DNA repair protein complementing XP-G cells-like protein

Overview
NameDNA repair protein complementing XP-G cells-like protein
Smed IDSMED30006259
Length (bp)2698
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DNA repair protein complementing XP-G cells-like protein (SMED30006259) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA repair protein complementing XP-G cells-like protein (SMED30006259) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DNA repair protein complementing XP-G cells-like protein (SMED30006259) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DNA repair protein complementing XP-G cells-like protein (SMED30006259) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30006259

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30006259h1SMcG0001354 dd_Smed_v4_10808_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30006259h1SMcG0001354 dd_Smed_v4_10808_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006259h1SMcG0001354 dd_Smed_v4_10808_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30006259h1SMcG0001354 dd_Smed_v4_10808_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30006259h1SMcG0001354 dd_Smed_v4_10808_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30006259h1SMcG0001354 Contig4459GPL15192PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Human
Match: ERCC5 (ERCC excision repair 5, endonuclease [Source:HGNC Symbol;Acc:HGNC:3437])

HSP 1 Score: 177.563 bits (449), Expect = 5.223e-45
Identity = 106/301 (35.22%), Postives = 170/301 (56.48%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +WQ    E +E   +NL  + + +++Q       AA+++ + + E+++LL++FGIPYI++P EAEAQCA L+  + T+GTIT+DSDIWLFG   VY++ F+++     Y        LGL ++ +I +A L GSDYT G+  +G V AMEIL EF    ++     +L+  + WH+       K + NP     +K+    QL   FP+  V +AY +P+VD+S+  F+W +P +D++ +F Q   GW R K  E L  V K   +++   +   +D F      E  ++KR  S+RL  A
Sbjct:  559 EWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLE----PLLKFSEWWHEAQKN--PKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLR---IDSFFRLAQQEKEDAKRIKSQRLNRA 850          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Human
Match: ERCC5 (ERCC excision repair 5, endonuclease [Source:HGNC Symbol;Acc:HGNC:3437])

HSP 1 Score: 177.563 bits (449), Expect = 7.413e-45
Identity = 106/301 (35.22%), Postives = 170/301 (56.48%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +WQ    E +E   +NL  + + +++Q       AA+++ + + E+++LL++FGIPYI++P EAEAQCA L+  + T+GTIT+DSDIWLFG   VY++ F+++     Y        LGL ++ +I +A L GSDYT G+  +G V AMEIL EF    ++     +L+  + WH+       K + NP     +K+    QL   FP+  V +AY +P+VD+S+  F+W +P +D++ +F Q   GW R K  E L  V K   +++   +   +D F      E  ++KR  S+RL  A
Sbjct:  727 EWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLE----PLLKFSEWWHEAQKN--PKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLR---IDSFFRLAQQEKEDAKRIKSQRLNRA 1018          

HSP 2 Score: 156.377 bits (394), Expect = 3.053e-38
Identity = 101/314 (32.17%), Postives = 167/314 (53.18%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLV---------EKRKSVSHNKSEADDLFQLP------------ENEYYDTISMNQ---FETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLND--LPATINTRKILSRNDGYLMMI 942
            MGVQGLW +L  +GR +   +LEGK+LA+D+SIWLNQAL     R G    N HL  LF R+CKLLF++I+P+FVFDG +P LKK+T++ RR+ + L    S K    ++   +K++ +         E   S++  + E +DL+ LP            E+E      MNQ    + EF            F +   +++ES  F S+P EV+HEI+   +   K +R  +       + +  D+FS  Q++ LL +N L Q +E ++  MN +++    G +R+Q  ++      + +R+++S +  + ++I
Sbjct:    1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRE-NDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEF------------FHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHS----GHIRRQYEDEGGFLKEVESRRVVSEDTSHYILI 292          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Human
Match: BIVM-ERCC5 (BIVM-ERCC5 readthrough [Source:HGNC Symbol;Acc:HGNC:43690])

HSP 1 Score: 177.178 bits (448), Expect = 1.213e-44
Identity = 106/301 (35.22%), Postives = 172/301 (57.14%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +WQ    E +E   +NL  + + +++Q       AA+++ + + E+++LL++FGIPYI++P EAEAQCA L+  + T+GTIT+DSDIWLFG   VY++ F+++     Y        LGL ++ +I +A L GSDYT G+  +G V AMEIL EF    ++     +L+  + WH+  ++   K + NP     +K+    QL   FP+  V +AY +P+VD+S+  F+W +P +D++ +F Q   GW R K  E L  V K   +++   +   +D F      E  ++KR  S+RL  A
Sbjct:  952 EWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLE----PLLKFSEWWHE--AQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLR---IDSFFRLAQQEKEDAKRIKSQRLNRA 1243          

HSP 2 Score: 114.775 bits (286), Expect = 3.242e-25
Identity = 84/285 (29.47%), Postives = 145/285 (50.88%), Query Frame = 1
Query:  190 DMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLV---------EKRKSVSHNKSEADDLFQLP------------ENEYYDTISMNQ---FETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLND--LPATINTRKILSRNDGYLMMI 942
            ++SIWLNQAL     R G    N HL  LF R+CKLLF++I+P+FVFDG +P LKK+T++ RR+ + L    S K    ++   +K++ +         E   S++  + E +DL+ LP            E+E      MNQ    + EF            F +   +++ES  F S+P EV+HEI+   +   K +R  +       + +  D+FS  Q++ LL +N L Q +E ++  MN +++    G +R+Q  ++      + +R+++S +  + ++I
Sbjct:  255 NISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRE-NDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEF------------FHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHS----GHIRRQYEDEGGFLKEVESRRVVSEDTSHYILI 517          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Human
Match: ERCC5 (ERCC excision repair 5, endonuclease [Source:HGNC Symbol;Acc:HGNC:3437])

HSP 1 Score: 177.178 bits (448), Expect = 1.271e-44
Identity = 106/301 (35.22%), Postives = 172/301 (57.14%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +WQ    E +E   +NL  + + +++Q       AA+++ + + E+++LL++FGIPYI++P EAEAQCA L+  + T+GTIT+DSDIWLFG   VY++ F+++     Y        LGL ++ +I +A L GSDYT G+  +G V AMEIL EF    ++     +L+  + WH+  ++   K + NP     +K+    QL   FP+  V +AY +P+VD+S+  F+W +P +D++ +F Q   GW R K  E L  V K   +++   +   +D F      E  ++KR  S+RL  A
Sbjct: 1181 EWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLE----PLLKFSEWWHE--AQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLR---IDSFFRLAQQEKEDAKRIKSQRLNRA 1472          

HSP 2 Score: 114.775 bits (286), Expect = 3.250e-25
Identity = 84/285 (29.47%), Postives = 145/285 (50.88%), Query Frame = 1
Query:  190 DMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLV---------EKRKSVSHNKSEADDLFQLP------------ENEYYDTISMNQ---FETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLND--LPATINTRKILSRNDGYLMMI 942
            ++SIWLNQAL     R G    N HL  LF R+CKLLF++I+P+FVFDG +P LKK+T++ RR+ + L    S K    ++   +K++ +         E   S++  + E +DL+ LP            E+E      MNQ    + EF            F +   +++ES  F S+P EV+HEI+   +   K +R  +       + +  D+FS  Q++ LL +N L Q +E ++  MN +++    G +R+Q  ++      + +R+++S +  + ++I
Sbjct:  484 NISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRE-NDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEF------------FHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHS----GHIRRQYEDEGGFLKEVESRRVVSEDTSHYILI 746          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Human
Match: BIVM-ERCC5 (BIVM-ERCC5 readthrough [Source:HGNC Symbol;Acc:HGNC:43690])

HSP 1 Score: 177.178 bits (448), Expect = 1.271e-44
Identity = 106/301 (35.22%), Postives = 172/301 (57.14%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +WQ    E +E   +NL  + + +++Q       AA+++ + + E+++LL++FGIPYI++P EAEAQCA L+  + T+GTIT+DSDIWLFG   VY++ F+++     Y        LGL ++ +I +A L GSDYT G+  +G V AMEIL EF    ++     +L+  + WH+  ++   K + NP     +K+    QL   FP+  V +AY +P+VD+S+  F+W +P +D++ +F Q   GW R K  E L  V K   +++   +   +D F      E  ++KR  S+RL  A
Sbjct: 1181 EWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLE----PLLKFSEWWHE--AQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLR---IDSFFRLAQQEKEDAKRIKSQRLNRA 1472          

HSP 2 Score: 114.775 bits (286), Expect = 3.250e-25
Identity = 84/285 (29.47%), Postives = 145/285 (50.88%), Query Frame = 1
Query:  190 DMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLV---------EKRKSVSHNKSEADDLFQLP------------ENEYYDTISMNQ---FETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLND--LPATINTRKILSRNDGYLMMI 942
            ++SIWLNQAL     R G    N HL  LF R+CKLLF++I+P+FVFDG +P LKK+T++ RR+ + L    S K    ++   +K++ +         E   S++  + E +DL+ LP            E+E      MNQ    + EF            F +   +++ES  F S+P EV+HEI+   +   K +R  +       + +  D+FS  Q++ LL +N L Q +E ++  MN +++    G +R+Q  ++      + +R+++S +  + ++I
Sbjct:  484 NISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRE-NDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEF------------FHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHS----GHIRRQYEDEGGFLKEVESRRVVSEDTSHYILI 746          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Celegans
Match: xpg-1 (XPG (Xeroderma Pigmentosum group G) DNA repair gene homolog [Source:UniProtKB/TrEMBL;Acc:O44737])

HSP 1 Score: 118.627 bits (296), Expect = 4.838e-27
Identity = 73/228 (32.02%), Postives = 118/228 (51.75%), Query Frame = 1
Query: 1876 YQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHI-----FKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSH-FKVLENFKMWHDKWSKLLEK----YKGNPERKR-------FLRFQLDHK---------FPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGW 2481
            Y++ ++ L   GIP+IESPGEAEAQC  LE+  L +G +++DSD+W FG   VY+H+FS++   + Y  +        K+  L ++  I IALLSG DY  G+  +G + A+E+++E+ +  ID ++  KV+EN  M      +LL+     +   P+ KR        LR  +              +Q  V AY  P+VD S +   W + +I  +      ++ W
Sbjct:  469 YRDLQEFLTNAGIPWIESPGEAEAQCVELERLGLVDGVVSDDSDVWAFGAQHVYRHMFSKNRRVQRYGEQTTANRDNCKLFCLQREDYISIALLSGGDYCAGLVKVGAIGALELVSEYVECRIDNTNDLKVIENRIM------RLLKNVESLFLTAPDDKRVASRNAMMLRRHVTEANDMENIKCVCSNQDAVHAYLHPIVDSSSEKLRWRQMNIPLIRRILHQRLQW 690          

HSP 2 Score: 107.071 bits (266), Expect = 2.160e-23
Identity = 90/256 (35.16%), Postives = 131/256 (51.17%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQA-LRSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPS-PSLKKETIINRRKLRQ---------LKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQ-LPENE-YYDTISMNQF-ETEFGISDTALDYLSNFSSMNEVNLE--SGSFKSMPLEVQHEI-IRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTS 819
            MG+ GLW I+  T  +I L  LEGK LAID+SIW+ QA L    D P  HL +L  R+ KLLFYKI+PVFVFDGP  P LK++ +  RR+ RQ          K  K ++I S  +D +     +++  S S  K   +D+++ +P    Y D  S +Q  +  +G  + +    S+   +  V  E  S  F S  LE+Q  +  R I +  R      +   + +    FS+ Q+QRLL R  L  ++E L  S
Sbjct:    1 MGITGLWKIVEPTATEIPLECLEGKKLAIDVSIWIYQAQLAYPSDQPFPHLRLLVNRLSKLLFYKIRPVFVFDGPQVPPLKRQVLEARRQKRQNDDDILKNSKKMGKLKEIASGGLDDVALANAIKEVISPS-KKVILNDIYKDIPSTSTYLDKPSAHQNDQLVYGNIEDSDSDDSDIIIVPTVKEERISKQFTSRKLEIQSLVEKREIMRNSRL-----RPDMIPQDSKSFSNFQMQRLLRRGRLNAEIEQLAKS 250          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Celegans
Match: crn-1 (Flap endonuclease 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9N3T2])

HSP 1 Score: 87.0409 bits (214), Expect = 7.852e-18
Identity = 49/148 (33.11%), Postives = 80/148 (54.05%), Query Frame = 1
Query: 1825 KEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE-----IDQSHF 2244
            KE  K E +   ++++   EAK LL + GIP +E+P EAEAQCA L K     GT+TED D   FG  ++ +H     ++    + ++L    + + LS +  I + +L G DY   + G+GP  A+E++ +  + E     IDQ+ +
Sbjct:  121 KEAEKFERRLVKVTKQQNDEAKRLLGLMGIPVVEAPCEAEAQCAHLVKAGKVFGTVTEDMDALTFGSTVLLRHFLAPVAKKIPIKEFNLSLALEEMKLSVEEFIDLCILLGCDYCGTIRGVGPKKAVELIRQHKNIETILENIDQNKY 268          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Celegans
Match: crn-1 (Flap endonuclease 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9N3T2])

HSP 1 Score: 87.0409 bits (214), Expect = 7.852e-18
Identity = 49/148 (33.11%), Postives = 80/148 (54.05%), Query Frame = 1
Query: 1825 KEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE-----IDQSHF 2244
            KE  K E +   ++++   EAK LL + GIP +E+P EAEAQCA L K     GT+TED D   FG  ++ +H     ++    + ++L    + + LS +  I + +L G DY   + G+GP  A+E++ +  + E     IDQ+ +
Sbjct:  121 KEAEKFERRLVKVTKQQNDEAKRLLGLMGIPVVEAPCEAEAQCAHLVKAGKVFGTVTEDMDALTFGSTVLLRHFLAPVAKKIPIKEFNLSLALEEMKLSVEEFIDLCILLGCDYCGTIRGVGPKKAVELIRQHKNIETILENIDQNKY 268          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Celegans
Match: gen-1 (GEN1 Holliday junction resolvase homolog [Source:UniProtKB/TrEMBL;Acc:Q22418])

HSP 1 Score: 81.6481 bits (200), Expect = 6.693e-16
Identity = 75/248 (30.24%), Postives = 110/248 (44.35%), Query Frame = 1
Query: 1894 LLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARA-------YSLKHIFKVLGLSQDLMICIALLSGSDY-TPGVYGIGPVIAMEILAEFSD---PEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPD----QRVVDAYNRPLVDESEQPFIWSRPS-IDQLLDFAQSKIGWERLKVIEMLNV-VSKNYGSKKLFCQKSILDYFTDSK 2586
            LL   GI  I +PG+ EAQCA LE   +T+G IT D D +LFGG  +Y+  F+   S+ A        SL  +F    +S+  +I  A+L G DY   GV  IG V   +IL EF D    EID     +L+ F  +  +      +      R R  ++     FP+       +  Y RP V  SE P I  R +   Q+ +    + GW   +  + L + + +         Q  I D+F  +K
Sbjct:  119 LLTELGIKVIIAPGDGEAQCARLEDLGVTSGCITTDFDYFLFGGKNLYRFDFTAGTSSTACLHDIMHLSLGRMFMEKKVSRPHLISTAILLGCDYFQRGVQNIGIVSVFDILGEFGDDGNEEIDPH--VILDRFASYVREEIPARSEDTQRKLRLRRKKYNFPVGFPNCDAVHNAITMYLRPPV-SSEIPKIIPRAANFQQVAEIMMKECGWPATRTQKELALSIRRKVHLTTTVAQTRIPDFFAATK 363          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Celegans
Match: gen-1 (GEN1 Holliday junction resolvase homolog [Source:UniProtKB/TrEMBL;Acc:Q22418])

HSP 1 Score: 81.6481 bits (200), Expect = 6.693e-16
Identity = 75/248 (30.24%), Postives = 110/248 (44.35%), Query Frame = 1
Query: 1894 LLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARA-------YSLKHIFKVLGLSQDLMICIALLSGSDY-TPGVYGIGPVIAMEILAEFSD---PEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPD----QRVVDAYNRPLVDESEQPFIWSRPS-IDQLLDFAQSKIGWERLKVIEMLNV-VSKNYGSKKLFCQKSILDYFTDSK 2586
            LL   GI  I +PG+ EAQCA LE   +T+G IT D D +LFGG  +Y+  F+   S+ A        SL  +F    +S+  +I  A+L G DY   GV  IG V   +IL EF D    EID     +L+ F  +  +      +      R R  ++     FP+       +  Y RP V  SE P I  R +   Q+ +    + GW   +  + L + + +         Q  I D+F  +K
Sbjct:  119 LLTELGIKVIIAPGDGEAQCARLEDLGVTSGCITTDFDYFLFGGKNLYRFDFTAGTSSTACLHDIMHLSLGRMFMEKKVSRPHLISTAILLGCDYFQRGVQNIGIVSVFDILGEFGDDGNEEIDPH--VILDRFASYVREEIPARSEDTQRKLRLRRKKYNFPVGFPNCDAVHNAITMYLRPPV-SSEIPKIIPRAANFQQVAEIMMKECGWPATRTQKELALSIRRKVHLTTTVAQTRIPDFFAATK 363          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Fly
Match: mus201 (gene:FBgn0002887 transcript:FBtr0100473)

HSP 1 Score: 183.341 bits (464), Expect = 5.507e-47
Identity = 112/299 (37.46%), Postives = 164/299 (54.85%), Query Frame = 1
Query: 1792 ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFS-----DPEI-DQSHFKVLENFKMW--HDKWSKLLEKYKGN-PERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            E ++E   NL +E  ++E +         S+S+R   + ++LL++FGIPYI +P EAEAQCAFL   +LT+GTIT+DSDIWLFGG  VYK+ F+++     +  + I +    ++  +I +A L GSDYT G++GIG V A+EILA FS      P I +QS  + L  F+ W    K S L          RK+    +L   FP   VV+AY  P +D++   F W  P ++ + +F +   GW   K  ++L  V K    KK+  Q SI +YFT      L   +   SKR++LA
Sbjct:  825 EELQELATNLAQERKELEIERNRQDRMGMSISQRMSIDCQELLRLFGIPYIVAPMEAEAQCAFLNATDLTHGTITDDSDIWLFGGRTVYKNFFAQNKHVMEFRAEQIEQTFNCNRGKLIQLACLVGSDYTTGIHGIGAVTALEILASFSGQDANGPGICNQSVLQTLIKFRDWWQAHKCSNLPPGSSARLALRKKLKNIELHEGFPSGAVVEAYLAPTIDDNRDAFSWGTPDVESIREFTRKSFGWTTSKTDDILMPVMKKINEKKI--QGSIRNYFTAKSA--LRVQQPHVSKRVQLA 1119          

HSP 2 Score: 151.369 bits (381), Expect = 6.946e-37
Identity = 89/268 (33.21%), Postives = 151/268 (56.34%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRS-----GIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEK--------------RKSVSHNKSEADDLFQLPENEYYDTISMNQFETEFGIS--------DTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMN 825
            MGV GLW ++   G+ + + +LEGK+LA+D+SIWL+Q ++      G    N HL  LF R+CKLL+Y+++PVF+FDG  P LK++TI  R++ R     ++++I++ ++  L K+K+V++              ++     K++ DDLF+LPE     ++  NQ E+E   S        D +    S  SS+  ++++S  F+++P +V+HEI+  I KE R   +  +   L    D+F S Q++RLL R  +Q+ +E     M 
Sbjct:    1 MGVTGLWKLIEPCGKPVPVETLEGKILAVDISIWLHQVVKGFQDNKGSALSNAHLLGLFHRLCKLLYYRVRPVFIFDGCVPQLKRDTIARRQQQRNKLSNEADRIQALLLQSLAKEKVVQQALGKNAELLLKSPVKRPPPAKKNDEDDLFKLPELPAA-SVQDNQDESEQDTSASASDSSFDESTARHSYNSSLQAIDVKSQHFRNLPADVRHEILTDI-KETRKQSSWGRLHELPARSDDFCSFQMKRLLKRRAVQESLEQAEQEMG 266          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Fly
Match: mus201 (gene:FBgn0002887 transcript:FBtr0346117)

HSP 1 Score: 183.341 bits (464), Expect = 5.507e-47
Identity = 112/299 (37.46%), Postives = 164/299 (54.85%), Query Frame = 1
Query: 1792 ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFS-----DPEI-DQSHFKVLENFKMW--HDKWSKLLEKYKGN-PERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            E ++E   NL +E  ++E +         S+S+R   + ++LL++FGIPYI +P EAEAQCAFL   +LT+GTIT+DSDIWLFGG  VYK+ F+++     +  + I +    ++  +I +A L GSDYT G++GIG V A+EILA FS      P I +QS  + L  F+ W    K S L          RK+    +L   FP   VV+AY  P +D++   F W  P ++ + +F +   GW   K  ++L  V K    KK+  Q SI +YFT      L   +   SKR++LA
Sbjct:  825 EELQELATNLAQERKELEIERNRQDRMGMSISQRMSIDCQELLRLFGIPYIVAPMEAEAQCAFLNATDLTHGTITDDSDIWLFGGRTVYKNFFAQNKHVMEFRAEQIEQTFNCNRGKLIQLACLVGSDYTTGIHGIGAVTALEILASFSGQDANGPGICNQSVLQTLIKFRDWWQAHKCSNLPPGSSARLALRKKLKNIELHEGFPSGAVVEAYLAPTIDDNRDAFSWGTPDVESIREFTRKSFGWTTSKTDDILMPVMKKINEKKI--QGSIRNYFTAKSA--LRVQQPHVSKRVQLA 1119          

HSP 2 Score: 151.369 bits (381), Expect = 6.946e-37
Identity = 89/268 (33.21%), Postives = 151/268 (56.34%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRS-----GIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEK--------------RKSVSHNKSEADDLFQLPENEYYDTISMNQFETEFGIS--------DTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMN 825
            MGV GLW ++   G+ + + +LEGK+LA+D+SIWL+Q ++      G    N HL  LF R+CKLL+Y+++PVF+FDG  P LK++TI  R++ R     ++++I++ ++  L K+K+V++              ++     K++ DDLF+LPE     ++  NQ E+E   S        D +    S  SS+  ++++S  F+++P +V+HEI+  I KE R   +  +   L    D+F S Q++RLL R  +Q+ +E     M 
Sbjct:    1 MGVTGLWKLIEPCGKPVPVETLEGKILAVDISIWLHQVVKGFQDNKGSALSNAHLLGLFHRLCKLLYYRVRPVFIFDGCVPQLKRDTIARRQQQRNKLSNEADRIQALLLQSLAKEKVVQQALGKNAELLLKSPVKRPPPAKKNDEDDLFKLPELPAA-SVQDNQDESEQDTSASASDSSFDESTARHSYNSSLQAIDVKSQHFRNLPADVRHEILTDI-KETRKQSSWGRLHELPARSDDFCSFQMKRLLKRRAVQESLEQAEQEMG 266          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Fly
Match: Fen1 (gene:FBgn0025832 transcript:FBtr0087075)

HSP 1 Score: 85.1149 bits (209), Expect = 4.235e-17
Identity = 50/162 (30.86%), Postives = 85/162 (52.47%), Query Frame = 1
Query: 1834 HKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE-----IDQSHFKVLENFKMWHDKWSKLL 2295
             K   +   +++ + +EAK+LL + G+PY+++P EAEAQCA L K      T TED D   FG   + +++    +R    + +S   + + L ++    I + +L G DY   + GIGP  A+E++  + D E     +D S + V EN   W+ K ++ L
Sbjct:  124 EKFNRRLVRVTKEHAKEAKELLTLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTFGSTKLLRYLTYSEARKMPVKEFSYDKLLEGLAINNREFIDLCILLGCDYCESIKGIGPKRAIELINTYRDIETILDNLDSSKYTVPEN---WNYKVAREL 282          

HSP 2 Score: 51.6026 bits (122), Expect = 2.319e-6
Identity = 50/157 (31.85%), Postives = 74/157 (47.13%), Query Frame = 1
Query:  103 MGVQGLWNILHSTG----RDIDLSSLEGKVLAIDMSIWLNQ---ALRS-GI------DSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEK--RKSVSHNKSEADDLFQLPENEYYDT 525
            MG+ GL  ++        R+ ++    G+ +AID S+ L Q   A+RS G         P  HL  +F R  +LL   IKPV+VFDG  P LK   +  R + R+ + EK+ K  ++  D    +K   +  R +  H K EA +L  L    Y D 
Sbjct:    1 MGILGLSKLIADLAPQAIRESEMKHFFGRKVAIDASMCLYQFLIAVRSEGAQLATVNGDPTSHLMGMFYRTIRLLDNGIKPVYVFDGKPPDLKSGELAKRAERRE-EAEKALKAATDAGDDAGIEKFNRRLVRVTKEHAK-EAKELLTLMGVPYVDA 155          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Fly
Match: Gen (gene:FBgn0263831 transcript:FBtr0077176)

HSP 1 Score: 69.707 bits (169), Expect = 8.497e-12
Identity = 38/108 (35.19%), Postives = 54/108 (50.00%), Query Frame = 1
Query: 1879 QEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARA-------------YSLKHIFKVLGLSQDLMICIALLSGSDYTP 2163
            ++ + LL   GI  ++ PGEAEA CAFL K  L +G I++DSD + +G   VY     R+FS                Y ++ I   +   Q  +I +ALL G DY P
Sbjct:  124 KQCETLLLSMGIQCVQGPGEAEAYCAFLNKHGLVDGVISQDSDCFAYGAVRVY-----RNFSVSTQGAQAAAGGAVDIYDMREITSRMDFGQQKIIVMALLCGCDYCP 226          

HSP 2 Score: 66.2402 bits (160), Expect = 1.100e-10
Identity = 34/93 (36.56%), Postives = 55/93 (59.14%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGID---SPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR 372
            MGV+ LW +L        ++ L GK +AID++ W+ ++L   +D    P  HL+ LF R C L++ ++ PVFV +G +P LK + I  R +L+
Sbjct:    1 MGVKELWGVLTPHCERKPINELRGKKVAIDLAGWVCESLNV-VDYFVHPRHHLKNLFFRTCYLIWEQVTPVFVLEGVAPKLKSQVIAKRNELQ 92          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Fly
Match: tos (gene:FBgn0015553 transcript:FBtr0081131)

HSP 1 Score: 50.447 bits (119), Expect = 6.906e-6
Identity = 30/107 (28.04%), Postives = 52/107 (48.60%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQA-------LRSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKI 402
            MG+ GL   +      + L  + G  +A+D   WL++        L  G D+ +V+++   + +  LL Y IKP+ VFDG     K  T   RR  R+  +E++ ++
Sbjct:    1 MGITGLIPFVGKASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEKLARGEDT-DVYIQYCLKYVNMLLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAEL 106          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Zebrafish
Match: ercc5 (excision repair cross-complementation group 5 [Source:ZFIN;Acc:ZDB-GENE-050327-28])

HSP 1 Score: 168.318 bits (425), Expect = 2.648e-42
Identity = 90/234 (38.46%), Postives = 137/234 (58.55%), Query Frame = 1
Query: 1858 SMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLE--KYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKK 2541
            +++ +  QE+++LL++FG+P+I +P EAEAQCA L++ + T+GTIT+DSDIWLFGG  VY++ F+++     Y +  +   LGL +  +I +A L GSDYT G+ G+G V  MEIL EF       +  + L     W   W++  E  K   NP+    +K+    Q+   FP+  V  AY +P VD+S+  F W RP +D + +F QS+ GW   K  E L  V K   S++
Sbjct:  653 TVTGQMCQESQELLRLFGVPFIVAPMEAEAQCAALDRLDQTHGTITDDSDIWLFGGRHVYRNFFNQNKYVEHYQIVDMQNQLGLDRSKLINLAYLLGSDYTEGIPGVGYVTGMEILNEFPG-----AGLEPLVQLSEW---WTEAQENKKLSVNPKDTKVKKKLRNLQIHPGFPNPAVAQAYLQPSVDQSDASFSWGRPHLDLIKEFCQSRFGWSSRKTEETLQPVLKQLQSQQ 878          

HSP 2 Score: 155.606 bits (392), Expect = 2.772e-38
Identity = 101/305 (33.11%), Postives = 164/305 (53.77%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEA------------DDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFS-----SMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGD---EFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMI 942
            MGV GLW +L STG+ I+  +LEGK+LA+D+SIWLNQA+     R G    N HL  LF R+CKLLF++I+PVFV+DG +P LKK+T+  RR+ R+    +S +    ++   +K++ +  R ++  N  E+            DD++ LP     D    +  E E    D AL   S F      + + V++ S  F  MP E++HEI++ + +     ++  + + L+K  +   EFS  Q+  LL RN L Q++E +   MN R++    G    QQ  ++      R+++S +  + ++I
Sbjct:    1 MGVHGLWKLLESTGKPINPETLEGKILAVDISIWLNQAVKGVRDRDGNAVQNAHLLTLFHRLCKLLFFRIRPVFVYDGDAPLLKKQTLAVRRQRREETNRESRQTSEKLLQTFLKRQAI--RAALGENSQESAPSLSSVRRDEHDDIYVLPALPPEDDRQESSSEEEKD-GDEALHNYSRFQEELCDNPDAVDINSEQFSLMPPEIKHEILKEMKE-----FSKRRRTLLHKPPERSGEFSQYQLAGLLQRNRLNQRLECVEQEMNQRSS----GGHTDQQNTEI------RRLVSEDSSHYILI 287          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Zebrafish
Match: ercc5 (excision repair cross-complementation group 5 [Source:ZFIN;Acc:ZDB-GENE-050327-28])

HSP 1 Score: 152.525 bits (384), Expect = 6.565e-40
Identity = 97/265 (36.60%), Postives = 145/265 (54.72%), Query Frame = 1
Query: 1876 YQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLE--KYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQ---SKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLAT 2643
            Y E+ +LL++FG+P+I +P EAEAQCA L++ + T+GTIT+DSDIWLFGG  VY++ F+++     Y +  +   LGL +  +I +A L GSDYT G+ G+G V  MEIL EF       +  + L     W   W++  E  K   NP+    +K+    Q+   FP+  V  AY +P VD+S+  F W RP +D + ++     S+ GW   K  E L  V K   S++   Q  I  +F   + D     ++  S+RLR A 
Sbjct:    2 YIESHELLRLFGVPFIVAPMEAEAQCAALDRLDQTHGTITDDSDIWLFGGRHVYRNFFNQNKYVEHYQIVDMQNQLGLDRSKLINLAYLLGSDYTEGIPGVGYVTGMEILNEFPG-----AGLEPLVQLSEW---WTEAQENKKLSVNPKDTKVKKKLRNLQIHPGFPNPAVAQAYLQPSVDQSDASFSWGRPHLDLIKEYPSPKPSRFGWSSRKTEETLQPVLKQLQSQQ--TQLRIDSFFRLEQQDR----QQIRSERLRRAV 252          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Zebrafish
Match: ercc5 (excision repair cross-complementation group 5 [Source:ZFIN;Acc:ZDB-GENE-050327-28])

HSP 1 Score: 141.354 bits (355), Expect = 2.969e-37
Identity = 88/257 (34.24%), Postives = 140/257 (54.47%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHN------------KSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFS-----SMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGD---EFSSLQIQRLLSRNTLQQK 798
            MGV GLW +L STG+ I+  +LEGK+LA+D+SIWLNQA+     R G    N HL  LF R+CKLLF++I+PVFV+DG +P LKK+T+  RR+ R+    +S +    ++   +K++ +  R ++  N            + E DD++ LP     D    +  E E    D AL   S F      + + V++ S  F  MP E++HEI++ + +     ++  + + L+K  +   EFS  Q+  LL R+   ++
Sbjct:    1 MGVHGLWKLLESTGKPINPETLEGKILAVDISIWLNQAVKGVRDRDGNAVQNAHLLTLFHRLCKLLFFRIRPVFVYDGDAPLLKKQTLAVRRQRREETNRESRQTSEKLLQTFLKRQAI--RAALGENSQESAPSLSSVRRDEHDDIYVLPALPPEDDRQESSSEEEKD-GDEALHNYSRFQEELCDNPDAVDINSEQFSLMPPEIKHEILKEMKE-----FSKRRRTLLHKPPERSGEFSQYQLAGLLQRSVWSRR 249          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Zebrafish
Match: zgc:110269 (zgc:110269 [Source:NCBI gene;Acc:550274])

HSP 1 Score: 80.8777 bits (198), Expect = 9.832e-16
Identity = 42/123 (34.15%), Postives = 66/123 (53.66%), Query Frame = 1
Query: 1846 SQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHV-FSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAE 2211
            SQ+ +    + QE   LL + G+P I++PGEAEA CA L K    N   +ED D   FGG ++ + +   RD     YSL  + + L L  +  + + +L G DY   + G+GP  A++++ E
Sbjct:  100 SQSPNTGSAFNQECLRLLHLMGVPCIKAPGEAEALCAHLAKIGTVNAVASEDMDTLAFGGTVLLRQLNAKRDSEITEYSLPKLLEALQLKYEEFVDLCILLGCDYCDKIGGLGPSRALKLIKE 222          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Zebrafish
Match: FO834823.1 (pep chromosome:GRCz11:4:288633:292031:1 gene:ENSDARG00000112451.1 transcript:ENSDART00000183304.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:FO834823.1)

HSP 1 Score: 75.8702 bits (185), Expect = 6.472e-15
Identity = 37/110 (33.64%), Postives = 63/110 (57.27%), Query Frame = 1
Query: 1846 SQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYK--HVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGV 2169
            ++A S      +E   +L   G+P++ + GEAEA CAFL+ + L +G IT D D +L+G   VY+  ++ ++D     Y    + + LGL ++ ++ +A+L G DY P V
Sbjct:   97 TKAKSRFNAVLRECAQMLDCLGVPWVTAAGEAEAMCAFLDSQGLVDGCITNDGDAFLYGARTVYRNFNMTTKDPQVDCYQSSRVQEELGLCRETLVGLAVLLGCDYIPKV 206          

HSP 2 Score: 68.5514 bits (166), Expect = 2.391e-12
Identity = 36/95 (37.89%), Postives = 54/95 (56.84%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQA-----LRSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR 372
            MGV  LW+IL    + + L SL GK LA+D+S+W+ +A     +   +  P  HL  LF R+  L    +K VFV +G +P +K ET+  R ++R
Sbjct:    1 MGVTELWSILEPVRQSVSLYSLSGKTLAVDLSLWVCEAQHVQGMMGRVTKP--HLRNLFFRVSSLTLMGVKLVFVMEGEAPKIKAETMSKRTEMR 93          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Xenopus
Match: amigo1 (adhesion molecule with Ig-like domain 1 [Source:Xenbase;Acc:XB-GENE-922133])

HSP 1 Score: 172.555 bits (436), Expect = 2.486e-43
Identity = 111/311 (35.69%), Postives = 168/311 (54.02%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLL--EKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLD--------FAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +WQ    E +E    NLY +   +++Q       AA+++ +   E+++LL++FGIPYI +P EAEAQCA L+  + T+GTIT+DSDIWLFG   VYK+ F+++     Y    I   LGL +  +I +A L GSDYT G+  +G V AMEIL EF          + L  FK W   W++    +K + NP     +K+  R ++   FP+  V +AY +P+VDES+  F W RP ++Q+ +        F   + GW R K  E+L  V K   +++   +   +D F   +  E +  K   S+RLR A
Sbjct:  762 EWQDISVEELESLENNLYVQQTSLQAQRQQQERIAATVTGQMCLESQELLRLFGIPYIVAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYKNFFTQNKHVEYYQYADIHNQLGLDRSKLINLAYLLGSDYTEGIPTVGYVSAMEILNEFP-----AQGLESLLQFKEW---WTEAQKDKKMRPNPHDTKVKKKLRRLEIHQGFPNPAVANAYLKPVVDESKAAFCWGRPDLEQIREYPLLFINIFNTCRFGWYRSKTDEVLLPVLKQINAQQTQLR---IDSFFRLEQHEAIGLK---SQRLRRA 1058          

HSP 2 Score: 158.688 bits (400), Expect = 5.169e-39
Identity = 95/305 (31.15%), Postives = 166/305 (54.43%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSP-----NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKS--------------EADDLFQLP---ENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMI 942
            MGVQGLW +L  TGR I+  +LEGK+LAID+SIWLNQA++   D       N HL  LF R+CKLLF++I+P+FVFDG +P LK++T+  RR+ +     +++K    ++   +K++ +  + ++S NK               E DDL+ LP   +NE Y +    +   E  ++         F++ + V++ES  F S+P EV+HEI+   +   K +R  +       + +  ++FS  Q+  LL +N L + ++++R  +N + +  V      +        + TR+++S ++ + ++I
Sbjct:    1 MGVQGLWKLLECTGRPINAETLEGKILAIDISIWLNQAVKGARDRQGNAIQNAHLLTLFHRLCKLLFFRIRPIFVFDGEAPLLKRQTLAKRRQRKDNASNEAKKTHEKLLRTFLKRQAI--KAALSGNKQSNDELPSFSKVRRKETDDLYILPPLEDNEKYSSEEEEERAWEERMTQKQRLQEEFFANPSSVDIESEEFISLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEDSNDFSQYQLSGLLKKNNLNKCIDNVRKELNQQYSGEVQAQFEAE--GGFLKEVETRRLVSEDNSHYILI 296          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Xenopus
Match: amigo1 (adhesion molecule with Ig-like domain 1 [Source:Xenbase;Acc:XB-GENE-922133])

HSP 1 Score: 169.474 bits (428), Expect = 2.337e-42
Identity = 111/311 (35.69%), Postives = 169/311 (54.34%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLL--EKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLD--------FAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +WQ    E +E    NLY +   +++Q       AA+++ +   E+++LL++FGIPYI +P EAEAQCA L+  + T+GTIT+DSDIWLFG   VYK+ F+++     Y    I   LGL +  +I +A L GSDYT G+  +G V AMEIL EF    ++      L  FK W   W++    +K + NP     +K+  R ++   FP+  V +AY +P+VDES+  F W RP ++Q+ +        F   + GW R K  E+L  V K   +++   +   +D F   +  E +  K   S+RLR A
Sbjct:  734 EWQDISVEELESLENNLYVQQTSLQAQRQQQERIAATVTGQMCLESQELLRLFGIPYIVAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYKNFFTQNKHVEYYQYADIHNQLGLDRSKLINLAYLLGSDYTEGIPTVGYVSAMEILNEFPAQGLES-----LLQFKEW---WTEAQKDKKMRPNPHDTKVKKKLRRLEIHQGFPNPAVANAYLKPVVDESKAAFCWGRPDLEQIREYPLLFINIFNTCRFGWYRSKTDEVLLPVLKQINAQQTQLR---IDSFFRLEQHEAIGLK---SQRLRRA 1030          

HSP 2 Score: 103.99 bits (258), Expect = 5.512e-22
Identity = 71/260 (27.31%), Postives = 135/260 (51.92%), Query Frame = 1
Query:  193 MSIWLNQALRSGIDSP-----NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSN--FSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMI 942
            +SIWLNQA++   D       N HL  LF R+CKLLF++I+P+FVFDG +P LK++T+  RR+ +     +++K    ++   +K++ +  + ++S NK      + L     Y   S  + E  +    T    L    F++ + V++ES  F S+P EV+HEI+   +   K +R  +       + +  ++FS  Q+  LL +N L + ++++R  +N + +  V      +        + TR+++S ++ + ++I
Sbjct:  263 ISIWLNQAVKGARDRQGNAIQNAHLLTLFHRLCKLLFFRIRPIFVFDGEAPLLKRQTLAKRRQRKDNASNEAKKTHEKLLRTFLKRQAI--KAALSGNKQRFIQTYYLLS---YPCSSEEEEERAWEERMTQKQRLQEEFFANPSSVDIESEEFISLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEDSNDFSQYQLSGLLKKNNLNKCIDNVRKELNQQYSGEVQAQFEAE--GGFLKEVETRRLVSEDNSHYILI 510          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Xenopus
Match: amigo1 (adhesion molecule with Ig-like domain 1 [Source:Xenbase;Acc:XB-GENE-922133])

HSP 1 Score: 169.474 bits (428), Expect = 2.473e-42
Identity = 111/311 (35.69%), Postives = 169/311 (54.34%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLL--EKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLD--------FAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +WQ    E +E    NLY +   +++Q       AA+++ +   E+++LL++FGIPYI +P EAEAQCA L+  + T+GTIT+DSDIWLFG   VYK+ F+++     Y    I   LGL +  +I +A L GSDYT G+  +G V AMEIL EF    ++      L  FK W   W++    +K + NP     +K+  R ++   FP+  V +AY +P+VDES+  F W RP ++Q+ +        F   + GW R K  E+L  V K   +++   +   +D F   +  E +  K   S+RLR A
Sbjct:  950 EWQDISVEELESLENNLYVQQTSLQAQRQQQERIAATVTGQMCLESQELLRLFGIPYIVAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYKNFFTQNKHVEYYQYADIHNQLGLDRSKLINLAYLLGSDYTEGIPTVGYVSAMEILNEFPAQGLES-----LLQFKEW---WTEAQKDKKMRPNPHDTKVKKKLRRLEIHQGFPNPAVANAYLKPVVDESKAAFCWGRPDLEQIREYPLLFINIFNTCRFGWYRSKTDEVLLPVLKQINAQQTQLR---IDSFFRLEQHEAIGLK---SQRLRRA 1246          

HSP 2 Score: 103.99 bits (258), Expect = 6.020e-22
Identity = 71/260 (27.31%), Postives = 135/260 (51.92%), Query Frame = 1
Query:  193 MSIWLNQALRSGIDSP-----NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSN--FSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMI 942
            +SIWLNQA++   D       N HL  LF R+CKLLF++I+P+FVFDG +P LK++T+  RR+ +     +++K    ++   +K++ +  + ++S NK      + L     Y   S  + E  +    T    L    F++ + V++ES  F S+P EV+HEI+   +   K +R  +       + +  ++FS  Q+  LL +N L + ++++R  +N + +  V      +        + TR+++S ++ + ++I
Sbjct:  479 ISIWLNQAVKGARDRQGNAIQNAHLLTLFHRLCKLLFFRIRPIFVFDGEAPLLKRQTLAKRRQRKDNASNEAKKTHEKLLRTFLKRQAI--KAALSGNKQRFIQTYYLLS---YPCSSEEEEERAWEERMTQKQRLQEEFFANPSSVDIESEEFISLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEDSNDFSQYQLSGLLKKNNLNKCIDNVRKELNQQYSGEVQAQFEAE--GGFLKEVETRRLVSEDNSHYILI 726          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Xenopus
Match: amigo1 (adhesion molecule with Ig-like domain 1 [Source:Xenbase;Acc:XB-GENE-922133])

HSP 1 Score: 166.777 bits (421), Expect = 1.409e-41
Identity = 93/243 (38.27%), Postives = 141/243 (58.02%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLL--EKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDF 2460
            +WQ    E +E    NLY +   +++Q       AA+++ +   E+++LL++FGIPYI +P EAEAQCA L+  + T+GTIT+DSDIWLFG   VYK+ F+++     Y    I   LGL +  +I +A L GSDYT G+  +G V AMEIL EF          + L  FK W   W++    +K + NP     +K+  R ++   FP+  V +AY +P+VDES+  F W RP ++Q+ ++
Sbjct:  814 EWQDISVEELESLENNLYVQQTSLQAQRQQQERIAATVTGQMCLESQELLRLFGIPYIVAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYKNFFTQNKHVEYYQYADIHNQLGLDRSKLINLAYLLGSDYTEGIPTVGYVSAMEILNEFP-----AQGLESLLQFKEW---WTEAQKDKKMRPNPHDTKVKKKLRRLEIHQGFPNPAVANAYLKPVVDESKAAFCWGRPDLEQIREY 1048          

HSP 2 Score: 159.073 bits (401), Expect = 3.886e-39
Identity = 95/305 (31.15%), Postives = 166/305 (54.43%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSP-----NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKS--------------EADDLFQLP---ENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMI 942
            MGVQGLW +L  TGR I+  +LEGK+LAID+SIWLNQA++   D       N HL  LF R+CKLLF++I+P+FVFDG +P LK++T+  RR+ +     +++K    ++   +K++ +  + ++S NK               E DDL+ LP   +NE Y +    +   E  ++         F++ + V++ES  F S+P EV+HEI+   +   K +R  +       + +  ++FS  Q+  LL +N L + ++++R  +N + +  V      +        + TR+++S ++ + ++I
Sbjct:    1 MGVQGLWKLLECTGRPINAETLEGKILAIDISIWLNQAVKGARDRQGNAIQNAHLLTLFHRLCKLLFFRIRPIFVFDGEAPLLKRQTLAKRRQRKDNASNEAKKTHEKLLRTFLKRQAI--KAALSGNKQSNDELPSFSKVRRKETDDLYILPPLEDNEKYSSEEEEERAWEERMTQKQRLQEEFFANPSSVDIESEEFISLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEDSNDFSQYQLSGLLKKNNLNKCIDNVRKELNQQYSGEVQAQFEAE--GGFLKEVETRRLVSEDNSHYILI 296          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Xenopus
Match: GEN1 (GEN1 Holliday junction 5' flap endonuclease [Source:HGNC Symbol;Acc:HGNC:26881])

HSP 1 Score: 84.3445 bits (207), Expect = 2.584e-16
Identity = 68/249 (27.31%), Postives = 119/249 (47.79%), Query Frame = 1
Query: 1879 QEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF--SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTP-GVYGIGPVIAMEILAEFSDPEIDQSHFKVL----------------ENFKMWHD-------KWSK-LLEKYKGNPE---RKRFLRFQLDHKFPDQRVVDAYNRPLVDESE--QPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNY 2529
            +E   +L+  GIP++++ GEAEA CA+L      +G IT D D++L+G   VY++     +D     Y +  I   LGL ++ ++ +A+L G DY P GV G+  V A++++   +   + QS   V                 + F   HD        W K   EK + + E   +++ LR +    FP ++V+D +   L+++++  +   W RPS+    +F   ++ W R    E L V+   Y
Sbjct:  115 KECLLMLECLGIPWVQAAGEAEAMCAYLNAHGYVDGCITNDGDVFLYGAQTVYRNFTMNVKDPHVDCYEVSKIKAQLGLDREELVGLAILLGCDYLPKGVPGVRKVQALKLIEMLNGESLLQSCTSVTGSAKDHERNGCKMCGSDRFCEPHDYDYRCPCDWHKEQREKQENSVEFNIKRKSLRCE---GFPYRQVIDEF---LINKNKLVKVLKWGRPSLQCFQNFTAERMDWPRHYSCEKLLVLLTYY 357          

HSP 2 Score: 67.3958 bits (163), Expect = 5.802e-11
Identity = 38/95 (40.00%), Postives = 54/95 (56.84%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQA-----LRSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR 372
            MGV  LW+IL    + + L SL GK LA+D+SIW+ +A     +   +  P  HL  LF RI  L    +K VFV +G +P +K ET+  R ++R
Sbjct:    1 MGVTDLWSILGPVKKHVPLESLAGKTLAVDLSIWVCEAQMVKQMIGVVHKP--HLRNLFFRISSLNLLGVKLVFVSEGEAPKIKAETMSKRNEMR 93          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Mouse
Match: Ercc5 (excision repair cross-complementing rodent repair deficiency, complementation group 5 [Source:MGI Symbol;Acc:MGI:103582])

HSP 1 Score: 188.348 bits (477), Expect = 1.835e-48
Identity = 109/283 (38.52%), Postives = 169/283 (59.72%), Query Frame = 1
Query: 1717 IESEEINKFSDADIAMILNDPIQWQE-NIEESIA---NLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWS--KLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKN 2526
            IE+ E ++ +D D   +   P +WQ+ N+EE  A   NL  E + +++Q       AAS++ + + E+++LL++FG+PYI++P EAEAQCA L+  + T+GTIT+DSDIWLFG   VYK+ F+++     Y     +  LGL ++ +I +A L GSDYT G+  +G V AMEIL EF    +D     +L+  + WH+  +  K+ E       +K+  + QL   FP+  V DAY RP+VD+S   F+W +P +D++ +F Q   GW R+K  E L  V K+
Sbjct:  707 IEAMEGHREADIDAEDM---PNEWQDINLEELDALESNLLAEQNSLKAQKQQQDRIAASVTGQMFLESQELLRLFGVPYIQAPMEAEAQCAMLDLTDQTSGTITDDSDIWLFGARHVYKNFFNKNKFVEYYQYVDFYSQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGRGLD----PLLKFSEWWHEAQNNKKVAENPYDTKVKKKLRKLQLTPGFPNPAVADAYLRPVVDDSRGSFLWGKPDVDKIREFCQRYFGWNRMKTDESLYPVLKH 982          

HSP 2 Score: 147.132 bits (370), Expect = 1.856e-35
Identity = 92/303 (30.36%), Postives = 162/303 (53.47%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDS-----PNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKR-KSVSHNKSEA-------DDLFQLP-----ENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLND--LPATINTRKILSRNDGYLMMI 942
            MGVQGLW +L  +G  +   +LEGKVLA+D+SIWLNQAL+   DS      N HL  LF R+CKLLF++I+P+FVFDG +P LKK+T+  RR+ +      S K    ++   +K++ ++   +S  H    +       DD++ LP     E    +     Q++          +    F +   +++ES  F S+P EV+HEI+   +   K +R  +       + +  ++FS  Q++ LL +N L Q +E+++  MN +++    G +++Q  ++      + +R+++S +  + ++I
Sbjct:    1 MGVQGLWKLLECSGHRVSPEALEGKVLAVDISIWLNQALKGVRDSHGNVIENAHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLAKRRQRKDSASIDSRKTTEKLLKTFLKRQALKTAFRSSRHEAPPSLTQVQRQDDIYVLPPLPEEEKHSSEEEDEKQWQARMDQKQALQEEF--FHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEESNDFSQYQLKGLLKKNYLNQHIENVQKEMNQQHS----GQIQRQYQDEGGFLKEVESRRVVSEDTSHYILI 292          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Mouse
Match: Fen1 (flap structure specific endonuclease 1 [Source:MGI Symbol;Acc:MGI:102779])

HSP 1 Score: 86.6557 bits (213), Expect = 1.872e-17
Identity = 51/169 (30.18%), Postives = 88/169 (52.07%), Query Frame = 1
Query: 1813 ANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE-----IDQSHFKVLENFKMWHDKWSKLL 2295
            A + +E  K   +   +++++  E K LL + GIPY+++P EAEA CA L K        TED D   FG  ++ +H+    ++    + + L  + + LGL+Q+  + + +L GSDY   + GIGP  A++++ +    E     +D S + V EN   W  K ++ L
Sbjct:  117 AGMEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPSKYPVPEN---WLHKEAQQL 282          

HSP 2 Score: 51.2174 bits (121), Expect = 3.736e-6
Identity = 57/213 (26.76%), Postives = 92/213 (43.19%), Query Frame = 1
Query:  103 MGVQGLWNILH----STGRDIDLSSLEGKVLAIDMSIWLNQ---ALRSGID-------SPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR-----QLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETE--------FGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQH 660
            MG+ GL  ++     S  R+ D+ S  G+ +AID S+ + Q   A+R G D           HL  +F R  +++   IKPV+VFDG  P LK   +  R + R     QL+Q +   ++  +      K+LV+  K   HN  E   L  L    Y D  S  +            +  +   +D L+  S +   +L +   K +P++  H
Sbjct:    1 MGIHGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGMEEEVEKF--TKRLVKVTK--QHN-DECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFH 208          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Mouse
Match: Fen1 (flap structure specific endonuclease 1 [Source:MGI Symbol;Acc:MGI:102779])

HSP 1 Score: 86.6557 bits (213), Expect = 1.872e-17
Identity = 51/169 (30.18%), Postives = 88/169 (52.07%), Query Frame = 1
Query: 1813 ANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE-----IDQSHFKVLENFKMWHDKWSKLL 2295
            A + +E  K   +   +++++  E K LL + GIPY+++P EAEA CA L K        TED D   FG  ++ +H+    ++    + + L  + + LGL+Q+  + + +L GSDY   + GIGP  A++++ +    E     +D S + V EN   W  K ++ L
Sbjct:  117 AGMEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPSKYPVPEN---WLHKEAQQL 282          

HSP 2 Score: 51.2174 bits (121), Expect = 3.736e-6
Identity = 57/213 (26.76%), Postives = 92/213 (43.19%), Query Frame = 1
Query:  103 MGVQGLWNILH----STGRDIDLSSLEGKVLAIDMSIWLNQ---ALRSGID-------SPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR-----QLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETE--------FGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQH 660
            MG+ GL  ++     S  R+ D+ S  G+ +AID S+ + Q   A+R G D           HL  +F R  +++   IKPV+VFDG  P LK   +  R + R     QL+Q +   ++  +      K+LV+  K   HN  E   L  L    Y D  S  +            +  +   +D L+  S +   +L +   K +P++  H
Sbjct:    1 MGIHGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGMEEEVEKF--TKRLVKVTK--QHN-DECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFH 208          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Mouse
Match: Fen1 (flap structure specific endonuclease 1 [Source:MGI Symbol;Acc:MGI:102779])

HSP 1 Score: 86.6557 bits (213), Expect = 1.872e-17
Identity = 51/169 (30.18%), Postives = 88/169 (52.07%), Query Frame = 1
Query: 1813 ANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE-----IDQSHFKVLENFKMWHDKWSKLL 2295
            A + +E  K   +   +++++  E K LL + GIPY+++P EAEA CA L K        TED D   FG  ++ +H+    ++    + + L  + + LGL+Q+  + + +L GSDY   + GIGP  A++++ +    E     +D S + V EN   W  K ++ L
Sbjct:  117 AGMEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPSKYPVPEN---WLHKEAQQL 282          

HSP 2 Score: 51.2174 bits (121), Expect = 3.736e-6
Identity = 57/213 (26.76%), Postives = 92/213 (43.19%), Query Frame = 1
Query:  103 MGVQGLWNILH----STGRDIDLSSLEGKVLAIDMSIWLNQ---ALRSGID-------SPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR-----QLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETE--------FGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQH 660
            MG+ GL  ++     S  R+ D+ S  G+ +AID S+ + Q   A+R G D           HL  +F R  +++   IKPV+VFDG  P LK   +  R + R     QL+Q +   ++  +      K+LV+  K   HN  E   L  L    Y D  S  +            +  +   +D L+  S +   +L +   K +P++  H
Sbjct:    1 MGIHGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGMEEEVEKF--TKRLVKVTK--QHN-DECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFH 208          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Mouse
Match: Fen1 (flap structure specific endonuclease 1 [Source:MGI Symbol;Acc:MGI:102779])

HSP 1 Score: 86.6557 bits (213), Expect = 1.872e-17
Identity = 51/169 (30.18%), Postives = 88/169 (52.07%), Query Frame = 1
Query: 1813 ANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE-----IDQSHFKVLENFKMWHDKWSKLL 2295
            A + +E  K   +   +++++  E K LL + GIPY+++P EAEA CA L K        TED D   FG  ++ +H+    ++    + + L  + + LGL+Q+  + + +L GSDY   + GIGP  A++++ +    E     +D S + V EN   W  K ++ L
Sbjct:  117 AGMEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPSKYPVPEN---WLHKEAQQL 282          

HSP 2 Score: 51.2174 bits (121), Expect = 3.736e-6
Identity = 57/213 (26.76%), Postives = 92/213 (43.19%), Query Frame = 1
Query:  103 MGVQGLWNILH----STGRDIDLSSLEGKVLAIDMSIWLNQ---ALRSGID-------SPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR-----QLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETE--------FGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQH 660
            MG+ GL  ++     S  R+ D+ S  G+ +AID S+ + Q   A+R G D           HL  +F R  +++   IKPV+VFDG  P LK   +  R + R     QL+Q +   ++  +      K+LV+  K   HN  E   L  L    Y D  S  +            +  +   +D L+  S +   +L +   K +P++  H
Sbjct:    1 MGIHGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGMEEEVEKF--TKRLVKVTK--QHN-DECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFH 208          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. UniProt/SwissProt
Match: sp|P35689|ERCC5_MOUSE (DNA repair protein complementing XP-G cells homolog OS=Mus musculus OX=10090 GN=Ercc5 PE=1 SV=4)

HSP 1 Score: 187.193 bits (474), Expect = 3.086e-47
Identity = 109/283 (38.52%), Postives = 168/283 (59.36%), Query Frame = 1
Query: 1717 IESEEINKFSDADIAMILNDPIQWQE-NIEESIA---NLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWS--KLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKN 2526
            IE+ E ++ +D D   +   P +WQ+ N+EE  A   NL  E + +++Q       AAS++ + + E+++LL++FG+PYI++P EAEAQCA L+  + T+GTIT+DSDIWLFG   VYK+ F+++     Y     +  LGL ++ +I +A L GSDYT G+  +G V AMEIL EF    +D     +L+  + WH+  +  K+ E       +K+  + QL   FP+  V DAY RP+VD+S   F+W +P +D++  F Q   GW R+K  E L  V K+
Sbjct:  707 IEAMEGHREADIDAEDM---PNEWQDINLEELDALESNLLAEQNSLKAQKQQQDRIAASVTGQMFLESQELLRLFGVPYIQAPMEAEAQCAMLDLTDQTSGTITDDSDIWLFGARHVYKNFFNKNKFVEYYQYVDFYSQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGRGLD----PLLKFSEWWHEAQNNKKVAENPYDTKVKKKLRKLQLTPGFPNPAVADAYLRPVVDDSRGSFLWGKPDVDKISTFCQRYFGWNRMKTDESLYPVLKH 982          

HSP 2 Score: 147.132 bits (370), Expect = 1.222e-34
Identity = 92/303 (30.36%), Postives = 162/303 (53.47%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDS-----PNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKR-KSVSHNKSEA-------DDLFQLP-----ENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLND--LPATINTRKILSRNDGYLMMI 942
            MGVQGLW +L  +G  +   +LEGKVLA+D+SIWLNQAL+   DS      N HL  LF R+CKLLF++I+P+FVFDG +P LKK+T+  RR+ +      S K    ++   +K++ ++   +S  H    +       DD++ LP     E    +     Q++          +    F +   +++ES  F S+P EV+HEI+   +   K +R  +       + +  ++FS  Q++ LL +N L Q +E+++  MN +++    G +++Q  ++      + +R+++S +  + ++I
Sbjct:    1 MGVQGLWKLLECSGHRVSPEALEGKVLAVDISIWLNQALKGVRDSHGNVIENAHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLAKRRQRKDSASIDSRKTTEKLLKTFLKRQALKTAFRSSRHEAPPSLTQVQRQDDIYVLPPLPEEEKHSSEEEDEKQWQARMDQKQALQEEF--FHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEESNDFSQYQLKGLLKKNYLNQHIENVQKEMNQQHS----GQIQRQYQDEGGFLKEVESRRVVSEDTSHYILI 292          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. UniProt/SwissProt
Match: sp|P14629|ERCC5_XENLA (DNA repair protein complementing XP-G cells homolog OS=Xenopus laevis OX=8355 GN=ercc5 PE=2 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 9.781e-45
Identity = 98/236 (41.53%), Postives = 140/236 (59.32%), Query Frame = 1
Query: 1852 AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLL--EKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKK 2541
            AA+++ +   E+++LL++FGIPYI +P EAEAQCA L+  + T+GTIT+DSDIWLFG   VYK+ FS++     Y    I   LGL +  +I +A L GSDYT G+  +G V AMEIL EF          + L  FK W   WS+    +K + NP     +K+     L   FP+  V  AY +P+VDES+  F W RP ++Q+ +F +S+ GW RLK  E+L  V K   +++
Sbjct:  794 AATVTGQMCLESQELLQLFGIPYIVAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYKNFFSQNKHVEYYQYADIHNQLGLDRSKLINLAYLLGSDYTEGIPTVGYVSAMEILNEFPG-----QGLEPLVKFKEW---WSEAQKDKKMRPNPNDTKVKKKLRLLDLQQSFPNPAVASAYLKPVVDESKSAFSWGRPDLEQIREFCESRFGWYRLKTDEVLLPVLKQLNAQQ 1021          

HSP 2 Score: 152.14 bits (383), Expect = 3.631e-36
Identity = 93/305 (30.49%), Postives = 159/305 (52.13%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSP-----NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDL---FQLPENEYYDTISMNQFETEFGISDTALDYLSNFSSMNE--------------VNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMI 942
            MGVQGLW +L  +GR I+  +LEGK+LA+D+SIWLNQA++   D       N HL  LF R+CKLLF++I+P+FVFDG +P LK++T+  RR+        + K    ++   +K++ +  + ++S NK   ++L    Q+P  E  D   +   E     S    +       MN+              V++ES  FKS+P EV+HEI+   +   K +R  +       + +   +FS  Q++ LL +N L + ++++R  +N + +  V      +        + TR+++S +D + ++I
Sbjct:    1 MGVQGLWKLLECSGRPINPGTLEGKILAVDISIWLNQAVKGARDRQGNAIQNAHLLTLFHRLCKLLFFRIRPIFVFDGEAPLLKRQTLAKRRQRTDKASNDARKTNEKLLRTFLKRQAI--KAALSGNKQSNEELPSFSQVPRKETEDLYILPPLEDNENNSSEEEEEREWEERMNQKQRLQEDFFANPSSVDIESEEFKSLPPEVKHEILTDMKDFTKRRRTLFEA-----MPEDSSDFSQYQLKGLLKKNDLNKCIDNVRKELNQQYSGEVQAQFESE--GGFLKEVETRRLVSEDDSHYILI 296          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. UniProt/SwissProt
Match: sp|P28715|ERCC5_HUMAN (DNA repair protein complementing XP-G cells OS=Homo sapiens OX=9606 GN=ERCC5 PE=1 SV=3)

HSP 1 Score: 177.563 bits (449), Expect = 3.560e-44
Identity = 106/301 (35.22%), Postives = 170/301 (56.48%), Query Frame = 1
Query: 1783 QWQ----ENIEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +WQ    E +E   +NL  + + +++Q       AA+++ + + E+++LL++FGIPYI++P EAEAQCA L+  + T+GTIT+DSDIWLFG   VY++ F+++     Y        LGL ++ +I +A L GSDYT G+  +G V AMEIL EF    ++     +L+  + WH+       K + NP     +K+    QL   FP+  V +AY +P+VD+S+  F+W +P +D++ +F Q   GW R K  E L  V K   +++   +   +D F      E  ++KR  S+RL  A
Sbjct:  727 EWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLE----PLLKFSEWWHEAQKN--PKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLR---IDSFFRLAQQEKEDAKRIKSQRLNRA 1018          

HSP 2 Score: 156.377 bits (394), Expect = 1.466e-37
Identity = 101/314 (32.17%), Postives = 167/314 (53.18%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLV---------EKRKSVSHNKSEADDLFQLP------------ENEYYDTISMNQ---FETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLND--LPATINTRKILSRNDGYLMMI 942
            MGVQGLW +L  +GR +   +LEGK+LA+D+SIWLNQAL     R G    N HL  LF R+CKLLF++I+P+FVFDG +P LKK+T++ RR+ + L    S K    ++   +K++ +         E   S++  + E +DL+ LP            E+E      MNQ    + EF            F +   +++ES  F S+P EV+HEI+   +   K +R  +       + +  D+FS  Q++ LL +N L Q +E ++  MN +++    G +R+Q  ++      + +R+++S +  + ++I
Sbjct:    1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRE-NDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEF------------FHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEA-----MPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHS----GHIRRQYEDEGGFLKEVESRRVVSEDTSHYILI 292          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. UniProt/SwissProt
Match: sp|P07276|RAD2_YEAST (DNA repair protein RAD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RAD2 PE=1 SV=2)

HSP 1 Score: 166.777 bits (421), Expect = 5.929e-41
Identity = 93/237 (39.24%), Postives = 136/237 (57.38%), Query Frame = 1
Query: 1819 LYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWH-----DKWSKLLEKYKGNPERKRFLRFQ--LDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEML 2508
            L+++  K +  +  ++    +E ++LL  FGIPYI +P EAEAQCA L + NL +G IT+DSD++LFGG  +YK++F        Y  + I K+LGL +  MI +A L GSDYT G+ G+GPV ++E++AEF +          L+NFK W+     DK  +  E       RK+ +  +  LD  FP   V DAY RP VD    PF+W  P +D L  F ++++GW   K  E+L
Sbjct:  753 LFEQQMKDKRDSDEVTMDMIKEVQELLSRFGIPYITAPMEAEAQCAELLQLNLVDGIITDDSDVFLFGGTKIYKNMFHEKNYVEFYDAESILKLLGLDRKNMIELAQLLGSDYTNGLKGMGPVSSIEVIAEFGN----------LKNFKDWYNNGQFDKRKQETENKFEKDLRKKLVNNEIILDDDFPSVMVYDAYMRPEVDHDTTPFVWGVPDLDMLRSFMKTQLGWPHEKSDEIL 979          

HSP 2 Score: 112.464 bits (280), Expect = 7.054e-24
Identity = 77/251 (30.68%), Postives = 127/251 (50.60%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRS-----GIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEY-YDTISMNQFETEFGISDTALDYLSNFSSMNEVNLE----------SGSFKSMPLEVQHEIIR--YIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKV 801
            MGV   W+I   T R + L SLE K +A+D SIW+ Q L++     G    N H+   FRRICKLL++ I+PVFVFDG  P LK+ETI  R++ RQ K+E ++     ++ L ++    +  K+ + +   +  +F+ P++E+    I   +++ E    ++   +    +S+N   LE          S  F+ +P   Q+ I+    +    R GY+  Q   +  +  +FS  QI  +  RN   QK+
Sbjct:    1 MGVHSFWDIAGPTARPVRLESLEDKRMAVDASIWIYQFLKAVRDQEGNAVKNSHITGFFRRICKLLYFGIRPVFVFDGGVPVLKRETIRQRKERRQGKRESAKSTARKLLALQLQNGSNDNVKNSTPSSGSSVQIFK-PQDEWDLPDIPGFKYDKEDARVNSNKTFEKLMNSINGDGLEDIDLDTINPASAEFEELPKATQYLILSSLRLKSRLRMGYSKEQLETIFPNSMDFSRFQIDMVKRRNFFTQKL 250          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. UniProt/SwissProt
Match: sp|Q9ATY5|UVH3_ARATH (DNA repair protein UVH3 OS=Arabidopsis thaliana OX=3702 GN=UVH3 PE=2 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 8.474e-39
Identity = 105/296 (35.47%), Postives = 150/296 (50.68%), Query Frame = 1
Query: 1777 PIQWQE-NIEESI-------ANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDK-------------WSKLLEKYKGNPERKRFLR-------------FQLDHK-----------FPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNY 2529
            P+++ E NIEE I        +L  E  K+E  A S+S   + E ++LL+IFGIPYI +P EAEAQCAF+E+ NL +G +T+DSD++LFG   VYK++F        Y +K I K LGLS+D +I +A+L GSDYT G+ GIG V A+E++  F  PE D      L+ F+ W +               SK+ ++   + + K  +              F   H+           FP + V+ AY  P VD S + F W +P +  L      K  W   K  E+L  V K Y
Sbjct:  885 PVEFSEANIEEEIRVLDQEFVSLGDEQRKLERNAESVSSEMFAECQELLQIFGIPYIIAPMEAEAQCAFMEQSNLVDGIVTDDSDVFLFGARSVYKNIFDDRKYVETYFMKDIEKELGLSRDKIIRMAMLLGSDYTEGISGIGIVNAIEVVTAF--PEEDG-----LQKFREWVESPDPTILGKTDAKTGSKVKKRGSASVDNKGIISGASTDDTEEIKQIFMDQHRKVSKNWHIPLTFPSEAVISAYLNPQVDLSTEKFSWGKPDLSVLRKLCWEKFNWNGKKTDELLLPVLKEY 1173          

HSP 2 Score: 112.464 bits (280), Expect = 9.120e-24
Identity = 59/151 (39.07%), Postives = 89/151 (58.94%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSP-----NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSN-IIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMN 537
            MGVQGLW +L   GR + + +L  K LAID SIW+ Q +++  D       N HL   FRRICKLLF + KP+FVFDG +P+LK+ T+I RR+ R+  Q K  K     +++ L   +L E+ K + + + + DD  ++ +    D++  N
Sbjct:    1 MGVQGLWELLAPVGRRVSVETLANKRLAIDASIWMVQFIKAMRDEKGDMVQNAHLIGFFRRICKLLFLRTKPIFVFDGATPALKRRTVIARRRQRENAQTKIRKTAEKLLLNRLKDIRLKEQAKDIKNQRLKQDDSDRVKKRVSSDSVEDN 151          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. TrEMBL
Match: K1R3C0 (DNA repair protein complementing XP-G cells-like protein OS=Crassostrea gigas OX=29159 GN=CGI_10015229 PE=4 SV=1)

HSP 1 Score: 227.639 bits (579), Expect = 2.399e-58
Identity = 130/315 (41.27%), Postives = 192/315 (60.95%), Query Frame = 1
Query: 1717 IESEEINKFSDADIAMILNDPIQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLATRQ 2649
            I SE  N        ++ ND  +  E++E     L +E  + E  A S+S++ Y EA+DLLK+FG+P++ SP EAEAQCA+L+  NLTNGTIT+DSDIWLFGG  VYK+ F++D +   +    I   LGL++++ I +ALL GSDYT G+ G+GPV AMEIL+EF  P  D S    L+ FK W   W +  +K+K NP+    R +  + ++   FPD R+VDAY +P VD+S++ F W+ P +D L ++A+ K+GW ++K  E+L  V +    K+   Q  I  YF   + +  M  K+  S RL+ A ++
Sbjct:  585 ISSESPNDLVKQFTELVENDVDRVYEDLELETRALQQERGRQERLATSLSDQMYLEAQDLLKLFGVPFVLSPTEAEAQCAWLDSANLTNGTITDDSDIWLFGGRRVYKNFFNQDRTVELFMNDSIQSQLGLNREIFINMALLCGSDYTDGIPGVGPVTAMEILSEF--PAADLS---ALQAFKSW---WEE-TQKHKRNPKISKIRSKLRQLEVSEGFPDHRIVDAYLKPTVDDSKEAFSWALPDLDLLREYAKEKLGWAQVKTDEVLLPVLQKL--KETQVQTRINSYF---QPENFMEPKKLKSVRLKRALKK 885          

HSP 2 Score: 181.03 bits (458), Expect = 4.853e-43
Identity = 109/306 (35.62%), Postives = 175/306 (57.19%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQA---LRSGIDSP--NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMK----KKLVEKRKSV---------------SHNKSEADDLFQLP--ENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMI 942
            MGV GLW++L  TGR + L SLEGKVLA+D+SIWL+QA   +R+   SP  N HL +LF R+CKLL+YKIKPVFVFDG  P LKK+T+ +RR+ + + + + +K    I+D L+K    K++++K  +                S   ++  DLFQLP    E+     +  +E     +  A  +   + ++++V+++S  FKS+P EVQHEI+  + KE+R       +  L K  ++FSS Q+ +LL +N L  K+E++R  M  + +  +   L +  +      I  ++ILS +  + ++I
Sbjct:    1 MGVHGLWHLLQPTGRPVSLQSLEGKVLAVDVSIWLHQAVKGMRNKDGSPISNAHLHVLFTRVCKLLYYKIKPVFVFDGRVPELKKQTMASRREKKMIAEVEGDKASKKILDNLLKSHALKEVMKKGHASTDSSSSVSQPSTSSHSQQSAQKPDLFQLPPLPEEFARAQEIQPWEEP---TTNATIFEDEYQNLDDVDIDSAEFKSLPAEVQHEILSEL-KERRKRLTRYSNLKLPKDSNDFSSFQMAKLLKQNDLSNKLEEVRMKMTKQISGEITQDLGEHAVG---TEIQAQRILSDDSSHFILI 299          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. TrEMBL
Match: A0A443SNK8 (Uncharacterized protein OS=Leptotrombidium deliense OX=299467 GN=B4U80_04585 PE=4 SV=1)

HSP 1 Score: 224.557 bits (571), Expect = 1.545e-57
Identity = 133/312 (42.63%), Postives = 177/312 (56.73%), Query Frame = 1
Query: 1789 QENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKK-----------------LFC-----------QKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            +E++   +  + +E  K E  A ++SE+   E KDLLK+FGIPY+ SP EAEAQCA LE   LT+GTIT+DSDIWLFGG  VYK+ F++      YS K I +   L++  MIC+ALL+GSDYT GV G+G V A+EIL+EF++P      F+ L +FK W  +  +  +K  GN  R++F++  LD  FP++ V DAY  P VDE+ + F W  P +D L DFA+ K GW   KV E L  V K    KK                 L C           QK I DYF   K +   N + +PSKRL  A
Sbjct:  566 REDLSRDLYLMEREVGKHERHANTVSEQMITECKDLLKLFGIPYVVSPMEAEAQCAALEIMGLTSGTITDDSDIWLFGGKTVYKNFFTQSKLVEKYSSKDIEEHFKLNRASMICLALLTGSDYTVGVDGVGAVKAVEILSEFNEP-----GFESLLSFKKWWTEKQRNRDKSPGNKTREKFIKLTLDEGFPNRVVFDAYWTPRVDETPEDFSWGSPDLDLLRDFARRKFGWTLSKVDETLLPVIKRLNEKKVTDTLLTFQLHSLATLSLICCLILMFLFPKVQKRIDDYF---KCEVRRNGQIAPSKRLMSA 869          

HSP 2 Score: 92.4337 bits (228), Expect = 2.638e-15
Identity = 74/196 (37.76%), Postives = 109/196 (55.61%), Query Frame = 1
Query:  241 NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINR--RKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEA--------------DDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSR 780
            N HL  L++RI KLLF KIKPVFVFDG +P LK++T+I R  RK + L+  KSEK   N +   +  +L +K     +NKSE               DD+F LP+    DT      E ++     A   LS + +++ +++ES SFKS+P E++HE + Y+ KEKR G+      F  ++ D FS+ Q+  LL +
Sbjct:   16 NAHLLGLYQRILKLLFCKIKPVFVFDGGTPYLKRQTLIARNSRKFQSLR--KSEKTAENALRTYLSTQL-KKPLDNDNNKSEPNISLESTRRILLDNDDMFTLPDFVTEDTEEEEITEDDYNAEVDA--KLSEYQNVDNIDIESDSFKSLPPEMRHEFLSYL-KEKRKGWARLH-EFPTENND-FSAYQMNNLLRK 203          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. TrEMBL
Match: A0A1Z5KVX8 (DNA-repair protein xp-G (Fragment) OS=Ornithodoros moubata OX=6938 PE=4 SV=1)

HSP 1 Score: 222.246 bits (565), Expect = 6.288e-57
Identity = 117/279 (41.94%), Postives = 163/279 (58.42%), Query Frame = 1
Query: 1798 IEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLR 2634
            +EES      E +++E Q   +S++  QE ++LL++ G+PY+ SP EAEAQCA LE+  LT GT+T+DSD+WLFGG  VYKH F R+     ++   I +  GL +  MI  ALLSGSDYT G+ G+GPV AMEI++EF   +        L  FK W +K +KL +   G+  R   +RF+L  +FP + VVDAY  P  D S + F W  P +D L  F   K+GW + K+  +L  V K    K+  CQ  I  YF+   V+ +   +  PSKRLR
Sbjct:  574 LEESRRRTETEANRLELQGTQLSQQMAQECQELLRLLGMPYLVSPEEAEAQCALLEQLGLTQGTVTDDSDVWLFGGTSVYKHFFQREKLVEHFAYDDILRHFGLDRQKMIAFALLSGSDYTTGIRGVGPVSAMEIISEFGAADA----ISTLSAFKEWLEK-AKLEQTSPGSKTRSHLVRFELTSEFPSRVVVDAYLNPATDSSTENFTWGTPDLDALRSFGLQKLGWTQDKMDSLLLPVLKRLQEKQ--CQSRIDSYFS---VETIKREQLFPSKRLR 842          

HSP 2 Score: 146.362 bits (368), Expect = 4.061e-32
Identity = 90/274 (32.85%), Postives = 145/274 (52.92%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQA---LRSGIDSP--NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINR--RKLRQLKQEKSEKIKSNII--------------------DLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQN 843
            MGVQGLW +L   G+ + L +LE KVL +D+S+WL+QA   +R G   P  N HL +L +R+CKLLFY+IKPVFVFDG  P LK++T+  R  R+   L++ + ++++  +I                      L K      RK+ S  +    D+F+LP          +  E E G S T +D        + ++++S  F  +P  ++H+I+  + + +RYG    Q   L K  + FSS Q+ RLL +  +QQ++E+ R  +++  +Q 
Sbjct:    1 MGVQGLWQVLEPVGKPVALETLENKVLGVDVSLWLHQAVKGMRDGRGEPVSNAHLVVLLQRVCKLLFYRIKPVFVFDGGVPQLKRQTLAGRQQRQAAALEEAQRQRVRKALIAHAQQRLRKTRGPNPPGPSSTTLQKSPQKSPRKATSAVQP---DMFELPPLPAPMATFDSDEEDEDG-SSTRVDV------PDTLDVDSEDFSQLPANIRHDILVDLHERQRYGSRRNQ---LPKEAESFSSYQMSRLLKKRNIQQRLEEARRDLSHFRSQQ 261          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. TrEMBL
Match: A0A2P6KGL4 (Ercc5 OS=Nephila clavipes OX=2585209 GN=NCL1_40921 PE=4 SV=1)

HSP 1 Score: 223.016 bits (567), Expect = 7.449e-57
Identity = 124/302 (41.06%), Postives = 174/302 (57.62%), Query Frame = 1
Query: 1759 AMILNDPIQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPE---RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDS--KVDELMNSKRSPSKRLRLATRQ 2649
            A I    +Q+QE++E + A L  +  K + Q  ++ E   +E K+LL++FG+PYI SP EAEAQCAF +  NLT+GTIT+DSD+WLFGG  VYK+ F++      Y    IF   GLS+  +I  A+L+GSDYT G+ G+GPV A EIL+EF D        + L  FK W   W++   K+   PE   R + ++  L  KFPD+R+ DAY  P +D+S + F W RP +D L D+ + + GW + KV E L  V K    +    Q  I ++FT S  K   L  SKR  S   +L + Q
Sbjct:  601 AEIAQKNLQFQEDLESATALLEADKAKQDRQNRTVQEHMVEECKELLQLFGVPYIVSPTEAEAQCAFYDYSNLTHGTITDDSDVWLFGGKRVYKNFFTQQKYVEFYKDHEIFTHFGLSRKKLINFAMLTGSDYTEGIEGVGPVTATEILSEFPD-----DGLEALYKFKEW---WAR-ANKHACPPENKVRAKLIKLVLGEKFPDERITDAYLNPTIDDSTEKFTWGRPDLDALRDYTRERFGWNKNKVDEALLPVIKKLSERD--TQTHIDNFFTVSLKKQTNLFPSKRIMSALKKLTSPQ 891          

HSP 2 Score: 148.288 bits (373), Expect = 1.320e-32
Identity = 111/337 (32.94%), Postives = 171/337 (50.74%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDS-----PNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNII-DLLMKKKLV-------EKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFSS-----MNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQN---------VIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDIVDNLTKLKSEYLFKKHDQNIEQN 1032
            MGV GLW +L   G+ + L SLE K+ A+D+SIWLNQAL+   DS      N HL  LF R+CKLLFYKI+P+ VFDG  P LKK+TIINR + R   ++ S  I   I+ + L  + L        +K+  +   +   D++F LP       +  N  + E    D+     +NFS      ++++++ S  F ++P +V+ EI+  + KE R      Q   L +  ++FSS Q+Q LL + TL +K+E+++  M   N  +         VIG   K   +D    +  +KI+ ++ G        E    D  T L ++  F K  +NI+ N
Sbjct:    1 MGVLGLWQLLAPVGQPVALESLENKIFAVDISIWLNQALKGYRDSQGGAVANAHLLSLFSRLCKLLFYKIRPIIVFDGGFPELKKQTIINRHQRRAAIKQSSRDIGLKILTNYLASQNLASVGGESTQKKAIIRPKEKVRDEIFVLP------PLPDNSLKMEDDNIDSIDWKFTNFSKEDIKYLSKIDINSDDFNNLPPDVKQEILSTL-KESRKHRTWDQYEELPQDSNDFSSYQMQNLLKKRTLSRKLEEVQKDMRQINTADFVAQYTSDHVIGETNKIMSDDCSHYVLLKKIIQQSRG-------DENKNADGSTMLDTKNAFIKDLENIDVN 323          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. TrEMBL
Match: A0A3S3PD51 (DNA repair protein complementing XP-G cells-like protein OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_10177 PE=4 SV=1)

HSP 1 Score: 221.476 bits (563), Expect = 1.211e-56
Identity = 123/284 (43.31%), Postives = 179/284 (63.03%), Query Frame = 1
Query: 1792 ENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHD-KWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLA 2640
            ++++  +  + +E  + E  AA++S++   EA++LL++FGIP++ SP EAEAQCA LE   LT GTIT+DSDIWLFGG  VYK+ F++      Y+LK I K L ++++ M+C+A+L+GSDYT G+ GIG V A+EIL+EF    ++      LENFK W D K  K  +K  GN  R +F++F L+  FP++ V +AY  P VD++ + F W  P +D L  +A SK GW + KV E+L  V K    KK+  Q  I DYF   K +   + + S SKRL+ A
Sbjct:  544 QSVKRQLYEIEREVGRQERHAATVSDQMIIEAQELLRLFGIPFVRSPLEAEAQCAALENLELTEGTITDDSDIWLFGGKTVYKNFFNQSKYVEVYNLKDIEKDLKINRESMVCLAMLTGSDYTDGIEGIGAVTAVEILSEFKGEGLEP-----LENFKSWWDSKQGK--DKSPGNKTRAKFIKFSLEESFPNKVVFNAYMNPKVDDTLESFKWGVPDLDLLRHYAMSKFGWNKSKVDEVLLPVIKRLNEKKV--QMRISDYF---KCEARHSGQISTSKRLQSA 815          

HSP 2 Score: 168.703 bits (426), Expect = 3.377e-39
Identity = 111/307 (36.16%), Postives = 169/307 (55.05%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRS-----GIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKS----------EADDLFQLP----ENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTR----KILSRNDGYLMMIDPSE 954
            MGV+GLW +L   G+ I+L SLE KVLA+D SIWLNQ+++      G    N H++ LF RICKLLFYKIKP+FVFDG  P LKK+TI  R K R    E SEK     +   ++ ++     S S + +            D++F+LP    ENE+ +    +Q E+     +    +L N   +N+V++ S +FKS+P E++HEI+ ++ KE++ G+   + S L    +EFSS Q+ RLL +  LQQ +E     MN R        ++ ++L D  AT   R    +++S  +  ++  D S+
Sbjct:    1 MGVKGLWQLLEPIGKPINLESLENKVLAVDFSIWLNQSIKGIRDKHGHPVQNAHIKGLFNRICKLLFYKIKPIFVFDGGVPVLKKQTIATRHKRRLKSLEDSEKNAHKALKTFLRSQIKRSLGSESDDSNLKLLSTYRIHSNDNVFELPALENENEFNEV--DDQTESFCKQVNAQFSHLQN---LNQVDINSEAFKSLPPEIRHEILTHL-KEQKTGW--AKISALPSESNEFSSYQMSRLLHKRKLQQNIEVAEEEMNDR--------MQSEELFDFSATSGIRYESKRVMSDENTRIIYCDKSQ 291          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Cavefish
Match: ercc5 (ERCC excision repair 5, endonuclease [Source:NCBI gene;Acc:103045408])

HSP 1 Score: 175.252 bits (443), Expect = 2.261e-44
Identity = 95/260 (36.54%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 1780 IQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLE--KYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKK 2541
            +Q + +++   ++L+++  + +  AA+++ +  QE+++LL++FG+P++ +P EAEAQCA L++ + T+GTIT+DSD+WLFGG  VYK+ FS +     Y    I   LGL +  +I +A L GSDYT G+ G+G V  MEIL EF  P ++      L  F  W   W++  E  K + NP+    +K+    +L   FP+  V  AY +P VD+SE  F W R  +D + +F  S+ GW   K  E L  V K   +++
Sbjct:  766 VQLERDLQAEQSSLHEQQQQQQRSAATVTGQMCQESQELLRLFGVPFLVAPMEAEAQCAALDRTDQTHGTITDDSDVWLFGGRHVYKNFFSNNKYVEHYQYVDIQNQLGLDRTRLINLAYLLGSDYTEGIPGVGYVTGMEILNEFPGPGME-----PLTQFSKW---WTEAQENKKLRSNPKDTKVKKKLRNLKLHPGFPNPAVSQAYLQPAVDQSEGSFSWGRLQVDLIKEFCYSRFGWNSKKTEETLQPVLKQLNTQQ 1017          

HSP 2 Score: 146.747 bits (369), Expect = 1.748e-35
Identity = 100/312 (32.05%), Postives = 171/312 (54.81%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKR---------KSVSH-NKSEADDLFQL----PENEYYDTISMNQFETEFG--ISDTALDYLSNF-SSMNEVNLESGSFKSMPLEVQHEIIRYI---AKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDI 963
            MGV GLW +L STG+ I+  +LEGK+LA+D+SIWLNQA+     R G    N HL  LF R+CKLLF++I+PVFV+DG +P LKK+T+  RR+ ++    +S++    ++   +K++ ++            S+S   K E DDL+ L    P  E   + S  + + E G  + +  L    +F +  N V++ S  F  +  E++HEI++ +   +K +R  Y+        +S D FS  Q+  LL RN L Q++E +   M+ R+     G++ +Q       ++ T++++S +  + ++I  S+  +
Sbjct:    1 MGVHGLWKLLESTGKPINPETLEGKILAVDISIWLNQAVKGVRDRDGNSVQNAHLLTLFNRLCKLLFFRIRPVFVYDGDAPILKKQTLAIRRQRKEEITRESKQTNEKLLRTFLKRQAIKAALGDNSQAAIPSISSVRKDEEDDLYVLPALPPAEEKESSSSDEEVDREGGEEMPEAYLRLQEDFYADPNSVDINSEEFSLLSPEIKHEILKEMKEFSKRRRTMYHKPP----ERSKD-FSQYQLAGLLQRNKLNQRLEGVEKEMSQRS----CGAVEEQYSQGREHSVETQRLVSEDSSHYILIKGSQKTV 303          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Cavefish
Match: ercc5 (ERCC excision repair 5, endonuclease [Source:NCBI gene;Acc:103045408])

HSP 1 Score: 175.252 bits (443), Expect = 2.261e-44
Identity = 95/260 (36.54%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 1780 IQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLE--KYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKK 2541
            +Q + +++   ++L+++  + +  AA+++ +  QE+++LL++FG+P++ +P EAEAQCA L++ + T+GTIT+DSD+WLFGG  VYK+ FS +     Y    I   LGL +  +I +A L GSDYT G+ G+G V  MEIL EF  P ++      L  F  W   W++  E  K + NP+    +K+    +L   FP+  V  AY +P VD+SE  F W R  +D + +F  S+ GW   K  E L  V K   +++
Sbjct:  766 VQLERDLQAEQSSLHEQQQQQQRSAATVTGQMCQESQELLRLFGVPFLVAPMEAEAQCAALDRTDQTHGTITDDSDVWLFGGRHVYKNFFSNNKYVEHYQYVDIQNQLGLDRTRLINLAYLLGSDYTEGIPGVGYVTGMEILNEFPGPGME-----PLTQFSKW---WTEAQENKKLRSNPKDTKVKKKLRNLKLHPGFPNPAVSQAYLQPAVDQSEGSFSWGRLQVDLIKEFCYSRFGWNSKKTEETLQPVLKQLNTQQ 1017          

HSP 2 Score: 146.747 bits (369), Expect = 1.748e-35
Identity = 100/312 (32.05%), Postives = 171/312 (54.81%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKR---------KSVSH-NKSEADDLFQL----PENEYYDTISMNQFETEFG--ISDTALDYLSNF-SSMNEVNLESGSFKSMPLEVQHEIIRYI---AKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDI 963
            MGV GLW +L STG+ I+  +LEGK+LA+D+SIWLNQA+     R G    N HL  LF R+CKLLF++I+PVFV+DG +P LKK+T+  RR+ ++    +S++    ++   +K++ ++            S+S   K E DDL+ L    P  E   + S  + + E G  + +  L    +F +  N V++ S  F  +  E++HEI++ +   +K +R  Y+        +S D FS  Q+  LL RN L Q++E +   M+ R+     G++ +Q       ++ T++++S +  + ++I  S+  +
Sbjct:    1 MGVHGLWKLLESTGKPINPETLEGKILAVDISIWLNQAVKGVRDRDGNSVQNAHLLTLFNRLCKLLFFRIRPVFVYDGDAPILKKQTLAIRRQRKEEITRESKQTNEKLLRTFLKRQAIKAALGDNSQAAIPSISSVRKDEEDDLYVLPALPPAEEKESSSSDEEVDREGGEEMPEAYLRLQEDFYADPNSVDINSEEFSLLSPEIKHEILKEMKEFSKRRRTMYHKPP----ERSKD-FSQYQLAGLLQRNKLNQRLEGVEKEMSQRS----CGAVEEQYSQGREHSVETQRLVSEDSSHYILIKGSQKTV 303          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Cavefish
Match: ercc5 (ERCC excision repair 5, endonuclease [Source:NCBI gene;Acc:103045408])

HSP 1 Score: 175.252 bits (443), Expect = 2.261e-44
Identity = 95/260 (36.54%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 1780 IQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLE--KYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKK 2541
            +Q + +++   ++L+++  + +  AA+++ +  QE+++LL++FG+P++ +P EAEAQCA L++ + T+GTIT+DSD+WLFGG  VYK+ FS +     Y    I   LGL +  +I +A L GSDYT G+ G+G V  MEIL EF  P ++      L  F  W   W++  E  K + NP+    +K+    +L   FP+  V  AY +P VD+SE  F W R  +D + +F  S+ GW   K  E L  V K   +++
Sbjct:  766 VQLERDLQAEQSSLHEQQQQQQRSAATVTGQMCQESQELLRLFGVPFLVAPMEAEAQCAALDRTDQTHGTITDDSDVWLFGGRHVYKNFFSNNKYVEHYQYVDIQNQLGLDRTRLINLAYLLGSDYTEGIPGVGYVTGMEILNEFPGPGME-----PLTQFSKW---WTEAQENKKLRSNPKDTKVKKKLRNLKLHPGFPNPAVSQAYLQPAVDQSEGSFSWGRLQVDLIKEFCYSRFGWNSKKTEETLQPVLKQLNTQQ 1017          

HSP 2 Score: 146.747 bits (369), Expect = 1.748e-35
Identity = 100/312 (32.05%), Postives = 171/312 (54.81%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKR---------KSVSH-NKSEADDLFQL----PENEYYDTISMNQFETEFG--ISDTALDYLSNF-SSMNEVNLESGSFKSMPLEVQHEIIRYI---AKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDI 963
            MGV GLW +L STG+ I+  +LEGK+LA+D+SIWLNQA+     R G    N HL  LF R+CKLLF++I+PVFV+DG +P LKK+T+  RR+ ++    +S++    ++   +K++ ++            S+S   K E DDL+ L    P  E   + S  + + E G  + +  L    +F +  N V++ S  F  +  E++HEI++ +   +K +R  Y+        +S D FS  Q+  LL RN L Q++E +   M+ R+     G++ +Q       ++ T++++S +  + ++I  S+  +
Sbjct:    1 MGVHGLWKLLESTGKPINPETLEGKILAVDISIWLNQAVKGVRDRDGNSVQNAHLLTLFNRLCKLLFFRIRPVFVYDGDAPILKKQTLAIRRQRKEEITRESKQTNEKLLRTFLKRQAIKAALGDNSQAAIPSISSVRKDEEDDLYVLPALPPAEEKESSSSDEEVDREGGEEMPEAYLRLQEDFYADPNSVDINSEEFSLLSPEIKHEILKEMKEFSKRRRTMYHKPP----ERSKD-FSQYQLAGLLQRNKLNQRLEGVEKEMSQRS----CGAVEEQYSQGREHSVETQRLVSEDSSHYILIKGSQKTV 303          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000001764.2 (GEN1 Holliday junction 5' flap endonuclease [Source:NCBI gene;Acc:103041329])

HSP 1 Score: 81.2629 bits (199), Expect = 2.977e-15
Identity = 37/104 (35.58%), Postives = 63/104 (60.58%), Query Frame = 1
Query: 1879 QEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYK--HVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTP-GVYGIG 2181
            +E  ++L   G+P++ + GEAEA CAFL+ + L +G IT D D +L+G   VY+  ++ ++D     Y +  +   L L ++ ++ +A+L G DY P GV G+G
Sbjct:  121 RECAEMLDCLGVPWVAAAGEAEAMCAFLDAQGLVDGCITSDGDAFLYGAQTVYRNFNMNTKDPQIDCYKMSRVETELQLKRETLVGLAVLLGCDYIPKGVAGVG 224          

HSP 2 Score: 68.1662 bits (165), Expect = 3.025e-11
Identity = 41/106 (38.68%), Postives = 58/106 (54.72%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLN-----QALRSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRK--LRQLKQEKSEK 399
            MGV  LW+IL+     + L SL G+ LA+D+S+W+      QA+   +  P  HL  LF R+  LL   +K VFV +G +P +K ETI  R +   R+ K E   K
Sbjct:    1 MGVNELWSILNPVRESVPLYSLTGRTLAVDLSLWICEAQHVQAMMGRVTKP--HLRNLFFRVSSLLRMGVKLVFVMEGEAPKIKAETISKRTEGAFRRGKTESGPK 104          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Cavefish
Match: fen1 (flap structure-specific endonuclease 1 [Source:NCBI gene;Acc:111191587])

HSP 1 Score: 76.6406 bits (187), Expect = 2.112e-14
Identity = 70/269 (26.02%), Postives = 115/269 (42.75%), Query Frame = 1
Query: 1837 KIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE-----IDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDF--AQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKR 2613
            K   +   ++ ++  E K LL + G+PYIE+P EAEA CA L K      T TED D   FG  ++ +H+    ++    + +    I + + L+    I + +L G DY   + GIGP  A++++ +    E     IDQS     E++ ++ +     LE     PE                         +VD S     W+ P  D L+ F  A+ +   ER++     N   K   S++   Q  +  +FT   V   ++SKR
Sbjct:  125 KFSKRLVKVTRQHNDECKKLLSLMGVPYIEAPCEAEASCAALVKAGKVFATATEDMDGLTFGTNVLLRHLTASEAKKLPIQEFHFSRILQEMNLTHQQFIDLCILLGCDYCGTIKGIGPKRAIDLIRQHGSIEEILDNIDQSKHPAPEDW-LYKEARGLFLE-----PE-------------------------VVDCSTLELKWNEPDEDALIQFMCAEKQFSEERIR-----NGCKKIMKSRQGSTQGRLDTFFT---VTGSLSSKR 354          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009203.1 (pep scaffold:Pmarinus_7.0:GL485931:6413:9971:-1 gene:ENSPMAG00000008324.1 transcript:ENSPMAT00000009203.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 162.155 bits (409), Expect = 4.117e-45
Identity = 96/256 (37.50%), Postives = 142/256 (55.47%), Query Frame = 1
Query: 1885 AKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHD---KWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLAT 2643
            A++LL++FG+PY+ +PGEAEAQCA L+  + T+GTIT+DSDIWLFGG  VYK+ F+++     Y L  + + +GL +  ++ +A L GSDYT GV G+G V A+EIL EF  P I+      L   + W D   K  KL  +   +  ++R  +  L   FP+  V  AY  P        F W +P +  + +F QS+ GWE  K  E+L  V K   + +    +S +D F      E+ N +   SKR++ A 
Sbjct:    5 AQELLRMFGLPYMTAPGEAEAQCAALDLADRTHGTITDDSDIWLFGGRYVYKNFFNQNRHIDFYQLVDVQRHIGLDRTKLVNLAYLMGSDYTDGVAGVGGVTALEILNEFGGPGIEP-----LVTLRAWWDEAQKNRKLHARPVESKLKQRLRQLTLSEGFPNPAVARAYLEPATSTVAGGFSWGQPQLLSIAEFCQSRFGWEVKKTEELLRPVLKQLSATQ--QSQSRIDSFFPVVHSEVRNIR---SKRMKRAV 250          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003090.1 (pep scaffold:Pmarinus_7.0:GL486553:1283:3042:-1 gene:ENSPMAG00000002828.1 transcript:ENSPMAT00000003090.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 122.094 bits (305), Expect = 1.233e-32
Identity = 60/119 (50.42%), Postives = 80/119 (67.23%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPN-----VHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLV 444
            MGV+GLW +L STGR +DL SL+GKVLA D+SIW+NQA+R   D         HL  LF R+CKLLFY IKPVFVFDG +P LK+ T+  RR+ +   +  S +    ++ +L+KK+ V
Sbjct:    1 MGVKGLWTLLDSTGRPVDLESLKGKVLAADVSIWMNQAVRGVRDRHGNPIKAAHLVTLFHRVCKLLFYGIKPVFVFDGAAPLLKRRTLDVRRQRKGDAERDSSRAAERLMKVLLKKEAV 119          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009133.1 (pep scaffold:Pmarinus_7.0:GL481492:6824:20158:-1 gene:ENSPMAG00000008254.1 transcript:ENSPMAT00000009133.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.9518 bits (193), Expect = 9.971e-16
Identity = 40/111 (36.04%), Postives = 66/111 (59.46%), Query Frame = 1
Query: 1882 EAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFS--RDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTP-GVYGIGPVIAMEIL 2205
            +  +LL   G+P +++ GE EA CA L+   L +G  T+D D +L+G   VY+ + +  +D     Y +  I + LGL +D +I +A+L G DY P GV GIG  +A++++
Sbjct:   64 QCCELLSSLGLPCLQAAGEGEALCAALDAAGLVHGCFTDDGDAFLYGARTVYRGLAASDQDPHVERYCVDRIRRELGLDRDALIGLAVLLGCDYLPKGVKGIGKELALKLI 174          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009129.1 (pep scaffold:Pmarinus_7.0:GL481492:6818:20158:-1 gene:ENSPMAG00000008254.1 transcript:ENSPMAT00000009129.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.1814 bits (191), Expect = 1.779e-15
Identity = 40/111 (36.04%), Postives = 66/111 (59.46%), Query Frame = 1
Query: 1882 EAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFS--RDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTP-GVYGIGPVIAMEIL 2205
            +  +LL   G+P +++ GE EA CA L+   L +G  T+D D +L+G   VY+ + +  +D     Y +  I + LGL +D +I +A+L G DY P GV GIG  +A++++
Sbjct:   64 QCCELLSSLGLPCLQAAGEGEALCAALDAAGLVHGCFTDDGDAFLYGARTVYRGLAASDQDPHVERYCVDRIRRELGLDRDALIGLAVLLGCDYLPKGVKGIGKELALKLI 174          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009136.1 (pep scaffold:Pmarinus_7.0:GL481492:10436:20158:-1 gene:ENSPMAG00000008254.1 transcript:ENSPMAT00000009136.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.0258 bits (188), Expect = 2.636e-15
Identity = 40/118 (33.90%), Postives = 66/118 (55.93%), Query Frame = 1
Query: 1876 YQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFS-------RDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTP-GVYGIGPVIAMEIL 2205
            + +  +LL   G+P +++ GE EA CA L+   L +G  T+D D +L+G   VY+ + +        D     Y +  I + LGL +D +I +A+L G DY P GV GIG  +A++++
Sbjct:   70 HNQCCELLSSLGLPCLQAAGEGEALCAALDAAGLVHGCFTDDGDAFLYGARTVYRGLAASDQVPSYTDPHVERYCVDRIRRELGLDRDALIGLAVLLGCDYLPKGVKGIGKELALKLI 187          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Yeast
Match: RAD2 (Single-stranded DNA endonuclease; cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein [Source:SGD;Acc:S000003490])

HSP 1 Score: 166.777 bits (421), Expect = 8.539e-43
Identity = 93/237 (39.24%), Postives = 136/237 (57.38%), Query Frame = 1
Query: 1819 LYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWH-----DKWSKLLEKYKGNPERKRFLRFQ--LDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEML 2508
            L+++  K +  +  ++    +E ++LL  FGIPYI +P EAEAQCA L + NL +G IT+DSD++LFGG  +YK++F        Y  + I K+LGL +  MI +A L GSDYT G+ G+GPV ++E++AEF +          L+NFK W+     DK  +  E       RK+ +  +  LD  FP   V DAY RP VD    PF+W  P +D L  F ++++GW   K  E+L
Sbjct:  753 LFEQQMKDKRDSDEVTMDMIKEVQELLSRFGIPYITAPMEAEAQCAELLQLNLVDGIITDDSDVFLFGGTKIYKNMFHEKNYVEFYDAESILKLLGLDRKNMIELAQLLGSDYTNGLKGMGPVSSIEVIAEFGN----------LKNFKDWYNNGQFDKRKQETENKFEKDLRKKLVNNEIILDDDFPSVMVYDAYMRPEVDHDTTPFVWGVPDLDMLRSFMKTQLGWPHEKSDEIL 979          

HSP 2 Score: 112.464 bits (280), Expect = 1.016e-25
Identity = 77/251 (30.68%), Postives = 127/251 (50.60%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRS-----GIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEY-YDTISMNQFETEFGISDTALDYLSNFSSMNEVNLE----------SGSFKSMPLEVQHEIIR--YIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKV 801
            MGV   W+I   T R + L SLE K +A+D SIW+ Q L++     G    N H+   FRRICKLL++ I+PVFVFDG  P LK+ETI  R++ RQ K+E ++     ++ L ++    +  K+ + +   +  +F+ P++E+    I   +++ E    ++   +    +S+N   LE          S  F+ +P   Q+ I+    +    R GY+  Q   +  +  +FS  QI  +  RN   QK+
Sbjct:    1 MGVHSFWDIAGPTARPVRLESLEDKRMAVDASIWIYQFLKAVRDQEGNAVKNSHITGFFRRICKLLYFGIRPVFVFDGGVPVLKRETIRQRKERRQGKRESAKSTARKLLALQLQNGSNDNVKNSTPSSGSSVQIFK-PQDEWDLPDIPGFKYDKEDARVNSNKTFEKLMNSINGDGLEDIDLDTINPASAEFEELPKATQYLILSSLRLKSRLRMGYSKEQLETIFPNSMDFSRFQIDMVKRRNFFTQKL 250          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Yeast
Match: RAD27 (5' to 3' exonuclease, 5' flap endonuclease; required for Okazaki fragment processing and maturation, for long-patch base-excision repair and large loop repair (LLR), ribonucleotide excision repair; member of the S. pombe RAD2/FEN1 family; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000001596])

HSP 1 Score: 73.559 bits (179), Expect = 3.193e-14
Identity = 61/230 (26.52%), Postives = 112/230 (48.70%), Query Frame = 1
Query: 1780 IQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHV-FSRDFSARAYSL--KHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEI---------LAEFSDP-EIDQSHFKVLENFKMWHDKWSKLL----EKYKGN--------PERKRFLRFQL-DHKFPDQRVVDAYNR 2391
            ++ ++ + E+   L  E  K E +   +S+ + +EA+ LL + GIPYI +P EAEAQCA L KK       +ED D   +    + +H+ FS       + +  + + + L L+ +  + + ++ G DY   + G+GPV A+++         + EF +  E + + +K+ E+   W  K +++L    E   GN        P+ K  + +   D KF ++RV    +R
Sbjct:  106 VETEKKLAEATTEL--EKMKQERRLVKVSKEHNEEAQKLLGLMGIPYIIAPTEAEAQCAELAKKGKVYAAASEDMDTLCYRTPFLLRHLTFSEAKKEPIHEIDTELVLRGLDLTIEQFVDLCIMLGCDYCESIRGVGPVTALKLIKTHGSIEKIVEFIESGESNNTKWKIPED---WPYKQARMLFLDPEVIDGNEINLKWSPPKEKELIEYLCDDKKFSEERVKSGISR 330          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Yeast
Match: DIN7 (Mitochondrial nuclease functioning in DNA repair and replication; modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination; DIN7 has a paralog, EXO1, that arose from the whole genome duplication [Source:SGD;Acc:S000002671])

HSP 1 Score: 69.3218 bits (168), Expect = 9.627e-13
Identity = 43/119 (36.13%), Postives = 64/119 (53.78%), Query Frame = 1
Query: 1891 DLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGG-CMVYK--------HVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSD 2220
            D  K+  IPYI +P EA+ Q  +LEK  L  G I+EDSD+ +FG   ++ K         +   DFSA    L   F +  LS+     +  L+G DYT G++ +G V AM+I+  +S+
Sbjct:  135 DYCKLHSIPYIVAPFEADPQMVYLEKMGLIQGIISEDSDLLVFGCKTLITKLNDQGKALEISKDDFSA----LPENFPLGELSEQQFRNLVCLAGCDYTSGIWKVGVVTAMKIVKRYSE 249          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Yeast
Match: EXO1 (5'-3' exonuclease and flap-endonuclease; involved in recombination, double-strand break repair, MMS2 error-free branch of the post replication (PRR) pathway and DNA mismatch repair; role in telomere maintenance; member of the Rad2p nuclease family, with conserved N and I nuclease domains; relative distribution to the nucleus increases upon DNA replication stress; EXO1 has a paralog, DIN7, that arose from the whole genome duplication [Source:SGD;Acc:S000005559])

HSP 1 Score: 67.3958 bits (163), Expect = 6.385e-12
Identity = 49/176 (27.84%), Postives = 84/176 (47.73%), Query Frame = 1
Query: 1771 NDPIQWQENIEESIANLYKEDHKIESQAASMSER-----YYQEAKDL-----------LKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHV--------FSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE 2226
             D I  +++ E    +  KE+  I  +  +  E+     Y+Q+  D+            K+ GI YI +P EA++Q  +LE+KN+  G I+EDSD+ +FG   +   +          RD       L   F +  L+ + +I +  LSG DYT G+  +G + AM+++  F+  E
Sbjct:   79 GDAIPVKKSTESKRRDKRKENKAIAERLWACGEKKNAMDYFQKCVDITPEMAKCIICYCKLNGIRYIVAPFEADSQMVYLEQKNIVQGIISEDSDLLVFGCRRLITKLNDYGECLEICRD---NFIKLPKKFPLGSLTNEEIITMVCLSGCDYTNGIPKVGLITAMKLVRRFNTIE 251          

HSP 2 Score: 57.7658 bits (138), Expect = 6.449e-9
Identity = 39/121 (32.23%), Postives = 60/121 (49.59%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRS-----GIDSP-NVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKI-----KSNIIDLLMK 432
            MG+QGL   L      + L   EG+VLAID   WL++A  S      +  P + +L+   +R   L  +K++P  VFDG +  +KK T   RR  R+  +  +E++     K N +D   K
Sbjct:    1 MGIQGLLPQLKPIQNPVSLRRYEGEVLAIDGYAWLHRAACSCAYELAMGKPTDKYLQFFIKRFSLLKTFKVEPYLVFDGDAIPVKKSTESKRRDKRKENKAIAERLWACGEKKNAMDYFQK 121          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Yeast
Match: YEN1 (Holliday junction resolvase; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; homolog of human GEN1; similar to S. cerevisiae endonuclease Rth1p [Source:SGD;Acc:S000000843])

HSP 1 Score: 53.5286 bits (127), Expect = 1.270e-7
Identity = 47/179 (26.26%), Postives = 81/179 (45.25%), Query Frame = 1
Query: 1885 AKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHV--FSRDFSARAYS-------------------LKHIFKVLG--LSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDH 2352
             + LL +  I Y+ + GE EAQC +L+     +  ++ DSD  +FGG  + K+   F  DF   + +                   L  I KV G    +  ++  ++L G+DY  GV G+G   +++ LA+  DP      + + ++F +  D  S+ L K +    +KR   +  DH
Sbjct:  176 VRKLLDLMNISYVIACGEGEAQCVWLQVSGAVDFILSNDSDTLVFGGEKILKNYSKFYDDFGPSSITSHSPSRHHDSKESFVTVIDLPKINKVAGKKFDRLSLLFFSVLLGADYNRGVKGLGKNKSLQ-LAQCEDPNFSMEFYDIFKDFNL-EDLTSESLRKSRYRLFQKRLYLYCKDH 352          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Nematostella
Match: EDO45269 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTI4])

HSP 1 Score: 133.265 bits (334), Expect = 6.572e-35
Identity = 70/163 (42.94%), Postives = 106/163 (65.03%), Query Frame = 1
Query: 1798 IEESIANLYKEDHKIESQ-------AASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFK 2265
            +EE   NL +E   ++S+       +A +S     E+++LL++FG+P++ SP EAEAQCAFL+    T+GTIT+DSD++LFGG  VYK++F+++  A  Y+ + I K L LS+  MI +A ++GSDYT G+ G+G V AME+L EFS     Q  F  L+  +
Sbjct:   93 LEEMQTNLNREQRTLQSERARQARASAEVSTEMLNESQELLRLFGVPFLVSPMEAEAQCAFLDMTGQTDGTITDDSDVFLFGGRRVYKNIFNQNKHAECYTCEDIDKGLALSRSKMIKLAFVTGSDYTEGIQGLGAVSAMEVLHEFS-----QDGFAALKELR 250          

HSP 2 Score: 114.005 bits (284), Expect = 2.471e-28
Identity = 54/118 (45.76%), Postives = 78/118 (66.10%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALR-----SGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINR----------RKLRQLKQEKSEKIKSN 411
            MGV+GLW +L   G+ + L SL+GKVLA+D SI +NQA++     SG   PN HL +LF R+CKLLFY++KPVFVFDG  P LKK+T++            R+ R L+ E++ + +++
Sbjct:    1 MGVKGLWQLLEPVGKPVTLESLQGKVLAVDASILMNQAIKGMRDGSGNPVPNAHLFVLFHRLCKLLFYRVKPVFVFDGGVPVLKKKTLVRAYLEEMQTNLNREQRTLQSERARQARAS 118          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Nematostella
Match: FEN1 (Flap endonuclease 1 [Source:UniProtKB/Swiss-Prot;Acc:A7RRJ0])

HSP 1 Score: 88.9669 bits (219), Expect = 7.526e-19
Identity = 50/145 (34.48%), Postives = 80/145 (55.17%), Query Frame = 1
Query: 1837 KIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENF 2262
            K   +   +++ + +E K LLK+ GIPY+E+P EAEAQCA L K      T TED D   FG  ++ +H+    ++    + + L+++    GLSQD  I + +L G DY   + GIGP  +++++ +     ID    K+LEN 
Sbjct:  125 KFSRRLVRVTKEHNEECKQLLKLMGIPYVEAPCEAEAQCAALVKSGKVYATGTEDMDALTFGTTVMLRHLTFSEAKKMPIKEFHLQNVLSEAGLSQDEFIDLCILLGCDYCDSIKGIGPKRSVDLIRQHRS--ID----KILENI 263          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Nematostella
Match: EDO29141 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4H2])

HSP 1 Score: 68.1662 bits (165), Expect = 2.012e-14
Identity = 32/60 (53.33%), Postives = 42/60 (70.00%), Query Frame = 1
Query:  190 DMSIWLNQALRSGIDS-----PNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETII 354
            D SI +NQA++   D      PN  L +LF R+CKLLFY++KPVFVFDG  P LKK+T++
Sbjct:    1 DASILMNQAVKGMRDGFGNPVPNAPLFVLFHRLCKLLFYRVKPVFVFDGGVPVLKKKTLV 60          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Nematostella
Match: EDO44985 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUB0])

HSP 1 Score: 68.9366 bits (167), Expect = 2.702e-13
Identity = 41/95 (43.16%), Postives = 53/95 (55.79%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQA-----LRSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR 372
            MGV  LWNIL    ++  L SL GK L +D+S W+ +A     L++ +  P  HL  LF RI +L    +K VFV DG  P LK E II R + R
Sbjct:    1 MGVTQLWNILEPVKKEGSLCSLRGKRLCVDLSCWICEANGAKGLKTNVLKP--HLRNLFFRIWQLTRCGVKLVFVVDGEPPELKWEAIIKRTQAR 93          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Nematostella
Match: EDO31577 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXI5])

HSP 1 Score: 59.3066 bits (142), Expect = 2.247e-9
Identity = 51/177 (28.81%), Postives = 84/177 (47.46%), Query Frame = 1
Query: 1909 GIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARA--YSLKHIFKVLGLSQDLMIC-----IALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQP 2418
            G+  I +P EA+AQ A+L KKN+    I+EDSD+ ++G     K +F  D S      SL H+ ++  L            + +LSG DY P + GIG + A ++L   S+      +  ++ N +M         ++Y+   + ++  + Q D  F  QRV D  +  LV  +  P
Sbjct:  141 GVDCIVAPYEADAQLAYLMKKNIIQAVISEDSDLLVYG---CKKVMFKMDASGYGTLVSLDHLSELTNLKMHEFTLEKFRHMCILSGCDYLPSIKGIGLIKANKLLRNSSNINKACINLTLVRNLRMD--------DQYRVPVDYEKSFK-QADETFLYQRVFDPVSCELVPLNPIP 305          

HSP 2 Score: 57.3806 bits (137), Expect = 9.000e-9
Identity = 31/96 (32.29%), Postives = 50/96 (52.08%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQ-ALRSGID-----SPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR 372
            MG+QGL  +L    R +++S  +G+ + +D   WL++ A    +D        V++  + +RI  +LF+ +KPV VFDG     K      RRK R
Sbjct:    1 MGIQGLLPLLKPIHRSVNISEFKGQTVGVDAYCWLHKGAYGCAMDLVEGKKTTVYINYVLKRINMMLFHDVKPVLVFDGAYLPSKANKEAERRKSR 96          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Medaka
Match: ercc5 (ERCC excision repair 5, endonuclease [Source:NCBI gene;Acc:101173290])

HSP 1 Score: 176.792 bits (447), Expect = 5.141e-45
Identity = 95/249 (38.15%), Postives = 142/249 (57.03%), Query Frame = 1
Query: 1813 ANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLE--KYKGNPE----RKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIEMLNVVSKNYGSKK 2541
            +NL  +  + E  A +++ + Y E+++LL++FG+P++ +P EAEAQCA L++ + T+GTIT+DSD+WLFGG  VYK+ FS++     Y    +   LGL +  MI +A L GSDY  GV G+G V  MEIL EF  P ++      L+ F  W   WS+  E  +   +P+    +K+    +L   FP+  V  AY  P VD S   F W RP +D + +F  S+ GW   K  E+L  V K   S++
Sbjct:  669 SNLKDQKQQQERMANTVTGQMYLESQELLRLFGVPFLVAPMEAEAQCAALDRADQTHGTITDDSDVWLFGGRHVYKNFFSQNKYVEHYQYSDLQNQLGLDRAKMINLAYLLGSDYAEGVPGVGYVTGMEILNEFPGPGLE-----PLKQFSQW---WSQAQENKRLTADPQDTKVKKKLRALKLQSGFPNPAVAQAYLEPAVDPSCSSFSWGRPQLDVIKEFCLSRFGWSSRKTEEILQPVVKQLNSQQ 909          

HSP 2 Score: 150.214 bits (378), Expect = 1.384e-36
Identity = 101/306 (33.01%), Postives = 165/306 (53.92%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQAL-----RSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNK-----------SEADDLFQLPENEYYDTISMNQ--FETEFGISDTALDYLSNFSS--MNEVNLESGSFKSMPLEVQHEII---RYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRK--QQLNDLPA-TINTRKILSRNDGYLMMI 942
            MGV GLW +L STG+ I+  +LEGK+LA+D+SIWLNQA+     R G    N HL  LF RICKLLF++I+PVFVFDG +P LKK+T+  RR+ ++    +S++    ++   +K++ + K     H+K            E DDL+ LP     + +  N+    +    S    D    +     N V++ S  F S+P E++HE++   R  +K +R  ++         SGD FS  Q+  LL RN L  ++E +   M    +Q+  GS ++  Q+  DL + ++   +++S ++ + ++I
Sbjct:    1 MGVHGLWRLLESTGKPINPETLEGKILAVDISIWLNQAVKGVRDREGNSVQNAHLLTLFHRICKLLFFRIRPVFVFDGDAPLLKKQTLAQRRQRKEELTRESKQTNEKLLKTFLKRQAI-KAALGDHSKDPLPSLSSVRRDEVDDLYVLPAVPPAEDVEKNRSPSPSSEEESQEEADSFHAYQEEDPNSVDINSEEFASLPAEMRHEMLKEMREFSKRRRTMFHKPPEC----SGD-FSQYQLAGLLQRNRLNLRLEGVEKEM----SQHSAGSAQQLCQREGDLVSHSVEANRLVSEDNSHYILI 296          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Medaka
Match: ENSORLT00000039492.1 (GEN1 Holliday junction 5' flap endonuclease [Source:NCBI gene;Acc:101167838])

HSP 1 Score: 80.8777 bits (198), Expect = 3.860e-15
Identity = 41/137 (29.93%), Postives = 74/137 (54.01%), Query Frame = 1
Query: 1879 QEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYK--HVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTP-GVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDK 2280
            +E  ++L   G+P++ + GEAEA CA+L+ + L +G IT D D +L+G   VY+  ++ S+D     Y    +   L LS++ ++ +A+L G DY P G+ G+G   A+ ++       +       L+ F  W ++
Sbjct:  117 KECAEMLDYLGVPWVMAAGEAEAMCAYLDSQGLVDGCITNDGDAFLYGARTVYRNFNMSSKDPQIDCYQTSRVQTELNLSRENLVGLAILLGCDYIPKGIPGVGKEQALRLIQALKGDSL-------LQRFIQWREE 246          

HSP 2 Score: 71.2478 bits (173), Expect = 3.506e-12
Identity = 39/95 (41.05%), Postives = 52/95 (54.74%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLN-----QALRSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLR 372
            MGV  LW+I+      + L SL GK LA+D+S+W+      QA+   +  P  HL  LF R+  L    IK VFV +G +P LK ET+  R K R
Sbjct:    1 MGVHDLWSIVEPVRESVSLYSLSGKTLAVDLSLWVCEAQHVQAMMGRVTKP--HLRNLFFRVSSLSLMGIKLVFVMEGTAPKLKAETMSKRTKAR 93          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Medaka
Match: fen1 (flap structure-specific endonuclease 1 [Source:NCBI gene;Acc:101158562])

HSP 1 Score: 76.2554 bits (186), Expect = 3.096e-14
Identity = 44/144 (30.56%), Postives = 76/144 (52.78%), Query Frame = 1
Query: 1789 QENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAE 2211
            QEN+E+    L K           +++++  E K LL + G+PYIE+P EAEA CA L K+     T TED D   FG  ++ +H+    ++    + +    I + + L+++  I + +L G DY   + GIGP  A++++ +
Sbjct:  120 QENVEKFTKRLVK-----------VTKQHNDECKKLLSLMGVPYIEAPCEAEASCAALVKEGKVFATATEDMDGLTFGTNVLLRHLTASEAKKLPIQEFHFNRILQDMDLTKEQFIDLCILLGCDYCGTIKGIGPKRAVDLIRQ 252          

HSP 2 Score: 50.447 bits (119), Expect = 5.074e-6
Identity = 36/110 (32.73%), Postives = 56/110 (50.91%), Query Frame = 1
Query:  103 MGVQGLWNILH----STGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNV----------HLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEK 390
            MG+ GL  ++     S  ++ D+ S  G+ +AID S+ + Q L +     NV          HL  +F R  ++L + IKPV+VFDG  P LK    + +R  R+ + EK
Sbjct:    1 MGIHGLAKLIADHAPSAIKEQDIKSYFGRKIAIDASMCMYQFLIAVRQDGNVLQNEDGETTSHLMGMFYRTIRMLEHGIKPVYVFDGKPPQLKSSE-LEKRGERRAEAEK 109          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Medaka
Match: fen1 (flap structure-specific endonuclease 1 [Source:NCBI gene;Acc:101158562])

HSP 1 Score: 76.6406 bits (187), Expect = 3.299e-14
Identity = 44/144 (30.56%), Postives = 76/144 (52.78%), Query Frame = 1
Query: 1789 QENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAE 2211
            QEN+E+    L K           +++++  E K LL + G+PYIE+P EAEA CA L K+     T TED D   FG  ++ +H+    ++    + +    I + + L+++  I + +L G DY   + GIGP  A++++ +
Sbjct:  172 QENVEKFTKRLVK-----------VTKQHNDECKKLLSLMGVPYIEAPCEAEASCAALVKEGKVFATATEDMDGLTFGTNVLLRHLTASEAKKLPIQEFHFNRILQDMDLTKEQFIDLCILLGCDYCGTIKGIGPKRAVDLIRQ 304          

HSP 2 Score: 50.447 bits (119), Expect = 6.873e-6
Identity = 36/110 (32.73%), Postives = 56/110 (50.91%), Query Frame = 1
Query:  103 MGVQGLWNILH----STGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNV----------HLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEK 390
            MG+ GL  ++     S  ++ D+ S  G+ +AID S+ + Q L +     NV          HL  +F R  ++L + IKPV+VFDG  P LK    + +R  R+ + EK
Sbjct:   53 MGIHGLAKLIADHAPSAIKEQDIKSYFGRKIAIDASMCMYQFLIAVRQDGNVLQNEDGETTSHLMGMFYRTIRMLEHGIKPVYVFDGKPPQLKSSE-LEKRGERRAEAEK 161          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Medaka
Match: fen1 (flap structure-specific endonuclease 1 [Source:NCBI gene;Acc:101158562])

HSP 1 Score: 76.6406 bits (187), Expect = 3.593e-14
Identity = 44/144 (30.56%), Postives = 76/144 (52.78%), Query Frame = 1
Query: 1789 QENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAE 2211
            QEN+E+    L K           +++++  E K LL + G+PYIE+P EAEA CA L K+     T TED D   FG  ++ +H+    ++    + +    I + + L+++  I + +L G DY   + GIGP  A++++ +
Sbjct:  172 QENVEKFTKRLVK-----------VTKQHNDECKKLLSLMGVPYIEAPCEAEASCAALVKEGKVFATATEDMDGLTFGTNVLLRHLTASEAKKLPIQEFHFNRILQDMDLTKEQFIDLCILLGCDYCGTIKGIGPKRAVDLIRQ 304          

HSP 2 Score: 50.0618 bits (118), Expect = 7.444e-6
Identity = 36/110 (32.73%), Postives = 56/110 (50.91%), Query Frame = 1
Query:  103 MGVQGLWNILH----STGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNV----------HLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEK 390
            MG+ GL  ++     S  ++ D+ S  G+ +AID S+ + Q L +     NV          HL  +F R  ++L + IKPV+VFDG  P LK    + +R  R+ + EK
Sbjct:   53 MGIHGLAKLIADHAPSAIKEQDIKSYFGRKIAIDASMCMYQFLIAVRQDGNVLQNEDGETTSHLMGMFYRTIRMLEHGIKPVYVFDGKPPQLKSSE-LEKRGERRAEAEK 161          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Planmine SMEST
Match: SMESG000019370.1 (SMESG000019370.1)

HSP 1 Score: 1523.84 bits (3944), Expect = 0.000e+0
Identity = 771/786 (98.09%), Postives = 779/786 (99.11%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDIVDNLTKLKSEYLFKKHDQNIEQNYHKIPGNVDNSVKSIDSPIVSYVNSEYVHKEKTDSLCPQDLEKIRDNSISSVTSQSGLNVDNPASEIDDINEFYIEKPSTSVSDSVQNKFDIKKTLELRSSSDTDNNENAVDSSDSMKHNANMMCNNKLDELASINNVSVSEYKNDIANYINNDIPSLSNYCYEDTKKSTENKSIVNNTINNSIYSAEFEEKKKRSMKTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXIESEEINKFSDADIAMILNDPIQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDF 2460
            MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNVHLE+LFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRK+VSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLES SFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDIVDNLTKLKSEYLFKKHDQNIEQNYHKIPGNVDNSVKSIDSPIVSYVNSEYVHKEKTDSLCPQDLEKIRDNSISSVTSQ GLNVDN ASEIDDINEFYIEKPSTSVSDSVQNKFDIKKTLELRSSSDTDNNENAVDSSDSMKHNANMMCNNKLDELASINNVSVSEYKNDIANYINNDIPSLSNYCYEDTKKSTENKSIVNNTINNSIYSAEFEEKKKRSMKTN    +EEE++EEEE+DDFVDVPEVNVDEIESEEINKFSDADIAMILNDPIQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLL++
Sbjct:    1 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNVHLEVLFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKTVSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESESFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDIVDNLTKLKSEYLFKKHDQNIEQNYHKIPGNVDNSVKSIDSPIVSYVNSEYVHKEKTDSLCPQDLEKIRDNSISSVTSQYGLNVDNTASEIDDINEFYIEKPSTSVSDSVQNKFDIKKTLELRSSSDTDNNENAVDSSDSMKHNANMMCNNKLDELASINNVSVSEYKNDIANYINNDIPSLSNYCYEDTKKSTENKSIVNNTINNSIYSAEFEEKKKRSMKTN--EVDEEEEKEEEEDDDFVDVPEVNVDEIESEEINKFSDADIAMILNDPIQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLEY 784          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Planmine SMEST
Match: SMESG000019370.1 (SMESG000019370.1)

HSP 1 Score: 1523.84 bits (3944), Expect = 0.000e+0
Identity = 772/786 (98.22%), Postives = 780/786 (99.24%), Query Frame = 1
Query:  103 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNVHLEILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDIVDNLTKLKSEYLFKKHDQNIEQNYHKIPGNVDNSVKSIDSPIVSYVNSEYVHKEKTDSLCPQDLEKIRDNSISSVTSQSGLNVDNPASEIDDINEFYIEKPSTSVSDSVQNKFDIKKTLELRSSSDTDNNENAVDSSDSMKHNANMMCNNKLDELASINNVSVSEYKNDIANYINNDIPSLSNYCYEDTKKSTENKSIVNNTINNSIYSAEFEEKKKRSMKTNXXXXXXXXXXXXXXXXXXXXXXXXXXXXIESEEINKFSDADIAMILNDPIQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDF 2460
            MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNVHLE+LFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRK+VSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLES SFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDIVDNLTKLKSEYLFKKHDQNIEQNYHKIPGNVDNSVKSIDSPIVSYVNSEYVHKEKTDSLCPQDLEKIRDNSISSVTSQ GLNVDN ASEIDDINEFYIEKPSTSVSDSVQNKFDIKKTLELRSSSDTDNNENAVDSSDSMKHNANMMCNNKLDELASINNVSVSEYKNDIANYINNDIPSLSNYCYEDTKKSTENKSIVNNTINNSIYSAEFEEKKKRSMKTN E  +EEE++EEEE+DDFVDVPEVNVDEIESEEINKFSDADIAMILNDPIQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLL++
Sbjct:    1 MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNVHLEVLFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKIKSNIIDLLMKKKLVEKRKTVSHNKSEADDLFQLPENEYYDTISMNQFETEFGISDTALDYLSNFSSMNEVNLESESFKSMPLEVQHEIIRYIAKEKRYGYNTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIGSLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDIVDNLTKLKSEYLFKKHDQNIEQNYHKIPGNVDNSVKSIDSPIVSYVNSEYVHKEKTDSLCPQDLEKIRDNSISSVTSQYGLNVDNTASEIDDINEFYIEKPSTSVSDSVQNKFDIKKTLELRSSSDTDNNENAVDSSDSMKHNANMMCNNKLDELASINNVSVSEYKNDIANYINNDIPSLSNYCYEDTKKSTENKSIVNNTINNSIYSAEFEEKKKRSMKTN-EEVDEEEEKEEEEDDDFVDVPEVNVDEIESEEINKFSDADIAMILNDPIQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDHKFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLEY 785          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Planmine SMEST
Match: SMESG000020104.1 (SMESG000020104.1)

HSP 1 Score: 85.1149 bits (209), Expect = 2.628e-17
Identity = 61/216 (28.24%), Postives = 101/216 (46.76%), Query Frame = 1
Query: 1783 QWQENIEESIANLYKEDH-----KIESQAASMSERYYQEAKDLLKIFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVF---SRDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEILAEFSDPE-----IDQSHFKVLENFKMWHDKWSK--LLEKYKGNPERKRFLRFQLDHKFPDQRVVDAY 2385
            + +E  E+ +    KED      K   +   +  ++ ++ K LL + GIPYI +P EAEAQCA + K        TED D   FGG ++ + +    ++    + Y+L  I   + L+ +  I + +L G DY P + GIGP  A+E++ +    E     ID   + + EN   W+ K ++   LE    +PE       +L    PD+  +  Y
Sbjct:  102 ERREEAEKQLEVAQKEDDAENIDKFSKRLVKVLPKHNEDCKKLLSLMGIPYITAPCEAEAQCAAMVKAKKVFAVGTEDMDALTFGGSILLRRLTFSEAKKLPIQEYNLDKILSKMELTMEQFIDLCILLGCDYCPSIRGIGPKKAVELIKKHKSLESVIENIDNKKYPLPEN---WNYKGARQLFLEPEVTDPE-----TIELKWALPDEEGIIQY 309          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Planmine SMEST
Match: SMESG000064333.1 (SMESG000064333.1)

HSP 1 Score: 62.003 bits (149), Expect = 1.344e-9
Identity = 44/117 (37.61%), Postives = 63/117 (53.85%), Query Frame = 1
Query: 1885 AKDLLKI---FGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARA--YSLKHIFKVLGL-----SQDLMICIALLSGSDYTPGVYGIGPVIAMEIL 2205
            A  L+KI    G+  I +P EA+AQ A+L K  + +  ITEDSD+ LFG     K +F  DF+  A    +  I KVL       S +    + ++SG DY PG+ GIG + A ++L
Sbjct:  130 AVKLIKIGHSLGVKCIVAPYEADAQLAYLGKNLIVDYVITEDSDLLLFG---TPKVLFKLDFNGLANLIEINDINKVLKFPLEKYSYNKFRYMCIISGCDYFPGLAGIGLITAAKLL 243          
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Planmine SMEST
Match: SMESG000064333.1 (SMESG000064333.1)

HSP 1 Score: 61.6178 bits (148), Expect = 1.580e-9
Identity = 44/117 (37.61%), Postives = 63/117 (53.85%), Query Frame = 1
Query: 1885 AKDLLKI---FGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFSRDFSARA--YSLKHIFKVLGL-----SQDLMICIALLSGSDYTPGVYGIGPVIAMEIL 2205
            A  L+KI    G+  I +P EA+AQ A+L K  + +  ITEDSD+ LFG     K +F  DF+  A    +  I KVL       S +    + ++SG DY PG+ GIG + A ++L
Sbjct:  130 AVKLIKIGHSLGVKCIVAPYEADAQLAYLGKNLIVDYVITEDSDLLLFG---TPKVLFKLDFNGLANLIEINDINKVLKFPLEKYSYNKFRYMCIISGCDYFPGLAGIGLITAAKLL 243          
The following BLAST results are available for this feature:
BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ERCC55.223e-4535.22ERCC excision repair 5, endonuclease [Source:HGNC ... [more]
ERCC57.413e-4535.22ERCC excision repair 5, endonuclease [Source:HGNC ... [more]
BIVM-ERCC51.213e-4435.22BIVM-ERCC5 readthrough [Source:HGNC Symbol;Acc:HGN... [more]
ERCC51.271e-4435.22ERCC excision repair 5, endonuclease [Source:HGNC ... [more]
BIVM-ERCC51.271e-4435.22BIVM-ERCC5 readthrough [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
xpg-14.838e-2732.02XPG (Xeroderma Pigmentosum group G) DNA repair gen... [more]
crn-17.852e-1833.11Flap endonuclease 1 [Source:UniProtKB/Swiss-Prot;... [more]
crn-17.852e-1833.11Flap endonuclease 1 [Source:UniProtKB/Swiss-Prot;... [more]
gen-16.693e-1630.24GEN1 Holliday junction resolvase homolog [Source:... [more]
gen-16.693e-1630.24GEN1 Holliday junction resolvase homolog [Source:... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mus2015.507e-4737.46gene:FBgn0002887 transcript:FBtr0100473[more]
mus2015.507e-4737.46gene:FBgn0002887 transcript:FBtr0346117[more]
Fen14.235e-1730.86gene:FBgn0025832 transcript:FBtr0087075[more]
Gen8.497e-1235.19gene:FBgn0263831 transcript:FBtr0077176[more]
tos6.906e-628.04gene:FBgn0015553 transcript:FBtr0081131[more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ercc52.648e-4238.46excision repair cross-complementation group 5 [Sou... [more]
ercc56.565e-4036.60excision repair cross-complementation group 5 [Sou... [more]
ercc52.969e-3734.24excision repair cross-complementation group 5 [Sou... [more]
zgc:1102699.832e-1634.15zgc:110269 [Source:NCBI gene;Acc:550274][more]
FO834823.16.472e-1533.64pep chromosome:GRCz11:4:288633:292031:1 gene:ENSDA... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
amigo12.486e-4335.69adhesion molecule with Ig-like domain 1 [Source:Xe... [more]
amigo12.337e-4235.69adhesion molecule with Ig-like domain 1 [Source:Xe... [more]
amigo12.473e-4235.69adhesion molecule with Ig-like domain 1 [Source:Xe... [more]
amigo11.409e-4138.27adhesion molecule with Ig-like domain 1 [Source:Xe... [more]
GEN12.584e-1627.31GEN1 Holliday junction 5' flap endonuclease [Sourc... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ercc51.835e-4838.52excision repair cross-complementing rodent repair ... [more]
Fen11.872e-1730.18flap structure specific endonuclease 1 [Source:MGI... [more]
Fen11.872e-1730.18flap structure specific endonuclease 1 [Source:MGI... [more]
Fen11.872e-1730.18flap structure specific endonuclease 1 [Source:MGI... [more]
Fen11.872e-1730.18flap structure specific endonuclease 1 [Source:MGI... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P35689|ERCC5_MOUSE3.086e-4738.52DNA repair protein complementing XP-G cells homolo... [more]
sp|P14629|ERCC5_XENLA9.781e-4541.53DNA repair protein complementing XP-G cells homolo... [more]
sp|P28715|ERCC5_HUMAN3.560e-4435.22DNA repair protein complementing XP-G cells OS=Hom... [more]
sp|P07276|RAD2_YEAST5.929e-4139.24DNA repair protein RAD2 OS=Saccharomyces cerevisia... [more]
sp|Q9ATY5|UVH3_ARATH8.474e-3935.47DNA repair protein UVH3 OS=Arabidopsis thaliana OX... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1R3C02.399e-5841.27DNA repair protein complementing XP-G cells-like p... [more]
A0A443SNK81.545e-5742.63Uncharacterized protein OS=Leptotrombidium deliens... [more]
A0A1Z5KVX86.288e-5741.94DNA-repair protein xp-G (Fragment) OS=Ornithodoros... [more]
A0A2P6KGL47.449e-5741.06Ercc5 OS=Nephila clavipes OX=2585209 GN=NCL1_40921... [more]
A0A3S3PD511.211e-5643.31DNA repair protein complementing XP-G cells-like p... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ercc52.261e-4436.54ERCC excision repair 5, endonuclease [Source:NCBI ... [more]
ercc52.261e-4436.54ERCC excision repair 5, endonuclease [Source:NCBI ... [more]
ercc52.261e-4436.54ERCC excision repair 5, endonuclease [Source:NCBI ... [more]
ENSAMXT00000001764.22.977e-1535.58GEN1 Holliday junction 5' flap endonuclease [Sourc... [more]
fen12.112e-1426.02flap structure-specific endonuclease 1 [Source:NCB... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009203.14.117e-4537.50pep scaffold:Pmarinus_7.0:GL485931:6413:9971:-1 ge... [more]
ENSPMAT00000003090.11.233e-3250.42pep scaffold:Pmarinus_7.0:GL486553:1283:3042:-1 ge... [more]
ENSPMAT00000009133.19.971e-1636.04pep scaffold:Pmarinus_7.0:GL481492:6824:20158:-1 g... [more]
ENSPMAT00000009129.11.779e-1536.04pep scaffold:Pmarinus_7.0:GL481492:6818:20158:-1 g... [more]
ENSPMAT00000009136.12.636e-1533.90pep scaffold:Pmarinus_7.0:GL481492:10436:20158:-1 ... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
RAD28.539e-4339.24Single-stranded DNA endonuclease; cleaves single-s... [more]
RAD273.193e-1426.525' to 3' exonuclease, 5' flap endonuclease; requir... [more]
DIN79.627e-1336.13Mitochondrial nuclease functioning in DNA repair a... [more]
EXO16.385e-1227.845'-3' exonuclease and flap-endonuclease; involved ... [more]
YEN11.270e-726.26Holliday junction resolvase; promotes template swi... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO452696.572e-3542.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
FEN17.526e-1934.48Flap endonuclease 1 [Source:UniProtKB/Swiss-Prot;... [more]
EDO291412.012e-1453.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449852.702e-1343.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO315772.247e-928.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ercc55.141e-4538.15ERCC excision repair 5, endonuclease [Source:NCBI ... [more]
ENSORLT00000039492.13.860e-1529.93GEN1 Holliday junction 5' flap endonuclease [Sourc... [more]
fen13.096e-1430.56flap structure-specific endonuclease 1 [Source:NCB... [more]
fen13.299e-1430.56flap structure-specific endonuclease 1 [Source:NCB... [more]
fen13.593e-1430.56flap structure-specific endonuclease 1 [Source:NCB... [more]
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BLAST of DNA repair protein complementing XP-G cells-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000019370.10.000e+098.09SMESG000019370.1[more]
SMESG000019370.10.000e+098.22SMESG000019370.1[more]
SMESG000020104.12.628e-1728.24SMESG000020104.1[more]
SMESG000064333.11.344e-937.61SMESG000064333.1[more]
SMESG000064333.11.580e-937.61SMESG000064333.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006259 ID=SMED30006259|Name=DNA repair protein complementing XP-G cells-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2698bp
GTACTATATTTGTATAAATAAAATCTTTTAAAAAGTTTTCTAAGTAAAAT
ACTTTTAAATAACTAAAACAATAAATTCGGTTAAAAATTAGTTTTAAATC
AAATGGGAGTTCAAGGGCTGTGGAATATTTTACACAGTACTGGCAGAGAT
ATTGATTTATCCAGCCTTGAAGGGAAAGTTCTTGCAATTGATATGAGTAT
TTGGTTAAATCAAGCTCTGAGATCTGGAATAGATTCACCAAATGTCCACT
TGGAAATTTTATTTCGTAGAATTTGTAAACTTCTTTTTTATAAAATAAAA
CCAGTGTTCGTTTTTGATGGTCCTTCTCCATCCCTGAAAAAGGAAACAAT
TATAAACCGACGCAAATTACGTCAGCTGAAACAAGAGAAATCCGAAAAAA
TCAAATCAAACATCATTGATCTATTGATGAAAAAGAAACTCGTTGAAAAA
CGAAAATCCGTTAGTCACAATAAATCGGAAGCAGATGACTTGTTTCAATT
ACCCGAGAATGAATACTACGATACAATATCAATGAATCAATTCGAGACTG
AGTTCGGAATCTCCGACACCGCGCTTGATTACTTGAGTAATTTTTCTTCA
ATGAATGAAGTGAATTTAGAGTCAGGATCATTTAAATCTATGCCACTCGA
AGTTCAGCATGAAATTATTAGGTATATAGCTAAAGAAAAACGCTACGGAT
ATAATACAACTCAAAGTAGTTTTTTAAATAAGAGCGGAGATGAATTTTCC
TCGCTTCAAATCCAACGGCTATTAAGTCGCAATACACTGCAACAAAAAGT
AGAAGACTTAAGAACGTCTATGAATTACAGGAACAATCAAAATGTTATTG
GATCGTTAAGGAAACAACAGCTAAATGATTTACCAGCAACTATTAATACG
AGAAAAATTCTCTCTCGAAATGACGGTTACCTAATGATGATTGATCCTTC
AGAAACAGATATTGTTGACAACCTTACTAAATTGAAGTCTGAATATTTAT
TCAAAAAGCATGATCAAAATATTGAACAGAATTACCATAAAATTCCAGGC
AATGTTGATAATAGTGTGAAAAGTATTGATTCTCCAATTGTTTCTTACGT
AAACTCCGAATATGTTCATAAAGAAAAAACTGATTCACTTTGTCCTCAAG
ATTTAGAAAAAATTCGCGATAATTCCATTTCTTCTGTAACTAGCCAATCT
GGTTTGAATGTGGATAATCCAGCAAGTGAAATCGACGATATTAATGAATT
CTATATAGAAAAGCCATCCACTTCAGTTAGTGATTCCGTGCAAAACAAGT
TCGATATAAAAAAAACATTGGAATTAAGATCGAGTAGTGATACTGATAAT
AATGAAAATGCTGTAGATTCCAGTGATTCGATGAAGCATAATGCAAATAT
GATGTGTAATAATAAATTGGATGAATTGGCTTCGATAAATAATGTTTCCG
TATCAGAATATAAAAATGATATAGCTAATTATATCAATAATGACATTCCG
TCGCTCTCAAATTATTGTTATGAAGATACCAAAAAGAGTACTGAGAACAA
ATCCATTGTAAACAATACGATAAATAATTCTATATATTCTGCAGAATTTG
AAGAAAAAAAGAAAAGATCTATGAAGACTAATGAAGAAGTCGATGAAGAA
GAAGAAAAAGAAGAAGAAGAAGAAGAAGATGACTTTGTCGATGTACCAGA
AGTGAATGTTGATGAAATCGAATCTGAAGAAATAAATAAATTTTCTGATG
CAGATATTGCAATGATTCTCAATGATCCGATACAGTGGCAAGAAAATATT
GAAGAAAGTATTGCCAATCTTTACAAAGAAGATCATAAAATAGAGAGTCA
GGCTGCAAGTATGAGCGAAAGATATTATCAGGAAGCAAAAGATTTACTGA
AAATATTTGGTATTCCTTATATTGAAAGTCCTGGAGAGGCGGAAGCTCAA
TGTGCATTTCTTGAAAAGAAGAATTTGACCAATGGAACTATAACGGAAGA
TAGTGACATTTGGCTGTTTGGGGGTTGCATGGTTTATAAACATGTATTTT
CCCGAGATTTTTCTGCCAGAGCTTATTCATTAAAGCACATTTTCAAAGTT
CTCGGTCTGTCACAAGATCTCATGATTTGTATAGCTTTATTAAGTGGGAG
TGATTATACTCCTGGAGTTTACGGAATCGGTCCCGTGATAGCTATGGAAA
TACTAGCAGAATTTTCTGATCCTGAAATCGATCAGTCTCATTTTAAGGTT
TTGGAGAATTTCAAGATGTGGCACGATAAATGGTCAAAACTTCTTGAAAA
ATACAAAGGGAATCCAGAAAGGAAAAGATTTTTGAGATTCCAATTGGATC
ATAAATTTCCAGATCAAAGAGTTGTAGACGCCTACAACAGGCCTTTAGTT
GATGAGTCTGAGCAACCTTTTATTTGGTCAAGACCTTCCATAGATCAATT
ATTAGATTTTGCGCAGTCGAAAATAGGCTGGGAACGTTTGAAAGTTATTG
AAATGCTAAATGTAGTCAGTAAAAATTATGGATCGAAAAAATTATTTTGT
CAAAAGAGCATTCTTGATTATTTCACTGATTCTAAAGTCGATGAACTGAT
GAATAGTAAGCGGTCCCCCAGTAAGCGCTTGCGCTTGGCCACAAGGCAAG
CAAATCTCATTGCTGATAACATTAAAAAGATTAAAAAATAAATGTCTA
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protein sequence of SMED30006259-orf-1

>SMED30006259-orf-1 ID=SMED30006259-orf-1|Name=SMED30006259-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=110bp
MEKDHQKRTLVLFYKKEVYKFYEIKFPSGHLVNLFQISELDLTKYSYQLQ
ELSLQGWINQYLCQYCVKYSTALELPFDLKLIFNRIYCFSYLKVFYLENF
LKDFIYTNIV
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protein sequence of SMED30006259-orf-2

>SMED30006259-orf-2 ID=SMED30006259-orf-2|Name=SMED30006259-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=863bp
MGVQGLWNILHSTGRDIDLSSLEGKVLAIDMSIWLNQALRSGIDSPNVHL
EILFRRICKLLFYKIKPVFVFDGPSPSLKKETIINRRKLRQLKQEKSEKI
KSNIIDLLMKKKLVEKRKSVSHNKSEADDLFQLPENEYYDTISMNQFETE
FGISDTALDYLSNFSSMNEVNLESGSFKSMPLEVQHEIIRYIAKEKRYGY
NTTQSSFLNKSGDEFSSLQIQRLLSRNTLQQKVEDLRTSMNYRNNQNVIG
SLRKQQLNDLPATINTRKILSRNDGYLMMIDPSETDIVDNLTKLKSEYLF
KKHDQNIEQNYHKIPGNVDNSVKSIDSPIVSYVNSEYVHKEKTDSLCPQD
LEKIRDNSISSVTSQSGLNVDNPASEIDDINEFYIEKPSTSVSDSVQNKF
DIKKTLELRSSSDTDNNENAVDSSDSMKHNANMMCNNKLDELASINNVSV
SEYKNDIANYINNDIPSLSNYCYEDTKKSTENKSIVNNTINNSIYSAEFE
EKKKRSMKTNEEVDEEEEKEEEEEEDDFVDVPEVNVDEIESEEINKFSDA
DIAMILNDPIQWQENIEESIANLYKEDHKIESQAASMSERYYQEAKDLLK
IFGIPYIESPGEAEAQCAFLEKKNLTNGTITEDSDIWLFGGCMVYKHVFS
RDFSARAYSLKHIFKVLGLSQDLMICIALLSGSDYTPGVYGIGPVIAMEI
LAEFSDPEIDQSHFKVLENFKMWHDKWSKLLEKYKGNPERKRFLRFQLDH
KFPDQRVVDAYNRPLVDESEQPFIWSRPSIDQLLDFAQSKIGWERLKVIE
MLNVVSKNYGSKKLFCQKSILDYFTDSKVDELMNSKRSPSKRLRLATRQA
NLIADNIKKIKK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR0362795-3_exonuclease_C_sf
IPR006084XPG/Rad2
IPR008918HhH2
IPR006085XPG_DNA_repair_N
IPR006086XPG-I_dom
IPR029060PIN-like_dom_sf
IPR019974XPG_CS
IPR0200455-3_exonuclease_C
Vocabulary: biological process
TermDefinition
GO:0006281DNA repair
GO:0006289nucleotide-excision repair
GO:0090305nucleic acid phosphodiester bond hydrolysis
Vocabulary: molecular function
TermDefinition
GO:0004518nuclease activity
GO:0003677DNA binding
GO:0003824catalytic activity
GO:0016788hydrolase activity, acting on ester bonds
GO:0003697single-stranded DNA binding
GO:0004519endonuclease activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 496..526
NoneNo IPR availableGENE3DG3DSA:3.40.50.1010coord: 1..140
e-value: 4.4E-27
score: 96.7
NoneNo IPR availableGENE3DG3DSA:3.40.50.1010coord: 566..837
e-value: 4.1E-48
score: 166.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 501..526
NoneNo IPR availablePANTHERPTHR16171FAMILY NOT NAMEDcoord: 1..325
NoneNo IPR availablePANTHERPTHR16171:SF7DNA REPAIR PROTEIN RAD2coord: 388..836
NoneNo IPR availablePANTHERPTHR16171:SF7DNA REPAIR PROTEIN RAD2coord: 1..325
NoneNo IPR availablePANTHERPTHR16171FAMILY NOT NAMEDcoord: 388..836
NoneNo IPR availableCDDcd09868PIN_XPG_RAD2coord: 2..108
e-value: 1.46326E-46
score: 163.457
NoneNo IPR availableCDDcd09868PIN_XPG_RAD2coord: 585..669
e-value: 2.30461E-35
score: 131.486
IPR006084XPG/Rad2 endonucleasePRINTSPR00853XPGRADSUPERcoord: 598..615
score: 54.86
coord: 67..86
score: 49.22
coord: 619..639
score: 46.28
coord: 673..688
score: 42.19
coord: 24..38
score: 50.0
IPR008918Helix-hairpin-helix motif, class 2SMARTSM00279HhH_4coord: 670..703
e-value: 4.1E-7
score: 39.6
IPR006086XPG-I domainSMARTSM00484xpgineucoord: 599..668
e-value: 1.3E-24
score: 97.8
IPR006086XPG-I domainPFAMPF00867XPG_Icoord: 600..683
e-value: 1.9E-21
score: 76.2
IPR006085XPG N-terminalSMARTSM00485xpgn3coord: 1..93
e-value: 5.5E-33
score: 125.6
IPR006085XPG N-terminalPFAMPF00752XPG_Ncoord: 1..91
e-value: 4.5E-24
score: 84.9
IPR019974XPG conserved sitePROSITEPS00841XPG_1coord: 65..79
IPR029060PIN-like domain superfamilySUPERFAMILYSSF88723PIN domain-likecoord: 2..683
IPR0362795'-3' exonuclease, C-terminal domain superfamilySUPERFAMILYSSF478075' to 3' exonuclease, C-terminal subdomaincoord: 668..823