Nuclear pore complex protein Nup133

Overview
NameNuclear pore complex protein Nup133
Smed IDSMED30006342
Length (bp)3791
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Nuclear pore complex protein Nup133 (SMED30006342) t-SNE clustered cells

Violin plots show distribution of expression levels for Nuclear pore complex protein Nup133 (SMED30006342) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Nuclear pore complex protein Nup133 (SMED30006342) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Nuclear pore complex protein Nup133 (SMED30006342) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006342

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30006342SMESG000034820.1 SmedASXL_000839SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30006342SMESG000034820.1 dd_Smed_v4_5977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006342SMESG000034820.1 Contig53439newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006342SMESG000034820.1 Contig53439uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Human
Match: NUP133 (nucleoporin 133 [Source:HGNC Symbol;Acc:HGNC:18016])

HSP 1 Score: 110.153 bits (274), Expect = 1.329e-23
Identity = 156/692 (22.54%), Postives = 294/692 (42.49%), Query Frame = 1 
Query: 1684 VMEIIKEIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQ---IMTNTQCQEIETIFSKTCQKNSFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENI---PPEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESIIN---LIINLVDFARNSDCDEIF-ESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKY-IVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWK---------EITEDSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            V +I  +++D++P  DPRW +++    ++   + N +LI+  QL  K +A     L+   +    FG +G+ P     R   M    A RL +   C+ +  L   + L         ++N    I  N +  EI +              LT  ++  ++VS + T     CE L         +E+ E +    P  S    ++      IL + L+A+  YR+   S +       S        P W     P G+   II    +++ +     +S+   I  E ++ ++  +L+ +  +++ ++  S N+   ++L   Y   R DL++ ++  G+ +     L++K+ DF  ++ +C+  DN S+      L+ Y+ ++ D  FS+F+  WY EK K   + ++                                  +  FL   E  +  WLHEI  +   +A  TL  L   +    + KKT L L+KL+ LAS  D S +  +  I  + E   ++  QE +P  ++    +  ++S+ P+L   QLI LY+     EN  + +Y   +AL+LL +  + + +          N+L + I     LQ +NW          E+++DSI       ++   ++ GI + + LPE+ DL   + +  +  +   E+++K +YE
Sbjct:  561 VTQISVDLMDDYPASDPRWAESVP---EEAPGFSNTSLIILHQLEDKMKA--HSFLMDFIHQVGLFGRLGSFP----VRGTPM----ATRLLL---CEHAEKLSAAIVLKNHHSRLSDLVNTAILIALNKREYEIPS-------------NLTPADVFFREVSQVDTI----CECL---------LEHEEQVLRDAPMDSIEWAEVVINVNNILKDMLQAASHYRQNRNSLYRREE---SLEKEPEYVP-WTATSGPGGIRTVIIRQHEIVLKVAYPQADSNLRNIVTEQLVALIDCFLDGYVSQLKSVD-KSSNRERYDNLEMEYLQKRSDLLSPLLSLGQYL-WAASLAEKYCDFDILVQMCEQTDNQSR------LQRYMTQFADQNFSDFLFRWYLEKGKRGKLLSQPISQHGQ---------------------------LANFLQAHE--HLSWLHEINSQELEKAHATLLGLANMETRYFAKKKTLLGLSKLAALAS--DFSEDMLQEKIEEMAEQERFLLHQETLPEQLLAE--KQLNLSAMPVLTAPQLIGLYIC---EENRRANEYDFKKALDLLEYIDEEEDIN--------INDLKLEILCKA-LQRDNWSSSDGKDDPIEVSKDSI----FVKILQKLLKDGIQLSEYLPEVKDLLQADQLGSLKSNPYFEFVLKANYE 1149
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Fly
Match: Nup133 (gene:FBgn0039004 transcript:FBtr0084302)

HSP 1 Score: 69.707 bits (169), Expect = 1.548e-11
Identity = 106/495 (21.41%), Postives = 215/495 (43.43%), Query Frame = 1 
Query: 2302 ILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESIINLIINLVDFARNSDC-------DEIFESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLS-LAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKYIVR-ALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITEDS----INSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYETLTADFKKSSPLPMEI 3747
            I+ + L     YRK+  S+F     S     +    P W       GV +++  LI   V +   S C        ++++ + +++ + L+    R  +++S  + + +   L + +   R +LI+ +++D +  E   K+++K++DF  ++ +CD   +      K  LE Y  KY +  FS+F +NW+  + +   +                 +R +                + +F+   +  +  W+  I    F +AA  L +L + +   ++ KK+ LS     +  A+E DL+     + +  I+  L  +++Q  +  +V++S     D + Q +L+ E++I LY+A    EN+ + +   R ALELLS+  Q   ++               IW   I + +NW +   ++    +   +   +I  +   G D   +LP M+D      + ++ Q    +YL+K +YE +   FK+  P  ME+
Sbjct:  778 IVLDVLGQVFKYRKQHASSF---RLSHEKLPSYENLP-WTAMAGSAGVRDTLTRLIDISVRYG--SHCVSETELKQQLYQQIFELIDLVLD---GRKTYLKSVRDTE-KFNVLQQQFEAQRRELISVLIKD-RQYEYAAKIAEKYLDFQSLVLICDETQD------KERLEDYTRKYEEYDFSQFAINWHLRQNRHGEV----------------FERFKGNQT-----------ALAQFM--RDHPSLGWIQLIFNGDFERAAKVLYELAQCETEFVARKKSMLSLAKLAAFAAAESDLT-----AQVEKINADLTLVEYQSQLGHDVLESF--GFDPAEQKVLKAEEIISLYIA---EENETASETEFRKALELLSYVEQPYDMRH-------------KIWCAAI-KRDNWTDYDPNNAVHYMQKLLFYKIIEISQLMGNDSENVLPPMEDFLESVELGDLPQQKPFQYLLKLTYEYVADMFKQ--PDDMEL 1200
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Zebrafish
Match: nup133 (nucleoporin 133 [Source:NCBI gene;Acc:406852])

HSP 1 Score: 85.8853 bits (211), Expect = 2.369e-16
Identity = 100/437 (22.88%), Postives = 186/437 (42.56%), Query Frame = 1 
Query: 2437 IGVSESIINLIINLVDFARNSDCDEIFESVL--DVVAVYLNFFKHRIEWMES--HSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDIS--SQPILRVEQLIKLYLASAKSENDCSVKY-IVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITE---------DSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            +G   S+I+    L+  A     D    SVL   +VA+  +     +  + S      Q   + L   Y   R +L+  ++E G++ +    L++K+ DF  ++ LC+  DN S+      L+ Y+ K+ D  F++F+  WY EK K   + ++     +                            +  FL   +  +  WLH+I V+ + +A  TL      +    S KKT L+L+KL+ LAS  D+        +N I E   ++  QE +P    K +LE K ++  S P+L  + LI LY+     EN  + +Y   +AL+LL +  +   +     K +        I+S  +  + +WKE            ++   +    ++   I+  + +   LP++ DL   + ++ +      E+L++ +YE
Sbjct:  748 VGGVRSVISRQHELILRAAYPHADAELRSVLCEQLVALLDSLLSGYVAQLTSLRRGGQQERYDTLENEYTQKRSELLKPLLELGQH-QWVAALAEKYCDFDILVQLCERTDNQSR------LQQYMVKFADQNFADFLFRWYMEKGKRGKLLSQPMATHQQ---------------------------LASFLQAHD--HLSWLHDIHVQDYQRAHRTLYNQANMETRYFSKKKTLLALSKLTALAS--DMPEPVHRRQLNDIVEQERFLLHQETLP----KQLLEEKQLNPDSMPLLSPQNLISLYIC---DENRGANEYDFKKALDLLEYFEEENGIDVDALKRE--------IFSKAL--KKDWKESWSSSDDNDDPLEAARDSTFVKILQKLIQERVSLQTYLPDIKDLLQEDELESLKSKPYFEFLLRANYE 1129

HSP 2 Score: 52.7582 bits (125), Expect = 3.145e-6
Identity = 34/135 (25.19%), Postives = 63/135 (46.67%), Query Frame = 1 
Query:   64 SRISNSYIFKDFNNGMFKVHSFGQGLHNKITESLK--NCGDQSKIRL-INDHMLVINRNSMLIWKYIFFQKNTISACKEYFLPNSEIEYSAN------QGMIIYDQTNKKSCIVVGDDAIVRFWPDIGYPNEYID 441
            +R+ +  + + +N   F V +FG  L  K+ E+L   +  DQ  +++  +    ++    +++WK        +S CK+  LP+SE  YSA+       G +        S + V  D +VRFWP + +   Y +
Sbjct:   47 TRVQSHAVVESYN---FDVQTFGSSLPVKVMEALTMADVDDQISVKVEASGWAWMVCGERLIVWKVSQTSVAKLSVCKDLQLPSSEFAYSADLVSISSSGPLDLAPIQSISVLAVSPDGLVRFWPSLAHEGSYTE 178
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Xenopus
Match: NUP133 (nucleoporin 133kDa [Source:NCBI gene;Acc:100494693])

HSP 1 Score: 82.0333 bits (201), Expect = 5.608e-15
Identity = 89/345 (25.80%), Postives = 156/345 (45.22%), Query Frame = 1 
Query: 2701 LSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLAS--EQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYK--DISSQPILRVEQLIKLYLA---SAKSENDCSVKYIVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNW--KEITEDSINST---VMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            L++K+ DF  ++ +C+  DN S+      L+ Y+  + D  FS+F+  WY EK K                          G + S+  + +  L +  FL   E  +  WLHE+  + F +A  TL  L   +      KKT L L+KL+ LAS  ++D+ +E+ E     I E  H++  QE +P    K +LE K  D+++ P+L   +LI+LY+       +END       +AL+LL +         G+    +   L + I    + + + W   +  +D I +T   +   V+   +  GI++   LPE + L   + +  +  +   E+ +K +YE
Sbjct:  848 LAEKYCDFDILVQICEMTDNQSR------LQRYMTLFSDQNFSDFLFRWYLEKGKR-------------------------GKLLSQPASQHGQLAV--FLQAHE--HLSWLHEVNSQEFEKAHRTLHTLANMETRYFCKKKTLLGLSKLAALASDFQEDILQEKVEE----IAEQEHFLLHQETLP----KQLLEEKQLDLNTMPVLSPIELIQLYICEENKRANEND-----FKKALDLLEYI--------GDDSEVDIEELKLEILCKAV-KRDEWCATDGKDDPIEATKESIFVKVLQNLLNKGIELKSYLPEAETLLQSDELSSLKTNSYFEFSLKANYE 1135

HSP 2 Score: 54.6842 bits (130), Expect = 1.304e-6
Identity = 54/226 (23.89%), Postives = 99/226 (43.81%), Query Frame = 1 
Query:  112 FKVHSFGQGLHNKITESLKNCG-DQSKIRLINDH--MLVINRNSMLIWKYIFFQKNTISACKEYFLPNSEIEYSANQGMIIYDQTNKKSCIVVG-----DDAIVRFWPDIGYPNEYIDQRIPNIYNDSCILIERVYDNVLIFVFKSMKFIIADLKDFADAGISFKQFSQPTGFINGIRSCLSSFF-VTNANQESSFINIKISTNLSEETTEMFILFDNNIDCLSLD 762
            + V  FG  L  K+ E+L N G D+     I++     +  ++ ++IWK        +  CKE  LP S+ E+SA+   I     +  +   V       +   R+WP+I + + YI+    +  +  C  +  V  N   F+  S K  +  L   A   I+ +   Q  G ++GI   +S+ F + +   ES+  ++     L ++    + L D++I+   LD
Sbjct:   73 YNVQLFGSSLPVKVMEALSNSGVDEPLAARIHEGGWAWLACKDRLIIWKISHSTSAKLMVCKELPLPLSDSEWSADLADICAHTGDSAAGQAVALMAATPEGSARYWPNILHESNYIES-YADFGSSLCAFVTAVKGNS--FILSSEKNHLVRLTPDASGKINQRILPQGQGMLSGIGRRVSTLFGILSPAVESTLCSV-----LWDKGDCFYTLTDSSINKWDLD 290
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Mouse
Match: Nup133 (nucleoporin 133 [Source:MGI Symbol;Acc:MGI:2442620])

HSP 1 Score: 112.464 bits (280), Expect = 2.024e-24
Identity = 148/687 (21.54%), Postives = 286/687 (41.63%), Query Frame = 1 
Query: 1702 EIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVP----PMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKNSFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENIPPEHSFNIKQICQLQ---TRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESII---NLIINLVDFARNSDC-DEIFESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKY-IVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWK---------EITEDSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            ++ID++P  DPRW +++     +     N +LI+  QL  K +A    LLV   +    F  + + P    PMS    L               C+ +  L   + L         ++N  +       +  +  + C+       LT  ++  ++VS + T     CE L         +E+ E +  E +   ++  ++      +L + L+A+  YR    S + +    G         P W     P G+  +++    +I+ +V    +S   + + E ++ ++  +L+ +  +++ +E  S +Q     L   Y   R +L++ ++  G+       L++K+ DF  ++ +C+  DN ++      L+ Y+ ++ D  FS+F+  WY EK K   + ++                                  +  FL   E  +  WLHEI  +   +A  TL  L   +    + KKT L L+KL+ LAS  D+S +  +  I  + E   ++  QE +P  ++        +S+ P+L   QLI LY+     EN  + +Y   +AL+LL +  + + V          ++L + I     LQ ++W          E+++DS    V   ++   I+ GI + + LPE+ DL   E +  +  +   E+++K +YE
Sbjct:  566 DLIDDYPASDPRWAESVP---QEAPGLSNTSLIILHQLEDKMKA--HCLLVDFLHQVGLFRRLSSYPIRGTPMSTRLLL---------------CEHAEKLSAAITLKNHHSRLPDLVNSAI-------LLALNKRECE---VPNSLTPADVFFREVSQVDTI----CECL---------LEHEEQVLREVALVSQEWAEVAIDVNTVLKDMLQAATHYRLNKSSMYSQEEVLGK---EPEYVP-WTATSGPSGIRTAVMRQHGIILKMVYPQADSKLRNVVMEQLVALIDCFLDSYVSQLKSLEK-SSDQERYSSLEVEYLQKRSELLSPLLTLGQ-YPWAASLAEKYCDFDILVQMCEQTDNQAR------LQRYMTQFADQNFSDFLFRWYLEKGKRGKLLSQPISQHGQ---------------------------LANFLQAHE--HLSWLHEINSQELEKAHTTLLGLANMETRYFAKKKTLLGLSKLAALAS--DISEDRLQEKIEAMAEQERFLLHQETLPEQLLTE--RQLSLSAMPVLTAPQLISLYIC---DENRRANEYDFKKALDLLEYIDEEEDVS--------IDDLKLEILCRA-LQRDDWSGSDGKDDPIEVSKDS----VFVKILQKLIKDGIQLSEYLPEVTDLLRAEQLGSLKSNSYFEFVLKANYE 1148
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. UniProt/SwissProt
Match: sp|Q8R0G9|NU133_MOUSE (Nuclear pore complex protein Nup133 OS=Mus musculus OX=10090 GN=Nup133 PE=1 SV=2)

HSP 1 Score: 112.464 bits (280), Expect = 1.416e-23
Identity = 148/687 (21.54%), Postives = 286/687 (41.63%), Query Frame = 1 
Query: 1702 EIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVP----PMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKNSFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENIPPEHSFNIKQICQLQ---TRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESII---NLIINLVDFARNSDC-DEIFESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKY-IVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWK---------EITEDSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            ++ID++P  DPRW +++     +     N +LI+  QL  K +A    LLV   +    F  + + P    PMS    L               C+ +  L   + L         ++N  +       +  +  + C+       LT  ++  ++VS + T     CE L         +E+ E +  E +   ++  ++      +L + L+A+  YR    S + +    G         P W     P G+  +++    +I+ +V    +S   + + E ++ ++  +L+ +  +++ +E  S +Q     L   Y   R +L++ ++  G+       L++K+ DF  ++ +C+  DN ++      L+ Y+ ++ D  FS+F+  WY EK K   + ++                                  +  FL   E  +  WLHEI  +   +A  TL  L   +    + KKT L L+KL+ LAS  D+S +  +  I  + E   ++  QE +P  ++        +S+ P+L   QLI LY+     EN  + +Y   +AL+LL +  + + V          ++L + I     LQ ++W          E+++DS    V   ++   I+ GI + + LPE+ DL   E +  +  +   E+++K +YE
Sbjct:  566 DLIDDYPASDPRWAESVP---QEAPGLSNTSLIILHQLEDKMKA--HCLLVDFLHQVGLFRRLSSYPIRGTPMSTRLLL---------------CEHAEKLSAAITLKNHHSRLPDLVNSAI-------LLALNKRECE---VPNSLTPADVFFREVSQVDTI----CECL---------LEHEEQVLREVALVSQEWAEVAIDVNTVLKDMLQAATHYRLNKSSMYSQEEVLGK---EPEYVP-WTATSGPSGIRTAVMRQHGIILKMVYPQADSKLRNVVMEQLVALIDCFLDSYVSQLKSLEK-SSDQERYSSLEVEYLQKRSELLSPLLTLGQ-YPWAASLAEKYCDFDILVQMCEQTDNQAR------LQRYMTQFADQNFSDFLFRWYLEKGKRGKLLSQPISQHGQ---------------------------LANFLQAHE--HLSWLHEINSQELEKAHTTLLGLANMETRYFAKKKTLLGLSKLAALAS--DISEDRLQEKIEAMAEQERFLLHQETLPEQLLTE--RQLSLSAMPVLTAPQLISLYIC---DENRRANEYDFKKALDLLEYIDEEEDVS--------IDDLKLEILCRA-LQRDDWSGSDGKDDPIEVSKDS----VFVKILQKLIKDGIQLSEYLPEVTDLLRAEQLGSLKSNSYFEFVLKANYE 1148
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. UniProt/SwissProt
Match: sp|Q8WUM0|NU133_HUMAN (Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2)

HSP 1 Score: 110.153 bits (274), Expect = 6.383e-23
Identity = 156/692 (22.54%), Postives = 294/692 (42.49%), Query Frame = 1 
Query: 1684 VMEIIKEIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQ---IMTNTQCQEIETIFSKTCQKNSFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENI---PPEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESIIN---LIINLVDFARNSDCDEIF-ESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKY-IVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWK---------EITEDSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            V +I  +++D++P  DPRW +++    ++   + N +LI+  QL  K +A     L+   +    FG +G+ P     R   M    A RL +   C+ +  L   + L         ++N    I  N +  EI +              LT  ++  ++VS + T     CE L         +E+ E +    P  S    ++      IL + L+A+  YR+   S +       S        P W     P G+   II    +++ +     +S+   I  E ++ ++  +L+ +  +++ ++  S N+   ++L   Y   R DL++ ++  G+ +     L++K+ DF  ++ +C+  DN S+      L+ Y+ ++ D  FS+F+  WY EK K   + ++                                  +  FL   E  +  WLHEI  +   +A  TL  L   +    + KKT L L+KL+ LAS  D S +  +  I  + E   ++  QE +P  ++    +  ++S+ P+L   QLI LY+     EN  + +Y   +AL+LL +  + + +          N+L + I     LQ +NW          E+++DSI       ++   ++ GI + + LPE+ DL   + +  +  +   E+++K +YE
Sbjct:  561 VTQISVDLMDDYPASDPRWAESVP---EEAPGFSNTSLIILHQLEDKMKA--HSFLMDFIHQVGLFGRLGSFP----VRGTPM----ATRLLL---CEHAEKLSAAIVLKNHHSRLSDLVNTAILIALNKREYEIPS-------------NLTPADVFFREVSQVDTI----CECL---------LEHEEQVLRDAPMDSIEWAEVVINVNNILKDMLQAASHYRQNRNSLYRREE---SLEKEPEYVP-WTATSGPGGIRTVIIRQHEIVLKVAYPQADSNLRNIVTEQLVALIDCFLDGYVSQLKSVD-KSSNRERYDNLEMEYLQKRSDLLSPLLSLGQYL-WAASLAEKYCDFDILVQMCEQTDNQSR------LQRYMTQFADQNFSDFLFRWYLEKGKRGKLLSQPISQHGQ---------------------------LANFLQAHE--HLSWLHEINSQELEKAHATLLGLANMETRYFAKKKTLLGLSKLAALAS--DFSEDMLQEKIEEMAEQERFLLHQETLPEQLLAE--KQLNLSAMPVLTAPQLIGLYIC---EENRRANEYDFKKALDLLEYIDEEEDIN--------INDLKLEILCKA-LQRDNWSSSDGKDDPIEVSKDSI----FVKILQKLLKDGIQLSEYLPEVKDLLQADQLGSLKSNPYFEFVLKANYE 1149
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. UniProt/SwissProt
Match: sp|F1QNV4|NU133_DANRE (Nuclear pore complex protein Nup133 OS=Danio rerio OX=7955 GN=nup133 PE=2 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 1.788e-15
Identity = 100/437 (22.88%), Postives = 186/437 (42.56%), Query Frame = 1 
Query: 2437 IGVSESIINLIINLVDFARNSDCDEIFESVL--DVVAVYLNFFKHRIEWMES--HSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDIS--SQPILRVEQLIKLYLASAKSENDCSVKY-IVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITE---------DSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            +G   S+I+    L+  A     D    SVL   +VA+  +     +  + S      Q   + L   Y   R +L+  ++E G++ +    L++K+ DF  ++ LC+  DN S+      L+ Y+ K+ D  F++F+  WY EK K   + ++     +                            +  FL   +  +  WLH+I V+ + +A  TL      +    S KKT L+L+KL+ LAS  D+        +N I E   ++  QE +P    K +LE K ++  S P+L  + LI LY+     EN  + +Y   +AL+LL +  +   +     K +        I+S  +  + +WKE            ++   +    ++   I+  + +   LP++ DL   + ++ +      E+L++ +YE
Sbjct:  748 VGGVRSVISRQHELILRAAYPHADAELRSVLCEQLVALLDSLLSGYVAQLTSLRRGGQQERYDTLENEYTQKRSELLKPLLELGQH-QWVAALAEKYCDFDILVQLCERTDNQSR------LQQYMVKFADQNFADFLFRWYMEKGKRGKLLSQPMATHQQ---------------------------LASFLQAHD--HLSWLHDIHVQDYQRAHRTLYNQANMETRYFSKKKTLLALSKLTALAS--DMPEPVHRRQLNDIVEQERFLLHQETLP----KQLLEEKQLNPDSMPLLSPQNLISLYIC---DENRGANEYDFKKALDLLEYFEEENGIDVDALKRE--------IFSKAL--KKDWKESWSSSDDNDDPLEAARDSTFVKILQKLIQERVSLQTYLPDIKDLLQEDELESLKSKPYFEFLLRANYE 1129
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. UniProt/SwissProt
Match: sp|Q9VCW3|NU133_DROME (Nuclear pore complex protein Nup133 OS=Drosophila melanogaster OX=7227 GN=Nup133 PE=2 SV=2)

HSP 1 Score: 65.4698 bits (158), Expect = 3.777e-9
Identity = 86/383 (22.45%), Postives = 170/383 (44.39%), Query Frame = 1 
Query: 2617 LYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLS-LAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKYIVR-ALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITEDS----INSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYETLTADFKKSSPLPMEI 3747
            L + +   R +LI+ +++D +  E   K+++K++DF  ++ +CD   +      K  LE Y  KY +  FS+F +NW+  + +   +                 +R +                + +F+   +  +  W+  I    F +AA  L +L + +   ++ KK+ LS     +  A+E DL+     + +  I+  L  +++Q  +  +V++S     D + Q +L+ E++I LY+A    EN+ + +   R ALELLS+  Q   ++               IW   I + +NW +   ++    +   +   +I  +   G D   +LP M+D      + ++ Q    +YL+K +YE +   FK+  P  ME+
Sbjct:  880 LQQQFEAQRRELISVLIKD-RQYEYAAKIAEKYLDFQSLVLICDETQD------KERLEDYTRKYEEYDFSQFAINWHLRQNRHGEV----------------FERFKGNQT-----------ALAQFMR--DHPSLGWIQLIFNGDFERAAKVLYELAQCETEFVARKKSMLSLAKLAAFAAAESDLT-----AQVEKINADLTLVEYQSQLGHDVLESF--GFDPAEQKVLKAEEIISLYIA---EENETASETEFRKALELLSYVEQPYDMRH-------------KIWCAAI-KRDNWTDYDPNNAVHYMQKLLFYKIIEISQLMGNDSENVLPPMEDFLESVELGDLPQQKPFQYLLKLTYEYVADMFKQ--PDDMEL 1200
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. TrEMBL
Match: V4AAF7 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_233315 PE=4 SV=1)

HSP 1 Score: 145.976 bits (367), Expect = 2.078e-31
Identity = 161/694 (23.20%), Postives = 304/694 (43.80%), Query Frame = 1 
Query: 1702 EIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKNSFCKK----------LTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENIP-PEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSG---SYRSNSMTAPCWVTEPKPIGVSESI---INLIIN--LVDFARNSDCDEIFESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKY-IVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITE----DSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYETLTA 3711
            ++ID++P  DPRW + I        T  + +L++ QQL  K +A    L+  L+              + ++          DRL I           + +    E L     L Q+ T     E  T     C K+ F  +          LT  +I  ++VS I   I    E         ++ +  E  P P+    +  I  + + I+   L  +L YR+    A++     G    Y+        W +   P G+   +   +NL +   + +   +   + +F+ +L +  + L+ + +++E +     N+     L + Y+  R +LI  +VE+ +  ER L L++K+ DF  +I +C+  +N  +      L+ Y+ +Y + GFS  + +WY +  +   + ++    ++                            +G+FL+    +   WLH+I  + + QA  TL  L R + T  S KKT LSL+KL+ LAS+ + S + KE M + ID+ L  I  QE +PP+ ++ +    D ++  +L+ +++I+LY++     N  + +Y   +AL+LL +  Q          + + N L + IWS  +L++ NWK+       D+I  T+    ++ A   G+D+ + LP ++++   E + ++    N ++LIK  YE L +
Sbjct:  555 DVIDDYPASDPRWAQNIK---QGDVTNSSSSLLILQQLKDKEKA-HSYLIAFLKK-------------LHLW----------DRLSIINVNSTYMSTTSVLCEHAEKLTAAITLRQLQT-----EHHTDIIDECIKHVFKMRGENLRRLPSGLTPQDIFYREVSRIEEVIEALVE---------LETDTLEKEPSPQRRVTL--ITAVNS-IIEGMLTTALQYRQSKAEAYISPTILGLQQEYKP-------WTSTGGPRGLRTLLFKQVNLTVEGAVTEIKDDDTKNVVFQQLLVISDILLDGYSNQLESLRRSDGNEEAYITLEQKYQQERQNLITPLVEN-EEYERALSLAEKYSDFQTLIMVCEKTNNNER------LQRYVEQYNEQGFSTVLFDWYMKHGRRGRLFSQQIGNSRD---------------------------LGQFLESDNNRYLSWLHDISNQQYTQAHETLLDLARTETTFASKKKTLLSLSKLTALASD-NQSPDMKERM-DEIDDQLDLILHQEQLPPDSLQHL--GMDTNNMSVLKPQEIIELYISEI---NAVATEYEFKKALDLLQYLDQED-------DDIDINELRLHIWSKAVLRD-NWKDNKASDPLDTIKDTIFFKTVDLAYNEGLDLTEYLPSVEEILQSEELGDLRNHPNFQFLIKAGYEHLQS 1148
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. TrEMBL
Match: K1QYG2 (Uncharacterized protein OS=Crassostrea gigas OX=29159 GN=CGI_10017863 PE=4 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 5.540e-27
Identity = 103/404 (25.50%), Postives = 198/404 (49.01%), Query Frame = 1 
Query: 2506 DEIFESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKYIVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITEDSIN------STVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            ++I+  +  +  + L+ +  ++E ++  +  Q     L   Y   R  LI  ++E GK  E    L++K+ DF  +I LC+  DN  +      +E YL ++ D GF+ ++  WY ++ K   +        +                            +GKFL K +I+   WLH I+ ++F +A  TL +L R ++  LS KKT LSL+KL+ LA++ D    + +S I  I+E    I  Q+ +P  V++++    D  +  +L   QLI+LY++   +  D +     +AL+LL      +++ K + +  +  +L + IW+  IL+ ++W++  +DS++      +TV    ++ A + G+D+   +P +  + NCE + ++    + +YLI+  YE
Sbjct:  774 EKIYRQLASIADIILDGYVGQLESLKVKANRQQHYNELQRRYEQDRQQLIMPLME-GKQYELAASLAEKYYDFEILIQLCEVSDNTDR------IEKYLRQFSDKGFANYLYTWYMKEGKRGKLLALPISQQRE---------------------------LGKFLQKEDIKTLSWLHNIQTDNFSKAHLTLLELARMEQGSLSKKKTLLSLSKLAGLAADPD--NGDIDSNILDINEEQELIAHQQQLPALVIENLKMEPD--NMAVLSPVQLIELYISG--TNIDATEYDFKKALDLL------RYIDKTD-QTVDYESLRMHIWAQSILR-DSWQQ--DDSVDVMEAIMNTVFFKTVDLAYKEGVDVKTFMPGLKSILNCEELGDLKDSASFQYLIQAGYE 1127
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. TrEMBL
Match: A0A210Q825 (Nuclear pore complex protein Nup133 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT10019 PE=4 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 6.169e-26
Identity = 109/408 (26.72%), Postives = 190/408 (46.57%), Query Frame = 1 
Query: 2494 NSDCDEIF-ESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKS-ENDCSVKYIVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITE----DSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            ++D   +F + +  +  + L  F  ++E +    +       L   Y+  R  LI  ++E   ++E    L++K+ DF  +I LC+ +DN  +      +E YL ++ D GF++ +  WY ++ K   + +      +                            +G+FL   +I+   WLH+++   + QA  +L +L R + T LS KKT LSL+KL+ LAS+      E++  I GI+E L  I  QE +P +V+       D     +L  EQLI+LY++   S E + + K   +AL+LL +  +       N  N +   L   IW+  IL+ N+W         +++  TV   V   A + GID+ + LP ++ L  CE +  +  D N +YL++  YE
Sbjct:  775 DADTMSVFCQQLAQLADIVLEGFSTQLESLHHLQDRSGHYRELDRKYQLCRQQLITPLLEK-DHMELAASLAEKYYDFDILIQLCEQMDNSDR------IERYLTQFSDKGFADILYAWYMKEGKLGKLLSLPAHRHQE---------------------------LGQFLQSKDIKYLSWLHQLQTSDYSQAHESLLELSRMETTSLSKKKTLLSLSKLAGLASDDG----EEDVNITGINEELDLITHQEQLPAHVLHQ--RGLDPDEMEVLSPEQLIELYISDMSSEEQELNFK---KALDLLQYIDR-------NDPNIDVEALRYTIWAKAILR-NSWAVDQSGEPIETVKDTVFFKVATLAYDEGIDLREYLPGIELLLRCEDLGLLQDDRNFQYLLRVGYE 1131
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. TrEMBL
Match: A0A1S3F240 (nuclear pore complex protein Nup133 OS=Dipodomys ordii OX=10020 GN=Nup133 PE=4 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 4.539e-24
Identity = 158/689 (22.93%), Postives = 294/689 (42.67%), Query Frame = 1 
Query: 1684 VMEIIKEIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKNSFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENI---PPEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESII---NLIINLVDFARNSDCDEIF-ESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKY-IVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWK---------EITEDSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            V +I  +++D++P  DPRW +++    ++     N +LI+  QL  K +A    LLV   ++   F  +G  P     R   M    A RL +   C+ +  L   + L         ++N  +       +  +  + C+  S    LT  ++  ++VS + T     CE L         +E+ E +    P  S    ++      IL + L+A+  YR+   S + +    G         P W     P G+  +I+    +I+  V    +S+   I  E ++ ++  +L+ +  ++  ++  S NQ    +L   Y   R DL++ ++  G++      L++K+ DF  ++ +C+  DN ++      L+ Y+ ++ D  FS+F+  WY EK K   + ++                                  +  FL   E  +  WLHEI  +   +A  TL  L   +    + KKT L L+KL+ LAS  DLS +  +  I  + E   ++  QE +P  ++    +   +S+ P+L   QLI LY+     EN  + +Y   +AL+LL +  + + V          N+L + I     LQ +NW          E+++DS    V   ++   ++ GI + + LPE+ DL   + +  +  +   E+++K +YE
Sbjct:  116 VTQISVDLVDDYPASDPRWAESVP---EEAPGLSNTSLIILHQLEDKVKA--HCLLVDFLHHVGLFERLGTSP----VRGTLM----ATRLLL---CEHAEKLSAAIALKNHHSRLPDLVNTAI-------LMALNKRDCEVPS---SLTPADVFFREVSQVDT----VCECL---------LEHEEQVLRDAPLDSVEWAEVAISVNTILKDMLQAATHYRQNRSSMYRQEEPVGK---EPEYVP-WTATSGPAGIRTAIVRQHGVILKTVYPQADSNLRNIVTEQLVALIDCFLDGYVLQLRSLDKPS-NQERYTNLEVEYLQKRSDLLSLLLTSGQHA-WAASLAEKYCDFDILVQMCEQTDNQAR------LQRYMTQFADQNFSDFLFRWYLEKGKRGKLLSQPISQHGQ---------------------------LANFLQAHE--HLSWLHEINSQELEKAHATLLGLANMETRYFAKKKTLLGLSKLAALAS--DLSEDTLQEKIEAMAEQERFLLHQETLPEQLLSE--KQLSLSAMPVLTAPQLISLYIC---EENRRANEYDFKKALDLLEYIDEEEDVN--------INDLKLEILCRA-LQRDNWSSSDGKDDPIEVSKDS----VFVKILQKLLKDGIQLNEYLPEVKDLLQADQLGSLKSNPYFEFILKANYE 704
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. TrEMBL
Match: A0A0K2TIA8 (Nucleoporin_C domain-containing protein OS=Lepeophtheirus salmonis OX=72036 PE=4 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 1.577e-23
Identity = 153/712 (21.49%), Postives = 313/712 (43.96%), Query Frame = 1 
Query: 1633 SQIEESQINPEISIPLFVMEIIKEIIDEHPTKDPRWVKTISLPSDQQF--TWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNV-----PPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKNSFCKK---LTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENIPPEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESIINL----IINLVDFARNS-DCDEIFESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKYI--VRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITE----DSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYETL 3705
             Q++E +IN   S    ++++ +++ID++P  DPRW++++  PS+Q+      + ++++  QL  K+ A+   L V        +  M  V     PPMS +  L      A+ L+          ++  + L     EF  V            IE       +  S+ KK   LT  +   ++VS +   ++   E +              +I  +    I  I     R++ + ++ ++ YR      F+         +  +    W + P P G+   ++N     +  +V  ++ S D    ++ +++   + L+ +  +IE + S S ++   E + + Y   R  LI  ++ + +  E    L++K+ +F  ++ LC+  ++      K  LE Y+ ++    FS+FV +W+ ++ K+  +          Q      +R E+               +G+FL         W+H+++   F  A+ TL KL   +  +L+ KKT LSL+KL+ LAS+++   E  +  I  I++ L     QE +P  V+++     D  S  +L  +++I+LY+    S+ + +  +I   +AL+L+ + R        + ++KEA  L + IW+  IL+ NNW+ +      DS+  T    +       G+++   L   ++L     ++ I+ + N ++ ++ +YE L
Sbjct:  170 GQVQEGEINS--STNKVIVQVSRDVIDDYPAMDPRWMESLP-PSEQKIERVGASMSMLIKHQLEDKKTALD--LYVNFIKKVGLWKRMSGVVVDDSPPMSTHLAL------AEHLE---------KIVAALALRNMKAEFSEV------------IEKAIKIVLKDRSYYKKTGNLTPQDHFYREVSKVEQIVSGLLEVVK------------HSIATDQPDKITSIVSSCNRVVLSIIKEAVNYRSNKLDEFLPLG-----NAKDLEYLPWTSSPGPSGLRSCLMNFYKYTLEQVVPLSKGSIDRSGFYQQLVEFADIILDGYNTQIESICSKSISERR-EEVGKQYEKDRLSLIMPLITN-EYYEEAASLAEKYFEFGGLVKLCEITND------KERLERYMDRFAAQKFSDFVFDWHVKEGKQGRL--------LSQVQKSGNRRQEE---------------LGRFLSGH--AGFSWVHDVQTNKFKDASLTLKKLALNEIEILARKKTMLSLSKLTALASDEN--EEVVKPFIEDIEQELTTSLAQEQLPLAVLEAFNLSPD--SMNVLSPKEIIELYI----SDENFNADHIDFKKALDLMDYIRDM------DIEDKEA--LKLHIWARSILR-NNWENMDAANPVDSVKETTFFKLAEFCQLQGLELQCQLLSYENLLGASELQSISNNKNFQFFLQTAYEHL 782
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Cavefish
Match: nup133 (nucleoporin 133 [Source:NCBI gene;Acc:103026587])

HSP 1 Score: 94.7449 bits (234), Expect = 4.306e-19
Identity = 113/491 (23.01%), Postives = 207/491 (42.16%), Query Frame = 1 
Query: 2302 ILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAP-----CWVTEPKPIGVS-------ESIINLIINLVDFARNSDCDEIFESVLD-VVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYK--DISSQPILRVEQLIKLYLASAKSENDCSVKY-IVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKE------ITEDSINS---TVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            I+ + L+A+  YR+   S          YR+   TAP      W       GV        E I+ L+    D +  S  +E   ++LD ++  Y+          +    N  E+E     Y   R +L+  ++E G+  +    L++KF DF  ++ +C+  DN ++      L++Y+ K+ +  F++F+  WY EK K   + ++     +                            +  FL     Q+  WLH I  + F  A +TL+     +    S KKT L+L+KL+ LAS  D+    +   ++ I E   ++  QE +P    K +LE K  +  + P+L    LI LY+     +N  + +Y   +AL+LL +  +   V     K +        I+S  +  + +WKE       T+D + +   ++   ++   I+ G+ +   LP++ DL   E +  +      E+L++ +YE
Sbjct:  710 IIKDMLQAAAQYRETKSSL---------YRAAENTAPEPEYIPWTASGGVGGVRTVIVRQHEVILRLVYPHADSSLRSTLNEQLVALLDSLLGGYVAQLTSLRRPGQQERYNALEME-----YTQRRSELLTPLLELGQ-YQWVAALAEKFCDFDILVQMCEQTDNQNR------LQHYMAKFAEQDFADFLFRWYMEKGKRGKLLSQPIAQHQQ---------------------------LSSFLQAH--QHLSWLHHIHTQDFQNAHHTLNSQANTETRYFSKKKTLLALSKLTALAS--DMPEALQHKQVDDIVEQERFLLHQETLP----KQLLEEKQQNPDTMPLLSAHNLINLYIC---DDNRGANEYDFKKALDLLEYIDEEDAVDIEALKRE--------IFSKAL--KKDWKENWSASDSTDDPLEAAKESIFVKILQKLIQEGVPLQSYLPDVKDLLQVEEMDSLKSRPFFEFLLRANYE 1131
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Sea Lamprey
Match: nup133 (nucleoporin 133 [Source:NCBI gene;Acc:406852])

HSP 1 Score: 87.8113 bits (216), Expect = 1.272e-17
Identity = 85/347 (24.50%), Postives = 163/347 (46.97%), Query Frame = 1 
Query: 2677 KNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSE-NDCSVKYIVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEI--TEDSI---NSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYE 3699
            +  ER   L++K+ DF  ++ LC+  +N ++      L+ Y+ ++ D  FSEFV  WY EK K + +  +                                 +IG        Q+  W H + + SF QA+ TL  L   +      KKT LSL+KLS  A   D+S ++  ++IN ID    ++ +Q+ +P  ++++  +  D+ S  +L   +LI +Y++    E N+   K   +AL+LL +  +       +  + +   L + I+  ++L+ N+W  +  T+D +   N +V A ++   ++ G+D+  ++P  + L  C  +  +  D   E+L++ +YE
Sbjct:  830 RQYERAAALAEKYSDFDVLVRLCEETNNQAR------LQRYMTQFADKNFSEFVFRWYMEKGKRSKLLTQPAAQHSQLNT----------------------FLIGH-------QHLSWPHHVHMASFTQASQTLRSLAEQEACYFMRKKTLLSLSKLS--ALASDMSPQDTHTLINNIDAEQDFMMYQDSLPLKLLEA--KEMDVDSMRVLSANELIMMYISDDNREANEFDFK---KALDLLQYIEE-------DCVDVDIEELKVKIFCQMLLR-NDWAAMLRTDDPVRAANDSVFARLMELLLQDGLDLRLVMPAPEALLGCSSLGVLRSDPAFEFLLRANYE 1126
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Medaka
Match: nup133 (nucleoporin 133 [Source:NCBI gene;Acc:101160289])

HSP 1 Score: 80.8777 bits (198), Expect = 7.861e-15
Identity = 136/597 (22.78%), Postives = 254/597 (42.55%), Query Frame = 1 
Query: 1684 VMEIIKEIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKN--SFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENIPPEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTA--PCWV--TEPKPIGVSESIINLIINLVDFA---------RNSDCDEIFESVLDV-----VAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASA-KSENDCSVKYIVRALELLSF 3411
            V +I  E++D++P  DPRW +++    D+   +   +LI+  QL  K +A    +  LL+      G +  +  ++V          A RL +   C+ +  L+  + L     +   ++N+ +            S   Q++  S    LT  ++  ++VS I + + +C   L  +   L   EY     P  S    ++  +   I+ + L+A+  YR         N  +  YR+    A  P ++  T    IG   S+I+   N+V  +         R+S C+++  ++LD+     VA   +  + R    +    N  E+E     Y   R +L++ ++E G+  +    L++K+ DF  ++ +C+  DN ++      L++Y+ K+ D  FS+FV  WY EK K   + ++     +                            +  FL     Q+  WLH + V  +  A  TL     A+      KKT L+L+KL+ LAS  DL  ++    ++ I E   ++  QE +P  +++   +  D  + P+L    LI+LY+    +  N+   K   +AL+LL +
Sbjct:  539 VTQINLELVDDYPASDPRWAESVP---DESAGFPLMSLIIVHQLEDKMKAHGCFMDFLLQ-----VGLLDRLTQVTVRSSPM-----ATRLLL---CEHAEKLMAAMVLKNHHTKHGELVNRAI------------SAALQRSGTSIPPSLTPADVFFREVSQISS-VFDC--LLEEEERSL--KEY-----PVDSVQWAEVVLIVNSIIKDMLQAACQYR---------NTKASMYRAPERAAVEPEYIPWTASGGIGGVRSVISRQHNIVLSSVYPHADSQLRSSLCEQLV-ALLDIYLSSYVAQLTSLQQPRPAGAQQERYNSLEME-----YSQRRSELLSPLLELGQ-YQWVAALAEKYCDFDILVQMCEQTDNQNR------LQHYMAKFADQNFSDFVFRWYMEKGKRGKLLSQPAAQHQQ---------------------------LASFLKSH--QHLSWLHNVHVHDYQSAFRTLYSQATAETRYFVKKKTLLALSKLTALAS--DLPDDQINKQVDEIVEQERFLLHQETLPRQLLEEKQQNPD--TMPLLNAHSLIQLYICDDNRRANEYDFK---KALDLLQY 1039
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Medaka
Match: nup133 (nucleoporin 133 [Source:NCBI gene;Acc:101160289])

HSP 1 Score: 67.0106 bits (162), Expect = 1.135e-10
Identity = 135/597 (22.61%), Postives = 251/597 (42.04%), Query Frame = 1 
Query: 1684 VMEIIKEIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKN--SFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENIPPEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTA--PCWV--TEPKPIGVSESIINLIINLVDFA---------RNSDCDEIFESVLDV-----VAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASA-KSENDCSVKYIVRALELLSF 3411
            V +I  E++D++P  DPRW +++    D+   +   +LI+  QL  K +A    +  LL+      G +  +  ++V          A RL +   C+ +  L+  + L     +   ++N+ +            S   Q++  S    LT  ++  ++VS I + + +C   L  +   L   EY     P  S    ++  +   I+ + L+A+  YR         N  +  YR+    A  P ++  T    IG   S+I+   N+V  +         R+S C+++  ++LD+     VA   +  + R    +    N  E+E     Y   R +L++ ++E G+  +    L++K+ DF  ++ +C+  DN ++      L++Y+ K+ D  FS+FV  WY EK K   + ++     +                            +  FL     Q+  WLH +       A  TL     A+      KKT L+L+KL+ LAS  DL  ++    I   + +L +   QE +P  +++   +  D  + P+L    LI+LY+    +  N+   K   +AL+LL +
Sbjct:  441 VTQINLELVDDYPASDPRWAESVP---DESAGFPLMSLIIVHQLEDKMKAHGCFMDFLLQ-----VGLLDRLTQVTVRSSPM-----ATRLLL---CEHAEKLMAAMVLKNHHTKHGELVNRAI------------SAALQRSGTSIPPSLTPADVFFREVSQISS-VFDCL--LEEEERSL--KEY-----PVDSVQWAEVVLIVNSIIKDMLQAACQYR---------NTKASMYRAPERAAVEPEYIPWTASGGIGGVRSVISRQHNIVLSSVYPHADSQLRSSLCEQLV-ALLDIYLSSYVAQLTSLQQPRPAGAQQERYNSLEME-----YSQRRSELLSPLLELGQ-YQWVAALAEKYCDFDILVQMCEQTDNQNR------LQHYMAKFADQNFSDFVFRWYMEKGKRGKLLSQPAAQHQQ---------------------------LASFLKSH--QHLSWLHNV------HAFRTLYSQATAETRYFVKKKTLLALSKLTALAS--DLPDDQINKQIVEQERFLLH---QETLPRQLLEEKQQNPD--TMPLLNAHSLIQLYICDDNRRANEYDFK---KALDLLQY 932
[Close]
BLAST of Nuclear pore complex protein Nup133 vs. Planmine SMEST
Match: SMESG000034820.1 (SMESG000034820.1)

HSP 1 Score: 2436.76 bits (6314), Expect = 0.000e+0
Identity = 1215/1215 (100.00%), Postives = 1215/1215 (100.00%), Query Frame = 1 
Query:  109 MFKVHSFGQGLHNKITESLKNCGDQSKIRLINDHMLVINRNSMLIWKYIFFQKNTISACKEYFLPNSEIEYSANQGMIIYDQTNKKSCIVVGDDAIVRFWPDIGYPNEYIDQRIPNIYNDSCILIERVYDNVLIFVFKSMKFIIADLKDFADAGISFKQFSQPTGFINGIRSCLSSFFVTNANQESSFINIKISTNLSEETTEMFILFDNNIDCLSLDVLHNSRYTKAILNQITIKKAICEQYKNIFAMQLENWNLIIKNFDILRNVFYMLLEINQFGSHTKKYMMVTYNRNLDIIDSVAEIERKFTGNIDIKVIDDELQSLSQPCLITLVKDNNSLSIIEVLTGDIKAKFVANNSIIGWANPKLQEDNHIIAAILTSCNQLVYIRQKINPFHADISKLQTEANFSDISFQDITPRKINVQGDMDMSDISYSSKTRYQTVQLSSRSQLDQMGDRILEDGNLAVINPFANLKANSSYCLTVENTPFAEFRKSIMLHWLGYQTHANRLIISQIEESQINPEISIPLFVMEIIKEIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKNSFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENIPPEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESIINLIINLVDFARNSDCDEIFESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNXXXXXXXXXXXXXXXXRIEDGXXXXXXXXXXXXLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKYIVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITEDSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYETLTADFKKSSPLPMEIVA 3753
            MFKVHSFGQGLHNKITESLKNCGDQSKIRLINDHMLVINRNSMLIWKYIFFQKNTISACKEYFLPNSEIEYSANQGMIIYDQTNKKSCIVVGDDAIVRFWPDIGYPNEYIDQRIPNIYNDSCILIERVYDNVLIFVFKSMKFIIADLKDFADAGISFKQFSQPTGFINGIRSCLSSFFVTNANQESSFINIKISTNLSEETTEMFILFDNNIDCLSLDVLHNSRYTKAILNQITIKKAICEQYKNIFAMQLENWNLIIKNFDILRNVFYMLLEINQFGSHTKKYMMVTYNRNLDIIDSVAEIERKFTGNIDIKVIDDELQSLSQPCLITLVKDNNSLSIIEVLTGDIKAKFVANNSIIGWANPKLQEDNHIIAAILTSCNQLVYIRQKINPFHADISKLQTEANFSDISFQDITPRKINVQGDMDMSDISYSSKTRYQTVQLSSRSQLDQMGDRILEDGNLAVINPFANLKANSSYCLTVENTPFAEFRKSIMLHWLGYQTHANRLIISQIEESQINPEISIPLFVMEIIKEIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKNSFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENIPPEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESIINLIINLVDFARNSDCDEIFESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNKGKLLAKIQKILQKIQRIEDGNISSRMNNSNSSLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKYIVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITEDSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYETLTADFKKSSPLPMEIVA
Sbjct:    1 MFKVHSFGQGLHNKITESLKNCGDQSKIRLINDHMLVINRNSMLIWKYIFFQKNTISACKEYFLPNSEIEYSANQGMIIYDQTNKKSCIVVGDDAIVRFWPDIGYPNEYIDQRIPNIYNDSCILIERVYDNVLIFVFKSMKFIIADLKDFADAGISFKQFSQPTGFINGIRSCLSSFFVTNANQESSFINIKISTNLSEETTEMFILFDNNIDCLSLDVLHNSRYTKAILNQITIKKAICEQYKNIFAMQLENWNLIIKNFDILRNVFYMLLEINQFGSHTKKYMMVTYNRNLDIIDSVAEIERKFTGNIDIKVIDDELQSLSQPCLITLVKDNNSLSIIEVLTGDIKAKFVANNSIIGWANPKLQEDNHIIAAILTSCNQLVYIRQKINPFHADISKLQTEANFSDISFQDITPRKINVQGDMDMSDISYSSKTRYQTVQLSSRSQLDQMGDRILEDGNLAVINPFANLKANSSYCLTVENTPFAEFRKSIMLHWLGYQTHANRLIISQIEESQINPEISIPLFVMEIIKEIIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLVLLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCVGLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKNSFCKKLTSLEIITQKVSLIPTFINECCEYLNAKRDGLIDMEYFENIPPEHSFNIKQICQLQTRILTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSESIINLIINLVDFARNSDCDEIFESVLDVVAVYLNFFKHRIEWMESHSENQTELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDALDNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNKGKLLAKIQKILQKIQRIEDGNISSRMNNSNSSLVIGKFLDKAEIQNTRWLHEIEVESFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMINGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAKSENDCSVKYIVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQENNWKEITEDSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEITQDLNIEYLIKKSYETLTADFKKSSPLPMEIVA 1215
The following BLAST results are available for this feature:
BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
NUP1331.329e-2322.54nucleoporin 133 [Source:HGNC Symbol;Acc:HGNC:18016... [more]
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Nup1331.548e-1121.41gene:FBgn0039004 transcript:FBtr0084302[more]
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nup1332.369e-1622.88nucleoporin 133 [Source:NCBI gene;Acc:406852][more]
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
NUP1335.608e-1525.80nucleoporin 133kDa [Source:NCBI gene;Acc:100494693... [more]
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Nup1332.024e-2421.54nucleoporin 133 [Source:MGI Symbol;Acc:MGI:2442620... [more]
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BLAST of Nuclear pore complex protein Nup133 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q8R0G9|NU133_MOUSE1.416e-2321.54Nuclear pore complex protein Nup133 OS=Mus musculu... [more]
sp|Q8WUM0|NU133_HUMAN6.383e-2322.54Nuclear pore complex protein Nup133 OS=Homo sapien... [more]
sp|F1QNV4|NU133_DANRE1.788e-1522.88Nuclear pore complex protein Nup133 OS=Danio rerio... [more]
sp|Q9VCW3|NU133_DROME3.777e-922.45Nuclear pore complex protein Nup133 OS=Drosophila ... [more]
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BLAST of Nuclear pore complex protein Nup133 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
V4AAF72.078e-3123.20Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
K1QYG25.540e-2725.50Uncharacterized protein OS=Crassostrea gigas OX=29... [more]
A0A210Q8256.169e-2626.72Nuclear pore complex protein Nup133 OS=Mizuhopecte... [more]
A0A1S3F2404.539e-2422.93nuclear pore complex protein Nup133 OS=Dipodomys o... [more]
A0A0K2TIA81.577e-2321.49Nucleoporin_C domain-containing protein OS=Lepeoph... [more]
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nup1334.306e-1923.01nucleoporin 133 [Source:NCBI gene;Acc:103026587][more]
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nup1331.272e-1724.50nucleoporin 133 [Source:NCBI gene;Acc:406852][more]
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nuclear pore complex protein Nup133 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nup1337.861e-1522.78nucleoporin 133 [Source:NCBI gene;Acc:101160289][more]
nup1331.135e-1022.61nucleoporin 133 [Source:NCBI gene;Acc:101160289][more]
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BLAST of Nuclear pore complex protein Nup133 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000034820.10.000e+0100.00SMESG000034820.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006342 ID=SMED30006342|Name=Nuclear pore complex protein Nup133|organism=Schmidtea mediterranea sexual|type=transcript|length=3791bp
GTAAATTCGGTTGTTTAAATATTAAAATAATTGAATTTAAATATAGTTAT
AAAGATGAGCCTATCTAGAATTTCCAACTCATATATCTTTAAAGATTTCA
ATAATGGAATGTTTAAAGTTCATAGCTTTGGACAAGGGCTACATAATAAA
ATTACTGAATCGTTAAAGAACTGTGGCGATCAATCAAAAATTCGTTTAAT
TAATGATCACATGTTAGTTATAAATAGAAATTCAATGCTTATTTGGAAAT
ATATATTTTTTCAAAAGAATACAATTTCGGCTTGTAAAGAATATTTCTTA
CCAAACAGTGAGATAGAATACAGTGCAAATCAAGGAATGATTATTTATGA
TCAAACAAATAAAAAATCTTGTATTGTTGTTGGAGATGATGCCATTGTCA
GGTTTTGGCCTGATATTGGATATCCAAATGAATATATCGACCAAAGAATT
CCAAATATATACAACGATTCATGCATATTAATTGAACGAGTCTACGATAA
TGTTCTTATTTTCGTTTTCAAAAGCATGAAATTTATTATTGCTGACTTGA
AAGACTTTGCTGACGCAGGAATAAGTTTTAAACAGTTTTCCCAACCGACT
GGTTTCATTAACGGAATCAGAAGTTGTTTGAGCTCGTTTTTCGTCACCAA
TGCCAACCAGGAATCCTCATTCATTAATATCAAAATAAGCACAAATTTGA
GCGAAGAAACTACAGAAATGTTCATTCTATTTGACAATAATATTGATTGC
TTGAGTTTAGATGTGTTACACAATAGCAGGTACACTAAAGCCATTCTAAA
CCAAATTACCATCAAAAAAGCGATTTGTGAGCAATATAAAAATATATTCG
CAATGCAGTTAGAAAACTGGAATTTGATAATAAAAAATTTTGATATTCTC
CGAAACGTCTTCTATATGTTACTGGAAATCAACCAGTTCGGTAGTCATAC
GAAAAAGTATATGATGGTTACGTACAACAGAAATCTCGACATTATTGATT
CTGTGGCAGAAATTGAAAGAAAGTTTACAGGAAACATAGATATCAAAGTT
ATAGATGACGAATTGCAGAGTTTAAGTCAACCATGTTTGATAACATTAGT
GAAAGACAATAACTCATTATCTATTATCGAAGTTTTAACTGGGGACATCA
AGGCAAAATTTGTTGCTAATAATTCCATTATTGGGTGGGCAAATCCTAAA
TTGCAGGAAGATAATCACATAATTGCTGCAATCTTAACTTCTTGCAATCA
ATTGGTTTACATCAGACAGAAAATCAACCCGTTTCACGCCGATATTAGTA
AATTACAGACCGAGGCAAATTTTTCTGATATCAGCTTCCAAGACATTACA
CCGAGGAAAATAAATGTTCAAGGGGATATGGATATGAGTGATATTAGCTA
TTCGTCTAAAACTCGCTACCAGACAGTACAATTATCATCTAGATCTCAAC
TAGATCAAATGGGAGATAGAATACTAGAAGATGGCAATTTAGCTGTTATT
AATCCGTTTGCAAATCTAAAAGCAAATAGTTCTTATTGCTTAACTGTTGA
AAATACGCCATTTGCTGAATTCCGAAAATCTATAATGCTTCATTGGCTTG
GTTATCAAACCCATGCAAACAGACTTATAATCTCTCAAATTGAAGAATCT
CAAATTAATCCTGAAATATCTATTCCACTATTTGTTATGGAAATTATCAA
AGAAATTATCGATGAACACCCAACAAAAGACCCTAGATGGGTTAAAACCA
TTTCCCTACCATCTGACCAACAGTTCACCTGGTGTAATAAGACGTTGATT
TTAACACAACAACTGGCATCGAAACGAGAAGCTATTCAAAAAGTTTTATT
GGTTTTACTGGAAAATAATTTCGATTTTTTCGGTTCGATGGGAAATGTTC
CACCGATGTCGGTGTATAGATGTTTATTTATGCAGGATGATGAAGCAGAT
AGGTTACAGATCTATGGGGACTGTAAGGTAAGTTGGCCATTGATCAATTG
TGTTGGCCTGGCTGGAGAAATGCTAGAATTCGTTAGTGTCCTCAATCAAA
TCATGACTAATACTCAGTGCCAGGAAATCGAAACCATATTTAGCAAAACC
TGTCAAAAAAACTCGTTTTGTAAAAAGTTAACGTCTTTGGAAATAATAAC
TCAAAAAGTTTCATTAATACCGACGTTCATAAATGAATGTTGTGAATATT
TGAATGCCAAACGTGACGGACTTATCGACATGGAATATTTTGAGAATATT
CCACCGGAACACAGCTTTAATATAAAACAAATTTGTCAACTTCAGACTCG
AATATTGACCAACTGTCTTCGTGCTTCATTGTTGTATAGGAAAAAATTTG
AATCTGCATTTGTAGAAAATAATTTCAGTGGTTCGTATAGATCTAATTCT
ATGACTGCTCCTTGCTGGGTTACTGAACCGAAACCGATTGGGGTTTCAGA
ATCTATTATTAATCTAATAATAAATCTTGTCGATTTTGCTCGAAATAGTG
ATTGTGATGAAATATTCGAATCTGTGTTAGATGTTGTGGCAGTGTACCTC
AATTTCTTCAAGCATCGCATTGAATGGATGGAGTCACATAGCGAAAATCA
AACTGAATTGGAACATCTTTATGAAATGTATCGAGATATACGGTTTGATC
TGATAAATAAAATAGTGGAAGATGGGAAAAATATCGAAAGAGGATTAAAG
CTATCGGATAAATTTATGGATTTCCATTGGATTATTACTCTATGTGATGC
ACTTGATAATTTATCTAAAGACGGTAGCAAAATGCATTTAGAATATTATC
TACACAAATATTGTGATGATGGATTTTCTGAATTCGTTTTGAACTGGTAT
CAAGAGAAATTAAAAGAGAATAATATTCCAAATAAAGGAAAATTATTAGC
TAAAATCCAAAAGATATTACAGAAAATTCAAAGAATAGAAGATGGGAATA
TTAGTAGTAGAATGAATAACAGCAATAGTTCTTTGGTAATTGGGAAATTT
CTTGATAAAGCCGAAATTCAAAACACAAGGTGGCTTCATGAGATAGAAGT
GGAAAGTTTTGGACAGGCAGCAAATACATTGGATAAATTATGGCGAGCAA
AGGAGACATTACTCTCTCACAAAAAGACATATCTTAGCCTCGCCAAACTG
AGCTGCCTAGCTTCAGAACAAGATTTAAGTAGAGAGGAGAAAGAGTCAAT
GATAAACGGAATTGATGAATATTTGCATTACATTCAATTTCAAGAAGATA
TCCCCCCGAATGTTGTAAAATCGATGCTAGAATATAAAGACATTTCCTCT
CAACCGATACTTCGAGTTGAACAGCTTATTAAATTATATTTAGCCAGTGC
AAAATCGGAAAATGATTGCTCTGTGAAATATATTGTCCGTGCGTTGGAGT
TACTGAGTTTCGCTCGGCAGGCTAAACACGTGAAAAAAGGCAATTTTAAG
AATAAAGAAGCTAATAATCTTGCTATTGCAATTTGGAGCCATGTTATACT
TCAGGAAAATAACTGGAAAGAAATAACCGAGGACTCAATCAATTCTACCG
TCATGGCAACCGTTATAAATGCTGCTATTGAATCTGGAATCGATATCGGA
CAGTTATTACCGGAAATGGACGATTTGTGCAATTGTGAACCGGTGAAAGA
GATTACACAAGATCTAAACATAGAATACCTGATCAAGAAATCATATGAAA
CATTGACTGCAGATTTCAAGAAGAGTTCTCCTCTCCCAATGGAAATTGTC
GCTTAAGTGCGAATATTGATTTGTAGATATAAATAAATGAT
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protein sequence of SMED30006342-orf-1

>SMED30006342-orf-1 ID=SMED30006342-orf-1|Name=SMED30006342-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1234bp
MSLSRISNSYIFKDFNNGMFKVHSFGQGLHNKITESLKNCGDQSKIRLIN
DHMLVINRNSMLIWKYIFFQKNTISACKEYFLPNSEIEYSANQGMIIYDQ
TNKKSCIVVGDDAIVRFWPDIGYPNEYIDQRIPNIYNDSCILIERVYDNV
LIFVFKSMKFIIADLKDFADAGISFKQFSQPTGFINGIRSCLSSFFVTNA
NQESSFINIKISTNLSEETTEMFILFDNNIDCLSLDVLHNSRYTKAILNQ
ITIKKAICEQYKNIFAMQLENWNLIIKNFDILRNVFYMLLEINQFGSHTK
KYMMVTYNRNLDIIDSVAEIERKFTGNIDIKVIDDELQSLSQPCLITLVK
DNNSLSIIEVLTGDIKAKFVANNSIIGWANPKLQEDNHIIAAILTSCNQL
VYIRQKINPFHADISKLQTEANFSDISFQDITPRKINVQGDMDMSDISYS
SKTRYQTVQLSSRSQLDQMGDRILEDGNLAVINPFANLKANSSYCLTVEN
TPFAEFRKSIMLHWLGYQTHANRLIISQIEESQINPEISIPLFVMEIIKE
IIDEHPTKDPRWVKTISLPSDQQFTWCNKTLILTQQLASKREAIQKVLLV
LLENNFDFFGSMGNVPPMSVYRCLFMQDDEADRLQIYGDCKVSWPLINCV
GLAGEMLEFVSVLNQIMTNTQCQEIETIFSKTCQKNSFCKKLTSLEIITQ
KVSLIPTFINECCEYLNAKRDGLIDMEYFENIPPEHSFNIKQICQLQTRI
LTNCLRASLLYRKKFESAFVENNFSGSYRSNSMTAPCWVTEPKPIGVSES
IINLIINLVDFARNSDCDEIFESVLDVVAVYLNFFKHRIEWMESHSENQT
ELEHLYEMYRDIRFDLINKIVEDGKNIERGLKLSDKFMDFHWIITLCDAL
DNLSKDGSKMHLEYYLHKYCDDGFSEFVLNWYQEKLKENNIPNKGKLLAK
IQKILQKIQRIEDGNISSRMNNSNSSLVIGKFLDKAEIQNTRWLHEIEVE
SFGQAANTLDKLWRAKETLLSHKKTYLSLAKLSCLASEQDLSREEKESMI
NGIDEYLHYIQFQEDIPPNVVKSMLEYKDISSQPILRVEQLIKLYLASAK
SENDCSVKYIVRALELLSFARQAKHVKKGNFKNKEANNLAIAIWSHVILQ
ENNWKEITEDSINSTVMATVINAAIESGIDIGQLLPEMDDLCNCEPVKEI
TQDLNIEYLIKKSYETLTADFKKSSPLPMEIVA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006913nucleocytoplasmic transport
GO:0000972transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0006325chromatin organization
GO:0006355regulation of transcription, DNA-templated
GO:0006406mRNA export from nucleus
GO:0006409tRNA export from nucleus
GO:0006606protein import into nucleus
GO:0006810transport
GO:0006999nuclear pore organization
GO:0007062sister chromatid cohesion
GO:0007077mitotic nuclear envelope disassembly
GO:0010827regulation of glucose transport
GO:0015031protein transport
GO:0016032viral process
GO:0016925protein sumoylation
GO:0019083viral transcription
GO:0021915neural tube development
GO:0022008neurogenesis
GO:0031047gene silencing by RNA
GO:0031081nuclear pore distribution
GO:0048339paraxial mesoderm development
GO:0051028mRNA transport
GO:0061053somite development
GO:0075733intracellular transport of virus
GO:1900034regulation of cellular response to heat
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR037624Nup133-like
IPR015943WD40/YVTN_repeat-like_dom_sf
IPR007187Nucleoporin_Nup133/Nup155_C
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0005487nucleocytoplasmic transporter activity
GO:0017056structural constituent of nuclear pore
Vocabulary: cellular component
TermDefinition
GO:0000775chromosome, centromeric region
GO:0000776kinetochore
GO:0000777condensed chromosome kinetochore
GO:0005634nucleus
GO:0005635nuclear envelope
GO:0005643nuclear pore
GO:0005694chromosome
GO:0005829cytosol
GO:0016020membrane
GO:0031080nuclear pore outer ring
GO:0031965nuclear membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007187Nucleoporin, Nup133/Nup155-like, C-terminalPFAMPF03177Nucleoporin_Ccoord: 816..1083
e-value: 3.2E-12
score: 46.0
NoneNo IPR availableGENE3DG3DSA:1.25.40.700coord: 502..1220
e-value: 5.5E-63
score: 215.6
NoneNo IPR availableSUPERFAMILYSSF117289Nucleoporin domaincoord: 52..262
IPR015943WD40/YVTN repeat-like-containing domain superfamilyGENE3DG3DSA:2.130.10.10coord: 11..347
e-value: 8.5E-23
score: 82.9
IPR037624Nuclear pore complex protein Nup133-likePANTHERPTHR13405FAMILY NOT NAMEDcoord: 46..251
coord: 544..1216