Helicase with zinc finger domain 2

Overview
NameHelicase with zinc finger domain 2
Smed IDSMED30006144
Length (bp)5959
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Helicase with zinc finger domain 2 (SMED30006144) t-SNE clustered cells

Violin plots show distribution of expression levels for Helicase with zinc finger domain 2 (SMED30006144) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Helicase with zinc finger domain 2 (SMED30006144) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Helicase with zinc finger domain 2 (SMED30006144) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006144

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30006144h1SMcG0018707 Contig229GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30006144h1SMcG0018707 Contig229GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
epidermisSMED30006144h1SMcG0018707 dd_Smed_v4_7048_0_1dd_Smed_v4PMID:27063937
Scimone et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
nervous systemSMED30006144h1SMcG0018707 dd_Smed_v4_7048_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30006144h1SMcG0018707 dd_Smed_v4_7048_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006144h1SMcG0018707 dd_Smed_v4_7048_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30006144h1SMcG0018707 dd_Smed_v4_7048_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30006144h1SMcG0018707 dd_Smed_v4_7048_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30006144h1SMcG0018707 dd_Smed_v4_7048_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30006144h1SMcG0018707 dd_Smed_v4_7048_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Human
Match: HELZ2 (helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021])

HSP 1 Score: 345.125 bits (884), Expect = 4.827e-95
Identity = 351/1448 (24.24%), Postives = 615/1448 (42.47%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDD-----PANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYH-ISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDN-----RIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSC----PPY-LNSSSSNDNKFKIDSHLFDSYLPYSD-------SKLFQEIRRSYLSGEALENK-LNQL----CTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLR-SDIFHKEIYKIFNRYEYLIAS------GISSVGGDLLCLRCRKEDWNNY-WVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVN-----FTLDIYQKSIVSIRQQVIMNKIDKIE-LLKEVILGAETNKKINN--PTEKIIAQIENELNWK-KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENK------------NSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIP--GHFFKNKTLPID------IQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            + FT+D +   ++DDA+S      +  + VHI+DV  +V     +  +A+      Y P    +P   +    L  D LSL+PG+ R  +S+     +     K+ +F+          V+ S  +L+YEE    ++Q        PA +D+     + + Y      RH      ++ +  ++     +      A ++++E+M+  N  VA  +       T+  ++     R + L+ L E         L    +L G      ++R   + S   ++      +  D+++   L+  D+          D    +   ++  C+       GH+SL    YT  TSPIRR+ DVV+ R +   +        + DID +C   + +    +++++      +  +   +    LD +   ++ E       LL  ++ +       + + +L L E P             L WR+ ++S     PP  L  +  + +   +++ L+   L   +       + L QE       GEA + + L Q+    C  F                    +++  ++   +T+++Q       G +  +P+L+ V P F +CL H   P   F SG     ++   ++ +  + EY   +EP    ES   A+++  + TL+ + + W   ++ +T + +  G   L + F     +DI     Y +  R E L A       G SS+G  L        D   Y WV HG     ++    +++       L   +  + K  E V      FT+++  K +  +R++  +  +++   L+  + LG    + +    P+  +  Q  N    + K N +Q  AV+ AL +  ++I GPPGTGKT+VG ++ F +   N+++ +               +LYCGPSN  ++++A  ++ +   K    LR++ ++ E S+FP+P  G     +  P +      ++ ++LH  IR+    Y+ E+K FD   +  R       +      ++ YK ++ +A+K  +  ++ ++ILCT S      +   ++ Q+++DEAGM  EPETLIP+    ++ K VVL+GDHKQLRP++++      GL  SLFERY     E   ML+ QYRMH                                                     GI    SV  YK  LKT          W G R+ P    H   E  P  +IF  V G E S  V+T  GNE SK N  EV  V  I K+L        + P  I VLT Y+ Q      E    L ++      V ++ +SQGSE  YV+ STVR+    D++  PT  W +K LGF+ + NQ+NVA+TRA++GL +IG+  LL+    W+ L++  E +  ++
Sbjct:  772 LTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVP---MLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAP--------SVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRA-----AHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLAS--LWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQ---PLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGL---RLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQE------KGEASQRRELVQVQRSHCGHF--------------------LEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCF-SG----RVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSW---EASRTPQGQLQGAFRLEAAFLEENCADINFSCCY-LCIRLEGLPAPTASPRPGPSSLGPGL------NVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELK---PLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQ--RG------ELFSREDLVWYKKVLWEARKFEL--DRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEK-VVLLGDHKQLRPVVKNERLQNLGLDRSLFERYH----EDAHMLDTQYRMH----------------------------------------------------EGICAFPSVAFYKSKLKT----------WQGLRRPPSVLGHAGKESCP--VIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQL---TLGRTVEPQDIAVLTPYNAQAS----EISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2065
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Human
Match: HELZ2 (helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021])

HSP 1 Score: 345.895 bits (886), Expect = 5.519e-95
Identity = 351/1448 (24.24%), Postives = 615/1448 (42.47%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDD-----PANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYH-ISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDN-----RIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSC----PPY-LNSSSSNDNKFKIDSHLFDSYLPYSD-------SKLFQEIRRSYLSGEALENK-LNQL----CTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLR-SDIFHKEIYKIFNRYEYLIAS------GISSVGGDLLCLRCRKEDWNNY-WVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVN-----FTLDIYQKSIVSIRQQVIMNKIDKIE-LLKEVILGAETNKKINN--PTEKIIAQIENELNWK-KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENK------------NSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIP--GHFFKNKTLPID------IQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            + FT+D +   ++DDA+S      +  + VHI+DV  +V     +  +A+      Y P    +P   +    L  D LSL+PG+ R  +S+     +     K+ +F+          V+ S  +L+YEE    ++Q        PA +D+     + + Y      RH      ++ +  ++     +      A ++++E+M+  N  VA  +       T+  ++     R + L+ L E         L    +L G      ++R   + S   ++      +  D+++   L+  D+          D    +   ++  C+       GH+SL    YT  TSPIRR+ DVV+ R +   +        + DID +C   + +    +++++      +  +   +    LD +   ++ E       LL  ++ +       + + +L L E P             L WR+ ++S     PP  L  +  + +   +++ L+   L   +       + L QE       GEA + + L Q+    C  F                    +++  ++   +T+++Q       G +  +P+L+ V P F +CL H   P   F SG     ++   ++ +  + EY   +EP    ES   A+++  + TL+ + + W   ++ +T + +  G   L + F     +DI     Y +  R E L A       G SS+G  L        D   Y WV HG     ++    +++       L   +  + K  E V      FT+++  K +  +R++  +  +++   L+  + LG    + +    P+  +  Q  N    + K N +Q  AV+ AL +  ++I GPPGTGKT+VG ++ F +   N+++ +               +LYCGPSN  ++++A  ++ +   K    LR++ ++ E S+FP+P  G     +  P +      ++ ++LH  IR+    Y+ E+K FD   +  R       +      ++ YK ++ +A+K  +  ++ ++ILCT S      +   ++ Q+++DEAGM  EPETLIP+    ++ K VVL+GDHKQLRP++++      GL  SLFERY     E   ML+ QYRMH                                                     GI    SV  YK  LKT          W G R+ P    H   E  P  +IF  V G E S  V+T  GNE SK N  EV  V  I K+L        + P  I VLT Y+ Q      E    L ++      V ++ +SQGSE  YV+ STVR+    D++  PT  W +K LGF+ + NQ+NVA+TRA++GL +IG+  LL+    W+ L++  E +  ++
Sbjct: 1341 LTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVP---MLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAP--------SVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRA-----AHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLAS--LWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQ---PLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGL---RLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQE------KGEASQRRELVQVQRSHCGHF--------------------LEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCF-SG----RVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSW---EASRTPQGQLQGAFRLEAAFLEENCADINFSCCY-LCIRLEGLPAPTASPRPGPSSLGPGL------NVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELK---PLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQ--RG------ELFSREDLVWYKKVLWEARKFEL--DRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEK-VVLLGDHKQLRPVVKNERLQNLGLDRSLFERYH----EDAHMLDTQYRMH----------------------------------------------------EGICAFPSVAFYKSKLKT----------WQGLRRPPSVLGHAGKESCP--VIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQL---TLGRTVEPQDIAVLTPYNAQAS----EISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2634
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Human
Match: UPF1 (UPF1 RNA helicase and ATPase [Source:HGNC Symbol;Acc:HGNC:9962])

HSP 1 Score: 172.94 bits (437), Expect = 1.406e-42
Identity = 197/771 (25.55%), Postives = 319/771 (41.37%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL       ++D  ++++  I+ R   L+        GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PS    N+    + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  301 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAYFTLP------KTDSGNEDLVIIWLRDMRLMQ-------GDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPS----NIAVDQLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPI-RLQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 915
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Human
Match: UPF1 (UPF1 RNA helicase and ATPase [Source:HGNC Symbol;Acc:HGNC:9962])

HSP 1 Score: 169.088 bits (427), Expect = 2.358e-41
Identity = 194/771 (25.16%), Postives = 312/771 (40.47%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL     ++R                         + GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PSN  ++     + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  301 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAYFTLPKTDSDMRL------------------------MQGDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPSNIAVD----QLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPI-RLQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 904
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Human
Match: DIS3L (DIS3 like exosome 3'-5' exoribonuclease [Source:HGNC Symbol;Acc:HGNC:28698])

HSP 1 Score: 115.931 bits (289), Expect = 4.281e-25
Identity = 120/457 (26.26%), Postives = 196/457 (42.89%), Query Frame = 2 
Query: 1568 EISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQ--IVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQS-----DDPANVDAD----------LYMALESVYKIARKIRHARLPYSYF-VRSVKNCYT--------NLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVI---HKIDIDD---CSLDIDEICVNANTKSKYNKNFEK 2842
            ++SP+ E++ K +R+ H+              VF+ID K  +D+DD +S  R +N   + +GVHI+DVT +V+P S +  +A+    T+Y   YL    Y +    L+ D  SL+ G  R  VS++++  +     K   +           +I S YKL YE     L  +     D P   D D          L  A+  +  IAR +R  R       +  V+ C          +L  +   E    + E M+LAN +VA+ I+E +P+  LLR   P               +  F  +L+E     G           FI +R    L +     +D         +D   N     +     +SN  Y++          H+ L    YTHFTSPIRR++D+VVHRLL + I    K++I      + D++E+C + N +++  ++ +K
Sbjct:  456 KVSPEEEQKRKDLRKSHL--------------VFSIDPKGCEDVDDTLSV-RTLNNGNLELGVHIADVTHFVAPNSYIDIEAR-TRATTY---YLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYG--------RTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPP--------------PHQEFFSELRECAKAKGF----------FIDTRSNKTLADSLDNAND--------PHDPIVNRLLRSMAT-QAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQK 852
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Celegans
Match: smg-2 (Regulator of nonsense transcripts 1 [Source:UniProtKB/Swiss-Prot;Acc:O76512])

HSP 1 Score: 155.606 bits (392), Expect = 1.059e-37
Identity = 157/565 (27.79%), Postives = 243/565 (43.01%), Query Frame = 2 
Query: 4154 KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVK----KAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKL--KPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIG-EEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            + N +Q  AVK  L + LSLI GPPGTGKT+V    +  Y  V + E     VL C PSN  ++ +A    EK ++   K++R+  + +E S+  +P               ++L   ++  GG   EL+K       I+ KD            L +K+ ++    K  KE+ +    D+I CT S      ++      V+IDE+    EPE L+ I    + V+ +VL+GDH QL P++  + A   GL  SLFER   L  +P     L +QYRMHP + +FPS  FY G L   V+         HM                     G+D+                       WP   K  F               F    G EE+S S T+         N+ E   V  +  KL++      + P+ I V+T Y  Q+  +   M  +  L  K   +  + +V   QG E DY+I + VRS +I  I             GF+++  ++NVA+TRAK GL+++GN ++L  +  W +LI + + +  +    +N
Sbjct:  445 ELNSSQMQAVKQVLTRPLSLIQGPPGTGKTVVSA--TIVYHLVQKTEGN---VLVCSPSNIAVDHLA----EKIHKTGLKVVRLCARSREHSETTVP--------------YLTLQHQLKVMGGA--ELQKL------IQLKDEA--------GELEFKDDLRYMQLKRVKEHELLAAADVICCTCSSAADARLSKIRTRTVLIDESTQATEPEILVSIM---RGVRQLVLVGDHCQLGPVVICKKAAIAGLSQSLFERLVLLGIRP---FRLQVQYRMHPVLSEFPSNVFYDGSLQNGVTE-----NDRHM--------------------TGVDWH----------------------WPKPNKPAF---------------FWHCSGSEELSASGTSFL-------NRTEAANVEKLVSKLIKAG----VQPHQIGVITPYEGQRSFIVNYMHTQGTLNSKLYENVEIASVDAFQGREKDYIIVTCVRSNDILGI-------------GFLSDPRRLNVAITRAKYGLVLVGNAKVLARHDLWHELINHYKSKEMLYEGPIN 878
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Celegans
Match: smg-2 (Regulator of nonsense transcripts 1 [Source:UniProtKB/Swiss-Prot;Acc:O76512])

HSP 1 Score: 155.606 bits (392), Expect = 1.059e-37
Identity = 157/565 (27.79%), Postives = 243/565 (43.01%), Query Frame = 2 
Query: 4154 KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVK----KAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKL--KPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIG-EEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            + N +Q  AVK  L + LSLI GPPGTGKT+V    +  Y  V + E     VL C PSN  ++ +A    EK ++   K++R+  + +E S+  +P               ++L   ++  GG   EL+K       I+ KD            L +K+ ++    K  KE+ +    D+I CT S      ++      V+IDE+    EPE L+ I    + V+ +VL+GDH QL P++  + A   GL  SLFER   L  +P     L +QYRMHP + +FPS  FY G L   V+         HM                     G+D+                       WP   K  F               F    G EE+S S T+         N+ E   V  +  KL++      + P+ I V+T Y  Q+  +   M  +  L  K   +  + +V   QG E DY+I + VRS +I  I             GF+++  ++NVA+TRAK GL+++GN ++L  +  W +LI + + +  +    +N
Sbjct:  445 ELNSSQMQAVKQVLTRPLSLIQGPPGTGKTVVSA--TIVYHLVQKTEGN---VLVCSPSNIAVDHLA----EKIHKTGLKVVRLCARSREHSETTVP--------------YLTLQHQLKVMGGA--ELQKL------IQLKDEA--------GELEFKDDLRYMQLKRVKEHELLAAADVICCTCSSAADARLSKIRTRTVLIDESTQATEPEILVSIM---RGVRQLVLVGDHCQLGPVVICKKAAIAGLSQSLFERLVLLGIRP---FRLQVQYRMHPVLSEFPSNVFYDGSLQNGVTE-----NDRHM--------------------TGVDWH----------------------WPKPNKPAF---------------FWHCSGSEELSASGTSFL-------NRTEAANVEKLVSKLIKAG----VQPHQIGVITPYEGQRSFIVNYMHTQGTLNSKLYENVEIASVDAFQGREKDYIIVTCVRSNDILGI-------------GFLSDPRRLNVAITRAKYGLVLVGNAKVLARHDLWHELINHYKSKEMLYEGPIN 878
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Celegans
Match: smg-2 (Regulator of nonsense transcripts 1 [Source:UniProtKB/Swiss-Prot;Acc:O76512])

HSP 1 Score: 155.606 bits (392), Expect = 1.059e-37
Identity = 157/565 (27.79%), Postives = 243/565 (43.01%), Query Frame = 2 
Query: 4154 KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVK----KAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKL--KPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIG-EEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            + N +Q  AVK  L + LSLI GPPGTGKT+V    +  Y  V + E     VL C PSN  ++ +A    EK ++   K++R+  + +E S+  +P               ++L   ++  GG   EL+K       I+ KD            L +K+ ++    K  KE+ +    D+I CT S      ++      V+IDE+    EPE L+ I    + V+ +VL+GDH QL P++  + A   GL  SLFER   L  +P     L +QYRMHP + +FPS  FY G L   V+         HM                     G+D+                       WP   K  F               F    G EE+S S T+         N+ E   V  +  KL++      + P+ I V+T Y  Q+  +   M  +  L  K   +  + +V   QG E DY+I + VRS +I  I             GF+++  ++NVA+TRAK GL+++GN ++L  +  W +LI + + +  +    +N
Sbjct:  445 ELNSSQMQAVKQVLTRPLSLIQGPPGTGKTVVSA--TIVYHLVQKTEGN---VLVCSPSNIAVDHLA----EKIHKTGLKVVRLCARSREHSETTVP--------------YLTLQHQLKVMGGA--ELQKL------IQLKDEA--------GELEFKDDLRYMQLKRVKEHELLAAADVICCTCSSAADARLSKIRTRTVLIDESTQATEPEILVSIM---RGVRQLVLVGDHCQLGPVVICKKAAIAGLSQSLFERLVLLGIRP---FRLQVQYRMHPVLSEFPSNVFYDGSLQNGVTE-----NDRHM--------------------TGVDWH----------------------WPKPNKPAF---------------FWHCSGSEELSASGTSFL-------NRTEAANVEKLVSKLIKAG----VQPHQIGVITPYEGQRSFIVNYMHTQGTLNSKLYENVEIASVDAFQGREKDYIIVTCVRSNDILGI-------------GFLSDPRRLNVAITRAKYGLVLVGNAKVLARHDLWHELINHYKSKEMLYEGPIN 878
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Celegans
Match: disl-2 (DIS3-like exonuclease 2 [Source:UniProtKB/Swiss-Prot;Acc:Q09568])

HSP 1 Score: 101.679 bits (252), Expect = 3.482e-21
Identity = 112/413 (27.12%), Postives = 171/413 (41.40%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYH-------REMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDD-------PANVDADLYMALES----VYKIARKIRHAR---------LPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFF--ELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVI-HKIDIDDCSLDIDEICVNAN 2809
            IVFTID KT +D+DDA+          +    + IGVHI+DVT ++   +E+ K A +   ++Y  + + IP   +    L     SL PG  R   S +FK S           +++    F   VI S+ KL YE    +++  +        P   D +    ++     +++IA+ +R  R         LP   F          +      ++  L+EEFMLLAN  VA+ I E +P   LLR   P K +                  + E C  +G     R S       RK+      +  I+Q         +Q  +YF  F + ++ +YH                  HF+LN   YTHFTSPIRR+ DV+VHR L + + +    +    +I EIC   N
Sbjct:  340 IVFTIDPKTARDLDDALHAKHIDDCDGKGTPGLEIGVHIADVTFFLKEGTELDKWASERGNSTYLSQTV-IP---MLPRILCEQLCSLNPGVDRLSFSTVFKMSYE---------AELYDVWFGRSVIRSRVKLAYEHAQDFIENPEKDFTCDELPDISDGNTPFEIKEKTLMLHRIAQVLRQKREDSGALRIELPRLKFALDEDKKPQGVSIYEIKDSNKLVEEFMLLANMEVAKKIAENFPEHALLRNHPPPKEK--------------MIKDVAEQCARIGFPLDGRTSGLLSTSLRKYQGKSRLDMCIRQVISSLTIKPMQQAKYFCTFEMPLS-FYH------------------HFALNVDHYTHFTSPIRRYPDVIVHRQLAAALGYNERSERVPEEIQEICTRCN 706
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Celegans
Match: dis-3 (Probable exosome complex exonuclease RRP44 [Source:UniProtKB/Swiss-Prot;Acc:Q17632])

HSP 1 Score: 98.2117 bits (243), Expect = 3.767e-20
Identity = 102/402 (25.37%), Postives = 179/402 (44.53%), Query Frame = 2 
Query: 1664 VFTIDNKTTKDMDDAISYHREMNQIV--IGVHISDVTKYVSPTSEMYKQAKDCFCTSYP-PKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENR----------FEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLD---IDEICVNANTKSK 2821
            + ++D     D+DDA+ + +++ + +  +GVHI+DVT +V P + +  +A     T Y   + +++ P       L+++  SL   + R   S ++  + +         +DI   ++ + +I SK  L YE+    +   DDP   + D+ + L  + K+++ +   R        +      ++  E+R           +   ++EEFMLLAN  VA  I E+YP+  LLR + PV  +E +   +  + +  F   ++    L   L  NR   +K  +  +   +             +C+ Q   YF+   V +        P Y            HF L  ++YTHFTSPIRR+ DV+VHRLL + I   DI    L+     +IC N N + K
Sbjct:  487 ICSVDPLGCTDIDDAL-HCKQIGEDLFEVGVHIADVTHFVRPGTAIDDEAALRGTTVYLCDRRIDMLPC-----LLSSNLCSLRGEEERYAFSCIWTMTSS---------ADIQSVKYHKSLIKSKAALTYEKAQEII---DDPKEQN-DVALGLRGLMKLSKVLNARRTGNGALTLASSEVRFDMDWESRTPKKVMEKQHLDTHSMVEEFMLLANISVAEKILEEYPDCALLR-RHPVPLKESYKPLVEAARHRGFEIIVESGKGLADSL--NRCVDKKNPMLNRLLRMLT----------TRCMTQA-VYFSAGTVPV--------PQYQ-----------HFGLACAIYTHFTSPIRRYADVIVHRLLAAAIGADDIQSGLLNQARCTKICTNINYRHK 836
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Fly
Match: Upf1 (gene:FBgn0030354 transcript:FBtr0342744)

HSP 1 Score: 121.709 bits (304), Expect = 3.869e-27
Identity = 121/419 (28.88%), Postives = 189/419 (45.11%), Query Frame = 2 
Query: 3803 GDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNK--IDK---IELLKEVILG---AETNKKI--NNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKL--KPELVTMLNLQYRMHPSICDFPSMEFYSGKL 5023
            GD L L    E +N  W   GHV+ +     ++  ++L      +S+ + P    + NFT+D   K     R    + K  ID+      +   +LG   A++N ++    P  K+ +      +    NR+Q  AVK+AL + LSLI GPPGTGKT+    + +    ++        VL C PSN  ++     + EK +    K++R+  K +E  D P              +  ++LH  IR N     ELKK   +      KD      +       Y+NL + A+ + +     D+I CT        ++      ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A + GL  SLFER   L  +P     L +QYRMHP +  FPS  FY G L
Sbjct:  336 GDELRLHYVGELYNP-WSEIGHVIKVPDNFGDDVGLEL------KSSTNAPVKCTS-NFTVDFIWKCTSFDRMTRALCKFAIDRNSVSNFIYSRLLGHGRADSNDEVLFRGPQPKLFSAP----HLPDLNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLH-----GGTVLVCAPSNTAVD----QLTEKIHRTNLKVVRVCAKSREAIDSP--------------VSFLALHNQIR-NMETNSELKKLQQL------KDETGELSSADEK--RYRNLKRAAENQLL--EAADVICCTCVGAGDGRLSRVKFTSILIDESMQSTEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVLGIRP---FRLEVQYRMHPELSQFPSNFFYEGSL 702

HSP 2 Score: 67.3958 bits (163), Expect = 1.345e-10
Identity = 54/185 (29.19%), Postives = 86/185 (46.49%), Query Frame = 2 
Query: 5273 PERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            PER +F  V     +Q      G+  S  N+ E   V  I  + L+      + P  I ++T Y  Q+  L   M+ +  L  +      + +V   QG E D +I S VRS              E++ +GF+ +  ++NVALTRAK G+II+GN ++L   Q W  L+   ++R  ++   LN
Sbjct:  722 PERPMFFLV-----TQGQEEIAGSGTSFLNRTEAANVEKITTRFLKAG----IKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRSN-------------ERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQLWNHLLNFYKDRKVLVEGSLN 884
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Fly
Match: Upf1 (gene:FBgn0030354 transcript:FBtr0073596)

HSP 1 Score: 121.709 bits (304), Expect = 3.869e-27
Identity = 121/419 (28.88%), Postives = 189/419 (45.11%), Query Frame = 2 
Query: 3803 GDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNK--IDK---IELLKEVILG---AETNKKI--NNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKL--KPELVTMLNLQYRMHPSICDFPSMEFYSGKL 5023
            GD L L    E +N  W   GHV+ +     ++  ++L      +S+ + P    + NFT+D   K     R    + K  ID+      +   +LG   A++N ++    P  K+ +      +    NR+Q  AVK+AL + LSLI GPPGTGKT+    + +    ++        VL C PSN  ++     + EK +    K++R+  K +E  D P              +  ++LH  IR N     ELKK   +      KD      +       Y+NL + A+ + +     D+I CT        ++      ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A + GL  SLFER   L  +P     L +QYRMHP +  FPS  FY G L
Sbjct:  336 GDELRLHYVGELYNP-WSEIGHVIKVPDNFGDDVGLEL------KSSTNAPVKCTS-NFTVDFIWKCTSFDRMTRALCKFAIDRNSVSNFIYSRLLGHGRADSNDEVLFRGPQPKLFSAP----HLPDLNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLH-----GGTVLVCAPSNTAVD----QLTEKIHRTNLKVVRVCAKSREAIDSP--------------VSFLALHNQIR-NMETNSELKKLQQL------KDETGELSSADEK--RYRNLKRAAENQLL--EAADVICCTCVGAGDGRLSRVKFTSILIDESMQSTEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVLGIRP---FRLEVQYRMHPELSQFPSNFFYEGSL 702

HSP 2 Score: 67.3958 bits (163), Expect = 1.345e-10
Identity = 54/185 (29.19%), Postives = 86/185 (46.49%), Query Frame = 2 
Query: 5273 PERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            PER +F  V     +Q      G+  S  N+ E   V  I  + L+      + P  I ++T Y  Q+  L   M+ +  L  +      + +V   QG E D +I S VRS              E++ +GF+ +  ++NVALTRAK G+II+GN ++L   Q W  L+   ++R  ++   LN
Sbjct:  722 PERPMFFLV-----TQGQEEIAGSGTSFLNRTEAANVEKITTRFLKAG----IKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRSN-------------ERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQLWNHLLNFYKDRKVLVEGSLN 884
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Fly
Match: CG7504 (gene:FBgn0035842 transcript:FBtr0273368)

HSP 1 Score: 104.76 bits (260), Expect = 7.661e-22
Identity = 108/364 (29.67%), Postives = 164/364 (45.05%), Query Frame = 2 
Query: 4172 YNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVA---STMMEKFNEKCPKLLRIFGKEQEVSDFPIP----GHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTY--KNLVKKAKKEYIVKNKFDM-------------------ILCTT---SVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQK-LKPEL------------VTMLNLQYRMHPSICDFPSMEFYSGKLITH------VSPL--WCGLKSDHMKVFCHSSDSSKK 5107
            Y  + + L   L+LI GPPGTGK+ V   L     + N  +  +  +L C  SN  ++ +     +++   N     LLR FG  +++S +  P     HF K K       E  L  + ++N   A+ LKK  N       KD I       N   TY  + L +K KK  ++ N+                      I+CTT    V L   V FF+I   I+DEA  C EP TL+P+      + ++VL+GD +QL  ++ S+ A   GL  S+F+R Q+ L+ +L            +  L+ QYRMHP IC +P+  FY  +LI         SPL  +C +   ++K  C S+ +  K
Sbjct:  925 YQRIIDDLQPSLTLIQGPPGTGKSRVISELCLQTLYGNAAKTLDRKILICAHSNTAVDHIVGLLGSVLRVMNRDQFHLLR-FGMHEKMSHYSRPFSLEAHFNKAK-------EQKLQRVSKEN---AEILKKQHNDL-----KDEIQQLKEKTNLTSTYLLQQLQQKEKKLQLISNQLSPPLTQREEFEISHMCVTRANIICTTLSSCVKLANYVDFFDIC--IVDEATQCTEPWTLLPMRFG---LTHMVLVGDMQQLPAVVLSKKAIDFGLSNSMFDRIQRSLQTQLDKPGSYHLMHTKLFKLSTQYRMHPEICRWPNQYFYEDQLINAECTARFASPLIPYCVI---NLKYTCDSNGAQNK 1264
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Fly
Match: Dis3l2 (gene:FBgn0035111 transcript:FBtr0072487)

HSP 1 Score: 103.99 bits (258), Expect = 9.213e-22
Identity = 107/386 (27.72%), Postives = 168/386 (43.52%), Query Frame = 2 
Query: 1664 VFTIDNKTTKDMDDAISYHR-EMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWL-------KQSDDPANVDA----DLYMALESVYKIARKIRHARL----------PYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDS--VNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVI 2749
            +FTID  T +D+DDA+S  +   N+  IGVHISDV+ ++   +E+    K+   TS    YL     H+  + L     SL+PG+ +   SV ++     +N K        +PEF   VI S  +  YE     +        ++D P  ++     D+   +  ++ IA  IR  RL             + +  +     + + E + EA  LIEEFMLLAN+ VAR I++ +P+  +LR   P                      LK     L  L F  +      +      L NE       +   CL Q                 ++  +Y+ CSE  S   ++ H++L+  +YTHFTSPIRR+ D++VHRLL + +
Sbjct:  556 IFTIDPMTARDLDDAVSIEKLGDNEYEIGVHISDVSHFLIEDNELDNIVKE-RSTSI---YLANEVIHMLPQSLCMR-CSLLPGQDKFAFSVFWR-----MNGKGVMLQK--KPEFCRTVINSCSQFAYEHAQKIIDNPNERFTENDFPTILNGFNPDDIRNRVLWLHDIASSIRKTRLDNGALTINNAKLRFLLDPITGEPLSFEVEKQREANRLIEEFMLLANQAVARFIHDSFPDIAVLRNHPP-----------------PLIKSLKALREKLLALGFELDYSSSKALQESMVRLCNEAPNPVAMN--ACLSQL------------LMKPMARATYF-CSEGKSEPADLWHYALSIPIYTHFTSPIRRYPDILVHRLLAAAL 897
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Fly
Match: Dis3l2 (gene:FBgn0035111 transcript:FBtr0072486)

HSP 1 Score: 103.99 bits (258), Expect = 9.456e-22
Identity = 107/386 (27.72%), Postives = 168/386 (43.52%), Query Frame = 2 
Query: 1664 VFTIDNKTTKDMDDAISYHR-EMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWL-------KQSDDPANVDA----DLYMALESVYKIARKIRHARL----------PYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDS--VNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVI 2749
            +FTID  T +D+DDA+S  +   N+  IGVHISDV+ ++   +E+    K+   TS    YL     H+  + L     SL+PG+ +   SV ++     +N K        +PEF   VI S  +  YE     +        ++D P  ++     D+   +  ++ IA  IR  RL             + +  +     + + E + EA  LIEEFMLLAN+ VAR I++ +P+  +LR   P                      LK     L  L F  +      +      L NE       +   CL Q                 ++  +Y+ CSE  S   ++ H++L+  +YTHFTSPIRR+ D++VHRLL + +
Sbjct:  568 IFTIDPMTARDLDDAVSIEKLGDNEYEIGVHISDVSHFLIEDNELDNIVKE-RSTSI---YLANEVIHMLPQSLCMR-CSLLPGQDKFAFSVFWR-----MNGKGVMLQK--KPEFCRTVINSCSQFAYEHAQKIIDNPNERFTENDFPTILNGFNPDDIRNRVLWLHDIASSIRKTRLDNGALTINNAKLRFLLDPITGEPLSFEVEKQREANRLIEEFMLLANQAVARFIHDSFPDIAVLRNHPP-----------------PLIKSLKALREKLLALGFELDYSSSKALQESMVRLCNEAPNPVAMN--ACLSQL------------LMKPMARATYF-CSEGKSEPADLWHYALSIPIYTHFTSPIRRYPDILVHRLLAAAL 909
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Zebrafish
Match: si:dkey-97a13.6 (si:dkey-97a13.6 [Source:ZFIN;Acc:ZDB-GENE-070912-617])

HSP 1 Score: 367.851 bits (943), Expect = 3.138e-102
Identity = 368/1435 (25.64%), Postives = 621/1435 (43.28%), Query Frame = 2 
Query: 1688 TKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYK----LNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCY-TNLQTENRFEAELLIEEFMLLANEYVARIIYEK--YPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQ---KFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYY----NCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEII-CAHPLLQVASSDN-RIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHL----FDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNY-----------WVGHGHVVTINKCMINN-QKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKI-ELLKEVILGAETNKKINNPTEK-----IIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRK----------ENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPG------HFFKNKTLPIDIQEVSLHFLIR-KNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNA-ILTYKNLVKKAKKEYIVKNKFDMILCT-TSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFP----PRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIA 5809
            +  + DAIS         IG+H +D   YVS                           +I +    +D  +L PGK R  +S++ K     +  +N K  +       E +++S+ +    L+Y E    + Q  +       L   +  V + A   R  RL      R V +   ++L +    +  L++EE  L+      +II ++  +PN++   + + +K   E  E+L          Q+ E C        + N+ Q    FI+    ++         DF K   L+  D+   +    I       N +++    +C E     +GH+SL+   YTH +SPIRR+ DVV+ RL+ +V+    ++    DID +C       K  + +E   E   I     K+    +  V     D E    + P  +    +   +++ NL L++ P+  K  ++     L W+K I+     L+ + S     KI S +    + + +     + + E +   L+    +N  N   +                S  +   D ++++ V +T+++Q    +  G      +LF ++ SF IC+ H +NP K F       +  +  K S+S+++EY   + PL E ES   A+ D     +E V I W   +              LS +F     +I    I       E+        +G  LLC+R R  + N             WV H      +    N+  K K+I F +  ++  +PK   N  FT++I  K +  IR++  +N +    EL++ + L    ++ +N  + +     ++ + E      + N +Q+ A++ ALN K ++I GPPGTGKT+VG Y+ + ++ +N +          ++K  V+LYCGPSN  +++VA  ++ KF EK  KLLR++ ++ E+ ++P PG      H  + +    +++ ++LH  IR  +  Y+  +  FD+  K     DP    +++ +  I  YK L+  A+   +   + D+ILCT T+     +    +  Q++IDE  M  EP+TL+P+ +     + VVL+GDHKQLRP++++    + G+  SLFERY     +   ML+ QYRMH  IC FPS  +Y+  L T V                                                +TS  NA  + +   KR                 I+F D+ GEEI   V+T  GNE SK N  EV       KK +E C       R+ P  I +L+ Y+ Q   +        LK  T    V T+ +SQGSE  YVI S VRS   ++I   P+  W  KH+GF+ + NQINV +TRA+ GL I+GN+ +L  +  W+KL+++     CV+ 
Sbjct:  948 SSQLRDAISVSESEFHFEIGIHKADFLNYVSED-------------------------NIQNLGAQSDMWNLAPGKKRCAISLMLK-----VEKRNGKLVE-------EKMVLSRIRSCKALSYSEADSIINQLGEKEMKFGTLEDCILVVCRFALDHRTKRLS-----RQVNSSNPSDLASSEDSKCRLMMEELKLMFKRASDQIINQQTQFPNTSP-GLVNRLKKYNEKFESL----------QVLEKC-------LDPNNGQNCGSFIILTSVWKKIKSAALTCDFYKMADLISTDDIHPQLVPAIVQLSASINKAFFIRSLSCRE---ALVGHYSLHLDSYTHASSPIRRYIDVVLQRLMHAVLGNRPVEYSQTDIDLLCEKCKRGEKRAQEYESKVEALQIAVNLQKQSTYKVAFVTVVKRDSESFKLSFPFDKGTFPEKLPVQYRNLQLEDQPLFIKKPKHV---KLTWKKRIYG----LSMTQSPLQNMKISSEIQQSTWQAIVEAVRDEKWDEAKSLVLAAHVKDNSRNSELSD----TSRWDPDRTFTSEEDHYTDFQINLKVGDTVQVQLTSERDRGYWAPTVQLFRLSSSFEICVEHTDNPIKCFSR-----IADHPSKGSYSNVEEYVQIWRPLCEMESAATAVDDSDCVVIENVAITWDDSR--------------LSGNFSLPEENIKKWAI-------EF-------DLGRCLLCIRKRDLEQNQAEQSELDPKYFTWVAHAVTTLCSDSPENSGNKFKIINFNVKYASMKIPKFKRNETFTVEIIPKLLPDIRKESAVNNLKGANELVQNIAL---KHRIVNQSSNQDVPLYLLMREEAPAGLPQLNESQFKALEKALNGKFTIIQGPPGTGKTVVGAYIVYWFSQLNSRNLWRLKDPTDKDKREVILYCGPSNKSVDVVAEYLL-KFGEKL-KLLRVYSRQMEMQEYPYPGSNLQLSHKSRQERSKPELRAITLHHRIRMGHNPYSQRITDFDDRIK----SDP----YSLTDTDIEEYKKLLNDARLHEL--ERHDIILCTCTAAASPNLKKTLSARQILIDECAMATEPQTLVPLVSFKP--EKVVLLGDHKQLRPIVKNNHVRRLGMTRSLFERYM----DRAIMLDTQYRMHEEICKFPSEAYYNDMLKTVVRE----------------------------------------------RTSVLNAETEGRRQSKR-----------------ILFGDIRGEEIGLVVSTARGNENSKANFDEV-------KKAVEICIQLVTVGRVRPEDIAILSPYNAQVAQIRERLSDFELKGFT----VTTITKSQGSEWQYVILSIVRSCPSDEIEPMPSREWLSKHIGFVGDENQINVGITRAQVGLCILGNQAVLNCSPAWQKLLKHYSGHGCVVT 2180

HSP 2 Score: 88.5817 bits (218), Expect = 8.556e-17
Identity = 134/505 (26.53%), Postives = 207/505 (40.99%), Query Frame = 2 
Query:  935 QSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKII--NEKFHSGKVMGVYQSFHKPVNKLYVC----------KVSKDQG---NLMVPLDKSFPKIH--VENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSE--NMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNL---QTENRFEAELLIEEFMLLANEYVARII--YEKYPNSTLLRMQ-SPVKNREEWLENLH 2374
            QSG  IP +N + +    I +  R+N G + F  D V V+I   +E   +G+V+G+  +   P +   VC          K++ DQ     +M+PLD +  KI   V+  A + +   K  + N TI+                             IN+ T                   Y+FVV    W  H  +P GR+   L    SL++ L ++++   L    +SP   +E  T+ E  + +D       +G   FT+D    + +DDAIS +   +   IGVH++DV  +VS  S +   AKD   T Y P      P  +F + L+T   SL+PGK R  +S++ +  +   +I  K F  S          ++ SK +L Y E    + Q D     D  L   +   Y  AR  R  RL   +        Y  L   Q     EA  +IEE  ++ N  V++ +  Y    + T LR Q SP     E + N H
Sbjct:  467 QSGYIIPYDNPSER----IDIKGRKNIGMS-FPGDEVVVEIRRHDEGHLTGRVLGL--TNRSPTSSECVCSLEDENYNRKKLNPDQNLVPKMMIPLDHTTTKIRILVKKEARKLIPLWKCVSGNWTITGR-------------------------VPINEQTKQ----------------NYVFVVQILGWKEHCSFPLGRVTDILPVGTSLEEGLKILKSEFKL----MSPPLMQE-NTLLE--IRIDDKRRKDFTGLKTFTVDPPNAEVLDDAISINDLGSCYEIGVHVADVASFVSKDSSIDAFAKDMGATFYAP---GKEPAFMFPKHLSTTCWSLLPGKDRKAISLIVEVEKQSGVITKKTFDLS----------MVKSKRQLTYNEAEDIICQCDGELRFDT-LEDCVRVAYHFARSQRKTRLKEDW-------SYAQLNKHQKPGEREAHRMIEELNIMFNHEVSKFLSEYTDTKSCTPLRCQDSPNAEALEKISNQH 895

HSP 3 Score: 52.373 bits (124), Expect = 8.150e-6
Identity = 54/177 (30.51%), Postives = 74/177 (41.81%), Query Frame = 2 
Query: 4634 LVKKAKKEYIVKNKFDM-----ILCTTSVT-----LKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRG---LQISLFERYQKLKPELV----TMLNLQYRMHPSICDFPSMEFYSGKLI-----THVSPLWCGLKSDHMKVFCHSSDS 5098
            L  +  + +I+  + D+     I+ TTS+      LK    FF    ++IDEA    E E L+ +  A K  + VVL GDH Q+ P + S   DKR    L   LF  YQ     +      + N  YR    I DF S  FY    I      H  P    L   H++  CH S +
Sbjct:   48 LCSRDGQSFILPARSDLESHRIIITTTSIARHLHELKLPKGFF--THILIDEASQMLEGEALMALGLADKHTR-VVLAGDHMQMAPKLFSVTDDKRSEHTLLNRLFHYYQDQSINIAKKSRIIFNENYRSTTEIVDFVSTYFYVSDGIKARGDVHPHPRLKPLIFHHVRGECHLSST 221
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Zebrafish
Match: helz2 (helicase with zinc finger 2, transcriptional coactivator [Source:ZFIN;Acc:ZDB-GENE-120920-1])

HSP 1 Score: 301.982 bits (772), Expect = 8.762e-82
Identity = 358/1435 (24.95%), Postives = 627/1435 (43.69%), Query Frame = 2 
Query:  989 IILTSRQNCGFNVFLNDIVYVKIINEKFHS--GKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNK-----IKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKT-IREKHMILDKPHI---------TLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQ---TENRFEAELLIEEFMLLANEYVA-RIIYEKYPNS-TLLRMQSPVKNREEWLENLHESTNL-----NFAGQLKEYCNLLGVLNFN-RNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNE---FYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTK----SKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDN-RIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSK----------------LFQEIRR-SYLSGEALENKLNQL-CTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLS-----SDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVV----TINKCMINNQ----KMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKI-ELLKEVILGAETN-----KKINNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAY----TFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFK-------NKTLPIDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCT-TSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHV 5035
            I +  R N G   F  D V V+I++   H   G+V+ + +S      K +VC + +    +M P++K   KI          +K+K     ++N  +++  E+   +++E +R S                                       LF+V    W   F YP G +VG L    +L D          L++L I  +  + + + +R++   L +  I          LP+    FT+D   ++D+DDAIS       + IGVHISDV  +V+  SE+ K A+   CT++ P+     P ++F ++L+T+ LSL+P + R  +S++ +  +   N    +F         + VI S  K +Y+EV   L+  +  +++   L + L  V   A   R  R    +       CY       T  R  +  ++EE M++ N  VA R++ +    S T LR Q   +  ++ +E   ++  L     +F+ Q  E  N  G++  N +     F V +          +Q +  K    +  D+   +   F V     +H +     N +    +  GH+ L+   YT  +SP+RR+ DV+V RLL SVI K D+   +LDI+  C+  + K    S Y +    L     +  ++ ++   I++      N      + PL + + S+N  I   +L L   P    +N +     LKW + I+S   + NS    + K +  + +  +Y+P    K                L +E++R S ++       L+   CTK           +      E   ++ L +     + +Q     A GLM  + +LFVV P F IC+ H  +P K F      +   ++ + S++  K+Y+  + P+ E ES   A+++  +  +  V +KW   ++   K+ + + ++ L      S  C+LR+        +I  +    + S  ++   D+             WV HG +     T +K   N +    ++  +I  +  +N       E   FTL++  K +  +R++  ++ + K  +L+K + +G         K  N  T +      +       N +Q  A++ AL    +LI GPPGTGKT+VG ++ +        +    +K   +LYCGPSN  +++VA  ++   +   P  LR++  + E+ +FP PG   K        +    ++  ++LH LIRK G  ++ +++ FD   K  R       +  ++  IL      KKA+K  ++ +  D+ILCT T+ +   +    +  Q+IIDE  M  EPE  IP+ A     + +VL+GDHKQL+P++   +A++ G+  SLFERY     E   ML+ QYRM   IC FPS EFY G+L T +
Sbjct: 1166 IDIKGRANIG-RAFPGDKVTVEILSATSHPPMGRVINILES--ADTVKEFVCALERHDNQVMTPINKCITKIFTP------FWKDKPNHIAVRNP-ESLKVEKFIKINEEAHRKS---------------------------------------LFIVKVLSWRNVFRYPLGIVVGVLPKIATLDD---------GLHVLSIEYQLRRTLSSSLRKQMQYLQRLDIFEKGRRDFRMLPT----FTVDPAHSQDLDDAISLQDFGEYLEIGVHISDVASFVAKDSELDKFARQ-LCTTFYPR--EKEPIYMFPKELSTNLLSLIPNQDRRAISLIIEV-DAQTNRIKRRF-------ICKSVIHSNRKFSYDEVEDILENGEPLSDL---LEICLVKVSNFAEVHRRYRKQDDW-------CYKMPDEDVTLGRRRSHQMVEELMVMFNHMVAERLLSDGATRSKTPLRCQDRPQT-DKLIEIFDKNAALIPLSVHFSSQAHEL-NKQGLIQHNPQTDSDTFPVLKSILRCLKSAAEQENIYKIIDFVATDDIHPQLLPFAVAFRRLFHKACIQRSNSTHVSRI--GHYDLDLDSYTWASSPVRRYLDVIVQRLLHSVIDKTDVKYTTLDINLSCLEFSRKNDQQSAYERKANALHFALKLSSQSERKVAYIVELNPLGTN---FKVSFPLNRSSISENLDIMSRDLLLAVQPEFDVTNNSMI---LKWERRIYS---FSNSHIHAEVKQQNPNSVM-AYVPAKTWKCIADAIREQNWNAIFPLIEELQRNSGINARQFHETLSASKCTK-----------NYDPLHAEHYAELYLRIKQGEAVEVQLGASTARGLMTPSIQLFVVHPKFEICVEHVRDPVKCFS-----EYALSSSRSSYNLYKDYQAIWRPMCEMESASSAVAENESILIVDVPLKW---ENSNPKRLQGFFLLPLDKKSQWSIDCDLRNSFLCIRT-RIQKQSSPFLESAQNTALMDIPSF---------TWVVHGVITEAEETESKESTNQEPKSLRIDFLINHMPMTNIPEQIFHERTRFTLELIPKLLPDVRKENAIDSLTKANQLVKNIAMGRRITSDRGCKIPNQNTGRFEINSYHPSGLSHLNNSQSKAIREALTNPFTLIQGPPGTGKTVVGVHILYWLHKNIQQLQASGSKKRAILYCGPSNKSVDVVAGHLLHLRDHLKP--LRVYSDQMEMLEFPYPGCNLKLSRNSKRGEKPNTELSSIALHHLIRKEGNPFSTQIRAFD--MKVQRGDQLTDEERKLFREIL------KKARKHELLHH--DVILCTCTAASHPALAETLDFKQIIIDECAMATEPEAFIPLVA--HKPEQIVLLGDHKQLQPVVHCEVAERLGMSRSLFERYM----ENALMLDTQYRMQEDICAFPSNEFYGGRLQTGI 2456

HSP 2 Score: 114.39 bits (285), Expect = 1.158e-24
Identity = 70/175 (40.00%), Postives = 98/175 (56.00%), Query Frame = 2 
Query: 5282 IIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            I+F  V G+E S  V T  GNE SK N  E E V  +   L E      +    I +LT Y+ Q   +     +  ++  T    V T++RSQGSE  YVI STVRS    +I   P   W  K LGFIT+ +Q+NV +TRA++GL IIGN+ LL+ +  W+KL+ + +E+ CV+
Sbjct: 2472 IVFGHVEGKEKSLVVRTEQGNENSKANMEEAEEVVRVAILLTEAG----IKTKDIAILTPYNAQVAKISESLHNNHIRDIT----VNTIMRSQGSEWRYVIMSTVRSCPKSEIETQPPKSWIMKRLGFITDPHQVNVGITRAQEGLCIIGNENLLRCSSLWRKLLNHYQEKGCVV 2638
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Zebrafish
Match: zgc:113057 (zgc:113057 [Source:ZFIN;Acc:ZDB-GENE-050508-3])

HSP 1 Score: 204.912 bits (520), Expect = 2.514e-52
Identity = 178/616 (28.90%), Postives = 292/616 (47.40%), Query Frame = 2 
Query: 3320 DIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKW-----ILG--KSIKTKKTERYGVITLSSDFC--NLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFD-LPKSAEN--VNFTLDIYQKSI-VSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNR------KEN---------KNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFK-------NKTLPIDIQEVSLHFLIRK-NGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLK-QVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGL 5056
            ++ L++ + + +++Q       GL     +L  V   F ICL H  NP+  F      D +    K S+ S +EY+  +  L + ++   AL + ++  LE+V I W     + G     KT+KT+      L++ F    LR     + + K  +R      S +S + G   CL          WV H  V T +K    N K + I F++T  +   +P    N    FT+++  K I   +R+Q + N      L+K V  G        +     +  ++  LN    N +Q  AVK A+ +  ++I GPPGTGKT+VG ++ F +   N+      K N         K   +LYCGPSN  +++VA  +++      P  LRI+  + E+ +FP  G   K       ++    ++++++L +L+RK    +++E+K  +                   + I  Y+ L+KKA +  I   K+D++LCT S  LK ++    +  Q++IDE  M  EPE  IP+   + + + +VL+GDH+Q+RP+++      +G++ SLFERY     +L  ML+ QYRMH  IC FPS EFY GKL T      C L
Sbjct:  761 ELNLELKLGDVVQVQLGSEFKDGLPVPVVQLLSVNECFEICLEHSRNPTLCFS-----DSVCIASKISYESYEEYQKIWTQLCQIDTAYNALEENNSVILEEVFINWSDEINLQGFFHLTKTQKTQWSLEFDLTNCFLCIRLRRQKLDENLGKHIDR------SAVSDLQG---CLPF-------TWVAHA-VTTKSKKKDANTKGR-INFKITHRSMTYIPARIFNKGTKFTIEVIPKKIPYLLREQAVANLKRANNLVKSVATGKLELNDDADLRNISLYDVDKSLNLPTLNMSQKKAVKEAMKKPFTVIQGPPGTGKTVVGIHIVFQFFKKNKDFMTSFKPNHTNPDGNPPKKPAILYCGPSNKSVDIVAEQLLKLSGVLKP--LRIYCDQMEMREFPYTGSELKLCRRSLRDEKPKEELRDITLMYLVRKPENPFSEEIKALEKNLSV--------------DQIDNYRKLLKKANQHEI--EKYDVVLCTCSSALKPELREVMDFRQILIDECAMATEPEAFIPL--VSHNPQQIVLLGDHQQIRPIVQCGHVKNKGMEKSLFERYM----DLANMLDTQYRMHAEICSFPSDEFYDGKLKTGAERGPCCL 1329

HSP 2 Score: 117.087 bits (292), Expect = 1.514e-25
Identity = 75/203 (36.95%), Postives = 110/203 (54.19%), Query Frame = 2 
Query: 5207 DAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDIN---YNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            D K     +R   C   + +E P  ++F  + G+E+S  V+T  GNE S  N  E E    +   L++      ++P  I +LT Y+ Q      E K  L KK   +  V TV++SQGSE  YVI STVRS +  DI      P   W  K LGF+T+ NQ+NVA+TRA+ GL I+GN  LL+  + W +L+++   ++CV+
Sbjct: 1315 DGKLKTGAERGPCCLLNKSKE-PTAMLFGHIEGKEVSLVVSTEKGNENSMANTEEAEQAVCVADLLIKQS---GVSPEHIAILTPYNAQVS----EIKMTLEKKNVRNVTVCTVMKSQGSEWPYVIVSTVRSCSTSDIQAYRVRPHKAWLGKRLGFVTDANQVNVAITRAQDGLCILGNSDLLRCCELWDRLLDHYYRKSCVV 1509

HSP 3 Score: 98.2117 bits (243), Expect = 8.646e-20
Identity = 99/403 (24.57%), Postives = 182/403 (45.16%), Query Frame = 2 
Query: 1652 SGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQ--SDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKE-YCNLLGVLNFNRN-----------------SRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPS--YYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEI 2794
            S    FTID+ +T+D+DDAIS     +   IG+HI+DV  Y+   SE  + A+    T Y P+  ++    +F  +++ ++LSL+ G+ R  +S+L      ++ DK  K S I   +F   +I S  +++Y+E    +++  S+      + L   +   Y+ +   R +RL   +       C   ++ + R +A  ++EE M L N   A    E+  ++ + +  +P++         H+  + N   Q KE Y +L+ +  +  N                 S   F +         EF +  D+     L+  DE        + D+  I   +    +C+ K+S  +GH+ L  + YT  +SP+RR+ D++V RLL +++ K  +       DEI
Sbjct:  224 SDIFTFTIDSTSTQDLDDAISVTEMDDSYQIGIHITDVASYIIKNSEQDEFARMLGRTIYTPEKGDVA--FMFSREISKEYLSLIDGEERRALSLL------VVVDK--KTSQIRSTQFALTLINSDRRMSYKEADQIIQKYFSETEPLRFSRLEDCVAVAYRFSEAHRKSRLEGGW------QCGRQVE-QTRSQA--MVEELMTLYNSAAA----EELISADVTKDLTPLR--------CHQGPDPNLLIQFKEKYTDLIPMSAYFSNMFDENMEYNPEHDGFEHSGMPFTIFTSILHKMEEFAQSRDYYSLTQLIFSDEIHPTLVPMVRDFREIKRKAVILRSCTSKES-RLGHYDLQMNAYTWASSPMRRYLDLIVQRLLHTMLSKQYLKQADYTNDEI 594
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Zebrafish
Match: upf1 (UPF1 RNA helicase and ATPase [Source:ZFIN;Acc:ZDB-GENE-040426-2836])

HSP 1 Score: 166.007 bits (419), Expect = 1.351e-40
Identity = 177/680 (26.03%), Postives = 281/680 (41.32%), Query Frame = 2 
Query: 3803 GDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PS    N+    + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD    + +  +    Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  +LL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  339 GDEICLR-YKGDMAPLWKGIGHVIKVPDNYGDEIAIEL------RSSAGAPVEVPH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPS----NIAVDQLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSMPELQKLQQL------KDET-GELSSSDE-KRYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRLKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTRLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 884
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Zebrafish
Match: upf1 (UPF1 RNA helicase and ATPase [Source:ZFIN;Acc:ZDB-GENE-040426-2836])

HSP 1 Score: 166.007 bits (419), Expect = 1.351e-40
Identity = 177/680 (26.03%), Postives = 281/680 (41.32%), Query Frame = 2 
Query: 3803 GDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PS    N+    + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD    + +  +    Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  +LL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  339 GDEICLR-YKGDMAPLWKGIGHVIKVPDNYGDEIAIEL------RSSAGAPVEVPH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPS----NIAVDQLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSMPELQKLQQL------KDET-GELSSSDE-KRYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRLKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTRLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 884
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Xenopus
Match: tbx21 (T-box 21 [Source:Xenbase;Acc:XB-GENE-479103])

HSP 1 Score: 187.193 bits (474), Expect = 6.513e-47
Identity = 223/944 (23.62%), Postives = 388/944 (41.10%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSD-IVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLP-YSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLL--RMQSPVKNR--EEWLENLHESTNLN--FAGQLKEYCNLLGVLNFNRN--SRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYH-ISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCS-EINDEEIICAHPL-LQVASSDNRIKFANLSLDEVPVLSKSNENF-GKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDF---CNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNY-WVGHGHVVTINKCMINNQKMKLIIFRLTQ-SNFDLPKSA--ENVNFTLDIYQKSIVSIRQQVIMNKI-DKIELLKEVILGAETNKKINNPTEKIIAQIENELNW------KKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNR-------KENKNS---VVLYCGPSNDCINLVASTMMEKFN 4378
            + FT+D +  KD+DDAIS         IGVHI+D+   + P  ++ ++A     T Y PK       H+    + T   SL P   R  +S LF   E        K +D +V     + VI S  +L+YEE +  L       +    +   L + +  ++  R  RL   + + +  + C    +     +A+++IEE M+L N +VA  +  K     L+  R Q+P   R  +E  +       L+   +  L E     G    +      Q+  V    ++   E   + D+D A+ LL  D+   E    + ++   +   S       D+   GH+SL    YT  +SP+RR+ D+VV RLL+ ++          D+D +C +   K     ++E+      +      R    L  V S +          P+     ++  ++++  L L + P      E   G   L WR+ ++    Y      +  +  I +  F +   Y             L   +L +    LCT       +   +    S      ++ L++   +T+ +Q C  +  G+    P+LF  TP  HICL H  +P   F SG    L H      + + +EY+  + PL   E+ M A+ + +A  L  V I+W            R G   L+      C L  D          N Y  L   G+     +         D + Y WV H   +T     +  +    + F L Q  N ++P++    + +FT+++  K +  IR++  ++++ +  EL K ++LG    K++   TE  I    NE N+      +  N +Q  AV++AL    +LI GPPGTGKT+VG ++ + +  +N+       +E +     +++YCGPSN  ++++A     K+ 
Sbjct:  336 LTFTVDPRDAKDLDDAISVQERDGHYEIGVHITDLASVIPPGGDLDREAMRRGVTFYSPKREAA---HMLPVPMCTARCSLKPLCERRALS-LFVLVE--------KETDWMVSGHLCQSVISSDRQLSYEEANAILADQGS-HSAFGSVEGCLAACWHFSQVHRAHRLQEAATYKQPDEKCPPGAR-----KAQMMIEEMMILYNSWVADFLTGKDSAMDLVPVRCQAPPTLRKIQELRDKFSHLLPLSSYLSHHLLEAPESPGPAPESPGLAPEQRITVFTPVWQQIEECAARGDYDGARDLLLTDDLHPELCHAVREFRRNLGRASTIRSGTADAT--GHYSLQLWAYTWASSPLRRYLDIVVQRLLQGILVGSVPPVAPKDMDFLCHHFERKVHQAASYERKGLAMELALALRGRGQQKLAVVVSVDAAGSSFQLVFPMNGDSLAAPMKVEYRYLQLAQQP------EGIPGGVRLSWRRRVYCYHTYREKPLGHKRRSDITT--FSARAWYD-----------ALYALSLSDPGQALCTLHKGVEVAEDGAEVQQSSCGHHTNLTLELKPGDTLPVQLCSAQERGIPMPRPQLFSPTPGIHICLEHSESPVDCF-SG----LAHRAPLRCYGNAQEYQAVWGPLCAMEAAMSAVGEGNAVVLRNVPIRW--HNKDTGGGPARKGSFKLTPPLIADCELDMDFQ--------NCYLCLRMEGLQGAQAE------SPLDSHLYTWVAH--CLTDPSNHVTEEHGGAVTFHLHQRPNQEIPEAVLHSDNSFTVELIPKLLPDIRKEAALDQMKEASELAKNIVLG----KRV---TETDITTFRNERNFDIPALGRGLNPSQREAVQSALRGPFTLIQGPPGTGKTVVGVHIIYWFHQMNQGAVPPCAQEGEGPDRKLLMYCGPSNKSVDVLAGKGGAKWG 1210
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Xenopus
Match: UPF1 (UPF1 regulator of nonsense transcripts homolog [Source:NCBI gene;Acc:100135270])

HSP 1 Score: 167.933 bits (424), Expect = 4.123e-41
Identity = 194/771 (25.16%), Postives = 311/771 (40.34%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL     ++R                         + GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PS    N+    + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  282 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAYFTLPKTDSDMRL------------------------MQGDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPS----NIAVDQLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMESMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 885
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Xenopus
Match: UPF1 (UPF1 regulator of nonsense transcripts homolog [Source:NCBI gene;Acc:100135270])

HSP 1 Score: 167.933 bits (424), Expect = 4.193e-41
Identity = 194/771 (25.16%), Postives = 311/771 (40.34%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL     ++R                         + GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PS    N+    + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  308 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAYFTLPKTDSDMRL------------------------MQGDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPS----NIAVDQLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMESMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 911
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Xenopus
Match: UPF1 (UPF1 regulator of nonsense transcripts homolog [Source:NCBI gene;Acc:100135270])

HSP 1 Score: 167.933 bits (424), Expect = 4.409e-41
Identity = 194/771 (25.16%), Postives = 311/771 (40.34%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL     ++R                         + GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PS    N+    + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  294 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAYFTLPKTDSDMRL------------------------MQGDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPS----NIAVDQLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMESMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 897
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Xenopus
Match: UPF1 (UPF1 regulator of nonsense transcripts homolog [Source:NCBI gene;Acc:100135270])

HSP 1 Score: 167.933 bits (424), Expect = 4.818e-41
Identity = 194/771 (25.16%), Postives = 312/771 (40.47%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL     ++R                         + GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PSN  ++     + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  287 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAYFTLPKTDSDMRL------------------------MQGDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPSNIAVD----QLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMESMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 890
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Mouse
Match: Helz2 (helicase with zinc finger 2, transcriptional coactivator [Source:MGI Symbol;Acc:MGI:2385169])

HSP 1 Score: 206.068 bits (523), Expect = 1.995e-52
Identity = 117/315 (37.14%), Postives = 179/315 (56.83%), Query Frame = 2 
Query: 4154 KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNS------------VVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTL----------PIDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLIT 5029
            K N++Q  AV++AL ++ ++I GPPGTGKT+VG ++ + +   N+++                 VLYCGPSN  ++++   ++ +  E  P  LR++G++ E ++FP+PG    N++L             ++ ++LH  IR+    YA E++KFD   +    K     D  VY  +L       KA+K  +   +  +ILCT S    + +   N+ Q++IDEAGM  EPETLIP+   +K+V+ VVL+GDHKQLRP+++S      G+  SLFERY +       ML+ QYRMH  IC FPS+EFY GKL T
Sbjct: 2448 KLNQSQDRAVRSALQKQFTVIQGPPGTGKTVVGFHIVYWFHRSNQEQMPTDSSPSGEEQLGGPCVLYCGPSNKSVDVLGGLLLRRKTEMKP--LRVYGEQAEATEFPLPG--VSNRSLFGKTSQEGRPNQSLRSITLHHRIRQAPNPYAAEIRKFDAQLR--EGKIFSKEDLRVYRRVL------GKARKHEL--ERHSVILCTCSCAASKSLKILNVRQILIDEAGMATEPETLIPLVCFSKTVEKVVLLGDHKQLRPVVKSEQLQSLGMDRSLFERYHR----DAIMLDTQYRMHKDICSFPSVEFYGGKLKT 2744

HSP 2 Score: 105.531 bits (262), Expect = 7.941e-22
Identity = 64/176 (36.36%), Postives = 98/176 (55.68%), Query Frame = 2 
Query: 5282 IIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIA 5809
            +IF  V G E    V+T  GNE S+ N  EV  V  I K+L        + P  I VLT Y+ Q   +       L+++  T   V ++ +SQGSE  YVI STVR+    D++  PT  W +K LGF+ + +Q+NVA+TRA++ L IIG+  LL+    W +L++  E ++ +++
Sbjct: 2765 VIFGSVQGHEQKLLVSTEDGNENSRANPEEVTQVVRIIKQL---TLDRTVDPKDIAVLTPYNAQAAAISRG----LMQRGVTGVTVTSITKSQGSEWRYVIVSTVRTCPRSDVDQRPTKSWLKKFLGFVVDPHQVNVAITRAQEALCIIGDHLLLRCCPLWHRLLDFCEAQHSLVS 2933

HSP 3 Score: 77.7962 bits (190), Expect = 1.624e-13
Identity = 95/415 (22.89%), Postives = 177/415 (42.65%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYHREMNQIV-IGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQS-----DDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRF----EAELLIEEFMLLANEYVARIIYEKYPNSTL--LRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGV-LNFNRNSRQKFIVSRKFFELFNEFIKQ-------SDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMG-HFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEK 2842
            + FT+D +   ++DDA+S  R++  +  + VHI+DV   V     +  +A+      Y P   N  P  +    L  D LSL+PG+ R  +S+     +     K+ +F+          +I S  +L+YEE    +K+      + PA++D+     + + Y  +  +R  RL  +        CY     E+       A ++++E+M+  N +VA  +       TL  LR Q P  +R++ L+++            K+Y  L+ + L+   +S   +  +++   L     KQ        D+ +   L+  D+          D       S +  S +       H SL    YT  TSPIRR+ DVV+ RL+   +        + DID +C++ + +    +++++
Sbjct: 1574 LTFTVDPQGACNLDDALSV-RDLGPVYEVAVHIADVASLVPKDGALDVEARQQGTVFYAP---NREPVLMLPASLCQDALSLLPGQDRLAISLFLTMEKGGGQIKSLRFA--------PSIIRSDRQLSYEEAEELIKRHPGAGLELPAHLDSVEACVVAACY-FSWMLRRQRLSAA--------CYYEPPDEDSVLGFRTAHIMVQEYMIQFNSHVAEFLVSNKHTQTLTPLRWQ-PTPSRQQ-LDSV-----------FKKYRGLVPLSLHLCHHSNTDYTPNKQ-LHLLTSLWKQVQLAAGTQDYSQMVDLIAADDMHPSLAPACLDLRRALGRSVFGRSSQGKQQPAVHHSLQVDWYTWATSPIRRYLDVVLQRLILLALGHRGSTYSNRDIDGLCLDFSRQYASAQSYQR 1953

HSP 4 Score: 52.7582 bits (125), Expect = 7.571e-6
Identity = 57/203 (28.08%), Postives = 86/203 (42.36%), Query Frame = 2 
Query: 4682 MILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRG---LQISLFERYQ----KLKPELVTMLNLQYRMHPSICDFPSMEFY---------SGKLITHVS--PLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKR 5236
            +++ TTS   +  V     + + IDEA    E E LIP++ A  S+  VVL GDH Q+ P + S   DK     L   LF  YQ    K+  +   + +  YR   +I +F S  FY         SGK+  H    PL          +FCH + S ++   +    N  +  + V+  +E      YN  P   W  + +R
Sbjct:  889 LVVTTTSQARELQVPAGFFSHIFIDEAAQMLECEALIPLSYAL-SLTRVVLAGDHMQVTPRLFSVPRDKSARHTLLHRLFLYYQQEAHKIAQQSRIIFHENYRSTAAIINFVSHHFYLAKGNPIQASGKVPRHPQHYPL----------MFCHVAGSPEQDMSMTSWLNSAEVTQVVEKVREI-----YNTWPHC-WGPREQR 1074
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Mouse
Match: Helz2 (helicase with zinc finger 2, transcriptional coactivator [Source:MGI Symbol;Acc:MGI:2385169])

HSP 1 Score: 206.068 bits (523), Expect = 2.002e-52
Identity = 117/315 (37.14%), Postives = 179/315 (56.83%), Query Frame = 2 
Query: 4154 KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNS------------VVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTL----------PIDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLIT 5029
            K N++Q  AV++AL ++ ++I GPPGTGKT+VG ++ + +   N+++                 VLYCGPSN  ++++   ++ +  E  P  LR++G++ E ++FP+PG    N++L             ++ ++LH  IR+    YA E++KFD   +    K     D  VY  +L       KA+K  +   +  +ILCT S    + +   N+ Q++IDEAGM  EPETLIP+   +K+V+ VVL+GDHKQLRP+++S      G+  SLFERY +       ML+ QYRMH  IC FPS+EFY GKL T
Sbjct: 2448 KLNQSQDRAVRSALQKQFTVIQGPPGTGKTVVGFHIVYWFHRSNQEQMPTDSSPSGEEQLGGPCVLYCGPSNKSVDVLGGLLLRRKTEMKP--LRVYGEQAEATEFPLPG--VSNRSLFGKTSQEGRPNQSLRSITLHHRIRQAPNPYAAEIRKFDAQLR--EGKIFSKEDLRVYRRVL------GKARKHEL--ERHSVILCTCSCAASKSLKILNVRQILIDEAGMATEPETLIPLVCFSKTVEKVVLLGDHKQLRPVVKSEQLQSLGMDRSLFERYHR----DAIMLDTQYRMHKDICSFPSVEFYGGKLKT 2744

HSP 2 Score: 105.531 bits (262), Expect = 7.953e-22
Identity = 64/176 (36.36%), Postives = 98/176 (55.68%), Query Frame = 2 
Query: 5282 IIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIA 5809
            +IF  V G E    V+T  GNE S+ N  EV  V  I K+L        + P  I VLT Y+ Q   +       L+++  T   V ++ +SQGSE  YVI STVR+    D++  PT  W +K LGF+ + +Q+NVA+TRA++ L IIG+  LL+    W +L++  E ++ +++
Sbjct: 2765 VIFGSVQGHEQKLLVSTEDGNENSRANPEEVTQVVRIIKQL---TLDRTVDPKDIAVLTPYNAQAAAISRG----LMQRGVTGVTVTSITKSQGSEWRYVIVSTVRTCPRSDVDQRPTKSWLKKFLGFVVDPHQVNVAITRAQEALCIIGDHLLLRCCPLWHRLLDFCEAQHSLVS 2933

HSP 3 Score: 77.7962 bits (190), Expect = 1.626e-13
Identity = 95/415 (22.89%), Postives = 177/415 (42.65%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYHREMNQIV-IGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQS-----DDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRF----EAELLIEEFMLLANEYVARIIYEKYPNSTL--LRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGV-LNFNRNSRQKFIVSRKFFELFNEFIKQ-------SDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMG-HFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEK 2842
            + FT+D +   ++DDA+S  R++  +  + VHI+DV   V     +  +A+      Y P   N  P  +    L  D LSL+PG+ R  +S+     +     K+ +F+          +I S  +L+YEE    +K+      + PA++D+     + + Y  +  +R  RL  +        CY     E+       A ++++E+M+  N +VA  +       TL  LR Q P  +R++ L+++            K+Y  L+ + L+   +S   +  +++   L     KQ        D+ +   L+  D+          D       S +  S +       H SL    YT  TSPIRR+ DVV+ RL+   +        + DID +C++ + +    +++++
Sbjct: 1574 LTFTVDPQGACNLDDALSV-RDLGPVYEVAVHIADVASLVPKDGALDVEARQQGTVFYAP---NREPVLMLPASLCQDALSLLPGQDRLAISLFLTMEKGGGQIKSLRFA--------PSIIRSDRQLSYEEAEELIKRHPGAGLELPAHLDSVEACVVAACY-FSWMLRRQRLSAA--------CYYEPPDEDSVLGFRTAHIMVQEYMIQFNSHVAEFLVSNKHTQTLTPLRWQ-PTPSRQQ-LDSV-----------FKKYRGLVPLSLHLCHHSNTDYTPNKQ-LHLLTSLWKQVQLAAGTQDYSQMVDLIAADDMHPSLAPACLDLRRALGRSVFGRSSQGKQQPAVHHSLQVDWYTWATSPIRRYLDVVLQRLILLALGHRGSTYSNRDIDGLCLDFSRQYASAQSYQR 1953

HSP 4 Score: 52.7582 bits (125), Expect = 7.575e-6
Identity = 57/203 (28.08%), Postives = 86/203 (42.36%), Query Frame = 2 
Query: 4682 MILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRG---LQISLFERYQ----KLKPELVTMLNLQYRMHPSICDFPSMEFY---------SGKLITHVS--PLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKR 5236
            +++ TTS   +  V     + + IDEA    E E LIP++ A  S+  VVL GDH Q+ P + S   DK     L   LF  YQ    K+  +   + +  YR   +I +F S  FY         SGK+  H    PL          +FCH + S ++   +    N  +  + V+  +E      YN  P   W  + +R
Sbjct:  889 LVVTTTSQARELQVPAGFFSHIFIDEAAQMLECEALIPLSYAL-SLTRVVLAGDHMQVTPRLFSVPRDKSARHTLLHRLFLYYQQEAHKIAQQSRIIFHENYRSTAAIINFVSHHFYLAKGNPIQASGKVPRHPQHYPL----------MFCHVAGSPEQDMSMTSWLNSAEVTQVVEKVREI-----YNTWPHC-WGPREQR 1074
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Mouse
Match: Helz2 (helicase with zinc finger 2, transcriptional coactivator [Source:MGI Symbol;Acc:MGI:2385169])

HSP 1 Score: 181.03 bits (458), Expect = 8.047e-45
Identity = 106/290 (36.55%), Postives = 160/290 (55.17%), Query Frame = 2 
Query: 4229 GTGKTMVGCYLSFAYTFVNRKENKNS------------VVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTL----------PIDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLIT 5029
            GTGKT+VG ++ + +   N+++                 VLYCGPSN  ++++   ++ +  E  P  LR++G++ E ++FP+PG    N++L             ++ ++LH  IR+    YA E++KFD   +    K     D  VY  +L       KA+K  +   +  +ILCT S    + +   N+ Q++IDEAGM  EPETLIP+   +K+V+ VVL+GDHKQLRP+++S      G+  SLFERY +       ML+ QYRMH  IC FPS+EFY GKL T
Sbjct: 2429 GTGKTVVGFHIVYWFHRSNQEQMPTDSSPSGEEQLGGPCVLYCGPSNKSVDVLGGLLLRRKTEMKP--LRVYGEQAEATEFPLPG--VSNRSLFGKTSQEGRPNQSLRSITLHHRIRQAPNPYAAEIRKFDAQLR--EGKIFSKEDLRVYRRVL------GKARKHEL--ERHSVILCTCSCAASKSLKILNVRQILIDEAGMATEPETLIPLVCFSKTVEKVVLLGDHKQLRPVVKSEQLQSLGMDRSLFERYHR----DAIMLDTQYRMHKDICSFPSVEFYGGKLKT 2700

HSP 2 Score: 105.531 bits (262), Expect = 7.919e-22
Identity = 64/176 (36.36%), Postives = 98/176 (55.68%), Query Frame = 2 
Query: 5282 IIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIA 5809
            +IF  V G E    V+T  GNE S+ N  EV  V  I K+L        + P  I VLT Y+ Q   +       L+++  T   V ++ +SQGSE  YVI STVR+    D++  PT  W +K LGF+ + +Q+NVA+TRA++ L IIG+  LL+    W +L++  E ++ +++
Sbjct: 2721 VIFGSVQGHEQKLLVSTEDGNENSRANPEEVTQVVRIIKQL---TLDRTVDPKDIAVLTPYNAQAAAISRG----LMQRGVTGVTVTSITKSQGSEWRYVIVSTVRTCPRSDVDQRPTKSWLKKFLGFVVDPHQVNVAITRAQEALCIIGDHLLLRCCPLWHRLLDFCEAQHSLVS 2889

HSP 3 Score: 77.7962 bits (190), Expect = 1.621e-13
Identity = 95/415 (22.89%), Postives = 177/415 (42.65%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYHREMNQIV-IGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQS-----DDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRF----EAELLIEEFMLLANEYVARIIYEKYPNSTL--LRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGV-LNFNRNSRQKFIVSRKFFELFNEFIKQ-------SDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMG-HFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEK 2842
            + FT+D +   ++DDA+S  R++  +  + VHI+DV   V     +  +A+      Y P   N  P  +    L  D LSL+PG+ R  +S+     +     K+ +F+          +I S  +L+YEE    +K+      + PA++D+     + + Y  +  +R  RL  +        CY     E+       A ++++E+M+  N +VA  +       TL  LR Q P  +R++ L+++            K+Y  L+ + L+   +S   +  +++   L     KQ        D+ +   L+  D+          D       S +  S +       H SL    YT  TSPIRR+ DVV+ RL+   +        + DID +C++ + +    +++++
Sbjct: 1574 LTFTVDPQGACNLDDALSV-RDLGPVYEVAVHIADVASLVPKDGALDVEARQQGTVFYAP---NREPVLMLPASLCQDALSLLPGQDRLAISLFLTMEKGGGQIKSLRFA--------PSIIRSDRQLSYEEAEELIKRHPGAGLELPAHLDSVEACVVAACY-FSWMLRRQRLSAA--------CYYEPPDEDSVLGFRTAHIMVQEYMIQFNSHVAEFLVSNKHTQTLTPLRWQ-PTPSRQQ-LDSV-----------FKKYRGLVPLSLHLCHHSNTDYTPNKQ-LHLLTSLWKQVQLAAGTQDYSQMVDLIAADDMHPSLAPACLDLRRALGRSVFGRSSQGKQQPAVHHSLQVDWYTWATSPIRRYLDVVLQRLILLALGHRGSTYSNRDIDGLCLDFSRQYASAQSYQR 1953

HSP 4 Score: 52.7582 bits (125), Expect = 7.562e-6
Identity = 57/203 (28.08%), Postives = 86/203 (42.36%), Query Frame = 2 
Query: 4682 MILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRG---LQISLFERYQ----KLKPELVTMLNLQYRMHPSICDFPSMEFY---------SGKLITHVS--PLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKR 5236
            +++ TTS   +  V     + + IDEA    E E LIP++ A  S+  VVL GDH Q+ P + S   DK     L   LF  YQ    K+  +   + +  YR   +I +F S  FY         SGK+  H    PL          +FCH + S ++   +    N  +  + V+  +E      YN  P   W  + +R
Sbjct:  889 LVVTTTSQARELQVPAGFFSHIFIDEAAQMLECEALIPLSYAL-SLTRVVLAGDHMQVTPRLFSVPRDKSARHTLLHRLFLYYQQEAHKIAQQSRIIFHENYRSTAAIINFVSHHFYLAKGNPIQASGKVPRHPQHYPL----------MFCHVAGSPEQDMSMTSWLNSAEVTQVVEKVREI-----YNTWPHC-WGPREQR 1074
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Mouse
Match: Upf1 (UPF1 regulator of nonsense transcripts homolog (yeast) [Source:MGI Symbol;Acc:MGI:107995])

HSP 1 Score: 174.096 bits (440), Expect = 4.457e-43
Identity = 196/771 (25.42%), Postives = 320/771 (41.50%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL       ++D  ++++  I+ R   L+        GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E ++ + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PSN  ++     + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  296 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAFFTLP------KTDSGNEDLVIIWLRDMRLMQ-------GDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVVIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPSNIAVD----QLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPI-RLQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLSYYKEQKALVEGPLN 910
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Mouse
Match: Upf1 (UPF1 regulator of nonsense transcripts homolog (yeast) [Source:MGI Symbol;Acc:MGI:107995])

HSP 1 Score: 169.088 bits (427), Expect = 1.616e-41
Identity = 193/771 (25.03%), Postives = 312/771 (40.47%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL     ++R                         + GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E ++ + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PSN  ++     + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  296 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAFFTLPKTDSDMRL------------------------MQGDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVVIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPSNIAVD----QLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPI-RLQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLSYYKEQKALVEGPLN 899
[Close]
BLAST of Helicase with zinc finger domain 2 vs. UniProt/SwissProt
Match: sp|Q9BYK8|HELZ2_HUMAN (Helicase with zinc finger domain 2 OS=Homo sapiens OX=9606 GN=HELZ2 PE=1 SV=6)

HSP 1 Score: 345.895 bits (886), Expect = 2.650e-94
Identity = 351/1448 (24.24%), Postives = 615/1448 (42.47%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDD-----PANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYH-ISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDN-----RIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSC----PPY-LNSSSSNDNKFKIDSHLFDSYLPYSD-------SKLFQEIRRSYLSGEALENK-LNQL----CTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLR-SDIFHKEIYKIFNRYEYLIAS------GISSVGGDLLCLRCRKEDWNNY-WVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVN-----FTLDIYQKSIVSIRQQVIMNKIDKIE-LLKEVILGAETNKKINN--PTEKIIAQIENELNWK-KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENK------------NSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIP--GHFFKNKTLPID------IQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            + FT+D +   ++DDA+S      +  + VHI+DV  +V     +  +A+      Y P    +P   +    L  D LSL+PG+ R  +S+     +     K+ +F+          V+ S  +L+YEE    ++Q        PA +D+     + + Y      RH      ++ +  ++     +      A ++++E+M+  N  VA  +       T+  ++     R + L+ L E         L    +L G      ++R   + S   ++      +  D+++   L+  D+          D    +   ++  C+       GH+SL    YT  TSPIRR+ DVV+ R +   +        + DID +C   + +    +++++      +  +   +    LD +   ++ E       LL  ++ +       + + +L L E P             L WR+ ++S     PP  L  +  + +   +++ L+   L   +       + L QE       GEA + + L Q+    C  F                    +++  ++   +T+++Q       G +  +P+L+ V P F +CL H   P   F SG     ++   ++ +  + EY   +EP    ES   A+++  + TL+ + + W   ++ +T + +  G   L + F     +DI     Y +  R E L A       G SS+G  L        D   Y WV HG     ++    +++       L   +  + K  E V      FT+++  K +  +R++  +  +++   L+  + LG    + +    P+  +  Q  N    + K N +Q  AV+ AL +  ++I GPPGTGKT+VG ++ F +   N+++ +               +LYCGPSN  ++++A  ++ +   K    LR++ ++ E S+FP+P  G     +  P +      ++ ++LH  IR+    Y+ E+K FD   +  R       +      ++ YK ++ +A+K  +  ++ ++ILCT S      +   ++ Q+++DEAGM  EPETLIP+    ++ K VVL+GDHKQLRP++++      GL  SLFERY     E   ML+ QYRMH                                                     GI    SV  YK  LKT          W G R+ P    H   E  P  +IF  V G E S  V+T  GNE SK N  EV  V  I K+L        + P  I VLT Y+ Q      E    L ++      V ++ +SQGSE  YV+ STVR+    D++  PT  W +K LGF+ + NQ+NVA+TRA++GL +IG+  LL+    W+ L++  E +  ++
Sbjct: 1341 LTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVP---MLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAP--------SVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRA-----AHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLAS--LWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQ---PLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGL---RLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQE------KGEASQRRELVQVQRSHCGHF--------------------LEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCF-SG----RVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSW---EASRTPQGQLQGAFRLEAAFLEENCADINFSCCY-LCIRLEGLPAPTASPRPGPSSLGPGL------NVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELK---PLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQ--RG------ELFSREDLVWYKKVLWEARKFEL--DRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEK-VVLLGDHKQLRPVVKNERLQNLGLDRSLFERYH----EDAHMLDTQYRMH----------------------------------------------------EGICAFPSVAFYKSKLKT----------WQGLRRPPSVLGHAGKESCP--VIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQL---TLGRTVEPQDIAVLTPYNAQAS----EISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2634
[Close]
BLAST of Helicase with zinc finger domain 2 vs. UniProt/SwissProt
Match: sp|E9QAM5|HELZ2_MOUSE (Helicase with zinc finger domain 2 OS=Mus musculus OX=10090 GN=Helz2 PE=1 SV=1)

HSP 1 Score: 206.068 bits (523), Expect = 1.396e-51
Identity = 117/315 (37.14%), Postives = 179/315 (56.83%), Query Frame = 2 
Query: 4154 KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNS------------VVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTL----------PIDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLIT 5029
            K N++Q  AV++AL ++ ++I GPPGTGKT+VG ++ + +   N+++                 VLYCGPSN  ++++   ++ +  E  P  LR++G++ E ++FP+PG    N++L             ++ ++LH  IR+    YA E++KFD   +    K     D  VY  +L       KA+K  +   +  +ILCT S    + +   N+ Q++IDEAGM  EPETLIP+   +K+V+ VVL+GDHKQLRP+++S      G+  SLFERY +       ML+ QYRMH  IC FPS+EFY GKL T
Sbjct: 2448 KLNQSQDRAVRSALQKQFTVIQGPPGTGKTVVGFHIVYWFHRSNQEQMPTDSSPSGEEQLGGPCVLYCGPSNKSVDVLGGLLLRRKTEMKP--LRVYGEQAEATEFPLPG--VSNRSLFGKTSQEGRPNQSLRSITLHHRIRQAPNPYAAEIRKFDAQLR--EGKIFSKEDLRVYRRVL------GKARKHEL--ERHSVILCTCSCAASKSLKILNVRQILIDEAGMATEPETLIPLVCFSKTVEKVVLLGDHKQLRPVVKSEQLQSLGMDRSLFERYHR----DAIMLDTQYRMHKDICSFPSVEFYGGKLKT 2744

HSP 2 Score: 105.531 bits (262), Expect = 5.555e-21
Identity = 64/176 (36.36%), Postives = 98/176 (55.68%), Query Frame = 2 
Query: 5282 IIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIA 5809
            +IF  V G E    V+T  GNE S+ N  EV  V  I K+L        + P  I VLT Y+ Q   +       L+++  T   V ++ +SQGSE  YVI STVR+    D++  PT  W +K LGF+ + +Q+NVA+TRA++ L IIG+  LL+    W +L++  E ++ +++
Sbjct: 2765 VIFGSVQGHEQKLLVSTEDGNENSRANPEEVTQVVRIIKQL---TLDRTVDPKDIAVLTPYNAQAAAISRG----LMQRGVTGVTVTSITKSQGSEWRYVIVSTVRTCPRSDVDQRPTKSWLKKFLGFVVDPHQVNVAITRAQEALCIIGDHLLLRCCPLWHRLLDFCEAQHSLVS 2933

HSP 3 Score: 77.7962 bits (190), Expect = 1.136e-12
Identity = 95/415 (22.89%), Postives = 177/415 (42.65%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYHREMNQIV-IGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQS-----DDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRF----EAELLIEEFMLLANEYVARIIYEKYPNSTL--LRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGV-LNFNRNSRQKFIVSRKFFELFNEFIKQ-------SDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMG-HFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEK 2842
            + FT+D +   ++DDA+S  R++  +  + VHI+DV   V     +  +A+      Y P   N  P  +    L  D LSL+PG+ R  +S+     +     K+ +F+          +I S  +L+YEE    +K+      + PA++D+     + + Y  +  +R  RL  +        CY     E+       A ++++E+M+  N +VA  +       TL  LR Q P  +R++ L+++            K+Y  L+ + L+   +S   +  +++   L     KQ        D+ +   L+  D+          D       S +  S +       H SL    YT  TSPIRR+ DVV+ RL+   +        + DID +C++ + +    +++++
Sbjct: 1574 LTFTVDPQGACNLDDALSV-RDLGPVYEVAVHIADVASLVPKDGALDVEARQQGTVFYAP---NREPVLMLPASLCQDALSLLPGQDRLAISLFLTMEKGGGQIKSLRFA--------PSIIRSDRQLSYEEAEELIKRHPGAGLELPAHLDSVEACVVAACY-FSWMLRRQRLSAA--------CYYEPPDEDSVLGFRTAHIMVQEYMIQFNSHVAEFLVSNKHTQTLTPLRWQ-PTPSRQQ-LDSV-----------FKKYRGLVPLSLHLCHHSNTDYTPNKQ-LHLLTSLWKQVQLAAGTQDYSQMVDLIAADDMHPSLAPACLDLRRALGRSVFGRSSQGKQQPAVHHSLQVDWYTWATSPIRRYLDVVLQRLILLALGHRGSTYSNRDIDGLCLDFSRQYASAQSYQR 1953
[Close]
BLAST of Helicase with zinc finger domain 2 vs. UniProt/SwissProt
Match: sp|Q9EPU0|RENT1_MOUSE (Regulator of nonsense transcripts 1 OS=Mus musculus OX=10090 GN=Upf1 PE=1 SV=2)

HSP 1 Score: 174.096 bits (440), Expect = 3.117e-42
Identity = 196/771 (25.42%), Postives = 320/771 (41.50%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL       ++D  ++++  I+ R   L+        GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E ++ + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PSN  ++     + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  296 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAFFTLP------KTDSGNEDLVIIWLRDMRLMQ-------GDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVVIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPSNIAVD----QLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPI-RLQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLSYYKEQKALVEGPLN 910
[Close]
BLAST of Helicase with zinc finger domain 2 vs. UniProt/SwissProt
Match: sp|Q92900|RENT1_HUMAN (Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2)

HSP 1 Score: 172.94 bits (437), Expect = 6.750e-42
Identity = 197/771 (25.55%), Postives = 319/771 (41.37%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL       ++D  ++++  I+ R   L+        GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PS    N+    + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  KLL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  301 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAYFTLP------KTDSGNEDLVIIWLRDMRLMQ-------GDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEVTH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPS----NIAVDQLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSMPELQKLQQL------KDETGELSSADEK--RYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPI-RLQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRVKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTKLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 915
[Close]
BLAST of Helicase with zinc finger domain 2 vs. UniProt/SwissProt
Match: sp|P30771|NAM7_YEAST (ATP-dependent helicase NAM7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=NAM7 PE=1 SV=1)

HSP 1 Score: 169.088 bits (427), Expect = 8.142e-41
Identity = 167/568 (29.40%), Postives = 250/568 (44.01%), Query Frame = 2 
Query: 4145 NWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILT--YKNLVKKAKKEYIVKNKFDMILCT-TSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPER---IIFIDVIG-EEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQH--LLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            N+ + N +Q NAV + L + LSLI GPPGTGKT+    + +  + +++       +L C PSN  ++ +A+    K  +   K++R+  K +E               +   +  ++LH L+ +  G   ELK   N+ K    KD +       +A  T  +  LV+K + E +  NK D++ CT      K++ T F    V+IDE+    EPE LIPI    K  K V+L+GDH+QL P+I  R A   GL+ SLFER   L   +   L +QYRM+P + +FPS  FY G L                                    NG+  E+                +P++K+P                +P R   ++F    G EEIS        N  S  N++E      I  KL    F   + P  I V+T Y  Q+   L  M+    L K       V +V   QG E DY+I S VR+              EQ+ +GF+ +  ++NV LTRAK GL+I+GN R L  N  W  L+ +  E+ C++   L+
Sbjct:  405 NFAQLNSSQSNAVSHVLQRPLSLIQGPPGTGKTVTSATIVYHLSKIHKDR-----ILVCAPSNVAVDHLAA----KLRDLGLKVVRLTAKSRE--------------DVESSVSNLALHNLVGR--GAKGELK---NLLKL---KDEV----GELSASDTKRFVKLVRKTEAEIL--NKADVVCCTCVGAGDKRLDTKFRT--VLIDESTQASEPECLIPI---VKGAKQVILVGDHQQLGPVILERKAADAGLKQSLFERLISLG-HVPIRLEVQYRMNPYLSEFPSNMFYEGSL-----------------------------------QNGVTIEQ--------------RTVPNSKFP----------------WPIRGIPMMFWANYGREEIS-------ANGTSFLNRIEAMNCERIITKL----FRDGVKPEQIGVITPYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAFQGREKDYIILSCVRAN-------------EQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSLARNTLWNHLLIHFREKGCLVEGTLD 840
[Close]
BLAST of Helicase with zinc finger domain 2 vs. TrEMBL
Match: A0A210QEW8 (Helicase with zinc finger domain 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT08385 PE=4 SV=1)

HSP 1 Score: 489.189 bits (1258), Expect = 1.910e-137
Identity = 458/1677 (27.31%), Postives = 757/1677 (45.14%), Query Frame = 2 
Query: 1079 GKVMG--VYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYE--------KEVKTI-----REKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIV-IGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSEN--MINDKNFKFSDIVQPEFREDVIISKYKLNYEEVS-LWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENR----FEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQS--PVKNREEWLENLHESTN--LNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKF-FELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNC--SEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEP--YAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNR-IKFANLSLDEVPVLSKSNEN---FGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSH---LFDSYLPY---------SDSKLFQE---IRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIF----------NRYEYLIASGISSVGGDLLCLRCRKE-------------DWNNYWVGHGHVVTINKCMINNQKMKLI--IFRLTQSNFDLP----KSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIENELNWKKFNRN---QYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNR----KENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPI------DIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVY----NAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVV---TFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            GKV+G    + F    + + VC + + + +LM PLDK+ PK+H+ N    N ++ ++ +                   +S + +  FS  ++  IN                      Y+F+V++ +W+   +YP G ++  + S   +            L +LE+  +          + V++I      E   IL +  I       VFTID K +KD+DD +S  R  + +  +GVHI+DVT YV     + ++AK    T YP      PPYH+  E L+ +  SL+P K +  +SV   FS +  +I  +            ++ V+ S+ + +Y++V  + L  + D     +D+      +++IA+ +R  RL  S     ++    N +   R     EA  L+EEFM+LAN   A ++   + +  LLR Q+  P +   +WL +     +  L            L + N  +   +  I  +K+ +    + +K  ++  A  L+  DE+  E  +   +W      + Y C  S K+     HF+LN S YTHFTSPIRR+ D+V HRL+ + ++K ++     +I++IC + N  S+  K + K C    Y  V   N     + +     ++D+ I    P +Q    + R ++   L +   P + K  ++   F    L W+K ++S   Y  S+   +N  ++D H   +F  YL +          D+KL ++   +   Y  G+ L++ +   CT                +  +   +  +       + +Q       G++   P++  +T +F +CL H ++P K+               E++ SI EY + +  LI  E+   A  D  A T+  + +K            E+ G  +++ DFC  R+  F     +            +  +Y+ +S       D LCL+CR E                  W+ HG V  I K     +KM  I   F L  S+  LP     S      +++I  K   + R +  +  +DK   L + I        ++     +  ++E E++     RN   QY A++ AL  + +LI GPPGTGKT  G  L + +T +NR    + N    V+YCGPSN  ++LVA    +K  E  P+++R++G   E  DFPIPG  + +K+         D+Q+++LH LIR+ G  +ADE+ +FD  F+   N  P   D ++     N +  Y +L+ KA +E +    +D+I CTT++T        T   I Q IIDE GMC EPE+L  I A     + VVLIGDHKQLRP++  + A + GL+ SLFERY     E    L+ QYR                     ++P  C   S                                + Y + L T+     P   W  K + P   +  ++ + P   IF  V GEE   +V+T  GNE S  NK EVE V  +++++L+T     + P +I +++QY+ Q H +    K+ L+     +  V TV+ SQG E DYVIFST RS+    I   PT GW +++LGFIT+ +QI+VAL+RA+KGL+IIGN+ LL+ ++ WK L+++  +R CV+
Sbjct:  717 GKVVGRLSRKRFRDIEHPVLVCGLDELEYHLMRPLDKTVPKLHIFNKHVENNFQVEVYD------------------YDSCSCDLKFS--NVVNINPAQKH----------------SYVFLVVFIRWDA--VYPLGAVIKVMRSDGGINS---------GLKILELQHQVPTTYNHDTIQSVQSIMSTMPEEPAPILTEDRIDFSESLSVFTIDPKDSKDLDDGLSIQRLSDNVYEVGVHIADVTSYVHKGDAIDEEAKSRATTFYPGHAK--PPYHMLPEPLSQNLCSLLPNKKKLALSVFLYFSADGELIRQRT---------SIKQTVVKSRRQFSYQDVQDIILDSTVDDETTSSDII----DLFRIAKGLRWRRLGESMHSFPIEVDLLNGRESERMFDTLEAHFLVEEFMILANMTAASLVSSSFRDCALLRCQNAPPPEKVNQWLNDYPRIADVILKLQNIKPTPQRQLKIANAPKARYRVVIELQKWIWSCLEQHVKDGNYRDACKLIGSDEFHPEQAIAWNEWICFQEHAEYRCLGSMKNRKERFHFTLNISPYTHFTSPIRRYADIVTHRLVHAALNKKEVPYTRCEIEDICYHINEVSRRAKQYSKQCRALHYGHVLRRNP---AMFNGFIETVSDKCIQLCIPGMQGLPQNCRELQLNLLGVSRKPDIIKDRDDDRPFDILTLAWQKRLYSHRGYAPSTRGLEN-IRVDPHQRAIFQQYLRWQDLLKVLVHGDTKLLKKNFAVNADYQEGDQLKSYV-PACTS---TVVDVSSEVRQGAITKHFCEFSMSFNHAQILLVQIGAEPQKGVLVPTPQILELTNNFILCLQHTSDPVKYLAKYAT----RKAHTENYKSIAEYLEVWLSLIRMEAATMAGHD-DAITVNDLPVKL----------NEKDGTFSMTMDFCEDRNIEFSSMSMEFILHGNEDDENSDETKYVPSS-------DFLCLKCRYEVDDVIYKGLKGSPGEQRIWLAHGQVDKIKKM----KKMGRIEVHFLLHPSSQSLPPQLLNSERKPKCSVEIMAKPESNRRTEAALLCLDKANGLAQKIAMRFKIPALDKNHLALARRMEAEVDVVGLARNNTKQYQAIQQALTNRFTLIQGPPGTGKTFTGMKLLYLFTKLNRVWHQEGNPLKQVVYCGPSNKSVDLVARWTKKKLGEHAPRMVRMYGSSHECMDFPIPGKLYSHKSRRAKNRPDEDLQDIALHRLIRQEGKPHADEILEFDKYFQQFHNC-PSISDHDLAETFKNKLKDYNSLLSKAGQEEL--QHYDVIFCTTAMTTNPKFIRGTKDKIFQCIIDENGMCTEPESLATIIAT--KAEQVVLIGDHKQLRPVVMCQHAARLGLEKSLFERYS----EKAVFLSTQYR---------------------MNPRICDFVS-------------------------------AEFYNDKLDTA-----PSRAW--KEETPLSIW--KYPDVPH--IFCHVEGEEEYLTVSTEEGNEHSCSNKAEVEKVMQVFRRMLKT---EGVNPRYINIISQYNAQCHAI----KTALVDSGYINCNVNTVVASQGGEWDYVIFSTTRSLPDYKIEPIPTLGWCKQNLGFITDEHQIDVALSRARKGLVIIGNENLLQCHKVWKHLLDHYRKRECVV 2218
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BLAST of Helicase with zinc finger domain 2 vs. TrEMBL
Match: A0A2R2MRF9 (helicase with zinc finger domain 2 OS=Lingula unguis OX=7574 GN=LOC106154479 PE=4 SV=1)

HSP 1 Score: 474.552 bits (1220), Expect = 7.670e-133
Identity = 489/1808 (27.05%), Postives = 792/1808 (43.81%), Query Frame = 2 
Query:  875 KQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIIN--------EKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLP----------SGAIVFTIDNKTTKDMDDAISYHREMN-QIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNR--EEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKA-----KCLLQ--YDEYFNEFYVHITDWYH-----ISNPS-YYNCSEK--DSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHK-IDIDDCSL-DIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEI-ICAHPLLQVASSDNRIKFANLSLDEVPVLSK-SNENFGKCNLKWR-----KIIFSCPPYLNSSSS--------NDNKF------KIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFC---NLRSDIFHKEIYKIFNRYEYLIASG-------------------ISSVG--GDL---------------LCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVN----FTLDIYQKSIVSIRQQVIMNKIDKIELL-KEVILG-AETNKKINNPTEKII---------------------------AQIENELNWK--------------KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKEN--KNSVVLYCGPSNDCINLVASTMMEKFNEK-----------CPKLLRIFGKEQEVSDFPIPGH----FFKNKTLPIDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCT-TSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLL-ETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCV 5803
            K+L E   K  LC L I  +Q   AIPI    N++   I L  R   G   F   IV V++ N           + GKV+GV+          + C +   + NL  P+ ++ PKI                        E   F D  + ++  AD   +S+     +     M I    +         + + +V Y KW P  ++P G  VG L    SL+  + L+  +   +L++  P +      + ++   L K H  +P           G +  TID   T+D+DDA+S     + +  IGVHI+DVT +V     + K+A+    + YPP   + P   +  ++L T   SLV G+ R  +SV F F +N         + + +P  +  V+ SK KL+YEE  + L  +     ++ ++  AL+ ++ IA K R  RL          + +   Q      A + +EEFM+LAN  + R + E +    LLR+Q P  +   + W +  ++    + A  LK+Y      L +  N+       ++  +L   +++++ + KA     K   Q   D +  E +V +    H     +  P+    CS     S + GH  LN + YT FTSPIRR+ D+VVHR + +++ K +D    S  ++++IC   N   +  K F   CE      +  +     +  V + ++D  I +C      + S   R++F ++ L++ P L K +   F  C L+W+     ++    PP               N N+F       +   + ++    +   L   I+  + +   +  + N+L   F +   ++       +        +L + +   +R+        G +     L  ++P+ HICL H ++P   F     +  L     E+++  K Y+    PL++ E    A+ D  + T+  V + W+       K    YG + L   FC    +R     ++        + ++ +G                   +S  G  GD                +CL     D  + W+GHG +V + +      + K ++F+L      +P++ E+ +     T++   + + SIR +  +  + +  +L + + LG A+    IN+   K +                            + E+ L+ +              + N+ Q  AV +A+ +  SLI GPPGTGKT+ G  L++ +   NR+ +  +   VLYCGPSN  +++VA    +KF  +           CPK+LR++GK     DFPIP        K+       ++++LH LIR  G   + ++ + D  FK    KDP+  D ++   I  YK LV +A+++ I   + D+ILCT T+   K V+    I Q I+DE+GMC EP+ L+PI  +    K +VLIGDHKQLRP++ ++LA   GL+ SLFERY    P+   MLN QYRMHP ICDFPS EFY G+L    SP      SD M                               +++F   +      +  WP  R+ P     KRF       +   V GEE S  ++T  G E SK NK E++ V  IY  L+ +T     L+   I VL+QY  Q + +E   K    ++      V TV+ SQG E D VIFSTVRS+    I   PT GW + +LGFIT+ +QINVALTR ++ LIIIGNK+LLK + T+KKLI + EE   V
Sbjct:  469 KKLREDPSKYKLCTLYIETNQKAHAIPIGT--NEQIPRIELYGRIRSGL-AFNESIVVVEVFNPPENDPIPSHTYRGKVIGVWLEPRVKKFSRFACTIDDYRSNLAKPICRTAPKI------------------------ELLGFPDNVREKDE-ADVPIYSVEYDGQLKYKKKMKIEAKYKD--------DIILLVRYLKWKPFRVFPLGVAVGVLKGSASLEREMRLL--MIQHDLVKTFPTH------VADRVKALSKKHKKIPVHEFKKRLDYRGVVTLTIDPADTRDIDDALSVEDIGDYRTRIGVHIADVTHFVKKDDFIDKEARARGVSFYPPS--DQPRIFMLPDELTTSMCSLVEGEDRLALSVFFDFDQNG--------NMLSEPTIKRTVVKSKQKLSYEEAEMILCGT----GLENEISNALKQLHHIASKCRAQRLKEG-------SAFNQFQDNGAPMAHVTVEEFMILANVTIGRSLGESF-QHVLLRVQDPPMDLALQMWQKEFNQVAKHSAA--LKKY-----RLKYGANAPSGLKQVQQQGQLGTLYVREAVWKKALEVSRKGAGQELLDIFSREHHVPLIYSAHWKINELQRPARMAACSSTAIPSQDKGHHGLNMTDYTWFTSPIRRYVDIVVHRFVHAMLDKSVDTPPYSQKELEDICKEMNALHRKAKKFHGACELIQFCLQLKENKTSTILPVVTALDDSFIQLCLPCCKDIPSRHLRLRFGSMGLNQRPSLDKGTGAVFQFCPLRWKKRLYDRVAVPKPPGGKRQKQRAQDWHDVNPNQFLTPMPVGVWDGIIEAVSQQNAQALSTLIKMKHKTIANMAQRENEL---FSANINTDAYRKSDGTIANKESKFQLKVTLGTVVRVLAQAKFHRGSLCPRLSLMSLSPNVHICLKHHDDPVACFCDISPVKPL----DETYTDEKTYQSTLIPLLQIEGAQAAVIDEVSLTVSNVRVSWM------KKNANWYGSVVLGDTFCEDRGIRLSSSQEDDGDAAANPDRIVDTGEYRGYVCIVYRNLPPDSQCVSDSGATGDCPIDHQSTHSEPSSRSICLPQYNSDAESTWLGHGLIVHVRR------RDKRVVFKLLDGI--IPETIESKSNPKLATVEFLDRIMPSIRMENAVRSLGEATILARNIALGKADLRDVINDRDWKDVEAFFYLHEEDPKKRMERERKKRREPSRVKPEDLLDRRTRYSKGRYLENYLPRANKRQREAVISAIMKPFSLIQGPPGTGKTLTGIRLAYLFVEWNRRNSPEERKHVLYCGPSNKSVDVVADFFKKKFTPQQYDPNDERPSICPKILRVYGKSLVNRDFPIPKEPDLLRGKDAVSTERHKDIALHHLIRSKGTKISKDILELDAKFKSY-FKDPVKNDVSL-EIINHYKRLVAQAEEDEI--KQHDVILCTCTTAGSKAVLRSGIIEQSIVDESGMCVEPDCLVPIVHS--KAKQIVLIGDHKQLRPIVLNQLARDMGLERSLFERYATQFPKQTIMLNKQYRMHPDICDFPSSEFYDGQL---YSPPVLRFASDPM-------------------------------FRDFTPAA------EVLWPRIRQGPMLIEDKRF-------VMCHVEGEEESLVISTPEGGEMSKKNKAEIQEVERIYSILVSKTSL--NLSKANIMVLSQYRAQVNGIEKALK----ERHGEGVQVSTVVASQGGEWDIVIFSTVRSIPEYQIVQRPTKGWCKVNLGFITDDHQINVALTRPRRFLIIIGNKQLLKCDPTFKKLIAHYEENGRV 2123
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BLAST of Helicase with zinc finger domain 2 vs. TrEMBL
Match: C3XYY1 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_90929 PE=4 SV=1)

HSP 1 Score: 466.463 bits (1199), Expect = 2.001e-129
Identity = 442/1736 (25.46%), Postives = 760/1736 (43.78%), Query Frame = 2 
Query:  857 YDVYTPKQLDEM----KDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKII------NEKFHS------GKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILD--------KPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQI-VIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIV-EETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPP---YLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEA---------LENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNP-SKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHK----------EIYKIFN----RYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKS----AENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNS-------VVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFF--------KNKTLPIDIQEVSLHFLIRK-NGGYADELKKFDNIFKCIRNKDPIPPDFNVY-NAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAA---------KSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKS---ILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            Y  Y+P++L+ +     D+   C+L +  + +        +      +I++ SR+N G   + ND V V+I+      +E F +      GKV+G+ +S      + +VC V  +  N+MVP++   PK+   N  G+   +N+  N  +  S               Y  +  F       I+                  D  + LFVV + KW P F+YP G +   ++   +L  S+ ++      N   +  KY+ +V+    +   +D             L     VFT+D   + D+DDA S  R ++    +G+HI+DV+ +V   S++ K+AK+   T Y   +   PP H+  ++L+    SL+P + R  +SV   F        N +   +V+P+    VI S+ KL+Y +    ++       V  ++   +  ++ IA   R  RL  ++          + + E    A  ++EE M+LAN  VA ++ + +P  T LR Q P K  +E LE+  +      +G   E    L           +  + ++ ++         D ++ + L+  DE        +     I + + + CS  +     H+SLN+S YT+F+SPIRR+ DVVVHRLL ++I K      S ++ EIC + N      K +E+      +  +  NK    ++  V   ++ +EI    P   V  +++R +    +L +   +    +  G   ++W++ I+   P    L   S      ++DS  +   +P    + +Q +     +G           +E+ +    T            +    F +     ++       +++Q       GL+    +LF +TP   +CL H+ +  ++F +   +   + N  +  + S++ Y++ + P++  E+   A+ +  +  +    I W   +   T +    G ITLS  FC  R   F +          +  K F+    RY  + A+       ++   +  ++     WVGH  V+   +          +  +L Q     P +      ++  T++I  K++   R +  +  +     L + I   +      NP    I  IE    +   N+ Q  AVK A++Q  +LI GPPGTGKT+ G ++++    +N++    S        VLYCGPSN  +++V   M  K  +   K++R++ +  E  +FPIP            K   +  +  +VSLH LIRK +  +A+ +K F+++FK         P++ V  N I TYKN + KAK   + +    +  CT + + K  +   NI Q I+DE GMC EPE+ +PI  A           + K V+LIGDH+QLRP++  + + + GL  SLF+RY        TML +QYRMH +IC FPS  FY  KL TH                                             +  ++   + A+ D  WPG   RP                F  V+G+E  Q+V T  GN+ S+ N++E ++   +   L+       + P  + +L+QY  Q  L+  +  S    L  +      V +V+ SQGSE DYVIFSTVRS+   +I  NP+  W +K+LGFI + NQ+NVA+TRAK+GL +IGNK LL+V+  W KLI + EE+ C++
Sbjct: 2206 YTNYSPEELENLLRDHPDRYRRCRLVVKGTYTAYG----EVIGADEDDILINSRKNRGLG-WANDEVVVEILKNTDQESEVFKTSSDIRRGKVVGIIRSAVSLHLRKFVCVVDNNNPNVMVPINTDAPKLVAYNYLGK---ENRRPNSVRVYS---------------YMTDGSFKFKTYEDIDPR----------------DPYKKLFVVRFLKWTPRFVYPLGLVTDVITPDSTLDTSMEILN-----NRFNVPSKYKGKVEEDVNRRYFVDWQIPQKERNQRKDLSRTHTVFTVDPPESMDLDDAFSIERNLDGTYTVGIHIADVSYFVPVGSDLDKEAKERSTTLY--NHTGKPPVHMIPKRLSEGVCSLLPNRDRLALSVFVNF--------NSEGDIVVEPQMERCVIHSRAKLSYAQAEDIIEGWGS-LTVPQEVQDGVRVLHTIAAARRQKRLGPAHLYHQ-----PDEEREGAVRAHAMVEEMMILANTKVAEVLRQNFPEVTPLRKQQPPK--KEKLESWRQRHG-GLSGYSVELAKSLPNGESTDTPTAEIPLLKEIWDEIRLAALSGDLNRIQQLVCTDENHPTLARALLQLRGIQDRAQFTCSAAEPSE--HYSLNQSAYTYFSSPIRRYIDVVVHRLLVALIAKQPPPYTSDEMKEICSHYNNMENNAKTYERETLVLKLAYDWMNKP--EVMYPVIDTVDGQEIQLLMP--SVRHTESRQRRVAFNLLKPAAMPSPEDEGGSVEVRWKQRIYDTAPDKTKLPWPSDRKKPLQLDSEKYVIRIP---GQYWQRLVEHVQTGNIDLIKCVVTYIEDVVGMQLTLGPKVFEEVSSEAKEGMFADHFCTFQMTYTPGQVVKVQLTGDIQKGLLSPCIQLFNLTPKMDVCLDHRRDAVTRFAVPATQS--VRNMTR--YRSVQMYQNRWLPIMAVEAAHCAMENNESVFVHGTFISWEKQQHQTTGEVAYIGKITLSQKFCKDRCIHFDQGNQNKLTSVNDTGKHFDYICVRYTGVRAAMTHDGRFNIAADKTEEKHPLVCWVGHCLVMPGVEYTTRQDGDITVPIKLHQHLMAFPDTLLHHGTSIPATIEIITKTLPDRRMENAVRWLSGSSHLVQQIATGKNITARGNPLANEIT-IEPLPAFFPLNQVQELAVKQAISQPFTLIQGPPGTGKTVTGVHIAYFLAEMNKRIQSVSGEGMYPPQVLYCGPSNKAVDVVTGYM--KKIKGGLKIVRMYSEMIEREEFPIPNEPVHPNKCKSEKESKITNEHDDVSLHHLIRKPSNPHAETIKAFESLFK--------DPNYTVTENDITTYKNHIIKAKIHELRQKHVILCTCTAAASPKMGMAT-NIEQCIVDECGMCTEPESFVPIVGAPVERNGSMTFHNPKQVILIGDHQQLRPIVLEKTSQQLGLDTSLFQRYAWK----ATMLTIQYRMHEAICSFPSRMFYENKLRTH---------------------------------------------RTVIERPRHPAL-DRLWPGGDNRP--------------TAFCHVVGKEEVQTVATAEGNQMSRSNEMEADMAVKMAICLVREHG---IKPENVILLSQYRAQCALINKKLSSERKRLNDERVERVGVNSVVSSQGSEWDYVIFSTVRSLPSYEIEQNPSPSWLRKYLGFIMDQNQVNVAITRAKRGLCVIGNKNLLRVHTLWNKLIIHYEEQKCLV 3786
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BLAST of Helicase with zinc finger domain 2 vs. TrEMBL
Match: A0A1S3IYB3 (helicase with zinc finger domain 2 OS=Lingula unguis OX=7574 GN=LOC106168606 PE=4 SV=1)

HSP 1 Score: 454.907 bits (1169), Expect = 2.969e-127
Identity = 481/1792 (26.84%), Postives = 776/1792 (43.30%), Query Frame = 2 
Query:  899 KLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIIN--------EKFHSGKVMGVYQSFHKPVNKL--YVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLT---NMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKY-EKEVKTIREKHMILDKPHITLP---SGAIVFTIDNKTTKDMDDAISYHREMNQIV-IGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNR-EEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFE-LFNEFIKQSDFDKAKCLL------QYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDD--CSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQ-VASSDNRIKFANLSLDEVPVLSK-SNENFGKCNLKWRK-----IIFSCPPYLNSSSSNDNKFKIDSHLFDSYLP---YSD----------SKLFQEIRRSY--LSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSD------------------------------IFHKEIYKIFNRYEYLIASGISSVGGDL---------LCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNF----TLDIYQKSIVSIRQQVIMNKIDKIELL-KEVILGAETNKKINN---------------------------------PTEKIIAQ---------IENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSV--VLYCGPSNDCINLVASTMMEKFNEK-----------CPKLLRIFGKEQEVSDFPIPGH----FFKNKTLPIDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILT-YKNLVKKAKKEYIVKNKFDMILCT-TSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLK--SDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCF---HKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLL-ETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLE 5788
            K  LC L I  +Q   AIPI    N++   I L  R   G     +D+V V++ N           + GKV+GV+  F   V K   + C +     NL  P+ ++ PKI +                          F D  + +    D +Y  ++ +    QL     M I    +         + + +V Y KW P  ++P G  VG L    SL+  + L+  +   +L++  P +    VK + +KH  +    I       G +  TID+  T+D+DDA+S     + I  IGVHI+DVT +V     + K+A+    + YPP   + P   +  ++L T   SLV G+ R  +SV F F +        K + + +   +  V+ SK KL+YEE    L  +  P  +       L+ ++ IA KI+  RL          + +   Q +    A + +EEFM+LAN  + R + E + +  LL    PV +  + W +  ++      +  LK Y       N    S+Q+ + +    E L+ + ++ S     + LL      Q+       + ++ +    +  + Y+ +   S    H  LN + YT FTSPIRR+ D+VVHR + +++ K D        ++ EIC   N   K  K F   CE      +  +     +  + + ++D  I    P  + + S   R++F ++ L++ P L + +      C L+W+K     + F  P          +   ++ + F + LP   + D            L   I++ +  ++ EA E K      KF     ++   +   +       ++L M +   +R+        G +     L  ++P+ HICL H ++P   F     +  L +    +++ +K Y+    PL++ E    A+ D  + T+  V + W+       K    YG + L   FC  R                                I ++++        Y  A+G   V             +CL     D  + W+GHG +V + +      + K ++F+L   +  +P++ E+  +    T++   + + S+R +  +  + +  +L K + LG    + + N                                  +E +  +         +EN L   + N  Q  AV +A+ +  SLI GPPGTGKT+ G  L++ +   NR+ +      VLYCGPSN  +++VA     KF+ +           CPK+LR++GK     DFPIP        K+       ++++LH LIR  G   + ++ + D  FK    ++P+  D ++  AI+  YK LV KA+++ I   + D+ILCT T+     V+    I Q I+DE+GMC EP+ L+PI  +    K +VLIGDHKQLRP++ ++LA   GL+ SLFERY    PE   MLN QYRMHP ICDFPS EFY G+L +       GL+  SD M                               +++F   +      +  WP  R+   Q      KRF       +   V GEE S  ++T  G E SK NK E++ V  IY  L+ +T     L+   I VL+QY  Q + +E   K    ++      V TV+ SQG E D VIFSTVRS+    I   PT GW + +LGFIT+ +QINVALTR ++ LIIIGNK LL+ N T  KLI + E
Sbjct:  169 KYKLCTLYIETNQKAHAIPIGT--NEQIPRIELYGRTRSGLAFNESDVV-VEVFNPPKRDPIPSHTYRGKVIGVW--FEPRVKKFSRFACTIDDYSSNLAKPICQTVPKIKLLG------------------------FPDYVQEK----DESYVPIYSVEYNGQLKYKKKMKIEAKYKD--------DIILLVRYLKWKPFHVFPLGVAVGVLKGSASLEREMRLL--MIQHDLVKTFPTHVADRVKALSKKHKKIPAREIKKRLDYRGVVTLTIDSADTRDIDDALSVEEIGDDITRIGVHIADVTYFVKKDDLIDKEARARGVSFYPPH--DQPRIFMLPDELTTSMCSLVEGEDRLALSVFFDFDK--------KLNKVSKHTIKRTVVKSKQKLSYEEAEDILCGTGLPNEISN----TLKKLHHIASKIQAQRLKEG-------SAFNQFQDKGAPMAHVTVEEFMILANVTIGRSLGESFQHVLLLVQDPPVDSALQMWQKEFNQVAK--HSTTLKNYRRKYDT-NAPPGSKQRQLATLHLREALWKKALELSRNGGGQELLEIFSREQHAPLIYSAHWNLIELQRPTRMAAYSSAAIPSQYKRHHGLNMTDYTWFTSPIRRYVDIVVHRFVHAMLDKADDTPPYTQEELKEICKEMNALHKKAKKFHGACELMQFCLQLKENTTSTILPIVTALDDSFIQLRLPCCEDIPSRHLRLRFGSMGLNQRPSLEQDTGAQIQFCPLRWKKKLYDRVAFPKPTDGKRQQRAQDWHDVNPNQFLTPLPVRVWDDIIEAVSQQNPQALLTLIQKKHENIASEAQEEK-----EKFNVNINTDAYRNRDGTIANKESKLQLKMTLGTVVRVLAQVKFHRGSLCPRLSLMSLSPNAHICLKHHDDPVACFCDISPVKPLDD----TYTDVKTYQSTLIPLLQIEGAQAAVIDEVSLTVRNVRVSWM------KKHRNWYGSVVLGDTFCEDRGIRLSSSQEDDGDAAANPDRIVDTGEYRGYVCIVYRDLPPDSQCVSYSGATGDCPVDHQSSHSEPSSRSICLPQYNSDAESTWLGHGLIVHVRR------RDKRVVFKL--HDGIVPETIESKTYPKLATVEFLDRIMPSVRMENAVRSLGEATILAKNIALGKANLRDVMNDRDFKDVKTFFDLHEEDPEKKKQRKKRKEPSRVKSEDLFDRRTIYSKGRYLENYL--PRANEKQREAVISAIMKPFSLIQGPPGTGKTLTGIRLAYLFVEWNRRNSPGERKHVLYCGPSNKSVDVVADFFKRKFSPQQYDPNDERPSICPKILRVYGKSLVNRDFPIPKEPDMPRAKDAVSTERHKDIALHHLIRSKGTKISKDILELDAKFKSY-FENPVKNDVSL--AIINRYKRLVAKAEEDEI--KQHDVILCTCTTAGSNAVLRSGIIEQNIVDESGMCVEPDCLVPIVHS--KAKQIVLIGDHKQLRPIVLNQLARDMGLERSLFERYATQFPEQTIMLNKQYRMHPDICDFPSSEFYGGQLYSQ-----PGLRFSSDPM-------------------------------FRDFTPAA------EVLWPRIRQDRRQRRRVEDKRF-------VMCHVEGEEESLVISTAEGGEMSKKNKAEIQEVERIYSILVSKTSL--NLSKANIMVLSQYRAQVNGIEKALK----ERHGEGVQVSTVVASQGGEWDIVIFSTVRSIPEYQIVQRPTKGWCKVNLGFITDDHQINVALTRPRRFLIIIGNKNLLRCNPTLGKLISHYE 1806
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BLAST of Helicase with zinc finger domain 2 vs. TrEMBL
Match: A0A2R2MN27 (helicase with zinc finger domain 2-like OS=Lingula unguis OX=7574 GN=LOC106167792 PE=4 SV=1)

HSP 1 Score: 430.639 bits (1106), Expect = 7.023e-119
Identity = 388/1385 (28.01%), Postives = 623/1385 (44.98%), Query Frame = 2 
Query: 1877 KLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREE----WLENL-HESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVN-MGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQ-VASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENK-LNQLCTKFXXXXXXXXXXXXXXXXXEPIVD----IELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEI------------------------YKIFNRYEYLIASGISSVG---GDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRL-TQSNFDLPKSAENVNF-TLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGA------ETNKKINNPTEKI-IAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNS------VVLYCGPSNDCINLVASTMMEKFNEK-----CPKLLRIFGKEQEVSDFPIPGHFFKNKT-------------LPIDIQEV--SLHFLIRK-NGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            +L+ D  SL  G+ +  +SV+F  +++ +  K        +P   E VI     LNY EV   ++            +  ++ +Y ++  +R  RL    F     +   +LQ  + F++  L+EE+M+ AN++VA ++ + YP+ST+L    P   REE    W +N  H   N+ +    +     LG  N  +    K  +    ++     +   D+  A  L+  ++   +    +  W+ I       CS     N + H  +N   YT FTSP+RR+ D++VHRLLK+ +  +     S  + +IC   N      K+F K C+  A   + +         +   + ++ I+  +P    V      IK+A+LSL E P L + N+   +  L W K I+   P   S + + ++ ++D+      +   D   +Q +   ++ G+   +K   Q   K V     +   +        I D      L +   + +++ F      G ++   ++  +T  FH+C+ H+ NP   F      D+     KE +  I EY+  + P++  ES  EA+    +F +  V I WI  +  K       G  +L  +FC  R   F K++                         + F+ Y  +I   I +     G+   +  R +  +  W GHG +  +       ++   I F+L  +S     K  +  +  TL++  K+    R +  +  +DK   L + I         +T + I  P E I  +Q + E    K N +Q NAV  ALN   SLI GPPGTGKT     + +     N++   N+       +L CGPSN  ++ +AS MM  FN+K     CP  +R++       DFP+P      ++               ID+  +  SLH+LIR+ +  Y+ ++ +FD +FK         P    +  +  YK  V KA++E +   + ++ILCT SV+  Q +T  N  Q++IDEA MC EPET++PI A+  +   V+L+GDH+QLRP++  + A   GL +SLFERY         ML  QYRMH +IC FPS +FY GKL T                    S    K  E+ I W+G D                                           P+ I+F    G+E +  V T  G+E+SK N+ E++ V  +YK L+       + P+ I VL+QY  Q + ++ E     L+K    P V TV+ +QG E DYV+ STVRS+   DI   PT GW +K+LGFI + NQ+NVALTRAKKGLII+GN  LLKV++ WK L+E  +E+ CV+
Sbjct:    5 RLSEDLCSLRSGEDKLTISVIFTINKDGLFTK--------EPSIVESVIFCDKNLNYNEVEQIIED-----QTTTKEFFPVKMLYDLSHALRIKRLGTGAFFLYDAD---HLQDSSNFKSHQLVEEWMIEANKHVAGVLLKAYPDSTILVQHLP--PREELYTIWKDNFKHFLPNMLYFDPHRLQLPCLG--NVPQYVMPKVEIKEDIWKAIENAVNCDDWKTAFTLVCQEQKHPQHAHVLQQWFSIQMHRRVTCSAYVKPNEIVHSGMNIGPYTQFTSPVRRYIDLIVHRLLKAHLGNMASPYNSEAVQKICHLYNLGVLKQKHFSKDCDCLAYAFKLSSDPVRPHYTIVEAMEEDHILFRNPDYNFVPKRCETIKYASLSLQEKPELPEDNK--ARTVLAWGKRIYDQIPN-ESQALSVSQTELDTKRHVRQIAGRD---WQIMLDKFMKGDQDGSKNFLQKIVKNVKRRQVDPYLTSESPGGGMIFDHFKQFSLLLKGGDVLKLFFTAEIERGFLRPRVQILSLTDQFHLCVHHKENPIICF-----EDMASKASKERYRDIDEYQQIWRPILSMESAYEAVKSDESFYINNVKITWI--QDEKNNLPVYKGQFSLGKEFCKQRHIFFMKDVNGDEVEDSDADEDEDESDSEETNDLEHFSEYLCIICPRIPAAAQTYGEREQMGERDKGESYIWTGHGVITGVK------EQGSYIHFKLHDKSCHPTEKMLQQPSVCTLEVIPKTSTDKRMEHAIENLDKASTLAKGIATGNLSDIDKTREGIKVPKEFIEDSQKKLERYIAKMNFSQKNAVTEALNSPFSLIQGPPGTGKTWTALNMLYILNEWNKQGLNNADPDTSPKILVCGPSNKSLDHLASMMMYHFNQKDKENICPNFVRVYSDTIVSQDFPVPTQPVHRRSWKKMSTNGDEEDDTEIDVHCIPQSLHYLIRECSNRYSKKILQFDEMFK-------TEPLLVTHEDVTKYKATVAKAEQEAL--QQAEVILCTCSVSGSQKLTGLNFRQLMIDEAAMCMEPETMVPIVAS--NAYQVILLGDHRQLRPVVPLKAASDLGLALSLFERYSYK----AMMLKTQYRMHETICQFPSEKFYGGKLET-------------------DSSLKGKSPELEI-WSGRDE------------------------------------------PQAIVFCCTEGKETTLPVATREGSERSKSNEDEMKHVVRMYKNLVTK---HNIEPSNIVVLSQYKAQVYAIKKE-----LEKIIPYPNVSTVVGAQGGEWDYVLLSTVRSLPDYDILERPTLGWRKKNLGFIIDSNQVNVALTRAKKGLIIVGNDNLLKVDKVWKSLLEYYQEKGCVV 1265
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Cavefish
Match: helz2 (helicase with zinc finger domain 2-like [Source:NCBI gene;Acc:103025927])

HSP 1 Score: 295.049 bits (754), Expect = 1.043e-79
Identity = 365/1480 (24.66%), Postives = 641/1480 (43.31%), Query Frame = 2 
Query:  911 CKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKII-NEKFH-SGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNK-----IKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGA------IVFTIDNKTTKDMDDAISYHREMNQIV-IGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDAD-LYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTE---NRFEAELLIEEFMLLANEYVA-RIIYEKYPNS-TLLRMQSPVKNREEWLENLHEST------NLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIK-------QSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSY-YNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICV-----NANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDN-RIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFS-CPPYLNSS-----SSNDNKFKID------SHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCR--KEDWNNY------------------WVGHGHV--VTINKCMINNQKMKLIIFRLTQSNF-DLPKSA--ENVNFTLDIYQKSIVSIRQQ-VIMNKIDKIELLKEVILGAETN------KKINNPTEKIIAQIENE--LNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRK----------ENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPG-------HFFKNKTLPIDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCT-TSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHV 5035
            C++ + +  SG A+P++  A +    I +  R N G   F  D+V V+I+ +E F   G+V+ V +  H  + K +VC +  +   +M P++   PK+          +K+K     I+N  K  + E+   ++++  RN                                       +LFVV + +W   F YP G ++  L    SL++          L +L+   + E+ V    +K M   K    L +G       + FTID   ++D+DDAIS  R++ +   IG+HI+DV  +V   S++ K A+      Y  +     P ++F +KL+T+  SL+PG  R  +S++ +  +        K   I +  F + VI SK +L+YEE    L+ S    N D D L   L   ++ A   R  R    +       CY +   +    R +++ L+EE M++ N  VA R++ EK   S T LR Q   +   + L   +E        +++ + QL  Y         N ++ Q+      FF +    ++       + D  K   L+  D+        + +   +   S+    +   +  +GH+ L    YT  +SPIRR+ DV+V RLL SV+    +     ++D+ CV     N+N +S   +    L     +  +  ++   I++ V    N+ +I  + PL + +  D   I + +L L++ P   ++ +      L+WR+ ++S   P +++      +++  KF  D        L  +        +F+E+ +  L+    +  +                        E  +++ L++     + +Q       GL+  + +L VV P F ICL H  NP   F    K  L  ++   S     +    ++PL E ES   A+++  +  +E   ++W         K + +G   +  D                  + ++ I S + +     LC+R R  ++D N                    W+ H  V  VT  +  + +   K I FR+      ++P+    E   FT+++  K +  +R+   I N      L+K + +G +T       +K N P      +IEN   L + + N +Q  A++ A+N + +LI GPPGTGKT+VG ++ + +   N+K          + K   +LYCGPSN  +++VA  +++   +   K LR++  + E+ +FP PG       H  + +     ++ ++LH  IR     Y  ++ +FD   K           +     I  YK+ +KKA+K  ++++  ++ILCT T+ +   +    N  Q+IIDE  M  EPE  IP+       K +VL+GDHKQL+P++ + L  + G++ISLFERY         ML+ QYRM   IC FPS EFY GKL T +
Sbjct: 1305 CEIVLERYDSGYAMPLDEPALR----IDIKGRHNLG-QSFSGDVVSVEILTSETFPPKGRVIEVLK--HSALTKEFVCTIDTNDNQVMTPINICIPKLFTP------FWKDKPNHIAIRNPEKR-NAEKFIRINEKARRN---------------------------------------HLFVVKFLRWGKRFNYPLGMVINVLPKVTSLEE---------GLKVLDKEYQLERTVPLPVQKEMESFKTTPLLTNGRKDFRDLLTFTIDAPKSQDLDDAISV-RDLGECYEIGIHIADVASFVDKDSKLDKYARQQGTAFYVSER---EPTYMFPDKLSTNDFSLLPGSDRRCISLMTEVDK--------KTHRIQKRTFYKSVIRSKKRLSYEEAEEILRSS---GNNDFDTLEGCLVKAFQFAEVHRKCRKQSDW-------CYKSPDEDVVIGRRQSQKLVEELMIMFNHTVADRLLSEKKTTSLTPLRCQD--RPNPDELHKFYERNVPMLPMSIHLSSQLNHY-------EKNDDTEQE-----TFFPILTSVLRNLQIAAQEKDVYKLLDLITTDDLHPLLLPLVINLRRLIYKSHVLRANSTHTSRIGHYDLELDCYTWASSPIRRYVDVIVQRLLHSVLEDDRVQYTPQEVDQCCVDFTLRNSN-QSSCQRASHHLSFASKLSAQNEEKLAYIVE-VSPSGNNFQI--SFPLNRTSLPDTVGIMYRDLQLEDQPRYIEATDCMV---LRWRRRVYSLTSPSIHTELKQHEANSRGKFITDVPMESWKRLVSAIRKEEWDVMFEEVEQLSLTDVRRKTTVQ--------PALIGARMDMLNQREEHYIELSLELKKGKMIEVQLGTDTYRGLLVPSVQLLVVNPKFEICLEHTKNPIMCF---SKYALFSSSESYSSYMEYQR--IWKPLCEMESACSAVAENESIVIEDASLEW------DRSKDDLWGSFRMPVD-----------------KKAQWAIESNLRNC---FLCIRMRMQQKDQNPILEDSDSKDMDLVDVPGLIWIAHAVVTKVTGEEKSVKSTYTK-ITFRVNHMPMTNIPEKVFMEGTRFTVELIPKLLPDVRKDNAIENLTSANNLVKNIAMGKKTQDERNTIQKCNQPR----FEIENHRSLGYPQLNNSQCKAIREAMNNEFTLIQGPPGTGKTVVGVHIVYWFFKQNQKLPPCQKLGDEDLKKRCILYCGPSNKSVDVVAGQLLKLKEKL--KPLRVYSDQVEIMEFPYPGSNLKISRHCQRVEKPNEALRSITLHHKIRMTSNPYHKQILEFDERIKA--------DQYLTDEEIKCYKDCLKKARKHELLQH--NVILCTCTAASHPVLADALNFQQIIIDECAMATEPEAFIPLVTHKP--KQIVLLGDHKQLQPVVHTDLLQRLGMRISLFERYTN----KALMLDTQYRMQKDICAFPSEEFYRGKLKTGI 2617

HSP 2 Score: 127.102 bits (318), Expect = 1.777e-28
Identity = 71/183 (38.80%), Postives = 109/183 (59.56%), Query Frame = 2 
Query: 5273 PERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            P  I+F  V G+E+S  V+T  GNE SKGN  E + V  I + L+++     + P  I +LT Y+ Q +    E  ++L      +  V T+++SQGSE  YVI STVRS  + +I   PT  W +K LGF+ + +Q+NV +TRA++GL +IGNK LL+    W+KL+ + E++ C++    N
Sbjct: 2631 PTSILFGHVEGKELSLVVSTERGNENSKGNIEEAKAVVRIARNLIKSG----IKPKEIAILTPYNAQVN----EISTVLNTNGIRNVTVNTIMKSQGSEWKYVILSTVRSFPMSEIEIQPTKAWLKKRLGFVMDPHQVNVGITRAQEGLCLIGNKNLLRCCYLWRKLLTHYEDKGCLVDPAWN 2805
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Cavefish
Match: upf1 (UPF1 RNA helicase and ATPase [Source:NCBI gene;Acc:103031971])

HSP 1 Score: 165.622 bits (418), Expect = 1.336e-40
Identity = 177/680 (26.03%), Postives = 281/680 (41.32%), Query Frame = 2 
Query: 3803 GDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIE-----NELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q   + +    + +  + G   +K + +  E +I + +             N +Q  AVK  L + LSLI GPPGTGKT+    + +     +     N  VL C PS    N+    + EK ++   K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD    + +  +    Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  +LL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRA+ G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  339 GDEICLR-YKGDMAPLWKGIGHVIKVPDNYGDEIAIEL------RSSAGAPVEVPH-NFQVDFVWKSTSFDRMQ---SALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVY-----HLARQGNGPVLVCAPS----NIAVDQLTEKIHQTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSMPELQKLQQL------KDET-GELSSSDE-KRYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRIKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTRLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 884
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Cavefish
Match: ENSAMXT00000036328.1 (pep primary_assembly:Astyanax_mexicanus-2.0:5:1303467:1306311:1 gene:ENSAMXG00000040064.1 transcript:ENSAMXT00000036328.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 124.79 bits (312), Expect = 1.826e-31
Identity = 79/204 (38.73%), Postives = 117/204 (57.35%), Query Frame = 2 
Query: 5222 GKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQ----QHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            G ++ P +  + +    P  I+F  V GEE+S  V+T TGNE S  NK+E E    +   L+       + P  I +LT Y+ Q    + LLE + +    ++      V T+++SQGSE  YVI STVRS  + +I  +   G   K LGFIT+ NQ+NVA+TRA+ GL I+GN++LL+ +Q WKKL+ + E +NCV+    N
Sbjct:   20 GAQRGPCRLLNNK--NNPTAILFAHVQGEEVSLIVSTPTGNENSVSNKLEAEQAVRVADLLVRQSG---VKPEDIAILTPYNAQVCTIKQLLEKKSEK---REDMQGVTVCTIMKSQGSEWPYVIVSTVRSCPLSEIKSSKNKGRMGKKLGFITDPNQVNVAITRAQDGLCILGNRQLLESSQLWKKLVSHYERQNCVVNSAEN 215
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Cavefish
Match: mov10a (putative helicase mov-10-B.1 [Source:NCBI gene;Acc:103034927])

HSP 1 Score: 115.931 bits (289), Expect = 2.269e-25
Identity = 149/574 (25.96%), Postives = 230/574 (40.07%), Query Frame = 2 
Query: 4160 NRNQYNAVKNALNQKLS----LIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDM----ILCTTSVTLKQVVT----FFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKN-VVLIGDHKQLRPMIRSRLADKRGLQISLFER-------YQKLKPE-------LVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFP---PRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEE 5791
            N  Q  AV++ L+        LI+GPPGTGKT+    L  A   VNR     + VL C PSN   +L+           C +LLR                             V  H L R                 C  ++DP      +   +L + N   + +  +I+ +K  +    ++  T +T  ++V+      +   V IDEAG   EPE ++ IA      K  VVL GD +QL P++RS LA + GL +SL ER       YQK            VT L   YR HP+I + P+  FY  +L                +VF     + + + E + +W         +H            +P   +P                    +IF  V+G++  ++      N  S  N  E+EV+    +KL  T      P+L P  I ++  Y  Q   +    +++   K      V +V   QG E   ++ S VRS +I  +  +  F     ++GF+TN  + NVA+TRAK  LI++GN  +L  N TW++ I+  E+
Sbjct:  516 NPEQSTAVQHILSGHSKPGPYLIFGPPGTGKTVT---LVEAIKQVNRS-GTVAHVLACAPSNSACDLL-----------CERLLRY----------------------------VDGHHLYRL----------------CASSRDP----RTMPQKLLKHSNW-DEGQDSFILPSKETLMGYSVIVVTLITAGRLVSGGVPVGHFTHVFIDEAGQAVEPECVVGIAGLLHPEKGQVVLAGDPQQLGPILRSPLAQQHGLGLSLLERLMTQNSLYQKTHDGSQAYNSCFVTKLLRNYRSHPAILEIPNELFYDNEL----------------QVF-----ADQMEREAFCHW---------EH------------LPKQGFP--------------------VIFHGVMGKDEREA------NSPSFFNVSEIEVLISYLQKLKLTQGKKGLPKLKPADIGIIAPYRKQVEKIRKALQTVKELKQWNDIKVGSVEEFQGQEKRVIMVSAVRS-SISYVKMDQDF-----NIGFLTNEKRFNVAMTRAKALLIVVGNPVILNKNPTWQRFIQYCEQ 951
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Cavefish
Match: mov10b.1 (Moloney leukemia virus 10b, tandem duplicate 1 [Source:NCBI gene;Acc:556024])

HSP 1 Score: 107.842 bits (268), Expect = 5.607e-23
Identity = 149/574 (25.96%), Postives = 225/574 (39.20%), Query Frame = 2 
Query: 4160 NRNQYNAVKNALNQ----KLSLIWGPPGTGKTMVGCYLSFAYTFVNRKEN--KNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDM----ILCTTSVTLKQVVT----FFNIAQVIIDEAGMCKEPETLIPIAAAAKS-VKNVVLIGDHKQLRPMIRSRLADKRGLQISLFER-------YQK----LKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEV-EVVGYIYKKLLETCFP---PRLAPNFITVLTQYSYQ----QHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIE 5779
            N  QY AV N +         L++GPPGTGKT+           + + E     + +L C PSN   +           + C KLL                              V  H + R              I+   R+   IPP      ++L   NL   +  +Y   +K ++    IL TT+ T  ++VT      +   + +DEAG   E E +I IA   ++    +VL GD KQL P++RS +A + GL +SL ER       YQK      P  VT L   YR H SI   P+  FY G+L                      + + +    +Y NW         +H            +P   +P                    +IF  V G++  +S      +  S  N  E+ +V+ Y+ K LL T       +++P  I ++T Y  Q    +  + M  K + + K      V +V   QG E   +I STVRS   E IN +  F     ++GF+ N  + NVA+TRAK  LI++GN  +L  + TW + I+
Sbjct:  375 NHEQYTAVCNIVEGVSKPAPYLVFGPPGTGKTVT------MVEAIKQLEKCIPGARILACAPSNSAAD-----------QLCEKLL----------------------------PHVDSHKVYR--------------IYALSRSPAEIPP------SLLDCCNL---SGDDYEYPSKEELMDYKILVTTAYTAGRLVTGGLPAGHFTHIFVDEAGHAVESEAIIGIAGLLRAETGQLVLAGDPKQLGPILRSPIAIQYGLGLSLLERLMTKNPLYQKGETGFNPRYVTKLLQNYRSHRSILKIPNEMFYDGEL---------------------QARADEYSTSLYCNW---------EH------------LPKRGFP--------------------LIFHGVQGKDERES------SSPSFFNTTEITKVIDYLKKLLLTTQGKKGIAKISPKDIGIITPYRKQVEKLRKAIRMCDKELKVFKGIDELKVGSVEEFQGQERRVIIVSTVRSSG-EYINIDTDF-----NIGFLNNEKRFNVAMTRAKSLLIVVGNPIILSSDSTWSRFIQ 806
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008666.1 (pep scaffold:Pmarinus_7.0:GL478401:184246:194592:-1 gene:ENSPMAG00000007841.1 transcript:ENSPMAT00000008666.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 187.193 bits (474), Expect = 6.989e-51
Identity = 113/304 (37.17%), Postives = 174/304 (57.24%), Query Frame = 2 
Query: 4154 KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLS--FAYTFVNRKEN-----KNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGH----FFKNKTLP---IDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQ--VIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYS 5014
            + N  Q   +K +L    ++I GPPGTGKT+VG +L   F       +EN     K+   LYCGPSN  +++VA  ++ K  +  P  LR++G++ E  +FPIPG     F ++K +P   + I+ ++LH+ IR++   YA +++K+D+       +     D  +   I+ YK L+K AK   + K+   +  C+T+ T   V+   N+     ++DE  MC EPE LIP+ +  K +  VVL+GDHKQLRP + +R A K G++ S+FERY K       ML+ QYRMHP IC+FP+ +FYS
Sbjct:    1 QLNIMQTTVIKQSLTSAFTVIQGPPGTGKTVVGIHLVKWFHEVIKTLRENLQADAKHICSLYCGPSNKSVDVVAEHLV-KIEDLKP--LRVYGQQTEEEEFPIPGETDVIFLRSKKVPRVNLTIKSITLHYKIREDTNPYAQQIRKYDD------GQTEEVKDLTL-EEIIEYKKLIKDAKVIELKKSDVVITTCSTAAT---VILLKNLDPRVCLVDECAMCTEPECLIPLTSY-KDIAQVVLLGDHKQLRPFVLNRTAAKLGMEKSMFERYAK----RAIMLDTQYRMHPDICEFPAKQFYS 286

HSP 2 Score: 131.339 bits (329), Expect = 4.896e-32
Identity = 72/173 (41.62%), Postives = 111/173 (64.16%), Query Frame = 2 
Query: 5285 IFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCV 5803
            +F  V+G+E++  V+T  G+E SK NK EVE V  +  +L++      +A   I +LT Y+ Q + ++   +   +KK T +    T+ +SQGSE  YV+ STVRS ++++   NP+ GW+   LGFI + NQ+NVALTRAK+GL IIGN+ LL  +  WK+LIE+  E++C+
Sbjct:  317 LFGHVVGKEVTLVVSTEEGSENSKANKAEVEQVVRLVSELIKK---GSIAEKDIAILTPYNAQANEIQKALEKEHIKKVTAT----TITKSQGSEWRYVLLSTVRSCSLDEFKANPSRGWQISRLGFIIDENQVNVALTRAKEGLCIIGNQDLLMCSDLWKELIESYHEKDCL 482
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008661.1 (pep scaffold:Pmarinus_7.0:GL478401:184160:191851:-1 gene:ENSPMAG00000007841.1 transcript:ENSPMAT00000008661.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 142.124 bits (357), Expect = 6.550e-36
Identity = 82/218 (37.61%), Postives = 128/218 (58.72%), Query Frame = 2 
Query: 4391 KLLRIFGKEQEVSDFPIPGH----FFKNKTLP---IDIQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQ--VIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYS 5014
            K LR++G++ E  +FPIPG     F ++K +P   + I+ ++LH+ IR++   YA +++K+D   + ++        F    +   YK L+K AK   + K+   +  C+T+ T   V+   N+     ++DE  MC EPE LIP+ +  K +  VVL+GDHKQLRP + +R A K G++ S+FERY K       ML+ QYRMHP IC+FP+ +FYS
Sbjct:   25 KPLRVYGQQTEEEEFPIPGETDVIFLRSKKVPRVNLTIKSITLHYKIREDTNPYAQQIRKYDERIRILKK-------FRSMQS-KKYKKLIKDAKVIELKKSDVVITTCSTAAT---VILLKNLDPRVCLVDECAMCTEPECLIPLTSY-KDIAQVVLLGDHKQLRPFVLNRTAAKLGMEKSMFERYAK----RAIMLDTQYRMHPDICEFPAKQFYS 226

HSP 2 Score: 131.339 bits (329), Expect = 2.490e-32
Identity = 72/173 (41.62%), Postives = 111/173 (64.16%), Query Frame = 2 
Query: 5285 IFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCV 5803
            +F  V+G+E++  V+T  G+E SK NK EVE V  +  +L++      +A   I +LT Y+ Q + ++   +   +KK T +    T+ +SQGSE  YV+ STVRS ++++   NP+ GW+   LGFI + NQ+NVALTRAK+GL IIGN+ LL  +  WK+LIE+  E++C+
Sbjct:  257 LFGHVVGKEVTLVVSTEEGSENSKANKAEVEQVVRLVSELIKK---GSIAEKDIAILTPYNAQANEIQKALEKEHIKKVTAT----TITKSQGSEWRYVLLSTVRSCSLDEFKANPSRGWQISRLGFIIDENQVNVALTRAKEGLCIIGNQDLLMCSDLWKELIESYHEKDCL 422
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Sea Lamprey
Match: upf1 (UPF1 RNA helicase and ATPase [Source:ZFIN;Acc:ZDB-GENE-040426-2836])

HSP 1 Score: 123.635 bits (309), Expect = 2.160e-28
Identity = 119/417 (28.54%), Postives = 184/417 (44.12%), Query Frame = 2 
Query: 3803 GDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMN--KIDKIELLKEV---ILGAETNKKINNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVS 5038
            GD +CLR + E     W G GHV+ +     +   ++L      +SN  +P    + NF +D   KS    R Q  +    +D+  +   +   +LG E    +    + ++ +          N +Q  AVK  L + LSLI GPPGTGKT+    + +       K+N    VL C PS    N+    + EK +    K++R+  K +E  D P              +  ++LH  IR N     EL+K   +      KD      +       Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P    A   K ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+
Sbjct:  347 GDEICLRYKGE-LAAPWKGIGHVIKVPDNFGDEIAIEL------RSNTGVPAECTH-NFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVL---IKCMLPKRFTAPGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLA----KQNSGP-VLVCAPS----NIAVDQLTEKIHRTGLKVVRLCAKSREAIDSP--------------VSFLALHNQIR-NMDSLPELQKLQQL------KDETGELSSADEK--RYRALKRNAERELLMNA--DVICCTCVGAGDPRLAKMQYRSILIDESTQATEPECMVPTVLGA---KQLILVGDHCQLGPVVMCKKAAKAGLCQSLFERLVVLGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVT 714

HSP 2 Score: 64.6994 bits (156), Expect = 2.265e-10
Identity = 54/187 (28.88%), Postives = 86/187 (45.99%), Query Frame = 2 
Query: 5273 PERIIFIDVIG--EEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            P++ +F  V    EEI+ S T+         N+ E   V  I  +LL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRAK G+II+GN + L     W  L+   +E+  ++   LN
Sbjct:  730 PDKPMFFYVTQGQEEIASSGTSYL-------NRTEASNVEKITTRLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHAKLYQEVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRAKYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLN 892
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Sea Lamprey
Match: dis3l (DIS3 like exosome 3'-5' exoribonuclease [Source:NCBI gene;Acc:560362])

HSP 1 Score: 100.908 bits (250), Expect = 2.172e-21
Identity = 121/519 (23.31%), Postives = 202/519 (38.92%), Query Frame = 2 
Query: 1424 EYLFVVLYQKWNPHFMYPYG---RIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHIT-------------LPSGAIVFTIDNKTTKDMDDAISYHR-EMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANV-----DA-----------DLYMALESVYKIARKIRHARLPYSYF-VRSV---------KNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCS---LDIDEICVNANTKSKYNKNFEK 2842
            +Y  VV    W     YP G   R++G         +    + A+   N + + P  E +++      M +D P                L S  ++F++D    +D+DDA+S        + +GVHI+DVT ++ P S    +A+    T+Y   YL    + +    L+ +  SL+ G  R  VSV ++   +    K   +           VI S YKL+YE     L        V     DA           +L  AL  +  +AR +R  R       + SV         ++   +L  +   E    + E M+ AN +VAR + +  P   LLR   P   R E+ E L             + C      + + +S      ++   E  +  +  +D    K L           VH      +SN  Y++     +    H+ L    YTHFTSPIRR+ DV+VHR L +V+      + +    ++ E+C + N +++  +  +K
Sbjct:  389 DYRVVVRIDSWEATSQYPNGHFVRVLG------RAGELETEVAALLVENAISVLPFSEAQLR-----EMPVDSPETPWRMDGEEVARRCDLRSSHLIFSVDPPGCEDVDDALSVKTVAGGNLELGVHIADVTHFLRPHSHTDLEAR-VRATTY---YLADRRFDMLPSVLSGNLCSLLGGVDRYAVSVRWELDGDTYEVKRVWYG--------RTVIRSSYKLSYETAQALLDGGAAAQGVTIPELDAFDDGTRQERLRELVWALGRLTDVARAMRARRTEEGGLELESVEVRVQMSESRDSIADLVPQQPLEVHETVAECMIAANHWVARRVAQALPGRALLRHHPP--PRHEFFEEL-------------KACAAAMGFHIDTSS------NKALAESLDNAVDPNDPLINKML-------RSMAVHA-----MSNALYFSTGSLPADQHYHYGLALDHYTHFTSPIRRYADVMVHRQLLAVLEAKGAPETTPLNTELQELCEHINERNRAAQQVQK 851
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Sea Lamprey
Match: ighmbp2 (immunoglobulin mu DNA binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-050419-258])

HSP 1 Score: 93.2041 bits (230), Expect = 2.329e-19
Identity = 79/303 (26.07%), Postives = 140/303 (46.20%), Query Frame = 2 
Query: 4157 FNRNQYNAVKNALNQK-LSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKN---KFDMILCTTSVTLK----QVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERY-QKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVS 5038
             + +Q  AV  AL Q+ +++I GPPGTGKT      +     + +   +   VL C PSN  ++     ++E+      ++LR+ G    + D        +++ L   +       ++R      D     D +   +RN         +   + + +  +++ +++  ++N     D+IL TT+        +++   + A  ++DE G   E  + +P+  A +     VL GDH+QL P I S+ A + GL +SL ER  ++L    V ML +QYRM+ +I D+ S   Y GKL  H S
Sbjct:  195 LDHSQREAVIFALAQREVAIIHGPPGTGKT------TTVVEIIQQTVRRGEKVLACAPSNVAVD----NLVERLACAGVRVLRL-GHPARLLDS------VRSRCLDAVLARGDDAGIVR------DVRSDMDKVHAKLRNGSERGERARLQAEMRSLRKELRE-REDTAMRNILQSADVILATTTGAWAGGPLKLLPPAHFAVAVVDECGQAVEAASWLPLLQAPR----CVLAGDHRQLPPTIVSQRAAEGGLAVSLMERLVERLGSSAVRMLTVQYRMNAAIMDWASQHVYQGKLEAHPS 469
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Yeast
Match: NAM7 (ATP-dependent RNA helicase of the SFI superfamily; involved in nonsense mediated mRNA decay; required for efficient translation termination at nonsense codons and targeting of NMD substrates to P-bodies; binds to the small ribosomal subunit via an interaction with Rps26; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000004685])

HSP 1 Score: 169.088 bits (427), Expect = 1.173e-42
Identity = 167/568 (29.40%), Postives = 250/568 (44.01%), Query Frame = 2 
Query: 4145 NWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILT--YKNLVKKAKKEYIVKNKFDMILCT-TSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPER---IIFIDVIG-EEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQH--LLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            N+ + N +Q NAV + L + LSLI GPPGTGKT+    + +  + +++       +L C PSN  ++ +A+    K  +   K++R+  K +E               +   +  ++LH L+ +  G   ELK   N+ K    KD +       +A  T  +  LV+K + E +  NK D++ CT      K++ T F    V+IDE+    EPE LIPI    K  K V+L+GDH+QL P+I  R A   GL+ SLFER   L   +   L +QYRM+P + +FPS  FY G L                                    NG+  E+                +P++K+P                +P R   ++F    G EEIS        N  S  N++E      I  KL    F   + P  I V+T Y  Q+   L  M+    L K       V +V   QG E DY+I S VR+              EQ+ +GF+ +  ++NV LTRAK GL+I+GN R L  N  W  L+ +  E+ C++   L+
Sbjct:  405 NFAQLNSSQSNAVSHVLQRPLSLIQGPPGTGKTVTSATIVYHLSKIHKDR-----ILVCAPSNVAVDHLAA----KLRDLGLKVVRLTAKSRE--------------DVESSVSNLALHNLVGR--GAKGELK---NLLKL---KDEV----GELSASDTKRFVKLVRKTEAEIL--NKADVVCCTCVGAGDKRLDTKFRT--VLIDESTQASEPECLIPI---VKGAKQVILVGDHQQLGPVILERKAADAGLKQSLFERLISLG-HVPIRLEVQYRMNPYLSEFPSNMFYEGSL-----------------------------------QNGVTIEQ--------------RTVPNSKFP----------------WPIRGIPMMFWANYGREEIS-------ANGTSFLNRIEAMNCERIITKL----FRDGVKPEQIGVITPYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAFQGREKDYIILSCVRAN-------------EQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSLARNTLWNHLLIHFREKGCLVEGTLD 840
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Yeast
Match: HCS1 (Hexameric DNA polymerase alpha-associated DNA helicase A; involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities [Source:SGD;Acc:S000001500])

HSP 1 Score: 117.087 bits (292), Expect = 7.152e-27
Identity = 157/585 (26.84%), Postives = 249/585 (42.56%), Query Frame = 2 
Query: 4157 FNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPK--LLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIF---KCIRNKDPIPPDFNVYNAILTYKNLVK---KAKKEYIVKNKFDMILCTT--SVTLKQVVTFFN-------IAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADK---RGLQISLFERYQKLKP--ELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTT--GNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQ-QHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLL-----KVNQTWKKLI-ENLEERNCVIADYL 5818
             N +Q  A+  A+N  L++I GPPGTGKT     L       N +E     +L CGPSN  ++    T++E+     P   LLRI G    + D         NK   +DI       L +KN    D  ++ D +    K ++N      ++N     L  K+L K   K  K+ I++++   I+ TT    + +++ + +           +IIDE     EP+  IP+ A       +VL GD+KQL P I++   DK     L+ +LF+R  K+ P  ++V  LN+QYRM+  I +FPS   Y+GKL+   +                          + I+   +D   S D               D K P                    +I+ D  G+E  ++    T  G   SK N+ E+ +V    K+ +E      +  N I V++ Y+ Q  HL ++    + L    T   + TV   QG E D +I S VRS              E+  +GF+    ++NVA+TR ++ L+++GN  +L     K  ++W +   EN + R   I DYL
Sbjct:  208 LNDSQKTAINFAINNDLTIIHGPPGTGKTFTLIELIQQLLIKNPEER----ILICGPSNISVD----TILERLTPLVPNNLLLRI-GHPARLLD--------SNKRHSLDI-------LSKKNTIVKDISQEIDKLIQENKKLKNYKQRKENWNEIK--LLRKDLKKREFKTIKDLIIQSR---IVVTTLHGSSSRELCSLYRDDPNFQLFDTLIIDEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTE-DDKNVIHNLETTLFDRIIKIFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATV----------------------ANRLLIDLPTVDATPSEDD-------------DDTKIP--------------------LIWYDTQGDEFQETADEATILG---SKYNEGEIAIV----KEHIENLRSFNVPENSIGVISPYNAQVSHLKKLIHDELKL----TDIEISTVDGFQGREKDVIILSLVRSN-------------EKFEVGFLKEERRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWSEWCEENADVRYPNIDDYL 683
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Yeast
Match: DIS3 (Exosome core complex catalytic subunit; has both endonuclease and 3'-5' exonuclease activity; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; role in degradation of tRNAs; similar to E. coli RNase R and to human DIS3, which partially complements dis3-81 heat sensitivity; mutations in Dis3p analogous to human mutations implicated in multiple myeloma impair exosome function; protein abundance increases under to DNA replication stress [Source:SGD;Acc:S000005381])

HSP 1 Score: 109.383 bits (272), Expect = 3.366e-24
Identity = 107/402 (26.62%), Postives = 173/402 (43.03%), Query Frame = 2 
Query: 1661 IVFTIDNKTTKDMDDAISYHREMN-QIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSY-PPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAEL----------LIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLD---IDEICVNANTKSK 2821
            ++ +ID     D+DDA+   +  N    +GVHI+DVT +V P + +  +      + Y   K +++ P       L TD  SL P   R   SV+++  ++         ++IV   F + VI S+   +YE+  L +   DD    D +L M + ++ K++ K++  RL       +      ++ +E     E+          L+EEFMLLAN  VAR IY+ +P + +LR  +              STN               +LN   N+R+   +S +  +   + +        +C+   D YFN   V I     +    Y+        +  H+ L   +YTHFTSPIRR+ DVV HR L   I    +     D   +D IC N N K +
Sbjct:  538 LICSIDPPGCVDIDDALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARGTSVYLVDKRIDMLPML-----LGTDLCSLKPYVDRFAFSVIWELDDS---------ANIVNVNFMKSVIRSREAFSYEQAQLRI---DDKTQND-ELTMGMRALLKLSVKLKQKRLEAGALNLASPEVKVHMDSETSDPNEVEIKKLLATNSLVEEFMLLANISVARKIYDAFPQTAMLRRHA-----------APPSTNFE-------------ILNEMLNTRKNMSISLESSKALADSLD-------RCVDPEDPYFNTL-VRIMSTRCMMAAQYFYSGAYSYPDFRHYGLAVDIYTHFTSPIRRYCDVVAHRQLAGAIGYEPLSLTHRDKNKMDMICRNINRKHR 889
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Yeast
Match: ECM32 (DNA dependent ATPase/DNA helicase; helicase belonging to the Dna2p- and Nam7p-like family of helicases that is involved in modulating translation termination; interacts with the translation termination factors, localized to polysomes [Source:SGD;Acc:S000000978])

HSP 1 Score: 91.2781 bits (225), Expect = 1.026e-18
Identity = 95/330 (28.79%), Postives = 141/330 (42.73%), Query Frame = 2 
Query: 4154 KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFA-----YTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFG--KEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAK--KEYIVKNKFDMILCTTSVTLKQVVTFFNIAQ-------------VIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERY---QKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKL---ITHVSPLWCGLK 5059
            K NR+Q  AV++ LN  ++++ GPPGTGKT     +        + F          +L    SN  I+ +A  +ME  N    K+LRI    KEQ+ SD    G             E+ LH ++ KN                      + PD  V         ++ K++  K Y  KN+    +    V+  Q++   NIA              VI+DEA    E  TL+P++     ++N V +GD KQL     S  ++   L+ SLFER       K  L  ML+ QYRMHP I +FP  + Y+G+L   +T     W G++
Sbjct:  648 KLNRSQKTAVEHVLNNSITILQGPPGTGKTSTIEEIIIQVIERFHAF---------PILCVAASNIAIDNIAEKIME--NRPQIKILRILSKKKEQQYSDDHPLG-------------EICLHNIVYKN----------------------LSPDMQVVANKTRRGEMISKSEDTKFYKEKNR----VTNKVVSQSQIIFTTNIAAGGRELKVIKECPVVIMDEATQSSEASTLVPLSLPG--IRNFVFVGDEKQL-----SSFSNIPQLETSLFERVLSNGTYKNPL--MLDTQYRMHPKISEFPIKKIYNGELKDGVTDEQKAWPGVQ 918

HSP 2 Score: 60.4622 bits (145), Expect = 3.086e-9
Identity = 47/141 (33.33%), Postives = 67/141 (47.52%), Query Frame = 2 
Query: 5429 LAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPI------------VKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLL-KVNQTWKKLIENLEERNCVIAD 5812
            L  N +    Q S QQ   E+E  +    + T   +            V TV   QG E  ++IFS VR+ N E+             +GF+ +  ++NVALTRAK GLI++GNK +L K +  WK  I  LEE+  +  D
Sbjct:  990 LTKNVVINPKQISMQQEYDEIELFNAAGSQGTAGSLQNNVINIINGLHVATVDSFQGHEKSFIIFSCVRN-NTEN------------KIGFLRDKRRLNVALTRAKHGLIVVGNKNVLRKGDPLWKDYITYLEEQEVIFTD 1117
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Yeast
Match: SEN1 (ATP-dependent 5' to 3' RNA/DNA and DNA helicase; subunit of the exosome-associated Nrd1p complex that mediates 3' end formation of snRNAs, snoRNAs, CUTs and some mRNAs; helicase-independent role in transcription-coupled repair; coordinates replication with transcription, associating with moving forks and preventing errors that occur when forks encounter transcribed regions; homolog of Senataxin, implicated in Ataxia-Oculomotor Apraxia 2 and a dominant form of juvenile ALS [Source:SGD;Acc:S000004422])

HSP 1 Score: 86.2705 bits (212), Expect = 5.282e-17
Identity = 98/362 (27.07%), Postives = 152/362 (41.99%), Query Frame = 2 
Query: 4106 PTEKIIAQIENELNWKKFNRNQYNAVKNALNQK-LSLIWGPPGTGKT-----MVGCYLSF----AYTFVNRKENKNSV----------VLYCGPSND-----CINLVASTMMEKFNEKCPKLLRIFGKE-----------QEVSDFPIPGHFFKNKTLP--------IDIQEVSLHFLIRKNGGYADELKKFDNIFKC---IRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNK-------FDMILCTTSVTLKQVVTFFNIA--QVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKL 5023
            P     A+IE      K N +Q  A+ N+++++  SLI GPPGTGKT     ++G +LS     +   +     KNS           +L C PSN      C+ L +    ++ ++  P+L+R+   +           +E+ D  I    ++ +T P           +   L   +    G  +     ++I K    IR    I  +       +  KN V    ++   +N         D+I  T S +   V+    I    VIIDEA  C E  ++IP+    K     +++GD  QL P + S  A       SLF R +K       +L++QYRMHPSI  FPS EFY G+L
Sbjct: 1318 PVNVDAAEIETVKKSYKLNTSQAEAIVNSVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSNVIKVPLEKNSSNTEQLLKKQKILICAPSNAAVDEICLRLKSGVYDKQGHQFKPQLVRVGRSDVVNVAIKDLTLEELVDKRIGERNYEIRTDPELERKFNNAVTKRRELRGKLDSESGNPESPMSTEDISKLQLKIRELSKIINELGRDRDEMREKNSVNYRNRDLDRRNAQAHILAVSDIICSTLSGSAHDVLATMGIKFDTVIIDEACQCTELSSIIPLRYGGK---RCIMVGDPNQLPPTVLSGAASNFKYNQSLFVRMEKNSSPY--LLDVQYRMHPSISKFPSSEFYQGRL 1674

HSP 2 Score: 58.9214 bits (141), Expect = 1.057e-8
Identity = 42/173 (24.28%), Postives = 82/173 (47.40%), Query Frame = 2 
Query: 5288 FIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETC-FPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCV 5803
            F D+I     Q+  T +     +  +V +E+V Y+++K      F  +     I +++ Y  Q   +  E           S    T+   QG E + ++ S VR+ +             +  +GF+ +  ++NVALTRAK  + ++G++R L  ++ W+ LIE+ ++R+C+
Sbjct: 1699 FFDIISGRQEQNAKTMSYTNMEEI-RVAIELVDYLFRKFDNKIDFTGK-----IGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGFQGQEKEIILISCVRADDT------------KSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDLIEDAKDRSCL 1853
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Nematostella
Match: EDO45137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTS2])

HSP 1 Score: 246.514 bits (628), Expect = 3.004e-65
Identity = 329/1393 (23.62%), Postives = 555/1393 (39.84%), Query Frame = 2 
Query: 1079 GKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHV---ENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIV-IGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWL--KQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRF----EAELLIEEFMLLANEYVARIIYE--KYPNSTLLRMQSPVKNR--EEWLENLHESTNLNFAGQLKEYCNLLGVLNFN---RNSRQKFIVSRKFFELFNEFIKQSDFDK-AKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPL--------LQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPK---SAENVNFTLDIYQKS---IVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIENELNWK---KFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVS------LHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVV-TFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTM---LNLQYRMHPSICDFPSMEFY---------SGKLITHVSPLWCGLKSDHMKVFCHSSD 5095
            GKV+ + +  H    + Y+C       N+M P++   P++ V   +N  GR                                  T F++F++            G  +  +F  +    LF+V   +W   F YP G +        SL+ +LP+  A   L L+         +    E   I D    +    +   TID   T ++DDA+S     N +V +GVH++DV+ ++S  S   + A     ++YP     I   ++  E+L     SL+PGK R  +SV+F F        N +   +  PE R  ++ SKY L +++    L  + S+ P +V   +++    +  ++RK+        Y +R+ + C   L    R     ++  ++E+ M+ AN  VA  + +  +  + T LR QSP K+   + W      S     AG L E    L  +  N   +N+     V        +  I   D     + L ++D        H           Y   S+      GHF+L    YTHFTSP+RR+ D+VV R+L +V+   ++   + ++++IC    T       FE+ C+   +    +       + V   +  ++I  + P         L + + D +    + S+DE  VLS   + F      W       PP+  S SS +  F++ + L+ S++     +    I       +AL NK+       +           +    +P       +   + +R+         ++Q   +   V    + C +H + P+K F        L      S+SS +EY+   +PL+E E     LSD S  TL +                     +TLS  F  + SD     + ++  R   L   G     GD LC+R R+ +          V       +    + + I R       LP     A N    +++  +S      I+    +++I K   LKEV+LG            KI+A+ + E N +     + +Q +AV+ AL   L++++G PGTGK+     ++  +   NR +    V+L C P+   +++V+  +++    +    +RI+ K+ E +     GH   N  L + ++  S      L     +      EL    +  K  R +  +      YN IL        A+   + +   D+I+CT +    Q + T  NIAQ I+DE+  C EPE L+P   A       VL+GDHKQL P+++S+ A K GL  SLFE   +   E  +    LN Q+RMHPS+  F S  FY         S      +   W   + D   VFCH  D
Sbjct: 1448 GKVVSIVEEIHP---RQYLCIADSLDTNIMTPINSVNPRVVVLQSKNPQGR----------------------------------TGFAVFELKD----------GESQLRDFVTEAQGKLFLVQVMEWGASFRYPLGIVRQCFQEVTSLETALPVFAADNGLQLVP------ARMGGFNEDWTIPDTEWGSRLHFSEALTIDCGKTMELDDALSVKAGANGVVSVGVHVADVSYFISKDSSFDQAAFAQGTSAYPTDGSGIA-VNMLPEQL-RRLCSLLPGKHRLAISVIFTF--------NTQGRSLRLPEVRRSIVSSKYSLTFDQCDAVLNGQASELPESVKRYIHV----LGSMSRKL--------YSLRTRQGCLAGLLDAVRATTFSKSSQIVEQLMIFANTAVAEKLLKSGRTKDLTPLRTQSPPKSHILQSW------SLACERAGILPESSLTLRRVASNPSSQNTPSTVSVKVDLLGKISTAINAKDITLLTESLAEFDTDGRALEAHCRLSSLQERSQYVLSSKVGPAGYGHFTLGLDAYTHFTSPLRRYFDIVVQRMLVAVMLDEELPYTADELEQICSRCQTSKVQADTFERSCKLTNLAAGLSSSPQWT-EVVVHRVTPDKIRVSLPSASHSKKLSLTIRTQDLKPSDTDASMDEELVLSWDVQEFSCGPSSW-------PPHSRSHSSTERCFELPATLWCSFVSAVAREDVNRI-------QALWNKIPN--EGHILNEKPPTSPEMTSRSGQPFKRFTKHIKAGDRLRVVMGSTVLKSVLQPVIQGVQVLEDVYRCTVHMHVPAKCFGFPRASPTL-----TSYSSAEEYRGVMQPLLELEEATCCLSDGSRSTLLRG--------------------VTLS--FGRVVSDRVDSTM-RLPRRV--LSPGGRHVQAGDYLCIRPRRPNRRGQRSSGSSVFHARVHHVEGASIHVDIPRA-----GLPSVLIEAGNCECDIEVTPRSENHRQMIKAVCSLSRISKA--LKEVVLG-----------RKILAR-QCETNMRVVPGLDDDQAHAVRTALTHPLTMVYGQPGTGKSWTAVAIACHFVNQNRADAAGHVLL-CAPTERALDVVSELLLQVPGIRA---VRIYSKQAETTVIDGSGH--SNLALHMRVRHASNPHSKALLSCEAEISRLTQELTSCTDPTKQERTQHKLDSKRQKYNTILA------TAEGFELGETPVDIIICTCAEAGSQRMRTHANIAQCIVDESNYCLEPEVLVPAVTAGPRCSRFVLVGDHKQLVPVLQSKEAWKLGLGRSLFEDLWEAHREGSSACCTLNTQHRMHPSLGKFSSSFFYNVQQSRENVSNACARELEGFWPAGR-DLYHVFCHVED 2680

HSP 2 Score: 61.6178 bits (148), Expect = 3.747e-9
Identity = 48/157 (30.57%), Postives = 74/157 (47.13%), Query Frame = 2 
Query: 4601 NVYNAILTYKNLVKKAKKEYIVKNKFDM--------ILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQL-----RPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITH 5032
            +V + +L Y  L+ +    + + ++ D+         L T  V +K  +     + V IDEA    E ETLIP+    +S + +VL GDH Q+      P+ R RL   R L + L+E Y +     + +L   YR +  I + PS  FY G LI H
Sbjct:  550 SVSHTVLKY-CLIDRETGRFAIPSRQDIDCVSVIVTTLVTADVLVKMGLPSGYFSHVFIDEAAQAMEAETLIPLCLTQQSTR-IVLAGDHLQMGAHVFSPVAR-RLCLDRSLLVRLYELYPRESDSKLLLLE-NYRAYNDIVEIPSKLFYEGTLIAH 702

HSP 3 Score: 61.2326 bits (147), Expect = 6.151e-9
Identity = 32/88 (36.36%), Postives = 53/88 (60.23%), Query Frame = 2 
Query: 5558 QGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI--ADY 5815
            QG++ D ++ STVR    + +   P  G+     G + + +Q+NV LTRA+KGL+I+GN+  L  N  W +L+ + E  +CV+  AD+
Sbjct: 2755 QGAQCDVLVLSTVRGRPRDQLT-GPHGGF-----GCLGDKHQMNVVLTRARKGLVIVGNRYYLSGNPMWNRLLHDYEVLDCVVEAADW 2836
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Nematostella
Match: EDO31025 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZ42])

HSP 1 Score: 188.734 bits (478), Expect = 5.765e-53
Identity = 136/388 (35.05%), Postives = 188/388 (48.45%), Query Frame = 2 
Query: 4679 DMILCTTSVTLKQVVTFF--NIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAI----PDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNF--ITVLTQYSYQQHLLEMECKSILLKKTTTSPI----VKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            ++ILCT S +    +     NI QVI+DE GMC EPETL+PI  A    K VVLIGDHKQL+P+I+   A + GL+IS+FERY K       ML  QYRMH  IC FPS +F                                                    Y + L TS   A+    P   WP       Q  H++  + P   +F  V G E S  + T   N  SK N+ E     ++ K L+      + A N   + +LT Y  QQ         +L+K+   +P     V T+I+SQGSE DYVI S VRS+  ++I   P+  W   +LGF+ + +QINVALTRA++GL IIGNK L++++ TW  L+ + E+   ++
Sbjct:    1 EIILCTCSASGADRIVDLCDNIQQVIVDECGMCFEPETLVPITCA--RAKQVVLIGDHKQLQPIIKDNDAKRLGLEISMFERYAKK----AIMLKEQYRMHAEICHFPSEQF----------------------------------------------------YDKLLLTSATVALRTPSPVDFWPA------QVLHRK--DVPR--VFCHVEGCEKSSVIKTQYSNHGSKSNEKEANKAVHVAKVLVN-----KYAVNHGDVVILTPYRQQQ---------VLIKEGLHAPYDDIQVSTIIKSQGSEWDYVILSLVRSLPKDEIEAEPSSKWLGDNLGFLRDEHQINVALTRARRGLCIIGNKNLVELDPTWSALLSHYEQGETIV 306
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Nematostella
Match: EDO31024 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZ41])

HSP 1 Score: 113.235 bits (282), Expect = 3.202e-27
Identity = 63/130 (48.46%), Postives = 76/130 (58.46%), Query Frame = 2 
Query: 4733 NIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVS------------PLWCGLKSDHMKVFCH 5086
            NI QVI+DE GMC EPETL+PI  A    K VVLIGDHKQL+P+I+   A + GL+IS+FERY K       ML  QYRMH  IC FPS +FY   L+T  +            P      +D  +VFCH
Sbjct:    1 NIQQVIVDECGMCFEPETLVPITCA--RAKQVVLIGDHKQLQPIIKDNDAKRLGLEISMFERYAK----KAIMLKEQYRMHAEICHFPSEQFYDKLLLTSATVALRTPSPVDFWPAQVLYGNDVPRVFCH 124

HSP 2 Score: 107.071 bits (266), Expect = 5.036e-25
Identity = 66/180 (36.67%), Postives = 103/180 (57.22%), Query Frame = 2 
Query: 5285 IFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNF--ITVLTQYSYQQHLLEMECKSILLKKTTTSPI----VKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVI 5806
            +F  V G E S  + T   N++SK N+ E +   ++ K L+      + A N   + +LT Y  QQ         +L+K+   +P     V T+I+SQGSE DYVI S VRS+  ++I   P+  W   +LGF+ + +QINVALTRA++GL IIGNK L++++ TW  L+ + E+   ++
Sbjct:  121 VFCHVEGCEKSSVIKTQYSNQQSKSNEKEAKKAVHVAKVLVN-----KYAVNHGDVVILTPYRQQQ---------VLIKEGLHAPYDDIQVSTIIKSQGSEWDYVILSLVRSLPKDEIEAEPSSKWLGDNLGFLRDEHQINVALTRARRGLCIIGNKNLVELDPTWSALLSHYEQSETIV 286
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Nematostella
Match: EDO42429 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1B6])

HSP 1 Score: 114.775 bits (286), Expect = 1.468e-25
Identity = 111/405 (27.41%), Postives = 180/405 (44.44%), Query Frame = 2 
Query: 1664 VFTIDNKTTKDMDDAISYHREMNQIV-IGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVS--------LWLKQSDDPANVDADLYMALESV---YKIARKIRHARLPYSYFVRSVKNCYTNLQTENRF----------EAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKID-IDDCSLDIDEICVNAN 2809
            VFTID  T +D+DDA+   R  + ++ +GVHI+DV+ +V   + +   A++   ++Y  + + +P   +   +L  +  SL P + R   SV++  ++      ++K   I++         S+ K+ YE            W      P     D+   ++ V    KIAR++R  R               +L  E             E+  LIEEFMLLAN  VA  IY+ +P+  LLR     K  E+ +E+L             E C  LG+  +N NS +   VS          + Q     A+         +E  V +T    + N  Y+     +    GH++L+  LYTHFTSPIRR+ DV+VHRLL + +   + +D  ++D+D I  + N
Sbjct:  296 VFTIDPLTARDLDDALHCKRLSDGLIEVGVHIADVSFFVKTGTPLDDIAQERATSTYMVQTV-VP---MLPRRLCEELCSLNPDEDRLTFSVVWIMTDQGEIKSDWKGRGIIR---------SRVKMAYEHAQEMIDKPNKKWSDSELPPIAEGTDVSEIVKRVNLLAKIARQLRRNRFENGALRLDQVKLQFDLDKETGMPIGYHVYQQRESNKLIEEFMLLANMTVAHHIYKAFPDMALLRRHP--KPHEKQMEDL------------LELCRNLGI-KYNANSSKSIQVS----------LAQFPSGSAQ---------HEILVQLT-MKPMKNALYFCAGTVEEEEYGHYALSVPLYTHFTSPIRRYADVIVHRLLAASLELAEPLDKDAVDVDSIAGHCN 652
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Nematostella
Match: EDO34496 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP82])

HSP 1 Score: 108.612 bits (270), Expect = 5.275e-24
Identity = 135/546 (24.73%), Postives = 208/546 (38.10%), Query Frame = 2 
Query: 4211 LIWGPPGTGKTM--VGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAK----SVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFER-------YQKL-----------KPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLI 5776
            LI+GPPGTGKT+  V       + F N K      VL C PSN   +L+   +M                              K+  +P  ++ + L+   R     +D +K    +  CI + D   P                  K+E + K      L T    +   +   +   V IDE+G   EPE ++P+A            +VL GD +QL P++RS LA K GL++SL ER       Y ++           +P ++T L   YR HP+I + P+  FY  +L T      C               + K K E   NW                     + +P   +P                    I+F  V+G+++ +  + +  N +         VV +I  K L      R+    I V++ Y  Q      + + +L K   T   V +V   QG E   +I STVRS   E +  +  F      LGF+ N  + NVA+TRA+  LI++GN  +L  +  W + I
Sbjct:   86 LIFGPPGTGKTITVVESIKQVLHVFPNSK------VLACAPSNSAADLILERVM------------------------------KHNVIP-KMKMLRLNAFGRSYASLSDSIK----VVSCIHDGDFFFP-----------------GKEEIMNKRLVVCTLVTAGRLVSADIPDTHFTHVFIDESGQALEPECMVPLAGLLNPENPGGGQLVLAGDPQQLGPVLRSPLAIKYGLRMSLLERLMTRVAAYGRITEDEEDELGEYEPAMLTKLLKNYRSHPAILELPNGMFYDDELET------C---------------ADKLKRESLCNW---------------------SKLPTKGFP--------------------ILFDGVLGKDLREGKSPSFFNPEEAAT-----VVKHI--KDLRDSRGVRVLMAEIGVISPYRQQVS----KIRQLLHKNNITGIKVGSVEEFQGDERRVIIISTVRSSQ-EFLKMDAQF-----KLGFLNNRKRFNVAITRAQALLIVVGNPHVLCKDSHWGRFI 494
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Medaka
Match: ENSORLT00000013379.2 (helicase with zinc finger 2 [Source:NCBI gene;Acc:101162116])

HSP 1 Score: 306.99 bits (785), Expect = 2.362e-83
Identity = 338/1306 (25.88%), Postives = 560/1306 (42.88%), Query Frame = 2 
Query: 1430 LFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSR----------QKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYY-NCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVN---ANTKSK-YNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPL-LQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRK---------------IIFSCPPYLNSSSS--NDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIH-----------QNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCN-LRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNY-------------WVGHGHVVTINKCMINNQKM----KLIIFRLTQSNFDLPKS--AENVNFTLDIYQKSIVSIRQQ-VIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIENELNWKKF-------NRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRK------------ENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHF--FKNKTLPID-----IQEVSLHFLIRKNGG-YADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCT-TSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERY-QKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSD 5065
            +FVV    W     YP GR+   L   D          A+ +    E++   EK+V   R+                I FT+D    +D+DDAIS     N   + +HISDV  +V   S++   A+    T Y        P H+F E L+T   SL+ G+   V+S++F+  +          S + +P F   +I S  +L+YEE    + +     +    +   L + Y  A+  R  RL    + +S  +     +   R +A L+IEE  +L N++ +    E   +S   R+ +P++ ++E         + +   + KE C  L  L+F+   +          + F V  K +       +++D DK   L+  D+        I  +   SN SY    S      +GH+SLN   YT  +SPIRR+ D+++ RLL  V+   D       I  +C     + TK++ Y +  E+L    +   +++ +  LI   V ++   +      P  + V      I +A+L L++ P+ ++ N       L W+K                I  C P +    +   D    I++   D     + S L Q      ++ +  EN + Q  T     +  +     S    E   +++L +   + +++Q    K  G      +L  +   F IC+ H            N+PS++F                +++I +YK+ ++PL E ES   A+ D  +  +E +                    I+ S   C+ L    F  E++     +E+       S+    LC+R R  +                 WV HG    + +   + +K+       I  L   N  +PK     N  FT++I  K +  IR++  ++N     +L+K +IL     K+I  P  +  + +  ++  KK        N +Q  AV  A+N+  +LI GPPGTGKT+VG Y+   +  +N K             NK  V+LYCGPSN  +++VA  +M   +    +LLR++    E+ D+P P     F  KTL  D     ++ ++LH  +R+N   +AD+++KFD   +  RN+D           I  YK+L+KKA+   +   + D+ILCT T  +   +    +  Q++IDE  M  EP+ LIP+       + VVLIGDHKQLRP++++    K G+  SLFE Y  +L  +   ML+ QYRMH  IC+FPS +FY GKL T V P    L+ D
Sbjct: 1522 IFVVQVLGWKKQCFYPIGRVTDILPESDDELLKKEFGVAVPSYESFELT---EKDVTERRDDL-----------RSTITFTVDPPDAQDLDDAISVKDLGNIYELEIHISDVASFVGANSDLDSYAEKRGSTYY---NRGKKPTHMFPEDLSTGCFSLLSGQDCRVISLMFRVEKET-------HSILEKPTFHLSLINSDKQLSYEEAEKIITERYTERSRFDTVEDCLTAAYCFAKTQRRTRLKDWAYSQSDDD-----RLPGRRKAHLMIEELSVLYNKHAS----EYLTDSMKTRLCTPLRCQKE--------PDPDKVEEFKEKCKHLIPLSFHVKPKVPIDEPTQRLEGFQVLTKVWTCIQAAARENDLDKMVDLVAADDIHPLLQPVINQFKRCSNKSYVIRSSSCKEATVGHYSLNIKYYTQASSPIRRYMDIILQRLLHCVMCDKDCQYTRNQITAMCSQFQESLTKARAYEQKAEELAFTVSTRHQSSPKLALI---VHTDKEGDGFEVTFPFNMSVFHRTMSIMYADLQLEDQPLFNEVNHAV---TLTWKKRIYIAESSNVQLNLNTILDCGPCVKIPLAVWRDAMEAIENQDLDC----AKSLLLQ------VNTQPWENPMLQPPTPLSKTSACSTEKKLS----ESWTNVDLQLQPGDRLQVQMTSEKRRGYHMPTIQLVHIKKHFEICIDHVHRPVVCFSKPSNDPSRYF----------------YNNINQYKEIWKPLCEMESASTAVDDCESVIIEDL-------------------EISFSQTQCDKLTGTFFLPELWT--REFEF-------SLRHCFLCIRKRNLELTAASEFSTQVDPTQFTWVAHGVTSYVEEKEKDQKKVGSKVDFFINHLPMEN--IPKCIFQSNTCFTVEIIPKLLPDIRKEGAVVNLEKACDLVKSIIL----RKRIKTPVVQY-SMLRFQVKRKKLPGDLPELNDSQSQAVTTAINEPFTLIQGPPGTGKTVVGVYIVHWFLEMNSKTPRIFDDPYDEHRNKKEVILYCGPSNKSVDVVAEYLMRLKDSL--RLLRVYSHHVEMLDYPYPDSTLQFSPKTLRQDRSKPELRSITLHHRMRENPNPHADDIRKFDERIR--RNED------FTQKEIEEYKDLLKKARVHEL--EQHDIILCTCTQSSTPSLSRSVSARQILIDECAMATEPQALIPLVC--NKPEKVVLIGDHKQLRPIVKNESVKKLGMSRSLFESYFNQLSEKKAVMLDTQYRMHEDICEFPSEKFYEGKLKTAVEPAASVLRVD 2701

HSP 2 Score: 112.464 bits (280), Expect = 4.825e-24
Identity = 69/174 (39.66%), Postives = 98/174 (56.32%), Query Frame = 2 
Query: 5282 IIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCV 5803
            ++F D+ G  I   V T+ GN  SK N  E + V  I   L+      ++    I VL+ Y+ Q   +  E     LK+ T    V T+ +SQGSE  YVI STV S++ ++I   P  GW  KH+GF+ + NQINV +TRAK+GL IIGN++LL  + TW+ L+ +   RN V
Sbjct: 2707 VVFGDIEGVTIKLVVKTSKGNNNSKANYEERDQVVRIVTMLVNKA---KVEQRSIVVLSPYNAQVSEIREELGKNNLKQIT----VTTITKSQGSEWRYVILSTVCSLSSKEIVREPDGGWLSKHIGFVGDPNQINVGITRAKEGLCIIGNQKLLACSSTWRALLAHYRCRNAV 2873
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Medaka
Match: UPF1 (UPF1 RNA helicase and ATPase [Source:NCBI gene;Acc:101168695])

HSP 1 Score: 165.236 bits (417), Expect = 1.734e-40
Identity = 195/775 (25.16%), Postives = 311/775 (40.13%), Query Frame = 2 
Query: 3539 EYKDYFEPLIEDESLMEALSDR---SAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMN--KIDKIELLKEV---ILGAETNK---KINNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPID-IQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLL--EMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +Y++ F PL++    +EA  D+    + T + + ++W LG + K     R    TL     ++R                         + GD +CLR  K D    W G GHV+ +     +   ++L      +S+   P    + NF +D   KS    R Q  +    +D+  +   +   +LG E      K   P ++  AQ          N +Q  AVK  L + LSLI GPPGTGKT+    + +  +        N  VL C PSN    +    + EK ++   K++R+  K +E  + P+      N+   +D + E+     ++   G   EL   D                        Y+ L + A++E ++    D+I CT        +       ++IDE+    EPE ++P+   AK    ++L+GDH QL P++  + A K GL  SLFER   L    +  L +QYRMHP++  FPS  FY G L   V+                ++D  KK         G D++                      WP   K  F               ++    EEI+ S T+         N+ E   V  I  +LL+        P+ I ++T Y  Q+  L   M+    L  K      + +V   QG E D++I S VR+              E + +GF+ +  ++NVALTRAK G+II+GN + L     W  L+ N +E+  ++   LN
Sbjct:  282 QYQNIFGPLVK----LEADYDKKLKESQTQDNITVRWDLGLNKK-----RIAYFTLPKTDSDMRL------------------------MQGDEICLR-YKGDLAPLWKGIGHVIKVPDNYGDEIAIEL------RSSVGAPVEIPH-NFQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVTIKCQLP-KRFTAQ-----GLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLS-----RQGNGPVLVCAPSN----IAVDQLTEKIDKTGLKVVRLCAKSREAIESPVSFLALHNQISNMDSMPELQKLQQLKDETG---ELSSADE---------------------KRYRALKRTAERELLMNA--DVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAK---QLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPI-RLQVQYRMHPALSAFPSNIFYEGSLQNGVT----------------AADRIKK---------GFDFQ----------------------WPQPDKPMF--------------FYVTQGQEEIASSGTSYL-------NRTEAANVEKITTRLLKAG----AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQQVEIASVDAFQGREKDFIILSCVRAN-------------EHQGIGFLNDPRRLNVALTRAKYGVIIVGNPKALSKQPLWNNLLNNYKEQKVLVEGPLN 885
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Medaka
Match: dis3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease [Source:NCBI gene;Acc:101166822])

HSP 1 Score: 114.39 bits (285), Expect = 5.826e-25
Identity = 102/377 (27.06%), Postives = 174/377 (46.15%), Query Frame = 2 
Query: 1664 VFTIDNKTTKDMDDAISYHREM--NQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYP-PKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHAR----------LPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQ-SPVKNREEWLENLHESTNLNF-AGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVI 2749
            V ++D     D+DDA+ + RE+    + +GVHI+DV+ ++ P + + K+A +   T Y   K +++ P     E L+++  SL     R   S +++ + N         ++I++ +F + VI SK  L Y E  + +    D  N   D+  +L  + K+A+ ++  R          L   + + S  +   +LQT+   E   ++EEFMLLAN  VA+ IY+++P+  LLR   +P  +  + L    +S N+       K   + L V   +             F  FN  ++       +C++Q                     + Y CS  DS +  H+ L   +YTHFTSPIRR+ D++VHRLL   I
Sbjct:  468 VCSVDPPGCTDIDDAL-HCRELENGNLEVGVHIADVSHFIRPGNALDKEAANRGTTVYLCGKRIDMVP-----ELLSSNLCSLRSNVERLAFSCIWEMNHN---------AEILKTQFTKSVINSKASLTYAEAQMRI----DDTNKKDDITESLRGLNKLAKILKRKRIENGALTLSSLEVRFHIDSETHDPIDLQTKELMETNSMVEEFMLLANISVAQKIYDEFPDCALLRKHPAPPPSNYDILLKAAKSMNVEIHTDSAKALADSLDVAKVDG------------FSYFNTLLR---ILATRCMMQ---------------------AVYFCSGMDS-DFHHYGLASPIYTHFTSPIRRYADIIVHRLLAVAI 788
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Medaka
Match: dis3l (DIS3 like exosome 3'-5' exoribonuclease [Source:NCBI gene;Acc:101159171])

HSP 1 Score: 102.834 bits (255), Expect = 2.319e-21
Identity = 118/466 (25.32%), Postives = 191/466 (40.99%), Query Frame = 2 
Query: 1424 EYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIR----EKHMILDKPHIT----LPSGAIVFTIDNKTTKDMDDAISYHREMNQIVI--GVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFS-DIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVD---ADLYMALESVYKIARKIRHARLPYSYF------VRSV----KNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVI 2749
            ++  VV    W    +YP G  V          +    ++ I   N + + P  E ++K +     EK   +D   +     L    +VF+ID    +D+DD +S        ++  GVHI+DVT +V P   +         T+Y   YL    Y +    L+ D  SL+ G  R  +SVL++     +  +   F   +++  ++    +++  LN EEV +   +   P   D   A L  ALE + +++R +R  R            VR+     KN  T L      E    + E M+ AN +VAR I E +PN  LLR   P +              L    QL +    +G   F+ ++R             N+ +  S  D+A  +   D   N   + +     +S   Y++   +      H+ L    YTHFTSPIRR+ D+VVHRLL + +
Sbjct:  382 DHRVVVRLDSWESTSLYPNGHSV---KVLGRAGELETEVQTILVENCIHVPPFSEAQMKEMPLSSPEKPWRVDPAEVARRRDLRDSHLVFSIDPLGCEDVDDTLSVRSLAGGTLLELGVHIADVTHFV-PEGSLTDLEARTRATTY---YLADRRYDMLPAVLSADLCSLLGGVDRYAMSVLWELDAGSLAVRRVWFGRTVIRSSYQLHYELAQALLNGEEVRVPELERFCPEEKDLKLAQLIQALEMLTRVSRHLRLQRDRGGALELEGVEVRAQLDKDKNI-TALVPRQPLEVHETVAECMIYANHWVARKIQESFPNRALLRRHPPPR--------------LELFSQLVDTAKAMG---FSVDTRT------------NKALADS-LDRA--VDPQDPMVNRL-LRMMATRAMSQALYFSTGSQPQDQYYHYGLALDRYTHFTSPIRRYADMVVHRLLTAAL 806
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Medaka
Match: dis3l (DIS3 like exosome 3'-5' exoribonuclease [Source:NCBI gene;Acc:101159171])

HSP 1 Score: 102.449 bits (254), Expect = 3.150e-21
Identity = 118/466 (25.32%), Postives = 191/466 (40.99%), Query Frame = 2 
Query: 1424 EYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIR----EKHMILDKPHIT----LPSGAIVFTIDNKTTKDMDDAISYHREMNQIVI--GVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFS-DIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVD---ADLYMALESVYKIARKIRHARLPYSYF------VRSV----KNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVI 2749
            ++  VV    W    +YP G  V          +    ++ I   N + + P  E ++K +     EK   +D   +     L    +VF+ID    +D+DD +S        ++  GVHI+DVT +V P   +         T+Y   YL    Y +    L+ D  SL+ G  R  +SVL++     +  +   F   +++  ++    +++  LN EEV +   +   P   D   A L  ALE + +++R +R  R            VR+     KN  T L      E    + E M+ AN +VAR I E +PN  LLR   P +              L    QL +    +G   F+ ++R             N+ +  S  D+A  +   D   N   + +     +S   Y++   +      H+ L    YTHFTSPIRR+ D+VVHRLL + +
Sbjct:  382 DHRVVVRLDSWESTSLYPNGHSV---KVLGRAGELETEVQTILVENCIHVPPFSEAQMKEMPLSSPEKPWRVDPAEVARRRDLRDSHLVFSIDPLGCEDVDDTLSVRSLAGGTLLELGVHIADVTHFV-PEGSLTDLEARTRATTY---YLADRRYDMLPAVLSADLCSLLGGVDRYAMSVLWELDAGSLAVRRVWFGRTVIRSSYQLHYELAQALLNGEEVRVPELERFCPEEKDLKLAQLIQALEMLTRVSRHLRLQRDRGGALELEGVEVRAQLDKDKNI-TALVPRQPLEVHETVAECMIYANHWVARKIQESFPNRALLRRHPPPR--------------LELFSQLVDTAKAMG---FSVDTRT------------NKALADS-LDRA--VDPQDPMVNRL-LRMMATRAMSQALYFSTGSQPQDQYYHYGLALDRYTHFTSPIRRYADMVVHRLLTAAL 806
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Planmine SMEST
Match: SMESG000026061.1 (SMESG000026061.1)

HSP 1 Score: 3038.05 bits (7875), Expect = 0.000e+0
Identity = 1508/1516 (99.47%), Postives = 1510/1516 (99.60%), Query Frame = 2 
Query:  836 MKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVV 5383
            MKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTLSSQDSLQDSLPLIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFK SDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFVSYNYSNIISSDSFSFVEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFN+YEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILG ETNKKINNPTEKIIAQI+NELNWKKFNRNQ NAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIV NKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADK GLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYK FLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVV
Sbjct:    1 MKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTLSSQDSLQDSLPLIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKLSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFVSYNYSNIISSDSFSFVEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNKYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGTETNKKINNPTEKIIAQIDNELNWKKFNRNQNNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVNNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKHGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKVFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVV 1516
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Planmine SMEST
Match: SMESG000026061.1 (SMESG000026061.1)

HSP 1 Score: 3036.51 bits (7871), Expect = 0.000e+0
Identity = 1508/1516 (99.47%), Postives = 1510/1516 (99.60%), Query Frame = 2 
Query:  836 MKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVV 5383
            MKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTLSSQDSLQDSLPLIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFK SDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFVSYNYSNIISSDSFSFVEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFN+YEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILG ETNKKINNPTEKIIAQI+NELNWKKFNRNQ NAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIV NKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADK GLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYK FLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVV
Sbjct:    1 MKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTLSSQDSLQDSLPLIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKLSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFVSYNYSNIISSDSFSFVEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNKYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGTETNKKINNPTEKIIAQIDNELNWKKFNRNQNNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVNNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKHGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKVFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVV 1516
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Planmine SMEST
Match: SMESG000026061.1 (SMESG000026061.1)

HSP 1 Score: 3034.2 bits (7865), Expect = 0.000e+0
Identity = 1504/1512 (99.47%), Postives = 1506/1512 (99.60%), Query Frame = 2 
Query:  836 MKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVE 5371
            MKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTLSSQDSLQDSLPLIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFK SDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFVSYNYSNIISSDSFSFVEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFN+YEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILG ETNKKINNPTEKIIAQI+NELNWKKFNRNQ NAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIV NKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADK GLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYK FLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVE
Sbjct:    1 MKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTLSSQDSLQDSLPLIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKLSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFVSYNYSNIISSDSFSFVEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNKYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGTETNKKINNPTEKIIAQIDNELNWKKFNRNQNNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVNNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKHGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKVFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVE 1512
[Close]
BLAST of Helicase with zinc finger domain 2 vs. Planmine SMEST
Match: SMESG000026073.1 (SMESG000026073.1)

HSP 1 Score: 1944.47 bits (5036), Expect = 0.000e+0
Identity = 1020/1870 (54.55%), Postives = 1341/1870 (71.71%), Query Frame = 2 
Query:  260 NISIWMSYIIDDDIEYLVNERLKSLKKVAIGRIDCLWSCLYNYLTKSNTKTDEYKDFHQLKSAFYLKCESLKKEKEDLDHVAMKYFANQYKMQLRFSSIDESLKEIIYGRNLLKSVHFLHIGLDLFLPLELNECKDHYKFSNEEKTKLGELTNINEKKIEDKLKFXXXXXXXXXXXXXXXXXTRADSY--DFESMKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYK--NKIKNENKTISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENV-NFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAE--TNKKINNPTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFK-NKTLPIDIQEVSLHFLIRKNG-GYADELKKFDNIFKCIRNKD---PIPPDFN--VYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSILL-KKTTTSPIVKTVIRSQGSENDYVIFSTVRSM-NIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            +IS+WM  I+DD+ E  + E++KSLKKV  G+I  LW CL+  L K        K+ ++L+   Y   +  K   E+ +  A+      YK Q+R SS D + KEIIYG NL + +H LHIG+  FLPL+     + + FS EE   + +L  +N     D+     E K L ++ K+L G+ + ++Y        R+ L Y++YTP+QL +  D LI C LK   + SG AIP++  A+ K+KEI L SR NCG+N F NDIVYVKI + K H+GKVMGVY+S HKPVN +Y+CKVS+DQG+LM PLDKSFPKIHV+N  GR  Y+  +  + + K I  EQ+S  D E+  + +ADN Y+S+F I  +N+ ++ PI+     + F+P+TC++ F+V Y+ W+P+FMYP G+IVGT+SS DS +++ PLI  IC +N L+I+P+Y+KEV  I++K + +  P   LP+ ++VFTID++TTKDMDDA+S+H+E + I+IGVHI+DVTKY+SPT E+YKQA+  FCT YPPK+ NI P H+ D+ LATD LSL P KPRAVVSVLF+F   M+ + +FK S+I+QP FR+ VIIS++KL YEEVS WLKQ +   N   +L  AL  ++ +A+KIR ARLP SYFV SV +CY ++  E  FEA ++IEEFMLLANEYVAR IYEKYP+ TLLRMQ PVKN  EWLENL   TN+NFAGQLKE+CNLL V   N ++R+K IVS+ F+E FN F+   D DKA+ LLQYD Y+N+F+VHI +WY ++ P+ Y CS KDS+   HFSLNK LYTHFTSPIRRFTD+VVHRLLKSV++  +IDD +LDI E+C  AN K   NKNFEK+C P+AI +ET+K+FC ILDC CS+I +EEI   HP+LQ ASS   IKFA+LSL+ VP+  K++E    C LKW+KII+SC PY  S+S+  N F +D+  FD +LP+S  KLFQEIRRSYL    L++KL+QL + FV+  +  +ISSDS S   PI+DIEL + +KNTMRIQFCKYK +GL  I PEL +V+P+F ICLIH+++P  FFI GGKL L HN +K+ F+ IKEY+DYF PL+  ESL E L + SAFTL  V I+W++G+S+ TK+ ERYGV+ L  DFC  R+ IF+ E     +RYE L+  G SSVGGDLLCLR +K++WNNYW+GHG VV + K  + + + K++IF LTQS+FD+  +  N+ N+++D+Y KS+VS RQQ  ++ ID   LLKEVILG    +    NN    I   IEN   + KFN+NQ  A+ NA+N KLSLIWGPPGTGKT +GC LS+A+   N +     VVLYCGPSNDC+NLVA  M +KF++ CPKLLRI+G++QE++DFP+PG F K N  L  ++Q++SLH+LIR+ G  +AD L   D  F+ I   D    +  +    ++N+IL+Y++ VK+AKK  I+KN+++M+LCTT+VT   ++  FNI Q+IIDEAGMCKEPETLIP+++A  +V+NVVLIGDHKQLRP+I +++A K GL+ISLFERYQ+LKP+LVTMLN QYRMHPSIC+FPS EFY  +L T VSPLW GL  D M+   +S             WNGI+Y     HY+  L+ SNY+A+PD KWP  R  P++CF+K F  YPERI+F  VIG+E+ Q VTT TGNE S+GN  EVE VG IYKK++E   PPR +PNFITVLTQY  QQHLLEM+CK IL  KK  T PIVKTVIRSQGS+NDY+IFSTVRS+ N EDIN +PT GWE+++LGFIT+ NQINVALTRA+KGLIIIGNK+LL+VN  WK+LI++LEERNCV  DYLN
Sbjct:  104 DISLWMKCIVDDNNENSIMEKMKSLKKVPNGKISELWDCLFKQL-KILYDNLPLKESYELRKFIY---QMDKDSNENRNENALTNMCQYYKCQVRVSSFDNNFKEIIYGSNLQRCIHLLHIGMQYFLPLQSGILTNTFTFSKEETKLISDLKQLNANSTVDQYAVDQERKRLNDIRKMLMGMEKQETYVPMVNPNSRKKLLYEIYTPEQLSKRTD-LIKCILKFTNAHSGRAIPVDRSADMKYKEIKLISRHNCGYNAFQNDIVYVKINDPKNHTGKVMGVYESNHKPVNSIYICKVSRDQGSLMSPLDKSFPKIHVDNEPGRRRYEVNDMERKKTKNIQNEQKSVADLEQELSRFADNLYYSVFKIK-VNKNSDKPIYFPKDVVPFNPETCDHFFIVCYEYWDPYFMYPNGKIVGTISSYDSFKNNFPLISLICQINPLDITPRYQKEVDEIKKKAVCVHVPGSYLPTDSVVFTIDSETTKDMDDALSFHKEGSDIIIGVHITDVTKYISPTHEIYKQAESRFCTYYPPKFSNIHPIHLLDDTLATDVLSLAPNKPRAVVSVLFRFPGRMLINPDFKLSEIIQPTFRQGVIISQFKLTYEEVSSWLKQPNQIPNDKENLIYALNEIFAVAKKIRRARLPESYFVCSVNDCYKDMDIETIFEARIVIEEFMLLANEYVARKIYEKYPDFTLLRMQDPVKNCGEWLENLFNLTNMNFAGQLKEFCNLLNVRPDNFDARKKLIVSKNFYEQFNNFL-SIDIDKARSLLQYDAYYNDFFVHIREWYQMNYPARYECSVKDSIENKHFSLNKPLYTHFTSPIRRFTDIVVHRLLKSVLNGTEIDDITLDIGEVCTIANKKLNGNKNFEKICAPFAIFDETDKKFCFILDCACSDITNEEIRFVHPMLQKASSIKEIKFADLSLNAVPLSLKNDEKAESCLLKWKKIIYSCNPYFKSTSNRRN-FVVDNSQFDCHLPFSSYKLFQEIRRSYLPAVKLKDKLHQLKSSFVNQTFDTVISSDSISLANPIIDIELKIFIKNTMRIQFCKYKVNGLPAIKPELHIVSPTFQICLIHRDDPVPFFIPGGKLKLNHNTIKKVFTDIKEYQDYFSPLVHVESLQETLGEPSAFTLIDVTIEWLVGESLITKRKERYGVMKLPDDFCKSRNIIFNDERDSNGSRYEVLLERGFSSVGGDLLCLRLKKDNWNNYWIGHGEVVHVAKPKLESGEFKIVIFMLTQSDFDIFSNNSNIQNYSVDVYLKSVVSKRQQEAISSIDTHPLLKEVILGINELSPDDENNFINSIKNDIENRRIF-KFNQNQSQAMSNAMNHKLSLIWGPPGTGKTHIGCILSYAFAQKNYRIRNKGVVLYCGPSNDCVNLVALEMKKKFSDLCPKLLRIYGEQQELADFPLPGFFSKTNVPLTGELQQISLHYLIRQQGESHADILSSHDRYFQKILTTDRNYSLSENIREAIHNSILSYRDAVKEAKKNLIIKNQYEMVLCTTTVTATTIMELFNITQIIIDEAGMCKEPETLIPMSSAENTVENVVLIGDHKQLRPIIHNKVAKKLGLEISLFERYQELKPKLVTMLNYQYRMHPSICEFPSKEFYFHQLKTQVSPLWSGLGPDDMEKCSYSQ------------WNGINYRLCKLHYESILRQSNYSAVPDDKWPAFRHIPYKCFNKGFIRYPERIVFYHVIGDEVIQPVTTQTGNENSRGNPQEVEAVGCIYKKIIENLTPPRQSPNFITVLTQYKLQQHLLEMKCKDILQKKKIKTDPIVKTVIRSQGSQNDYIIFSTVRSIRNREDINQHPTIGWEKQYLGFITDPNQINVALTRAQKGLIIIGNKQLLRVNHIWKRLIQDLEERNCVKEDYLN 1952
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BLAST of Helicase with zinc finger domain 2 vs. Planmine SMEST
Match: SMESG000026051.1 (SMESG000026051.1)

HSP 1 Score: 1691.78 bits (4380), Expect = 0.000e+0
Identity = 937/1877 (49.92%), Postives = 1276/1877 (67.98%), Query Frame = 2 
Query:  239 KKIYKDGNISIWMSYIIDDDIEYLVNERLKSLKKVAIGRIDCLWSCLYNYLTKSNTKTDEYKDFHQLKSAFYLKCESLKKEK--EDLDHVAMKYFANQYKMQLRFSSIDESLKEIIYGRNLLKSVHFLHIGLDLFLPLELNECKDHYKFSNEEKTKLGELTNINEKKIEDKLKFXXXXXXXXXXXXXXXXXTRADSYDFESMKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLANKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPVNKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKT-ISTEQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDTCEYLFVVLYQKWNPHFMYPYGRIVGTXXXXXXXXXXXXXIRAICNLNLLEISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYHREMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIFDEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDVIISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPYSYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTLLRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFIVSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYYNCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDDCSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEINDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRKIIFSCPPY-LNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEALENKLNQLCTKFXXXXXXXXXXXXXXXXXEPIVDIELDMCVKNTMRIQFCKYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKESFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKKTERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCLRCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAENVN-FTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINN------PTEKIIAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFAYTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQEVSDFPIPGHFFKN-KTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCIRNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQVVTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIRSRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGKLITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYIN-WNGID-YEKSVDHYKEFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQSVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSYQQHLLEMECKSIL-LKKTTTSPIVKTVIRSQGSENDYVIFSTVRSM-NIEDINYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKKLIENLEERNCVIADYLN 5821
            KKI K GNIS WM YIID +I  L+ E+L SL +   G I  LW CL+  L +    T+ + +   LK   Y   ESL      E+ +H A++ F+ +YK++++F+SID++  EIIY               DLFLPLE +  +  YK + E++ K+ ++    +KK+   LK   +   LK L KLLKGL    S    +  +  L+YD YTP +L++M D LILC+LKI  + SG+AIPI+   + K++EI L +R+NCG+N F  DIV VKI + K  +GKV+ VY+S+HKP+N +YVCKV++DQG+LM PLD +FPKIHV+N  G   Y+++I+   K+ +  EQ+S +++ K    YADN Y+SLFD++ +N+  N   F      +F P TC+  F+V Y++W+P +MYPYG++VG L+ +D+L+++  LI +ICN+  + ++ +YEKEV+ I  K  +L++    +PS A+VFTID+K TKD+DDAISYH+E N  VIG+HISDVTKY+S T E+Y QA+  FCT YPP      P H+ DE+L+TD LSL+P  PRAVVSV F+F  N+  D  FK +D+   +FRE VI+SK+KL YEEVS WLKQ+  P NVD +L+ AL++ ++I++ +R ARLP SYFVRS      +L  +N+FEAE L+ EFMLLANE VA+ +Y KYP+STLLR+Q+ V+N E WL++L +STN+NF G+L +YC+LL V N +   ++  +VSRKFFE F   IK+ D D AK LL YD Y+NEF VHI DWY I+ P+ Y CS K+SVN  HFSLNK LYT+FTSPIRRF+D+VVHRLLKSVI+   IDD SLDI  +C  AN K K N  FE++C  Y + E+ NK FC ILDC CSEIN++ I+ AH LLQ + S   +KF+ L+L ++P   +  E    C LKWR+II+SC    + +++ +   F ID  L++  L    SK F  IRRS   G+ L+ KL    +KF+   Y+ +ISSD +S   PI+DI+L + VK+TMRIQF K K  GL +I PEL++VTP+F ICLIHQ++P +FF+  GKL L +N  K  F++I EYK+YFEPLI  ESL E LS   +FTL  V IKWIL       K  RYGVI L   FC  ++  F  E   I NRYE+LI   +S +G DLLCLR +   WNNYW+GHG VV  +K    N   K+IIF LT S+FD   + ++ N +++D+Y KS+V+ RQQ++M  +++ EL+ ++I+G + +  I+N       TEK+ +          FN++Q  A+  AL  K SLIWGPPGTGKT +GC LSF YT   R  +  +VVLYCGPSNDC++LVA+ + ++FNE CPKLLRI+ K+QE++DFP+PG+F +N + L  +++  SLHFLIRK G + D L+  D  F+ I       P+  +++ I  YK L+ KAK++Y+ K K+D++LCTTSVT  +++  FNI QVI+DEAGMCKEPETLIPI+    S+KN+VLIGDHKQLRP+I SRLA+  GLQISLFERYQ L   +VT+LN QYRMHPSIC+FPS EFYS KL T  S LW GL ++ ++V          +++ Y N WNG+D +  +   + E  + SNY  I D KWP +  +P+ CF ++F  YPER IFID+IG E++QSVTT+TGNE SKGNK EVEV GYIY++L+E+    R     I++LTQY  QQHLL++ C+ IL  KK  + PIVKTVIRSQGSENDY+IFSTVRS+ N  DIN +PT GWE+++LGFIT+ +QINVALTRAKKGLII+GN++LL+VN+TWKK+I N  ERNC++ +YLN
Sbjct:   46 KKISKIGNISTWMCYIIDGNIVNLIKEKLSSLNENVCGDILNLWDCLFYQLNRIIDITNGFDNPLLLKQYVY---ESLCGGSCLENQNHEALEAFSEEYKIKVKFTSIDKNSTEIIY---------------DLFLPLEASGSRKEYKPNLEDQRKI-KMAIQCDKKVNSNLKSVQDNNRLKELRKLLKGLETVQSPVPINKLQAKLEYDTYTPDELEKMDD-LILCELKIIGAHSGIAIPIKT-QSVKYEEIKLLNRRNCGYNAFDGDIVRVKINDPKIPTGKVVDVYESYHKPINSIYVCKVNRDQGSLMTPLDSTFPKIHVDNQHGHRQYESEIQKREKSFLKDEQKSVVERGKESFKYADNLYYSLFDVS-VNE--NKLHFQFKSVEKFDPHTCDNYFIVCYERWDPQYMYPYGKVVGILNGRDTLEENFELISSICNIESVNLTAQYEKEVQEIIGKVKLLNESEDYIPSDAVVFTIDSKNTKDIDDAISYHKEGNDTVIGIHISDVTKYISSTHEIYYQAQRRFCTIYPPYK---KPIHLIDERLSTDALSLIPNVPRAVVSVFFRFPSNVTTD--FKITDL---KFREGVIVSKHKLTYEEVSKWLKQNQVPENVDPNLFEALKNSFEISKNLRQARLPKSYFVRSTNKFVKDLYVDNQFEAETLVNEFMLLANENVAKKVYYKYPDSTLLRIQNSVRNYENWLDSLLQSTNMNFEGELNDYCSLLEVKNADFPVKKNILVSRKFFERFISLIKK-DADSAKNLLLYDIYYNEFMVHIIDWYKINCPARYECSYKNSVNNKHFSLNKDLYTNFTSPIRRFSDIVVHRLLKSVINGKMIDDSSLDIHYVCSIANQKYKSNDRFEEICASYTVFED-NKTFCFILDCTCSEINEDGIVVAHHLLQKSLSLKTMKFSYLTLSDLPFFKE--EKTDNCTLKWRRIIYSCSTSNIENNTDSTGTFVIDKDLYNVSLSSEASKEFGAIRRSCTHGQTLKEKLQNFKSKFIVSKYNTLISSDLYSIFNPIIDIQLQVFVKSTMRIQFSKNKVHGLPKITPELYIVTPTFQICLIHQDDPVRFFVQDGKLKLKYNINKTRFTTIAEYKEYFEPLIHAESLEETLSGDISFTLLSVQIKWILKVYSPNGKKVRYGVIMLPEKFCQEKNIHFSDEKSDIINRYEHLIDEELSPIGSDLLCLRFKCASWNNYWIGHGEVVHASKFQQENTIYKIIIFLLTHSDFDAFSTIQDKNTYSVDVYNKSVVTRRQQLLMKSLEENELVCDIIMGKDLS--IDNIDCGTLVTEKMFS----------FNKSQKQAMIRALKHKFSLIWGPPGTGKTFIGCCLSFEYT--QRNLSTENVVLYCGPSNDCVDLVANYLRKQFNESCPKLLRIYSKQQELTDFPVPGYFVRNCQPLSDEMKPFSLHFLIRKEGNFVDLLRVCDEKFRSILQSKKCNPEERLHDLIQNYKGLLLKAKRDYVSKVKYDIVLCTTSVTATKIMKSFNITQVIVDEAGMCKEPETLIPISKMENSIKNIVLIGDHKQLRPIILSRLAESHGLQISLFERYQNLPNGVVTLLNFQYRMHPSICEFPSKEFYSSKLKTQASILWSGLTANDLRV----------EQDYYDNEWNGLDSFNLAGFEFDELRRKSNYLVIKDEKWPRRDDKPYNCFDRKFSWYPERTIFIDIIGTEVAQSVTTSTGNENSKGNKTEVEVCGYIYRRLIESGAQAR----SISILTQYKLQQHLLKLNCQDILKSKKIMSDPIVKTVIRSQGSENDYIIFSTVRSLTNKNDINTHPTQGWERQYLGFITDPHQINVALTRAKKGLIIVGNRQLLQVNETWKKIINNYSERNCIVNNYLN 1858
The following BLAST results are available for this feature:
BLAST of Helicase with zinc finger domain 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HELZ24.827e-9524.24helicase with zinc finger 2 [Source:HGNC Symbol;Ac... [more]
HELZ25.519e-9524.24helicase with zinc finger 2 [Source:HGNC Symbol;Ac... [more]
UPF11.406e-4225.55UPF1 RNA helicase and ATPase [Source:HGNC Symbol;A... [more]
UPF12.358e-4125.16UPF1 RNA helicase and ATPase [Source:HGNC Symbol;A... [more]
DIS3L4.281e-2526.26DIS3 like exosome 3'-5' exoribonuclease [Source:HG... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
smg-21.059e-3727.79Regulator of nonsense transcripts 1 [Source:UniPr... [more]
smg-21.059e-3727.79Regulator of nonsense transcripts 1 [Source:UniPr... [more]
smg-21.059e-3727.79Regulator of nonsense transcripts 1 [Source:UniPr... [more]
disl-23.482e-2127.12DIS3-like exonuclease 2 [Source:UniProtKB/Swiss-P... [more]
dis-33.767e-2025.37Probable exosome complex exonuclease RRP44 [Sourc... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Upf13.869e-2728.88gene:FBgn0030354 transcript:FBtr0342744[more]
Upf13.869e-2728.88gene:FBgn0030354 transcript:FBtr0073596[more]
CG75047.661e-2229.67gene:FBgn0035842 transcript:FBtr0273368[more]
Dis3l29.213e-2227.72gene:FBgn0035111 transcript:FBtr0072487[more]
Dis3l29.456e-2227.72gene:FBgn0035111 transcript:FBtr0072486[more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-97a13.63.138e-10225.64si:dkey-97a13.6 [Source:ZFIN;Acc:ZDB-GENE-070912-6... [more]
helz28.762e-8224.95helicase with zinc finger 2, transcriptional coact... [more]
zgc:1130572.514e-5228.90zgc:113057 [Source:ZFIN;Acc:ZDB-GENE-050508-3][more]
upf11.351e-4026.03UPF1 RNA helicase and ATPase [Source:ZFIN;Acc:ZDB-... [more]
upf11.351e-4026.03UPF1 RNA helicase and ATPase [Source:ZFIN;Acc:ZDB-... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tbx216.513e-4723.62T-box 21 [Source:Xenbase;Acc:XB-GENE-479103][more]
UPF14.123e-4125.16UPF1 regulator of nonsense transcripts homolog [So... [more]
UPF14.193e-4125.16UPF1 regulator of nonsense transcripts homolog [So... [more]
UPF14.409e-4125.16UPF1 regulator of nonsense transcripts homolog [So... [more]
UPF14.818e-4125.16UPF1 regulator of nonsense transcripts homolog [So... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Helz21.995e-5237.14helicase with zinc finger 2, transcriptional coact... [more]
Helz22.002e-5237.14helicase with zinc finger 2, transcriptional coact... [more]
Helz28.047e-4536.55helicase with zinc finger 2, transcriptional coact... [more]
Upf14.457e-4325.42UPF1 regulator of nonsense transcripts homolog (ye... [more]
Upf11.616e-4125.03UPF1 regulator of nonsense transcripts homolog (ye... [more]
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BLAST of Helicase with zinc finger domain 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9BYK8|HELZ2_HUMAN2.650e-9424.24Helicase with zinc finger domain 2 OS=Homo sapiens... [more]
sp|E9QAM5|HELZ2_MOUSE1.396e-5137.14Helicase with zinc finger domain 2 OS=Mus musculus... [more]
sp|Q9EPU0|RENT1_MOUSE3.117e-4225.42Regulator of nonsense transcripts 1 OS=Mus musculu... [more]
sp|Q92900|RENT1_HUMAN6.750e-4225.55Regulator of nonsense transcripts 1 OS=Homo sapien... [more]
sp|P30771|NAM7_YEAST8.142e-4129.40ATP-dependent helicase NAM7 OS=Saccharomyces cerev... [more]
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BLAST of Helicase with zinc finger domain 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210QEW81.910e-13727.31Helicase with zinc finger domain 2 OS=Mizuhopecten... [more]
A0A2R2MRF97.670e-13327.05helicase with zinc finger domain 2 OS=Lingula ungu... [more]
C3XYY12.001e-12925.46Uncharacterized protein OS=Branchiostoma floridae ... [more]
A0A1S3IYB32.969e-12726.84helicase with zinc finger domain 2 OS=Lingula ungu... [more]
A0A2R2MN277.023e-11928.01helicase with zinc finger domain 2-like OS=Lingula... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
helz21.043e-7924.66helicase with zinc finger domain 2-like [Source:NC... [more]
upf11.336e-4026.03UPF1 RNA helicase and ATPase [Source:NCBI gene;Acc... [more]
ENSAMXT00000036328.11.826e-3138.73pep primary_assembly:Astyanax_mexicanus-2.0:5:1303... [more]
mov10a2.269e-2525.96putative helicase mov-10-B.1 [Source:NCBI gene;Acc... [more]
mov10b.15.607e-2325.96Moloney leukemia virus 10b, tandem duplicate 1 [So... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008666.16.989e-5137.17pep scaffold:Pmarinus_7.0:GL478401:184246:194592:-... [more]
ENSPMAT00000008661.16.550e-3637.61pep scaffold:Pmarinus_7.0:GL478401:184160:191851:-... [more]
upf12.160e-2828.54UPF1 RNA helicase and ATPase [Source:ZFIN;Acc:ZDB-... [more]
dis3l2.172e-2123.31DIS3 like exosome 3'-5' exoribonuclease [Source:NC... [more]
ighmbp22.329e-1926.07immunoglobulin mu DNA binding protein 2 [Source:ZF... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
NAM71.173e-4229.40ATP-dependent RNA helicase of the SFI superfamily;... [more]
HCS17.152e-2726.84Hexameric DNA polymerase alpha-associated DNA heli... [more]
DIS33.366e-2426.62Exosome core complex catalytic subunit; has both e... [more]
ECM321.026e-1828.79DNA dependent ATPase/DNA helicase; helicase belong... [more]
SEN15.282e-1727.07ATP-dependent 5' to 3' RNA/DNA and DNA helicase; s... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO451373.004e-6523.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO310255.765e-5335.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO310243.202e-2748.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO424291.468e-2527.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO344965.275e-2424.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000013379.22.362e-8325.88helicase with zinc finger 2 [Source:NCBI gene;Acc:... [more]
UPF11.734e-4025.16UPF1 RNA helicase and ATPase [Source:NCBI gene;Acc... [more]
dis35.826e-2527.06DIS3 homolog, exosome endoribonuclease and 3'-5' e... [more]
dis3l2.319e-2125.32DIS3 like exosome 3'-5' exoribonuclease [Source:NC... [more]
dis3l3.150e-2125.32DIS3 like exosome 3'-5' exoribonuclease [Source:NC... [more]
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BLAST of Helicase with zinc finger domain 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000026061.10.000e+099.47SMESG000026061.1[more]
SMESG000026061.10.000e+099.47SMESG000026061.1[more]
SMESG000026061.10.000e+099.47SMESG000026061.1[more]
SMESG000026073.10.000e+054.55SMESG000026073.1[more]
SMESG000026051.10.000e+049.92SMESG000026051.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006144 ID=SMED30006144|Name=Helicase with zinc finger domain 2|organism=Schmidtea mediterranea sexual|type=transcript|length=5959bp
TCGTTAAGGTCAGCGTTCCATCCTTAAACAAAGATTTGACTAAGTTTTCA
TTTCATTATTTTTTAATTTAATGAATGAAAATGAAGATAATAATCGGATA
AAAGTTAAAGGAAAACAAGAAACATGTAAATTTTCATCTCCCGAAAGAGA
TAGTCAAAATGATTATTACATTCAACCCGAAAGTACAAATCAAGAGTATT
CCGACTTCTTTGTTGTATCTATACATGCTGATTTAGAAAAAAAGATTTAT
AAAGACGGAAATATATCAATTTGGATGTCTTATATTATTGATGATGATAT
TGAATATCTTGTTAATGAAAGGCTAAAATCGCTTAAAAAAGTTGCTATCG
GAAGAATCGATTGTTTATGGAGCTGTTTATATAATTATCTAACCAAATCT
AATACTAAAACTGATGAATATAAAGATTTTCATCAACTAAAAAGTGCATT
TTATCTGAAGTGTGAAAGTCTAAAGAAAGAAAAGGAGGATTTGGATCATG
TTGCAATGAAATATTTTGCGAATCAATACAAAATGCAGTTGAGATTTTCT
TCGATCGATGAAAGCTTAAAAGAAATAATTTATGGCAGAAATTTGTTAAA
ATCAGTCCATTTCTTGCACATTGGACTAGATTTATTCTTACCATTGGAGT
TAAATGAATGTAAAGATCATTATAAATTTTCAAACGAAGAGAAAACTAAA
TTAGGAGAACTGACAAATATAAATGAAAAAAAAATTGAAGACAAATTAAA
ATTTAAGAATGAAGTGAAAACATTGAAAAATCTAAACAAATTATTGAAAG
GGTTAACACGAGCAGATTCTTATGACTTTGAAAGTATGAAGAGGCGAGGA
CTTCAATATGACGTTTATACTCCTAAACAATTAGATGAAATGAAAGATAA
ATTAATACTGTGTAAACTGAAAATCAATAAATCTCAATCTGGATTGGCTA
TTCCTATTGAGAATCTAGCCAATAAGAAATTTAAAGAAATCATCCTTACA
AGCCGTCAAAATTGCGGTTTCAACGTGTTCTTAAACGATATTGTTTATGT
CAAAATTATAAATGAGAAATTTCATAGTGGAAAGGTAATGGGTGTCTATC
AATCTTTCCACAAACCAGTGAATAAATTATATGTTTGTAAAGTATCAAAG
GACCAAGGAAATTTGATGGTCCCATTGGATAAATCATTTCCAAAAATACA
CGTAGAAAATACAGCTGGCAGAAATCTTTATAAAAATAAAATAAAAAATG
AAAATAAAACCATATCAACAGAACAAGAATCGTTTTTAGATAAAGAAAAG
AATCGTAATTCATATGCTGATAATACATACTTTTCACTCTTTGATATTAC
TGGAATAAACCAGTTGACGAATATGCCAATTTTTGGAAATTGCAGATGCA
TAGAATTTAGTCCTGATACTTGTGAATATTTATTTGTCGTCTTATATCAG
AAATGGAATCCTCATTTTATGTATCCTTATGGTAGAATTGTTGGAACTTT
GTCAAGTCAAGATTCATTACAAGATAGTTTGCCTCTAATTAGAGCGATTT
GTAACCTAAATTTATTAGAGATCTCACCAAAATATGAAAAAGAAGTAAAA
ACAATTCGAGAAAAACACATGATTTTGGACAAACCCCATATAACTCTTCC
TTCAGGAGCCATTGTATTTACAATTGACAATAAAACGACAAAAGATATGG
ATGACGCAATCAGCTATCATCGGGAAATGAATCAGATTGTAATTGGAGTT
CACATATCCGATGTTACAAAATACGTTTCTCCAACCTCTGAAATGTATAA
ACAAGCTAAAGATTGTTTTTGTACCTCGTATCCACCAAAATATTTAAACA
TCCCTCCGTATCATATATTTGATGAGAAATTAGCTACTGATTTTCTTAGC
TTAGTTCCTGGTAAACCTCGAGCTGTTGTTAGTGTGTTGTTTAAATTCTC
TGAAAATATGATTAATGATAAAAATTTCAAATTTTCTGATATTGTTCAAC
CTGAATTTCGTGAGGATGTAATAATATCAAAATACAAATTAAACTATGAA
GAAGTATCTTTGTGGCTCAAACAATCTGATGATCCAGCAAACGTGGATGC
TGATCTATACATGGCTCTTGAAAGTGTTTATAAAATAGCGCGAAAAATCC
GTCATGCGCGGCTACCGTACTCATATTTTGTTCGATCAGTTAAAAACTGT
TATACAAATTTACAGACAGAAAATAGATTTGAAGCTGAATTACTAATCGA
AGAATTTATGTTATTGGCAAACGAATATGTCGCTAGAATAATCTACGAGA
AATATCCGAATTCCACACTGTTGAGAATGCAAAGTCCAGTTAAAAATCGA
GAGGAATGGTTAGAAAATTTACATGAATCTACAAACTTGAATTTTGCCGG
ACAGCTGAAAGAATACTGCAATTTGCTGGGGGTATTAAATTTTAATCGTA
ACTCTAGACAAAAGTTTATTGTTAGTAGGAAGTTTTTTGAGTTATTTAAC
GAATTTATCAAACAGTCCGATTTTGATAAGGCTAAATGTCTTTTGCAGTA
CGATGAATATTTTAACGAGTTTTATGTTCATATAACGGATTGGTATCATA
TTTCTAATCCGTCGTACTATAATTGCAGCGAAAAAGATAGTGTTAATATG
GGACATTTTTCATTGAATAAATCATTATATACTCATTTCACAAGTCCTAT
TCGAAGATTTACTGATGTAGTAGTTCATAGACTTCTGAAATCTGTCATTC
ATAAAATTGATATTGATGATTGTTCACTCGATATTGATGAAATATGTGTA
AATGCAAATACAAAAAGTAAATATAATAAAAACTTTGAAAAGTTATGTGA
GCCGTATGCGATTGTTGAAGAAACAAATAAACGATTCTGTCTGATTCTGG
ATTGTGTTTGCAGTGAGATTAACGACGAAGAAATTATTTGTGCACATCCA
CTATTACAAGTGGCATCAAGCGATAATAGAATTAAATTTGCCAATTTGTC
TCTAGATGAGGTGCCAGTTCTGTCGAAAAGTAATGAAAATTTTGGAAAAT
GTAATTTAAAATGGAGGAAAATAATATTTTCTTGTCCTCCTTATCTAAAC
AGTTCTAGTTCAAATGATAACAAATTTAAGATTGACAGTCATTTATTCGA
CTCCTATTTGCCTTATTCTGACTCGAAATTGTTTCAAGAAATTAGACGGT
CTTATCTTTCTGGAGAAGCCTTAGAGAATAAATTGAATCAACTGTGCACA
AAATTTGTCTCATATAATTATTCGAATATCATTTCATCAGACTCGTTTTC
TTTTGTTGAACCTATTGTCGACATCGAATTGGACATGTGCGTTAAAAATA
CGATGAGAATACAATTTTGCAAATATAAAGCAAGTGGTTTGATGCAAATT
AATCCGGAATTGTTTGTTGTCACACCAAGCTTTCATATTTGTTTAATCCA
TCAAAATAATCCTTCTAAATTCTTCATATCAGGTGGCAAGCTGGATTTAC
TGCACAATAATGTAAAGGAATCATTTAGTTCAATCAAAGAATATAAGGAT
TATTTTGAACCTTTAATTGAAGATGAGTCTTTAATGGAAGCGTTAAGTGA
CCGCAGTGCTTTTACTCTCGAGAAAGTTTTAATAAAGTGGATTTTGGGTA
AGTCAATTAAAACAAAAAAAACAGAAAGATATGGAGTTATTACACTGTCA
TCTGATTTCTGTAATTTGAGGAGTGACATTTTCCATAAAGAAATCTATAA
AATATTTAACAGGTATGAATATTTAATTGCTTCAGGCATATCTTCCGTCG
GAGGTGATCTGTTGTGTTTGAGATGTAGGAAGGAAGATTGGAATAATTAT
TGGGTTGGTCATGGCCATGTTGTAACCATAAATAAATGCATGATTAATAA
TCAAAAAATGAAATTAATAATATTTCGACTAACTCAATCAAATTTTGATC
TGCCTAAATCTGCAGAAAATGTAAATTTTACTCTGGATATCTATCAGAAA
TCTATCGTATCAATTCGTCAGCAAGTTATTATGAATAAGATTGACAAAAT
TGAATTGCTTAAAGAAGTTATACTTGGAGCTGAAACAAATAAAAAAATAA
ATAATCCAACAGAGAAAATAATCGCGCAGATAGAAAACGAATTGAATTGG
AAAAAATTTAATAGAAACCAGTATAATGCTGTCAAAAATGCTTTGAATCA
AAAACTAAGTTTAATTTGGGGTCCTCCAGGCACTGGTAAAACTATGGTTG
GATGTTATTTGTCGTTTGCATACACGTTTGTTAACAGAAAAGAAAATAAA
AATTCAGTTGTTCTTTATTGTGGACCGTCAAATGATTGTATCAACCTCGT
TGCTAGTACAATGATGGAAAAATTTAACGAAAAGTGTCCCAAATTGTTGA
GAATATTTGGCAAGGAACAAGAAGTATCAGATTTTCCTATACCTGGACAT
TTTTTCAAAAATAAAACTCTGCCTATAGATATTCAGGAAGTTAGCTTACA
TTTCTTAATTCGAAAAAATGGAGGATATGCTGATGAGTTGAAAAAATTCG
ATAACATATTTAAATGTATTCGTAATAAAGACCCAATACCTCCTGATTTT
AACGTTTACAACGCAATCTTAACGTATAAGAATTTAGTGAAAAAAGCAAA
GAAGGAATATATTGTTAAAAATAAATTTGACATGATTCTTTGTACAACGT
CAGTAACTCTTAAACAGGTGGTGACATTTTTTAATATAGCACAAGTGATT
ATTGATGAAGCCGGAATGTGTAAAGAACCTGAAACTTTGATTCCCATTGC
TGCAGCAGCAAAATCAGTTAAAAATGTCGTTTTGATTGGAGACCATAAAC
AGCTTCGTCCTATGATAAGAAGTCGTTTGGCTGATAAACGTGGATTGCAA
ATTTCTTTGTTTGAAAGGTATCAGAAATTAAAACCGGAATTAGTAACAAT
GTTAAATCTCCAGTATCGCATGCATCCTTCGATTTGTGACTTTCCTAGCA
TGGAATTTTATTCGGGCAAACTTATAACTCATGTGTCCCCATTGTGGTGT
GGATTGAAATCAGATCACATGAAAGTCTTTTGTCATTCATCCGACTCTTC
GAAAAAGAAAGAAGAGGTATACATCAACTGGAATGGAATAGATTATGAAA
AATCAGTTGATCATTACAAAGAATTTTTGAAAACATCAAATTACAACGCG
ATTCCTGATGCCAAATGGCCAGGTAAACGAAAAAGACCATTCCAATGTTT
TCATAAGAGATTTGAAGAGTATCCTGAACGAATAATTTTCATTGACGTTA
TTGGTGAAGAAATATCTCAATCAGTAACAACAACCACTGGAAATGAAAAG
TCGAAAGGCAACAAAGTTGAAGTGGAAGTAGTTGGATATATTTATAAAAA
ATTACTTGAAACTTGTTTTCCTCCTCGATTGGCTCCAAATTTTATTACTG
TTTTGACGCAATACAGTTATCAACAGCATTTATTGGAAATGGAGTGCAAG
TCCATTTTATTGAAAAAAACAACTACAAGTCCTATTGTTAAAACGGTTAT
TCGAAGTCAAGGCTCGGAAAACGATTATGTAATTTTTTCCACTGTTCGTT
CCATGAATATTGAAGATATAAATTACAATCCAACCTTTGGATGGGAACAA
AAGCATCTTGGATTTATTACAAATTTAAATCAGATCAATGTCGCTTTAAC
CAGGGCAAAAAAAGGCCTGATCATAATAGGTAACAAACGGTTATTGAAAG
TTAATCAGACCTGGAAGAAGTTGATAGAGAATTTGGAAGAGCGCAATTGT
GTTATTGCAGATTATTTAAATTTTATATGAGAATTTTATAGATTTATTTT
TATTTATGATTATTAGATTTTTCTTAATATTACACTTATTTTATATTCTG
TCAGATAATTCTTTATTTGATATCTTTCTATTTATGATATTTTATACACT
AATGTGAAC
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protein sequence of SMED30006144-orf-1

>SMED30006144-orf-1 ID=SMED30006144-orf-1|Name=SMED30006144-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1920bp
MNENEDNNRIKVKGKQETCKFSSPERDSQNDYYIQPESTNQEYSDFFVVS
IHADLEKKIYKDGNISIWMSYIIDDDIEYLVNERLKSLKKVAIGRIDCLW
SCLYNYLTKSNTKTDEYKDFHQLKSAFYLKCESLKKEKEDLDHVAMKYFA
NQYKMQLRFSSIDESLKEIIYGRNLLKSVHFLHIGLDLFLPLELNECKDH
YKFSNEEKTKLGELTNINEKKIEDKLKFKNEVKTLKNLNKLLKGLTRADS
YDFESMKRRGLQYDVYTPKQLDEMKDKLILCKLKINKSQSGLAIPIENLA
NKKFKEIILTSRQNCGFNVFLNDIVYVKIINEKFHSGKVMGVYQSFHKPV
NKLYVCKVSKDQGNLMVPLDKSFPKIHVENTAGRNLYKNKIKNENKTIST
EQESFLDKEKNRNSYADNTYFSLFDITGINQLTNMPIFGNCRCIEFSPDT
CEYLFVVLYQKWNPHFMYPYGRIVGTLSSQDSLQDSLPLIRAICNLNLLE
ISPKYEKEVKTIREKHMILDKPHITLPSGAIVFTIDNKTTKDMDDAISYH
REMNQIVIGVHISDVTKYVSPTSEMYKQAKDCFCTSYPPKYLNIPPYHIF
DEKLATDFLSLVPGKPRAVVSVLFKFSENMINDKNFKFSDIVQPEFREDV
IISKYKLNYEEVSLWLKQSDDPANVDADLYMALESVYKIARKIRHARLPY
SYFVRSVKNCYTNLQTENRFEAELLIEEFMLLANEYVARIIYEKYPNSTL
LRMQSPVKNREEWLENLHESTNLNFAGQLKEYCNLLGVLNFNRNSRQKFI
VSRKFFELFNEFIKQSDFDKAKCLLQYDEYFNEFYVHITDWYHISNPSYY
NCSEKDSVNMGHFSLNKSLYTHFTSPIRRFTDVVVHRLLKSVIHKIDIDD
CSLDIDEICVNANTKSKYNKNFEKLCEPYAIVEETNKRFCLILDCVCSEI
NDEEIICAHPLLQVASSDNRIKFANLSLDEVPVLSKSNENFGKCNLKWRK
IIFSCPPYLNSSSSNDNKFKIDSHLFDSYLPYSDSKLFQEIRRSYLSGEA
LENKLNQLCTKFVSYNYSNIISSDSFSFVEPIVDIELDMCVKNTMRIQFC
KYKASGLMQINPELFVVTPSFHICLIHQNNPSKFFISGGKLDLLHNNVKE
SFSSIKEYKDYFEPLIEDESLMEALSDRSAFTLEKVLIKWILGKSIKTKK
TERYGVITLSSDFCNLRSDIFHKEIYKIFNRYEYLIASGISSVGGDLLCL
RCRKEDWNNYWVGHGHVVTINKCMINNQKMKLIIFRLTQSNFDLPKSAEN
VNFTLDIYQKSIVSIRQQVIMNKIDKIELLKEVILGAETNKKINNPTEKI
IAQIENELNWKKFNRNQYNAVKNALNQKLSLIWGPPGTGKTMVGCYLSFA
YTFVNRKENKNSVVLYCGPSNDCINLVASTMMEKFNEKCPKLLRIFGKEQ
EVSDFPIPGHFFKNKTLPIDIQEVSLHFLIRKNGGYADELKKFDNIFKCI
RNKDPIPPDFNVYNAILTYKNLVKKAKKEYIVKNKFDMILCTTSVTLKQV
VTFFNIAQVIIDEAGMCKEPETLIPIAAAAKSVKNVVLIGDHKQLRPMIR
SRLADKRGLQISLFERYQKLKPELVTMLNLQYRMHPSICDFPSMEFYSGK
LITHVSPLWCGLKSDHMKVFCHSSDSSKKKEEVYINWNGIDYEKSVDHYK
EFLKTSNYNAIPDAKWPGKRKRPFQCFHKRFEEYPERIIFIDVIGEEISQ
SVTTTTGNEKSKGNKVEVEVVGYIYKKLLETCFPPRLAPNFITVLTQYSY
QQHLLEMECKSILLKKTTTSPIVKTVIRSQGSENDYVIFSTVRSMNIEDI
NYNPTFGWEQKHLGFITNLNQINVALTRAKKGLIIIGNKRLLKVNQTWKK
LIENLEERNCVIADYLNFI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0004540ribonuclease activity
GO:0004386helicase activity
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0090501RNA phosphodiester bond hydrolysis
GO:1903506regulation of nucleic acid-templated transcription
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR001900RNase_II/R
IPR041677DNA2/NAM7_AAA_11
IPR041679DNA2/NAM7-like_AAA
IPR027417P-loop_NTPase
IPR022966RNase_II/R_CS
IPR012340NA-bd_OB-fold
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 1888..1908
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 1288..1631
e-value: 7.5E-48
score: 165.3
NoneNo IPR availablePANTHERPTHR43788:SF9SI:DKEY-97A13.6coord: 1736..1913
NoneNo IPR availablePANTHERPTHR43788FAMILY NOT NAMEDcoord: 1736..1913
NoneNo IPR availablePANTHERPTHR43788:SF9SI:DKEY-97A13.6coord: 303..1656
NoneNo IPR availablePANTHERPTHR43788FAMILY NOT NAMEDcoord: 303..1656
NoneNo IPR availableCDDcd18808SF1_C_Upf1coord: 1634..1906
e-value: 8.11305E-38
score: 138.906
NoneNo IPR availableCDDcd18040DEXXc_HELZ2-Ccoord: 1362..1633
e-value: 5.73092E-63
score: 214.311
IPR001900Ribonuclease II/RSMARTSM00955RNB_2coord: 523..895
e-value: 1.0E-44
score: 164.6
IPR001900Ribonuclease II/RPFAMPF00773RNBcoord: 531..894
e-value: 6.7E-55
score: 186.7
IPR041677DNA2/NAM7 helicase, AAA domainPFAMPF13086AAA_11coord: 1362..1601
e-value: 4.6E-35
score: 121.7
IPR041679DNA2/NAM7 helicase-like, AAA domainPFAMPF13087AAA_12coord: 1610..1889
e-value: 7.4E-44
score: 149.8
IPR022966Ribonuclease II/R, conserved sitePROSITEPS01175RIBONUCLEASE_IIcoord: 862..886
IPR012340Nucleic acid-binding, OB-foldSUPERFAMILYSSF50249Nucleic acid-binding proteinscoord: 453..930
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 1361..1902