HTH CENPB-type domain-containing protein

Overview
NameHTH CENPB-type domain-containing protein
Smed IDSMED30006150
Length (bp)4230
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of HTH CENPB-type domain-containing protein (SMED30006150) t-SNE clustered cells

Violin plots show distribution of expression levels for HTH CENPB-type domain-containing protein (SMED30006150) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HTH CENPB-type domain-containing protein (SMED30006150) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for HTH CENPB-type domain-containing protein (SMED30006150) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006150

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30006150 SmedASXL_015439SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
gutSMED30006150SMESG000047012.1 SMESG000047013.1 dd_Smed_v4_1450_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30006150SMESG000081298.1 SMESG000023765.1 SMESG000016276.1 SMESG000004841.1 dd_Smed_v4_8652_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30006150SMESG000081298.1 SMESG000023765.1 SMESG000016276.1 SMESG000004841.1 dd_Smed_v4_8652_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006150SMESG000081298.1 SMESG000023765.1 SMESG000016276.1 SMESG000004841.1 dd_Smed_v4_8652_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30006150SMESG000081298.1 SMESG000023765.1 SMESG000016276.1 SMESG000004841.1 dd_Smed_v4_8652_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30006150SMESG000081298.1 SMESG000023765.1 SMESG000016276.1 SMESG000004841.1 dd_Smed_v4_8652_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30006150 Contig25305newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30006150SMESG000047012.1 SMESG000047013.1 dd_Smed_v4_1450_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: TIGD1 (tigger transposable element derived 1 [Source:HGNC Symbol;Acc:HGNC:14523])

HSP 1 Score: 172.17 bits (435), Expect = 2.718e-67
Identity = 92/205 (44.88%), Postives = 128/205 (62.44%), Query Frame = 3 
Query: 1158 F*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSN------QCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIED 1754
            F ++KDRLTLL+G N  GDF++KP+LIYHSENPRA+K  +K +L V++  N K+ MT+ L+     +  F         +K+I  K LL++DNAP HP+ + E      + +IF P NTTSILQPMDQGVI+TFK+YY+R TF +    +DS+      Q   K FWK F I++  +NI  SW EV+ + L G  + L    I+D
Sbjct:  212 FKASKDRLTLLLGANAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFT-AWFTEYFKPTVETYCSEKKIPFKILLLIDNAPSHPRALMEIYE--EINVIFMPANTTSILQPMDQGVISTFKSYYLRNTFHKALAAMDSDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKLSTLTGVWKKLIPTLIDD 413

HSP 2 Score: 54.6842 bits (130), Expect = 2.718e-67
Identity = 38/109 (34.86%), Postives = 59/109 (54.13%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFIICQENNT----QKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLK 872
            ++SR SL L  K+ +I+  E G  ++E   RLGL   T+  ++   +    +       NT    ++ S +  MEK+L  WI+DQT RN+PLSQ +I  KA  L+  +K
Sbjct:    9 RKSRTSLTLNQKLEMIKLSEEGMSKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKSATPMNTRMIRKRNSLIADMEKVLVVWIEDQTSRNIPLSQSLIQNKALTLFNSMK 117

HSP 3 Score: 45.8246 bits (107), Expect = 2.718e-67
Identity = 24/54 (44.44%), Postives = 33/54 (61.11%), Query Frame = 1 
Query: 1012 FEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFNPRK 1173
            + ++L  I  +  Y +  IFN DET    +WKKMPS+ FI++EEKS  GF   K
Sbjct:  165 YPEALAKIIDEGGYTKQQIFNVDETAF--YWKKMPSRTFIAREEKSVPGFKASK 216

HSP 4 Score: 39.2762 bits (90), Expect = 2.718e-67
Identity = 26/91 (28.57%), Postives = 46/91 (50.55%), Query Frame = 2 
Query: 1847 LIESDDHGIYNEDLFASLSQI*PEIADNTLETEDITEII-LTKKCLEYNLRIIQNSLEDLSENDPNFERSCAIKLGVMNTLSPYTEILKEK 2116
            L++S D  + +E+LF   +Q    +   +   ED   I+ +T K LEY + ++  +       D NFERS  +   + N+++ Y EI  E+
Sbjct:  447 LLQSHDKTLTDEELFLMDAQRKWFLEMESTPGEDAVNIVEMTTKDLEYYINLVDKAAAGFERIDSNFERSSTVGKMLSNSIACYREIFHER 537

HSP 5 Score: 28.4906 bits (62), Expect = 2.718e-67
Identity = 9/19 (47.37%), Postives = 13/19 (68.42%), Query Frame = 2 
Query:  920 GWFEKFKLRANLHSISRSG 976
            GWF +FK R++ H+I   G
Sbjct:  134 GWFMRFKERSHFHNIKAQG 152
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: JRKL (JRK like [Source:HGNC Symbol;Acc:HGNC:6200])

HSP 1 Score: 74.7146 bits (182), Expect = 2.688e-19
Identity = 48/175 (27.43%), Postives = 85/175 (48.57%), Query Frame = 3 
Query: 1164 SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSW 1688
            S ++R+T++   N TG  ++K  ++  ++ PR+ K     +L V + + + +WM   ++      + F+      LR K + +KA+L+LDN+P HP           +   + P N  S++QP DQGVIAT K  Y     +   +E +      K FWK   +++    I  +W
Sbjct:  204 SIEERVTIMCCANATGLHKLKLCVVGKAKKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFR-QWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPSDQGVIATMKRNYRAGLLQNNLEEGN----DLKSFWKKLTLLDALYEIAMAW 373

HSP 2 Score: 32.7278 bits (73), Expect = 2.688e-19
Identity = 23/112 (20.54%), Postives = 56/112 (50.00%), Query Frame = 3 
Query:  552 NGKQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNL------YNKFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGL 869
            +GK+ R  L ++ K+++I+++E G    + +   G+  +T+  I KN + +       +   +  +  + K S  E++++ +  W + Q  +  P+S  I  ++A+  +  L
Sbjct:    2 SGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDRAMLEWFNQQRAKGNPISGPICAKRAEFFFYAL 113

HSP 3 Score: 28.1054 bits (61), Expect = 2.688e-19
Identity = 18/61 (29.51%), Postives = 31/61 (50.82%), Query Frame = 1 
Query:  976 ESASADKESSKVFEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASG 1158
            E  + D+ + + F  +  D  ++ N     I+N DET    FWK +PS+I + K + +  G
Sbjct:  143 ERLNGDETAVEDFCNNFRDFIERENLQPEQIYNADETG--LFWKCLPSRISVIKGKCTVPG 201

HSP 4 Score: 20.7866 bits (42), Expect = 2.688e-19
Identity = 8/21 (38.10%), Postives = 12/21 (57.14%), Query Frame = 2 
Query:  905 FVPR*GWFEKFKLRANLHSIS 967
            F P  GW  +FK R ++  I+
Sbjct:  119 FNPSAGWLTRFKQRHSIREIN 139
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: TIGD2 (tigger transposable element derived 2 [Source:HGNC Symbol;Acc:HGNC:18333])

HSP 1 Score: 79.337 bits (194), Expect = 2.253e-14
Identity = 90/407 (22.11%), Postives = 178/407 (43.73%), Query Frame = 3 
Query:  555 GKQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYN------KFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILY--LGLKNRTEECSTADSLFQDEAGL-----KSLNYVQTYTALVVPGICQC**RIFKGI*EEFV*Y*KTIKLSSASYF*F**NLLMRFLEENAIKNIHLQRRKICFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLF 1736
            GK+ R  L ++ K+++I+++E G    + S   G+  ST+  I KN + + N            +  + K S  E++++++  W + Q    +P+S  I  ++AK  +  LG++      S   + F+   G+     K        TA           R F G  +EFV   +   L     +    +    F +    + + L+  +      S+++R+ ++   N TG  ++   ++  ++ PRA KG    +L V + + + +W+   ++      + F+      L+ K + +KA+L+LD  P  P           + + + P N TS++QPM QGV+AT K YY     ++   E +  +     FWKN  +++    +  +W  V+ + +    + LF
Sbjct:    3 GKRKRVVLTIKDKLDIIKKLEEGISFKKLSVVYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAA----------REFCGSFQEFV---EKENLQPEQIYGA--DQTGLFWKCLPSRTLTLETDQSTSGCRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQKGAWIEQSVFR-QWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYYRAGLLQKYMDEGNDPKI----FWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLF 389
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: TIGD2 (tigger transposable element derived 2 [Source:HGNC Symbol;Acc:HGNC:18333])

HSP 1 Score: 79.337 bits (194), Expect = 2.253e-14
Identity = 90/407 (22.11%), Postives = 178/407 (43.73%), Query Frame = 3 
Query:  555 GKQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYN------KFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILY--LGLKNRTEECSTADSLFQDEAGL-----KSLNYVQTYTALVVPGICQC**RIFKGI*EEFV*Y*KTIKLSSASYF*F**NLLMRFLEENAIKNIHLQRRKICFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLF 1736
            GK+ R  L ++ K+++I+++E G    + S   G+  ST+  I KN + + N            +  + K S  E++++++  W + Q    +P+S  I  ++AK  +  LG++      S   + F+   G+     K        TA           R F G  +EFV   +   L     +    +    F +    + + L+  +      S+++R+ ++   N TG  ++   ++  ++ PRA KG    +L V + + + +W+   ++      + F+      L+ K + +KA+L+LD  P  P           + + + P N TS++QPM QGV+AT K YY     ++   E +  +     FWKN  +++    +  +W  V+ + +    + LF
Sbjct:    3 GKRKRVVLTIKDKLDIIKKLEEGISFKKLSVVYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAA----------REFCGSFQEFV---EKENLQPEQIYGA--DQTGLFWKCLPSRTLTLETDQSTSGCRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQKGAWIEQSVFR-QWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYYRAGLLQKYMDEGNDPKI----FWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLF 389
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Match: TIGD7 (tigger transposable element derived 7 [Source:HGNC Symbol;Acc:HGNC:18331])

HSP 1 Score: 78.1814 bits (191), Expect = 5.286e-14
Identity = 63/219 (28.77%), Postives = 105/219 (47.95%), Query Frame = 3 
Query: 1119 KNIHLQRRKICFRF*S-AKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILY----I*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQ---LFQEVDSNQCSNKEFWKNFNIVNVKENI---GSSWLEVQQNCLKGCLEYLFIK 1742
            +N    R+ IC       K+RL+  +  N  G  ++K ++I  S+ P+++K  +  +L VI+  ++  W T  L+        V     +  N+ LR      +ALL+LD+ P HP + S       ++ +F P NT++++QPM+QGVI + K  Y  K  ++   +F+E D  Q    +      I N+K  I     SW EV+Q  +    E L  K
Sbjct:  189 ENSQASRKDICLPGKKINKERLSAFLCANADGTHKLKSIIIGKSKLPKSVKEDT-STLPVIYKPSKDVWFTRELFSEWFFQNFVPEVRHFQLNV-LRFHDEDVRALLLLDSCPAHPSSESLTSEDGRIKCMFFPHNTSTLIQPMNQGVILSCKRLYRWKQLEESLVIFEESDDEQEKGDKGVSKIKIYNIKSAIFNWAKSWEEVKQITIANAWENLLYK 405
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Xenopus
Match: kif6 (kinesin family member 6 [Source:Xenbase;Acc:XB-GENE-1014042])

HSP 1 Score: 75.0998 bits (183), Expect = 7.167e-13
Identity = 94/396 (23.74%), Postives = 178/396 (44.95%), Query Frame = 3 
Query:  573 SLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFI------ICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLKNRTEECSTADS---LFQDEAGLK--SLNYVQTYTAL-VVPGICQC**RIFKGI*EEFV*Y*KTIKLSSASYF*F**NLLMRFLEENAIKNIHLQRRKICFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSIL----YI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCL 1712
            SL+++ K+ +++ +E+G        + G+  STI  + K  D L   +       +  +  T  +++   ++K+L  WI  + + N PLS+ +IM +AK  ++ L N +  C  +      F+   GL   S+N  +      V     +   ++ K + +E +   +    + AS F        R L +   K +   ++         K+RLT+L   N  G  + + L+I  S NPRA KG+  +   V +  N+++ +T  +    +    V  A  +C ++ L +     K +LILD+ P HP   +EF     V  +  P + TS +QP+DQG++  FK+ Y  +  +++  E +    +  +F    NI +       +W +V +  L
Sbjct:  186 SLSIKDKVTLLQDLENGASVKSLCDKYGIGTSTIYDLKKQKDKLLTFYSNSDAPDLMADRKTLHQAKNVSVDKVLMEWIRQRRRENFPLSRSLIMAQAKKFHV-LLNISTPCEYSSGWYGKFKKRNGLSILSINGEKASEEYNVADNFVK---KLNKLVSDEHLSAEQVYNAAKASLF-------WRHLPQ---KLVATAQKPPSSGLEDPKERLTVLACSNAAGTHKARLLVIGKSRNPRAFKGV--RVFPVTYTANKQAGITREIFQDWFENHFVPEARAHCMSVGLSQD---AKVMLILDHCPTHPS--AEFLVKDNVFAVCLPPDCTSFIQPLDQGILRLFKSNYKSEFLQRMLTECNKGM-AGAQFQAKANIKDAIWTAALAWDKVDKQAL 559
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Xenopus
Match: apmapl (adipocyte plasma membrane associated protein LIKE [Source:Xenbase;Acc:XB-GENE-5754317])

HSP 1 Score: 73.9442 bits (180), Expect = 9.370e-13
Identity = 52/196 (26.53%), Postives = 97/196 (49.49%), Query Frame = 3 
Query: 1173 DRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTC-WPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIEDN 1757
            D +T+L+  N TG  ++KPL++    +P +++  ++     ++  +R +W+T  L     +   F+      L++  + +KA+L+++  PG P    + QT    + ++F  + T S +  MDQGVI++FK  Y R+  K L    DS   S  +F  +F + ++    G SW  +Q   ++ C  Y      E N
Sbjct:  174 DEVTVLLAANLTGSHKLKPLVVGKLRDPPSLRHHNQDKFPAVYHYSRNAWVTQELLREWFLEE-FVPAVKRYLKRCCLQQKAVLLVNQCPGKPPE-EDLQTADGNIRVLFLSKTTRSKIPSMDQGVISSFKQLYRRELLK-LMVSCDS---SPSDFVTSFRLKDMIYLAGQSWNMIQAGSIEKCWLYGLRAAFETN 363
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Match: Jrkl (Jrk-like [Source:MGI Symbol;Acc:MGI:1924782])

HSP 1 Score: 69.3218 bits (168), Expect = 1.240e-18
Identity = 45/174 (25.86%), Postives = 81/174 (46.55%), Query Frame = 3 
Query: 1167 AKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSW 1688
             ++R+T++   N TG  ++K  ++  +  PR+ K     +L V + + + +WM   ++      + F+      LR K + +KA+L+LDN+P HP           +   + P N  S++QP+ QGVIA  K  Y         +E +      K FWK   +++    I  +W
Sbjct:  205 GEERITVMCCTNATGLHKLKLCVVGKARKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFR-QWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPLGQGVIAAMKRNYRAGLLHNNLEEGN----DLKSFWKKLTLLDALYEIAMAW 373

HSP 2 Score: 33.4982 bits (75), Expect = 1.240e-18
Identity = 24/112 (21.43%), Postives = 56/112 (50.00%), Query Frame = 3 
Query:  552 NGKQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNL------YNKFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGL 869
            +GK+ R  L ++ K+++I+++E G    + +   G+  +T+  I KN + +       +   +  +  + K S  E+++K +  W + Q  +  P+S  I  ++A+  +  L
Sbjct:    2 SGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDKAMLEWFNQQRAKGNPISGPICAKRAEFFFYAL 113

HSP 3 Score: 30.0314 bits (66), Expect = 1.240e-18
Identity = 19/63 (30.16%), Postives = 31/63 (49.21%), Query Frame = 1 
Query:  976 ESASADKESSKVFEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFN 1164
            E  + D+ + + F  +  D  +Q N     I+N DET    FWK +PS+  + K + +  G N
Sbjct:  143 ERLNGDETAVEDFCNNFRDFIEQENLQPEQIYNADETG--LFWKCLPSRTTVIKGKCTVPGHN 203

HSP 4 Score: 20.7866 bits (42), Expect = 1.240e-18
Identity = 8/21 (38.10%), Postives = 12/21 (57.14%), Query Frame = 2 
Query:  905 FVPR*GWFEKFKLRANLHSIS 967
            F P  GW  +FK R ++  I+
Sbjct:  119 FNPSAGWLTRFKQRHSIREIN 139
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Match: Tigd2 (tigger transposable element derived 2 [Source:MGI Symbol;Acc:MGI:1915390])

HSP 1 Score: 77.0258 bits (188), Expect = 9.264e-14
Identity = 89/401 (22.19%), Postives = 174/401 (43.39%), Query Frame = 3 
Query:  567 RKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYN------KFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILY--LGLKNRTEECSTADSLFQDEAGLKSLNYVQTYTALVVPGICQC**RIFKGI*EEFV*Y*KTIKLSSASYF*F**NLLMRFLEENAIKNIHLQRRKICFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMT-SILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEII--FTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLF 1736
            R  L ++ K+++I+++E G    + S   G+  ST+  I KN + + N            +  + K S  E++++++  W + Q    +P+S  I  ++A+  +  LG++      S   + F+   G+       T          +     F G  +EFV   +   L    Y      L  + L     + +     +    + ++++R+ ++   N TG  ++   ++  ++ PRA KG    +L V + + + +W+  S+L       + F+      L+ K + +KA+L+LD    HP    E  +     II  + P N TS++QPM QGV+ T K YY     ++   E +      K FWKN  +++       +W +++ N +    + LF
Sbjct:    7 RVVLTIKDKLDIIKKLEEGNSFKKLSVLYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQARFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAASE-----FCGNFQEFVE--RENLLPEQIYGADQTGLFWKCL---PTRTLAFDTDQSTCEYRTSRERIIIMCCANATGSHKLNLCVVGKAKRPRAFKGTDLSNLPVTYFSQKSAWIEPSVLK--QWFEKCFVPQVQKHLKSKGLREKAVLLLDFPAAHP--AEELLSSDDGRIIVKYLPPNVTSLIQPMSQGVLTTVKRYYRAGLIQKYMDEGN----DPKTFWKNLTVLDAIYEASRAWNQIRSNTITRAWKKLF 389
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Match: Jrk (jerky [Source:MGI Symbol;Acc:MGI:106214])

HSP 1 Score: 68.1662 bits (165), Expect = 5.075e-11
Identity = 96/366 (26.23%), Postives = 157/366 (42.90%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFI------ICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLKNRTEECSTADS---LFQDEAGLKSLNYVQTYTALVVPGICQ-C**RIFKGI*EEFV*Y*KTIKLSSASYF*F**NLLMRFLEENAIKNIHLQRRKICFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRK--KRIG----KKALLILDNAPGHPQN---VSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLF 1598
            K+ R  L L+ K+++  R+E GE +        +  ST+  I  +   L   F         ++  T    +LE ++++L  W   +    +P+S  +++EKAK  Y  ++  TE C  +      F+   G+K L+      A       Q C    F+ +  E     + +  +  +       L+ R L  +A  +           F   KDRLT+L+  N TG  R+KPL I     PRA +GI  Q L + +     +W+   ++     S  F +     +R+  + IG     KA+L+LD++  H Q    VSE      V  IF P + TS+LQP +QG         IR+ F +LF
Sbjct:   14 KRKRVVLTLKEKIDICTRLERGESRKALMQEYNVGMSTLYDIKAHKAQLLRFFASSDSRQALEQRRTLHTPKLEHLDRVLYEWFLVKRAEGIPVSGPMLIEKAKDFYKQMR-LTEPCVFSGGWLWRFKARHGIKKLDASSEKQAADHQAAEQFC--GFFRSLAAEHGLSPEQVYSADET------GLVWRCLPNSAPDD------GTVPHFKQGKDRLTVLMCANATGSHRIKPLAIGKGGGPRAFRGI--QHLPIAYKAQGNAWVDKEIF-----SDWFHHIFVPSVREHFRTIGLPEDSKAILLLDHSRAHSQESELVSEN-----VFTIFLPSSVTSLLQPTEQG---------IRRAFMRLF 343
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Match: Tigd4 (tigger transposable element derived 4 [Source:MGI Symbol;Acc:MGI:2685264])

HSP 1 Score: 67.3958 bits (163), Expect = 7.645e-11
Identity = 61/209 (29.19%), Postives = 97/209 (46.41%), Query Frame = 3 
Query: 1083 NLLMRFLEEN--AIKNIHLQRRKICFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VM--VSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEV 1697
             LL R L  N  A K       K+C      KDR+TL +G N  G  ++  L+I  +  PR  KGI  +SL V +  NR +WMT+ ++   M  +   F        +K+R+    ++ +D+ P HP    E +    +E+ F P   +S    M+QGVI + K  Y     K+    V+    S+KEF   F++++  + +   W  V
Sbjct:  186 GLLYRMLPTNTFAFKGETCSVGKLC------KDRITLALGTNMDGSEKLPLLIIGKNRAPRCFKGI--KSLPVYYEANRTAWMTAAIFEQWMQKLDEKFQ------AQKRRV----VIFVDSCPAHP----EVKNLKSIELAFFPSCLSSGFAAMNQGVIKSLKIKYRHCLIKKFLSSVE----SSKEF--TFSLLDAVDTLHLCWRAV 366
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96MW7|TIGD1_HUMAN (Tigger transposable element-derived protein 1 OS=Homo sapiens OX=9606 GN=TIGD1 PE=1 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 1.204e-66
Identity = 92/205 (44.88%), Postives = 128/205 (62.44%), Query Frame = 3 
Query: 1158 F*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSN------QCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIED 1754
            F ++KDRLTLL+G N  GDF++KP+LIYHSENPRA+K  +K +L V++  N K+ MT+ L+     +  F         +K+I  K LL++DNAP HP+ + E      + +IF P NTTSILQPMDQGVI+TFK+YY+R TF +    +DS+      Q   K FWK F I++  +NI  SW EV+ + L G  + L    I+D
Sbjct:  212 FKASKDRLTLLLGANAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFT-AWFTEYFKPTVETYCSEKKIPFKILLLIDNAPSHPRALMEIYE--EINVIFMPANTTSILQPMDQGVISTFKSYYLRNTFHKALAAMDSDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKLSTLTGVWKKLIPTLIDD 413

HSP 2 Score: 54.6842 bits (130), Expect = 1.204e-66
Identity = 38/109 (34.86%), Postives = 59/109 (54.13%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFIICQENNT----QKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLK 872
            ++SR SL L  K+ +I+  E G  ++E   RLGL   T+  ++   +    +       NT    ++ S +  MEK+L  WI+DQT RN+PLSQ +I  KA  L+  +K
Sbjct:    9 RKSRTSLTLNQKLEMIKLSEEGMSKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKSATPMNTRMIRKRNSLIADMEKVLVVWIEDQTSRNIPLSQSLIQNKALTLFNSMK 117

HSP 3 Score: 45.8246 bits (107), Expect = 1.204e-66
Identity = 24/54 (44.44%), Postives = 33/54 (61.11%), Query Frame = 1 
Query: 1012 FEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFNPRK 1173
            + ++L  I  +  Y +  IFN DET    +WKKMPS+ FI++EEKS  GF   K
Sbjct:  165 YPEALAKIIDEGGYTKQQIFNVDETAF--YWKKMPSRTFIAREEKSVPGFKASK 216

HSP 4 Score: 39.2762 bits (90), Expect = 1.204e-66
Identity = 26/91 (28.57%), Postives = 46/91 (50.55%), Query Frame = 2 
Query: 1847 LIESDDHGIYNEDLFASLSQI*PEIADNTLETEDITEII-LTKKCLEYNLRIIQNSLEDLSENDPNFERSCAIKLGVMNTLSPYTEILKEK 2116
            L++S D  + +E+LF   +Q    +   +   ED   I+ +T K LEY + ++  +       D NFERS  +   + N+++ Y EI  E+
Sbjct:  447 LLQSHDKTLTDEELFLMDAQRKWFLEMESTPGEDAVNIVEMTTKDLEYYINLVDKAAAGFERIDSNFERSSTVGKMLSNSIACYREIFHER 537

HSP 5 Score: 28.4906 bits (62), Expect = 1.204e-66
Identity = 9/19 (47.37%), Postives = 13/19 (68.42%), Query Frame = 2 
Query:  920 GWFEKFKLRANLHSISRSG 976
            GWF +FK R++ H+I   G
Sbjct:  134 GWFMRFKERSHFHNIKAQG 152
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Y4A0|JERKL_HUMAN (Jerky protein homolog-like OS=Homo sapiens OX=9606 GN=JRKL PE=2 SV=2)

HSP 1 Score: 74.7146 bits (182), Expect = 1.192e-18
Identity = 48/175 (27.43%), Postives = 85/175 (48.57%), Query Frame = 3 
Query: 1164 SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSW 1688
            S ++R+T++   N TG  ++K  ++  ++ PR+ K     +L V + + + +WM   ++      + F+      LR K + +KA+L+LDN+P HP           +   + P N  S++QP DQGVIAT K  Y     +   +E +      K FWK   +++    I  +W
Sbjct:  204 SIEERVTIMCCANATGLHKLKLCVVGKAKKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFR-QWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPSDQGVIATMKRNYRAGLLQNNLEEGN----DLKSFWKKLTLLDALYEIAMAW 373

HSP 2 Score: 32.7278 bits (73), Expect = 1.192e-18
Identity = 23/112 (20.54%), Postives = 56/112 (50.00%), Query Frame = 3 
Query:  552 NGKQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNL------YNKFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGL 869
            +GK+ R  L ++ K+++I+++E G    + +   G+  +T+  I KN + +       +   +  +  + K S  E++++ +  W + Q  +  P+S  I  ++A+  +  L
Sbjct:    2 SGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDRAMLEWFNQQRAKGNPISGPICAKRAEFFFYAL 113

HSP 3 Score: 28.1054 bits (61), Expect = 1.192e-18
Identity = 18/61 (29.51%), Postives = 31/61 (50.82%), Query Frame = 1 
Query:  976 ESASADKESSKVFEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASG 1158
            E  + D+ + + F  +  D  ++ N     I+N DET    FWK +PS+I + K + +  G
Sbjct:  143 ERLNGDETAVEDFCNNFRDFIERENLQPEQIYNADETG--LFWKCLPSRISVIKGKCTVPG 201

HSP 4 Score: 20.7866 bits (42), Expect = 1.192e-18
Identity = 8/21 (38.10%), Postives = 12/21 (57.14%), Query Frame = 2 
Query:  905 FVPR*GWFEKFKLRANLHSIS 967
            F P  GW  +FK R ++  I+
Sbjct:  119 FNPSAGWLTRFKQRHSIREIN 139
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|B2RRL2|JERKL_MOUSE (Jerky protein homolog-like OS=Mus musculus OX=10090 GN=Jrkl PE=2 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 7.583e-18
Identity = 45/174 (25.86%), Postives = 81/174 (46.55%), Query Frame = 3 
Query: 1167 AKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSW 1688
             ++R+T++   N TG  ++K  ++  +  PR+ K     +L V + + + +WM   ++      + F+      LR K + +KA+L+LDN+P HP           +   + P N  S++QP+ QGVIA  K  Y         +E +      K FWK   +++    I  +W
Sbjct:  205 GEERITVMCCTNATGLHKLKLCVVGKARKPRSFKSTDTLNLPVSYFSQKGAWMDLSIFR-QWFDKIFVPQVREYLRSKGLQEKAVLLLDNSPTHPNENVLRSDDGQIFAKYLPPNVASLIQPLGQGVIAAMKRNYRAGLLHNNLEEGN----DLKSFWKKLTLLDALYEIAMAW 373

HSP 2 Score: 33.4982 bits (75), Expect = 7.583e-18
Identity = 24/112 (21.43%), Postives = 56/112 (50.00%), Query Frame = 3 
Query:  552 NGKQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNL------YNKFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGL 869
            +GK+ R  L ++ K+++I+++E G    + +   G+  +T+  I KN + +       +   +  +  + K S  E+++K +  W + Q  +  P+S  I  ++A+  +  L
Sbjct:    2 SGKRKRVVLTIKDKLDIIKKLEDGGSSKQLAVIYGIGETTVRDIRKNKEKIITYASSSDSTSLLAKRKSMKPSMYEELDKAMLEWFNQQRAKGNPISGPICAKRAEFFFYAL 113

HSP 3 Score: 30.0314 bits (66), Expect = 7.583e-18
Identity = 19/63 (30.16%), Postives = 31/63 (49.21%), Query Frame = 1 
Query:  976 ESASADKESSKVFEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFN 1164
            E  + D+ + + F  +  D  +Q N     I+N DET    FWK +PS+  + K + +  G N
Sbjct:  143 ERLNGDETAVEDFCNNFRDFIEQENLQPEQIYNADETG--LFWKCLPSRTTVIKGKCTVPGHN 203

HSP 4 Score: 20.7866 bits (42), Expect = 7.583e-18
Identity = 8/21 (38.10%), Postives = 12/21 (57.14%), Query Frame = 2 
Query:  905 FVPR*GWFEKFKLRANLHSIS 967
            F P  GW  +FK R ++  I+
Sbjct:  119 FNPSAGWLTRFKQRHSIREIN 139
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4W5G0|TIGD2_HUMAN (Tigger transposable element-derived protein 2 OS=Homo sapiens OX=9606 GN=TIGD2 PE=3 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 1.082e-13
Identity = 90/407 (22.11%), Postives = 178/407 (43.73%), Query Frame = 3 
Query:  555 GKQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYN------KFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILY--LGLKNRTEECSTADSLFQDEAGL-----KSLNYVQTYTALVVPGICQC**RIFKGI*EEFV*Y*KTIKLSSASYF*F**NLLMRFLEENAIKNIHLQRRKICFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLF 1736
            GK+ R  L ++ K+++I+++E G    + S   G+  ST+  I KN + + N            +  + K S  E++++++  W + Q    +P+S  I  ++AK  +  LG++      S   + F+   G+     K        TA           R F G  +EFV   +   L     +    +    F +    + + L+  +      S+++R+ ++   N TG  ++   ++  ++ PRA KG    +L V + + + +W+   ++      + F+      L+ K + +KA+L+LD  P  P           + + + P N TS++QPM QGV+AT K YY     ++   E +  +     FWKN  +++    +  +W  V+ + +    + LF
Sbjct:    3 GKRKRVVLTIKDKLDIIKKLEEGISFKKLSVVYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAA----------REFCGSFQEFV---EKENLQPEQIYGA--DQTGLFWKCLPSRTLTLETDQSTSGCRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQKGAWIEQSVFR-QWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYYRAGLLQKYMDEGNDPKI----FWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLF 389
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6NT04|TIGD7_HUMAN (Tigger transposable element-derived protein 7 OS=Homo sapiens OX=9606 GN=TIGD7 PE=1 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 2.539e-13
Identity = 63/219 (28.77%), Postives = 105/219 (47.95%), Query Frame = 3 
Query: 1119 KNIHLQRRKICFRF*S-AKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILY----I*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQ---LFQEVDSNQCSNKEFWKNFNIVNVKENI---GSSWLEVQQNCLKGCLEYLFIK 1742
            +N    R+ IC       K+RL+  +  N  G  ++K ++I  S+ P+++K  +  +L VI+  ++  W T  L+        V     +  N+ LR      +ALL+LD+ P HP + S       ++ +F P NT++++QPM+QGVI + K  Y  K  ++   +F+E D  Q    +      I N+K  I     SW EV+Q  +    E L  K
Sbjct:  189 ENSQASRKDICLPGKKINKERLSAFLCANADGTHKLKSIIIGKSKLPKSVKEDT-STLPVIYKPSKDVWFTRELFSEWFFQNFVPEVRHFQLNV-LRFHDEDVRALLLLDSCPAHPSSESLTSEDGRIKCMFFPHNTSTLIQPMNQGVILSCKRLYRWKQLEESLVIFEESDDEQEKGDKGVSKIKIYNIKSAIFNWAKSWEEVKQITIANAWENLLYK 405
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: A0A0D9R2B9 (Tigger transposable element derived 1 OS=Chlorocebus sabaeus OX=60711 GN=TIGD1 PE=4 SV=1)

HSP 1 Score: 172.94 bits (437), Expect = 5.537e-65
Identity = 91/205 (44.39%), Postives = 128/205 (62.44%), Query Frame = 3 
Query: 1158 F*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVD------SNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIED 1754
            F ++KDRLTLL+G N  GDF++KP+L+YHSENPRA+K  +K +L V++  N K+ MT+ L+  V  +  F         +K+I  K LL++DNAP HP+ + E      + ++F P NTTSILQPMDQGVI+TFK+YY+R TF +    +D      S Q   K FWK F I++  +NI  SW EV+ + L G  + L    I+D
Sbjct:  212 FKASKDRLTLLLGANAAGDFKLKPMLVYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFT-VWFTEYFKPTVETYCSEKKIPFKILLLIDNAPSHPRALMEIYK--EINVVFMPANTTSILQPMDQGVISTFKSYYLRNTFHKALAAMDRDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKMSTLAGVWKKLIPTLIDD 413

HSP 2 Score: 53.1434 bits (126), Expect = 5.537e-65
Identity = 29/66 (43.94%), Postives = 40/66 (60.61%), Query Frame = 1 
Query:  976 ESASADKESSKVFEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFNPRK 1173
            E+AS D E++  + ++L  I  +  Y +  IFN DET     WKKMPS+ FI++EEKS  GF   K
Sbjct:  153 EAASVDVEAAASYPEALAKIIDEGGYTKQQIFNVDETAF--CWKKMPSRTFIAREEKSVPGFKASK 216

HSP 3 Score: 52.7582 bits (125), Expect = 5.537e-65
Identity = 37/109 (33.94%), Postives = 58/109 (53.21%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFIICQENNT----QKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLK 872
            ++SR SL L  K+ +I+  E G  ++E   RLGL   T+  ++   +    +       NT    ++ S +  MEK+L  WI+DQT  N+PLSQ +I  KA  L+  +K
Sbjct:    9 RKSRTSLTLNQKLEMIKLSEEGMSKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKSATPMNTRMIRKRNSLIADMEKVLVVWIEDQTSHNIPLSQSLIQNKALTLFNSMK 117

HSP 4 Score: 36.1946 bits (82), Expect = 5.537e-65
Identity = 29/107 (27.10%), Postives = 53/107 (49.53%), Query Frame = 2 
Query: 1847 LIESDDHGIYNEDLFASLSQI*PEIADNTLETEDITEII-LTKKCLEYNLRIIQNSLEDLSENDPNFERSCAIKLGVMNTLSPYTEILKE-KNKTI*ARNLRQVFKK 2161
            L++S D  + +++L    +Q    +   +   ED   I+ +T K LEY + ++  +       D NFERS  +   + N+++ Y EI  E K++ +   +L   FKK
Sbjct:  448 LLQSHDKTVTDKELLLMDTQRKWFLEMESTPGEDAVNIVEMTTKDLEYYINLVDKAAAGFERIDSNFERSSTVGKMLSNSIACYREIFHERKSQLMRQTSLMSYFKK 554

HSP 5 Score: 27.7202 bits (60), Expect = 5.537e-65
Identity = 9/19 (47.37%), Postives = 12/19 (63.16%), Query Frame = 2 
Query:  920 GWFEKFKLRANLHSISRSG 976
            GWF +FK R+  H+I   G
Sbjct:  134 GWFMRFKERSRFHNIKAKG 152
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: H2RG68 (TIGD1 isoform 1 OS=Pan troglodytes OX=9598 GN=TIGD1 PE=4 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 2.277e-64
Identity = 92/205 (44.88%), Postives = 128/205 (62.44%), Query Frame = 3 
Query: 1158 F*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSN------QCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIED 1754
            F ++KDRLTLL+G N  GDF++KP+LIYHSENPRA+K  +K +L V++  N K+ MT+ L+     +  F         +K+I  K LLI+DNAP HP+ + E      + ++F P NTTSILQPMDQGVI+TFK+YY+R TF +    +DS+      Q   K FWK F I++  +NI  SW EV+ + L G  + L    I+D
Sbjct:  212 FKASKDRLTLLLGANAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFT-AWFTDYFKPTVETYCSEKKIPFKILLIIDNAPSHPRALMEIYE--EINVVFMPANTTSILQPMDQGVISTFKSYYLRNTFHKALAAMDSDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKLSTLTGVWKKLIPTLIDD 413

HSP 2 Score: 54.6842 bits (130), Expect = 2.277e-64
Identity = 38/109 (34.86%), Postives = 59/109 (54.13%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFIICQENNT----QKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLK 872
            ++SR SL L  K+ +I+  E G  ++E   RLGL   T+  ++   +    +       NT    ++ S +  MEK+L  WI+DQT RN+PLSQ +I  KA  L+  +K
Sbjct:    9 RKSRTSLTLNQKLEMIKLSEEGMSKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKSATPMNTRMIRKRNSLIADMEKVLVVWIEDQTSRNIPLSQSLIQNKALTLFNSMK 117

HSP 3 Score: 45.8246 bits (107), Expect = 2.277e-64
Identity = 24/54 (44.44%), Postives = 33/54 (61.11%), Query Frame = 1 
Query: 1012 FEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFNPRK 1173
            + ++L  I  +  Y +  IFN DET    +WKKMPS+ FI++EEKS  GF   K
Sbjct:  165 YPEALAKIIDEGGYTKQQIFNVDETAF--YWKKMPSRTFIAREEKSVPGFKASK 216

HSP 4 Score: 39.6614 bits (91), Expect = 2.277e-64
Identity = 30/107 (28.04%), Postives = 54/107 (50.47%), Query Frame = 2 
Query: 1847 LIESDDHGIYNEDLFASLSQI*PEIADNTLETEDITEII-LTKKCLEYNLRIIQNSLEDLSENDPNFERSCAIKLGVMNTLSPYTEILKE-KNKTI*ARNLRQVFKK 2161
            L++S D  + +E+LF   +Q    +   +   ED   I+ +T K LEY + ++  +       D NFERS  +   + N+++ Y EI  E K++ +   +L   F+K
Sbjct:  447 LLQSHDKTLTDEELFLMDAQRKWFLEMESTPGEDAVNIVEMTTKDLEYYINLVDKAAAGFERIDSNFERSSTVGKMLSNSIACYREIFHERKSQLMRKASLMSYFRK 553

HSP 5 Score: 28.4906 bits (62), Expect = 2.277e-64
Identity = 9/19 (47.37%), Postives = 13/19 (68.42%), Query Frame = 2 
Query:  920 GWFEKFKLRANLHSISRSG 976
            GWF +FK R++ H+I   G
Sbjct:  134 GWFMRFKERSHFHNIKAQG 152
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: G1S9M7 (Tigger transposable element derived 1 OS=Nomascus leucogenys OX=61853 GN=TIGD1 PE=4 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 2.411e-64
Identity = 91/205 (44.39%), Postives = 128/205 (62.44%), Query Frame = 3 
Query: 1158 F*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSN------QCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIED 1754
            F ++KDRLTLL+G N  GDF++KP+LIYHSENPRA+K  +K +L V++  N K+ MT+ L+     +  F         +K+I  K LL++DNAP HP+ + E      + ++F P NTTSILQPMDQGVI+TFK+YY+R TF +    +DS+      Q   K FWK F I++  +NI  SW EV+ + L G  + L    I+D
Sbjct:  212 FKASKDRLTLLLGANAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFT-AWFTEYFKPTVETYCSEKKIPFKILLLIDNAPSHPRALMEMYK--EINVVFMPANTTSILQPMDQGVISTFKSYYLRNTFHKALAAMDSDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKMSTLTGVWKKLIPTLIDD 413

HSP 2 Score: 54.6842 bits (130), Expect = 2.411e-64
Identity = 38/109 (34.86%), Postives = 59/109 (54.13%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFIICQENNT----QKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLK 872
            ++SR SL L  K+ +I+  E G  ++E   RLGL   T+  ++   +    +       NT    ++ S +  MEK+L  WI+DQT RN+PLSQ +I  KA  L+  +K
Sbjct:    9 RKSRTSLTLNQKLEMIKLSEEGMSKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKSATPMNTRMIRKRNSLIADMEKVLVVWIEDQTSRNIPLSQSLIQNKALTLFNSMK 117

HSP 3 Score: 46.2098 bits (108), Expect = 2.411e-64
Identity = 24/54 (44.44%), Postives = 33/54 (61.11%), Query Frame = 1 
Query: 1012 FEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFNPRK 1173
            + ++L  I  +  Y +  IFN DET    +WKKMPS+ FI++EEKS  GF   K
Sbjct:  165 YPEALAKIVDEGGYTKQQIFNVDETAF--YWKKMPSRTFIAREEKSVPGFKASK 216

HSP 4 Score: 39.6614 bits (91), Expect = 2.411e-64
Identity = 30/107 (28.04%), Postives = 54/107 (50.47%), Query Frame = 2 
Query: 1847 LIESDDHGIYNEDLFASLSQI*PEIADNTLETEDITEII-LTKKCLEYNLRIIQNSLEDLSENDPNFERSCAIKLGVMNTLSPYTEILKE-KNKTI*ARNLRQVFKK 2161
            L++S D  + +E+LF   +Q    +   +   ED   I+ +T K LEY + ++  +       D NFERS  +   + N+++ Y EI  E K++ +   +L   F+K
Sbjct:  447 LLQSHDKTLTDEELFLMEAQRKWFLEMESTPGEDAMNIVEMTTKDLEYYINLVDKAAAGFERIDSNFERSSTVGKMLSNSIACYREIFHERKSQLMRQTSLMSYFRK 553

HSP 5 Score: 27.7202 bits (60), Expect = 2.411e-64
Identity = 9/19 (47.37%), Postives = 12/19 (63.16%), Query Frame = 2 
Query:  920 GWFEKFKLRANLHSISRSG 976
            GWF +FK R+  H+I   G
Sbjct:  134 GWFMRFKERSRFHNIKAQG 152
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: A0A2J8TQ64 (TIGD1 isoform 1 OS=Pongo abelii OX=9601 GN=CR201_G0033185 PE=4 SV=1)

HSP 1 Score: 169.859 bits (429), Expect = 5.891e-64
Identity = 90/205 (43.90%), Postives = 127/205 (61.95%), Query Frame = 3 
Query: 1158 F*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSN------QCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIED 1754
            F ++KDRLTLL+G N  GDF++KP+LIYHSENPRA+K  +K +L V++  N K+ MT+ L+     +  F         +K+I  K LL++DNAP HP+ + E      + ++F P NTTSILQPMDQGVI+TFK+YY+R TF +    +DS+          K FWK F I++  +NI  SW EV+ + L G  + L    I+D
Sbjct:  212 FKASKDRLTLLLGANAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKAQMTAHLFT-AWFTEYFKPTVETYCSEKKIPFKILLLIDNAPSHPRALMEIYK--EINVVFMPANTTSILQPMDQGVISTFKSYYLRNTFHKALAAMDSDISDGSGHSKLKTFWKGFTILDAIKNIRESWEEVKLSTLTGVWKKLIPTLIDD 413

HSP 2 Score: 54.6842 bits (130), Expect = 5.891e-64
Identity = 38/109 (34.86%), Postives = 59/109 (54.13%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFIICQENNT----QKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLK 872
            ++SR SL L  K+ +I+  E G  ++E   RLGL   T+  ++   +    +       NT    ++ S +  MEK+L  WI+DQT RN+PLSQ +I  KA  L+  +K
Sbjct:    9 RKSRTSLTLNQKLEMIKLSEEGMSKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKSATPMNTRMIRKRNSLIADMEKVLVVWIEDQTSRNIPLSQSLIQNKALTLFNSMK 117

HSP 3 Score: 45.8246 bits (107), Expect = 5.891e-64
Identity = 24/54 (44.44%), Postives = 33/54 (61.11%), Query Frame = 1 
Query: 1012 FEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFNPRK 1173
            + ++L  I  +  Y +  IFN DET    +WKKMPS+ FI++EEKS  GF   K
Sbjct:  165 YPEALAKIIDEGGYTKQQIFNVDETAF--YWKKMPSRTFIAREEKSVPGFKASK 216

HSP 4 Score: 40.0466 bits (92), Expect = 5.891e-64
Identity = 26/91 (28.57%), Postives = 47/91 (51.65%), Query Frame = 2 
Query: 1847 LIESDDHGIYNEDLFASLSQI*PEIADNTLETEDITEII-LTKKCLEYNLRIIQNSLEDLSENDPNFERSCAIKLGVMNTLSPYTEILKEK 2116
            L++S D  + +E+LF   +Q    +   +   ED  +I+ +T K LEY + ++  +       D NFERS  +   + N+++ Y EI  E+
Sbjct:  447 LLQSHDKTLTDEELFLMDAQRKWFLEMESTPGEDAVKIVEMTTKDLEYYINLVDKAAAGFERIDSNFERSSTVGKMLSNSIACYREIFHER 537

HSP 5 Score: 28.8758 bits (63), Expect = 5.891e-64
Identity = 9/19 (47.37%), Postives = 13/19 (68.42%), Query Frame = 2 
Query:  920 GWFEKFKLRANLHSISRSG 976
            GWF +FK R++ H+I   G
Sbjct:  134 GWFMRFKERSHFHNIKAQG 152
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: G3RUC2 (Tigger transposable element derived 1 OS=Gorilla gorilla gorilla OX=9595 PE=4 SV=2)

HSP 1 Score: 169.859 bits (429), Expect = 1.555e-63
Identity = 90/205 (43.90%), Postives = 128/205 (62.44%), Query Frame = 3 
Query: 1158 F*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSN------QCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIED 1754
            F ++KDRLTLL+G N  GDF++KP+LIYHSENPRA+K  +K +L V++  N K+ MT+ L+     +  F         +K+I  K LL++DNAP HP+ + E      + ++F P NTTSILQPMDQGVI+TFK++Y+R TF +    +DS+      Q   K FWK F I++  +NI  SW EV+ + L G  + L    I+D
Sbjct:  212 FKASKDRLTLLLGANAAGDFKLKPMLIYHSENPRALKNYTKSTLPVLYKWNSKARMTAHLFT-AWFTEYFKPTVETYCSEKKIPFKILLLIDNAPSHPRALMEIYE--EINVVFMPANTTSILQPMDQGVISTFKSHYLRNTFHKALAAMDSDVSDGSGQSKLKTFWKGFTILDAIKNIRDSWEEVKLSTLTGVWKKLIPTLIDD 413

HSP 2 Score: 55.0694 bits (131), Expect = 1.555e-63
Identity = 38/109 (34.86%), Postives = 59/109 (54.13%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFIICQENNT----QKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLK 872
            ++SR SL L  K+ +I+  E G  ++E   RLGL   T+  ++   +    +       NT    ++ S +  MEK+L  WI+DQT RN+PLSQ +I  KA  L+  +K
Sbjct:    9 RKSRTSLTLNQKLEMIKLSEEGMSKAEIGRRLGLLRQTVSQVVNAKEKFLKEVKSATPMNTRMIRKRNSLIADMEKVLVVWIEDQTSRNIPLSQSLIQNKALTLFNSMK 117

HSP 3 Score: 45.8246 bits (107), Expect = 1.555e-63
Identity = 24/54 (44.44%), Postives = 33/54 (61.11%), Query Frame = 1 
Query: 1012 FEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFNPRK 1173
            + ++L  I  +  Y +  IFN DET    +WKKMPS+ FI++EEKS  GF   K
Sbjct:  165 YPEALAKIIDEGGYTKQQIFNVDETAF--YWKKMPSRTFIAREEKSVPGFKASK 216

HSP 4 Score: 39.6614 bits (91), Expect = 1.555e-63
Identity = 30/107 (28.04%), Postives = 54/107 (50.47%), Query Frame = 2 
Query: 1847 LIESDDHGIYNEDLFASLSQI*PEIADNTLETEDITEII-LTKKCLEYNLRIIQNSLEDLSENDPNFERSCAIKLGVMNTLSPYTEILKE-KNKTI*ARNLRQVFKK 2161
            L++S D  + +E+LF   +Q    +   +   ED   I+ +T K LEY + ++  +       D NFERS  +   + N+++ Y EI  E K++ +   +L   F+K
Sbjct:  447 LLQSHDKTLTDEELFLMDAQRKWFLEMESTPGEDAVNIVEMTTKDLEYYINLVDKAAAGFERIDSNFERSSTVGKMLSNSIACYREIFHERKSQLMRKASLMSYFRK 553

HSP 5 Score: 27.7202 bits (60), Expect = 1.555e-63
Identity = 9/19 (47.37%), Postives = 13/19 (68.42%), Query Frame = 2 
Query:  920 GWFEKFKLRANLHSISRSG 976
            GWF +FK R++ H+I   G
Sbjct:  134 GWFMRFKERSHFHNIKVQG 152
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003283.1 (pep scaffold:Pmarinus_7.0:GL479064:1419:3178:1 gene:ENSPMAG00000003000.1 transcript:ENSPMAT00000003283.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 147.132 bits (370), Expect = 5.317e-37
Identity = 71/194 (36.60%), Postives = 114/194 (58.76%), Query Frame = 3 
Query: 1164 SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILY----I*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYL 1733
            +AKDRLT+++G N +G +R+KP++++HS NPR +KG  +  L V + ++++ WMT  ++    +  +      YC     ++K    K LL++DNAP HP  + +      ++++F P +TTS+LQPM QGVIA FKAYY+R+TF  L +  D         W++FNI    + I  +W ++ Q CL G    L
Sbjct:  185 AAKDRLTVMLGANASGGYRLKPVVVHHSANPRTLKGFVRADLGVHFRSSKRGWMTDQMFTDYVLETLQDELRRYC-----KRKNQDFKILLVVDNAPSHPPYIVDLSEQ--IKVVFLPPHTTSLLQPMGQGVIAAFKAYYLRRTFAMLIEATDGENSQASVTWRSFNIKQAIDIIVEAWTDITQPCLNGVCRKL 371
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005656.1 (pep scaffold:Pmarinus_7.0:GL476578:539135:542172:1 gene:ENSPMAG00000005132.1 transcript:ENSPMAT00000005656.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 146.362 bits (368), Expect = 6.284e-37
Identity = 119/400 (29.75%), Postives = 180/400 (45.00%), Query Frame = 3 
Query:  564 SRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKF----IICQENNTQKKSQL-EKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLKNRTEECSTADSL---------FQDEAGLKSLNYVQTYTALVVPGICQC**RIFKGI*EEFV*Y*KTIKLSSASYF*F**NLLMRFLEENAIKNIHLQRRKICFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGC 1721
            S   L + MK  +IRR E GE   + S  LGLA ST+  I K ++N+  +      +     T+K+S L E ME+ L  WI  Q +  MPLS  +I  KA  L+   K R  E +  ++          F+    L+ L          V          FK   +E +   +    S    F    N    F +         +  K    F ++KDRL LL+G N  GD ++KPLL+YHS+ PRA+KG  K  L VIW +N+K W+T+ +++   +   F        +KK +  KALL+L+NAPGHP  +SE                                + ++R T +Q+    D +  + +EFW+++NI++  +NI  +W EV Q  L  C
Sbjct:   11 SLDELTINMKKYIIRRYEGGETVRDISKSLGLATSTVCGIHKASENIKARAQRMTPLVAAKLTRKRSPLMENMEESLGMWIKHQNEHRMPLSTALIQAKALRLFNDFKKRAGESAANETFGASTGWYAKFKGRYNLRHLKMTGETAGADVEAA-----EAFKSTLKEII---EGGGYSPEQVFNV--NETGLFWKRMPASTFLSREEKTAPGFKASKDRLALLVGANAAGDCKLKPLLVYHSKTPRALKGCIKADLPVIWRSNKKGWITASVFL-DWLKNHFCPAIEKYCKKKNLDHKALLLLNNAPGHPPTLSEL-------------------------------SEHVRGTMEQIVANTDKDVQTIREFWRSYNIMDAIDNINEAWNEVAQTTLNAC 368

HSP 2 Score: 60.077 bits (144), Expect = 4.196e-10
Identity = 46/154 (29.87%), Postives = 74/154 (48.05%), Query Frame = 1 
Query:  976 ESASADKESSKVFEKSLYDIKKQ*NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFNPRKIG*PY**VEIKLVIS--G*NHC*FIIL-----KIPGP*KGFLNNHYLSFG*QTENHG*HQFYIYK*WYQEHFCTAVISYCERKGLEKK 1416
            E+A AD E+++ F+ +L +I +   Y    +FN +ET    FWK+MP+  F+S+EEK+A GF   K         + L++       C    L     K P   KG +    L    ++   G     ++  W + HFC A+  YC++K L+ K
Sbjct:  154 ETAGADVEAAEAFKSTLKEIIEGGGYSPEQVFNVNETG--LFWKRMPASTFLSREEKTAPGFKASKD-------RLALLVGANAAGDCKLKPLLVYHSKTPRALKGCIKAD-LPVIWRSNKKGWITASVFLDWLKNHFCPAIEKYCKKKNLDHK 297

HSP 3 Score: 23.0978 bits (48), Expect = 4.196e-10
Identity = 9/19 (47.37%), Postives = 12/19 (63.16%), Query Frame = 2 
Query:  920 GWFEKFKLRANLHSISRSG 976
            GW+ KFK R NL  +  +G
Sbjct:  135 GWYAKFKGRYNLRHLKMTG 153
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004972.1 (pep scaffold:Pmarinus_7.0:GL476545:74372:75575:-1 gene:ENSPMAG00000004517.1 transcript:ENSPMAT00000004972.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 130.183 bits (326), Expect = 1.113e-32
Identity = 76/187 (40.64%), Postives = 109/187 (58.29%), Query Frame = 3 
Query: 1158 F*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKG 1718
            F + KDRLTLL+GGN    +++KP +IYHS N RA+  ISK  L V +  N+K+WMT++L+    V+  F+       RK  I  K +LILDNAPGH Q + +     P  ++F P NTTSI+QPMDQG +AT +          L ++  + +   +  WK  N++N   NIG +W EV + C+ G
Sbjct:  181 FKAFKDRLTLLLGGN-VAVYKLKPFMIYHSTNARALARISKNMLPVHYRHNKKAWMTAVLFEDWFVN-CFIPEVKEHCRKNGIPFKIMLILDNAPGHLQYIGDND---PNVVVFLPPNTTSIIQPMDQGAVATSQGL--------LSEKHATEEKELRMIWKESNVLNAIRNIGRAWKEVTKECMNG 354

HSP 2 Score: 60.4622 bits (145), Expect = 1.481e-9
Identity = 38/112 (33.93%), Postives = 64/112 (57.14%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLKNRTEECS 893
            K+ RK++ LE KM +I + E+G+  +  +    L+ STI  I+K+   +     I     T+    LE+ME+LL  W++D+ Q+ MPLS   I  KA++L+  LK R ++ +
Sbjct:    3 KKKRKAITLEQKMKIINQHEAGKAVTVIARDNQLSQSTISAIVKDKKRIMEASTIISRKRTE---PLEEMEQLLVTWMEDRIQKRMPLSLLTIQAKARMLFYDLKKRYDDAT 111
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005921.1 (pep scaffold:Pmarinus_7.0:GL487978:976:2666:1 gene:ENSPMAG00000005352.1 transcript:ENSPMAT00000005921.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 124.405 bits (311), Expect = 5.479e-30
Identity = 64/167 (38.32%), Postives = 95/167 (56.89%), Query Frame = 3 
Query: 1248 ENPRAIKGISKQSLLVIWMTNRKSWMTSILY----I*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSN-KEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYL 1733
            ENPRA KGISK +L V +  N  +W+T  ++    I   +     YC     R + I  K LL++DNAP HP ++ +F     ++++F P N TS+LQPMDQGV A  KAYY+R+T  Q  +  + +     +EFW+ +++    +NI  +W EV Q CL G  E +
Sbjct:  189 ENPRAFKGISKATLPVYFRANPTAWVTVAIFEDWFINCFIPDVEKYC-----RDEGIPFKILLVIDNAPSHPAHLDDFHPN--IKVVFLPPNATSVLQPMDQGVNAKCKAYYLRRTLAQALEATEGDTGKTVREFWEAYDVYQAVQNIAKAWAEVTQTCLNGAWEKM 348

HSP 2 Score: 47.7506 bits (112), Expect = 2.238e-6
Identity = 40/142 (28.17%), Postives = 66/142 (46.48%), Query Frame = 3 
Query:  516 MAERRTGELQAHNGKQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNTDNLYNKF-----IICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLKNRTEECSTADSLFQDEAG 926
            M+ +R  + +     + RK + L  KM +I + E G+  S  S  LGLA ST+ TILK+   +         +       Q+   + +ME+LLT W++      +PLS   I  KA+ ++  +K +      AD+ F    G
Sbjct:    1 MSGKRPSDREITGSARKRKVIDLGQKMEIINKHERGQTLSSISRELGLATSTVNTILKDGARIKEHVKGLAPLTSTVITKQRSGAIYEMEQLLTLWMEANVDGRVPLSLVAIQAKARSIFEDVKGK---YGDADATFAASHG 139

HSP 3 Score: 22.7126 bits (47), Expect = 2.238e-6
Identity = 8/24 (33.33%), Postives = 12/24 (50.00%), Query Frame = 2 
Query:  905 FVPR*GWFEKFKLRANLHSISRSG 976
            F    GWF +FK R+    ++  G
Sbjct:  134 FAASHGWFNRFKARSRFRDVTVRG 157
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003106.1 (pep scaffold:Pmarinus_7.0:GL476998:37517:41189:1 gene:ENSPMAG00000002845.1 transcript:ENSPMAT00000003106.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.176 bits (313), Expect = 5.547e-30
Identity = 67/164 (40.85%), Postives = 99/164 (60.37%), Query Frame = 3 
Query: 1245 SENPRAIKGISKQSLLVIWMTNRKSWMTSILY----I*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSN-KEFWKNFNIVNVKENIGSSWLEVQQNCLKGC 1721
            +ENPRA+KG +K +L VIW +N K+ +T  ++        V     YC     R   +  KA+L+LDNAP HP +V  F     ++++F   NTT++LQPMDQGV+++FKAYY+R+TF Q     D        EFWK F+I++  +NI +SW E++Q+ L G 
Sbjct:  181 TENPRALKGYTKNTLPVIWKSNPKARVTGAIFEEWFRVYFVPAVKEYC-----RTNNLAFKAILVLDNAPCHPVSVEGFDPN--IKVVFLTPNTTALLQPMDQGVMSSFKAYYLRQTFAQAISATDKEGGPTLTEFWKGFSILDAVKNIAASWKEMKQSNLNGV 337

HSP 2 Score: 62.3882 bits (150), Expect = 2.527e-11
Identity = 44/127 (34.65%), Postives = 75/127 (59.06%), Query Frame = 3 
Query:  558 KQSRKSLALEMKMNVIXXXXXXXXXXXXXXXLGLAGSTIITILKNT----DNLYNKFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNMPLSQGIIMEKAKILYLGLKNRTEECSTADSLFQDEAG 926
            K+SRKS+ LE+K  +I+  ++GE  +E + +L L  +T++TILK+     + +  +  +      Q+   + +MEK L  W+DDQT+ ++P+S  II  KA+ L+  LK R  E S +++ FQ   G
Sbjct:    9 KRSRKSVTLEIKYKIIKLADNGESNTEIARKLELPRTTVVTILKDKARILEEVKGQAPMQAAYIRQRAGLIAEMEKHLIVWLDDQTRHHVPVSLAIIQAKARSLFEHLKARRGEGSQSET-FQASKG 134

HSP 3 Score: 24.6386 bits (52), Expect = 2.527e-11
Identity = 8/19 (42.11%), Postives = 10/19 (52.63%), Query Frame = 2 
Query:  920 GWFEKFKLRANLHSISRSG 976
            GWF +FK R   H +   G
Sbjct:  134 GWFNRFKSRFKFHEMRVKG 152
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Nematostella
Match: EDO44738 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUQ6])

HSP 1 Score: 74.3294 bits (181), Expect = 8.363e-14
Identity = 55/190 (28.95%), Postives = 96/190 (50.53%), Query Frame = 3 
Query: 1164 SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKT-FKQLFQEVDSNQC-SNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLE 1727
            ++ +RLT+ +  N  G+F  KPL+I  + NP     +  + L VIW  NR++W+T+ ++        +L   +  +R+K   ++ LL LDN+P HP  + +      V +I    NT + LQP+ QG++  F+  Y RK  F  L +  DSN   S K+  +    ++    I ++  E+  + +  C E
Sbjct:  188 TSTERLTVTLCCNMDGEFE-KPLVIGPTANPPCFAKLDSECLPVIWRANRRAWITTSIFA------DWLRTLDRKMRQK--DRRILLFLDNSPPHPPTL-QLTNVKLVFLIKPSNNTVNQLQPLTQGIVEAFRMAYRRKVLFSTLAKLDDSNSPRSAKQLMQEITELDACFWIAATLDEISGSTMMNCFE 367
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000031980.1 (pep primary_assembly:ASM223467v1:3:6881985:6888319:-1 gene:ENSORLG00000025652.1 transcript:ENSORLT00000031980.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 137.887 bits (346), Expect = 1.205e-37
Identity = 81/200 (40.50%), Postives = 119/200 (59.50%), Query Frame = 3 
Query: 1158 F*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSN-KEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIED 1754
            F + KDRLTL+  GN  G F +KP LIY S+NPRA+K  +K  L V WM N K+WMT  L +       F+      LR K +  K LL++DNA GH  +++    C  V+I F P NTTS++QPMDQG+I  FKA Y R T + L   +DS+Q S+ K++W+ + I +  +NI  +  E++   L  C + L+ + +++
Sbjct:  140 FKAQKDRLTLVKCGNAAG-FMIKPGLIYRSKNPRALKNKNKDDLHVCWMYNAKAWMTKALNL-DWFKNCFIPQVKCYLRGKGLDFKVLLLVDNAGGHADDLA--YDC--VQIKFLPPNTTSLIQPMDQGIIRAFKALYTRNTLQHLVDAMDSDQDSSLKDYWRGYTIASCLQNIQRAIQEMKTETLNACWKKLWPEAVQN 333

HSP 2 Score: 40.817 bits (94), Expect = 1.205e-37
Identity = 21/42 (50.00%), Postives = 25/42 (59.52%), Query Frame = 1 
Query: 1048 NYPRHLIFNFDETF**DFWKKMPSKIFISKEEKSASGFNPRK 1173
             Y    IFN DET    FWK+MPS+ FI +EE  A GF  +K
Sbjct:  105 GYKPEQIFNIDETG--LFWKRMPSRTFIMQEEAKAPGFKAQK 144
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000036785.1 (pep primary_assembly:ASM223467v1:22:11796267:11802170:-1 gene:ENSORLG00000024024.1 transcript:ENSORLT00000036785.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 123.635 bits (309), Expect = 6.834e-29
Identity = 79/213 (37.09%), Postives = 119/213 (55.87%), Query Frame = 3 
Query: 1119 KNIHLQRRKICFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQ-CSNKEFWKNFNIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIED 1754
            K I  Q +   FR    KDR+TL++ GN  G F +KP LI   +NPRA+K  +  +L V WM N  +WMT  L +       F+      L +K +  K LL++DNA G   ++S       V+I F P NT+S++QPMDQG+I TFKA Y R T + L   +DS+Q  S K++W+ + I +  ++I  +  E++   L GC E L+ + + +
Sbjct:  168 KQIPSQAKASGFR--GQKDRVTLVMCGNAAG-FMIKPGLISRLKNPRALKNKNMSALPVYWMHNTMAWMTKALNL-NWFKGCFIPEVKGYLTEKGLDFKVLLLIDNAGGFADDLSHDG----VQIEFLPPNTSSLIQPMDQGIIRTFKALYTRNTLQHLVDAMDSDQNFSFKDYWREYTIASCLQHIQRAHQEMKSETLNGCWEKLWPEAVHN 372
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000029226.1 (SMESG000029226.1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.430e-15
Identity = 63/195 (32.31%), Postives = 96/195 (49.23%), Query Frame = 3 
Query: 1149 CFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQ----QNCLKGC 1721
            CF    +K+R+T+L G +  G  ++ PL+I  S  PR IK I+  +L   +++NRK+WMT  ++       +        L K R   K LL +DN  GH            V++ F   N TS LQPMD+G+IA FK  Y     +++ + ++ + C N E     N+  V + I S W ++     QNC K C
Sbjct: 2290 CFNGEKSKERITILFGCDAAGSDKLTPLVIGKSLKPRCIKLINMSNLGFYYLSNRKTWMTEGVF-----RESIAKIDKRFLAKNR---KILLFIDNFSGHALKSQSNN----VKVAFFHLNCTSKLQPMDKGIIANFKLKYRSAMVRRILENLEVD-CENIE---EINVKQVIDFIVSVWKDMNCSIIQNCFKKC 2468
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000029226.1 (SMESG000029226.1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.488e-15
Identity = 63/195 (32.31%), Postives = 96/195 (49.23%), Query Frame = 3 
Query: 1149 CFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQ----QNCLKGC 1721
            CF    +K+R+T+L G +  G  ++ PL+I  S  PR IK I+  +L   +++NRK+WMT  ++       +        L K R   K LL +DN  GH            V++ F   N TS LQPMD+G+IA FK  Y     +++ + ++ + C N E     N+  V + I S W ++     QNC K C
Sbjct: 2135 CFNGEKSKERITILFGCDAAGSDKLTPLVIGKSLKPRCIKLINMSNLGFYYLSNRKTWMTEGVF-----RESIAKIDKRFLAKNR---KILLFIDNFSGHALKSQSNN----VKVAFFHLNCTSKLQPMDKGIIANFKLKYRSAMVRRILENLEVD-CENIE---EINVKQVIDFIVSVWKDMNCSIIQNCFKKC 2313
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000029226.1 (SMESG000029226.1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.498e-15
Identity = 63/195 (32.31%), Postives = 96/195 (49.23%), Query Frame = 3 
Query: 1149 CFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQ----QNCLKGC 1721
            CF    +K+R+T+L G +  G  ++ PL+I  S  PR IK I+  +L   +++NRK+WMT  ++       +        L K R   K LL +DN  GH            V++ F   N TS LQPMD+G+IA FK  Y     +++ + ++ + C N E     N+  V + I S W ++     QNC K C
Sbjct: 2358 CFNGEKSKERITILFGCDAAGSDKLTPLVIGKSLKPRCIKLINMSNLGFYYLSNRKTWMTEGVF-----RESIAKIDKRFLAKNR---KILLFIDNFSGHALKSQSNN----VKVAFFHLNCTSKLQPMDKGIIANFKLKYRSAMVRRILENLEVD-CENIE---EINVKQVIDFIVSVWKDMNCSIIQNCFKKC 2536
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000029226.1 (SMESG000029226.1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.668e-15
Identity = 63/195 (32.31%), Postives = 96/195 (49.23%), Query Frame = 3 
Query: 1149 CFRF*SAKDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNFNIVNVKENIGSSWLEVQ----QNCLKGC 1721
            CF    +K+R+T+L G +  G  ++ PL+I  S  PR IK I+  +L   +++NRK+WMT  ++       +        L K R   K LL +DN  GH            V++ F   N TS LQPMD+G+IA FK  Y     +++ + ++ + C N E     N+  V + I S W ++     QNC K C
Sbjct: 2197 CFNGEKSKERITILFGCDAAGSDKLTPLVIGKSLKPRCIKLINMSNLGFYYLSNRKTWMTEGVF-----RESIAKIDKRFLAKNR---KILLFIDNFSGHALKSQSNN----VKVAFFHLNCTSKLQPMDKGIIANFKLKYRSAMVRRILENLEVD-CENIE---EINVKQVIDFIVSVWKDMNCSIIQNCFKKC 2375
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000000180.1 (SMESG000000180.1)

HSP 1 Score: 58.151 bits (139), Expect = 1.531e-9
Identity = 42/131 (32.06%), Postives = 66/131 (50.38%), Query Frame = 3 
Query: 1170 KDRLTLLIGGN*TGDFRMKPLLIYHSENPRAIKGISKQSLLVIWMTNRKSWMTSILYI*VMVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIFTPQNTTSILQPMDQGVIATFK 1562
            K R+TLL+  N +   +   L+I  S+  RA K      + V +  N  +WMT+ L+    + RA+    N      + G++ L+ LDN  GHPQ +        ++++F   NTT+  QPMDQG+I   K
Sbjct:   15 KQRITLLVEANMSDSEKFSRLVIDASKRSRAFKN---NEVPVEYKANSTAWMTAKLF--EEIFRAWDGRLN------QQGRRVLVCLDNFAGHPQELE----LNNIQLVFFQPNTTANSQPMDQGIIENLK 130
The following BLAST results are available for this feature:
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TIGD12.718e-6744.88tigger transposable element derived 1 [Source:HGNC... [more]
JRKL2.688e-1927.43JRK like [Source:HGNC Symbol;Acc:HGNC:6200][more]
TIGD22.253e-1422.11tigger transposable element derived 2 [Source:HGNC... [more]
TIGD22.253e-1422.11tigger transposable element derived 2 [Source:HGNC... [more]
TIGD75.286e-1428.77tigger transposable element derived 7 [Source:HGNC... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
kif67.167e-1323.74kinesin family member 6 [Source:Xenbase;Acc:XB-GEN... [more]
apmapl9.370e-1326.53adipocyte plasma membrane associated protein LIKE ... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Jrkl1.240e-1825.86Jrk-like [Source:MGI Symbol;Acc:MGI:1924782][more]
Tigd29.264e-1422.19tigger transposable element derived 2 [Source:MGI ... [more]
Jrk5.075e-1126.23jerky [Source:MGI Symbol;Acc:MGI:106214][more]
Tigd47.645e-1129.19tigger transposable element derived 4 [Source:MGI ... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q96MW7|TIGD1_HUMAN1.204e-6644.88Tigger transposable element-derived protein 1 OS=H... [more]
sp|Q9Y4A0|JERKL_HUMAN1.192e-1827.43Jerky protein homolog-like OS=Homo sapiens OX=9606... [more]
sp|B2RRL2|JERKL_MOUSE7.583e-1825.86Jerky protein homolog-like OS=Mus musculus OX=1009... [more]
sp|Q4W5G0|TIGD2_HUMAN1.082e-1322.11Tigger transposable element-derived protein 2 OS=H... [more]
sp|Q6NT04|TIGD7_HUMAN2.539e-1328.77Tigger transposable element-derived protein 7 OS=H... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0D9R2B95.537e-6544.39Tigger transposable element derived 1 OS=Chloroceb... [more]
H2RG682.277e-6444.88TIGD1 isoform 1 OS=Pan troglodytes OX=9598 GN=TIGD... [more]
G1S9M72.411e-6444.39Tigger transposable element derived 1 OS=Nomascus ... [more]
A0A2J8TQ645.891e-6443.90TIGD1 isoform 1 OS=Pongo abelii OX=9601 GN=CR201_G... [more]
G3RUC21.555e-6343.90Tigger transposable element derived 1 OS=Gorilla g... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000003283.15.317e-3736.60pep scaffold:Pmarinus_7.0:GL479064:1419:3178:1 gen... [more]
ENSPMAT00000005656.16.284e-3729.75pep scaffold:Pmarinus_7.0:GL476578:539135:542172:1... [more]
ENSPMAT00000004972.11.113e-3240.64pep scaffold:Pmarinus_7.0:GL476545:74372:75575:-1 ... [more]
ENSPMAT00000005921.15.479e-3038.32pep scaffold:Pmarinus_7.0:GL487978:976:2666:1 gene... [more]
ENSPMAT00000003106.15.547e-3040.85pep scaffold:Pmarinus_7.0:GL476998:37517:41189:1 g... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO447388.363e-1428.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSORLT00000031980.11.205e-3740.50pep primary_assembly:ASM223467v1:3:6881985:6888319... [more]
ENSORLT00000036785.16.834e-2937.09pep primary_assembly:ASM223467v1:22:11796267:11802... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000029226.11.430e-1532.31SMESG000029226.1[more]
SMESG000029226.11.488e-1532.31SMESG000029226.1[more]
SMESG000029226.11.498e-1532.31SMESG000029226.1[more]
SMESG000029226.11.668e-1532.31SMESG000029226.1[more]
SMESG000000180.11.531e-932.06SMESG000000180.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006150 ID=SMED30006150|Name=HTH CENPB-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4230bp
GTTAATTATAATATTTTAAATTTTAAAACATTTTTATATCTTTTCAATAA
ATTTTTGAAGTTCCATGAATAGAATCTTCAAAAAAATTATCAAAAATAAA
AAGTCAAATCAAGAAATATAGTTTGAATATAGAAATTATTACTCAAAATC
TAAATAATTGATTTTTAGATGTAAATTTGCACTATTTTACTTTAATACAG
GCATACTTCGGTTAATGCTAACTCTTTTAGCACTGTTTCGCTACAGCGCT
CTTTTTTTCGAAAAACAAATTATTTTAACTTTAAAATATTTTTAAAAAGG
CTTTCTTTTTCAAATTTCGCAGAAAAATTAATTTATAATTGTGGAAATCC
TTCATTTTGAAAAAAAAGTCAAAAATAACTTAATTCGGGGAATCCCATTT
GTGAAAATTTGCATTAAGTTGTTGATTCGAACTAATGATATGGTTTGATA
TAGCACCAGTAATTTTATTAAATAAATAAAATTGATGAATAAAAAAATCA
ATTGCTTATAAAAATATGGCTGAGAGAAGAACGGGTGAACTACAGGCCCA
CAATGGTAAACAAAGTAGAAAAAGCTTGGCGTTGGAGATGAAAATGAATG
TTATTAGGCGGATTGAGAGCGGTGAACGACAATCCGAAGAGTCCTCCAGG
CTGGGTTTGGCCGGATCAACTATTATAACCATTCTTAAAAATACCGATAA
TTTGTACAACAAATTCATTATCTGTCAAGAAAATAACACGCAAAAGAAAT
CTCAACTGGAAAAAATGGAGAAACTATTAACATTTTGGATTGATGATCAA
ACACAGAGAAACATGCCGCTCAGCCAGGGCATCATAATGGAAAAGGCTAA
GATATTATATCTGGGGCTTAAAAATCGAACTGAAGAATGCTCCACAGCCG
ATAGTTTGTTCCAAGATGAGGCTGGTTTGAAAAGTTTAAACTACGTGCAA
ACTTACACAGCATTAGTCGTTCCGGGAATCTGCCAGTGCTGATAAAGAAT
CTTCAAAGGTATTTGAGAAGAGTTTGTATGATATTAAAAAACAATAAAAT
TATCCTCGGCATCTTATTTTTAATTTTGATGAAACCTTTTGATGAGATTT
TTGGAAGAAAATGCCATCAAAAATATTCATCTCCAAAGAAGAAAAATCTG
CTTCAGGTTTTAATCCGCGAAAGATCGGTTAACCTTATTAATAGGTGGAA
ATTAAACTGGTGATTTCAGGATGAAACCACTGCTAATTTATCATTCTGAA
AATCCCAGGGCCATAAAAGGGATTTCTAAACAATCACTACTTGTCATTTG
GATGACAAACCGAAAATCATGGATGACATCAATTTTATATATATAAGTAA
TGGTATCAAGAGCATTTCTGTACTGCTGTAATATCATATTGCGAAAGAAA
AGGATTGGAAAAAAAGCATTGCTGATTCTCGACAATGCTCCTGGACACCC
TCAAAATGTATCAGAATTTCAAACTTGTTGGCCTGTAGAAATTATTTTTA
CACCTCAAAATACCACATCAATTTTGCAACCGATGGACCAAGGAGTTATT
GCAACTTTCAAGGCATATTATATTCGAAAAACCTTTAAGCAACTTTTTCA
AGAAGTTGACAGCAATCAATGTTCCAACAAAGAATTTTGGAAGAATTTTA
ATATCGTGAATGTCAAAGAAAATATCGGTTCATCATGGCTAGAAGTACAA
CAAAATTGTCTCAAAGGATGTTTGGAATACTTGTTTATTAAAACGATTGA
AGATAATTTATGAACTATCACAAGTTATTATTGAAATTTCGGAAATAGCA
AATTATATTGGATTTGCGGAGGTTGACGAGGGAAACATCCAAAAAACTAA
TTGAAAGTGATGACCATGGTATCTATAATGAGGATCTTTTTGCTAGTTTA
TCACAAATATAGCCAGAAATTGCGGACAATACGTTAGAAACGGAAGATAT
AACAGAAATTATTTTAACGAAAAAATGTTTGGAATATAATCTAAGGATAA
TCCAAAATTCCTTAGAAGATTTAAGTGAAAATGATCCGAATTTTGAAAGG
TCCTGCGCTATAAAACTAGGAGTAATGAACACTTTATCACCCTACACTGA
AATTTTAAAAGAAAAAAATAAAACTATTTAAGCAAGGAACCTTAGACAAG
TTTTTAAAAAATCATAATTTAAATATGAATTTAAACCTTTATTTTGTTAA
ATGTACCTTTATAGTTTTTTGTTTTTATTGGAATTATTTTTTTATATTGA
ATCCTACTTTATTTTCTAATTTTTAAATTAAGAAAAAATGAAGCAAAGAA
ATCATATTAAAATAAAATACCATCTTTTTTATTTTTGCCTTCAAAGTACC
AAAAAAAATTATTTAGGAACGTAACCCCATATTTTAATGTAAATAATACC
TCTTTTAACGCTGTTTCAGTTAAGGCTCAATTTTCAGGAACGCATTATGA
GCACTAAACGAGGTATGCCTGTACTAGAGTTTAATTTCATAAAGGCTCAA
AATATTTCTAATCAAAAATTTGAGGATCGTGGTGAACAGAAATCATGTAA
AAATAATTTTCCTTTTCCATGTGCAATTGATGTTACCGTAGCGATGTAAA
AATCTGTAAGAAGTAAAAGAAAGAATAAATCCTTTCATTTTTATTGTTTT
TAGTTTGTAAAATATCTAACATCATCACTAATACAAAGGGGAAATACGAT
TCTGAAGTTTTCTGAAAACATTTTCGAACTGATTTTCAGAGATTCCAGCA
GTCACATCTTGCAAATAAATACTAAATAAAATTTTTAATGACTAAAATCT
AGATACATTAAATTTTCTAATCCTATTTTTATAGATTTTTCTATTACATT
TACTAATAAAATAATAAGGACTTTGTGGACACCCAACATATAAGTTTGCA
TTTGGTTATTTGCACTTTTTTGTAATTATTTGAATTTTGTGTAAAATTTT
ATTGATTAAATCGTGTTTTCCGCTTTATTTTCCACATTAATTTATACATT
AATTTAGTTCTTAACACATTGTAATCGGATCACGTATTAATACGTGTTTA
GCAAATTAATGCTAGAGAGCGTATCACGTATTTATACGTTTTTGATAGAT
TGTTAGTGGAGCGCGGGTCACGTTAAAATGCGGGTTCCAATATTTTTGAA
GTTATCGCAATTTTTCTAGAGGTCTACGTTAGCGCGAAATTACGCGAAAA
ATCACCCGTTACCAGCACTAGTACGCGGCCGAAAACTGCCCGATCACAAT
GTGTTAAGTTTCAGTTTATTTTTAAACATTTTGACCAAAAGTAGTATTTT
CCAGATGCTGGACAGTCTAAACTATCAAAGTTATTGATCGGTTAATTTAT
TACAAAATGTTATATTAGTTTAATGTGCTATATGGTTGTAAATAATTCAA
CAAATATTGATATCCTAACTATGTCACTCCAATAAAACAATTACTGACAC
TCAATAACATTCAATTTTCAATTGACATTCTATTATACTCATCTACAGAT
GGATAAATATAAAAACAATATGATTTGCGCATTTAAACAATGAGCAAGTT
GAAACTGCTGATAATGTCATTGGTAAAAATTATTTACAAATTATTGTTTT
CTGATAATTTGCAATTTTCTTCATTAAAAATAATCTTATAAACGATCCAG
TGTCAAAGGTATGAAGGATAATGTTGAATTTTGATTTTTCCGGTTTCATT
GTTTTTGAATATGTAATGATTACTCAGTTTTTGAAGTTTAGTTAATGTTA
ATAGCAATTAAATATAATAATTAATTTGATGAGAATGATTTTATTAGCCC
ATGTAATGCGCAATTAACATGATGTTATTGGTCCATTATGTAGTGAAATA
TATTTCTACTATTGGTTACCTAACAATTAAAGTTTTATTTTAAATTCAAC
GTTAAAAAAGCGTGTTTAGATTTTCTTGAACTTCGAAATTTTAATATTTT
TCTTGATTTTATTTCATTATTTTTTTTACAGTATTCACCTGTGAACCAGG
CCAGACGTTGATACTAAACAAATACTTCAGCACTATTGTAAATGACTAAT
TAATTTATTACAATTAGCCTTCAGCATTATTTGTGGAAATGAAAACAGTT
GCAGTTTCATGGTTGATTGAATTTTTAATTAATAATAACTATTATTGATT
TTTGATTGTGTCAATTGAATTTTTGCCATTTTCATTTGTCGCTTATTATA
AATATAATTATTTGACACTTGAAAAAAAAA
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protein sequence of SMED30006150-orf-1

>SMED30006150-orf-1 ID=SMED30006150-orf-1|Name=SMED30006150-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=159bp
MAERRTGELQAHNGKQSRKSLALEMKMNVIRRIESGERQSEESSRLGLAG
STIITILKNTDNLYNKFIICQENNTQKKSQLEKMEKLLTFWIDDQTQRNM
PLSQGIIMEKAKILYLGLKNRTEECSTADSLFQDEAGLKSLNYVQTYTAL
VVPGICQC*
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protein sequence of SMED30006150-orf-2

>SMED30006150-orf-2 ID=SMED30006150-orf-2|Name=SMED30006150-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=138bp
MVSRAFLYCCNIILRKKRIGKKALLILDNAPGHPQNVSEFQTCWPVEIIF
TPQNTTSILQPMDQGVIATFKAYYIRKTFKQLFQEVDSNQCSNKEFWKNF
NIVNVKENIGSSWLEVQQNCLKGCLEYLFIKTIEDNL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000101muscle cell
PLANA:0002032epidermal cell
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR036388WH-like_DNA-bd_sf
IPR004875DDE_SF_endonuclease_dom
IPR007889HTH_Psq
IPR009057Homeobox-like_sf
IPR006600HTH_CenpB_DNA-bd_dom
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0003677DNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 12..79
e-value: 1.9E-7
score: 32.5
IPR007889DNA binding HTH domain, Psq-typePFAMPF04218CENP-B_Ncoord: 15..63
e-value: 7.5E-8
score: 31.9
NoneNo IPR availableGENE3DG3DSA:1.10.10.60coord: 80..129
e-value: 4.2E-5
score: 25.6
NoneNo IPR availablePANTHERPTHR19303:SF27coord: 6..130
NoneNo IPR availablePANTHERPTHR19303TRANSPOSONcoord: 6..130
IPR006600HTH CenpB-type DNA-binding domainPFAMPF03221HTH_Tnp_Tc5coord: 82..120
e-value: 1.1E-5
score: 25.3
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 76..119
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 16..67