PRELI/MSF1 domain-containing protein

Overview
NamePRELI/MSF1 domain-containing protein
Smed IDSMED30006378
Length (bp)844
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of PRELI/MSF1 domain-containing protein (SMED30006378) t-SNE clustered cells

Violin plots show distribution of expression levels for PRELI/MSF1 domain-containing protein (SMED30006378) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PRELI/MSF1 domain-containing protein (SMED30006378) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PRELI/MSF1 domain-containing protein (SMED30006378) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006378

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30006378SMESG000034043.1 dd_Smed_v4_922_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006378SMESG000034043.1 dd_Smed_v4_922_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30006378SMESG000034043.1 dd_Smed_v4_922_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006378SMESG000034043.1 Contig35431newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006378SMESG000034043.1 Contig35431uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30006378SMESG000034043.1 DN289824ncbi_smed_estsPMID:16344473
Zayas et al., 2005		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
central nervous systemSMED30006378SMESG000034043.1 DN289824ncbi_smed_estsPMID:16344473
Zayas et al., 2005		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testisSMED30006378SMESG000034043.1 DN289824ncbi_smed_estsPMID:16344473
Zayas et al., 2005		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
epidermisSMED30006378SMESG000034043.1 dd_Smed_v4_922_1_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Human
Match: PRELID3B (PRELI domain containing 3B [Source:HGNC Symbol;Acc:HGNC:15892])

HSP 1 Score: 117.087 bits (292), Expect = 1.664e-31
Identity = 64/167 (38.32%), Postives = 98/167 (58.68%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVINN 525
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ RHIDP +G + +H+LL+TEW + S        +  K Y  E++ +DP  + M L S N S ++++   ERL Y   P   + T++ Q   I     + S +L+ ++ ST  +NA KGREA+EWVI+ 
Sbjct:    1 MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHIDP-SGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVEKTMELKSTNISFTNMVSVDERLIYKPHPQDPEKTVLTQEAIITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIHK 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Human
Match: PRELID3A (PRELI domain containing 3A [Source:HGNC Symbol;Acc:HGNC:24639])

HSP 1 Score: 104.76 bits (260), Expect = 4.391e-27
Identity = 58/167 (34.73%), Postives = 96/167 (57.49%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVIS-TYKANALKGREAIEWVINN 525
            +K W S + F HPWD+V+ AA  KYPN  NP+V  +D++ R +D + G + + +LL+TEW + S        S    Y  E++ +DP  ++M L S N ++++L+   ERL Y   P + + T++ Q   I     +   +L+S+++ T  +NA KG  AIEW+I +
Sbjct:    1 MKIWSSEHVFGHPWDTVIQAAMRKYPNPMNPSVLGVDVLQRRVDGR-GRLHSLRLLSTEWGLPSLVRAILGTSRTLTYIREHSVVDPVEKKMELCSTNITLTNLVSVNERLVYTPHPENPEMTVLTQEAIITVKGISLGSYLESLMANTISSNAKKGWAAIEWIIEH 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Human
Match: PRELID3A (PRELI domain containing 3A [Source:HGNC Symbol;Acc:HGNC:24639])

HSP 1 Score: 104.76 bits (260), Expect = 4.391e-27
Identity = 58/167 (34.73%), Postives = 96/167 (57.49%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVIS-TYKANALKGREAIEWVINN 525
            +K W S + F HPWD+V+ AA  KYPN  NP+V  +D++ R +D + G + + +LL+TEW + S        S    Y  E++ +DP  ++M L S N ++++L+   ERL Y   P + + T++ Q   I     +   +L+S+++ T  +NA KG  AIEW+I +
Sbjct:    1 MKIWSSEHVFGHPWDTVIQAAMRKYPNPMNPSVLGVDVLQRRVDGR-GRLHSLRLLSTEWGLPSLVRAILGTSRTLTYIREHSVVDPVEKKMELCSTNITLTNLVSVNERLVYTPHPENPEMTVLTQEAIITVKGISLGSYLESLMANTISSNAKKGWAAIEWIIEH 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Human
Match: PRELID3B (PRELI domain containing 3B [Source:HGNC Symbol;Acc:HGNC:15892])

HSP 1 Score: 95.1301 bits (235), Expect = 1.708e-23
Identity = 57/159 (35.85%), Postives = 88/159 (55.35%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVINN 525
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ RHIDP +G + +H+LL+TEW + S                    I+ S+  S ++++   ERL Y   P   + T++ Q   I     + S +L+ ++ ST  +NA KGREA+EWVI+ 
Sbjct:    1 MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHIDP-SGKLHSHRLLSTEWGLPS--------------------IVKSI--SFTNMVSVDERLIYKPHPQDPEKTVLTQEAIITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIHK 136
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Human
Match: PRELID3A (PRELI domain containing 3A [Source:HGNC Symbol;Acc:HGNC:24639])

HSP 1 Score: 89.7373 bits (221), Expect = 3.544e-21
Identity = 51/153 (33.33%), Postives = 86/153 (56.21%), Query Frame = 1 
Query:   88 SFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVIS-TYKANALKGREAI 507
            +  HPWD+V+ AA  KYPN  NP+V  +D++ R +D + G + + +LL+TEW + S        S    Y  E++ +DP  ++M L S N ++++L+   ERL Y   P + + T++ Q   I     +   +L+S+++ T  +NA KG  AI
Sbjct:   30 ACSHPWDTVIQAAMRKYPNPMNPSVLGVDVLQRRVDGR-GRLHSLRLLSTEWGLPSLVRAILGTSRTLTYIREHSVVDPVEKKMELCSTNITLTNLVSVNERLVYTPHPENPEMTVLTQEAIITVKGISLGSYLESLMANTISSNAKKGWAAI 181
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Celegans
Match: F15D3.6 (pep chromosome:WBcel235:I:11572121:11577488:-1 gene:WBGene00008856.1 transcript:F15D3.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F15D3.6)

HSP 1 Score: 85.1149 bits (209), Expect = 1.279e-19
Identity = 53/169 (31.36%), Postives = 92/169 (54.44%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPM------FSSF-GKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYI---QDPNSDQWTLMNQ----STTIEAFSGFLD-SVISTYKANALKGREAIEWVINN 525
            ++ W S + F H W++V  AA  KYPN  N ++  ID++ + ++   G + T +++ + + +       + F G  Y+ EYT IDP  +   L + N + SS L   E+L Y    +DPN    T++ Q    + T+ AF+ + + + +S Y  NA KGR+ +EWVI++
Sbjct:    1 MRIWSSEHIFDHEWETVAQAAFRKYPNPLNRSITGIDVVKQTLEA--GKILTERIIQSHFSIPSWATKLTGFSGTQYSHEYTVIDPTRKEFSLTTRNLNGSSFLRVDEKLTYTPAHEDPNK---TILKQDVIVTITLPAFADYCEKTFLSIYSQNANKGRQGVEWVIDH 164
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Fly
Match: slmo (gene:FBgn0029161 transcript:FBtr0299810)

HSP 1 Score: 95.5153 bits (236), Expect = 2.314e-23
Identity = 53/165 (32.12%), Postives = 85/165 (51.52%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEW-------PMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFL-----DSVISTYKANALKGREAIEWVIN 522
            +K W S + F HPW++V  AA  KYPN   P++   D++ R +    G++ TH+L+ ++W        +  +    +ASE + +DPE ++M+L + N +    +   E L Y   P+    TL+ Q  T+  F   L     D + ST   NA KGR+ +EWVI 
Sbjct:    1 MKIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRV--VDGVLHTHRLVQSKWYFPKWTHALIGTAKTCFASERSTVDPERKQMVLKTNNLTFCRNISVDEVLYYEPHPSDASKTLLKQEATVTVFGVPLSHYMEDLLTSTISTNAGKGRQGLEWVIG 163
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Fly
Match: slmo (gene:FBgn0029161 transcript:FBtr0343130)

HSP 1 Score: 95.5153 bits (236), Expect = 2.314e-23
Identity = 53/165 (32.12%), Postives = 85/165 (51.52%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEW-------PMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFL-----DSVISTYKANALKGREAIEWVIN 522
            +K W S + F HPW++V  AA  KYPN   P++   D++ R +    G++ TH+L+ ++W        +  +    +ASE + +DPE ++M+L + N +    +   E L Y   P+    TL+ Q  T+  F   L     D + ST   NA KGR+ +EWVI 
Sbjct:    1 MKIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRV--VDGVLHTHRLVQSKWYFPKWTHALIGTAKTCFASERSTVDPERKQMVLKTNNLTFCRNISVDEVLYYEPHPSDASKTLLKQEATVTVFGVPLSHYMEDLLTSTISTNAGKGRQGLEWVIG 163
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Fly
Match: slmo (gene:FBgn0029161 transcript:FBtr0112945)

HSP 1 Score: 95.5153 bits (236), Expect = 2.314e-23
Identity = 53/165 (32.12%), Postives = 85/165 (51.52%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEW-------PMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFL-----DSVISTYKANALKGREAIEWVIN 522
            +K W S + F HPW++V  AA  KYPN   P++   D++ R +    G++ TH+L+ ++W        +  +    +ASE + +DPE ++M+L + N +    +   E L Y   P+    TL+ Q  T+  F   L     D + ST   NA KGR+ +EWVI 
Sbjct:    1 MKIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRV--VDGVLHTHRLVQSKWYFPKWTHALIGTAKTCFASERSTVDPERKQMVLKTNNLTFCRNISVDEVLYYEPHPSDASKTLLKQEATVTVFGVPLSHYMEDLLTSTISTNAGKGRQGLEWVIG 163
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Fly
Match: slmo (gene:FBgn0029161 transcript:FBtr0079217)

HSP 1 Score: 95.5153 bits (236), Expect = 2.314e-23
Identity = 53/165 (32.12%), Postives = 85/165 (51.52%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEW-------PMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFL-----DSVISTYKANALKGREAIEWVIN 522
            +K W S + F HPW++V  AA  KYPN   P++   D++ R +    G++ TH+L+ ++W        +  +    +ASE + +DPE ++M+L + N +    +   E L Y   P+    TL+ Q  T+  F   L     D + ST   NA KGR+ +EWVI 
Sbjct:    1 MKIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRV--VDGVLHTHRLVQSKWYFPKWTHALIGTAKTCFASERSTVDPERKQMVLKTNNLTFCRNISVDEVLYYEPHPSDASKTLLKQEATVTVFGVPLSHYMEDLLTSTISTNAGKGRQGLEWVIG 163
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Fly
Match: slmo (gene:FBgn0029161 transcript:FBtr0079218)

HSP 1 Score: 95.5153 bits (236), Expect = 2.314e-23
Identity = 53/165 (32.12%), Postives = 85/165 (51.52%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEW-------PMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFL-----DSVISTYKANALKGREAIEWVIN 522
            +K W S + F HPW++V  AA  KYPN   P++   D++ R +    G++ TH+L+ ++W        +  +    +ASE + +DPE ++M+L + N +    +   E L Y   P+    TL+ Q  T+  F   L     D + ST   NA KGR+ +EWVI 
Sbjct:    1 MKIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRV--VDGVLHTHRLVQSKWYFPKWTHALIGTAKTCFASERSTVDPERKQMVLKTNNLTFCRNISVDEVLYYEPHPSDASKTLLKQEATVTVFGVPLSHYMEDLLTSTISTNAGKGRQGLEWVIG 163
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Zebrafish
Match: prelid3a (PRELI domain containing 3A [Source:ZFIN;Acc:ZDB-GENE-130530-654])

HSP 1 Score: 108.227 bits (269), Expect = 1.686e-28
Identity = 58/167 (34.73%), Postives = 100/167 (59.88%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWP--------MFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVIS-TYKANALKGREAIEWVINN 525
            +K W + + F +PW++V+ AA  KYPN  NP+V  +D++ R++D   G + +H+LL+TEW         + +S    Y  E++ +DPE ++M L S N ++++L+   ERL Y   P++ + T++ Q   I     + S +L+ +++ T  ANA KG +AIEW+I N
Sbjct:    1 MKIWSTEHIFSYPWETVIKAAMRKYPNPMNPSVVGVDVLDRNLDTH-GRLHSHRLLSTEWGLPGVVKAILGTSRTVTYVKEHSIVDPEEKKMELCSTNITLTNLISVDERLVYRPHPDNPEVTVLTQEAIITVKGVSLSSYLEGLMALTMSANARKGWDAIEWIIQN 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Zebrafish
Match: prelid3a (PRELI domain containing 3A [Source:ZFIN;Acc:ZDB-GENE-130530-654])

HSP 1 Score: 108.227 bits (269), Expect = 1.686e-28
Identity = 58/167 (34.73%), Postives = 100/167 (59.88%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWP--------MFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVIS-TYKANALKGREAIEWVINN 525
            +K W + + F +PW++V+ AA  KYPN  NP+V  +D++ R++D   G + +H+LL+TEW         + +S    Y  E++ +DPE ++M L S N ++++L+   ERL Y   P++ + T++ Q   I     + S +L+ +++ T  ANA KG +AIEW+I N
Sbjct:    1 MKIWSTEHIFSYPWETVIKAAMRKYPNPMNPSVVGVDVLDRNLDTH-GRLHSHRLLSTEWGLPGVVKAILGTSRTVTYVKEHSIVDPEEKKMELCSTNITLTNLISVDERLVYRPHPDNPEVTVLTQEAIITVKGVSLSSYLEGLMALTMSANARKGWDAIEWIIQN 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Zebrafish
Match: prelid3b (PRELI domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-031002-13])

HSP 1 Score: 101.679 bits (252), Expect = 7.155e-26
Identity = 58/165 (35.15%), Postives = 92/165 (55.76%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVI 519
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ R++D + G + + +LL+TEW + S    L        Y  E + +DP+ +   L S N + ++++   ERL Y   P   + T++ Q   I     + S +L+ ++ ST   NA KGREA+EWVI
Sbjct:    1 MKIWTSEHIFNHPWETVTKAAMQKYPNPMNPSVFGVDVLDRNVD-QQGRLHSKRLLSTEWGLPSIVRSLIGNTRTCTYIQEQSVVDPKEKTFELQSTNITFTNMVSVDERLIYRPHPEDPEKTMLTQEAIISVKGVSLSSYLEGLMASTISTNAGKGREAMEWVI 164
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Zebrafish
Match: prelid3a (PRELI domain containing 3A [Source:ZFIN;Acc:ZDB-GENE-130530-654])

HSP 1 Score: 92.8189 bits (229), Expect = 1.002e-22
Identity = 51/156 (32.69%), Postives = 91/156 (58.33%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWP--------MFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVIS-TYKANALK 492
            +K W + + F +PW++V+ AA  KYPN  NP+V  +D++ R++D   G + +H+LL+TEW         + +S    Y  E++ +DPE ++M L S N ++++L+   ERL Y   P++ + T++ Q   I     + S +L+ +++ T  ANA K
Sbjct:    1 MKIWSTEHIFSYPWETVIKAAMRKYPNPMNPSVVGVDVLDRNLDTH-GRLHSHRLLSTEWGLPGVVKAILGTSRTVTYVKEHSIVDPEEKKMELCSTNITLTNLISVDERLVYRPHPDNPEVTVLTQEAIITVKGVSLSSYLEGLMALTMSANARK 155
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Zebrafish
Match: prelid1b (PRELI domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-050522-169])

HSP 1 Score: 46.595 bits (109), Expect = 9.124e-6
Identity = 39/165 (23.64%), Postives = 76/165 (46.06%), Query Frame = 1 
Query:   67 KSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTT-----EWP--MFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVI-----STYKANALKGREAIEWVINN 525
            K +FS    K+ WD V+ A   +YPN F+ +V   D++ R +  +  ++ + +L T       W   +F     +Y  E + +D  NR +  ++ N + + L+   ER  +  + +   WT + +   I +    L   I     + +++N LK  + +E  I+N
Sbjct:    3 KYFFSETEIKNSWDLVLTAFWQRYPNPFSSHVLTEDVLFRKVTSE-NLLVSRRLFTKTNRLPRWAERIFPGRRSVYIIEDSVVDLSNRSLTTMTWNVNHAKLMRVVERCVFTGEQDRPVWTHITRQAWISSGVFGLSRPIQEFGLARFRSNQLKAMKGLEHAISN 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Xenopus
Match: lcat (lecithin-cholesterol acyltransferase [Source:Xenbase;Acc:XB-GENE-980396])

HSP 1 Score: 113.62 bits (283), Expect = 1.976e-30
Identity = 60/167 (35.93%), Postives = 98/167 (58.68%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVINN 525
            ++ W S + F HPWD+V+ AA  KYPN  NP V  +D++ R++DP+ G + + +LL TEW + S    +        Y  E++ +DP  ++M+L S N S+++L+   ERL Y   P + + T++ Q   I     + S +L+ ++ ST  +NA KG +AIEW+I N
Sbjct:    1 MRIWSSEHVFSHPWDTVIKAAMRKYPNPMNPCVVGVDVVDRNLDPQ-GRLHSQRLLCTEWGLPSLVRAILGTNRTLTYIKEHSVVDPIEKKMVLCSTNISLTNLVSVDERLVYTPHPENPEETVLTQEAIITVKGVSLSSYLEGLMASTISSNARKGWDAIEWIIQN 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Xenopus
Match: lcat (lecithin-cholesterol acyltransferase [Source:Xenbase;Acc:XB-GENE-980396])

HSP 1 Score: 105.531 bits (262), Expect = 1.849e-27
Identity = 57/156 (36.54%), Postives = 92/156 (58.97%), Query Frame = 1 
Query:   97 HPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVINN 525
            HPWD+V+ AA  KYPN  NP V  +D++ R++DP+ G + + +LL TEW + S    +        Y  E++ +DP  ++M+L S N S+++L+   ERL Y   P + + T++ Q   I     + S +L+ ++ ST  +NA KG +AIEW+I N
Sbjct:    7 HPWDTVIKAAMRKYPNPMNPCVVGVDVVDRNLDPQ-GRLHSQRLLCTEWGLPSLVRAILGTNRTLTYIKEHSVVDPIEKKMVLCSTNISLTNLVSVDERLVYTPHPENPEETVLTQEAIITVKGVSLSSYLEGLMASTISSNARKGWDAIEWIIQN 161
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Xenopus
Match: lcat (lecithin-cholesterol acyltransferase [Source:Xenbase;Acc:XB-GENE-980396])

HSP 1 Score: 105.145 bits (261), Expect = 1.587e-26
Identity = 58/159 (36.48%), Postives = 93/159 (58.49%), Query Frame = 1 
Query:   88 SFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVINN 525
            S  HPWD+V+ AA  KYPN  NP V  +D++ R++DP+ G + + +LL TEW + S    +        Y  E++ +DP  ++M+L S N S+++L+   ERL Y   P + + T++ Q   I     + S +L+ ++ ST  +NA KG +AIEW+I N
Sbjct:   74 STCHPWDTVIKAAMRKYPNPMNPCVVGVDVVDRNLDPQ-GRLHSQRLLCTEWGLPSLVRAILGTNRTLTYIKEHSVVDPIEKKMVLCSTNISLTNLVSVDERLVYTPHPENPEETVLTQEAIITVKGVSLSSYLEGLMASTISSNARKGWDAIEWIIQN 231
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Xenopus
Match: jak3 (Janus kinase 3 (a protein tyrosine kinase, leukocyte) [Source:Xenbase;Acc:XB-GENE-5904698])

HSP 1 Score: 47.3654 bits (111), Expect = 8.238e-6
Identity = 46/215 (21.40%), Postives = 97/215 (45.12%), Query Frame = 1 
Query:   73 WFSNYS-FKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLL--TTEWPMFSS-------FGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEA-FSGFLDSV----ISTYKANALKGREAIEWVINNRLPLLPKIPECQKIVPAHPENDIDQFISHVETCWDDISRDVTKAKDEFI 672
            +FS ++  K+ WD V  A   +YPN ++ +V   DI+ R + P   ++ T +LL  T   P ++           +Y  E + IDP ++ M   + N + +S++  +ER  Y ++  +  WT + +   + +   G   ++    ++ +K+N  K  +  E+++      +P     +    A  E   +  ++  E   D  S+  T  K +++
Sbjct:    4 YFSGFNILKNSWDQVSAAFWQRYPNPYSKHVLSEDILYREVTPDHKLL-TRRLLTKTNRLPRWAERIFPANVAHAVYVVEDSIIDPFSKTMTTYTWNINHASIMSVEERCVYCENSENSNWTEIKREAWVSSKVFGLTRAIQEFGLARFKSNVTKAMKGFEFILGKMQGDVPHRTLVETAKEA-TEKAKETALAAKEKAKDLASKAATTKKQQYV 216
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Mouse
Match: Prelid3b (PRELI domain containing 3B [Source:MGI Symbol;Acc:MGI:1913640])

HSP 1 Score: 117.472 bits (293), Expect = 9.586e-32
Identity = 66/169 (39.05%), Postives = 100/169 (59.17%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEY---IQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVIN 522
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ RH+DP +G + +H+LL+TEW + S        +  K Y  E++ +DP  R M L S N S ++++   ERL Y   +QDP     T++ Q   I     + S +L+ ++ ST  +NA KGREA+EWVI+
Sbjct:    1 MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHVDP-SGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVTRTMELKSTNISFTNMVSVDERLTYKPHLQDPEK---TVLTQEALITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIH 165
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Mouse
Match: Prelid3a (PRELI domain containing 3A [Source:MGI Symbol;Acc:MGI:2442865])

HSP 1 Score: 101.679 bits (252), Expect = 4.783e-26
Identity = 57/165 (34.55%), Postives = 91/165 (55.15%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVI 519
            +K W S + F HPWD+V+ AA  KYPN  NP V  +D++ R +D   G + + +LL+TEW +      +        Y  E + +DP  R+M L S N ++++L+   ERL Y   P + + T++ Q   I     +   +L+S++ +T  +NA KG  AIEW+I
Sbjct:    1 MKIWSSEHVFGHPWDTVIKAAMRKYPNPMNPCVVGVDVLERSVD-GCGRLHSLRLLSTEWGLPGLVRAILGANRTLTYIKERSVVDPAARKMELCSTNITLTNLVSVNERLVYTPHPENPEKTVLTQEAIITVKGISLGSYLESLMATTISSNAKKGWAAIEWII 164
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Mouse
Match: Prelid3a (PRELI domain containing 3A [Source:MGI Symbol;Acc:MGI:2442865])

HSP 1 Score: 69.707 bits (169), Expect = 8.801e-14
Identity = 40/132 (30.30%), Postives = 69/132 (52.27%), Query Frame = 1 
Query:  112 VVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVIST 471
            V+ AA  KYPN  NP V  +D++ R +D   G + + +LL+TEW +      +        Y  E + +DP  R+M L S N ++++L+   ERL Y   P + + T++ Q   I     +   +L+S+++T
Sbjct:    2 VIKAAMRKYPNPMNPCVVGVDVLERSVD-GCGRLHSLRLLSTEWGLPGLVRAILGANRTLTYIKERSVVDPAARKMELCSTNITLTNLVSVNERLVYTPHPENPEKTVLTQEAIITVKGISLGSYLESLMAT 132
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Mouse
Match: Prelid1 (PRELI domain containing 1 [Source:MGI Symbol;Acc:MGI:1913744])

HSP 1 Score: 48.521 bits (114), Expect = 2.354e-6
Identity = 38/166 (22.89%), Postives = 77/166 (46.39%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL---------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTI-EAFSGFLDSV----ISTYKANALKGREAIEWVI 519
            +K +      +  WD V  A   +YPN ++ +V   DI+ R + P   ++ + +LLT    M     +L         Y  E + +DP+N+ M   + N + + L+V +ER  Y  + ++  WT + +   +  +  G   +V    ++ +K+N  K  +  E+++
Sbjct:    2 VKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLL-SRRLLTKTNRMPRWAERLFPANVAHSVYILEDSIVDPQNQTMTTFTWNINHARLMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFGVSRAVQEFGLARFKSNVTKTMKGFEYIL 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6P9U4|PLD3B_RAT (PRELI domain containing protein 3B OS=Rattus norvegicus OX=10116 GN=Prelid3b PE=1 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 2.776e-31
Identity = 64/166 (38.55%), Postives = 98/166 (59.04%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVIN 522
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ RH+DP +G + +H+LL+TEW + S        +  K Y  E++ +DP  R M L S N S ++++   ERL Y   P   + T++ Q   I     + S +L+ ++ ST  +NA KGREA+EWVI+
Sbjct:    1 MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHVDP-SGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPIRRTMELKSTNISFTNMVSVDERLTYKPHPQDPEKTVLTQEALITVKGVSLSSYLEGLMASTISSNANKGREAMEWVIH 165
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9CYY7|PLD3B_MOUSE (PRELI domain containing protein 3B OS=Mus musculus OX=10090 GN=Prelid3b PE=1 SV=2)

HSP 1 Score: 117.472 bits (293), Expect = 6.705e-31
Identity = 66/169 (39.05%), Postives = 100/169 (59.17%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEY---IQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVIN 522
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ RH+DP +G + +H+LL+TEW + S        +  K Y  E++ +DP  R M L S N S ++++   ERL Y   +QDP     T++ Q   I     + S +L+ ++ ST  +NA KGREA+EWVI+
Sbjct:    1 MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHVDP-SGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVTRTMELKSTNISFTNMVSVDERLTYKPHLQDPEK---TVLTQEALITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIH 165
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Y3B1|PLD3B_HUMAN (PRELI domain containing protein 3B OS=Homo sapiens OX=9606 GN=PRELID3B PE=1 SV=2)

HSP 1 Score: 117.087 bits (292), Expect = 7.990e-31
Identity = 64/167 (38.32%), Postives = 98/167 (58.68%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVINN 525
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ RHIDP +G + +H+LL+TEW + S        +  K Y  E++ +DP  + M L S N S ++++   ERL Y   P   + T++ Q   I     + S +L+ ++ ST  +NA KGREA+EWVI+ 
Sbjct:    1 MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHIDP-SGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVEKTMELKSTNISFTNMVSVDERLIYKPHPQDPEKTVLTQEAIITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIHK 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4R5S9|PLD3B_MACFA (PRELI domain containing protein 3B OS=Macaca fascicularis OX=9541 GN=PRELID3B PE=2 SV=1)

HSP 1 Score: 116.316 bits (290), Expect = 1.543e-30
Identity = 64/167 (38.32%), Postives = 97/167 (58.08%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVINN 525
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ RHIDP +G + +H+LL+TEW + S        +  K Y  E++ +DP  + M L S N S ++++   ERL Y   P     T++ Q   I     + S +L+ ++ ST  +NA KGREA+EWVI+ 
Sbjct:    1 MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHIDP-SGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVEKTMELKSTNISFTNMVSVDERLIYKPHPQDPDKTILTQEAIITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIHK 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6TMK8|PLD3B_CRIGR (PRELI domain containing protein 3B OS=Cricetulus griseus OX=10029 GN=PRELID3B PE=2 SV=1)

HSP 1 Score: 116.316 bits (290), Expect = 1.819e-30
Identity = 63/166 (37.95%), Postives = 97/166 (58.43%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFS--------SFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVIN 522
            +K W S + F HPW+ V  AA  KYPN  NP+V  +D++ RH+DP +G + +H+LL+TEW + S        +  K Y  E++ +DP  + M L S N S ++++   ERL Y   P   + T++ Q   I     + S +L+ ++ ST  +NA KGREA+EWVI+
Sbjct:    1 MKIWTSEHVFDHPWEMVTTAAMQKYPNPMNPSVVGVDVLDRHVDP-SGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVKKTMELKSTNISFTNMVSVDERLTYKPHPQDPEKTVLTQEAIITVKGVSLSSYLEGLMASTISSNANKGREAMEWVIH 165
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. TrEMBL
Match: A0A0R3SK61 (PRELI/MSF1 domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS5324 PE=4 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 1.451e-40
Identity = 72/153 (47.06%), Postives = 101/153 (66.01%), Query Frame = 1 
Query:   73 WFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVISTYKANALKGREAIEWVINNRL 531
            W   +  K PW+ V+ AA  KYPN FNPNV  IDIISR +D +TG+++T KL+ + WPMFS+ G+L A E T +DP N+RM+L S N  + S+L A ERLEY   P++ +WTL+    +++AFS    + +S  +  A  GREA+ WVI NR+
Sbjct:    8 WKGEFVIKKPWNDVMRAAQVKYPNPFNPNVLSIDIISRKVDSETGVLYTTKLINSSWPMFSNAGELRAIERTEVDPANQRMLLESNNIDMRSVLKAHERLEYEVHPDNSEWTLIRHQISVDAFSFIAYAALSASQKAAKSGREALNWVIENRV 160
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. TrEMBL
Match: A0A0R3W3K2 (PRELI/MSF1 domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS4502 PE=4 SV=1)

HSP 1 Score: 149.443 bits (376), Expect = 1.249e-39
Identity = 72/153 (47.06%), Postives = 97/153 (63.40%), Query Frame = 1 
Query:   73 WFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVISTYKANALKGREAIEWVINNRL 531
            W   +  K PWD V+ AA  KYPN FNPNV  IDIISR ID +TG++ T KL+ + WPMFSS G+L A E T +DP  R M+L S N  +  +L A ERLEY   P++ +WTL+    +++AF     + +S  +  A  GREA++WVI NR+
Sbjct:    8 WSGEFVIKKPWDDVMRAAQLKYPNPFNPNVLTIDIISRSIDKETGVLCTTKLINSSWPMFSSVGELRAVERTEVDPRRRYMLLESNNVDMRGVLKANERLEYEVHPDNPEWTLIRHKVSVDAFRFIAYAALSASENTARSGREALKWVIENRV 160
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. TrEMBL
Match: A0A068YK03 (Protein slowmo OS=Echinococcus multilocularis OX=6211 GN=EmuJ_001032500 PE=4 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 2.970e-38
Identity = 76/185 (41.08%), Postives = 109/185 (58.92%), Query Frame = 1 
Query:   73 WFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVISTYKANALKGREAIEWVINNRLP-LLPKIPECQKI-VPAHPENDIDQFISHVET 621
            W   +  K PWD V+ AA  KYPN FNPNV  ID+ISR+ID +TG++ T KL+ + WPMFSS G L A E T +DP+ + M+L S N  +  +L A ERLEY   P++ +WTL+    +++AF     + +S  +  A  GREA++WVI NR+   + + P    +  P+     +  F SH  T
Sbjct:    8 WTGEFVIKKPWDDVMRAAQLKYPNPFNPNVLTIDVISRNIDRETGVLRTTKLINSSWPMFSSVGDLRAVERTEVDPQRQYMLLESNNVDMRGVLKANERLEYEVHPDNPEWTLVRHKISVDAFRFIAYAALSASEKTARSGREALKWVIENRIDHFMVRAPSKTDVSAPSSYLTPVSSFFSHGAT 192
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. TrEMBL
Match: W6UM86 (PRELI/MSF1 domain-containing protein OS=Echinococcus granulosus OX=6210 GN=EGR_02920 PE=4 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 2.524e-37
Identity = 75/185 (40.54%), Postives = 106/185 (57.30%), Query Frame = 1 
Query:   73 WFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVISTYKANALKGREAIEWVINNRLP-LLPKIPECQKI-VPAHPENDIDQFISHVET 621
            W   +  K PW  V+ AA  KYPN FNPNV  ID+ISR+ID +TG++ T KL+ + WPMFSS G L A E T +DP  + M+L S N  +  +L A ERLEY   P + +WTL+    +++AF     + +S  +  A  GREA++WVI NR+   + + P    +  P+     +  F SH  T
Sbjct:    8 WTGEFVIKKPWADVMRAAQLKYPNPFNPNVLTIDVISRNIDRETGVLRTTKLINSSWPMFSSVGDLRAVERTEVDPRRQYMLLESNNVDMRGVLKANERLEYEVHPGNPEWTLVRHKISVDAFRFIAYAALSASEKTARSGREALKWVIENRIDHFMVRAPSKTDVSAPSSYLTPVSSFFSHGAT 192
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. TrEMBL
Match: A0A068WBU5 (Protein slowmo OS=Echinococcus granulosus OX=6210 GN=EgrG_001032500 PE=4 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 3.293e-37
Identity = 75/185 (40.54%), Postives = 106/185 (57.30%), Query Frame = 1 
Query:   73 WFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVISTYKANALKGREAIEWVINNRLP-LLPKIPECQKI-VPAHPENDIDQFISHVET 621
            W   +  K PW  V+ AA  KYPN FNPNV  ID+ISR+ID +TG++ T KL+ + WPMFSS G L A E T +DP  + M+L S N  +  +L A ERLEY   P + +WTL+    +++AF     + +S  +  A  GREA++WVI NR+   + + P    +  P+     +  F SH  T
Sbjct:    8 WTGEFVIKKPWADVMRAAQLKYPNPFNPNVLTIDVISRNIDRETGVLRTTKLINSSWPMFSSVGDLRAVERTEVDPRRQYMLLESNNVDMRGVLKANERLEYEVHPGNPEWTLVRHKISVDAFRFIAYAALSASEKTARSGREALKWVIENRIDHFMVRAPSKTDVSAPSSYLTPVSSFFSHGAT 192
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Cavefish
Match: prelid3a (PRELI domain containing 3A [Source:NCBI gene;Acc:103027209])

HSP 1 Score: 106.686 bits (265), Expect = 5.005e-28
Identity = 57/167 (34.13%), Postives = 100/167 (59.88%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWP--------MFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVIS-TYKANALKGREAIEWVINN 525
            +K W + + F +PW++V+ AA  KYPN  NP+V  +D++ R++D K G + +H+LL+TEW         + +S    Y  E++ +DP+ ++M L S N ++++L+   ERL Y   P + + T++ Q   I     + S +L+ +++ +  ANA KG +AIEW+I N
Sbjct:    1 MKIWSTEHIFSYPWETVIKAAMRKYPNPMNPSVVGVDVLDRNLD-KNGRLHSHRLLSTEWGLPGVVRAILGTSRTLTYIKEHSIVDPKEKKMELCSTNITLTNLVSVDERLVYRPHPENPEVTILTQEAIITVKGVSLSSYLEGLMAMSMSANARKGWDAIEWIIKN 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Cavefish
Match: prelid3b (PRELI domain containing 3B [Source:NCBI gene;Acc:103030743])

HSP 1 Score: 99.7525 bits (247), Expect = 3.609e-25
Identity = 57/165 (34.55%), Postives = 91/165 (55.15%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVI 519
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ R +D + G + + +LL+TEW + S    +        Y  E + +DP+ +   L S N + ++++   ERL Y   P   + T++ Q   I     + S +L+ ++ ST   NA KGREA+EWVI
Sbjct:    1 MKIWTSEHIFNHPWETVTKAAMQKYPNPMNPSVFGVDVLDRSVDHQ-GRLHSKRLLSTEWGLPSIVKAIIGNTRTCTYVQEQSMVDPKEKTFELQSSNITFTNMVSVDERLTYRPHPQDPEKTVLTQEAIISVKGVSLSSYLEGLMASTISTNAGKGREAMEWVI 164
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Cavefish
Match: prelid3b (PRELI domain containing 3B [Source:NCBI gene;Acc:103030743])

HSP 1 Score: 92.0485 bits (227), Expect = 3.688e-22
Identity = 53/154 (34.42%), Postives = 85/154 (55.19%), Query Frame = 1 
Query:   97 HPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVI 519
            HPW++V  AA  KYPN  NP+V  +D++ R +D + G + + +LL+TEW + S    +        Y  E + +DP+ +   L S N + ++++   ERL Y   P   + T++ Q   I     + S +L+ ++ ST   NA KGREA+EWVI
Sbjct:   16 HPWETVTKAAMQKYPNPMNPSVFGVDVLDRSVDHQ-GRLHSKRLLSTEWGLPSIVKAIIGNTRTCTYVQEQSMVDPKEKTFELQSSNITFTNMVSVDERLTYRPHPQDPEKTVLTQEAIISVKGVSLSSYLEGLMASTISTNAGKGREAMEWVI 168
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Cavefish
Match: prelid1a (PRELI domain containing 1 [Source:NCBI gene;Acc:103036730])

HSP 1 Score: 51.9878 bits (123), Expect = 9.729e-8
Identity = 43/164 (26.22%), Postives = 81/164 (49.39%), Query Frame = 1 
Query:   73 WFSNYSF-KHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLT--TEWPMFSS-------FGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTI-EAFSGFLDSV----ISTYKANALKGREAIEWVI 519
            +FS   F K  WD V  A   +YPN ++ +V   DI+ R + P   ++ + +LLT  +  P ++          K Y  E + +DP NR M+ ++ N S + ++  +ER  Y  +P++  WT + +   I  +  G   +V    ++ +K++  K  +  E+V+
Sbjct:    4 YFSCVGFLKGTWDQVFAAFWQRYPNPYSNHVLTEDIVFREVTPDNRLL-SRRLLTKTSRAPRWAEKFLPSHMARKAYIIEDSVVDPNNRTMVTLTWNISHARVMSVEERCVYRVNPDNSNWTEIKREAWISSSLYGLSRAVQEFGLARFKSSVTKTMKGFEYVL 166
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Cavefish
Match: prelid1b (PRELI domain-containing protein 1, mitochondrial-like [Source:NCBI gene;Acc:103043151])

HSP 1 Score: 49.6766 bits (117), Expect = 5.857e-7
Identity = 40/162 (24.69%), Postives = 75/162 (46.30%), Query Frame = 1 
Query:   67 KSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTT-----EWPMFSSFGKLYASEY----TAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVI-----STYKANALKGREAIE 510
            K +F+    +  W++V+ A   +YPN ++ +V   D++ R + P    + + +LLT       W      G L  S Y    + +DP NRR+  ++ N + S+L+   ER  +  + +   WT + +   I +    L   I     S +K+N +K  + +E
Sbjct:    3 KYFFNETDIRSAWENVLTAFWQRYPNPYSTHVLTEDVVFREVTPD-NCLLSRRLLTKTNRLPRWAERIFPGNLARSVYIVEDSIVDPNNRRLTTLTWNLNHSTLMTVVERCVFHGERDRPVWTRLTREAWISSGVFGLSRPIQEFGLSRFKSNQIKAMKGLE 163
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Yeast
Match: UPS2 (Mitochondrial intermembrane space protein; involved in phospholipid metabolism; forms complex with Mdm35p that transfers phosphatidylserine from outer membrane to inner membrane for phosphatidylethanolamine synthesis; null mutant has defects in mitochondrial morphology; similar to Ups1p, Ups3p and to human PRELI; UPS2 has a paralog, UPS3, that arose from the whole genome duplication [Source:SGD;Acc:S000004158])

HSP 1 Score: 58.9214 bits (141), Expect = 7.061e-11
Identity = 42/167 (25.15%), Postives = 76/167 (45.51%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTT-----EWPMFSSFGK--LYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDP-NSDQWTLMNQSTTIEAFSGFL-------DSVISTYKANALKGREAIEWVI 519
            +K + ++Y F +PWD V  A   KYPN  + +V  +D++ R +  +  ++ T +L+T      +W M    G    +  E + +D   + + + S N ++ +LL   E + Y   P +S   TL  Q   I A+           D  +  +  NA KG+   + V+
Sbjct:    1 MKLFQNSYDFNYPWDQVTAANWKKYPNEISTHVIAVDVLRRELKDQGKVLVTERLITVKQGVPKWIMMMLGGTNMSHVREVSVVDLNKKSLTMRSCNLTMCNLLKVYETVTYSPHPDDSANKTLFQQEAQITAYGSIRKLCNKMEDWSVQRFCENAKKGKMGFDAVL 167
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Yeast
Match: UPS3 (Mitochondrial protein of unknown function; similar to Ups1p and Ups2p which are involved in regulation of mitochondrial cardiolipin and phosphatidylethanolamine levels; null is viable but interacts synthetically with ups1 and ups2 mutations; UPS3 has a paralog, UPS2, that arose from the whole genome duplication [Source:SGD;Acc:S000002593])

HSP 1 Score: 55.8398 bits (133), Expect = 4.132e-10
Identity = 39/167 (23.35%), Postives = 76/167 (45.51%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTE-----WP--MFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDP-NSDQWTLMNQSTTI------EAFSGFLDS-VISTYKANALKGREAIEWVI 519
            +KS+  +Y F +PW+ V  A   KYPN  + +V  +D++ R +     ++ T +L+T       W   +  +    Y  E + +D  +R + + S N +   +L   E + Y+  P N    TL  Q          + FS  +++  +  +  NA+KG+   + ++
Sbjct:    1 MKSFQKSYEFDYPWEKVTTANWMKYPNKISTHVIAVDVLRRELKEHGDVLLTERLITIRQNTPHWMSILVGNTNLAYVREVSTVDRRDRSLTMRSCNMTFPHILKCYETVRYVPHPKNPSNVTLFKQDAKFLSGVPTKTFSEKVENWGVKRFSDNAVKGKVGFDSIL 167
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Nematostella
Match: EDO37602 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFC7])

HSP 1 Score: 50.8322 bits (120), Expect = 6.482e-8
Identity = 37/155 (23.87%), Postives = 72/155 (46.45%), Query Frame = 1 
Query:   91 FKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYAS-------EYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLM-NQSTTIEAFSGFLDSV----ISTYKANALKGREAIEWVI 519
             ++ WD V  A   +YPN ++ +V   D++SR ++     + T +LLT        +G+ + +       E + +DP  + +   + N +  +L+V +E+  Y   P + +WT    QS       GF  ++    I  YK N  K  + +E+++
Sbjct:    2 LRYAWDQVSAAYWRRYPNPWSKHVLSEDVVSRVVEEDK--LKTKRLLTKT-NRLPRWGERFVNSRVACIIEESVVDPVAKTLTTYTRNITFKTLMVVEEKCVYTVSPQNKEWTTCERQSWVTSGVYGFARAIEAFGIERYKNNVKKTSKGLEYIL 153
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Medaka
Match: PRELID3B (PRELI domain containing protein 3B [Source:NCBI gene;Acc:101164398])

HSP 1 Score: 103.605 bits (257), Expect = 1.384e-26
Identity = 58/165 (35.15%), Postives = 90/165 (54.55%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVIS-TYKANALKGREAIEWVI 519
            +K W S + F HPW++V  AA  KYPN  NP V  +D++ R +DP  G + + +LL+TEW + +    +        Y  E++ +DP  R   L S N S ++L+   E+L Y   P   + T++ Q   I     + S +L+ +++ T   NA KGREA+EWVI
Sbjct:    1 MKIWASEHIFNHPWETVTKAAMQKYPNPMNPGVFGVDVLDRKVDPD-GRLHSTRLLSTEWGLPAIAKSIIGVTRTCTYVQEHSVVDPNQRTFELQSTNISFTNLVSVDEKLTYKPHPQDPEKTVLTQEALISVKGVSLSNYLEGLMANTISVNASKGREAMEWVI 164
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Medaka
Match: prelid3b (PRELI domain containing protein 3B [Source:NCBI gene;Acc:101165878])

HSP 1 Score: 103.219 bits (256), Expect = 1.857e-26
Identity = 59/165 (35.76%), Postives = 91/165 (55.15%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVI 519
            +K W S + F HPW++V  AA  KYPN  NP+V  +D++ R +D + G + + +LL+TEW + S    L        Y  E + +DP+ +   L S N + ++++   ERL Y   P   + T++ Q   I     + S +L+ V+ ST   NA KGREA+EWVI
Sbjct:    1 MKVWTSEHVFNHPWETVTKAAMQKYPNPMNPSVIGVDVLDRRVDHR-GRLHSKRLLSTEWGLPSIVKSLIGSSRTYTYIQENSVVDPKEKTFELQSANITFTNMVSVDERLTYKPHPEDPEKTILTQEAIISVKGVSLSSYLEGVMASTISNNAGKGREAMEWVI 164
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Medaka
Match: prelid3b (PRELI domain containing protein 3B [Source:NCBI gene;Acc:101165878])

HSP 1 Score: 94.7449 bits (234), Expect = 2.047e-23
Identity = 55/154 (35.71%), Postives = 85/154 (55.19%), Query Frame = 1 
Query:   97 HPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKL--------YASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDSVI-STYKANALKGREAIEWVI 519
            HPW++V  AA  KYPN  NP+V  +D++ R +D + G + + +LL+TEW + S    L        Y  E + +DP+ +   L S N + ++++   ERL Y   P   + T++ Q   I     + S +L+ V+ ST   NA KGREA+EWVI
Sbjct:    4 HPWETVTKAAMQKYPNPMNPSVIGVDVLDRRVDHR-GRLHSKRLLSTEWGLPSIVKSLIGSSRTYTYIQENSVVDPKEKTFELQSANITFTNMVSVDERLTYKPHPEDPEKTILTQEAIISVKGVSLSSYLEGVMASTISNNAGKGREAMEWVI 156
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Medaka
Match: prelid3a (PRELI domain containing 3A [Source:NCBI gene;Acc:101168813])

HSP 1 Score: 90.8929 bits (224), Expect = 4.276e-22
Identity = 49/156 (31.41%), Postives = 89/156 (57.05%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWP--------MFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIE----AFSGFLDS-VISTYKANALK 492
            +K W + + F +PW++V+ AA  KYPN  NPNV  +D++ R +D + G + +H+LL+TEW         + ++  + Y  E++ +DP+ ++M L S N ++++L+   ERL Y   P +   T++ Q   I     + S +L+  ++ +  ANA K
Sbjct:    1 MKIWSTEHVFSYPWETVIKAAMRKYPNPMNPNVVGVDVLDRTLDAE-GRLHSHRLLSTEWGLPGIVRAILGTNQTQTYVKEHSIVDPDEKKMELCSTNITLTNLISVDERLLYRPHPENPGVTVLTQEAIITVKGVSLSSYLEGMMVRSMSANARK 155
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Medaka
Match: prelid3a (PRELI domain containing 3A [Source:NCBI gene;Acc:101168813])

HSP 1 Score: 82.0333 bits (201), Expect = 6.866e-19
Identity = 40/119 (33.61%), Postives = 72/119 (60.50%), Query Frame = 1 
Query:   64 IKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWP--------MFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNS 396
            +K W + + F +PW++V+ AA  KYPN  NPNV  +D++ R +D + G + +H+LL+TEW         + ++  + Y  E++ +DP+ ++M L S N ++++L+   ERL Y   P +
Sbjct:    2 MKIWSTEHVFSYPWETVIKAAMRKYPNPMNPNVVGVDVLDRTLDAE-GRLHSHRLLSTEWGLPGIVRAILGTNQTQTYVKEHSIVDPDEKKMELCSTNITLTNLISVDERLLYRPHPEN 119
[Close]
BLAST of PRELI/MSF1 domain-containing protein vs. Planmine SMEST
Match: SMESG000034043.1 (SMESG000034043.1)

HSP 1 Score: 484.182 bits (1245), Expect = 9.890e-176
Identity = 233/233 (100.00%), Postives = 233/233 (100.00%), Query Frame = 1 
Query:   52 MFNGIKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVISTYKANALKGREAIEWVINNRLPLLPKIPECQKIVPAHPENDIDQFISHVETCWDDISRDVTKAKDEFISRGAVIKENFTNLFFENIYVWGNQFS 750
            MFNGIKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVISTYKANALKGREAIEWVINNRLPLLPKIPECQKIVPAHPENDIDQFISHVETCWDDISRDVTKAKDEFISRGAVIKENFTNLFFENIYVWGNQFS
Sbjct:    1 MFNGIKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPKTGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSLLVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVISTYKANALKGREAIEWVINNRLPLLPKIPECQKIVPAHPENDIDQFISHVETCWDDISRDVTKAKDEFISRGAVIKENFTNLFFENIYVWGNQFS 233
The following BLAST results are available for this feature:
BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRELID3B1.664e-3138.32PRELI domain containing 3B [Source:HGNC Symbol;Acc... [more]
PRELID3A4.391e-2734.73PRELI domain containing 3A [Source:HGNC Symbol;Acc... [more]
PRELID3A4.391e-2734.73PRELI domain containing 3A [Source:HGNC Symbol;Acc... [more]
PRELID3B1.708e-2335.85PRELI domain containing 3B [Source:HGNC Symbol;Acc... [more]
PRELID3A3.544e-2133.33PRELI domain containing 3A [Source:HGNC Symbol;Acc... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
F15D3.61.279e-1931.36pep chromosome:WBcel235:I:11572121:11577488:-1 gen... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slmo2.314e-2332.12gene:FBgn0029161 transcript:FBtr0299810[more]
slmo2.314e-2332.12gene:FBgn0029161 transcript:FBtr0343130[more]
slmo2.314e-2332.12gene:FBgn0029161 transcript:FBtr0112945[more]
slmo2.314e-2332.12gene:FBgn0029161 transcript:FBtr0079217[more]
slmo2.314e-2332.12gene:FBgn0029161 transcript:FBtr0079218[more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prelid3a1.686e-2834.73PRELI domain containing 3A [Source:ZFIN;Acc:ZDB-GE... [more]
prelid3a1.686e-2834.73PRELI domain containing 3A [Source:ZFIN;Acc:ZDB-GE... [more]
prelid3b7.155e-2635.15PRELI domain containing 3 [Source:ZFIN;Acc:ZDB-GEN... [more]
prelid3a1.002e-2232.69PRELI domain containing 3A [Source:ZFIN;Acc:ZDB-GE... [more]
prelid1b9.124e-623.64PRELI domain containing 1b [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
lcat1.976e-3035.93lecithin-cholesterol acyltransferase [Source:Xenba... [more]
lcat1.849e-2736.54lecithin-cholesterol acyltransferase [Source:Xenba... [more]
lcat1.587e-2636.48lecithin-cholesterol acyltransferase [Source:Xenba... [more]
jak38.238e-621.40Janus kinase 3 (a protein tyrosine kinase, leukocy... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Prelid3b9.586e-3239.05PRELI domain containing 3B [Source:MGI Symbol;Acc:... [more]
Prelid3a4.783e-2634.55PRELI domain containing 3A [Source:MGI Symbol;Acc:... [more]
Prelid3a8.801e-1430.30PRELI domain containing 3A [Source:MGI Symbol;Acc:... [more]
Prelid12.354e-622.89PRELI domain containing 1 [Source:MGI Symbol;Acc:M... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6P9U4|PLD3B_RAT2.776e-3138.55PRELI domain containing protein 3B OS=Rattus norve... [more]
sp|Q9CYY7|PLD3B_MOUSE6.705e-3139.05PRELI domain containing protein 3B OS=Mus musculus... [more]
sp|Q9Y3B1|PLD3B_HUMAN7.990e-3138.32PRELI domain containing protein 3B OS=Homo sapiens... [more]
sp|Q4R5S9|PLD3B_MACFA1.543e-3038.32PRELI domain containing protein 3B OS=Macaca fasci... [more]
sp|Q6TMK8|PLD3B_CRIGR1.819e-3037.95PRELI domain containing protein 3B OS=Cricetulus g... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3SK611.451e-4047.06PRELI/MSF1 domain-containing protein OS=Hymenolepi... [more]
A0A0R3W3K21.249e-3947.06PRELI/MSF1 domain-containing protein OS=Taenia asi... [more]
A0A068YK032.970e-3841.08Protein slowmo OS=Echinococcus multilocularis OX=6... [more]
W6UM862.524e-3740.54PRELI/MSF1 domain-containing protein OS=Echinococc... [more]
A0A068WBU53.293e-3740.54Protein slowmo OS=Echinococcus granulosus OX=6210 ... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prelid3a5.005e-2834.13PRELI domain containing 3A [Source:NCBI gene;Acc:1... [more]
prelid3b3.609e-2534.55PRELI domain containing 3B [Source:NCBI gene;Acc:1... [more]
prelid3b3.688e-2234.42PRELI domain containing 3B [Source:NCBI gene;Acc:1... [more]
prelid1a9.729e-826.22PRELI domain containing 1 [Source:NCBI gene;Acc:10... [more]
prelid1b5.857e-724.69PRELI domain-containing protein 1, mitochondrial-l... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
UPS27.061e-1125.15Mitochondrial intermembrane space protein; involve... [more]
UPS34.132e-1023.35Mitochondrial protein of unknown function; similar... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO376026.482e-823.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRELID3B1.384e-2635.15PRELI domain containing protein 3B [Source:NCBI ge... [more]
prelid3b1.857e-2635.76PRELI domain containing protein 3B [Source:NCBI ge... [more]
prelid3b2.047e-2335.71PRELI domain containing protein 3B [Source:NCBI ge... [more]
prelid3a4.276e-2231.41PRELI domain containing 3A [Source:NCBI gene;Acc:1... [more]
prelid3a6.866e-1933.61PRELI domain containing 3A [Source:NCBI gene;Acc:1... [more]
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BLAST of PRELI/MSF1 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000034043.19.890e-176100.00SMESG000034043.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006378 ID=SMED30006378|Name=PRELI/MSF1 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=844bp
CTAACTTAAGTAATGTTACATTTGAAATTTTAGTTTTATTAAAATTGCAG
CATGTTTAATGGTATAAAAAGCTGGTTTTCGAATTATTCATTTAAACATC
CTTGGGATTCAGTTGTGTATGCTGCTTCATATAAATATCCAAATAATTTT
AACCCTAATGTTAAACATATTGATATAATTTCGAGACATATTGATCCTAA
AACTGGCATTATGTTTACACATAAATTGTTGACCACGGAATGGCCAATGT
TTAGTAGTTTTGGTAAGCTTTATGCTAGTGAATACACCGCTATAGACCCC
GAAAATCGTCGAATGATTTTAGTTTCTGTTAATCATAGTATATCAAGTTT
ATTAGTCGCAAAAGAGAGGTTAGAATATATTCAAGATCCAAATTCAGATC
AATGGACATTAATGAATCAGAGTACAACCATAGAAGCCTTTTCAGGGTTT
TTAGATAGTGTAATAAGTACATATAAAGCCAATGCTTTGAAAGGTAGAGA
AGCGATAGAGTGGGTCATCAATAATCGACTGCCTTTACTACCGAAAATTC
CAGAATGTCAAAAAATAGTTCCTGCTCATCCAGAAAACGATATCGATCAG
TTCATATCTCATGTGGAAACGTGCTGGGATGACATATCTCGCGATGTCAC
AAAAGCTAAAGATGAGTTTATTAGTCGCGGTGCTGTTATAAAGGAAAATT
TTACAAACCTTTTTTTCGAGAATATTTACGTGTGGGGAAATCAATTTTCT
TAATTGTTTCCCAGTTCACATTCTACCGAAATATATCAATAAATTTCTAG
TTTTCACTAAATATTAAATGAGAAATGTTAATGTTGGTTTTTAC
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protein sequence of SMED30006378-orf-1

>SMED30006378-orf-1 ID=SMED30006378-orf-1|Name=SMED30006378-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=234bp
MFNGIKSWFSNYSFKHPWDSVVYAASYKYPNNFNPNVKHIDIISRHIDPK
TGIMFTHKLLTTEWPMFSSFGKLYASEYTAIDPENRRMILVSVNHSISSL
LVAKERLEYIQDPNSDQWTLMNQSTTIEAFSGFLDSVISTYKANALKGRE
AIEWVINNRLPLLPKIPECQKIVPAHPENDIDQFISHVETCWDDISRDVT
KAKDEFISRGAVIKENFTNLFFENIYVWGNQFS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005758mitochondrial intermembrane space
GO:0005739mitochondrion
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000103central nervous system
PLANA:0000208testis
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR037365Slowmo/Ups
IPR006797PRELI/MSF1_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006797PRELI/MSF1 domainPFAMPF04707PRELIcoord: 19..158
e-value: 1.9E-23
score: 83.0
IPR006797PRELI/MSF1 domainPROSITEPS50904PRELI_MSF1coord: 5..164
score: 19.106
IPR037365Slowmo/Ups familyPANTHERPTHR11158MSF1/PX19 RELATEDcoord: 6..158
NoneNo IPR availablePANTHERPTHR11158:SF17PROTEIN SLOWMOcoord: 6..158