angiotensin converting enzyme-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30006268 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of angiotensin converting enzyme-1 vs. Ensembl Human
Match: ACE (angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707]) HSP 1 Score: 333.183 bits (853), Expect = 8.397e-104 Identity = 191/590 (32.37%), Postives = 318/590 (53.90%), Query Frame = 3
Query: 138 PNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
PN+ +DE A K+++ + N A N+ Y TNI + L++ + A + K +A+KF + ++ +KR ++ ++ R + L + I +E Y+ AT C G EP + + + Y+DL W WR+ G I + + + L NQ A +G+ D+ + + ++ + Q L F + Y LH YVR LH++Y N GPIPAH++G+ W+++W N++ ++ + + + T MFK ++ F++SLG+ + +FW +S+ +K + + CH + F NG DFRIK CT +L+DL HEMGHIQYFM Y++L V RE AN GF E GDV+ L+ TP +L + LLS+ + +IN+L+ ALD I FIPF+ ++++ V++GS+ N+ +W + K QG+ PPV RT+ FD GAK+H+ Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG +R W + M+++TG ++++ ++L+++ PL +WL+ +N+ K GW
Sbjct: 66 PNLV---TDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGD-SWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQG---WTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGS-DEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647
BLAST of angiotensin converting enzyme-1 vs. Ensembl Human
Match: AC113554.1 (novel protein) HSP 1 Score: 332.413 bits (851), Expect = 2.285e-103 Identity = 191/590 (32.37%), Postives = 318/590 (53.90%), Query Frame = 3
Query: 138 PNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
PN+ +DE A K+++ + N A N+ Y TNI + L++ + A + K +A+KF + ++ +KR ++ ++ R + L + I +E Y+ AT C G EP + + + Y+DL W WR+ G I + + + L NQ A +G+ D+ + + ++ + Q L F + Y LH YVR LH++Y N GPIPAH++G+ W+++W N++ ++ + + + T MFK ++ F++SLG+ + +FW +S+ +K + + CH + F NG DFRIK CT +L+DL HEMGHIQYFM Y++L V RE AN GF E GDV+ L+ TP +L + LLS+ + +IN+L+ ALD I FIPF+ ++++ V++GS+ N+ +W + K QG+ PPV RT+ FD GAK+H+ Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG +R W + M+++TG ++++ ++L+++ PL +WL+ +N+ K GW
Sbjct: 66 PNLV---TDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGD-SWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQG---WTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGS-DEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647
BLAST of angiotensin converting enzyme-1 vs. Ensembl Human
Match: ACE (angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707]) HSP 1 Score: 334.724 bits (857), Expect = 1.922e-100 Identity = 191/591 (32.32%), Postives = 318/591 (53.81%), Query Frame = 3
Query: 135 YPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
YP + +DE A K+++ + N A N+ Y TNI + L++ + A + K +A+KF + ++ +KR ++ ++ R + L + I +E Y+ AT C G EP + + + Y+DL W WR+ G I + + + L NQ A +G+ D+ + + ++ + Q L F + Y LH YVR LH++Y N GPIPAH++G+ W+++W N++ ++ + + + T MFK ++ F++SLG+ + +FW +S+ +K + + CH + F NG DFRIK CT +L+DL HEMGHIQYFM Y++L V RE AN GF E GDV+ L+ TP +L + LLS+ + +IN+L+ ALD I FIPF+ ++++ V++GS+ N+ +W + K QG+ PPV RT+ FD GAK+H+ Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG +R W + M+++TG ++++ ++L+++ PL +WL+ +N+ K GW
Sbjct: 636 YPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGD-SWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQG---WTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGS-DEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221 HSP 2 Score: 310.457 bits (794), Expect = 1.277e-91 Identity = 166/486 (34.16%), Postives = 270/486 (55.56%), Query Frame = 3
Query: 465 IENIYNTATPCFKGCQPPG---EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+ IY+TA C +P + I + Y L W W NA G ++ L+ + L N+ GF D+ + + + F L + + + Y LH +VR LH+ Y +R+ N GPIPAH++G W++SW N++ ++ K + ++ L++ G H MF+++E F++SL + M +FW+ S+ +K + + CH + F N DFRIK CT + L+++ HEMGHIQY++ Y++L V R AN GF E GDV+ L+ TP +L KIGLL + N S+INYLL AL+ I F+PF ++++ V++G + N +W + K QGI PPV R E +FDAGAK+HV Y R+ S++ Q+ EA+C +GY+GPLHQC + S + GAK ++++ G++R W++ +K + G +L++ LL ++ P+ +WL+++N++ GW
Sbjct: 147 MSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY-WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQ------GWNATH-MFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLD-RVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623
BLAST of angiotensin converting enzyme-1 vs. Ensembl Human
Match: ACE (angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707]) HSP 1 Score: 335.109 bits (858), Expect = 2.966e-100 Identity = 191/591 (32.32%), Postives = 318/591 (53.81%), Query Frame = 3
Query: 135 YPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
YP + +DE A K+++ + N A N+ Y TNI + L++ + A + K +A+KF + ++ +KR ++ ++ R + L + I +E Y+ AT C G EP + + + Y+DL W WR+ G I + + + L NQ A +G+ D+ + + ++ + Q L F + Y LH YVR LH++Y N GPIPAH++G+ W+++W N++ ++ + + + T MFK ++ F++SLG+ + +FW +S+ +K + + CH + F NG DFRIK CT +L+DL HEMGHIQYFM Y++L V RE AN GF E GDV+ L+ TP +L + LLS+ + +IN+L+ ALD I FIPF+ ++++ V++GS+ N+ +W + K QG+ PPV RT+ FD GAK+H+ Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG +R W + M+++TG ++++ ++L+++ PL +WL+ +N+ K GW
Sbjct: 636 YPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGD-SWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQG---WTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGS-DEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221 HSP 2 Score: 310.842 bits (795), Expect = 1.680e-91 Identity = 166/486 (34.16%), Postives = 270/486 (55.56%), Query Frame = 3
Query: 465 IENIYNTATPCFKGCQPPG---EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+ IY+TA C +P + I + Y L W W NA G ++ L+ + L N+ GF D+ + + + F L + + + Y LH +VR LH+ Y +R+ N GPIPAH++G W++SW N++ ++ K + ++ L++ G H MF+++E F++SL + M +FW+ S+ +K + + CH + F N DFRIK CT + L+++ HEMGHIQY++ Y++L V R AN GF E GDV+ L+ TP +L KIGLL + N S+INYLL AL+ I F+PF ++++ V++G + N +W + K QGI PPV R E +FDAGAK+HV Y R+ S++ Q+ EA+C +GY+GPLHQC + S + GAK ++++ G++R W++ +K + G +L++ LL ++ P+ +WL+++N++ GW
Sbjct: 147 MSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY-WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQ------GWNATH-MFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLD-RVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623
BLAST of angiotensin converting enzyme-1 vs. Ensembl Human
Match: ACE2 (angiotensin I converting enzyme 2 [Source:HGNC Symbol;Acc:HGNC:13557]) HSP 1 Score: 276.174 bits (705), Expect = 1.502e-81 Identity = 166/526 (31.56%), Postives = 265/526 (50.38%), Query Frame = 3
Query: 378 VKRSLEMLKI-SSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPG-------EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLAT---------DFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRS-ITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW*T 1901
VK L+ L+ S + + RL I + IY+T K C P EPG+ EI DY++ W +WR+ G ++R L+ E + L+N+ A + + D ++ D+ + + + F+ I Y+ LH YVR L YP+ + G +PAH++G W W N++S+ + + + +D+ +FK +E F+ S+G+ NMT FW+ S +T + CHP + G DFRI MCT + D + HEMGHIQY MAY R AN GF E G++M L+ TP +L+ IGLLS + +EIN+LL AL + +PF +E++ V+ G + ++ K +W++ R+ G+V PV E Y D + +HV+ +++ R+ L+Q+ EA+C + ++GPLH+C NS E G K M++LG + W ++ + G ++N LL ++ PL+ WLK +NK N GW T
Sbjct: 93 VKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTG----KVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQ---AWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNK--NSFVGWST 608
BLAST of angiotensin converting enzyme-1 vs. Ensembl Celegans
Match: acn-1 (Inactive angiotensin-converting enzyme-related protein [Source:UniProtKB/Swiss-Prot;Acc:Q18581]) HSP 1 Score: 149.443 bits (376), Expect = 2.944e-37 Identity = 126/489 (25.77%), Postives = 221/489 (45.19%), Query Frame = 3
Query: 486 ATPCFKGCQPPGEPGIIE---IFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDS-----AEFKLATDFQETNFSQKLRNHFDNIFS----FYKELHGYVRHCLHKYY--PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDE--NIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSD-SFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEI-NYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVA-IGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+T C K PP I+ IF KD L WV++ A ++ + + + + N+ A +GF + + F +++ + F L D I+S FY+ LH Y+R L Y P +K GPIPAH+ GS W + K + E++ + + N T +MF + ++ S G ++ +W SI ++ K M CHP + DFR+K C D + Y Y++ S+ FRE A+ + + P YL L+ + ++++S I N L +L++ +PF I+ + + +++G+V N++N +W+I K +G+ P + DA V+ + TR L SY+ ++ I +A+C +G + S++ K E MKLG++ W K +++++G L++ LL +Y PL WL+ N+ + GW
Sbjct: 286 STICDKDVPPPCALQKIDMDSIFRNEKDASRLQHLWVSYVTAI-AKSKPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSSKVHKAEFD--LNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDWSAHYEQTKPFEE---ESETPEAMLSAFNTQNYTTKKMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWSKDMICHPAAALDMRAPNDFRVKACAQLGEPDFEQAHSLLVQTYYQYLYKDQSLLFREQASPVITDAIANAFAHLSTNPHYLYSQKLVPSEHLDIKDSVIINKLYKESLESFTKLPFTIAADNWRYELFDGTVPKNKLNDRWWEIRNKYEGVRSPQPYNTSNLDALIHNSVSQVHSPATRTLISYVLKFQILKALCP----EGTILSEGCILSEDTTEKLRETMKLGSSITWLKALEMISGKGELDAQPLLEYYEPLINWLRNTNEIDQVVVGW 764
BLAST of angiotensin converting enzyme-1 vs. Ensembl Celegans
Match: acn-1 (Inactive angiotensin-converting enzyme-related protein [Source:UniProtKB/Swiss-Prot;Acc:Q18581]) HSP 1 Score: 149.443 bits (376), Expect = 2.944e-37 Identity = 126/489 (25.77%), Postives = 221/489 (45.19%), Query Frame = 3
Query: 486 ATPCFKGCQPPGEPGIIE---IFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDS-----AEFKLATDFQETNFSQKLRNHFDNIFS----FYKELHGYVRHCLHKYY--PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDE--NIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSD-SFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEI-NYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVA-IGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+T C K PP I+ IF KD L WV++ A ++ + + + + N+ A +GF + + F +++ + F L D I+S FY+ LH Y+R L Y P +K GPIPAH+ GS W + K + E++ + + N T +MF + ++ S G ++ +W SI ++ K M CHP + DFR+K C D + Y Y++ S+ FRE A+ + + P YL L+ + ++++S I N L +L++ +PF I+ + + +++G+V N++N +W+I K +G+ P + DA V+ + TR L SY+ ++ I +A+C +G + S++ K E MKLG++ W K +++++G L++ LL +Y PL WL+ N+ + GW
Sbjct: 286 STICDKDVPPPCALQKIDMDSIFRNEKDASRLQHLWVSYVTAI-AKSKPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSSKVHKAEFD--LNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDWSAHYEQTKPFEE---ESETPEAMLSAFNTQNYTTKKMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWSKDMICHPAAALDMRAPNDFRVKACAQLGEPDFEQAHSLLVQTYYQYLYKDQSLLFREQASPVITDAIANAFAHLSTNPHYLYSQKLVPSEHLDIKDSVIINKLYKESLESFTKLPFTIAADNWRYELFDGTVPKNKLNDRWWEIRNKYEGVRSPQPYNTSNLDALIHNSVSQVHSPATRTLISYVLKFQILKALCP----EGTILSEGCILSEDTTEKLRETMKLGSSITWLKALEMISGKGELDAQPLLEYYEPLINWLRNTNEIDQVVVGW 764
BLAST of angiotensin converting enzyme-1 vs. Ensembl Fly
Match: Acer (gene:FBgn0016122 transcript:FBtr0079685) HSP 1 Score: 291.197 bits (744), Expect = 3.503e-89 Identity = 174/597 (29.15%), Postives = 304/597 (50.92%), Query Frame = 3
Query: 141 NVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEML-KISSRIFDSSTTLRLIDIRFQIENIYNTATPCF----KGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGP------LHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
N C+ E AR++ + NE + R + + Y TN+ N + +I++ ++A L+ ++ + K + ++R E L K+ + ++ L L + ++ Y TAT C C EP I E + +D +LA YW W + +G+ +R F E + L + + +G A++ + +++ +F ++L F + FY++LHGYVR L ++Y P+ G IP ++G+ W +SW+ + + + D++ E+++ TV ++F+L + F+ SLGM + FW S+ + + + CH + F D RIKMCT D + HE+GHIQY++ Y +R + N GF E GDV+ L+ + +L+ IGL+ N S IN L AL IVF+PF ++++Y +V+ + ++ N +W + + G+ PPV RTE FD AKYH+ Y R+ +++FQ+ +A+C +G P L C F SK G + + GN+R+W++ ++ TG T ++ +LL ++ PLY+WLK++N L + GW
Sbjct: 25 NSCSASVLE--ARRFFELENEQLRRRFHEEFLSGYNYNTNVTEANRQAMIEVYARNAELNKRLAQQIKSSDYVQSEDADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYATATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLTRKASQLNGHRSYADYWVQF-YEDPDFERQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVMPAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFV-DVKAEMEKQ--GYTVQKLFELGDQFFQSLGMRALPPSFWNLSVLTRPDDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHELGHIQYYLQYEQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLIE-NGRLDEKSRINQLFKQALSKIVFLPFGYAVDKYRYAVFRNELDESQWNCGFWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLRYFAAHIFQFQFHKALCRKAGQYAPNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEFTGETEMDPAALLEYFEPLYQWLKQENSRLGVPLGW 614
BLAST of angiotensin converting enzyme-1 vs. Ensembl Fly
Match: Acer (gene:FBgn0016122 transcript:FBtr0333416) HSP 1 Score: 291.197 bits (744), Expect = 3.503e-89 Identity = 174/597 (29.15%), Postives = 304/597 (50.92%), Query Frame = 3
Query: 141 NVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEML-KISSRIFDSSTTLRLIDIRFQIENIYNTATPCF----KGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGP------LHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
N C+ E AR++ + NE + R + + Y TN+ N + +I++ ++A L+ ++ + K + ++R E L K+ + ++ L L + ++ Y TAT C C EP I E + +D +LA YW W + +G+ +R F E + L + + +G A++ + +++ +F ++L F + FY++LHGYVR L ++Y P+ G IP ++G+ W +SW+ + + + D++ E+++ TV ++F+L + F+ SLGM + FW S+ + + + CH + F D RIKMCT D + HE+GHIQY++ Y +R + N GF E GDV+ L+ + +L+ IGL+ N S IN L AL IVF+PF ++++Y +V+ + ++ N +W + + G+ PPV RTE FD AKYH+ Y R+ +++FQ+ +A+C +G P L C F SK G + + GN+R+W++ ++ TG T ++ +LL ++ PLY+WLK++N L + GW
Sbjct: 25 NSCSASVLE--ARRFFELENEQLRRRFHEEFLSGYNYNTNVTEANRQAMIEVYARNAELNKRLAQQIKSSDYVQSEDADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYATATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLTRKASQLNGHRSYADYWVQF-YEDPDFERQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVMPAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFV-DVKAEMEKQ--GYTVQKLFELGDQFFQSLGMRALPPSFWNLSVLTRPDDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHELGHIQYYLQYEQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLIE-NGRLDEKSRINQLFKQALSKIVFLPFGYAVDKYRYAVFRNELDESQWNCGFWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLRYFAAHIFQFQFHKALCRKAGQYAPNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEFTGETEMDPAALLEYFEPLYQWLKQENSRLGVPLGW 614
BLAST of angiotensin converting enzyme-1 vs. Ensembl Fly
Match: Ance-3 (gene:FBgn0032536 transcript:FBtr0343641) HSP 1 Score: 278.87 bits (712), Expect = 1.263e-82 Identity = 165/526 (31.37%), Postives = 277/526 (52.66%), Query Frame = 3
Query: 381 KRSLEMLKISSRIFDSSTTLRLIDIRFQIEN----IYNTATPCFKGCQPPGE------PGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKL----TVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGY------KGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+R L + S + ++ L ++D ++ N +YN+A C Q P + P + +I + +D+D+L WV + G +R+ + + +++ + A + + E+ ++ NF Q + ++ I Y+ LH YVR L YY P+R N+ PIP+HI+G+ + +SW NV IL RK ID + T MF+L+E F++S+ M + +F++ SI ++ + + C P + F N DFR+K+CT + + L S+ HEM HIQYF+ YR+L FR AN F + GD +GL+ TP +L+ +GLL +++ + +INYL T A+D + F+PFA+S++ + V++G+ MN YW++ K GI PPV R+E FD GAKYH+ Y ++ FS + Q+ I+ +C SG + PLHQC + G +M G ++ W++ ++ L+ +L ++ PL EWL+++N N GW
Sbjct: 279 RRLYRQLMLQSEVGPNALPLDVLDRYNRLLNEMLFLYNSAEIC--AYQQPFQCDLHYIPQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVNNVTNGGEYWYLA-YESGNFRQDMDIVWEQIRPLYEGLHAYVRRKLRDYYGPDRINRIAPIPSHILGNMYGQSWSNVLDILIPYPG-------RKLIDVTPRMVEQGYTPQLMFQLAEEFFTSINMSAVGPEFYRNSIFEQPLDRRVLCEPSAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRHLPKIFRNGANPAFHQAVGDAIGLSVSTPRHLQTLGLLQRSLDE-SSYDINYLFTMAIDKVAFLPFALSLDNWRYDVFSGNANKRTMNCHYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIPYIKYFFSTVLQFQIYRGLCRESGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEETLREGRLDGTALREYFAPLEEWLRQENLRTNEYVGW 793
BLAST of angiotensin converting enzyme-1 vs. Ensembl Fly
Match: Ance-3 (gene:FBgn0032536 transcript:FBtr0100327) HSP 1 Score: 278.87 bits (712), Expect = 1.263e-82 Identity = 165/526 (31.37%), Postives = 277/526 (52.66%), Query Frame = 3
Query: 381 KRSLEMLKISSRIFDSSTTLRLIDIRFQIEN----IYNTATPCFKGCQPPGE------PGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKL----TVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGY------KGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+R L + S + ++ L ++D ++ N +YN+A C Q P + P + +I + +D+D+L WV + G +R+ + + +++ + A + + E+ ++ NF Q + ++ I Y+ LH YVR L YY P+R N+ PIP+HI+G+ + +SW NV IL RK ID + T MF+L+E F++S+ M + +F++ SI ++ + + C P + F N DFR+K+CT + + L S+ HEM HIQYF+ YR+L FR AN F + GD +GL+ TP +L+ +GLL +++ + +INYL T A+D + F+PFA+S++ + V++G+ MN YW++ K GI PPV R+E FD GAKYH+ Y ++ FS + Q+ I+ +C SG + PLHQC + G +M G ++ W++ ++ L+ +L ++ PL EWL+++N N GW
Sbjct: 279 RRLYRQLMLQSEVGPNALPLDVLDRYNRLLNEMLFLYNSAEIC--AYQQPFQCDLHYIPQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVNNVTNGGEYWYLA-YESGNFRQDMDIVWEQIRPLYEGLHAYVRRKLRDYYGPDRINRIAPIPSHILGNMYGQSWSNVLDILIPYPG-------RKLIDVTPRMVEQGYTPQLMFQLAEEFFTSINMSAVGPEFYRNSIFEQPLDRRVLCEPSAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRHLPKIFRNGANPAFHQAVGDAIGLSVSTPRHLQTLGLLQRSLDE-SSYDINYLFTMAIDKVAFLPFALSLDNWRYDVFSGNANKRTMNCHYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIPYIKYFFSTVLQFQIYRGLCRESGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEETLREGRLDGTALREYFAPLEEWLRQENLRTNEYVGW 793
BLAST of angiotensin converting enzyme-1 vs. Ensembl Fly
Match: Ance (gene:FBgn0012037 transcript:FBtr0080553) HSP 1 Score: 273.092 bits (697), Expect = 1.529e-82 Identity = 170/593 (28.67%), Postives = 310/593 (52.28%), Query Frame = 3
Query: 162 DENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEML-KISSRIFDSSTTLRLIDIRFQIENIYNTATPC-FKG---CQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSG------YKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW*T 1901
+E A+++L+ +N+ + + N + Y +NI N ++ ++ + A ++ KF+ + ++S +KR + L K+ L+D +E+ + C +K C +P I E+ ++ +D+++LA YW + + G+ +R+ F + L + A + F AE L ++++ F Q+L + F +I Y+++HGYVR L K+Y + +++GPIP H++G+ W++ W + I+ + D+ E+++ T +MF++ + F++S+ + + FW +SI +K + + CH + F D RIK CT L ++ HE+GHIQYF+ Y++ +R AN GF E GDV+ L+ TP +L KIGLL + + + IN L +ALD IVF+PFA ++++Y S++ G V N +W + + GI PPV R+E FDA AKYH++ Y R+L S++ Q+ +++ C +G + PL C + S GA M+ +G ++ W ++ G ++ ++ ++ PL WL+ +N + N+ GW T
Sbjct: 21 EEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWL-DEYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIVSPFPEKPL-VDVSAEMEKQ--GYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRD-DEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTT 608
BLAST of angiotensin converting enzyme-1 vs. Ensembl Zebrafish
Match: ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:ZFIN;Acc:ZDB-GENE-030131-1826]) HSP 1 Score: 340.502 bits (872), Expect = 2.394e-102 Identity = 197/597 (33.00%), Postives = 317/597 (53.10%), Query Frame = 3
Query: 129 EPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNIN----GNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTL-RLIDIRFQIENIYNTATPC-FKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
E YP +DE A+++L N N ++ Y T+I N L++ ++M + I + VKR L L R S+ L ++ +E +Y+ AT C K P +P + +I +DYD+L W WRNA+G IR+ + + L N A +G D+ F + ++ F Q L + ++ Y +H YVR L+K Y P R N GPIPAH++G+ W+++W + ++ + I + T MF+ S+ F++SLG+ M +FW +S+ +K + + CH + F N DFRIK CTV + DL ++ HEMGH+QYF+ Y++ + FR+ AN GF E GDV+ L+ TP +L+ IGLL +N S IN+L++ ALD I F+PF ++++ V++G + ++E NK +W++ K QG+ PPV RTE FD GAK+H+ Y R+ S++ Q+ + +C+ +G+KGPLH C + SKE G ++MK+G ++ W + MKI+TG ++ L+ ++ PL EWL+K+N++ GW
Sbjct: 662 EGYPEDIGKITDEMQAKQFLDEYNSTAEEVWNAYTESSWTYNTDITEAHKDNMLQKNLEMANHTKIYGLEARKYDTSDFQDES----VKRILSKLSDLERAALSAEDLVEYNNLLASMETLYSVATVCKDKSNCLPLDPDLNKIMAESRDYDELLFAWQGWRNASGREIRDSYKRYVELANSAAKSNGHTDNGAFWRSL-YETPTFEQDLEALWKDLEPLYLSVHAYVRRALYKKYGPERINLKGPIPAHLLGNMWAQTWSGIMDLVNPYPDATQVDATPAMIAQG---WTPKRMFEESDRFFTSLGLLPMPPEFWNKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPISFRDGANPGFHEAIGDVLALSVATPKHLQSIGLLDKVEDNAE-STINFLMSIALDKIAFLPFGYLMDQWRWKVFDGRISSSEYNKEWWNLRMKYQGLCPPVPRTEKDFDPGAKFHIPANVPYIRYFVSFVIQFQFHKGLCDAAGHKGPLHNCDIYQSKEAGKLLSDVMKMGFSKPWPEAMKIITGQPKMSVQPLMEYFKPLIEWLEKENEKNGDVLGW 1249 HSP 2 Score: 314.694 bits (805), Expect = 5.118e-93 Identity = 166/488 (34.02%), Postives = 277/488 (56.76%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKGCQPPGE-----PGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I Q+++IY+TA K C P E P + EI + Y L W W N++G +++L+ E + + N+ + GF D+ E+ + ++ F Q L N F + Y+ LH +VR L+ YY P N GPIPAH++G+ WS++W+N+++++ + + I + G H MF+++E F++SLG+ M +FW +S+ +K + + CH + F N DFRIK CT ++ L ++ HEMGH++Y++ Y++ V FR AN GF E GDV+ L+ TP +L I LL + + S+INYLL AL+ I F+PF I+++ SV++G + N +W + K QGI PP RTE +FDAG KYH+ Y R+ S++ Q+ E +C +G+ GPLH+C + S+E GA +++K G++ W + ++ GT +++ L++++ P+ WL+++N++ GW
Sbjct: 173 ILSQMDSIYSTA----KVCPSPEECWSLEPELQEIMATSRSYKRLLYAWEGWHNSSGVPLKSLYAEFVKISNKASQMDGFKDTGEY-WRSWYESPTFKQDLENLFKQLEPLYQNLHAFVRRKLYDYYGPKYINLKGPIPAHLLGNMWSQTWNNIYNMMIPFPNRPNVDVTNTMIAK--GYNATH-MFRVAEEFFTSLGLLEMPPEFWDKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVSFRRGANPGFHEAIGDVLSLSVSTPKHLHSIDLLD-QLTDDAESDINYLLKMALEKIAFLPFGYLIDQWRWSVFSGETPPDRYNADWWYLRTKYQGICPPTRRTEEHFDAGGKYHIPGNTPYIRYFVSFILQFQFHEKLCKEAGHTGPLHKCDIYKSREAGAVLEKVLKAGSSEPWTQVLQEALGTDKMDATPLMSYFLPVTTWLREQNEKTGETLGW 651
BLAST of angiotensin converting enzyme-1 vs. Ensembl Zebrafish
Match: ace2 (angiotensin I converting enzyme 2 [Source:ZFIN;Acc:ZDB-GENE-041114-6]) HSP 1 Score: 295.819 bits (756), Expect = 2.801e-89 Identity = 186/610 (30.49%), Postives = 306/610 (50.16%), Query Frame = 3
Query: 141 NVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSW-----KMHXXXXXXXXXXXXSPWVKRSLEMLKI-SSRIFDSSTTLRLIDIRFQIENIYNTATPC----FKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKA-----TDSGFHDSAEFKLATD----FQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHE------MFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+V + E+ AR++L + +E + ++ Y T+I+ N K+ A W KM ++ + + P +K L+ L+ S L +I ++ IYNTAT C CQ EPG+ I +DYD+ W WR ATG ++R L+ + ++L+N+ A D G + +++ D + + R + I YKELH YVR L YP +PAH++G W W N++ ++ I D R +ID + V + +FK +E F+ S+ M M D FW S+ K + + + CHP + N DFRIKMCT ++ D ++ HEMGH QY MAYRN R+ AN GF E G++M L+ TP++L+ +GLL ++ ++IN+LL AL + +PF +EE+ V+ + +E + +W + R+ G+ V R E Y D A +HV+ +++ R+ ++Q+ EA+C +G+ GPL++C NS + G K M++LG + +W + ++ + GTT ++S LL ++ L EWLK++N++ N GW
Sbjct: 13 SVACCQTVEDRAREFLNKFDEEASDIMYQYTLASWAYNTDISQENAD-----KEAEAYAIWSEYYNKMSEESNAYPIDQISDPIIKMQLQKLQDKGSGALSPDKASELRNIMSEMSTIYNTATVCKIDDPTDCQT-LEPGLESIMAESRDYDERLHVWEGWRVATGMKMRPLYEKYVDLKNEAAKLNNYEDHGDYWRGDYETIDDPKYSYSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVYPGHIGSDACLPAHLLGDMWGRFWTNLYPLM------IPYPD-RPDID--VSSAMVEQGWDEIRLFKEAEKFFMSVNMPAMFDNFWNNSMFIKPEERDVVCHPTAWDMGNRKDFRIKMCTKVNMDDFLTVHHEMGHNQYQMAYRNHPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPSDFKQDYETDINFLLKQALTIVGTLPFTYMLEEWRWQVFKAKIPKDEWMQQWWQMKRELVGVAEAVPRDETYCDPPALFHVSGDYSFIRYFTRTIYQFQFQEALCKAAGHTGPLYKCDITNSTKAGDKLRHMLELGRSMSWTRALEEVAGTTKMDSQPLLHYFSTLMEWLKEENQKNNRVPGW 607
BLAST of angiotensin converting enzyme-1 vs. Ensembl Zebrafish
Match: ace2 (angiotensin I converting enzyme 2 [Source:ZFIN;Acc:ZDB-GENE-041114-6]) HSP 1 Score: 295.819 bits (756), Expect = 6.011e-89 Identity = 186/610 (30.49%), Postives = 306/610 (50.16%), Query Frame = 3
Query: 141 NVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSW-----KMHXXXXXXXXXXXXSPWVKRSLEMLKI-SSRIFDSSTTLRLIDIRFQIENIYNTATPC----FKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKA-----TDSGFHDSAEFKLATD----FQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHE------MFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+V + E+ AR++L + +E + ++ Y T+I+ N K+ A W KM ++ + + P +K L+ L+ S L +I ++ IYNTAT C CQ EPG+ I +DYD+ W WR ATG ++R L+ + ++L+N+ A D G + +++ D + + R + I YKELH YVR L YP +PAH++G W W N++ ++ I D R +ID + V + +FK +E F+ S+ M M D FW S+ K + + + CHP + N DFRIKMCT ++ D ++ HEMGH QY MAYRN R+ AN GF E G++M L+ TP++L+ +GLL ++ ++IN+LL AL + +PF +EE+ V+ + +E + +W + R+ G+ V R E Y D A +HV+ +++ R+ ++Q+ EA+C +G+ GPL++C NS + G K M++LG + +W + ++ + GTT ++S LL ++ L EWLK++N++ N GW
Sbjct: 13 SVACCQTVEDRAREFLNKFDEEASDIMYQYTLASWAYNTDISQENAD-----KEAEAYAIWSEYYNKMSEESNAYPIDQISDPIIKMQLQKLQDKGSGALSPDKASELRNIMSEMSTIYNTATVCKIDDPTDCQTL-EPGLESIMAESRDYDERLHVWEGWRVATGMKMRPLYEKYVDLKNEAAKLNNYEDHGDYWRGDYETIDDPKYSYSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVYPGHIGSDACLPAHLLGDMWGRFWTNLYPLM------IPYPD-RPDID--VSSAMVEQGWDEIRLFKEAEKFFMSVNMPAMFDNFWNNSMFIKPEERDVVCHPTAWDMGNRKDFRIKMCTKVNMDDFLTVHHEMGHNQYQMAYRNHPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPSDFKQDYETDINFLLKQALTIVGTLPFTYMLEEWRWQVFKAKIPKDEWMQQWWQMKRELVGVAEAVPRDETYCDPPALFHVSGDYSFIRYFTRTIYQFQFQEALCKAAGHTGPLYKCDITNSTKAGDKLRHMLELGRSMSWTRALEEVAGTTKMDSQPLLHYFSTLMEWLKEENQKNNRVPGW 607
BLAST of angiotensin converting enzyme-1 vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634]) HSP 1 Score: 350.517 bits (898), Expect = 9.976e-112 Identity = 177/485 (36.49%), Postives = 286/485 (58.97%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKG---CQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPN-RFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I +E IY+ A C G C P +P + EI + +DYD+L W WR+A+G +IR + + L N+ A +G++D+ + + ++ + +D + Y LH YVR L+K Y + R N GPIPAH++G+ W++SW N++ +L + N + + + T MF+ S++F+ SLG+ M +FW +S+ +K K + + CH + F N DFRIK CTV ++ DL ++ HEMGH+QYF+ Y++ + FRE AN GF E GDV+ L+ TP +L+ IGLL +N S+INYL++ ALD I F+PF ++++ V++G ++E N+ +W++ K QG+VPPV RTEN FD GAK+H+ Y R+ S++ Q+ EA+C + +GPLH+C + S + G + MKLGN++ W + M+ +TG ++++ +LL ++ PL +WL K+N + GW
Sbjct: 51 ITSDMETIYSVAKVCKDGNTNCHP-LDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVP-----YPNAAQVDATPAMINWTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDN-PESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 527
BLAST of angiotensin converting enzyme-1 vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634]) HSP 1 Score: 350.903 bits (899), Expect = 2.752e-106 Identity = 177/485 (36.49%), Postives = 285/485 (58.76%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKG---CQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPN-RFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I +E IY+ A C G C P +P + EI + +DYD+L W WR+A+G +IR + + L N+ A +G++D+ + + ++ + +D + Y LH YVR L+K Y + R N GPIPAH++G+ W++SW N++ +L + I +N T MF+ S++F+ SLG+ M +FW +S+ +K K + + CH + F N DFRIK CTV ++ DL ++ HEMGH+QYF+ Y++ + FRE AN GF E GDV+ L+ TP +L+ IGLL + + S+INYL++ ALD I F+PF ++++ V++G ++E N+ +W++ K QG+VPPV RTEN FD GAK+H+ Y R+ S++ Q+ EA+C + +GPLH+C + S + G + MKLGN++ W + M+ +TG ++++ +LL ++ PL +WL K+N + GW
Sbjct: 712 ITSDMETIYSVAKVCKDGNTNCHP-LDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVPYPNAAQVDATPAMIAKN---WTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLD-KVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1190 HSP 2 Score: 304.294 bits (778), Expect = 2.267e-89 Identity = 161/493 (32.66%), Postives = 274/493 (55.58%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKGCQPPG--------EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKC--HKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I ++++IY+TA C PP EP I EI + Y L W W N+ G ++ ++ + L N+ G+ D+ + + + F + L + + Y LH +VR L++ Y ++ N GPIPAH+ G+ WS+ W+N++ ++ NI + +E N MF++SE F++SLG+ M +FW++S+ +K + + CH + F N DFRIK CT ++ L ++ HEMGH++Y++ Y++ V +R AN GF E GDV+ L+ TP +L+ IGLL T + N + S+INYLL AL+ I F+PF I+++ +V++G N +W++ K QGI PP+ R +N FDAGAKYH+ Y R+ S++ Q+ +A+C + + GPLH C + S+E G ++++ G++++W++ +K +TG+ ++ LL ++ P+ +WL ++N + N GW
Sbjct: 114 ILSEMDSIYSTAKVC-----PPNATAKCWSLEPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAY-WRSWYASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMMIPFPDKTNIDVTNTMREKGWN-----ATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDT-VTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 594
BLAST of angiotensin converting enzyme-1 vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634]) HSP 1 Score: 350.903 bits (899), Expect = 3.473e-106 Identity = 177/485 (36.49%), Postives = 285/485 (58.76%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKG---CQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPN-RFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I +E IY+ A C G C P +P + EI + +DYD+L W WR+A+G +IR + + L N+ A +G++D+ + + ++ + +D + Y LH YVR L+K Y + R N GPIPAH++G+ W++SW N++ +L + I +N T MF+ S++F+ SLG+ M +FW +S+ +K K + + CH + F N DFRIK CTV ++ DL ++ HEMGH+QYF+ Y++ + FRE AN GF E GDV+ L+ TP +L+ IGLL + + S+INYL++ ALD I F+PF ++++ V++G ++E N+ +W++ K QG+VPPV RTEN FD GAK+H+ Y R+ S++ Q+ EA+C + +GPLH+C + S + G + MKLGN++ W + M+ +TG ++++ +LL ++ PL +WL K+N + GW
Sbjct: 737 ITSDMETIYSVAKVCKDGNTNCHP-LDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVPYPNAAQVDATPAMIAKN---WTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLD-KVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1215 HSP 2 Score: 304.294 bits (778), Expect = 2.358e-89 Identity = 161/493 (32.66%), Postives = 274/493 (55.58%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKGCQPPG--------EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKC--HKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I ++++IY+TA C PP EP I EI + Y L W W N+ G ++ ++ + L N+ G+ D+ + + + F + L + + Y LH +VR L++ Y ++ N GPIPAH+ G+ WS+ W+N++ ++ NI + +E N MF++SE F++SLG+ M +FW++S+ +K + + CH + F N DFRIK CT ++ L ++ HEMGH++Y++ Y++ V +R AN GF E GDV+ L+ TP +L+ IGLL T + N + S+INYLL AL+ I F+PF I+++ +V++G N +W++ K QGI PP+ R +N FDAGAKYH+ Y R+ S++ Q+ +A+C + + GPLH C + S+E G ++++ G++++W++ +K +TG+ ++ LL ++ P+ +WL ++N + N GW
Sbjct: 139 ILSEMDSIYSTAKVC-----PPNATAKCWSLEPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAY-WRSWYASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMMIPFPDKTNIDVTNTMREKGWN-----ATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDT-VTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 619
BLAST of angiotensin converting enzyme-1 vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634]) HSP 1 Score: 350.903 bits (899), Expect = 4.148e-106 Identity = 177/485 (36.49%), Postives = 285/485 (58.76%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKG---CQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPN-RFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I +E IY+ A C G C P +P + EI + +DYD+L W WR+A+G +IR + + L N+ A +G++D+ + + ++ + +D + Y LH YVR L+K Y + R N GPIPAH++G+ W++SW N++ +L + I +N T MF+ S++F+ SLG+ M +FW +S+ +K K + + CH + F N DFRIK CTV ++ DL ++ HEMGH+QYF+ Y++ + FRE AN GF E GDV+ L+ TP +L+ IGLL + + S+INYL++ ALD I F+PF ++++ V++G ++E N+ +W++ K QG+VPPV RTEN FD GAK+H+ Y R+ S++ Q+ EA+C + +GPLH+C + S + G + MKLGN++ W + M+ +TG ++++ +LL ++ PL +WL K+N + GW
Sbjct: 730 ITSDMETIYSVAKVCKDGNTNCHP-LDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVPYPNAAQVDATPAMIAKN---WTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLD-KVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1208 HSP 2 Score: 304.294 bits (778), Expect = 3.151e-89 Identity = 161/493 (32.66%), Postives = 274/493 (55.58%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKGCQPPG--------EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKC--HKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I ++++IY+TA C PP EP I EI + Y L W W N+ G ++ ++ + L N+ G+ D+ + + + F + L + + Y LH +VR L++ Y ++ N GPIPAH+ G+ WS+ W+N++ ++ NI + +E N MF++SE F++SLG+ M +FW++S+ +K + + CH + F N DFRIK CT ++ L ++ HEMGH++Y++ Y++ V +R AN GF E GDV+ L+ TP +L+ IGLL T + N + S+INYLL AL+ I F+PF I+++ +V++G N +W++ K QGI PP+ R +N FDAGAKYH+ Y R+ S++ Q+ +A+C + + GPLH C + S+E G ++++ G++++W++ +K +TG+ ++ LL ++ P+ +WL ++N + N GW
Sbjct: 132 ILSEMDSIYSTAKVC-----PPNATAKCWSLEPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAY-WRSWYASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMMIPFPDKTNIDVTNTMREKGWN-----ATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDT-VTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 612
BLAST of angiotensin converting enzyme-1 vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634]) HSP 1 Score: 350.517 bits (898), Expect = 5.226e-106 Identity = 176/485 (36.29%), Postives = 286/485 (58.97%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKG---CQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPN-RFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I +E IY+ A C G C P +P + EI + +DYD+L W WR+A+G +IR + + L N+ A +G++D+ + + ++ + +D + Y LH YVR L+K Y + R N GPIPAH++G+ W++SW N++ +L + N + + + T MF+ S++F+ SLG+ M +FW +S+ +K K + + CH + F N DFRIK CTV ++ DL ++ HEMGH+QYF+ Y++ + FRE AN GF E GDV+ L+ TP +L+ IGLL + + S+INYL++ ALD I F+PF ++++ V++G ++E N+ +W++ K QG+VPPV RTEN FD GAK+H+ Y R+ S++ Q+ EA+C + +GPLH+C + S + G + MKLGN++ W + M+ +TG ++++ +LL ++ PL +WL K+N + GW
Sbjct: 737 ITSDMETIYSVAKVCKDGNTNCHP-LDPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVP-----YPNAAQVDATPAMINWTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLD-KVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1213 HSP 2 Score: 303.908 bits (777), Expect = 3.758e-89 Identity = 161/493 (32.66%), Postives = 274/493 (55.58%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKGCQPPG--------EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKC--HKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I ++++IY+TA C PP EP I EI + Y L W W N+ G ++ ++ + L N+ G+ D+ + + + F + L + + Y LH +VR L++ Y ++ N GPIPAH+ G+ WS+ W+N++ ++ NI + +E N MF++SE F++SLG+ M +FW++S+ +K + + CH + F N DFRIK CT ++ L ++ HEMGH++Y++ Y++ V +R AN GF E GDV+ L+ TP +L+ IGLL T + N + S+INYLL AL+ I F+PF I+++ +V++G N +W++ K QGI PP+ R +N FDAGAKYH+ Y R+ S++ Q+ +A+C + + GPLH C + S+E G ++++ G++++W++ +K +TG+ ++ LL ++ P+ +WL ++N + N GW
Sbjct: 137 ILSEMDSIYSTAKVC-----PPNATAKCWSLEPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAY-WRSWYASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMMIPFPDKTNIDVTNTMREKGWN-----ATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDT-VTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 617
BLAST of angiotensin converting enzyme-1 vs. Ensembl Mouse
Match: Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:MGI Symbol;Acc:MGI:87874]) HSP 1 Score: 330.487 bits (846), Expect = 7.020e-103 Identity = 188/597 (31.49%), Postives = 325/597 (54.44%), Query Frame = 3
Query: 117 KSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
++ ++ + N +DE A ++++ + N A N++Y TNI + L++ + + + K +AK F + F++ +KR ++ L+ R L + I +E Y+ + C+ G P EP + + + Y++L W +WR+ G I F + + N+ A +G+ D+ + + ++ N Q L + + Y LH YVR LH++Y + + N GPIPAH++G+ W+++W N++ ++ + + I + T +FK +++F++SLG+ + +FW +S+ +K + + CHP + F NG DFRIK CT +++DL HEMGHIQYFM Y++L V FRE AN GF E GD+M L+ TP +L + LLST + +IN+L+ ALD I FIPF+ I+++ V++GS+ N+ +W + K QG+ PPV R++ FD G+K+HV Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG ++ W + MK++TG ++++ +++ ++ PL EWL +N+ GW
Sbjct: 55 QATIDQTTQIPNLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPLEPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGD-SWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPNIDATEAMIKQG---WTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYE-YDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 646
BLAST of angiotensin converting enzyme-1 vs. Ensembl Mouse
Match: Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:MGI Symbol;Acc:MGI:87874]) HSP 1 Score: 332.413 bits (851), Expect = 3.944e-101 Identity = 189/591 (31.98%), Postives = 322/591 (54.48%), Query Frame = 3
Query: 135 YPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
YP + +DE A ++++ + N A N++Y TNI + L++ + + + K +AK F + F++ +KR ++ L+ R L + I +E Y+ + C+ G P EP + + + Y++L W +WR+ G I F + + N+ A +G+ D+ + + ++ N Q L + + Y LH YVR LH++Y + + N GPIPAH++G+ W+++W N++ ++ + + I + T +FK +++F++SLG+ + +FW +S+ +K + + CHP + F NG DFRIK CT +++DL HEMGHIQYFM Y++L V FRE AN GF E GD+M L+ TP +L + LLST + +IN+L+ ALD I FIPF+ I+++ V++GS+ N+ +W + K QG+ PPV R++ FD G+K+HV Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG ++ W + MK++TG ++++ +++ ++ PL EWL +N+ GW
Sbjct: 408 YPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPLEPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGD-SWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPNIDATEAMIKQG---WTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYE-YDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 993 HSP 2 Score: 292.352 bits (747), Expect = 2.664e-86 Identity = 146/401 (36.41%), Postives = 242/401 (60.35%), Query Frame = 3
Query: 711 FQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
++ +F + L + + + Y LH YVR LH+ Y +++ N GPIPAH++G W++SW N++ ++ K + ++ ++K G H MF++SE F++SLG+ M +FW S+ +K + + CH + F N DFRIK CT ++ L ++ HEMGH+QY++ Y++L V R AN GF E GDV+ L+ TPA+L KIGLL N++ S+INYLL AL+ I F+PF ++++ V++G + N +W + K QGI PPV R E +FDAGAK+H+ Y R+ S++ Q+ +A+C +G++GPLHQC + S + GAK ++++ G +R W++ +K L G+ +L++ +LL ++ P+ +WL+++N+ GW
Sbjct: 3 YESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMVQK------GWNATH-MFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIE-SDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGW 395
BLAST of angiotensin converting enzyme-1 vs. Ensembl Mouse
Match: Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:MGI Symbol;Acc:MGI:87874]) HSP 1 Score: 332.413 bits (851), Expect = 1.882e-99 Identity = 189/591 (31.98%), Postives = 322/591 (54.48%), Query Frame = 3
Query: 135 YPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
YP + +DE A ++++ + N A N++Y TNI + L++ + + + K +AK F + F++ +KR ++ L+ R L + I +E Y+ + C+ G P EP + + + Y++L W +WR+ G I F + + N+ A +G+ D+ + + ++ N Q L + + Y LH YVR LH++Y + + N GPIPAH++G+ W+++W N++ ++ + + I + T +FK +++F++SLG+ + +FW +S+ +K + + CHP + F NG DFRIK CT +++DL HEMGHIQYFM Y++L V FRE AN GF E GD+M L+ TP +L + LLST + +IN+L+ ALD I FIPF+ I+++ V++GS+ N+ +W + K QG+ PPV R++ FD G+K+HV Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG ++ W + MK++TG ++++ +++ ++ PL EWL +N+ GW
Sbjct: 641 YPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPLEPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGD-SWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPNIDATEAMIKQG---WTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYE-YDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1226 HSP 2 Score: 312.768 bits (800), Expect = 2.503e-92 Identity = 164/486 (33.74%), Postives = 274/486 (56.38%), Query Frame = 3
Query: 465 IENIYNTATPCFKGCQPPG---EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+ IY+T CF +P + I + Y L W W +A G ++ L+ + + N+ F D+ F + ++ +F + L + + + Y LH YVR LH+ Y +++ N GPIPAH++G W++SW N++ ++ K + ++ ++K G H MF++SE F++SLG+ M +FW S+ +K + + CH + F N DFRIK CT ++ L ++ HEMGH+QY++ Y++L V R AN GF E GDV+ L+ TPA+L KIGLL N++ S+INYLL AL+ I F+PF ++++ V++G + N +W + K QGI PPV R E +FDAGAK+H+ Y R+ S++ Q+ +A+C +G++GPLHQC + S + GAK ++++ G +R W++ +K L G+ +L++ +LL ++ P+ +WL+++N+ GW
Sbjct: 152 MSRIYSTGKVCFPNKTATCWSLDPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAF-WRSWYESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMVQK------GWNATH-MFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIE-SDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGW 628
BLAST of angiotensin converting enzyme-1 vs. Ensembl Mouse
Match: Ace3 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 [Source:MGI Symbol;Acc:MGI:3644400]) HSP 1 Score: 308.145 bits (788), Expect = 2.256e-94 Identity = 184/586 (31.40%), Postives = 309/586 (52.73%), Query Frame = 3
Query: 150 NGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLK-ISSRIFDSSTTLRLIDIRFQIENIYNTATPCF-KGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
N E A+ +LQ + N + Y TNI N + +++ + + +A+ FR F + VKR L L+ I + L + +E YN A C +G EP + EI +D +L W WR+A G ++R +F + + L N+ A +G+ D + ++ + L + + Y LH YVR L++YY P + GPIPAH++G+ W++SW+N+ ++ E D+ + I +MF+ + F++S+GM FW +S+ +K + ++CH S +F DFR+K CT L+DL S+FH+MGHIQYF+ Y+NLSV ++E A+ F E G V+ L+ + YL GLLS + E+N+LL AL+ I FIPF+ ++++ +++G++ N+ +W+ K QG+ PPV R+++ FD GAK+H+ Y R+ + Q+ + EA+C SG+ GPLHQC +NSK G +++KLG++R WR+ ++ +TG +++++ + LT++ PL +WL +N + GW
Sbjct: 30 NDFYSEAQAKLFLQFYEQTAQVVLNEFMEATWNYVTNITKQNQKNMLQKEADRSQFMLYFSTRARMFRTDHFLNQDVKRMLRKLQNIDKSALPTEDLLEYNRLLTYMETAYNRAEVCLDEGPCLTLEPDLQEIMATSRDQKELLWAWQGWRDAVGRQLRPVFEDYVRLSNKAAQYNGYKDMGAL-WRSKYESDTLEEDLEQLYKELQPLYLNLHAYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILDLVLPYPTKAPE-DITAIM--KIQHWRPEKMFEEANLFFTSMGMLPAPPAFWIKSMMEKPADGREVECHTSSWNFYKFNDFRVKKCTEVTLEDLLSVFHQMGHIQYFLQYQNLSVIYQEGASPAFEEAVGSVIALSVSSHKYLLARGLLSQPHQD-SEEEVNFLLGIALEKIAFIPFSYLVDKFRWKIFDGTISKITYNQEWWNFRLKYQGLCPPVPRSDDDFDPGAKFHIPANVPYIRYFLGLILQFQLHEALCEASGHVGPLHQCDNYNSKVAGKILGDLLKLGSSRPWREVLQEVTGESNISTKAFLTYFKPLMDWLVTENVKQGDTLGW 610
BLAST of angiotensin converting enzyme-1 vs. Ensembl Mouse
Match: Ace2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [Source:MGI Symbol;Acc:MGI:1917258]) HSP 1 Score: 279.641 bits (714), Expect = 5.228e-83 Identity = 173/577 (29.98%), Postives = 292/577 (50.61%), Query Frame = 3
Query: 237 VNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKIS-SRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPG-------EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHD---------SAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSI----LKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRS-ITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW*T 1901
++ Y TNI N +++ + K + + A+ F L+ ++P +KR L+ L+ S S + +L I + IY+T K C P EPG+ EI DY+ W WR G ++R L+ E + L+N+ A + ++D AE ++ + + F I Y+ LH YVR L YP+ + +G +PAH++G W W N++ + +K + ++ + + + D +F+ +E F+ S+G+ +MT FW S +T+ + + CHP + +G DFRIKMCT + + + HEMGHIQY MAY R AN GF E G++M L+ TP +L+ IGLL ++ +EIN+LL AL + +PF +E++ V+ G + + K +W++ R+ G+V P+ E Y D + +HV+ +++ R+ ++Q+ EA+C + Y G LH+C NS E G K L+M+ LGN+ W K ++ + G +++ LL ++ PL++WLK++N+ N GW T
Sbjct: 46 ASWNYNTNITEENAQKMSEAAAKWSAFYEEQSKTAQSFSLQEIQTPIIKRQLQALQQSGSSALSADKNKQLNTILNTMSTIYSTG----KVCNPKNPQECLLLEPGLDEIMATSTDYNSRLWAWEGWRAEVGKQLRPLYEEYVVLKNEMARANNYNDYGDYWRGDYEAEGADGYNYNRNQLIEDVERTFAEIKPLYEHLHAYVRRKLMDTYPSYISPTGCLPAHLLGDMWGRFWTNLYPLTVPFAQKPNIDVTDAMMNQGWD-------AERIFQEAEKFFVSVGLPHMTQGFWANSMLTEPADGRKVVCHPTAWDLGHG-DFRIKMCTKVTMDNFLTAHHEMGHIQYDMAYARQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLPSDFQEDSETEINFLLKQALTIVGTLPFTYMLEKWRWMVFRGEIPKEQWMKKWWEMKREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRYYTRTIYQFQFQEALCQAAKYNGSLHKCDISNSTEAGQKLLKMLSLGNSEPWTKALENVVGARNMDVKPLLNYFQPLFDWLKEQNR--NSFVGWNT 608
BLAST of angiotensin converting enzyme-1 vs. UniProt/SwissProt
Match: sp|P12821|ACE_HUMAN (Angiotensin-converting enzyme OS=Homo sapiens OX=9606 GN=ACE PE=1 SV=1) HSP 1 Score: 335.109 bits (858), Expect = 1.424e-99 Identity = 191/591 (32.32%), Postives = 318/591 (53.81%), Query Frame = 3
Query: 135 YPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
YP + +DE A K+++ + N A N+ Y TNI + L++ + A + K +A+KF + ++ +KR ++ ++ R + L + I +E Y+ AT C G EP + + + Y+DL W WR+ G I + + + L NQ A +G+ D+ + + ++ + Q L F + Y LH YVR LH++Y N GPIPAH++G+ W+++W N++ ++ + + + T MFK ++ F++SLG+ + +FW +S+ +K + + CH + F NG DFRIK CT +L+DL HEMGHIQYFM Y++L V RE AN GF E GDV+ L+ TP +L + LLS+ + +IN+L+ ALD I FIPF+ ++++ V++GS+ N+ +W + K QG+ PPV RT+ FD GAK+H+ Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG +R W + M+++TG ++++ ++L+++ PL +WL+ +N+ K GW
Sbjct: 636 YPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGD-SWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQG---WTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGS-DEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221 HSP 2 Score: 310.842 bits (795), Expect = 8.067e-91 Identity = 166/486 (34.16%), Postives = 270/486 (55.56%), Query Frame = 3
Query: 465 IENIYNTATPCFKGCQPPG---EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+ IY+TA C +P + I + Y L W W NA G ++ L+ + L N+ GF D+ + + + F L + + + Y LH +VR LH+ Y +R+ N GPIPAH++G W++SW N++ ++ K + ++ L++ G H MF+++E F++SL + M +FW+ S+ +K + + CH + F N DFRIK CT + L+++ HEMGHIQY++ Y++L V R AN GF E GDV+ L+ TP +L KIGLL + N S+INYLL AL+ I F+PF ++++ V++G + N +W + K QGI PPV R E +FDAGAK+HV Y R+ S++ Q+ EA+C +GY+GPLHQC + S + GAK ++++ G++R W++ +K + G +L++ LL ++ P+ +WL+++N++ GW
Sbjct: 147 MSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY-WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQ------GWNATH-MFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLD-RVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623
BLAST of angiotensin converting enzyme-1 vs. UniProt/SwissProt
Match: sp|Q9GLN7|ACE_PANTR (Angiotensin-converting enzyme OS=Pan troglodytes OX=9598 GN=ACE PE=3 SV=1) HSP 1 Score: 335.109 bits (858), Expect = 1.591e-99 Identity = 190/591 (32.15%), Postives = 318/591 (53.81%), Query Frame = 3
Query: 135 YPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
YP + +DE A K+++ + N A N+ Y TNI + L++ + A + K +A++F + ++ +KR ++ ++ R + L + I +E Y+ AT C G EP + + + Y+DL W WR+ G I + + + L NQ A +G+ D+ + + ++ + Q L F + Y LH YVR LH++Y N GPIPAH++G+ W+++W N++ ++ + + + T MFK ++ F++SLG+ + +FW +S+ +K + + CH + F NG DFRIK CT +L+DL HEMGHIQYFM Y++L V RE AN GF E GDV+ L+ TP +L + LLS+ + +IN+L+ ALD I FIPF+ ++++ V++GS+ N+ +W + K QG+ PPV RT+ FD GAK+H+ Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG +R W + M+++TG ++++ ++L+++ PL +WL+ +N+ K GW
Sbjct: 634 YPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARRFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHTNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGD-SWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQG---WTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGS-DEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1219 HSP 2 Score: 315.079 bits (806), Expect = 2.651e-92 Identity = 190/609 (31.20%), Postives = 318/609 (52.22%), Query Frame = 3
Query: 129 EPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQ-----------IENIYNTATPCFKGCQPPG---EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+P N +DE A+ + Q N + + ++ + TNI N R ++++A+LS + + + ++ W + L+ RI + TL ++ + IY+TA C +P + I + Y L W W NA G ++ L+ + L N+ GF D+ + + + F L + + + Y LH +VR LH+ Y +R+ N GPIPAH++G W++SW N++ ++ K + ++ L++ G H MF+++E F++SL + M +FW+ S+ +K + + CH + F N DFRIK CT + L+++ HEMGHIQY++ Y++L V R AN GF E GDV+ L+ TPA+L KIGLL N+ N S+INYLL AL+ I F+PF ++++ V++G N+ N +W + K QGI PPV R E +FDAGAK+HV Y R+ S++ Q+ EA+C +GY+GPLHQC + S + GAK ++++ G++R W++ +K + G +L++ LL ++ P+ +WL+++N++ GW
Sbjct: 29 DPGLQPGNFSADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARR----QEEAALLSQEFAEAWGQKAKELYEPVWQNFTDPQLR---RIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY-WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQ------GWNATH-MFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRGGANPGFHEAIGDVLALSVSTPAHLHKIGLLD-NVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPNSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYQSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 621
BLAST of angiotensin converting enzyme-1 vs. UniProt/SwissProt
Match: sp|P09470|ACE_MOUSE (Angiotensin-converting enzyme OS=Mus musculus OX=10090 GN=Ace PE=1 SV=3) HSP 1 Score: 332.413 bits (851), Expect = 1.317e-98 Identity = 189/591 (31.98%), Postives = 322/591 (54.48%), Query Frame = 3
Query: 135 YPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
YP + +DE A ++++ + N A N++Y TNI + L++ + + + K +AK F + F++ +KR ++ L+ R L + I +E Y+ + C+ G P EP + + + Y++L W +WR+ G I F + + N+ A +G+ D+ + + ++ N Q L + + Y LH YVR LH++Y + + N GPIPAH++G+ W+++W N++ ++ + + I + T +FK +++F++SLG+ + +FW +S+ +K + + CHP + F NG DFRIK CT +++DL HEMGHIQYFM Y++L V FRE AN GF E GD+M L+ TP +L + LLST + +IN+L+ ALD I FIPF+ I+++ V++GS+ N+ +W + K QG+ PPV R++ FD G+K+HV Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MKLG ++ W + MK++TG ++++ +++ ++ PL EWL +N+ GW
Sbjct: 641 YPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPLEPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGD-SWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPNIDATEAMIKQG---WTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYE-YDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1226 HSP 2 Score: 312.768 bits (800), Expect = 1.751e-91 Identity = 164/486 (33.74%), Postives = 274/486 (56.38%), Query Frame = 3
Query: 465 IENIYNTATPCFKGCQPPG---EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+ IY+T CF +P + I + Y L W W +A G ++ L+ + + N+ F D+ F + ++ +F + L + + + Y LH YVR LH+ Y +++ N GPIPAH++G W++SW N++ ++ K + ++ ++K G H MF++SE F++SLG+ M +FW S+ +K + + CH + F N DFRIK CT ++ L ++ HEMGH+QY++ Y++L V R AN GF E GDV+ L+ TPA+L KIGLL N++ S+INYLL AL+ I F+PF ++++ V++G + N +W + K QGI PPV R E +FDAGAK+H+ Y R+ S++ Q+ +A+C +G++GPLHQC + S + GAK ++++ G +R W++ +K L G+ +L++ +LL ++ P+ +WL+++N+ GW
Sbjct: 152 MSRIYSTGKVCFPNKTATCWSLDPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAF-WRSWYESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMVQK------GWNATH-MFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIE-SDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGW 628
BLAST of angiotensin converting enzyme-1 vs. UniProt/SwissProt
Match: sp|Q50JE5|ACE_MESAU (Angiotensin-converting enzyme OS=Mesocricetus auratus OX=10036 GN=Ace PE=2 SV=1) HSP 1 Score: 330.102 bits (845), Expect = 9.634e-98 Identity = 190/591 (32.15%), Postives = 324/591 (54.82%), Query Frame = 3
Query: 135 YPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCF-KGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNR-FNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKH-KIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
YP + +DE A ++++ + N A N++Y TNI + L++ KK A + K AKKF + F++ +KR ++ ++ R L + I +E Y+ A C+ G EP + + + Y++L W +WR+ G I LF + + L N+ A +G+ D + + ++ + Q L + + Y LH YVR LH++Y ++ N GPIPAH++G+ W+++W N++ ++ + + I + T +FK ++ F++SLG+ ++++FW +S+ +K + + CH + F NG DFRIK CT +++DL HEMGHIQYFM Y++L V FRE AN GF E GDV+ L+ TP +L + LLS+ + +IN+L+ ALD I FIPF+ I+++ V++GS+ N+ +W + K QG+ PPV R+++ FD G+K+HV Y R+ S++ Q+ EA+C +G+ GPLH+C + SKE G + MK+G ++ W + MK++TG ++++ +++ ++ PL EWL +N+ GW
Sbjct: 642 YPEGIDLVTDETEAERFVEEYDRTARVLWNEYAEANWQYNTNITLEASKILLQKNKKVANHTLKYGTLAKKFDVSNFQNYTIKRIIKKVQNMDRAVLPPKELEEYNQILMDMETTYSIANVCYLNGTCLHLEPDLTNVMATSRKYEELLWVWKSWRDKVGRAILPLFPKYVELSNKIAHLNGYADGGD-SWRSSYESKSLEQDLEQLYQELQPLYLNLHAYVRRSLHRHYGSQHINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPNLDATEAMIKQG---WTPRRIFKEADDFFTSLGLLPVSEEFWNKSMLEKPGDGREVVCHASAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGGYEH-DINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQDDFDPGSKFHVPANVPYIRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADTMKMGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1227 HSP 2 Score: 314.309 bits (804), Expect = 5.005e-92 Identity = 158/464 (34.05%), Postives = 266/464 (57.33%), Query Frame = 3
Query: 522 EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
EP + I + Y L W +W + G ++ L+ + L N+ GF D+ + + + +F + L + + + Y LH YVR LH+ Y +++ N GPIPAH++G W++SW N++ ++ K + ++ ++K V MF+++E F++S+G+ M +FW S+ +K + + CH + F N DFRIK CT ++ L+++ HEMGH+QY++ Y++L+V R AN GF E GDV+ L+ TPA+L KIGLL N+L S+INYLL AL+ I F+PF ++++ V++G + N +W K QGI PPV R E +FDAGAK+H+ G Y R+ S++ Q+ +A+C +G++GPLHQC + S + GAK +++ G +R W++ +K + G+ +L++ +LL ++ P+ WL+++N+ GW
Sbjct: 175 EPELTNILASSRSYAKLLFAWESWHDVVGIPLKPLYQDFTALSNEAYKQDGFSDTGAY-WRSAYDSPSFEETLEHLYHQLEPLYLNLHAYVRRALHRRYGDKYINLRGPIPAHLLGDMWAQSWDNIYDMVVPFPNKPNLDVTNTMVQK-------GWNVTHMFRVAEEFFTSMGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFFNRKDFRIKQCTRITMEQLSTVHHEMGHVQYYLQYKDLTVPLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDRVANDLE-SDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGHTPPSRYNFDWWYFRTKYQGICPPVVRNETHFDAGAKFHIPSGTPYIRYFVSFILQFQFHQALCKEAGHQGPLHQCDIYQSTQAGAKLQRVLQAGYSRPWQEVLKEMVGSDTLDAQALLEYFQPVIRWLQEQNQRNGEVLGW 629
BLAST of angiotensin converting enzyme-1 vs. UniProt/SwissProt
Match: sp|Q6Q4G4|ACE_THETS (Angiotensin-converting enzyme OS=Theromyzon tessulatum OX=13286 GN=ACE PE=2 SV=1) HSP 1 Score: 315.079 bits (806), Expect = 2.441e-97 Identity = 184/575 (32.00%), Postives = 310/575 (53.91%), Query Frame = 3
Query: 165 ENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILS-WKMHXXXXXXXXXXXXSPWVKRSL-EMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPG-----EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPN-RFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKK 1865
E+ A+KWL N+ + + Y TN+ +NL IK A + K KKF K F P +KR ++ I + ++ + + IY+TA C K P G +P + +I ++ D ++L W WR+A+G + + + E + L N+ A +G+ D+ ++ + ++ F + + + I FY++LH YVR L K YP F K G IPAH++G+ W++SW N+ +L+ ++ D+ +E+ + T ++F+LS++F+ SLG+ M FW++S+ +K + + CH + F N DFRIK CTV D+ + HEMGHI+Y++ Y++ + FR AN GF E D+ L+ TP Y++ + LL N + N ++N+L+ AL + F+PF I+++ V++G + N +W K QG+ PPV R+E FDAG+K+HV Y R+ +++ Q+ EA+C + PLH+C+ NSKE G K E+MK G++ W K ++ LTG+ +++ SL+ +Y PL +W +K+
Sbjct: 30 ESDAKKWLTTYNDEAGKYIYDATEAEWNYNTNLTDHNLGISIKKSNDLATFTEQKAIEANKKFVWKNFTDPLLKREFSKITDIGTASLSDEDFQKMSGLNSDLTKIYSTAKVCNKPNDPSGKCYPLDPDLSDIISKSNDLEELTWAWKGWRDASGKHMPDKYDEFVQLLNKAANINGYEDNGDY-WRSWYESPTFRKDCEDLWQEIKPFYEQLHAYVRRKLQKKYPQIAFPKEGHIPAHLLGNMWAQSWENIEYLLRPA-PDLPSMDITEELVKQ--NYTALKLFQLSDTFFKSLGLIQMPQPFWEKSMIEKPADRDVVCHASAWDFYNRKDFRIKQCTVVDMHWFMTTHHEMGHIEYYLHYKDQPISFRSGANPGFHEAIADIASLSVATPEYMQSVSLLP-NFTDDPNGDLNFLMNQALTKVAFLPFGYLIDQWRWDVFSGDTPRPKYNSKWWHNRCKYQGVYPPVIRSEQDFDAGSKFHVPNNTPYIRYFVAHIIQFQFHEALCKAANNSRPLHRCNIANSKEAGKKLAELMKSGSSIPWPKVLENLTGSEKMSAKSLMAYYKPLIDWPEKR 599
BLAST of angiotensin converting enzyme-1 vs. TrEMBL
Match: I1ZIB1 (Angiotensin-converting enzyme (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1163.29 bits (3008), Expect = 0.000e+0 Identity = 585/591 (98.98%), Postives = 588/591 (99.49%), Query Frame = 3
Query: 123 ALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
ALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHLKAKKFRLKFFKSPWVKRSLEMLK SSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFS YKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHE DLRKEIDENIGKLTVHEMFKLSESFYSSLGM+NMTD+FWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEYVNSVYNGSVGNNEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELN+KTGW
Sbjct: 1 ALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHLKAKKFRLKFFKSPWVKRSLEMLKKSSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSLYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHEYDLRKEIDENIGKLTVHEMFKLSESFYSSLGMHNMTDEFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEYVNSVYNGSVGNNEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNVKTGW 591
BLAST of angiotensin converting enzyme-1 vs. TrEMBL
Match: A0A1S5QMZ5 (Angiotensin-converting enzyme OS=Tityus serrulatus OX=6887 PE=2 SV=1) HSP 1 Score: 360.918 bits (925), Expect = 1.858e-112 Identity = 201/595 (33.78%), Postives = 332/595 (55.80%), Query Frame = 3
Query: 144 VCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPCF-------KGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTG--TTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+ + DE A ++L N I+ N + + Y+TNI N ++L++ K A + F K FK P ++R + L I + + L+ +D + ++NIY+T+ C + C EP + EI + ++YD+LA W AWR+ +G R+++ +I + L N+ A +GF D+ E ++ F Q++ + I Y++LH YVR L Y ++ GPIPAHI+G+ W++ W + + + + K I +N+ L E+FK+SE F++S+G+ MTD+FW+RSI +K K + + CH + F +G DFRIK CT +++D HEMGHIQY+ Y + FRE AN GF E GD + L+ TP +L+ IGLL +I + ++N+L ++AL + F+PF I+ + +++G + + E+N +W++ K QGI PPVERTEN FD G+KYHV Y R+ S++ Q+ +++C +G+ GPLH+C + SK+ G +M++LG++ W + M I+TG T +++ + ++ PLY+WLK++NK I GW
Sbjct: 24 ISGDNRDEIAATQYLSAHNRILAEKCNIIVQAEWNYSTNITDENKQKLLEESSKYAEFQKEAWQNITSFAWKDFKDPLIRRWFKKLSILGKAALPNDQLKELDELIADMKNIYSTSKVCPFNSKETDENCNLSLEPELTEILTKSRNYDELAYIWKAWRDVSGKRVKDKYIRFIELSNKAAELNGFRDTGEL-WRERYESDTFQQEIEQLWQQIRPLYEQLHAYVRRKLINIYGSDKIRHDGPIPAHILGNMWAQDWSGILQDITPYPEKPSVDITPKMIAKNMSAL---EIFKISEEFFTSVGLKAMTDEFWERSIIEKPKDREIVCHASAWDFCDGKDFRIKQCTSINMEDFIVTHHEMGHIQYYQQYAHQPCVFREGANPGFHEAVGDCLALSTSTPKHLQTIGLLD-HIAEDKKGDVNFLFSTALSKLAFLPFGYLIDLWRWGIFSGDIKSTELNTKWWELRLKYQGICPPVERTENDFDPGSKYHVPGNTPYVRYFVSHVIQFQFHKSLCEAAGHVGPLHKCDIYKSKDAGKVLSQMLELGSSEIWNEAMNIMTGGVTNKMDAGPMFEYFEPLYQWLKEENKGEVI--GW 611
BLAST of angiotensin converting enzyme-1 vs. TrEMBL
Match: A0A2L2Y254 (Angiotensin-converting enzyme (Fragment) OS=Parasteatoda tepidariorum OX=114398 PE=2 SV=1) HSP 1 Score: 358.992 bits (920), Expect = 6.816e-112 Identity = 202/600 (33.67%), Postives = 333/600 (55.50%), Query Frame = 3
Query: 144 VCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILS---WKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPC------FKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPN-RFNKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILT--GTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
V ++D A ++LQ + + + N+ + Y +N+ +N +E ++M+++ A + WK K + + + S + L +I ++++Y A C C EP + EI +Y +L W WR+ TG +++N F+ + L N+ A +GF D+ E +F+ N +++ ++ I FY++LH YVR L K Y + GPIPAH++G+ W+++W N++ ++ KK ++ + L K K+ +MF++SE F++SLG+ MT FWK+SI +K + M CH + F N D RIKMCT D++DL ++ HEMGH++YF+ Y+ V FR ANSGF E GDV+ L+ TP +++KIGLL +N+ +EIN LL +ALD I F+PF I+ + V++GSV N++N +W++ K QG+ PPV RTE DA AKYHV Y R+ S++ Q+ +A+C+ +G+KGPLH+C + +K G + +KLG++ +WR+ MK++T T +++ ++L ++ PLY+WLK +NK N GW
Sbjct: 4 VSGDNTDLAAALRFLQDNDRLSEKITNKGVIAQWNYQSNLTEHNKKEFLRMEEEMAKFAKETWKNATSFAWKNFKGKNETAYRWFKALSVLGSAALPENKFNELGNINADMQDVYAKAKVCSYMSSLLDPCTLSIEPELTEIMKESTNYYELKHVWAQWRDETGKKMKNKFLRYVELSNEAACKNGFSDAGEM-WREEFETDNITEEFDQLWETIKPFYEQLHAYVRRKLIKEYTDIHIKPDGPIPAHLLGNMWAQTWGNIYRLVAPYPKKKAVDVTDTMLEK-------KMNARDMFEISEEFFTSLGLIPMTPTFWKKSIIEKPTDREMVCHASAWDFYNDGDVRIKMCTRIDMEDLITVHHEMGHVEYFLQYKVQPVVFRNGANSGFHEAIGDVLALSVATPDHMKKIGLLK-EVNHDPEAEINNLLKTALDKIAFVPFGFLIDAWRWRVFDGSVKTNQLNSAWWNLRLKYQGVCPPVLRTEKDLDAAAKYHVIADVPYIRYFVSFVIQFQFHKALCDEAGFKGPLHKCDIYQNKNAGKLLSDTLKLGSSVSWREAMKVITKGKTDKMDASAILEYFKPLYDWLKDQNK--NEYIGW 592
BLAST of angiotensin converting enzyme-1 vs. TrEMBL
Match: A0A1W7RA02 (Angiotensin-converting enzyme OS=Hadrurus spadix OX=141984 PE=3 SV=1) HSP 1 Score: 359.377 bits (921), Expect = 9.884e-112 Identity = 202/600 (33.67%), Postives = 340/600 (56.67%), Query Frame = 3
Query: 135 YPNVCNGHSD---ENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDI-RFQIENIYNTATPCF--KG------CQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+ N N H + EN A K+++ N + ++ + L+ ++ Y +N+ N ++I + +A H+K +F K F++P ++R ++L I R LR +++ + + NIY ++ C KG C EP +I+I +Y +L W WR+ G I+ ++ + L N+ A +GF D ++ F + + N + + Y+ LH YVR L + + ++ +GPIPAH++G+ W++ W N+ LK + +K + + K+T ++ KLSE F++SLG+ MT +FW +SI +K K + M CHP + F NG DFRIKMCT ++ L HEMGH+QY+M Y N FR+ AN GF E GDVM L+ TP +L+ IGLL + N ++N+L+++AL + F+PF ++++ V++G + ++ N +W + K QG+ PPV+RTE FD AKYH+ AY R+ S++ Q+ +A+C+++G+KGPLH+C +NSKE G + +M+++G++R W MK+LTG T +++ +L ++ PL +WLK+KN++ I GW
Sbjct: 27 FANCFNNHLEVRYENEAAKYIKEYNVLESKHCHDLSEASWNYTSNLTNANKAKMIAQQAINANFQKVAHIKLSRFPWKRFRNPQLRRQFKLLLILGRSALDPKKLRELNLCKADMANIYGSSKICLHVKGSKYDHKCNLALEPDLIDIMANSTNYKELLQVWKQWRDTVGPPIKKKYLRYVELSNEAARLNGFRDEGA-NWRKSYESVTFQRDIENLWRQVKPLYQHLHAYVRRRLIQLFGESKIRCNGPIPAHLLGNMWAQDWSNLIEYLKPFPTKPSFDVTQKMVAK---KMTPLDIVKLSEKFFTSLGLKAMTQEFWNKSIFEKPKDREMVCHPSAWDFCNGKDFRIKMCTEVNMDFLVITHHEMGHVQYYMQYANQPPTFRKGANEGFHEAIGDVMALSISTPKHLKTIGLLDNYTEDEEN-DLNFLMSTALKKVAFLPFGYIVDQWRWKVFSGKISPSQWNTEWWKLRLKYQGVCPPVKRTERDFDPAAKYHIPGDTAYIRYFVSFIIQFQFHQALCDIAGHKGPLHRCDIYNSKEAGKRLAQMLQMGSSRPWPVAMKVLTGKTKMDAGPILKYFEPLLKWLKEKNEDEII--GW 619
BLAST of angiotensin converting enzyme-1 vs. TrEMBL
Match: A0A1E1WWB8 (Angiotensin-converting enzyme OS=Tityus obscurus OX=1221240 PE=3 SV=1) HSP 1 Score: 356.681 bits (914), Expect = 5.427e-111 Identity = 209/586 (35.67%), Postives = 330/586 (56.31%), Query Frame = 3
Query: 162 DENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLK-ISSRIFDSSTTLRLIDIRFQIENIYNTATPC----FKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW*T 1901
+E+ A +++ VNE+ + N ++ Y TNI N ++I+ + ++ +S +M KF+ K F P ++R L + S + + + NIY+T T C K C EP + I DY +L W WRN G +IR L+ E ++L+N+ A +GF+D+ EF+ ++ Q L + I Y++LH YVR L + Y ++ K GPIPAH++G+ WS+ W N+ +I ++N D+ ++ +T ++ KL+E F+ SLG+ MT +FW S+ +K K + + CH + + DFRIKMC + L + HEMGH+QY+M Y N FR+ AN GF E GDVM L+ TP +L+ IGLL+ +++ R ++IN+LL AL I F+PF ++++ VY+G + E N+ +W++ K QG+ PP+ RTE FD GAK+HV Y R+ S++ Q+ EA+C +SG++GPLH+C +NSKE G MM++G++R W + + +TG+ +N+DSLL ++ PLYEWLK+ NK N GW T
Sbjct: 21 EEHFAFHFIRHVNEVNEKQCNLFQRASWNYDTNITIPNKNKMIEQQMIASNISKEMWKVLTKFQWKKFFDPQLRRQFYHLSFLGDSALPSDKIRKKTSLEADMTNIYSTTTICDFKNKKKCNLSLEPDLSSIMANSNDYYELLHVWKEWRNKVGRKIRPLYWEFVDLKNEAARLNGFNDAGEFQ-REKYESPTLIQDLEKLWHQIRPLYQQLHAYVRRKLIEMYGSDKIVKDGPIPAHLLGNMWSQEWQNIINITMP-YRNKPSLDVTPQMKAK--GMTPVQIAKLAEQFFVSLGLQPMTKEFWSNSLFEKPKDRKVVCHASAWDLCDKRDFRIKMCMECTMDFLITTHHEMGHVQYYMQYANQPHVFRKGANPGFHEAIGDVMSLSVYTPNHLQSIGLLNDIVSD-READINFLLQMALKKIAFLPFGYILDKWRWEVYSGEIEFEEWNRRWWEMRFKYQGVCPPIRRTEIDFDPGAKFHVPADTPYIRYFISFIIQFQFHEALCRVSGFQGPLHKCDIYNSKEAGKLISGMMQMGSSRPWPEAFEKITGSRKMNADSLLEYFKPLYEWLKEANK--NEVIGWET 599
BLAST of angiotensin converting enzyme-1 vs. Ensembl Cavefish
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:103040258]) HSP 1 Score: 337.806 bits (865), Expect = 1.610e-101 Identity = 199/595 (33.45%), Postives = 330/595 (55.46%), Query Frame = 3
Query: 129 EPYP-NVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLID-IRFQIENIYNTATPC-FKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCL-HKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGK-LTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
E YP +V + +DE A+++L N N ++ Y TNIN N + +++ + A + L+A+K+ F+ VKR L+ L R S L+ + + +E Y+ A C G P +P + +I +DYD+L W WRNA+G +R ++ + L N A +G D+ F + ++ F + L + ++ Y LH YVR L KY R N GPIPAH++G+ W+++W + +++ + N + D+ + + I K + MF+ SE+F++S+G+ M D+FW++S+ +K + + CH + F N DFRIK CTV ++ DL ++ HEMGH+QYF+ Y++ + FR+ AN GF E GDV+ L+ TP +L IGLL N S IN+L++ ALD I F+PF ++++ V++G + ++E NK +W++ K QG+ PPV RTE FD GAK+H+ Y R+ S++ Q+ +A+C+ +G+ GPLH C + SKE G ++MKLG ++ W + M ++TG ++ L+ ++ PL WL+++N + GW
Sbjct: 621 EGYPEDVADKITDEAQAKQFLAEYNSTAETVWNAYTEASWSYNTNINEANKQNMLEKNLEMANHTKTYGLEARKYDTSDFQDSSVKRILKKLSDLERAVLSDDDLKEYNNLLASMETTYSVAKVCKDDGTCLPLDPDLNKIMAESRDYDELLFAWQGWRNASGRELRQSYVRYVELANLAARSNGHADNGAFWRSL-YETPTFEEDLEALWKDLQPLYLNLHSYVRRALFKKYGAKRINLKGPIPAHLLGNMWAQTWSGIMDLVRP-YPNAAQVDVTQAM---IAKGWDANRMFRESENFFTSVGLLPMPDEFWQKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVINMDDLITVHHEMGHVQYFLQYKDQPISFRDGANPGFHEAIGDVLALSVSTPKHLHTIGLLDKLEENAE-STINFLMSIALDKIAFLPFGYLMDQWRWKVFDGRISSSEYNKEWWNLRLKYQGLCPPVTRTEVDFDPGAKFHIPANVPYVRYFVSFVVQFQFHKALCDTAGHTGPLHNCDIYQSKEAGKLLGDVMKLGFSKPWPEAMAMITGQPQMSVQPLMEYFQPLITWLEQENAKNGDVLGW 1209 HSP 2 Score: 317.39 bits (812), Expect = 3.558e-94 Identity = 163/484 (33.68%), Postives = 274/484 (56.61%), Query Frame = 3
Query: 453 IRFQIENIYNTATPCFKGCQPPG-EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKH-KIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
I Q++NIY+TA C K + EP + EI + Y L W W N +G +++L+ E + L N + GF D+ + + ++ F Q L N F + Y+ LH +VR L+ +Y P N GPIPAH++G+ WS++W+N+++++ + + +++N MF+++E F++SLG+ M KFW +S+ +K + + CH + F N DFRIK CT+ ++ L ++ HEMGH++Y++ Y++ V FR AN GF E GDV+ L+ TP +L IGLL T + N ++INYLL AL+ I F+PF I+++ V++G N +W + K QGI PPV RTE +FD GAKYH+ Y R+ S++ Q+ + +C +G+ GPLH C + S + GA ++++ G+++ W + ++ GT +++ +L+ ++ P+ WL+++N+ GW
Sbjct: 132 ILSQMDNIYSTAKVCPKPEECWALEPELKEILANSQSYKKLLYAWEGWHNVSGIPLKDLYPEFVQLSNNASVMDGFDDTGAY-WRSWYESPTFEQDLENLFKQLQPLYQNLHAFVRRKLYDFYGPKYINLKGPIPAHLLGNMWSQTWNNIYNMMIPFPDKPNVDVTNAMVEKN---YNATHMFRVAEEFFTSLGLKEMPQKFWDKSMLEKPDDGREVVCHASAWDFYNREDFRIKQCTIVTMEQLFTVHHEMGHVEYYLQYKDQPVSFRRGANPGFHEAVGDVLSLSVSTPKHLHTIGLLDT-LPNDNETDINYLLKMALEKIAFLPFGYLIDQWRWGVFSGRTPPERYNAEWWYLRTKYQGICPPVRRTEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHQKLCQEAGHTGPLHTCDIYRSTQAGAVLEKVLQAGSSKPWTEVLQEALGTNKMDAAALMEYFLPVTTWLEEQNRLTGETLGW 610
BLAST of angiotensin converting enzyme-1 vs. Ensembl Cavefish
Match: ace2 (angiotensin I converting enzyme 2 [Source:NCBI gene;Acc:103030208]) HSP 1 Score: 288.115 bits (736), Expect = 2.799e-86 Identity = 178/601 (29.62%), Postives = 305/601 (50.75%), Query Frame = 3
Query: 165 ENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTL------RLIDIRFQIENIYNTATPCFKG----CQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLAT---------DFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRS-ITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
E+ A+ +L + +E R + + ++ Y TNI N K+ ++ AI W + F + L +L++ S S L RL + ++ IY+T T C CQ EPG+ EI +DY + W WR G ++R L+ E +L+N+ A + + D ++ A + + +R+ + I YKELH YVR L YP +G +PAH++G W W N++ + K ++ + + DE +FK +E F+ S+ M M FW S +TK + CHP + N DFRIKMCT ++ D + HEMGH QY MAYR+L R+ AN GF E G++M L+ TP++L+ +GLL + ++IN+LL AL + +PF +EE+ V+ G++ ++ +W++ R+ G+ P+ R E+Y D A +HV+ +++ R+ ++Q+ + +A+C +G+ GPL++C NS + G K +M++LG +++W + ++ + G T +++ LL+++ LYEWLK++N++ N +GW
Sbjct: 21 EDRAKDFLLKFDEDASRLMYQYSLASWAYNTNITTENSN---KLAEQGAI--WSEYYSRVSEESNEFPIDQMSDELVILQLKSLQDKGSGALSPDKASRLSKVLNEMSTIYSTGTVCKIDNPFDCQT-LEPGLEEIMANSRDYYERLHVWEGWRVQVGKKMRKLYEEYADLKNEAAKLNNYKDYGDYWRANYETEDEPKYSYSRDELMRDVRSIYSEIMPLYKELHAYVRAKLQNTYPGHIASNGGLPAHLLGDMWGRFWTNLYPLAVPYPDKPDIDVSPAMVAQGWDE-------ERLFKEAEKFFVSVNMSAMFPNFWTNSMLTKPTDGTKVVCHPTAWDMGNREDFRIKMCTKVNMDDFLTAHHEMGHNQYQMAYRHLPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPADFTEDMETDINFLLKQALTIVATLPFTYMLEEWRWQVFQGTIPKDQWMLRWWEMKRELVGVTEPLPRDESYCDPPALFHVSGDYSFIRYFTRTVYQFQLQDALCKEAGHTGPLYKCDITNSTDAGNKLRDMLELGRSKSWTRALEQVCGDTRMDARPLLSYFSTLYEWLKEENQKNNRASGW 608
BLAST of angiotensin converting enzyme-1 vs. Ensembl Sea Lamprey
Match: ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:ZFIN;Acc:ZDB-GENE-030131-1826]) HSP 1 Score: 347.821 bits (891), Expect = 8.781e-106 Identity = 184/510 (36.08%), Postives = 300/510 (58.82%), Query Frame = 3
Query: 378 VKRSLEML-KISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHD-SAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNR-FNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
V+R L+ + +I + + +I ++E Y+ A C P +P I I ++YD+L YW WR+A+G ++R ++ + L N+ A +GF D A+++ A D + F L ++ + Y LH YVR LH++Y + N GPIPAH++G+ W++SW+N+ S++ N D + K T MF +S+ F++SLGM M +FW +S+ +K + + CH + F N DFRIK CTV + DL ++ HEMGH+QYF+ Y+ V FR+ AN GF E GDVM L+ TP +L++IGLL T +N S+IN+LL+ ALD I F+PF ++++ V++G + + NK +W++ K QG+ PPV RTE+ FD G+K+H+ Y R+ S++ Q+ EA+C +G KG LH+C + SK+ G K ++M+LG++R W++ M+++TG ++++ +LL ++ PL +WL K+N++ GW
Sbjct: 722 VRRQLKKISQIGTAALPETELKEYNEIVSRMETAYSVAKVCRGETCIPLDPDITAIMAESRNYDELLYYWQGWRDASGRKMREDYVRYVELSNKAAIANGFPDNGAQWRSAYDTE--TFEADLERIYEELKPLYLNLHAYVRRKLHQHYGDEHVNLKGPIPAHLLGNMWAQSWNNLNSLVAP-FPNAPSVDATPAMQAQ--KWTPKMMFNVSDVFFTSLGMIPMPREFWDKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVVTMDDLVTVHHEMGHVQYFLQYKEQPVPFRDGANPGFHEAIGDVMALSVATPKHLKEIGLLETVEDN-SESDINFLLSMALDKIAFLPFGFLMDQWRWKVFDGRIPTEDYNKEWWNLRMKYQGLCPPVARTEDDFDPGSKFHIPASVPYDRYFVSFVIQFQFQEALCAAAGQKGDLHKCDIYKSKDAGDKLAKVMQLGSSRRWQEAMEMITGQQNMSAAALLKYFKPLTDWLVKENQKNGEVLGW 1225 HSP 2 Score: 295.434 bits (755), Expect = 5.432e-87 Identity = 181/589 (30.73%), Postives = 298/589 (50.59%), Query Frame = 3
Query: 162 DENCARKWLQRVNEIM--IRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKI-SSRIFDSSTTLRLIDIRFQIENIYNTATPCFKG------CQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
DE A ++L N+ + + LA+ N+ NL+ +K++ +W K + + KR LE + I S D + + ++ IY+T C G C P +P I +I + Y L YW W N G + + + + L N + F D+ E+ + ++ F L ++ + Y LH YVR LH++Y +F N GPIPAH++G+ WS+ W+N+F ++ + D+ + E T MF+ SE F+ LG+ M +FW S+ +K + + CH + F N DFRIK CT+ ++ L ++ HEMGHI+Y++ Y++ V FR AN GF E GDV+ L+ TP +L+ IGLL + + S+INYL+ AL+ I F+PF I+ + V++G N+ +W + K QGI P V R FDAGAK+H+ Y R+ S++ Q+ +A+C + KGPL++C ++ G + M++G++R W + MK +TGT +++ L+ ++ P+ +WL+K+N +N GW
Sbjct: 47 DETGAEQFLADYNDTAEGVLYESVLASWNYNTNITEENQNLQVAASLKEQEFTEAWGQKAKDLFGNISHGFNETNKRLLEQISILGSANLDITEREEYNRLLSDMDAIYSTGKVCKPGQTSGTDCAPL-DPTITDILATSRSYKKLLYYWEGWHNVVGRPLHSKYARFVELSNAASQLDDFADTGEY-WRSWYESATFRDDLERIYEELKPLYLNLHAYVRRKLHQHYGEKFVNLKGPIPAHLLGNMWSQQWNNIFDMVVP-YPGKTSVDVTDTMVEQGWNAT--HMFRTSEDFFKDLGLLEMPPEFWSGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTIPTMEQLFTVHHEMGHIEYYLQYKDQHVSFRGGANPGFHEAIGDVLSLSVSTPTHLKTIGLLGPDYVGDKESDINYLMKMALEKIAFLPFGYLIDLWRWDVFSGKTPPERYNQDWWYLRTKYQGICPGVPRKSTDFDAGAKFHIPGNTPYIRYFVSFIIQFQFQKALCTAAQDKGPLYKCDIDKNQAAGNLLRKAMQMGSSRPWTEVMKEMTGTDKMSALPLIEYFKPVIDWLEKEN--VNETLGW 628
BLAST of angiotensin converting enzyme-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004373.1 (pep scaffold:Pmarinus_7.0:GL477858:25443:42821:1 gene:ENSPMAG00000003990.1 transcript:ENSPMAT00000004373.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 211.075 bits (536), Expect = 4.188e-62 Identity = 120/359 (33.43%), Postives = 180/359 (50.14%), Query Frame = 3
Query: 393 EMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQP-----PGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTN-INNLRNSEINYLLTSALDNIVFIPFAISIEE 1445
EM + S + L + Q++ Y+T C G P EP + I + Y L YW WR G +R + + L N+ + GF D+ EF + ++ F L +D + Y +H YVR LH+ Y R N GPIPAH++G W++ W ++ ++ + +++ G T H MF++SE F++SLG+ M +FW S+ +K + + CH + F N DFRIK CT + DL HEMGH+QYF+ Y+ V FR AN GF E GDVM L+ TP +L+KIGLL + + + S+IN+LL AL I F+PF +++
Sbjct: 28 EMRIMGSANLHPAAREELNRVILQMQTTYSTGAVCKPGHSSGPDCFPLEPELDHIMATSRSYTQLLYYWEGWRTDVGRPLRAPYAHFVQLSNEASRADGFADTGEFWRSV-YETETFRADLERLYDELRPLYLHMHAYVRRRLHRRYGERLVNLRGPIPAHLLGDMWAQQWQGIYDLVVPYPGKTRVDVTSAMVEQ--GWNTTH-MFRVSEEFFTSLGLMEMPPEFWNGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTSVTMTDLVRAHHEMGHVQYFLQYKEQPVPFRRGANPGFHEAIGDVMALSVATPRHLKKIGLLEPSYVEDPAESDINFLLWMALGKIAFLPFGFLVDQ 382
BLAST of angiotensin converting enzyme-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004370.1 (pep scaffold:Pmarinus_7.0:GL477858:22090:39821:1 gene:ENSPMAG00000003990.1 transcript:ENSPMAT00000004370.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 193.356 bits (490), Expect = 1.558e-55 Identity = 119/377 (31.56%), Postives = 183/377 (48.54%), Query Frame = 3
Query: 243 FKYATNINGNNLRELI--KMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSL-EMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQP-----PGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKK-LKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLL 1343
+ ++TN+ NL L+ ++K + +W K ++ ++R L EM + S + L + Q++ Y+T C G P EP + I + Y L YW WR G +R + + L N+ + GF D+ EF + ++ F L +D + Y +H YVR LH+ Y R N GPIPAH++G W++ W ++ ++ + +++ G T H MF++SE F++SLG+ M +FW S+ +K + + CH + F N DFRIK CT + DL HEMGH+QYF+ Y+ V FR AN GF E GDVM L+ TP +L+KIGLL
Sbjct: 31 WGHSTNMTAVNLERLVEARLKMQEFTEAWGEKTKYLYDDIRDGFPDDLRRLLREMRIMGSANLHPAAREELNRVILQMQTTYSTGAVCKPGHSSGPDCFPLEPELDHIMATSRSYTQLLYYWEGWRTDVGRPLRAPYAHFVQLSNEASRADGFADTGEFWRSV-YETETFRADLERLYDELRPLYLHMHAYVRRRLHRRYGERLVNLRGPIPAHLLGDMWAQQWQGIYDLVVPYPGKTRVDVTSAMVEQ--GWNTTH-MFRVSEEFFTSLGLMEMPPEFWNGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTSVTMTDLVRAHHEMGHVQYFLQYKEQPVPFRRGANPGFHEAIGDVMALSVATPRHLKKIGLL 403
BLAST of angiotensin converting enzyme-1 vs. Ensembl Nematostella
Match: EDO37947 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEG1]) HSP 1 Score: 305.834 bits (782), Expect = 4.831e-95 Identity = 164/511 (32.09%), Postives = 274/511 (53.62%), Query Frame = 3
Query: 378 VKRSLEMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGE-----PGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
KR ++++ S+ + + R ++ Q++ IY++ K GE P + +I +DY+ L W WR+A G IR L+ + +++ N+ A ++G+ D+ E+ + ++ N + + ++ Y+ELH YVR+ L + Y ++ IPAH+ G+ W++SW N++ +++ + R + + +L M +L+ESF++S+G+ + F+ RS+ K K + + CH + F D RIK CT L + HE+GHIQYF+ Y + +R AN GF E GD + L+ TPA+L +IGLL NN S+IN L+ AL + F+PF I+++ V+ G + N+ +W++ K QGI PPV RTEN FD GAKYH+ Y R+ SY+ Q+ +A C +G+ GPLH+C +NS G K M+KLG ++ W + +K +TGT ++ L ++ PL W+K + + GW
Sbjct: 96 TKRQIKLIAASASPKNPADIKRKSELNSQMDKIYSSG----KVKDANGEMLSLNPDLYKILAESRDYERLLFVWKGWRDAVGPAIRPLYQQFVDISNKGAKENGWKDNGEY-WRSSYEVENLERIAEGLYSDLKPLYQELHAYVRYKLSQQY-SQVKSGDAIPAHLFGNMWAQSWANIYDLVEPYGNQSSLDVTRNMVKQGYTEL---RMVQLAESFFTSIGLDPLPQSFYNRSMIVKPKDRGVVCHASAWDFLISRDVRIKQCTTITHDSLVTTHHELGHIQYFLQYAHQPYEYRTGANPGFHEAVGDTLSLSVDTPAHLHRIGLLDAVSNNTE-SDINALMKMALSKVAFLPFGFLIDQWRWRVFRGEITPQNYNRKWWELRTKYQGIKPPVCRTENDFDPGAKYHIPANTPYIRYFVSYVIQFQFHKAACEAAGHTGPLHKCSIYNSTAAGGKLGAMLKLGKSKPWPQALKAMTGTEEMDVGPLTEYFKPLITWMKAQRAKHGYPIGW 596
BLAST of angiotensin converting enzyme-1 vs. Ensembl Nematostella
Match: EDO35659 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKY7]) HSP 1 Score: 312.383 bits (799), Expect = 1.188e-93 Identity = 163/507 (32.15%), Postives = 286/507 (56.41%), Query Frame = 3
Query: 378 VKRSLEMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPC-FKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+R ++M+ ++ D L D+ +++ IY + G + +P + +I + +DY+ L W WR+ATG +R L+ + + L N+ A ++G+ D+ E+ + ++ N + ++++ Y+ELH YVR+ L K Y ++ +GPIPAH+ G+ W++SW N++ I++ + + + +N +L M +L+ESF++S+G+ + F+++S+ K + + + CH + F+ D RIK CT L + HE+GHIQY++ Y + +R AN GF E GD + L+ TP +L+ IGLL ++N S+IN L+ AL + F+PF I+++ V++G + ++ N+ +W + K QGI PPV RTEN FD GAKYH+ Y R+ S++ Q+ +A C +G++GPLH+C +NS E G K +M+ LG ++ W ++ +TGT ++ SL ++ PL +WLK + +E GW
Sbjct: 563 TRRQIKMVTETASSSDKDVQKTLNDVEGKMDQIYGSGKVIDTDGSKLSLDPHLYKILSNSRDYERLKFVWKGWRDATGPELRPLYKQFVELANKGAKENGWADNGEW-WRSWYEIDNLESSVEALYEDLRPLYEELHAYVRYKLSKKY-SQVKPTGPIPAHVFGNMWAQSWVNIYDIIEPYENQPSLDVTKTMVAQNYTQL---RMVQLAESFFTSIGLKALPMSFYEKSMIVKPEGREVQCHASAWDFKINRDVRIKQCTTITHNYLVTTHHELGHIQYYLQYWDQPFEYRTGANPGFHEAVGDTLSLSVDTPTHLKLIGLLDA-VSNDSKSDINALMKMALRKVAFLPFGFLIDQWRWKVFSGDITSDNYNREWWKLRTKYQGIKPPVCRTENDFDPGAKYHIPGNTPYIRYFVSFVLQFQFHKAACEAAGHQGPLHKCSIYNSTEAGKKLGDMLSLGKSKPWPLALEQMTGTRKMDVSSLKEYFKPLSDWLKSQRQEYKYTIGW 1063 HSP 2 Score: 280.026 bits (715), Expect = 5.447e-82 Identity = 148/462 (32.03%), Postives = 260/462 (56.28%), Query Frame = 3
Query: 525 PGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYS-DSFENGV----DFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
P + E+ ++ +L W WR TG ++R LF + + L NQ A D+GF + E++ ++ N + + + + Y ELH YVR L + YP+ + S IPAH++G+ W+++W N++ +++ + D+ K + + T +M +L+E+F+ S+G + F+ +S+ +K + + + CH + D FE D RIK CT +DL HEMGHI YF+ Y + +R+ AN F E GD + L+ TP +L K+ LL + + + +EIN L+ AL I F+PF +E++ VY G + ++E NK +W++ K+QG+ PP+ R E FD G+K+H+A Y ++ S + Q+ + + +C+++G PLH+C +NS + G K M+++G ++ WR T++ TG+ ++ + L ++HPLY+WL ++ + K GW
Sbjct: 32 PQLTELMANSRNSPELLAAWRDWRQVTGPKMRPLFKDCVTLANQGAKDNGFQNMYEYQTHL-YELPNLEEYIDGIWQELKVLYLELHAYVRQRLSEQYPHVLS-SQAIPAHLLGNMWAQNWVNIYPLVEP-YSGKPSLDVTKNLRQQ--NYTAVKMVQLAEAFFRSIGFEKLPGSFYSKSMFEKPEDREVLCHAAALDFFEKNSKGEKDVRIKQCTEITHQDLIITHHEMGHIYYFLKYWDQPYIYRDGANPAFHEALGDTIALSVDTPRHLVKVKLLDEYMED-KEAEINALMKMALSKIAFLPFGYLLEKWRWQVYTGEIDSSEYNKKWWELRVKHQGVRPPISRDETTFDPGSKFHIAANARYIQYFLSRILQFQLHKTVCDIAGINEPLHKCSIYNSTKAGQKLSAMLEMGRSKPWRDTLEAFTGSRDMSVNPLKEYFHPLYQWLVEQRCQNKYKIGW 487
BLAST of angiotensin converting enzyme-1 vs. Ensembl Nematostella
Match: EDO34063 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQE7]) HSP 1 Score: 291.582 bits (745), Expect = 1.857e-91 Identity = 153/458 (33.41%), Postives = 252/458 (55.02%), Query Frame = 3
Query: 522 EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+P + + +R ++ D+L W WR+A +R +F + ++L N+ A G D F+ +F+ ++ + ++ YKELH YVR L K Y + SGPIPAH++G+ W+++W ++ +++ + + D+ + + T +MFKL++SF+ S+G+ M FW +S+ +K +K + CH + F D RIKMCT +DL +I HEMGH +YF+AY++ +R AN GF E GD + L+ TP +L +GLL T + + IN+L+T AL ++ +PF ++++ V G + + N +W + QG+ PPV R E+ FD GAK+H+ Y + S + Q+ A+CNL + GPLH+C + SKE G K EM+ G +R W +T+ LTG +++D LL ++ PL +WL + N GW
Sbjct: 28 DPDLGNLMSRSRNQDELVWAWRGWRDAVAPPVRGMFQQMVDLLNKGARQHGLGDYGHFERGEYEMGNDFTAVIKKLWTDVKPLYKELHAYVRFQLKKKYAG-MSGSGPIPAHLLGNMWAQNWDGIYDMVQP-YPDATPLDVTPSLIKQ--HYTPEKMFKLAQSFFVSIGLDPMPKSFWNKSMLRKPGNKSVVCHASAFDFLKD-DVRIKMCTRLKQEDLITIHHEMGHCEYFLAYKDQPYAYRNGANPGFHEAIGDTIALSVVTPKHLNSVGLLYT-LPKGDEASINFLMTQALSHVAPLPFTYLVDQWRWKVLAGEISPSNYNSAWWRMRTLYQGVKPPVARNESDFDPGAKFHIVSNSPYIGYFVSLILQFQFHRALCNLVKHTGPLHECSIYQSKEAGKKFKEMLAAGRSRPWPQTLFKLTGEREMSADPLLEYFAPLRKWLFNYRIKNNYTLGW 479
BLAST of angiotensin converting enzyme-1 vs. Ensembl Nematostella
Match: EDO29688 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2Y1]) HSP 1 Score: 289.656 bits (740), Expect = 1.020e-90 Identity = 148/445 (33.26%), Postives = 247/445 (55.51%), Query Frame = 3
Query: 522 EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWL 1856
+P + + +R ++ D+L W WR+A +R +F + ++L N+ A G D F+ +F+ ++ + ++ YKELH YVR L K Y + SGPIPAH++G+ W+++W ++ +++ + + D+ + + T +MFKL++SF+ S+G+ M FW +S+ +K +K + CH + F IKMCT +DL +I HEMGH +YF+AY++ +R AN GF E GD + L+ TP +L +GLL T + + IN+L+T AL ++ +PF ++++ V G + + N +W + QG+ PPV R E+ FD GAK+H+ Y + S + Q+ A+CNL+ + GPLH+C + SKE G K EM+ G +R W +T+ LTG +++D LL ++ PL +WL
Sbjct: 28 DPDLGNLMSRSRNQDELVWAWRGWRDAVAPPVRGMFQQMVDLLNKGARQHGLGDYGHFERGEYEMGNDFTAVIKKLWTDVKPLYKELHAYVRFQLKKKYAG-MSGSGPIPAHLLGNMWAQNWDGIYDMVQP-YPDATPLDVTPSLIKQ--HYTPEKMFKLAQSFFVSIGLDPMPKSFWNKSMLRKPGNKSVVCHASAFDFSKMTSGAIKMCTRLKQEDLITIHHEMGHCEYFLAYKDQPYAYRNGANPGFHEAIGDTIALSVVTPKHLNSVGLLYT-LPKGDEASINFLMTQALSHVAPLPFTYLVDQWRWKVLAGEISPSNYNSAWWRMRTLYQGVKPPVARNESDFDPGAKFHIVSNSPYIGYFVSLILQFQFHRALCNLAKHTGPLHECSIYQSKEAGKKFKEMLAAGRSRVWPQTLFKLTGEREMSADPLLEYFAPLRKWL 467
BLAST of angiotensin converting enzyme-1 vs. Ensembl Nematostella
Match: EDO28297 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6V7]) HSP 1 Score: 194.512 bits (493), Expect = 1.165e-56 Identity = 113/353 (32.01%), Postives = 183/353 (51.84%), Query Frame = 3
Query: 837 SGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
SGPIPAH++G+ W+++W ++ +++ + + D+ + + T +MFKL++SF+ S+G+ M FW +S+ +K +K + CH + F D RIKMCT +DL +I HEMGH +YF+AY++ +R AN GF E GD + L+ TP +L +GLL T + + IN+L+T AL ++ +PF +D R + + R +D + + Y R+ S + Q+ A+CNL + GPLH+C + SKE G K EM+ G +R W +T+ LTG +++D LL ++ PL +WL + N GW
Sbjct: 4 SGPIPAHLLGNMWAQNWDGIYDMVQP-YPDATPLDVTPSLIKQ--HYTPEKMFKLAQSFFVSIGLDPMPKSFWNKSMLRKPGNKSVVCHASAFDFLKD-DVRIKMCTRLKQEDLITIHHEMGHCEYFLAYKDQPYAYRNGANPGFHEAIGDTIALSVVTPKHLNSVGLLYT-LPKGDEASINFLMTQALSHVAPLPFT------------------------FDFYRHDFIDITLFHR----YDFIDMTFIDMTLLY-RYFVSLILQFQFHRALCNLVKHTGPLHECSIYQSKEAGKKFKEMLAAGRSRPWPQTLFKLTGEREMSADPLLEYFAPLRKWLFNYRIKNNYTLGW 322
BLAST of angiotensin converting enzyme-1 vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772]) HSP 1 Score: 329.331 bits (843), Expect = 6.034e-99 Identity = 192/595 (32.27%), Postives = 319/595 (53.61%), Query Frame = 3
Query: 129 EPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQ-IENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNV--FSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKH-KIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
E YP ++DE A++ L N N ++KY T+I N + ++ + + + K LKA+++ F+ P VKR + L R L + +E Y+ A C + G P +P + +I +DY++L W WR+A G +R + + L N+ A G+ D+ + ++ F + L + + + Y+ +H YVR L+K Y P N GPIPAH++G+ W+++W + F+I + N + MF+ S+ F++SLG+ M ++FW++S+ +K + + CH + F N DFRIK CTV + DL ++ HEMGH+QYF+ Y++ V FR+ AN GF E GDV+ L+ TP +L+ IGLL N S+IN+L++ ALD I F+PF ++++ V++G + NE NK +W++ K QG+ PPV RTE FD GAK+H+ Y R+ S++ Q+ +A+C + + GPLH C + SKE G ++MKLG+++ W + M I+TG + +++ L+ ++ PL +WL+++N+ GW
Sbjct: 545 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYNTLLSNMETKYSVAEVCREDGRCHPLDPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGAMWRSL-YETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIPYPGATQVDATPAMLAQGWNATR-----MFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYE-SDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1132 HSP 2 Score: 297.745 bits (761), Expect = 1.800e-87 Identity = 157/464 (33.84%), Postives = 266/464 (57.33%), Query Frame = 3
Query: 522 EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDS-AEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
EP + +I + Y L W W NA+G ++ L+ E + L N+ + GF D+ A+++ + ++ F Q + N + I Y LH +VR L+ Y +++ N GPIPAH++G+ W+++W+N++ ++ K + ++ + +R+ G H MF++SE F++SLG+ M +FW+ S+ K + + CH + F N DFRIK CT ++ L ++ HEMGHIQY++ Y++ V FR AN GF E GDV+ L+ TP +L I LL + ++ ++INYLL AL+ I F+PF I+ + V+NG + N +W + K QGI PP +R+E +FD GAKYH+ Y R+ S++ Q+ E +C + + GPLH C + S E G ++++ G+++ W + ++ GT +N++SLL ++ P+ +WL+++N +N GW
Sbjct: 83 EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGADWR--SWYESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIPFPNKPNLDVTDEMVRQ------GYNATH-MFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASD-TETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 534
BLAST of angiotensin converting enzyme-1 vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772]) HSP 1 Score: 329.331 bits (843), Expect = 6.034e-99 Identity = 192/595 (32.27%), Postives = 319/595 (53.61%), Query Frame = 3
Query: 129 EPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQ-IENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNV--FSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKH-KIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
E YP ++DE A++ L N N ++KY T+I N + ++ + + + K LKA+++ F+ P VKR + L R L + +E Y+ A C + G P +P + +I +DY++L W WR+A G +R + + L N+ A G+ D+ + ++ F + L + + + Y+ +H YVR L+K Y P N GPIPAH++G+ W+++W + F+I + N + MF+ S+ F++SLG+ M ++FW++S+ +K + + CH + F N DFRIK CTV + DL ++ HEMGH+QYF+ Y++ V FR+ AN GF E GDV+ L+ TP +L+ IGLL N S+IN+L++ ALD I F+PF ++++ V++G + NE NK +W++ K QG+ PPV RTE FD GAK+H+ Y R+ S++ Q+ +A+C + + GPLH C + SKE G ++MKLG+++ W + M I+TG + +++ L+ ++ PL +WL+++N+ GW
Sbjct: 545 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYNTLLSNMETKYSVAEVCREDGRCHPLDPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGAMWRSL-YETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIPYPGATQVDATPAMLAQGWNATR-----MFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYE-SDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1132 HSP 2 Score: 297.745 bits (761), Expect = 1.800e-87 Identity = 157/464 (33.84%), Postives = 266/464 (57.33%), Query Frame = 3
Query: 522 EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDS-AEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
EP + +I + Y L W W NA+G ++ L+ E + L N+ + GF D+ A+++ + ++ F Q + N + I Y LH +VR L+ Y +++ N GPIPAH++G+ W+++W+N++ ++ K + ++ + +R+ G H MF++SE F++SLG+ M +FW+ S+ K + + CH + F N DFRIK CT ++ L ++ HEMGHIQY++ Y++ V FR AN GF E GDV+ L+ TP +L I LL + ++ ++INYLL AL+ I F+PF I+ + V+NG + N +W + K QGI PP +R+E +FD GAKYH+ Y R+ S++ Q+ E +C + + GPLH C + S E G ++++ G+++ W + ++ GT +N++SLL ++ P+ +WL+++N +N GW
Sbjct: 83 EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGADWR--SWYESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIPFPNKPNLDVTDEMVRQ------GYNATH-MFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASD-TETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 534
BLAST of angiotensin converting enzyme-1 vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772]) HSP 1 Score: 329.717 bits (844), Expect = 1.153e-98 Identity = 192/595 (32.27%), Postives = 319/595 (53.61%), Query Frame = 3
Query: 129 EPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQ-IENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNV--FSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKH-KIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
E YP ++DE A++ L N N ++KY T+I N + ++ + + + K LKA+++ F+ P VKR + L R L + +E Y+ A C + G P +P + +I +DY++L W WR+A G +R + + L N+ A G+ D+ + ++ F + L + + + Y+ +H YVR L+K Y P N GPIPAH++G+ W+++W + F+I + N + MF+ S+ F++SLG+ M ++FW++S+ +K + + CH + F N DFRIK CTV + DL ++ HEMGH+QYF+ Y++ V FR+ AN GF E GDV+ L+ TP +L+ IGLL N S+IN+L++ ALD I F+PF ++++ V++G + NE NK +W++ K QG+ PPV RTE FD GAK+H+ Y R+ S++ Q+ +A+C + + GPLH C + SKE G ++MKLG+++ W + M I+TG + +++ L+ ++ PL +WL+++N+ GW
Sbjct: 623 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYNTLLSNMETKYSVAEVCREDGRCHPLDPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGAMWRSL-YETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIPYPGATQVDATPAMLAQGWNATR-----MFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYE-SDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1210 HSP 2 Score: 298.13 bits (762), Expect = 2.554e-87 Identity = 157/464 (33.84%), Postives = 266/464 (57.33%), Query Frame = 3
Query: 522 EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDS-AEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
EP + +I + Y L W W NA+G ++ L+ E + L N+ + GF D+ A+++ + ++ F Q + N + I Y LH +VR L+ Y +++ N GPIPAH++G+ W+++W+N++ ++ K + ++ + +R+ G H MF++SE F++SLG+ M +FW+ S+ K + + CH + F N DFRIK CT ++ L ++ HEMGHIQY++ Y++ V FR AN GF E GDV+ L+ TP +L I LL + ++ ++INYLL AL+ I F+PF I+ + V+NG + N +W + K QGI PP +R+E +FD GAKYH+ Y R+ S++ Q+ E +C + + GPLH C + S E G ++++ G+++ W + ++ GT +N++SLL ++ P+ +WL+++N +N GW
Sbjct: 161 EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGADWR--SWYESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIPFPNKPNLDVTDEMVRQ------GYNATH-MFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASD-TETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 612
BLAST of angiotensin converting enzyme-1 vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772]) HSP 1 Score: 329.717 bits (844), Expect = 1.237e-98 Identity = 192/595 (32.27%), Postives = 319/595 (53.61%), Query Frame = 3
Query: 129 EPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQ-IENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNV--FSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKH-KIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
E YP ++DE A++ L N N ++KY T+I N + ++ + + + K LKA+++ F+ P VKR + L R L + +E Y+ A C + G P +P + +I +DY++L W WR+A G +R + + L N+ A G+ D+ + ++ F + L + + + Y+ +H YVR L+K Y P N GPIPAH++G+ W+++W + F+I + N + MF+ S+ F++SLG+ M ++FW++S+ +K + + CH + F N DFRIK CTV + DL ++ HEMGH+QYF+ Y++ V FR+ AN GF E GDV+ L+ TP +L+ IGLL N S+IN+L++ ALD I F+PF ++++ V++G + NE NK +W++ K QG+ PPV RTE FD GAK+H+ Y R+ S++ Q+ +A+C + + GPLH C + SKE G ++MKLG+++ W + M I+TG + +++ L+ ++ PL +WL+++N+ GW
Sbjct: 625 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYNTLLSNMETKYSVAEVCREDGRCHPLDPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGAMWRSL-YETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIPYPGATQVDATPAMLAQGWNATR-----MFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYE-SDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1212 HSP 2 Score: 298.13 bits (762), Expect = 2.916e-87 Identity = 157/464 (33.84%), Postives = 266/464 (57.33%), Query Frame = 3
Query: 522 EPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDS-AEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
EP + +I + Y L W W NA+G ++ L+ E + L N+ + GF D+ A+++ + ++ F Q + N + I Y LH +VR L+ Y +++ N GPIPAH++G+ W+++W+N++ ++ K + ++ + +R+ G H MF++SE F++SLG+ M +FW+ S+ K + + CH + F N DFRIK CT ++ L ++ HEMGHIQY++ Y++ V FR AN GF E GDV+ L+ TP +L I LL + ++ ++INYLL AL+ I F+PF I+ + V+NG + N +W + K QGI PP +R+E +FD GAKYH+ Y R+ S++ Q+ E +C + + GPLH C + S E G ++++ G+++ W + ++ GT +N++SLL ++ P+ +WL+++N +N GW
Sbjct: 163 EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGADWR--SWYESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIPFPNKPNLDVTDEMVRQ------GYNATH-MFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTE-TDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 614
BLAST of angiotensin converting enzyme-1 vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772]) HSP 1 Score: 329.717 bits (844), Expect = 1.280e-98 Identity = 192/595 (32.27%), Postives = 319/595 (53.61%), Query Frame = 3
Query: 129 EPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQ-IENIYNTATPCFK-GCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYY-PNRFNKSGPIPAHIVGSPWSESWHNV--FSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKH-KIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
E YP ++DE A++ L N N ++KY T+I N + ++ + + + K LKA+++ F+ P VKR + L R L + +E Y+ A C + G P +P + +I +DY++L W WR+A G +R + + L N+ A G+ D+ + ++ F + L + + + Y+ +H YVR L+K Y P N GPIPAH++G+ W+++W + F+I + N + MF+ S+ F++SLG+ M ++FW++S+ +K + + CH + F N DFRIK CTV + DL ++ HEMGH+QYF+ Y++ V FR+ AN GF E GDV+ L+ TP +L+ IGLL N S+IN+L++ ALD I F+PF ++++ V++G + NE NK +W++ K QG+ PPV RTE FD GAK+H+ Y R+ S++ Q+ +A+C + + GPLH C + SKE G ++MKLG+++ W + M I+TG + +++ L+ ++ PL +WL+++N+ GW
Sbjct: 649 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYNTLLSNMETKYSVAEVCREDGRCHPLDPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGAMWRSL-YETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIPYPGATQVDATPAMLAQGWNATR-----MFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYE-SDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1236 HSP 2 Score: 285.034 bits (728), Expect = 1.098e-82 Identity = 151/459 (32.90%), Postives = 259/459 (56.43%), Query Frame = 3
Query: 537 EIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDS-AEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRF-NKSGPIPAHIVGSPWSESWHNVFSIL----KKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
EI + + Y+ L W AWRN +G ++ L+ + L N+ + GF D+ A+++ + ++ F Q + + + Y LH +VR L+ Y +++ N GPIPAH++GS +++ W++++ ++ K + ++ + +R+ + V MF+++E F++SLG+ M +FW+ S+ K + + CH + F N DFRIK CT + D ++ HEMGHIQYF+ Y+N V FR AN GF E GDV+ L+ TP +L I LL + + +++N+LL ALD I F+P I+ + V++GS N +W + K QGI PP+ RTE FD GAK+H+ Y R+ S++ Q+ E +C + + GPLH C + S E G ++++ G+++ W + ++ GT +N++SLL ++ P+ +WL+++N +N GW
Sbjct: 192 EIMAKSRSYEKLLFVWEAWRNESGVPLKQLYTRFVELSNKASRADGFADTGADWR--SWYESETFEQDMDKLYKTLQPLYLHLHAFVRRKLYDLYGSKYINLKGPIPAHLLGSMFAQKWNHIYDLMIPFPDKPNLDVTDEMVRQGYN-------VTHMFRVAEEFFTSLGLMEMPKEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTKVTMDDFFTVHHEMGHIQYFLQYKNQPVGFRSGANPGFHEAIGDVIFLSVSTPKHLHTINLLGSGDAD-EETDLNHLLKMALDKIAFLPSGYLIDLWRWEVFSGSTPPERYNADWWYLRTKYQGICPPIRRTEEQFDPGAKFHIPNNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 638
BLAST of angiotensin converting enzyme-1 vs. Planmine SMEST
Match: SMESG000005713.1 (SMESG000005713.1) HSP 1 Score: 1236.09 bits (3197), Expect = 0.000e+0 Identity = 619/626 (98.88%), Postives = 622/626 (99.36%), Query Frame = 3
Query: 15 MLIKIVSQLFVLLLQFNEISNQLFRSRIFDSYGEKSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTG 1892
MLIKIVSQLFVLLLQFNEISNQLFRSRIFDSYGEKSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHLKAKKFRLKFFKSPWVKRSLEMLK SSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFS YKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHE DLRKEIDENIGKLTVHEMFKLSESFYSSLGM+NMTD+FWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEYVNSVYNGSVGNNE NKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELN+KTG
Sbjct: 1 MLIKIVSQLFVLLLQFNEISNQLFRSRIFDSYGEKSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHLKAKKFRLKFFKSPWVKRSLEMLKKSSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSLYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHEYDLRKEIDENIGKLTVHEMFKLSESFYSSLGMHNMTDEFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEYVNSVYNGSVGNNETNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNVKTG 626
BLAST of angiotensin converting enzyme-1 vs. Planmine SMEST
Match: SMESG000005713.1 (SMESG000005713.1) HSP 1 Score: 1233.01 bits (3189), Expect = 0.000e+0 Identity = 620/627 (98.88%), Postives = 623/627 (99.36%), Query Frame = 3
Query: 15 MLIKIVSQLFVLLLQFNEISNQLFRSRIFDSYGEKSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
MLIKIVSQLFVLLLQFNEISNQLFRSRIFDSYGEKSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHLKAKKFRLKFFKSPWVKRSLEMLK SSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFS YKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHE DLRKEIDENIGKLTVHEMFKLSESFYSSLGM+NMTD+FWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEYVNSVYNGSVGNNE NKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELN+KTGW
Sbjct: 1 MLIKIVSQLFVLLLQFNEISNQLFRSRIFDSYGEKSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHLKAKKFRLKFFKSPWVKRSLEMLKKSSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSLYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHEYDLRKEIDENIGKLTVHEMFKLSESFYSSLGMHNMTDEFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEYVNSVYNGSVGNNETNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNVKTGW 627
BLAST of angiotensin converting enzyme-1 vs. Planmine SMEST
Match: SMESG000005698.1 (SMESG000005698.1) HSP 1 Score: 620.928 bits (1600), Expect = 0.000e+0 Identity = 302/608 (49.67%), Postives = 429/608 (70.56%), Query Frame = 3
Query: 72 SNQLFRSRIFDSYGEKSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
S+ +++ +IFDSY + LE YP VC +S+ENCA+ WL +VNEI IRN+NR AN+N++Y +NIN NL L K + L + LKAKKF+ K F SP V++ L+ L + R D + + L++++ +IE IYN PCF C P GEP II++F + KDYD L GYWVAWRN TG+RIRNLF++++ LEN A ++GF D A F L DF+E NF + + ++ I YKELH +VR+CL KYYP +F+K+GPIPAHI G+ WS+ W N+F I+KKC K+ ++ND ++ + KL+V +MF+++E FY+S+G++ MT++FW+RS+ +++ +++DCH + F NGVD+RI MCT KDL D T+I HEMGHI+YFMAY L ++R SANSGF E GD + LA +TP +L KIGLL I + +I YL+ SAL+ + F+PFA+ ++ Y+ SVYNG++ ++++N+ +WD+ K QGI PPVER+E FDAGAKYH+A Y R+ S++ Q+ +E+MC+LSGYKGPLH+C F+ S + G K LEM+K G NWR+TMKILTGT + S SLL F+ PL+ WLK KN++L+ + GW
Sbjct: 24 SHNIYQKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLP-EIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 630
BLAST of angiotensin converting enzyme-1 vs. Planmine SMEST
Match: SMESG000005698.1 (SMESG000005698.1) HSP 1 Score: 616.69 bits (1589), Expect = 0.000e+0 Identity = 301/601 (50.08%), Postives = 424/601 (70.55%), Query Frame = 3
Query: 93 RIFDSYGEKSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
+IFDSY + LE YP VC +S+ENCA+ WL +VNEI IRN+NR AN+N++Y +NIN NL L K + L + LKAKKF+ K F SP V++ L+ L + R D + + L++++ +IE IYN PCF C P GEP II++F + KDYD L GYWVAWRN TG+RIRNLF++++ LEN A ++GF D A F L DF+E NF + + ++ I YKELH +VR+CL KYYP +F+K+GPIPAHI G+ WS+ W N+F I+KKC K+ ++ND ++ + KL+V +MF+++E FY+S+G++ MT++FW+RS+ +++ +++DCH + F NGVD+RI MCT KDL D T+I HEMGHI+YFMAY L ++R SANSGF E GD + LA +TP +L KIGLL I + +I YL+ SAL+ + F+PFA+ ++ Y+ SVYNG++ ++++N+ +WD+ K QGI PPVER+E FDAGAKYH+A Y R+ S++ Q+ +E+MC+LSGYKGPLH+C F+ S + G K LEM+K G NWR+TMKILTGT + S SLL F+ PL+ WLK KN++L+ + GW
Sbjct: 11 QIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLP-EIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 610
BLAST of angiotensin converting enzyme-1 vs. Planmine SMEST
Match: SMESG000005704.1 (SMESG000005704.1) HSP 1 Score: 614.764 bits (1584), Expect = 0.000e+0 Identity = 302/612 (49.35%), Postives = 428/612 (69.93%), Query Frame = 3
Query: 60 FNEISNQLFRSRIFDSYGEKSALEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHXXXXXXXXXXXXSPWVKRSLEMLKISSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSFYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHENDLRKEIDENIGKLTVHEMFKLSESFYSSLGMYNMTDKFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEXXXXXXXXXXXXXEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNIKTGW 1895
FN + L + +IFDSY + LE YP VC +S+ENCA+ WL +VNEI IRN+NR AN+N++Y +NIN NL L K + L + LKAKKF+ K F SP V++ L+ L + R D + + L++++ +IE IYN PCF C P GEP II++F + KDYD L GYWVAWRN TG+RIRNLF++++ LEN A ++GF D A F L DF+E NF + + ++ I YKELH +VR+CL KYYP +F+K+GPIPAHI G+ WS+ W N+F I+KKC K+ ++N+ ++ + KL+V +MF+++E FY+S+G++ MT++FW+RS+ +++ +++DCH + F NGVD+RI MCT KDL D T+I HEMGHI+YFMAY L ++R SANSGF E GD + LA +TP +L KIGLL I + +I YL+ SAL+ + F+PFA+ ++ Y+ SVYNG++ ++++N+ +WD+ K QGI PPVER+E FDAGAKYH+A Y R+ S++ Q+ +E+MC+LSGYKGPLH+C F+ S + G K LEM+K G NWR+TMK LTGT + S SLL F+ PL+ WLK KN++L+ + GW
Sbjct: 16 FNSGNLDLNKKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQKWTNIFEIVKKCMKSNYQNNFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLP-EIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGKKNNWRETMKTLTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 626 The following BLAST results are available for this feature:
BLAST of angiotensin converting enzyme-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of angiotensin converting enzyme-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of angiotensin converting enzyme-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of angiotensin converting enzyme-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of angiotensin converting enzyme-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of angiotensin converting enzyme-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of angiotensin converting enzyme-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of angiotensin converting enzyme-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of angiotensin converting enzyme-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of angiotensin converting enzyme-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of angiotensin converting enzyme-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of angiotensin converting enzyme-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of angiotensin converting enzyme-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of angiotensin converting enzyme-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30006268 ID=SMED30006268|Name=angiotensin converting enzyme-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1984bpback to top protein sequence of SMED30006268-orf-1 >SMED30006268-orf-1 ID=SMED30006268-orf-1|Name=SMED30006268-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=628bp MLIKIVSQLFVLLLQFNEISNQLFRSRIFDSYGEKSALEPYPNVCNGHSDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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