Glyoxylate/hydroxypyruvate reductase B

Overview
NameGlyoxylate/hydroxypyruvate reductase B
Smed IDSMED30006344
Length (bp)1117
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Glyoxylate/hydroxypyruvate reductase B (SMED30006344) t-SNE clustered cells

Violin plots show distribution of expression levels for Glyoxylate/hydroxypyruvate reductase B (SMED30006344) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Glyoxylate/hydroxypyruvate reductase B (SMED30006344) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Glyoxylate/hydroxypyruvate reductase B (SMED30006344) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006344

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30006344SMESG000080490.1 SmedASXL_010322SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
cephalic gangliaSMED30006344SMESG000080490.1 dd_Smed_v4_41385_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30006344SMESG000080490.1 SMED_20236_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30006344SMESG000080490.1 SMED_20236_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Human
Match: GRHPR (glyoxylate and hydroxypyruvate reductase [Source:HGNC Symbol;Acc:HGNC:4570])

HSP 1 Score: 142.895 bits (359), Expect = 6.202e-39
Identity = 82/247 (33.20%), Postives = 136/247 (55.06%), Query Frame = 1 
Query:  274 NLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGM-KIIY---HQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIM 1002
            NL+V+  M+ G+D+L LD +  + +              +V    +  +D+T+E+ + L+L + RR  +AI+ + N            G  + +  +GIIGLG IGQ++A +    FG+ + +Y     R ++++     + +  E+    DF+V++C LT  T+ L N +  + MK +A  IN++RG +V  +DL  AL  G I+ AGLDV  PEPLP+ HPLL + N ++LPHIG+    TR+ M
Sbjct:   74 NLKVISTMSVGIDHLALDEIKKRGI--------------RVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLK-PFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTM 305
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Human
Match: GRHPR (glyoxylate and hydroxypyruvate reductase [Source:HGNC Symbol;Acc:HGNC:4570])

HSP 1 Score: 124.79 bits (312), Expect = 7.389e-32
Identity = 74/229 (32.31%), Postives = 124/229 (54.15%), Query Frame = 1 
Query:  274 NLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGM-KIIY---HQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNN 948
            NL+V+  M+ G+D+L LD +  + + V +                +  +D+T+E+ + L+L + RR  +AI+ + N            G  + +  +GIIGLG IGQ++A +    FG+ + +Y     R ++++     + +  E+    DF+V++C LT  T+ L N +  + MK +A  IN++RG +V  +DL  AL  G I+ AGLDV  PEPLP+ HPLL + N
Sbjct:   74 NLKVISTMSVGIDHLALDEIKKRGIRVGYT--------------PDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKP-FGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKN 287
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Human
Match: PHGDH (phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923])

HSP 1 Score: 103.99 bits (258), Expect = 5.203e-24
Identity = 78/254 (30.71%), Postives = 122/254 (48.03%), Query Frame = 1 
Query:  241 KTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQR--NKKSSCLFPYYE-NLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETR 993
            K   ++I     L+VV    +GVD +DL+    K ++V+    GN  S +++  C           GM++ L  AR+  +A  ++ +         +++G  +N K LGI+GLG IG+ +A +    FGMK I +    + + S  F   +  L E+ PL DF+ +  PL   T  L+N N     K    ++N  RG IV    L+ AL+ G  +GA LDV   EP P    L+   NV+  PH+G    E +
Sbjct:   58 KVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAEL-TC-----------GMIMCL--ARQIPQATASMKDGKWERK---KFMGTELNGKTLGILGLGRIGREVATRMQ-SFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVISCPHLGASTKEAQ 292
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Human
Match: PHGDH (phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923])

HSP 1 Score: 103.605 bits (257), Expect = 6.061e-24
Identity = 77/254 (30.31%), Postives = 121/254 (47.64%), Query Frame = 1 
Query:  241 KTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQR--NKKSSCLFPYYE-NLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETR 993
            K   ++I     L+VV    +GVD +DL+    K ++V+    GN  S +++              GM++ L  AR+  +A  ++ +         +++G  +N K LGI+GLG IG+ +A +    FGMK I +    + + S  F   +  L E+ PL DF+ +  PL   T  L+N N     K    ++N  RG IV    L+ AL+ G  +GA LDV   EP P    L+   NV+  PH+G    E +
Sbjct:   58 KVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELT------------CGMIMCL--ARQIPQATASMKDGKWERK---KFMGTELNGKTLGILGLGRIGREVATRMQ-SFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVISCPHLGASTKEAQ 292
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Human
Match: PHGDH (phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923])

HSP 1 Score: 103.99 bits (258), Expect = 9.022e-24
Identity = 78/254 (30.71%), Postives = 122/254 (48.03%), Query Frame = 1 
Query:  241 KTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQR--NKKSSCLFPYYE-NLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETR 993
            K   ++I     L+VV    +GVD +DL+    K ++V+    GN  S +++  C           GM++ L  AR+  +A  ++ +         +++G  +N K LGI+GLG IG+ +A +    FGMK I +    + + S  F   +  L E+ PL DF+ +  PL   T  L+N N     K    ++N  RG IV    L+ AL+ G  +GA LDV   EP P    L+   NV+  PH+G    E +
Sbjct:   58 KVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAEL-TC-----------GMIMCL--ARQIPQATASMKDGKWERK---KFMGTELNGKTLGILGLGRIGREVATRMQ-SFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVISCPHLGASTKEAQ 292
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Celegans
Match: C31C9.2 (pep chromosome:WBcel235:II:13636929:13638480:-1 gene:WBGene00007836.1 transcript:C31C9.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C31C9.2)

HSP 1 Score: 93.9745 bits (232), Expect = 1.960e-21
Identity = 81/302 (26.82%), Postives = 132/302 (43.71%), Query Frame = 1 
Query:  178 LELKLNNTLKDHVIGVLVFTGKTDFELIYDLPN-----------------------LRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKII-------YHQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETR 993
            +E +  + LK + I V V T +T  EL+  LP                        L++V    +GVD +D+    +  ++V+              N     S S +E+   LIL+ +R   +A  ++           +++G  V  + L ++GLG IG  +A +    FGMK+I         Q   K+  L     +L ++ P  D++ +  PL  QT++LIN   L   K    +INV RG IV   DLV++L  G   GA  DV + EP P+   L+    V+  PH+G   ++ +
Sbjct:   14 IEQECVDILKQNGIEVTVKTKQTKDELLVTLPQHDAVIVRSATKITAELLAASAGKLKLVGRAGTGVDNIDVPAASANKILVM--------------NTPQANSRSAAELTCTLILSLSRHVPQAAASMKAGKWARK---DFMGEEVYGRTLAVLGLGRIGSEVAVRLQ-AFGMKVIGFDPMVTKEQAEAKNIELL----SLEQIWPQADYITVHVPLIKQTENLINKETLAKCKKGVRIINVARGGIVNEVDLVESLNAGHAKGAAFDVFEQEP-PTFRELIDHPLVIATPHLGASTIDAQ 292
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Celegans
Match: ctbp-1 (C-terminal-binding protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20595])

HSP 1 Score: 75.0998 bits (183), Expect = 1.608e-14
Identity = 73/268 (27.24%), Postives = 125/268 (46.64%), Query Frame = 1 
Query:  202 LKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHN--PTIYYNSINE-YVGIN-VNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQ---RNKKSSCL-FPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDV-----VDPEPLPSAHPLLHMNNVMVLPH 966
            L + V  ++  + K + E +     L+VV  +  G+D +D+       + V     G++           + +DST    + LIL+  RRT    ++      TI  + + E  VG   V   VLGI+G G +G ++  +A   FG+ II++    R      L F     ++E +   D + + C L ++T+ +IN + L+  KS  Y++N +   ++  NDL  AL+ G + GA LDV      DP  L   +PL+   N++  PH
Sbjct:   97 LNEAVAALMYHSIKLEKEDLEKFKVLKVVFRIGYGIDNIDVKAATELGIAVCHAP-GDYVE---------DVADST----LSLILDLFRRTYWHAKSYSETRKTIGADQVRENAVGSKKVRGSVLGILGCGRVGTAVGLRAR-AFGLHIIFYDPFVREGHDKALGFERVYTMDEFMSRSDCISLHCNLGDETRGIINADSLRQCKSGVYIVNTSHAGLINENDLAAALKNGHVKGAALDVHDSVRFDPNCL---NPLVGCPNIINTPH 346
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Celegans
Match: ctbp-1 (C-terminal-binding protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20595])

HSP 1 Score: 74.7146 bits (182), Expect = 2.257e-14
Identity = 73/268 (27.24%), Postives = 125/268 (46.64%), Query Frame = 1 
Query:  202 LKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHN--PTIYYNSINE-YVGIN-VNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQ---RNKKSSCL-FPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDV-----VDPEPLPSAHPLLHMNNVMVLPH 966
            L + V  ++  + K + E +     L+VV  +  G+D +D+       + V     G++           + +DST    + LIL+  RRT    ++      TI  + + E  VG   V   VLGI+G G +G ++  +A   FG+ II++    R      L F     ++E +   D + + C L ++T+ +IN + L+  KS  Y++N +   ++  NDL  AL+ G + GA LDV      DP  L   +PL+   N++  PH
Sbjct:  218 LNEAVAALMYHSIKLEKEDLEKFKVLKVVFRIGYGIDNIDVKAATELGIAVCHAP-GDYVE---------DVADST----LSLILDLFRRTYWHAKSYSETRKTIGADQVRENAVGSKKVRGSVLGILGCGRVGTAVGLRAR-AFGLHIIFYDPFVREGHDKALGFERVYTMDEFMSRSDCISLHCNLGDETRGIINADSLRQCKSGVYIVNTSHAGLINENDLAAALKNGHVKGAALDVHDSVRFDPNCL---NPLVGCPNIINTPH 467
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Fly
Match: CG31673 (gene:FBgn0051673 transcript:FBtr0081422)

HSP 1 Score: 137.117 bits (344), Expect = 4.709e-37
Identity = 80/241 (33.20%), Postives = 123/241 (51.04%), Query Frame = 1 
Query:  274 NLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKS--SCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALET 990
             LR V  M+SG+D++D+     +      I  G+   +  VKN       + +++ + L++ + R        +         IN  +G  +   V+G  G G I Q++A +       KIIYH R +K         + +  ++L   DFLV++ PLTN+T+   N     LMK S+  +NV RG +V   DL DAL  G IS AGLDV  PEPLP+  PLL++ N ++LPH+GT  ++T
Sbjct:   74 QLRCVSTMSSGIDFVDIPEFQKRG-----IPLGHTPGV--VKN-------AVADLAIGLMIAAGRHFHAGRTEIERSQWKIEQINWMMGQEIRDSVIGFFGFGGISQAIAKRLQCWDVAKIIYHTRTRKENDGDFKAEHVSFEQLLQESDFLVVAAPLTNETREKFNGKAFNLMKRSSVFVNVARGGLVNQTDLHDALTNGTISAAGLDVTTPEPLPANSPLLNVPNCVILPHMGTQTMKT 300
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Fly
Match: CG31673 (gene:FBgn0051673 transcript:FBtr0339562)

HSP 1 Score: 132.494 bits (332), Expect = 1.985e-35
Identity = 80/241 (33.20%), Postives = 122/241 (50.62%), Query Frame = 1 
Query:  274 NLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKS--SCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALET 990
             LR V  M+SG+D++D+     +      I  G+   +  VKN       + +++ + L++ + R        +         IN  +G  +   V+G  G G I Q++A +       KIIYH R +K         + +  ++L   DFLV++ PLTN+T+   N     LMK S+  +NV RG +V   DL DAL  G IS AGLDV  PEPLP+  PLL++ N  +LPH+GT  ++T
Sbjct:   74 QLRCVSTMSSGIDFVDIPEFQKRG-----IPLGHTPGV--VKN-------AVADLAIGLMIAAGRHFHAGRTEIERSQWKIEQINWMMGQEIRDSVIGFFGFGGISQAIAKRLQCWDVAKIIYHTRTRKENDGDFKAEHVSFEQLLQESDFLVVAAPLTNETREKFNGKAFNLMKRSSVFVNVARGGLVNQTDLHDALTNGTISAAGLDVTTPEPLPANSPLLNVPN-FILPHMGTQTMKT 299
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Fly
Match: CG31674 (gene:FBgn0051674 transcript:FBtr0339563)

HSP 1 Score: 130.183 bits (326), Expect = 1.869e-34
Identity = 87/276 (31.52%), Postives = 142/276 (51.45%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSCLFPYYE----NLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN*YCSEPLIDIHY 1083
            P L+ V  M+SG++ +D+  L  +      I  G+  ++  V         + +++ + L++ +ARR  +  + + +     + +N  +G ++    +G  G G IGQ++A K  +GF +K ++Y  RN+ S  +   +     +   +L   DFL+I+ PLT +T  L N      MK +A L+NV RG IV  +DL +AL+   I  AGLDV+DPEPLPS   LL ++NV+V PH+G     TR    N   RN+   L       EP++   Y
Sbjct:   72 PQLKAVSTMSSGINNVDVPELKKRG-----IPLGSTPAMLTV---------AVADLTVGLLIAAARRFQEGRRKIDSDKWDKDHLNWMLGQDIRDSTVGFYGFGGIGQAVA-KRLMGFDIKRMLYTTRNRVSQDIEERFNAKKVDFETLLAESDFLIIASPLTKETLGLFNATVFNKMKETAVLVNVGRGKIVNQDDLYEALKSNRIFAAGLDVMDPEPLPSNDKLLTLDNVVVTPHVGYATRRTRVDAANLASRNVLKGL-----AGEPMLSPAY 327
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Fly
Match: CG31674 (gene:FBgn0051674 transcript:FBtr0081423)

HSP 1 Score: 130.183 bits (326), Expect = 1.869e-34
Identity = 87/276 (31.52%), Postives = 142/276 (51.45%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSCLFPYYE----NLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN*YCSEPLIDIHY 1083
            P L+ V  M+SG++ +D+  L  +      I  G+  ++  V         + +++ + L++ +ARR  +  + + +     + +N  +G ++    +G  G G IGQ++A K  +GF +K ++Y  RN+ S  +   +     +   +L   DFL+I+ PLT +T  L N      MK +A L+NV RG IV  +DL +AL+   I  AGLDV+DPEPLPS   LL ++NV+V PH+G     TR    N   RN+   L       EP++   Y
Sbjct:   72 PQLKAVSTMSSGINNVDVPELKKRG-----IPLGSTPAMLTV---------AVADLTVGLLIAAARRFQEGRRKIDSDKWDKDHLNWMLGQDIRDSTVGFYGFGGIGQAVA-KRLMGFDIKRMLYTTRNRVSQDIEERFNAKKVDFETLLAESDFLIIASPLTKETLGLFNATVFNKMKETAVLVNVGRGKIVNQDDLYEALKSNRIFAAGLDVMDPEPLPSNDKLLTLDNVVVTPHVGYATRRTRVDAANLASRNVLKGL-----AGEPMLSPAY 327
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Fly
Match: CG9331 (gene:FBgn0032889 transcript:FBtr0339560)

HSP 1 Score: 125.561 bits (314), Expect = 8.178e-33
Identity = 80/276 (28.99%), Postives = 139/276 (50.36%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGM-KIIYHQRNKKSSCLFPYYE----NLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN*YCSEPLIDIHY 1083
            P L+ +  M++G+DY+D+  +  +      I  G+  ++          + + +++ + L++ ++RR  +  + + N       +N  +G ++    +G  G G IGQ++A + S GF + K++Y  R +    +   +     + + +L   DF+VI+ PLT  T+ + N      MK +A L+N+ RG IV  +DL +AL+   I  AGLDV DPEPL     LL ++NV+VLPHIG+    TR  M      N+   L       EP++   Y
Sbjct:   71 PQLKSISTMSAGIDYVDVPEVKRRK-----IPLGHTPTV---------LNTAVADLAVGLLIAASRRFHEGRKTIDNDKWENYHLNWLLGQDIRDSTVGFYGFGGIGQAIAKRLS-GFDIDKVLYTTRRRVHKEIEEEFNAKKVDFDTLLAESDFVVIASPLTKDTQGVFNATAFNKMKQTAVLVNIARGKIVNQDDLYEALKANRIFSAGLDVTDPEPLSPKDKLLTLDNVVVLPHIGSATKRTRADMSTIAAHNVLRGL-----AGEPMLSPAY 326
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Zebrafish
Match: zgc:136493 (zgc:136493 [Source:ZFIN;Acc:ZDB-GENE-060512-216])

HSP 1 Score: 158.303 bits (399), Expect = 8.422e-45
Identity = 96/264 (36.36%), Postives = 146/264 (55.30%), Query Frame = 1 
Query:  247 DFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKK-----SSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRN 1023
            D +L+  LPNL+ V     GVD+LD+ ++ S  V              KV N  +   ++T++IGM L+L SAR+ ++  Q         +     +G +V+   LGIIG+G IG  +A +A  GF MKI+YH RN++      +    Y  ++ E+L   DF+++   L+ QT  LI+     +M+ ++  IN++RG +V  + LVDAL   +I  A LDV  PEPLP  HPLL   NV+V+PHIGT  LET  +M+ + + N
Sbjct:   81 DRDLLQSLPNLKAVINGGVGVDHLDIPLINSFGV--------------KVSNTPHVVDNATADIGMSLMLASARKIIEG-QHFSKFRESDDFPESTMGTDVSGATLGIIGMGRIGYKIAKRAQ-GFDMKILYHNRNRRPENEERAVGATYCASMTELLQRSDFVMVVVNLSPQTHKLISAKEFAMMRPNSTFINISRGLVVDQDALVDALLKKMIRAAALDVTYPEPLPRDHPLLSFPNVIVMPHIGTHTLETSQLMVERMVTN 328
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Zebrafish
Match: grhpra (glyoxylate reductase/hydroxypyruvate reductase a [Source:ZFIN;Acc:ZDB-GENE-040724-230])

HSP 1 Score: 139.813 bits (351), Expect = 5.555e-38
Identity = 87/260 (33.46%), Postives = 138/260 (53.08%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSCLFPYYENLN-EMLPL------VDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNL 1026
            PNL+V+  ++ G D+L +D +  + +              +V    +  +D+T+E+ + L+L +ARR  + ++ + N            G  ++   +G+IGLG IG ++A +    FG+K ++Y  R  K     P  E ++ E +PL       DF+V+SC LT  T+ L +      MK ++  IN +RG++V   DL +AL  G I+ AGLDV  PEPLP+ HPLL + N +VLPHIG+    TR +M   T  NL
Sbjct:   73 PNLKVISTLSVGFDHLAIDEIKKRGI--------------RVGYTPDVLTDATAELTVALLLATARRLPEGVEEVKNGGWSTWKPLWLCGYGLSGSTVGVIGLGRIGLAIARRLKP-FGVKKLLYTGRKPK-----PEAEEVDGEYVPLDTLVRESDFVVVSCSLTPDTQGLCDKTFFGKMKKTSVFINSSRGAVVNQEDLFEALSSGQIAAAGLDVTSPEPLPTNHPLLTLKNCVVLPHIGSATYSTRGVMSELTANNL 312
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Zebrafish
Match: grhprb (glyoxylate reductase/hydroxypyruvate reductase b [Source:ZFIN;Acc:ZDB-GENE-040426-1847])

HSP 1 Score: 136.732 bits (343), Expect = 1.463e-36
Identity = 93/280 (33.21%), Postives = 144/280 (51.43%), Query Frame = 1 
Query:  220 GVL-VFTGKTDFELIYDL--PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIY---HQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            G+L V T K D +L+ D+  PNL+V+  M+ G D+L L+ L    ++   I    F    +V       +D+ +E+ + L+L ++RR ++A                  G  +    +GI+GLG IG ++A +       K IY     R + ++ +   Y +L+E+    DFL I C LT +T  + N N    MK +A  IN +RG +V   DL +AL  G+I+GAGLDV  PEPLP+ HPL  + N ++LPHI + +  TR+ M      NL   L+
Sbjct:   77 GILCVLTEKIDAQLL-DVAGPNLKVLSTMSVGYDHLSLEELKKSLLIWACI----FCRGIRVGYTPEVLTDAVAELTVALLLATSRRLIEATHEAKTGGWGTWRTMWLCGHELANSTVGILGLGRIGVAIAERLKPFKVKKFIYTDVEPRTELANMINAEYVSLDELAKQSDFLAICCALTPETHGICNWNLFSKMKKNAIFINTSRGGVVNQEDLYEALSTGLIAGAGLDVTTPEPLPTHHPLYTLKNCVILPHIASASYTTRNAMSALAANNLLAGLR 351
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Zebrafish
Match: grhprb (glyoxylate reductase/hydroxypyruvate reductase b [Source:ZFIN;Acc:ZDB-GENE-040426-1847])

HSP 1 Score: 136.732 bits (343), Expect = 1.463e-36
Identity = 93/280 (33.21%), Postives = 144/280 (51.43%), Query Frame = 1 
Query:  220 GVL-VFTGKTDFELIYDL--PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIY---HQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            G+L V T K D +L+ D+  PNL+V+  M+ G D+L L+ L    ++   I    F    +V       +D+ +E+ + L+L ++RR ++A                  G  +    +GI+GLG IG ++A +       K IY     R + ++ +   Y +L+E+    DFL I C LT +T  + N N    MK +A  IN +RG +V   DL +AL  G+I+GAGLDV  PEPLP+ HPL  + N ++LPHI + +  TR+ M      NL   L+
Sbjct:   77 GILCVLTEKIDAQLL-DVAGPNLKVLSTMSVGYDHLSLEELKKSLLIWACI----FCRGIRVGYTPEVLTDAVAELTVALLLATSRRLIEATHEAKTGGWGTWRTMWLCGHELANSTVGILGLGRIGVAIAERLKPFKVKKFIYTDVEPRTELANMINAEYVSLDELAKQSDFLAICCALTPETHGICNWNLFSKMKKNAIFINTSRGGVVNQEDLYEALSTGLIAGAGLDVTTPEPLPTHHPLYTLKNCVILPHIASASYTTRNAMSALAANNLLAGLR 351
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Zebrafish
Match: grhprb (glyoxylate reductase/hydroxypyruvate reductase b [Source:ZFIN;Acc:ZDB-GENE-040426-1847])

HSP 1 Score: 135.961 bits (341), Expect = 3.099e-36
Identity = 88/267 (32.96%), Postives = 138/267 (51.69%), Query Frame = 1 
Query:  220 GVL-VFTGKTDFELIYDL--PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIY---HQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIM 1002
            G+L V T K D +L+ D+  PNL+V+  M+ G D+L L+ L  + + V +                   +D+ +E+ + L+L ++RR ++A                  G  +    +GI+GLG IG ++A +       K IY     R + ++ +   Y +L+E+    DFL I C LT +T  + N N    MK +A  IN +RG +V   DL +AL  G+I+GAGLDV  PEPLP+ HPL  + N ++LPHI + +  TR+ M
Sbjct:   77 GILCVLTEKIDAQLL-DVAGPNLKVLSTMSVGYDHLSLEELKKRGIRVGYT--------------PEVLTDAVAELTVALLLATSRRLIEATHEAKTGGWGTWRTMWLCGHELANSTVGILGLGRIGVAIAERLKPFKVKKFIYTDVEPRTELANMINAEYVSLDELAKQSDFLAICCALTPETHGICNWNLFSKMKKNAIFINTSRGGVVNQEDLYEALSTGLIAGAGLDVTTPEPLPTHHPLYTLKNCVILPHIASASYTTRNAM 328
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Xenopus
Match: psmd3 (proteasome 26S subunit, non-ATPase 3 [Source:Xenbase;Acc:XB-GENE-958537])

HSP 1 Score: 164.081 bits (414), Expect = 7.747e-47
Identity = 99/268 (36.94%), Postives = 151/268 (56.34%), Query Frame = 1 
Query:  253 ELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKS-----SCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            EL+  LPNL+VV     GVD++DL ++ S  +              KV N     +D+T+++GM L+L SAR  ++  + L +P      +N +VG ++ +  LGIIG+G IG ++A +A   F M+I+YH R ++           Y  ++ ++L   DF++I   L+ +T  LI    L+LMK +A LIN++RG +V  + LV+AL  G I  A LDV  PEPLP  HPLL M NV++ PHIGT + +TR  +  K   N  D ++
Sbjct:   82 ELLESLPNLKVVGSSGVGVDHMDLKLIASYGI--------------KVTNTPRVGNDATADLGMALMLASARNIVEVNRILCSPETKEFDVN-WVGDDITEATLGIIGMGNIGYNIALRAK-AFRMRILYHNRKRRDVKEEMEVGAVYCSSIADLLQQSDFVMIVVELSPETYKLIGKRELQLMKPTATLINISRGKVVDQDALVEALENGTIKAAALDVTYPEPLPRKHPLLTMKNVILTPHIGTASDKTRRKVAEKFAANAADIIK 333
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Xenopus
Match: psmd3 (proteasome 26S subunit, non-ATPase 3 [Source:Xenbase;Acc:XB-GENE-958537])

HSP 1 Score: 164.081 bits (414), Expect = 1.634e-46
Identity = 99/265 (37.36%), Postives = 149/265 (56.23%), Query Frame = 1 
Query:  253 ELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKS-----SCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKD 1032
            EL+  LPNL+VV     GVD++DL ++ S  +              KV N     +D+T+++GM L+L SAR  ++  + L +P      +N +VG ++ +  LGIIG+G IG ++A +A   F M+I+YH R ++           Y  ++ ++L   DF++I   L+ +T  LI    L+LMK +A LIN++RG +V  + LV+AL  G I  A LDV  PEPLP  HPLL M NV++ PHIGT + +TR  +  K   N  D
Sbjct:  119 ELLESLPNLKVVGSSGVGVDHMDLKLIASYGI--------------KVTNTPRVGNDATADLGMALMLASARNIVEVNRILCSPETKEFDVN-WVGDDITEATLGIIGMGNIGYNIALRAK-AFRMRILYHNRKRRDVKEEMEVGAVYCSSIADLLQQSDFVMIVVELSPETYKLIGKRELQLMKPTATLINISRGKVVDQDALVEALENGTIKAAALDVTYPEPLPRKHPLLTMKNVILTPHIGTASDKTRRKVAEKFAANAAD 367
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Xenopus
Match: grhpr.2 (glyoxylate reductase/hydroxypyruvate reductase, gene 2 [Source:NCBI gene;Acc:493279])

HSP 1 Score: 143.28 bits (360), Expect = 2.527e-39
Identity = 83/248 (33.47%), Postives = 134/248 (54.03%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSC---LFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIM 1002
            P+L+V+  ++ G D+L LD +  + + V +                +  +D+T+E+ + L+L + RR  +AIQ + N      +     G  ++   +G+IGLG IG ++A +    FG+K  +Y  R  K  C   L   + +  ++    DF+++SC LT +T    N +  K MK ++  IN +RGS+V   DL +AL  G I+ AGLDV  PEPLP+ HPLL + N ++LPHIG+    TR+ M
Sbjct:   51 PSLKVISTLSVGFDHLALDEIKKRGIRVGYT--------------PDVLTDATAELTVALLLTTCRRLPEAIQEVKNGGWKTWAPMWMCGYGLSNSTVGVIGLGRIGLAIARRLK-PFGVKKFLYTGRQPKPECDEELNAEFVSCEKLAEESDFVIVSCSLTPKTVGFCNKDFFKKMKKTSIFINTSRGSVVNQEDLYEALASGQIAAAGLDVTTPEPLPTDHPLLSLKNCVILPHIGSATYATRNAM 283
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Xenopus
Match: grhpr.2 (glyoxylate reductase/hydroxypyruvate reductase, gene 2 [Source:NCBI gene;Acc:493279])

HSP 1 Score: 143.28 bits (360), Expect = 2.926e-39
Identity = 83/248 (33.47%), Postives = 134/248 (54.03%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSC---LFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIM 1002
            P+L+V+  ++ G D+L LD +  + +              +V    +  +D+T+E+ + L+L + RR  +AIQ + N      +     G  ++   +G+IGLG IG ++A +    FG+K  +Y  R  K  C   L   + +  ++    DF+++SC LT +T    N +  K MK ++  IN +RGS+V   DL +AL  G I+ AGLDV  PEPLP+ HPLL + N ++LPHIG+    TR+ M
Sbjct:   55 PSLKVISTLSVGFDHLALDEIKKRGI--------------RVGYTPDVLTDATAELTVALLLTTCRRLPEAIQEVKNGGWKTWAPMWMCGYGLSNSTVGVIGLGRIGLAIARRLK-PFGVKKFLYTGRQPKPECDEELNAEFVSCEKLAEESDFVIVSCSLTPKTVGFCNKDFFKKMKKTSIFINTSRGSVVNQEDLYEALASGQIAAAGLDVTTPEPLPTDHPLLSLKNCVILPHIGSATYATRNAM 287
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Xenopus
Match: grhpr.2 (glyoxylate reductase/hydroxypyruvate reductase, gene 2 [Source:NCBI gene;Acc:493279])

HSP 1 Score: 142.895 bits (359), Expect = 4.359e-39
Identity = 83/248 (33.47%), Postives = 134/248 (54.03%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSC---LFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIM 1002
            P+L+V+  ++ G D+L LD +  + +              +V    +  +D+T+E+ + L+L + RR  +AIQ + N      +     G  ++   +G+IGLG IG ++A +    FG+K  +Y  R  K  C   L   + +  ++    DF+++SC LT +T    N +  K MK ++  IN +RGS+V   DL +AL  G I+ AGLDV  PEPLP+ HPLL + N ++LPHIG+    TR+ M
Sbjct:   60 PSLKVISTLSVGFDHLALDEIKKRGI--------------RVGYTPDVLTDATAELTVALLLTTCRRLPEAIQEVKNGGWKTWAPMWMCGYGLSNSTVGVIGLGRIGLAIARRLK-PFGVKKFLYTGRQPKPECDEELNAEFVSCEKLAEESDFVIVSCSLTPKTVGFCNKDFFKKMKKTSIFINTSRGSVVNQEDLYEALASGQIAAAGLDVTTPEPLPTDHPLLSLKNCVILPHIGSATYATRNAM 292
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Mouse
Match: Grhpr (glyoxylate reductase/hydroxypyruvate reductase [Source:MGI Symbol;Acc:MGI:1923488])

HSP 1 Score: 142.895 bits (359), Expect = 3.917e-39
Identity = 94/295 (31.86%), Postives = 153/295 (51.86%), Query Frame = 1 
Query:  154 ESYNFINPLELKLNNTLKDHVIGV----LVFTGKTDFELIYDL-PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGM-KIIYHQRNKKSSCLFPYYENLNEMLPLV------DFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIM 1002
            E +N  +P+  K    L+  V+G        + + D +L+     NLRV+  ++ GVD+L LD +  + +              +V       +D+T+E+ + L+L + RR  +AI+ + N      S     G  +++  +GI+GLG IGQ++A +    FG+ + +Y  R  +        E   E +P+       DF+V+SC LT  T  L + +  + MK++A  IN++RG +V   DL  AL  G I+ AGLDV  PEPLP +HPLL + N ++LPHIG+   +TR+ M
Sbjct:   32 EQWNSDDPIPRK---DLEQGVVGAHGLLCRLSDRVDKKLLDAAGANLRVISTLSVGVDHLALDEIKKRGI--------------RVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIARRLK-PFGVQRFLYTGRQPRPQ---EAAEFQAEFVPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEPLPPSHPLLTLKNCVILPHIGSATYKTRNTM 305
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Mouse
Match: Grhpr (glyoxylate reductase/hydroxypyruvate reductase [Source:MGI Symbol;Acc:MGI:1923488])

HSP 1 Score: 108.612 bits (270), Expect = 2.626e-27
Identity = 70/220 (31.82%), Postives = 113/220 (51.36%), Query Frame = 1 
Query:  274 NLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGM-KIIYHQRNKKSSCLFPYYENLNEMLPLV------DFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEP 912
            NLRV+  ++ GVD+L LD +  + +              +V       +D+T+E+ + L+L + RR  +AI+ + N      S     G  +++  +GI+GLG IGQ++A +    FG+ + +Y  R  +        E   E +P+       DF+V+SC LT  T  L + +  + MK++A  IN++RG +V   DL  AL  G I+ AGLDV  PEP
Sbjct:   21 NLRVISTLSVGVDHLALDEIKKRGI--------------RVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIARRLKP-FGVQRFLYTGRQPRPQ---EAAEFQAEFVPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEP 222
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Mouse
Match: Phgdh (3-phosphoglycerate dehydrogenase [Source:MGI Symbol;Acc:MGI:1355330])

HSP 1 Score: 99.7525 bits (247), Expect = 1.838e-22
Identity = 75/254 (29.53%), Postives = 122/254 (48.03%), Query Frame = 1 
Query:  241 KTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQR--NKKSSCLFPYYE-NLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETR 993
            K   ++I     L+VV    +GVD +DL+    K ++V+    GN  S +++  C           GM++ L  AR+  +A  ++ +         +++G  +N K LGI+GLG IG+ +A +    FGMK + +    + + +  F   +  L E+ PL DF+ +  PL   T  L+N +     K    ++N  RG IV    L+ AL+ G  +GA LDV   EP P    L+   NV+  PH+G    E +
Sbjct:   58 KVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAEL-TC-----------GMIMCL--ARQIPQATASMKDGKWDRK---KFMGTELNGKTLGILGLGRIGREVATRMQ-SFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVISCPHLGASTKEAQ 292
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Mouse
Match: Ctbp1 (C-terminal binding protein 1 [Source:MGI Symbol;Acc:MGI:1201685])

HSP 1 Score: 90.8929 bits (224), Expect = 6.277e-20
Identity = 73/263 (27.76%), Postives = 117/263 (44.49%), Query Frame = 1 
Query:  277 LRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYN--SINEYV--GINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQ----RNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLP-SAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSL 1038
            LR++  + SG D +D+       + V  +   +            E +DST    +  ILN  RRT    QAL   T   +   I E       +  + LGIIGLG +GQ++A +A   FG  ++++        + +        L ++L   D + + C L     HLIN   +K M+  A+L+N  RG +V    L  AL+ G I GA LDV + EP   S  PL    N++  PH   ++ +    M  +  R ++ ++
Sbjct:   18 LRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASV----------EETADST----LCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAK-AFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAI 265
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Mouse
Match: Ctbp1 (C-terminal binding protein 1 [Source:MGI Symbol;Acc:MGI:1201685])

HSP 1 Score: 90.5077 bits (223), Expect = 1.511e-19
Identity = 73/263 (27.76%), Postives = 117/263 (44.49%), Query Frame = 1 
Query:  277 LRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYN--SINEYV--GINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQ----RNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLP-SAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSL 1038
            LR++  + SG D +D+       + V  +   +            E +DST    +  ILN  RRT    QAL   T   +   I E       +  + LGIIGLG +GQ++A +A   FG  ++++        + +        L ++L   D + + C L     HLIN   +K M+  A+L+N  RG +V    L  AL+ G I GA LDV + EP   S  PL    N++  PH   ++ +    M  +  R ++ ++
Sbjct:   81 LRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASV----------EETADST----LCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAK-AFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAI 328
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. UniProt/SwissProt
Match: sp|B2VCD1|GHRB_ERWT9 (Glyoxylate/hydroxypyruvate reductase B OS=Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99) OX=465817 GN=ghrB PE=3 SV=1)

HSP 1 Score: 170.244 bits (430), Expect = 9.347e-49
Identity = 99/272 (36.40%), Postives = 148/272 (54.41%), Query Frame = 1 
Query:  220 GVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPY---YENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNL 1026
            G+L   GK D E +   P LRV   ++ G D  D+  L  + V+++              +     +++ ++  M L+L+SARR ++  + + +     +  +++ GI+V+ K LGI+G+G IG +LA +A LGFGM I+Y+ R         +   Y +L+ +L   DFL IS PLT QT HLI   +L  MK SA LIN  RG +V    L+ AL+ G +  AGLDV + EPLP +  LL + NV+ LPHIG+   ETR  M    + NL
Sbjct:   48 GILGSGGKVDAEFLRQAPKLRVASSISVGYDNFDVAALNDRGVLLM--------------HTPTVLTETVADTMMALVLSSARRVVEMAERVKSGEWRGSISSDWFGIDVHHKKLGILGMGRIGLALAQRAHLGFGMPILYNARKHHDEAEQRFDAEYCDLDTLLAESDFLCISLPLTEQTHHLIGREQLAKMKRSAILINAGRGPVVDEQALIAALKDGTLHAAGLDVFEQEPLPVSSELLALRNVVALPHIGSATHETRYGMAKDAVDNL 305
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. UniProt/SwissProt
Match: sp|Q8FCF1|GHRB_ECOL6 (Glyoxylate/hydroxypyruvate reductase B OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=ghrB PE=3 SV=2)

HSP 1 Score: 160.999 bits (406), Expect = 3.866e-45
Identity = 102/325 (31.38%), Postives = 171/325 (52.62%), Query Frame = 1 
Query:   82 LQPTILLIGF--DSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQR--NKKSSCLF-PYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            ++P+++L     D LL    ++  + +  N ++P  ++ N  +     G+L      D  L+  +P LR    ++ G D  D+D L ++ ++++              +     +++ ++  M L+L++ARR ++  + +       +   ++ G +V+ K LGI+G+G IG +LA +A  GF M I+Y+ R  +K++   F   Y NL+ +L   DF+ +  PLT++T HL    +   MKSSA  IN  RG +V  N L+ AL+ G I  AGLDV + EPL    PLL M NV+ +PHIG+   ETR  M    + NL D+LQ
Sbjct:    1 MKPSVILYKALPDDLLQRLQEHFTVHQVAN-LSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLM--------------HTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCNLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQ 310
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. UniProt/SwissProt
Match: sp|A4W577|GHRB_ENT38 (Glyoxylate/hydroxypyruvate reductase B OS=Enterobacter sp. (strain 638) OX=399742 GN=ghrB PE=3 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 7.514e-45
Identity = 101/330 (30.61%), Postives = 170/330 (51.52%), Query Frame = 1 
Query:   82 LQPTILLIGFDSLLSESSKNRVLEESYNF-----INPLELKLNNTLKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPY---YENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN 1047
            ++P+++L  + +L  +  K   LEE +       +NP  +  +        G+L  + K D  L+  +P LR    ++ G D  D+D L ++ ++++   +                +++ ++  M L+L++ARR ++  + +       +   ++ G++V+ K LGI+G+G IG +LA +A  GF M I+Y+ R   S     +   Y  L  +L   D++ +  PLT++T HLI     + MK SA  IN  RG +V    L++AL+ G I  AGLDV + EPLP   PLL M+NV+ LPHIG+   ETR  M    + NL ++L  N
Sbjct:    1 MKPSVIL--YKTLPDDLQKR--LEEHFTVTQMKNLNPETVAEHADAFASAAGLLGSSEKVDTALLEKMPKLRATSTISVGYDNFDVDALNTRKILLMHTPYA--------------LTETVADTLMALVLSTARRVVEVAERVKAGEWTKSIGPDWFGVDVHGKTLGIVGMGRIGLALAQRAHFGFNMPILYNARRHHSEAEERFEARYCELETLLQEADYVCLILPLTDETHHLIGKAEFEKMKKSAIFINAGRGPVVDEKALIEALQKGEIHAAGLDVFEQEPLPVDSPLLTMSNVVSLPHIGSATHETRYNMAATAVDNLINALNGN 312
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. UniProt/SwissProt
Match: sp|B1IZP1|GHRB_ECOLC (Glyoxylate/hydroxypyruvate reductase B OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) OX=481805 GN=ghrB PE=3 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 8.090e-45
Identity = 101/325 (31.08%), Postives = 171/325 (52.62%), Query Frame = 1 
Query:   82 LQPTILLIGF--DSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQR--NKKSSCLF-PYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            ++P+++L     D LL    ++  + +  N ++P  ++ N  +     G+L      D  L+  +P LR    ++ G D  D+D L ++ ++++              +     +++ ++  M L+L++ARR ++  + +       +   ++ G +V+ K LGI+G+G IG +LA +A  GF M I+Y+ R  +K++   F   Y +L+ +L   DF+ +  PLT++T HL    +   MKSSA  IN  RG +V  N L+ AL+ G I  AGLDV + EPL    PLL M NV+ +PHIG+   ETR  M    + NL D+LQ
Sbjct:    1 MKPSVILYKALPDDLLQRLQEHFTVHQVAN-LSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLM--------------HTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATYETRYGMAACAVDNLIDALQ 310
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. UniProt/SwissProt
Match: sp|B1LJB3|GHRB_ECOSM (Glyoxylate/hydroxypyruvate reductase B OS=Escherichia coli (strain SMS-3-5 / SECEC) OX=439855 GN=ghrB PE=3 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 9.781e-45
Identity = 101/325 (31.08%), Postives = 171/325 (52.62%), Query Frame = 1 
Query:   82 LQPTILLIGF--DSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQR--NKKSSCLF-PYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            ++P+++L     D LL    ++  + +  N ++P  ++ N  +     G+L      D  L+  +P LR    ++ G D  D+D L ++ ++++              +     +++ ++  M L+L++ARR ++  + +       +   ++ G +V+ K LGI+G+G IG +LA +A  GF M I+Y+ R  +K++   F   Y +L+ +L   DF+ +  PLT++T HL    +   MKSSA  IN  RG +V  N L+ AL+ G I  AGLDV + EPL    PLL M NV+ +PHIG+   ETR  M    + NL D+LQ
Sbjct:    1 MKPSVILYKALPDDLLQRLQEHFTVHQVAN-LSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLM--------------HTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAQFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQ 310
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. TrEMBL
Match: G3VP78 (Uncharacterized protein OS=Sarcophilus harrisii OX=9305 GN=LOC100934948 PE=3 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 1.402e-54
Identity = 113/305 (37.05%), Postives = 177/305 (58.03%), Query Frame = 1 
Query:  148 LEESYNFINPLELKLNNT-LKDHVIGVLVFTGKT--DFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKK-----SSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSL 1038
            L++ +N +   E   N T     +  + ++ GK   D EL+  LP L+++    +G+D+LDL+++ S         FG      K+ N  +  ++ST+++GM L+L +ARR L+ I+   +P   Y S+N ++G +V    LGIIG+G IG  +A +A   F MKI+YH RN++      +    Y E L+E+L   DF+++   LT QT  LI    L LMK +A LIN+ RG +V  + LV+AL+ GII  AGLDV  PEPLP +HPLL + NV++ PHIG+   ++R +M+   + +L  +L
Sbjct:   28 LKKQFNLVTMQEFLENKTHFSQKIQAIYIWGGKPVIDKELLTSLPTLKIIVNSGAGLDHLDLNLIAS---------FG-----VKLANTPHAVTNSTADMGMALLLATARRILEGIEVATSPDTKYFSLN-WMGQDVTGSTLGIIGMGNIGYKVAQRAK-AFEMKILYHNRNRRKVEEEQAVGAHYCEKLDELLQQSDFVMLVLSLTPQTHKLIGKRELGLMKPTAILINIGRGQLVDQDALVEALQTGIIKAAGLDVTYPEPLPRSHPLLKLKNVILTPHIGSATHQSRRLMMENMVESLLAAL 316
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. TrEMBL
Match: A0A0L8HYA2 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22002506mg PE=3 SV=1)

HSP 1 Score: 188.348 bits (477), Expect = 6.348e-53
Identity = 125/350 (35.71%), Postives = 193/350 (55.14%), Query Frame = 1 
Query:   67 SMSNYLQPTILL-------IGFDSLLSESSKNRVLEE-SYNFINPLELKLNNTLKDHVIGVLVFTGKTDF--ELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQ-ALHN--PTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSS-----CLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN*YCSE 1062
            +M+  ++P++L+           S L+E+  +R+      NF++  +++ N  +K  ++G++     ++    LI  LPNLRV+     GVD+LDL     K +              +V N     SDST+E+ + LIL   R+ ++ ++ ++ N  P  +  S+   +G NV KK LGI+G+G IG  +A +A+  FGMKI+YH R ++S+         +Y  L +MLP  D LVI+CP T QT +LI+    +LMK ++ L+N+ RG IV T+ LV AL+   I  A LDV DPEPLP  HPLL M NV++  H GT+  ETR  M++  + NLK  L+     SE
Sbjct:    6 NMAMQIKPSVLICLRTVNNTKLRSNLTETCLSRLRNHFQVNFLD--DIQQNPNIKKDIVGIVTPGPDSNVINRLITTLPNLRVISNHGMGVDHLDLKWAKEKGL--------------RVGNTRYVVSDSTAELAITLILVVTRKIVQGVRMSMENEHPNFFCPSL---LGTNVAKKNLGIVGMGDIGLKIALRAT-AFGMKILYHNRTQRSNEDEDRVKATFYPRLQDMLPEADVLVIACPCTEQTINLISTEEFRLMKKTSLLVNIARGKIVNTDALVKALQSNEIQSAALDVTDPEPLPRGHPLLSMPNVVITTHCGTYTYETRLEMIDLVIENLKCGLEGKVMPSE 335
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. TrEMBL
Match: A0A4X2M045 (Uncharacterized protein OS=Vombatus ursinus OX=29139 GN=LOC114036049 PE=3 SV=1)

HSP 1 Score: 187.578 bits (475), Expect = 8.184e-53
Identity = 111/305 (36.39%), Postives = 173/305 (56.72%), Query Frame = 1 
Query:  148 LEESYNFINPLELKLNNT-LKDHVIGVLVFTGKT--DFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKK-----SSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSL 1038
            L++ +N I   E   N       +  + ++ GK   D EL+  LP L+++    +G+D+LDL+++ S         FG      K+ N S   ++ST+++GM L+L SARR L+  +   +P   + ++N ++G  V    LGIIG+G IG  +A +A   F MKI+YH RN++      +    Y   L+E+L   DF+++   LT QT   I    L LMK +A LIN+ RG +V  + LV+AL+ GII  AGLDV DPEPLP +HPLL + NV++ PHIG+   ++R +M+   + +L  +L
Sbjct:   28 LKKHFNLITMREFLENKIHFSQKIQAIYIWGGKPHIDQELLQSLPTLKIIVSPGAGLDHLDLNLIAS---------FG-----VKLANTSRAVTNSTADLGMALLLASARRILEGNEIATSPDTKHFNVN-WMGQEVTGSTLGIIGMGRIGYKIAQRAK-AFEMKILYHNRNRRKVEEEQAVGAHYCAKLDELLQQSDFVMLVVSLTPQTHKFIGKRELGLMKPTASLINIGRGQLVDQDALVEALQTGIIKAAGLDVTDPEPLPRSHPLLKLKNVILTPHIGSATHQSRHLMMENMVESLLAAL 316
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. TrEMBL
Match: F7DDZ3 (Uncharacterized protein OS=Monodelphis domestica OX=13616 GN=LOC100023635 PE=3 SV=2)

HSP 1 Score: 187.578 bits (475), Expect = 9.817e-53
Identity = 119/332 (35.84%), Postives = 183/332 (55.12%), Query Frame = 1 
Query:   70 MSNYLQPTILLIGFDSLLSESSKN-RVLEESYNFINPLEL---KLNNTLKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKK-----SSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSL 1038
            M + + P +L+  F  L   ++ + + L++ +N I   E    K+N + K   I +       D EL+  LP L+++    +G+D+LDL+++ S         FG      K+ N     S+ST++ GM L+L SARR L+  +   +P   Y SIN + G  V    LGIIG+G+IG  +A +A   F MKI+YH RN++      +    Y   L+E+L L DF+++   LT  T  +I    L LMKS+A LIN+ RG +V  + LV+AL+ GII  A LDV  PEPLP +HPLL + NV++ PHIG+   ++R  M+   + +L  +L
Sbjct:    3 MQDQVLPCVLISNFGKLYGVNTDHVKDLKKHFNLITMQEFLQDKMNLSQKIQAIYLWGAEPHIDRELLASLPALKIIASSGTGLDHLDLNLIAS---------FG-----VKLANTPQAVSNSTADFGMALLLASARRILEGNEIALSPDTKYFSIN-WTGQEVTGCTLGIIGMGSIGYKVAQRAK-AFDMKILYHNRNRRKVEEEQAVGAHYCAKLDELLQLSDFVMLVLRLTPDTHKMIGKRELGLMKSTAILINIGRGQLVDQDALVEALQTGIIKAAALDVTYPEPLPRSHPLLKLKNVILTPHIGSATFQSRRAMMEDMVESLLAAL 318
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. TrEMBL
Match: A0A093I942 (Uncharacterized protein (Fragment) OS=Struthio camelus australis OX=441894 GN=N308_02902 PE=3 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 2.347e-52
Identity = 107/271 (39.48%), Postives = 163/271 (60.15%), Query Frame = 1 
Query:  247 DFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNP-TIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKK-----SSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            D EL+  LP L+VV     G+D+LDL++L S         FG      KV N     S  T+++GM L+L SARR ++  Q   +P T Y+ +  +++G+ V+   LGIIG+G IG  +A +A   F MKI+YH RN++     S+    Y + ++++L   DF++++  LT QT+ LI    L+LMK +A LIN++RG +V  + LV+AL+  +I  A LDV  PEPLP  HPLL M NV+V PHIG+   ETR +M+   + +++ +L+
Sbjct:    9 DKELLQSLPMLKVVASSGVGIDHLDLNLLSS---------FG-----VKVSNTPFVVSTDTADLGMALMLASARRLVEGYQMAVSPDTEYFPA--DWLGVEVSGTTLGIIGMGTIGYKVAQRAK-AFDMKILYHNRNQRNKEEESAVGAIYCKKIDDLLQQSDFVILAVVLTPQTRKLIGKRELELMKPTATLINISRGLVVDQDALVEALQNKVIKAAALDVTYPEPLPRDHPLLKMKNVVVTPHIGSATKETRRLMMENMIESMQAALR 262
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Cavefish
Match: zgc:136493 (probable 2-ketogluconate reductase [Source:NCBI gene;Acc:103030986])

HSP 1 Score: 167.162 bits (422), Expect = 4.312e-48
Identity = 109/282 (38.65%), Postives = 159/282 (56.38%), Query Frame = 1 
Query:  208 DHVIGVLVFTG--KTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSIN---EYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFP-----YYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRN 1023
            D +  V V+ G  K D  L+  LP L+ V     GVD+LD+ ++             N F + KV N  +   ++T++IGM L+L SAR+ ++A     N + +Y S +     +G +V+   LGIIG+G IG  +A +A  GF MKI+YH R+++           Y E + E+L   DF+++   L+ QT  LI    L +MKSS+ LIN++RG +V  + LVDAL+  +I  A LDV  PEPLP  HPLL   NV+VLPHIGT  +ET  IM+ + + N
Sbjct:   78 DKIQAVFVWGGALKVDRGLLQSLPKLKAVVNGGVGVDHLDISLI-------------NSFGV-KVSNTPHVVDNATADIGMGLMLASARKIIQA----DNFSRHYESADMPESSMGNDVSGATLGIIGMGRIGYKVARRA-YGFDMKILYHNRSRRKEEEERAVGAVYCEKMEELLQKSDFVMVVVNLSPQTHKLIGAKELAMMKSSSTLINISRGLVVDQDALVDALQRKVIKAAALDVTYPEPLPRGHPLLSFPNVIVLPHIGTHTVETSQIMVERMVTN 340
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Cavefish
Match: grhpra (glyoxylate and hydroxypyruvate reductase [Source:NCBI gene;Acc:103046658])

HSP 1 Score: 149.443 bits (376), Expect = 1.243e-41
Identity = 92/267 (34.46%), Postives = 142/267 (53.18%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSC--LFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN*YCSE 1062
            PNL+V+  ++ G D+L +D +  + +              +V    +  +D+T+E+ + L+L +ARR  + IQ + +            G  ++   +G+IGLG IG ++A +  + FG+K ++Y  R  K     +   Y  L+ +L   DF+V+SC LT  T+ L N      MK +A  IN +RG++V   DL +AL  G I+ AGLDV  PEPLP+ HPLL +NN +VLPHIG+    TR IM   +  NL   L  +   SE
Sbjct:   73 PNLKVISTLSVGFDHLAIDEVKKRGI--------------RVGYTPDVLTDATAELTVALLLATARRLPEGIQEVKSGGWSTWKPLWLCGYGLSGSTVGVIGLGRIGLAIARRL-MPFGVKRLLYSGRQPKPQAQEVDGEYVPLDTLLSESDFVVVSCALTPDTQGLCNKAFFSKMKKTAVFINTSRGAVVNQEDLFEALSTGQIAAAGLDVTTPEPLPTDHPLLTLNNCVVLPHIGSATYSTRGIMAQLSANNLLAGLSGDAMASE 324
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Cavefish
Match: grhprb (glyoxylate reductase/hydroxypyruvate reductase b [Source:ZFIN;Acc:ZDB-GENE-040426-1847])

HSP 1 Score: 131.339 bits (329), Expect = 9.975e-35
Identity = 82/262 (31.30%), Postives = 131/262 (50.00%), Query Frame = 1 
Query:  229 VFTGKTDFELIYDL-PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIY---HQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIM 1002
            V T K D E++    PNL+V+  M+ G D+L LD L  + +              ++       +D+ +E+ + L+L ++RR ++A                  G  +    +GI+GLG IG ++A +       K IY     R + +  +   Y +++E+    DFL   C LT +T+ + N      MKS++  IN +RG +V   DL +AL  G I+GAGLDV  PEPLP+ HPL  + N ++LPHI + +  TR+ M
Sbjct:   70 VLTEKIDAEVLDAAGPNLKVLSTMSVGFDHLSLDELKKRGI--------------RIGYTPEVLTDAVAELTVALLLATSRRLIEATHEAKTGGWGTWRTLWLCGHELADSTVGILGLGRIGVAIAERLKPFKVKKFIYTDVEPRPELAEMIQAEYVSMDELARRSDFLAACCALTPETQGICNKKLFSKMKSTSIFINTSRGGVVNQEDLYEALSTGRIAGAGLDVTVPEPLPTNHPLFTLKNCVILPHIASASYTTRNAM 317
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Cavefish
Match: phgdh (phosphoglycerate dehydrogenase [Source:NCBI gene;Acc:103042539])

HSP 1 Score: 98.5969 bits (244), Expect = 4.094e-22
Identity = 73/272 (26.84%), Postives = 125/272 (45.96%), Query Frame = 1 
Query:  187 KLNNTLKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQR---NKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETR 993
            +L + +KD+   V+    K   ++I    NL+V+    +GVD +D+D    K ++V+    GN  S               +E+   L+++ +R   +A  ++           +++G  +  K LGI+GLG IG+ +A +    FG++ I +      + S+       +L E+ P  D++ +  PL   T  L+N +     K    ++N  RG I+    L+ AL  G   GAGLDV   EP P   PL+   NV+  PH+G    E +
Sbjct:   52 ELISQIKDYDGLVVRSATKVTADIIASAGNLKVIGRAGTGVDNVDVDAATKKGIIVMNTPSGNTIS--------------AAELTCTLLMSLSRHVPQAAMSMKAENWDRK---KFMGAELYGKTLGIVGLGRIGKEVATRMQ-SFGVRTIGYDPITPTEVSASWGVEQMSLEELWPQCDYITVHTPLMPSTTGLLNDDSFAKCKKGVKVVNCARGGIIDEAALLRALESGQCGGAGLDVFVEEP-PKNWPLVKHPNVICCPHLGASTKEAQ 304
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Cavefish
Match: ctbp1 (C-terminal-binding protein 1 [Source:NCBI gene;Acc:103035478])

HSP 1 Score: 97.0561 bits (240), Expect = 6.962e-22
Identity = 80/273 (29.30%), Postives = 120/273 (43.96%), Query Frame = 1 
Query:  274 NLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYN--SINEYVG--INVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQ----RNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLP-SAHPLLHMNNVMVLPHIGTF----ALETRDIMLNKTLR----NLKDSLQ 1041
             LRV+  + SG D +D+       + V               N    + + T++  M LILN  RR     QAL   T   +   I E  G    +  + LGIIGLG +GQ++A +A   FG  +I++        + S        L ++L   D + + C L     HLIN   +K M+  A+L+N  RG +V    L  AL+ G I GA LDV + EP   S  PL    N++  PH   +    ++E R+    +  R     + DSL+
Sbjct:   84 GLRVIVRIGSGFDNVDVKAAAELGIAVC--------------NVPAASVEETADTSMCLILNLYRRVTWMHQALREGTRASSVEQIREVAGGAARIRGETLGIIGLGRVGQAVALRAK-AFGFGVIFYDPYLPEGVERSLGLQRMATLQDLLIHSDCVSLHCSLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHETEPFSFSQGPLKDAPNLICTPHTSWYSEQASIEAREEAAREVRRAITGRIPDSLK 341
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Sea Lamprey
Match: grhpra (glyoxylate reductase/hydroxypyruvate reductase a [Source:ZFIN;Acc:ZDB-GENE-040724-230])

HSP 1 Score: 145.206 bits (365), Expect = 7.688e-41
Identity = 88/261 (33.72%), Postives = 140/261 (53.64%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSC---LFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            P+L+V+  M+ G D+L LD    + + V +                +  +D+T+E+ + L+L ++RR ++A   + +            G  ++   +G++GLG IG ++  +    FG++ ++Y  RN K      L   +  L  +L   DF+V+SC LT+ T+ L        MK SA  INV+RG IV  +DL DAL  G I+ AGLDV  PEPLP+ HPLL ++N +++PHIG+ A++TR  M   T  NL   L+
Sbjct:   65 PSLKVISTMSVGFDHLSLDECKKRGIRVGYT--------------PDVLTDATAELTVGLLLATSRRLVEAAAEVKSGGWGTWKPMWMCGQGLSGSTVGVVGLGRIGMAVCERLKP-FGVRRVLYTGRNPKPDAERRLDAQFLPLQGLLREADFVVVSCALTDATRGLFGREAFARMKRSAVFINVSRGLIVNQDDLYDALTSGEIAAAGLDVTTPEPLPTDHPLLSLSNCVIMPHIGSAAIDTRSKMAVMTAENLLAGLR 310
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Sea Lamprey
Match: phgdh (phosphoglycerate dehydrogenase [Source:ZFIN;Acc:ZDB-GENE-030131-647])

HSP 1 Score: 85.1149 bits (209), Expect = 1.466e-18
Identity = 77/278 (27.70%), Postives = 127/278 (45.68%), Query Frame = 1 
Query:  169 INPLELKLNNTLKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQR--NKKSSCLFPYYE-NLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETR 993
            ++P EL     +KD+   ++    K   E+++    L +V    +GVD +D++    + V+V+    GN  S +++  C           GMLL L  AR   +A+ ++H          +++G  +  K LGI+GLG IG+ +A +    FGM  I +      + S  F   + +L ++ P  DF+ +  PL   T  L+N       K    ++N  RG I+  + L  AL  G   GAGLDV   EP  +   L+    V+  PH+G    E +
Sbjct:   34 MSPAELV--ECIKDYDALIVRSATKVTAEVLHAGERLLLVGRAGTGVDNVDVEAATRRGVIVMNTPGGNTMSAAEL-TC-----------GMLLCL--ARFIPQAMASMHEGKWERK---KFMGTELLGKTLGIVGLGRIGREVALRMQ-AFGMTTIGYDPIIPAEVSAAFGVEQLSLEQLWPKCDFITVHTPLMPSTTGLLNDASFARCKRGVRVVNCARGGIIDEDALQRALESGQCGGAGLDVFIQEP-KTNIALIRHPRVVCGPHLGASTHEAQ 290
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010022.1 (pep scaffold:Pmarinus_7.0:GL476399:2559852:2563746:-1 gene:ENSPMAG00000009069.1 transcript:ENSPMAT00000010022.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.7221 bits (195), Expect = 3.071e-18
Identity = 49/173 (28.32%), Postives = 88/173 (50.87%), Query Frame = 1 
Query:  148 LEESYNFINPLELKLNNTL--KDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKK 660
            +E  +  +   ++  N+ L  K   IG+  +  +   +L+  LP L+ V     GVD+LDL +L+S  V V +                +  S  T+++GM L+L SAR  +  + +L    ++      +VG++V+   LGI+G+G +G+ +A +A  GF M I+YH R ++
Sbjct:    1 IERHFKLVTLKDVMGNDDLAQKIEAIGIFYWEPRVTKDLLESLPKLKTVASAGVGVDHLDLPLLWSHGVSVSY--------------TPDVVSAPTADMGMALLLASARNLVDGV-SLTKSQMFTAKDRSFVGVDVDGATLGILGMGRVGRLVAERAR-GFRMDILYHNRTRR 157
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Yeast
Match: GOR1 (Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000005218])

HSP 1 Score: 114.39 bits (285), Expect = 2.696e-29
Identity = 84/285 (29.47%), Postives = 137/285 (48.07%), Query Frame = 1 
Query:  235 TGKTDFELIYDLPNLRVVCCMT-SGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSAR-------RTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANK-ASLGFGMKIIYHQRNK-----KSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN 1047
            TG+ D EL   LP+  V  C T +G D +D++    +++              +V N  +  S++T++  + L+L + R       R ++       P     +     G +   K +GI+GLG IG+ +  +    GF    IYH R++     +  C +  +E   E L   D + ++ PL + T HLIN   ++ MK    ++N  RG+++    + DALR G I  AGLDV + EP  S   LL M+ V+ LPH+GT ++ETR  M    + N K+ + T 
Sbjct:   68 TGRFDEELALALPSSVVAVCHTGAGYDQIDVEPFKKRHI--------------QVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEGNWPEAGP-----ACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGF-ENFIYHNRHQLPSEEEHGCEYVGFE---EFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGLDVFEYEPKISKE-LLSMSQVLGLPHMGTHSVETRKKMEELVVENAKNVILTG 328
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Yeast
Match: FDH1 (NAD(+)-dependent formate dehydrogenase; may protect cells from exogenous formate [Source:SGD;Acc:S000005915])

HSP 1 Score: 88.9669 bits (219), Expect = 3.090e-20
Identity = 80/306 (26.14%), Postives = 136/306 (44.44%), Query Frame = 1 
Query:  136 KNRVLEESYNFINPLELK------LNNTLKDH--VIGVLVFTGKTDFELIYDLPNLRVVCCMTSGV--DYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQ----------RNKKSSCLF-------PYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIG 972
            +N + E+ Y  +  ++        ++  LKD   VI    F        I + PNL++  C+T+GV  D++DL+    + + V  +   N  S+         A    + I ++LI N      +AI    +  I   + NEY   ++  K++  +G G IG  +  +       K++Y+           R  ++S LF          E L +M+   D + I+CPL   ++ L N   +  MK  AYL+N  RG+I    D+ +A++ G ++G G DV D +P P  HP   M+N     H+G
Sbjct:   34 RNFIEEQGYELVTTIDKDPEPTSTVDRELKDAEIVITTPFFPAYISRNRIAEAPNLKL--CVTAGVGSDHVDLEAANERKITVTEVTGSNVVSV---------AEHVMATI-LVLIRNYNGGHQQAINGEWD--IAGVAKNEY---DLEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYDYQELPAEAINRLNEASKLFNGRGDIVQRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPKDHPWRTMDN---KDHVG 319
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Yeast
Match: SER3 (3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase; 3PG dehydrogenase that catalyzes the first step in serine and glycine biosynthesis; also functions as an alpha-ketoglutarate reductase, converting alpha-ketoglutarate to D-2-hydroxyglutarate (D-2HG); localizes to the cytoplasm; SER3 has a paralog, SER33, that arose from the whole genome duplication [Source:SGD;Acc:S000000883])

HSP 1 Score: 87.8113 bits (216), Expect = 1.436e-19
Identity = 78/285 (27.37%), Postives = 127/285 (44.56%), Query Frame = 1 
Query:  181 ELKLNNTLKD-HVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQ-RNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAH------------PLLHMNNVMVLPHIGTFALETR 993
            E +L   +KD H IG+   T  T   ++    NL  + C   G + +DLD   S+ + V    F N              S S +E+ +  I++ AR+       LH  T  +N +       V  K LGIIG G IG  L+  A    G+ ++Y+      +         L+E+L   DF+ +  P T +T+ +++  +   MK  AY+IN +RG++V    L+ A++   I+GA LDV   EP  +               L+ + N+++ PHIG    E +
Sbjct:   91 EEELIEKIKDVHAIGIRSKTRLTS-NVLQHAKNLVCIGCFCIGTNQVDLDYATSRGIAVFNSPFSN--------------SRSVAELVIAEIISLARQLGDRSIELHTGT--WNKVAARC-WEVRGKTLGIIGYGHIGSQLSVLAE-AMGLHVLYYDIVTIMALGTARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQ 356
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Yeast
Match: SER33 (3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase; 3PG dehydrogenase that catalyzes the first step in serine and glycine biosynthesis; also functions as an alpha-ketoglutarate reductase, converting alpha-ketoglutarate to D-2-hydroxyglutarate (D-2HG); localizes to the cytoplasm; SER33 has a paralog, SER3, that arose from the whole genome duplication [Source:SGD;Acc:S000001336])

HSP 1 Score: 86.2705 bits (212), Expect = 5.356e-19
Identity = 78/285 (27.37%), Postives = 128/285 (44.91%), Query Frame = 1 
Query:  181 ELKLNNTLKD-HVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQ-RNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAH------------PLLHMNNVMVLPHIGTFALETR 993
            E +L   +KD H IG+   T  T+ +++    NL  + C   G + +DL    SK + V    F N              S S +E+ +  I++ AR+       LH  T  +N +       V  K LGIIG G IG  L+  A    G+ ++Y+      +         L+E+L   DF+ +  P T +T+ +++  +   MK  AY+IN +RG++V    L+ A++   I+GA LDV   EP  +               L+ + N+++ PHIG    E +
Sbjct:   91 EDELIEKIKDVHAIGIRSKTRLTE-KILQHARNLVCIGCFCIGTNQVDLKYAASKGIAVFNSPFSN--------------SRSVAELVIGEIISLARQLGDRSIELHTGT--WNKVAARC-WEVRGKTLGIIGYGHIGSQLSVLAE-AMGLHVLYYDIVTIMALGTARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQ 356
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Yeast
Match: YPL113C_mRNA (Glyoxylate reductase; acts on glyoxylate and hydroxypyruvate substrates; YPL113C is not an essential gene [Source:SGD;Acc:S000006034])

HSP 1 Score: 79.337 bits (194), Expect = 7.299e-17
Identity = 54/169 (31.95%), Postives = 90/169 (53.25%), Query Frame = 1 
Query:  547 VNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRN---KKSSCLF--PYYENLNE--MLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKD 1032
            +NKKVL I+G G+IGQ++ +     F M I Y++R    +KS   +   Y+ +L++       D ++++ P T  T ++IN   L   K    ++NV RG+ +  + L+DAL  G ++  GLDV   E       LL   +V  LPHIG+      D+++ +TL  L++
Sbjct:  216 MNKKVL-ILGFGSIGQNIGSNLHKVFNMSIEYYKRTGPVQKSLLDYNAKYHSDLDDPNTWKNADLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESGKVASCGLDVFKNEETRVKQELLRRWDVTALPHIGS---TVADMVIKQTLITLEN 380
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Nematostella
Match: EDO43023 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZX5])

HSP 1 Score: 181.03 bits (458), Expect = 9.212e-55
Identity = 102/261 (39.08%), Postives = 144/261 (55.17%), Query Frame = 1 
Query:  256 LIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSS----CLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNL 1026
            L+ DLP+L+V+  + +G D +D+     + +              +V N      D T+++ + L+L SAR  +        P  +  SI    G  V    LGI+GLGA+G ++A +A  GF M+I+YH R +K          +   L+E+L   DF+V+ C LT +T+HLI   +L  MKSSA LINV RG IV  +DL  AL+ G+I GA LDV +PEPLP  HPLL + NV+V PHIGT  L TR  M+   + NL
Sbjct:   17 LLDDLPSLKVISSIGAGFDRIDIPAATKRGI--------------RVGNTPGVVQDCTADMAIGLLLASARHIVTGDANTRKPG-FTKSIFNCFGTRVTGSTLGIVGLGAVGSAVAMRAK-GFKMRILYHGRTRKEGKERETGAEHCSKLDELLKESDFVVLCCALTKETRHLITAAQLSQMKSSATLINVARGGIVNHDDLTTALQNGVICGAALDVTEPEPLPHGHPLLALPNVIVTPHIGTLTLATRSAMMEMGIENL 261
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Nematostella
Match: EDO32878 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STU2])

HSP 1 Score: 169.088 bits (427), Expect = 2.491e-50
Identity = 98/269 (36.43%), Postives = 147/269 (54.65%), Query Frame = 1 
Query:  253 ELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKK----SSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN 1047
            EL+  LPNL+V+  + +G+D +DL+    + ++V     GN   IS          D  ++    L++ +AR  ++A   +  P     SI  + G  V+   LGIIGLG IG ++A +A  GF M+I+Y+ R +K    S     Y   L ++L   D++++SC LT +T+H+I    L  MK SA LINV RG +V  +DL  AL+ G+I GA LD  DPEPLP  HPLL ++N +V PHI +  L  R   +   L N+   L+ +
Sbjct:    5 ELMASLPNLKVISNIGAGIDNIDLEAAKRRGILV-----GNTPGIS----------DCLADFAWALLMAAARNVIQADAMMRKPGFKIPSIINWHGTRVSGATLGIIGLGNIGLAVAKRAK-GFDMRILYYNRTRKMKAESELGVHYCSGLKDLLKESDYVMLSCALTPETRHIIKSAELSQMKPSATLINVARGGLVNHDDLTTALQNGVIRGAALDATDPEPLPHDHPLLALSNAIVTPHIASATLHARRAYVKNALLNVNAGLRGD 257
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Nematostella
Match: EDO32867 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STU0])

HSP 1 Score: 150.599 bits (379), Expect = 1.697e-42
Identity = 108/308 (35.06%), Postives = 155/308 (50.32%), Query Frame = 1 
Query:  151 EESYNFINPLELKLNNTLKDHVIGVLVFTG--KTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSS------CLFPYY--------ENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNL 1026
            + +  FI+  E+   N  +  V G+ +  G    D  L+   P LRV+     GVD++DL     + +              +V N      + T++  + L+L SAR+       +  P     SI    G  V    LGI+GLG +G ++AN+A  GF M+I+YH R +K         L  YY          L+E+L   DF+V+ C LT++T+HLI   +L  MKSSA LINV RG +V  +DL  AL+ G+I GA LDV +PEPLP  HPLL + NV+V PH+G     T   M+   + NL
Sbjct:   28 QRNIRFISSDEVSDKN--RSRVQGLYIHAGFVVVDSALMDCYPELRVISSAGVGVDHIDLAAATIRGI--------------RVGNTPGVVQECTADHAIGLLLASARKICSGDSVIRQPGFSKESIFNSFGTKVTGSTLGIVGLGGVGSAVANRAK-GFKMRILYHNRTRKEDKELETVVLLFYYAFVGAEYCSKLDELLKESDFVVLCCALTDETRHLITAAQLSQMKSSATLINVARGGLVNHDDLTTALQNGVIRGAALDVTEPEPLPHGHPLLALPNVIVTPHVGATTFGTFIEMMQMVMDNL 318
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Nematostella
Match: EDO25400 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DWL0])

HSP 1 Score: 124.405 bits (311), Expect = 7.055e-34
Identity = 74/209 (35.41%), Postives = 111/209 (53.11%), Query Frame = 1 
Query:  421 DSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN 1047
            D  +++   L+L++AR   ++ + +             +    + K LGI G+G IG ++A +A+ GF M++ YH R         Y  +L E+    DFLVI+    + T+HL+N   L  +    +LINV RGS+V    LV AL+ G I+GAGLDV + EP P A  LL  +NV++ PHI +   ETR  M +  LRNL   + T 
Sbjct:   13 DCVADMAFALLLDAARGLSESDRFVRRGDWSRGRFG--IRTRASGKRLGIFGMGRIGSTVARRAA-GFDMEVAYHNRRPVEGSPHLYQPSLLELARWSDFLVITAAGGDGTQHLVNAEVLDALGPQGFLINVARGSVVDEAALVQALQQGRIAGAGLDVFEDEPRPHAE-LLSQDNVVLAPHIASGTHETRRAMADLVLRNLAQFIATG 217
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Nematostella
Match: EDO47853 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL06])

HSP 1 Score: 123.635 bits (309), Expect = 2.576e-32
Identity = 85/276 (30.80%), Postives = 137/276 (49.64%), Query Frame = 1 
Query:  226 LVFTGKTDFELIYDL-PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPYYENL--------NEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNL 1026
            ++ T K D EL+    P LRVV  M+ G D++    L ++N+ + +                N  +D+T+ + + L+L ++RR ++A+  + N            G  +    +GI+GLG IG ++A +  L FG+  I +   K +    P  E          + +    DF++    LT++T+ + N +    MKS+A  +N +RG +V  +DL DAL+   I  AGLDV  PEPLP+ H LL + N ++LPHIG+    TR  M     RNL
Sbjct:   73 VLLTEKVDAELLDAAGPQLRVVSTMSVGYDHVTTKELKNRNIPLGYT--------------PNVLTDATATLTVALLLATSRRLIEAVGEVKNGGWSTWKPMWMCGATLRGSTVGIVGLGRIGLAVAQRL-LPFGVSKIVYSGWKAT----PEVEKQVNATHVDNDALFAKSDFVLGCTALTSETQGMFNKDAFSKMKSTAIFVNTSRGGVVNQDDLYDALKDNAIRAAGLDVTVPEPLPTDHKLLSLPNCVILPHIGSAEDATRTEMATLAARNL 329
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Medaka
Match: ENSORLT00000022747.2 (probable 2-ketogluconate reductase [Source:NCBI gene;Acc:101169325])

HSP 1 Score: 163.31 bits (412), Expect = 6.875e-47
Identity = 103/275 (37.45%), Postives = 153/275 (55.64%), Query Frame = 1 
Query:  232 FTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSS-----CLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            F    + EL+  LP+L+VV     GVD+LD+  + S  V              KV N     SDST+++ M L+L SARR L+  Q   +P          +G+ V    LGIIG+G IG  +A +A  GF MKI+YH R ++S+         + E+L+E+L   DF++++  LT +T+ LI    L +MK +A L+N++RG +V  N LVDAL+ G I  A LDV  PEPLP  HPLL + +V++ PHIG     T   M+ + +RN + +++
Sbjct:   58 FCPVVEPELLRLLPSLKVVASGGVGVDHLDVPFINSLGV--------------KVANTPGVVSDSTADLAMALLLASARRILEGHQVAIDPKTVLIP-QRLMGVEVTNASLGIIGMGEIGHKIAQRAK-GFDMKIVYHNRRRRSAEDERAVGAKFCESLDELLGRSDFVMVAVKLTAETRGLIGHRELSIMKPTATLVNISRGQVVDQNALVDALQSGRIRAAALDVTHPEPLPRDHPLLGLPSVLITPHIGINTFTTARRMVERMVRNARAAVE 316
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Medaka
Match: zgc:136493 (probable 2-ketogluconate reductase [Source:NCBI gene;Acc:101168130])

HSP 1 Score: 150.599 bits (379), Expect = 4.541e-42
Identity = 91/247 (36.84%), Postives = 138/247 (55.87%), Query Frame = 1 
Query:  256 LIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFP-------YYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGT 975
            L+  LP+L+VV     G+D+LD+  + S  V              KV N     S +T+++ M L+L SAR+ ++      +P   Y   +  +G+ V+   LGIIG+G IG  +A +   GF M+I+YH R ++  CL         Y  N++++L   DF+V++  L+ +TKHLI    L LMK +A L+N++RG +V    L+ AL+ G+I  A LDV  PEPLP  HPLL + NV++ PH GT
Sbjct:   65 LLTSLPSLKVVANGGVGIDHLDVSYINSLGV--------------KVTNTPGVVSAATADMAMGLLLASARKIVEGHLISVDPKTTYLP-SSLMGVEVSGSTLGIIGMGNIGYKIAQRGK-GFDMRILYHNRTRR--CLEDEEAVGAIYCRNMDDLLKESDFVVLAVNLSPETKHLIGHRELALMKDTATLVNISRGLVVDQEALLKALQSGVIQAAALDVTYPEPLPRDHPLLSLPNVLLTPHAGT 293
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Medaka
Match: zgc:136493 (probable 2-ketogluconate reductase [Source:NCBI gene;Acc:101168130])

HSP 1 Score: 149.828 bits (377), Expect = 2.025e-41
Identity = 91/247 (36.84%), Postives = 138/247 (55.87%), Query Frame = 1 
Query:  256 LIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFP-------YYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGT 975
            L+  LP+L+VV     G+D+LD+  + S  V              KV N     S +T+++ M L+L SAR+ ++      +P   Y   +  +G+ V+   LGIIG+G IG  +A +   GF M+I+YH R ++  CL         Y  N++++L   DF+V++  L+ +TKHLI    L LMK +A L+N++RG +V    L+ AL+ G+I  A LDV  PEPLP  HPLL + NV++ PH GT
Sbjct:  106 LLTSLPSLKVVANGGVGIDHLDVSYINSLGV--------------KVTNTPGVVSAATADMAMGLLLASARKIVEGHLISVDPKTTYLP-SSLMGVEVSGSTLGIIGMGNIGYKIAQRGK-GFDMRILYHNRTRR--CLEDEEAVGAIYCRNMDDLLKESDFVVLAVNLSPETKHLIGHRELALMKDTATLVNISRGLVVDQEALLKALQSGVIQAAALDVTYPEPLPRDHPLLSLPNVLLTPHAGT 334
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Medaka
Match: grhpra (glyoxylate reductase/hydroxypyruvate reductase [Source:NCBI gene;Acc:101154959])

HSP 1 Score: 145.591 bits (366), Expect = 3.869e-40
Identity = 94/272 (34.56%), Postives = 144/272 (52.94%), Query Frame = 1 
Query:  271 PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSCLFPYYENLN-EMLPL------VDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN*YCSE 1062
            PNL+V+  M+ G D+L L  +  + +              +V    +  +D+T+E+ + L+L ++RR  + ++ + +            G  ++   +GIIGLG IG ++A +  L FG+K ++Y  R  KS     Y   +N E +PL       DF+V+SC LT +T+ L +      MK +A  IN +RG++V   DL DAL  G I+ AGLDV  PEPLP+ HPLL + N +VLPHIG+    TR +M     +NL   LQ +   SE
Sbjct:   74 PNLKVISTMSVGFDHLVLSEIKKRGI--------------RVGYTPDVLTDATAELTVALLLATSRRLPEGVEEVKSGGWSSWKPLWLCGYGLSGSTVGIIGLGRIGMAIAQRL-LPFGVKRLLYSGRTAKS-----YAAEVNGEFVPLDTLTSESDFIVVSCSLTPETQGLCDKAFFSKMKKNAIFINSSRGAVVNQEDLYDALSSGQIAAAGLDVTTPEPLPTNHPLLTLKNCVVLPHIGSATYSTRGVMSALAAQNLLGGLQGSDMPSE 325
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Medaka
Match: grhprb (glyoxylate reductase/hydroxypyruvate reductase [Source:NCBI gene;Acc:101163636])

HSP 1 Score: 135.961 bits (341), Expect = 2.340e-36
Identity = 84/262 (32.06%), Postives = 132/262 (50.38%), Query Frame = 1 
Query:  229 VFTGKTDFELIYDL-PNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQ---RNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIM 1002
            V T K D EL+    PNL+V+  M+ G D+L LD L  + +              +V       +D+ +E+ + L+L ++RR ++A                  G  +    +GI+GLG IG ++A + +     K IY     R + +  +   Y + +E+    DFL + C LT +TK + N      MK+++  IN +RG +V   DL +AL  G I+GAGLDV  PEPLP+ HPL  + N ++LPHI + +  TR+ M
Sbjct:   89 VLTEKIDAELLDSAGPNLKVLSTMSVGFDHLSLDELKKRGI--------------RVGYTPEVLTDAVAELTVALLLTTSRRLIEATHEAKTGGWGTWRTLWLCGHELANSTVGILGLGRIGVAIAERLAPFKVKKFIYTDVAPRPELARAINAEYVSFDELAKQSDFLAVCCALTPETKEICNKELFSKMKNTSIFINTSRGGVVNQEDLYEALAAGQIAGAGLDVTVPEPLPTNHPLFTLKNCVILPHIASASYTTRNAM 336
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Planmine SMEST
Match: SMESG000080490.1 (SMESG000080490.1)

HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0
Identity = 301/326 (92.33%), Postives = 302/326 (92.64%), Query Frame = 1 
Query:   70 MSNYLQPTILLIGFDSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN 1047
            MSNYLQPTILLIGFDSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVIGVLVFT KTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVV              KNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTR         VDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLN+TLRNLKDSLQTN
Sbjct:    1 MSNYLQPTILLIGFDSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVIGVLVFTWKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVV--------------KNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTR---------VDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNQTLRNLKDSLQTN 303
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Planmine SMEST
Match: SMESG000080490.1 (SMESG000080490.1)

HSP 1 Score: 590.882 bits (1522), Expect = 0.000e+0
Identity = 300/326 (92.02%), Postives = 301/326 (92.33%), Query Frame = 1 
Query:   70 MSNYLQPTILLIGFDSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVIGVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN 1047
            MSNYLQPTILLIGFDSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVIGVLVFT KTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVV              KNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTR          DALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLN+TLRNLKDSLQTN
Sbjct:    1 MSNYLQPTILLIGFDSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVIGVLVFTWKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVV--------------KNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTR----------DALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNQTLRNLKDSLQTN 302
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Planmine SMEST
Match: SMESG000004379.1 (SMESG000004379.1)

HSP 1 Score: 141.739 bits (356), Expect = 7.808e-39
Identity = 87/276 (31.52%), Postives = 142/276 (51.45%), Query Frame = 1 
Query:  241 KTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSCLFPYYEN--------LNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQ 1041
            K   E I    NL+V+  M+ G D+++      +N+              ++       +D+T+E+ + L+L+ +RR ++ + ++   T          G  +   V+GI+GLG+IG+++A + +  FG+K ++     K    L    E+         +E++   DF+++SC L   TK L N      MK +A LIN++RG +V  + L  AL  G I+GAGLDV  PEPLP  HPLL + N ++LPHIG+  +ETR+ M    + NL   LQ
Sbjct:   56 KISDEFINSSKNLKVISTMSVGFDHINQSAAQKRNI--------------RIGYTPEVLTDATAELAIGLLLSVSRRLIEGVNSVRGGTWGAWKPFWMCGYGLKDSVVGIVGLGSIGKAIAKRVN-SFGVKKLLASGSEKPKDKLIVEIESKVLVNKVCFDELIACSDFIIVSCSLNENTKDLFNEKAFDKMKKNAILINISRGPVVNQDSLCKALIEGKIAGAGLDVCYPEPLPIDHPLLKLTNCIILPHIGSATIETRNEMCKVAVENLIKGLQ 316
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Planmine SMEST
Match: SMESG000004374.1 (SMESG000004374.1)

HSP 1 Score: 140.584 bits (353), Expect = 1.641e-38
Identity = 82/284 (28.87%), Postives = 147/284 (51.76%), Query Frame = 1 
Query:  232 FTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRN-------KKSSCLFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRDIMLNKTLRNLKDSLQTN*YCSE 1062
             + K D   I    NL+++  M+ G D++D+   + KN+              K+     +  D+ +E+ + L+L  +RR L+ I+A+ + +          G+ +   V+G++G G IG+ +A + +  FG+K +            K    +  +  +  E+L   DF++++C L ++T+H+ N      MK +A L+N++RG ++  + L+ AL    I+GAGLDV  PEP+P+ HPLL + N ++LPH+G+   ETR+ M +  + NL   LQ     SE
Sbjct:   52 LSDKIDEHFINSTKNLKLIVTMSVGFDHIDVTAAHQKNI--------------KIGYTPGDLGDAIAELAIGLLLTVSRRLLEGIKAVSSGSWTTWKPFWLCGVELRNSVVGVVGFGNIGRGIAKRVN-AFGVKSVIASDKPGGPTEVKIEPNVLVHIVSFYELLEKSDFVIVACNLNDKTRHMFNEAAFGKMKRNAILVNISRGPVIDQDALLKALTEKKIAGAGLDVCVPEPIPTDHPLLKLPNCVILPHLGSATFETRNEMCHVAIDNLIKGLQGKDMPSE 320
[Close]
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Planmine SMEST
Match: SMESG000004379.1 (SMESG000004379.1)

HSP 1 Score: 135.576 bits (340), Expect = 1.835e-36
Identity = 81/257 (31.52%), Postives = 135/257 (52.53%), Query Frame = 1 
Query:  253 ELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEFGNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYNSINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMK-IIYHQRNKKSSCLFPYYEN--------LNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVTRGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHIGTFALETRD 996
            E I    NL+V+  M+ G D+++      +N+              ++       +D+T+E+ + L+L+ +RR ++ + ++   T          G  +   V+GI+GLG+IG+++A + +  FG+K ++     K    L    E+         +E++   DF+++SC L   TK L N      MK +A LIN++RG +V  + L  AL  G I+GAGLDV  PEPLP  HPLL + N ++LPHIG+  +ETR+
Sbjct:   60 EFINSSKNLKVISTMSVGFDHINQSAAQKRNI--------------RIGYTPEVLTDATAELAIGLLLSVSRRLIEGVNSVRGGTWGAWKPFWMCGYGLKDSVVGIVGLGSIGKAIAKRVN-SFGVKKLLASGSEKPKDKLIVEIESKVLVNKVCFDELIACSDFIIVSCSLNENTKDLFNEKAFDKMKKNAILINISRGPVVNQDSLCKALIEGKIAGAGLDVCYPEPLPIDHPLLKLTNCIILPHIGSATIETRN 301
The following BLAST results are available for this feature:
BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GRHPR6.202e-3933.20glyoxylate and hydroxypyruvate reductase [Source:H... [more]
GRHPR7.389e-3232.31glyoxylate and hydroxypyruvate reductase [Source:H... [more]
PHGDH5.203e-2430.71phosphoglycerate dehydrogenase [Source:HGNC Symbol... [more]
PHGDH6.061e-2430.31phosphoglycerate dehydrogenase [Source:HGNC Symbol... [more]
PHGDH9.022e-2430.71phosphoglycerate dehydrogenase [Source:HGNC Symbol... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
C31C9.21.960e-2126.82pep chromosome:WBcel235:II:13636929:13638480:-1 ge... [more]
ctbp-11.608e-1427.24C-terminal-binding protein 1 [Source:UniProtKB/Sw... [more]
ctbp-12.257e-1427.24C-terminal-binding protein 1 [Source:UniProtKB/Sw... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG316734.709e-3733.20gene:FBgn0051673 transcript:FBtr0081422[more]
CG316731.985e-3533.20gene:FBgn0051673 transcript:FBtr0339562[more]
CG316741.869e-3431.52gene:FBgn0051674 transcript:FBtr0339563[more]
CG316741.869e-3431.52gene:FBgn0051674 transcript:FBtr0081423[more]
CG93318.178e-3328.99gene:FBgn0032889 transcript:FBtr0339560[more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zgc:1364938.422e-4536.36zgc:136493 [Source:ZFIN;Acc:ZDB-GENE-060512-216][more]
grhpra5.555e-3833.46glyoxylate reductase/hydroxypyruvate reductase a [... [more]
grhprb1.463e-3633.21glyoxylate reductase/hydroxypyruvate reductase b [... [more]
grhprb1.463e-3633.21glyoxylate reductase/hydroxypyruvate reductase b [... [more]
grhprb3.099e-3632.96glyoxylate reductase/hydroxypyruvate reductase b [... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
psmd37.747e-4736.94proteasome 26S subunit, non-ATPase 3 [Source:Xenba... [more]
psmd31.634e-4637.36proteasome 26S subunit, non-ATPase 3 [Source:Xenba... [more]
grhpr.22.527e-3933.47glyoxylate reductase/hydroxypyruvate reductase, ge... [more]
grhpr.22.926e-3933.47glyoxylate reductase/hydroxypyruvate reductase, ge... [more]
grhpr.24.359e-3933.47glyoxylate reductase/hydroxypyruvate reductase, ge... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Grhpr3.917e-3931.86glyoxylate reductase/hydroxypyruvate reductase [So... [more]
Grhpr2.626e-2731.82glyoxylate reductase/hydroxypyruvate reductase [So... [more]
Phgdh1.838e-2229.533-phosphoglycerate dehydrogenase [Source:MGI Symbo... [more]
Ctbp16.277e-2027.76C-terminal binding protein 1 [Source:MGI Symbol;Ac... [more]
Ctbp11.511e-1927.76C-terminal binding protein 1 [Source:MGI Symbol;Ac... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|B2VCD1|GHRB_ERWT99.347e-4936.40Glyoxylate/hydroxypyruvate reductase B OS=Erwinia ... [more]
sp|Q8FCF1|GHRB_ECOL63.866e-4531.38Glyoxylate/hydroxypyruvate reductase B OS=Escheric... [more]
sp|A4W577|GHRB_ENT387.514e-4530.61Glyoxylate/hydroxypyruvate reductase B OS=Enteroba... [more]
sp|B1IZP1|GHRB_ECOLC8.090e-4531.08Glyoxylate/hydroxypyruvate reductase B OS=Escheric... [more]
sp|B1LJB3|GHRB_ECOSM9.781e-4531.08Glyoxylate/hydroxypyruvate reductase B OS=Escheric... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G3VP781.402e-5437.05Uncharacterized protein OS=Sarcophilus harrisii OX... [more]
A0A0L8HYA26.348e-5335.71Uncharacterized protein OS=Octopus bimaculoides OX... [more]
A0A4X2M0458.184e-5336.39Uncharacterized protein OS=Vombatus ursinus OX=291... [more]
F7DDZ39.817e-5335.84Uncharacterized protein OS=Monodelphis domestica O... [more]
A0A093I9422.347e-5239.48Uncharacterized protein (Fragment) OS=Struthio cam... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zgc:1364934.312e-4838.65probable 2-ketogluconate reductase [Source:NCBI ge... [more]
grhpra1.243e-4134.46glyoxylate and hydroxypyruvate reductase [Source:N... [more]
grhprb9.975e-3531.30glyoxylate reductase/hydroxypyruvate reductase b [... [more]
phgdh4.094e-2226.84phosphoglycerate dehydrogenase [Source:NCBI gene;A... [more]
ctbp16.962e-2229.30C-terminal-binding protein 1 [Source:NCBI gene;Acc... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
grhpra7.688e-4133.72glyoxylate reductase/hydroxypyruvate reductase a [... [more]
phgdh1.466e-1827.70phosphoglycerate dehydrogenase [Source:ZFIN;Acc:ZD... [more]
ENSPMAT00000010022.13.071e-1828.32pep scaffold:Pmarinus_7.0:GL476399:2559852:2563746... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
GOR12.696e-2929.47Glyoxylate reductase; null mutation results in inc... [more]
FDH13.090e-2026.14NAD(+)-dependent formate dehydrogenase; may protec... [more]
SER31.436e-1927.373-phosphoglycerate dehydrogenase and alpha-ketoglu... [more]
SER335.356e-1927.373-phosphoglycerate dehydrogenase and alpha-ketoglu... [more]
YPL113C_mRNA7.299e-1731.95Glyoxylate reductase; acts on glyoxylate and hydro... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO430239.212e-5539.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO328782.491e-5036.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO328671.697e-4235.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO254007.055e-3435.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8... [more]
EDO478532.576e-3230.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000022747.26.875e-4737.45probable 2-ketogluconate reductase [Source:NCBI ge... [more]
zgc:1364934.541e-4236.84probable 2-ketogluconate reductase [Source:NCBI ge... [more]
zgc:1364932.025e-4136.84probable 2-ketogluconate reductase [Source:NCBI ge... [more]
grhpra3.869e-4034.56glyoxylate reductase/hydroxypyruvate reductase [So... [more]
grhprb2.340e-3632.06glyoxylate reductase/hydroxypyruvate reductase [So... [more]
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BLAST of Glyoxylate/hydroxypyruvate reductase B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000080490.10.000e+092.33SMESG000080490.1[more]
SMESG000080490.10.000e+092.02SMESG000080490.1[more]
SMESG000004379.17.808e-3931.52SMESG000004379.1[more]
SMESG000004374.11.641e-3828.87SMESG000004374.1[more]
SMESG000004379.11.835e-3631.52SMESG000004379.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006344 ID=SMED30006344|Name=Glyoxylate/hydroxypyruvate reductase B|organism=Schmidtea mediterranea sexual|type=transcript|length=1117bp
AATGTAATCTTAATATAATTGAGCATAATAATTCAGATACTACGTTTGTT
TTAACTAATTTGAATTTCGATGTCTAATTATTTGCAACCTACTATATTGT
TAATTGGATTTGATTCTTTACTTTCAGAATCTTCCAAAAATCGAGTTTTA
GAAGAATCATACAACTTCATAAATCCTTTAGAATTAAAACTTAATAATAC
TCTTAAAGATCATGTAATTGGTGTTCTTGTTTTTACTGGGAAAACGGATT
TTGAACTGATTTATGATTTGCCTAATCTTCGGGTTGTATGTTGTATGACT
TCAGGTGTTGATTATTTAGATTTAGATGTATTATATTCTAAAAATGTTGT
GGTAATTTTTATCGAGTTTGGTAATTTTTTTAGTATATCTAAGGTAAAAA
ATTGTTCCAATGAAGCATCTGATTCGACGTCAGAAATTGGAATGCTATTA
ATTTTGAATTCTGCACGAAGAACTCTTAAAGCAATCCAAGCTTTGCATAA
TCCAACAATTTATTATAATTCTATTAATGAATATGTTGGTATTAATGTCA
ATAAGAAAGTTCTGGGTATAATTGGTTTGGGAGCTATTGGACAAAGCCTA
GCTAACAAGGCTTCCTTGGGATTTGGAATGAAAATTATTTACCACCAGAG
AAATAAAAAATCCAGTTGTCTGTTTCCTTATTATGAGAATCTAAATGAAA
TGCTACCATTAGTGGATTTCCTTGTCATATCGTGCCCTCTTACGAATCAA
ACTAAACATCTTATTAATATGAATAGGTTAAAGCTTATGAAATCCTCTGC
TTATTTAATTAATGTTACTAGAGGTTCAATTGTAAAAACGAATGATTTAG
TAGATGCTTTGAGATGTGGAATTATTTCTGGAGCTGGTCTTGATGTAGTT
GATCCTGAACCATTGCCAAGTGCGCATCCTTTGTTACATATGAATAATGT
AATGGTTCTTCCTCATATTGGAACTTTTGCTTTAGAAACACGAGATATAA
TGCTTAATAAAACTTTGAGAAACTTGAAAGATTCTTTGCAGACTAACTGA
TATTGTAGTGAACCCTTAATTGATATACATTATTTATATGAACTTGTTAA
ATTTTGAAATTTCCTCT
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protein sequence of SMED30006344-orf-1

>SMED30006344-orf-1 ID=SMED30006344-orf-1|Name=SMED30006344-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=327bp
MSNYLQPTILLIGFDSLLSESSKNRVLEESYNFINPLELKLNNTLKDHVI
GVLVFTGKTDFELIYDLPNLRVVCCMTSGVDYLDLDVLYSKNVVVIFIEF
GNFFSISKVKNCSNEASDSTSEIGMLLILNSARRTLKAIQALHNPTIYYN
SINEYVGINVNKKVLGIIGLGAIGQSLANKASLGFGMKIIYHQRNKKSSC
LFPYYENLNEMLPLVDFLVISCPLTNQTKHLINMNRLKLMKSSAYLINVT
RGSIVKTNDLVDALRCGIISGAGLDVVDPEPLPSAHPLLHMNNVMVLPHI
GTFALETRDIMLNKTLRNLKDSLQTN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005886plasma membrane
Vocabulary: molecular function
TermDefinition
GO:0016618hydroxypyruvate reductase activity
GO:0051287NAD binding
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016491oxidoreductase activity
GO:0030267glyoxylate reductase (NADP) activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR036291NAD(P)-bd_dom_sf
IPR006140D-isomer_DH_NAD-bd
IPR016040NAD(P)-bd_dom
IPR006139D-isomer_2_OHA_DH_cat_dom
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
GO:0008152metabolic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.40.50.720coord: 44..320
e-value: 1.7E-69
score: 236.0
NoneNo IPR availableGENE3DG3DSA:3.40.50.720coord: 117..304
e-value: 1.7E-69
score: 236.0
NoneNo IPR availablePANTHERPTHR10996:SF212ZGC:136493coord: 51..324
NoneNo IPR availablePANTHERPTHR109962-HYDROXYACID DEHYDROGENASE-RELATEDcoord: 51..324
NoneNo IPR availableSUPERFAMILYSSF52283Formate/glycerate dehydrogenase catalytic domain-likecoord: 40..171
IPR006140D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domainPFAMPF028262-Hacid_dh_Ccoord: 126..301
e-value: 1.8E-51
score: 174.0
IPR006139D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domainPFAMPF003892-Hacid_dhcoord: 40..324
e-value: 8.8E-7
score: 29.8
IPR036291NAD(P)-binding domain superfamilySUPERFAMILYSSF51735NAD(P)-binding Rossmann-fold domainscoord: 119..301