slc18a-5

Overview


Name	slc18a-5 (AKN21540.1)
Smed ID	SMED30006235
Length (bp)	1500

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of slc18a-5 (SMED30006235) t-SNE clustered cells

Violin plots show distribution of expression levels for slc18a-5 (SMED30006235) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc18a-5 (SMED30006235) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc18a-5 (SMED30006235) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30006235

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30006235	SMESG000024277.1	SmedASXL_000496	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30006235	SMESG000024277.1	dd_Smed_v4_13278_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30006235	SMESG000024277.1	dd_Smed_v6_13278_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30006235	SMESG000024277.1	dd_Smed_v4_13278_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of slc18a-5 vs. Ensembl Human
Match: SLC18A3 (solute carrier family 18 member A3 [Source:HGNC Symbol;Acc:HGNC:10936])

HSP 1 Score: 68.9366 bits (167), Expect = 8.256e-12
Identity = 75/334 (22.46%), Postives = 132/334 (39.52%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGS-VGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKER-KLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKM 1278
            ++ +L+ +K I Q++V+   G  +DR+     LLIG+ +   + VL+     Y  L   R  +G+ S     S  A IA K+  +  R +  G V+L     GS V P +GG +Y++  K + FL++     F    L++L V K      + R  L      H                                 R +LDPY  +   +     +    L  T+  ++K     +E++ G+ W    V ++LG  L   L  +  + +     + L V   +S IV A   +      +C +     + D    P L+ + + +H   YG +
Sbjct:  123 KIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALG-VALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDA--LLLLAVAKPFSAAARARANLPVGTPIH---------------------------------RLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV 420

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BLAST of slc18a-5 vs. Ensembl Human
Match: SLC18A1 (solute carrier family 18 member A1 [Source:HGNC Symbol;Acc:HGNC:10934])

HSP 1 Score: 58.9214 bits (141), Expect = 1.426e-8
Identity = 85/393 (21.63%), Postives = 169/393 (43.00%), Query Frame = 1

Query:  256 SGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLL-DPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            +GF + + +++ +L+ +K + Q++V+  +G + +RIG    +  G ++  ++ V++     Y +L + R  +GI S+    +    +A  +     RG+  G     + L   VG  +G  +Y++  K+  FL++            + L++  L + + +   V+  S                              KG+ +  LL DPY L+A  S     M   IL  TLP ++ +     ++Q GL +   +V YL+G  L  +L  K+  R    L+ +L V +    +  A   + +   P   +     + D    PI+  + + +H   YG +  +      +  +I  S G  ++K IG   L +I   +N++Y PL ++L+ 
Sbjct:  129 TGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLIL----------AFLALLDGALQLCILQPSKVSPES-----------------------------AKGTPLFMLLKDPYILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKM-GRWLCSLIGMLVVGTSLLCVPLAHNIFGLIG-PNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480

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Query:  256 SGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLL-DPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            +GF + + +++ +L+ +K + Q++V+  +G + +RIG    +  G ++  ++ V++     Y +L + R  +GI S+    +    +A  +     RG+  G     + L   VG  +G  +Y++  K+  FL++            + L++  L + + +   V+  S                              KG+ +  LL DPY L+A  S     M   IL  TLP ++ +     ++Q GL +   +V YL+G  L  +L  K+  R    L+ +L V +    +  A   + +   P   +     + D    PI+  + + +H   YG +  +      +  +I  S G  ++K IG   L +I   +N++Y PL ++L+ 
Sbjct:  129 TGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLIL----------AFLALLDGALQLCILQPSKVSPES-----------------------------AKGTPLFMLLKDPYILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKM-GRWLCSLIGMLVVGTSLLCVPLAHNIFGLIG-PNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480

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BLAST of slc18a-5 vs. Ensembl Human
Match: SLC18A2 (solute carrier family 18 member A2 [Source:HGNC Symbol;Acc:HGNC:10935])

HSP 1 Score: 56.9954 bits (136), Expect = 5.682e-8
Identity = 59/265 (22.26%), Postives = 111/265 (41.89%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLL-DPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
            Q+ +L+ +K   Q+I +  IG + +RIG    +  G  +  V+ +++   S Y  L++ R  +GI S+    +    +A  +   + RG   G     + +   VGP +G  +Y++  KT  FL++            ++L++  + + V +   V   S                              KG+ +  LL DPY LIA  S     M   +L   LP ++ +     ++Q G+ +   ++ YL+G  +  IL  K+
Sbjct:  130 QVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVL----------AALVLLDGAIQLFVLQPSRVQPES-----------------------------QKGTPLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKM 355

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BLAST of slc18a-5 vs. Ensembl Human
Match: SLC18A1 (solute carrier family 18 member A1 [Source:HGNC Symbol;Acc:HGNC:10934])

HSP 1 Score: 50.0618 bits (118), Expect = 5.620e-6
Identity = 60/274 (21.90%), Postives = 119/274 (43.43%), Query Frame = 1

Query:  256 SGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLL-DPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
            +GF + + +++ +L+ +K + Q++V+  +G + +RIG    +  G ++  ++ V++     Y +L + R  +GI S+    +    +A  +     RG+  G     + L   VG  +G  +Y++  K+  FL++            + L++  L + + +   V+  S                              KG+ +  LL DPY L+A  S     M   IL  TLP ++ +     ++Q GL +   +V YL+G  L  +L  K+
Sbjct:  129 TGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLIL----------AFLALLDGALQLCILQPSKVSPES-----------------------------AKGTPLFMLLKDPYILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKM 363

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BLAST of slc18a-5 vs. Ensembl Celegans
Match: cat-1 (pep chromosome:WBcel235:X:5705719:5710585:-1 gene:WBGene00000295.1 transcript:W01C8.6b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cat-1)

HSP 1 Score: 78.9518 bits (193), Expect = 1.882e-15
Identity = 89/393 (22.65%), Postives = 166/393 (42.24%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLL-DPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGF-ILGNILNTKLQNRRHYV-LVVILF----VNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 1440
             + +++G+K + Q++V+  IG + +RIG    +  G ++   + +L+  G  YF L L R  +G+ S     S    +A  +     RG   G     + L   VGP YGG +YQ+  K L F+L+ +   F          +  +   V + K+                                   +GS I+ L  DPY ++A  +  +  +   +L  +LP ++ + +G    ++G  +   ++ YL+G  I G + +   +    ++ LVVI F    + S TSV    +P+  +  F + +I        MF  P++  + + +H   YG +  +         ++       L+K +G   +  II  ++ LY PL+F LK+  V
Sbjct:   96 HVGLMFGSKALVQLLVNPWIGPLTNRIGYTMPMFGGFVIMFCSTILFAFGDSYFTLWLARALQGVGSACTSTSGMGMLAQAYPDDLERGSAMGIALGGLALGVLVGPPYGGLLYQWSGKELPFVLLALLALF----------DGSIQFMVLQPKIDRGEP------------------------------EGSSIKQLAKDPYIIVAAGAITIGNLGIAMLEPSLPLWMMESWGANSLERGAAFLPASISYLIGTNIFGPLAHRIGRWLSSFIGLVVIGFSLLSIPSATSVAGLIIPH-ALLGFSIGMIDAS-----MF--PLMGYLVDIRHVGVYGSIYAIADAAFCFAFALGPFFSGPLVKSLGFPTMMYIIAVISFLYAPLMFLLKNPPV 440

[Close]

BLAST of slc18a-5 vs. Ensembl Celegans
Match: cat-1 (pep chromosome:WBcel235:X:5705719:5710625:-1 gene:WBGene00000295.1 transcript:W01C8.6a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cat-1)

HSP 1 Score: 78.9518 bits (193), Expect = 2.457e-15
Identity = 89/393 (22.65%), Postives = 166/393 (42.24%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLL-DPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGF-ILGNILNTKLQNRRHYV-LVVILF----VNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 1440
             + +++G+K + Q++V+  IG + +RIG    +  G ++   + +L+  G  YF L L R  +G+ S     S    +A  +     RG   G     + L   VGP YGG +YQ+  K L F+L+ +   F          +  +   V + K+                                   +GS I+ L  DPY ++A  +  +  +   +L  +LP ++ + +G    ++G  +   ++ YL+G  I G + +   +    ++ LVVI F    + S TSV    +P+  +  F + +I        MF  P++  + + +H   YG +  +         ++       L+K +G   +  II  ++ LY PL+F LK+  V
Sbjct:  159 HVGLMFGSKALVQLLVNPWIGPLTNRIGYTMPMFGGFVIMFCSTILFAFGDSYFTLWLARALQGVGSACTSTSGMGMLAQAYPDDLERGSAMGIALGGLALGVLVGPPYGGLLYQWSGKELPFVLLALLALF----------DGSIQFMVLQPKIDRGEP------------------------------EGSSIKQLAKDPYIIVAAGAITIGNLGIAMLEPSLPLWMMESWGANSLERGAAFLPASISYLIGTNIFGPLAHRIGRWLSSFIGLVVIGFSLLSIPSATSVAGLIIPH-ALLGFSIGMIDAS-----MF--PLMGYLVDIRHVGVYGSIYAIADAAFCFAFALGPFFSGPLVKSLGFPTMMYIIAVISFLYAPLMFLLKNPPV 503

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BLAST of slc18a-5 vs. Ensembl Celegans
Match: unc-17 (Vesicular acetylcholine transporter unc-17 [Source:UniProtKB/Swiss-Prot;Acc:P34711])

HSP 1 Score: 56.225 bits (134), Expect = 3.367e-8
Identity = 32/126 (25.40%), Postives = 60/126 (47.62%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLI 660
            +L  L+ +K + Q+ V+   G+I+DR+G    +++G+     +  ++ +G  Y VL+  R  +G  S     S  A IA +F  ++ R    G     +     V P +G  +Y    K + FL++
Sbjct:  101 ELGWLFASKALLQIFVNPFSGYIIDRVGYEIPMILGLCTMFFSTAIFALGKSYGVLLFARSLQGFGSAFADTSGLAMIADRFTEENERSAALGIALAFISFGCLVAPPFGSVLYSLAGKPVPFLIL 226

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BLAST of slc18a-5 vs. Ensembl Fly
Match: VAChT (gene:FBgn0270928 transcript:FBtr0083671)

HSP 1 Score: 80.4925 bits (197), Expect = 9.167e-16
Identity = 100/476 (21.01%), Postives = 195/476 (40.97%), Query Frame = 1

Query:   49 STRDVTEILLQFFSNYSQMNRRLEFILIIYCVGSGKFCLEFITSMV-TPIFPSVIFKWQNLSSFNSS-------DNVSG------FDKFDY-SQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
              R+V +I+ +       +N+R   IL+I  +      L+ +  MV  PI P  +   + + SF+         DN++G       D     S   IL+ +K I Q++V+   G ++D+IG    ++IG+ +   +  ++  GS Y VL   R  +G  S     +  A IA +F  ++ R +  G     +     V P +GG +YQ+  K + FL++          L+ LL    L++ +K  K     S  ++  V                            R L+DPY  +   +  +  +    L  T+  +++       ++ G++W      ++LG ++   +  K    +  +    L +  F+  I+     + M   P+C+I     + D    P L  + + ++   YG +  +     SI  ++   +   +++ IG   LN +I   NL Y+P++  L++
Sbjct:   12 EVREVKDIVWEKIQE--PVNQR-RLILVIVSIA---LLLDNMLYMVIVPIIPDYL---REIGSFDDGPTPPPLRDNITGKIIPVHHDHHGQDSATGILFASKAIVQLMVNPFSGGLIDKIGYDLPMMIGLTIMFFSTAVFACGSSYSVLFFARSLQGAGSAFADTAGLAMIADRFTEENERSQALGIALAFISFGCLVAPPFGGALYQFAGKEVPFLILA---------LVCLLDGLMLLLVMKPVKEAMKQSKDVQDQVIPIW------------------------RLLMDPYIAVCAGALTMSNVALAFLEPTISLWMEDNMTTDNWKIGMVWLPAFFPHVLGVVITVKMARKYPQHQWLMAAGGLALEGFSCFIIPFCSGYKMLMLPICVICFGIALIDTALLPTLGYLVDVRYVSVYGSIYAIADISYSIAYAVGPIIAGGVVEAIGFTALNFLIAFSNLAYVPVLRKLRN 445

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BLAST of slc18a-5 vs. Ensembl Fly
Match: Vmat (gene:FBgn0260964 transcript:FBtr0310062)

HSP 1 Score: 68.1662 bits (165), Expect = 9.346e-12
Identity = 59/265 (22.26%), Postives = 110/265 (41.51%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFL-LILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
            ++ +L+ +K   Q++V+  +G +  RIG    +  G ++  ++ +++  G  Y VL + R  +GI S+    S    +A +F     RG   G     + L   +GP +GG +Y++  K+  FL L  + +   L+ L +L        +   +K  T+                                  S    + DPY LIA  +     M   +L  +LP ++    G T ++QG+ +   ++ YL+G  L   L  K+
Sbjct:  238 EVGLLFASKAFVQLLVNPIVGPLTHRIGYSIPMFAGFVIMFLSTIIFAFGRSYLVLFVARALQGIGSSCSSVSGMGMLADRFTDDKERGNAMGIALGGLALGVLIGPPFGGVMYEFVGKSAPFLILAALALGDGLLQLFML--------QPSIQKAETEPP--------------------------------SLKSLISDPYILIAAGAITFANMGIAMLEPSLPLWMVDNMGATRWEQGVAFLPASISYLIGTNLFGPLGHKI 462

[Close]

BLAST of slc18a-5 vs. Ensembl Fly
Match: Vmat (gene:FBgn0260964 transcript:FBtr0091491)

HSP 1 Score: 68.1662 bits (165), Expect = 9.346e-12
Identity = 59/265 (22.26%), Postives = 110/265 (41.51%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFL-LILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
            ++ +L+ +K   Q++V+  +G +  RIG    +  G ++  ++ +++  G  Y VL + R  +GI S+    S    +A +F     RG   G     + L   +GP +GG +Y++  K+  FL L  + +   L+ L +L        +   +K  T+                                  S    + DPY LIA  +     M   +L  +LP ++    G T ++QG+ +   ++ YL+G  L   L  K+
Sbjct:  238 EVGLLFASKAFVQLLVNPIVGPLTHRIGYSIPMFAGFVIMFLSTIIFAFGRSYLVLFVARALQGIGSSCSSVSGMGMLADRFTDDKERGNAMGIALGGLALGVLIGPPFGGVMYEFVGKSAPFLILAALALGDGLLQLFML--------QPSIQKAETEPP--------------------------------SLKSLISDPYILIAAGAITFANMGIAMLEPSLPLWMVDNMGATRWEQGVAFLPASISYLIGTNLFGPLGHKI 462

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BLAST of slc18a-5 vs. Ensembl Fly
Match: Vmat (gene:FBgn0260964 transcript:FBtr0091493)

HSP 1 Score: 68.1662 bits (165), Expect = 9.346e-12
Identity = 59/265 (22.26%), Postives = 110/265 (41.51%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFL-LILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
            ++ +L+ +K   Q++V+  +G +  RIG    +  G ++  ++ +++  G  Y VL + R  +GI S+    S    +A +F     RG   G     + L   +GP +GG +Y++  K+  FL L  + +   L+ L +L        +   +K  T+                                  S    + DPY LIA  +     M   +L  +LP ++    G T ++QG+ +   ++ YL+G  L   L  K+
Sbjct:  238 EVGLLFASKAFVQLLVNPIVGPLTHRIGYSIPMFAGFVIMFLSTIIFAFGRSYLVLFVARALQGIGSSCSSVSGMGMLADRFTDDKERGNAMGIALGGLALGVLIGPPFGGVMYEFVGKSAPFLILAALALGDGLLQLFML--------QPSIQKAETEPP--------------------------------SLKSLISDPYILIAAGAITFANMGIAMLEPSLPLWMVDNMGATRWEQGVAFLPASISYLIGTNLFGPLGHKI 462

[Close]

BLAST of slc18a-5 vs. Ensembl Fly
Match: Vmat (gene:FBgn0260964 transcript:FBtr0091492)

HSP 1 Score: 67.781 bits (164), Expect = 1.016e-11
Identity = 59/265 (22.26%), Postives = 110/265 (41.51%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFL-LILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
            ++ +L+ +K   Q++V+  +G +  RIG    +  G ++  ++ +++  G  Y VL + R  +GI S+    S    +A +F     RG   G     + L   +GP +GG +Y++  K+  FL L  + +   L+ L +L        +   +K  T+                                  S    + DPY LIA  +     M   +L  +LP ++    G T ++QG+ +   ++ YL+G  L   L  K+
Sbjct:  238 EVGLLFASKAFVQLLVNPIVGPLTHRIGYSIPMFAGFVIMFLSTIIFAFGRSYLVLFVARALQGIGSSCSSVSGMGMLADRFTDDKERGNAMGIALGGLALGVLIGPPFGGVMYEFVGKSAPFLILAALALGDGLLQLFML--------QPSIQKAETEPP--------------------------------SLKSLISDPYILIAAGAITFANMGIAMLEPSLPLWMVDNMGATRWEQGVAFLPASISYLIGTNLFGPLGHKI 462

[Close]

BLAST of slc18a-5 vs. Ensembl Zebrafish
Match: slc18a3a (solute carrier family 18 member 3a [Source:NCBI gene;Acc:559347])

HSP 1 Score: 91.6633 bits (226), Expect = 3.153e-19
Identity = 96/469 (20.47%), Postives = 192/469 (40.94%), Query Frame = 1

Query:   58 DVTEILLQFFSNYSQMNRRLEFILIIYCVGSGKFCLEFITSMV-TPIFPSVIFKWQNLSS-----FNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFL-LILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 1440
            ++ E   Q  +      R+   IL+I CV      L+ +  MV  PI P  +   ++ S       NSS N++  + FD  Q+ +L+ +K I Q++V+   G  +DR+G    LLIG+ +  V+  ++     Y  L + R  +G+ S     S  A IA K+  +  R +  G     +       P +GG +Y++  K   F+ L  + +   ++ L +L   K    + +E                                    M  G+ I + ++DPY  +   +     +    L  T+  ++++    +++Q G+ W      ++LG  L   L  K  + + +   + + +   +S IV A   +     P+C +     + D    P L+ + + +H   YG +  +      +  ++   +   ++  +G  +LN+ +   N+LY P +  L++ S+
Sbjct:   19 EMGERTKQLGNAIQDPERQRRIILVIVCVA---LLLDNMLYMVIVPIVPDYLAHLESESEQAHVKGNSSINITQNENFDL-QIGVLFASKAILQLLVNPLTGTFIDRVGYDIPLLIGLSIMFVSTCIFAFAENYATLFMARSLQGLGSAFADTSGIAMIADKYAEESERSRALGIALAFISFGSLAAPPFGGVLYEFAGKRFPFIALACVCLADGILCLTVL---KPFSSRTREN-----------------------------------MPVGTPIYKLMIDPYIAVVAGALTTCNIPLAFLEPTIANWMEETMNASQWQIGITWLPAFFPHILGVYLTVKLAAKYPHLQWFYGALGMVIIGASSCIVPACKNFEQLIIPLCGVCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYCVAYALGPIVAGKIVHDLGFVQLNLGMGLANVLYAPALLLLRNVSL 445

[Close]

BLAST of slc18a-5 vs. Ensembl Zebrafish
Match: SLC18A1 (solute carrier family 18 member A1 [Source:NCBI gene;Acc:571483])

HSP 1 Score: 69.707 bits (169), Expect = 3.171e-12
Identity = 87/415 (20.96%), Postives = 171/415 (41.20%), Query Frame = 1

Query:  202 SVIFKWQNLSSFNSSDNVSGFDKFDYSQ-----LSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            SV   + N SS +S++   G +  D+ +     + +L+ +K + Q++V+  +G + +RIG    +  G ++  V+ +++     Y +L   R  +GI S+    +    +A  +     RG   G     + +   +G  +G  +Y++ SK+  FL++            + + +  L + + +   ++  S                            M        L DPY LI+  S     M   +L  TLP ++ +     ++Q G+ +   +V YL+G  L  IL  K+   R    +V +F+   + + V      +    P   +     + D     I+  + + +H   YG +  +      +  ++  S G  L++ IG   L +II  +N+LY PL FFLK+
Sbjct:  111 SVSLNFTNFSSASSTNENLGVNNSDFLEGENVKVGLLFASKAMVQLLVNPFVGPLTNRIGYHIPMFAGFVIMFVSTIMFAFSGTYTLLFFARSLQGIGSSFSTVAGLGMLASVYTDDSERGIAMGIALGGLAMGVLIGAPFGSIMYEFVSKSSPFLVL----------AFLAMFDGALQLCILQPSKISPTS----------------------------MEGTPLFILLKDPYILISAGSLCFANMGVAVLEPTLPIWMMQTMCAPKWQLGVAFLPASVSYLIGTNLFGILANKMG--RWLCSMVGMFIVGISLLCVPFAKNLYGLIGPNGGLGFAVGMVDTSMFAIMGYLVDIRHVSVYGSVYAIADVALCVGFAVGPSTGGALVRTIGFPNLMVIIGIINILYAPLCFFLKN 485

[Close]

BLAST of slc18a-5 vs. Ensembl Zebrafish
Match: slc18a2 (solute carrier family 18 member 2 [Source:ZFIN;Acc:ZDB-GENE-080514-1])

HSP 1 Score: 66.6254 bits (161), Expect = 2.575e-11
Identity = 63/285 (22.11%), Postives = 119/285 (41.75%), Query Frame = 1

Query:  226 LSSFNSSDNVSGFDKF--DYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
            +S  N SD     D+   +  ++ +L+ +K   Q+I +  IG + +RIG    +  G  +  V+ +++   S Y +L L R  +G+ S+    +    +A  +   + RG   G     + +   VGP +G  +Y++  KT  FL++ +        L +L   +R+ I      L + +S+   T                           S I  + DPY LIA  S     M   +L   LP ++ +     ++Q G+ +   ++ YL+G  +  +L  K+
Sbjct:   99 VSPQNQSDCPKADDQLLNENVKVGLLFASKATVQLITNPFIGPLTNRIGYQIPMFAGFCIMFVSTIMFAFSSSYTLLFLARSLQGVGSSCSSVAGMGMLASVYTDDEERGNAIGIALGGLAMGVLVGPPFGSVMYEFVGKTAPFLILAV--------LAVLDGGERINIC----SLKSQDSSQKGT---------------------------SLITLMKDPYILIAAGSICFANMAIAMLEPALPIWMMETMCPRKWQLGIAFVPASISYLIGTNIFAVLAHKM 344

[Close]

BLAST of slc18a-5 vs. Ensembl Zebrafish
Match: slc18a2 (solute carrier family 18 member 2 [Source:ZFIN;Acc:ZDB-GENE-080514-1])

HSP 1 Score: 65.4698 bits (158), Expect = 6.654e-11
Identity = 60/285 (21.05%), Postives = 117/285 (41.05%), Query Frame = 1

Query:  226 LSSFNSSDNVSGFDKF--DYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
            +S  N SD     D+   +  ++ +L+ +K   Q+I +  IG + +RIG    +  G  +  V+ +++   S Y +L L R  +G+ S+    +    +A  +   + RG   G     + +   VGP +G  +Y++  KT  FL++           ++ +++  L + V +   V   S    +L                            I  + DPY LIA  S     M   +L   LP ++ +     ++Q G+ +   ++ YL+G  +  +L  K+
Sbjct:  157 VSPQNQSDCPKADDQLLNENVKVGLLFASKATVQLITNPFIGPLTNRIGYQIPMFAGFCIMFVSTIMFAFSSSYTLLFLARSLQGVGSSCSSVAGMGMLASVYTDDEERGNAIGIALGGLAMGVLVGPPFGSVMYEFVGKTAPFLIL----------AVLAVLDGALQLFVLQPSKVEPESQKGTSL----------------------------ITLMKDPYILIAAGSICFANMAIAMLEPALPIWMMETMCPRKWQLGIAFVPASISYLIGTNIFAVLAHKM 403

[Close]

BLAST of slc18a-5 vs. Ensembl Zebrafish
Match: SLC18A1 (solute carrier family 18 member A1 [Source:NCBI gene;Acc:571483])

HSP 1 Score: 65.4698 bits (158), Expect = 6.783e-11
Identity = 88/425 (20.71%), Postives = 171/425 (40.24%), Query Frame = 1

Query:  202 SVIFKWQNLSSFNSSDNVSGFDK--FDYS-------------QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            SV   + N SS +S++   G +    DY              ++ +L+ +K + Q++V+  +G + +RIG    +  G ++  V+ +++     Y +L   R  +GI S+    +    +A  +     RG   G     + +   +G  +G  +Y++ SK+  FL++            + + +  L + + +   ++  S                            M        L DPY LI+  S     M   +L  TLP ++ +     ++Q G+ +   +V YL+G  L  IL  K+   R    +V +F+   + + V      +    P   +     + D     I+  + + +H   YG +  +      +  ++  S G  L++ IG   L +II  +N+LY PL FFLK+
Sbjct:   85 SVSLNFTNFSSASSTNENLGVNSSSADYGCKEDSDFLEGENVKVGLLFASKAMVQLLVNPFVGPLTNRIGYHIPMFAGFVIMFVSTIMFAFSGTYTLLFFARSLQGIGSSFSTVAGLGMLASVYTDDSERGIAMGIALGGLAMGVLIGAPFGSIMYEFVSKSSPFLVL----------AFLAMFDGALQLCILQPSKISPTS----------------------------MEGTPLFILLKDPYILISAGSLCFANMGVAVLEPTLPIWMMQTMCAPKWQLGVAFLPASVSYLIGTNLFGILANKMG--RWLCSMVGMFIVGISLLCVPFAKNLYGLIGPNGGLGFAVGMVDTSMFAIMGYLVDIRHVSVYGSVYAIADVALCVGFAVGPSTGGALVRTIGFPNLMVIIGIINILYAPLCFFLKN 469

[Close]

BLAST of slc18a-5 vs. Ensembl Xenopus
Match: slc18a3 (solute carrier family 18 (vesicular acetylcholine transporter), member 3 [Source:NCBI gene;Acc:780320])

HSP 1 Score: 87.0409 bits (214), Expect = 1.473e-17
Identity = 101/465 (21.72%), Postives = 188/465 (40.43%), Query Frame = 1

Query:   79 QFFSNYSQMNRRLEFILIIYCVGSGKFCLEFITSMVTPIFPSVI----FKWQNLSSFNSSD---NVSGFDKFDYS------QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            Q  +   + + +   ILII CV    F    +  ++ PI P  I       ++  S NSS    N S   +  Y       Q+ +L+ +K I Q++++   G  +DR+G    LLIG+++   + V++     Y  L + R  +G+ S     S  A IA  +  +  R K  G     +     V P +GG +YQ+  K + FL++    +  LI  ++LL    L+IK    +   +                              M  G+ I R ++DPY  +   +     +    L  T+  ++K     +E+Q GL W      ++LG  +   L     + + +   + + +   +S  V A   +W    P+C I     + D    P L+ + + +H   YG +  +      +  ++   +   ++   G  +LN+ +   N+LY P + FL++
Sbjct:   27 QIGTAIKEPHHQRRIILIIVCVA--LFLDNMLYMVIVPIIPDYIQNLRADREHAKSINSSSQYRNKSFAIRPQYPAENEDMQIGVLFASKAILQLLINPLSGTFIDRVGYDIPLLIGLVVLFFSTVIFAFAENYATLFVARSLQGLGSAFADTSGIAMIADTYTEEAERSKALGIALAFISFGSLVAPPFGGILYQFVGKRMPFLVL---ASIALIDGVLLL----LVIKPFTNRTRAN------------------------------MPIGTPIHRLMIDPYIAVVAGALTTCNIPLAFLEPTIANWMKTTMDASEWQMGLTWLPAFFPHVLGVYITVKLAANYPHYQWFYGAIGMVIIGASSCTVPACKNFWELIVPLCGICFGIALVDTALLPTLALLVDVRHVSVYGSVYAIADISYCVAYALGPVVASQIVHTTGFTQLNLGMGLANVLYAPALLFLRN 452

[Close]

BLAST of slc18a-5 vs. Ensembl Xenopus
Match: ddx42 (DEAD-box helicase 42 [Source:Xenbase;Acc:XB-GENE-972670])

HSP 1 Score: 59.3066 bits (142), Expect = 8.267e-9
Identity = 79/386 (20.47%), Postives = 152/386 (39.38%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFH-LIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIV--CAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            ++ +L   K   Q++ +  +G +V RIG    +  G ++  V+ +L+   + Y +L + R F+GI S+         +A  F     RGK  G     + +    GP +G  +Y++  K+  FL I        ++ L IL   +   + V                                           Y   L+DPY L+A     +  +T+ +L  TLP  + +      +Q GL +    V Y   FI  N+     Q    ++ +++  +    SVI    A+  +++   P   +   F + +    P+++ + + +H   YG +  +      I  ++    G  + K +G   L II+  +NL++ PL   L++
Sbjct:  118 RVGLLLAIKAFLQLLFNPIVGKLVTRIGYDAPMFFGFVIVVVSTLLFAFANSYALLCVARGFQGIGSSFTMVPALGTLAQVFPDDVERGKAMGLAMSGVAIGVLAGPPFGSAMYEFVGKSAPFLAIAALALLDGVLQLCILRPTRFSTVDVPATP---------------------------------------YKNLLMDPYILVAAVGLCICNLTFGMLETTLPIRMMETMCAPRYQLGLCFLPCIVAY---FICLNVFAELAQKIGRWLCIMLGMLILGISVICMPLALNIYYLIG-PSAALGIGFGMMETSVMPLMAHLVDLRHTSNYGGIYAISDIALCIGYALGPLCGGAIAKAVGFKWLMIILGIINLVFAPLFILLRN 460

[Close]

BLAST of slc18a-5 vs. Ensembl Xenopus
Match: ddx42 (DEAD-box helicase 42 [Source:Xenbase;Acc:XB-GENE-972670])

HSP 1 Score: 58.5362 bits (140), Expect = 1.229e-8
Identity = 79/406 (19.46%), Postives = 161/406 (39.66%), Query Frame = 1

Query:  238 NSSDNVSGFDKFDY-SQLSILYG----TKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFH-LIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIV--CAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            ++ +    +++ DY ++ ++L G     K + Q++ +  +G I++R G    L  G ++  ++ +++     Y  L + R  +GI S+         +A+ F     RGK  G     + +    GP +G  +Y++  K+  FL I        ++ L IL   +   + V                                           Y   L+DPY L+A     +  +T+ +L  TLP  + +      +Q GL +    V Y   FI  N+     Q    ++ +++  +    SVI    A+  +++   P   +   F + +    P+++ + + +H   YG +  +      I  ++    G  + K +G   L II+  +NL++ PL   L++
Sbjct:   50 SAGNQTQCYEEKDYLNEENVLVGLLLAIKALLQLLTNPIVGKIINRTGYDAPLFCGTIIMFLSTLMFAFADSYAFLCVARGLQGIGSSFTAVPALGMLAHVFPDDAERGKAMGIALSGVAIGVLAGPPFGSAMYEFVGKSAPFLAIAALALLDGVLQLCILRPTRFSTVDVPATP---------------------------------------YKNLLMDPYILVAAVGLCICNLTFGMLETTLPIRMMETMCAPRYQLGLCFLPCIVAY---FICLNVFAELAQKIGRWLCIMLGMLILGISVICMPLALNIYYLIG-PSAALGIGFGMMETSVMPLMAHLVDLRHTSNYGGIYAISDIALCIGYALGPLCGGAIAKAVGFKWLMIILGIINLVFAPLFILLRN 412

[Close]

BLAST of slc18a-5 vs. Ensembl Xenopus
Match: ddx42 (DEAD-box helicase 42 [Source:Xenbase;Acc:XB-GENE-972670])

HSP 1 Score: 53.1434 bits (126), Expect = 7.268e-7
Identity = 41/161 (25.47%), Postives = 73/161 (45.34%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKE---RKLVTD 756
            ++ +L   K   Q++ +  +G +V RIG    +  G ++  V+ +L+   + Y +L + R F+GI S+         +A  F     RGK  G     + +    GP +G  +Y++  K+  FL+I           + LL   + I+ V E   R L+TD
Sbjct:  118 RVGLLLAIKAFLQLLFNPIVGKLVTRIGYDAPMFFGFVIVVVSTLLFAFANSYALLCVARGFQGIGSSFTMVPALGTLAQVFPDDVERGKAMGLAMSGVAIGVLAGPPFGSAMYEFVGKSSPFLVIAA---------LALLDGGKKILHVPETPYRVLLTD 269

[Close]

BLAST of slc18a-5 vs. Ensembl Xenopus
Match: ddx42 (DEAD-box helicase 42 [Source:Xenbase;Acc:XB-GENE-972670])

HSP 1 Score: 52.7582 bits (125), Expect = 7.680e-7
Identity = 41/161 (25.47%), Postives = 73/161 (45.34%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKE---RKLVTD 756
            ++ +L   K   Q++ +  +G +V RIG    +  G ++  V+ +L+   + Y +L + R F+GI S+         +A  F     RGK  G     + +    GP +G  +Y++  K+  FL+I           + LL   + I+ V E   R L+TD
Sbjct:   96 RVGLLLAIKAFLQLLFNPIVGKLVTRIGYDAPMFFGFVIVVVSTLLFAFANSYALLCVARGFQGIGSSFTMVPALGTLAQVFPDDVERGKAMGLAMSGVAIGVLAGPPFGSAMYEFVGKSSPFLVIAA---------LALLDGGKKILHVPETPYRVLLTD 247

[Close]

BLAST of slc18a-5 vs. Ensembl Mouse
Match: Slc18a3 (solute carrier family 18 (vesicular monoamine), member 3 [Source:MGI Symbol;Acc:MGI:1101061])

HSP 1 Score: 69.707 bits (169), Expect = 3.245e-12
Identity = 73/334 (21.86%), Postives = 133/334 (39.82%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGS-VGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKER-KLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKM 1278
            ++ +L+ +K I Q++V+   G  +DR+     LLIG+ +   + V++     Y  L   R  +G+ S     S  A IA K+  +  R +  G V+L     GS V P +GG +Y++  K + FL++     F    L++L V K      + R  L      H                                 R +LDPY  +   +     +    L  T+  ++K     +E++ G++W    V ++LG  L   L  +  + +     + L V   +S +V A   +      +C +     + D    P L+ + + +H   YG +
Sbjct:  123 KIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVMFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALG-VALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDA--LLLLAVAKPFSAAARARANLPVGTPIH---------------------------------RLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMVWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGVSSCVVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV 420

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BLAST of slc18a-5 vs. Ensembl Mouse
Match: Slc18a2 (solute carrier family 18 (vesicular monoamine), member 2 [Source:MGI Symbol;Acc:MGI:106677])

HSP 1 Score: 56.6102 bits (135), Expect = 5.045e-8
Identity = 58/265 (21.89%), Postives = 111/265 (41.89%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLL-DPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
            Q+ +L+ +K   Q++ +  IG + +RIG    +  G  +  ++ V++   S Y  L++ R  +GI S+    +    +A  +   + RG   G     + +   VGP +G  +Y++  KT  FL++            ++L++  + + V +   V   S                              KG+ +  LL DPY LIA  S     M   +L   LP ++ +     ++Q G+ +   ++ YL+G  +  IL  K+
Sbjct:  133 QVGLLFASKATVQLLTNPFIGLLTNRIGYPIPMFAGFCIMFISTVMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNAMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVL----------AALVLLDGAIQLFVLQPSRVQPES-----------------------------QKGTPLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKM 358

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BLAST of slc18a-5 vs. UniProt/SwissProt
Match: sp|Q08C75|VACHA_DANRE (Probable vesicular acetylcholine transporter-A OS=Danio rerio OX=7955 GN=slc18a3a PE=2 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 2.380e-18
Identity = 96/469 (20.47%), Postives = 192/469 (40.94%), Query Frame = 1

Query:   58 DVTEILLQFFSNYSQMNRRLEFILIIYCVGSGKFCLEFITSMV-TPIFPSVIFKWQNLSS-----FNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFL-LILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 1440
            ++ E   Q  +      R+   IL+I CV      L+ +  MV  PI P  +   ++ S       NSS N++  + FD  Q+ +L+ +K I Q++V+   G  +DR+G    LLIG+ +  V+  ++     Y  L + R  +G+ S     S  A IA K+  +  R +  G     +       P +GG +Y++  K   F+ L  + +   ++ L +L   K    + +E                                    M  G+ I + ++DPY  +   +     +    L  T+  ++++    +++Q G+ W      ++LG  L   L  K  + + +   + + +   +S IV A   +     P+C +     + D    P L+ + + +H   YG +  +      +  ++   +   ++  +G  +LN+ +   N+LY P +  L++ S+
Sbjct:   19 EMGERTKQLGNAIQDPERQRRIILVIVCVA---LLLDNMLYMVIVPIVPDYLAHLESESEQAHVKGNSSINITQNENFDL-QIGVLFASKAILQLLVNPLTGTFIDRVGYDIPLLIGLSIMFVSTCIFAFAENYATLFMARSLQGLGSAFADTSGIAMIADKYAEESERSRALGIALAFISFGSLAAPPFGGVLYEFAGKRFPFIALACVCLADGILCLTVL---KPFSSRTREN-----------------------------------MPVGTPIYKLMIDPYIAVVAGALTTCNIPLAFLEPTIANWMEETMNASQWQIGITWLPAFFPHILGVYLTVKLAAKYPHLQWFYGALGMVIIGASSCIVPACKNFEQLIIPLCGVCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYCVAYALGPIVAGKIVHDLGFVQLNLGMGLANVLYAPALLLLRNVSL 445

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BLAST of slc18a-5 vs. UniProt/SwissProt
Match: sp|P59845|VACHB_DANRE (Probable vesicular acetylcholine transporter-B OS=Danio rerio OX=7955 GN=slc18a3b PE=2 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 1.872e-17
Identity = 85/417 (20.38%), Postives = 174/417 (41.73%), Query Frame = 1

Query:  181 MVTPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLK 1428
            ++ PI P  +   +     +S+D        D  Q+ +L+ +K + Q++V+   G  +DR+G    LLIG+++  ++  ++     Y  L   R  +G+ S     S  A IA KF  +  R +  G     +     V P +GG +Y++  K + F+++            + L +  L++ V   K  +D +                            M  G+ I R ++DPY  +   +  V  +    L  T+  +++     +++Q GL+W    + ++LG  +   L  +   R+ +   + + +   +S  V A   +    FP+C I     + D    P L+ + + +H   YG +  +     S+  ++   +   ++  +G  +LN+ +  VN+LY P +  L+
Sbjct:   58 VIVPIIPDYLADLRGERGNSSAD-------LDI-QIGVLFASKALLQLLVNPLSGTFIDRVGYDLPLLIGLLVMFLSTCIFAFAENYGTLFAARSLQGLGSAFADTSGIAMIADKFTEEAERSRALGIALAFISFGSLVAPPFGGILYEFAGKRVPFIVL----------ACVCLADGVLLLTVV--KPFSDRTREN-------------------------MPVGTPIHRLMVDPYIAVVAGALTVCNIPLAFLEPTIANWMESTMDASKWQMGLVWLPAFLPHVLGVYITVRLAARYPERQWFYGALGMVIIGASSCTVPACKTFGELVFPLCGICFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYAMGPVVAGQIVHNLGFVQLNLGMGLVNVLYAPALLLLR 429

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BLAST of slc18a-5 vs. UniProt/SwissProt
Match: sp|P81721|VACHT_TETCF (Vesicular acetylcholine transporter OS=Tetronarce californica OX=7787 PE=2 SV=2)

HSP 1 Score: 85.5001 bits (210), Expect = 1.870e-16
Identity = 81/384 (21.09%), Postives = 160/384 (41.67%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            Q+ +L+ +K I Q++ +   G  +DR+G    LLIG+ +   + + +  G  Y VL   R  +G+ S     S  A IA K+  +  R +  G     +     V P +GG +YQ+  K + FL  ++     L  +++L+V      + +E  L                                   +G+ I + ++DPY  +   +     +    L  T+  ++KK    +E+Q G+ W      ++LG  +   L  K  N + +   V L +   +S  + A   +     P+C +     + D    P L+ + + ++   YG +  +     S+  ++   +   ++  +G  +LN+ +  VN+LY P + FL++
Sbjct:  110 QIGVLFASKAILQLLSNPFTGTFIDRVGYDIPLLIGLTIMFFSTITFAFGESYAVLFAARSLQGLGSAFADTSGIAMIADKYTEESERTQALGIALAFISFGSLVAPPFGGVLYQFAGKWVPFL--VLSFVCLLDGILLLMVVTPFASRTRENML-----------------------------------QGTPIYKLMIDPYIAVVAGALTTCNIPLAFLEPTISNWMKKTMNASEWQMGITWLPAFFPHILGVYITVKLAAKYPNYQWFYGAVGLVIIGASSCTIPACRNFEELIIPLCALCFGIALVDTALLPTLAFLVDIRYVSVYGSVYAIADISYSVAYALGPIMAGQIVHDLGFVQLNLGMGLVNILYAPALLFLRN 456

[Close]

BLAST of slc18a-5 vs. UniProt/SwissProt
Match: sp|O17444|VACHT_DROME (Vesicular acetylcholine transporter OS=Drosophila melanogaster OX=7227 GN=VAChT PE=2 SV=2)

HSP 1 Score: 80.4925 bits (197), Expect = 9.189e-15
Identity = 100/476 (21.01%), Postives = 195/476 (40.97%), Query Frame = 1

Query:   49 STRDVTEILLQFFSNYSQMNRRLEFILIIYCVGSGKFCLEFITSMV-TPIFPSVIFKWQNLSSFNSS-------DNVSG------FDKFDY-SQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
              R+V +I+ +       +N+R   IL+I  +      L+ +  MV  PI P  +   + + SF+         DN++G       D     S   IL+ +K I Q++V+   G ++D+IG    ++IG+ +   +  ++  GS Y VL   R  +G  S     +  A IA +F  ++ R +  G     +     V P +GG +YQ+  K + FL++          L+ LL    L++ +K  K     S  ++  V                            R L+DPY  +   +  +  +    L  T+  +++       ++ G++W      ++LG ++   +  K    +  +    L +  F+  I+     + M   P+C+I     + D    P L  + + ++   YG +  +     SI  ++   +   +++ IG   LN +I   NL Y+P++  L++
Sbjct:   12 EVREVKDIVWEKIQE--PVNQR-RLILVIVSIA---LLLDNMLYMVIVPIIPDYL---REIGSFDDGPTPPPLRDNITGKIIPVHHDHHGQDSATGILFASKAIVQLMVNPFSGGLIDKIGYDLPMMIGLTIMFFSTAVFACGSSYSVLFFARSLQGAGSAFADTAGLAMIADRFTEENERSQALGIALAFISFGCLVAPPFGGALYQFAGKEVPFLILA---------LVCLLDGLMLLLVMKPVKEAMKQSKDVQDQVIPIW------------------------RLLMDPYIAVCAGALTMSNVALAFLEPTISLWMEDNMTTDNWKIGMVWLPAFFPHVLGVVITVKMARKYPQHQWLMAAGGLALEGFSCFIIPFCSGYKMLMLPICVICFGIALIDTALLPTLGYLVDVRYVSVYGSIYAIADISYSIAYAVGPIIAGGVVEAIGFTALNFLIAFSNLAYVPVLRKLRN 445

[Close]

BLAST of slc18a-5 vs. UniProt/SwissProt
Match: sp|Q91498|VACHT_TORMA (Vesicular acetylcholine transporter OS=Torpedo marmorata OX=7788 PE=2 SV=2)

HSP 1 Score: 80.1073 bits (196), Expect = 1.114e-14
Identity = 83/384 (21.61%), Postives = 161/384 (41.93%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            Q+ +L+ +K I Q++ +   G  +DR+G    LLIG+ +   + + +  G  Y +L   R  +G+ S     S  A IA K+  +  R +  G     +     V P +GG +YQ+  K + FL++       L+  I+LL+   ++     R  V        TL                        +G+ I + ++DPY  +   +     +    L  T+  ++KK    +E+Q G+ W      ++LG  +   L  K  N +     V L +   +S  + A   +     P+C +     + D    P L+ + + ++   YG +  +     S+  ++   +   ++  +G  +LN+ +  VN+LY P + FL++
Sbjct:  106 QIGVLFASKAILQLLSNPFTGTFIDRVGYDIPLLIGLTIMFFSTITFAFGESYAILFAARSLQGLGSAFADTSGIAMIADKYTEESERTQALGIALAFISFGSLVAPPFGGVLYQFAGKWVPFLVLSF---VCLLDGILLLM---VVTPFASRTRV-------NTL------------------------QGTPIYKLMIDPYIAVVAGALTTCNIPLAFLEPTISNWMKKTMNASEWQMGITWLPAFFPHILGVYITVKLAAKYPNYQWLYGAVGLVIIGASSCTIPACRNFEELIIPLCALCFGIALVDTALLPTLAFLVDIRYVSVYGSVYAIADISYSVAYALGPIMAGQIVHDLGFVQLNLGMGLVNILYAPGLLFLRN 452

[Close]

BLAST of slc18a-5 vs. TrEMBL
Match: A0A0H3YF28 (Slc18a-5 OS=Schmidtea mediterranea OX=79327 GN=slc18a-5 PE=2 SV=1)

HSP 1 Score: 814.298 bits (2102), Expect = 0.000e+0
Identity = 446/446 (100.00%), Postives = 446/446 (100.00%), Query Frame = 1

Query:  103 MNRRLEFILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 1440
            MNRRLEFILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVNSNKNSSSNIANIKENIKSEVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMLTGTSITSSIWSSLGPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV
Sbjct:    1 MNRRLEFILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVNSNKNSSSNIANIKENIKSEVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMLTGTSITSSIWSSLGPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 446

[Close]

BLAST of slc18a-5 vs. TrEMBL
Match: A0A0H3YK86 (Slc18a-3 OS=Schmidtea mediterranea OX=79327 GN=slc18a-3 PE=2 SV=1)

HSP 1 Score: 290.426 bits (742), Expect = 6.121e-89
Identity = 175/476 (36.76%), Postives = 273/476 (57.35%), Query Frame = 1

Query:  124 ILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLS----SFNSSDNVSGFDK-FDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLV----NKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIR------------------------------FLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDF 1434
            +LII+ +   K+ + FIT MV PIFP++I K  N S    + N S  +S  +  F+Y QLSIL+ TKNICQ+++S  +G+   R+G L  L  G+ LQ V+++ YG G+ YF+LI+GRIFE ++S  I C+VS+++AY++      G  +G   L + + G+ GP+YGG+V+QY+ K + FL +L   T   I ++ L++    NK   I+  +  L  + +  +E   ++    S        +    V+   S+                                FL DPYF+I + ++PV++ + ++ YATLP ++K  FG +E QQG+IW L  VGY +GF+LGN LN K    RH VL+V ++V++  ++ +  MP WW  A P+CLI  Q LVF++   P+L+ I  K+H+ ++G MAG+++   ++TSS  S LGPIL  KIG   LNII+  + L+Y PL+  LK F
Sbjct:   10 LLIIFSISLAKYSVGFITGMVIPIFPTLIDKHFNESLPVPAANFSSEISVLNSSFNYQQLSILFATKNICQILLSPWMGYFCGRLGSLNILFSGVGLQTVSILFYGFGNKYFLLIIGRIFEALASGAINCAVSSFVAYRYTDHKKLGLVYGIGGLGLCIGGASGPAYGGWVFQYHGKLMVFLTVLSMTTVEAILILSLMIANKSNKSHHIETIKNPLCAEINEIVENKFDNEIIISMPNNISISSEGVNVLLDNSFKEPKFGSLLNENGNENNHLSVEKSKPEHNIFYFLSDPYFMICLGAFPVMYFSLFVYYATLPHFMKVTFGASESQQGVIWLLNLVGYFIGFLLGNFLNAKFAKSRHIVLMVTVYVHAIGALCISLMPSWWSIAIPLCLIVNQHLVFEIIIAPLLTSIVAKRHESKFGLMAGIIMMAIALTSSCGSFLGPILFSKIGFLYLNIIVAVMGLVYGPLLLMLKQF 485

[Close]

BLAST of slc18a-5 vs. TrEMBL
Match: A4KWG5 (Vesicular acetylcholine transporter OS=Branchiostoma floridae OX=7739 PE=2 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 1.833e-22
Identity = 116/468 (24.79%), Postives = 206/468 (44.02%), Query Frame = 1

Query:   79 QFFSNYSQMNRRLEFILIIYCVGSGKFCLEFITSMV-TPIFPSVIFKW------QNLSSFNSSDNVS-------GFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLI--ILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLI-FTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            +F         + + +L+I C+      L+ +  MV  PI P  +         Q  +++N +DN +       G++  D + +  L+ +K I Q+IV+   G ++DR G  + ++IG+ +  ++  ++  GS Y VL + R  +G+ S     +  A IA +F  +  R K  G     +     V P +GG +YQY  K + FL      T   I L+  ILL    L +   +R+   DN     TLV +                          + L+DPY  IA  +  +  ++   L  T+  ++K+    TE++ G++W    + Y++G  L   L  K  + +  + +V L V   ++ IV     + +   PV  I F + LV      P L+ I + +H   YG +  +     S+  ++   L   ++  +G  +LNI I  VN+LY P++ FLK+
Sbjct:   17 RFMEKIQDPKSQRKLVLVIVCIA---LLLDNMLYMVIVPIIPDYLHSIGAFEPIQEKTAWNGTDNKTYWNTTTVGYENEDIN-IGFLFASKAIVQLIVNPLSGTLIDRTGYEKPMVIGISVMFISTAVFAFGSSYTVLFIARSLQGVGSAFADSAGLAMIADRFTEEGERSKALGIALAFISFGCLVAPPFGGILYQYAGKRVPFL------TLSFICLVDGILL----LFVTRPDRESGKDN-----TLVGTPMW-----------------------KLLIDPYIAIAGGALVMCNVSLAFLEPTIAIWMKETMHSTEWEMGIVWLPCFIPYIVGVCLTVWLAGKYWHYQWLLALVGLVVQGLSTFIVPEATSFAVLILPVAGICFGEALVSTAML-PTLAYIVDVRHTSVYGSIYAIADISYSLAYAMGPMLAGKIMHDLGFLQLNIGIGLVNILYAPVLLFLKN 441

[Close]

BLAST of slc18a-5 vs. TrEMBL
Match: T1EMB8 (MFS domain-containing protein OS=Helobdella robusta OX=6412 GN=20197718 PE=4 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 5.278e-20
Identity = 96/395 (24.30%), Postives = 180/395 (45.57%), Query Frame = 1

Query:  256 SGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLI-LIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVI-LFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            SG +  D +++ IL+ +K + Q+ +S   G ++DRIG    ++IG+ +   +  ++  G  Y +L + R  +G+ S     S  A IA ++K    R K  G     +       P +GGF Y+Y  K + FLL+ LI +   ++   + LV+K    K KE++ + DN                            +  KG+ I + +LDPY  +   +  +  ++   L  T+ R++K+     EFQ G++W    + ++LG  +  +   KL  +  +++  + L +   + +I+     + M   P+ +      + D    P L+ + + +H   YG +  +     S+  +    L   + +KIG F LN  I+  N+LY PL+ FLK+
Sbjct:  100 SGDESTD-ARVGILFASKALVQLFISPISGTVIDRIGYETPMIIGLSIIFFSTTIFAFGRSYALLFIARSLQGVGSAFADTSGLAMIADRYKENAARSKAQGIALAFISFGCLFAPPFGGFFYKYAGKAVPFLLLSLIALADGVM---LKLVSKP--AKKKEKQTLCDNG---------------------------LEKKGTPIYKLILDPYIALCAGALVMANVSLAFLEPTIARWMKETMKADEFQIGVVWLPPFIPHVLGVYV-TVRLAKLYPKHQWLITAVGLSLEGISCLIIPFCSNFKMVILPLMIDCFGIALVDTAILPSLAYLVDHRHVSVYGSVYAIADISYSLAYAFGPILADEIYQKIGFFWLNFGIFLSNVLYAPLLIFLKN 460

[Close]

BLAST of slc18a-5 vs. TrEMBL
Match: A0A4D9E5M6 (5'-AMP-activated protein kinase subunit beta-1 OS=Platysternon megacephalum OX=55544 GN=DR999_PMT11645 PE=4 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.022e-18
Identity = 98/470 (20.85%), Postives = 194/470 (41.28%), Query Frame = 1

Query:   67 EILLQFFSNYSQMNRRLEFILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLSSFNSSDNVSGFD--------------KFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            E   Q  +    ++R+   IL+I CV    F    +  ++ PI PS +  W+   S  S  N  G +              + +  ++ +L+ +K I Q++V+   G  +DR+G    LLIG+ +  ++ +++ +   Y  L   R  +G+ S     S  A IA K+  +  R +  G     +     V P +GG +Y++  + L F L+L  +      L++ ++ K    + +E  LV                                   G+ I R ++DPY  +   +     +    L  T+  ++KK  G +E++ G+ W      ++LG  +   L  K  + + +   + + +   +S  V A   +     P+C I     + D    P L+ + + +H   YG +  +     S+  ++   +   ++  +G  +LN+ +   N+LY P++ FLK+
Sbjct:   23 EKTKQLGTAMQDVHRQRRLILVIVCVA--LFLDNMLYMVIVPIMPSYLAMWEAQESNASGANARGANASWAKSVLGPGYPPENEDIKIGVLFASKAILQLLVNPLSGTFIDRVGYDIPLLIGLTVMFLSTIIFALAENYATLFAARSLQGLGSAFADTSGIAMIADKYTEESERSRALGIALAFISFGSLVAPPFGGILYEFAGRRLPF-LVLASVCLLDGLLLLTVI-KPFGSRARENMLV-----------------------------------GTPIHRLMIDPYIAVVAGALTTCNIPLAFLEPTIATWMKKTMGASEWEMGVTWLPAFFPHVLGVYITVKLAAKYPHLQWFYGALGMVIIGASSCTVPACRNFGQLIVPLCGICFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVASQIVHSLGFVQLNLGMGLANVLYAPVLLFLKN 453

[Close]

BLAST of slc18a-5 vs. Ensembl Cavefish
Match: slc18a3b (solute carrier family 18 member 3b [Source:NCBI gene;Acc:394082])

HSP 1 Score: 73.1738 bits (178), Expect = 1.773e-13
Identity = 91/446 (20.40%), Postives = 178/446 (39.91%), Query Frame = 1

Query:  106 NRRLEFILIIYCVGSGKFCLEFITSMV-TPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQD-NRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI---RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLK 1428
             R+   IL+I CV      L+ +  MV  PI P  +     +S  N           D  ++ +L+ +K I Q+ V+   G  +DR+G    LLIG+M+  ++  ++     Y  L   R  +G+ S     S  A IA ++  ++  R +  G     +     V P +GG +Y+   K + FL++            + L +  L++ V     V   SN                            N+ + +   R ++DPY  +   +  V  +    L  T+  +++     T++Q GL W  +   ++LG  L   L  +  + + +   V + +   +S +V A   +     P+C I     + D    P ++ + + ++   YG +  +     S+  ++       ++  +G  +LN+ +   N+LY P +  L+
Sbjct:   20 KRQRTVILVIVCVA---LLLDNMLYMVIVPIIPDYLAGASPVSKTN----------LDV-KIGVLFASKAILQLAVNPLSGPFIDRVGYDLPLLIGLMVMFMSTCVFAFAETYATLFAARSLQGLGSAFADTSGIAMIADRYGDEETERSRALGLALAFISFGSLVAPPFGGILYELAGKRVPFLVL----------ACVCLADGCLLLAV-----VKPFSNQGAR-----------------------QNQPAGVPLHRLIMDPYIAVVAGALTVCNIPLAFLEPTIAGWMENTMHATKWQIGLAWLPSFFPHVLGVYLTVKLAERYPSMQWFYGAVGMLIIGASSCVVPACKSFSQLMLPLCGICFGIALVDTALLPTMAFLVDVRYASVYGSVYAIADISYSVAYALGPVAAGHIVHTMGFAQLNLGMGLANVLYAPALLALR 413

[Close]

BLAST of slc18a-5 vs. Ensembl Cavefish
Match: slc18a2 (synaptic vesicular amine transporter [Source:NCBI gene;Acc:103032219])

HSP 1 Score: 69.707 bits (169), Expect = 2.782e-12
Identity = 90/409 (22.00%), Postives = 166/409 (40.59%), Query Frame = 1

Query:  241 SSDNVSGFDKFDYS------QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPV-CLIFTQFLV------FDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLK 1428
            S+ N S   K D        ++ +L+ +K   Q+I +  IG + +RIG    +  G  +  ++ +++   S Y +L L R  +G+ S+    +    +A  +   + RG   G     + +   VGP +G  +Y++  KT  FL++           ++ +++  L + V +   V   S    +L                            +  + DPY LIA  S     M   +L   LP ++ +     ++Q G+ +   +V YL+G  +  +L  K+  R    L+ +L V     + +  +P    FA  +  LI   F V       D    PI+  + + +H   YG +  +      +  +   S G  + + IG   L  II  V++L+ PL FFL+
Sbjct:  108 SAPNASNCPKADDQLLNENVKVGLLFASKATVQLITNPFIGPLTNRIGYQIPMFAGFCIMFLSTIMFAFSSSYTLLFLARSMQGVGSSCSSVAGMGMLASVYTDDEERGNAIGIALGGLAMGVLVGPPFGSVMYEFVGKTAPFLIL----------AVLAVLDGALQLFVLQPSKVEPESQKGTSL----------------------------MTLMKDPYILIAAGSICFANMAIAMLEPALPIWMMETMCARKWQLGVAFLPASVSYLIGTNIFAVLANKM-GRWLCALIGMLLVG----ISILCVP----FAKDIYGLILPNFGVGFAIGMVDSSMMPIMGYLVDLRHISVYGSVYAIADVAFCMGFAFGPSAGGAIARSIGFPWLMTIIGIVDILFAPLCFFLR 469

[Close]

BLAST of slc18a-5 vs. Ensembl Cavefish
Match: SLC18A1 (solute carrier family 18 member A1 [Source:NCBI gene;Acc:103028146])

HSP 1 Score: 64.6994 bits (156), Expect = 1.011e-10
Identity = 88/426 (20.66%), Postives = 174/426 (40.85%), Query Frame = 1

Query:  166 EFITSMVTPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFH-LIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 1440
            E  +++  P  PS        +  +  D+    D+ +  ++ +L+ +K + Q++V+  +G + +RIG    +  G ++  V+ +++     Y +L   R  +GI S+    +    +A  +   + RG   G     + +   +G  +G  +Y++  K+  FL++     F   + L IL  +K     V+   L+T                                        L DPY LI+  S     M   IL  TLP ++ +     ++Q G+ +   +V YL+G  L  +L  K+   R    ++ +F+   + + V      +    P   +     + D     I+  + + +H   YG +  +      +  +I  S G  +++ IG   L ++I  VN+LY PL +FLK+ +V
Sbjct:   88 ESPSNLSDPSTPSPPETGLKGNKSDCKDDTEFLDE-ENVRVGLLFASKALVQLLVNPFVGPLTNRIGYHIPMFAGFIIMFVSTIMFAFSGTYALLFFARSLQGIGSSFSSVAGLGMLASVYTDDEERGIAMGIALGGLAMGVLIGAPFGSVMYEFVGKSSPFLILAFLALFDGALQLCILQPSKISPGSVEGTPLLT---------------------------------------LLKDPYILISAGSLCFANMGVAILEPTLPIWMMQTMCSQKWQLGVAFLPASVSYLIGTNLFGLLANKMG--RWLCSMIGMFIVGISLICVPLASNIYGLIGPNGGLGFAIGMVDSSMMAIMGYLVDIRHSSVYGSVYAIADVALCMGFAIGPSTGGAIVRVIGFPYLMVMIGIVNILYAPLCYFLKNPAV 471

[Close]

BLAST of slc18a-5 vs. Ensembl Cavefish
Match: slc18a3a (solute carrier family 18 member A3 [Source:NCBI gene;Acc:103044616])

HSP 1 Score: 59.6918 bits (143), Expect = 4.135e-9
Identity = 80/416 (19.23%), Postives = 159/416 (38.22%), Query Frame = 1

Query:   58 DVTEILLQFFSNYSQMNRRLEFILIIYCVGSGKFCLEFITSMV-TPIFPSVIFKWQNLSSFNSSDNVS-------------GFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFL-LILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKH 1257
            ++ E   Q  +      R+   IL+I CV      L+ +  MV  PI P  + + ++ S    S +V                +  D  Q+ +L+ +K I Q+IV+   G  +DR+G    LLIG+ +  V+  ++     Y  + + R  +G+ S     +  A IA  +  +  R +  G     +       P +GG +YQ+  K + F+ L  + +   ++ L +L   K    + +E                                    M  G  I + ++DPY  +   +     +    L  T+  ++++    +++Q GL W      ++LG  +   L  +  + + +   + + +   +S  V A   +     P+C I     + D    P L+ + + +H
Sbjct:   19 EMGERTKQLGTAIQDPERQRRIILVIVCVA---LLLDNMLYMVIVPIVPDYLARLESQS--EQSHHVVLSNSTNSSSQTNFPAENLDL-QVGVLFASKAILQLIVNPLTGTFIDRVGYDIPLLIGLSIMFVSTCIFAFAENYATMFVARSMQGLGSAFADTAGIAMIADTYTEEAERSRALGIALAFISFGSLAAPPFGGVLYQFAGKRVPFIALACVCLADGILCLTVL---KPFSSRTREN-----------------------------------MPVGPPIYKLMIDPYIAVVAGALTTCNIPLAFLEPTIANWMEETMDSSQWQIGLTWLPAFFPHVLGVYITVKLAAQYPHLQWFYGALGMVIIGASSCTVPACKNFEQLIIPLCGICFGIALVDTALLPTLAFLVDVRH 390

[Close]

BLAST of slc18a-5 vs. Ensembl Cavefish
Match: SLC18A1 (solute carrier family 18 member A1 [Source:NCBI gene;Acc:103028146])

HSP 1 Score: 55.0694 bits (131), Expect = 1.170e-7
Identity = 84/393 (21.37%), Postives = 162/393 (41.22%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIG------DLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFH-LIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 1440
            ++ +L+ +K + Q++V+  +G + +RIG       L T+++ +M   +  +L+     Y +L   R  +GI S+    +    +A  +   + RG   G     + +   +G  +G  +Y++  K+  FL++     F   + L IL  +K     V+   L+T                                        L DPY LI+  S     M   IL  TLP ++ +     ++Q G+ +   +V YL+G  L  +L  K+   R    ++ +F+   + + V      +    P   +     + D     I+  + + +H   YG +  +      +  +I  S G  +++ IG   L ++I  VN+LY PL +FLK+ +V
Sbjct:  129 RVGLLFASKALVQLLVNPFVGPLTNRIGYHIPMFILATVIM-IMFAFIYNILFAFSGTYALLFFARSLQGIGSSFSSVAGLGMLASVYTDDEERGIAMGIALGGLAMGVLIGAPFGSVMYEFVGKSSPFLILAFLALFDGALQLCILQPSKISPGSVEGTPLLT---------------------------------------LLKDPYILISAGSLCFANMGVAILEPTLPIWMMQTMCSQKWQLGVAFLPASVSYLIGTNLFGLLANKMG--RWLCSMIGMFIVGISLICVPLASNIYGLIGPNGGLGFAIGMVDSSMMAIMGYLVDIRHSSVYGSVYAIADVALCMGFAIGPSTGGAIVRVIGFPYLMVMIGIVNILYAPLCYFLKNPAV 479

[Close]

BLAST of slc18a-5 vs. Ensembl Sea Lamprey
Match: slc18a3a (solute carrier family 18 member 3a [Source:NCBI gene;Acc:559347])

HSP 1 Score: 90.8929 bits (224), Expect = 9.249e-20
Identity = 81/389 (20.82%), Postives = 166/389 (42.67%), Query Frame = 1

Query:  265 DKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLK 1428
            D  +  ++ IL+ +K I Q++V+   G  +DR+G    LLIG+ +  ++  ++  G  Y  L   R  +G+ S     +  A IA +F  +  R +  G     +     V P +GG +Y++  K + FL++     F    L++++V K    + +E                                    M +G+ I R ++DPY ++   +  +  +    L  T+  ++KK  G  E+Q+G+ W      ++LG  +   L  K    + +   + L +   +S +V A   +     P+C I     + D    P+L+ + + +H   YG +  +     S+  ++   +   ++  +G  +L++ +   N+LY P++  L+
Sbjct:  110 DADEDIRIGILFASKAIVQLLVNPLTGTFIDRVGYDLPLLIGLSIIFLSTAVFAFGESYATLFAARSLQGLGSAFADTAAIAMIADRFTEEAERSRALGIALAFISFGSLVAPPFGGTLYEFVGKRVPFLVLACVSLFD--GLLLMVVAKPFSSRSREN-----------------------------------MPQGTPIYRLMMDPYIVVVAGALTMANIPLAFLEPTIASWMKKTMGANEWQRGMTWLPAFFPHVLGVYITVKLAAKYPQLQWFYGGLGLVIIGSSSCLVPACRTFEELIAPLCGICFGIALVDTALLPLLAFLVDVRHASVYGSVYAIADISYSLAYAMGPIVAGQIVHTMGFVQLSLGMGLTNVLYAPMLLLLR 461

[Close]

BLAST of slc18a-5 vs. Ensembl Sea Lamprey
Match: slc18a2 (solute carrier family 18 member 2 [Source:ZFIN;Acc:ZDB-GENE-080514-1])

HSP 1 Score: 50.447 bits (119), Expect = 6.719e-7
Identity = 27/126 (21.43%), Postives = 59/126 (46.83%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLI 660
            ++ +L+  K   Q++ +  IG + +R+G    +  G ++  ++ +++     Y +L L R  +GI S+    +    +A  +   + RG   G     + +   VGP +G  +Y +  K   FL++
Sbjct:  150 RVGLLFAAKATVQLLANPFIGPLTNRVGYHSPMFAGFIIMFLSTIMFAFAQSYPLLFLARALQGIGSSCSSVAGMGMLASLYPDDEERGNAMGVALGGLAMGVLVGPPFGSIMYDFVGKPAPFLVL 275

[Close]

BLAST of slc18a-5 vs. Ensembl Medaka
Match: slc18a3b (probable vesicular acetylcholine transporter-B [Source:NCBI gene;Acc:101163117])

HSP 1 Score: 87.0409 bits (214), Expect = 7.565e-18
Identity = 99/467 (21.20%), Postives = 190/467 (40.69%), Query Frame = 1

Query:   79 QFFSNYSQMNRRLEFILIIYCVGSGKFCLEFITSMV-TPIFPSVIFKWQN--------LSSFNSSDNVSGFDKFDYS----QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFS 1437
            Q  +     +++   IL+I CV      L+ +  MV  PI P  +   +N        +   N+S N +  DK + +    Q+ +L+ +K I Q++V+   G  +DR+G    LLIG+ +  ++  ++  G  Y  L   R  +G+ S     S  A IA K+  +  R    G     +     V P +GG +Y++  K + FL++            I L +  L++ V     +   SN                           M  G+ I + ++DPY  +   +  V  +    L  T+  +++     T+++ GL W      ++LG  +   L  K  + + +   + + +   +S  V A   +     P+C I     + D    P L+ + + +H   YG +  +     S+  ++   +   ++  +G  +LN+ +  VN+LY P +  L+  S
Sbjct:   27 QLGTAMRDPHQQRRIILVIVCVA---LLLDNMLYMVIVPIIPDYLADLENEQLEHVHVVMHPNTSGNSTSQDKSNKNNLDLQIGVLFASKAILQLLVNPLSGTFIDRVGYDIPLLIGLTVMFISTCIFAFGENYATLFAARSLQGLGSAFADTSGIAMIADKYTEEAERSTALGIALAFISFGSLVAPPFGGVLYEFAGKRVPFLVL----------ASICLADGVLVLTV-----IKPFSNRTRE----------------------NMPVGTPIYKLMVDPYIAVVAGALTVANIPLAFLEPTIANWMETTMHSTQWEMGLTWLPAFFPHVLGVYITVKLAAKNPHLQWFYGALGMVIIGASSCTVPACKTFGQLIAPLCGICFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYAMGPIVAGQIVHTLGFVQLNLGMGLVNVLYAPALLLLRTVS 453

[Close]

BLAST of slc18a-5 vs. Ensembl Medaka
Match: slc18a3a (solute carrier family 18 member 3a [Source:NCBI gene;Acc:559347])

HSP 1 Score: 85.1149 bits (209), Expect = 2.914e-17
Identity = 99/459 (21.57%), Postives = 185/459 (40.31%), Query Frame = 1

Query:  106 NRRLEFILIIYCVGSGKFCLEFITSMV-TPIFPSVIFKWQNLS------------SFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYI-RFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRR-HYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFS 1437
             R+   IL+I CV      L+ +  MV  PI P  +   Q  +            S NSS   +    FD  Q+ +L+ +K I Q++V+   G  +DR+G    L IG+ +  ++ + +     Y  L L R  +G+ S     S  A IA ++  +  R K  G     +     V P YGG +Y++  K + FL++            I L++  L + V +     +  N                           M  G+ I + ++DPY  +   +  +  +    L  T+  +++     TE++ G+ W      ++LG  L   L  K  + +  Y  + ++F+ + +S  V A   +     P+C +     + D    P L  + + +H   YG +  +      +  ++   +   ++  +G  +LN+ +   N+LY P +  LK+ S
Sbjct:   39 ERQKRIILVIVCVA---LLLDNMLYMVIVPIIPDYLEGLQKAADNAQHAIVRHSNSTNSSTPKAPTGNFDL-QIGVLFASKAIVQLLVNPISGTFIDRVGYDIPLFIGLNVMFLSTLTFAFAENYATLFLARSIQGLGSAFADTSGIALIADRYTEETERSKALGIALAFISFGSLVAPPYGGVLYEFAGKRVPFLIL----------ACICLIDGVLCLTVLKPFSNQERGN---------------------------MPVGTPIYKLMIDPYIAVVAGALIICNIPLAFLEPTIANWMEDTMQATEWEIGMTWFPAFFPHVLGVYLTVKLAAKHPHLQWFYGAMGMVFIGA-SSCTVPACKNFGQLMIPLCGVCFGIALVDTALLPTLGFLVDVRHVSVYGSVYAIADISYCVAYALGPVVAGQIVHNLGFVQLNLGMGLANVLYAPALLLLKNVS 455

[Close]

BLAST of slc18a-5 vs. Ensembl Medaka
Match: slc18a2 (solute carrier family 18 member A2 [Source:NCBI gene;Acc:101158793])

HSP 1 Score: 58.5362 bits (140), Expect = 7.442e-9
Identity = 41/168 (24.40%), Postives = 77/168 (45.83%), Query Frame = 1

Query:  166 EFITSMVTPIFPS-VIFKWQNLSSFNSSDNVSGFDKF--DYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLI 660
             F T    P+ P+ V+ K Q     NSSD      +   +  ++ +L+ +K   Q++ +  IG + +RIG    +  G  +  ++ +++   S Y +L L R  +G+ S+    +    +A  +   + RG   G     + L   VGP +G  +Y +  KT  FL++
Sbjct:   94 NFTTRPADPVPPTLVVTKLQQ----NSSDCPQSSSRLLNENVKVGMLFASKATVQLVTNPFIGPLTNRIGYQLPIFAGFCIMFLSTIMFAFSSSYTLLFLARSLQGVGSSCSSVAGMGMLASVYTDDEERGHAIGIALGGLALGVLVGPPFGSVMYDFVGKTAPFLIL 257

[Close]

BLAST of slc18a-5 vs. Ensembl Medaka
Match: SLC18A1 (solute carrier family 18 member A1 [Source:NCBI gene;Acc:101172172])

HSP 1 Score: 55.4546 bits (132), Expect = 8.701e-8
Identity = 62/297 (20.88%), Postives = 120/297 (40.40%), Query Frame = 1

Query:  187 TPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFH-LIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKL 1074
             P  P +I +  N S     D+V  F + +   + +L+ +K + Q++V+  +G + +R+G    +  G ++  V+ +++     Y +L   R  +GI S+    +    +A  + + + RG   G     + +   +G  +G  +Y +  K   FL++ +   F   + L IL  +K     V+   L+T                                        L DPY LI+  S     M   IL  TLP ++ +     ++Q G+ +   ++ YL+G  L  +L  K+
Sbjct:   58 NPTPPQLINETANSSCLQ--DSV--FLEEENVHVGLLFASKALIQLLVNPFVGPLTNRVGYHIPMFAGFIIMFVSTIMFAFSGTYALLFFARSLQGIGSSFSSVAGLGMLASVYTNDEERGIAMGIALGGLAMGVLIGAPFGSVMYDFVGKRAPFLILALLAVFDGALQLCILQPSKICPGSVEGTPLLT---------------------------------------LLKDPYILISAGSLCFANMGVAILEPTLPIWMMQTMCSPKWQLGVAFLPASISYLIGTNLFGVLANKM 311

[Close]

BLAST of slc18a-5 vs. Planmine SMEST
Match: SMESG000024277.1 (SMESG000024277.1)

HSP 1 Score: 801.201 bits (2068), Expect = 0.000e+0
Identity = 438/446 (98.21%), Postives = 443/446 (99.33%), Query Frame = 1

Query:  103 MNRRLEFILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 1440
            MNRRLEFILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLSSFNSSDNVSGFD+FDYS+LSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQ NRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDN NHMETL+NSNKNSSSNIANIKENIKSEVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLT++GYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMLTGTSITSSIWSSLGPILL KIGLFKLNIIIYCVNLLYIPLIFFLKDFSV
Sbjct:    1 MNRRLEFILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLSSFNSSDNVSGFDQFDYSRLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQGNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNPNHMETLINSNKNSSSNIANIKENIKSEVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTSIGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMLTGTSITSSIWSSLGPILLNKIGLFKLNIIIYCVNLLYIPLIFFLKDFSV 446

[Close]

BLAST of slc18a-5 vs. Planmine SMEST
Match: SMESG000024278.1 (SMESG000024278.1)

HSP 1 Score: 290.426 bits (742), Expect = 1.702e-92
Identity = 175/476 (36.76%), Postives = 273/476 (57.35%), Query Frame = 1

Query:  124 ILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLS----SFNSSDNVSGFDK-FDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLV----NKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIR------------------------------FLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDF 1434
            +LII+ +   K+ + FIT MV PIFP++I K  N S    + N S  +S  +  F+Y QLSIL+ TKNICQ+++S  +G+   R+G L  L  G+ LQ V+++ YG G+ YF+LI+GRIFE ++S  I C+VS+++AY++      G  +G   L + + G+ GP+YGG+V+QY+ K + FL +L   T   I ++ L++    NK   I+  +  L  + +  +E   ++    S        +    V+   S+                                FL DPYF+I + ++PV++ + ++ YATLP ++K  FG +E QQG+IW L  VGY +GF+LGN LN K    RH VL+V ++V++  ++ +  MP WW  A P+CLI  Q LVF++   P+L+ I  K+H+ ++G MAG+++   ++TSS  S LGPIL  KIG   LNII+  + L+Y PL+  LK F
Sbjct:   10 LLIIFSISLAKYSVGFITGMVIPIFPTLIDKHFNESLPVPAANFSSEISVLNSSFNYQQLSILFATKNICQILLSPWMGYFCGRLGSLNILFSGVGLQTVSILFYGFGNKYFLLIIGRIFEALASGAINCAVSSFVAYRYTDHKKLGLVYGIGGLGLCIGGASGPAYGGWVFQYHGKLMVFLTVLSMTTVEAILILSLMIANKSNKSHHIETIKNPLCAEINEIVENKFDNEIIISMPNNISISSEGVNVLLDNSFKEPKFGSLLNENGNENNHLSVEKSKPEHNIFYFLSDPYFMICLGAFPVMYFSLFVYYATLPHFMKVTFGASESQQGVIWLLNLVGYFIGFLLGNFLNAKFAKSRHIVLMVTVYVHAIGALCISLMPSWWSIAIPLCLIVNQHLVFEIIIAPLLTSIVAKRHESKFGLMAGIIMMAIALTSSCGSFLGPILFSKIGFLYLNIIVAVMGLVYGPLLLMLKQF 485

[Close]

BLAST of slc18a-5 vs. Planmine SMEST
Match: SMESG000069017.1 (SMESG000069017.1)

HSP 1 Score: 93.2041 bits (230), Expect = 6.351e-20
Identity = 114/465 (24.52%), Postives = 213/465 (45.81%), Query Frame = 1

Query:  112 RLEFILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQ-----------LSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVL-YGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVT------DNSNHMETLV-----XXXXXXXXXXXXXXXXXXXXVMNKGS--------YIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPL 1413
            R +++L+I  VG   F +    S +  I P    K+ +  +F   +N S     + S            +S+++ +KN+  + ++  IG I+DR+ +   L+   +L GV+V+L Y   +   + I+GRI +   ++ I  +V + I+  F     R K++G+V+   +++ S+GP YG  V + + K+  FLL LIPI + +  L   L+++R+    K +K V       +N N  +T V      S     S  +   E IK ++ NK S          + L DP  L  +    V+ +  + L  TLP ++  +   +E QQG++WS   +GY+LG  L  I++      R+   V    +     +++     W     P+  ++    V +    P+ + +++  ++  YG M+ L     ++ S I S     + +K G   L I +  +NL + P+
Sbjct:   97 RSDYLLVIIVVGLNFFMMVIEESSLYTILP----KYLSNRTFGEINNYSRIYASNLSMKCVSKDPPYVIISMIFLSKNLATIFINPIIGMILDRMNNFIILIFAQIL-GVSVLLVYAFSNSILMYIIGRIIDAFVTSVIFLAVYSIISQMFLETRIRSKYYGFVNTLFFVSHSLGPVYGASVDEKFGKSAVFLL-LIPI-WSISLLFTYLLHRRIKTINKNKKGVPRFLEIMENHNWNDTRVDSPNNESKNLILSESSEKNETIKVKIENKQSGNHRTLFTIFKMLKDPKVLACLVQIFVVNLCMFSLPPTLPSWMAFKLCSSELQQGIVWSFGFLGYILGVSLVIIIDAYAPRFRNLAPVAGQIIIGIQLIMIPFTRDWRFLFLPIIGMYISVGVVEQIILPLTTYLSDSLYNSNYGTMSSLTSQSLNLCSVISSLCSGPIAEKYGFTTLAIALGIINLSFSPI 554

[Close]

BLAST of slc18a-5 vs. Planmine SMEST
Match: SMESG000070401.1 (SMESG000070401.1)

HSP 1 Score: 84.3445 bits (207), Expect = 3.230e-17
Identity = 79/403 (19.60%), Postives = 181/403 (44.91%), Query Frame = 1

Query:  283 QLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYY--SKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMET------------LVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFA-----FPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDF 1434
            ++S + G++++  +I +   G +++  G ++   IG+  +    ++ G  + Y +LI+G+  EG  S+ +  +    I+ KF   + +    G  S+ + L   V P   G +Y+ +     +A  L ++   F  I LI +++NK+ +     +  + + +N +E             L+    +  S    ++    + V       + L+DPY  I +       + +Y L  TL  +L + FG+ E  QGL+W  + +  +  ++LG +L   + ++ +  +++   ++  +++ +  +P WW+       F + L   +FL+      P++  I++ +H+  +G +A ++     I ++        ++ + G   LN+ +     +Y     FLK F
Sbjct:   32 RISFIMGSRSLVHLIFTPIWGILINIFGPIQFGYIGLTTEIFGCLMLGFANTYIMLIIGKCIEGFGSSLVTVAALTIISLKFHDYEEKSCIMGLTSISIVLGNYVSPFVAGILYENFKLDGQMAVYLSMVFCKFINI-LIYVVINKKSVEVEDFKDSIINRNNSIEPDRRSSSLKGTYHLLEKIGSGESLGMMMESEFITHVTETTPIYKLLIDPYIAICILGIIACHLPHYSLLTTLSIWLHERFGVNETIQGLVWVPSFIFNIFTYLLGLVLVKYVPHQGYIFVIISFIISGASNIALPFLPSWWLVMIVLSNFALNLTLVKFLLL-----PLVVMISDLRHNSVHGSVAAIINESMHIGAAFSFFAAGSIVNRFGFLVLNLSVATTAFIYCIFGLFLKPF 428

[Close]

BLAST of slc18a-5 vs. Planmine SMEST
Match: SMESG000051356.1 (SMESG000051356.1)

HSP 1 Score: 75.485 bits (184), Expect = 3.174e-14
Identity = 85/422 (20.14%), Postives = 172/422 (40.76%), Query Frame = 1

Query:  181 MVTPIFPSVIFKWQNLSSFNSSDNVSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQGVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGKWFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIILLVNKRLIIKVKERKLVTDNSNHMETLVXXXXXXXXXXXXXXXXXXXXVMNKGSYIRFL-LDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGI-TEFQQGLIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMPYWWMFAF---PVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMXXXXXXXXXXXXXXXPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKD 1431
            ++ PI P  +   +N    N+        +   +Q+ +L+  K I Q++++   G ++DRIG    ++IG+++  V+   +  G    V+ L R  +G+ S     S  A IA +F  + +R    G     +     V P +G  +YQY  K   F  +          L++++   RL     ER+ +    N                           + KG+ I+ L +DPY  I   +  +  ++   L  T+  ++     + +E   GLIW      ++ G  +   L  K    +  +  + L +   + + +   P+   F +   P+ L+     + D    P L  + + +H   YG +  +     S+  +I   +   ++  IG   LNII++ V++ Y P+++ +++
Sbjct:  133 VIVPIVPHYMDYMKNKGQSNNESMSMMHTEEGNTQMGLLFACKAIVQLLINPLSGTVIDRIGYDIPMMIGLIIIFVSTSAFAFGQTLEVMFLARGLQGVGSAFADTSGLAMIADRFTEESSRTTALGIALAFISFGSLVAPPFGAVLYQYCGKEFPFFCLAFIALLDGFLLMMIMKPVRL-----ERREMKAEGN---------------------------LPKGTPIQKLFMDPYIAICAGTLAIANVSLAFLEPTITSWMLSWRPVPSESAIGLIWLPAFFPHVAGVFVTVKLAAKYPQYQWLMAGIGLALEGISCIFI---PFCSNFGYLMIPISLLCFGIALVDTAILPTLGYLVDTRHVSVYGSVYAIADISYSLAYAIGPIVAGSIVSTIGFTSLNIIVFVVSIAYCPVLYLMRN 519

The following BLAST results are available for this feature:

BLAST of slc18a-5 vs. Ensembl Human
BLAST of slc18a-5 vs. Ensembl Celegans
BLAST of slc18a-5 vs. Ensembl Fly
BLAST of slc18a-5 vs. Ensembl Zebrafish
BLAST of slc18a-5 vs. Ensembl Xenopus
BLAST of slc18a-5 vs. Ensembl Mouse
BLAST of slc18a-5 vs. UniProt/SwissProt
BLAST of slc18a-5 vs. TrEMBL
BLAST of slc18a-5 vs. Ensembl Cavefish
BLAST of slc18a-5 vs. Ensembl Sea Lamprey
BLAST of slc18a-5 vs. Ensembl Yeast
BLAST of slc18a-5 vs. Ensembl Nematostella
BLAST of slc18a-5 vs. Ensembl Medaka
BLAST of slc18a-5 vs. Planmine SMEST

BLAST of slc18a-5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC18A3	8.256e-12	22.46	solute carrier family 18 member A3 [Source:HGNC Sy...	[more]
SLC18A1	1.426e-8	21.63	solute carrier family 18 member A1 [Source:HGNC Sy...	[more]
SLC18A1	1.426e-8	21.63	solute carrier family 18 member A1 [Source:HGNC Sy...	[more]
SLC18A2	5.682e-8	22.26	solute carrier family 18 member A2 [Source:HGNC Sy...	[more]
SLC18A1	5.620e-6	21.90	solute carrier family 18 member A1 [Source:HGNC Sy...	[more]

BLAST of slc18a-5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
cat-1	1.882e-15	22.65	pep chromosome:WBcel235:X:5705719:5710585:-1 gene:...	[more]
cat-1	2.457e-15	22.65	pep chromosome:WBcel235:X:5705719:5710625:-1 gene:...	[more]
unc-17	3.367e-8	25.40	Vesicular acetylcholine transporter unc-17 [Sourc...	[more]

BLAST of slc18a-5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
VAChT	9.167e-16	21.01	gene:FBgn0270928 transcript:FBtr0083671	[more]
Vmat	9.346e-12	22.26	gene:FBgn0260964 transcript:FBtr0310062	[more]
Vmat	9.346e-12	22.26	gene:FBgn0260964 transcript:FBtr0091491	[more]
Vmat	9.346e-12	22.26	gene:FBgn0260964 transcript:FBtr0091493	[more]
Vmat	1.016e-11	22.26	gene:FBgn0260964 transcript:FBtr0091492	[more]

BLAST of slc18a-5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc18a3a	3.153e-19	20.47	solute carrier family 18 member 3a [Source:NCBI ge...	[more]
SLC18A1	3.171e-12	20.96	solute carrier family 18 member A1 [Source:NCBI ge...	[more]
slc18a2	2.575e-11	22.11	solute carrier family 18 member 2 [Source:ZFIN;Acc...	[more]
slc18a2	6.654e-11	21.05	solute carrier family 18 member 2 [Source:ZFIN;Acc...	[more]
SLC18A1	6.783e-11	20.71	solute carrier family 18 member A1 [Source:NCBI ge...	[more]

BLAST of slc18a-5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc18a3	1.473e-17	21.72	solute carrier family 18 (vesicular acetylcholine ...	[more]
ddx42	8.267e-9	20.47	DEAD-box helicase 42 [Source:Xenbase;Acc:XB-GENE-9...	[more]
ddx42	1.229e-8	19.46	DEAD-box helicase 42 [Source:Xenbase;Acc:XB-GENE-9...	[more]
ddx42	7.268e-7	25.47	DEAD-box helicase 42 [Source:Xenbase;Acc:XB-GENE-9...	[more]
ddx42	7.680e-7	25.47	DEAD-box helicase 42 [Source:Xenbase;Acc:XB-GENE-9...	[more]

BLAST of slc18a-5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Slc18a3	3.245e-12	21.86	solute carrier family 18 (vesicular monoamine), me...	[more]
Slc18a2	5.045e-8	21.89	solute carrier family 18 (vesicular monoamine), me...	[more]

BLAST of slc18a-5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q08C75\|VACHA_DANRE	2.380e-18	20.47	Probable vesicular acetylcholine transporter-A OS=...	[more]
sp\|P59845\|VACHB_DANRE	1.872e-17	20.38	Probable vesicular acetylcholine transporter-B OS=...	[more]
sp\|P81721\|VACHT_TETCF	1.870e-16	21.09	Vesicular acetylcholine transporter OS=Tetronarce ...	[more]
sp\|O17444\|VACHT_DROME	9.189e-15	21.01	Vesicular acetylcholine transporter OS=Drosophila ...	[more]
sp\|Q91498\|VACHT_TORMA	1.114e-14	21.61	Vesicular acetylcholine transporter OS=Torpedo mar...	[more]

BLAST of slc18a-5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0H3YF28	0.000e+0	100.00	Slc18a-5 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
A0A0H3YK86	6.121e-89	36.76	Slc18a-3 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
A4KWG5	1.833e-22	24.79	Vesicular acetylcholine transporter OS=Branchiosto...	[more]
T1EMB8	5.278e-20	24.30	MFS domain-containing protein OS=Helobdella robust...	[more]
A0A4D9E5M6	2.022e-18	20.85	5'-AMP-activated protein kinase subunit beta-1 OS=...	[more]

BLAST of slc18a-5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc18a3b	1.773e-13	20.40	solute carrier family 18 member 3b [Source:NCBI ge...	[more]
slc18a2	2.782e-12	22.00	synaptic vesicular amine transporter [Source:NCBI ...	[more]
SLC18A1	1.011e-10	20.66	solute carrier family 18 member A1 [Source:NCBI ge...	[more]
slc18a3a	4.135e-9	19.23	solute carrier family 18 member A3 [Source:NCBI ge...	[more]
SLC18A1	1.170e-7	21.37	solute carrier family 18 member A1 [Source:NCBI ge...	[more]

BLAST of slc18a-5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
slc18a3a	9.249e-20	20.82	solute carrier family 18 member 3a [Source:NCBI ge...	[more]
slc18a2	6.719e-7	21.43	solute carrier family 18 member 2 [Source:ZFIN;Acc...	[more]

BLAST of slc18a-5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of slc18a-5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of slc18a-5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
slc18a3b	7.565e-18	21.20	probable vesicular acetylcholine transporter-B [So...	[more]
slc18a3a	2.914e-17	21.57	solute carrier family 18 member 3a [Source:NCBI ge...	[more]
slc18a2	7.442e-9	24.40	solute carrier family 18 member A2 [Source:NCBI ge...	[more]
SLC18A1	8.701e-8	20.88	solute carrier family 18 member A1 [Source:NCBI ge...	[more]

BLAST of slc18a-5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000024277.1	0.000e+0	98.21	SMESG000024277.1	[more]
SMESG000024278.1	1.702e-92	36.76	SMESG000024278.1	[more]
SMESG000069017.1	6.351e-20	24.52	SMESG000069017.1	[more]
SMESG000070401.1	3.230e-17	19.60	SMESG000070401.1	[more]
SMESG000051356.1	3.174e-14	20.14	SMESG000051356.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30006235
GenBank	AKN21540.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30006235 ID=SMED30006235|Name=slc18a-5|organism=Schmidtea mediterranea sexual|type=transcript|length=1500bp
CAGTTACGTTTGCATAGGCTACTTTCTGTTCATTTGTAATCAATAATTTC
TACTCGAGATGTAACTGAAATTTTATTACAATTCTTTTCAAACTACTCAC
AAATGAATCGCAGATTAGAATTCATATTAATCATATATTGTGTTGGAAGT
GGCAAATTTTGCTTGGAATTTATAACATCAATGGTAACTCCAATATTTCC
AAGCGTGATTTTCAAATGGCAAAATCTGTCATCATTCAACAGTTCAGACA
ATGTTTCTGGATTTGACAAATTCGATTATAGTCAACTTTCAATTCTATAC
GGAACGAAAAACATTTGCCAAGTGATAGTCAGTATGACAATCGGTTTCAT
TGTCGATCGAATTGGAGATCTTGAAACTTTGCTCATTGGAATGATGCTTC
AAGGTGTTGCTGTTGTTTTGTATGGGGTTGGATCGGTTTATTTTGTTTTG
ATTCTGGGTCGAATATTTGAAGGAATAAGCTCCACCACAATCCAATGCTC
AGTTTCCGCCTATATAGCTTATAAGTTCAAATCCCAAGACAATCGAGGAA
AATGGTTTGGTTATGTCTCACTATGTATGTATTTGGCAGGATCGGTTGGG
CCAAGTTATGGTGGATTTGTCTATCAATATTATAGCAAAACGTTAGCATT
TCTTTTAATTTTAATTCCTATTACTTTTCACTTGATACCTTTGATCATAT
TGTTGGTTAATAAAAGGCTAATAATCAAAGTAAAAGAACGCAAATTAGTT
ACAGATAACTCAAATCACATGGAAACTTTGGTTAACTCAAATAAGAATTC
ATCGAGCAACATTGCAAATATTAAAGAAAACATTAAATCTGAAGTAATGA
ACAAAGGTAGCTATATCCGATTTTTACTTGATCCTTATTTTCTGATTGCT
ATGAATAGTTACCCCGTTCTTTTTATGACCTATTACATACTTTATGCTAC
TTTGCCAAGGTATTTGAAGAAAGAGTTTGGAATTACAGAGTTTCAGCAAG
GATTGATTTGGTCTTTGACAGCAGTAGGGTATTTGTTAGGATTTATTCTG
GGAAACATTTTGAATACAAAACTGCAAAATCGTCGACATTATGTTTTGGT
TGTGATTTTATTCGTCAATTCGTTTACGAGCGTAATCGTTTGTGCGATGC
CCTATTGGTGGATGTTTGCCTTTCCGGTCTGTCTTATTTTCACACAATTT
TTAGTTTTCGATATGTTTTGTCCGCCGATTTTGTCGAAAATAACAGAAAA
GAAACATGATAAACAATATGGAAAAATGGCAGGTTTGATGTTAACAGGAA
CCTCAATCACTTCATCAATATGGTCATCATTAGGTCCGATTTTATTAAAG
AAAATAGGGTTGTTTAAGTTGAATATCATAATATATTGTGTGAATCTTTT
ATATATTCCTTTGATATTCTTTTTGAAAGATTTTTCTGTAAAATAGAATT
TTATTTTTAGAAAGATTATTAGGATAGATTTCGAAAATATTTTATTTTTG

protein sequence of SMED30006235-orf-1

>SMED30006235-orf-1 ID=SMED30006235-orf-1|Name=SMED30006235-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=116bp
KNKIFSKSILIIFLKIKFYFTEKSFKKNIKGIYKRFTQYIMIFNLNNPIF
FNKIGPNDDHIDEVIEVPVNIKPAIFPYCLSCFFSVIFDKIGGQNISKTK
NCVKIRQTGKANIHQ*

protein sequence of SMED30006235-orf-2

>SMED30006235-orf-2 ID=SMED30006235-orf-2|Name=SMED30006235-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=448bp
MNRRLEFILIIYCVGSGKFCLEFITSMVTPIFPSVIFKWQNLSSFNSSDN
VSGFDKFDYSQLSILYGTKNICQVIVSMTIGFIVDRIGDLETLLIGMMLQ
GVAVVLYGVGSVYFVLILGRIFEGISSTTIQCSVSAYIAYKFKSQDNRGK
WFGYVSLCMYLAGSVGPSYGGFVYQYYSKTLAFLLILIPITFHLIPLIIL
LVNKRLIIKVKERKLVTDNSNHMETLVNSNKNSSSNIANIKENIKSEVMN
KGSYIRFLLDPYFLIAMNSYPVLFMTYYILYATLPRYLKKEFGITEFQQG
LIWSLTAVGYLLGFILGNILNTKLQNRRHYVLVVILFVNSFTSVIVCAMP
YWWMFAFPVCLIFTQFLVFDMFCPPILSKITEKKHDKQYGKMAGLMLTGT
SITSSIWSSLGPILLKKIGLFKLNIIIYCVNLLYIPLIFFLKDFSVK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0022857	transmembrane transporter activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR036259	MFS_trans_sf
IPR011701	MFS
IPR020846	MFS_dom

Vocabulary: **biological process**
Term	Definition
GO:0055085	transmembrane transport

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0016020	membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR011701	Major facilitator superfamily	PFAM	PF07690	MFS_1	coord: 17..406 e-value: 4.2E-30 score: 104.9
None	No IPR available	PANTHER	PTHR23506	FAMILY NOT NAMED	coord: 8..442
None	No IPR available	CDD	cd17325	MFS_MdtG_SLC18_like	coord: 19..442 e-value: 1.73537E-23 score: 99.1876
None	No IPR available	TMHMM	TMhelix		coord: 258..280
None	No IPR available	TMHMM	TMhelix		coord: 419..441
None	No IPR available	TMHMM	TMhelix		coord: 351..373
None	No IPR available	TMHMM	TMhelix		coord: 329..346
None	No IPR available	TMHMM	TMhelix		coord: 393..415
None	No IPR available	TMHMM	TMhelix		coord: 7..29
None	No IPR available	TMHMM	TMhelix		coord: 151..170
None	No IPR available	TMHMM	TMhelix		coord: 180..202
None	No IPR available	TMHMM	TMhelix		coord: 300..322
None	No IPR available	TMHMM	TMhelix		coord: 97..119
IPR020846	Major facilitator superfamily domain	PROSITE	PS50850	MFS	coord: 10..446 score: 12.845
IPR036259	MFS transporter superfamily	SUPERFAMILY	SSF103473	MFS general substrate transporter	coord: 11..442

Main menu

slc18a-5

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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