATAATTCATCTGGTAATACTTC
CCGAACTGACGCAAAGGCTCTTGCTGATGCAATTTGTAAATTCAAGTTTA
TTGTATCCCTTGTCACATGGTACAACATTCTTAATGAAGTGAATGTTACA
AGCAAAATACTACAAAAAGAGGATTCTGCTATAAATTCAGTTACAAAACA
ACTTCAAGTGACTAAGAATTACCTCTTAAAATGTAGGAGTGATAATGGTT
TTGAACAAGTTTTAATTGATGCTGCCGAGATCGCAAAGGAATTAGAAACA
GAAGCGAAATTTGAGCCCGATGAATGTAGAAGAAGGAGATATAAACGGCA
GTTTGAATATGAAGCTCAAGGCACCACAAGATCCTAAACATAAAATCAAA
GTAGAATTCTGCTACACTATCTAGGACATGGCTATACAGTCTATTGAAGA
GAGGTTCCAACAGTTAGAACAACATGATATTTTATTTGGCTTCATTTATG
ATATATCCAATATCAACAAAAAGACATCTACGGATATACTTACTGACTGC
AAACATTTAGAAACATCTTTGACGCATAAAGAAAATAAAGATATTGATGC
CTATGATCTTTGTAATTAGCTTCAAGTAGTTCAAAGGCTTCCAAAGCCTA
TGTCACCATCAGATGTACTCCTCTATATAGTACAACAAAAATGGGAAGAT
TGTGTACCAAATGTTGTTGCTTCCTTGAGAATATTATTAACACTTCCAGT
ATCCGTGGCTAGTGGAAAACACAGTTTTTCAAAATTGAAATTAATTAAAA
GTTACTTGCGTACCTGTGGACTTAGCAACAATTTCAATAGAATGTAATTA
CGCTTCGAAATTGGAATTGAAGGAATTAGTAGAAACTTTTGCGAGGAAGA
AGGCAAGAAAAATTAAATTTTAATTTTGTAACATTTATGCAATTGATAAT
AAATTAATGTCACTTTAATTTTATTGTTTTCTTATATATATTTATTTTTT
TATTAATTTGTGTGAAAGGGGGCGTTTTAATAAGTTTTGCCTAGGGCGAT
AAATAAGCTTTCGCCGGCCCTGGTGCCTTCACCCAGCCCCTCCCCCCACC
TTGTCAATATAACATTAGGAGGTACCCCTATCGATTCTTTAGATCTTGTT
TGTTTTTAATGGTGCTGCCTTTAACGATAAAAATTAATATCTTCAAACTG
CAAAAGTAATTTTGGTGTAATTAATAATATTTGATTTTCAAAATATTCTA
AAACATTGACTTTTGGGTTGGCCTACTTATTATTCATTTTAATTTCAAAG
AAATTATATTTTCCAAATGTATTTATTTCTAAAGAGCATCATTTGATGAT
ATTGTTAGTGAATTACCTGAAATACGGATACAGCGTAAGGGTAATGAAAC
AAAATATACTTGCATAAATTTTTCAAAAGAAACAAGAAATTTTTATCATT
AACAGCTGAAATAAGAAATCACGAAGGATAGCAAGTGGCCTATTTTGGCG
CCCGACCTCGCCACCTCCCTCAAAGGCCGGCACTGGGAGAGCCCAGTTTA
ATATTATATGATTAAGCCACATTGATTATTTTAATGTAAGTGAAGAATAC
AATTTTATTATTTAACATTATTCAGTAAATAATTTAATTTTTCTCGTTCT
TGAAATTTTTTTGGTTGGTGTTGAAACTATTCTCGATAAAAATAATCTTG
ATGAAATTTTGAGAAATTCAAATAGTGATATAAATTGGTTAAATTTCAAT
CAAAATCTTTTACAATTCACAGATGAATTCTAAAACACTCCGAAAACGAT
ATGACAATTTCAGTGAACAAATACATTTGAAATTTCATTAGAAAATAATG
TTGGAAACATTTTTTTTCAACTAAATTCTTTAATCTGATTGGCCTATTTA
ATGTGACTTACGTAATTGACTACAAGGTTGAAATTATTTATTTTGTTGAG
CTCATTATTCATTAATTACTTTAGAGAAAATTTTTCTTTTATTACAGAAA
TTTCTTTTACTAATAATTTTACTGACACAATTTTTTTATAATAAATAATT
TTCAGTTTTATTGAACGTTATAATTACAGAATCACAGTAGCTAAAATCTC
ATTGTTCATTGAAATATTAAAAAATAATTATCTTGCTTTTATCATTTTTC
TATTAACGGTGACTAGTGTGATATGTGAAAGTATAAAGTTTGAGAAAAAT
TTGAAATTTAAAAGTATTATATAGATTATTGACCATTCCACTGCCAATAA
CGAAATGGGTTTCGTCGTTGAGAATTATCCCATGTGTGATTATCTCAAAA
AACTGCTGGTTCGATTAAAACAGTTCAAAGACAAAGAAACCATGAATTCA
GTTTTAGAAAACTTCAGTGTTTTTCAAACTGTGCAAAAGGCTGAAACTGA
AGAAATTCTTCTTTGTTTAACATATTTATTTTCTGTTGCTGAACGAGATA
GTGGAAACGGGGGCCATTGTCAATATAGACTTTATAGTATTGTTAACAAT
TAATTGTTATCATTCTATTTGTAATAATAATTGTAATATTTTGTAATAGA
CTTTTCAAAAGCG
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protein sequence of SMED30006431-orf-1

>SMED30006431-orf-1 ID=SMED30006431-orf-1|Name=SMED30006431-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=106bp
MTIIIRFVDIIKPLGSEIFEPAVIIREHFLGFVPLEETTGAFITETLIEK
LKQMELQIENLRGQRYNNGSNMKGKEKGVPKQHSKHKPASLFYSLQCTFF
KLSFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000136whole organism
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR025398DUF4371
IPR008906HATC_C_dom
IPR012337RNaseH-like_sf
Vocabulary: molecular function
TermDefinition
GO:0046983protein dimerization activity
GO:0003676nucleic acid binding