SMED30006077

Overview


Name	SMED30006077
Smed ID	SMED30006077
Length (bp)	647

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SMED30006077 (SMED30006077) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30006077 (SMED30006077) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30006077 (SMED30006077) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30006077 (SMED30006077) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30006077

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30006077	h1SMcG0021799	SmedASXL_004728	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
head region	SMED30006077	h1SMcG0021799	SmedASXL_053137	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30006077	h1SMcG0021799	dd_Smed_v4_33012_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30006077	h1SMcG0021799	dd_Smed_v4_33012_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30006077	h1SMcG0021799	dd_Smed_v4_33012_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30006077	h1SMcG0021799	dd_Smed_v6_33012_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of SMED30006077 vs. Ensembl Human
Match: TACR2 (tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527])

HSP 1 Score: 62.003 bits (149), Expect = 7.903e-11
Identity = 39/160 (24.38%), Postives = 76/160 (47.50%), Query Frame = -2

Query:  152 PDLIKGRQIL--YVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNE----AMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQP--VGEQKDRISTISSRYLS 607
            P+   G+ +L  ++++I + YF+P A+M  AY  I   LW+  +P      A +  +Q  KK    +V +++TF +CW P  +  ++  F   I   +  + +      +   + ++ P +Y   N +F+  FR  F C P     ++D++    +  LS
Sbjct:  150 PEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLS 309

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BLAST of SMED30006077 vs. Ensembl Human
Match: TACR2 (tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527])

HSP 1 Score: 62.003 bits (149), Expect = 8.187e-11
Identity = 39/160 (24.38%), Postives = 76/160 (47.50%), Query Frame = -2

Query:  152 PDLIKGRQIL--YVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNE----AMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQP--VGEQKDRISTISSRYLS 607
            P+   G+ +L  ++++I + YF+P A+M  AY  I   LW+  +P      A +  +Q  KK    +V +++TF +CW P  +  ++  F   I   +  + +      +   + ++ P +Y   N +F+  FR  F C P     ++D++    +  LS
Sbjct:  186 PEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLS 345

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BLAST of SMED30006077 vs. Ensembl Human
Match: HCRTR2 (hypocretin receptor 2 [Source:HGNC Symbol;Acc:HGNC:4849])

HSP 1 Score: 60.8474 bits (146), Expect = 1.994e-10
Identity = 46/195 (23.59%), Postives = 90/195 (46.15%), Query Frame = -2

Query:  119 QILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPN--------------------------------EAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVD-VFGWRITQTQNHRTI---IFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVG---EQKDRISTISSRYLSDNQKTLGTEIS 586
            ++ ++   +V Y  P  +M  AY+ I  KLW   +P                                  A I +I+ R+K   ML+ +L+ F +C+ P+ ++N++  VFG     T++  T+      ++ + + N+   P +Y   + KF++ F+  F C  +G    Q+DR++    R  ++++K+L T+IS
Sbjct:  221 KMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFG-MFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLT--RGRTSTESRKSLTTQIS 412

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Query:  119 QILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPN--------------------------------EAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVD-VFGWRITQTQNHRTI---IFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVG---EQKDRISTISSRYLSDNQKTLGTEIS 586
            ++ ++   +V Y  P  +M  AY+ I  KLW   +P                                  A I +I+ R+K   ML+ +L+ F +C+ P+ ++N++  VFG     T++  T+      ++ + + N+   P +Y   + KF++ F+  F C  +G    Q+DR++    R  ++++K+L T+IS
Sbjct:  221 KMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFG-MFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLT--RGRTSTESRKSLTTQIS 412

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BLAST of SMED30006077 vs. Ensembl Human
Match: TACR3 (tachykinin receptor 3 [Source:HGNC Symbol;Acc:HGNC:11528])

HSP 1 Score: 58.151 bits (139), Expect = 2.196e-9
Identity = 37/177 (20.90%), Postives = 82/177 (46.33%), Query Frame = -2

Query:   92 PDLIKGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMI---ARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPV--GEQKDRISTISSRYLSDNQKTLGTEISLAPLTRMTS 607
            P+  K     ++I+II+ Y  P  IM   Y  +   LW   +P +       +++ ++KV  M++ +++TF +CW P  +  ++     ++ + +  + +   +  +   + ++ P +Y   NK+F+  F+  F   P       D +   ++R+  + Q ++ T      +TRM S
Sbjct:  238 PEGPKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYT------VTRMES 408

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BLAST of SMED30006077 vs. Ensembl Celegans
Match: npr-34 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:G5EDR6])

HSP 1 Score: 58.9214 bits (141), Expect = 3.981e-10
Identity = 36/120 (30.00%), Postives = 60/120 (50.00%), Query Frame = -2

Query:  164 KLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGW--RITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETF-----HCQPVGEQKDRISTISS 502
            K + NH  N    A   ++K++  ML+SI+  + VCW P  V  L+  FG+  R + TQ  + +    NA+ +C +   P LYA  ++ F+  F+  +       Q V E + R+ + SS
Sbjct:  324 KSYSNHRNNRVAEA---NKKQIVQMLISIVCMYTVCWLPTIVDELLTSFGYICRTSNTQTLKHMRMGFNALTYCQSCINPILYAFISQNFRSTFKTAYSRMKSRLQGVEEMRSRMGSCSS 440

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BLAST of SMED30006077 vs. Ensembl Celegans
Match: tkr-3 (TachyKinin Receptor family [Source:UniProtKB/TrEMBL;Acc:Q58AU0])

HSP 1 Score: 52.7582 bits (125), Expect = 3.851e-8
Identity = 27/121 (22.31%), Postives = 56/121 (46.28%), Query Frame = -2

Query:  212 VIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFH 574
            V ++I+ YF+P  I+ +AY  I  K+W        +       +K+   L+ ++  F +CW P++   L++     I   +    + F ++ +   N+   P +Y  +N K+ + +R  F 
Sbjct:  214 VYLVIIQYFVPMIILDTAYTMIAVKIWSLSQSRVELDETKMATQKLMRTLIIVVACFSLCWFPLETYLLLNELKPEINGWKYINLVFFFSHWLAMSNSCLNPIIYGLYNTKYNEEYRRLFR 334

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BLAST of SMED30006077 vs. Ensembl Celegans
Match: nmur-2 (NMUR (NeuroMedin U Receptor) homolog [Source:UniProtKB/TrEMBL;Acc:O17239])

HSP 1 Score: 50.0618 bits (118), Expect = 3.524e-7
Identity = 47/177 (26.55%), Postives = 83/177 (46.89%), Query Frame = -2

Query:  116 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNH--MPNEAMIARIQHR--KKVTTMLVSILITFYVCWTPVQVINLVDVF-GWRITQT-----QNHRTIIFITNAIGFC---NALFYPFLYAGHNKKFKQAFRETFHCQPV------GEQKDRISTISSRYLSDNQKTLGTEISL 589
            ++++ +    VF+ IPA  +   Y  I  +L  +   +  + M+ + +++  + V  ML+S++ITF++CW P  +  L+ V+  W  T T     Q    I+F  +  GFC   N+   P LY   ++K++ AF  T     +      G Q+   S   S      Q+TL T  S+
Sbjct:  215 QKMIIIFAFTVFFVIPAIAIVIMYAHIAVQLESSEIDLKGDKMVKKRRNKSNRTVLKMLLSVVITFFICWLPFHIQRLLSVYTTWSETTTISPPVQFLSMIVFYIS--GFCYYSNSAANPILYNILSQKYRSAFCRTILGDHIANFVFKGHQRPGQSKRCSSSTEAEQRTLMTRGSV 389

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BLAST of SMED30006077 vs. Ensembl Celegans
Match: ser-1 (SERotonin/octopamine receptor family; Serotonin receptor [Source:UniProtKB/TrEMBL;Acc:O17470])

HSP 1 Score: 48.521 bits (114), Expect = 1.556e-6
Identity = 26/84 (30.95%), Postives = 42/84 (50.00%), Query Frame = -2

Query:  206 IQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQ 457
            + +  K T +L  +   F++CWTP   IN +  FG    Q  +    IF+   +G+ ++   P +Y   NK+F+QAF     CQ
Sbjct:  364 LANEHKATRVLAVVFACFFICWTPFFFINFLIGFGGENVQIPDWVASIFL--WLGYVSSTINPIIYTVFNKRFRQAFVRILRCQ 445

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BLAST of SMED30006077 vs. Ensembl Celegans
Match: ser-1 (SERotonin/octopamine receptor family; Serotonin receptor [Source:UniProtKB/TrEMBL;Acc:O17470])

HSP 1 Score: 48.521 bits (114), Expect = 1.588e-6
Identity = 26/84 (30.95%), Postives = 42/84 (50.00%), Query Frame = -2

Query:  206 IQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQ 457
            + +  K T +L  +   F++CWTP   IN +  FG    Q  +    IF+   +G+ ++   P +Y   NK+F+QAF     CQ
Sbjct:  316 LANEHKATRVLAVVFACFFICWTPFFFINFLIGFGGENVQIPDWVASIFL--WLGYVSSTINPIIYTVFNKRFRQAFVRILRCQ 397

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BLAST of SMED30006077 vs. Ensembl Fly
Match: Lkr (gene:FBgn0035610 transcript:FBtr0077149)

HSP 1 Score: 66.6254 bits (161), Expect = 1.225e-12
Identity = 35/122 (28.69%), Postives = 66/122 (54.10%), Query Frame = -2

Query:  215 MIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIAR----IQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETF 568
            ++ V Y +P  +++  YI +  +LW    P  A  +R    ++++KKV  ML+ ++I F +CW P+Q+ N++ V    I        + F  + +   N+ + PF+Y  +N+KFK+ F + F
Sbjct:  212 LVFVQYLVPFCVISFVYIQMAVRLWGTRAPGNAQDSRDITLLKNKKKVIKMLIIVVIIFGLCWLPLQLYNILYVTIPEINDYHFISIVWFCCDWLAMSNSCYNPFIYGIYNEKFKREFNKRF 333

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BLAST of SMED30006077 vs. Ensembl Fly
Match: SIFaR (gene:FBgn0038880 transcript:FBtr0084098)

HSP 1 Score: 56.225 bits (134), Expect = 4.677e-9
Identity = 37/127 (29.13%), Postives = 68/127 (53.54%), Query Frame = -2

Query:  227 LYVIM--IIVFYFIPAAIMTSAYICIICKLWKNHMPNE---AMIARIQHRKKVTT--MLVSILITFYVCWTPVQVINLVDVFGWRITQTQNH--RTIIFITNAIGFCNALFYPFLYAGHNKKFKQAF 580
            LY ++  ++  Y +P +++T  Y+ I  K+    +P E   A + R+Q + KV    MLV+++I F + W P+ VI     FG  I+Q +    + ++ +   +G  N+   P LY+  NKK+++ F
Sbjct:  380 LYFLLANLVACYLLPMSLITLCYVLIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGF 505

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BLAST of SMED30006077 vs. Ensembl Fly
Match: SIFaR (gene:FBgn0038880 transcript:FBtr0301815)

HSP 1 Score: 56.225 bits (134), Expect = 4.677e-9
Identity = 37/127 (29.13%), Postives = 68/127 (53.54%), Query Frame = -2

Query:  227 LYVIM--IIVFYFIPAAIMTSAYICIICKLWKNHMPNE---AMIARIQHRKKVTT--MLVSILITFYVCWTPVQVINLVDVFGWRITQTQNH--RTIIFITNAIGFCNALFYPFLYAGHNKKFKQAF 580
            LY ++  ++  Y +P +++T  Y+ I  K+    +P E   A + R+Q + KV    MLV+++I F + W P+ VI     FG  I+Q +    + ++ +   +G  N+   P LY+  NKK+++ F
Sbjct:  380 LYFLLANLVACYLLPMSLITLCYVLIWIKVSTRSIPGESKDAQMDRMQQKSKVKVIKMLVAVVILFVLSWLPLYVIFARIKFGSDISQEEFEILKKVMPVAQWLGSSNSCINPILYS-VNKKYRRGF 505

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BLAST of SMED30006077 vs. Ensembl Fly
Match: sNPF-R (gene:FBgn0036934 transcript:FBtr0332667)

HSP 1 Score: 53.5286 bits (127), Expect = 3.175e-8
Identity = 31/133 (23.31%), Postives = 64/133 (48.12%), Query Frame = -2

Query:  209 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNH--MPNEAMIARIQ----HRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHC 589
            R++   I   + + +P  I++  Y+ I  KL +     P      R +     +K+   ML++++  F + W P+ V+N+ D F  +  + + +    F+ ++I   +  + PFLYA  N+ F++ F+    C
Sbjct:  278 RKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPC 410

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BLAST of SMED30006077 vs. Ensembl Fly
Match: sNPF-R (gene:FBgn0036934 transcript:FBtr0074871)

HSP 1 Score: 53.5286 bits (127), Expect = 3.175e-8
Identity = 31/133 (23.31%), Postives = 64/133 (48.12%), Query Frame = -2

Query:  209 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNH--MPNEAMIARIQ----HRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHC 589
            R++   I   + + +P  I++  Y+ I  KL +     P      R +     +K+   ML++++  F + W P+ V+N+ D F  +  + + +    F+ ++I   +  + PFLYA  N+ F++ F+    C
Sbjct:  278 RKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPC 410

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BLAST of SMED30006077 vs. Ensembl Zebrafish
Match: npy2rl (neuropeptide Y receptor Y2, like [Source:ZFIN;Acc:ZDB-GENE-111115-4])

HSP 1 Score: 65.855 bits (159), Expect = 2.500e-12
Identity = 39/145 (26.90%), Postives = 68/145 (46.90%), Query Frame = -2

Query:  173 PDLIKGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRIST 607
            PD      +  +  +++ Y +P AI++ AYI I  KL +NH+       R   R+K T MLV++++ F V W P     L       +   ++ R +  + + +  C+    P LY   N+ ++ AF   F C+   E+ D + T
Sbjct:  202 PDSSTDSTLYSISTLLLQYVLPLAIISFAYIRIWSKL-RNHVSPVGRNDRHHRRRKTTKMLVTMVVVFAVSWLPFHAFQLAIDIDHSVLDMKDFRLLYTVFHIVAMCSTFANPLLYGWMNRNYRSAFVAVFRCK---ERLDSLHT 342

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BLAST of SMED30006077 vs. Ensembl Zebrafish
Match: hcrtr2 (hypocretin (orexin) receptor 2 [Source:ZFIN;Acc:ZDB-GENE-070228-3])

HSP 1 Score: 63.1586 bits (152), Expect = 2.399e-11
Identity = 49/209 (23.44%), Postives = 92/209 (44.02%), Query Frame = -2

Query:   92 PDLIKGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMI--------------------------------ARIQHRKKVTTMLVSILITFYVCWTPVQVINLVD-VFGWRITQTQNHRTI---IFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEI-SLAPLTRMTS 607
            PD I  + + +    IV YF P  +M  AYI I  KLW   +P  + +                                 +++ R+K   ML+ +L  F +C+ P+ ++N++  VFG     T N  T+      ++ + + N+   P +Y   + KF++ F+  F CQ  G  +        R  +D++K+L T++ +L  ++R++ 
Sbjct:  215 PDEIYPK-VYHTCFFIVTYFAPLCLMVLAYIQICHKLWCQQIPGSSSVLQRQWKSLQCSAHAVGSGESVKVRTSTVSAEAKQVKARRKTARMLMVVLFVFALCYLPISILNIMKRVFG-AFKNTGNRETVYAWFTFSHWLIYANSAANPIIYNFLSGKFREEFKAAFICQCSGRGETHKQRARGRTSTDSRKSLSTQVNNLDNISRISD 421

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BLAST of SMED30006077 vs. Ensembl Zebrafish
Match: galr2b (galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-131121-48])

HSP 1 Score: 62.3882 bits (150), Expect = 3.602e-11
Identity = 36/157 (22.93%), Postives = 75/157 (47.77%), Query Frame = -2

Query:  119 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEIS 589
            R++L     +  Y IP  I++ +Y   I  LW    P + M    + ++KVT M++ + + F +CW P  V+ L  ++G      Q       +++ + + N+   P +YA  +K F++ F++ F C    + ++++  ++        +   TE+S
Sbjct:  186 RKVLDTCTFVFGYVIPVLIVSLSYTRTIKYLWTAVDPLDGMSESKRAKRKVTKMIIIVTVLFCICWLPYHVVILCYLYG-DFPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCILSKKGRNKVHVVNVANTVPGFEAGSTEVS 341

[Close]

Query:  119 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEIS 589
            R++L     +  Y IP  I++ +Y   I  LW    P + M    + ++KVT M++ + + F +CW P  V+ L  ++G      Q       +++ + + N+   P +YA  +K F++ F++ F C    + ++++  ++        +   TE+S
Sbjct:  186 RKVLDTCTFVFGYVIPVLIVSLSYTRTIKYLWTAVDPLDGMSESKRAKRKVTKMIIIVTVLFCICWLPYHVVILCYLYG-DFPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCILSKKGRNKVHVVNVANTVPGFEAGSTEVS 341

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BLAST of SMED30006077 vs. Ensembl Zebrafish
Match: CABZ01084347.1 (pyroglutamylated RFamide peptide receptor b [Source:NCBI gene;Acc:101886159])

HSP 1 Score: 62.7734 bits (151), Expect = 3.620e-11
Identity = 44/169 (26.04%), Postives = 85/169 (50.30%), Query Frame = -2

Query:  110 RQILYVIMIIVFYFIPAAIMTSAYICIICKLW-KNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRT---IIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHC---QPVGEQKDR--ISTISSRYLSDNQKTLGTEISLAP 589
            RQ+    +++  + +P A M   Y  I  +LW +  + + ++++ + HR+    M+++I++ F VCW P  +++++  +   + +  N  T   II +  AIGF N+   P +YA  N+ FK++   T      +PV +   R  +S   S++L     + G E  L P
Sbjct:  223 RQLYTTFIMVALFLLPLAAMLFLYSRIGVELWIRKRVGDASVLSTMNHREITVKMMITIVLLFTVCWAPFHIVHMLFEYN-DLEKKYNEVTVNMIIAVVQAIGFSNSFNNPIVYAFMNENFKKSCLSTLSSYLRRPVQQSVPRQNLSVHFSKHLKTEAFS-GAEEHLEP 389

[Close]

BLAST of SMED30006077 vs. Ensembl Xenopus
Match: taf1b (TATA-box binding protein associated factor, RNA polymerase I, B [Source:Xenbase;Acc:XB-GENE-992275])

HSP 1 Score: 67.781 bits (164), Expect = 7.658e-13
Identity = 43/143 (30.07%), Postives = 66/143 (46.15%), Query Frame = -2

Query:  188 KGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHC-------QPVGEQK 595
            +   I  + M+I+ Y +P A++  AY+ I  KL KNH+         Q RK  T MLV +++ F VCW P  +  L     W +   +N + +  I + +  C+    PFLY   NK ++  F   F C       QP G  +
Sbjct:  200 RDSTIYSLSMLILQYALPLAVICYAYLRIWFKL-KNHISPTTRSESQQRRKNTTKMLVMMVVVFAVCWLPFHIFQLAIDLEWTVAIHEN-KLLYTIFHVVAMCSTFVNPFLYGWMNKNYRHGFLTFFGCKDTLQNSQPDGSLR 340

[Close]

BLAST of SMED30006077 vs. Ensembl Xenopus
Match: sp3 (Sp3 transcription factor [Source:Xenbase;Acc:XB-GENE-977158])

HSP 1 Score: 64.3142 bits (155), Expect = 1.230e-11
Identity = 37/159 (23.27%), Postives = 78/159 (49.06%), Query Frame = -2

Query:  119 KGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEIS 595
            + R+I+     IV Y IP  I++ +Y   I  LW    P E M    + ++KVT M++ + + F +CW P  V+ +  ++G      Q       +++ + + N+   P +YA  +K F++ F++ F C    + ++++  +++ +         +E+S
Sbjct:  184 RTRKIMDTGTFIVGYVIPVLIVSLSYTRTIKYLWTAVDPLEDMSESKKAKRKVTKMIIIVTVLFCLCWLPHHVVVMCYLYG-DFPFNQATYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFQKVFSCLLRKKGRNKVHVVNAAHAEPGFDAASSEMS 341

[Close]

BLAST of SMED30006077 vs. Ensembl Xenopus
Match: sp3 (Sp3 transcription factor [Source:Xenbase;Acc:XB-GENE-977158])

HSP 1 Score: 64.3142 bits (155), Expect = 1.399e-11
Identity = 37/159 (23.27%), Postives = 78/159 (49.06%), Query Frame = -2

Query:  119 KGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEIS 595
            + R+I+     IV Y IP  I++ +Y   I  LW    P E M    + ++KVT M++ + + F +CW P  V+ +  ++G      Q       +++ + + N+   P +YA  +K F++ F++ F C    + ++++  +++ +         +E+S
Sbjct:  207 RTRKIMDTGTFIVGYVIPVLIVSLSYTRTIKYLWTAVDPLEDMSESKKAKRKVTKMIIIVTVLFCLCWLPHHVVVMCYLYG-DFPFNQATYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFQKVFSCLLRKKGRNKVHVVNAAHAEPGFDAASSEMS 364

[Close]

BLAST of SMED30006077 vs. Ensembl Xenopus
Match: NPY2R (neuropeptide Y receptor Y2 [Source:NCBI gene;Acc:100498351])

HSP 1 Score: 63.1586 bits (152), Expect = 3.605e-11
Identity = 40/122 (32.79%), Postives = 61/122 (50.00%), Query Frame = -2

Query:  206 MIIVFYFIPAAIMTSAYICIICKLWKNHM-PNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQ 568
            M+++ Y +P AI++ AYI I  KL KNH+ P        Q R+K T MLV++++ F VCW P     L      ++     ++ I  I + I  C+    P LY   N  ++ AF   F C+
Sbjct:  245 MLLIQYIVPLAIISYAYIRIWTKL-KNHVSPGGGNDHYHQRRRKTTKMLVAVVVVFAVCWLPFHAFQLASDIDGKVLDLNEYKLIYTIFHVIAMCSTFANPLLYGWMNNNYRTAFLTAFKCE 365

[Close]

BLAST of SMED30006077 vs. Ensembl Xenopus
Match: HCRTR2 (hypocretin (orexin) receptor 2 [Source:NCBI gene;Acc:100495420])

HSP 1 Score: 60.8474 bits (146), Expect = 1.977e-10
Identity = 47/194 (24.23%), Postives = 87/194 (44.85%), Query Frame = -2

Query:  119 QILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPN-------------------------------EAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVD-VFGWRITQTQNHRTI---IFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVG---EQKDRISTISSRYLSDNQKTLGTEIS 586
            ++ ++    + Y +P  +M  AY+ I  KLW   +P                                 A I +I  R+K   ML+ +L+ F +C+ P+ ++N++  VFG   T T +  T+      ++ + + N+   P +Y   + KF++ F+  F C   G    Q DR+  I  R  ++++K+L T+IS
Sbjct:  219 KVYHICFFCITYMVPLCLMILAYLQIFRKLWCRQIPGTSSVVQKKWKPLQCSIQSKGQQSTKSRNNAVAAEIKQIHARRKTARMLMVVLLVFALCYLPISILNILKRVFG-MFTHTNDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCRGIHNNQDDRL--IRGRASTESRKSLTTQIS 409

[Close]

BLAST of SMED30006077 vs. Ensembl Mouse
Match: Tacr2 (tachykinin receptor 2 [Source:MGI Symbol;Acc:MGI:98477])

HSP 1 Score: 67.781 bits (164), Expect = 5.421e-13
Identity = 38/152 (25.00%), Postives = 76/152 (50.00%), Query Frame = -2

Query:  176 PDLIKGRQIL--YVIMIIVFYFIPAAIMTSAYICIICKLWKNHMP----NEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVG--EQKDRIS 607
            P+   G+ +L  ++++ ++ YF+P  +M +AY  I   LWK  +P    + A +  +Q +KK    +V +++TF +CW P  +  ++  F   I   +  + +      +   + ++ P +Y   N +F+  FR  F C P G   ++DR+ 
Sbjct:  186 PNDNGGKMLLLYHLVVFVLIYFLPLVVMFAAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVVTFAICWLPYHLYFILGTFQEDIYYRKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWGTPTEEDRLE 337

[Close]

BLAST of SMED30006077 vs. Ensembl Mouse
Match: Hcrtr2 (hypocretin (orexin) receptor 2 [Source:MGI Symbol;Acc:MGI:2680765])

HSP 1 Score: 58.9214 bits (141), Expect = 8.150e-10
Identity = 47/195 (24.10%), Postives = 90/195 (46.15%), Query Frame = -2

Query:  119 QILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPN--------------------------------EAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVD-VFGWRITQTQNHRTI---IFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVG---EQKDRISTISSRYLSDNQKTLGTEIS 586
            ++ ++   +V Y  P  +M  AY+ I  KLW   +P                                  A I +I+ R+K   ML+ +L+ F +C+ P+ ++N++  VFG   T T++  T+      ++ + + N+   P +Y   + KF++ F+  F C  +G    Q DR++    R  ++++K+L T+IS
Sbjct:  221 KMYHICFFLVTYMAPLCLMILAYLQIFRKLWCRQIPGTSSVVQRKWKQQQPVSQPRGSGQQSKARISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFG-MFTHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCC-LGVHHRQGDRLA--RGRTSTESRKSLTTQIS 411

[Close]

BLAST of SMED30006077 vs. Ensembl Mouse
Match: Hcrtr2 (hypocretin (orexin) receptor 2 [Source:MGI Symbol;Acc:MGI:2680765])

HSP 1 Score: 58.9214 bits (141), Expect = 8.249e-10
Identity = 47/195 (24.10%), Postives = 90/195 (46.15%), Query Frame = -2

Query:  119 QILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPN--------------------------------EAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVD-VFGWRITQTQNHRTI---IFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVG---EQKDRISTISSRYLSDNQKTLGTEIS 586
            ++ ++   +V Y  P  +M  AY+ I  KLW   +P                                  A I +I+ R+K   ML+ +L+ F +C+ P+ ++N++  VFG   T T++  T+      ++ + + N+   P +Y   + KF++ F+  F C  +G    Q DR++    R  ++++K+L T+IS
Sbjct:  221 KMYHICFFLVTYMAPLCLMILAYLQIFRKLWCRQIPGTSSVVQRKWKQQQPVSQPRGSGQQSKARISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFG-MFTHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSC-CLGVHHRQGDRLA--RGRTSTESRKSLTTQIS 411

[Close]

BLAST of SMED30006077 vs. Ensembl Mouse
Match: Oprk1 (opioid receptor, kappa 1 [Source:MGI Symbol;Acc:MGI:97439])

HSP 1 Score: 55.0694 bits (131), Expect = 1.498e-8
Identity = 37/134 (27.61%), Postives = 70/134 (52.24%), Query Frame = -2

Query:  173 IMIIVFYF-IPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRIST 571
            I + VF F IP  I+   Y  +I +L    + + +   + ++ +++T +++ ++  F +CWTP+ +  LV+  G     T    +  F   A+G+ N+   P LYA  ++ FK+ FR+   C P+  + +R ST
Sbjct:  228 ICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSR-EKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCI-ALGYTNSSLNPVLYAFLDENFKRCFRD--FCFPIKMRMERQST 357

[Close]

Query:  173 IMIIVFYF-IPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRIST 571
            I + VF F IP  I+   Y  +I +L    + + +   + ++ +++T +++ ++  F +CWTP+ +  LV+  G     T    +  F   A+G+ N+   P LYA  ++ FK+ FR+   C P+  + +R ST
Sbjct:  228 ICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSR-EKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCI-ALGYTNSSLNPVLYAFLDENFKRCFRD--FCFPIKMRMERQST 357

[Close]

BLAST of SMED30006077 vs. UniProt/SwissProt
Match: sp|Q8WPA2|AR_BOMMO (Allatostatin-A receptor OS=Bombyx mori OX=7091 GN=AR PE=2 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 2.472e-12
Identity = 38/117 (32.48%), Postives = 65/117 (55.56%), Query Frame = -2

Query:  203 YFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQP 553
            Y IP A+++  Y+C++ +LWK+           + RKKVT M+V +++ F VCW P+Q+I LV     +   T    T   +++ + + N+   P LYA  ++ F+ AFR+  +C P
Sbjct:  218 YVIPLALISVLYMCMLTRLWKSAPGGRVSAESRRGRKKVTRMVVVVVVVFAVCWCPIQIILLVKALN-KYHITYFTVTAQIVSHVLAYMNSCVNPVLYAFLSENFRVAFRKVMYCPP 333

[Close]

BLAST of SMED30006077 vs. UniProt/SwissProt
Match: sp|P30549|NK2R_MOUSE (Substance-K receptor OS=Mus musculus OX=10090 GN=Tacr2 PE=2 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 3.792e-12
Identity = 38/152 (25.00%), Postives = 76/152 (50.00%), Query Frame = -2

Query:  176 PDLIKGRQIL--YVIMIIVFYFIPAAIMTSAYICIICKLWKNHMP----NEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVG--EQKDRIS 607
            P+   G+ +L  ++++ ++ YF+P  +M +AY  I   LWK  +P    + A +  +Q +KK    +V +++TF +CW P  +  ++  F   I   +  + +      +   + ++ P +Y   N +F+  FR  F C P G   ++DR+ 
Sbjct:  186 PNDNGGKMLLLYHLVVFVLIYFLPLVVMFAAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVVTFAICWLPYHLYFILGTFQEDIYYRKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWGTPTEEDRLE 337

[Close]

BLAST of SMED30006077 vs. UniProt/SwissProt
Match: sp|P16610|NK2R_RAT (Substance-K receptor OS=Rattus norvegicus OX=10116 GN=Tacr2 PE=2 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 3.353e-11
Identity = 39/160 (24.38%), Postives = 77/160 (48.12%), Query Frame = -2

Query:  152 PDLIKGRQIL--YVIMIIVFYFIPAAIMTSAYICIICKLWKNHMP----NEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQP--VGEQKDRISTISSRYLS 607
            P+   G+ +L  ++++ ++ YF+P  +M  AY  I   LWK  +P    + A +  +Q +KK    +V +++TF +CW P  +  ++  F   I   +  + +      +   + ++ P +Y   N +F+  FR  F C P     ++DR+    +  LS
Sbjct:  186 PNDNGGKMLLLYHLVVFVLIYFLPLLVMFGAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVLTFAICWLPYHLYFILGTFQEDIYYHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTHTPSLS 345

[Close]

BLAST of SMED30006077 vs. UniProt/SwissProt
Match: sp|P51144|NK2R_MESAU (Substance-K receptor OS=Mesocricetus auratus OX=10036 GN=TACR2 PE=2 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 1.097e-10
Identity = 44/179 (24.58%), Postives = 85/179 (47.49%), Query Frame = -2

Query:   95 PDLIKGRQIL--YVIMIIVFYFIPAAIMTSAYICIICKLWKNHMP-NEAMIARIQH---RKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQP--VGEQKDRISTISSRYLSDNQKTLGTEISLAPLTRMT 607
            P+   G+ +L  ++++ ++ YF+P  +M  AY  I   LWK  +P ++A  A ++H   +KK    +V +++TF +CW P  +  ++  F   I   +  + +      +   + ++ P +Y   N +F+  FR  F C P     ++DR+    +  LS       T+ +L     MT
Sbjct:  186 PNDNGGKMLLLYHLVVFVLVYFLPLVVMFVAYSVIGLTLWKRAVPRHQAHGANLRHLHAKKKFVKAMVLVVLTFAICWLPYHLYFILGSFQKDIYYRKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTRTPSLSRRVNRCHTKETLFMTADMT 364

[Close]

BLAST of SMED30006077 vs. UniProt/SwissProt
Match: sp|O62809|OX2R_PIG (Orexin receptor type 2 OS=Sus scrofa OX=9823 GN=HCRTR2 PE=2 SV=2)

HSP 1 Score: 63.1586 bits (152), Expect = 1.672e-10
Identity = 47/195 (24.10%), Postives = 91/195 (46.67%), Query Frame = -2

Query:  119 QILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPN--------------------------------EAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVD-VFGWRITQTQNHRTI---IFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVG---EQKDRISTISSRYLSDNQKTLGTEIS 586
            ++ ++   +V Y  P  +M  AY+ I  KLW   +P                                  A I +I+ R+K   ML+ +L+ F +C+ P+ ++N++  VFG   T T++  T+      ++ + + N+   P +Y   + KF++ F+  F C  +G    Q+DR++    R  ++++K+L T+IS
Sbjct:  221 KMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQQTKSRISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFG-MFTHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLA--RGRTSTESRKSLTTQIS 412

[Close]

BLAST of SMED30006077 vs. TrEMBL
Match: K1PQQ9 (Pyroglutamylated RFamide peptide receptor OS=Crassostrea gigas OX=29159 GN=CGI_10004377 PE=3 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 9.842e-21
Identity = 56/171 (32.75%), Postives = 87/171 (50.88%), Query Frame = -2

Query:   98 GRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARI----QHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQT--QNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEISLAPLTRM 592
            GR   Y I+  + YFIP  +M  AYIC+I  LW +  P E     +    + ++KV  MLV IL  F +CW P+QV  L   +   +T T  + +    +I   + F N+   P LYAG N  F++ F++ F C     +K R +T+S     D + T  +  ++ P+T+M
Sbjct:  244 GRMAYYTIISFILYFIPLVVMAVAYICVIRTLWTSKAPGERTTKDVNIQTKVKRKVVIMLVFILAVFGLCWMPLQVAVLYSEYK-PLTDTLWEGYEDFYYIAQVLAFSNSAINPLLYAGFNDNFRKGFKQMFGCY----KKKRYTTLSK---VDGEDTYHSSTTMTPVTKM 406

[Close]

BLAST of SMED30006077 vs. TrEMBL
Match: A0A1S3J712 (QRFP-like peptide receptor OS=Lingula unguis OX=7574 GN=LOC106170746 PE=3 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 7.312e-17
Identity = 52/145 (35.86%), Postives = 73/145 (50.34%), Query Frame = -2

Query:  179 GRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQH----RKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQN---HRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRI 592
             R   Y  + +V YFIP  IM  AY  II KLW + +P E +   I      +KKV  ML  IL+ + +CWTP Q++ L   +G +    QN   +    F    I + N+ F PF+YAG N+ F++ F+E   C   G    RI
Sbjct:  246 SRTFYYTFVSVVLYFIPIGIMIVAYAMIIWKLWSSELPGEQIEYEIDAQNKIKKKVVIMLCVILLVYVICWTPFQILVLWYEYG-KHKHLQNPPWYPKFEFFAQFISYSNSAFNPFIYAGFNENFRKGFKELLSC---GTDATRI 386

[Close]

BLAST of SMED30006077 vs. TrEMBL
Match: A0A2C9K062 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106074829 PE=3 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 9.934e-16
Identity = 48/144 (33.33%), Postives = 76/144 (52.78%), Query Frame = -2

Query:  176 KGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMP----NEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRIS 595
            +G+ + Y +  IV YF+P  IM   Y  I  KL     P    N    A+ + +KKV  MLV++L+ F +CWTP Q + L+ V G   T++    T +F    + + N+   P LY G N+ F++ F E F C  V +++++I 
Sbjct:  209 RGKVVYYCVEGIVMYFLPIVIMIVTYSIISVKLLHRRAPGSLINSTSSAQDKSKKKVIKMLVAVLVVFTLCWTPQQTLLLMSVLGKPTTRSDIKYTAVF----VAYFNSALNPILYGGFNENFRKGFSEAFKCVLV-QKRNKIG 347

[Close]

BLAST of SMED30006077 vs. TrEMBL
Match: A0A0K0PUK6 (Orphan G-protein coupled receptor 59 OS=Platynereis dumerilii OX=6359 PE=2 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.513e-15
Identity = 48/154 (31.17%), Postives = 80/154 (51.95%), Query Frame = -2

Query:  167 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQH----RKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTII---------FITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTIS 589
            R   Y  + +V YF P  +M+ AY  II KLW +HMP E + + ++     +K+V  MLV IL  F +CW P Q+  L +       + ++++TI          +  N I + N+ F P +Y G N+ FK+ F+  F C+   ++ + IS ++
Sbjct:  227 RTAYYTFISLVLYFFPILVMSIAYSFIIWKLWSSHMPGERIESEVRSQDRIKKRVIIMLVIILSVFALCWLPFQIAILYN-------EHRSNKTISLPLWYGNFNYFANYIAYANSAFNPVIYTGFNENFKRGFKSLFGCKKPAKKYNAISGMT 373

[Close]

BLAST of SMED30006077 vs. TrEMBL
Match: A0A4Y2QXH5 (Substance-K receptor OS=Araneus ventricosus OX=182803 GN=TACR2 PE=4 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 2.146e-15
Identity = 57/181 (31.49%), Postives = 86/181 (47.51%), Query Frame = -2

Query:   92 DLIKGRQI------LYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARI----QHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEISLAPLTRMTS 604
            DL + RQI       YV   I  YFIP  +M +AY  I+ KLW + +P E   A I    + RKKV  M++ +LI F +CWTP+Q+   +          +      +++N + F N+   P +Y G NK F+  F     C   G ++DR +      L     T  T ++ +P +R TS
Sbjct:   38 DLHECRQIEQYRFTYYVTCSIALYFIPVIVMMTAYSLILWKLWISEVPGERHAANINVQYRARKKVIKMVLVVLIAFIICWTPMQIQIYISALQSEAQSDKWIEQYQWVSNYLAFANSFINPIIYGGFNKTFRDGFCIMLRC---GYRRDRFARNPRSRL-----TFTTGVTSSP-SRFTS 209

[Close]

BLAST of SMED30006077 vs. Ensembl Cavefish
Match: tacr1b (substance-P receptor-like [Source:NCBI gene;Acc:103042892])

HSP 1 Score: 63.1586 bits (152), Expect = 2.219e-11
Identity = 44/172 (25.58%), Postives = 85/172 (49.42%), Query Frame = -2

Query:   92 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMI---ARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFH---CQPVGEQKDRISTISSRYLSDNQKTLGTEISLAPLTRMTS 589
            +Q+ YV + ++ YF+P  +M  AY+ + C LW + +P ++      ++  ++KV  M++ ++ TF VCW P  V  L+  F   + + +  + +      +   + ++ P +Y   N +F+  F+  F    C P G  +  +   S+RYL        T+ISL   +RM +
Sbjct:  199 KQMYYVCVAVLIYFLPLLVMGCAYLVVGCTLWASEIPGDSSDRYREQLNAKRKVVKMMIVVVCTFAVCWLPYHVYFLLHQFFPHLFEERFIQQVYLGIMWLAMSSTMYNPIIYCFLNDRFRAGFQRAFSWCPCAPRGSYEG-LELKSTRYLQ-------TQISLYRASRMET 362

[Close]

Query:   92 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMI---ARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFH---CQPVGEQKDRISTISSRYLSDNQKTLGTEISLAPLTRMTS 589
            +Q+ YV + ++ YF+P  +M  AY+ + C LW + +P ++      ++  ++KV  M++ ++ TF VCW P  V  L+  F   + + +  + +      +   + ++ P +Y   N +F+  F+  F    C P G  +  +   S+RYL        T+ISL   +RM +
Sbjct:  199 KQMYYVCVAVLIYFLPLLVMGCAYLVVGCTLWASEIPGDSSDRYREQLNAKRKVVKMMIVVVCTFAVCWLPYHVYFLLHQFFPHLFEERFIQQVYLGIMWLAMSSTMYNPIIYCFLNDRFRAGFQRAFSWCPCAPRGSYEG-LELKSTRYLQ-------TQISLYRASRMET 362

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BLAST of SMED30006077 vs. Ensembl Cavefish
Match: hcrtr2 (hypocretin receptor 2 [Source:NCBI gene;Acc:103037678])

HSP 1 Score: 62.7734 bits (151), Expect = 2.732e-11
Identity = 51/194 (26.29%), Postives = 85/194 (43.81%), Query Frame = -2

Query:  119 QILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPN--------------------------------EAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVD-VFGWRITQTQNHRTI---IFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQ--PVGEQKDRISTISSRYLSDNQKTLGTEIS 586
            +I +    IV YF P  +M  AYI I  KLW   +P                                  A I +++ R+K   ML+ +L  F +C+ P+ V+N++  VFG     T N  T+      ++ + + N+   P +Y   + KF++ F+  F C+    G  K+R  T  S   +D+ K+L T++S
Sbjct:  224 KIYHTCFFIVTYFAPLCLMVLAYIQICHKLWCQQIPGTSSALQRKWKSLQCSAHSAGPGESVKVRTSAVSAEIKQVKARRKTARMLMVVLFVFALCYLPISVLNIMKRVFG-AFKNTNNRETVYAWFTFSHWLIYANSAANPIIYNFLSGKFREEFKAAFSCRCSGGGGTKERARTKMS---TDSHKSLSTQVS 413

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BLAST of SMED30006077 vs. Ensembl Cavefish
Match: galr2b (galanin receptor type 2-like [Source:NCBI gene;Acc:103040671])

HSP 1 Score: 60.4622 bits (145), Expect = 1.471e-10
Identity = 36/157 (22.93%), Postives = 74/157 (47.13%), Query Frame = -2

Query:  119 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEIS 589
            R++L     +  Y IP  I++ +Y   I  LW    P + M    + ++KVT M++ + + F +CW P  V+ L  ++G      Q       +++ + + N+   P +YA  +K F++ F++ F C    + ++++  +         +   TE+S
Sbjct:  186 RKVLDTCTFVFGYVIPVLIVSLSYTRTIKYLWTAVDPLDVMSESKRAKRKVTKMIIIVTVLFCICWLPYHVVILCYLYG-DFPFNQTTYAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFKKVFSCILSKKGRNKVHVVHVANTVPGFEGGSTEVS 341

[Close]

BLAST of SMED30006077 vs. Ensembl Cavefish
Match: tacr1b (substance-P receptor-like [Source:NCBI gene;Acc:103042892])

HSP 1 Score: 60.077 bits (144), Expect = 2.055e-10
Identity = 43/168 (25.60%), Postives = 82/168 (48.81%), Query Frame = -2

Query:   92 YVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMI---ARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFH---CQPVGEQKDRISTISSRYLSDNQKTLGTEISLAPLTRMTS 577
            YV + ++ YF+P  +M  AY+ + C LW + +P ++      ++  ++KV  M++ ++ TF VCW P  V  L+  F   + + +  + +      +   + ++ P +Y   N +F+  F+  F    C P G  +  +   S+RYL        T+ISL   +RM +
Sbjct:  182 YVCVAVLIYFLPLLVMGCAYLVVGCTLWASEIPGDSSDRYREQLNAKRKVVKMMIVVVCTFAVCWLPYHVYFLLHQFFPHLFEERFIQQVYLGIMWLAMSSTMYNPIIYCFLNDRFRAGFQRAFSWCPCAPRGSYEG-LELKSTRYLQ-------TQISLYRASRMET 341

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BLAST of SMED30006077 vs. Ensembl Sea Lamprey
Match: galr2a (galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-130603-37])

HSP 1 Score: 58.5362 bits (140), Expect = 1.456e-10
Identity = 33/127 (25.98%), Postives = 63/127 (49.61%), Query Frame = -2

Query:  215 KGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETF 595
            + R+++ ++  +  Y +P +++  AY   +  LW    P E M    + ++KVTTM++ +   F  CW P  V+ L   FG     T        +++ + + N+   P +YA  +K F++ FR+ F
Sbjct:  185 EPRKLMDMVTFVCGYLVPVSVLGLAYAFTLKYLWTAVDPLEEMSESKRAKRKVTTMILIVAGLFCACWLPHHVLILYFWFG-HFPLTHATYAFRLLSHCMSYANSCLNPLVYALVSKHFRKGFRKAF 310

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BLAST of SMED30006077 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005221.1 (pep scaffold:Pmarinus_7.0:GL492654:932:1932:1 gene:ENSPMAG00000004747.1 transcript:ENSPMAT00000005221.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 52.7582 bits (125), Expect = 2.975e-9
Identity = 33/106 (31.13%), Postives = 53/106 (50.00%), Query Frame = -2

Query:  185 NEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFG-WRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFH-------CQPVGEQKD 478
            N ++ A +  +K+V  ML++I++ F++CWTPV   N    F   R +Q  +   I FI + + + +A   P +Y   NK+F+QA   T         C P G  K 
Sbjct:   31 NPSLEANLLAKKRVIRMLITIVVMFFICWTPVFSANAWRAFDKCRASQVLSGAPISFI-HLMSYASACLNPIIYCFMNKRFRQACTATISRCCASVCCSPKGAAKG 135

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BLAST of SMED30006077 vs. Ensembl Sea Lamprey
Match: qrfpr4 (pyroglutamylated RFamide peptide receptor 4 [Source:ZFIN;Acc:ZDB-GENE-091204-354])

HSP 1 Score: 53.5286 bits (127), Expect = 6.885e-9
Identity = 33/138 (23.91%), Postives = 61/138 (44.20%), Query Frame = -2

Query:  209 KGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQH---------RKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHC 595
            + RQ     +++V + +P   MT+ Y  +  +LW     ++A+   +Q          +K+   M+V ++I F VCW P  V+N +   G            + +    GF N+L+ P +YA  N+ +K+       C
Sbjct:  209 EHRQAYTTTLLLVTFVLPLLTMTALYTRLAHELWVKTRVHDAVFNALQRSEINKITRSKKRAVKMMVIVVILFAVCWAPFHVVNSLVPKGNLEMSFDMEAITLAMVQLFGFSNSLWNPIVYAALNQNYKKQLAIALSC 346

[Close]

BLAST of SMED30006077 vs. Ensembl Sea Lamprey
Match: sstr1a (somatostatin receptor 1a [Source:ZFIN;Acc:ZDB-GENE-090429-1])

HSP 1 Score: 51.6026 bits (122), Expect = 2.992e-8
Identity = 35/120 (29.17%), Postives = 55/120 (45.83%), Query Frame = -2

Query:  215 IVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRK----KVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETF 562
            +V+ F    ++  A IC+   L    M   A+ A  Q RK    KVT M+  ++  F  CW P  V+ LV+VF  +   T N   +I     +G+ N+   P LY   +  F+ +F+   
Sbjct:  177 VVYTFTVGFLLPVAAICLCYALIVAKMRAVALRAGWQQRKRSERKVTLMVTMVVAVFVACWMPFYVVQLVNVFEGQQGATVNQLAVI-----LGYANSCANPILYGFLSDSFRHSFQRVL 291

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BLAST of SMED30006077 vs. Ensembl Sea Lamprey
Match: cxcr4a (chemokine (C-X-C motif) receptor 4a [Source:ZFIN;Acc:ZDB-GENE-020102-1])

HSP 1 Score: 51.2174 bits (121), Expect = 4.094e-8
Identity = 37/155 (23.87%), Postives = 65/155 (41.94%), Query Frame = -2

Query:  161 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVD-------VFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQ-----PVGEQKDRISTISSR 589
            R  L  +  ++ + +P  ++   Y+ +I  L + H            ++K   ++V+I+  F+VCW P  V+ L+D       V        Q     + +T  +GF +  F P LYA   KKFK+       C+     PV   ++     S+R
Sbjct:  211 RTSLRALHHVLAFALPGIVIVFCYVMVIRTLSQLHN---------HEKRKALKVVVAIVAAFFVCWLPYNVVTLLDTLMRLDAVVNSDCEMEQRLGVAVAVTEGVGFSHCCFIPVLYAFVGKKFKENLARLRGCKACVGTPVASYREGKRQSSNR 356

[Close]

BLAST of SMED30006077 vs. Ensembl Nematostella
Match: EDO48201 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK81])

HSP 1 Score: 73.1738 bits (178), Expect = 1.525e-15
Identity = 45/140 (32.14%), Postives = 71/140 (50.71%), Query Frame = -2

Query:  212 SFLPDLIKGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNE---AMIARIQHR-KKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHR-TIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFH 616
            S L D+   +Q+ Y  ++++ Y IP  +MT+ Y  I  KLW +  P E   A+  R++ + ++V  MLV +++ F  CW P  V+++   F WR       R  I  I   IG  N+   P LY   N +F++AF   F 
Sbjct:  162 SVLGDVDLSQQVFYAFVLVMLYIIPLVVMTTIYSSICFKLWIHRTPGETIPAVTRRVERKNRRVIRMLVIVVVVFAACWLPPHVMHIYSAFYWREFSVNITRYNIDDIMFFIGQANSAINPILYIWLNSEFRKAFGRAFR 301

[Close]

BLAST of SMED30006077 vs. Ensembl Nematostella
Match: EDO34897 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN38])

HSP 1 Score: 63.929 bits (154), Expect = 3.740e-12
Identity = 49/156 (31.41%), Postives = 79/156 (50.64%), Query Frame = -2

Query:  131 QILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIA-RIQHR--KKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHC-QPVGEQKDRISTISSRYLSDNQKTLG 586
            QI  + ++++ Y +P  +M S Y CI   LW+  +P EA  A R  HR  KKVT M+V+I+  F +CWTP  V+  ++V  + +        ++ ++ +I   N      +YA  N+ F+  F++T  C + V  Q  +         S NQ TLG
Sbjct:  227 QIWALAVLVLGYGLPLVLMLSFYGCIAWILWRRKVPGEAEQAQRNAHRTAKKVTWMVVAIMSVFEICWTPFFVMCFINV-KFPVLLLATPGELMPVSYSIVQLNGPLNMAIYAFFNENFRNGFKQTLKCFRRVAVQDAK---------SVNQLTLG 372

[Close]

BLAST of SMED30006077 vs. Ensembl Nematostella
Match: EDO36628 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI47])

HSP 1 Score: 62.003 bits (149), Expect = 1.393e-11
Identity = 34/130 (26.15%), Postives = 63/130 (48.46%), Query Frame = -2

Query:  224 DLIKGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIAR---IQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFR 604
            D+++  +I  +++ +V Y +P  +M + Y  +  KLW   +P  A       ++ RKK   ML+++ + F  CW PVQV+     F W   +       +F    +   +A   P +YA  ++ F+ AF+
Sbjct:  164 DVVQTSRIYTLVLFVVGYCVPFVVMATMYSIMFTKLWVRKIPASACSRSCQIVESRKKAVIMLITVFVVFVCCWLPVQVLG----FMWNYGEYDIPAPALFACKILMRVHAATSPCIYAAFSENFRNAFK 289

[Close]

BLAST of SMED30006077 vs. Ensembl Nematostella
Match: EDO34996 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMT8])

HSP 1 Score: 60.4622 bits (145), Expect = 4.638e-11
Identity = 34/117 (29.06%), Postives = 63/117 (53.85%), Query Frame = -2

Query:  236 VIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIA--RIQH--RKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFK 574
            +++ IV Y IP   +T  Y C+I K+W   +P     A  R++   +K+V  ML+++++TF +CW P  +  L+  F + I   Q    ++F+   +G  N+   P++Y   NK ++
Sbjct:  175 LLIFIVMYAIPLTFITCLYACVIRKVWIRQVPGNVTRANQRLEGDMKKRVLKMLITVVVTFALCWLPFHIYLLLVNFYYGIYSCQISHIVLFVGLFLGHANSAINPWIYFMFNKDYR 291

[Close]

BLAST of SMED30006077 vs. Ensembl Nematostella
Match: EDO49570 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGN9])

HSP 1 Score: 58.9214 bits (141), Expect = 1.474e-10
Identity = 39/124 (31.45%), Postives = 61/124 (49.19%), Query Frame = -2

Query:  221 VIMIIVFYFIPAAIMTSAYICIICK-LWKNHMPNEAMIARIQ-----HRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRE 574
            V++ +V Y  P   M   Y C IC+ LWK   P  A I R +      RK+V  ML+++ + F VCW P+ +   +  F  + T     +   F++  +G  N+   PFLY+  N  F++ FR 
Sbjct:  163 VLLFVVMYVAPLLTMAVLY-CAICRTLWKRTSPG-ARITRTETHLQRSRKRVLKMLLAVTLLFAVCWLPLWIFQFIMFFSPQ-TFPCFSKPFYFVSLFLGHSNSAINPFLYSFFNANFREGFRR 283

[Close]

BLAST of SMED30006077 vs. Ensembl Medaka
Match: npy7r (PRELI domain-containing protein 1, mitochondrial [Source:NCBI gene;Acc:101174272])

HSP 1 Score: 72.7886 bits (177), Expect = 8.216e-15
Identity = 40/131 (30.53%), Postives = 64/131 (48.85%), Query Frame = -2

Query:  191 ILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQ 583
            I  + M+++ Y IP A+++ AYICI  KL KNH+   +    I  RKK T ML  +++ F  CW P  V  L       + + + ++ I  + + +  C+    P LY   NK ++  F   F C+   E 
Sbjct:  212 IYSLFMLLLQYIIPLAVISYAYICIWVKL-KNHISPSSRNDNINRRKKTTKMLALVVVVFATCWLPFHVFQLASDLDL-VLRFEEYKFIYTVFHVVAMCSTFANPLLYGWMNKNYRNGFLMVFRCEDKPES 340

[Close]

BLAST of SMED30006077 vs. Ensembl Medaka
Match: galr2a (galanin receptor type 2 [Source:NCBI gene;Acc:101155603])

HSP 1 Score: 64.6994 bits (156), Expect = 5.444e-12
Identity = 36/159 (22.64%), Postives = 75/159 (47.17%), Query Frame = -2

Query:  119 KGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEIS 595
            + R++L     +  Y IP  I++ +Y   I  LW    P + M    + ++KVT M++ + + F +CW P  V+ L  ++G      Q       +++ + + N+   P +YA  +K F++ F++ F C  +   ++++  +         +   TE+S
Sbjct:  184 QDRKVLDTCTFLFGYVIPVLIVSLSYTRTIKYLWTAVDPLDGMSESKRAKRKVTKMIIIVTVLFCICWLPYHVVILCYLYG-DFPFNQTTYAFRLLSHCMAYANSCVNPIVYALVSKHFRKGFKKVFSCILIANGRNKVHVVHVANTGPGFEAASTEVS 341

[Close]

BLAST of SMED30006077 vs. Ensembl Medaka
Match: hcrtr2 (hypocretin receptor 2 [Source:NCBI gene;Acc:101170456])

HSP 1 Score: 63.929 bits (154), Expect = 1.118e-11
Identity = 43/201 (21.39%), Postives = 90/201 (44.78%), Query Frame = -2

Query:   92 QILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNE--------------------------------AMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTI---IFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEI-SLAPLTRMTS 586
            +I +    IV YF P  +M  AYI I  KLW   +P                                  A I +++ R+K   ML+ +L  F +C+ P+ ++N++         T +  T+      ++ + + N+   P +Y   + KF++ F+  F C+  G+++ +    ++R   D++K++ T++ ++  L+R++ 
Sbjct:  215 KIYHTCFFIVTYFAPLCLMVLAYIQICHKLWCQQIPGNTSVIQRKWKSIQCSAPSAALGEAARVRTSTVCAEIKQVRARRKTARMLIVVLFVFALCYLPISILNIMKRVLGSFKNTNDRETVYAWFTFSHWLIYANSAANPIIYNFLSGKFREEFKSAFSCRCCGQRQIQTKRTTTRASVDSKKSMSTQLNNMDNLSRVSE 415

[Close]

BLAST of SMED30006077 vs. Ensembl Medaka
Match: npy2rl (neuropeptide Y receptor type 2 [Source:NCBI gene;Acc:101162714])

HSP 1 Score: 61.6178 bits (148), Expect = 6.462e-11
Identity = 42/149 (28.19%), Postives = 71/149 (47.65%), Query Frame = -2

Query:  140 MIIVFYFIPAAIMTSAYICIICKLWKNHMPNE------AMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQK 568
            M+I+ YF+P +I++ AY  I  KL  +  P E      A   R + R+K T MLV++++ F V W P     L      ++   ++ R +  I + +  C+    P LY   N+ ++ AF   F C+  G  + R    + R L+  +K
Sbjct:  221 MLILQYFLPLSIISFAYARIWSKLRGHVSPAEGGANSSAGSERHRRRRKTTKMLVTMVVVFAVSWLPFHAFQLATDIDNKVLDMRDFRLLYTIFHVVAMCSTFANPLLYGWMNRNYRAAFLAVFKCRR-GADRGRSDFRARRDLTKGKK 368

[Close]

BLAST of SMED30006077 vs. Ensembl Medaka
Match: tacr1b (substance-P receptor-like [Source:NCBI gene;Acc:101168056])

HSP 1 Score: 60.4622 bits (145), Expect = 1.622e-10
Identity = 40/159 (25.16%), Postives = 74/159 (46.54%), Query Frame = -2

Query:  122 RQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQH---RKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEI 589
            R+I YV + ++ YF+P  IM  AYI +   LW + +P ++     Q    ++KV  M++ ++ TF VCW P  V  L+  F   + +    + +      +   + ++ P +Y   N +F+  F++ F C      K+ +   S R L       G+ +
Sbjct:  220 RKIYYVSVALLIYFLPLCIMGWAYITVAVTLWASKIPGDSSEHYRQQLVAKRKVVKMMIVVVCTFAVCWLPYHVYFLLHQFFPELFEQLYIQQVYLAVMWLAMSSTMYNPIIYYCLNSRFRAGFQQVFCCCSSSAAKEELELKSPRCLQTQGSIRGSRM 378

[Close]

BLAST of SMED30006077 vs. Planmine SMEST
Match: SMESG000081422.1 (SMESG000081422.1)

HSP 1 Score: 356.295 bits (913), Expect = 2.104e-124
Identity = 169/171 (98.83%), Postives = 171/171 (100.00%), Query Frame = -2

Query:   92 DLIKGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEISLAPLTRMTS 604
            +LIKGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHC+PVGEQKDRISTISSRYLSDNQKTLGTEISLAPLTRMTS
Sbjct:  184 NLIKGRQILYVIMIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCEPVGEQKDRISTISSRYLSDNQKTLGTEISLAPLTRMTS 354

[Close]

BLAST of SMED30006077 vs. Planmine SMEST
Match: SMESG000016325.1 (SMESG000016325.1)

HSP 1 Score: 69.3218 bits (168), Expect = 1.146e-13
Identity = 45/156 (28.85%), Postives = 82/156 (52.56%), Query Frame = -2

Query:  182 KSFLPDLIKGRQILYVIMIIVFYFIPAAIMTSAYICIICKLW-----KNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHCQ-----PVGEQKDR 619
            K +  D + G+ I Y +  ++FY  P  I++  Y  +I +L      K    N+AM+ +    K+VT M++ +++ F +CW P+Q I ++ ++G +       RTI  I+N + + N++  PFLYA  ++ F++AF     C+       G  +DR
Sbjct:  206 KRYEDDKVFGK-IYYTLFFVMFYLWPVIIISVLYGFLIYRLLCGRSSKISHSNDAMVTK----KRVTKMVIVVIVIFTLCWAPIQTIFIIQLYG-KDPGGNLFRTIHVISNCLAYSNSMVNPFLYAFLSENFRRAFANLLCCRRLKSFATGTIRDR 355

[Close]

BLAST of SMED30006077 vs. Planmine SMEST
Match: SMESG000023192.1 (SMESG000023192.1)

HSP 1 Score: 60.8474 bits (146), Expect = 9.405e-11
Identity = 41/172 (23.84%), Postives = 74/172 (43.02%), Query Frame = -2

Query:  125 MIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIAR---IQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFH---------------------CQPVGEQKDRISTISSRYLSDNQKTLGTE 568
            ++I+ Y +P  ++T  YI I  +LWK+    E   ++   ++ ++K+  ML++I+I F VCW P Q   ++      +  + N   + FI  A+    +   P +Y   +KKF+  F+  F                      C       D  S  + R L +N+K + T 
Sbjct:  190 LLILQYILPLVVLTITYIPISIRLWKSTTVGELNRSQRECMKTKRKIVKMLIAIIIIFAVCWLPYQCFFIIIDLNKHLNASPNVLIVFFIIYALAMSYSFTNPLIYCIMSKKFRMGFKSFFRWCPFVTWPLAQTDLKTQTNRSCDYFKGNNDLTSNGTERLLVENEKNIVTS 361

[Close]

BLAST of SMED30006077 vs. Planmine SMEST
Match: SMESG000035936.1 (SMESG000035936.1)

HSP 1 Score: 60.4622 bits (145), Expect = 1.137e-10
Identity = 40/126 (31.75%), Postives = 61/126 (48.41%), Query Frame = -2

Query:  224 QILYVIMIIVF-YFIPAAIMTSAYICIICKLWKNHMPNEAMIAR----IQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYPFLYAGHNKKFKQAFR 586
            QI Y I I++  YF+P  ++T  Y  +  KLWK  +P EA   R    ++ + KV  ML  I+I F +CW P+ +  +V         T+N      + + I   N+   P +Y+  N  FK  FR
Sbjct:  190 QISYTISILLITYFLPLIVLTVTYTIVGIKLWKRSLPGEADEIRDAKHMKSKVKVIKMLSIIVICFGLCWLPLHLFFVVTHVNQSQGYTKNLNIAYVVCHWIAMSNSFVNPVVYSFMNDSFKSDFR 315

[Close]

BLAST of SMED30006077 vs. Planmine SMEST
Match: SMESG000066072.1 (SMESG000066072.1)

HSP 1 Score: 59.6918 bits (143), Expect = 1.925e-10
Identity = 32/103 (31.07%), Postives = 55/103 (53.40%), Query Frame = -2

Query:  209 KLWKNHMPNEAMIARIQHRKKVTTMLVSILITFYVCWTPVQVINLVDVFGWRITQTQNHR-----TIIFITNAIGFCNALFYPFLYAGHNKKFKQAFRETFHC 502
            KL K       ++  I+ ++K   ML+++++ F VCW P+ V+ ++    +   Q++ +      TI FI + I  C+AL+ PFLY   N+ F+Q F   F C
Sbjct:  224 KLSKKIKSLSRVLNDIKRKRKTNKMLIAMVVIFIVCWIPLNVLWIITDLIYSDEQSKLNTNLYFTTIFFICHLIAMCSALYNPFLYGWMNENFRQEFCSVFSC 326

The following BLAST results are available for this feature:

BLAST of SMED30006077 vs. Ensembl Human
BLAST of SMED30006077 vs. Ensembl Celegans
BLAST of SMED30006077 vs. Ensembl Fly
BLAST of SMED30006077 vs. Ensembl Zebrafish
BLAST of SMED30006077 vs. Ensembl Xenopus
BLAST of SMED30006077 vs. Ensembl Mouse
BLAST of SMED30006077 vs. UniProt/SwissProt
BLAST of SMED30006077 vs. TrEMBL
BLAST of SMED30006077 vs. Ensembl Cavefish
BLAST of SMED30006077 vs. Ensembl Sea Lamprey
BLAST of SMED30006077 vs. Ensembl Yeast
BLAST of SMED30006077 vs. Ensembl Nematostella
BLAST of SMED30006077 vs. Ensembl Medaka
BLAST of SMED30006077 vs. Planmine SMEST

BLAST of SMED30006077 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TACR2	7.903e-11	24.38	tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC...	[more]
TACR2	8.187e-11	24.38	tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC...	[more]
HCRTR2	1.994e-10	23.59	hypocretin receptor 2 [Source:HGNC Symbol;Acc:HGNC...	[more]
HCRTR2	1.994e-10	23.59	hypocretin receptor 2 [Source:HGNC Symbol;Acc:HGNC...	[more]
TACR3	2.196e-9	20.90	tachykinin receptor 3 [Source:HGNC Symbol;Acc:HGNC...	[more]

BLAST of SMED30006077 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
npr-34	3.981e-10	30.00	NeuroPeptide Receptor family [Source:UniProtKB/Tr...	[more]
tkr-3	3.851e-8	22.31	TachyKinin Receptor family [Source:UniProtKB/TrEM...	[more]
nmur-2	3.524e-7	26.55	NMUR (NeuroMedin U Receptor) homolog [Source:UniP...	[more]
ser-1	1.556e-6	30.95	SERotonin/octopamine receptor family; Serotonin re...	[more]
ser-1	1.588e-6	30.95	SERotonin/octopamine receptor family; Serotonin re...	[more]

BLAST of SMED30006077 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Lkr	1.225e-12	28.69	gene:FBgn0035610 transcript:FBtr0077149	[more]
SIFaR	4.677e-9	29.13	gene:FBgn0038880 transcript:FBtr0084098	[more]
SIFaR	4.677e-9	29.13	gene:FBgn0038880 transcript:FBtr0301815	[more]
sNPF-R	3.175e-8	23.31	gene:FBgn0036934 transcript:FBtr0332667	[more]
sNPF-R	3.175e-8	23.31	gene:FBgn0036934 transcript:FBtr0074871	[more]

BLAST of SMED30006077 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
npy2rl	2.500e-12	26.90	neuropeptide Y receptor Y2, like [Source:ZFIN;Acc:...	[more]
hcrtr2	2.399e-11	23.44	hypocretin (orexin) receptor 2 [Source:ZFIN;Acc:ZD...	[more]
galr2b	3.602e-11	22.93	galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-1311...	[more]
galr2b	3.602e-11	22.93	galanin receptor 2b [Source:ZFIN;Acc:ZDB-GENE-1311...	[more]
CABZ01084347.1	3.620e-11	26.04	pyroglutamylated RFamide peptide receptor b [Sourc...	[more]

BLAST of SMED30006077 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
taf1b	7.658e-13	30.07	TATA-box binding protein associated factor, RNA po...	[more]
sp3	1.230e-11	23.27	Sp3 transcription factor [Source:Xenbase;Acc:XB-GE...	[more]
sp3	1.399e-11	23.27	Sp3 transcription factor [Source:Xenbase;Acc:XB-GE...	[more]
NPY2R	3.605e-11	32.79	neuropeptide Y receptor Y2 [Source:NCBI gene;Acc:1...	[more]
HCRTR2	1.977e-10	24.23	hypocretin (orexin) receptor 2 [Source:NCBI gene;A...	[more]

BLAST of SMED30006077 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tacr2	5.421e-13	25.00	tachykinin receptor 2 [Source:MGI Symbol;Acc:MGI:9...	[more]
Hcrtr2	8.150e-10	24.10	hypocretin (orexin) receptor 2 [Source:MGI Symbol;...	[more]
Hcrtr2	8.249e-10	24.10	hypocretin (orexin) receptor 2 [Source:MGI Symbol;...	[more]
Oprk1	1.498e-8	27.61	opioid receptor, kappa 1 [Source:MGI Symbol;Acc:MG...	[more]
Oprk1	1.498e-8	27.61	opioid receptor, kappa 1 [Source:MGI Symbol;Acc:MG...	[more]

BLAST of SMED30006077 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8WPA2\|AR_BOMMO	2.472e-12	32.48	Allatostatin-A receptor OS=Bombyx mori OX=7091 GN=...	[more]
sp\|P30549\|NK2R_MOUSE	3.792e-12	25.00	Substance-K receptor OS=Mus musculus OX=10090 GN=T...	[more]
sp\|P16610\|NK2R_RAT	3.353e-11	24.38	Substance-K receptor OS=Rattus norvegicus OX=10116...	[more]
sp\|P51144\|NK2R_MESAU	1.097e-10	24.58	Substance-K receptor OS=Mesocricetus auratus OX=10...	[more]
sp\|O62809\|OX2R_PIG	1.672e-10	24.10	Orexin receptor type 2 OS=Sus scrofa OX=9823 GN=HC...	[more]

BLAST of SMED30006077 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
K1PQQ9	9.842e-21	32.75	Pyroglutamylated RFamide peptide receptor OS=Crass...	[more]
A0A1S3J712	7.312e-17	35.86	QRFP-like peptide receptor OS=Lingula unguis OX=75...	[more]
A0A2C9K062	9.934e-16	33.33	G_PROTEIN_RECEP_F1_2 domain-containing protein OS=...	[more]
A0A0K0PUK6	1.513e-15	31.17	Orphan G-protein coupled receptor 59 OS=Platynerei...	[more]
A0A4Y2QXH5	2.146e-15	31.49	Substance-K receptor OS=Araneus ventricosus OX=182...	[more]

BLAST of SMED30006077 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tacr1b	2.219e-11	25.58	substance-P receptor-like [Source:NCBI gene;Acc:10...	[more]
tacr1b	2.219e-11	25.58	substance-P receptor-like [Source:NCBI gene;Acc:10...	[more]
hcrtr2	2.732e-11	26.29	hypocretin receptor 2 [Source:NCBI gene;Acc:103037...	[more]
galr2b	1.471e-10	22.93	galanin receptor type 2-like [Source:NCBI gene;Acc...	[more]
tacr1b	2.055e-10	25.60	substance-P receptor-like [Source:NCBI gene;Acc:10...	[more]

BLAST of SMED30006077 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
galr2a	1.456e-10	25.98	galanin receptor 2a [Source:ZFIN;Acc:ZDB-GENE-1306...	[more]
ENSPMAT00000005221.1	2.975e-9	31.13	pep scaffold:Pmarinus_7.0:GL492654:932:1932:1 gene...	[more]
qrfpr4	6.885e-9	23.91	pyroglutamylated RFamide peptide receptor 4 [Sourc...	[more]
sstr1a	2.992e-8	29.17	somatostatin receptor 1a [Source:ZFIN;Acc:ZDB-GENE...	[more]
cxcr4a	4.094e-8	23.87	chemokine (C-X-C motif) receptor 4a [Source:ZFIN;A...	[more]

BLAST of SMED30006077 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SMED30006077 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO48201	1.525e-15	32.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34897	3.740e-12	31.41	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36628	1.393e-11	26.15	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34996	4.638e-11	29.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49570	1.474e-10	31.45	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SMED30006077 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
npy7r	8.216e-15	30.53	PRELI domain-containing protein 1, mitochondrial [...	[more]
galr2a	5.444e-12	22.64	galanin receptor type 2 [Source:NCBI gene;Acc:1011...	[more]
hcrtr2	1.118e-11	21.39	hypocretin receptor 2 [Source:NCBI gene;Acc:101170...	[more]
npy2rl	6.462e-11	28.19	neuropeptide Y receptor type 2 [Source:NCBI gene;A...	[more]
tacr1b	1.622e-10	25.16	substance-P receptor-like [Source:NCBI gene;Acc:10...	[more]

BLAST of SMED30006077 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000081422.1	2.104e-124	98.83	SMESG000081422.1	[more]
SMESG000016325.1	1.146e-13	28.85	SMESG000016325.1	[more]
SMESG000023192.1	9.405e-11	23.84	SMESG000023192.1	[more]
SMESG000035936.1	1.137e-10	31.75	SMESG000035936.1	[more]
SMESG000066072.1	1.925e-10	31.07	SMESG000066072.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30006077 ID=SMED30006077|Name=SMED30006077|organism=Schmidtea mediterranea sexual|type=transcript|length=647bp
CTACGGATGAATTTTTTGACAAAAGATTCTAAAAACATGTTACTATTCAG
TACATTTTCTGTACAATCGCTGAGAAAGCTGGGTACATTTATGAAGTCAT
TCTTGTTAGAGGAGCCAAGGATATTTCTGTTCCCAAAGTTTTTTGATTGT
CACTCAAGTAGCGACTAGAAATTGTACTTATTCGATCTTTCTGTTCACCG
ACTGGCTGGCAATGAAATGTCTCCCGGAACGCTTGTTTAAATTTTTTATT
ATGTCCAGCATATAAAAATGGATAGAAAAGAGCATTGCAAAATCCAATAG
CATTCGTGATAAATATTATGGTTCGATGGTTTTGAGTTTGCGTAATTCTC
CATCCAAAAACATCCACTAGATTAATAACCTGGACAGGAGTCCAGCACAC
ATAAAATGTAATTAAAATTGAAACAAGCATTGTTGTAACTTTTTTCCTAT
GTTGTATCCGAGCTATCATTGCTTCATTAGGCATGTGATTCTTCCATAAT
TTACATATAATGCATATGTACGCACTCGTCATAATTGCAGCAGGAATAAA
GTAAAACACAATAATCATAATCACGTATAAAATTTGTCTGCCCTTGATTA
GATCTGGAAGAAAAGATTTAAAAACTAACGAAGAATGTTAAATAGAA

protein sequence of SMED30006077-orf-1

>SMED30006077-orf-1 ID=SMED30006077-orf-1|Name=SMED30006077-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=160bp
MIIVFYFIPAAIMTSAYICIICKLWKNHMPNEAMIARIQHRKKVTTMLVS
ILITFYVCWTPVQVINLVDVFGWRITQTQNHRTIIFITNAIGFCNALFYP
FLYAGHNKKFKQAFRETFHCQPVGEQKDRISTISSRYLSDNQKTLGTEIS
LAPLTRMTS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR000276	GPCR_Rhodpsn
IPR017452	GPCR_Rhodpsn_7TM

Vocabulary: **biological process**
Term	Definition
GO:0007186	G-protein coupled receptor signaling pathway

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **molecular function**
Term	Definition
GO:0004930	G-protein coupled receptor activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000276	G protein-coupled receptor, rhodopsin-like	PRINTS	PR00237	GPCRRHODOPSN	coord: 44..68 score: 28.44 coord: 85..111 score: 24.38
IPR000276	G protein-coupled receptor, rhodopsin-like	PFAM	PF00001	7tm_1	coord: 2..103 e-value: 4.1E-13 score: 49.2
None	No IPR available	GENE3D	G3DSA:1.20.1070.10		coord: 1..153 e-value: 7.7E-32 score: 112.1
None	No IPR available	PANTHER	PTHR45695	FAMILY NOT NAMED	coord: 2..119
None	No IPR available	PANTHER	PTHR45695:SF5	SI:DKEY-1H24.2	coord: 2..119
None	No IPR available	CDD	cd00637	7tm_classA_rhodopsin-like	coord: 1..104 e-value: 4.76158E-19 score: 79.2438
None	No IPR available	SUPERFAMILY	SSF81321	Family A G protein-coupled receptor-like	coord: 2..133
None	No IPR available	TMHMM	TMhelix		coord: 83..105
None	No IPR available	TMHMM	TMhelix		coord: 4..25
None	No IPR available	TMHMM	TMhelix		coord: 46..68
IPR017452	GPCR, rhodopsin-like, 7TM	PROSITE	PS50262	G_PROTEIN_RECEP_F1_2	coord: 1..103 score: 17.603

Main menu

SMED30006077

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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