E3 ubiquitin-protein ligase HECTD1

Overview
NameE3 ubiquitin-protein ligase HECTD1
Smed IDSMED30006114
Length (bp)8332
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of E3 ubiquitin-protein ligase HECTD1 (SMED30006114) t-SNE clustered cells

Violin plots show distribution of expression levels for E3 ubiquitin-protein ligase HECTD1 (SMED30006114) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of E3 ubiquitin-protein ligase HECTD1 (SMED30006114) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for E3 ubiquitin-protein ligase HECTD1 (SMED30006114) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30006114

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 16

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30006114SMESG000022351.1 SMESG000022345.1 dd_Smed_v4_17106_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30006114SMESG000022351.1 SMESG000022345.1 dd_Smed_v4_17106_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30006114SMESG000022345.1 Contig54875newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022345.1 Contig54875uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022345.1 Contig13813newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022345.1 Contig13813uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022351.1 Contig21182newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022351.1 Contig21182uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022351.1 Contig40488newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022351.1 Contig40488uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022345.1 Contig20368newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022345.1 Contig20368uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022351.1 Contig42053newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30006114SMESG000022351.1 Contig42053uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
neoblastSMED30006114SMESG000022351.1 KP954681smed_ncbi_20200123PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymal cellSMED30006114SMESG000022351.1 KP954681smed_ncbi_20200123PMID:25956527
Henderson et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Human
Match: HECTD1 (HECT domain E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:20157])

HSP 1 Score: 278.1 bits (710), Expect = 2.347e-76
Identity = 199/612 (32.52%), Postives = 303/612 (49.51%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIR--PSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDL----PFSELFL-------------------EILCKD------------------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHD-QLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R   S R D    F  +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R  L  W+  D+F ++E+              +V    GLF  P+P D    E + K F  LGIF+AK +QDNR++DL    PF +L                     ++ C +                  F + +K E++                  + F L+ P R  FL  I+    +++++L     + +    K+ +  LK  +      + + L L+ +F P+S+IYG         +   D   S +D            E +T +NAE Y+    +F M+ GI+KQ     DGFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct:  402 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDDPGEFR-VGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSGPPLSIEDLGLNFQFCPSSRIYG---------FTAVDLKPSGED------------EMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 976
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Human
Match: HECTD1 (HECT domain E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:20157])

HSP 1 Score: 284.648 bits (727), Expect = 6.003e-76
Identity = 200/614 (32.57%), Postives = 305/614 (49.67%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLPFSELFLEIL-----------------------CKD------------------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHD-QLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R  L  W+  D+F ++E+              +V    GLF  P+P D    E + K F  LGIF+AK +QDNR++DLP S+ F +++                       C +                  F + +K E++                  + F L+ P R  FL  I+    +++++L     + +    K+ +  LK  +      + + L L+ +F P+S+IYG     L           S +D            E +T +NAE Y+    +F M+ GI+KQ     DGFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2040 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDL---------KPSGED------------EMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2614

HSP 2 Score: 107.071 bits (266), Expect = 5.714e-22
Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPS*FCTENASTS 892
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL       +M         PS  C    ST+
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELLS------RMAAAGGTVSGPSSACKPGRSTT 261

HSP 3 Score: 72.0182 bits (175), Expect = 2.085e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Human
Match: HECTD1 (HECT domain E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:20157])

HSP 1 Score: 284.263 bits (726), Expect = 8.907e-76
Identity = 200/614 (32.57%), Postives = 305/614 (49.67%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLPFSELFLEIL-----------------------CKD------------------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHD-QLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R  L  W+  D+F ++E+              +V    GLF  P+P D    E + K F  LGIF+AK +QDNR++DLP S+ F +++                       C +                  F + +K E++                  + F L+ P R  FL  I+    +++++L     + +    K+ +  LK  +      + + L L+ +F P+S+IYG     L           S +D            E +T +NAE Y+    +F M+ GI+KQ     DGFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2036 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDL---------KPSGED------------EMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2610

HSP 2 Score: 107.071 bits (266), Expect = 5.712e-22
Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPS*FCTENASTS 892
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL       +M         PS  C    ST+
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELLS------RMAAAGGTVSGPSSACKPGRSTT 261

HSP 3 Score: 72.0182 bits (175), Expect = 2.084e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Human
Match: HECTD1 (HECT domain E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:20157])

HSP 1 Score: 284.263 bits (726), Expect = 8.907e-76
Identity = 200/614 (32.57%), Postives = 305/614 (49.67%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLPFSELFLEIL-----------------------CKD------------------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHD-QLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R  L  W+  D+F ++E+              +V    GLF  P+P D    E + K F  LGIF+AK +QDNR++DLP S+ F +++                       C +                  F + +K E++                  + F L+ P R  FL  I+    +++++L     + +    K+ +  LK  +      + + L L+ +F P+S+IYG     L           S +D            E +T +NAE Y+    +F M+ GI+KQ     DGFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2036 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDL---------KPSGED------------EMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2610

HSP 2 Score: 107.071 bits (266), Expect = 5.712e-22
Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPS*FCTENASTS 892
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL       +M         PS  C    ST+
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELLS------RMAAAGGTVSGPSSACKPGRSTT 261

HSP 3 Score: 72.0182 bits (175), Expect = 2.084e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Human
Match: TRIP12 (thyroid hormone receptor interactor 12 [Source:HGNC Symbol;Acc:HGNC:12306])

HSP 1 Score: 187.963 bits (476), Expect = 1.043e-46
Identity = 149/526 (28.33%), Postives = 245/526 (46.58%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFL------EEENEFVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVP-FPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVK-----DGPYPSVNTCMHYLKLP 7569
            FI+  +  K   QL+D   +++ + +P+W+ E  +  PF F +D +  +     F   R+   +Q+    N +  +   +D  VAP     RL +    + R       +L +AES       ++DL      S+  LEIQ++ E GTGLGPTLEF  ++S+E  R  L +W   +  L      +E  +++ +  GLF  P+        + +   KFR LG  MAK++ D R++DLP    F + + +  +     +       I P     +  +E    +K++L +      +++  K   Q     + + G + + L LD           T+P FP                  N+  +K     PVT +N E YL+  + +A+N+G+ +QF    DGF  VFP+  L  F   EL QLLCG +   W    L     P  GY   S++ ++  E+L   +  ++++F+QF++G   LP GG ++L P LTIV+K  +     D   PSV TC++YLKLP
Sbjct: 1233 FINSKLTAKANRQLQDPLVIMTGN-IPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRA---MQRLLDTNPEINQSDSQDSRVAP-----RLDRKKRTVNR-----EELLKQAES------VMQDL----GSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFD----IDPVVARSVYHLEDIVRQKKRLEQ------DKSQTKESLQYALETLTMNGCSVEDLGLDF----------TLPGFP------------------NIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLP 1696
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Celegans
Match: hecd-1 (E3 ubiquitin-protein ligase hecd-1 [Source:UniProtKB/Swiss-Prot;Acc:V6CLA2])

HSP 1 Score: 292.352 bits (747), Expect = 1.027e-78
Identity = 203/571 (35.55%), Postives = 290/571 (50.79%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFR--DDLVAPFH------FLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTD-----SFLEEENE------------FVFSKNGLFPYPWP-ADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCK-DFSDYNKKEYLKR------FMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTT--FDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            FIS  +  KV   L D   + +R +LP W      KYP +F  + +   ++A  FGVSR+++WLQQR     +  R S +  +   A  H       +GRL+    ++ R               ++   A+R L+ FHA  K  LEI++  EEGTGLGPTLEF  +++ E  R SL +WV  D     S   EE E            +V    GLFP P P     T+   + FR+LG+F+AK L D R++DLP S  FL++L      D  +   L +      F  + P +G FL  +    + K+ +    +   N    K+ +    L + I G+T   + L L+    P SK++      L D                 G + D     VT +N E Y+++   F +N GI  Q     DGF+ VFP+++L  +S  E+++LL GEQ  +WS  ++ NYTEP  GY   S  +  F++V+  L   ERK F+QF +GCSSLPPGGL NL PRLTIV+K    DG YPSVNTC+HYLKLPEY + + L+ +LL A N+ GF+LN
Sbjct: 2082 FISDKLTLKVTQVLSDALVVAAR-SLPEWCSRLVYKYPCLFTVETRNMYMQATAFGVSRTIVWLQQRRDAAVERARGSAQAGNSSAARQHDRYHEYRVGRLRHERVKVTRA------------EETLLDQAIR-LMKFHADRKAVLEIEYTNEEGTGLGPTLEFYALVAAELQRKSLALWVCDDDDTHASKSGEEREVDLGEGKKPIGYYVRRVGGLFPAPLPPGTDETKRAADMFRVLGVFLAKVLLDGRLVDLPLSRPFLKLLVHPQIGDDARGPNLHKILSLDDFEEVNPVKGSFLKELRALAQRKRLIENDTSIDSNSKRRKIAE----LKLHIKGSTCRVEDLALNFTVNPPSKVFQYAEMELVDG----------------GSDID-----VTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFDRVFPLRTLRAYSPEEVQRLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEALTAQERKNFLQFATGCSSLPPGGLANLHPRLTIVRKVESGDGSYPSVNTCVHYLKLPEYSSSAILRERLLTAINEKGFHLN 2613

HSP 2 Score: 103.605 bits (257), Expect = 2.100e-21
Identity = 73/258 (28.29%), Postives = 137/258 (53.10%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSG---SEEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIE-KIIDDLLEMTMVQLKMDNQTSHNQN 856
            MD ++ P  LL WLQ+G     ++QL ALEQLC+ LL  ++ +   +  PP T+IP L  +  D      +LE   R +TYY+  + +E   R+    G++ AIC RL   ++++    DL +Q +KLLE +C+R+T ++ + GG + +++ +      +H DT+ S   ++ ++  K++P+D  L +  E L    +H D K+ E +L C  ++      K +    L +   +++ L+ + +     ++ T+ + N
Sbjct:    1 MDGID-PETLLEWLQTGIGDERDLQLMALEQLCMLLLMADNIDRCFESCPPRTFIPALCKIFIDETAPDNVLEVTARAITYYLD-VSNECTRRITQVDGAVKAICTRLAAADISDRSSKDLAEQCVKLLEHVCQRETMAVYDAGGINAMLTLVRVHGTQVHKDTMHSAMSVVTRLCGKMEPTDPELGKCAESLGALLEHEDPKVSESALRCFAALTDRFVRKMMDPAELAMHSNLVEHLISIMVASNDENSPTTASAN 256
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Celegans
Match: hecd-1 (E3 ubiquitin-protein ligase hecd-1 [Source:UniProtKB/Swiss-Prot;Acc:V6CLA2])

HSP 1 Score: 292.352 bits (747), Expect = 1.035e-78
Identity = 203/571 (35.55%), Postives = 290/571 (50.79%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFR--DDLVAPFH------FLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTD-----SFLEEENE------------FVFSKNGLFPYPWP-ADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCK-DFSDYNKKEYLKR------FMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTT--FDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            FIS  +  KV   L D   + +R +LP W      KYP +F  + +   ++A  FGVSR+++WLQQR     +  R S +  +   A  H       +GRL+    ++ R               ++   A+R L+ FHA  K  LEI++  EEGTGLGPTLEF  +++ E  R SL +WV  D     S   EE E            +V    GLFP P P     T+   + FR+LG+F+AK L D R++DLP S  FL++L      D  +   L +      F  + P +G FL  +    + K+ +    +   N    K+ +    L + I G+T   + L L+    P SK++      L D                 G + D     VT +N E Y+++   F +N GI  Q     DGF+ VFP+++L  +S  E+++LL GEQ  +WS  ++ NYTEP  GY   S  +  F++V+  L   ERK F+QF +GCSSLPPGGL NL PRLTIV+K    DG YPSVNTC+HYLKLPEY + + L+ +LL A N+ GF+LN
Sbjct: 2080 FISDKLTLKVTQVLSDALVVAAR-SLPEWCSRLVYKYPCLFTVETRNMYMQATAFGVSRTIVWLQQRRDAAVERARGSAQAGNSSAARQHDRYHEYRVGRLRHERVKVTRA------------EETLLDQAIR-LMKFHADRKAVLEIEYTNEEGTGLGPTLEFYALVAAELQRKSLALWVCDDDDTHASKSGEEREVDLGEGKKPIGYYVRRVGGLFPAPLPPGTDETKRAADMFRVLGVFLAKVLLDGRLVDLPLSRPFLKLLVHPQIGDDARGPNLHKILSLDDFEEVNPVKGSFLKELRALAQRKRLIENDTSIDSNSKRRKIAE----LKLHIKGSTCRVEDLALNFTVNPPSKVFQYAEMELVDG----------------GSDID-----VTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFDRVFPLRTLRAYSPEEVQRLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEALTAQERKNFLQFATGCSSLPPGGLANLHPRLTIVRKVESGDGSYPSVNTCVHYLKLPEYSSSAILRERLLTAINEKGFHLN 2611

HSP 2 Score: 103.605 bits (257), Expect = 2.099e-21
Identity = 73/258 (28.29%), Postives = 137/258 (53.10%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSG---SEEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIE-KIIDDLLEMTMVQLKMDNQTSHNQN 856
            MD ++ P  LL WLQ+G     ++QL ALEQLC+ LL  ++ +   +  PP T+IP L  +  D      +LE   R +TYY+  + +E   R+    G++ AIC RL   ++++    DL +Q +KLLE +C+R+T ++ + GG + +++ +      +H DT+ S   ++ ++  K++P+D  L +  E L    +H D K+ E +L C  ++      K +    L +   +++ L+ + +     ++ T+ + N
Sbjct:    1 MDGID-PETLLEWLQTGIGDERDLQLMALEQLCMLLLMADNIDRCFESCPPRTFIPALCKIFIDETAPDNVLEVTARAITYYLD-VSNECTRRITQVDGAVKAICTRLAAADISDRSSKDLAEQCVKLLEHVCQRETMAVYDAGGINAMLTLVRVHGTQVHKDTMHSAMSVVTRLCGKMEPTDPELGKCAESLGALLEHEDPKVSESALRCFAALTDRFVRKMMDPAELAMHSNLVEHLISIMVASNDENSPTTASAN 256
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Celegans
Match: hecd-1 (E3 ubiquitin-protein ligase hecd-1 [Source:UniProtKB/Swiss-Prot;Acc:V6CLA2])

HSP 1 Score: 292.352 bits (747), Expect = 1.035e-78
Identity = 203/571 (35.55%), Postives = 290/571 (50.79%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFR--DDLVAPFH------FLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTD-----SFLEEENE------------FVFSKNGLFPYPWP-ADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCK-DFSDYNKKEYLKR------FMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTT--FDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            FIS  +  KV   L D   + +R +LP W      KYP +F  + +   ++A  FGVSR+++WLQQR     +  R S +  +   A  H       +GRL+    ++ R               ++   A+R L+ FHA  K  LEI++  EEGTGLGPTLEF  +++ E  R SL +WV  D     S   EE E            +V    GLFP P P     T+   + FR+LG+F+AK L D R++DLP S  FL++L      D  +   L +      F  + P +G FL  +    + K+ +    +   N    K+ +    L + I G+T   + L L+    P SK++      L D                 G + D     VT +N E Y+++   F +N GI  Q     DGF+ VFP+++L  +S  E+++LL GEQ  +WS  ++ NYTEP  GY   S  +  F++V+  L   ERK F+QF +GCSSLPPGGL NL PRLTIV+K    DG YPSVNTC+HYLKLPEY + + L+ +LL A N+ GF+LN
Sbjct: 2080 FISDKLTLKVTQVLSDALVVAAR-SLPEWCSRLVYKYPCLFTVETRNMYMQATAFGVSRTIVWLQQRRDAAVERARGSAQAGNSSAARQHDRYHEYRVGRLRHERVKVTRA------------EETLLDQAIR-LMKFHADRKAVLEIEYTNEEGTGLGPTLEFYALVAAELQRKSLALWVCDDDDTHASKSGEEREVDLGEGKKPIGYYVRRVGGLFPAPLPPGTDETKRAADMFRVLGVFLAKVLLDGRLVDLPLSRPFLKLLVHPQIGDDARGPNLHKILSLDDFEEVNPVKGSFLKELRALAQRKRLIENDTSIDSNSKRRKIAE----LKLHIKGSTCRVEDLALNFTVNPPSKVFQYAEMELVDG----------------GSDID-----VTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFDRVFPLRTLRAYSPEEVQRLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEALTAQERKNFLQFATGCSSLPPGGLANLHPRLTIVRKVESGDGSYPSVNTCVHYLKLPEYSSSAILRERLLTAINEKGFHLN 2611

HSP 2 Score: 103.605 bits (257), Expect = 2.099e-21
Identity = 73/258 (28.29%), Postives = 137/258 (53.10%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSG---SEEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIE-KIIDDLLEMTMVQLKMDNQTSHNQN 856
            MD ++ P  LL WLQ+G     ++QL ALEQLC+ LL  ++ +   +  PP T+IP L  +  D      +LE   R +TYY+  + +E   R+    G++ AIC RL   ++++    DL +Q +KLLE +C+R+T ++ + GG + +++ +      +H DT+ S   ++ ++  K++P+D  L +  E L    +H D K+ E +L C  ++      K +    L +   +++ L+ + +     ++ T+ + N
Sbjct:    1 MDGID-PETLLEWLQTGIGDERDLQLMALEQLCMLLLMADNIDRCFESCPPRTFIPALCKIFIDETAPDNVLEVTARAITYYLD-VSNECTRRITQVDGAVKAICTRLAAADISDRSSKDLAEQCVKLLEHVCQRETMAVYDAGGINAMLTLVRVHGTQVHKDTMHSAMSVVTRLCGKMEPTDPELGKCAESLGALLEHEDPKVSESALRCFAALTDRFVRKMMDPAELAMHSNLVEHLISIMVASNDENSPTTASAN 256
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Celegans
Match: hecd-1 (E3 ubiquitin-protein ligase hecd-1 [Source:UniProtKB/Swiss-Prot;Acc:V6CLA2])

HSP 1 Score: 292.352 bits (747), Expect = 1.255e-78
Identity = 203/571 (35.55%), Postives = 290/571 (50.79%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFR--DDLVAPFH------FLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTD-----SFLEEENE------------FVFSKNGLFPYPWP-ADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCK-DFSDYNKKEYLKR------FMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTT--FDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            FIS  +  KV   L D   + +R +LP W      KYP +F  + +   ++A  FGVSR+++WLQQR     +  R S +  +   A  H       +GRL+    ++ R               ++   A+R L+ FHA  K  LEI++  EEGTGLGPTLEF  +++ E  R SL +WV  D     S   EE E            +V    GLFP P P     T+   + FR+LG+F+AK L D R++DLP S  FL++L      D  +   L +      F  + P +G FL  +    + K+ +    +   N    K+ +    L + I G+T   + L L+    P SK++      L D                 G + D     VT +N E Y+++   F +N GI  Q     DGF+ VFP+++L  +S  E+++LL GEQ  +WS  ++ NYTEP  GY   S  +  F++V+  L   ERK F+QF +GCSSLPPGGL NL PRLTIV+K    DG YPSVNTC+HYLKLPEY + + L+ +LL A N+ GF+LN
Sbjct: 2119 FISDKLTLKVTQVLSDALVVAAR-SLPEWCSRLVYKYPCLFTVETRNMYMQATAFGVSRTIVWLQQRRDAAVERARGSAQAGNSSAARQHDRYHEYRVGRLRHERVKVTRA------------EETLLDQAIR-LMKFHADRKAVLEIEYTNEEGTGLGPTLEFYALVAAELQRKSLALWVCDDDDTHASKSGEEREVDLGEGKKPIGYYVRRVGGLFPAPLPPGTDETKRAADMFRVLGVFLAKVLLDGRLVDLPLSRPFLKLLVHPQIGDDARGPNLHKILSLDDFEEVNPVKGSFLKELRALAQRKRLIENDTSIDSNSKRRKIAE----LKLHIKGSTCRVEDLALNFTVNPPSKVFQYAEMELVDG----------------GSDID-----VTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFDRVFPLRTLRAYSPEEVQRLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEALTAQERKNFLQFATGCSSLPPGGLANLHPRLTIVRKVESGDGSYPSVNTCVHYLKLPEYSSSAILRERLLTAINEKGFHLN 2650

HSP 2 Score: 103.605 bits (257), Expect = 2.106e-21
Identity = 73/258 (28.29%), Postives = 137/258 (53.10%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSG---SEEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIE-KIIDDLLEMTMVQLKMDNQTSHNQN 856
            MD ++ P  LL WLQ+G     ++QL ALEQLC+ LL  ++ +   +  PP T+IP L  +  D      +LE   R +TYY+  + +E   R+    G++ AIC RL   ++++    DL +Q +KLLE +C+R+T ++ + GG + +++ +      +H DT+ S   ++ ++  K++P+D  L +  E L    +H D K+ E +L C  ++      K +    L +   +++ L+ + +     ++ T+ + N
Sbjct:    1 MDGID-PETLLEWLQTGIGDERDLQLMALEQLCMLLLMADNIDRCFESCPPRTFIPALCKIFIDETAPDNVLEVTARAITYYLD-VSNECTRRITQVDGAVKAICTRLAAADISDRSSKDLAEQCVKLLEHVCQRETMAVYDAGGINAMLTLVRVHGTQVHKDTMHSAMSVVTRLCGKMEPTDPELGKCAESLGALLEHEDPKVSESALRCFAALTDRFVRKMMDPAELAMHSNLVEHLISIMVASNDENSPTTASAN 256

HSP 3 Score: 68.1662 bits (165), Expect = 1.054e-10
Identity = 45/140 (32.14%), Postives = 71/140 (50.71%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINNQTMDFYVKDVEGITVTERLEQFIKLNSN--PNKIEEINDFILKIENQKLNVKT 1871
            H  L+ AI   ++  L + + S   D NF D  GQ+  NWASA G +E V  L  +G D N G + +SLHYAA  G   V+K L+  +  +  ++D +G T  ++  +    + N   N +E  + F+   E+ K+   T
Sbjct:  342 HRQLIDAIRQKDLTALVDAIESGQVDVNFADDVGQSLTNWASAFGSIEMVQYLCDKGSDVNKGHKSSSLHYAACFGRPDVVKLLL-QRGANPDLRDEDGKTALDKARERSDDDHNQVANILESPSAFMRNKEDPKVKAST 480
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Celegans
Match: hecd-1 (E3 ubiquitin-protein ligase hecd-1 [Source:UniProtKB/Swiss-Prot;Acc:V6CLA2])

HSP 1 Score: 292.352 bits (747), Expect = 1.308e-78
Identity = 203/571 (35.55%), Postives = 290/571 (50.79%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFR--DDLVAPFH------FLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTD-----SFLEEENE------------FVFSKNGLFPYPWP-ADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCK-DFSDYNKKEYLKR------FMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTT--FDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            FIS  +  KV   L D   + +R +LP W      KYP +F  + +   ++A  FGVSR+++WLQQR     +  R S +  +   A  H       +GRL+    ++ R               ++   A+R L+ FHA  K  LEI++  EEGTGLGPTLEF  +++ E  R SL +WV  D     S   EE E            +V    GLFP P P     T+   + FR+LG+F+AK L D R++DLP S  FL++L      D  +   L +      F  + P +G FL  +    + K+ +    +   N    K+ +    L + I G+T   + L L+    P SK++      L D                 G + D     VT +N E Y+++   F +N GI  Q     DGF+ VFP+++L  +S  E+++LL GEQ  +WS  ++ NYTEP  GY   S  +  F++V+  L   ERK F+QF +GCSSLPPGGL NL PRLTIV+K    DG YPSVNTC+HYLKLPEY + + L+ +LL A N+ GF+LN
Sbjct: 2117 FISDKLTLKVTQVLSDALVVAAR-SLPEWCSRLVYKYPCLFTVETRNMYMQATAFGVSRTIVWLQQRRDAAVERARGSAQAGNSSAARQHDRYHEYRVGRLRHERVKVTRA------------EETLLDQAIR-LMKFHADRKAVLEIEYTNEEGTGLGPTLEFYALVAAELQRKSLALWVCDDDDTHASKSGEEREVDLGEGKKPIGYYVRRVGGLFPAPLPPGTDETKRAADMFRVLGVFLAKVLLDGRLVDLPLSRPFLKLLVHPQIGDDARGPNLHKILSLDDFEEVNPVKGSFLKELRALAQRKRLIENDTSIDSNSKRRKIAE----LKLHIKGSTCRVEDLALNFTVNPPSKVFQYAEMELVDG----------------GSDID-----VTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFDRVFPLRTLRAYSPEEVQRLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEALTAQERKNFLQFATGCSSLPPGGLANLHPRLTIVRKVESGDGSYPSVNTCVHYLKLPEYSSSAILRERLLTAINEKGFHLN 2648

HSP 2 Score: 103.605 bits (257), Expect = 2.105e-21
Identity = 73/258 (28.29%), Postives = 137/258 (53.10%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSG---SEEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIE-KIIDDLLEMTMVQLKMDNQTSHNQN 856
            MD ++ P  LL WLQ+G     ++QL ALEQLC+ LL  ++ +   +  PP T+IP L  +  D      +LE   R +TYY+  + +E   R+    G++ AIC RL   ++++    DL +Q +KLLE +C+R+T ++ + GG + +++ +      +H DT+ S   ++ ++  K++P+D  L +  E L    +H D K+ E +L C  ++      K +    L +   +++ L+ + +     ++ T+ + N
Sbjct:    1 MDGID-PETLLEWLQTGIGDERDLQLMALEQLCMLLLMADNIDRCFESCPPRTFIPALCKIFIDETAPDNVLEVTARAITYYLD-VSNECTRRITQVDGAVKAICTRLAAADISDRSSKDLAEQCVKLLEHVCQRETMAVYDAGGINAMLTLVRVHGTQVHKDTMHSAMSVVTRLCGKMEPTDPELGKCAESLGALLEHEDPKVSESALRCFAALTDRFVRKMMDPAELAMHSNLVEHLISIMVASNDENSPTTASAN 256

HSP 3 Score: 68.1662 bits (165), Expect = 1.054e-10
Identity = 45/140 (32.14%), Postives = 71/140 (50.71%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINNQTMDFYVKDVEGITVTERLEQFIKLNSN--PNKIEEINDFILKIENQKLNVKT 1871
            H  L+ AI   ++  L + + S   D NF D  GQ+  NWASA G +E V  L  +G D N G + +SLHYAA  G   V+K L+  +  +  ++D +G T  ++  +    + N   N +E  + F+   E+ K+   T
Sbjct:  342 HRQLIDAIRQKDLTALVDAIESGQVDVNFADDVGQSLTNWASAFGSIEMVQYLCDKGSDVNKGHKSSSLHYAACFGRPDVVKLLL-QRGANPDLRDEDGKTALDKARERSDDDHNQVANILESPSAFMRNKEDPKVKAST 480
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Fly
Match: Ufd4 (gene:FBgn0032208 transcript:FBtr0080074)

HSP 1 Score: 269.24 bits (687), Expect = 1.459e-71
Identity = 211/705 (29.93%), Postives = 321/705 (45.53%), Query Frame = 1 
Query: 5761 IDNVSEIWHSQFTLFYGFCDKKGPGTSCQNC--FYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVD----------WLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFH-----FLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFS---------------KNGLFPYPWPAD-KLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKD------------------------------------FSDYNKKEY------LKRFMLIYPERGLFLMSIELFCEEKQKLL--KTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            +D   +IW   +T+ Y     +   ++C     F Q    S+++      P + +   F++  +  CS    +E    Q+  L   ++D            +  FIS+ +  K+  Q++D   L S + LP+W     Q  PF+F ++ +        FG SRS++ LQ +     D      R  +++P        +GRLK    ++PR                + W+    ++  H   K  LE++F  EEGTGLGPTLEF  +++ E  R  L MW+  D   E+      S               ++G+FP P P + ++ E +L+ F   G+F+AK LQD R++D+P S  FL++LC +                                     +D NK         L+    I P R  FL  ++     KQ +    TI+      L    ++LK         + + L L   +LP+S IYG     L                       +     VT +N E Y +  +NF +  GI +Q     DGFNEVFP+K L+ F+ SE + ++CGEQ   WS  ++ +YTEP  GY   S  +Q F+ VLL ++  ERK F+QF +GCSSLPPGGL NL PRLT+V+K +   G YPSVNTC+HYLKLP+Y T+  +K +LL A  + GF+LN
Sbjct: 2067 LDKFRKIWEPTYTIVYREVSPEAQESTCLESEEFPQTPDVSSKSGASTLSPNSPMHIGFNVADNNLCSVDDVLELL-TQINGLNQSEIDSDVKEHGVSVLSEDLFISKKITNKLQQQIQDPLVLAS-NALPNWCENLNQSCPFLFPFETRQLYFNCTSFGASRSIVCLQSQ----RDVTVERQRIPIMSPRRDDHEFRIGRLKHERVKVPRNEDL------------LMWAM--QVMKTHCNRKSVLEVEFLDEEGTGLGPTLEFYALVAAEIQRSDLCMWLCDDDLGEDTENSTQSAEGNSKPVGYYVNRREHGIFPAPLPQNSEICENVLKYFWFFGVFVAKVLQDMRLVDIPLSTSFLQLLCHNKVLSRNLQKVISDRRNGDLSVVSEDSDIVETCTKLLRTDSNKSNAFGGILSLENLKEIDPTRYQFLQEMQNLLLRKQSIEFDDTISAEKKHELI---NELKLQTQNGLEVSLEDLALTFTYLPSSSIYGYTQAELL---------------------PNGSSVNVTIDNLEAYCELLMNFILQDGIAQQMKAFSDGFNEVFPLKKLAAFTPSEARMMICGEQFPHWSREDIISYTEPKLGYNKDSPGFQRFVNVLLSMSGDERKAFLQFTTGCSSLPPGGLANLHPRLTVVRKVDAGVGSYPSVNTCVHYLKLPDYPTEEIMKERLLTATKEKGFHLN 2727

HSP 2 Score: 90.5077 bits (223), Expect = 2.489e-17
Identity = 68/215 (31.63%), Postives = 114/215 (53.02%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSI 730
            M DV+ P  LL WL  G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V+  G++ AIC  L   ++++    DL +Q IK+LE +C R+  ++   GG + V+SF+      +H DT+ S   ++ ++  K++P+   +    E LS   +H D  + + +L C  S+
Sbjct:    1 MGDVD-PETLLEWLSMGQGDERDMQLIALEQLCMLLLMSDNVDRCFESCPPRTFLPALCKIFLDELAPENVLEVTARAITYYLD-VSAECTRRIVSIDGAIKAICNHLVVADLSSRTSRDLAEQCIKVLELICTREAGAVFEGGGLNCVLSFIRDCGSQVHKDTLHSAMSVVSRLCTKVEPNTPCIQNCVESLSTLLQHEDPMVSDGALKCFASV 213

HSP 3 Score: 75.0998 bits (183), Expect = 1.222e-12
Identity = 56/183 (30.60%), Postives = 86/183 (46.99%), Query Frame = 3 
Query: 1167 VIIDLILCIIRGSHQFLHNLLVKSKLVDIILEITWQYDSSSISILQLIEGM-FDQIMERTTYKSNENIQRYKLSTALGMRVIHNRMYSEEMIQQYWNYHEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALI 1712
              I L+  + RGS    H++L +S+L D  LE   Q D   +     ++ M F  ++    ++  + + R   +   G      R  +    +     H  L+  I + + + L+E + S   D N  D  GQT LNWASA G LE V  L  +G D N G+R +SLHYAA  G  ++ K L+
Sbjct:  303 TTISLLSTLCRGSPSITHDIL-RSQLADA-LERALQGDERCV-----LDCMRFADLLLLLLFEGRQALNRGSNNPNQGQLAPRPRRNNTNTDR----THRQLIDCIRSKDSEALREAIESGGIDVNCMDDVGQTLLNWASAFGTLEMVEYLCEKGADVNKGQRSSSLHYAACFGRPAIAKILL 474
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Fly
Match: ctrip (gene:FBgn0260794 transcript:FBtr0334902)

HSP 1 Score: 149.443 bits (376), Expect = 3.881e-35
Identity = 108/365 (29.59%), Postives = 181/365 (49.59%), Query Frame = 1 
Query: 6589 FVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCG----EQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGP-----YPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQ--IGFYLN 7641
            +V + +GLFP P        ++ +   KF+ LG FMAK++ D+R++DLPFS  F   L  +         L   M + PE    L+ ++    +++ +L   N        K+                    LD++  P + +   + F L  H        ++ ++C  G  +D+   PVT +N   Y+     + + +G++KQF  + +GF+ VFPI+ L MF   EL+ + CG    +QH +W +  LQ       G+   S++ QY  E+L   N+ E++ F+QF++G   LP GG K L P LTIV+K + +        PSV TC++YLKLP+Y ++  ++ KL  A N+  + F+L+
Sbjct: 2409 YVHAVHGLFPLPLGKSSKLPQMTKAKAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIG----LADLMRVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQ------------------LDLDGCPIADL--GLDFVLPGH--------ANIELCRGG--RDT---PVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGSGSEQQHSRWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLPTGGFKALTPPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANEGSMSFHLS 2736

HSP 2 Score: 64.6994 bits (156), Expect = 1.858e-9
Identity = 53/178 (29.78%), Postives = 82/178 (46.07%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSF 6570
            FI   +  K   QL+D   +++ + LP W+ +     PF+F ++ +  +  A  F   R++    QR    +  +  +   + VAP     RL +    I R       IL +AE           +L     SK  LEIQ++ E GTGLGPTLEF  ++S E  R  L +W  +DS+
Sbjct: 2112 FIHPKIMAKANRQLQDPLVIMTGN-LPQWLPQIGMACPFLFPFETRHLLFYATSFDRDRAL----QRLLDTTPDLNAAESSERVAP-----RLDRRKRAISR-----TEILKQAEH----------ILQDFGHSKALLEIQYENEVGTGLGPTLEFYALVSAELQRTDLGLWNGSDSY 2264
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Fly
Match: ctrip (gene:FBgn0260794 transcript:FBtr0303917)

HSP 1 Score: 149.443 bits (376), Expect = 3.881e-35
Identity = 108/365 (29.59%), Postives = 181/365 (49.59%), Query Frame = 1 
Query: 6589 FVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCG----EQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGP-----YPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQ--IGFYLN 7641
            +V + +GLFP P        ++ +   KF+ LG FMAK++ D+R++DLPFS  F   L  +         L   M + PE    L+ ++    +++ +L   N        K+                    LD++  P + +   + F L  H        ++ ++C  G  +D+   PVT +N   Y+     + + +G++KQF  + +GF+ VFPI+ L MF   EL+ + CG    +QH +W +  LQ       G+   S++ QY  E+L   N+ E++ F+QF++G   LP GG K L P LTIV+K + +        PSV TC++YLKLP+Y ++  ++ KL  A N+  + F+L+
Sbjct: 2410 YVHAVHGLFPLPLGKSSKLPQMTKAKAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIG----LADLMRVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQ------------------LDLDGCPIADL--GLDFVLPGH--------ANIELCRGG--RDT---PVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGSGSEQQHSRWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLPTGGFKALTPPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANEGSMSFHLS 2737

HSP 2 Score: 64.6994 bits (156), Expect = 1.858e-9
Identity = 53/178 (29.78%), Postives = 82/178 (46.07%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSF 6570
            FI   +  K   QL+D   +++ + LP W+ +     PF+F ++ +  +  A  F   R++    QR    +  +  +   + VAP     RL +    I R       IL +AE           +L     SK  LEIQ++ E GTGLGPTLEF  ++S E  R  L +W  +DS+
Sbjct: 2113 FIHPKIMAKANRQLQDPLVIMTGN-LPQWLPQIGMACPFLFPFETRHLLFYATSFDRDRAL----QRLLDTTPDLNAAESSERVAP-----RLDRRKRAISR-----TEILKQAEH----------ILQDFGHSKALLEIQYENEVGTGLGPTLEFYALVSAELQRTDLGLWNGSDSY 2265
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Fly
Match: ctrip (gene:FBgn0260794 transcript:FBtr0303912)

HSP 1 Score: 149.443 bits (376), Expect = 3.881e-35
Identity = 108/365 (29.59%), Postives = 181/365 (49.59%), Query Frame = 1 
Query: 6589 FVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCG----EQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGP-----YPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQ--IGFYLN 7641
            +V + +GLFP P        ++ +   KF+ LG FMAK++ D+R++DLPFS  F   L  +         L   M + PE    L+ ++    +++ +L   N        K+                    LD++  P + +   + F L  H        ++ ++C  G  +D+   PVT +N   Y+     + + +G++KQF  + +GF+ VFPI+ L MF   EL+ + CG    +QH +W +  LQ       G+   S++ QY  E+L   N+ E++ F+QF++G   LP GG K L P LTIV+K + +        PSV TC++YLKLP+Y ++  ++ KL  A N+  + F+L+
Sbjct: 2410 YVHAVHGLFPLPLGKSSKLPQMTKAKAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIG----LADLMRVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQ------------------LDLDGCPIADL--GLDFVLPGH--------ANIELCRGG--RDT---PVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGSGSEQQHSRWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLPTGGFKALTPPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANEGSMSFHLS 2737

HSP 2 Score: 64.6994 bits (156), Expect = 1.858e-9
Identity = 53/178 (29.78%), Postives = 82/178 (46.07%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSF 6570
            FI   +  K   QL+D   +++ + LP W+ +     PF+F ++ +  +  A  F   R++    QR    +  +  +   + VAP     RL +    I R       IL +AE           +L     SK  LEIQ++ E GTGLGPTLEF  ++S E  R  L +W  +DS+
Sbjct: 2113 FIHPKIMAKANRQLQDPLVIMTGN-LPQWLPQIGMACPFLFPFETRHLLFYATSFDRDRAL----QRLLDTTPDLNAAESSERVAP-----RLDRRKRAISR-----TEILKQAEH----------ILQDFGHSKALLEIQYENEVGTGLGPTLEFYALVSAELQRTDLGLWNGSDSY 2265
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Fly
Match: ctrip (gene:FBgn0260794 transcript:FBtr0344029)

HSP 1 Score: 149.443 bits (376), Expect = 3.954e-35
Identity = 108/365 (29.59%), Postives = 181/365 (49.59%), Query Frame = 1 
Query: 6589 FVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCG----EQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGP-----YPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQ--IGFYLN 7641
            +V + +GLFP P        ++ +   KF+ LG FMAK++ D+R++DLPFS  F   L  +         L   M + PE    L+ ++    +++ +L   N        K+                    LD++  P + +   + F L  H        ++ ++C  G  +D+   PVT +N   Y+     + + +G++KQF  + +GF+ VFPI+ L MF   EL+ + CG    +QH +W +  LQ       G+   S++ QY  E+L   N+ E++ F+QF++G   LP GG K L P LTIV+K + +        PSV TC++YLKLP+Y ++  ++ KL  A N+  + F+L+
Sbjct: 2574 YVHAVHGLFPLPLGKSSKLPQMTKAKAKFKFLGKFMAKAVMDSRMLDLPFSLPFYRWLVSEEHSIG----LADLMRVAPEVQNTLVRLQDLVRQREYILSDPNIDAMEKTEKIEQ------------------LDLDGCPIADL--GLDFVLPGH--------ANIELCRGG--RDT---PVTVHNLHQYISLVTYWFLIEGVQKQFEALREGFDSVFPIQRLRMFYPEELECVFCGSGSEQQHSRWEIKMLQESCRTDHGFHQDSQAIQYLYEILASYNRDEQRAFLQFVTGSPRLPTGGFKALTPPLTIVRKTLDENQNPNDYLPSVMTCVNYLKLPDYSSREVMRQKLKVAANEGSMSFHLS 2901

HSP 2 Score: 64.6994 bits (156), Expect = 1.869e-9
Identity = 53/178 (29.78%), Postives = 82/178 (46.07%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSF 6570
            FI   +  K   QL+D   +++ + LP W+ +     PF+F ++ +  +  A  F   R++    QR    +  +  +   + VAP     RL +    I R       IL +AE           +L     SK  LEIQ++ E GTGLGPTLEF  ++S E  R  L +W  +DS+
Sbjct: 2277 FIHPKIMAKANRQLQDPLVIMTGN-LPQWLPQIGMACPFLFPFETRHLLFYATSFDRDRAL----QRLLDTTPDLNAAESSERVAP-----RLDRRKRAISR-----TEILKQAEH----------ILQDFGHSKALLEIQYENEVGTGLGPTLEFYALVSAELQRTDLGLWNGSDSY 2429
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Zebrafish
Match: hectd1 (HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-030616-153])

HSP 1 Score: 295.049 bits (754), Expect = 2.701e-79
Identity = 205/620 (33.06%), Postives = 310/620 (50.00%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLP--------------------------------FSELFLEILCKD---------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDG--LC-----LDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  RPS    RDD   P  F +GRLK    ++PR    G +++  AES          ++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R SL +W+  D F ++E+              +V    GLFP P+P D    E + K F  LGIF+AK +QDNR++DLP                                FSE+  E   ++         F + +K E++                  + F L+ P R LFL  ++    +++++L      GN++L +     +   + +      G  LC     L+ +F P+SK++G                       ++  + +   E VT +NAE Y++   +F M+ GI+KQ     +GFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLTIV+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 1996 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATMERSRPSTTVRRDD---PGEFRVGRLKHERVKVPR----GESMMEWAES----------VMQIHADRKSVLEVEFQGEEGTGLGPTLEFYALVAAEFQRTSLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFPAPFPQDSDELERITKLFLFLGIFLAKCIQDNRLVDLPISQPFFKLLCMGDIKSNMSKLLYQTRGESDCHFSEIQSEASTEEGQDTYSVGSFDEDSKSEFILDPPKPKPPAWYHGILTWEDFELVNPHRALFLKELKALSVKRRQIL------GNKSLSEDEKNTRLQDLMLKNPMGSGPPLCVEDLGLNFQFCPSSKVHG---------------------FSSVDLKPNGEDEMVTMDNAEEYVELMFDFCMHTGIQKQMEAFREGFNKVFPMEKLSSFSHKEVQMILCGNQSPSWTAEDIVNYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTIVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2570

HSP 2 Score: 108.997 bits (271), Expect = 7.595e-23
Identity = 75/239 (31.38%), Postives = 126/239 (52.72%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V+SF+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLSFIRDSGHLVHKDTLHSAMAVVSRLCSKMEPQDSSLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.323e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Zebrafish
Match: hectd1 (HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-030616-153])

HSP 1 Score: 295.049 bits (754), Expect = 3.073e-79
Identity = 205/620 (33.06%), Postives = 310/620 (50.00%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLP--------------------------------FSELFLEILCKD---------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDG--LC-----LDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  RPS    RDD   P  F +GRLK    ++PR    G +++  AES          ++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R SL +W+  D F ++E+              +V    GLFP P+P D    E + K F  LGIF+AK +QDNR++DLP                                FSE+  E   ++         F + +K E++                  + F L+ P R LFL  ++    +++++L      GN++L +     +   + +      G  LC     L+ +F P+SK++G                       ++  + +   E VT +NAE Y++   +F M+ GI+KQ     +GFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLTIV+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2002 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATMERSRPSTTVRRDD---PGEFRVGRLKHERVKVPR----GESMMEWAES----------VMQIHADRKSVLEVEFQGEEGTGLGPTLEFYALVAAEFQRTSLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFPAPFPQDSDELERITKLFLFLGIFLAKCIQDNRLVDLPISQPFFKLLCMGDIKSNMSKLLYQTRGESDCHFSEIQSEASTEEGQDTYSVGSFDEDSKSEFILDPPKPKPPAWYHGILTWEDFELVNPHRALFLKELKALSVKRRQIL------GNKSLSEDEKNTRLQDLMLKNPMGSGPPLCVEDLGLNFQFCPSSKVHG---------------------FSSVDLKPNGEDEMVTMDNAEEYVELMFDFCMHTGIQKQMEAFREGFNKVFPMEKLSSFSHKEVQMILCGNQSPSWTAEDIVNYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTIVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2576

HSP 2 Score: 108.997 bits (271), Expect = 7.599e-23
Identity = 75/239 (31.38%), Postives = 126/239 (52.72%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V+SF+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLSFIRDSGHLVHKDTLHSAMAVVSRLCSKMEPQDSSLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.324e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Zebrafish
Match: hectd1 (HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-030616-153])

HSP 1 Score: 295.049 bits (754), Expect = 3.073e-79
Identity = 205/620 (33.06%), Postives = 310/620 (50.00%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLP--------------------------------FSELFLEILCKD---------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDG--LC-----LDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  RPS    RDD   P  F +GRLK    ++PR    G +++  AES          ++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R SL +W+  D F ++E+              +V    GLFP P+P D    E + K F  LGIF+AK +QDNR++DLP                                FSE+  E   ++         F + +K E++                  + F L+ P R LFL  ++    +++++L      GN++L +     +   + +      G  LC     L+ +F P+SK++G                       ++  + +   E VT +NAE Y++   +F M+ GI+KQ     +GFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLTIV+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2002 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATMERSRPSTTVRRDD---PGEFRVGRLKHERVKVPR----GESMMEWAES----------VMQIHADRKSVLEVEFQGEEGTGLGPTLEFYALVAAEFQRTSLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFPAPFPQDSDELERITKLFLFLGIFLAKCIQDNRLVDLPISQPFFKLLCMGDIKSNMSKLLYQTRGESDCHFSEIQSEASTEEGQDTYSVGSFDEDSKSEFILDPPKPKPPAWYHGILTWEDFELVNPHRALFLKELKALSVKRRQIL------GNKSLSEDEKNTRLQDLMLKNPMGSGPPLCVEDLGLNFQFCPSSKVHG---------------------FSSVDLKPNGEDEMVTMDNAEEYVELMFDFCMHTGIQKQMEAFREGFNKVFPMEKLSSFSHKEVQMILCGNQSPSWTAEDIVNYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTIVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2576

HSP 2 Score: 108.997 bits (271), Expect = 7.599e-23
Identity = 75/239 (31.38%), Postives = 126/239 (52.72%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V+SF+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLSFIRDSGHLVHKDTLHSAMAVVSRLCSKMEPQDSSLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.324e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Zebrafish
Match: hectd1 (HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-030616-153])

HSP 1 Score: 294.664 bits (753), Expect = 3.213e-79
Identity = 205/620 (33.06%), Postives = 310/620 (50.00%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLP--------------------------------FSELFLEILCKD---------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDG--LC-----LDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  RPS    RDD   P  F +GRLK    ++PR    G +++  AES          ++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R SL +W+  D F ++E+              +V    GLFP P+P D    E + K F  LGIF+AK +QDNR++DLP                                FSE+  E   ++         F + +K E++                  + F L+ P R LFL  ++    +++++L      GN++L +     +   + +      G  LC     L+ +F P+SK++G                       ++  + +   E VT +NAE Y++   +F M+ GI+KQ     +GFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLTIV+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 1935 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATMERSRPSTTVRRDD---PGEFRVGRLKHERVKVPR----GESMMEWAES----------VMQIHADRKSVLEVEFQGEEGTGLGPTLEFYALVAAEFQRTSLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFPAPFPQDSDELERITKLFLFLGIFLAKCIQDNRLVDLPISQPFFKLLCMGDIKSNMSKLLYQTRGESDCHFSEIQSEASTEEGQDTYSVGSFDEDSKSEFILDPPKPKPPAWYHGILTWEDFELVNPHRALFLKELKALSVKRRQIL------GNKSLSEDEKNTRLQDLMLKNPMGSGPPLCVEDLGLNFQFCPSSKVHG---------------------FSSVDLKPNGEDEMVTMDNAEEYVELMFDFCMHTGIQKQMEAFREGFNKVFPMEKLSSFSHKEVQMILCGNQSPSWTAEDIVNYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTIVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2509

HSP 2 Score: 108.997 bits (271), Expect = 7.552e-23
Identity = 75/239 (31.38%), Postives = 126/239 (52.72%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V+SF+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLSFIRDSGHLVHKDTLHSAMAVVSRLCSKMEPQDSSLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.319e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Zebrafish
Match: trip12 (thyroid hormone receptor interactor 12 [Source:NCBI gene;Acc:564866])

HSP 1 Score: 191.045 bits (484), Expect = 1.031e-47
Identity = 150/526 (28.52%), Postives = 251/526 (47.72%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFL------EEENEFVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVP-FPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVK-----DGPYPSVNTCMHYLKLP 7569
            FI+  +  K   QL+D   +++ + +P+W+ E  +  PF F +D +  +     F   R+   +Q+    N +  +   +D  VAP   L R K+ I +        + +L +AES       ++DL      S+  LEIQ++ E GTGLGPT EF  ++S+E  R  L +W   +  L      +E  +++FS  GLF  P+        + +   KFR LG  MAK++ D R++DLP    F + + +  S  +  + +     I P     +  +E    +K+++ +      +R+  +   Q    ++ + G + + L LD           T+P FP                  N+  +K     PVT +N E+YL+  + + +N+G+ +QF    +GF  VFP+  L  F   EL QLLCG +   W +  L     P  GY   S++ ++  EVL   +  ++++F+QF++G   LP GG ++L P LTIV+K  +     D   PSV TC++YLKLP
Sbjct: 1564 FINSKLTAKANRQLQDPLVIMTGN-IPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRA---MQRLLDTNPEINQSDSQDSRVAPR--LDRKKRTINR--------DELLKQAES------VMQDL----GSSRAMLEIQYENEVGTGLGPTQEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYMFSSRGLFAVPFGRTTKPAHIAKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHESSISSHDLVN----IDPGVAKSIQHLEDIIRQKKRIEQ------DRSHTRETLQQALESLNMNGCSVEDLGLDF----------TLPGFP------------------NIELKKGGKDVPVTIHNLEDYLRLVVYWTLNEGVLRQFESFREGFESVFPLHHLQYFYPEELDQLLCGSKSESWDVKTLMECCRPDHGYTHDSRAVRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLP 2027
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Xenopus
Match: fbl (fibrillarin [Source:Xenbase;Acc:XB-GENE-970225])

HSP 1 Score: 273.863 bits (699), Expect = 1.046e-72
Identity = 199/616 (32.31%), Postives = 300/616 (48.70%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEKFRL---LGIFMAKSLQDNRIMDLPFSELFLEILCKD--FSDYNKKEYLKR-----------------------------------FMLIYPE-------RGLFL-MSIELFCEEKQKLLKTINE--------AGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDME-------FLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K++ Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF +  L +W+  D F ++E+              +V    GLF  P+P D  +EEL    RL   LG+F+AK +QDNR++DLP S+ F +++C     S+ +K  Y  R                                   F+L  P+       +G+      EL    + + L+ I E         GNR L +     +   + +   +  G  + +E       F P+S++YG   F   D                     +   E VT +NAE Y+    +F M  G++KQ      GFN+VFP++ L  FS  E++ +LCG Q   WS  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 1955 FTSKKITTKIVQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERSRTASAVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQKTDLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFIAPYPQD--SEELDRVTRLCHFLGVFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLLYASRGEESEHCTESQSEASTEDGHDALSVGSFEEDCKSEFILDPPKPKPPAWFQGILTWEDFELINPHRARFLRDIRELAVKRRQILGNRCLSEDEKNTQLQELMLKNPSGSGPPVSIEDLGLNFQFCPSSRVYG---FSAVD------------------LRPNGEDEMVTIDNAEEYVDLMFDFCMQTGVQKQMEAFRSGFNKVFPMEKLGSFSPEEVQMILCGNQSPSWSAEDIINYTEPKLGYTRESPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRDRLLAATMEKGFHLN 2529

HSP 2 Score: 108.612 bits (270), Expect = 1.785e-22
Identity = 74/239 (30.96%), Postives = 127/239 (53.14%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V  +G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVEGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDASLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAQHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.881e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Xenopus
Match: fbl (fibrillarin [Source:Xenbase;Acc:XB-GENE-970225])

HSP 1 Score: 273.478 bits (698), Expect = 1.320e-72
Identity = 199/616 (32.31%), Postives = 300/616 (48.70%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEKFRL---LGIFMAKSLQDNRIMDLPFSELFLEILCKD--FSDYNKKEYLKR-----------------------------------FMLIYPE-------RGLFL-MSIELFCEEKQKLLKTINE--------AGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDME-------FLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K++ Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF +  L +W+  D F ++E+              +V    GLF  P+P D  +EEL    RL   LG+F+AK +QDNR++DLP S+ F +++C     S+ +K  Y  R                                   F+L  P+       +G+      EL    + + L+ I E         GNR L +     +   + +   +  G  + +E       F P+S++YG   F   D                     +   E VT +NAE Y+    +F M  G++KQ      GFN+VFP++ L  FS  E++ +LCG Q   WS  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 1988 FTSKKITTKIVQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERSRTASAVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQKTDLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFIAPYPQD--SEELDRVTRLCHFLGVFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLLYASRGEESEHCTESQSEASTEDGHDALSVGSFEEDCKSEFILDPPKPKPPAWFQGILTWEDFELINPHRARFLRDIRELAVKRRQILGNRCLSEDEKNTQLQELMLKNPSGSGPPVSIEDLGLNFQFCPSSRVYG---FSAVD------------------LRPNGEDEMVTIDNAEEYVDLMFDFCMQTGVQKQMEAFRSGFNKVFPMEKLGSFSPEEVQMILCGNQSPSWSAEDIINYTEPKLGYTRESPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRDRLLAATMEKGFHLN 2562

HSP 2 Score: 108.612 bits (270), Expect = 1.790e-22
Identity = 74/239 (30.96%), Postives = 127/239 (53.14%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V  +G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVEGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDASLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAQHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.885e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Xenopus
Match: fbl (fibrillarin [Source:Xenbase;Acc:XB-GENE-970225])

HSP 1 Score: 273.478 bits (698), Expect = 1.325e-72
Identity = 199/616 (32.31%), Postives = 300/616 (48.70%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEKFRL---LGIFMAKSLQDNRIMDLPFSELFLEILCKD--FSDYNKKEYLKR-----------------------------------FMLIYPE-------RGLFL-MSIELFCEEKQKLLKTINE--------AGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDME-------FLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K++ Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF +  L +W+  D F ++E+              +V    GLF  P+P D  +EEL    RL   LG+F+AK +QDNR++DLP S+ F +++C     S+ +K  Y  R                                   F+L  P+       +G+      EL    + + L+ I E         GNR L +     +   + +   +  G  + +E       F P+S++YG   F   D                     +   E VT +NAE Y+    +F M  G++KQ      GFN+VFP++ L  FS  E++ +LCG Q   WS  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 1896 FTSKKITTKIVQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERSRTASAVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQKTDLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFIAPYPQD--SEELDRVTRLCHFLGVFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLLYASRGEESEHCTESQSEASTEDGHDALSVGSFEEDCKSEFILDPPKPKPPAWFQGILTWEDFELINPHRARFLRDIRELAVKRRQILGNRCLSEDEKNTQLQELMLKNPSGSGPPVSIEDLGLNFQFCPSSRVYG---FSAVD------------------LRPNGEDEMVTIDNAEEYVDLMFDFCMQTGVQKQMEAFRSGFNKVFPMEKLGSFSPEEVQMILCGNQSPSWSAEDIINYTEPKLGYTRESPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRDRLLAATMEKGFHLN 2470

HSP 2 Score: 108.612 bits (270), Expect = 1.775e-22
Identity = 74/239 (30.96%), Postives = 127/239 (53.14%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V  +G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVEGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDASLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAQHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.875e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Xenopus
Match: fbl (fibrillarin [Source:Xenbase;Acc:XB-GENE-970225])

HSP 1 Score: 273.478 bits (698), Expect = 1.329e-72
Identity = 199/616 (32.31%), Postives = 300/616 (48.70%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEKFRL---LGIFMAKSLQDNRIMDLPFSELFLEILCKD--FSDYNKKEYLKR-----------------------------------FMLIYPE-------RGLFL-MSIELFCEEKQKLLKTINE--------AGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDME-------FLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K++ Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF +  L +W+  D F ++E+              +V    GLF  P+P D  +EEL    RL   LG+F+AK +QDNR++DLP S+ F +++C     S+ +K  Y  R                                   F+L  P+       +G+      EL    + + L+ I E         GNR L +     +   + +   +  G  + +E       F P+S++YG   F   D                     +   E VT +NAE Y+    +F M  G++KQ      GFN+VFP++ L  FS  E++ +LCG Q   WS  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2006 FTSKKITTKIVQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERSRTASAVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQKTDLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFIAPYPQD--SEELDRVTRLCHFLGVFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLLYASRGEESEHCTESQSEASTEDGHDALSVGSFEEDCKSEFILDPPKPKPPAWFQGILTWEDFELINPHRARFLRDIRELAVKRRQILGNRCLSEDEKNTQLQELMLKNPSGSGPPVSIEDLGLNFQFCPSSRVYG---FSAVD------------------LRPNGEDEMVTIDNAEEYVDLMFDFCMQTGVQKQMEAFRSGFNKVFPMEKLGSFSPEEVQMILCGNQSPSWSAEDIINYTEPKLGYTRESPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRDRLLAATMEKGFHLN 2580

HSP 2 Score: 108.612 bits (270), Expect = 1.793e-22
Identity = 74/239 (30.96%), Postives = 127/239 (53.14%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V  +G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVEGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDASLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAQHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.886e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Xenopus
Match: fbl (fibrillarin [Source:Xenbase;Acc:XB-GENE-970225])

HSP 1 Score: 273.478 bits (698), Expect = 1.623e-72
Identity = 199/616 (32.31%), Postives = 300/616 (48.70%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEKFRL---LGIFMAKSLQDNRIMDLPFSELFLEILCKD--FSDYNKKEYLKR-----------------------------------FMLIYPE-------RGLFL-MSIELFCEEKQKLLKTINE--------AGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDME-------FLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K++ Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF +  L +W+  D F ++E+              +V    GLF  P+P D  +EEL    RL   LG+F+AK +QDNR++DLP S+ F +++C     S+ +K  Y  R                                   F+L  P+       +G+      EL    + + L+ I E         GNR L +     +   + +   +  G  + +E       F P+S++YG   F   D                     +   E VT +NAE Y+    +F M  G++KQ      GFN+VFP++ L  FS  E++ +LCG Q   WS  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 1957 FTSKKITTKIVQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERSRTASAVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQKTDLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFIAPYPQD--SEELDRVTRLCHFLGVFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLLYASRGEESEHCTESQSEASTEDGHDALSVGSFEEDCKSEFILDPPKPKPPAWFQGILTWEDFELINPHRARFLRDIRELAVKRRQILGNRCLSEDEKNTQLQELMLKNPSGSGPPVSIEDLGLNFQFCPSSRVYG---FSAVD------------------LRPNGEDEMVTIDNAEEYVDLMFDFCMQTGVQKQMEAFRSGFNKVFPMEKLGSFSPEEVQMILCGNQSPSWSAEDIINYTEPKLGYTRESPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRDRLLAATMEKGFHLN 2531

HSP 2 Score: 108.612 bits (270), Expect = 1.785e-22
Identity = 74/239 (30.96%), Postives = 127/239 (53.14%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V  +G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVEGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDASLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAQHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.882e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Mouse
Match: Hectd1 (HECT domain E3 ubiquitin protein ligase 1 [Source:MGI Symbol;Acc:MGI:2384768])

HSP 1 Score: 287.73 bits (735), Expect = 4.958e-77
Identity = 202/620 (32.58%), Postives = 306/620 (49.35%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLPFSELFLEIL-----------------------CKD------------------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDG-------LCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R  L  W+  D+F ++E+              +V    GLF  P+P D    E + K F  LGIF+AK +QDNR++DLP S+ F +++                       C +                  F + +K E++                  + F L+ P R  FL  I+    +++++L      GN++L +     K   + +   +  G       L L+ +F P+S+IYG     L           S +D            E +T +NAE Y+    +F M+ GI+KQ     DGFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2036 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGTWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQIL------GNKSLSEDEKNTKLQELVLRNPSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDL---------KPSGED------------EMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2610

HSP 2 Score: 107.071 bits (266), Expect = 3.922e-22
Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPS*FCTENASTS 892
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL       +M         PS  C    ST+
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELLS------RMAAAGGTVSGPSSACKPGRSTT 261

HSP 3 Score: 72.0182 bits (175), Expect = 1.431e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Mouse
Match: Hectd1 (HECT domain E3 ubiquitin protein ligase 1 [Source:MGI Symbol;Acc:MGI:2384768])

HSP 1 Score: 286.189 bits (731), Expect = 1.747e-76
Identity = 203/623 (32.58%), Postives = 308/623 (49.44%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLPFSELFLEIL-----------------------CKD------------------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDG-------LCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQ---FAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R  L  W+  D+F ++E+              +V    GLF  P+P D    E + K F  LGIF+AK +QDNR++DLP S+ F +++                       C +                  F + +K E++                  + F L+ P R  FL  I+    +++++L      GN++L +     K   + +   +  G       L L+ +F P+S+IYG     L           S +D            E +T +NAE Y+    +F M+ GI+KQ   F   +DGFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2041 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGTWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQIL------GNKSLSEDEKNTKLQELVLRNPSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDL---------KPSGED------------EMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRGNVDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2618

HSP 2 Score: 107.071 bits (266), Expect = 3.924e-22
Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPS*FCTENASTS 892
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL       +M         PS  C    ST+
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELLS------RMAAAGGTVSGPSSACKPGRSTT 261

HSP 3 Score: 68.5514 bits (166), Expect = 1.851e-10
Identity = 38/88 (43.18%), Postives = 48/88 (54.55%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELL-LSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + +     F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 450
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Mouse
Match: Trip12 (thyroid hormone receptor interactor 12 [Source:MGI Symbol;Acc:MGI:1309481])

HSP 1 Score: 187.963 bits (476), Expect = 8.063e-48
Identity = 149/526 (28.33%), Postives = 245/526 (46.58%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFL------EEENEFVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVP-FPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVK-----DGPYPSVNTCMHYLKLP 7569
            FI+  +  K   QL+D   +++ + +P+W+ E  +  PF F +D +  +     F   R+   +Q+    N +  +   +D  VAP     RL +    + R       +L +AES       ++DL      S+  LEIQ++ E GTGLGPTLEF  ++S+E  R  L +W   +  L      +E  +++ +  GLF  P+        + +   KFR LG  MAK++ D R++DLP    F + + +  +     +       I P     +  +E    +K++L +      +++  K   Q     + + G + + L LD           T+P FP                  N+  +K     PVT +N E YL+  + +A+N+G+ +QF    DGF  VFP+  L  F   EL QLLCG +   W    L     P  GY   S++ ++  E+L   +  ++++F+QF++G   LP GG ++L P LTIV+K  +     D   PSV TC++YLKLP
Sbjct:  341 FINSKLTAKANRQLQDPLVIMTGN-IPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRA---MQRLLDTNPEINQSDSQDSRVAP-----RLDRKKRTVNR-----EELLKQAES------VMQDL----GSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLCLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFD----IDPVVARSVYHLEDIVRQKKRLEQ------DKSQTKESLQYALETLTMNGCSVEDLGLDF----------TLPGFP------------------NIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLCHLQYFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLP 804
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Mouse
Match: Trip12 (thyroid hormone receptor interactor 12 [Source:MGI Symbol;Acc:MGI:1309481])

HSP 1 Score: 184.882 bits (468), Expect = 8.157e-46
Identity = 149/526 (28.33%), Postives = 245/526 (46.58%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFL------EEENEFVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVP-FPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVK-----DGPYPSVNTCMHYLKLP 7569
            FI+  +  K   QL+D   +++ + +P+W+ E  +  PF F +D +  +     F   R+   +Q+    N +  +   +D  VAP     RL +    + R       +L +AES       ++DL      S+  LEIQ++ E GTGLGPTLEF  ++S+E  R  L +W   +  L      +E  +++ +  GLF  P+        + +   KFR LG  MAK++ D R++DLP    F + + +  +     +       I P     +  +E    +K++L +      +++  K   Q     + + G + + L LD           T+P FP                  N+  +K     PVT +N E YL+  + +A+N+G+ +QF    DGF  VFP+  L  F   EL QLLCG +   W    L     P  GY   S++ ++  E+L   +  ++++F+QF++G   LP GG ++L P LTIV+K  +     D   PSV TC++YLKLP
Sbjct: 1536 FINSKLTAKANRQLQDPLVIMTGN-IPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRA---MQRLLDTNPEINQSDSQDSRVAP-----RLDRKKRTVNR-----EELLKQAES------VMQDL----GSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLCLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFD----IDPVVARSVYHLEDIVRQKKRLEQ------DKSQTKESLQYALETLTMNGCSVEDLGLDF----------TLPGFP------------------NIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLCHLQYFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLP 1999
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Mouse
Match: Trip12 (thyroid hormone receptor interactor 12 [Source:MGI Symbol;Acc:MGI:1309481])

HSP 1 Score: 184.882 bits (468), Expect = 8.157e-46
Identity = 149/526 (28.33%), Postives = 245/526 (46.58%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFL------EEENEFVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVP-FPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVK-----DGPYPSVNTCMHYLKLP 7569
            FI+  +  K   QL+D   +++ + +P+W+ E  +  PF F +D +  +     F   R+   +Q+    N +  +   +D  VAP     RL +    + R       +L +AES       ++DL      S+  LEIQ++ E GTGLGPTLEF  ++S+E  R  L +W   +  L      +E  +++ +  GLF  P+        + +   KFR LG  MAK++ D R++DLP    F + + +  +     +       I P     +  +E    +K++L +      +++  K   Q     + + G + + L LD           T+P FP                  N+  +K     PVT +N E YL+  + +A+N+G+ +QF    DGF  VFP+  L  F   EL QLLCG +   W    L     P  GY   S++ ++  E+L   +  ++++F+QF++G   LP GG ++L P LTIV+K  +     D   PSV TC++YLKLP
Sbjct: 1536 FINSKLTAKANRQLQDPLVIMTGN-IPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRA---MQRLLDTNPEINQSDSQDSRVAP-----RLDRKKRTVNR-----EELLKQAES------VMQDL----GSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLCLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFD----IDPVVARSVYHLEDIVRQKKRLEQ------DKSQTKESLQYALETLTMNGCSVEDLGLDF----------TLPGFP------------------NIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLCHLQYFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLP 1999
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. UniProt/SwissProt
Match: sp|V6CLA2|HECD1_CAEEL (E3 ubiquitin-protein ligase hecd-1 OS=Caenorhabditis elegans OX=6239 GN=hecd-1 PE=1 SV=1)

HSP 1 Score: 292.352 bits (747), Expect = 1.664e-77
Identity = 203/571 (35.55%), Postives = 290/571 (50.79%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFR--DDLVAPFH------FLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTD-----SFLEEENE------------FVFSKNGLFPYPWP-ADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCK-DFSDYNKKEYLKR------FMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTT--FDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            FIS  +  KV   L D   + +R +LP W      KYP +F  + +   ++A  FGVSR+++WLQQR     +  R S +  +   A  H       +GRL+    ++ R               ++   A+R L+ FHA  K  LEI++  EEGTGLGPTLEF  +++ E  R SL +WV  D     S   EE E            +V    GLFP P P     T+   + FR+LG+F+AK L D R++DLP S  FL++L      D  +   L +      F  + P +G FL  +    + K+ +    +   N    K+ +    L + I G+T   + L L+    P SK++      L D                 G + D     VT +N E Y+++   F +N GI  Q     DGF+ VFP+++L  +S  E+++LL GEQ  +WS  ++ NYTEP  GY   S  +  F++V+  L   ERK F+QF +GCSSLPPGGL NL PRLTIV+K    DG YPSVNTC+HYLKLPEY + + L+ +LL A N+ GF+LN
Sbjct: 2117 FISDKLTLKVTQVLSDALVVAAR-SLPEWCSRLVYKYPCLFTVETRNMYMQATAFGVSRTIVWLQQRRDAAVERARGSAQAGNSSAARQHDRYHEYRVGRLRHERVKVTRA------------EETLLDQAIR-LMKFHADRKAVLEIEYTNEEGTGLGPTLEFYALVAAELQRKSLALWVCDDDDTHASKSGEEREVDLGEGKKPIGYYVRRVGGLFPAPLPPGTDETKRAADMFRVLGVFLAKVLLDGRLVDLPLSRPFLKLLVHPQIGDDARGPNLHKILSLDDFEEVNPVKGSFLKELRALAQRKRLIENDTSIDSNSKRRKIAE----LKLHIKGSTCRVEDLALNFTVNPPSKVFQYAEMELVDG----------------GSDID-----VTIDNVEQYVEKCEEFYLNTGIAYQMRAFRDGFDRVFPLRTLRAYSPEEVQRLLSGEQCPEWSRDDILNYTEPKLGYTRESPGFLRFVDVMEALTAQERKNFLQFATGCSSLPPGGLANLHPRLTIVRKVESGDGSYPSVNTCVHYLKLPEYSSSAILRERLLTAINEKGFHLN 2648

HSP 2 Score: 103.605 bits (257), Expect = 2.678e-20
Identity = 73/258 (28.29%), Postives = 137/258 (53.10%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSG---SEEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIE-KIIDDLLEMTMVQLKMDNQTSHNQN 856
            MD ++ P  LL WLQ+G     ++QL ALEQLC+ LL  ++ +   +  PP T+IP L  +  D      +LE   R +TYY+  + +E   R+    G++ AIC RL   ++++    DL +Q +KLLE +C+R+T ++ + GG + +++ +      +H DT+ S   ++ ++  K++P+D  L +  E L    +H D K+ E +L C  ++      K +    L +   +++ L+ + +     ++ T+ + N
Sbjct:    1 MDGID-PETLLEWLQTGIGDERDLQLMALEQLCMLLLMADNIDRCFESCPPRTFIPALCKIFIDETAPDNVLEVTARAITYYLD-VSNECTRRITQVDGAVKAICTRLAAADISDRSSKDLAEQCVKLLEHVCQRETMAVYDAGGINAMLTLVRVHGTQVHKDTMHSAMSVVTRLCGKMEPTDPELGKCAESLGALLEHEDPKVSESALRCFAALTDRFVRKMMDPAELAMHSNLVEHLISIMVASNDENSPTTASAN 256

HSP 3 Score: 68.1662 bits (165), Expect = 1.341e-9
Identity = 45/140 (32.14%), Postives = 71/140 (50.71%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINNQTMDFYVKDVEGITVTERLEQFIKLNSN--PNKIEEINDFILKIENQKLNVKT 1871
            H  L+ AI   ++  L + + S   D NF D  GQ+  NWASA G +E V  L  +G D N G + +SLHYAA  G   V+K L+  +  +  ++D +G T  ++  +    + N   N +E  + F+   E+ K+   T
Sbjct:  342 HRQLIDAIRQKDLTALVDAIESGQVDVNFADDVGQSLTNWASAFGSIEMVQYLCDKGSDVNKGHKSSSLHYAACFGRPDVVKLLL-QRGANPDLRDEDGKTALDKARERSDDDHNQVANILESPSAFMRNKEDPKVKAST 480
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. UniProt/SwissProt
Match: sp|Q69ZR2|HECD1_MOUSE (E3 ubiquitin-protein ligase HECTD1 OS=Mus musculus OX=10090 GN=Hectd1 PE=1 SV=2)

HSP 1 Score: 286.189 bits (731), Expect = 1.222e-75
Identity = 203/623 (32.58%), Postives = 308/623 (49.44%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLPFSELFLEIL-----------------------CKD------------------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDG-------LCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQ---FAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R  L  W+  D+F ++E+              +V    GLF  P+P D    E + K F  LGIF+AK +QDNR++DLP S+ F +++                       C +                  F + +K E++                  + F L+ P R  FL  I+    +++++L      GN++L +     K   + +   +  G       L L+ +F P+S+IYG     L           S +D            E +T +NAE Y+    +F M+ GI+KQ   F   +DGFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2041 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGTWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQIL------GNKSLSEDEKNTKLQELVLRNPSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDL---------KPSGED------------EMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRGNVDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2618

HSP 2 Score: 107.071 bits (266), Expect = 2.745e-21
Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPS*FCTENASTS 892
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL       +M         PS  C    ST+
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELLS------RMAAAGGTVSGPSSACKPGRSTT 261

HSP 3 Score: 68.5514 bits (166), Expect = 1.295e-9
Identity = 38/88 (43.18%), Postives = 48/88 (54.55%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELL-LSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + +     F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 450
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. UniProt/SwissProt
Match: sp|Q9ULT8|HECD1_HUMAN (E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3)

HSP 1 Score: 284.263 bits (726), Expect = 4.032e-75
Identity = 200/614 (32.57%), Postives = 305/614 (49.67%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLPFSELFLEIL-----------------------CKD------------------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHD-QLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  R +    RDD   P  F +GRLK    ++PR    G +++  AE          +++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R  L  W+  D+F ++E+              +V    GLF  P+P D    E + K F  LGIF+AK +QDNR++DLP S+ F +++                       C +                  F + +K E++                  + F L+ P R  FL  I+    +++++L     + +    K+ +  LK  +      + + L L+ +F P+S+IYG     L           S +D            E +T +NAE Y+    +F M+ GI+KQ     DGFN+VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLT+V+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2036 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDD---PGEFRVGRLKHERVKVPR----GESLMEWAE----------NVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDLGAWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEASTEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIKDLAIKRRQILSNKGLSEDEKNTKLQELVLKNPSGSGPPLSIEDLGLNFQFCPSSRIYGFTAVDL---------KPSGED------------EMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2610

HSP 2 Score: 107.071 bits (266), Expect = 2.743e-21
Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPS*FCTENASTS 892
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V++F+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL       +M         PS  C    ST+
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELLS------RMAAAGGTVSGPSSACKPGRSTT 261

HSP 3 Score: 72.0182 bits (175), Expect = 1.001e-10
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. UniProt/SwissProt
Match: sp|Q9VL06|UFD4_DROME (E3 ubiquitin-protein ligase Ufd4 OS=Drosophila melanogaster OX=7227 GN=Ufd4 PE=2 SV=1)

HSP 1 Score: 269.24 bits (687), Expect = 1.462e-70
Identity = 211/705 (29.93%), Postives = 321/705 (45.53%), Query Frame = 1 
Query: 5761 IDNVSEIWHSQFTLFYGFCDKKGPGTSCQNC--FYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVD----------WLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFH-----FLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFS---------------KNGLFPYPWPAD-KLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKD------------------------------------FSDYNKKEY------LKRFMLIYPERGLFLMSIELFCEEKQKLL--KTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            +D   +IW   +T+ Y     +   ++C     F Q    S+++      P + +   F++  +  CS    +E    Q+  L   ++D            +  FIS+ +  K+  Q++D   L S + LP+W     Q  PF+F ++ +        FG SRS++ LQ +     D      R  +++P        +GRLK    ++PR                + W+    ++  H   K  LE++F  EEGTGLGPTLEF  +++ E  R  L MW+  D   E+      S               ++G+FP P P + ++ E +L+ F   G+F+AK LQD R++D+P S  FL++LC +                                     +D NK         L+    I P R  FL  ++     KQ +    TI+      L    ++LK         + + L L   +LP+S IYG     L                       +     VT +N E Y +  +NF +  GI +Q     DGFNEVFP+K L+ F+ SE + ++CGEQ   WS  ++ +YTEP  GY   S  +Q F+ VLL ++  ERK F+QF +GCSSLPPGGL NL PRLT+V+K +   G YPSVNTC+HYLKLP+Y T+  +K +LL A  + GF+LN
Sbjct: 2067 LDKFRKIWEPTYTIVYREVSPEAQESTCLESEEFPQTPDVSSKSGASTLSPNSPMHIGFNVADNNLCSVDDVLELL-TQINGLNQSEIDSDVKEHGVSVLSEDLFISKKITNKLQQQIQDPLVLAS-NALPNWCENLNQSCPFLFPFETRQLYFNCTSFGASRSIVCLQSQ----RDVTVERQRIPIMSPRRDDHEFRIGRLKHERVKVPRNEDL------------LMWAM--QVMKTHCNRKSVLEVEFLDEEGTGLGPTLEFYALVAAEIQRSDLCMWLCDDDLGEDTENSTQSAEGNSKPVGYYVNRREHGIFPAPLPQNSEICENVLKYFWFFGVFVAKVLQDMRLVDIPLSTSFLQLLCHNKVLSRNLQKVISDRRNGDLSVVSEDSDIVETCTKLLRTDSNKSNAFGGILSLENLKEIDPTRYQFLQEMQNLLLRKQSIEFDDTISAEKKHELI---NELKLQTQNGLEVSLEDLALTFTYLPSSSIYGYTQAELL---------------------PNGSSVNVTIDNLEAYCELLMNFILQDGIAQQMKAFSDGFNEVFPLKKLAAFTPSEARMMICGEQFPHWSREDIISYTEPKLGYNKDSPGFQRFVNVLLSMSGDERKAFLQFTTGCSSLPPGGLANLHPRLTVVRKVDAGVGSYPSVNTCVHYLKLPDYPTEEIMKERLLTATKEKGFHLN 2727

HSP 2 Score: 90.5077 bits (223), Expect = 2.495e-16
Identity = 68/215 (31.63%), Postives = 114/215 (53.02%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSI 730
            M DV+ P  LL WL  G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V+  G++ AIC  L   ++++    DL +Q IK+LE +C R+  ++   GG + V+SF+      +H DT+ S   ++ ++  K++P+   +    E LS   +H D  + + +L C  S+
Sbjct:    1 MGDVD-PETLLEWLSMGQGDERDMQLIALEQLCMLLLMSDNVDRCFESCPPRTFLPALCKIFLDELAPENVLEVTARAITYYLD-VSAECTRRIVSIDGAIKAICNHLVVADLSSRTSRDLAEQCIKVLELICTREAGAVFEGGGLNCVLSFIRDCGSQVHKDTLHSAMSVVSRLCTKVEPNTPCIQNCVESLSTLLQHEDPMVSDGALKCFASV 213

HSP 3 Score: 75.0998 bits (183), Expect = 1.225e-11
Identity = 56/183 (30.60%), Postives = 86/183 (46.99%), Query Frame = 3 
Query: 1167 VIIDLILCIIRGSHQFLHNLLVKSKLVDIILEITWQYDSSSISILQLIEGM-FDQIMERTTYKSNENIQRYKLSTALGMRVIHNRMYSEEMIQQYWNYHEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALI 1712
              I L+  + RGS    H++L +S+L D  LE   Q D   +     ++ M F  ++    ++  + + R   +   G      R  +    +     H  L+  I + + + L+E + S   D N  D  GQT LNWASA G LE V  L  +G D N G+R +SLHYAA  G  ++ K L+
Sbjct:  303 TTISLLSTLCRGSPSITHDIL-RSQLADA-LERALQGDERCV-----LDCMRFADLLLLLLFEGRQALNRGSNNPNQGQLAPRPRRNNTNTDR----THRQLIDCIRSKDSEALREAIESGGIDVNCMDDVGQTLLNWASAFGTLEMVEYLCEKGADVNKGQRSSSLHYAACFGRPAIAKILL 474
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. UniProt/SwissProt
Match: sp|Q9LYZ7|UPL4_ARATH (E3 ubiquitin-protein ligase UPL4 OS=Arabidopsis thaliana OX=3702 GN=UPL4 PE=3 SV=1)

HSP 1 Score: 217.624 bits (553), Expect = 4.360e-55
Identity = 152/519 (29.29%), Postives = 254/519 (48.94%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLE----EENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLE-ILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGP---YPSVNTCMHYLKLP 7569
            F+S  + +K+  QL D ++ +S   LP W  +     P +F ++ K    +   FG         Q+ + +   +  S         +  G  +     +PR  +        A   +I  SA + ++  +   K  +E+++ +E GTGLGPTLEF  ++S+ F  P L MW +  SF+     E +  + S +GLFP PW     T ++L+KF LLG  +AK+LQD R++DLP S+ F + IL ++ S ++          + PE    L+ ++     K+   +   ++G           KC  +   GT  + LCL+   LP    Y   P+             S +D+ N+             +N E Y++  +N  +  GI+KQ      GFN+VF I+ L +F+  EL+ +LCGE  + +S+ E+ ++ +   GY S+S   +Y L++L E ++ +++ F+QF++G   LP GGL +L P+LTIV+K+  D      PSV TC +YLKLP
Sbjct: 1029 FVSSKLTEKLEQQLRDSFA-VSTCGLPPWFNDLMDSCPCLFSFEAKSKYFRLAAFG--------SQKIRHHPQHLSSS---------NVHGEARPVTGSLPRKKFL-------ACRENILESAAK-MMELYGNQKVVIEVEYSEEVGTGLGPTLEFYTLVSRAFQNPDLGMWRNDCSFIVGKPVEHSGVLASSSGLFPRPWSGTSTTSDVLQKFVLLGTVVAKALQDGRVLDLPLSKAFYKLILGQELSSFD-------IHFVDPELCKTLVELQALVRRKKLFAEAHGDSG---------AAKC-DLSFHGTKIEDLCLEFA-LPGYTDYDLAPY-------------SANDMVNL-------------DNLEEYIKGIVNATVCNGIQKQVEAFRSGFNQVFSIEHLRIFNEEELETMLCGECDL-FSMNEVLDHIKFDHGYTSSSPPVEYLLQILHEFDREQQRAFLQFVTGSPRLPHGGLASLSPKLTIVRKHGSDSSDTDLPSVMTCANYLKLP 1476
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. TrEMBL
Match: A0A0G2YFJ9 (Uncharacterized protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 533.872 bits (1374), Expect = 4.934e-170
Identity = 257/261 (98.47%), Postives = 258/261 (98.85%), Query Frame = 1 
Query: 5347 ISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIV 6129
            + IEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQY  VDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIV
Sbjct:    2 LEIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYXXVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIV 262
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. TrEMBL
Match: G4VA25 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 GN=Smp_169180 PE=4 SV=1)

HSP 1 Score: 342.043 bits (876), Expect = 3.964e-90
Identity = 230/602 (38.21%), Postives = 313/602 (51.99%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPS-----FRDDLVAPFH-----FLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWV------------HTDSFL------------------------------EEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKE---YLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTEN-----------NAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKD-GPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S  +  K+L Q+ D  +L S   LP+W +   Q++  +F ++V+  +  A  FG +R+  WLQ R      ++  S           A  H      +GRL K   +IP                  FW     L+  HA  K ELEIQF  EEGTGLGPTLEF ++L+ E  R   LMWV            H+ S L                              +E N +V +  GLFP PWP D++ E +L +F +LGI +AK LQDNR +DLP S   L++L    S  N       L  F +IYPER  FL  I  F   K  +       GN     ++D    LA+EIFG     LCL MEFLP+SK++G   +PL D Y WE    +     N   E +S H+ VTEN           N E YL+ TL F ++KGI+KQ     DGF  V P++ L++F+++EL +L+ G+  + W+  +L  YT P+ G+   S +YQ  + VL   N  ER+ F+QF +GCSSLPPGGLKNL PRL IV+K + + GPYPSVNTC+HYLKLPEY+++ EL+ +LL+A  +IGFYLN
Sbjct: 2572 FTSTRLTNKLLCQIHDPLALAS-GALPNWCLSLSQRFNILFSFNVRSQLFSACAFGPARAATWLQNRPLQKRTYLSHSDGYSRAGSAGSASGHDRSTSQIGRLHKEFVRIPHNL--------------TFWHWASRLMEEHASRKSELEIQFIGEEGTGLGPTLEFYSLLAAELRRRDGLMWVTNDFTMTTEQSSHSHSVLPTVSSSATIEQHVISNSGQPNSMDNEIDDIDEANIYVNTPYGLFPAPWPGDQVPESVLYRFFILGITVAKCLQDNRRIDLPLSSPLLKLLSTYGSVVNTHNCLLNLNDFCIIYPERAQFLKQITEFHRRKSTM-----SNGNTNEKCIND----LAVEIFGCDLTDLCLSMEFLPSSKLFGFSSYPLKDVYDWEATITTTPRTTNNSTE-ESLHKNVTENSQSIVAPVTVHNIEKYLELTLAFCLDKGIRKQLDAFKDGFERVLPLRWLALFTATELGELIAGDSVVHWTREDLLAYTVPSLGFTKQSPTYQMLINVLCNFNSTERRAFLQFTTGCSSLPPGGLKNLHPRLRIVRKEITNSGPYPSVNTCVHYLKLPEYQSEKELRTRLLQATKEIGFYLN 3148

HSP 2 Score: 99.7525 bits (247), Expect = 1.264e-16
Identity = 67/255 (26.27%), Postives = 125/255 (49.02%), Query Frame = 2 
Query:  113 PYILLNWLQSGSEEMXXXXXXXXXX--XXXXYESN-ETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQ--LKMDNQTSHNQNPS 862
            P I+L WL S ++E++   L  L      + +  N +   + YPP  +IP L  +  D      +LEA  R +TYY+  +  +   R+  +   L A+  RL+  +MT+   ++L QQIIK+L+ +C R+  ++   GG + V+ ++     ++H D +++G  I+ ++  + DP+D  L  W + LS+     +  + + +L    ++V            L    IID LL+   V   ++ DN+ + +  PS
Sbjct:    5 PAIVLEWLDSVNDELRELQLTALEQLCNEVLFSDNVDVFFERYPPRLFIPALCKIFLDELAPDSVLEANARALTYYLD-VSLDCAPRIARSPNVLTAMTSRLDAVDMTSAKSNELGQQIIKMLQLICTREPGAVYTAGGLTSVLRYIRLYPHLLHADVLQAGMDIIRRLFSRADPADKNLTSWIDALSSLLDRRETGVADQALRAFANLVARFTRTGADPSPLADSHIIDCLLQRLRVAGGVETDNEVTDSSGPS 258

HSP 3 Score: 71.633 bits (174), Expect = 4.103e-8
Identity = 44/117 (37.61%), Postives = 61/117 (52.14%), Query Frame = 3 
Query: 1440 QQYWN---YHEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINNQTMDFYVKDVEGITVTERLEQ 1781
            Q  W     H H ++AI   ++D +K  L S   D N+ D  GQT LNWA++ G    V LL T G + NLG R T L YAA+ G + + K L+ N   D   +DV+G    +R  +
Sbjct:  372 QHSWEGDAVHRHFIEAIKRQDLDFMKRSLKSGKIDVNYMDHLGQTLLNWAASFGSPAMVELLCTHGANVNLGVR-TPLDYAASFGRVEICKTLL-NWGADINKQDVQGRKPIDRARE 486
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. TrEMBL
Match: A0A5K3EG17 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 306.22 bits (783), Expect = 4.062e-84
Identity = 200/506 (39.53%), Postives = 265/506 (52.37%), Query Frame = 1 
Query: 6304 LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEE--------------ENEFVFS----------------------------------------KNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILC--KDFSDYNKKEYLKRFMLIYPERG-LFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQH--IKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKD-GPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            LGRL++ +A++PRP            S+S FW+  RD L+ HA  K+ELE+ F  EEGTGLGPT+EF  +LS EFMR    +WV   S  EE              ENE  F                                         KNGLFP  WPA+++     EKFRLLGI +AK LQD R MDLP S  FL +L   +   ++++   L+ F  IYPE+G  FL  +E              E  N +     D+ + L ++ F    + LCL MEF   +  +G   F L D Y WE          N+     +  + V   N E Y++R+++FAMNKGIK+Q     DGFN VFPI++LS+F+ +EL +L+ GE      W   EL +  EP  GY+  S  +   L VL +    ERK FV+F++G  +LPPGG +NL PRL + KK+ +  GPYPSVNTCMHYLKLPEYE++ +LK KLL A NQ GFYLN
Sbjct:  305 LGRLQREVAKVPRP-------TASTSSKSAFWTTTRDFLIAHASRKQELEVGFIDEEGTGLGPTMEFYALLSAEFMRSCHGLWVADYSQREETISKLKEPEIDVVSENETPFDDPEEAVGRCETSCFLDETSVTDRRDGLPHHRSGDATYLSPKNGLFPSAWPANEMPNGTEEKFRLLGIALAKCLQDQRRMDLPLSFSFLRLLTSREKVCEHDRIPRLRSFREIYPEKGDFFLRCLEYL------------EIANSSALSPKDRQE-LEVKTFSARLEDLCLTMEFPAVTTSFGHTSFRLDDSYDWETPEPPILPKANV-----TDGQIVNFENLELYIRRSVDFAMNKGIKRQLEAFTDGFNSVFPIETLSIFTPNELDRLIMGEDTSLSPWKFDELLDAFEPVAGYVRQSLGFHMLLHVLSKFTGSERKAFVRFVTGSPNLPPGGFRNLYPRLKVAKKDARLFGPYPSVNTCMHYLKLPEYESEEQLKEKLLAATNQSGFYLN 785
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. TrEMBL
Match: A0A553QVV2 (Uncharacterized protein OS=Danionella translucida OX=623744 GN=DNTS_027326 PE=4 SV=1)

HSP 1 Score: 309.686 bits (792), Expect = 3.954e-80
Identity = 249/841 (29.61%), Postives = 384/841 (45.66%), Query Frame = 1 
Query: 5515 DQFRLKFQIQKLLPA-----NRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILK-------SDSTFPIANYVLKMLPSPDPILN------IYPIDNVSEIWHSQFTLFY---------------GFCD--------KKGPGTSCQNC-FYQKIKTSNEATDKNKKPANEIDKIFSILHHL-----KCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLPFSELFLEILCK-----------------------------------------DFSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEI---FGT----TFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            D F LK Q   L+PA      R+   Q+  D +        S++Q E   T       +LK        +   P+ NY   +      +L       I P D +  IW   +T+ Y                FC+          G  T+ Q+C      +   +A   + + A  ++ +  +L  L     + S  R +++    V +LQ+   +     F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  RPS    RDD   P  F +GRLK    ++PR    G +++  AES          ++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R SL +W+  D F ++E+              +V    GLFP P+P D    + + K F  LG+F+AK +QDNR++DLP S+   ++LC                                           F +  K E++                  + F L+ P R LFL  ++    +++++L      GN++L +     +  A+ +    G+    + + L L+ +F P+SK++G   F   D     DD                  E VT  NAE Y++   +F M+ GI+KQ     +GFN VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLTIV+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 3694 DDFVLKRQFSALVPAFDPRPGRT-NVQQTTDLEIPQPGTPRSEVQEEVECTPSPRLALVLKVAGLGTTREVELPLNNYKSTIFFYVQKLLQLSCNGAIKP-DKLRRIWEPTYTIMYRELKDSDKERESGKMDFCEHGCRSSGLSSGTLTATQSCDILSAAREQAQAKAGSGQSACSVEDVLQLLRILFTIGGEPSSSRTLQE---DVEELQF---NASPEEFTSKKITTKILQQIEEPLALAS-GALPEWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATMERSRPSTTIRRDD---PGEFRVGRLKHERVKVPR----GESMMEWAES----------VMQIHADRKSVLEVEFQGEEGTGLGPTLEFYALVAAEFQRTSLGIWLCDDDFPDDESRQVDLGGGLKPPGFYVQRSCGLFPAPFPQDSDELDRITKLFLFLGVFLAKCIQDNRLVDLPISQPLFKLLCMGDIKSNMSKLLYRTRIESDGHFSEIQSEASTEEGQDTYSVGSFDEDTKSEFILDPPKPKPPAWYHGILTWEDFDLVNPHRALFLKELKALSVKRRQIL------GNKSLSEDEKNTRLQALMLKNPMGSGPPLSVEDLGLNFQFCPSSKVHG---FSTVDLKPNGDD------------------EMVTMENAEEYVELMFDFCMHTGIQKQMEAFREGFNRVFPMEKLSSFSHKEVQMILCGNQSPSWTAEDIVNYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTIVRKVDATDSSYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 4481

HSP 2 Score: 90.5077 bits (223), Expect = 7.948e-14
Identity = 63/186 (33.87%), Postives = 103/186 (55.38%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRL 643
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V+SF+  +  ++H DT+ S   ++ ++  K++P D  L
Sbjct: 2001 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLSFIRDSGHLVHKDTLHSAMAVVSRLCSKMEPQDSSL 2184

HSP 3 Score: 72.0182 bits (175), Expect = 3.129e-8
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct: 2349 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 2435
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. TrEMBL
Match: A0A4U5MLD9 (Uncharacterized protein OS=Steinernema carpocapsae OX=34508 GN=L596_022299 PE=4 SV=1)

HSP 1 Score: 308.145 bits (788), Expect = 5.895e-80
Identity = 209/566 (36.93%), Postives = 291/566 (51.41%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQR----------AKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTD-----------SFLEEENEFVFSKNGLFPYPWPAD-KLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFM------LIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSK--IYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F+S  + +K++ +L D   L+S + LP W       YPF+F  + +   L+A  FG SR+++WLQ R             +   I    RDD  A F  +GR+K    ++PR     + +L E        +AVR +L FHA  K  LEIQ+  EEGTGLGPTLEF  +++ EF R SL MW   D             ++    +V    GLFP P PA+ K ++   E F LLGIF+AK LQD R++DLP S  FL++L            L   +      +IYP +  FL  ++ F +  + + +   E  ++     H   +C          D LCL     P SK   YG+V                  D+   G E       V  +N   YL   L F +N GI+ Q     +GF+ VFP+ SL  F+S+EL+ LL GEQ  +W+  +L  YTEP  GY   S  +  F++VL+++   ERK F+QF +GCSSLPPGGL NL PRLT+V+K +  DG YPSVNTC+HYLKLPEY +   L+ +LL A N+ GF+LN
Sbjct: 1677 FVSDKLTQKLVQELSDPL-LVSSNALPRWCGHLVNNYPFLFAAETRNMHLRATAFGTSRAIVWLQARRDEVLAQNRGGNSSGSGIAGPRRDDHYAEFR-VGRIKHERIKVPR----CDEMLME--------TAVR-VLKFHAARKSVLEIQYQGEEGTGLGPTLEFYALVAAEFQRKSLSMWFCDDYESSETGLDLGEGMKPPGYYVRRPGGLFPAPIPANTKESDNSCEYFHLLGIFLAKLLQDGRLVDLPISIPFLKVLVNSVVSEGANPDLGGILNLDDLEVIYPTKARFLQQLQQFVDRTKGMSE---EELDQATMAFHGDSEC--------RIDDLCLTFAVDPPSKQFTYGSV------------------DLIPNGSEIG-----VGNHNVGQYLDACLKFYLNDGIRAQVLAFREGFDLVFPLSSLRSFASAELQTLLFGEQCPEWTREDLLKYTEPKLGYTKESAGFLRFVDVLVDMTASERKAFLQFTTGCSSLPPGGLANLHPRLTVVRKVDSDDGTYPSVNTCVHYLKLPEYSSTEILRERLLAATNEKGFHLN 2193

HSP 2 Score: 81.6481 bits (200), Expect = 3.894e-11
Identity = 58/187 (31.02%), Postives = 88/187 (47.06%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINNQTMDFYVKDVEGITVTERLEQFIKLNSN--PNKIEEINDFILKIENQKLNVKTDIILTKQXXXXXXXXXXXXXXXXNYKPTLRYHVLELLGKIFQSFSHR 2012
            H +L+ A+   + D L + + S    PNF D  GQT LNW +A G +E V+ L  +G D N G+R +SLHYAA  G   V+K L+ N   +  ++D EG T  ++  +  + N       +E    F+      K  VK  I+L ++               +   P +  HVLELL  +F S   +
Sbjct:  180 HRYLIDAVRRRDTDALVDAVESGSVSPNFTDDVGQTLLNWCAAFGTIEMVSYLCNKGADVNKGQRSSSLHYAACFGRPEVVKILLRNGA-NPDLRDEEGKTPLDKARERAEENHQQVARILESPGAFLSAPGTSKEEVKCSIMLERK------------AENQTLNPEVVSHVLELLLPVFCSIFQK 353
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Cavefish
Match: hectd1 (HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-030616-153])

HSP 1 Score: 292.352 bits (747), Expect = 1.708e-78
Identity = 208/620 (33.55%), Postives = 309/620 (49.84%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPADKLTEELLEK-FRLLGIFMAKSLQDNRIMDLP--------------------------------FSELFLEILCKD---------FSDYNKKEYL------------------KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEI---FGT----TFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  RPS    RDD   P  F +GRLK    ++PR      T++  AES          ++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R SL +W+  D F ++E+              +V    GLFP P+P D    E + K F  LGIF+AK +QDNR++DLP                                FSE+ LE   ++         F + +K E++                  + F L+ P R  FL  ++    +++++L      GN++L +     +   + +    G+    + + L L+ +F P+SK++G   F   D     DD                  E VT  NAE Y++   +F M+ GI+KQ     +GFN VFP++ LS FS  E++ +LCG Q   W+  ++ NYTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLTIV+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2021 FTSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLFFTCTAFGASRAIVWLQNRREATMERSRPSTTVRRDD---PGEFRVGRLKHERVKVPRR----ETMMEWAES----------VMQIHADKKSVLEVEFQGEEGTGLGPTLEFYALVAAEFQRTSLGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFPAPFPQDNDELERITKLFLFLGIFLAKCIQDNRLVDLPISQPFFKLLCMGDIKSNMSKLLYQTHGDSDHRFSEIQLEASTEEGQDTYSMGSFDEDSKSEFILDPPKPKPPAWYHGILTWEDFELVNPHRARFLKEMKDLAVKRRQIL------GNKSLSEDEKNTRLQDLMLKNPMGSGPPLSVEDLGLNFQFCPSSKVHG---FSAVDLKPNGDD------------------EMVTMENAEEYVELMFDFCMHTGIQKQMEAFREGFNRVFPMEKLSSFSHKEVQMILCGNQSPSWTAEDIVNYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTIVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2595

HSP 2 Score: 108.997 bits (271), Expect = 6.451e-23
Identity = 75/239 (31.38%), Postives = 126/239 (52.72%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++   GG + V+SF+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLSFIRDSGHLVHKDTLHSAMAVVSRLCSKMEPQDSSLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELL 237

HSP 3 Score: 72.0182 bits (175), Expect = 1.123e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Cavefish
Match: trip12 (thyroid hormone receptor interactor 12 [Source:NCBI gene;Acc:564866])

HSP 1 Score: 194.897 bits (494), Expect = 4.719e-49
Identity = 153/526 (29.09%), Postives = 250/526 (47.53%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFL------EEENEFVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVP-FPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVK-----DGPYPSVNTCMHYLKLP 7569
            FI+  +  K   QL+D   +++ + +P+W+ E  +  PF F +D +  +     F   R+   +Q+    N +  +   +D  VAP     RL +    I R       +L +AES       ++DL      S+  LEIQ++ E GTGLGPTLEF  ++S+E  R  L +W   +  L      +E  +++FS  GLF  P+        + +   KFR LG  MAK++ D R++DLP    F + + +  S  +  + +     I P     +  +E    +K++L +  +++  R       QL   ++ + G + + L LD           T+P FP                  N+  +K     PVT +N E YL+  + + +N+G+ +QF    +GF  VFP+  L  F   EL QLLCG +   W +  L     P  GY   S++ ++  EVL   +  ++++F+QF++G   LP GG ++L P LTIV+K  +     D   PSV TC++YLKLP
Sbjct: 1170 FINSKLTAKANRQLQDPLVIMTGN-IPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDRA---MQRLLDTNPEINQSDSQDSRVAP-----RLDRKKRTINR-----EELLKQAES------VMQDL----GSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLANPKGSQEGTKYMFSSRGLFAVPFGRSTKPAHIAKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHESSISSFDLVN----IDPGVAKSIQHLEDIIRQKRRLEQ--DQSHTRETL----QLALESLNMNGCSVEDLGLDF----------TLPGFP------------------NIELKKGGKDVPVTIHNLEEYLRLVVYWTLNEGVSRQFESFREGFESVFPLHHLQYFYPEELDQLLCGSKSETWDVKTLMECCRPDHGYTHDSRAVRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLP 1633
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Cavefish
Match: wwp2 (WW domain containing E3 ubiquitin protein ligase 2 [Source:ZFIN;Acc:ZDB-GENE-000607-82])

HSP 1 Score: 89.3521 bits (220), Expect = 4.205e-17
Identity = 81/320 (25.31%), Postives = 132/320 (41.25%), Query Frame = 1 
Query: 6628 PADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPT--QGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNL----KPRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            PA  +  + L  FR +G F+A +L   + +D  F+  F + +       NKK  LK    I PE   F  SI                     +W   + L+   +E++         DME L                            +     + D  +E VT +N E Y+    ++   +G+++Q    +DGFNEV P++ L  F   EL+ +LCG Q      I+L ++ + T  + Y   SK   +F +V+ E++  +R   +QF++G   LP GG   L     P+   + K  K+   P  +TC + L LP
Sbjct:  562 PASSINPDHLNYFRFIGRFIAMALYHGKFIDTGFTLPFYKRML------NKKPTLKDLESIDPE---FYNSI---------------------MWVKENDLEECGVELY------FAQDMEML--------------------------GKVSTHSLKDDGENELVTSHNKEEYIGLLTDWRFTRGVEEQTKAFLDGFNEVVPLEWLRYFDEKELELMLCGMQE-----IDLSDWQKNTIYRHYTKNSKQIHWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLP 814
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Cavefish
Match: itchb (E3 ubiquitin-protein ligase Itchy [Source:NCBI gene;Acc:103022206])

HSP 1 Score: 82.0333 bits (201), Expect = 6.952e-15
Identity = 49/153 (32.03%), Postives = 82/153 (53.59%), Query Frame = 1 
Query: 7123 VTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNL----KPRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            VTE N E Y++    + +++G+++Q     +GFNEV P + L  F + EL+ LLCG Q I   L + Q  T   + Y   +K   +F +++ E++  +R   +QF++G   LP GG  +L     P+   ++K  K+   P  +TC + L LP
Sbjct:  606 VTEENKEEYIRLVAEWRLSRGVEEQTQAFFEGFNEVLPQQYLQYFDAKELEVLLCGMQEI--DLADWQRNT-IYRHYTRGNKQIVWFWQLVKEMDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKTGKENWLPRSHTCFNRLDLP 755
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Cavefish
Match: itchb (E3 ubiquitin-protein ligase Itchy [Source:NCBI gene;Acc:103022206])

HSP 1 Score: 81.2629 bits (199), Expect = 1.370e-14
Identity = 48/155 (30.97%), Postives = 83/155 (53.55%), Query Frame = 1 
Query: 7123 VTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPT--QGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNL----KPRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            VTE N E Y++    + +++G+++Q     +GFNEV P + L  F + EL+ LLCG Q      I+L ++   T  + Y   +K   +F +++ E++  +R   +QF++G   LP GG  +L     P+   ++K  K+   P  +TC + L LP
Sbjct:  700 VTEENKEEYIRLVAEWRLSRGVEEQTQAFFEGFNEVLPQQYLQYFDAKELEVLLCGMQE-----IDLADWQRNTIYRHYTRGNKQIVWFWQLVKEMDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKTGKENWLPRSHTCFNRLDLP 849
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Sea Lamprey
Match: wwp2 (WW domain containing E3 ubiquitin protein ligase 2 [Source:ZFIN;Acc:ZDB-GENE-000607-82])

HSP 1 Score: 82.8037 bits (203), Expect = 8.473e-16
Identity = 84/320 (26.25%), Postives = 136/320 (42.50%), Query Frame = 1 
Query: 6628 PADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPT--QGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNL----KPRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            PA  +  + L  FR +G F+A +L   + +D  FS  F + +       NKK  +K    I PE   F  S+                     +W   + ++   +E+F        +DME L      G V               SHD       + D     VTE N E Y+     +  ++G+++Q    +DGF+EV P++ L  F   EL+ +LCG Q      I+L ++   T  + Y  +SK   +F +V+ E++  +R   +QF++G   LP GG   L     P+   ++K  K+   P  +TC + L LP
Sbjct:  655 PASSINPDHLAYFRFIGRFIAMALYHGKFIDTGFSLPFYKRM------LNKKLTIKDLESIDPE---FYNSL---------------------IWLRDNNIEECGLEMF------FSVDMELL------GKV--------------SSHD------LKPDGSDILVTEENKEEYIGLMTEWRFSRGVEEQTKAFLDGFSEVVPLQWLLYFDERELEVMLCGMQE-----IDLADWQRSTIYRHYNRSSKQISWFWQVVKEMDNEKRLRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIEKVGKETWLPRSHTCFNRLDLP 907
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Sea Lamprey
Match: ube3c (ubiquitin protein ligase E3C [Source:ZFIN;Acc:ZDB-GENE-040426-1211])

HSP 1 Score: 72.0182 bits (175), Expect = 2.044e-12
Identity = 42/150 (28.00%), Postives = 71/150 (47.33%), Query Frame = 1 
Query: 7120 PVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            PVT  N   Y+    ++ +N+ I++       G   V  ++ L MF   EL+ LL G Q +   L +L+N+T  + GY +     + F  V+      +++  ++F++ CS  P  G K L P   +          P+ +TCM+ LKLP
Sbjct:  918 PVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLATVINLEWLRMFDEQELQVLLSGAQ-VPIDLQDLKNFTNYSGGYTADHPVIKVFWHVVEGFTDEQKRKLLKFVTSCSRPPLLGFKELFPAFCVHNGGADPERLPTASTCMNLLKLP 1066
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Sea Lamprey
Match: ube3a (ubiquitin protein ligase E3A [Source:ZFIN;Acc:ZDB-GENE-041114-190])

HSP 1 Score: 70.0922 bits (170), Expect = 6.183e-12
Identity = 45/154 (29.22%), Postives = 83/154 (53.90%), Query Frame = 1 
Query: 7120 PVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVF---PIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGP-YPSVNTCMHYLKLP 7569
            PVT +N + ++     + +N+ ++KQF     GF+ V    P+K+L  F   E++ L+CG + + +  +E  + TE   G+  +S+  + F + + +  + ++++F+QF +G    P GGL  LK    I+ KN  D    P+ +TC + L LP
Sbjct:  696 PVTNDNKKEFVDLYAEYILNQSVEKQFKAFRRGFHMVTSESPLKAL--FRPEEVELLVCGSRVLDFHALE--DATEYDGGFNKSSRVIRDFWDTVHDFCEDKKRLFLQFTTGTDRAPVGGLGKLK---MIIAKNGPDSDRLPTAHTCFNVLLLP 842
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007716.1 (pep scaffold:Pmarinus_7.0:GL480432:8:26910:-1 gene:ENSPMAG00000006962.1 transcript:ENSPMAT00000007716.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 69.707 bits (169), Expect = 9.893e-12
Identity = 41/109 (37.61%), Postives = 58/109 (53.21%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELL-LSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINNQTMDFYVKDVEGITVTERLEQ 1781
            H  L+  I + + D L + +     F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +   +  ++D +G T  ++  +
Sbjct:   90 HRQLIDCIRSKDTDALIDAIDTGAAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRHGA-NPDLRDEDGKTPLDKARE 197
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Sea Lamprey
Match: nedd4a (NEDD4 E3 ubiquitin protein ligase a [Source:ZFIN;Acc:ZDB-GENE-051005-2])

HSP 1 Score: 64.6994 bits (156), Expect = 2.161e-10
Identity = 37/153 (24.18%), Postives = 76/153 (49.67%), Query Frame = 1 
Query: 7123 VTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNL----KPRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            VT  N + Y++  + +   + ++KQ    ++GF+E+ P+  + +F  +EL+ L+CG   +   + + + +T     Y +     Q+F + +L ++  +R   +QF++G S +P  G   L     P+L  ++        P  +TC + L LP
Sbjct:  318 VTNENKKEYIELVIQWRFVERVQKQINAFMEGFSELIPMDLIKIFDENELELLMCGLGDV--DVNDWRQHTIYKNSYCANHPVIQWFWKAVLLMDGEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEMWSTSEKLPRAHTCFNRLDLP 468
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Yeast
Match: UFD4 (Ubiquitin-protein ligase (E3); interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000001493])

HSP 1 Score: 177.948 bits (450), Expect = 8.608e-45
Identity = 144/524 (27.48%), Postives = 242/524 (46.18%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMW------VHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTI--NEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGP-----YPSVNTCMHYLKLP 7569
            FI+  +  K+  QL++   +++   LP W +   +++PF+F +D ++  L+   FG  R +   + ++K + D      R+D       LGR+ +   +I R              ++IF + ++ +L  +  S + LEI++ +E GTGLGPTLEF +++SK F R SL MW        ++  ++  ++++ +   LFP P       E+++E F  LG F+A+SL DNRI+D  FS++F E+L         +        +  +    L+ IEL      K LK I  N+  N TL  +      L   + G        D+E +P                            CN         + +  +N E Y+   ++  + KGI+KQ    I+GF++VF  + + +    EL  +  G     WS+  L        GY   S     F+ ++    + ER++F+QF++G   LP GG K+L P+ T+V K+ +DG       PSV TC +YLKLP
Sbjct: 1014 FINSKLSAKLARQLDEPL-VVASGALPDWSLFLTRRFPFLFPFDTRMLFLQCTSFGYGRLIQLWKNKSKGSKDL-----RND--EALQQLGRITRRKLRISR--------------KTIFATGLK-ILSKYGSSPDVLEIEYQEEAGTGLGPTLEFYSVVSKYFARKSLNMWRCNSYSYRSEMDVDTTDDYITTL--LFPEPLNPFSNNEKVIELFGYLGTFVARSLLDNRILDFRFSKVFFELL--------HRMSTPNVTTVPSDVETCLLMIELVDPLLAKSLKYIVANKDDNMTLESL-----SLTFTVPGND------DIELIPGG--------------------------CN---------KSLNSSNVEEYIHGVIDQILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIF-GRVEEDWSMATLYTNLNAEHGYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAEDGLTADEYLPSVMTCANYLKLP 1457
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Yeast
Match: HUL4 (Protein with similarity to hect domain E3 ubiquitin-protein ligases; not essential for viability; found in association with Trf4 in TRAMP complex [Source:SGD;Acc:S000003797])

HSP 1 Score: 78.9518 bits (193), Expect = 7.781e-15
Identity = 80/381 (21.00%), Postives = 167/381 (43.83%), Query Frame = 1 
Query: 6442 EELEIQFDQEEGTGLGPTL-EFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKD---FSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFP-IKSLSMFSSSELKQLLCG-EQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKL 7566
            + L I+F  E G   G    E+  +L+K    P   +++    +++E +   F+   + P  +   K     LE + L G+ M  ++ ++ I+DL F +   + LC +   F DY+                      ELF E  + L+K +N           D  +    ++F  TF+                       ++ W  +DS S  +   +   ++  + P+T++N   ++ + + F + K I+ Q+ + + GF  VF    S+ +F+S EL++L+CG E+  K+    L++ T+   G+   S++  +F E++   +   +K  +QF++    +P  G+  +  +++++  +  D   P  +TC + + L
Sbjct:  547 KSLRIEFVNEPGIDAGGLRKEWFFLLTKSLFNPMNGLFI----YIKESSRSWFA---IDPPNFDKSKGKNSQLELYYLFGVVMGLAIFNSTILDLQFPKALYKKLCSEPLSFEDYS----------------------ELFPETSRNLIKMLN--------YTEDNFE----DVFSLTFET-------------------TYRNNNWILNDSKSSKEYVTVELCENGRNVPITQSNKHEFVMKWVEFYLEKSIEPQYNKFVSGFKRVFAECNSIKLFNSEELERLVCGDEEQTKFDFKSLRSVTKYVGGFSDDSRAVCWFWEIIESWDYPLQKKLLQFVTASDRIPATGISTIPFKISLLGSHDSD-DLPLAHTCFNEICL 866
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Yeast
Match: RSP5 (NEDD4 family E3 ubiquitin ligase; regulates processes including: MVB sorting, the heat shock response, transcription, endocytosis and ribosome stability; ubiquitinates Sec23p, Sna3p, Ste4p, Nfi1p, Rpo21p and Sem1p; autoubiquitinates; deubiquitinated by Ubp2p; regulated by SUMO ligase Siz1p, in turn regulates Siz1p SUMO ligase activity; required for efficient Golgi-to-ER trafficking in COPI mutants; mutant tolerates aneuploidy; human homolog implicated in Liddle syndrome [Source:SGD;Acc:S000000927])

HSP 1 Score: 68.5514 bits (166), Expect = 1.069e-11
Identity = 43/176 (24.43%), Postives = 91/176 (51.70%), Query Frame = 1 
Query: 7060 DSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPT--QGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLK----PRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            D +   ++  +  + D  +  VT+ N + Y++    + +   +++QF   +DGFNE+ P   +++F   EL+ L+ G      + I+++++ + T  +GY  + +  Q+F + + E +  +R   +QF +G S +P  G K+L+    PR   ++K  +    P  +TC + + LP
Sbjct:  614 DDERFGEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLIGG-----IAEIDIEDWKKHTDYRGYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLP 784
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Yeast
Match: HUL5 (Multiubiquitin chain assembly factor (E4); proteasome processivity factor that elongates polyUb chains on substrates, opposing Ubp6p, a branched polyubiquitin protease; required for retrograde transport of misfolded proteins during ERAD; required for ubiquitination of a subset of cytosolic misfolded proteins upon heat shock [Source:SGD;Acc:S000003109])

HSP 1 Score: 61.6178 bits (148), Expect = 1.755e-9
Identity = 43/149 (28.86%), Postives = 74/149 (49.66%), Query Frame = 1 
Query: 7123 VTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            VT++N   Y+ +  ++ +NK   K  +    G + +     + MF+S EL+ L+ GE+     L +L++ TE   GY    ++   F EVL E    E+  F++F++     P  G K L P+  I     +    P+ +TC++ LKLP
Sbjct:  739 VTKDNVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEMFNSIELQMLISGERD-NIDLDDLKSNTE-YGGYKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQGFKALDPKFGIRNAGTEKYRLPTASTCVNLLKLP 885
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Yeast
Match: TOM1 (E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones; interacts with Dia2p and is required for Dia2p degradation; required to target Cdc6p for ubiquitin-mediated destruction during G1 phase [Source:SGD;Acc:S000002865])

HSP 1 Score: 60.077 bits (144), Expect = 5.876e-9
Identity = 39/156 (25.00%), Postives = 72/156 (46.15%), Query Frame = 1 
Query: 7123 VTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQ--GYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKP-----RLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            VTE N ++Y+++ + + +   +K+Q    + GF  +     +++F   EL+ L+ G        I++ ++   T    Y +T K   YF   +   +  ER   +QF++G S +P  G K L       + +I +        PS +TC + L LP
Sbjct: 3092 VTEANKQDYVKKVVEYKLQTSVKEQMDNFLVGFYALISKDLITIFDEQELELLISG-----LPDIDVDDWKNNTTYVNYTATCKEVSYFWRAVRSFDAEERAKLLQFVTGTSKVPLNGFKELSGVNGVCKFSIHRDFGSSERLPSSHTCFNQLNLP 3242
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Nematostella
Match: EDO35037 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SML1])

HSP 1 Score: 209.92 bits (533), Expect = 3.664e-54
Identity = 155/525 (29.52%), Postives = 263/525 (50.10%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTD---SFLEEEN---EFVFSKNGLFPYPWPADK---LTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVK-----DGPYPSVNTCMHYLKLP 7569
            F +Q +  KVL QL+D  ++++ +  PSW++E P+K  F+F ++ +  +     F   R++  LQ+      D I      D VAP     RL +  + + R       +L++AE        ++DL      S+  LEIQ+  E GTGLGPTLEF  ++SKEF R S+ MW  T+      E+ +   ++V+S++GLFP P P +    +   L  KFR LG F+ ++L D R++D+PFS  F + +    + ++ ++       I P     +  ++    +K +L K      + +L     QL    + + G + + L LD               P Y                N+  +K+  + PVT +N E Y++  +++ + +G+++Q     +GF+ VFP+ +L ++ +  + QLLCG    KW + EL     P  GY   S++ +   E+L E +  ++++F+QF++G   LP GG ++L P LTIV+K  +     D   PSV TC++YLKLP
Sbjct: 1097 FANQKLAAKVLRQLQDPIAVMTGN-FPSWVLELPRKCSFLFPFECRQQLFFCTSFDRERAMSKLQESIP---DLINTEM-SDRVAP-----RLDRKKSTVSR-----KDLLSQAEK------IIQDL----GSSQSILEIQYQSEVGTGLGPTLEFYALVSKEFQRSSMEMWRGTEVAPPVTEDADGGIKYVYSESGLFPIPIPRNARVAMVSRLKSKFRFLGRFLGRALLDFRMVDIPFSCAFYKWMLGFEATFDYRDLFD----IDPVLAKSISQLQGLVRQKHRLEK------DSSLTPESLQLAVENLTLDGASVEDLGLDF------------VLPGY---------------TNIELKKNGRNIPVTIHNLEKYIKLVVHWTLVEGVERQMQAFQEGFDSVFPLTNLKVYYAVNMDQLLCGSVGQKWEVKELVESCRPDHGYSHDSRAIKCLFEILSEYDADQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFEPPLSADNYLPSVMTCVNYLKLP 1559
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Nematostella
Match: EDO41212 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4U7])

HSP 1 Score: 88.5817 bits (218), Expect = 6.559e-18
Identity = 71/259 (27.41%), Postives = 125/259 (48.26%), Query Frame = 2 
Query:   95 MDDVESPYILLNWL---QSGSEEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL-EMTMVQLKMDNQTSHNQNP 859
            M DV+ P  LL WL   Q    +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G+L ++C RL    +++    DL +Q +K+LE +C R+  ++   GG    ++F+      +H DT+ S   ++ ++  +++P D  L    + LS   +H D  + + +L C  S+      + +    L    +  +LL ++       +  TS +  P
Sbjct:    1 MVDVD-PDTLLEWLNMGQGDERDMQLIALEQLCMLLLMSDNIDRCFESCPPRTFLPALCRIFLDECAPENVLEVTARAITYYLD-VSAECTRRIVAVDGALKSLCNRLVIVELSSRTSKDLGEQCVKVLELICTREAGAVFEAGGLQCALTFIREFGSAVHKDTLHSAMNVVTRLCGRMEPQDQNLETCVKSLSTLLEHEDKYVSDGALRCFASLADRFTRRVVDPAPLAKHGLTGELLRQLASAAGANERSTSSSATP 257

HSP 2 Score: 76.2554 bits (186), Expect = 6.794e-14
Identity = 59/181 (32.60%), Postives = 90/181 (49.72%), Query Frame = 3 
Query: 1167 VIIDLILCIIRGSHQFLHNLLVKSKLVDIILEITWQYDSSSISILQLIEGMFDQIME--RTTYKSNENIQRYKLSTALGMRVIHNRMYSEEMIQQYWNYHEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIK 1703
             I+ L++ + RGS    H+LL +S+L D I +     +   +  ++L++ +   + E  +   KS+ ++ R       G+R       S E        H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G LE V  L  RG D N G+R +SLHYAA  G  +V K
Sbjct:  268 TIVSLLITLCRGSPAITHDLL-RSELPDAIEKALQGEERCILDTMRLVDLLLVLLFEGRQALPKSSVSLPR---GGGPGIRRFDG---SSE------RSHRQLIDCIRSKDTDALIDAIENGGFEVNFMDDVGQTLLNWASAFGTLEMVEYLCERGADVNRGQRSSSLHYAACFGRPAVAK 435
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Nematostella
Match: EDO30268 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T196])

HSP 1 Score: 79.7221 bits (195), Expect = 1.170e-14
Identity = 48/149 (32.21%), Postives = 73/149 (48.99%), Query Frame = 1 
Query: 7123 VTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
            VTE N   YL     + + + ++K+    I G NE+ P   L MF  +EL+ L+CG  HI  + ++  ++     G   T K   +F  ++  L Q E    +QF++G S LPPGG   L P+L I          P+ +TC + L LP
Sbjct:  589 VTEQNKCEYLNLMARYKLVESVQKEVEAFIQGLNELVPDNLLGMFDENELELLMCGTGHISVADMKAHHHVLAGGGQRFT-KIMDWFWTIVSSLTQEELARLLQFVTGSSQLPPGGFAELSPQLQISYIATSQA-LPTAHTCFNQLCLP 735
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Nematostella
Match: EDO34473 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP65])

HSP 1 Score: 77.0258 bits (188), Expect = 2.959e-14
Identity = 54/173 (31.21%), Postives = 88/173 (50.87%), Query Frame = 1 
Query: 7120 PVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLK-----PRLTIVKKNVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQ 7623
            PVTE N   Y++      M   I+KQ    ++GF E+ P + +S+F+  EL+ L+ G  +I   L +L+++ E    Y   S   Q+F   L   +Q  R  F+QF++G S +P  G   L+      +  I + +      PS +TC + L LP YET  +L+  L +AC++
Sbjct:  223 PVTEENKREYVKLVCQMKMTGAIRKQIDSFLEGFYEIIPKRLISIFNEQELELLISGLPNI--DLDDLKSHIE-YHKYNENSLQIQWFWRALRSFDQAARAKFLQFVTGTSKVPLQGFAALEGMNGFQKFQIHRDDRNTDRLPSAHTCFNQLDLPAYETYDKLRTMLKKACDE 392
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Nematostella
Match: EDO49327 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHD5])

HSP 1 Score: 75.485 bits (184), Expect = 7.672e-14
Identity = 45/156 (28.85%), Postives = 79/156 (50.64%), Query Frame = 1 
Query: 7120 PVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPT--QGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNL----KPRLTIVKKNVKDGPYPSVNTCMHYLKLP 7569
             VTE N E Y+     + +N+GI++Q    ++G +EV P+  +  F   EL+ +LCG Q      I+++++ + T  + Y   SK   +F + +   +  +R   +QF++G   LP GG   L     P+   ++K  K+   P  +TC + L LP
Sbjct:  189 AVTEENKEEYISLMTEWRLNRGIEEQTRAFLEGMHEVLPLYWIQYFDERELELMLCGMQE-----IDVEDWQQNTVYRHYTRNSKQVMWFWQAVKAYDNEKRIRLLQFVTGTCRLPVGGFTELMGDNGPQKFCIEKVGKETWLPRSHTCFNRLDLP 339
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Medaka
Match: hectd1 (HECT domain E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:101168256])

HSP 1 Score: 291.582 bits (745), Expect = 2.233e-78
Identity = 227/715 (31.75%), Postives = 345/715 (48.25%), Query Frame = 1 
Query: 5695 FPIANYVLKMLPSPDPILNI-----YPIDNVSEIWHSQFTLFYGFC--DKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIF-----SILHHLKCSQLRFIEKTKNQVMKLQYL--------------DVDWLDL-----YFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPAD-KLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKD--FSDYNKKEYLKRF--MLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLC------------LDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
             P++NY L +      +L +        D +  IW   +T+ Y       K   +   + F   + + +     +   AN+  +I      ++L    CSQ     +   Q++++ Y+              DVD L        F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  RPS    RDD   P  F +GRLK    ++PR    G +++  AES          ++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R SL +W+  D F ++E+              +V    GLFP P+P D +  E +   F  LGIF+AK +QDNR++DLP S+ F ++LC     S+ +K  Y  R        ER   L+  E+  E   +  +     G+       D +           F G+             L+ +F P+SKI+G         ++  D   + DD            E V+  NAE Y++   +F M+ GI+KQ     +GFN VFP++ LS FS  E++ +LCG Q   W+  ++ +YTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLTIV+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 1622 IPLSNYKLTIFYYVQRLLQLSCNGAVKTDKLRRIWEPTYTIMYRELKDSDKEKESGKMDLFEHVVGSRSGGLSPSSGSANQSSEILGWAKEAVLAKAGCSQNACGVEDVLQLLRILYVIGRDSTAGGRTLQEDVDELQFNSPPEEFSSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATMERSRPSTTVRRDD---PGEFRVGRLKHERVKVPR----GESMMEWAES----------VMQIHANRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTSLGIWLCDDDFPDDESRQVDLGGGLKPPGFYVQRSCGLFPAPFPQDSEELERITRLFHFLGIFLAKCIQDNRLVDLPVSQPFFKLLCMGDIKSNMSKLLYQSRGSPQGHLSERAPLLLLTEVQSEASTEESQETYSVGSFDEDSKSDFIMDPPKPKPPAWFHGIMSWDDFHLVNPHRLNFQFCPSSKIHG---------FFAVDLKPNGDD------------EMVSLENAEEYVELMFDFCMHAGIQKQMEAFREGFNRVFPMEKLSSFSQKEVQMILCGNQSPCWTADDIISYTEPKLGYTRDSPGFLRFIRVLCGMSTDERKAFLQFTTGCSTLPPGGLANLHPRLTIVRKVDATDSSYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2297

HSP 2 Score: 72.0182 bits (175), Expect = 1.097e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  197 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 283
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Medaka
Match: trip12 (thyroid hormone receptor interactor 12 [Source:NCBI gene;Acc:101175421])

HSP 1 Score: 188.348 bits (477), Expect = 4.750e-47
Identity = 149/526 (28.33%), Postives = 247/526 (46.96%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFL------EEENEFVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVP-FPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVK-----DGPYPSVNTCMHYLKLP 7569
            FI+  +  K   QL+D   +++ + +P+W++E  +  PF F +D +  +     F   R+   +Q+    N +  +   +D  VAP     RL +    I R       +L +AES       ++DL      S+  LEIQ++ E GTGLGPT EF  ++S+E  R  L +W   +  L      +E  +++FS  GLF  P+        + +   KFR LG  MAK++ D R++DLP    F + + +  +  +  + +     I P     +  +E    +K++L +      +R+  +   Q    ++ + G + + L LD           T+P FP                  N+  +K      VT  N E YL+  + + +N+G+ +QF    +GF  VFP+  L  F   EL QLLCG +   W +  L     P  GY   S++ ++  EVL   +  ++++F+QF++G   LP GG ++L P LTIV+K  +     D   PSV TC++YLKLP
Sbjct: 1491 FINSKLTAKANRQLQDPLVIMTGN-IPTWLIELGKSCPFFFPFDTRQMLFYVTAFDRDRA---MQRLLDTNPEINQSDSQDSRVAP-----RLDRKKRTINR-----EELLKQAES------VIQDL----GSSRAMLEIQYENEVGTGLGPTQEFYALVSQELQRADLGLWRGEEVTLTNPKGNQEGTKYMFSSRGLFAVPFGRTTKPAHIAKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHETSVSSHDLVN----IDPGVAKSIQHLEDIIRQKKRLEQ------DRSQTRETLQQALESLNMNGCSVEDLGLDF----------TLPGFP------------------NIELKKGGKDVAVTIYNLEEYLRLVVYWTLNEGVSRQFESFREGFESVFPLHHLQYFYPEELDQLLCGSKSETWDVKTLMECCRPDHGYTHDSRAIRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLP 1954
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Medaka
Match: trip12 (thyroid hormone receptor interactor 12 [Source:NCBI gene;Acc:101175421])

HSP 1 Score: 187.963 bits (476), Expect = 7.207e-47
Identity = 149/526 (28.33%), Postives = 247/526 (46.96%), Query Frame = 1 
Query: 6037 FISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFL------EEENEFVFSKNGLFPYPWPADKLTEELLE---KFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVP-FPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVK-----DGPYPSVNTCMHYLKLP 7569
            FI+  +  K   QL+D   +++ + +P+W++E  +  PF F +D +  +     F   R+   +Q+    N +  +   +D  VAP     RL +    I R       +L +AES       ++DL      S+  LEIQ++ E GTGLGPT EF  ++S+E  R  L +W   +  L      +E  +++FS  GLF  P+        + +   KFR LG  MAK++ D R++DLP    F + + +  +  +  + +     I P     +  +E    +K++L +      +R+  +   Q    ++ + G + + L LD           T+P FP                  N+  +K      VT  N E YL+  + + +N+G+ +QF    +GF  VFP+  L  F   EL QLLCG +   W +  L     P  GY   S++ ++  EVL   +  ++++F+QF++G   LP GG ++L P LTIV+K  +     D   PSV TC++YLKLP
Sbjct: 1569 FINSKLTAKANRQLQDPLVIMTGN-IPTWLIELGKSCPFFFPFDTRQMLFYVTAFDRDRA---MQRLLDTNPEINQSDSQDSRVAP-----RLDRKKRTINR-----EELLKQAES------VIQDL----GSSRAMLEIQYENEVGTGLGPTQEFYALVSQELQRADLGLWRGEEVTLTNPKGNQEGTKYMFSSRGLFAVPFGRTTKPAHIAKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHETSVSSHDLVN----IDPGVAKSIQHLEDIIRQKKRLEQ------DRSQTRETLQQALESLNMNGCSVEDLGLDF----------TLPGFP------------------NIELKKGGKDVAVTIYNLEEYLRLVVYWTLNEGVSRQFESFREGFESVFPLHHLQYFYPEELDQLLCGSKSETWDVKTLMECCRPDHGYTHDSRAIRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLP 2032
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Medaka
Match: hectd1 (HECT domain E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:101168256])

HSP 1 Score: 172.555 bits (436), Expect = 3.547e-42
Identity = 106/290 (36.55%), Postives = 162/290 (55.86%), Query Frame = 1 
Query: 6799 FMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQL--------KCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F L+ P R  FL  ++     ++++L + + + +    ++ D +          L++E  G       L+ +F P+SKI+G         ++  D   + DD            E V+  NAE Y++   +F M+ GI+KQ     +GFN VFP++ LS FS  E++ +LCG Q   W+  ++ +YTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLTIV+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2255 FHLVNPHRASFLKEVKELAVRRRQILTSKSLSEDEKNTRLQDLMLRNPLGSGPPLSVEDLG-------LNFQFCPSSKIHG---------FFAVDLKPNGDD------------EMVSLENAEEYVELMFDFCMHAGIQKQMEAFREGFNRVFPMEKLSSFSQKEVQMILCGNQSPCWTADDIISYTEPKLGYTRDSPGFLRFIRVLCGMSTDERKAFLQFTTGCSTLPPGGLANLHPRLTIVRKVDATDSSYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2516

HSP 2 Score: 152.14 bits (383), Expect = 5.377e-36
Identity = 124/426 (29.11%), Postives = 195/426 (45.77%), Query Frame = 1 
Query: 5695 FPIANYVLKMLPSPDPILNI-----YPIDNVSEIWHSQFTLFYGFC--DKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIF-----SILHHLKCSQLRFIEKTKNQVMKLQYL--------------DVDWLDL-----YFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPAD-KLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERG 6825
             P++NY L +      +L +        D +  IW   +T+ Y       K   +   + F   + + +     +   AN+  +I      ++L    CSQ     +   Q++++ Y+              DVD L        F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  RPS    RDD   P  F +GRLK    ++PR    G +++  AES          ++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R SL +W+  D F ++E+              +V    GLFP P+P D +  E +   F  LGIF+AK +QDNR++DLP S+ F ++LC      N  +      L+Y  RG
Sbjct: 1788 IPLSNYKLTIFYYVQRLLQLSCNGAVKTDKLRRIWEPTYTIMYRELKDSDKEKESGKMDLFEHVVGSRSGGLSPSSGSANQSSEILGWAKEAVLAKAGCSQNACGVEDVLQLLRILYVIGRDSTAGGRTLQEDVDELQFNSPPEEFSSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATMERSRPSTTVRRDD---PGEFRVGRLKHERVKVPR----GESMMEWAES----------VMQIHANRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTSLGIWLCDDDFPDDESRQVDLGGGLKPPGFYVQRSCGLFPAPFPQDSEELERITRLFHFLGIFLAKCIQDNRLVDLPVSQPFFKLLCMGDIKSNMSK------LLYQSRG 2189

HSP 3 Score: 106.686 bits (265), Expect = 3.531e-22
Identity = 74/239 (30.96%), Postives = 125/239 (52.30%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGS---EEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLL 802
            M DV+ P  LL WLQ G     +MQL ALEQLC+ LL  ++ +   +  PP T++P L  +  D      +LE   R +TYY+  +  E   R+V   G++ A+C RL    + N    DL +Q +K+LE +C R++ ++    G + V+SF+  +  ++H DT+ S   ++ ++  K++P D  L    E LS+  KH D ++ + +L C  S+      + +    L    + ++LL
Sbjct:    1 MADVD-PDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLD-VSAECTRRIVGVDGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEASGLNCVLSFIRDSGHLVHKDTLHSAMAVVSRLCSKMEPQDSSLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAKHGLTEELL 237

HSP 4 Score: 72.0182 bits (175), Expect = 1.111e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  363 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 449
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Medaka
Match: hectd1 (HECT domain E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:101168256])

HSP 1 Score: 172.555 bits (436), Expect = 3.808e-42
Identity = 105/286 (36.71%), Postives = 162/286 (56.64%), Query Frame = 1 
Query: 6799 FMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGT----TFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKK-NVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            F L+ P R  FL  ++     ++++L + + + +    ++ D    +     G+    + + L L+ +F P+SKI+G         ++  D   + DD            E V+  NAE Y++   +F M+ GI+KQ     +GFN VFP++ LS FS  E++ +LCG Q   W+  ++ +YTEP  GY   S  +  F+ VL  ++  ERK F+QF +GCS+LPPGGL NL PRLTIV+K +  D  YPSVNTC+HYLKLPEY ++  ++ +LL A  + GF+LN
Sbjct: 2028 FHLVNPHRASFLKEVKELAVRRRQILTSKSLSEDEKNTRLQD---LMLRNPLGSGPPLSVEDLGLNFQFCPSSKIHG---------FFAVDLKPNGDD------------EMVSLENAEEYVELMFDFCMHAGIQKQMEAFREGFNRVFPMEKLSSFSQKEVQMILCGNQSPCWTADDIISYTEPKLGYTRDSPGFLRFIRVLCGMSTDERKAFLQFTTGCSTLPPGGLANLHPRLTIVRKVDATDSSYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN 2289

HSP 2 Score: 152.14 bits (383), Expect = 6.438e-36
Identity = 119/403 (29.53%), Postives = 188/403 (46.65%), Query Frame = 1 
Query: 5695 FPIANYVLKMLPSPDPILNI-----YPIDNVSEIWHSQFTLFYGFC--DKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIF-----SILHHLKCSQLRFIEKTKNQVMKLQYL--------------DVDWLDL-----YFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSF---RDDLVAPFHF-LGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENE-------------FVFSKNGLFPYPWPAD-KLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILC 6756
             P++NY L +      +L +        D +  IW   +T+ Y       K   +   + F   + + +     +   AN+  +I      ++L    CSQ     +   Q++++ Y+              DVD L        F S+ +  K+L Q+E+  +L S   LP W  +   K PF+  ++ +        FG SR+++WLQ R +   +  RPS    RDD   P  F +GRLK    ++PR    G +++  AES          ++  HA  K  LE++F  EEGTGLGPTLEF  +++ EF R SL +W+  D F ++E+              +V    GLFP P+P D +  E +   F  LGIF+AK +QDNR++DLP S+ F ++LC
Sbjct: 1561 IPLSNYKLTIFYYVQRLLQLSCNGAVKTDKLRRIWEPTYTIMYRELKDSDKEKESGKMDLFEHVVGSRSGGLSPSSGSANQSSEILGWAKEAVLAKAGCSQNACGVEDVLQLLRILYVIGRDSTAGGRTLQEDVDELQFNSPPEEFSSKKITTKILQQIEEPLALAS-GALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATMERSRPSTTVRRDD---PGEFRVGRLKHERVKVPR----GESMMEWAES----------VMQIHANRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTSLGIWLCDDDFPDDESRQVDLGGGLKPPGFYVQRSCGLFPAPFPQDSEELERITRLFHFLGIFLAKCIQDNRLVDLPVSQPFFKLLC 1945

HSP 3 Score: 72.0182 bits (175), Expect = 1.096e-11
Identity = 38/87 (43.68%), Postives = 49/87 (56.32%), Query Frame = 3 
Query: 1458 HEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINN 1718
            H  L+  I + + D L + + +  F+ NF D  GQT LNWASA G  E V  L  RG D N G+R +SLHYAA  G   V K L+ +
Sbjct:  197 HRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRH 283
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Planmine SMEST
Match: SMESG000022351.1 (SMESG000022351.1)

HSP 1 Score: 2251.48 bits (5833), Expect = 0.000e+0
Identity = 1127/1130 (99.73%), Postives = 1129/1130 (99.91%), Query Frame = 1 
Query: 4252 DQIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQXXXXXXXXXXXXXMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            +QIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQFSKSIDDFKKSFSMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDI NMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHI+WSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPEYETKSELKLKLLEACNQIGFYLN
Sbjct:  112 NQIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQFSKSIDDFKKSFSMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDIYNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIQWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPEYETKSELKLKLLEACNQIGFYLN 1241
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Planmine SMEST
Match: SMESG000022351.1 (SMESG000022351.1)

HSP 1 Score: 2250.71 bits (5831), Expect = 0.000e+0
Identity = 1127/1130 (99.73%), Postives = 1129/1130 (99.91%), Query Frame = 1 
Query: 4252 DQIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQXXXXXXXXXXXXXMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            +QIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQFSKSIDDFKKSFSMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDI NMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHI+WSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPEYETKSELKLKLLEACNQIGFYLN
Sbjct:  103 NQIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQFSKSIDDFKKSFSMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDIYNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIQWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPEYETKSELKLKLLEACNQIGFYLN 1232
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Planmine SMEST
Match: SMESG000022351.1 (SMESG000022351.1)

HSP 1 Score: 2249.55 bits (5828), Expect = 0.000e+0
Identity = 1127/1130 (99.73%), Postives = 1129/1130 (99.91%), Query Frame = 1 
Query: 4252 DQIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQXXXXXXXXXXXXXMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            +QIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQFSKSIDDFKKSFSMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDI NMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHI+WSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPEYETKSELKLKLLEACNQIGFYLN
Sbjct:   75 NQIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQFSKSIDDFKKSFSMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDIYNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIQWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPEYETKSELKLKLLEACNQIGFYLN 1204
[Close]
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Planmine SMEST
Match: SMESG000022351.1 (SMESG000022351.1)

HSP 1 Score: 2221.82 bits (5756), Expect = 0.000e+0
Identity = 1112/1115 (99.73%), Postives = 1114/1115 (99.91%), Query Frame = 1 
Query: 4297 VLPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQXXXXXXXXXXXXXMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPXXXXXXXXXXXXXXACNQIGFYLN 7641
            +LPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQFSKSIDDFKKSFSMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDI NMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHI+WSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPEYETKSELKLKLLEACNQIGFYLN
Sbjct:  103 ILPGPDWVFDNRESYKIGKTLTLIKNGTVLVEWLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIESRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPSISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFELTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQFSKSIDDFKKSFSMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDIEMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNNKFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENLNYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFNDFKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDPILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATDKNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFISQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKAFWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPRPYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGPTLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKLTEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYLKRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLAIEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDIYNMGYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIKSLSMFSSSELKQLLCGEQHIQWSLIELQNYTEPTQGYISTSKSYQYFLEVLLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVNTCMHYLKLPEYETKSELKLKLLEACNQIGFYLN 1217
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Planmine SMEST
Match: SMESG000022345.1 (SMESG000022345.1)

HSP 1 Score: 1464.9 bits (3791), Expect = 0.000e+0
Identity = 791/794 (99.62%), Postives = 793/794 (99.87%), Query Frame = 3 
Query: 1119 DDTTIQNTNNKVGLSKVIIDLILCIIRGSHQFLHNLLVKSKLVDIILEITWQYDSSSISILQLIEGMFDQIMERTTYKSNENIQRYKLSTALGMRVIHNRMYSEEMIQQYWNYHEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINNQTMDFYVKDVEGITVTERLEQFIKLNSNPNKIEEINDFILKIENQKLNVKTDIILTKQXXXXXXXXXXXXXXXXNYKPTLRYHVLELLGKIFQSFSHRDHETFISEIYQENSLPYHLSKLVYRVFLQDSGENILEAMKCCLYLTSDNEYSNSYLMWFNRMGIKDILQTAMSKLNIKDQFDYLLKENDERIIPLTYNIEFSENKNVLKTQAYSLNLHQPYYWGDWNIFKTDDGLNLYNEYCYIFISTEESVKNLRCSILTRKTFVDELLSKGSSKDFVKNQLFESLNKTGYWKNLSEDHFNKEPNIRKSQENETDLKSDYVAVEINDKNIYHKKDLIPILLEKYSAILLSMRPVTLPIQFPKLPTGKAINLNHLIISSFTNQLKISCKYNKDENLKIDXXXXXXXXXXXXXXXXXQCFIEISINSIAGVIMKFQNQILYKSGPLNKQAGLKRLGLXXXXXXXXXXXXXXXXXXXXXXXXICFRINSKFQLFNSQLESVDKLNGLFGKTVSKLLSVLESKKCQKKEVVKYITTLDSIISSEEENPTPYELYKSKFIKVLEILFQKYSDDFLDDLLVIIYNNLPKITKILIQLTEQV 3500
            +DTTIQNTNNKVGLSKVIIDLILCIIRGSHQFLHNLLVKSKLVDIILEITWQYDSSSISILQLIEGMFDQIMERTTYKSNENIQRYKLSTALGMRVIHNRMYSEEMIQQYWNYHEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINNQTMDFYVKDVEGITVTERLEQFIKLNSNPNKIEEINDFILKIENQKLNVKTDIILTKQFFIKRIIPILIKIYFKNYKPTLRYHVLELLGKIFQSFSHRDHETFISEIYQENSLPYHLSKLVYRVFLQDSGENILEAMKCCLYLTSDNEYSNSYLMWFNRMGIKDILQTAMSKLNIKDQFDYLLKENDERIIPLTYNIEFSENKNVLKTQAYSLNLHQPYYWGDWNIFKTDDGLNLYNEYCYIFISTEESVKNLRCSILTRKTFVDELLSKGSSKDFVKNQLFESLNKTGYWKNLSEDHFNKEPNIRKSQENETDLKSDYVAVEINDKNIYHKKDLIPILLEKYSAILLSMRPVTLPIQFPKLPTGKAINLNHLIISSFTNQLKISCKYNKDENLKIDEKNENNTEITEIPNVNEQCFIEISINSIAGVIMKFQNQILYKSGPLNKQAGLKRLGLSNSSYESSGSSKDLK PKNLLKDSICFRINSKFQLFNSQLESVDKLNGLFGKTVSKLLSVLESKKCQKKEVVKYITTLDSIISSEEENPTPYELYKSKFIKVLEILFQKYSDDFLDDLLVIIYNNLPKITKILIQLTEQ+
Sbjct:  256 NDTTIQNTNNKVGLSKVIIDLILCIIRGSHQFLHNLLVKSKLVDIILEITWQYDSSSISILQLIEGMFDQIMERTTYKSNENIQRYKLSTALGMRVIHNRMYSEEMIQQYWNYHEHLLKAIVNGNVDHLKELLLSTDFDPNFKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHISVIKALINNQTMDFYVKDVEGITVTERLEQFIKLNSNPNKIEEINDFILKIENQKLNVKTDIILTKQFFIKRIIPILIKIYFKNYKPTLRYHVLELLGKIFQSFSHRDHETFISEIYQENSLPYHLSKLVYRVFLQDSGENILEAMKCCLYLTSDNEYSNSYLMWFNRMGIKDILQTAMSKLNIKDQFDYLLKENDERIIPLTYNIEFSENKNVLKTQAYSLNLHQPYYWGDWNIFKTDDGLNLYNEYCYIFISTEESVKNLRCSILTRKTFVDELLSKGSSKDFVKNQLFESLNKTGYWKNLSEDHFNKEPNIRKSQENETDLKSDYVAVEINDKNIYHKKDLIPILLEKYSAILLSMRPVTLPIQFPKLPTGKAINLNHLIISSFTNQLKISCKYNKDENLKIDEKNENNTEITEIPNVNEQCFIEISINSIAGVIMKFQNQILYKSGPLNKQAGLKRLGLSNSSYESSGSSKDLKSPKNLLKDSICFRINSKFQLFNSQLESVDKLNGLFGKTVSKLLSVLESKKCQKKEVVKYITTLDSIISSEEENPTPYELYKSKFIKVLEILFQKYSDDFLDDLLVIIYNNLPKITKILIQLTEQI 1049

HSP 2 Score: 497.664 bits (1280), Expect = 4.502e-147
Identity = 259/279 (92.83%), Postives = 262/279 (93.91%), Query Frame = 2 
Query:   95 MDDVESPYILLNWLQSGSEEMXXXXXXXXXXXXXXYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPS*FCTENASTSFTCRNFIYKL*SC 931
            MDDVESPYILLNWLQSGSEEMQLSALEQLCLALLQYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNP+    +N +        I  L  C
Sbjct:    1 MDDVESPYILLNWLQSGSEEMQLSALEQLCLALLQYESNETLIKFYPPSTYIPILACLCQDFDISFVLLEAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLTQQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYILYKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDKKISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPNDTTIQNTNNKVGLSKVIIDLILC 279

HSP 3 Score: 300.827 bits (769), Expect = 3.742e-106
Identity = 180/181 (99.45%), Postives = 181/181 (100.00%), Query Frame = 1 
Query: 3499 YRAEKRSFNSFKELLSDPYYVNIPYNDGNHQKGVFHWLATNGFHSDLFMNPLKLDLISVMISEXXXXXXXXXXXXXTVANNTLKEKNLFNKNYVSVRGQNCFLTIQLKPPLGLIPTHYKLACPXXXXXXXXXXXXXXXXXXIDGLEWDTLSTHINDSSALQSNTSWFVWTLEIDSSILEKV 4041
            YRAEKRSFNSFKELLSDPYYVNIPYNDGNHQKGVFHWLATNGFHSDLFMNPLKLDLISVMISENSSSLLNSFNNLFTVANNTLKEKNLFNKNYVSVRGQNCFLTIQLKPPLGLIPTHYKLACPSSAELNSSNLLNWKLLASIDGLEWDTLSTHINDSSALQSNTSWFVWTLEIDSSILEK+
Sbjct: 1124 YRAEKRSFNSFKELLSDPYYVNIPYNDGNHQKGVFHWLATNGFHSDLFMNPLKLDLISVMISENSSSLLNSFNNLFTVANNTLKEKNLFNKNYVSVRGQNCFLTIQLKPPLGLIPTHYKLACPSSAELNSSNLLNWKLLASIDGLEWDTLSTHINDSSALQSNTSWFVWTLEIDSSILEKI 1304

HSP 4 Score: 107.457 bits (267), Expect = 3.742e-106
Identity = 52/52 (100.00%), Postives = 52/52 (100.00%), Query Frame = 2 
Query: 4088 ILVKMNRSQLQTKKIYVIIGIVLPQFLFQVGYLSVPLNSTGRFTQSPRTSRK 4243
            ILVKMNRSQLQTKKIYVIIGIVLPQFLFQVGYLSVPLNSTGRFTQSPRTSRK
Sbjct: 1304 ILVKMNRSQLQTKKIYVIIGIVLPQFLFQVGYLSVPLNSTGRFTQSPRTSRK 1355
The following BLAST results are available for this feature:
BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HECTD12.347e-7632.52HECT domain E3 ubiquitin protein ligase 1 [Source:... [more]
HECTD16.003e-7632.57HECT domain E3 ubiquitin protein ligase 1 [Source:... [more]
HECTD18.907e-7632.57HECT domain E3 ubiquitin protein ligase 1 [Source:... [more]
HECTD18.907e-7632.57HECT domain E3 ubiquitin protein ligase 1 [Source:... [more]
TRIP121.043e-4628.33thyroid hormone receptor interactor 12 [Source:HGN... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hecd-11.027e-7835.55E3 ubiquitin-protein ligase hecd-1 [Source:UniPro... [more]
hecd-11.035e-7835.55E3 ubiquitin-protein ligase hecd-1 [Source:UniPro... [more]
hecd-11.035e-7835.55E3 ubiquitin-protein ligase hecd-1 [Source:UniPro... [more]
hecd-11.255e-7835.55E3 ubiquitin-protein ligase hecd-1 [Source:UniPro... [more]
hecd-11.308e-7835.55E3 ubiquitin-protein ligase hecd-1 [Source:UniPro... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ufd41.459e-7129.93gene:FBgn0032208 transcript:FBtr0080074[more]
ctrip3.881e-3529.59gene:FBgn0260794 transcript:FBtr0334902[more]
ctrip3.881e-3529.59gene:FBgn0260794 transcript:FBtr0303917[more]
ctrip3.881e-3529.59gene:FBgn0260794 transcript:FBtr0303912[more]
ctrip3.954e-3529.59gene:FBgn0260794 transcript:FBtr0344029[more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hectd12.701e-7933.06HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
hectd13.073e-7933.06HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
hectd13.073e-7933.06HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
hectd13.213e-7933.06HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
trip121.031e-4728.52thyroid hormone receptor interactor 12 [Source:NCB... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fbl1.046e-7232.31fibrillarin [Source:Xenbase;Acc:XB-GENE-970225][more]
fbl1.320e-7232.31fibrillarin [Source:Xenbase;Acc:XB-GENE-970225][more]
fbl1.325e-7232.31fibrillarin [Source:Xenbase;Acc:XB-GENE-970225][more]
fbl1.329e-7232.31fibrillarin [Source:Xenbase;Acc:XB-GENE-970225][more]
fbl1.623e-7232.31fibrillarin [Source:Xenbase;Acc:XB-GENE-970225][more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hectd14.958e-7732.58HECT domain E3 ubiquitin protein ligase 1 [Source:... [more]
Hectd11.747e-7632.58HECT domain E3 ubiquitin protein ligase 1 [Source:... [more]
Trip128.063e-4828.33thyroid hormone receptor interactor 12 [Source:MGI... [more]
Trip128.157e-4628.33thyroid hormone receptor interactor 12 [Source:MGI... [more]
Trip128.157e-4628.33thyroid hormone receptor interactor 12 [Source:MGI... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|V6CLA2|HECD1_CAEEL1.664e-7735.55E3 ubiquitin-protein ligase hecd-1 OS=Caenorhabdit... [more]
sp|Q69ZR2|HECD1_MOUSE1.222e-7532.58E3 ubiquitin-protein ligase HECTD1 OS=Mus musculus... [more]
sp|Q9ULT8|HECD1_HUMAN4.032e-7532.57E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens... [more]
sp|Q9VL06|UFD4_DROME1.462e-7029.93E3 ubiquitin-protein ligase Ufd4 OS=Drosophila mel... [more]
sp|Q9LYZ7|UPL4_ARATH4.360e-5529.29E3 ubiquitin-protein ligase UPL4 OS=Arabidopsis th... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0G2YFJ94.934e-17098.47Uncharacterized protein (Fragment) OS=Schmidtea me... [more]
G4VA253.964e-9038.21Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A5K3EG174.062e-8439.53Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A553QVV23.954e-8029.61Uncharacterized protein OS=Danionella translucida ... [more]
A0A4U5MLD95.895e-8036.93Uncharacterized protein OS=Steinernema carpocapsae... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hectd11.708e-7833.55HECT domain containing 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
trip124.719e-4929.09thyroid hormone receptor interactor 12 [Source:NCB... [more]
wwp24.205e-1725.31WW domain containing E3 ubiquitin protein ligase 2... [more]
itchb6.952e-1532.03E3 ubiquitin-protein ligase Itchy [Source:NCBI gen... [more]
itchb1.370e-1430.97E3 ubiquitin-protein ligase Itchy [Source:NCBI gen... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wwp28.473e-1626.25WW domain containing E3 ubiquitin protein ligase 2... [more]
ube3c2.044e-1228.00ubiquitin protein ligase E3C [Source:ZFIN;Acc:ZDB-... [more]
ube3a6.183e-1229.22ubiquitin protein ligase E3A [Source:ZFIN;Acc:ZDB-... [more]
ENSPMAT00000007716.19.893e-1237.61pep scaffold:Pmarinus_7.0:GL480432:8:26910:-1 gene... [more]
nedd4a2.161e-1024.18NEDD4 E3 ubiquitin protein ligase a [Source:ZFIN;A... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
UFD48.608e-4527.48Ubiquitin-protein ligase (E3); interacts with Rpt4... [more]
HUL47.781e-1521.00Protein with similarity to hect domain E3 ubiquiti... [more]
RSP51.069e-1124.43NEDD4 family E3 ubiquitin ligase; regulates proces... [more]
HUL51.755e-928.86Multiubiquitin chain assembly factor (E4); proteas... [more]
TOM15.876e-925.00E3 ubiquitin ligase of the hect-domain class; has ... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO350373.664e-5429.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412126.559e-1827.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO302681.170e-1432.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO344732.959e-1431.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO493277.672e-1428.85Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hectd12.233e-7831.75HECT domain E3 ubiquitin protein ligase 1 [Source:... [more]
trip124.750e-4728.33thyroid hormone receptor interactor 12 [Source:NCB... [more]
trip127.207e-4728.33thyroid hormone receptor interactor 12 [Source:NCB... [more]
hectd13.547e-4236.55HECT domain E3 ubiquitin protein ligase 1 [Source:... [more]
hectd13.808e-4236.71HECT domain E3 ubiquitin protein ligase 1 [Source:... [more]
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BLAST of E3 ubiquitin-protein ligase HECTD1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000022351.10.000e+099.73SMESG000022351.1[more]
SMESG000022351.10.000e+099.73SMESG000022351.1[more]
SMESG000022351.10.000e+099.73SMESG000022351.1[more]
SMESG000022351.10.000e+099.73SMESG000022351.1[more]
SMESG000022345.14.502e-14799.62SMESG000022345.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006114 ID=SMED30006114|Name=E3 ubiquitin-protein ligase HECTD1|organism=Schmidtea mediterranea sexual|type=transcript|length=8332bp
CGATCTCGGAAAAATAATTTTAAATTTAATTTTAAAGTTTTATTGGTTCT
TTGTTAAATTTTTCTTTTCTTACTTTACTTATCTATTAATTAAAATGGAC
GATGTCGAGTCACCATATATTTTACTAAATTGGCTTCAAAGTGGATCAGA
AGAAATGCAGCTTTCTGCACTCGAACAACTATGTTTGGCATTGCTTCAAT
ATGAAAGCAATGAAACTTTAATTAAATTTTATCCTCCATCTACATATATT
CCAATACTGGCTTGTTTGTGCCAAGATTTTGACATTTCATTCGTATTATT
AGAAGCAATTATCAGAACAATGACGTATTACATGCAAGCATTGCCTCACG
AAGTTATTAATCGATTGGTTAATACTAAAGGTTCGTTAGTGGCGATTTGT
ATGAGATTAGAAAATCCAAATATGACCAATCCTGTAGAAAGTGATTTAAC
TCAACAAATTATTAAGCTACTTGAAGAGCTATGCAAGCGCGATACAAAAT
CATTGGCTAATATTGGTGGTACCTCATATGTTATCAGTTTCATGTCTAGA
ACCTATCAAATAATACACCTGGACACCATTAAATCTGGATTTTATATTTT
GTATAAAATAATAGATAAAATAGATCCATCAGACTGTAGATTAGCAGAAT
GGTTTGAGTTTCTCTCAAACTTTTTCAAGCATTCCGATTTTAAAATTGTC
GAGTACAGTCTCCACTGTCTTTTATCCATTGTGAAAGCATGTAATGATAA
AAAAATCTCCACAGATCATCTAGGAATTGAAAAAATCATAGATGATTTAT
TAGAAATGACAATGGTACAGTTGAAAATGGATAACCAAACTAGTCATAAT
CAAAATCCAAGTTAATTTTGCACAGAAAACGCGTCTACTTCCTTCACCTG
TAGGAATTTTATTTATAAATTGTAGTCCTGTTAGTTTCATTGAGACGTAC
ATAAATACGAGGAAGTTGGATAAATACGGTCTACGACTGTTGTTCAATAT
TTTTTGTGTGAAATGGTTTACGATATTTTCAAAATATTATCAAAATACAT
TTCAGAATGCCTGAGAAAGTATCGAAAACTTGTTACTAATTATGCTCATT
ATTTGCAATATTTTATTAGACGATACTACAATCCAAAATACAAACAATAA
AGTCGGTCTATCCAAAGTAATAATAGATTTAATTTTGTGTATAATCCGAG
GCTCCCATCAATTTCTCCATAATTTGTTAGTGAAAAGCAAATTGGTAGAT
ATAATTCTTGAAATCACCTGGCAGTATGATAGTTCCTCCATCAGTATTTT
GCAATTAATTGAAGGTATGTTTGATCAAATTATGGAAAGAACAACTTACA
AGTCGAATGAAAATATTCAAAGATATAAATTGTCAACAGCTTTGGGTATG
AGAGTTATACACAATAGAATGTACAGTGAAGAAATGATTCAGCAATATTG
GAATTACCACGAGCATCTTTTAAAAGCAATAGTAAATGGTAATGTAGATC
ATCTCAAAGAACTTTTGCTTTCAACTGATTTTGATCCCAATTTTAAAGAC
ATTTTTGGTCAGACATCTCTCAATTGGGCTTCAGCAATCGGACTTCTAGA
AGCAGTAAATTTACTATTAACCAGAGGAATAGACCCTAATTTGGGAGAAA
GAGGTACATCATTGCACTATGCTGCTGCTCAAGGACATATAAGTGTTATC
AAGGCTTTAATAAATAATCAAACGATGGATTTTTATGTAAAAGATGTCGA
AGGAATTACTGTTACAGAAAGACTTGAACAGTTTATAAAATTAAATTCTA
ATCCTAACAAAATAGAAGAAATCAATGATTTTATTCTAAAAATAGAAAAC
CAAAAACTCAATGTCAAGACTGATATAATTTTGACAAAACAATTTTTTAT
TAAAAGAATTATTCCAATATTAATAAAGATTTATTTCAAAAATTACAAAC
CCACTTTAAGGTATCATGTTCTTGAACTTTTAGGAAAAATCTTTCAAAGT
TTCTCTCATCGCGATCACGAAACATTTATTTCTGAAATATACCAGGAAAA
CAGTTTGCCATATCATTTATCAAAGTTGGTTTATCGAGTTTTTCTGCAAG
ATTCTGGTGAAAACATATTGGAAGCTATGAAATGCTGTTTATATTTGACT
AGTGACAATGAATACTCTAATTCATATTTAATGTGGTTTAATAGAATGGG
AATTAAAGATATACTACAAACTGCTATGTCGAAATTAAACATTAAGGATC
AATTTGATTACCTATTGAAGGAAAATGATGAAAGGATCATCCCACTAACT
TACAATATTGAGTTTTCAGAAAATAAAAATGTACTAAAAACACAGGCATA
CTCTTTAAATTTGCACCAACCATATTATTGGGGAGATTGGAACATATTCA
AAACAGACGATGGGCTGAATTTATATAATGAATATTGCTACATTTTCATA
TCAACCGAAGAATCTGTTAAAAATCTAAGATGCTCTATTTTAACTCGTAA
AACATTTGTTGATGAACTTCTAAGTAAAGGAAGTTCAAAAGATTTCGTGA
AAAACCAACTTTTTGAAAGCTTGAATAAAACTGGATATTGGAAAAATTTA
TCCGAAGACCATTTTAATAAAGAACCAAATATAAGAAAAAGCCAAGAAAA
CGAAACAGATTTAAAATCAGATTATGTTGCTGTTGAAATTAATGACAAAA
ATATTTATCATAAAAAAGATTTGATTCCAATATTATTAGAGAAATACAGT
GCCATTCTTCTTTCGATGAGACCAGTAACCTTGCCAATACAATTTCCGAA
ATTACCTACGGGCAAAGCCATAAATTTAAATCATTTAATTATTTCCAGTT
TCACTAACCAATTAAAAATTAGTTGTAAATATAATAAAGATGAAAATTTA
AAGATCGACGAAAAAAATGAAAACAACACAGAAATAACAGAAATTCCAAA
TGTCAACGAGCAATGTTTTATAGAAATATCAATAAACAGCATTGCCGGAG
TCATCATGAAGTTTCAGAATCAAATTCTATATAAAAGTGGACCCCTGAAT
AAACAAGCCGGATTAAAAAGATTAGGATTATCAAACTCTAGTTATGAAAG
TTCTGGTTCTTCCAAAGATCTAAAGCCGCCAAAAAATCTCCTAAAAGATT
CAATTTGCTTTCGAATAAATTCCAAATTTCAACTATTTAATAGTCAACTT
GAATCCGTGGATAAATTAAATGGGCTATTCGGAAAGACTGTATCTAAGTT
ATTAAGTGTTCTTGAAAGTAAGAAGTGTCAGAAAAAGGAAGTAGTGAAAT
ATATAACTACATTGGACAGCATTATTTCATCCGAGGAAGAAAATCCAACT
CCGTATGAGCTATACAAATCCAAATTTATTAAAGTATTAGAAATTCTATT
TCAGAAATATTCTGATGATTTCCTTGATGATCTATTGGTTATTATTTATA
ATAATTTACCTAAAATAACTAAGATATTAATCCAGTTGACTGAGCAAGTA
TAGAGCAGAAAAACGGTCATTTAATTCTTTCAAAGAGTTGCTATCTGATC
CATATTATGTAAATATTCCTTACAATGATGGAAATCACCAGAAAGGGGTT
TTCCATTGGTTAGCAACAAATGGGTTCCATTCCGATTTGTTTATGAATCC
GTTGAAATTAGATTTAATAAGCGTTATGATTTCCGAAAATTCCAGTAGCT
TGTTAAATTCCTTTAACAATTTATTCACAGTTGCAAATAATACATTGAAA
GAAAAGAATTTATTTAACAAAAACTATGTGTCCGTGCGTGGACAAAATTG
TTTTCTTACAATCCAATTGAAGCCCCCTCTAGGACTGATACCAACTCATT
ACAAATTGGCTTGTCCGAGTTCTGCAGAATTAAATTCTTCAAATTTATTA
AATTGGAAATTATTGGCATCAATTGATGGATTAGAATGGGATACACTCTC
GACCCACATAAATGATAGCAGTGCCTTACAGTCAAATACATCATGGTTCG
TTTGGACATTAGAAATAGATTCATCAATATTGGAAAAGGTGAAAAATCAC
GGTTGGACACTGTTTAAGATTCAGCACTTAAATCTAGATCCTAGTAAAAA
TGAACAGATCACAATTGCAGACCAAAAAAATTTATGTAATAATTGGCATA
GTTCTTCCTCAATTCCTGTTTCAAGTGGGTTATCTATCAGTTCCATTGAA
TTCTACGGGACGGTTTACTCAATCTCCGAGGACAAGCAGAAAGAAATTAA
AGATCAAATAGACATTCACCTTTCCAAATTCAAATTAAAATCTCTAGTTC
TGCCGGGACCCGATTGGGTTTTTGATAATCGAGAAAGTTATAAAATAGGA
AAAACATTAACTCTCATAAAAAACGGAACGGTTCTCGTCGAATGGCTACG
TGATTCTGAAAAATGTCACATCCGCCATAAAATGGGCTCCCAAGGAAAAT
ATGAAATCTTATTAGCTTCACAAGAACAAATAGAAGCATTAAATGATAAA
AACGACGTGATAAAAAATAATTTAACAGATTCAATAATAGAAAGCAGATC
TTCAAATGAATTCCATCAAGTTTCCCATGAAAATTTTAGACATTCATTTC
AAGATTCAATTTCATGGATAATTGATCCGAATATTTCGATGCCTTTAAGA
ACTTCTAGCTTATCAAGTCAGAGAAATTCCCGATTACCATCTATTTCCAA
CAAAGATAATTGGATGGATAAAGAAATTAGTCGCGATTTTAATAATTTTC
AAGAATCGCTTGATGATAACCGAGATAACCATATAATCGTGCAGTCTGAA
ACAGAGGATTTTGATCTTCAATATGAAAATAGTGAATTTGAACTGACGAA
TGTTGATATTAACAATAGGAAAGCCGATTTAATTAAGAAAGATGATCGAG
ATATAACAGCAAACGGTAAATCATTATTTCAAATGAAAGATACAATCACA
GTAAAAAATAATGACACAAATCAATTGAAAAATCAACAGTTTTCTAAATC
AATTGATGATTTTAAGAAAAGTTTCAGTATGAATAAACAAACTAAACGGA
AATCCCACCAGATTGTAAACATGTTGACGGATAGTAAAAATGAAATTTTA
AAAAAAGATATTATAAAATTCAACACTTTAACGGAAGATATTGAAATGAG
TGATCAAAGTGAAGAATACGAAGTTTTGCAATGCCCTGAAAATTTCTTGA
AACGCAAAAAAAACTATTTGGAAAATAGTGAAATCACTCAAAATAAGCCA
AGTGCCAAAAGAAAGCCTTACAATCCGTTTGGGAAGAATAACAAATTTAA
ACAAACTATTACCAGCAAAAATGAAACAAACATGAAATTTAAACCAATTT
CAATTGAACAGCCCTTTCCTGGTCTTGTTCAAGCAATAGATCATAGATCT
ACATCGGCTCTCACTCAAATTCTTTCAAACGTTGAAAATCTGAATTACAG
ACCAAATAAAAAGTTTTCAAAACCGGATGAAACAACTAAAATCAAAAAAT
TCGGATACGATTCAGATCAATTCCGTTTAAAATTTCAAATTCAGAAACTT
CTTCCGGCAAATAGATCACTTTATTGCCAAAAATTCAATGATTTCAAAGC
CTCCAATTTCGATTGGCTGAATTCTGACCTCCAATTGGAAAATCATGAAA
CCGATCAGAAAACCTATGAATTTATTTTGAAATCTGATTCCACTTTTCCA
ATTGCAAATTATGTTTTAAAAATGCTGCCATCGCCTGATCCGATTTTAAA
CATTTATCCCATTGACAATGTATCAGAAATTTGGCATAGTCAATTTACGT
TATTTTACGGATTCTGTGACAAAAAAGGACCTGGGACATCGTGTCAAAAT
TGTTTTTATCAAAAAATCAAAACGTCCAACGAGGCTACTGATAAAAACAA
AAAGCCTGCTAATGAGATTGATAAAATATTTTCAATTTTACATCATTTAA
AATGTTCACAATTGAGATTCATAGAAAAAACAAAAAATCAAGTGATGAAA
TTACAATATTTAGATGTGGATTGGCTAGATTTATATTTCATCTCACAACA
TATGTGCAAGAAGGTTTTGTCTCAGCTTGAGGATGTTTGGAGTTTGATTT
CTCGAGATACGCTGCCTTCTTGGATTGTTGAATGGCCACAGAAATATCCA
TTTGTCTTTTTCTATGATGTTAAAATTGACATATTGAAAGCCTTCTGGTT
TGGAGTTTCGAGATCAGTAATTTGGCTTCAACAACGAGCAAAACCAAATA
GTGATTTTATTCGGCCGTCATTTAGAGATGATCTTGTGGCCCCATTTCAT
TTTCTAGGCAGGCTTAAGAAACATATAGCTCAAATTCCTCGGCCGTATTA
TTTCGGAAACACAATTTTAACTGAAGCTGAATCACGATCTATATTTTGGT
CAGCAGTTCGAGATTTGCTAGTATTCCATGCAAAATCAAAAGAGGAGCTA
GAAATTCAATTCGATCAAGAAGAAGGAACAGGTCTTGGACCAACATTAGA
ATTTATTAATATTCTAAGCAAAGAATTTATGAGACCGAGCCTTTTAATGT
GGGTCCATACTGACTCGTTTTTGGAAGAAGAGAATGAATTTGTTTTTTCC
AAAAATGGATTATTTCCTTATCCTTGGCCTGCAGATAAATTAACAGAGGA
ACTTCTTGAAAAATTCAGATTGCTTGGAATATTTATGGCTAAATCTTTAC
AAGATAATCGAATCATGGATCTTCCATTTTCTGAGTTGTTTCTAGAAATT
CTTTGCAAAGATTTTTCTGATTATAATAAAAAAGAATATTTAAAAAGATT
TATGCTGATTTATCCCGAAAGAGGATTATTTCTCATGTCCATTGAATTAT
TTTGTGAAGAAAAGCAAAAACTTTTAAAAACTATTAATGAAGCTGGAAAT
CGAACTTTATGGAAAGTTCATGATCAACTAAAATGTCTCGCAATTGAAAT
TTTCGGAACCACCTTCGATGGATTATGTTTAGACATGGAATTTCTTCCCA
CCTCAAAAATATATGGAACAGTTCCATTTCCTTTATATGATCATTATTGG
TGGGAAGATGATAGTGATTCTCACGACGATATTTGTAACATGGGATATGA
AAAAGATTCTTTTCACGAACCAGTTACCGAAAACAATGCTGAAAATTATC
TCCAAAGAACTTTGAATTTCGCTATGAATAAAGGAATAAAAAAACAGTTT
GCACAAATTATAGATGGCTTTAATGAAGTCTTTCCAATAAAAAGTCTTTC
GATGTTTTCATCCAGTGAGCTAAAACAACTGCTATGCGGTGAACAGCACA
TTAAGTGGTCACTGATAGAACTTCAAAATTATACTGAGCCTACTCAAGGC
TACATATCAACATCAAAAAGCTATCAATATTTTCTGGAAGTTCTGTTGGA
ATTGAATCAAATCGAACGGAAAATGTTTGTGCAATTCATTTCGGGTTGTT
CAAGTTTGCCCCCGGGTGGATTAAAAAATCTAAAACCCCGTTTAACAATC
GTTAAGAAAAATGTCAAAGACGGCCCCTATCCGAGCGTCAACACTTGCAT
GCATTATTTGAAACTGCCGGAATACGAGACTAAGTCAGAACTGAAATTGA
AACTATTGGAAGCATGTAACCAAATCGGATTTTATTTAAATTGAATTCGA
TCGAAAATTCTAAATCAATTGGTTGACATTTAATTCATTTTCTGTGAGAG
AAATTAGCAATCCGCTGAACTTTACGATTTCAATTCTCATTCAATTACTG
CCGGTAGATTGCTATCGAACTGATTTTCTAGAAATTGTTTGCTTTTCTTA
TTAGTCAATTTCTTTAATGTATCACTCGTCAACACAAGCTTTGGAACAGT
GATATTTATAATTTTTTGGAATTTCTTAATACTAAATGTGGAAGATACTC
ATAGTACACTGGAAATATTTTCAAGATGATTATGGGGCGTCACATTGTAC
CAATCTGTGATCTTATTTCCTTCAGCATTATTCATACATCAGACTTTGGG
GCGTCCTGGTTTTAGCTAGCTAGTTGGCACATCTATTTAAAGGATCTCTA
ACTATTGGACATATCTTCTTATTGCTGTGAATTGTTTTCATTCGGTGGGA
GCAAGGCATTTAGGTCAATCGCTAATCTGGAAATTTACTTGGGTCCAAAT
TGTCCTCGTTTCAGGAGCTATTCGTGTGCGATGGTGAAGATGTATGGGGG
AATTATTCTACCATTTTTCTTCTGAGTAAATTAACCACGGTCAAAATATT
CATGAAAACTATTATTCAATCATATCTCGGATTCGGAATGCGCTTTTTTT
ATTTGAAAATCATGAGATGGTCCTCCTGTCTC
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protein sequence of SMED30006114-orf-1

>SMED30006114-orf-1 ID=SMED30006114-orf-1|Name=SMED30006114-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=804bp
MLIICNILLDDTTIQNTNNKVGLSKVIIDLILCIIRGSHQFLHNLLVKSK
LVDIILEITWQYDSSSISILQLIEGMFDQIMERTTYKSNENIQRYKLSTA
LGMRVIHNRMYSEEMIQQYWNYHEHLLKAIVNGNVDHLKELLLSTDFDPN
FKDIFGQTSLNWASAIGLLEAVNLLLTRGIDPNLGERGTSLHYAAAQGHI
SVIKALINNQTMDFYVKDVEGITVTERLEQFIKLNSNPNKIEEINDFILK
IENQKLNVKTDIILTKQFFIKRIIPILIKIYFKNYKPTLRYHVLELLGKI
FQSFSHRDHETFISEIYQENSLPYHLSKLVYRVFLQDSGENILEAMKCCL
YLTSDNEYSNSYLMWFNRMGIKDILQTAMSKLNIKDQFDYLLKENDERII
PLTYNIEFSENKNVLKTQAYSLNLHQPYYWGDWNIFKTDDGLNLYNEYCY
IFISTEESVKNLRCSILTRKTFVDELLSKGSSKDFVKNQLFESLNKTGYW
KNLSEDHFNKEPNIRKSQENETDLKSDYVAVEINDKNIYHKKDLIPILLE
KYSAILLSMRPVTLPIQFPKLPTGKAINLNHLIISSFTNQLKISCKYNKD
ENLKIDEKNENNTEITEIPNVNEQCFIEISINSIAGVIMKFQNQILYKSG
PLNKQAGLKRLGLSNSSYESSGSSKDLKPPKNLLKDSICFRINSKFQLFN
SQLESVDKLNGLFGKTVSKLLSVLESKKCQKKEVVKYITTLDSIISSEEE
NPTPYELYKSKFIKVLEILFQKYSDDFLDDLLVIIYNNLPKITKILIQLT
EQV*
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protein sequence of SMED30006114-orf-2

>SMED30006114-orf-2 ID=SMED30006114-orf-2|Name=SMED30006114-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=288bp
DLGKIILNLILKFYWFFVKFFFSYFTYLLIKMDDVESPYILLNWLQSGSE
EMQLSALEQLCLALLQYESNETLIKFYPPSTYIPILACLCQDFDISFVLL
EAIIRTMTYYMQALPHEVINRLVNTKGSLVAICMRLENPNMTNPVESDLT
QQIIKLLEELCKRDTKSLANIGGTSYVISFMSRTYQIIHLDTIKSGFYIL
YKIIDKIDPSDCRLAEWFEFLSNFFKHSDFKIVEYSLHCLLSIVKACNDK
KISTDHLGIEKIIDDLLEMTMVQLKMDNQTSHNQNPS*
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protein sequence of SMED30006114-orf-3

>SMED30006114-orf-3 ID=SMED30006114-orf-3|Name=SMED30006114-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1334bp
MNPLKLDLISVMISENSSSLLNSFNNLFTVANNTLKEKNLFNKNYVSVRG
QNCFLTIQLKPPLGLIPTHYKLACPSSAELNSSNLLNWKLLASIDGLEWD
TLSTHINDSSALQSNTSWFVWTLEIDSSILEKVKNHGWTLFKIQHLNLDP
SKNEQITIADQKNLCNNWHSSSSIPVSSGLSISSIEFYGTVYSISEDKQK
EIKDQIDIHLSKFKLKSLVLPGPDWVFDNRESYKIGKTLTLIKNGTVLVE
WLRDSEKCHIRHKMGSQGKYEILLASQEQIEALNDKNDVIKNNLTDSIIE
SRSSNEFHQVSHENFRHSFQDSISWIIDPNISMPLRTSSLSSQRNSRLPS
ISNKDNWMDKEISRDFNNFQESLDDNRDNHIIVQSETEDFDLQYENSEFE
LTNVDINNRKADLIKKDDRDITANGKSLFQMKDTITVKNNDTNQLKNQQF
SKSIDDFKKSFSMNKQTKRKSHQIVNMLTDSKNEILKKDIIKFNTLTEDI
EMSDQSEEYEVLQCPENFLKRKKNYLENSEITQNKPSAKRKPYNPFGKNN
KFKQTITSKNETNMKFKPISIEQPFPGLVQAIDHRSTSALTQILSNVENL
NYRPNKKFSKPDETTKIKKFGYDSDQFRLKFQIQKLLPANRSLYCQKFND
FKASNFDWLNSDLQLENHETDQKTYEFILKSDSTFPIANYVLKMLPSPDP
ILNIYPIDNVSEIWHSQFTLFYGFCDKKGPGTSCQNCFYQKIKTSNEATD
KNKKPANEIDKIFSILHHLKCSQLRFIEKTKNQVMKLQYLDVDWLDLYFI
SQHMCKKVLSQLEDVWSLISRDTLPSWIVEWPQKYPFVFFYDVKIDILKA
FWFGVSRSVIWLQQRAKPNSDFIRPSFRDDLVAPFHFLGRLKKHIAQIPR
PYYFGNTILTEAESRSIFWSAVRDLLVFHAKSKEELEIQFDQEEGTGLGP
TLEFINILSKEFMRPSLLMWVHTDSFLEEENEFVFSKNGLFPYPWPADKL
TEELLEKFRLLGIFMAKSLQDNRIMDLPFSELFLEILCKDFSDYNKKEYL
KRFMLIYPERGLFLMSIELFCEEKQKLLKTINEAGNRTLWKVHDQLKCLA
IEIFGTTFDGLCLDMEFLPTSKIYGTVPFPLYDHYWWEDDSDSHDDICNM
GYEKDSFHEPVTENNAENYLQRTLNFAMNKGIKKQFAQIIDGFNEVFPIK
SLSMFSSSELKQLLCGEQHIKWSLIELQNYTEPTQGYISTSKSYQYFLEV
LLELNQIERKMFVQFISGCSSLPPGGLKNLKPRLTIVKKNVKDGPYPSVN
TCMHYLKLPEYETKSELKLKLLEACNQIGFYLN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002056medial muscle cell
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR002110Ankyrin_rpt
IPR020683Ankyrin_rpt-contain_dom
IPR001148CA_dom
IPR011989ARM-like
IPR016024ARM-type_fold
IPR000569HECT_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0005488binding
GO:0004842ubiquitin-protein transferase activity
GO:0016740transferase activity
GO:0016874ligase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0016567protein ubiquitination