Short transient receptor potential channel 4
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30006424 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC4 (transient receptor potential cation channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:12336]) HSP 1 Score: 377.867 bits (969), Expect = 0.000e+0 Identity = 232/446 (52.02%), Postives = 319/446 (71.52%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG---LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNEN 1672
E+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++EL+ELLL +++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+ALASPSLIALSS+DP LTAF+LSWEL+ L ++ENEFK+EYE LS +C+ FA+ LL+QTR S EL I+LN+ R+ +SLI+ LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ F I +FP+ + YLI P+S ++KPFIKFICH++SY+ FL LL+LA+ I+ + L + +G PT++EW+++ ++ GFIW E+K++W+ G++ YI D WNL+DF NSLY+ATISL+ VA+ K S N
Sbjct: 33 EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY------------RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDL---NRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALN 463 HSP 2 Score: 308.916 bits (790), Expect = 0.000e+0 Identity = 157/321 (48.91%), Postives = 216/321 (67.29%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNE--------MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMT 2622
R WD + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + + TC + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYFE+G TLP PFN+I SPK+++YL W + LCK K ++ + S I + +YQ+VM NL+ RY+ + A+ EG+TE++ E+K DIS+FRFE+L +L+ + ++
Sbjct: 465 RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIR------------------CEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH-LCKKKMRR-KPESFGTIGVRTQHRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLS 765
BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC4 (transient receptor potential cation channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:12336]) HSP 1 Score: 377.867 bits (969), Expect = 0.000e+0 Identity = 232/446 (52.02%), Postives = 319/446 (71.52%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG---LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNEN 1672
E+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++EL+ELLL +++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+ALASPSLIALSS+DP LTAF+LSWEL+ L ++ENEFK+EYE LS +C+ FA+ LL+QTR S EL I+LN+ R+ +SLI+ LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ F I +FP+ + YLI P+S ++KPFIKFICH++SY+ FL LL+LA+ I+ + L + +G PT++EW+++ ++ GFIW E+K++W+ G++ YI D WNL+DF NSLY+ATISL+ VA+ K S N
Sbjct: 33 EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY------------RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDL---NRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALN 463 HSP 2 Score: 313.538 bits (802), Expect = 0.000e+0 Identity = 156/315 (49.52%), Postives = 217/315 (68.89%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK--SRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMT 2622
R WD + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + + TC + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYFE+G TLP PFN+I SPK+++YL W + LCK K ++ + +I + + +YQ+VM NL+ RY+ + A+ EG+TE++ E+K DIS+FRFE+L +L+ + ++
Sbjct: 465 RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIR------------------CEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH-LCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLS 760
BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC5 (transient receptor potential cation channel subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:12337]) HSP 1 Score: 377.867 bits (969), Expect = 0.000e+0 Identity = 231/438 (52.74%), Postives = 313/438 (71.46%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
E+ FL AVE+ D A++K+ L ++ NINC DPLGR+A+LIAIE E++E++ELLL + + +GDALL+AI +E AVE++++ + +++ T S FTPDITPI+LA+H +NYEIIKLL+ + IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEFKAEYE LS +C+ FA+ LL+Q R S EL I+LNH + + L+ + H LA+LK+AIKY+QK FVA P+CQQLLA+LWY+G PG+RR+ ++ K+ I +FPML+ YLI PRS +KKPFIKFICH++SY+ FL +L+LA+ I L +G PTV+EW+++ ++ GFIW E+KE+W+ G YI D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 EKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDD--HSEELDPQK------YHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLH---VQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVK 459 HSP 2 Score: 293.508 bits (750), Expect = 0.000e+0 Identity = 152/314 (48.41%), Postives = 213/314 (67.83%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKS--RWHSIKKIVSKVNE---MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA +NI S+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + ++ ++ K C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+ YL WF N C + R +++ + + Q YQ+V+ NL+ RY+ + ++ +EG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 466 REEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIR---------------CEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFN-NTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGN 763
BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC4 (transient receptor potential cation channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:12336]) HSP 1 Score: 377.096 bits (967), Expect = 0.000e+0 Identity = 232/446 (52.02%), Postives = 319/446 (71.52%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG---LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNEN 1672
E+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++EL+ELLL +++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+ALASPSLIALSS+DP LTAF+LSWEL+ L ++ENEFK+EYE LS +C+ FA+ LL+QTR S EL I+LN+ R+ +SLI+ LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ F I +FP+ + YLI P+S ++KPFIKFICH++SY+ FL LL+LA+ I+ + L + +G PT++EW+++ ++ GFIW E+K++W+ G++ YI D WNL+DF NSLY+ATISL+ VA+ K S N
Sbjct: 33 EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY------------RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDL---NRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALN 463 HSP 2 Score: 312.768 bits (800), Expect = 0.000e+0 Identity = 156/315 (49.52%), Postives = 217/315 (68.89%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK--SRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMT 2622
R WD + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + + TC + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYFE+G TLP PFN+I SPK+++YL W + LCK K ++ + +I + + +YQ+VM NL+ RY+ + A+ EG+TE++ E+K DIS+FRFE+L +L+ + ++
Sbjct: 465 RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIR------------------CEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH-LCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLS 760
BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC4 (transient receptor potential cation channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:12336]) HSP 1 Score: 376.711 bits (966), Expect = 0.000e+0 Identity = 232/446 (52.02%), Postives = 319/446 (71.52%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG---LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNEN 1672
E+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++EL+ELLL +++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+ALASPSLIALSS+DP LTAF+LSWEL+ L ++ENEFK+EYE LS +C+ FA+ LL+QTR S EL I+LN+ R+ +SLI+ LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ F I +FP+ + YLI P+S ++KPFIKFICH++SY+ FL LL+LA+ I+ + L + +G PT++EW+++ ++ GFIW E+K++W+ G++ YI D WNL+DF NSLY+ATISL+ VA+ K S N
Sbjct: 33 EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY------------RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDL---NRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALN 463 HSP 2 Score: 281.567 bits (719), Expect = 0.000e+0 Identity = 140/273 (51.28%), Postives = 188/273 (68.86%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK--SRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYL 2499
R WD + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + + TC + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYFE+G TLP PFN+I SPK+++YL W + LCK K ++ + +I + + +YQ+VM NL+ RY+
Sbjct: 465 RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIR------------------CEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH-LCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYV 718
BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: trp-2 (TRP (Transient receptor potential) channel family; TRP homlogous cation channel protein [Source:UniProtKB/TrEMBL;Acc:G5EE02]) HSP 1 Score: 377.096 bits (967), Expect = 4.682e-112 Identity = 235/469 (50.11%), Postives = 323/469 (68.87%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLS--SSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAM--FPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEY--NHLENDDY-----RGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIISWAGRNGIPTTQHL 1720
E+QFLL+ ER DI S+++ L FNINC DPLGRNA+LIAIE E+IE++ELLL ++++ GDA+L+AI EEN EAVEII+ +E D+ S ++ S+FTPDITPI+LA+H+DNYE IKL LD+ +P PHD+RC+C C ++++DSLR S+SRINAY+AL SPSLI LS++DPIL AFELSWELKRL +ENEF+ +YE LS KC+ F +L+Q RGS+EL ++LNH+ ++ + T + + + LARLKLAI+ +QK FVAHP+CQQLL +WYEG+ R F+YK +IF I M FP+ + +YL+ P S+ KKPFIKF+ HS SY+ FL+LLI+A+ R+ N L DD RG PT+IE + +++ G IW E+K+LWE G+ Y ++WN+LDF TNSLY+ T +LR VAY + E + + N + +HL
Sbjct: 34 EKQFLLSCERGDIGSVRKLLAGISTETFNINCLDPLGRNALLIAIENENIEMIELLLDHNIETGDAILYAIGEENVEAVEIIVE-HLEKMDKFDSERQGVEITEHSAFTPDITPIVLAAHKDNYECIKLFLDKKGTVPHPHDVRCSCPECYVAREEDSLRLSRSRINAYRALTSPSLICLSARDPILYAFELSWELKRLSFIENEFRTDYEELSQKCQKFCVHMLDQVRGSKELEVVLNHTTNAWHDVT-----SANYGNPEKLARLKLAIQLSQKRFVAHPNCQQLLLDIWYEGVESVRCTNFIYK--LIFYILGMLSFPLFSLVYLLAPHSSMGQFAKKPFIKFLSHSGSYIFFLILLIMASQRMNVIDNILRTDDVDRKETRGPPPTIIECAIFLWVLGLIWVEIKQLWECGLYNYCRNLWNILDFITNSLYLCTTALRVVAYVQVEQEALRA----NSVHIARHL 490 HSP 2 Score: 276.174 bits (705), Expect = 1.394e-77 Identity = 136/268 (50.75%), Postives = 190/268 (70.90%), Query Frame = 1
Query: 1681 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYY-LFFWFKMNCLCKSKGKKSRWHSIK--KIVSKVNEMEQRYQKVM 2475
+ R WD++DPTL+SEC FA ANIFS+LKLV+IFTV+P+LGPL+ISLGRM+ DI+KFF++Y LVL AFACGLNQLLW+YA R C+ + + +Y L C + K +S++ ++L+W+ +GLVDL++ L+ H +E+ GK +FG+Y ++IVLLNMLIAMM+ SYQ I++QADIEWKFARS+L++ YF+D TLP PFNI+ SPK+IYY L + K C C + S+ S++ KI+ VN+ E Y+K +
Sbjct: 490 LPRRDWDAWDPTLLSECFFATANIFSSLKLVHIFTVSPHLGPLKISLGRMVIDIVKFFMVYALVLFAFACGLNQLLWYYASMRQNECNLYEQYKNEKSLSYKYEHLKESCDDKYKSCSSIYHTAETLFWALFGLVDLTHFRLKEDHFLSEWTGKTIFGSYCCCSIIVLLNMLIAMMSNSYQYISDQADIEWKFARSRLFLEYFDDTATLPPPFNIVPSPKSIYYCLHYLTKKLCNCTKLQQPSKQKSMRNQKILRSVNDRENNYRKTI 757
BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: trp-2 (TRP (Transient receptor potential) channel family; TRP homlogous cation channel protein [Source:UniProtKB/TrEMBL;Acc:G5EE02]) HSP 1 Score: 376.711 bits (966), Expect = 2.987e-111 Identity = 235/469 (50.11%), Postives = 323/469 (68.87%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLS--SSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAM--FPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEY--NHLENDDY-----RGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIISWAGRNGIPTTQHL 1720
E+QFLL+ ER DI S+++ L FNINC DPLGRNA+LIAIE E+IE++ELLL ++++ GDA+L+AI EEN EAVEII+ +E D+ S ++ S+FTPDITPI+LA+H+DNYE IKL LD+ +P PHD+RC+C C ++++DSLR S+SRINAY+AL SPSLI LS++DPIL AFELSWELKRL +ENEF+ +YE LS KC+ F +L+Q RGS+EL ++LNH+ ++ + T + + + LARLKLAI+ +QK FVAHP+CQQLL +WYEG+ R F+YK +IF I M FP+ + +YL+ P S+ KKPFIKF+ HS SY+ FL+LLI+A+ R+ N L DD RG PT+IE + +++ G IW E+K+LWE G+ Y ++WN+LDF TNSLY+ T +LR VAY + E + + N + +HL
Sbjct: 34 EKQFLLSCERGDIGSVRKLLAGISTETFNINCLDPLGRNALLIAIENENIEMIELLLDHNIETGDAILYAIGEENVEAVEIIVE-HLEKMDKFDSERQGVEITEHSAFTPDITPIVLAAHKDNYECIKLFLDKKGTVPHPHDVRCSCPECYVAREEDSLRLSRSRINAYRALTSPSLICLSARDPILYAFELSWELKRLSFIENEFRTDYEELSQKCQKFCVHMLDQVRGSKELEVVLNHTTNAWHDVT-----SANYGNPEKLARLKLAIQLSQKRFVAHPNCQQLLLDIWYEGVESVRCTNFIYK--LIFYILGMLSFPLFSLVYLLAPHSSMGQFAKKPFIKFLSHSGSYIFFLILLIMASQRMNVIDNILRTDDVDRKETRGPPPTIIECAIFLWVLGLIWVEIKQLWECGLYNYCRNLWNILDFITNSLYLCTTALRVVAYVQVEQEALRA----NSVHIARHL 490 HSP 2 Score: 270.781 bits (691), Expect = 3.104e-75 Identity = 134/264 (50.76%), Postives = 187/264 (70.83%), Query Frame = 1
Query: 1681 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYY-LFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQK 2469
+ R WD++DPTL+SEC FA ANIFS+LKLV+IFTV+P+LGPL+ISLGRM+ DI+KFF++Y LVL AFACGLNQLLW+YA R C+ + + +Y L C + K +S++ ++L+W+ +GLVDL++ L+ H +E+ GK +FG+Y ++IVLLNMLIAMM+ SYQ I++QADIEWKFARS+L++ YF+D TLP PFNI+ SPK+IYY L + K C C + S+ S+ ++ SK + QR +K
Sbjct: 490 LPRRDWDAWDPTLLSECFFATANIFSSLKLVHIFTVSPHLGPLKISLGRMVIDIVKFFMVYALVLFAFACGLNQLLWYYASMRQNECNLYEQYKNEKSLSYKYEHLKESCDDKYKSCSSIYHTAETLFWALFGLVDLTHFRLKEDHFLSEWTGKTIFGSYCCCSIIVLLNMLIAMMSNSYQYISDQADIEWKFARSRLFLEYFDDTATLPPPFNIVPSPKSIYYCLHYLTKKLCNCTKLQQPSKQKSM-RVESKNLAIRQRPRK 752
BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: trp-1 (Transient-receptor-potential-like protein [Source:UniProtKB/Swiss-Prot;Acc:P34586]) HSP 1 Score: 251.906 bits (642), Expect = 2.693e-68 Identity = 164/448 (36.61%), Postives = 258/448 (57.59%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXHAINEENFEAVEIIIN-----AQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSY------MXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYY 1654
ER+FL A E + +++ LD N+NC D +GR A+ IA++ E++E++ELLL+ ALL AI E + VE+++N ++ + D + S+ ++ DI+P+ILA+ + +EI+++L+ + I KPH C C+ C + DSL++S RIN ++ALASP+ ++L+S DPIL+AF+LSW+L+RL E+EFK Y LS +C+ ++ LL Q R SEE+ +LN +N+ N D L+RLKLAIKY QK+FV+HPHCQQLL S+WYEG+P +R + + ++P+ +Y++ P+S L++ PF+KF +S S+ + + + E + RG T +E ++ ++ G +W E+K+LWE G K Y+ WN LDF LY+ TIS+R AYY
Sbjct: 50 ERRFLEAAELGNKPTLQECLDYDGDRRLNVNCLDSMGRTALEIAVDNENMEVVELLLQQPDIRIGNALLCAIREGVYRLVEVLVNHPNITREMLGDGWSQALDPSEAASAEYSSDISPVILAAQLNQFEILQMLIRKDASIEKPHRHSCICETCDRERLNDSLQYSLKRINTFRALASPAWMSLTSPDPILSAFKLSWDLQRLAFEEHEFKETYLQLSEQCKQYSCDLLSQCRSSEEVIAILNKDGN------VNDDNIDVWASKLSLSRLKLAIKYEQKAFVSHPHCQQLLTSIWYEGIPYRQRSGTWANFFLYAFLLFLWPIFCLMYILMPKSRLGRLVRSPFMKFFYYSVSFATFLGLLTWATFEDYRYEKGERGGMTRASDRGPPATWVESLVFTWVIGMLWSEIKQLWEEGFKRYMRQWWNWLDFLMICLYLCTISIRLSAYY 491 HSP 2 Score: 223.016 bits (567), Expect = 6.192e-59 Identity = 133/384 (34.64%), Postives = 212/384 (55.21%), Query Frame = 1
Query: 1519 IYLAGGQRVMGKWCQGIHHGYVEFIGLCH*FPLCSYN-QFESSRIL*IIK*KYYFMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNC--------LCKSKGKKSRWHSIKK---IVSKVNEMEQR------------YQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLD 2598
++ G +R M +W +++F+ +C LC+ + + + I + Y + R W S +P L++E LFA N+FS +++Y+F NP LGPLQISLG ML D+ KF I++L++ +F+ GL QL W+Y D LP C F+S+ + +L WS + + + ++ H+ T++VG+ MF Y ++IVLLNMLIAMM+ S+Q+I + AD+EWKF R+KLW+++F++G++LP PFNII++PK++ Y+ MNC L K +K+R + + K NEME+ Y ++ L+ R++ +K +GV EDDL+EIK DIS+ R+EL D
Sbjct: 455 LWEEGFKRYMRQWW-----NWLDFLMIC--LYLCTISIRLSAYYIFTYREDPYRYTVRTYWTSEEPMLVAEALFAVGNVFSFARIIYLFQTNPYLGPLQISLGCMLVDVAKFCFIFVLIISSFSIGLAQLYWYY---------DPNTDVCLPGAT---------CKHSSNVFSSIADSYLTLLWSLFSITKPEDTDVVENHKITQWVGQGMFIMYHCTSIIVLLNMLIAMMSHSFQIINDHADLEWKFHRTKLWMAHFDEGSSLPPPFNIIVTPKSLIYV-----MNCLFNTVRWLLGKYTYQKNRNRATIRRPGYSRKRNEMEKSGGHDDDSLKPLTYADIITRLVARFIHQTKKDMKMDGVNEDDLHEIKQDISSLRYELRD 808
BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: trp-1 (Transient-receptor-potential-like protein [Source:UniProtKB/Swiss-Prot;Acc:P34586]) HSP 1 Score: 247.669 bits (631), Expect = 7.989e-67 Identity = 162/446 (36.32%), Postives = 256/446 (57.40%), Query Frame = 2
Query: 353 QFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXHAINEENFEAVEIIIN-----AQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSY------MXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYY 1654
+FL A E + +++ LD N+NC D +GR A+ IA++ E++E++ELLL+ ALL AI E + VE+++N ++ + D + S+ ++ DI+P+ILA+ + +EI+++L+ + I KPH C C+ C + DSL++S RIN ++ALASP+ ++L+S DPIL+AF+LSW+L+RL E+EFK Y LS +C+ ++ LL Q R SEE+ +LN +N+ N D L+RLKLAIKY QK+FV+HPHCQQLL S+WYEG+P +R + + ++P+ +Y++ P+S L++ PF+KF +S S+ + + + E + RG T +E ++ ++ G +W E+K+LWE G K Y+ WN LDF LY+ TIS+R AYY
Sbjct: 72 RFLEAAELGNKPTLQECLDYDGDRRLNVNCLDSMGRTALEIAVDNENMEVVELLLQQPDIRIGNALLCAIREGVYRLVEVLVNHPNITREMLGDGWSQALDPSEAASAEYSSDISPVILAAQLNQFEILQMLIRKDASIEKPHRHSCICETCDRERLNDSLQYSLKRINTFRALASPAWMSLTSPDPILSAFKLSWDLQRLAFEEHEFKETYLQLSEQCKQYSCDLLSQCRSSEEVIAILNKDGN------VNDDNIDVWASKLSLSRLKLAIKYEQKAFVSHPHCQQLLTSIWYEGIPYRQRSGTWANFFLYAFLLFLWPIFCLMYILMPKSRLGRLVRSPFMKFFYYSVSFATFLGLLTWATFEDYRYEKGERGGMTRASDRGPPATWVESLVFTWVIGMLWSEIKQLWEEGFKRYMRQWWNWLDFLMICLYLCTISIRLSAYY 511 HSP 2 Score: 223.402 bits (568), Expect = 5.315e-59 Identity = 133/384 (34.64%), Postives = 212/384 (55.21%), Query Frame = 1
Query: 1519 IYLAGGQRVMGKWCQGIHHGYVEFIGLCH*FPLCSYN-QFESSRIL*IIK*KYYFMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNC--------LCKSKGKKSRWHSIKK---IVSKVNEMEQR------------YQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLD 2598
++ G +R M +W +++F+ +C LC+ + + + I + Y + R W S +P L++E LFA N+FS +++Y+F NP LGPLQISLG ML D+ KF I++L++ +F+ GL QL W+Y D LP C F+S+ + +L WS + + + ++ H+ T++VG+ MF Y ++IVLLNMLIAMM+ S+Q+I + AD+EWKF R+KLW+++F++G++LP PFNII++PK++ Y+ MNC L K +K+R + + K NEME+ Y ++ L+ R++ +K +GV EDDL+EIK DIS+ R+EL D
Sbjct: 475 LWEEGFKRYMRQWW-----NWLDFLMIC--LYLCTISIRLSAYYIFTYREDPYRYTVRTYWTSEEPMLVAEALFAVGNVFSFARIIYLFQTNPYLGPLQISLGCMLVDVAKFCFIFVLIISSFSIGLAQLYWYY---------DPNTDVCLPGAT---------CKHSSNVFSSIADSYLTLLWSLFSITKPEDTDVVENHKITQWVGQGMFIMYHCTSIIVLLNMLIAMMSHSFQIINDHADLEWKFHRTKLWMAHFDEGSSLPPPFNIIVTPKSLIYV-----MNCLFNTVRWLLGKYTYQKNRNRATIRRPGYSRKRNEMEKSGGHDDDSLKPLTYADIITRLVARFIHQTKKDMKMDGVNEDDLHEIKQDISSLRYELRD 828
BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: spe-41 (TRP homologous cation channel protein; TRP-3 channel protein [Source:UniProtKB/TrEMBL;Acc:G5EF09]) HSP 1 Score: 62.003 bits (149), Expect = 5.277e-19 Identity = 50/233 (21.46%), Postives = 98/233 (42.06%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVG------------------KLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIII 2331
R W S++ +L+ E A A + S LK Y + ++G IS+G+ + + LI + ++V+F+ GLN ++ Y + D +Y T Y T + ++L+WS +G + P FT VG +++ Y I +I +LN++ +++ + + ++E+KF R+ ++ + P P N+I+
Sbjct: 465 RMHWPSFEFSLLHEICLAIACVLSILKCFYYAQMMKSIGGSVISVGKCVGKTYTYILIMVAIIVSFSVGLNIIVDPYLNRSTMKIGDQ-----------------DYTKTTDSYET-IGTSSKNLFWSIFGYLG--------PSTFTTVVGNTGPNMDPVKHTLNSSTFEILAAVYHGILIITVLNLMTSILVKGADEVLDNEEMEFKFTRAAIYSEFLSWEMAAPPPLNLIL 671 HSP 2 Score: 53.5286 bits (127), Expect = 5.277e-19 Identity = 69/323 (21.36%), Postives = 131/323 (40.56%), Query Frame = 2
Query: 653 SSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTA-FELSWELKRLGRLEN-EFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASL----WYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFA 1603
S F P +TP++LA +N+ I++ L+ RG I PH + C C C +++ HS +R+ S + D + A ++ +L++L + E+ Y L + F + +Q +E +++ +N ++ + E ++ RL++A+ + F + Q + S+ WY +R + + I + P L ++ P T M P +FI H + Y++FL+ IL I + D T +E + Y+ G ++ + G G+ W D A
Sbjct: 137 SPHFPPHMTPLMLACILNNFSIVQCLITRGHCIQIPHFITCECKTC---KRETVTTHSSTRLVDVMRALSSEAYLWLATDDVFAATCAVARDLQQLASDDQLEYVETYRDLEMNVQRFLCRISDQAWRVDEFNMMV--ANRNYCPERMTEISS---------PRLQMAMDSQMRQFTCSTNSQTTIKSVFRSDWYNYGIKPKRDAWRFLRACI-----LMPFLVMLHAFMP--TKGTTMCVPLARFIAHITMYLVFLIAAILRPT-IGFYFAWTDSIE-VTVQALEIFMYAYVMGLALEKGILFYRVGRDGFFAFWWRWFDAA 436
BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: Trpgamma (gene:FBgn0032593 transcript:FBtr0080945) HSP 1 Score: 412.149 bits (1058), Expect = 0.000e+0 Identity = 249/465 (53.55%), Postives = 330/465 (70.97%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGF-NINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQ-IEVHDQ-KPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG----LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIE--------------YNHLEN-DDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENI 1675
E++FLLAVER D+A +R L +Q T + N+NC DPLGR A+L+AI+ E++E++ELL+ Y++D DALLH+I+EE EAVE++++ + + H + S + S +S+FTPDITP+ILA+HRDNYEIIK+LLDRG +P PHD+RC CD CV+S+++DSLRHS+SRINAY+ALASPSLIALSSKDPILTAFELSWEL+RL LE+EFK EY+ L +C+DFA ALL+ TR S EL ILLNH + + HG L RLKLAIK QK FVAH + QQLLAS+WYEGLPGFRR+ + I I MFP+ + Y++ P S+ M+KPFIKFICHS+SY FL LL+LA+ RIE N +E RG PT IEW+++ +++G IW EVK+LW+ G++ Y+ DMWN++DF TNSLYVAT++LR V++++ E I
Sbjct: 21 EKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNH-------------DPTGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMI 472 HSP 2 Score: 352.443 bits (903), Expect = 0.000e+0 Identity = 169/316 (53.48%), Postives = 229/316 (72.47%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWF-KMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNV 2631
R +WD++DP LISE LF+AANIFS+LKLVYIF+VNP+LGPLQ+SL RM+ DIMKFF +Y+LVL AF GLNQLLW+YA + C + L N + + N C + F++LFE Q+L+W+ +GL+DL + L+ FT F G LMFGTYS I ++VLLN+LIAMMN SYQLI+E+AD+EWKFARSKLWISYFE+G T P PFNII +PK+I+Y W ++ C S ++ +I++ + ++ + +YQ++M NL+ RY+ Q+ +++GVTEDD+NEIK DISAFR EL++ILKN+GM NV
Sbjct: 482 RERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDP--NACIV-WRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVEILKNSGMDTNV 794
BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: Trpgamma (gene:FBgn0032593 transcript:FBtr0335144) HSP 1 Score: 412.149 bits (1058), Expect = 0.000e+0 Identity = 249/465 (53.55%), Postives = 330/465 (70.97%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGF-NINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQ-IEVHDQ-KPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG----LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIE--------------YNHLEN-DDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENI 1675
E++FLLAVER D+A +R L +Q T + N+NC DPLGR A+L+AI+ E++E++ELL+ Y++D DALLH+I+EE EAVE++++ + + H + S + S +S+FTPDITP+ILA+HRDNYEIIK+LLDRG +P PHD+RC CD CV+S+++DSLRHS+SRINAY+ALASPSLIALSSKDPILTAFELSWEL+RL LE+EFK EY+ L +C+DFA ALL+ TR S EL ILLNH + + HG L RLKLAIK QK FVAH + QQLLAS+WYEGLPGFRR+ + I I MFP+ + Y++ P S+ M+KPFIKFICHS+SY FL LL+LA+ RIE N +E RG PT IEW+++ +++G IW EVK+LW+ G++ Y+ DMWN++DF TNSLYVAT++LR V++++ E I
Sbjct: 82 EKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNH-------------DPTGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMI 533 HSP 2 Score: 352.829 bits (904), Expect = 0.000e+0 Identity = 169/316 (53.48%), Postives = 229/316 (72.47%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWF-KMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNV 2631
R +WD++DP LISE LF+AANIFS+LKLVYIF+VNP+LGPLQ+SL RM+ DIMKFF +Y+LVL AF GLNQLLW+YA + C + L N + + N C + F++LFE Q+L+W+ +GL+DL + L+ FT F G LMFGTYS I ++VLLN+LIAMMN SYQLI+E+AD+EWKFARSKLWISYFE+G T P PFNII +PK+I+Y W ++ C S ++ +I++ + ++ + +YQ++M NL+ RY+ Q+ +++GVTEDD+NEIK DISAFR EL++ILKN+GM NV
Sbjct: 543 RERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDP--NACIV-WRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVEILKNSGMDTNV 855
BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: Trpgamma (gene:FBgn0032593 transcript:FBtr0080946) HSP 1 Score: 412.149 bits (1058), Expect = 0.000e+0 Identity = 249/465 (53.55%), Postives = 330/465 (70.97%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGF-NINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQ-IEVHDQ-KPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG----LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIE--------------YNHLEN-DDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENI 1675
E++FLLAVER D+A +R L +Q T + N+NC DPLGR A+L+AI+ E++E++ELL+ Y++D DALLH+I+EE EAVE++++ + + H + S + S +S+FTPDITP+ILA+HRDNYEIIK+LLDRG +P PHD+RC CD CV+S+++DSLRHS+SRINAY+ALASPSLIALSSKDPILTAFELSWEL+RL LE+EFK EY+ L +C+DFA ALL+ TR S EL ILLNH + + HG L RLKLAIK QK FVAH + QQLLAS+WYEGLPGFRR+ + I I MFP+ + Y++ P S+ M+KPFIKFICHS+SY FL LL+LA+ RIE N +E RG PT IEW+++ +++G IW EVK+LW+ G++ Y+ DMWN++DF TNSLYVAT++LR V++++ E I
Sbjct: 21 EKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNH-------------DPTGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMI 472 HSP 2 Score: 352.443 bits (903), Expect = 0.000e+0 Identity = 169/316 (53.48%), Postives = 229/316 (72.47%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWF-KMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNV 2631
R +WD++DP LISE LF+AANIFS+LKLVYIF+VNP+LGPLQ+SL RM+ DIMKFF +Y+LVL AF GLNQLLW+YA + C + L N + + N C + F++LFE Q+L+W+ +GL+DL + L+ FT F G LMFGTYS I ++VLLN+LIAMMN SYQLI+E+AD+EWKFARSKLWISYFE+G T P PFNII +PK+I+Y W ++ C S ++ +I++ + ++ + +YQ++M NL+ RY+ Q+ +++GVTEDD+NEIK DISAFR EL++ILKN+GM NV
Sbjct: 482 RERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDP--NACIV-WRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVEILKNSGMDTNV 794
BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: trpl (gene:FBgn0005614 transcript:FBtr0088471) HSP 1 Score: 326.25 bits (835), Expect = 2.762e-170 Identity = 200/452 (44.25%), Postives = 299/452 (66.15%), Query Frame = 2
Query: 365 AVERSDIASIKRFLDSSQK-TGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQ-KPSTDYTSNLSSS-FTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHL--------------ENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNE 1669
AVER D+ +++R L + + NINC DPLGR A+ +AI+ E++E++ELL+ ++ DALLHAIN E EAVE+++ + ++ + +P + +++++ F PDITP++LA+H++N+EI+++LLDRG +P PHD+RC C+ CV +DSLRHS SR+N Y+AL SPSLI L+S DPI+TAF+LSWEL+ L E E K+EY L +C+ FA LL+QTR S ELAI+LN+ + ++ D L RL AI Y QK FVAH + QQLL+S+WY+GLPGFRR+ + KV I ++ +FP+ IY+ P LM+KPF+KF+ H+SSY+ FL +LIL + R + + + + RG TP+ +E I+++Y+ GF+W+EV+E++ G+K Y+ +MWN +DF NSLYV+ + LRA AY + + E
Sbjct: 48 AVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMGVETKDALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKVDINTAMFAPDITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPSLICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNYD---------PQMSSYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTTRMKKELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATE 490 HSP 2 Score: 295.049 bits (754), Expect = 2.762e-170 Identity = 150/317 (47.32%), Postives = 205/317 (64.67%), Query Frame = 1
Query: 1678 FMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVN 2628
++ R KW +DP LI+E LFAAAN+FS LKLV++F++NP+LGPLQISLGRM+ DI+KFF IY LVL AFACGLNQLLW++A C Y LP + C + + F +LFE QSL+W+++G+V L + L +T F G LMFG+YS I +IVLLN+LIAMM+ SY +I E +D EWKFAR+KLW+SYFED TLP PFN++ S K + +F KS R S K+ K E Y +M +L+ RY+ + +N V+EDD+NE+K +I+ R+E+L+I +N+GM V+
Sbjct: 499 YIPREKWHDFDPQLIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSKC------YVLPGGEADWGSHGDSC-MKWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLPSVKWVIRIFR--------KSSKTIDRQRSKKR---KEQEQFSEYDNIMRSLVWRYVAAMHRKFENNPVSEDDINEVKSEINTMRYEMLEIFENSGMDVS 797
BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: trpl (gene:FBgn0005614 transcript:FBtr0301662) HSP 1 Score: 326.25 bits (835), Expect = 2.762e-170 Identity = 200/452 (44.25%), Postives = 299/452 (66.15%), Query Frame = 2
Query: 365 AVERSDIASIKRFLDSSQK-TGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQ-KPSTDYTSNLSSS-FTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHL--------------ENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNE 1669
AVER D+ +++R L + + NINC DPLGR A+ +AI+ E++E++ELL+ ++ DALLHAIN E EAVE+++ + ++ + +P + +++++ F PDITP++LA+H++N+EI+++LLDRG +P PHD+RC C+ CV +DSLRHS SR+N Y+AL SPSLI L+S DPI+TAF+LSWEL+ L E E K+EY L +C+ FA LL+QTR S ELAI+LN+ + ++ D L RL AI Y QK FVAH + QQLL+S+WY+GLPGFRR+ + KV I ++ +FP+ IY+ P LM+KPF+KF+ H+SSY+ FL +LIL + R + + + + RG TP+ +E I+++Y+ GF+W+EV+E++ G+K Y+ +MWN +DF NSLYV+ + LRA AY + + E
Sbjct: 48 AVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMGVETKDALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKVDINTAMFAPDITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPSLICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNYD---------PQMSSYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTTRMKKELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATE 490 HSP 2 Score: 295.049 bits (754), Expect = 2.762e-170 Identity = 150/317 (47.32%), Postives = 205/317 (64.67%), Query Frame = 1
Query: 1678 FMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVN 2628
++ R KW +DP LI+E LFAAAN+FS LKLV++F++NP+LGPLQISLGRM+ DI+KFF IY LVL AFACGLNQLLW++A C Y LP + C + + F +LFE QSL+W+++G+V L + L +T F G LMFG+YS I +IVLLN+LIAMM+ SY +I E +D EWKFAR+KLW+SYFED TLP PFN++ S K + +F KS R S K+ K E Y +M +L+ RY+ + +N V+EDD+NE+K +I+ R+E+L+I +N+GM V+
Sbjct: 499 YIPREKWHDFDPQLIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSKC------YVLPGGEADWGSHGDSC-MKWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLPSVKWVIRIFR--------KSSKTIDRQRSKKR---KEQEQFSEYDNIMRSLVWRYVAAMHRKFENNPVSEDDINEVKSEINTMRYEMLEIFENSGMDVS 797
BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Match: trpc4b (transient receptor potential cation channel, subfamily C, member 4b [Source:ZFIN;Acc:ZDB-GENE-120329-1]) HSP 1 Score: 374.015 bits (959), Expect = 0.000e+0 Identity = 231/441 (52.38%), Postives = 313/441 (70.98%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSN 1666
E+ +L AVE+ D AS+K L+ ++ NINC DPLGR A+LIAIE E++E++ELLL +++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIK+L+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+ALASPSLIALSS+DP LTAF+LSWEL+ L ++ENEFKAEYE LS +C+ FA+ LL+QTR S EL ++LN + N +E N + LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ I MFP+L+ YL+ P+S + ++KPFIKFICH++SY+ FL LL+LA+ I N N D +G PT +EW+++ ++ GFIW E+K++W+ G + YI D WNL+DF NSLY+ATISL+ VAY K S
Sbjct: 33 EKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNFRDD--MNLLQDEANNE-------LARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIVSN---NPDRQGPKPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSG 461 HSP 2 Score: 307.76 bits (787), Expect = 0.000e+0 Identity = 150/310 (48.39%), Postives = 211/310 (68.06%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNN 2613
R W+ + PTL++E +FA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y TC + C + F++LFE +QSL+WS +GL+ L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQ IA+ ADIEWKFAR+KLW+SYFE+G TLP PFNII SPK+I YL W K++ + +K + ++ + ++ + +YQ+V+ NL+ RY+ + A+ EG+TE++ E+K DIS+FR+E++ ++K N
Sbjct: 465 RDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIR------------------CERQNNAFSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLITWIKVHVFKRRSKRKETFGTLGRRAAENVRLNHQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVIGMMKGN 756
BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Match: trpc4b (transient receptor potential cation channel, subfamily C, member 4b [Source:ZFIN;Acc:ZDB-GENE-120329-1]) HSP 1 Score: 374.015 bits (959), Expect = 0.000e+0 Identity = 231/441 (52.38%), Postives = 313/441 (70.98%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSN 1666
E+ +L AVE+ D AS+K L+ ++ NINC DPLGR A+LIAIE E++E++ELLL +++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIK+L+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+ALASPSLIALSS+DP LTAF+LSWEL+ L ++ENEFKAEYE LS +C+ FA+ LL+QTR S EL ++LN + N +E N + LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ I MFP+L+ YL+ P+S + ++KPFIKFICH++SY+ FL LL+LA+ I N N D +G PT +EW+++ ++ GFIW E+K++W+ G + YI D WNL+DF NSLY+ATISL+ VAY K S
Sbjct: 33 EKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNFRDD--MNLLQDEANNE-------LARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIVSN---NPDRQGPKPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSG 461 HSP 2 Score: 307.76 bits (787), Expect = 0.000e+0 Identity = 150/310 (48.39%), Postives = 211/310 (68.06%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNN 2613
R W+ + PTL++E +FA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y TC + C + F++LFE +QSL+WS +GL+ L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQ IA+ ADIEWKFAR+KLW+SYFE+G TLP PFNII SPK+I YL W K++ + +K + ++ + ++ + +YQ+V+ NL+ RY+ + A+ EG+TE++ E+K DIS+FR+E++ ++K N
Sbjct: 465 RDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIR------------------CERQNNAFSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLITWIKVHVFKRRSKRKETFGTLGRRAAENVRLNHQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVIGMMKGN 756
BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Match: trpc5a (transient receptor potential cation channel, subfamily C, member 5a [Source:ZFIN;Acc:ZDB-GENE-040812-1]) HSP 1 Score: 372.474 bits (955), Expect = 0.000e+0 Identity = 229/439 (52.16%), Postives = 313/439 (71.30%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNI--NCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER FL AVE+ D A ++ L ++ +NI NC DPLGR+A+LIAIE E++E++ELLL + ++ GDALL+AI +E AVE++++ + +++ + S FTPDITPI+LA+H +NYEIIKLL+ R IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEF+ EYE LS +C+ FA+ LL+Q R S EL +LNH + + L+ R + LA+LKLAIKY+QK FVA P+CQQLLA+LWY+G PG+RRR + K+ M F I +FP+ + +YL+ P+ST +KKPFIKFICH++SY+ FL LL+LA+ I +L +G PTV+EW+++ ++ GFIW E+KE+W+ G Y+ D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 58 ERAFLSAVEKGDYAGVQHALREAE-VYYNIDTNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPSLMMDAQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRDD--QSEELDPR------ECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCFIIGLLFPVFSLVYLLAPKSTLGLFIKKPFIKFICHTASYLTFLFLLLLASQHIARTNLH---MQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVK 484 HSP 2 Score: 298.13 bits (762), Expect = 0.000e+0 Identity = 157/317 (49.53%), Postives = 216/317 (68.14%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK-----SRWHSIKKIVSKVNE---MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y ET + D+ + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+ +YL W LC S+ + ++K+ K + Q YQ+V+ +L+ RY+ + A+ +EG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 491 REEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYY-----ETEAADEPNHCKGIR----------CERQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFWYLCRWVHGR-LCGSETAPPEEDTHKHENLKEFTEKHADRLIQNQHYQEVIRSLVKRYVASMIRSAKTSEGLTEENFKELKQDISSFRYEVLDLLGN 791
BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Match: trpc5b (transient receptor potential cation channel, subfamily C, member 5b [Source:ZFIN;Acc:ZDB-GENE-091112-24]) HSP 1 Score: 372.089 bits (954), Expect = 0.000e+0 Identity = 229/439 (52.16%), Postives = 313/439 (71.30%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNI--NCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER FL AVE+ D A ++ L ++ +NI NC DPLGR+A+LIAIE E++E++ELLL + ++ GDALL+AI +E AVE++++ + +++ + S FTPDITPI+LA+H +NYEIIKLL+ R IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEF+ EYE LS +C+ FA+ LL+Q R S EL +LNH + + L+ R + LA+LKLAIKY+QK FVA P+CQQLLA+LWY+G PG+RRR + K+ M F I +FP+ + +YL+ P+ST +KKPFIKFICH++SY+ FL LL+LA+ I +L +G PTV+EW+++ ++ GFIW E+KE+W+ G Y+ D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 ERAFLSAVEKGDYAGVQHALREAE-VYYNIDTNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPSLMMDAQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRDD--QSEELDPR------ECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCFIIGLLFPVFSLVYLLAPKSTLGLFIKKPFIKFICHTASYLTFLFLLLLASQHIARTNLH---MQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVK 459 HSP 2 Score: 292.738 bits (748), Expect = 0.000e+0 Identity = 155/315 (49.21%), Postives = 211/315 (66.98%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKK------IVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y ET + D+ + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+ +YL W LC S+ + K V K + +V+ +L+ RY+ + A+ +EG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 466 REEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYY-----ETEAADEPNHCKGIR----------CERQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFWYLCRWVHGR-LCGSETAPPEEDTHKHENLKEFTVKKAVRIHLNIVEVIRSLVKRYVASMIRSAKTSEGLTEENFKELKQDISSFRYEVLDLLGN 764
BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Match: trpc5a (transient receptor potential cation channel, subfamily C, member 5a [Source:ZFIN;Acc:ZDB-GENE-040812-1]) HSP 1 Score: 372.089 bits (954), Expect = 0.000e+0 Identity = 229/439 (52.16%), Postives = 313/439 (71.30%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNI--NCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER FL AVE+ D A ++ L ++ +NI NC DPLGR+A+LIAIE E++E++ELLL + ++ GDALL+AI +E AVE++++ + +++ + S FTPDITPI+LA+H +NYEIIKLL+ R IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEF+ EYE LS +C+ FA+ LL+Q R S EL +LNH + + L+ R + LA+LKLAIKY+QK FVA P+CQQLLA+LWY+G PG+RRR + K+ M F I +FP+ + +YL+ P+ST +KKPFIKFICH++SY+ FL LL+LA+ I +L +G PTV+EW+++ ++ GFIW E+KE+W+ G Y+ D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 ERAFLSAVEKGDYAGVQHALREAE-VYYNIDTNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPSLMMDAQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRDD--QSEELDPR------ECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCFIIGLLFPVFSLVYLLAPKSTLGLFIKKPFIKFICHTASYLTFLFLLLLASQHIARTNLH---MQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVK 459 HSP 2 Score: 298.516 bits (763), Expect = 0.000e+0 Identity = 157/317 (49.53%), Postives = 216/317 (68.14%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK-----SRWHSIKKIVSKVNE---MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y ET + D+ + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+ +YL W LC S+ + ++K+ K + Q YQ+V+ +L+ RY+ + A+ +EG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 466 REEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYY-----ETEAADEPNHCKGIR----------CERQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFWYLCRWVHGR-LCGSETAPPEEDTHKHENLKEFTEKHADRLIQNQHYQEVIRSLVKRYVASMIRSAKTSEGLTEENFKELKQDISSFRYEVLDLLGN 766
BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: TRPC5 (transient receptor potential cation channel, subfamily C, member 5 [Source:NCBI gene;Acc:100493720]) HSP 1 Score: 380.178 bits (975), Expect = 0.000e+0 Identity = 230/438 (52.51%), Postives = 314/438 (71.69%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
E+ +L+AVE+ D AS+K L+ ++ NINC DPLGR+A+LIAIE E++E++ELLL +++ +GDALL+AI +E AVE++++ + +++ T S FTPDITPI+LA+H +NYEIIKLL+ R IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEFKAEYE LS +C+ FA+ LL+Q R S EL I+LNH + + L+ + H LA+LK+AIKY+QK FVA P+CQQLLA+LWY+G PG+RR+ + K+ I +FP+L+ YLI P+S +KKPFIKFICH++SY+ FL LL+LA+ I L +G PTV+EW+++ ++ GFIW E+KE+W+ G Y+ D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 EKAYLIAVEKGDYASVKHALEEAEIYYNININCMDPLGRSALLIAIENENLEIMELLLSHNIYVGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQRRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKKFAKDLLDQARSSRELEIILNHRDD--QSEELDPQKC------HDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWAVKLVTCITIGLLFPVLSVAYLIAPKSRLGLFIKKPFIKFICHTASYLTFLFLLLLASQHIVRTELH---MQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVK 459 HSP 2 Score: 298.13 bits (762), Expect = 0.000e+0 Identity = 156/316 (49.37%), Postives = 215/316 (68.04%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK---SRWHSIKKIVSKVNE----MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +WD + PTLI+E FA +NI S+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y ET + ++ P N C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G T+P PFNII SPK+I+Y W + LC K + + H K ++ + Q YQ+V+ NL+ RY+ + ++ NEG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 466 REEWDMWHPTLIAEAFFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYY-----ETSASEE-----PNNCKGIR-----CEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGATMPPPFNIIASPKSIWYFCKWVRYK-LCPGKNSEEDIQKQHENLKTFTERHADNLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDLLGN 765
BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: hint1 (histidine triad nucleotide binding protein 1 [Source:Xenbase;Acc:XB-GENE-1014427]) HSP 1 Score: 374.785 bits (961), Expect = 0.000e+0 Identity = 227/440 (51.59%), Postives = 314/440 (71.36%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG--LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
E+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++EL+ELLL Y++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIK L+ +G +P+PH++RC C CV DSLRHS+SR+N Y+AL+SPSLIALSS+DP LTAF+LSWEL+ L ++ENEFK+EYE LS++C+ FA+ LL+QTR S EL I+LN+ + + L D++G LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR ++ K+ + +FP + YLI P+STF ++KPFIKFICH++SY+ FL LL+LA+ I + + +G PT++EW+++ ++ GFIW E+K++W+ G + YI D WNL+DF NSLY+ATISL+ VAY K
Sbjct: 33 EKAYLSAVEKGDYASVKQALEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSYNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKHLVQKGVSVPRPHEVRCNCVECVSGSDVDSLRHSRSRLNIYRALSSPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSSQCKQFAKDLLDQTRSSRELEIILNYRD-----------DGGLLDDSNGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWVVKMVTCVIVGLLFPAFSCCYLIAPKSTFGLFIRKPFIKFICHTASYLTFLFLLLLASQNIN----KTESLQGPAPTIVEWMILPWVLGFIWGEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVK 457 HSP 2 Score: 312.768 bits (800), Expect = 0.000e+0 Identity = 159/321 (49.53%), Postives = 214/321 (66.67%), Query Frame = 1
Query: 1672 YYFMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFY-AKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWF-KMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTV 2625
Y R +W+ + PTL++E +FA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y A + C + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYFE+G TLP PFNII SPK+++YL W K C K K K + +I + + YQ+VM NL+ RY+ + A+ EG+TE++ E+K DIS+FRFE+L +LK N +
Sbjct: 455 YVKRNRAEWEMFHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEADAKSSDCKGIR------------------CEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVDPKHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNIIPSPKSLWYLIKWIRKQICKKKMKRKPESFGAIGRRAADNLRRHNHYQEVMKNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLKGNKFNI 757
BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: TRPC1 (transient receptor potential cation channel, subfamily C, member 1 [Source:NCBI gene;Acc:100497011]) HSP 1 Score: 278.87 bits (712), Expect = 4.267e-132 Identity = 186/441 (42.18%), Postives = 281/441 (63.72%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPS----TDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER FLLA E+ D +K+ L+ + NIN D LGRNAI I+IE E++++L+LLL Y DALL AI+ E AV+I++N Q + +P+ + N S T D+ P+ILA+HR+NYEI+ +LL + +PKPH + C C +C K+DSLRHS+ R++ Y+ LASP+LI L+ +DPIL AFELS +LK L +E EF+ +YE L+ KC+ FA+ LL Q R S EL ++LNH + S+ +++R L + L+RLKLAIKYNQK FV+ +CQQ L ++W+ + G+RR+ K+ ++ + +P+L+ YL+ P+S ++ PF+KFI H +SY FLLLL L +L YN + + G I+++LI+++ G +W +VK LW +G++ ++ + N L F NSLY+AT +L+ VA+ K
Sbjct: 151 ERLFLLACEKGDYYMVKKLLEENSSEELNINSVDVLGRNAITISIENENLDILQLLLNYGCQSTDALLVAIDSEVVGAVDILLNHQPKWRT-RPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCTAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELAQKCKTFAKDLLAQARNSRELEVILNHQS---SDEPVDKRGL--LEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMAGYRRKHTCKKILIVLTVGIFWPVLSVCYLLAPKSQVGRIIHTPFMKFIIHGASYFTFLLLLNLYSLV--YNE-DKKNTMGPALERIDFLLIMWLIGMVWSDVKRLWYDGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNK 582 HSP 2 Score: 216.468 bits (550), Expect = 4.267e-132 Identity = 124/310 (40.00%), Postives = 184/310 (59.35%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGL--VDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWF-KMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLH-RQKAEDNEGVTEDDLNEIKGDISAFRFELLDIL 2604
R WD++ PTL++E LFA N+ S L+L +++T + LGPLQIS+G+ML D KF +++LVL +F GL QL Y K T ++ K+ + S + +++ T +L+W + L V L + + FVG L+ GTY+ + +IVL +L+AM++ S+QLIA D EWKFAR+KLW+SYF+D TLP PFNI+ SPKTI YLF K C + G+ R +S+K+ S + ++ YQKVM L+ RYL RQK + + T ++LNE++ D+S FR E+ D+L
Sbjct: 589 RKDWDAFHPTLVAEGLFAFGNVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQL---YDKGY--TTNEQKDCVGIFCEQQSNDAFHSFTGT-----------CYALFWYIFSLAHVALFVTRFSFSEELQSFVGALIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIVPSPKTICYLFNSISKWICSHTTTGRVKRQNSLKEWKSLRQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEMRDLL 882
BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: TRPC1 (transient receptor potential cation channel, subfamily C, member 1 [Source:NCBI gene;Acc:100497011]) HSP 1 Score: 278.485 bits (711), Expect = 7.329e-132 Identity = 186/441 (42.18%), Postives = 281/441 (63.72%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPS----TDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER FLLA E+ D +K+ L+ + NIN D LGRNAI I+IE E++++L+LLL Y DALL AI+ E AV+I++N Q + +P+ + N S T D+ P+ILA+HR+NYEI+ +LL + +PKPH + C C +C K+DSLRHS+ R++ Y+ LASP+LI L+ +DPIL AFELS +LK L +E EF+ +YE L+ KC+ FA+ LL Q R S EL ++LNH + S+ +++R L + L+RLKLAIKYNQK FV+ +CQQ L ++W+ + G+RR+ K+ ++ + +P+L+ YL+ P+S ++ PF+KFI H +SY FLLLL L +L YN + + G I+++LI+++ G +W +VK LW +G++ ++ + N L F NSLY+AT +L+ VA+ K
Sbjct: 66 ERLFLLACEKGDYYMVKKLLEENSSEELNINSVDVLGRNAITISIENENLDILQLLLNYGCQSTDALLVAIDSEVVGAVDILLNHQPKWR-TRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCTAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELAQKCKTFAKDLLAQARNSRELEVILNHQS---SDEPVDKRGL--LEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMAGYRRKHTCKKILIVLTVGIFWPVLSVCYLLAPKSQVGRIIHTPFMKFIIHGASYFTFLLLLNLYSLV--YNE-DKKNTMGPALERIDFLLIMWLIGMVWSDVKRLWYDGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNK 497 HSP 2 Score: 215.698 bits (548), Expect = 7.329e-132 Identity = 124/310 (40.00%), Postives = 184/310 (59.35%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGL--VDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWF-KMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLH-RQKAEDNEGVTEDDLNEIKGDISAFRFELLDIL 2604
R WD++ PTL++E LFA N+ S L+L +++T + LGPLQIS+G+ML D KF +++LVL +F GL QL Y K T ++ K+ + S + +++ T +L+W + L V L + + FVG L+ GTY+ + +IVL +L+AM++ S+QLIA D EWKFAR+KLW+SYF+D TLP PFNI+ SPKTI YLF K C + G+ R +S+K+ S + ++ YQKVM L+ RYL RQK + + T ++LNE++ D+S FR E+ D+L
Sbjct: 504 RKDWDAFHPTLVAEGLFAFGNVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQL---YDKGY--TTNEQKDCVGIFCEQQSNDAFHSFTGT-----------CYALFWYIFSLAHVALFVTRFSFSEELQSFVGALIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIVPSPKTICYLFNSISKWICSHTTTGRVKRQNSLKEWKSLRQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEMRDLL 797
BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: TRPC1 (transient receptor potential cation channel, subfamily C, member 1 [Source:NCBI gene;Acc:100497011]) HSP 1 Score: 278.1 bits (710), Expect = 9.725e-132 Identity = 186/441 (42.18%), Postives = 281/441 (63.72%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPS----TDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER FLLA E+ D +K+ L+ + NIN D LGRNAI I+IE E++++L+LLL Y DALL AI+ E AV+I++N Q + +P+ + N S T D+ P+ILA+HR+NYEI+ +LL + +PKPH + C C +C K+DSLRHS+ R++ Y+ LASP+LI L+ +DPIL AFELS +LK L +E EF+ +YE L+ KC+ FA+ LL Q R S EL ++LNH + S+ +++R L + L+RLKLAIKYNQK FV+ +CQQ L ++W+ + G+RR+ K+ ++ + +P+L+ YL+ P+S ++ PF+KFI H +SY FLLLL L +L YN + + G I+++LI+++ G +W +VK LW +G++ ++ + N L F NSLY+AT +L+ VA+ K
Sbjct: 46 ERLFLLACEKGDYYMVKKLLEENSSEELNINSVDVLGRNAITISIENENLDILQLLLNYGCQSTDALLVAIDSEVVGAVDILLNHQPKWR-TRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCTAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELAQKCKTFAKDLLAQARNSRELEVILNHQS---SDEPVDKRGL--LEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMAGYRRKHTCKKILIVLTVGIFWPVLSVCYLLAPKSQVGRIIHTPFMKFIIHGASYFTFLLLLNLYSLV--YNE-DKKNTMGPALERIDFLLIMWLIGMVWSDVKRLWYDGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNK 477 HSP 2 Score: 215.698 bits (548), Expect = 9.725e-132 Identity = 124/310 (40.00%), Postives = 184/310 (59.35%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGL--VDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWF-KMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLH-RQKAEDNEGVTEDDLNEIKGDISAFRFELLDIL 2604
R WD++ PTL++E LFA N+ S L+L +++T + LGPLQIS+G+ML D KF +++LVL +F GL QL Y K T ++ K+ + S + +++ T +L+W + L V L + + FVG L+ GTY+ + +IVL +L+AM++ S+QLIA D EWKFAR+KLW+SYF+D TLP PFNI+ SPKTI YLF K C + G+ R +S+K+ S + ++ YQKVM L+ RYL RQK + + T ++LNE++ D+S FR E+ D+L
Sbjct: 484 RKDWDAFHPTLVAEGLFAFGNVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQL---YDKGY--TTNEQKDCVGIFCEQQSNDAFHSFTGT-----------CYALFWYIFSLAHVALFVTRFSFSEELQSFVGALIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIVPSPKTICYLFNSISKWICSHTTTGRVKRQNSLKEWKSLRQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEMRDLL 777
BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc5 (transient receptor potential cation channel, subfamily C, member 5 [Source:MGI Symbol;Acc:MGI:109524]) HSP 1 Score: 378.252 bits (970), Expect = 0.000e+0 Identity = 231/438 (52.74%), Postives = 313/438 (71.46%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
E+ FL AVE+ D A++K+ L ++ NINC DPLGR+A+LIAIE E++E++ELLL + + +GDALL+AI +E AVE++++ + +++ T S FTPDITPI+LA+H +NYEIIKLL+ + IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEFKAEYE LS +C+ FA+ LL+Q R S EL I+LNH + + L+ + H LA+LK+AIKY+QK FVA P+CQQLLA+LWY+G PG+RR+ ++ K+ I +FPML+ YLI PRS +KKPFIKFICH++SY+ FL +L+LA+ I L +G PTV+EW+++ ++ GFIW E+KE+W+ G YI D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 EKAFLSAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDD--HSEELDPQK------YHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLH---VQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVK 459 HSP 2 Score: 303.138 bits (775), Expect = 0.000e+0 Identity = 155/315 (49.21%), Postives = 217/315 (68.89%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSK---GKKSRWHSIKKIVSKVNE---MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA +NI S+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + ++ ++ K C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+ YL WF N C + G++ R H+++ + + Q YQ+V+ NL+ RY+ + ++ NEG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 466 REEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIR---------------CEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFN-NTFCPKRDPDGRRRR-HNLRSFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDLLGN 763
BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc4 (transient receptor potential cation channel, subfamily C, member 4 [Source:MGI Symbol;Acc:MGI:109525]) HSP 1 Score: 377.481 bits (968), Expect = 0.000e+0 Identity = 232/446 (52.02%), Postives = 319/446 (71.52%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG---LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNEN 1672
E+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++EL+ELLL +++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+ALASPSLIALSS+DP LTAF+LSWEL+ L ++ENEFK+EYE LS +C+ FA+ LL+QTR S EL I+LN+ R+ +SLI+ LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ F I +FP+ + YLI P+S ++KPFIKFICH++SY+ FL LL+LA+ I+ + L + +G PT++EW+++ ++ GFIW E+K++W+ G++ YI D WNL+DF NSLY+ATISL+ VA+ K S N
Sbjct: 33 EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY------------RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDL---NRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALN 463 HSP 2 Score: 313.153 bits (801), Expect = 0.000e+0 Identity = 155/315 (49.21%), Postives = 219/315 (69.52%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK--SRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMT 2622
R WD + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + + +C + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYFE+G TLP PFN+I SPK+++YL W + LCK K ++ + +I + + +YQ+VM NL+ RY+ ++A+ EG+TE+++ E+K DIS+FRFE+L +L+ + ++
Sbjct: 465 RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIR------------------CEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTH-LCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLS 760
BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc4 (transient receptor potential cation channel, subfamily C, member 4 [Source:MGI Symbol;Acc:MGI:109525]) HSP 1 Score: 377.096 bits (967), Expect = 0.000e+0 Identity = 232/446 (52.02%), Postives = 319/446 (71.52%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG---LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNEN 1672
E+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++EL+ELLL +++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+ALASPSLIALSS+DP LTAF+LSWEL+ L ++ENEFK+EYE LS +C+ FA+ LL+QTR S EL I+LN+ R+ +SLI+ LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ F I +FP+ + YLI P+S ++KPFIKFICH++SY+ FL LL+LA+ I+ + L + +G PT++EW+++ ++ GFIW E+K++W+ G++ YI D WNL+DF NSLY+ATISL+ VA+ K S N
Sbjct: 33 EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY------------RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDL---NRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALN 463 HSP 2 Score: 311.997 bits (798), Expect = 0.000e+0 Identity = 155/315 (49.21%), Postives = 219/315 (69.52%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK--SRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMT 2622
R WD + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + + +C + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYFE+G TLP PFN+I SPK+++YL W + LCK K ++ + +I + + +YQ+VM NL+ RY+ ++A+ EG+TE+++ E+K DIS+FRFE+L +L+ + ++
Sbjct: 465 RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIR------------------CEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTH-LCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLS 760
BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc1 (transient receptor potential cation channel, subfamily C, member 1 [Source:MGI Symbol;Acc:MGI:109528]) HSP 1 Score: 286.189 bits (731), Expect = 8.285e-135 Identity = 187/441 (42.40%), Postives = 281/441 (63.72%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPS----TDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
E+ FLLA ++ D +K+ L+ + NINC D LGRNA+ I IE E +++L+LLL Y DALL AI+ E AV+I++N + + +P+ + N S T D+ P+ILA+HR+NYEI+ +LL + +PKPH + C C +C K+DSLRHS+ R++ Y+ LASP+LI L+ +DPIL AFELS +LK L +E EF+ +YE L+ +C+ FA+ LL Q R S EL ++LNH++ S+ L++R L + L+RLKLAIKYNQK FV+ +CQQ L ++W+ + G+RR+P K+ + + +P+L+ YLI P+S F ++ PF+KFI H +SY FLLLL L +L YN + + G I+++LI++I G IW ++K LW G++ ++ + N L F NSLY+AT +L+ VA+ K
Sbjct: 64 EKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENESLDILQLLLDYGCQSADALLVAIDSEVVGAVDILLNHRPK-RSSRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTS---SDEPLDKRGL--LEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSL--VYNE-DKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNK 495 HSP 2 Score: 217.238 bits (552), Expect = 8.285e-135 Identity = 125/313 (39.94%), Postives = 185/313 (59.11%), Query Frame = 1
Query: 1678 FMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNL--NLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWF-KMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLH-RQKAEDNEGVTEDDLNEIKGDISAFRFELLDIL 2604
F R WD++ PTL++E LFA AN+ S L+L +++T + LGPLQIS+G+ML D KF +++LVL +F GL QL Y K T + K+ + S + +++ T +L+W + L ++ Y + FVG ++ GTY+ + +IVL +L+AM++ S+QLIA D EWKFAR+KLW+SYF+D TLP PFNII SPKTI Y+ K C SKGK R +S+K+ + + ++ YQKVM L+ RYL RQK + + T ++LNE++ D+S FR E+ D+L
Sbjct: 499 FADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQL---YDKGY--TSKEQKDCVGIFCEQQSNDTFHSFIGT-----------CFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLL 795
BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc7 (transient receptor potential cation channel, subfamily C, member 7 [Source:MGI Symbol;Acc:MGI:1349470]) HSP 1 Score: 260.766 bits (665), Expect = 2.730e-132 Identity = 179/487 (36.76%), Postives = 273/487 (56.06%), Query Frame = 2
Query: 299 PDLMLDENRKNNYPNLERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPST----------DYTS--NLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTH--GLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSY-MXXXXXXXXXXXRIE-YNHLENDDYRGNTPTVI----------EWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENI 1675
P M +E + P ER FL + E +I +++ L+ S+ N NC D +G+NA+ +A+ E+ + L L + +GDALL AI++ VE I++ Q+ + D+ + + F+ DITPIILA+H YEI+ +LL +G RI +PHD C C+ C E Q++DS HS+SR+NAY+ LAS + ++LSS+DP+LTA ELS EL RL +E EFK +Y LS +C+DF +L+ R +EE+ +LN + N D H L+R+KLAIKY K FVAHP+CQQ L ++WYE L G R++ K +FG+S P LA Y I P S ++ PF+KF+ H+ S+ + LL++ A+ R E L N+ + + E +++ ++ G IW E KE+WE G + Y++ +WNLLDF S++VA+ + R +A+ K+S +
Sbjct: 29 PAYMFNEKGTSLTPEEER-FLDSAEYGNIPVVRKMLEESKT--LNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILSHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILN-----------GDVNLQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGQTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKASEAQL 501 HSP 2 Score: 234.187 bits (596), Expect = 2.730e-132 Identity = 132/333 (39.64%), Postives = 189/333 (56.76%), Query Frame = 1
Query: 1672 YYFMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNC---LCKSKGK----------------KSRWHSIKK-----IVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLD 2598
Y+ R KW DP +ISE L+A A + S ++ YI N + GPLQISLGR + DI KF +I+++V VAF G+ L +Y + YN FT++ E ++L+WS +GL ++ ++ L+Y H+F E +G +++G Y+ ++VLLNMLIAM+N SYQ I E AD+EWKFAR+KLW+SYF++G TLP PFN++ SPK+ YYL KM C LC+SK K K+R+ + + + RYQK+M LI RY+L Q +N+ V E +L EIK DIS+ R+ELL+
Sbjct: 523 YFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAK-----------------------YN------PAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKM-CLIELCQSKAKRCENDLEMGMLNSKFRKTRYQAGMRNSENLTANSTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 825
BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|Q9VJJ7|TRPG_DROME (Transient receptor potential-gamma protein OS=Drosophila melanogaster OX=7227 GN=Trpgamma PE=1 SV=2) HSP 1 Score: 412.149 bits (1058), Expect = 0.000e+0 Identity = 249/465 (53.55%), Postives = 330/465 (70.97%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGF-NINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQ-IEVHDQ-KPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG----LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIE--------------YNHLEN-DDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENI 1675
E++FLLAVER D+A +R L +Q T + N+NC DPLGR A+L+AI+ E++E++ELL+ Y++D DALLH+I+EE EAVE++++ + + H + S + S +S+FTPDITP+ILA+HRDNYEIIK+LLDRG +P PHD+RC CD CV+S+++DSLRHS+SRINAY+ALASPSLIALSSKDPILTAFELSWEL+RL LE+EFK EY+ L +C+DFA ALL+ TR S EL ILLNH + + HG L RLKLAIK QK FVAH + QQLLAS+WYEGLPGFRR+ + I I MFP+ + Y++ P S+ M+KPFIKFICHS+SY FL LL+LA+ RIE N +E RG PT IEW+++ +++G IW EVK+LW+ G++ Y+ DMWN++DF TNSLYVAT++LR V++++ E I
Sbjct: 21 EKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNH-------------DPTGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMI 472 HSP 2 Score: 352.443 bits (903), Expect = 0.000e+0 Identity = 169/316 (53.48%), Postives = 229/316 (72.47%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWF-KMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNV 2631
R +WD++DP LISE LF+AANIFS+LKLVYIF+VNP+LGPLQ+SL RM+ DIMKFF +Y+LVL AF GLNQLLW+YA + C + L N + + N C + F++LFE Q+L+W+ +GL+DL + L+ FT F G LMFGTYS I ++VLLN+LIAMMN SYQLI+E+AD+EWKFARSKLWISYFE+G T P PFNII +PK+I+Y W ++ C S ++ +I++ + ++ + +YQ++M NL+ RY+ Q+ +++GVTEDD+NEIK DISAFR EL++ILKN+GM NV
Sbjct: 482 RERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDP--NACIV-WRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVEILKNSGMDTNV 794
BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|O62852|TRPC5_RABIT (Short transient receptor potential channel 5 OS=Oryctolagus cuniculus OX=9986 GN=TRPC5 PE=2 SV=1) HSP 1 Score: 378.252 bits (970), Expect = 0.000e+0 Identity = 231/438 (52.74%), Postives = 313/438 (71.46%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
E+ FL AVE+ D A++K+ L ++ NINC DPLGR+A+LIAIE E++E++ELLL + + +GDALL+AI +E AVE++++ + +++ T S FTPDITPI+LA+H +NYEIIKLL+ + IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEFKAEYE LS +C+ FA+ LL+Q R S EL I+LNH + + L+ + H LA+LK+AIKY+QK FVA P+CQQLLA+LWY+G PG+RR+ ++ K+ I +FPML+ YLI PRS +KKPFIKFICH++SY+ FL +L+LA+ I L +G PTV+EW+++ ++ GFIW E+KE+W+ G YI D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 EKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDD--HSEELDPQK------YHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLH---VQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVK 459 HSP 2 Score: 303.138 bits (775), Expect = 0.000e+0 Identity = 155/315 (49.21%), Postives = 217/315 (68.89%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSK---GKKSRWHSIKKIVSKVNE---MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA +NI S+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + ++ ++ K C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+ YL WF N C + G++ R H+++ + + Q YQ+V+ NL+ RY+ + ++ NEG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 466 REEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIR---------------CEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFN-NTFCPKRDPDGRRRR-HNLRSFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDLLGN 763
BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|Q9QX29|TRPC5_MOUSE (Short transient receptor potential channel 5 OS=Mus musculus OX=10090 GN=Trpc5 PE=1 SV=2) HSP 1 Score: 378.252 bits (970), Expect = 0.000e+0 Identity = 231/438 (52.74%), Postives = 313/438 (71.46%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
E+ FL AVE+ D A++K+ L ++ NINC DPLGR+A+LIAIE E++E++ELLL + + +GDALL+AI +E AVE++++ + +++ T S FTPDITPI+LA+H +NYEIIKLL+ + IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEFKAEYE LS +C+ FA+ LL+Q R S EL I+LNH + + L+ + H LA+LK+AIKY+QK FVA P+CQQLLA+LWY+G PG+RR+ ++ K+ I +FPML+ YLI PRS +KKPFIKFICH++SY+ FL +L+LA+ I L +G PTV+EW+++ ++ GFIW E+KE+W+ G YI D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 EKAFLSAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDD--HSEELDPQK------YHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLH---VQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVK 459 HSP 2 Score: 303.138 bits (775), Expect = 0.000e+0 Identity = 155/315 (49.21%), Postives = 217/315 (68.89%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSK---GKKSRWHSIKKIVSKVNE---MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA +NI S+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + ++ ++ K C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+ YL WF N C + G++ R H+++ + + Q YQ+V+ NL+ RY+ + ++ NEG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 466 REEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIR---------------CEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFN-NTFCPKRDPDGRRRR-HNLRSFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDLLGN 763
BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|Q9UL62|TRPC5_HUMAN (Short transient receptor potential channel 5 OS=Homo sapiens OX=9606 GN=TRPC5 PE=1 SV=1) HSP 1 Score: 377.867 bits (969), Expect = 0.000e+0 Identity = 231/438 (52.74%), Postives = 313/438 (71.46%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
E+ FL AVE+ D A++K+ L ++ NINC DPLGR+A+LIAIE E++E++ELLL + + +GDALL+AI +E AVE++++ + +++ T S FTPDITPI+LA+H +NYEIIKLL+ + IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEFKAEYE LS +C+ FA+ LL+Q R S EL I+LNH + + L+ + H LA+LK+AIKY+QK FVA P+CQQLLA+LWY+G PG+RR+ ++ K+ I +FPML+ YLI PRS +KKPFIKFICH++SY+ FL +L+LA+ I L +G PTV+EW+++ ++ GFIW E+KE+W+ G YI D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 EKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDD--HSEELDPQK------YHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLH---VQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVK 459 HSP 2 Score: 293.508 bits (750), Expect = 0.000e+0 Identity = 152/314 (48.41%), Postives = 213/314 (67.83%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKS--RWHSIKKIVSKVNE---MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA +NI S+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + ++ ++ K C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+ YL WF N C + R +++ + + Q YQ+V+ NL+ RY+ + ++ +EG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 466 REEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIR---------------CEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFN-NTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGN 763
BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|Q9UBN4|TRPC4_HUMAN (Short transient receptor potential channel 4 OS=Homo sapiens OX=9606 GN=TRPC4 PE=1 SV=1) HSP 1 Score: 377.867 bits (969), Expect = 0.000e+0 Identity = 232/446 (52.02%), Postives = 319/446 (71.52%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG---LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNEN 1672
E+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++EL+ELLL +++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+ALASPSLIALSS+DP LTAF+LSWEL+ L ++ENEFK+EYE LS +C+ FA+ LL+QTR S EL I+LN+ R+ +SLI+ LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ F I +FP+ + YLI P+S ++KPFIKFICH++SY+ FL LL+LA+ I+ + L + +G PT++EW+++ ++ GFIW E+K++W+ G++ YI D WNL+DF NSLY+ATISL+ VA+ K S N
Sbjct: 33 EKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY------------RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDL---NRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALN 463 HSP 2 Score: 313.538 bits (802), Expect = 0.000e+0 Identity = 156/315 (49.52%), Postives = 217/315 (68.89%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK--SRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMT 2622
R WD + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y + + TC + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYFE+G TLP PFN+I SPK+++YL W + LCK K ++ + +I + + +YQ+VM NL+ RY+ + A+ EG+TE++ E+K DIS+FRFE+L +L+ + ++
Sbjct: 465 RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIR------------------CEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH-LCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLS 760
BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A267DGY4 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029366g2 PE=3 SV=1) HSP 1 Score: 481.871 bits (1239), Expect = 0.000e+0 Identity = 278/442 (62.90%), Postives = 348/442 (78.73%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKP-STDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIE---YNHLEND-DYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER++L AVE D+A+++R ++S+ G NINCRD LGR+A+ +AIEYEHIELLE+LL Y+L+LGDALLHAI EEN AVE+++++Q E +K S + SSSFTPD+TPIILA+ DNYEIIKLLLDRGDR+PKPH+LRCAC CV + K+DSL+HSKSRINAY+ALASPSLIALSSKDPILTAFELSWE+ RLGRLE+EF+ EYE LS C+ FA ALLEQTR SEELAI+LN G N LN++ + LARLK+AIKY QK FVAHPHCQQLLA+LWYEGLPGFRR+ +++GMI + +FP+L+ +YL+ PRS M+KPFIKFICHS+SYMLFL L+LAA+R+E + LE RG P+++EWI++IYI GF+WQE+K+LW G+K Y+ DMWNLLDF TN+LYVATI+LR V+YY+
Sbjct: 88 ERRYLQAVELGDLATVRRSIESASSLGININCRDSLGRSALHVAIEYEHIELLEVLLAYNLELGDALLHAIQEENIIAVEMLLSSQTERQKKKDLSGLLGTTPSSSFTPDVTPIILAAQIDNYEIIKLLLDRGDRVPKPHELRCACVDCVRAHKEDSLQHSKSRINAYKALASPSLIALSSKDPILTAFELSWEMHRLGRLEHEFREEYENLSADCQKFATALLEQTRSSEELAIVLNQDAGQ-GNAKLNDKTLTE-GERMNLARLKMAIKYKQKKFVAHPHCQQLLAALWYEGLPGFRRKHMFFQMGMIGTFAGIFPLLSMVYLVAPRSELGQKMRKPFIKFICHSASYMLFLGFLVLAAIRVEDLIMDTLEEKMQERGGAPSIVEWIIVIYILGFVWQEIKQLWGEGIKAYVTDMWNLLDFITNALYVATITLRGVSYYR 527 HSP 2 Score: 434.876 bits (1117), Expect = 0.000e+0 Identity = 202/314 (64.33%), Postives = 244/314 (77.71%), Query Frame = 1
Query: 1681 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMN-CLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGM 2619
+ R WD+YDPTLISECLFA ANIFS LKLV IFT+NP+LGPLQISLGRMLNDI+KF + +LV+ +FACG NQL WFYA +R + C D NK++ ++ Y+YC TRG+ F++LFEI QSLYWS YGL+DLSN +LEY H FTEF+GKLM+G +S IT IVLLNMLIAMMN S++ I QAD EWKFAR KLWISYF++G TLP PFNII SPK+ Y W K C C + ++S+W SI+K+V KVNE E RYQ VM +LI RYL+ RQK++D +GVTEDDLNEIKGDISAFRFELL+I + NGM
Sbjct: 537 LHRKYWDAYDPTLISECLFAIANIFSMLKLVNIFTINPHLGPLQISLGRMLNDILKFLFVVVLVICSFACGFNQLYWFYAYQRNKYCQD--NKFYFGITGTDLDK-YSYCVTRGRTFSNLFEITQSLYWSAYGLIDLSNTDLEYEHSFTEFIGKLMYGAFSAITFIVLLNMLIAMMNCSFEEIVAQADTEWKFARGKLWISYFDEGGTLPTPFNIIPSPKSFLYAMAWLKDKVCSCSKRHQRSKWQSIRKVVKKVNEKEARYQSVMRDLIKRYLMVRQKSDDKQGVTEDDLNEIKGDISAFRFELLEIFRTNGM 847
BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A267FS73 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029366g3 PE=3 SV=1) HSP 1 Score: 481.1 bits (1237), Expect = 0.000e+0 Identity = 277/442 (62.67%), Postives = 348/442 (78.73%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKP-STDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIE---YNHLEND-DYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER++L AVE D+A+++R ++S+ G NINCRD LGR+A+ +AIEYEHIELLE+LL Y+L+LGDALLHAI EEN AVE+++++Q E +K S + SSSFTPD+TPIILA+ DNYEIIKLLLDRGDR+PKPH+LRCAC CV + K+DSL+HSKSRINAY+ALASPSLIALSSKDPILTAFELSWE+ RLGRLE+EF+ EYE LS C+ FA ALLEQTR SEELAI+LN G N LN++ + LARLK+AIKY QK FVAHPHCQQLLA+LWYEGLPGFRR+ +++GMI + +FP+L+ +Y++ PRS M+KPFIKFICHS+SYMLFL L+LAA+R+E + LE RG P+++EWI++IYI GF+WQE+K+LW G+K Y+ DMWNLLDF TN+LYVATI+LR V+YY+
Sbjct: 88 ERRYLQAVELGDLATVRRSIESASSLGININCRDSLGRSALHVAIEYEHIELLEVLLAYNLELGDALLHAIQEENIIAVEMLLSSQTERQKKKDLSGLLGTTPSSSFTPDVTPIILAAQIDNYEIIKLLLDRGDRVPKPHELRCACVDCVRAHKEDSLQHSKSRINAYKALASPSLIALSSKDPILTAFELSWEMHRLGRLEHEFREEYENLSADCQKFATALLEQTRSSEELAIVLNQDAGQ-GNAKLNDKTLTE-GERMNLARLKMAIKYKQKKFVAHPHCQQLLAALWYEGLPGFRRKHMFFQMGMIGTFAGIFPLLSMVYMVAPRSELGQKMRKPFIKFICHSASYMLFLGFLVLAAIRVEDLIMDTLEEKMQERGGAPSIVEWIIVIYILGFVWQEIKQLWGEGIKAYVTDMWNLLDFITNALYVATITLRGVSYYR 527 HSP 2 Score: 434.876 bits (1117), Expect = 0.000e+0 Identity = 202/314 (64.33%), Postives = 244/314 (77.71%), Query Frame = 1
Query: 1681 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMN-CLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGM 2619
+ R WD+YDPTLISECLFA ANIFS LKLV IFT+NP+LGPLQISLGRMLNDI+KF + +LV+ +FACG NQL WFYA +R + C D NK++ ++ Y+YC TRG+ F++LFEI QSLYWS YGL+DLSN +LEY H FTEF+GKLM+G +S IT IVLLNMLIAMMN S++ I QAD EWKFAR KLWISYF++G TLP PFNII SPK+ Y W K C C + ++S+W SI+K+V KVNE E RYQ VM +LI RYL+ RQK++D +GVTEDDLNEIKGDISAFRFELL+I + NGM
Sbjct: 537 LHRKYWDAYDPTLISECLFAIANIFSMLKLVNIFTINPHLGPLQISLGRMLNDILKFLFVVVLVICSFACGFNQLYWFYAYQRNKYCQD--NKFYFGITGTDLDK-YSYCVTRGRTFSNLFEITQSLYWSAYGLIDLSNTDLEYEHSFTEFIGKLMYGAFSAITFIVLLNMLIAMMNCSFEEIVAQADTEWKFARGKLWISYFDEGGTLPTPFNIIPSPKSFLYAMAWLKDKVCSCSKRHQRSKWQSIRKVVKKVNEKEARYQSVMRDLIKRYLMVRQKSDDKQGVTEDDLNEIKGDISAFRFELLEIFRTNGM 847
BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A267DTY7 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029366g1 PE=3 SV=1) HSP 1 Score: 481.1 bits (1237), Expect = 0.000e+0 Identity = 277/442 (62.67%), Postives = 348/442 (78.73%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKP-STDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIE---YNHLEND-DYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER++L AVE D+A+++R ++S+ G NINCRD LGR+A+ +AIEYEHIELLE+LL Y+L+LGDALLHAI EEN AVE+++++Q E +K S + SSSFTPD+TPIILA+ DNYEIIKLLLDRGDR+PKPH+LRCAC CV + K+DSL+HSKSRINAY+ALASPSLIALSSKDPILTAFELSWE+ RLGRLE+EF+ EYE LS C+ FA ALLEQTR SEELAI+LN G N LN++ + L+RLK+AIKY QK FVAHPHCQQLLA+LWYEGLPGFRR+ +++GMI + +FP+L+ +YL+ PRS M+KPFIKFICHS+SYMLFL L+LAA+R+E + LE RG P+++EWI++IYI GF+WQE+K+LW G+K Y+ DMWNLLDF TN+LYVATI+LR V+YY+
Sbjct: 88 ERRYLQAVELGDLATVRRSIESASSLGININCRDSLGRSALHVAIEYEHIELLEVLLAYNLELGDALLHAIQEENIIAVEMLLSSQTERQKKKDLSGLLGTTPSSSFTPDVTPIILAAQIDNYEIIKLLLDRGDRVPKPHELRCACVDCVRAHKEDSLQHSKSRINAYKALASPSLIALSSKDPILTAFELSWEMHRLGRLEHEFREEYENLSADCQKFATALLEQTRSSEELAIVLNQDAGQ-GNAKLNDKTLTE-GERMNLSRLKMAIKYKQKKFVAHPHCQQLLAALWYEGLPGFRRKHMFFQMGMIGTFAGIFPLLSMVYLVAPRSELGQKMRKPFIKFICHSASYMLFLGFLVLAAIRVEDLIMDTLEEKMQERGGAPSIVEWIIVIYILGFVWQEIKQLWGEGIKAYVTDMWNLLDFITNALYVATITLRGVSYYR 527 HSP 2 Score: 293.893 bits (751), Expect = 0.000e+0 Identity = 137/209 (65.55%), Postives = 165/209 (78.95%), Query Frame = 1
Query: 1681 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTL 2307
+ R WD+YDPTLISECLFA ANIFS LKLV IFT+NP+LGPLQISLGRMLNDI+KF + +LV+ +FACG NQL WFYA +R + C D NK++ ++ Y+YC TRG+ F++LFEI QSLYWS YGL+DLSN +LEY H FTEF+GKLM+G +S IT IVLLNMLIAMMN S++ I QAD EWKFAR KLWISYF++G TL
Sbjct: 537 LHRKYWDAYDPTLISECLFAIANIFSMLKLVNIFTINPHLGPLQISLGRMLNDILKFLFVVVLVICSFACGFNQLYWFYAYQRNKYCQD--NKFYFGITGTDLDK-YSYCVTRGRTFSNLFEITQSLYWSAYGLIDLSNTDLEYEHSFTEFIGKLMYGAFSAITFIVLLNMLIAMMNCSFEEIVAQADTEWKFARGKLWISYFDEGGTL 742
BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A267DBT5 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003128g1 PE=3 SV=1) HSP 1 Score: 480.715 bits (1236), Expect = 0.000e+0 Identity = 277/442 (62.67%), Postives = 348/442 (78.73%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKP-STDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIE---YNHLEND-DYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER++L AVE D+A+++R ++S+ G NINCRD LGR+A+ +AIEYEHIELLE+LL Y+L+LGDALLHAI EEN AVE+++++Q E +K S + SSSFTPD+TPIILA+ DNYEIIKLLLDRGDR+PKPH+LRCAC CV + K+DSL+HSKSRINAY+ALASPSLIALSSKDPILTAFELSWE+ RLGRLE+EF+ EYE LS C+ FA ALLEQTR SEELAI+LN G N LN++ + L+RLK+AIKY QK FVAHPHCQQLLA+LWYEGLPGFRR+ +++GMI + +FP+L+ +YL+ PRS M+KPFIKFICHS+SYMLFL L+LAA+R+E + LE RG P+++EWI++IYI GF+WQE+K+LW G+K Y+ DMWNLLDF TN+LYVATI+LR V+YY+
Sbjct: 88 ERRYLQAVELGDLATVRRSIESASSLGININCRDSLGRSALHVAIEYEHIELLEVLLAYNLELGDALLHAIQEENIIAVEMLLSSQTERQKKKDLSGLLGTTPSSSFTPDVTPIILAAQIDNYEIIKLLLDRGDRVPKPHELRCACVDCVRAHKEDSLQHSKSRINAYKALASPSLIALSSKDPILTAFELSWEMHRLGRLEHEFREEYENLSADCQKFATALLEQTRSSEELAIVLNQDAGQ-GNAKLNDKTLTE-GERMNLSRLKMAIKYKQKKFVAHPHCQQLLAALWYEGLPGFRRKHMFFQMGMIGTFAGIFPLLSMVYLVAPRSELGQKMRKPFIKFICHSASYMLFLGFLVLAAIRVEDLIMDTLEEKMQERGGAPSIVEWIIVIYILGFVWQEIKQLWGEGIKAYVTDMWNLLDFITNALYVATITLRGVSYYR 527 HSP 2 Score: 381.333 bits (978), Expect = 0.000e+0 Identity = 178/284 (62.68%), Postives = 217/284 (76.41%), Query Frame = 1
Query: 1681 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMN-CLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNE 2529
+ R WD+YDPTLISECLFA ANIFS LKLV IFT+NP+LGPLQISLGRMLNDI+KF + +LV+ +FACG NQL WFYA +R + C D NK++ ++ Y+YC TRG+ F++LFEI QSLYWS YGL+DLSN +LEY H FTEF+GKLM+G +S IT IVLLNMLIAMMN S++ I QAD EWKFAR KLWISYF++G TLP PFNII SPK+ Y W K C C + ++S+W SI+K+V KVNE E RYQ VM +LI RYL+ RQK++DNE
Sbjct: 537 LHRKYWDAYDPTLISECLFAIANIFSMLKLVNIFTINPHLGPLQISLGRMLNDILKFLFVVVLVICSFACGFNQLYWFYAYQRNKYCQD--NKFYFGITGTDLDK-YSYCVTRGRTFSNLFEITQSLYWSAYGLIDLSNTDLEYEHSFTEFIGKLMYGAFSAITFIVLLNMLIAMMNCSFEEIVAQADTEWKFARGKLWISYFDEGGTLPTPFNIIPSPKSFLYAMAWLKDKVCSCSKRHQRSKWQSIRKVVKKVNEKEARYQSVMRDLIKRYLMVRQKSDDNE 817
BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A267F969 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013797g1 PE=3 SV=1) HSP 1 Score: 469.929 bits (1208), Expect = 0.000e+0 Identity = 266/445 (59.78%), Postives = 343/445 (77.08%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTD--YTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTH-GLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIE---YNHLE-NDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER++LL+VE D+ S+++++++++ N+NC D LGR+A+LIAIE+E L LL L+LGDALLHAI EEN AVE++++AQ E +KP + SSSFTPDITPIILA+H DNYEI+K+LLDRGDR+PKPH+LRCACD CV +QK+DSLRHSKSRINAY+ALASPSLI LSSKDPILTAFELSWE+KRLGRLENEFK+EYE L+ KC+++A ALLEQTR S ELAI+LN G S +NE+ + + L+RLKLAIKY QK FVAHPHCQQLLA+LWY+GLPGFRR+ + ++GMI + +FP LA +YL+ P S M+KPFIKFICHS+SY+LFL L+LAA+R+E ++ +E RG P+ +E I++ Y+ GF+WQE+K+LW G K Y+ DMWNLLDFATN+LY+ATI+LR VA+Y+
Sbjct: 73 ERRYLLSVEMGDMTSVRQYVENAETLSVNVNCVDSLGRSAVLIAIEFEHIELLEMLLSFGFLELGDALLHAIQEENVVAVEMLLHAQAEKQQKKPQAPGPMGAVPSSSFTPDITPIILAAHIDNYEILKILLDRGDRVPKPHELRCACDECVLAQKEDSLRHSKSRINAYKALASPSLICLSSKDPILTAFELSWEMKRLGRLENEFKSEYEQLAAKCQEYASALLEQTRSSAELAIVLNQDIGQ-SGHKVNEKALEETDEERMTLSRLKLAIKYKQKKFVAHPHCQQLLAALWYDGLPGFRRKHLILQMGMIATFAGIFPALAFMYLLAPHSEMGQKMRKPFIKFICHSASYLLFLGFLVLAAIRVEDLLFDTMELKMKERGAGPSAVELIIVTYVMGFVWQEIKQLWNEGAKAYVTDMWNLLDFATNALYIATITLRGVAWYR 516 HSP 2 Score: 441.425 bits (1134), Expect = 0.000e+0 Identity = 206/312 (66.03%), Postives = 248/312 (79.49%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMN-CLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGM 2619
R WD+YDPTLISECLFA ANIFS LKLVYIFTVNP+LGPLQISLGRML+DI+KF + +LVL +FACG NQL WFYA +R + C D K + + ++ E Y YC TRG+ F++LFEI Q+LYWSTYGL+DLSN +LEY H FTEFVGKLM+G +S IT +VLLNMLIAMMN SY+ IA QAD EWKFARSKLWISYFE+G TLPVPFNII SPK+ Y+ W K C C + ++S+W SI+K+V +VNE E RYQ VM +L+ RYL+ RQ+ ++ +GVTEDDLNEIKGDISAFRFELL+IL+ NGM
Sbjct: 528 RQYWDAYDPTLISECLFATANIFSMLKLVYIFTVNPHLGPLQISLGRMLSDILKFLFVVVLVLSSFACGFNQLYWFYAYERNKYCKDVKLGFGITGSDL---EKYQYCVTRGRTFSNLFEITQTLYWSTYGLIDLSNTDLEYEHSFTEFVGKLMYGVFSAITFVVLLNMLIAMMNCSYESIATQADTEWKFARSKLWISYFEEGGTLPVPFNIIPSPKSFLYIATWTKERLCSCSKQHQRSKWQSIRKVVKRVNEREARYQTVMRDLVKRYLMVRQRLDERQGVTEDDLNEIKGDISAFRFELLEILRTNGM 836
BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc5a (short transient receptor potential channel 5-like [Source:NCBI gene;Acc:103044006]) HSP 1 Score: 373.244 bits (957), Expect = 0.000e+0 Identity = 227/438 (51.83%), Postives = 311/438 (71.00%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKT-GFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER FLLAVE+ D A +K L ++ ++NC DPLGR+A+LIAIE E++E++ELLL + ++ GDALL+AI +E AVE++++ + +++ + S FTPDITPI+LA+H +NYEIIKLL+ IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEF+ EYE LS +C+ FA+ LL+Q R S EL +LNH + + L+ R + LA+LKLAIKY+QK FV+ P+CQQLLA+LWY+G PG+RRR + K+ M I +FP+ + IYL+ PRS+ +KKPFIKFICH++SY+ FL LL+LA+ I +L +G PTV+EW+++ ++ GFIW E+KE+W+ G Y+ D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 36 ERAFLLAVEKGDYAGVKHALQEAEVYYNIDVNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHRRPSGEKQVPSLMMDAQFSEFTPDITPIMLAAHTNNYEIIKLLVQHKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKRFAKDLLDQARSSRELETILNHRDD--QSEELDPR------ECRDLAKLKLAIKYHQKEFVSQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCIIIGLLFPVFSIIYLLAPRSSLGFFIKKPFIKFICHTASYLTFLFLLLLASQHIARTNLH---MQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFTEYVHDWWNLMDFAMNSLYLATISLKMVAYVK 462 HSP 2 Score: 298.901 bits (764), Expect = 0.000e+0 Identity = 153/313 (48.88%), Postives = 214/313 (68.37%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWH-SIKKIVSKVNE---MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y ET + D+ + C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNI+ SPK+ +YL W + S H ++K + K + + YQ+V+ +L+ RY+ + A+ NEG+TE++ E+K DIS+FR+E++D+L N
Sbjct: 469 REEWEMWHPTLMAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYY-----ETQAADEPNHCKGIR----------CEKQNNAFSTLFETLQSLFWSIFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIVPSPKSAWYLCCWLHRWLCWRGDAPHSEKHENLKDLTEKHADRIIQNKHYQEVIRSLVKRYVAAMIRSAKTNEGLTEENFKELKQDISSFRYEVMDLLGN 766
BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc4b (short transient receptor potential channel 4-like [Source:NCBI gene;Acc:103045092]) HSP 1 Score: 367.851 bits (943), Expect = 0.000e+0 Identity = 230/441 (52.15%), Postives = 307/441 (69.61%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSN 1666
E+ +L AVER D S+KR LD ++ NINC DPLGR A+LIAIE E++EL+ELLL Y++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+AL+SPSLIALSS+DP LTAF+LSWEL+ L ++ENEFK EYE LS +C+ FA+ LL+QTR S EL ++LN + S E N + LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K I +FP L+ YL+ P+S + ++KPFIKFICH++SY+ FL LL+LA+ I + +G PT +EW+++ ++ GFIW E+K++W+ G + YI D WNL+DF NSLY+ATISL+ VAY K S
Sbjct: 33 EKAYLSAVERGDYGSVKRALDEAEIYFKININCVDPLGRTALLIAIENENLELIELLLSYNVHVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKLLVQKGVSVPQPHEVRCNCMECVSSSDVDSLRHSRSRLNIYRALSSPSLIALSSEDPFLTAFQLSWELQELSKVENEFKTEYEELSHQCKRFAKDLLDQTRSSRELELILNFRD-DLSLLQDQESNNE-------LARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKFITCVFIGLLFPTLSICYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIVST---KPNLQGPAPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSG 462 HSP 2 Score: 310.071 bits (793), Expect = 0.000e+0 Identity = 151/310 (48.71%), Postives = 211/310 (68.06%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNN 2613
R KW+ + PTL++E +FA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y K C + C + F++LFE +QSL+WS +GL+ L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQ IA+ ADIEWKFAR+KLW+SYFE+G TLP PFNII SPK+I+YL W K++ + + + + + ++ + +YQ+V+ NL+ RY+ + A+ EG+TE++ E+K DIS+FR+E+L ++K N
Sbjct: 466 RDKWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYDTKDDRVCKGIR------------------CEHQNNAFSTLFETLQSLFWSIFGLIGLYVTNVQADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPTPFNIIPSPKSIWYLITWIKIHVFRRKSKRTETFGVLGRRAAEKVRLNNQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVLGMMKGN 757
BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc4a (short transient receptor potential channel 4-like [Source:NCBI gene;Acc:103035222]) HSP 1 Score: 361.303 bits (926), Expect = 0.000e+0 Identity = 222/444 (50.00%), Postives = 311/444 (70.05%), Query Frame = 2
Query: 344 LERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNEN 1672
LE+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++E++ELLL +++ +GDALLHAI +E AVE+++N + + + S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+AL+SPSLIALSS+DP LTAF LSWEL+ L ++ENEFK EYE LS +C+ FA+ LL+QTR S EL ++LN+ + +N + + D LARLKLA++Y+QK FVA P+CQQLLAS WY+ PG+RRR + K I +FP+ + YL+ P+S + ++KPFIKFICH++SY+ FL LL+LA+ I + + +G P +EW+++ ++ GFIW E+K++W+ G + Y+ D WNL+DF NSLY+ATISL+ VAY K S N
Sbjct: 32 LEKAYLNAVEKGDYASVKQSLEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKQRGGMQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKLLVQKGVSMPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYRALSSPSLIALSSEDPFLTAFRLSWELEELSKVENEFKYEYEELSQQCKQFAKNLLDQTRSSRELELILNYRDD------INPLEDEGVND---LARLKLAVRYHQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKFITCIFIGLLFPLFSIFYLVAPKSHYGLFIRKPFIKFICHTASYLTFLFLLLLASQHITGSKALS---QGPPPNTVEWMILPWVLGFIWAEIKQMWDGGFQDYVHDWWNLMDFVMNSLYLATISLKVVAYLKYSGSN 463 HSP 2 Score: 310.071 bits (793), Expect = 0.000e+0 Identity = 154/311 (49.52%), Postives = 212/311 (68.17%), Query Frame = 1
Query: 1684 GRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNN 2613
R WD + PTL++E +FA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y ET + + K+ C + FT+LFE +QSL+WS +GL+DL N+ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQ IA+ ADIEWKFAR+KLW+SYFE+G TLP PFNII SPK+++Y W K N + K + +I + ++ + +YQ+V+ NL+ RY+ + A+ EG+TE++ E+K DIS+FR+E++ ++K N
Sbjct: 464 ARESWDMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYY-----ETDASNSTKWCKGIR----------CEHQNNAFTTLFETLQSLFWSIFGLIDLHVTNVGPDHRFTEFVGATMFGTYNIISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSVWYFVRWIKRNVFRVAATKTETFGTISRRAAENVRINHQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVMGMMKGN 759
BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc5b (transient receptor potential cation channel, subfamily C, member 5b [Source:ZFIN;Acc:ZDB-GENE-091112-24]) HSP 1 Score: 372.859 bits (956), Expect = 9.386e-156 Identity = 226/438 (51.60%), Postives = 309/438 (70.55%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER +L AVE+ D A +K L ++ NINC DPLGR+A+LIAIE E++E++ELLL + + +GDALL+AI +E AVE++++ + +++ + S FTPDITPI+LA+H +NYEIIKLL+ R IP+PH +RC C CV S + DSLRHS+SR+N Y+ LASPSLIALSS+DPILTAF L WELK L ++ENEF+ EYE LS +C+ FA+ LL+Q R S EL +LNH + + L+ R + LA+LKLAIKY+QK FVA P+CQQLLA+LWY+G PG+RRR ++ K+ F I +FP+ + IYL+ P+S +KKPFIKFICH++SY+ FL LL+LA+ I L +G PT++EW+++ ++ GFIW E+KE+W+ G Y+ D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 ERAYLTAVEKGDYAGVKMALQEAEIYYNININCLDPLGRSALLIAIENENLEVMELLLSHGVQVGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPALMMDSQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKTLASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRDD--HSEELDPR------ECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWVVKLVTCFTIGLLFPVFSIIYLLAPKSALGFFIKKPFIKFICHTASYLTFLFLLLLASQHIVRTDLH---VQGPPPTIVEWMILPWVLGFIWAEIKEMWDGGFTEYVHDWWNLMDFAMNSLYLATISLKMVAYLK 459 HSP 2 Score: 199.904 bits (507), Expect = 9.386e-156 Identity = 119/312 (38.14%), Postives = 178/312 (57.05%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNL--NLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNN 2613
R +W+ + PTLI+E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y ET + D+ + QN + S F I+ L + + L L + +L+ P +++ + + IAM Q + ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+++YL W + + ++ H + + + +V+ NL+ RY+ ++ + +EG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 466 REEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYY-----ETEAADEPNHCKGIRCEKQNNAF-----------STFIIITFL--TVFALTALEDTFKDLKIP-----------------LSIAMFITRFIAMFPLPPQ---DHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSVWYLCVWLHSRLCGRGQPRQEEEHKHENLKEFTVKTVLLRNEVIRNLVKRYVAAMIRRTKTDEGLTEENFKELKQDISSFRYEVLDLLGNR 739
BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc7a (short transient receptor potential channel 7-like [Source:NCBI gene;Acc:103035292]) HSP 1 Score: 269.24 bits (687), Expect = 2.144e-133 Identity = 188/486 (38.68%), Postives = 281/486 (57.82%), Query Frame = 2
Query: 299 PDLMLDENRKNNYPNLERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIII-NAQIE-----VH---DQKPSTD----YTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXR--IEYNHLENDD--------YRGNTPTV--IEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENI 1675
P M E R + E +FL A E +I +++ L+ S+ N+NC D +G+NA+ +A+ E+ + L L + +GDALL AI++ VE I+ + E H +Q+P D Y + + F+ D+TP+ILA+H YEI+ +LL +G RI KPHD C C C+ESQKQDS HS+SR+NAY+ LAS + ++LSS+DP+LTA ELS EL +L +E EFK +Y LS +C+DF +L+ R +EE+ +L NG + T E N L+R+KLAIKY K FVAHP+CQQ L +LWYE L G R++P K + G+ P LA Y I P S +++ PF+KF+ H+ S+ FL LL+L A + +L N+ +R T E +++ ++ G IW E KE+WE+G + YIM +WN+LDF S+++A+ + R +A+ ++SN +
Sbjct: 83 PAYMFSE-RGTSLTAEEERFLDAAEYGNIPVVRKMLEESKT--LNVNCMDYMGQNALQLAVGNEHLEVTELLLKTEGLARIGDALLLAISKGYVRIVEAILAHPAFEGGLRFAHSPLEQEPREDDFYAYDED-GTRFSQDVTPVILAAHCQEYEIVHILLLKGARIEKPHDHFCKCSECMESQKQDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELSQLANIETEFKNDYRKLSMQCKDFVVGVLDLCRNTEEVEAIL---NGDVDHNTPREHNRPC------LSRVKLAIKYEVKKFVAHPNCQQQLLTLWYENLSGLRQQPIGVKCLTVLGVMVGLPFLAIAYWIMPYSKVGQVLRSPFMKFVAHAVSFTTFLGLLVLNASDRFLGVKNLPNETITDHPRQVFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEDGPREYIMHLWNILDFGMLSIFIASYTARLMAFLRASNAQL 555 HSP 2 Score: 229.18 bits (583), Expect = 2.144e-133 Identity = 129/333 (38.74%), Postives = 194/333 (58.26%), Query Frame = 1
Query: 1672 YYFMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCL---CKSKGKK-----------SR--------WHSIKKIVSKVNEMEQ--RYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLD 2598
Y+ R +W DP LISE L++ A + S ++ YI N + GPLQISLGR + DI KF +I+++V +AF G+ L +Y + YN FT++ E ++L+WS +GL ++ ++ L+Y H+F E +G +++G Y+ +IVLLNMLIAM+N SYQ I E AD+EWKFAR+KLW+SYF++G TLP PFN++ SPK+ YY+ + CL CK++G++ SR +H+ ++ K N ++ RYQK+M LI RY+L Q +N+ + E +L EIK DIS+ R+ELL+
Sbjct: 577 YFTYARNRWLPSDPQLISEGLYSIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFLAFMIGMFNLYSYYLGAK-----------------------YN------PAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINHSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPPPFNLVPSPKSFYYMALRTRA-CLVRQCKARGRRHGSQRDMDIPGSRTKLHRFRSYHAQEEYTVK-NPIKHPTRYQKLMKRLIKRYVLKAQTDSENDEINEGELKEIKQDISSLRYELLE 878
BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: trpc4b (transient receptor potential cation channel, subfamily C, member 4b [Source:ZFIN;Acc:ZDB-GENE-120329-1]) HSP 1 Score: 334.339 bits (856), Expect = 1.626e-135 Identity = 178/344 (51.74%), Postives = 239/344 (69.48%), Query Frame = 2
Query: 635 DYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSN 1666
++ SS FTPD+TPIILA+H +NYE+IKLLL RG +P+PH +RCAC C + D LRHS+SR+ Y+ALASP L+AL+S+DP LTAF LS EL L R+ENEFKAEYE LS +C+ FA+ LL+QTR + EL I+LN+ S A D L RLKLAIKY+QK FVA P+CQQLLASLWY+G PG+RRR + K+ + +FP+ + YL+ PRS A ++KPFIKFICH++SY+ FL LL+LA+ +I + + +G +PT++EW+++ +I IW E+K++W+ G Y+ D WNL+DF NSLY+ATISL+ VAY K S
Sbjct: 5 EFAEGHSSEFTPDMTPIILAAHTNNYELIKLLLTRGVSVPRPHAVRCACLQCAAGSEADGLRHSRSRLAVYRALASPCLVALASEDPFLTAFTLSCELCELSRVENEFKAEYEELSQQCKQFAKELLDQTRSTRELEIVLNYKEES--------DGAPEAPDAFNLERLKLAIKYHQKEFVAQPNCQQLLASLWYDGFPGWRRRHWAVKLVTCATLGLLFPLFSVCYLLAPRSRMAFFLRKPFIKFICHTASYLTFLFLLLLASQQIART---DPNMQGPSPTLVEWMILPWICRLIWAEIKQMWDGGFSEYVHDWWNLMDFVMNSLYLATISLKLVAYLKYSG 337 HSP 2 Score: 168.703 bits (426), Expect = 1.626e-135 Identity = 96/238 (40.34%), Postives = 142/238 (59.66%), Query Frame = 1
Query: 1684 GRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFY---AKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNT-SYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLC 2385
R +W+ + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y A + +TC + C + F++L ++ L+ S V L H FT + F + ++++ V L +++ + +++ + ADIEWKFAR+KLW+SYFE+G TLP PFNI+ SPK+ +YL + + C+C
Sbjct: 340 AREQWEMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETSAGQGNDTCKGIR------------------CEKQNNAFSTLCNCLKHLFPSVSICVHLCPSGSICFHLFTSV--SICFHLFPYVSICVHLFPSVSITSCNAFKNTVDHADIEWKFARTKLWMSYFEEGATLPPPFNIVPSPKSAWYLCRYVRA-CIC 556
BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: trpc4b (transient receptor potential cation channel, subfamily C, member 4b [Source:ZFIN;Acc:ZDB-GENE-120329-1]) HSP 1 Score: 328.946 bits (842), Expect = 2.808e-131 Identity = 175/334 (52.40%), Postives = 234/334 (70.06%), Query Frame = 2
Query: 665 TPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSN 1666
TPD+TPIILA+H +NYE+IKLLL RG +P+PH +RCAC C + D LRHS+SR+ Y+ALASP L+AL+S+DP LTAF LS EL L R+ENEFKAEYE LS +C+ FA+ LL+QTR + EL I+LN+ S A D L RLKLAIKY+QK FVA P+CQQLLASLWY+G PG+RRR + K+ + +FP+ + YL+ PRS A ++KPFIKFICH++SY+ FL LL+LA+ +I + + +G +PT++EW+++ +I IW E+K++W+ G Y+ D WNL+DF NSLY+ATISL+ VAY K S
Sbjct: 1 TPDMTPIILAAHTNNYELIKLLLTRGVSVPRPHAVRCACLQCAAGSEADGLRHSRSRLAVYRALASPCLVALASEDPFLTAFTLSCELCELSRVENEFKAEYEELSQQCKQFAKELLDQTRSTRELEIVLNYKEES--------DGAPEAPDAFNLERLKLAIKYHQKEFVAQPNCQQLLASLWYDGFPGWRRRHWAVKLVTCATLGLLFPLFSVCYLLAPRSRMAFFLRKPFIKFICHTASYLTFLFLLLLASQQIART---DPNMQGPSPTLVEWMILPWICRLIWAEIKQMWDGGFSEYVHDWWNLMDFVMNSLYLATISLKLVAYLKYSG 323 HSP 2 Score: 160.229 bits (404), Expect = 2.808e-131 Identity = 94/238 (39.50%), Postives = 139/238 (58.40%), Query Frame = 1
Query: 1684 GRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTY----SFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLC 2385
R +W+ + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y ET + N QN ++ +FTS+ + + + ++++ + +T+ ++ Y F + IV +I + + + ADIEWKFAR+KLW+SYFE+G TLP PFNI+ SPK+ +YL + + C+C
Sbjct: 326 AREQWEMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYY-----ETSAGQGNDTCKGIRCEKQNNAFS------TWFTSVSICFHLFPYVSICVHLFPSVSIFF---YTDKRKNMLNAAYLREMHFSSAIVACQTIIRASASDPNHVEDHADIEWKFARTKLWMSYFEEGATLPPPFNIVPSPKSAWYLCRYVRA-CIC 548
BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: trpc3 (transient receptor potential cation channel, subfamily C, member 3 [Source:ZFIN;Acc:ZDB-GENE-140129-1]) HSP 1 Score: 214.157 bits (544), Expect = 7.848e-107 Identity = 118/334 (35.33%), Postives = 191/334 (57.19%), Query Frame = 1
Query: 1669 KYYFMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFF-----------WFK--------MNCL-CKSK----GKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLD 2598
+Y+ + R W DP +ISE L++ A + S ++ YI N + GPLQISLG+ + DI KF +I+++V +AF G+ L +Y +V + F ++ E ++L+WS +GL +++++ + Y H+F E +G +++G Y+ ++VLLNMLIAM+N+SYQ I + +D+EWKFAR+KLWISYFE G TLPVPFN++ SPK+ L W K M+ L K+K +++ ++ + ++ + + RYQ++M LI RY+L Q ++N+ V E +L +IK DIS+ R+ELL+
Sbjct: 467 RYFNLARSHWLPSDPQIISEGLYSIAIVLSFSRIAYILPANESFGPLQISLGQTVKDIFKFMVIFIMVFLAFMIGMFNLYSYYRGAKV-----------------------------NRAFVTVEESFKTLFWSIFGLSEVASVVINYNHKFIENIGYILYGVYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARAKLWISYFEQGRTLPVPFNLVPSPKSAVQLLLAAARALGRLCRWRKHKGKLDVEMDMLDAKAKPNTLTQRALRSNMNRSMNSIGQHPTRYQQIMKRLIKRYVLKAQFDKENDEVNEGELKDIKQDISSLRYELLE 771 HSP 2 Score: 193.356 bits (490), Expect = 7.848e-107 Identity = 159/482 (32.99%), Postives = 235/482 (48.76%), Query Frame = 2
Query: 299 PDLMLDENRKNNYPNLERQFLLAVERSDIASIKRFL-DSSQKTGFNINCRDPLGRNXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQK----PSTDYTSNL--------SSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSY------MXXXXXXXXXXXRIEYNHLENDD----YRGNTP--TVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSS 1663
P M E R + E +FL A E +I ++R L D N+NC D +G+NA+ +A+ E+ + L L +GDAL+ AI++ VE I+ +++ P T + + F+PDITPIILA+H YEI+ +LL RG RI +PHD C C C E Q+ D+ HS+SRINAY+ LASP+ ++LSS+DP+LTA ELS EL L +E EFK +Y+ LS +C+DF LL+ R +EE+ +LN + LN D L RLKLAIKY K K+G + ++ PF+KF+ H++S+ ++ +++ N E D +R T T E +++ +I G IW E KELW G+K Y+ +WN+LDF S++VA+ + R A+ K+S
Sbjct: 26 PAYMFSE-RATSLTAEEERFLDAAEYGNIPVVRRMLEDGGAGRSLNVNCVDYMGQNAMQLAVGNEHLEVAELLLKRDKLSRVGDALMLAISKGYVRIVEAILAHPAFAGEKRLILSPREQETQDDDFYAYDEDGTRFSPDITPIILAAHCQEYEIVHILLRRGARIERPHDYFCKCGECTEKQRHDAFSHSRSRINAYRGLASPAYLSLSSEDPVLTALELSNELAMLANIEKEFKNDYKKLSVQCKDFVVGLLDLCRDTEEVEAILN------GDAELNPPACDR--QRAALIRLKLAIKYEVK------------------------------KIGKV-------------------------LRSPFMKFVAHAASFTIFLALLVLNASDRFEGVKLLPNETETDHPQQLFRIKTTSFTWTELLIVAWIIGMIWAECKELWAEGLKEYLFQLWNVLDFGMLSIFVASFTARLFAFLKAS 443
BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001180.1 (pep scaffold:Pmarinus_7.0:GL486488:994:2494:1 gene:ENSPMAG00000001058.1 transcript:ENSPMAT00000001180.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 80.1073 bits (196), Expect = 4.064e-18 Identity = 37/82 (45.12%), Postives = 59/82 (71.95%), Query Frame = 1
Query: 2044 EIVQSLYWSTYGLVDLSNLNLEYPH-QFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISY 2286
E Q L+W+ +G+ D ++ P+ + +FVG+ ++G Y+ I IVLLNMLIAM+ +S++ I + AD+EWKFARS+L++SY
Sbjct: 21 ETFQYLFWTVFGMEDRRTTDI--PNFEIAQFVGRSLYGVYAIIMAIVLLNMLIAMITSSFERIEDDADVEWKFARSRLYLSY 100
BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007332.1 (pep scaffold:Pmarinus_7.0:GL483392:1130:9476:1 gene:ENSPMAG00000006613.1 transcript:ENSPMAT00000007332.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.9442 bits (180), Expect = 2.488e-13 Identity = 59/225 (26.22%), Postives = 98/225 (43.56%), Query Frame = 1
Query: 1732 LFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNL-NLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKK 2403
L A A F ++L+ + + GP I + ++ D+ +F ++ + VAF L L + V D P N S +T + + ++ L++S +G+ D ++L ++ + FG Y +TLIVL+N+LIAMM+ +YQ I Q+D +WKF R L + T P P N++ W C C+ KK
Sbjct: 435 LLAKALAFCCVQLLDFLSFHHLFGPWAIIISDLMKDLARFGMVLGIFHVAFTLHLTALC-----QPVYPQGD-------PVGNSSTAAAAWDPSTAAQ---TTLDVTVLLFFSLFGMGDQNSLPDVSRSPSIVSTLVNATFGVYLIVTLIVLINLLIAMMSDTYQRIQAQSDTQWKFGRVVL-VREATRRTTPPAPLNVVTQ-------LLWLLQRCACRKACKK 636
BLAST of Short transient receptor potential channel 4 vs. Ensembl Yeast
Match: HBS1 (GTPase with similarity to translation release factors; together with binding partner Dom34p, facilitates ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, particularly in 3' UTRs; genetically implicated in mRNA no-go decay; HBS1 has a paralog, SKI7, that arose from the whole genome duplication [Source:SGD;Acc:S000001792]) HSP 1 Score: 58.9214 bits (141), Expect = 6.307e-9 Identity = 30/103 (29.13%), Postives = 58/103 (56.31%), Query Frame = 1
Query: 3952 NFAFIGYPKSGKSTVLGNILLHLNIFDEAFIKKTGWEATKLDSVYSKIAWLLDSSNNERDFKETI-LSSFHFVEINGKSFNLIDCPGNLCYYLQIIKAIMKTD 4257
+F +G+ +GKST++G +L LNI +++ ++K E+ + K AW++D +N ER+ T+ + + HF + +F ++D PG+ + I I + D
Sbjct: 169 SFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNEERERGVTVSICTSHF-STHRANFTIVDAPGHRDFVPNAIMGISQAD 270
BLAST of Short transient receptor potential channel 4 vs. Ensembl Yeast
Match: SUP35 (Translation termination factor eRF3; has a role in mRNA deadenylation and decay; altered protein conformation creates the [PSI(+)] prion that modifies cellular fitness, alters translational fidelity by affecting reading frame selection, and results in a nonsense suppressor phenotype; many stress-response genes are repressed in the presence of [PSI(+)] [Source:SGD;Acc:S000002579]) HSP 1 Score: 53.9138 bits (128), Expect = 1.799e-7 Identity = 27/99 (27.27%), Postives = 51/99 (51.52%), Query Frame = 1
Query: 3961 FIGYPKSGKSTVLGNILLHLNIFDEAFIKKTGWEATKLDSVYSKIAWLLDSSNNERDFKETILSSFHFVEINGKSFNLIDCPGNLCYYLQIIKAIMKTD 4257
F+G+ +GKST+ GN+L D+ I+K EA ++W++D++ ER+ +TI + E + + ++D PG+ Y ++I + D
Sbjct: 265 FMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNKEERNDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQAD 363
BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO45311 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSZ7]) HSP 1 Score: 186.422 bits (472), Expect = 4.345e-66 Identity = 112/333 (33.63%), Postives = 185/333 (55.56%), Query Frame = 2
Query: 680 PIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNH--SNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNEN 1672
P+++A+ NYE++ +L+ +G ++ KPH++ C C+ C + D+ R S+ R++ Y+ LA+P I+++S DP LTAFELS EL+ + R E+E++ +Y LS +C F LL++ R S E +LN+ NGS + N+ L+++ AI YNQK FVAHP CQ L+ + + G+R FLY++ + +FP+LA IY P +K+PF+KFI H+SS+++FL+LL + +H +R P+ +EW++ +I G W E K++W G + Y WN +D L + L + + + N
Sbjct: 1 PLVVAAQLGNYEVLNMLVSKGFQLVKPHNVLCRCEEC----QADNFRESQRRLDIYRGLANPVFISMTSNDPFLTAFELSSELEVIARREDEYEKDYLQLSQQCSQFTIGLLDECRTSREQRCILNYPGENGSVEDYA---ENSLGLVNS--------AISYNQKEFVAHPFCQHLVMQHIFGDITGWRTNHFLYRIAYVLTQVIIFPVLAVIYFFMPFLEVGRKIKRPFVKFINHTSSFVVFLILLA-----VSSHHQFEIRFR-KMPSGLEWLIFSWILGVAWSECKQVWHEGARRYFSSGWNWMDIGMVFLLLGAFVLWTIIFIVDFDSN 312 HSP 2 Score: 85.8853 bits (211), Expect = 4.345e-66 Identity = 57/192 (29.69%), Postives = 96/192 (50.00%), Query Frame = 1
Query: 1723 SECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDG 2298
++ ++A + S +L+Y+ ++ LG LQ+SL RM+ I +F I +VL +F+ + L Y LP +N + A K + +L + +L W++ +V L LN+ +F +F Y +++VLLNMLIAMM+ SYQ + + + E+KFAR++LW Y D
Sbjct: 324 ADGMYAFGVVASFFRLIYLCQISRYLGLLQLSLSRMVRVIFQFAFISCVVLWSFSVAMTMLY-----------MSSFEAYQLPRP--VKNVTSDIDAILDKGYDNLLSTMVTLMWASLDMVGLDTLNVFKKQSLIQFWTAALFTLYHAASMVVLLNMLIAMMSNSYQQVEDNIETEYKFARTQLWTDYIGDA 502
BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO48346 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJX1]) HSP 1 Score: 143.665 bits (361), Expect = 7.161e-56 Identity = 99/320 (30.94%), Postives = 160/320 (50.00%), Query Frame = 2
Query: 674 ITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG---LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSY-MXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYV 1621
+TP+ILASH ++Y+I+KLLL +G I + HD C C C + + H A + SL LS KDP+ AFEL+ EL L +E EF+++Y LS +CE+FA ALL+Q R E+ + ++ + D + +G L L AI FVAHP+CQ +L S+ Y + + K+ + P+ A +Y P S + + P +KFI H+ ++ + LLL++ + R ++ + N + ++ I+I G I QE+K++W G + Y+ WNL+ A L++
Sbjct: 64 MTPLILASHNNSYDIVKLLLSKGHTIDRVHDRGCLCPWCQSLGRIGTSLHRLYTYRALASPVYMSLTFLSCKDPVRQAFELNKELVELADIEYEFRSDYLQLSQQCEEFAVALLDQCRDMSEI------------EQMMSVPDMDGALTKNGSKSLGVLDYAINNKNGRFVAHPYCQMMLNSVIYGDFHTWEKMGVTLKILFALLFTIFIPVWAIVYFFTPTSCLSQKLATPILKFIMHTGAFGLFLLLLILSSIQRFISSNTFLLKFLFNFSDI---LITIWIFGLIVQELKDMWRQGKERYLSQWWNLVTLAMLGLFI 368 HSP 2 Score: 94.3597 bits (233), Expect = 7.161e-56 Identity = 65/225 (28.89%), Postives = 120/225 (53.33%), Query Frame = 1
Query: 1699 DSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLL--WFYAKKRVETCSDDKNKYFLPTNNYSQNELYN-YCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLE--YPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLF 2358
+SY L++ F + + L VN LGPLQ+SL +M+ DI+KF L++ L+ +AF L ++ + +A K T S LY+ +C+ +G ++ ++W+ + +L N + +P + T+ G+++F ++ +++V +NMLIAMM+ S+Q +A+ D WKF+R+++W+ Y G+ LP PF+++ S +I F
Sbjct: 390 ESYRFILLANAFFTIGVLLAFLHFSNAVQVNSTLGPLQLSLVKMVKDILKFLLLFFLIYLAFVVALRRVYSQYVWAGKTPHTIS-----------------LYSVFCSVQGS--------MRLVFWAIFDKTELEEFNTDPSFPTKITQSTGEVLFALFNIASILVAINMLIAMMSNSFQKVADSEDFLWKFSRTRMWMEYIIKGSVLPAPFSVLPSIASIINFF 589
BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO49302 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH68]) HSP 1 Score: 127.102 bits (318), Expect = 7.261e-32 Identity = 103/349 (29.51%), Postives = 177/349 (50.72%), Query Frame = 2
Query: 674 ITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKS------RINAYQXXXXXXXXXXX------XKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG----LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYK-----VGMIFGI--SAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAY 1651
++P++LA H + ++II+L L +G R+ +PHD D + + + S R+NAY+ALASP I+ + PI EL+ +LK + EF +Y+ +S C+ FA LLEQ R ++E +LL+ + + E++ + +H L+ L LAI+ + VAHP Q L + Y GL F+R P +++ G +F + + + P LA Y+I P + ++K P +KF H+ +++LF + L +++ + DY P +I+W ++++ G QEVK+L+ G YI WN++ L++ + SLR AY
Sbjct: 122 VSPLMLAVHLEKFDIIELFLSKGYRVLEPHDDDDEDDDDEQLNRTNVGLELSSELSFNLRVNAYRALASPLYISYFFIMNPDALHPIFHVLELNKKLKNQMYRDFEFNNDYKQISKDCQRFAVDLLEQCRTTDETNVLLDVYP---EIQRVYEKDKKHIEGSHTAFKELSMLNLAIRNDMNELVAHPQSQLRLDKILYHGLYMFKREPRVWRYRSWYTGKLFWLRHTLLLPFLALFYIIAPDCRISNVLKTPMVKFYSHTGAFVLFAIALAVSSFEDHFT-----DYTL-IPVLIDWGTLLFVLGLFLQEVKDLYFQGAFRYIRQWWNIISLLMVVLFLISYSLRLTAY 461 HSP 2 Score: 30.4166 bits (67), Expect = 7.261e-32 Identity = 23/68 (33.82%), Postives = 39/68 (57.35%), Query Frame = 1
Query: 1714 TLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFY 1917
+L++ FA A +FS + L V+ GPLQ+SL + D++KFF+ + ++ +AF L +L Y
Sbjct: 482 SLLANSFFAFAMVFSFIHLTNFLQVSDVFGPLQLSLYMLFADLIKFFVFFFVLFLAFGLSLRKLYSHY 549
BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO31100 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYW3]) HSP 1 Score: 74.3294 bits (181), Expect = 3.054e-20 Identity = 49/202 (24.26%), Postives = 103/202 (50.99%), Query Frame = 1
Query: 1732 LFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISP 2337
++ +F L++ + +N GPLQ++L RML D+ + +++V++AF+ + ++ ++A++ + + N YS +C G L + +SL WS +GL DL ++ ++ + ++ + I +++LLN L+A++N +Y+ I +D EWK+ R+ ++ + + P P N+I P
Sbjct: 559 MYGINTLFLILRVSSVLELNRTTGPLQLALMRMLVDLWVIIVQFVVVILAFSFAITKV--YFAQRSLAMGQTETNA------TYS-----GFCPLDGG--NCLRKTTESLVWSLFGLTDLDSIATN--NRAASTLAYYLYAIFLVICVVMLLNTLVALLNNTYEDIKSNSDTEWKYVRA-MYADQYNRCHPFPPPVNLITVP 742 HSP 2 Score: 44.2838 bits (103), Expect = 3.054e-20 Identity = 20/61 (32.79%), Postives = 33/61 (54.10%), Query Frame = 2
Query: 1478 PTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKS 1660
PT +E++++++ G I EV++ + K Y DMWN LD Y+ + +R V KS
Sbjct: 484 PTAVEYVILVFFLGRILAEVQQYQRSRSKIYFRDMWNYLDITIILCYITIVIVRIVTMAKS 544
BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO31202 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYL0]) HSP 1 Score: 79.7221 bits (195), Expect = 9.245e-18 Identity = 36/85 (42.35%), Postives = 60/85 (70.59%), Query Frame = 1
Query: 2050 VQSLYWSTYGLVDLSNLNL-EYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGN 2301
+ SL+WS +GL +L++ + T+ G++MFG + I +IV +NMLIAMM S++ IAEQAD++WK +R++LW+S+ + G+
Sbjct: 1 LNSLFWSVFGLTELNSFGTNDAKFTITKETGEVMFGFFQVIAVIVAVNMLIAMMTRSFESIAEQADVKWKVSRTRLWMSWIQKGS 85
BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc4a (transient receptor potential cation channel subfamily C member 4 [Source:NCBI gene;Acc:101170611]) HSP 1 Score: 378.637 bits (971), Expect = 0.000e+0 Identity = 230/446 (51.57%), Postives = 314/446 (70.40%), Query Frame = 2
Query: 341 NLERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHG---LARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSN 1666
NLE+ +L AVE+ D AS+K+ L+ ++ NINC DPLGR A+LIAIE E++E++ELLL +++ +GDALLHAI +E AVE+++N + + S FTPDITPIILA+H +NYEIIKLL+ +G +P+PH++RC C CV S DSLRHS+SR+N Y+AL+SPSLIALSS+DP LTAF LSWEL+ L ++ENEFK+EYE LS +C+ FA+ LL+QTR S EL ++LN+ R+ +L+D G LARLKLAIKY+QK FVA P+CQQLLAS WY+ PG+RRR + K+ I +FP+ A YLI P+S + ++KPFIKFICH++SY+ FL LL+LA+ I + + +G PT +EW+++ ++ GFIW E+K++W+ G + YI D WNL+DF NSLY+ATISL+ VAY K S
Sbjct: 31 NLEKAYLGAVEKGDYASVKQALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGGMQVPPILLDKQYSDFTPDITPIILAAHTNNYEIIKLLVQKGVSMPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALSSPSLIALSSEDPFLTAFRLSWELQELSKVENEFKSEYEELSQQCKQFAKDLLDQTRSSRELEMILNY------------RDDINLLDDEGNNELARLKLAIKYHQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLLFPLFAFCYLIAPKSRYGNFIRKPFIKFICHTASYLTFLFLLLLASQHIVATEQDRQNRQGPAPTTVEWMILPWVLGFIWAEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYTKYSG 464 HSP 2 Score: 305.064 bits (780), Expect = 0.000e+0 Identity = 157/312 (50.32%), Postives = 213/312 (68.27%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKS--RWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNN 2613
R +W+ + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y K SD++ K C + F+SLFE +QSL+WS +GL+ L N++ HQFTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQ IA+ ADIEWKFAR+KLW+SYFE+G TLP PFNII SPK+ +YL W K +CK KS + ++ + ++ +YQ+V+ NL+ RY+ + A+ EG+TED+ E+K DIS+FR+E++ ++K
Sbjct: 468 RNQWEMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETK----ASDERGKC-----------KGIRCVEQNNAFSSLFETLQSLFWSIFGLISLYVTNVDADHQFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGATLPTPFNIIPSPKSFWYLMCWIKRR-VCKRTRLKSAENFGTLGRRAAENLRTNHQYQEVLRNLVKRYVAAMIRDAKTEEGLTEDNFKELKQDISSFRYEVMGMMKTG 763
BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc4b (short transient receptor potential channel 4 [Source:NCBI gene;Acc:101154885]) HSP 1 Score: 375.17 bits (962), Expect = 0.000e+0 Identity = 235/451 (52.11%), Postives = 322/451 (71.40%), Query Frame = 2
Query: 344 LERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEY---NHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIISW 1684
+E+ +L AVE+ D S+K+ L+ ++ NINC D LGR A+LIAIE E++E++ELLL Y++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYE+IKLLL RG IP+PH +RC+C C+ S D LR+S+SR+N Y+ALASPSLIALSS+DP LTAF+LSWELK L R+ENEFK+EYE LS C+ FA+ LL+QTR S+EL I+LN+ + N L+E T+ LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ F I +FP+L+ YLI+P+S + L++KPF+KFICH++SY+ FLLLL LA+ I+ N L + D +G PT +EW+++ +I GFIW E+K++W+NG++ Y D WN++DF NSLY+ATI+L+ VAY K N + W
Sbjct: 32 MEKAYLGAVEKGDYGSVKQALEEAEIYFRININCIDSLGRTALLIAIENENLEIIELLLSYNVHVGDALLHAIRKEVVGAVELLLNHKKPRGEKQVPGILLDKQFSDFTPDITPIILAAHTNNYEVIKLLLQRGVSIPQPHAVRCSCVECMSSTDVDCLRYSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELKELSRVENEFKSEYEELSHTCKQFAKDLLDQTRSSKELEIILNYRDD--INPILDE-------STNDLARLKLAIKYCQKEFVAQPNCQQLLASRWYDKFPGWRRRHWAGKLITCFFIGLLFPLLSIFYLIFPKSRYGLLIRKPFVKFICHTASYLTFLLLLFLASQHIDSTGPNSLSH-DVQGPPPTTVEWMILPWIIGFIWTEIKQMWDNGLEDYADDWWNIMDFIMNSLYLATIALKIVAYVKMKNHCMDDW 472 HSP 2 Score: 293.123 bits (749), Expect = 0.000e+0 Identity = 154/317 (48.58%), Postives = 209/317 (65.93%), Query Frame = 1
Query: 1696 WDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRY-----------QKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
W+ + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++YA +++K+ Y + C + F++LFE VQSL+WS +GLV L N++ PH+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQ IA+ AD+EWKFAR+KLW+SYFE+G TLP PFNII SPK++ YLF W + C+ K+ R + RY +V+ NL+ RY+ + A+ EG+TE++ E+K DIS+FR+E+L ++K
Sbjct: 472 WEVWHPTLLAESLFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYA-------TEEKSCYGI------------RCLQQNNAFSTLFETVQSLFWSVFGLVSLYVTNVKPPHEFTEFVGTTMFGTYNIISLVVLLNMLIAMMNNSYQHIADHADMEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSVCYLFGWIRKR-FCRKPAKRIR--------QTFETLGVRYFQSYLLNIYFFSEVLKNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVLGMMKG 760
BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc5a (short transient receptor potential channel 5 [Source:NCBI gene;Acc:101169488]) HSP 1 Score: 374.015 bits (959), Expect = 0.000e+0 Identity = 227/438 (51.83%), Postives = 308/438 (70.32%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKT-GFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER +L AVE+ D A +K L ++ ++NC DPLGR+ +LIAIE E++E++ELLL + + GDALL+AI +E AVE++++ + +++ + + S FTPDITPI+LA+H +NYEIIKLL+ R IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEF+ EYE LS +C+ FA+ LL+Q R S EL +LNH + S L+ R H LA+LKLAIKY+QK FVA P+CQQLLA+LWY+G PG+RR + K+ F I +FP+ + IYL+ P+S +KKPFIKFICH++SY+ FL LL+LA+ I +L +G PTV+EW+++ ++ GFIW E+KE+W+ G YI D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 36 ERAYLTAVEKGDYAGVKHALREAEVYYNMDVNCLDPLGRSGLLIAIENENLEIMELLLDHGIHTGDALLYAIRKEVVGAVELLLSHRRPSGEKQVPSLMMDSQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKRFAKDLLDQARSSRELETILNHRDSDQSEE-LDPRQC------HDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRHHWAVKLVTCFIIGLLFPVFSMIYLLAPKSALGRFIKKPFIKFICHTASYLTFLFLLLLASQHIARTNLH---MQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVK 463 HSP 2 Score: 308.145 bits (788), Expect = 0.000e+0 Identity = 158/316 (50.00%), Postives = 220/316 (69.62%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSK---GKKS-RWHSIKKIVSKVNE---MEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y K E ++ K C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+++YL W N LC+ G++S + ++++ + + Q YQ+V+ NL+ RY+ + A+ +EG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 470 REEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETKASEEPNNCKGIR---------------CERQNNAFSTLFETLQSLFWSIFGLLNLYVTNVKARHEFTEFVGATMFGTYNIISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSVWYLLMWLH-NRLCRRGQPPGEESHKCENLREFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRSAKTDEGLTEENFKELKQDISSFRYEVLDLLGN 769
BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc5a (short transient receptor potential channel 5 [Source:NCBI gene;Acc:101169488]) HSP 1 Score: 373.629 bits (958), Expect = 0.000e+0 Identity = 227/438 (51.83%), Postives = 308/438 (70.32%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKT-GFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
ER +L AVE+ D A +K L ++ ++NC DPLGR+ +LIAIE E++E++ELLL + + GDALL+AI +E AVE++++ + +++ + + S FTPDITPI+LA+H +NYEIIKLL+ R IP+PH +RC C CV S + DSLRHS+SR+N Y+ALASPSLIALSS+DPILTAF L WELK L ++ENEF+ EYE LS +C+ FA+ LL+Q R S EL +LNH + S L+ R H LA+LKLAIKY+QK FVA P+CQQLLA+LWY+G PG+RR + K+ F I +FP+ + IYL+ P+S +KKPFIKFICH++SY+ FL LL+LA+ I +L +G PTV+EW+++ ++ GFIW E+KE+W+ G YI D WNL+DFA NSLY+ATISL+ VAY K
Sbjct: 33 ERAYLTAVEKGDYAGVKHALREAEVYYNMDVNCLDPLGRSGLLIAIENENLEIMELLLDHGIHTGDALLYAIRKEVVGAVELLLSHRRPSGEKQVPSLMMDSQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKRFAKDLLDQARSSRELETILNHRDSDQSEE-LDPRQC------HDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRHHWAVKLVTCFIIGLLFPVFSMIYLLAPKSALGRFIKKPFIKFICHTASYLTFLFLLLLASQHIARTNLH---MQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVK 460 HSP 2 Score: 303.523 bits (776), Expect = 0.000e+0 Identity = 157/309 (50.81%), Postives = 214/309 (69.26%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
R +W+ + PTLI+E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++Y K E ++ K C + F++LFE +QSL+WS +GL++L N++ H+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQLIA+ ADIEWKFAR+KLW+SYF++G TLP PFNII SPK+++YL W N LC+ +G+ S K E + + +V+ NL+ RY+ + A+ +EG+TE++ E+K DIS+FR+E+LD+L N
Sbjct: 467 REEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETKASEEPNNCKGIR---------------CERQNNAFSTLFETLQSLFWSIFGLLNLYVTNVKARHEFTEFVGATMFGTYNIISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSVWYLLMWLH-NRLCR-RGQPPGEESHK------CENLREFTEVIRNLVKRYVAAMIRSAKTDEGLTEENFKELKQDISSFRYEVLDLLGN 752
BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc4b (short transient receptor potential channel 4 [Source:NCBI gene;Acc:101154885]) HSP 1 Score: 371.703 bits (953), Expect = 0.000e+0 Identity = 233/442 (52.71%), Postives = 319/442 (72.17%), Query Frame = 2
Query: 344 LERQFLLAVERSDIASIKRFLDSSQ-KTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEY---NHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYK 1657
+E+ +L AVE+ D S+K+ L+ ++ NINC D LGR A+LIAIE E++E++ELLL Y++ +GDALLHAI +E AVE+++N + +++ S FTPDITPIILA+H +NYE+IKLLL RG IP+PH +RC+C C+ S D LR+S+SR+N Y+ALASPSLIALSS+DP LTAF+LSWELK L R+ENEFK+EYE LS C+ FA+ LL+QTR S+EL I+LN+ + N L+E T+ LARLKLAIKY QK FVA P+CQQLLAS WY+ PG+RRR + K+ F I +FP+L+ YLI+P+S + L++KPF+KFICH++SY+ FLLLL LA+ I+ N L + D +G PT +EW+++ +I GFIW E+K++W+NG++ Y D WN++DF NSLY+ATI+L+ VAY K
Sbjct: 32 MEKAYLGAVEKGDYGSVKQALEEAEIYFRININCIDSLGRTALLIAIENENLEIIELLLSYNVHVGDALLHAIRKEVVGAVELLLNHKKPRGEKQVPGILLDKQFSDFTPDITPIILAAHTNNYEVIKLLLQRGVSIPQPHAVRCSCVECMSSTDVDCLRYSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELKELSRVENEFKSEYEELSHTCKQFAKDLLDQTRSSKELEIILNYRDD--INPILDE-------STNDLARLKLAIKYCQKEFVAQPNCQQLLASRWYDKFPGWRRRHWAGKLITCFFIGLLFPLLSIFYLIFPKSRYGLLIRKPFVKFICHTASYLTFLLLLFLASQHIDSTGPNSLSH-DVQGPPPTTVEWMILPWIIGFIWTEIKQMWDNGLEDYADDWWNIMDFIMNSLYLATIALKIVAYVK 463 HSP 2 Score: 293.893 bits (751), Expect = 0.000e+0 Identity = 154/317 (48.58%), Postives = 209/317 (65.93%), Query Frame = 1
Query: 1696 WDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRY-----------QKVMNNLIMRYLLHR-QKAEDNEGVTEDDLNEIKGDISAFRFELLDILKN 2610
W+ + PTL++E LFA ANIFS+L+L+ +FT N +LGPLQISLGRML DI+KF IY LVL+AFA GLNQL ++YA +++K+ Y + C + F++LFE VQSL+WS +GLV L N++ PH+FTEFVG MFGTY+ I+L+VLLNMLIAMMN SYQ IA+ AD+EWKFAR+KLW+SYFE+G TLP PFNII SPK++ YLF W + C+ K+ R + RY +V+ NL+ RY+ + A+ EG+TE++ E+K DIS+FR+E+L ++K
Sbjct: 470 WEVWHPTLLAESLFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYA-------TEEKSCYGI------------RCLQQNNAFSTLFETVQSLFWSVFGLVSLYVTNVKPPHEFTEFVGTTMFGTYNIISLVVLLNMLIAMMNNSYQHIADHADMEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSVCYLFGWIRKR-FCRKPAKRIR--------QTFETLGVRYFQSYLLNIYFFSEVLKNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVLGMMKG 758
BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000001959.1 (SMESG000001959.1) HSP 1 Score: 1118.22 bits (2891), Expect = 0.000e+0 Identity = 615/623 (98.72%), Postives = 618/623 (99.20%), Query Frame = 1
Query: 3361 MFKKQSFYTXXXXXXXXXXXXXXXFTELDLDEVDRSINKIINPNFKKPQLKEDKPIFNILTSLSSQKKIITSSYHYDEPQKILFPDNYKPNMKSYNKSYIFSKYIQPLSIEYLRKWTRYCSKHKVFNFEEISEKLSVKPEIKKILPNKFCLGTDIVPSYLSKKTKAVKSIKDIKPEIQFQSVLKAFKSFKGYVSKENNFAFIGYPKSGKSTVLGNILLHLNIFDEAFIKKTGWEATKLDSVYSKIAWLLDSSNNERDFKETILSSFHFVEINGKSFNLIDCPGNLCYYLQIIKAIMKTDSVXXXXXXXXXXXXXTENFSDINYIYFLFHLLKIFKVDKLKIIFVNGFKTDSNVPLKKIEAIWRKFSKSQLTSIVVINDLANIQSSEIKSIIDHIGGDCPMKTNEIAHEIEKPLLIEIIDIFKPIESNLPVIVGRVIKGGVFSGINNAASKVVICPEKVSCTIKSLKIHEKGELITRSSAFPGHIVELTLPEIISEDKIKIGSFICHQEHLLTINQCFQVRLVIFDCDIRVPIINGMKVFMWTPSRTCFCQLTKMLSVEYYEHREKIVKKNPRIITQSECVVNALITSEDFLAVEFHSNHXXXXXXXXXXXXXXXAGKFIDIIK 5229
MFKKQSFYTKKSNNINSNELISSKFTELDLDEVDRSINKIINPNFKKPQLKEDKPIFNILTSLSSQKKIITSSYHYDEPQKILFPDNYKP MKSYNKSYIFSKYIQPLSIEYLRKWTRYCSKHKVFNFEEISEKLSVKPEIKKILPNKFCLGTDIVPSYLSKKTKAVKS KDIKPEIQFQSVLKAFKSFKGYVSKENNFAFIGYPKSGKSTVLGNILLHLNIFDEAFIKKTGWEATKLDSVYSKIAWLLDSSNNERDFKETILSSFH+VEINGKSFNLIDCPGNLCYYLQIIKAIMKTDSVILIINLIIDWNINTENFSDINYIYFLFHLLKIFKVDKLKIIFVNGFKTDSNVPLKKIEAIWRKFSKSQLTSIV+INDLANIQSSEIKSIIDHIGGDCPMKT EIAHEIEKPLL+EIIDIFKPIESNLPVIVGRVIKGGVFSGINNAASKVVICPEKV CTIKSLKIHEKGELITRSSAFPGHIVELTLPEIISEDKIKIGSFICHQEHLLTINQCFQVRLVIFDCDIRVPIINGMKVFMWTPSRTCFCQLTKMLSVEYYEHREKIVKKNPRIITQSECVVNALITSEDFLAVEFHSNHKLDL LLFSELKLFSAGKFIDIIK
Sbjct: 1 MFKKQSFYTKKSNNINSNELISSKFTELDLDEVDRSINKIINPNFKKPQLKEDKPIFNILTSLSSQKKIITSSYHYDEPQKILFPDNYKPTMKSYNKSYIFSKYIQPLSIEYLRKWTRYCSKHKVFNFEEISEKLSVKPEIKKILPNKFCLGTDIVPSYLSKKTKAVKSKKDIKPEIQFQSVLKAFKSFKGYVSKENNFAFIGYPKSGKSTVLGNILLHLNIFDEAFIKKTGWEATKLDSVYSKIAWLLDSSNNERDFKETILSSFHYVEINGKSFNLIDCPGNLCYYLQIIKAIMKTDSVILIINLIIDWNINTENFSDINYIYFLFHLLKIFKVDKLKIIFVNGFKTDSNVPLKKIEAIWRKFSKSQLTSIVIINDLANIQSSEIKSIIDHIGGDCPMKTIEIAHEIEKPLLLEIIDIFKPIESNLPVIVGRVIKGGVFSGINNAASKVVICPEKVLCTIKSLKIHEKGELITRSSAFPGHIVELTLPEIISEDKIKIGSFICHQEHLLTINQCFQVRLVIFDCDIRVPIINGMKVFMWTPSRTCFCQLTKMLSVEYYEHREKIVKKNPRIITQSECVVNALITSEDFLAVEFHSNHKLDLLLLFSELKLFSAGKFIDIIK 623
BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000039904.1 (SMESG000039904.1) HSP 1 Score: 954.896 bits (2467), Expect = 0.000e+0 Identity = 516/517 (99.81%), Postives = 517/517 (100.00%), Query Frame = 1
Query: 1681 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNVXXXXXXXXXXXXXXXXXXXXXXNQRFDTRSSTNTIDQLGSISEISTPMKSKKSLISYTSLEKSKPTTKYKKDRPKKSFSLEDEPSVSFATDLEIFAYESRENSSKLSKVTXXXXXXXXXXXXHTMTSRSVPNIPPNIEKNQKNLSSVDTXXXXXXXXXXXXQPLRQYNLNNSSPTLNRIYFCQDNLDVSKETRSKRSDLV 3231
MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNVSSDRGLRSKLRRKGSKKSMSRLNQRFDTRSSTNTIDQLGSISEISTPMKSKKSLISYTSLEKSKPTTKYKKDRPKKSFSLEDEPSVSFATDLEIFAYESRENSSKLSKVTNKLFSKKFNKKSHT+TSRSVPNIPPNIEKNQKNLSSVDTISRSNIIPSISSQPLRQYNLNNSSPTLNRIYFCQDNLDVSKETRSKRSDLV
Sbjct: 503 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNVSSDRGLRSKLRRKGSKKSMSRLNQRFDTRSSTNTIDQLGSISEISTPMKSKKSLISYTSLEKSKPTTKYKKDRPKKSFSLEDEPSVSFATDLEIFAYESRENSSKLSKVTNKLFSKKFNKKSHTLTSRSVPNIPPNIEKNQKNLSSVDTISRSNIIPSISSQPLRQYNLNNSSPTLNRIYFCQDNLDVSKETRSKRSDLV 1019 HSP 2 Score: 918.687 bits (2373), Expect = 0.000e+0 Identity = 504/506 (99.60%), Postives = 504/506 (99.60%), Query Frame = 2
Query: 176 MDSMNLESISNNLHQKQNNARYNSIVPDNNQKLLHNSRIFLPDLMLDENRKNNYPNLERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIISWAGR 1693
MDSMNLESISNNLHQKQNNARYNSIVPDNNQKLLHNSRIFLPDLMLDENRKNNYPNLERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNAILIAIEYEHIELLELLLKYDLDLGDALLHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQALASPSLIALSSKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMLFLLLLILAALRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIIS GR
Sbjct: 1 MDSMNLESISNNLHQKQNNARYNSIVPDNNQKLLHNSRIFLPDLMLDENRKNNYPNLERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNAILIAIEYEHIELLELLLKYDLDLGDALLHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQALASPSLIALSSKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMLFLLLLILAALRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIIS-MGR 505
BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000039904.1 (SMESG000039904.1) HSP 1 Score: 954.896 bits (2467), Expect = 0.000e+0 Identity = 516/517 (99.81%), Postives = 517/517 (100.00%), Query Frame = 1
Query: 1681 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNVXXXXXXXXXXXXXXXXXXXXXXNQRFDTRSSTNTIDQLGSISEISTPMKSKKSLISYTSLEKSKPTTKYKKDRPKKSFSLEDEPSVSFATDLEIFAYESRENSSKLSKVTXXXXXXXXXXXXHTMTSRSVPNIPPNIEKNQKNLSSVDTXXXXXXXXXXXXQPLRQYNLNNSSPTLNRIYFCQDNLDVSKETRSKRSDLV 3231
MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNVSSDRGLRSKLRRKGSKKSMSRLNQRFDTRSSTNTIDQLGSISEISTPMKSKKSLISYTSLEKSKPTTKYKKDRPKKSFSLEDEPSVSFATDLEIFAYESRENSSKLSKVTNKLFSKKFNKKSHT+TSRSVPNIPPNIEKNQKNLSSVDTISRSNIIPSISSQPLRQYNLNNSSPTLNRIYFCQDNLDVSKETRSKRSDLV
Sbjct: 500 MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNVSSDRGLRSKLRRKGSKKSMSRLNQRFDTRSSTNTIDQLGSISEISTPMKSKKSLISYTSLEKSKPTTKYKKDRPKKSFSLEDEPSVSFATDLEIFAYESRENSSKLSKVTNKLFSKKFNKKSHTLTSRSVPNIPPNIEKNQKNLSSVDTISRSNIIPSISSQPLRQYNLNNSSPTLNRIYFCQDNLDVSKETRSKRSDLV 1016 HSP 2 Score: 912.909 bits (2358), Expect = 0.000e+0 Identity = 501/503 (99.60%), Postives = 501/503 (99.60%), Query Frame = 2
Query: 185 MNLESISNNLHQKQNNARYNSIVPDNNQKLLHNSRIFLPDLMLDENRKNNYPNLERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIISWAGR 1693
MNLESISNNLHQKQNNARYNSIVPDNNQKLLHNSRIFLPDLMLDENRKNNYPNLERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNAILIAIEYEHIELLELLLKYDLDLGDALLHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQALASPSLIALSSKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMLFLLLLILAALRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIIS GR
Sbjct: 1 MNLESISNNLHQKQNNARYNSIVPDNNQKLLHNSRIFLPDLMLDENRKNNYPNLERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNAILIAIEYEHIELLELLLKYDLDLGDALLHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQALASPSLIALSSKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMLFLLLLILAALRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIIS-MGR 502
BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000077497.1 (SMESG000077497.1) HSP 1 Score: 540.421 bits (1391), Expect = 9.582e-172 Identity = 249/313 (79.55%), Postives = 280/313 (89.46%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTV 2625
RPKWDSYDP LISECLF+AANIFSTLKLV IFT+NP+LGPLQISLGRMLNDI+KFF +YMLVL+AFACGLNQLLWFYAKKR + C+ +++F P+ ++LYNYCATRGKYFT+LFEIVQSLYWSTYGLVDL+ LNLEYPH+FTEFVGKLMFG YS ITL+VLLNMLIAMMNTSYQ+I E+ADIEWKFARSKLWISYFEDGNTLPVPFNIIISPK IYY W +N CKSKG+KS+W SIKKIV+KVNEMEQRYQKVM NL+MRYL+ RQK ED + VTEDD+NEIKGDISAFR+ELLDILK+NGM +
Sbjct: 456 RPKWDSYDPILISECLFSAANIFSTLKLVSIFTMNPHLGPLQISLGRMLNDILKFFCVYMLVLIAFACGLNQLLWFYAKKRRDICAKSSHRFFQPSEKEPVSDLYNYCATRGKYFTNLFEIVQSLYWSTYGLVDLTYLNLEYPHEFTEFVGKLMFGVYSVITLVVLLNMLIAMMNTSYQIIVEKADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKAIYYFLRWIHLNWFCKSKGRKSKWQSIKKIVTKVNEMEQRYQKVMENLVMRYLMLRQKKEDKQEVTEDDINEIKGDISAFRYELLDILKSNGMDI 768 HSP 2 Score: 533.102 bits (1372), Expect = 5.913e-169 Identity = 310/471 (65.82%), Postives = 374/471 (79.41%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSN-ENIIS-----WAGRNGIPTTQHLYQ--NVF 1735
ER FL+AVERSDI+++K +LD++ FNINCRD LGRNA+LIAI+ EH +LL+LLL+Y++DL DALL AI+EE+ E+VE+II AQ + K + S+L SSFTPDITPIILA+H+DNYEIIK+LLDRGDRIPKPHDLRC+C ICVE+QK DSL HS SRINAY+ALASP LIALSSKDP+LTAFELSWEL RL RLENEF +EYE LS KCE+FA ALLEQTR S ELA+LLNH++ S +N+ N TH L RLKLAIKYNQKSFVA+PHCQQLLAS WYEGLPGFRR+PF+YK+ +I + MFP L +YL++PRS LM+KPFIKFICHS+SY++FL LLILAALRIE+ + E + R N PT IE +L++YI GFIWQE+KELW GVK YIMDMWNLLDFATN+LYVATISLRAVAYYK +N EN++ W + I ++ L+ N+F
Sbjct: 11 ERLFLMAVERSDISTVKSYLDNAAVLNFNINCRDSLGRNAVLIAIDNEHTDLLQLLLQYEMDLSDALLRAIDEEHLESVELIIAAQSTKTEDKNIDESRSSLISSFTPDITPIILAAHKDNYEIIKVLLDRGDRIPKPHDLRCSCQICVEAQKIDSLHHSMSRINAYKALASPCLIALSSKDPVLTAFELSWELSRLSRLENEFASEYEKLSKKCEEFATALLEQTRESSELAVLLNHNSTSVG---VNDINYGDSFQTHSLTRLKLAIKYNQKSFVANPHCQQLLASFWYEGLPGFRRKPFIYKLTIISALGFMFPGLGVVYLVFPRSKIGRLMRKPFIKFICHSASYIIFLALLILAALRIEFTNSEVMESRQNPPTAIECLLVVYICGFIWQEIKELWIAGVKCYIMDMWNLLDFATNALYVATISLRAVAYYKFNNVENLLQEQRPKWDSYDPILISECLFSAANIF 478
BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000077497.1 (SMESG000077497.1) HSP 1 Score: 540.806 bits (1392), Expect = 9.828e-172 Identity = 249/313 (79.55%), Postives = 280/313 (89.46%), Query Frame = 1
Query: 1687 RPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCLCKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTV 2625
RPKWDSYDP LISECLF+AANIFSTLKLV IFT+NP+LGPLQISLGRMLNDI+KFF +YMLVL+AFACGLNQLLWFYAKKR + C+ +++F P+ ++LYNYCATRGKYFT+LFEIVQSLYWSTYGLVDL+ LNLEYPH+FTEFVGKLMFG YS ITL+VLLNMLIAMMNTSYQ+I E+ADIEWKFARSKLWISYFEDGNTLPVPFNIIISPK IYY W +N CKSKG+KS+W SIKKIV+KVNEMEQRYQKVM NL+MRYL+ RQK ED + VTEDD+NEIKGDISAFR+ELLDILK+NGM +
Sbjct: 469 RPKWDSYDPILISECLFSAANIFSTLKLVSIFTMNPHLGPLQISLGRMLNDILKFFCVYMLVLIAFACGLNQLLWFYAKKRRDICAKSSHRFFQPSEKEPVSDLYNYCATRGKYFTNLFEIVQSLYWSTYGLVDLTYLNLEYPHEFTEFVGKLMFGVYSVITLVVLLNMLIAMMNTSYQIIVEKADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKAIYYFLRWIHLNWFCKSKGRKSKWQSIKKIVTKVNEMEQRYQKVMENLVMRYLMLRQKKEDKQEVTEDDINEIKGDISAFRYELLDILKSNGMDI 781 HSP 2 Score: 532.332 bits (1370), Expect = 1.425e-168 Identity = 310/471 (65.82%), Postives = 374/471 (79.41%), Query Frame = 2
Query: 347 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQXXXXXXXXXXXXKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSLIDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMXXXXXXXXXXXRIEYNHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSN-ENIIS-----WAGRNGIPTTQHLYQ--NVF 1735
ER FL+AVERSDI+++K +LD++ FNINCRD LGRNA+LIAI+ EH +LL+LLL+Y++DL DALL AI+EE+ E+VE+II AQ + K + S+L SSFTPDITPIILA+H+DNYEIIK+LLDRGDRIPKPHDLRC+C ICVE+QK DSL HS SRINAY+ALASP LIALSSKDP+LTAFELSWEL RL RLENEF +EYE LS KCE+FA ALLEQTR S ELA+LLNH++ S +N+ N TH L RLKLAIKYNQKSFVA+PHCQQLLAS WYEGLPGFRR+PF+YK+ +I + MFP L +YL++PRS LM+KPFIKFICHS+SY++FL LLILAALRIE+ + E + R N PT IE +L++YI GFIWQE+KELW GVK YIMDMWNLLDFATN+LYVATISLRAVAYYK +N EN++ W + I ++ L+ N+F
Sbjct: 24 ERLFLMAVERSDISTVKSYLDNAAVLNFNINCRDSLGRNAVLIAIDNEHTDLLQLLLQYEMDLSDALLRAIDEEHLESVELIIAAQSTKTEDKNIDESRSSLISSFTPDITPIILAAHKDNYEIIKVLLDRGDRIPKPHDLRCSCQICVEAQKIDSLHHSMSRINAYKALASPCLIALSSKDPVLTAFELSWELSRLSRLENEFASEYEKLSKKCEEFATALLEQTRESSELAVLLNHNSTSVG---VNDINYGDSFQTHSLTRLKLAIKYNQKSFVANPHCQQLLASFWYEGLPGFRRKPFIYKLTIISALGFMFPGLGVVYLVFPRSKIGRLMRKPFIKFICHSASYIIFLALLILAALRIEFTNSEVMESRQNPPTAIECLLVVYICGFIWQEIKELWIAGVKCYIMDMWNLLDFATNALYVATISLRAVAYYKFNNVENLLQEQRPKWDSYDPILISECLFSAANIF 491 The following BLAST results are available for this feature:
BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30006424 ID=SMED30006424|Name=Short transient receptor potential channel 4|organism=Schmidtea mediterranea sexual|type=transcript|length=5280bpback to top protein sequence of SMED30006424-orf-1 >SMED30006424-orf-1 ID=SMED30006424-orf-1|Name=SMED30006424-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=624bp MFKKQSFYTKKSNNINSNELISSKFTELDLDEVDRSINKIINPNFKKPQLback to top protein sequence of SMED30006424-orf-2 >SMED30006424-orf-2 ID=SMED30006424-orf-2|Name=SMED30006424-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=530bp MDSMNLESISNNLHQKQNNARYNSIVPDNNQKLLHNSRIFLPDLMLDENRback to top protein sequence of SMED30006424-orf-3 >SMED30006424-orf-3 ID=SMED30006424-orf-3|Name=SMED30006424-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=518bp MGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
