Exosome complex component RRP40

Overview
NameExosome complex component RRP40
Smed IDSMED30006169
Length (bp)1085
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Exosome complex component RRP40 (SMED30006169) t-SNE clustered cells

Violin plots show distribution of expression levels for Exosome complex component RRP40 (SMED30006169) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Exosome complex component RRP40 (SMED30006169) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Exosome complex component RRP40 (SMED30006169) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006169

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30006169SMESG000002729.1 SmedASXL_008194SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30006169SMESG000002729.1 SmedASXL_008194SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Human
Match: EXOSC3 (exosome component 3 [Source:HGNC Symbol;Acc:HGNC:17944])

HSP 1 Score: 115.161 bits (287), Expect = 3.184e-29
Identity = 73/201 (36.32%), Postives = 122/201 (60.70%), Query Frame = 2 
Query:  212 VLISHSGVLKFSKPNR------IWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFC---KKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTI 787
            +L++  G L+  +P         W++S  K Y+PVKGD +IG +  KSGD ++V+ GG   A L YL+F+ ATK NRPNV++GD+IY +F++A + +EPE+ C++  G++ GMG++  +   +++V L   RKLL     P C   +++G  + P EI+ G NG IW+ AK+ ++ + L N +    H+ +   KQ+   +
Sbjct:   78 LLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQD-GLLFKVTLGLIRKLLA----PDCEIIQEVGK-LYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRL 272
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Human
Match: EXOSC3 (exosome component 3 [Source:HGNC Symbol;Acc:HGNC:17944])

HSP 1 Score: 47.3654 bits (111), Expect = 6.630e-6
Identity = 35/81 (43.21%), Postives = 51/81 (62.96%), Query Frame = 2 
Query:  212 VLISHSGVLKFSKPNR------IWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVK 436
            +L++  G L+  +P         W++S  K Y+PVKGD +IG +  KSGD ++V+ GG   A L YL+F+ ATK NRPNV+
Sbjct:   78 LLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQ 158
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Human
Match: EXOSC3 (exosome component 3 [Source:HGNC Symbol;Acc:HGNC:17944])

HSP 1 Score: 47.3654 bits (111), Expect = 6.630e-6
Identity = 35/81 (43.21%), Postives = 51/81 (62.96%), Query Frame = 2 
Query:  212 VLISHSGVLKFSKPNR------IWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVK 436
            +L++  G L+  +P         W++S  K Y+PVKGD +IG +  KSGD ++V+ GG   A L YL+F+ ATK NRPNV+
Sbjct:   78 LLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQ 158
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Celegans
Match: exos-3 (EXOSome (Multiexonuclease complex) component [Source:UniProtKB/TrEMBL;Acc:Q93830])

HSP 1 Score: 92.8189 bits (229), Expect = 9.395e-22
Identity = 65/206 (31.55%), Postives = 111/206 (53.88%), Query Frame = 2 
Query:   92 YMPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGT--GILPHEIIIGSNGWIWLSAKSS 703
            Y+PG ++ E  +     D  ++G+G+ V    +++  +     +  G        ++W+   SK YIP +GD++I  +  K+GD+++++ G    A + + NF+ ATK NRPN+K GD+IY          E E+TCV++  ++ GMG +  N   +++V L   R+L+N    P CK + T       EI +G NG IW+SA +S
Sbjct:    4 YLPGDVINEPSS----SDSSIIGYGISV-RGQTRIATQPGAFHNDDG--------KVWLNVHSKRYIPQEGDRVIAIVTSKTGDFFRLDIGTAEYAMINFTNFEGATKRNRPNLKTGDIIYATVFDTTPRTEAELTCVDDEKRARGMGQL--NGGFMFKVSLNHCRRLIN----PSCKILQTVGKFFKFEITVGMNGRIWISASTS 190
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Fly
Match: Rrp40 (gene:FBgn0260648 transcript:FBtr0077883)

HSP 1 Score: 114.775 bits (286), Expect = 1.063e-29
Identity = 79/227 (34.80%), Postives = 125/227 (55.07%), Query Frame = 2 
Query:   95 MPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQL 775
            MPG  +   + L +   +++LG GL  +++         V+ S +G L+  +P   W+++  + YIP +GD I+G +  K+GD Y+V+ G    A + YL F+ A+K NRP++  GD+IY   L A   IEPE+ CVN +GKS  +G++   +   ++  L   R LL  E+ P    + T  LP+EI +G NG IWL A S +E V L N+IS       + I ++
Sbjct:    9 MPGERIAAIEELAK-SKRVILGPGLRRLDD--------TVVASKAGPLRHKEPGTFWVDNYQRRYIPARGDLILGIVRAKAGDLYRVDIGATDTASISYLAFEAASKKNRPDLIPGDLIYARVLNASADIEPELVCVNSVGKSGKLGVL--TDGFFFKCSLNLGRMLLR-ENCPVLAAL-TRELPYEIAVGVNGRIWLKAHSLKETVALANAISALEQSGCAEIDKI 222
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Fly
Match: Rrp40 (gene:FBgn0260648 transcript:FBtr0345430)

HSP 1 Score: 114.775 bits (286), Expect = 1.063e-29
Identity = 79/227 (34.80%), Postives = 125/227 (55.07%), Query Frame = 2 
Query:   95 MPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQL 775
            MPG  +   + L +   +++LG GL  +++         V+ S +G L+  +P   W+++  + YIP +GD I+G +  K+GD Y+V+ G    A + YL F+ A+K NRP++  GD+IY   L A   IEPE+ CVN +GKS  +G++   +   ++  L   R LL  E+ P    + T  LP+EI +G NG IWL A S +E V L N+IS       + I ++
Sbjct:    9 MPGERIAAIEELAK-SKRVILGPGLRRLDD--------TVVASKAGPLRHKEPGTFWVDNYQRRYIPARGDLILGIVRAKAGDLYRVDIGATDTASISYLAFEAASKKNRPDLIPGDLIYARVLNASADIEPELVCVNSVGKSGKLGVL--TDGFFFKCSLNLGRMLLR-ENCPVLAAL-TRELPYEIAVGVNGRIWLKAHSLKETVALANAISALEQSGCAEIDKI 222
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Zebrafish
Match: exosc3 (exosome component 3 [Source:ZFIN;Acc:ZDB-GENE-050706-140])

HSP 1 Score: 113.235 bits (282), Expect = 6.200e-29
Identity = 67/218 (30.73%), Postives = 122/218 (55.96%), Query Frame = 2 
Query:  143 DKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRG 796
            D+L+ G GL          +   + +  +GVLK  +PN  W+    + Y+P KG+ +IG +  KSGD ++V+ GG   A L YL F+ ATK NRPNV++GD+++ +F +A + +EPE+ C++  G++ GMG+    +  +++V L   R+LL  +S          + P E+++G NG +W+ A++ +  + L N +    +++ +    L + +  G
Sbjct:   39 DRLICGPGLR--------RSGAEIRVCRAGVLKHKQPNMYWVNCQQRRYVPAKGESVIGIVTAKSGDVFKVDVGGSEQASLSYLAFEGATKRNRPNVQVGDLVFGQFTIANKDMEPELVCIDSCGRANGMGVFG-GDGLLFKVSLGLVRRLLAPQSDLVSDL--EKMFPCEMVVGMNGRVWVKARTVQHTLILSNLLEACENMSTAQRHTLFRRVADG 245
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Zebrafish
Match: exosc3 (exosome component 3 [Source:ZFIN;Acc:ZDB-GENE-050706-140])

HSP 1 Score: 112.849 bits (281), Expect = 1.049e-28
Identity = 67/218 (30.73%), Postives = 122/218 (55.96%), Query Frame = 2 
Query:  143 DKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRG 796
            D+L+ G GL          +   + +  +GVLK  +PN  W+    + Y+P KG+ +IG +  KSGD ++V+ GG   A L YL F+ ATK NRPNV++GD+++ +F +A + +EPE+ C++  G++ GMG+    +  +++V L   R+LL  +S          + P E+++G NG +W+ A++ +  + L N +  + +++ +    L   +  G
Sbjct:   39 DRLICGPGLR--------RSGAEIRVCRAGVLKHKQPNMYWVNCQQRRYVPAKGESVIGIVTAKSGDVFKVDVGGSEQASLSYLAFEGATKRNRPNVQVGDLVFGQFTIANKDMEPELVCIDSCGRANGMGVFG-GDGLLFKVSLGLVRRLLAPQSDLVSDL--EKMFPCEMVVGMNGRVWVKARTVQHTLILSNLLEASENMSTAQRHTLFSRVADG 245
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Xenopus
Match: EXOSC3 (exosome component 3 [Source:NCBI gene;Acc:100491278])

HSP 1 Score: 112.079 bits (279), Expect = 2.319e-28
Identity = 69/188 (36.70%), Postives = 115/188 (61.17%), Query Frame = 2 
Query:  212 VLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQL 775
            +L++  G+L+   P   W++S  K Y+PVKGD +IG +  KSGD ++V+ GG   A L YL F+ ATK NRPNVK+GD++Y +F++A + +EPE+ C++  GK+ G G++   +  + +V L   RKLL I      +++   I P E++IG NG IW+ AK+ ++ + + N +    ++     K +
Sbjct:   57 LLVNKCGLLRHRDPAIYWVDSQQKRYVPVKGDHVIGIVTTKSGDIFKVDVGGSEQASLSYLAFEGATKKNRPNVKVGDLVYGQFIVANKDMEPEMACIDSSGKANGKGVIGQ-DGLMLKVSLGLVRKLL-IPQNDIVQEL-MNIFPMEVVIGMNGRIWVKAKTVQQTLIVANLLEACEYLTAEQRKHV 241
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Mouse
Match: Exosc3 (exosome component 3 [Source:MGI Symbol;Acc:MGI:1913612])

HSP 1 Score: 110.538 bits (275), Expect = 1.134e-27
Identity = 72/200 (36.00%), Postives = 121/200 (60.50%), Query Frame = 2 
Query:  212 VLISHSGVLKFSKPNR-----IWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFC---KKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTI 787
            +L++  G L+  +P+       W++S  K Y+PVKGD +IG ++ KSGD ++V+ GG   A L YL F+ ATK NRPNV++GD+IY + ++A + +EPE+ C++  G++ GMG++  +   +++V L   RKLL     P C   +++G  + P EI+ G NG IW+ AK+ ++ + L N +    H+     KQ+   +
Sbjct:   78 LLVTKCGRLRHKEPSGGGGGVYWVDSQQKRYVPVKGDHVIGIVIAKSGDIFKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQD-GLLFKVTLGLIRKLL----APDCEIVQELGK-LYPLEIVFGMNGRIWVKAKTIQQTLILANVLEACEHMTTEQRKQIFARL 271
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Mouse
Match: Exosc3 (exosome component 3 [Source:MGI Symbol;Acc:MGI:1913612])

HSP 1 Score: 76.2554 bits (186), Expect = 2.680e-16
Identity = 42/110 (38.18%), Postives = 70/110 (63.64%), Query Frame = 2 
Query:  347 YQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFC---KKIGTGILPHEIIIG 667
            ++V+ GG   A L YL F+ ATK NRPNV++GD+IY + ++A + +EPE+ C++  G++ GMG++  +   +++V L   RKLL     P C   +++G  + P EI+ G
Sbjct:   41 FKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQD-GLLFKVTLGLIRKLLA----PDCEIVQELGK-LYPLEIVFG 144
[Close]
BLAST of Exosome complex component RRP40 vs. UniProt/SwissProt
Match: sp|Q9NQT5|EXOS3_HUMAN (Exosome complex component RRP40 OS=Homo sapiens OX=9606 GN=EXOSC3 PE=1 SV=3)

HSP 1 Score: 115.161 bits (287), Expect = 1.529e-28
Identity = 73/201 (36.32%), Postives = 122/201 (60.70%), Query Frame = 2 
Query:  212 VLISHSGVLKFSKPNR------IWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFC---KKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTI 787
            +L++  G L+  +P         W++S  K Y+PVKGD +IG +  KSGD ++V+ GG   A L YL+F+ ATK NRPNV++GD+IY +F++A + +EPE+ C++  G++ GMG++  +   +++V L   RKLL     P C   +++G  + P EI+ G NG IW+ AK+ ++ + L N +    H+ +   KQ+   +
Sbjct:   78 LLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQD-GLLFKVTLGLIRKLLA----PDCEIIQEVGK-LYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRL 272
[Close]
BLAST of Exosome complex component RRP40 vs. UniProt/SwissProt
Match: sp|Q3T0E1|EXOS3_BOVIN (Exosome complex component RRP40 OS=Bos taurus OX=9913 GN=EXOSC3 PE=2 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 4.834e-28
Identity = 73/201 (36.32%), Postives = 120/201 (59.70%), Query Frame = 2 
Query:  212 VLISHSGVLKFSKPNR------IWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFC---KKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTI 787
            +L++  G L+  +P         W++S  K Y+PVKGD +IG +  KSGD ++V+ GG   A L YL F+ ATK NRPNV++GD+IY +F++A + +EPE+ C++  G++ GMG++  +   +++V L   RKLL     P C   +++G  + P EI+ G NG IW+ AK+ ++ + L N +    H+     KQ+   +
Sbjct:   78 LLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQD-GLLFKVTLGLIRKLL----APDCEILQEVGK-LYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTADQRKQIFSRL 272
[Close]
BLAST of Exosome complex component RRP40 vs. UniProt/SwissProt
Match: sp|Q7TQK4|EXOS3_MOUSE (Exosome complex component RRP40 OS=Mus musculus OX=10090 GN=Exosc3 PE=1 SV=3)

HSP 1 Score: 110.538 bits (275), Expect = 7.931e-27
Identity = 72/200 (36.00%), Postives = 121/200 (60.50%), Query Frame = 2 
Query:  212 VLISHSGVLKFSKPNR-----IWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFC---KKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTI 787
            +L++  G L+  +P+       W++S  K Y+PVKGD +IG ++ KSGD ++V+ GG   A L YL F+ ATK NRPNV++GD+IY + ++A + +EPE+ C++  G++ GMG++  +   +++V L   RKLL     P C   +++G  + P EI+ G NG IW+ AK+ ++ + L N +    H+     KQ+   +
Sbjct:   78 LLVTKCGRLRHKEPSGGGGGVYWVDSQQKRYVPVKGDHVIGIVIAKSGDIFKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQD-GLLFKVTLGLIRKLL----APDCEIVQELGK-LYPLEIVFGMNGRIWVKAKTIQQTLILANVLEACEHMTTEQRKQIFARL 271
[Close]
BLAST of Exosome complex component RRP40 vs. UniProt/SwissProt
Match: sp|Q7KWX9|EXOS3_DICDI (Putative exosome complex component rrp40 OS=Dictyostelium discoideum OX=44689 GN=exosc3 PE=3 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 8.687e-23
Identity = 72/231 (31.17%), Postives = 129/231 (55.84%), Query Frame = 2 
Query:   89 FYMPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRI-WIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLI 778
            F +PG ++ +   L     K+ +G GL        L+ K  VL + +GVL++SK +R  WIE+  K Y+P   D +IG I++K  + ++V+ G  C A L   +F+ ATK+N+P + +G++IYC   +A R +EPEV C+++  K+ G G +      +    L  +  LL+ + F   + +G  I P+EI +G NG +W+++ S+   + + N+I  + ++ +  I+  I
Sbjct:    8 FVVPGDVIGKIGDL-----KVRIGPGL--------LQTKDTVLATKAGVLRYSKFHRFYWIENEQKRYVPQVEDMVIGTIIEKHAESFKVDIGSSCSALLSAYSFEGATKSNKPLLNVGNLIYCRVTVANRDMEPEVVCLSQKQKAEGFGQLIGG--YMLNCSLGLSHYLLSEDCF-LLQILGKHI-PYEIAVGVNGRVWINSGSNHNTIVVSNTIYNSQYIQDDQIEPFI 221
[Close]
BLAST of Exosome complex component RRP40 vs. UniProt/SwissProt
Match: sp|O13903|RRP40_SCHPO (Exosome complex component rrp40 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rrp40 PE=3 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 6.486e-18
Identity = 69/238 (28.99%), Postives = 126/238 (52.94%), Query Frame = 2 
Query:   89 FYMPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNE-IGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNN----SHIKQLIKTI 787
            +Y PG  +   D++   +  + LG GL     + K + +  +++S +G L  +  N + I+S +K YIP   D++IG+I+ +  + Y+V+ G    AQL  L F+  T+ +RPN+ +G ++Y    LA R +EPE+ C +   GK+ G G +  N   I  + L   RKL+ +      + +G+ I P EI +G NG +W+++++    V +  +I     +++     + K LIK +
Sbjct:   12 YYFPGERIP--DSIISQDGSIRLGPGLV----FQKKDREEEIVVSKAGRLHQTGKNAMLIDSRTKRYIPATNDQVIGQIISRFAEGYRVDIGSAHIAQLNALAFENVTRKSRPNLNVGSLVYARVSLADRDMEPELECFDATTGKAAGYGEL-KNGYMITGLSLSHCRKLI-LPKNTLLQTLGSYI-PFEIAVGMNGRVWVNSENLSTTVLICTAIRNCEFMSDEEQIKYCKDLIKKL 240
[Close]
BLAST of Exosome complex component RRP40 vs. TrEMBL
Match: K1PH06 (Exosome complex exonuclease RRP40 OS=Crassostrea gigas OX=29159 GN=CGI_10014647 PE=4 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 1.657e-35
Identity = 81/208 (38.94%), Postives = 129/208 (62.02%), Query Frame = 2 
Query:  146 KLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIK 769
            K+VLG G+         +    V++S  GVLKF +PN  W++S  K YIP +GD +IG I  K+GD ++V+ G    A L YL F+ ATK NRP+VK+GD++YC+FL+A + +EPE+ C++  GKS G+G++  +   + QV +   +K+L+ E   F K +G   L +E+ +G NG IW+   +  E + + N+IS++ H+ N  I+
Sbjct:   26 KVVLGPGIR--------QETDLVIVSKPGVLKFKEPNIYWVDSFQKRYIPQRGDSVIGIITTKAGDVFRVDVGASELATLPYLAFESATKRNRPDVKVGDIVYCKFLVANKDMEPELVCIDGSGKSAGLGVIGRDGGMLLQVPINLVQKVLSPECVLF-KTLGKN-LKYEVAVGMNGRIWIKCHTVMETIAVANAISVSQHMTNQDIQ 223
[Close]
BLAST of Exosome complex component RRP40 vs. TrEMBL
Match: A0A2T7NS46 (KH_dom_type_1 domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_17239 PE=4 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 2.146e-34
Identity = 80/214 (37.38%), Postives = 135/214 (63.08%), Query Frame = 2 
Query:  146 KLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTI 787
            K++LG GL       +LE++  + ++ SG+L+F +PN  W++S    Y+PVKG+ +IG I +K GD ++V+ GG   A L +L+F+ ATK NRP+VK+GD++YC  L+A + +EPEV C++  G+S GMG++  N   + +  L   RK+LN +     K +G  I P E  +G NG +W+ A+S++E + + N+I  + ++ N  IK + + +
Sbjct:   39 KIILGPGL-------RLEDE-DICVAKSGILRFREPNVYWVDSHQTRYVPVKGETVIGIITQKVGDTFRVDIGGSEQASLSFLSFEGATKRNRPDVKVGDIVYCRLLVANKDMEPEVVCIDGQGRSSGMGVI-RNGGFLVRTSLSLVRKILNADCV-LMKCLGNKI-PFEAAVGMNGRVWVKARSNKETIAVANAILASEYMTNEEIKNMCQRL 241
[Close]
BLAST of Exosome complex component RRP40 vs. TrEMBL
Match: R7VC84 (KH_dom_type_1 domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_131167 PE=4 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 8.764e-33
Identity = 86/233 (36.91%), Postives = 137/233 (58.80%), Query Frame = 2 
Query:   95 MPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTA--RKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTI 787
            +PG  +V+ +T    + ++VLG GL     +        VL++  G L F  PN  W++S  K YIPV+G+ ++G +  KSGD ++V+ GG   A L YL F+ ATK NRP+VKIGD ++C+ L+A +  EPEV C++  GKS G+G++    D    +  P    RK+L+ +     K +G   LP+EI IG NG IW+  ++++E + L N+I+ A ++NN  I  + + +
Sbjct:    9 LPGDKIVDKET----DGRIVLGPGLRKETEH--------VLMTKPGKLCFKDPNIYWVDSHHKRYIPVRGENVLGVVTNKSGDTFKVDIGGSEQASLSYLAFEGATKRNRPDVKIGDQVFCKLLVASKHTEPEVVCIDSSGKSNGLGVI---RDGGMTITTPCNHIRKILSPDCV-LLKTLGNS-LPYEIAIGMNGKIWIKGRTTKETIALTNAIACAEYMNNEQISLMCRKL 224
[Close]
BLAST of Exosome complex component RRP40 vs. TrEMBL
Match: A0A210PEF2 (Exosome complex component RRP40 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT08525 PE=4 SV=1)

HSP 1 Score: 130.568 bits (327), Expect = 3.789e-32
Identity = 80/237 (33.76%), Postives = 137/237 (57.81%), Query Frame = 2 
Query:   95 MPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGT--GILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRGM 799
            +PG I+  +    E   K++LG GL         +    +  +  G+L+  +PN  W++S  K YIPVKGD ++G +  K+GD ++V+ G    A L Y+ F+ ATK NRP+VK+GD++YC+F+ A + +E EV C++  GKS G+G++  +   ++QV +   RK+L+    P C+  G+    + +E  +G NG IW+ AK+  E + + N+I  + ++ N+ IK + K +   M
Sbjct:   10 LPGEIVTGFKA-SEKTSKVILGPGLR--------QETETIRATKPGILRHKEPNIYWVDSHQKRYIPVKGDTVLGIVTAKAGDIFRVDVGSSDQASLPYVAFEAATKRNRPDVKVGDIVYCKFVEANKDMEGEVVCIDSSGKSGGLGVIGRDAGYLFQVPINLTRKVLS----PDCELFGSLGKNMRYETAVGMNGRIWVKAKTVVETIAITNAICASEYMTNTEIKNMCKRLADSM 233
[Close]
BLAST of Exosome complex component RRP40 vs. TrEMBL
Match: A0A1A9WZZ3 (KH_dom_type_1 domain-containing protein OS=Glossina brevipalpis OX=37001 PE=4 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 6.582e-32
Identity = 79/231 (34.20%), Postives = 126/231 (54.55%), Query Frame = 2 
Query:   95 MPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTI 787
            MPG  +   + L     K++LG GL  +++         V+   SG L F +PN  W++S  + YIP + + +IG +  K GD ++V+ G P  A L YL F++A+K NRP+V +GD++Y   ++A +  EPE+ CVN  GK   +G++  NE  ++   L  AR +L  E  P    + T  +P EI +G NG IW+ AKS +E + + N+I      +   I +L + I
Sbjct:    6 MPGDRIQAAEVLAAAGKKVILGPGLRRVDDKQ-------VMACKSGTLHFKEPNTFWVDSYQRRYIPARSELVIGVVTAKVGDLFRVDIGAPEQASLSYLAFEQASKKNRPDVNLGDLLYARLVVANKDFEPELVCVNSSGKKGKLGVL--NEGFVFNCSLNLARLILR-EDCPLLNAL-TKEMPFEIAVGMNGRIWIKAKSIKETIAVGNAILATEFSSKEQIAKLCQNI 225
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Cavefish
Match: exosc3 (exosome component 3 [Source:NCBI gene;Acc:103035868])

HSP 1 Score: 119.783 bits (299), Expect = 1.853e-31
Identity = 70/200 (35.00%), Postives = 120/200 (60.00%), Query Frame = 2 
Query:  197 ENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRG 796
             N   +L+  SG+L+   PN  WI+S  K Y+PVKG+ +IG +  KSGD ++V+ GG   A L YL F+ ATK NRPNV++GD++Y +F +A + +EPE+ C++  G++ GMG+   +   +++V L   R+LL  +S    K +   I P E+++G NG +W+ AK+ ++ + + N +    ++     + L + +  G
Sbjct:   47 RNGDEILVYKSGILRHKAPNLYWIDSQQKRYVPVKGESVIGIVTAKSGDIFKVDVGGSEQASLSYLAFEGATKRNRPNVQVGDLVYAQFTIANKDMEPELVCIDSCGRANGMGVFGAD-GLLFKVSLGLVRRLLAPQS-EIVKDL-EKIFPFEMVVGLNGRVWVKAKTVQQTLIVANLLESCENMTTQQRQVLFRRVAEG 243
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Sea Lamprey
Match: exosc3 (exosome component 3 [Source:ZFIN;Acc:ZDB-GENE-050706-140])

HSP 1 Score: 109.383 bits (272), Expect = 4.115e-28
Identity = 76/222 (34.23%), Postives = 128/222 (57.66%), Query Frame = 2 
Query:  146 KLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFC---KKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHI---KQLIKTIRR 793
            ++VLG GL       + E +V VL    GVL+  +P+  W+ES  K Y+PVKG+ +IG +  ++GD ++V+ GG   A L +L F+ ATK NRPNV++ D+++   L+A + +EPE+ C++  G++ GMG++      +    L  AR+LL     P C   +++G    P EI+ G NG +W+ A++ R      N++ +AS +++S     +QL   + R
Sbjct:   44 RVVLGPGL-------RREGEV-VLACRCGVLRHREPHTYWVESHQKRYVPVKGETVIGVVTARAGDVFKVDVGGSEQASLSFLAFEGATKRNRPNVQVADLVFGRLLVANKDMEPELVCMDSGGRASGMGVLGPG-GFLLHCSLGLARRLLQ----PDCEILRRLGAA-FPMEIVAGMNGRVWVKARTVR------NTLLVASLLDSSEFMSPRQLQAALAR 245
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Yeast
Match: RRP40 (Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain both S1 and KH RNA binding domains; mutations in the human homolog, EXOSC3, cause pontocerebellar hypoplasia with motor neuron degeneration [Source:SGD;Acc:S000005502])

HSP 1 Score: 66.6254 bits (161), Expect = 3.255e-13
Identity = 53/162 (32.72%), Postives = 82/162 (50.62%), Query Frame = 2 
Query:  224 HSGVLKFSKPNR-----IWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGG-PCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNE-IGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWL 688
            ++GVL  S   +      +I+ +SK YIP   D +IG I+    D Y+V          L Y+ F  A+K NRP +++GD++Y     A + +E E+ C +   G+  G GI++  +  I  V+L  AR+LL    FP  K +       E+ IG NG IW+
Sbjct:   38 NTGVLHVSAKGKSGVQTAYIDYSSKRYIPSVNDFVIGVIIGTFSDSYKVSLQNFSSSVSLSYMAFPNASKKNRPTLQVGDLVYARVCTAEKELEAEIECFDSTTGRDAGFGILE--DGMIIDVNLNFARQLLFNNDFPLLKVLAAHT-KFEVAIGLNGKIWV 196
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Nematostella
Match: EDO36096 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJP6])

HSP 1 Score: 105.145 bits (261), Expect = 1.826e-26
Identity = 74/219 (33.79%), Postives = 121/219 (55.25%), Query Frame = 2 
Query:  146 KLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRGMF 802
            KL LG GL         +    VL   SGV +   P   WI++  K Y+PVK +++IG I  + G+ Y+V+ G    A L  L F+ ATK N+PN++IGD++YC   +A + +EPE+ C +  GKS G+G +      ++   L   RKLLN + F   K +G    P E  +G NG +W++AK++   + + N+IS +  ++N  I+ +++ +  G+ 
Sbjct:   34 KLKLGPGLR--------QEGEQVLAYKSGVFRHRAPAVYWIDTNQKRYVPVKDERVIGIISNRGGESYKVDIGTSNPATLSSLAFEGATKRNKPNLQIGDLVYCRLSIANKDMEPELDCTDGSGKSTGLGPLSGG--FMFNCSLGLTRKLLN-KDFILLKLLGK-YFPFECTVGLNGRVWINAKTTINIIAISNAISNSEFMDNQQIETMVRQLVEGIM 240
[Close]
BLAST of Exosome complex component RRP40 vs. Ensembl Medaka
Match: exosc3 (exosome component 3 [Source:NCBI gene;Acc:101170911])

HSP 1 Score: 112.079 bits (279), Expect = 1.829e-28
Identity = 64/195 (32.82%), Postives = 114/195 (58.46%), Query Frame = 2 
Query:  212 VLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRG 796
            +++  SGVL+   P   WI+S  K Y+  KG+ +IG +  ++GD ++V+FGG   A L YL F+ ATK NRPNV++GD+++ +FL+A + +EPE+ C++  G++ GMG        + +V L   R+LL   S    +     + P E+++G NG +W+ A S ++ + + N +     +     +QL + +++G
Sbjct:   57 LVVMKSGVLRHKPPLTFWIDSQQKRYVATKGETVIGIVTARAGDTFRVDFGGSELASLSYLAFEGATKRNRPNVQVGDLVFAQFLIANKDMEPELVCIDGSGRANGMGAFGAG-GLLIKVSLGLVRRLLAPNS--DIRLDLEQLFPCELVVGMNGRVWVRASSVQQTLIVANLLQSCDTMTTQQRQQLFRRVQQG 248
[Close]
BLAST of Exosome complex component RRP40 vs. Planmine SMEST
Match: SMESG000002729.1 (SMESG000002729.1)

HSP 1 Score: 453.751 bits (1166), Expect = 6.504e-162
Identity = 241/242 (99.59%), Postives = 241/242 (99.59%), Query Frame = 2 
Query:   89 FYMPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPXXXXXXXXXXXXXXXXYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRGMFCNDK 814
            FYMPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPN IWIESTSKIYIPVKGDKIIGKIVKKSGDYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRGMFCNDK
Sbjct:   15 FYMPGVILVEYDTLYELEDKLVLGFGLEVIENYSKLENKVAVLISHSGVLKFSKPNCIWIESTSKIYIPVKGDKIIGKIVKKSGDYYQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEVTCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGILPHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRGMFCNDK 256
The following BLAST results are available for this feature:
BLAST of Exosome complex component RRP40 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
EXOSC33.184e-2936.32exosome component 3 [Source:HGNC Symbol;Acc:HGNC:1... [more]
EXOSC36.630e-643.21exosome component 3 [Source:HGNC Symbol;Acc:HGNC:1... [more]
EXOSC36.630e-643.21exosome component 3 [Source:HGNC Symbol;Acc:HGNC:1... [more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
exos-39.395e-2231.55EXOSome (Multiexonuclease complex) component [Sou... [more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Rrp401.063e-2934.80gene:FBgn0260648 transcript:FBtr0077883[more]
Rrp401.063e-2934.80gene:FBgn0260648 transcript:FBtr0345430[more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
exosc36.200e-2930.73exosome component 3 [Source:ZFIN;Acc:ZDB-GENE-0507... [more]
exosc31.049e-2830.73exosome component 3 [Source:ZFIN;Acc:ZDB-GENE-0507... [more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
EXOSC32.319e-2836.70exosome component 3 [Source:NCBI gene;Acc:10049127... [more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Exosc31.134e-2736.00exosome component 3 [Source:MGI Symbol;Acc:MGI:191... [more]
Exosc32.680e-1638.18exosome component 3 [Source:MGI Symbol;Acc:MGI:191... [more]
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BLAST of Exosome complex component RRP40 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9NQT5|EXOS3_HUMAN1.529e-2836.32Exosome complex component RRP40 OS=Homo sapiens OX... [more]
sp|Q3T0E1|EXOS3_BOVIN4.834e-2836.32Exosome complex component RRP40 OS=Bos taurus OX=9... [more]
sp|Q7TQK4|EXOS3_MOUSE7.931e-2736.00Exosome complex component RRP40 OS=Mus musculus OX... [more]
sp|Q7KWX9|EXOS3_DICDI8.687e-2331.17Putative exosome complex component rrp40 OS=Dictyo... [more]
sp|O13903|RRP40_SCHPO6.486e-1828.99Exosome complex component rrp40 OS=Schizosaccharom... [more]
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BLAST of Exosome complex component RRP40 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1PH061.657e-3538.94Exosome complex exonuclease RRP40 OS=Crassostrea g... [more]
A0A2T7NS462.146e-3437.38KH_dom_type_1 domain-containing protein OS=Pomacea... [more]
R7VC848.764e-3336.91KH_dom_type_1 domain-containing protein OS=Capitel... [more]
A0A210PEF23.789e-3233.76Exosome complex component RRP40 OS=Mizuhopecten ye... [more]
A0A1A9WZZ36.582e-3234.20KH_dom_type_1 domain-containing protein OS=Glossin... [more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
exosc31.853e-3135.00exosome component 3 [Source:NCBI gene;Acc:10303586... [more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
exosc34.115e-2834.23exosome component 3 [Source:ZFIN;Acc:ZDB-GENE-0507... [more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
RRP403.255e-1332.72Exosome non-catalytic core component; involved in ... [more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO360961.826e-2633.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Exosome complex component RRP40 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
exosc31.829e-2832.82exosome component 3 [Source:NCBI gene;Acc:10117091... [more]
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BLAST of Exosome complex component RRP40 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000002729.16.504e-16299.59SMESG000002729.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006169 ID=SMED30006169|Name=Exosome complex component RRP40|organism=Schmidtea mediterranea sexual|type=transcript|length=1085bp
AAATCATCGAAAATTAAATTGTTTAAATATTGCTTATTTCTGAAAAATGA
ATGAAAATTTATCTGAATTAAATGAAAAATTAAATAATTTTTATATGCCT
GGTGTGATCTTGGTGGAATATGATACTTTGTACGAATTAGAAGATAAACT
TGTTTTAGGTTTCGGTCTCGAAGTTATTGAAAATTACTCAAAGTTGGAAA
ACAAAGTTGCTGTCTTAATATCACATTCAGGCGTTTTGAAATTTTCAAAA
CCAAATCGTATTTGGATCGAATCCACAAGTAAAATTTATATTCCTGTCAA
GGGTGATAAAATAATTGGAAAAATTGTGAAAAAGTCTGGTGATTATTATC
AAGTAGAATTCGGTGGTCCATGTTGTGCTCAACTGTATTATTTAAACTTC
CAAGAAGCTACTAAAAACAATAGACCAAATGTGAAAATTGGCGATGTAAT
ATATTGCGAATTTCTACTGGCCGGTCGAGGTATTGAACCCGAAGTTACTT
GTGTAAATGAGATAGGAAAATCTATTGGAATGGGAATAGTGGATCACAAT
GAAGATTCAATTTACCAAGTTGATTTACCAACAGCAAGAAAGTTGTTAAA
TATCGAATCATTTCCATTTTGTAAAAAGATTGGAACTGGTATTCTGCCCC
ATGAAATTATAATAGGAAGTAACGGATGGATTTGGTTATCTGCGAAATCT
AGTCGGGAATATGTGACATTGATCAATTCCATTTCACTAGCCAGCCACGT
AAATAACTCACACATTAAACAACTGATCAAAACCATCCGCCGAGGAATGT
TTTGTAACGATAAATAAATTTTAAATGTTGATCATTTTGCTACTACGAAT
TGAATATAGATTTCGGCATTTATAAACTTTAATTAGATATGAATTTTGAT
TTTTTTTGTTTATTTGTATGAAATTATTGGTGGAATGATGCTTGATTTAT
TTGTTATTTGGAAGTTTAAAAATATTTATCTATGTATTCGTGTATGGTTT
TATATATTTTGTCTCCAATTATCCTTTCGACGCTTTTAACCATTATACTA
GAAATCAATAAATTTTTGTTTTGCTTCAAAAAAAA
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protein sequence of SMED30006169-orf-1

>SMED30006169-orf-1 ID=SMED30006169-orf-1|Name=SMED30006169-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=257bp
MNENLSELNEKLNNFYMPGVILVEYDTLYELEDKLVLGFGLEVIENYSKL
ENKVAVLISHSGVLKFSKPNRIWIESTSKIYIPVKGDKIIGKIVKKSGDY
YQVEFGGPCCAQLYYLNFQEATKNNRPNVKIGDVIYCEFLLAGRGIEPEV
TCVNEIGKSIGMGIVDHNEDSIYQVDLPTARKLLNIESFPFCKKIGTGIL
PHEIIIGSNGWIWLSAKSSREYVTLINSISLASHVNNSHIKQLIKTIRRG
MFCNDK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR004088KH_dom_type_1
IPR012340NA-bd_OB-fold
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
Vocabulary: cellular component
TermDefinition
GO:0000178exosome (RNase complex)