Abnormal spindle-like microcephaly-associated protein homolog
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30006065 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 16
Homology
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Human
Match: ASPM (abnormal spindle microtubule assembly [Source:HGNC Symbol;Acc:HGNC:19048]) HSP 1 Score: 568.54 bits (1464), Expect = 1.864e-163 Identity = 594/2185 (27.19%), Postives = 1011/2185 (46.27%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTH--LSKTKVEDIN----------------KNMPIYIE------------------ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLF----------------------------ENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT------------------------SANLFDKE-------ILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISK---------MKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSN----YKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQK----YIRGFINRRNFLKFKSAVNILEHYF------------------MGYLRRKQ----FLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRY-FAKKEFVA---KKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQK-HTKGFLVXXXXXXXXXXXXXC---QSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQC----RQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKE--KKQIILNNQAATVVQKYFKSY----ICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKK----YLSYRHSV-----------------------IVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGF-IKRK---IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFR----KHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHF---------ICQKNAAIK------------------LQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF---NAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHF---RKYLIIRRIDLEQK-AARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRN----RFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRY----ICISKFKMIKSATLIIQKHIRGIFVRLKYK---------KIIKLVVFIQKNIRANIVRTRFL---NIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFL----IRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVL-----------KRSAVVIQR 6351
D+ W ++QE F WLN I KT + ++N P E A +L SE V AI+K+ E+ L KD +K + + +++YN WL + + +SL N++ FI ++LWN DIA ++R + + +L++ L++ L +V LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + L V+H+QT DE+DF V+NL+ D+ GVRL R ++L N D+ KLR PA+ +K N+++ ++ K G + G I I HREKTL LLW + +D ++ D+L EI ++ + +LL+ WV +VC YN V N + + DGR C LIH+Y P Y+ + I TT T S FD E LLENEK+NF + S ++ +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ K H K I+Q V FL ++ + ++ Q +R LA+ ++ K+A LIQ +RRY R R+ K+K +++LQS R + +Y + + + IQ + R YL R Y+ ++ ST IIQ + + R K KA V++Q AFR + R+ + +A+IIQS+YR R Y+ +R V+IIQK ++ ++R S + IQK Y++G I R N+L+ ++A L+ F Y R +Q FL ++ ++I Q ++R R + +K+A+IIQ F+ Y FA K + +SA I++Q+ R + R+ + ++ + I IQ +R Y +K+FL + I +Q V+ +K YL ++ + L IQ+ + + + ++ + C Q+ VR YL++KQ RK+ I +Q +FR AR+ +L K IV+Q Y ++ R+ FL++K +Q R R+ + A + IQ FR + K Q +L Q+ +Q+++++Y + F K K +V +Q R RKQ ++E + + +QS RM +K+++ A L I + + + A +K Y+ RH+V I+IQ+ +R + +K + +K +A++IQKY R + I R+ +Y A+ +Q RG VRK + +++A IQ YR+YK +K + R +AI+IQ+ +R ++ ++Y +K I IQS+ R + + M +AAT+I+ + K + R Y T R++A++IQ R Y K + R Y L A ++Q RG VR+ + Q A +IQ+ YR + +++F + Q+ A+K +Q RG R++ L+Q + + R+ + L+ ++I++Q+ +R H +FL+++NA I IQ + RR+ K R+ A+ IQ R ++YQ A++++Q+ + R + R+ L Q+ +A I+Q +RG R H +S IQ+ F++ L+R++++ +++ TIF+Q R I +FL L+ + I IQ R +K + ++A + IQ FR + TFQ K+ASI+IQ+++R Y + K +R+N YIR++ + + +K +K+ L+ +KH I ++ Y+ K+ IQ+ RAN + + +KK F M+ + K Q Q+ +IQK+C+ F RK +L +++ ++ IQ+ +R+ A R+ +I +QS RG + Q M A LIQ + + + Y+ + +++ +Q + R ++ RK FL ++ + I RG+ VR Q +K ++E + A+I Q+ CY K +Y ++S ++IQ+ ++ L R+AV IQ+
Sbjct: 692 DERWKEKQEQGFTWWLNFILTPDDFTVKTNISEVNAATLLLGIENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVKAIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGEL--ISLEDNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYAKISRLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRH-QEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQR-KMQSQVKATVILQRAFREWHLRKQ-AKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVL--QSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGK-------------------MQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTY---RAAKLQREN------YIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIK-KQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRT-----QAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVR-------QKLKNVSEEKM-----AAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQK 2823 HSP 2 Score: 380.563 bits (976), Expect = 4.010e-105 Identity = 501/1967 (25.47%), Postives = 886/1967 (45.04%), Query Frame = 1
Query: 2014 RAASCIQRVWR----KYRTFYLYKT--HFIAHY-------------KEVIIVQSIVRRFL----CLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIR----GYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVV--HKV--LFKR-------------------KLEKRLRSCIIIQKYIRGF----INRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKK----EFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVR--SIICQKN--YLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQK-----------------------YIKMHQCRQKFLKLKSQVITIQKNIRAL----LQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKE-SVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRH-SVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCS----QTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQF---------RKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGY----LIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVR----------------RYCQMKLYRDT---------RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIR----------------RIDLE--QKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYL----IRKKYLEIRQKTIFIQCLVRR--------------------------YISRNRFLRLKMSVIIIQKVTRGYF----THRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL-----VVFIQKNIRANIVRTRFLNIKKSII----------------------NIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFL-AKRSYQRNLSI-----IIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY----------------CLLK--SYTLLIQQRWRFIVLKR------SAVV-IQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSE-FIKLVKNLL--YRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSISNSQYSISKDSNIKDSV-SKYRQQLSSRCENIVGSISNSDKILEQMRLNPSWDLKRRFRPNSNSKKTLSTKLGSTNSLQENNLS 7125
RAA IQ WR + R L KT F AH K +I+Q+ R ++ L ++ + +I+ QS + AR + S I IQ YR Y+ + + +K+AT+ LQS + +K YL + + L IQ R R Y ++R+S +Q +V+GYL RK+ KA++ +QS FR R+ Y KA ++IQ++Y + R+ +L ++K+ +Q +KV L K+ K + L+S I IQ++ R + R +FLK K+AV L+ + G+ RKQ + + + +Q RM + F + + +A++IQ++F+ + A + E++ + A +++Q+ + RR+ Q AIIIQ +R + +KK+ I +A++IQK R SI ++N YLK K +V+ +Q +G V+K K + QS R Y +K+Y R S IIIQ+ +R I K++LN +K I +Q KMHQ R + ++ I IQ RA +QR +Y+ KAV +Q FR + ++ + AAT++Q ++ Y + F K+K+ + TV Q+Y QFQ RY K + + I +G AR ++L H + +IQ FR M R+ FLS+K +AI+IQ+ R + K + Q IK IQ + R +++RK + H++AT IQ +R +++ + + A++VIQ+Q+ R+HY+RQ R + +Q+ R + K M +AT IQ + ++R+++++ +++ + +Q+ R + + L + ++ RK AA IQ R +V+K++ Q+A +IQ +R + F K+A+I +Q++ R Y L R+N+ + +++Q+ KG AR+ ++ +SI++Q +R + + + KL+ A+ IQ+ R C ++D A+I+IQK+ + F R Y + +QR +RK +R R D++ +AA +IQ+FYR + + + +K + V IQNY++ Y+ RK +L +++ IQ R Y S+ ++ ++ ++IQ+ + +Y Q +A + IQK F R K + K A++ IQ + + R+ F ++++ + +Q Y R + +F + + A +++Q H R F+ K+++ + L V+ IQ + I + +F IK S I IQ++YR +K Y + +++ +IQ + R RFL ++++ IIIQ+ +R L AK +++ L I +Q+ RG + + + ++A ++IQK ++ KH +I +KS + LQ +RG+L+RK FL+ + ++ N + + + A +N K++ + I IQ +FR +Q++R+ CL + +IQ+ R +L++ S ++ IQ +WRG R + K I IR NR + N + AL L LT ++ +L L LE VT LS C+ + +S A + L+ CNR + +EV+ + V N+ K V E I ++ LL YR +K KG +IF TC LL +L+K +N + S + D + S Y+ L++ + N+++IL + + N S + F P + + + ++L L+ +N+
Sbjct: 1561 RAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQ--------------------RYNKLRHSVIYIQAIFRGKKAR-RHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIK-IQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQ-----RHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----------------AKHKLYQFLHLRK--AAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRK-LETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRA-FLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTK----IKAIRLSLQVVNREIREENKLYKRTALALHYL----LTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIFVLIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLK-----TTNRASDVRSRSKVVDRIYSLYK--LTAHKHKM-----NTERILYKQKKNSSISIP--FIPETPVRTRIVSRLKPDWVLRRDNME 3457
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Human
Match: ASPM (abnormal spindle microtubule assembly [Source:HGNC Symbol;Acc:HGNC:19048]) HSP 1 Score: 271.937 bits (694), Expect = 1.647e-73 Identity = 256/903 (28.35%), Postives = 411/903 (45.51%), Query Frame = 1
Query: 712 ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLF----------------------------ENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT------------------------SANLFDKE-------ILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKM---------KKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK------KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVVHKVLF-KRKLEKRLR--------------SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQ-KNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKK 3114
A +L SE V AI+K+ E+ L KD +K + + +++YN WL + + +SL N++ FI ++LWN DIA ++R + + +L++ L++ L +V LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + L V+H+QT DE+DF V+NL+ D+ GVRL R ++L N D+ KLR PA+ +K N+++ ++ K G + G I I HREKTL LLW + +D ++ D+L EI ++ + +LL+ WV +VC YN V N + + DGR C LIH+Y P Y+ + I TT T S FD E LLENEK+NF + S ++ +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ K H K I+Q V FL ++ + ++ Q +R LA+ ++ + K+A LIQ +RRY + K+K+A + Q+ +R + K YL I +++ IIQ L R+ + +R S IIQ+ + L K +K +A +IQ+ +RGY R+ + Q AA+IIQ + R+ R Y+ +KS +I+Q +V L KR LE+R + + + IQ+ + ++ +N K ++V ++ +F L+ K+F++ +S+ ++ + LS RN A +IQ VR + R+K + + I IQ +R YS RKK
Sbjct: 19 ACRLFTSEKMVKAIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGE--LISLEDNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYAKISRLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRH-QEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQAMWRRYRAKKYLCKVKAACKI-QAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRN-----------------------------RAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKK 888 HSP 2 Score: 102.064 bits (253), Expect = 9.495e-21 Identity = 145/560 (25.89%), Postives = 255/560 (45.54%), Query Frame = 1
Query: 5329 KQKKAVINIQKNFRRF---SELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFL-AKRSYQRNLSI-----IIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY----------------CLLK--SYTLLIQQRWRFIVLKR------SAVV-IQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSE-FIKLVKNLL--YRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKS 6873
K+ +A IQ +R++ ++LK Q + A+ IIQ ++ ++ +K+ + IQ Y RR + K M+K L ++ K L+ + + RA ++L K+ IQ++YR +K Y + +++ +IQ + R RFL ++++ IIIQ+ +R L AK +++ L I +Q+ RG + + + ++A ++IQK ++ KH +I +KS + LQ +RG+L+RK FL+ + ++ N + + + A +N K++ + I IQ +FR +Q++R+ CL + +IQ+ R +L++ S ++ IQ +WRG R K +I IR NR + N + AL L LT ++ +L L LE VT LS C+ + +S A + L+ CNR + +EV+ + V N+ K V E I ++ LL YR +K KG +IF TC LL +L+K ++
Sbjct: 515 KEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQN-----------KAASLIQAMWRRYRAK----KYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWR----KKNDCTKIKAIRLSLQVVNREIREENKLYKRTALALHYL----LTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIFVLIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRA 1051 HSP 3 Score: 100.523 bits (249), Expect = 3.320e-20 Identity = 111/452 (24.56%), Postives = 204/452 (45.13%), Query Frame = 1
Query: 3511 LLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQK---------EMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKK 4839
LL R+ I+ + + RK++ + K+ +AA ++Q +++ K++ RK + VIQKY RR++ +++ + K L+Q+ R KK Y K+ A I + + + A K+YL+ +V +IQ F + R FL+++ SAI+IQ+ R + KI IK H++A LIQ YR YK R+ F+ +++AA++IQK YIR + +++ KY + KK+ +Q + +G+++RK+++ QR ++ F + Y L A IQ+ + YL K + +V IQ ++RA FI + ++ K++ + L ++N + ++Q ++ F+ RK +K S I +Q ++RG++ KK
Sbjct: 510 LLDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQAMWRRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIK-----------------RHRAACLIQAHYRGYKGRQVFLRQKSAALIIQK-----YIRAREAGKHERI--------------KYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLH----------------------------FTAAAYYH---LNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAAS-----VIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKK 888 HSP 4 Score: 94.7449 bits (234), Expect = 2.109e-18 Identity = 110/406 (27.09%), Postives = 191/406 (47.04%), Query Frame = 1
Query: 4858 ASICIQKNVRRY---CQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRID---------LEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFT------HRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVR---LKYKKIIKLVVFIQKN-IRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRK 6009
A+ IQ R+Y +K +++ A+ +IQ V FL + + ++++ AA+++Q+++R+ L R++ ++ KAA +IQ +R Y + +LC+ + IQ +++ + K+YL I + IQ + R RFL ++ S IIIQ+ R H +K+ +A IQ ++R + + F K+A++IIQK YI +E K + K+ K +T+I+Q +RG VR L+ + I+L+ F N VR IQ Y+++ KN S+ IQ+ R + KRF++ +I I+ + L++R+ R S+I Q VR L + K +K + I IQ +GY RK
Sbjct: 519 AARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQAMWRRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQK----YIRAREAGKHER---------------IKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVR------------IQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRN--RAASVI---QKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK 887 HSP 5 Score: 79.337 bits (194), Expect = 8.708e-14 Identity = 117/416 (28.12%), Postives = 186/416 (44.71%), Query Frame = 1
Query: 3064 AAIIIQKTFRCYSVR---KKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVX---------XXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQK--YIKMHQCRQKFLKLKSQVITIQKNIRALLQRR------RYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFR----KMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMI-ITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTT------AIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQ 4218
AA +IQ T+R Y ++ K+ + +A +IQ V + + ++ K + LVIQK+ + L + K K + Q++ R+Y +K KV K+ IQ +R A K++L K ++Q Y K+ R +FL +++ I IQ+ RA+L + IK +A IQ +R K ++ + AA ++QKY ++ K R + K+S ++Q R + RK+F ++ ++KIR++ T Y A + I + K Y A K +SVI IQ FR + K F IQKY IK+ + Q A VIQK +R FL+RK IQ +R Y RK C + AI + Q IR++
Sbjct: 519 AARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQAMWRRYRAKKYLCKV-KAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLE--RTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQ-------RAKIRLLHFTAAAYYHLNA--VRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRF---------IQKY--HSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVNREIREE 911 HSP 6 Score: 78.1814 bits (191), Expect = 1.959e-13 Identity = 115/402 (28.61%), Postives = 174/402 (43.28%), Query Frame = 1
Query: 4030 AIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFI---------CKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSH----FICQKNAAIKLQKNIRGYLIRKNFTETRNKIIL---------------VQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQ 5151
A ++IQ + FL ++ L +A +IQ ++R ++ + + AA +IQ +R+ Y ++Y K IQ+ R + A ++Y + KA IQ + R +++ R SA+IIQ+ R L K FLM ++ AA LIQ RGY R+ + ++ A IIQ + RA H +I K + + LQ +RG+L+RK F E R KI L +Q K ++A K K +S I +Q+ FR K+F++ K SI K + Q L + R AS VIQK VR FL R K Q + + II IQ +RGY+ R +KN C I+
Sbjct: 545 AARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQAMWRR-YRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAH-------------EHFLMIKRHR----AACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQ-KYHSI---KKIEHEGQECLSQRNRAAS-VIQKAVRHFLLR-KKQEKFTSGIIK----------------------IQALWRGYSWR-----KKNDCTKIK 895 HSP 7 Score: 67.781 bits (164), Expect = 2.762e-10 Identity = 109/416 (26.20%), Postives = 190/416 (45.67%), Query Frame = 1
Query: 2572 QIKAAVIIQSFYRSSVCR---RTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSI----ICQKNYLKIK--QSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQ----YLKVRKSTIIIQKHFRAISARKQFLNFRK------FT---------IVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQ 3735
+I+AA +IQ+ +R + + + K+ IIQ V L K++L KR+ + ++IQKY R +L Q+ L ML ++ K+A +IQ ++RY AKK ++ K A IQ R +++ + A IIQ F R +FL SAI+IQ+ R+I I +++L IK ++ +IQ H +G+ ++ + + +I Q +R K Y++ +KST+I+Q R RK+FL R FT + +Q+ K++ + K + VI IQ+ RA LQ +R+I+ ++ I+ + + C ++ N+AA+V+QK + ++ +K+ K + IQ R RK+
Sbjct: 516 EIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRR-------------------------------------VLAQRKLLMLKKEKLEKVQNKAASLIQAMWRRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQR-----NRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKK 888 HSP 8 Score: 60.077 bits (144), Expect = 6.325e-8 Identity = 51/169 (30.18%), Postives = 87/169 (51.48%), Query Frame = 1
Query: 2080 FIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYA-KRRNYTIQIKA 2583
+I K +I+Q++VR +L K+F + +I + Y +A+ IQ+ Y+ YL K ++ + +Q FR L +K +++ Y SI I++ G C S R + +IQK V+ +L RKK K T I+ IQ+ +RGY+ +++N +IKA
Sbjct: 741 YIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAY--------YHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHE--GQECLSQRNR---AASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKA 896
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Human
Match: ASPM (abnormal spindle microtubule assembly [Source:HGNC Symbol;Acc:HGNC:19048]) HSP 1 Score: 269.626 bits (688), Expect = 1.141e-71 Identity = 270/980 (27.55%), Postives = 430/980 (43.88%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTH--LSKTKVEDIN----------------KNMPIYIE------------------ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLF----------------------------ENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT------------------------SANLFDKE-------ILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISK---------MKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK------KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVVHKVLF-KRKLEKRLR--------------SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQ-KNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKK 3114
D+ W ++QE F WLN I KT + ++N P E A +L SE V AI+K+ E+ L KD +K + + +++YN WL + + +SL N++ FI ++LWN DIA ++R + + +L++ L++ L +V LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + L V+H+QT DE+DF V+NL+ D+ GVRL R ++L N D+ KLR PA+ +K N+++ ++ K G + G I I HREKTL LLW + +D ++ D+L EI ++ + +LL+ WV +VC YN V N + + DGR C LIH+Y P Y+ + I TT T S FD E LLENEK+NF + S ++ +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ K H K I+Q V FL ++ + ++ Q +R LA+ ++ K+A LIQ +RRY + K+K+A + Q+ +R + K YL I +++ IIQ L R+ + +R S IIQ+ + L K +K +A +IQ+ +RGY R+ + Q AA+IIQ + R+ R Y+ +KS +I+Q +V L KR LE+R + + + IQ+ + ++ +N K ++V ++ +F L+ K+F++ +S+ ++ + LS RN A +IQ VR + R+K + + I IQ +R YS RKK
Sbjct: 692 DERWKEKQEQGFTWWLNFILTPDDFTVKTNISEVNAATLLLGIENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVKAIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGE--LISLEDNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYAKISRLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRH-QEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQAMWRRYRAKKYLCKVKAACKI-QAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRN-----------------------------RAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKK 1638 HSP 2 Score: 102.449 bits (254), Expect = 1.126e-20 Identity = 145/560 (25.89%), Postives = 255/560 (45.54%), Query Frame = 1
Query: 5329 KQKKAVINIQKNFRRF---SELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFL-AKRSYQRNLSI-----IIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY----------------CLLK--SYTLLIQQRWRFIVLKR------SAVV-IQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSE-FIKLVKNLL--YRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKS 6873
K+ +A IQ +R++ ++LK Q + A+ IIQ ++ ++ +K+ + IQ Y RR + K M+K L ++ K L+ + + RA ++L K+ IQ++YR +K Y + +++ +IQ + R RFL ++++ IIIQ+ +R L AK +++ L I +Q+ RG + + + ++A ++IQK ++ KH +I +KS + LQ +RG+L+RK FL+ + ++ N + + + A +N K++ + I IQ +FR +Q++R+ CL + +IQ+ R +L++ S ++ IQ +WRG R K +I IR NR + N + AL L LT ++ +L L LE VT LS C+ + +S A + L+ CNR + +EV+ + V N+ K V E I ++ LL YR +K KG +IF TC LL +L+K ++
Sbjct: 1265 KEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQN-----------KAASLIQAMWRRYRAK----KYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWR----KKNDCTKIKAIRLSLQVVNREIREENKLYKRTALALHYL----LTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIFVLIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRA 1801 HSP 3 Score: 101.293 bits (251), Expect = 2.525e-20 Identity = 111/452 (24.56%), Postives = 204/452 (45.13%), Query Frame = 1
Query: 3511 LLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQK---------EMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKK 4839
LL R+ I+ + + RK++ + K+ +AA ++Q +++ K++ RK + VIQKY RR++ +++ + K L+Q+ R KK Y K+ A I + + + A K+YL+ +V +IQ F + R FL+++ SAI+IQ+ R + KI IK H++A LIQ YR YK R+ F+ +++AA++IQK YIR + +++ KY + KK+ +Q + +G+++RK+++ QR ++ F + Y L A IQ+ + YL K + +V IQ ++RA FI + ++ K++ + L ++N + ++Q ++ F+ RK +K S I +Q ++RG++ KK
Sbjct: 1260 LLDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQAMWRRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIK-----------------RHRAACLIQAHYRGYKGRQVFLRQKSAALIIQK-----YIRAREAGKHERI--------------KYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLH----------------------------FTAAAYYH---LNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAAS-----VIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKK 1638 HSP 4 Score: 96.6709 bits (239), Expect = 5.398e-19 Identity = 110/406 (27.09%), Postives = 191/406 (47.04%), Query Frame = 1
Query: 4858 ASICIQKNVRRY---CQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRID---------LEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFT------HRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVR---LKYKKIIKLVVFIQKN-IRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRK 6009
A+ IQ R+Y +K +++ A+ +IQ V FL + + ++++ AA+++Q+++R+ L R++ ++ KAA +IQ +R Y + +LC+ + IQ +++ + K+YL I + IQ + R RFL ++ S IIIQ+ R H +K+ +A IQ ++R + + F K+A++IIQK YI +E K + K+ K +T+I+Q +RG VR L+ + I+L+ F N VR IQ Y+++ KN S+ IQ+ R + KRF++ +I I+ + L++R+ R S+I Q VR L + K +K + I IQ +GY RK
Sbjct: 1269 AARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQAMWRRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQK----YIRAREAGKHER---------------IKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVR------------IQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRN--RAASVI---QKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK 1637 HSP 5 Score: 80.1073 bits (196), Expect = 5.594e-14 Identity = 117/416 (28.12%), Postives = 186/416 (44.71%), Query Frame = 1
Query: 3064 AAIIIQKTFRCYSVR---KKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVX---------XXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQK--YIKMHQCRQKFLKLKSQVITIQKNIRALLQRR------RYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFR----KMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMI-ITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTT------AIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQ 4218
AA +IQ T+R Y ++ K+ + +A +IQ V + + ++ K + LVIQK+ + L + K K + Q++ R+Y +K KV K+ IQ +R A K++L K ++Q Y K+ R +FL +++ I IQ+ RA+L + IK +A IQ +R K ++ + AA ++QKY ++ K R + K+S ++Q R + RK+F ++ ++KIR++ T Y A + I + K Y A K +SVI IQ FR + K F IQKY IK+ + Q A VIQK +R FL+RK IQ +R Y RK C + AI + Q IR++
Sbjct: 1269 AARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQAMWRRYRAKKYLCKV-KAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLE--RTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQ-------RAKIRLLHFTAAAYYHLNA--VRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRF---------IQKY--HSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVNREIREE 1661 HSP 6 Score: 79.337 bits (194), Expect = 1.213e-13 Identity = 116/416 (27.88%), Postives = 171/416 (41.11%), Query Frame = 1
Query: 3961 SAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSH----FICQKNAAIKLQKNIRGYLIRKNFTETRNKIIL---------------VQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQ 5151
+A+VIQKY R + ++ +N ++A+LIQ +R Y+ +K ++CK AA IQ +R ++Y K V IQ Y +++ R +++ R SA+IIQ+ R L K FLM ++ AA LIQ RGY R+ + ++ A IIQ + RA H +I K + + LQ +RG+L+RK F E R KI L +Q K ++A K K +S I +Q+ FR K+F++ K SI K + Q L + R AS VIQK VR FL R K Q + + II IQ +RGY+ R +KN C I+
Sbjct: 1318 AALVIQKYWRRVLAQRKLLMLKKEKLEKVQN--------------KAASLIQAMWRRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCF--------YTKLE---------------RTRFLNVRASAIIIQRKWRAILPAKIAH-------------EHFLMIKRHR----AACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQ-KYHSI---KKIEHEGQECLSQRNRAAS-VIQKAVRHFLLR-KKQEKFTSGIIK----------------------IQALWRGYSWR-----KKNDCTKIK 1645 HSP 7 Score: 69.3218 bits (168), Expect = 1.291e-10 Identity = 107/417 (25.66%), Postives = 190/417 (45.56%), Query Frame = 1
Query: 2572 QIKAAVIIQSFYRSSVCR---RTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRN-SVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSI----ICQKNYLKIK--QSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQK----QYLKVRKSTIIIQKHFRAISARKQFLNFRK------FTIV---------VQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQ 3735
+I+AA +IQ+ +R + + + K+ IIQ V L K++L KR+ + ++IQKY R +L + L++++ K++N + L+Q R RY AKK ++ K A IQ R +++ + A IIQ F R +FL SAI+IQ+ R+I I +++L IK ++ +IQ H +G+ ++ + + +I Q +R K +Y++ +KST+I+Q R RK+FL R FT +Q+ K++ + K + VI IQ+ RA LQ +R+I+ ++ I+ + + C ++ N+AA+V+QK + ++ +K+ K + IQ R RK+
Sbjct: 1266 EIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWR---------------RVLAQRKLLMLKKEKLEKVQNKAASLIQAMWR-----------------------RYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQR-----NRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKK 1638 HSP 8 Score: 62.7734 bits (151), Expect = 1.294e-8 Identity = 60/211 (28.44%), Postives = 102/211 (48.34%), Query Frame = 1
Query: 2011 YRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLK----KFKSIKMRIIICQSVVKRYLARHRISKMKK---------------SAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYA-KRRNYTIQIKA 2583
+RAA IQ +R Y+ + F+ +I+Q +R K K+ K +I Q++V+ +L R R + + +A+ IQ+ Y+ YL K ++ + +Q FR L +K +++ Y SI I++ G C S R + +IQK V+ +L RKK K T I+ IQ+ +RGY+ +++N +IKA
Sbjct: 1445 HRAACLIQAHYRGYKGRQV----FLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEH--EGQECLSQRNR---AASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKA 1646
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Human
Match: MYO5A (myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]) HSP 1 Score: 75.0998 bits (183), Expect = 1.937e-12 Identity = 51/202 (25.25%), Postives = 106/202 (52.48%), Query Frame = 1
Query: 5143 TIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSE--LKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMI--KSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKN 5736
T +N + ++ K + + IF + Y+ + R +L+ + I IQK RG+ +KY++ +KA I +Q+ R + F A+ IIQK +R Y++R+ +K +R + +QSY+R ++ ++++ I + +IIQK +RG R YK+ + ++++Q R + + +K +++ + ++H +N
Sbjct: 726 TCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMEN 927 HSP 2 Score: 74.3294 bits (181), Expect = 3.670e-12 Identity = 69/260 (26.54%), Postives = 123/260 (47.31%), Query Frame = 1
Query: 2113 QSIVRRFLCLKKFKSI-KMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLAR--KKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKS--VIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQK 2877
Q R+ L K K + R C++V+++ + + K+ I + YL ++R +K+++A + +Q R +L++K YL R+RK+ +Q+YV+GY AR KF++ TKA +IQ +R Y RR Y I+ A +++QS+ R + R Y + + +IIQK V L + ++ + + I +Q R + +R K K +E Y +K + M N ++ LQ+
Sbjct: 704 QEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYL-----------------------RMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY------KKLHIGMENKIMQLQR 934 HSP 3 Score: 71.2478 bits (173), Expect = 2.833e-11 Identity = 54/166 (32.53%), Postives = 82/166 (49.40%), Query Frame = 1
Query: 4921 RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIR--AHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRL--KMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLK 5406
R A I IQK +RG+L R KY R AAI +QR + RGY R A FL + + IQ Y++ Y++R++Y R TI +Q +R +++RNR+ ++ + +IIQK RG+ Y + A+I +Q FRR + + LK
Sbjct: 767 RAACIRIQKTIRGWLLRKKYLRMRKAAITMQR-----------------------YVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLK 909 HSP 4 Score: 68.5514 bits (166), Expect = 1.801e-10 Identity = 50/175 (28.57%), Postives = 94/175 (53.71%), Query Frame = 1
Query: 3466 KLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEK--KQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKY 3984
KL++ I IQK IR L R++Y++ +KA I +QR R + + + + +AAT++QKY++ Y+ +++++ + + V+Q Y R + R +++K IL + K +I +KR V+G+ AR Y H++I +Q FR M ++ +K A +++Y
Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK-----ILREHKA--VIIQKR--------------VRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY 918 HSP 5 Score: 67.781 bits (164), Expect = 3.807e-10 Identity = 46/138 (33.33%), Postives = 78/138 (56.52%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKL---RSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDT--RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRI 5049
A I++QK IRG+L+RK + R I +Q ++G+ AR CY K ++ I+QK +R + +++ + A+I +Q +R + YR + +++IQK VRG+L R Y+R + A I LQ FR+ + R +
Sbjct: 769 ACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQAR-CYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKREL 905 HSP 6 Score: 66.2402 bits (160), Expect = 9.204e-10 Identity = 58/176 (32.95%), Postives = 87/176 (49.43%), Query Frame = 1
Query: 5860 LAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIR--KIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRGRQLRCH 6381
L K YQ + I F V L KL+ K+R A I IQKT++G+ +RK Y ++K+ I +QR++RG+ R FL+ A+ II K+ R +VR + KI R A+I +Q+Y R ++ + RY R I+ + AV+IQ+ RG R H
Sbjct: 736 LDKDKYQFGKTKIFFRAGQV-AYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRY-------KI--------RRAATIVLQSYLRGFLARNRY--------------RKILREHKAVIIQKRVRGWLARTH 881 HSP 7 Score: 66.2402 bits (160), Expect = 1.018e-9 Identity = 58/201 (28.86%), Postives = 93/201 (46.27%), Query Frame = 1
Query: 4681 GYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNA--HKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSV 5277
YL + + R I +Q ++G++ RK Y ++R ++I +Q+ RG+ A + KFL+ A+ IQK R Y + Y+ R A+IV+Q Y+RGFL R +Y++ IL+ H A IIQ RG+ R H+ K S I I++QC RR +++ +LK+
Sbjct: 756 AYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK------ILREH---------------KAVIIQKRVRGWLARTHY---KRSMHAI--------------------IYLQCCFRRMMAKRELKKLKIEA 912 HSP 8 Score: 63.929 bits (154), Expect = 4.548e-9 Identity = 47/169 (27.81%), Postives = 91/169 (53.85%), Query Frame = 1
Query: 4291 KQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYK--RKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHF--ICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLR 4785
+++ A IQK +G+++RKKY+ R++A+ +Q+ YVR + R K R+ AAT+IQK R Y+VR+R + + A ++Q++ R R+ + I +++ A+ +QK +RG+L R ++ + + II +Q + +A++ +KL+
Sbjct: 764 DKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQR-----------------------YVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLK 909 HSP 9 Score: 58.151 bits (139), Expect = 3.043e-7 Identity = 38/110 (34.55%), Postives = 64/110 (58.18%), Query Frame = 1
Query: 4042 IQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIR--KNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQM--KKAATYIQKIAKGYIIRKKY 4359
IQK IRG+L+RK ++A +Q + R Y+ R F+ + AA +IQK +R + +R++Y R I +QS +R F+A +Y+++ + A IQK +G++ R Y
Sbjct: 773 IQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHY 882 HSP 10 Score: 57.3806 bits (137), Expect = 5.528e-7 Identity = 46/171 (26.90%), Postives = 87/171 (50.88%), Query Frame = 1
Query: 5590 RLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYE--YKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLK 6096
+L+ K+ + IQK IR ++R ++L ++K+ I +Q + R + Y + ++ T+IQK R ++ R+R+ ++ I++Q + R FLA+ Y++ ++R A ++IQK V+G+ R HYK ++I LQ R + ++ KLK
Sbjct: 760 KLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK----------ILREHKA-----------VIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLK 909 HSP 11 Score: 56.6102 bits (135), Expect = 8.852e-7 Identity = 55/180 (30.56%), Postives = 88/180 (48.89%), Query Frame = 1
Query: 3304 YLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQ--CRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVV-QKYFKSYICKKQFRKM--KESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQK-KIAA 3825
YL + + K+R + I IQK R RK++L RK I +Q+Y++ +Q C KFL+ IQK R + RRRY K R +AAT+V Q Y + ++ + ++RK+ + +IQK R + R +++ M +I LQ R ++ K+ +K KI A
Sbjct: 757 YLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRY------------KIR------------RAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEA 912 HSP 12 Score: 55.8398 bits (133), Expect = 1.325e-6 Identity = 37/110 (33.64%), Postives = 64/110 (58.18%), Query Frame = 1
Query: 3760 ILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFAR--KKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIY---CSQTTAIKVIQKNIRGFLVR 4074
I +Q IR + +K+Y + A +T+ ++V+GY AR K+L + +IQ +R ++ R+ + + + IV+Q YLRGF+ R Y + A+ +IQK +RG+L R
Sbjct: 771 IRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAV-IIQKRVRGWLAR 879 HSP 13 Score: 53.9138 bits (128), Expect = 5.867e-6 Identity = 40/133 (30.08%), Postives = 70/133 (52.63%), Query Frame = 1
Query: 3952 IKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGF-------LVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNET--RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQ 4323
++ + I IQK +RG++ RK Y A +Q+ +RG+ +R+T ++AT+IQ ++R Y +R+ + +R A IV+Q R R +Y + K + IQ +R ++A YK+ A Y+Q
Sbjct: 766 LRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRT-----KAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQ 893
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Human
Match: MYO5A (myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]) HSP 1 Score: 75.0998 bits (183), Expect = 2.003e-12 Identity = 51/202 (25.25%), Postives = 106/202 (52.48%), Query Frame = 1
Query: 5143 TIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSE--LKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMI--KSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKN 5736
T +N + ++ K + + IF + Y+ + R +L+ + I IQK RG+ +KY++ +KA I +Q+ R + F A+ IIQK +R Y++R+ +K +R + +QSY+R ++ ++++ I + +IIQK +RG R YK+ + ++++Q R + + +K +++ + ++H +N
Sbjct: 726 TCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMEN 927 HSP 2 Score: 74.3294 bits (181), Expect = 3.670e-12 Identity = 69/260 (26.54%), Postives = 123/260 (47.31%), Query Frame = 1
Query: 2113 QSIVRRFLCLKKFKSI-KMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLAR--KKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKS--VIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQK 2877
Q R+ L K K + R C++V+++ + + K+ I + YL ++R +K+++A + +Q R +L++K YL R+RK+ +Q+YV+GY AR KF++ TKA +IQ +R Y RR Y I+ A +++QS+ R + R Y + + +IIQK V L + ++ + + I +Q R + +R K K +E Y +K + M N ++ LQ+
Sbjct: 704 QEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYL-----------------------RMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY------KKLHIGMENKIMQLQR 934 HSP 3 Score: 71.2478 bits (173), Expect = 2.785e-11 Identity = 54/166 (32.53%), Postives = 82/166 (49.40%), Query Frame = 1
Query: 4921 RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIR--AHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRL--KMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLK 5406
R A I IQK +RG+L R KY R AAI +QR + RGY R A FL + + IQ Y++ Y++R++Y R TI +Q +R +++RNR+ ++ + +IIQK RG+ Y + A+I +Q FRR + + LK
Sbjct: 767 RAACIRIQKTIRGWLLRKKYLRMRKAAITMQR-----------------------YVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLK 909 HSP 4 Score: 68.5514 bits (166), Expect = 1.863e-10 Identity = 50/175 (28.57%), Postives = 94/175 (53.71%), Query Frame = 1
Query: 3466 KLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEK--KQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKY 3984
KL++ I IQK IR L R++Y++ +KA I +QR R + + + + +AAT++QKY++ Y+ +++++ + + V+Q Y R + R +++K IL + K +I +KR V+G+ AR Y H++I +Q FR M ++ +K A +++Y
Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK-----ILREHKA--VIIQKR--------------VRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY 918 HSP 5 Score: 67.781 bits (164), Expect = 3.904e-10 Identity = 46/138 (33.33%), Postives = 78/138 (56.52%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKL---RSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDT--RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRI 5049
A I++QK IRG+L+RK + R I +Q ++G+ AR CY K ++ I+QK +R + +++ + A+I +Q +R + YR + +++IQK VRG+L R Y+R + A I LQ FR+ + R +
Sbjct: 769 ACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQAR-CYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKREL 905 HSP 6 Score: 66.2402 bits (160), Expect = 9.051e-10 Identity = 58/176 (32.95%), Postives = 87/176 (49.43%), Query Frame = 1
Query: 5860 LAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIR--KIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRGRQLRCH 6381
L K YQ + I F V L KL+ K+R A I IQKT++G+ +RK Y ++K+ I +QR++RG+ R FL+ A+ II K+ R +VR + KI R A+I +Q+Y R ++ + RY R I+ + AV+IQ+ RG R H
Sbjct: 736 LDKDKYQFGKTKIFFRAGQV-AYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRY-------KI--------RRAATIVLQSYLRGFLARNRY--------------RKILREHKAVIIQKRVRGWLARTH 881 HSP 7 Score: 66.2402 bits (160), Expect = 1.053e-9 Identity = 58/201 (28.86%), Postives = 93/201 (46.27%), Query Frame = 1
Query: 4681 GYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNA--HKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSV 5277
YL + + R I +Q ++G++ RK Y ++R ++I +Q+ RG+ A + KFL+ A+ IQK R Y + Y+ R A+IV+Q Y+RGFL R +Y++ IL+ H A IIQ RG+ R H+ K S I I++QC RR +++ +LK+
Sbjct: 756 AYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK------ILREH---------------KAVIIQKRVRGWLARTHY---KRSMHAI--------------------IYLQCCFRRMMAKRELKKLKIEA 912 HSP 8 Score: 63.929 bits (154), Expect = 4.586e-9 Identity = 47/169 (27.81%), Postives = 91/169 (53.85%), Query Frame = 1
Query: 4291 KQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYK--RKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHF--ICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLR 4785
+++ A IQK +G+++RKKY+ R++A+ +Q+ YVR + R K R+ AAT+IQK R Y+VR+R + + A ++Q++ R R+ + I +++ A+ +QK +RG+L R ++ + + II +Q + +A++ +KL+
Sbjct: 764 DKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQR-----------------------YVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLK 909 HSP 9 Score: 58.151 bits (139), Expect = 2.943e-7 Identity = 38/110 (34.55%), Postives = 64/110 (58.18%), Query Frame = 1
Query: 4042 IQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIR--KNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQM--KKAATYIQKIAKGYIIRKKY 4359
IQK IRG+L+RK ++A +Q + R Y+ R F+ + AA +IQK +R + +R++Y R I +QS +R F+A +Y+++ + A IQK +G++ R Y
Sbjct: 773 IQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHY 882 HSP 10 Score: 56.9954 bits (136), Expect = 5.622e-7 Identity = 46/171 (26.90%), Postives = 87/171 (50.88%), Query Frame = 1
Query: 5590 RLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYE--YKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLK 6096
+L+ K+ + IQK IR ++R ++L ++K+ I +Q + R + Y + ++ T+IQK R ++ R+R+ ++ I++Q + R FLA+ Y++ ++R A ++IQK V+G+ R HYK ++I LQ R + ++ KLK
Sbjct: 760 KLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK----------ILREHKA-----------VIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLK 909 HSP 11 Score: 56.6102 bits (135), Expect = 8.704e-7 Identity = 55/180 (30.56%), Postives = 88/180 (48.89%), Query Frame = 1
Query: 3304 YLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQ--CRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVV-QKYFKSYICKKQFRKM--KESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQK-KIAA 3825
YL + + K+R + I IQK R RK++L RK I +Q+Y++ +Q C KFL+ IQK R + RRRY K R +AAT+V Q Y + ++ + ++RK+ + +IQK R + R +++ M +I LQ R ++ K+ +K KI A
Sbjct: 757 YLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRY------------KIR------------RAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEA 912 HSP 12 Score: 55.8398 bits (133), Expect = 1.348e-6 Identity = 37/110 (33.64%), Postives = 64/110 (58.18%), Query Frame = 1
Query: 3760 ILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFAR--KKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIY---CSQTTAIKVIQKNIRGFLVR 4074
I +Q IR + +K+Y + A +T+ ++V+GY AR K+L + +IQ +R ++ R+ + + + IV+Q YLRGF+ R Y + A+ +IQK +RG+L R
Sbjct: 771 IRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAV-IIQKRVRGWLAR 879 HSP 13 Score: 53.9138 bits (128), Expect = 5.917e-6 Identity = 40/133 (30.08%), Postives = 70/133 (52.63%), Query Frame = 1
Query: 3952 IKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGF-------LVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNET--RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQ 4323
++ + I IQK +RG++ RK Y A +Q+ +RG+ +R+T ++AT+IQ ++R Y +R+ + +R A IV+Q R R +Y + K + IQ +R ++A YK+ A Y+Q
Sbjct: 766 LRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRT-----KAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQ 893
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Celegans
Match: hum-2 (Heavy chain, Unconventional Myosin [Source:UniProtKB/TrEMBL;Acc:A0A168H5A5]) HSP 1 Score: 81.2629 bits (199), Expect = 9.726e-15 Identity = 55/185 (29.73%), Postives = 105/185 (56.76%), Query Frame = 1
Query: 2233 KSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLC--RSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQI---KAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEK---RLRSCIIIQKYIRGFINR 2763
K+ I ++ L R+R + + +A V+Q ++ +L ++ Y + RS+LI+Q +++ +L R Y ++ ++ ++Q V+GYL R+K+ ++ +I+ IQ+ F+ RR Y ++ K+A+ IQ+ +R + RR + RK V+++Q V K L KR+L + RS +QK G N+
Sbjct: 758 KTKIFLRTGQVAVLERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRR-YVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTGLENK 941 HSP 2 Score: 71.2478 bits (173), Expect = 1.082e-11 Identity = 56/178 (31.46%), Postives = 101/178 (56.74%), Query Frame = 1
Query: 2383 IIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLA--RKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVI-IQSFYRSSVCRRTYLNLR--KSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLR 2901
+IQ +G+L R Y+ +R+S I+Q +K +LA R K++++ +A++V+QSA RGY +RR Y QI+ ++I IQ+ ++++ RR LR KS I IQ L +R+ + +++Q +R ++ +R + K +E +G+L +K + N +I LQ L + + R
Sbjct: 785 VIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYE-QIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELK-----IEARSVGHL-QKLNTGLENKIIELQMRLDIANAR 955 HSP 3 Score: 68.5514 bits (166), Expect = 6.943e-11 Identity = 52/204 (25.49%), Postives = 110/204 (53.92%), Query Frame = 1
Query: 3751 KLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFM-YRKM-FLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICK---RNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMK---KAATYIQKIAKG 4338
K I L++ ++ + R AA I K KG+ AR+KY + R S++++Q S + F+ +R++ +L + + IV+Q +RG+++R+ Y + I+ +I G IQ +++ ++R+ ++ K +AI IQ +R + R++ RKKV+ +Q +R+++A ++ +++K ++ ++QK+ G
Sbjct: 758 KTKIFLRTGQVAVLERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKY-------EQIRDSIIG----------------IQAMFKANRVRR-YVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTG 937 HSP 4 Score: 67.0106 bits (162), Expect = 1.986e-10 Identity = 63/291 (21.65%), Postives = 142/291 (48.80%), Query Frame = 1
Query: 5134 SCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYIS--RNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNF-----RRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQ-KNIRANIVRTRFLNIKKSIINIQSFYRMH-------YEYKN-YQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMR 5958
+ IQ +K +L R+KY +R+ + +Q ++ +++ R ++L++ +VI++Q RGY RKY + + ++I IQ F RR+ E ++ ++I IQ +R Y+ R+E RK V +Q +R+++ + + +K + H++ + L+ KII+L + + N R +F K++ ++ M E +N +++++ + ++ C A++ +E K ++ +Q +F + + +I+ + L + K ++ + + R
Sbjct: 782 AATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYE---KSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSV-GHLQKLNTGLE-NKIIELQMRLDIANARTKEEAEKFATASKNLQKTKADLAMMEAERLTLLEARNRVEVLQEEVERLETECDLKEAQRGGMETK--MVELQSRLDQF--QMQSESGQTIVELTEQLEKAKADRVLWDEER 1063 HSP 5 Score: 67.0106 bits (162), Expect = 2.493e-10 Identity = 57/195 (29.23%), Postives = 96/195 (49.23%), Query Frame = 1
Query: 4729 LVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKM---SVIIIQKVTRG 5304
++Q + KGF+AR+ Y+ +R S +IVQ + F A ++ +Y QM A IV+Q VRG+L R KY++ + I +Q F KA R+ R Y + + + S +TIQ ++ YL R++ + R+K + +QC VR+++++ R LK+ SV +QK+ G
Sbjct: 785 VIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRI---------------KYLQM------HRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMF-------------KANRV-----RRYVEKLRY---EKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTG 937 HSP 6 Score: 64.6994 bits (156), Expect = 1.032e-9 Identity = 45/169 (26.63%), Postives = 93/169 (55.03%), Query Frame = 1
Query: 1999 LMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMR--IIICQSVVKRYLARHRISKMKKSAILIQKNY-----RRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIR---KSTKIIQKYVKG 2475
L T AA+ IQ++W+ + Y+T + ++IVQ+ ++ FL ++ K ++M +I+ QS V+ YL R + +++ S I IQ + RRY+ ++RYEK + + +Q+ +R YL ++ + + ++++Q +R +L + + ++ +S +QK G
Sbjct: 776 LDTLAAAATVIQKMWKGFLARRKYET----MRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEK---SAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTG 937 HSP 7 Score: 60.8474 bits (146), Expect = 1.548e-8 Identity = 39/115 (33.91%), Postives = 69/115 (60.00%), Query Frame = 1
Query: 5746 MKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKR--SYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKIL--QKSVIQLQRFIRGFLIRK 6078
+ + TVIQK + F+AR+++ ++ +++I+Q + FLA R Y + +I +QS VRG L + KY+++R + I IQ K +R++ + L +KS I +Q RG+L R+
Sbjct: 779 LAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARR 893 HSP 8 Score: 60.8474 bits (146), Expect = 1.831e-8 Identity = 45/165 (27.27%), Postives = 89/165 (53.94%), Query Frame = 1
Query: 4297 MKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHF--ICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLR 4785
+ AAT IQK+ KG++ R+KY T RRS +I+Q +++ +L+ RR +++ A ++Q RGYL R++ + ++ IQ ++A+ +R + + + +AI +Q RGYL R+ R K+++VQ ++ ++A++ ++L+
Sbjct: 779 LAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLA-----------------FRRIKYLQMHR----AVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELK 922 HSP 9 Score: 58.151 bits (139), Expect = 1.089e-7 Identity = 37/122 (30.33%), Postives = 68/122 (55.74%), Query Frame = 1
Query: 5791 IARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLA--KLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKL--KNASIIISKHVRGVLVR 6144
+ R R + + +IQK ++ FLA+R Y+ ++ VQ+ ++ LA ++KY +M A I++Q V+GY R+ Y+ ++ S+I +Q + +R+ KL + ++I I RG L R
Sbjct: 771 LERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLAR 892 HSP 10 Score: 55.8398 bits (133), Expect = 4.862e-7 Identity = 48/190 (25.26%), Postives = 89/190 (46.84%), Query Frame = 1
Query: 3001 ILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQK--NYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQ 3564
I ++T A+++R + L AA +IQK ++ + R+K+ S +++Q ++++ + + YL++ ++V+V+ QS VR YL +++Y ++R S I IQ F+A R +Y++ L+ + ITIQ R L RR I N+K V+ +Q
Sbjct: 761 IFLRTGQVAVLERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVM-----------------------QSAVRGYLERRKYEQIRDSIIGIQAMFKANRVR--------------RYVEK-------LRYEKSAITIQAAWRGYLARREQIANRKKVVMVQ 906 HSP 11 Score: 55.4546 bits (132), Expect = 7.528e-7 Identity = 40/160 (25.00%), Postives = 79/160 (49.38%), Query Frame = 1
Query: 3616 AATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLIC--RKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKF--SAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTL 4083
AATV+QK +K ++ ++++ M+ S+ ++Q + + R ++ + + VI++QS +R GY R+KY R S+I IQ F+ R+ +++ SAI IQ RG++ R+ + + ++Q +R +L ++ L
Sbjct: 782 AATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVR-----------------------GYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRL 918 HSP 12 Score: 53.5286 bits (127), Expect = 2.463e-6 Identity = 41/140 (29.29%), Postives = 75/140 (53.57%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIA--RKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQ-----KNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRI 5049
AA +QK +G+L R+ + R +++VQ+ +K F+A R Y ++ + I++Q RG+ +K+ +++++ I IQ VRRY + Y ++I IQ RG+L R + +++Q RK+L RR+
Sbjct: 782 AATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRY---EKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRL 918
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Celegans
Match: hum-2 (Heavy chain, Unconventional Myosin [Source:UniProtKB/TrEMBL;Acc:A0A168H5A5]) HSP 1 Score: 81.2629 bits (199), Expect = 9.972e-15 Identity = 55/185 (29.73%), Postives = 105/185 (56.76%), Query Frame = 1
Query: 2233 KSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLC--RSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQI---KAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEK---RLRSCIIIQKYIRGFINR 2763
K+ I ++ L R+R + + +A V+Q ++ +L ++ Y + RS+LI+Q +++ +L R Y ++ ++ ++Q V+GYL R+K+ ++ +I+ IQ+ F+ RR Y ++ K+A+ IQ+ +R + RR + RK V+++Q V K L KR+L + RS +QK G N+
Sbjct: 758 KTKIFLRTGQVAVLERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRR-YVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTGLENK 941 HSP 2 Score: 71.2478 bits (173), Expect = 1.073e-11 Identity = 56/178 (31.46%), Postives = 101/178 (56.74%), Query Frame = 1
Query: 2383 IIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLA--RKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVI-IQSFYRSSVCRRTYLNLR--KSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLR 2901
+IQ +G+L R Y+ +R+S I+Q +K +LA R K++++ +A++V+QSA RGY +RR Y QI+ ++I IQ+ ++++ RR LR KS I IQ L +R+ + +++Q +R ++ +R + K +E +G+L +K + N +I LQ L + + R
Sbjct: 785 VIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYE-QIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELK-----IEARSVGHL-QKLNTGLENKIIELQMRLDIANAR 955 HSP 3 Score: 68.5514 bits (166), Expect = 6.769e-11 Identity = 52/204 (25.49%), Postives = 110/204 (53.92%), Query Frame = 1
Query: 3751 KLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFM-YRKM-FLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICK---RNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMK---KAATYIQKIAKG 4338
K I L++ ++ + R AA I K KG+ AR+KY + R S++++Q S + F+ +R++ +L + + IV+Q +RG+++R+ Y + I+ +I G IQ +++ ++R+ ++ K +AI IQ +R + R++ RKKV+ +Q +R+++A ++ +++K ++ ++QK+ G
Sbjct: 758 KTKIFLRTGQVAVLERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKY-------EQIRDSIIG----------------IQAMFKANRVRR-YVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTG 937 HSP 4 Score: 67.0106 bits (162), Expect = 2.513e-10 Identity = 40/144 (27.78%), Postives = 80/144 (55.56%), Query Frame = 1
Query: 5134 SCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYIS--RNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNF-----RRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIK 5544
+ IQ +K +L R+KY +R+ + +Q ++ +++ R ++L++ +VI++Q RGY RKY + + ++I IQ F RR+ E ++ ++I IQ +R Y+ R+E RK V +Q +R+++ + + +K
Sbjct: 782 AATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYE---KSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELK 922 HSP 5 Score: 66.6254 bits (161), Expect = 2.577e-10 Identity = 57/195 (29.23%), Postives = 96/195 (49.23%), Query Frame = 1
Query: 4729 LVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKM---SVIIIQKVTRG 5304
++Q + KGF+AR+ Y+ +R S +IVQ + F A ++ +Y QM A IV+Q VRG+L R KY++ + I +Q F KA R+ R Y + + + S +TIQ ++ YL R++ + R+K + +QC VR+++++ R LK+ SV +QK+ G
Sbjct: 785 VIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRI---------------KYLQM------HRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMF-------------KANRV-----RRYVEKLRY---EKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTG 937 HSP 6 Score: 64.6994 bits (156), Expect = 1.041e-9 Identity = 45/169 (26.63%), Postives = 93/169 (55.03%), Query Frame = 1
Query: 1999 LMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMR--IIICQSVVKRYLARHRISKMKKSAILIQKNY-----RRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIR---KSTKIIQKYVKG 2475
L T AA+ IQ++W+ + Y+T + ++IVQ+ ++ FL ++ K ++M +I+ QS V+ YL R + +++ S I IQ + RRY+ ++RYEK + + +Q+ +R YL ++ + + ++++Q +R +L + + ++ +S +QK G
Sbjct: 776 LDTLAAAATVIQKMWKGFLARRKYET----MRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEK---SAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTG 937 HSP 7 Score: 60.8474 bits (146), Expect = 1.535e-8 Identity = 39/115 (33.91%), Postives = 69/115 (60.00%), Query Frame = 1
Query: 5746 MKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKR--SYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKIL--QKSVIQLQRFIRGFLIRK 6078
+ + TVIQK + F+AR+++ ++ +++I+Q + FLA R Y + +I +QS VRG L + KY+++R + I IQ K +R++ + L +KS I +Q RG+L R+
Sbjct: 779 LAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARR 893 HSP 8 Score: 60.8474 bits (146), Expect = 1.862e-8 Identity = 45/165 (27.27%), Postives = 89/165 (53.94%), Query Frame = 1
Query: 4297 MKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHF--ICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLR 4785
+ AAT IQK+ KG++ R+KY T RRS +I+Q +++ +L+ RR +++ A ++Q RGYL R++ + ++ IQ ++A+ +R + + + +AI +Q RGYL R+ R K+++VQ ++ ++A++ ++L+
Sbjct: 779 LAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLA-----------------FRRIKYLQMHR----AVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELK 922 HSP 9 Score: 58.151 bits (139), Expect = 1.098e-7 Identity = 37/122 (30.33%), Postives = 68/122 (55.74%), Query Frame = 1
Query: 5791 IARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLA--KLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKL--KNASIIISKHVRGVLVR 6144
+ R R + + +IQK ++ FLA+R Y+ ++ VQ+ ++ LA ++KY +M A I++Q V+GY R+ Y+ ++ S+I +Q + +R+ KL + ++I I RG L R
Sbjct: 771 LERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLAR 892 HSP 10 Score: 55.8398 bits (133), Expect = 5.070e-7 Identity = 48/190 (25.26%), Postives = 89/190 (46.84%), Query Frame = 1
Query: 3001 ILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQK--NYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQ 3564
I ++T A+++R + L AA +IQK ++ + R+K+ S +++Q ++++ + + YL++ ++V+V+ QS VR YL +++Y ++R S I IQ F+A R +Y++ L+ + ITIQ R L RR I N+K V+ +Q
Sbjct: 761 IFLRTGQVAVLERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVM-----------------------QSAVRGYLERRKYEQIRDSIIGIQAMFKANRVR--------------RYVEK-------LRYEKSAITIQAAWRGYLARREQIANRKKVVMVQ 906 HSP 11 Score: 55.4546 bits (132), Expect = 7.590e-7 Identity = 40/160 (25.00%), Postives = 79/160 (49.38%), Query Frame = 1
Query: 3616 AATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLIC--RKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKF--SAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTL 4083
AATV+QK +K ++ ++++ M+ S+ ++Q + + R ++ + + VI++QS +R GY R+KY R S+I IQ F+ R+ +++ SAI IQ RG++ R+ + + ++Q +R +L ++ L
Sbjct: 782 AATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVR-----------------------GYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRL 918 HSP 12 Score: 53.5286 bits (127), Expect = 2.526e-6 Identity = 41/140 (29.29%), Postives = 75/140 (53.57%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIA--RKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQ-----KNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRI 5049
AA +QK +G+L R+ + R +++VQ+ +K F+A R Y ++ + I++Q RG+ +K+ +++++ I IQ VRRY + Y ++I IQ RG+L R + +++Q RK+L RR+
Sbjct: 782 AATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRY---EKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRL 918 HSP 13 Score: 52.7582 bits (125), Expect = 5.075e-6 Identity = 39/165 (23.64%), Postives = 85/165 (51.52%), Query Frame = 1
Query: 5392 FQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFY-----RMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKR 5871
L A+ +IQK ++ ++ R++++ R++ + +Q+ ++ ++ F R+KY ++ + V+ +Q +R + R ++ I+ SII IQ+ + R + E Y+ K +IT IQ R ++AR+ + + ++++Q R++LAKR
Sbjct: 776 LDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLA---------------------FRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYE--KSAIT-IQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKR 916
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Celegans
Match: hum-6 (Unconventional myosin heavy chain 6 [Source:UniProtKB/Swiss-Prot;Acc:P91443]) HSP 1 Score: 53.1434 bits (126), Expect = 3.915e-6 Identity = 36/100 (36.00%), Postives = 55/100 (55.00%), Query Frame = 1
Query: 2425 YKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKL-EKRLRS 2721
Y+ ++ +IQK V+ +L RK F K +A V IQ+A+RG+ +R+ Y I +Q+ RS Y LRK++I Q V L +R++ EKR R
Sbjct: 732 YRILKDKAIVIQKNVRRWLVRKDFEKQRQAAVTIQTAWRGFDQRKRYRQIISGFSRLQAVLRSRQLVSHYQTLRKTIIQFQAVCRGSLVRRQVGEKRKRG 831
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Celegans
Match: hum-7 (Heavy chain, Unconventional Myosin [Source:UniProtKB/TrEMBL;Acc:H2L082]) HSP 1 Score: 52.373 bits (124), Expect = 6.902e-6 Identity = 44/168 (26.19%), Postives = 77/168 (45.83%), Query Frame = 1
Query: 5578 GIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFL-EIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRK 6078
G VR++Y ++ + +N R + V +++ + H N + + + ++ K I I +I +Q++FR LA++ Y R II +Q+L+RG A+ + +K A IQ K Y R+ Y +++SVI LQ RG +RK
Sbjct: 882 GYSVRIEYPSFVQQYRILLRNGRDSTVD-----------DVKEYIHSHASIDNDNIQYGTNKIFMRDAEKLILDDHLHRTIMQSIDTLQRWFRTMLARKRYLRMKEGIIKIQALIRGSFARAEVRKKALAAQTIQCNWKKYKQRQKYLSIRESVIALQSAYRGASVRK 1038
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Celegans
Match: hum-7 (Heavy chain, Unconventional Myosin [Source:UniProtKB/TrEMBL;Acc:H2L082]) HSP 1 Score: 51.9878 bits (123), Expect = 7.252e-6 Identity = 44/168 (26.19%), Postives = 77/168 (45.83%), Query Frame = 1
Query: 5578 GIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFL-EIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRK 6078
G VR++Y ++ + +N R + V +++ + H N + + + ++ K I I +I +Q++FR LA++ Y R II +Q+L+RG A+ + +K A IQ K Y R+ Y +++SVI LQ RG +RK
Sbjct: 882 GYSVRIEYPSFVQQYRILLRNGRDSTVD-----------DVKEYIHSHASIDNDNIQYGTNKIFMRDAEKLILDDHLHRTIMQSIDTLQRWFRTMLARKRYLRMKEGIIKIQALIRGSFARAEVRKKALAAQTIQCNWKKYKQRQKYLSIRESVIALQSAYRGASVRK 1038
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Fly
Match: asp (gene:FBgn0000140 transcript:FBtr0084692) HSP 1 Score: 114.005 bits (284), Expect = 1.504e-24 Identity = 248/1053 (23.55%), Postives = 448/1053 (42.55%), Query Frame = 1
Query: 3943 FLSIKF--SAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKN---FICKRN-AAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTI----RSHFICQKNAAIKLQKNIRGYLI----RKNFTETRNKIILVQSLMKGFIA-RKC---YQKLRSSSIIVQKIFRGFNAHKK-----FLKLKNASICIQKNVRRYCQMKLYRDT----RNASIVIQK--------------YVRGFLCRIKYQRQLLAAIILQRHFRKYL----IIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYL----IRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFR----RFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVK-IQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKN----YQLMKQSITVIQKNCRKF----IARKRFLEIKSNIIIIQKFFRRFL-AKRSYQRNLSIII---FVQSLVRGKL----AKLKYQKMRTATILIQKTVKGYFI----RKHYKILQKSVIQLQRFIRGF----LIRKIFLKLKNASIIISKHVRG----VLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHE-ISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIE---SDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSEFIKLVKNLLYRNINSKRGTKGITIFCHTCLLL 6843
F S KF +A V+QK+ R + ++ VIQ+ IR K L H++AT+IQ +R +++RK F +R AAI++QK R++ ++Q ++ +I IQ R Q++ + + R+++V R +A+ +Q R R ++ +KLLAA ++ R +Q A IQ +R++ + R F+ Q++ + +Q+ +R RK F + + I +Q + ++ RKC Y LRSS + VQ +R + + L+ IC+Q+ +R +M+ R+ RNASI++QK Y+R C I QR+ A + ++R + YL +RI ++ +A R ++ RA FL K + +Q +A L R++YL +R+ TI +Q RR+ + QK R F KY + AV +Q ++R R E +F L+ A+I +Q+ +R R N +K ++SY + +K A + IQ R K + K VV QK +++II +Q YR + E + YQ +Q++ +QK R + + + I+ + + IQ+ +R + A+R + LS I +Q+ +R L + +++ R A ++IQ+ + R+ Y+++Q SVI +QR R R+ F++L+ ++ + + RG + RN FQ + M F QA R ++ ++R+ L + ++ I KR+A VIQR WRG +L ++ H+ + +IR R + + N+VR ++A+ L+ + L L+ L+ ++ + W E + Y I+ + + R D +++ + + NL + + + + +L R + K IF C L+
Sbjct: 967 FRSPKFHAAATVLQKWWR---RHWLHV-------VIQRRIR----HKELMRRHRAATVIQAVFRGHQMRKYVKLFKTERTQAAIILQKFTRRYLAQKQLYQSYHSIITIQRWWR-----------------AQQLGRQH--RQRFVELREAAIFLQ---------------------------RIWRRRLFAKKLLAAAETARLQRSQ-------KQQAAASYIQMQWRSYQLGRIQRQQFLRQRDLIMFVQRRMRSKWSMLEQRKEFQQLKRAAINIQQRWRAKLSMRKCNADYLALRSSVLKVQ-AYRKATIQMRIDRNHYYSLRKNVICLQQRLRAIMKMREQRENYLRLRNASILVQKRYRMRQQMIQDRNAYLRTRKCIINVQRRWRATLQMRRERKNYLHLQTTTKRIQIKFRAKREMKK------QRAEFLQLKKVTLVVQKRRRALLQMRKERQEYLHLREVTIKLQ---RRFHA--------------QKSMR--FMRAKYRGTQAAVSCLQMHWRNHLLRKRERNSFLQLRQAAITLQRRYRA----------RLNMIKQLKSYAQ----------LKQAAITIQTRYRA------KKAMQKQVVLYQKQ-------------REAIIKVQRRYRGNLEMRKQIEVYQKQRQAVIRLQKWWRSIRDMRLCKAGYRRIRLSSLSIQRKWRATVQARRQREIFLSTIRKVRLMQAFIRATLLMRQQRREFEMKRRAAVVIQRRFRARCAMLKARQDYQLIQSSVILVQRKFRANRSMKQARQEFVQLRTIAVHLQQKFRGKRLMIEQRNCFQLLRCSMPGF---------------QARARGFMARKRFQALMTPEMM-----DLIRQKRAAKVIQRYWRG-----YLIRRRQKHQGLLDIRKRIAQLRQEAKAVNSVRCKVQEAVRFLR-GRFIASDALAVLSRLDRLSRTVPHLLMWCSEFMSTFCYGIMAQAI----RSEVDKQLIERCSRIILNLARYNSTTVNTFQEGGLVTIAQMLLRWCD-----KDSEIFNTLCTLI 1852 HSP 2 Score: 112.079 bits (279), Expect = 5.732e-24 Identity = 88/302 (29.14%), Postives = 152/302 (50.33%), Query Frame = 1
Query: 655 HLSKTKVEDINKNMPIYIEATKLLLSE-CKVAIEKINSEVTKDSLKFKDDI-FFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNE-ACFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAK-ILVNIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLW 1548
+L+K ++E + K A +L SE ++ K+ V K +L+ + D R + EL++ +N WL L V + + SN + FI ++ NK ++ R + + E+ ++ ++ L++ L ++ LD AK+ I + LF K S K + ++L F+S L G+I + + H QT +DE+D+ +NL+ D+ DGVRL R+ + IL+ D+ +LR PA+ ++ FN++LA+ A +A + G +I I GHREKTL+LLW
Sbjct: 675 YLTKYRLETLRK------AAVELFFSEQMRLPCSKVAVYVNKQALRIRSDRNLHLDVVMQRTILELLLCFNPLWLRLGLEVVFGE--KIQMQSNRDIVGLSTFILNRLFRNK--CEEQRYSKAYTLTE-EYAETIKKHSLQKILFLLLFLDQAKQKRIVKHNPCLFVKKSPHKETKDILLRFSSELLANIGDITRELRRLGYVLQHRQTFLDEFDYAFNNLAVDLRDGVRLTRVMEVILLRDDLTRQLRVPAISRLQRIFNVKLALGALGEANFQL----GGDIAAQDIVDGHREKTLSLLW 961 HSP 3 Score: 104.375 bits (259), Expect = 1.371e-21 Identity = 216/904 (23.89%), Postives = 401/904 (44.36%), Query Frame = 1
Query: 2581 AAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKS----AVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSL----RNSFLXXXXXXX-XXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSV----RKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRA-ISARK---QFLNFRKFTIVVQKY----IKMHQCRQKFLKLKSQVITIQKNIRALL----QRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMY----RKMFLSIKFSAIVIQKYLRG-----FIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRK--HYIRQ--QYNETRKKVIFIQSLIRQFIAIQK----YKQMKKAATYIQKIAKGYI-IRKK---YVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRF-LMRSVYKRKLLAATLIQKIARGYLVRKR----IVVEQKAVRIIQNFYRAHTI----RSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF----NAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDL--EQKAARIIQNFYRGYTIR 5109
AA ++Q ++R R +L+ V+I +++ HK L +R R+ +IQ RG R+ FK+ A IL+ + YL +KQ + +S+I +Q+ R L R F+ +++AI + + +R FAKK A ++A + K +A AA IQ +R Y + R++FL Q + +Q+ +RS K S+L +K++ +++++ I IQ+ +RA +S RK +L R + VQ Y I+M R + L+ VI +Q+ +RA++ QR Y++ + A I +Q+++R ++Q+I + A Y ++ C I QRR Q ++E K + LQ+ T KR Q K A + K R ++L + +V+Q R + R+ +L ++ I +Q+ F++ K +Q A+ +Q + R L+RK + R +F+ R AAI +Q+++R + I+Q Y + ++ I IQ+ R A+QK Y++ ++A +Q+ +G + +RK+ Y QR++ + +QK R +R L ++ Y+R L++ IQ+ R + +R + + VR++Q F RA + R F ++ AA+ +Q+ R +++K AR+ YQ ++SS I+VQ+ FR A ++F++L+ ++ +Q+ R +L + RN +++ + GF R + + ++ F+ + +DL +++AA++IQ ++RGY IR
Sbjct: 975 AATVLQKWWR-----RHWLH----VVIQRRIRHKELMRRH-----RAATVIQAVFRGHQMRKYVKLFKTERTQAAIILQKFTRRYLAQKQLYQSYHSIITIQRWWRAQQLGRQHRQRFVELREAAIFLQRIWRRRLFAKKLLAAAETARLQRSQKQQA------------AASYIQMQWRSYQLGRIQRQQFLRQRDLIMFVQRRMRS----------KWSMLE--------------------------------QRKEFQQLKRAAINIQQRWRAKLSMRKCNADYLALRSSVLKVQAYRKATIQMRIDRNHYYSLRKNVICLQQRLRAIMKMREQRENYLRLRNASILVQKRYRM---RQQMIQDRNA------YLRTRKC-------------IINVQRRWRATLQMRRERKNYLHLQT------TTKRIQIKFRAKREMKK------QRAEFLQLKKVTLVVQKRRRALLQMRKERQEYLHLREVTIKLQRRFHAQKSMRFMRAKYRGTQA-AVSCLQMHWRNHLLRK-------------------RERNSFLQLRQAAITLQRRYRARLNMIKQLKSYAQLKQAAITIQTRYRAKKAMQKQVVLYQKQREAIIKVQRRYRGNLEMRKQIEVYQKQRQAVIRLQKWWRS--------------------IRDMRLCKAGYRRIRLSSLSIQRKWRATVQARRQREIFLSTIRKVRLMQAFIRATLLMRQQRREFEMKRRAAVVIQRRFRARC----------------AMLK---ARQDYQLIQSSVILVQRKFRANRSMKQARQEFVQLRTIAVHLQQKFR---GKRLMIEQRNCFQLLRCSMPGFQARAR-------GFMARKRFQALMTPEMMDLIRQKRAAKVIQRYWRGYLIR 1707 HSP 4 Score: 94.7449 bits (234), Expect = 1.054e-18 Identity = 187/816 (22.92%), Postives = 360/816 (44.12%), Query Frame = 1
Query: 2008 FYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIR----GYLCRSNYKRIRKSTKIIQK------YVKGYLARKKFVKLTK------AIVVIQSAFRGYA----KRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVVHKVLFKRKLEKR---LRSCII-IQKY----IRGFINRRNFLKFKSAVNILEHYFMGYLR----RKQFLKMRNSVILLQKNLR----MLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQ----RRKFQYLRNAAIIIQKTFRCYSVRKK----FLIQYYSAIVIQKNVRSIIC----QKNYLKIKQSVLVIQKH---TKGFLVXXXXXXXXXXXXXC-QSLVRKYLLQKQ----YLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRA--LLQRR--RYIKNKKAVIFIQRKFRSCKE-KKQIIL---NNQAATVVQKYFKSY----ICKKQFRKMK-ESVTVIQKYQRRLICRKQ---FQKEMKLVILLQSKIRMII----TKKRYQKKIAATLTISKFVKGYF----ARKKYLSYRHSVIVIQNSFRCF----MYRKMFLSIKFSAIVIQKYLRG----FIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNS-----------HHQSATLIQHFYRSYKIRK 4146
F+ AA+ +Q+ WR++ +L+ +++Q +R K + RHR + + + A+ R+Y+ + E+ ++A ++LQ RRYL QK + Y SI+ IQ R G R + +R++ +Q+ + K LA + +L + A IQ +R Y +R+ + Q + +Q RS R+ + L+++ I IQ+ L RK LRS ++ +Q Y I+ I+R ++ + V L+ ++ R+ +L++RN+ IL+QK R M+ RN++L + I +Q + RA +Q R+ + +L+ IQ FR KK FL +V+QK R+++ ++ YL +++ + +Q+ K ++ + + C Q R +LL+K+ +L++R++ I +Q+ +RA + M + + + +LK ITIQ RA +Q++ Y K ++A+I +QR++R E +KQI + QA +QK+++S +CK +R+++ S+++ +K++ + R+Q F ++ V L+Q+ IR + ++ ++ K A + I + + AR+ Y + SVI++Q FR R+ F+ ++ A+ +Q+ RG +R + ++ Q RGF+ RK + ++A +IQ ++R Y IR+
Sbjct: 972 FHAAATVLQKWWRRH---WLH-----------VVIQRRIRH---------------------KELMRRHRAATVIQ-AVFRGHQMRKYVKLFKTERTQAA-IILQKFTRRYLAQKQLYQSYHSIITIQRWWRAQQLGRQHRQRFVELREAAIFLQRIWRRRLFAKKLLAAAETARLQRSQKQQAAASYIQMQWRSYQLGRIQRQQFLRQRDLIMFVQRRMRSKWSMLEQRKEFQQLKRAAINIQQRWRAKLSMRKCNADYLALRSSVLKVQAYRKATIQMRIDRNHYYSLRKNVICLQQRLRAIMKMREQRENYLRLRNASILVQKRYRMRQQMIQDRNAYLRT-----------------------RKCIINVQRRWRATLQMRRERKNYLHLQTTTKRIQIKFRAKREMKKQRAEFLQLKKVTLVVQKRRRALLQMRKERQEYLHLREVTIKLQRRFHAQKSMRFMRAKYRGTQAAVSCLQMHWRNHLLRKRERNSFLQLRQAAITLQRRYRA-------------------RLNMIKQLKSYAQLKQAAITIQTRYRAKKAMQKQVVLYQKQREAIIKVQRRYRGNLEMRKQIEVYQKQRQAVIRLQKWWRSIRDMRLCKAGYRRIRLSSLSIQRKWRATVQARRQREIFLSTIRKVRLMQAFIRATLLMRQQRREFEMKRRAAVVIQRRFRARCAMLKARQDYQLIQSSVILVQRKFRANRSMKQARQEFVQLRTIAVHLQQKFRGKRLMIEQRNCFQLLRCSMPGFQARARGFMARKRFQALMTPEMMDLIRQKRAAKVIQRYWRGYLIRR 1708
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Fly
Match: didum (gene:FBgn0261397 transcript:FBtr0089744) HSP 1 Score: 67.781 bits (164), Expect = 1.486e-10 Identity = 66/254 (25.98%), Postives = 122/254 (48.03%), Query Frame = 1
Query: 2179 CQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTK--IIQKYVKGYLARKKFVKLTKAIVVIQSAFRG-------YAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFL 2913
C+++V +++ + + I + +L ++R K ++QS RR++ ++ +L+I + I IQ + RGYL R +++R++ I+ KY +G+L R+++++L +I IQ+ RG +A R +Y AV IQ F R ++ RR Y +KR R+ II Q IR F+ RR F + K+ + H +++ + N +I +Q+ + L+ NS L
Sbjct: 735 CRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYR-----AVQIQRFVRGALARRAY-----------------------QKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHM------ENKYMGLENKIISMQQRIDELNRDNSNL 954 HSP 2 Score: 61.6178 bits (148), Expect = 1.134e-8 Identity = 54/177 (30.51%), Postives = 98/177 (55.37%), Query Frame = 1
Query: 2170 IIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKS--ATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKI--IQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYT-IQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKV 2685
I I QSVV+R++ R + +++K IQK+ R YL R R +K++ A ++L + R +L ++ YL++ SI IQ RG L R+ + +R + IQ++V+G LAR+ + K + I++ Q+A R + RR + ++ +A I S Y+ L +I +Q+ + ++
Sbjct: 778 ITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTI-------SHMENKYMGLENKIISMQQRIDEL 947 HSP 3 Score: 60.4622 bits (145), Expect = 2.265e-8 Identity = 49/160 (30.63%), Postives = 84/160 (52.50%), Query Frame = 1
Query: 3688 VTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQK--KIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIK--FSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFI 4155
+T++Q RR + R+QF + K++ +Q R + ++R QK + A L +SK+ +G+ R++YL RHS+ IQ R + R F +++ + A+ IQ+++RG + R+ Y + I + Q IR FL R+ A I H Y +N I
Sbjct: 778 ITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYMGLENKI 937 HSP 4 Score: 58.151 bits (139), Expect = 1.265e-7 Identity = 51/164 (31.10%), Postives = 85/164 (51.83%), Query Frame = 1
Query: 3865 RKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIY--CSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNA--AIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYI 4344
RKKY++ ++Q+ R F+YR+ FL I+ IQK+ RG++ R+ + A ++ K RG+L R+ S + IQ + R R F R+ A+ IQ+ R R+ Y + R+ +I Q+ IR+F+A +K+K+MK A I + Y+
Sbjct: 774 RKKYIT------IVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYM 931 HSP 5 Score: 55.0694 bits (131), Expect = 1.152e-6 Identity = 55/234 (23.50%), Postives = 111/234 (47.44%), Query Frame = 1
Query: 4231 RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQR--RSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRN 4926
+K + +QS++R+F+ +++ +++K IQK A+GY+ R++ R R+ +I+ K Y R +L R Y R + + IQ ARG L R + H +R H+ A+++Q+ +RG L R+ + + R II+ Q+ ++ F+AR+ ++++++ + + + K++ L+N I +Q+ + +L RD N
Sbjct: 775 KKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSK-----------------------YARGWLCRRRYLRLRHSISGIQTYARGMLARNKF----------------HAMRDHY-----RAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHM------ENKYMGLENKIISMQQRID-----ELNRDNSN 953 HSP 6 Score: 53.9138 bits (128), Expect = 2.358e-6 Identity = 48/162 (29.63%), Postives = 81/162 (50.00%), Query Frame = 1
Query: 4939 IQKYVRGFLCRIKYQ--RQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNS--CVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSEL-KTFQNLKN 5409
IQK+ RG+L R + Q R+ A +IL ++ R +L RR + + IQ + RG R F ++ V IQ + + L R+ Y + R+ I Q +RR+++R +F R+K I + KY+ + +I++Q+ R EL + NLK+
Sbjct: 804 IQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHM------ENKYMGLENKIISMQQ---RIDELNRDNSNLKH 956
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Fly
Match: didum (gene:FBgn0261397 transcript:FBtr0089745) HSP 1 Score: 67.781 bits (164), Expect = 1.545e-10 Identity = 66/254 (25.98%), Postives = 122/254 (48.03%), Query Frame = 1
Query: 2179 CQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTK--IIQKYVKGYLARKKFVKLTKAIVVIQSAFRG-------YAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFL 2913
C+++V +++ + + I + +L ++R K ++QS RR++ ++ +L+I + I IQ + RGYL R +++R++ I+ KY +G+L R+++++L +I IQ+ RG +A R +Y AV IQ F R ++ RR Y +KR R+ II Q IR F+ RR F + K+ + H +++ + N +I +Q+ + L+ NS L
Sbjct: 735 CRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYR-----AVQIQRFVRGALARRAY-----------------------QKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHM------ENKYMGLENKIISMQQRIDELNRDNSNL 954 HSP 2 Score: 61.6178 bits (148), Expect = 1.154e-8 Identity = 54/177 (30.51%), Postives = 98/177 (55.37%), Query Frame = 1
Query: 2170 IIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKS--ATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKI--IQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYT-IQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKV 2685
I I QSVV+R++ R + +++K IQK+ R YL R R +K++ A ++L + R +L ++ YL++ SI IQ RG L R+ + +R + IQ++V+G LAR+ + K + I++ Q+A R + RR + ++ +A I S Y+ L +I +Q+ + ++
Sbjct: 778 ITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTI-------SHMENKYMGLENKIISMQQRIDEL 947 HSP 3 Score: 60.077 bits (144), Expect = 3.592e-8 Identity = 49/160 (30.63%), Postives = 84/160 (52.50%), Query Frame = 1
Query: 3688 VTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQK--KIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIK--FSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFI 4155
+T++Q RR + R+QF + K++ +Q R + ++R QK + A L +SK+ +G+ R++YL RHS+ IQ R + R F +++ + A+ IQ+++RG + R+ Y + I + Q IR FL R+ A I H Y +N I
Sbjct: 778 ITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYMGLENKI 937 HSP 4 Score: 57.7658 bits (138), Expect = 1.565e-7 Identity = 51/164 (31.10%), Postives = 85/164 (51.83%), Query Frame = 1
Query: 3865 RKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIY--CSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNA--AIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYI 4344
RKKY++ ++Q+ R F+YR+ FL I+ IQK+ RG++ R+ + A ++ K RG+L R+ S + IQ + R R F R+ A+ IQ+ R R+ Y + R+ +I Q+ IR+F+A +K+K+MK A I + Y+
Sbjct: 774 RKKYIT------IVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYM 931 HSP 5 Score: 54.6842 bits (130), Expect = 1.346e-6 Identity = 55/234 (23.50%), Postives = 111/234 (47.44%), Query Frame = 1
Query: 4231 RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQR--RSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRN 4926
+K + +QS++R+F+ +++ +++K IQK A+GY+ R++ R R+ +I+ K Y R +L R Y R + + IQ ARG L R + H +R H+ A+++Q+ +RG L R+ + + R II+ Q+ ++ F+AR+ ++++++ + + + K++ L+N I +Q+ + +L RD N
Sbjct: 775 KKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSK-----------------------YARGWLCRRRYLRLRHSISGIQTYARGMLARNKF----------------HAMRDHY-----RAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHM------ENKYMGLENKIISMQQRID-----ELNRDNSN 953 HSP 6 Score: 53.5286 bits (127), Expect = 3.631e-6 Identity = 48/162 (29.63%), Postives = 81/162 (50.00%), Query Frame = 1
Query: 4939 IQKYVRGFLCRIKYQ--RQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNS--CVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSEL-KTFQNLKN 5409
IQK+ RG+L R + Q R+ A +IL ++ R +L RR + + IQ + RG R F ++ V IQ + + L R+ Y + R+ I Q +RR+++R +F R+K I + KY+ + +I++Q+ R EL + NLK+
Sbjct: 804 IQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHM------ENKYMGLENKIISMQQ---RIDELNRDNSNLKH 956
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Fly
Match: didum (gene:FBgn0261397 transcript:FBtr0089743) HSP 1 Score: 67.781 bits (164), Expect = 1.559e-10 Identity = 66/254 (25.98%), Postives = 122/254 (48.03%), Query Frame = 1
Query: 2179 CQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTK--IIQKYVKGYLARKKFVKLTKAIVVIQSAFRG-------YAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFL 2913
C+++V +++ + + I + +L ++R K ++QS RR++ ++ +L+I + I IQ + RGYL R +++R++ I+ KY +G+L R+++++L +I IQ+ RG +A R +Y AV IQ F R ++ RR Y +KR R+ II Q IR F+ RR F + K+ + H +++ + N +I +Q+ + L+ NS L
Sbjct: 743 CRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYR-----AVQIQRFVRGALARRAY-----------------------QKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHM------ENKYMGLENKIISMQQRIDELNRDNSNL 962 HSP 2 Score: 61.6178 bits (148), Expect = 1.136e-8 Identity = 54/177 (30.51%), Postives = 98/177 (55.37%), Query Frame = 1
Query: 2170 IIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKS--ATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKI--IQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYT-IQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKV 2685
I I QSVV+R++ R + +++K IQK+ R YL R R +K++ A ++L + R +L ++ YL++ SI IQ RG L R+ + +R + IQ++V+G LAR+ + K + I++ Q+A R + RR + ++ +A I S Y+ L +I +Q+ + ++
Sbjct: 786 ITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTI-------SHMENKYMGLENKIISMQQRIDEL 955 HSP 3 Score: 60.077 bits (144), Expect = 3.389e-8 Identity = 49/160 (30.63%), Postives = 84/160 (52.50%), Query Frame = 1
Query: 3688 VTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQK--KIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIK--FSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFI 4155
+T++Q RR + R+QF + K++ +Q R + ++R QK + A L +SK+ +G+ R++YL RHS+ IQ R + R F +++ + A+ IQ+++RG + R+ Y + I + Q IR FL R+ A I H Y +N I
Sbjct: 786 ITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYMGLENKI 945 HSP 4 Score: 58.151 bits (139), Expect = 1.439e-7 Identity = 51/164 (31.10%), Postives = 85/164 (51.83%), Query Frame = 1
Query: 3865 RKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIY--CSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNA--AIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYI 4344
RKKY++ ++Q+ R F+YR+ FL I+ IQK+ RG++ R+ + A ++ K RG+L R+ S + IQ + R R F R+ A+ IQ+ R R+ Y + R+ +I Q+ IR+F+A +K+K+MK A I + Y+
Sbjct: 782 RKKYIT------IVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYM 939 HSP 5 Score: 55.0694 bits (131), Expect = 1.260e-6 Identity = 55/234 (23.50%), Postives = 111/234 (47.44%), Query Frame = 1
Query: 4231 RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQR--RSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRN 4926
+K + +QS++R+F+ +++ +++K IQK A+GY+ R++ R R+ +I+ K Y R +L R Y R + + IQ ARG L R + H +R H+ A+++Q+ +RG L R+ + + R II+ Q+ ++ F+AR+ ++++++ + + + K++ L+N I +Q+ + +L RD N
Sbjct: 783 KKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSK-----------------------YARGWLCRRRYLRLRHSISGIQTYARGMLARNKF----------------HAMRDHY-----RAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHM------ENKYMGLENKIISMQQRID-----ELNRDNSN 961 HSP 6 Score: 53.5286 bits (127), Expect = 3.543e-6 Identity = 48/162 (29.63%), Postives = 81/162 (50.00%), Query Frame = 1
Query: 4939 IQKYVRGFLCRIKYQ--RQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNS--CVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSEL-KTFQNLKN 5409
IQK+ RG+L R + Q R+ A +IL ++ R +L RR + + IQ + RG R F ++ V IQ + + L R+ Y + R+ I Q +RR+++R +F R+K I + KY+ + +I++Q+ R EL + NLK+
Sbjct: 812 IQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHM------ENKYMGLENKIISMQQ---RIDELNRDNSNLKH 964
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Fly
Match: CG14692 (gene:FBgn0037836 transcript:FBtr0347183) HSP 1 Score: 60.077 bits (144), Expect = 3.325e-8 Identity = 43/144 (29.86%), Postives = 69/144 (47.92%), Query Frame = 1
Query: 2245 LIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQK---------NYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIK--------AAVIIQSFYRSSVCR 2625
L + + R + RI Y + + V++Q HFRRYL ++ N + +IL+IQ +R YL + ++ S + + A+ K KA+VVIQ +R Y K++ ++K AA+IIQ YR V R
Sbjct: 175 LAEADQREFSSRISYIQ---SVVIIQRHFRRYLNERKIGRDKDKCNSVDYVAAILLIQRQVRRYLAKKRVAELKNS-----RDAQKADAKPKAADYMKAVVVIQRHYRIYLKKKQEQNRLKHGPVSLATAAIIIQRAYRRMVAR 310
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Zebrafish
Match: aspm (abnormal spindle microtubule assembly [Source:ZFIN;Acc:ZDB-GENE-050208-620]) HSP 1 Score: 609.372 bits (1570), Expect = 8.551e-177 Identity = 559/2117 (26.41%), Postives = 1003/2117 (47.38%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCI-----FNTHLSKTKVEDINKNM----------PIYIE------------------ATKLLLSECKV-AIEKINSEV-TKDSLKFKDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNEA-CFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKIL-VNIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEI------------------------------KLFENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT------------------------------SANLFDKEILLENEKRNFQIFFSKLKQIGGAPIILPKE---NEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVII--VQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKK---------SAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTK---AIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRT----YLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYF----MGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRK----FQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRAL----LQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICR----KQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNET----RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYV----RRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFIC----QKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKL----KNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRR--IDLEQK--AARIIQNFYRGYTIRAHFLCQKNSCVTI------------------------QNYFKAYLIRKKYL----EIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFS----ELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFV----RLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARK----RFLEIKSNIIIIQKFFR----RFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKR 6330
D+ W+++QE F W+N I F TKV ++ M P E A KL SE V AI+++ EV K L KD +K + + +++YN WL + +I + +SL SNN+ FI ++LWN D+A + R + + +L+R L++ + +V LD AK++ + D LF D+ KSS ++L F+ FL GEG + + S+ L+VSH+QT +DE++F V L+ D+ G+RL R+ ++ ++ + KLR PA+ +K N++LA++ K+ G + G ID I GHREKTL LLW ++ ++ ++D ++L EI + FE+P LL+ WV +VC Y++ N + + DGR C LIH+Y P +L EI TT T + D LLENEK NFQ+ + + +GG P ++ E N IP+ + + L+F +RL+DL RAA IQ WR+Y+ L K + H K + +Q++ R+F+ ++ + Q++ + Y AR ++ +KK +A LIQK Y+ + + +K +SA V+Q+ FR++ +K L+ + L IQ R LC+ Y +++ +Q + +G+L R KF L K A VVIQSAFR Y R+ + + AV+IQ ++R+ V R+ Y ++ +V+++Q ++ + + RS ++IQ R F +R+FL K + +L+ + G RK+++ ++++ + +Q R + R + A IIQ +++R+ + F+ K A ++IQ + RA +K + ++ AAII+Q +R +R++ + +A +IQ +R+ +C + +L K + +VIQ+ + F + + + Y+++RK+TI +Q +R R+ + V+Q +MH+ R F+ K I IQ++ RA + Y++ K A + IQ FR K + + ++QAA V+Q +F+ + K++R+ + + +V+Q+ R + + KQ+ I +QS R ++ +K+ +K I K + Y R YL+ R++ I IQ +R + + Q++ R YCS A +Q + RG RK +N ++AT+IQ Y+ Y+ R F + A++VIQ+Q+R H +R++ E ++ + IQ++ R +A + + AAT IQ+ Y RK ++T + + + Q++ R L + + + + R +R +R+ AAT+IQ R ++ R + AV +Q +RA+ I + +K+AA+ LQ RG R+ + ++QS ++ I +Q+LR + VQ+ FR ++ + K+A++ +Q R + + A+ +IQ +VR + +++QR A LQRHFR I+R+ L++K AA I+Q YRG R H L Q + TI Q F+A I ++ + E + + +Q R +R ++ + I+Q R Y ++Y++ K A I+IQ+ +R + + K++ ++ ++++Q +R +R+ + + + V IQSY RR+ + K++ +K + +IIQ H R R Y+ + K + IQ R + +R +++ + IQ+ +RM+ + ++ + + V+Q+ R R ++ ++++ + +Q++FR R LA+RS +QS +R + + ++ K + A I IQ +G+F R Y +Q + +Q++ R + RK F+ ++ A++ + +RG+LV L KR A+IKIQ+ R +IQ++RY L++ L Q +R +V +R
Sbjct: 675 DERWIEKQERGFTWWMNYILTPDDFKVATEVTKVNALSLTMGNDKFNIPKAPTKEEMSFRTYTARQRLNRLRRAACKLFTSEAMVKAIQRLELEVEAKRLLVRKDRHLWKDIGERQKVLNWLISYNPLWLRIGLE-TIYGEL-ISLESNNDVMGLAMFILGRLLWNPDLAAEFRHSKVPHLYRDGHEEALSRFTLKKLILLVCFLDKAKESRLIEHDPCLFCMDAEFKSSKDLLLAFSRDFLSGEGILSRHLSHLGLAVSHVQTPLDEFNFAVKKLAVDLKCGIRLVRVMELFTLDWTLSRKLRIPAISRLQKVHNVDLALQVLKNKGVDLRDEHGANIDSRDIVDGHREKTLNLLWKIIFAFQVEVLLDENQLKEEISFLRKTWRTKQKLASIMANNSVTVSRMKARRAFEHP-----SQKVTLLMDWVNAVCEFYSLKAENFTVSFSDGRILCYLIHHYHPGHLHAEEIQQRTTQTIECGHRGRVELNNSSSDSDCSFENLATMQSESVTVDFRELLENEKSNFQLVNTAVSYLGGVPAMINPEDMSNTIPNEKVVTCYLSFLCARLLDLRNETRAARVIQGAWRRYK---LQKDIALMHEKNLAATKIQALARKFILKRRLIRQNKAAVKIQTLWRGYSAREKLRVLKKERHYALQNAAATLIQKTYKAWRVKNLLKKNRSA-FVIQAAFRKWHAKK-MLERNTAALRIQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFRKEYMALKSASVRIQAMWRGRAERKKISQLHRFAKIIQSNYRRHLEQTRFLQMKRAAVVIQRQYRAFRDGQKVHAEYTKIKRAAIILQSAYRGRRIRQELQRKNKAATLIQSVMRAHMCHQQFLAQKHAAIVIQQQFRAFTFGR-------------------MERSHYMRLRKATITMQAIYRGSKVRQNLKREHQAATVIQAQFRMHKVRIPFVAAKCAAILIQQHYRAYKVGKTVQATYLQMKNAAVVIQSAFRGMKVRNYLRKSHQAAKVIQAHFRGHSQLKKYRRQQWAASVLQQRFRATVTKNAVMKQYAAIKTATICIQSAFRGMVARKQIAEKQKCAKIIQKMYRAYKQRHDYLALRNATIRIQQQYRAVVSAR------------QQHQR-------YCSLRAAAITLQSSYRGLRARKEINRRQKAATVIQAAYKMYRTRVPFQAMKLASLVIQRQYRCHLLRKKARENFLKLKQSAVAIQAIYRGKLARRDLARRHFAATIIQRKYLAYKQRKCFLTLQAAVIFCQQHYRSILLTRHDRKDYLTKRRAVVAIQASFRGMNVRRQIRREHKAATIIQSHVRMRILNLRFQRLRWAVCTVQQRFRANKIMRQEMAALQEKKSAALILQAAYRGKKTRQALKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTVQERFRANRIMRQEMAALQEKKSAALILQAAYRGKKTRQALKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTLQRHFRANKIMRQEMAALQEKKSAALILQAAYRGMKTR-HTLKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTVQQRFRANRIMRQEMAALQEKKSAALILQAAYRGMKTRQTLKQMHQAATIVQATYRAYSGRKRYLEMKCAAIDIQQRYRAVNAAKQQRKSYLKVRQGALVLQACYRGRKVRRNLQLQCQAAVLIQSYFRRHKEMVKYQAMKLSAVIIQSHFRSYIQARADRKNYQHLRKSAIVIQAAFRGHSLRRHLARKQEASVIIQASFRMYQQRSAFKKQRWAARVLQQRFRALKLRDEHVCQYQQVRNAAVCLQRYFRGMKGRELARRS-----KAARTIQSFLRMSVQRQRFMKEKAAAIAIQSAYRGHFARAQYTRMQAGTVLIQKWYRSRKLVQEDRKRFVAVRQATLTLQSALRGMLV----------------RRLAKRRRAAIKIQSVMRMHIQRKRYVTLRASALKFQAHYRMLVAQR 2719 HSP 2 Score: 424.861 bits (1091), Expect = 7.686e-119 Identity = 467/1854 (25.19%), Postives = 844/1854 (45.52%), Query Frame = 1
Query: 2011 YRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFK----SIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYL----VQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFR----GYAKRRNYTIQIKAAVIIQSFYRSSVCRR--------------------------------------------------TYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRR----KQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALI----QRRKFQYLRNAAIIIQKTFRCYSVRKK-----------------------FLIQYYSAIVIQKNVRSIICQK----NYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQ---YLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQ----AATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIR----MIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRG--FIKRKIYCSQT--TAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQ----YNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYL----IRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVR-------RYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLI----RKKYLEIRQKT----------------------IFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFR--------RFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFV----RLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKR----SYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKI----FLKLKNASIIISKHVRGVLVRNHFQKNK-------------QHMKI----------FAQENLRKRLEASIKIQAYFRCYIQKRRYC-----------LLKSY-------TLLIQQRWRFIV-------LKRSAVVIQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK-----AGVLNFDVIGSEFIKLVKNLLYRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSIS 6879
+R+A IQ +R++ + HF+ + I++Q R + KF+ ++K + Q++ + R +IS++ + A +IQ NYRR+L + R+ ++K A VV+Q +R + V Y KI R+ +I+Q+ RG R +R K+ +IQ ++ ++ ++F+ A +VIQ FR G +R +Y KA + +Q+ YR S R+ TYL ++ + ++IQ + + L K ++ +IQ + RG + + + + A ++L+ F + + KQ+ ++ + I +Q R + R KQK A IIQK ++ Y + +++A ++ATI IQ + RA++ Q +++ LR AAI +Q ++R RK+ F +++VIQ+ R + +K N+LK+KQS + IQ +G L ++ + I Q RKYL KQ +L ++ + I Q+H+R+I RK +L R+ + +Q + R++ + IQ ++R + R+ + + AV +Q++FR+ K +Q + Q AA ++Q ++ ++ ++M ++ T+IQ + R I +FQ+ V +Q + R M Q+K +A L + +G R+ + +IQ+ R + F ++++ +Q++ R +++++ Q +A ++Q RG R TL HQ+AT+IQ R + F R A +Q++FR + I +Q E + + +Q+ R Q KQM +AAT +Q + Y RK+Y+ + +A+ IQ+ R + K R Y + A ++Q RG VR+ + ++ +A +IQ+++R H + K +A+ +Q + R Y+ RKN+ R I++Q+ +G R+ + + +S+I+Q FR + F K + A+ +Q+ R CQ Y+ RNA++ +Q+Y RG R + R+ AA +Q R + +R E+ AA IQ+ YRG+ RA + + V IQ ++++ + RK+++ +RQ T I IQ ++R +I R R++ L+ S + Q R RKY + + A + +QK++R R S LKT QN+K +Q R +I K F++ R + IQ+ R I +F +K L+IQKH R + R K+ ++ + V IQ+ RA R + + + + IQ+++R +NY L + + I++ + R +FL ++ ++ +IQ+ +R L+ R + + + +I++Q+L RG+ + QK TA + IQ +G R+ Y + + I LQR R + ++ + NA+I I RG L R ++ H+ +A ++ +K++ + + IQ FR +Q+++Y ++S+ +IQ R ++ L+R + Q +WRG C IS +R R E N+R + + + ALT L + A +L L LE T LS E C+ L+ES A + L+ CNR V +E+++ I V NL K V + D + L++ +YR K KG +IF TC LLVLL++ E++++
Sbjct: 1490 HRSALVIQTAFRRFTA----QRHFLCLKRSAIVLQQRYRAKVHGGKFRKEYMALKSASVRIQAMWRGRAERKKISQLHRFAKIIQSNYRRHLEQTRFLQMKRAAVVIQRQYRAFRDGQKVHAEYTKIKRAAIILQSAYRGRRIRQELQRKNKAATLIQSVMRAHMCHQQFLAQKHAAIVIQQQFRAFTFGRMERSHYMRLRKATITMQAIYRGSKVRQNLKREHQAATVIQAQFRMHKVRIPFVAAKCAAILIQQHYRAYKVGKTVQATYLQMKNAAVVIQSAFRGMKVRNYLRKSHQAAKVIQAHFRGHSQLKKYRRQQWAASVLQQRFRATVTKNAVMKQYAAIKTATICIQSAFRGMVARKQIAEKQKCAKIIQKMYRAYKQRHDYLALRNATIRIQQQYRAVVSARQQHQRYCSLRAAAITLQSSYRGLRARKEINRRQKAATVIQAAYKMYRTRVPFQAMKLASLVIQRQYRCHLLRKKARENFLKLKQSAVAIQAIYRGKLARRDLARRHFAATIIQ---RKYLAYKQRKCFLTLQAAVIFCQQHYRSILLTRHDRKDYLTKRRAVVAIQASFRGMNVRRQIRREHKAATIIQSHVRMRILNLRFQRLRWAVCTVQQRFRANKIMRQEMAALQEKKSAALILQAAYRGKKTRQALKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTVQERFRANRIMRQEMAALQEKKSAALILQAAYRGKKTRQALKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTLQRHFRANKIMRQEMAALQEKKSAALILQAAYRGMKTRHTLKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTVQQRFRANRIMRQEMAALQEKKSAALILQAAYRGMKTRQTLKQMHQAATIVQATYRAYSGRKRYLEMKCAAIDIQQRYRAVNAAKQ-------------------QRKSYLKVRQGALVLQACYRGRKVRRNLQLQCQAAVLIQSYFRRHKEMVKYQAMKLSAVIIQSHFRSYIQARADRKNYQHLRKSAIVIQAAFRGHSLRRHLARKQEASVIIQASFRMYQQRSAFKKQRWAARVLQQRFRALKLRDEHVCQ---YQQVRNAAVCLQRYFRGMKGR-ELARRSKAARTIQSFLRMSVQRQRFMKEKAAAIAIQSAYRGHFARAQYTRMQAGTVLIQKWYRSRKLVQEDRKRFVAVRQATLTLQSALRGMLVRRLAKRRRAAIKIQSVMRMHIQRKRYVTLRASALKFQAHYRMLVAQRKYRRLQAATVTLQKHYRSHRATLEQRCSYLKTLQNIKK----LQARVRGHIAYKRFQRLRTCAITIQANYRGMIERRRFHQLKECALVIQKHYRAFILCQKERSKFLQLRQSAVVIQRAYRAYQKRQNAMKAQ-AALKIQAWFRGRLARRNYILKQAASATIRRCIQARRQRSKFLAVQHSVRVIQQRWRETLSSRKQHAEFLKLIKSVIYIQALWRGRRLRDSIQKQATAAVKIQSAFRGSIQRRRYHQQRNAAITLQRHFRVLRLARVKEENLRRRHNAAIYIQALWRGWLARQQVKEMAFAARRLRFTAAVYHHLSAIKIQRAVRAHWALKSAKKKISSVLYIQQCFRAKLQRKKYLKDREDIIKTQRAVRSWLHRRNQAASIIQHAVRKLLFRRRKERLQRGIIRAQALWRGH---CSRKLHDTNKVIS-MRQRLREVNQRVKEEDKLCNKTTTALTYLLGLQ-NYAFILAALKHLETATRLSPECCERLVESGATHTIFTLIRSCNRSVPSMEIITLSIQVLLNLSKYHRTIDAVYDVDNSVETLLDLLQ--IYREKAGDKVADKGGSIFTKTCFLLVLLVQDERRAME 3301 HSP 3 Score: 387.111 bits (993), Expect = 2.765e-107 Identity = 407/1615 (25.20%), Postives = 738/1615 (45.70%), Query Frame = 1
Query: 1984 SRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQ----SIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYL----VQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRR----NYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGF----INRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRA-----LIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALL----QRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRH-SVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQ----YNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKN------VRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFIC----QKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLR---------------------------SSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLC----RIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYL----IRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFR----RFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIV----RTRFLNIKKSI----------------------INIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLA----KRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTL-----------------------LIQQRWR-----------FIVLKRSAVVIQRIWRGRQLR 6375
S+ +L + A+ IQ +R Y L + + +++Q + V+R K++ IK +++ Q+ + + R +++ +SA++IQ +RR+ + + +K + +VLQ +R + +K Y+ + + + IQ RG R ++ + KIIQ + +L + +F+++ +A VVIQ +R + + YT +AA+I+QS YR R+ K+ +IQ V+ + ++ + + I+IQ+ R F + R ++++ + A ++ + G R+ + + ++Q RM +R FVA K A ILIQ RA +Q Q ++NAA++IQ FR VR + +A VIQ + R K Y + + + V+Q+ + + V K + KQY ++ +TI IQ FR + ARKQ +K ++QK + ++ R +L L++ I IQ+ RA++ Q +RY + A I +Q +R + +K+I +AATV+Q +K Y + F+ MK + VIQ+ R + RK+ ++ + K + + I +G AR+ L+ RH + +IQ + + RK FL+++ + I Q++ R + RK Y ++ A+ IQ + RG VR+ + H++AT+IQ R + F R A +Q++FR + I +Q E + + +Q+ R Q KQM +AAT IQ + I+ ++ R + +Q+ +RQ ++ + + I+ ++ R K+ AAT+IQ R ++ R + AV +Q +RA+ I + +K+AA+ LQ RG R + ++QS ++ I +Q+LR S+++I+Q +RG + ++ A+ +Q R Y K Y + + A+I IQ+ R R Y + A++LQ +R + R + L+ +AA +IQ+++R + + K S V IQ++F++Y+ RK Y +R+ I IQ R + R R + + +IIQ R Y + KQ+ A +Q+ FR R + +Q ++NA++ +Q+ FR R E ++ K IQS++R + +F K+A + IQ RG F R +Y ++ V IQK R+ + R RF+ ++++ I IQS RMH + K Y ++ S Q + R +A++++ +++ + +QK +R A + SY + L I +Q+ VRG +A ++Q++RT I IQ +G R+ + L++ + +Q+ R F++ R FL+L+ ++++I + R +QK + MK +A++KIQA+FR + +R Y L ++ + +IQQRWR F+ L +S + IQ +WRGR+LR
Sbjct: 1408 SKFQNLKKRHHASVVIQSAFRAY----LIRKELSKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFRKEYMALKSASVRIQAMWRGRAERKKISQLHRFAKIIQSNYRRHLEQTRFLQMKRAAVVIQRQYRAFRDGQKVHAEYTKIKRAAIILQSAYRGRRIRQELQRKNKAATLIQSVMRAHMCHQQFLAQKHAAIVIQQQFRAFTFGRMERSHYMRLRKATITMQAIYRGSKVRQNLKREHQAATVIQAQFRMHKVRIP-----------------------FVAAKCAAILIQQHYRAYKVGKTVQATYLQ-MKNAAVVIQSAFRGMKVRNYLRKSHQAAKVIQAHFRGHSQLKKYRRQQWAASVLQQRFR-------------------ATVTKNAVMKQYAAIKTATICIQSAFRGMVARKQIAEKQKCAKIIQKMYRAYKQRHDYLALRNATIRIQQQYRAVVSARQQHQRYCSLRAAAITLQSSYRGLRARKEINRRQKAATVIQAAYKMYRTRVPFQAMKLASLVIQRQYRCHLLRKK-------------------ARENFLKLKQSAVAIQAIYRGKLARRD-LARRHFAATIIQRKYLAYKQRKCFLTLQAAVIFCQQHYRSILLTRHDRKDYLTKRRAVVAIQASFRGMNVRRQIRREHKAATIIQSHVRMRILNLRFQRLRWAVCTVQQRFRANKIMRQEMAALQEKKSAALILQAAYRGKKTRQALKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTVQERFRANRIMRQEMAALQEKKSAALILQAAYRGKK--TRQALKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTLQRHFRANKIMRQEMAALQEKKSAALILQAAYRGMKTRHTLKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTVQQRFRANRIMRQEMAALQEKKSAALILQAAYRGMKTRQTLKQMHQAATIVQATYRAYSGRKRYLEMKCAAIDIQQRYRAVNAAKQQRKSYLKVRQGALVLQACYRGRKVRRNLQLQCQAAVLIQSYFRRHKEMVKYQAMKLSAVIIQSHFRSYIQARADRKNYQHLRKSAIVIQAAFRGHSLRRHLARKQEASVIIQASFRMYQQRSAFKKQRWAARVLQQRFRALKLRDEHVCQYQQVRNAAVCLQRYFRGMKGR-ELARRSKAARTIQSFLRMSVQRQRFMKEKAAAIAIQSAYRGHFARAQYTRMQAGTVLIQKWYRSRKLVQEDRKRFVAVRQATLTLQSALRGMLVRRLAKRRRAAIKIQSVMRMHIQRKRYVTLRASALKFQAHYRMLVAQRKYRRLQAATVTLQKHYRSHRATLEQRCSYLKTLQNIKKLQARVRGHIAYKRFQRLRTCAITIQANYRGMIERRRFHQLKECALVIQKHYRAFILCQKERSKFLQLRQSAVVIQRAYRA------YQKRQNAMKA----------QAALKIQAWFRGRLARRNYILKQAASATIRRCIQARRQRSKFLAVQHSVRVIQQRWRETLSSRKQHAEFLKLIKSVIYIQALWRGRRLR 2936
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Zebrafish
Match: CR628370.1 (pep chromosome:GRCz11:CHR_ALT_CTG22_1_10:23552945:23582232:1 gene:ENSDARG00000115607.1 transcript:ENSDART00000191456.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR628370.1) HSP 1 Score: 299.286 bits (765), Expect = 4.968e-83 Identity = 235/825 (28.48%), Postives = 411/825 (49.82%), Query Frame = 1
Query: 712 ATKLLLSECKV-AIEKINSEV-TKDSLKFKDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNEA-CFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKIL-VNIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVL---------------------SRHYIDAVIDRDKL-ISEIKL---FENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT------------------------SANLFDKEILLENEKRNFQIFFSKLKQIGGAPIILPKE---NEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVII--VQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKK--------------------SAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQ---KNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK----KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQK----VVH-----KVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLR 2901
A KL SE V AI+++ EV K L KD +K + + +++YN WL + +I + +SL SNN+ FI ++LWN D+A + R + + +L+R L++ + +V LD AK++ + D LF D+ KSS ++L F+ FL GEG + + S+ L+VSH+QT +DE++F V L+ D+ G+RL R+ ++ ++ + KLR PA+ +K N++LA++ K+ G + G ID I GHREKTL LLW ++ ++ + +++ + + +S +K FE+P LL+ WV +VC Y++ N + + DGR C LIH+Y P +L EI TT T A + + LLENEK NFQ+ + + +GG P ++ E N IP+ + + L+F +RL+DL RAA IQ WR+Y+ L K + H K + +Q++ R+F+ ++ ++ Q++ + Y AR ++ + K +A+ IQ YR LC+ +Y ++K V +Q+ FR +L + +N K + + ++IQ+ R YL R +++++ +IQ++ + + RK ++ ++ A++V+Q+AFRG+ R++ ++A++IQ+ +R +R +L L++S I++Q+ VH K ++K+ + R IIQ R + + FL+ K A + G+ RK L N VI +++ LR ++ R
Sbjct: 19 ACKLFTSEAMVKAIQRLELEVEAKRLLVRKDRHLWKDIGERQKVLNWLISYNPLWLRIGLE-TIYGEL-ISLESNNDVMGLAMFILGRLLWNPDLAAEFRHSKVPHLYRDGHEEALSRFTLKKLILLVCFLDKAKESRLIEHDPCLFCMDAEFKSSKDLLLAFSRDFLSGEGILSRHLSHLGLAVSHVQTPLDEFNFAVKKLAVDLKCGIRLVRVMELFTLDWTLSRKLRIPAISRLQKVHNVDLALQVLKNKGVDLRDEHGANIDSRDIVDGHREKTLNLLWKIIFAFQVSNQLKEEISFLRKTWRTKQKLASIMANNSVTVSRMKARQAFEHP-----SQKVTLLMDWVNAVCEFYSLKAENFTVSFSDGRILCYLIHHYHPGHLHAEEIQQRTTQTIECGHRGRVELNNSSSDSDCSFENLATMQSGKELLENEKSNFQLVNTAVSYLGGVPAMINPEDMSNTIPNEKVVTCYLSFLCARLLDLRNETRAARVIQGAWRRYK---LQKDIALMHEKNLAATKIQALARKFILKRRLIRQNKAAVVIQTLWRGYSAREKVKNLLKKNRSAAFRKWHAKKMLERNTAALRIQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFWKEYMRKKISQLHRFAKIIQSNYRRHLEQTRFLQMKRAA-----LWRGHCSRK--LHDTNKVISMRQRLREVNQR 826 HSP 2 Score: 135.961 bits (341), Expect = 3.027e-31 Identity = 138/538 (25.65%), Postives = 247/538 (45.91%), Query Frame = 1
Query: 5377 SELKTFQNLKNASIIIQKNFRCYILRKE---FKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIK--------------------LVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMK---QSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLE-----ASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK-----AGVLNFDVIGSEFIKLVKNLLYRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSIS 6879
+ L +N A+ +IQ +R Y L+K+ +K KIQ+ R++I + A ++IQ RG R K K ++K + IQ R + + ++L +K+ + +Q+++R H + +Q +K + VIQ R ++ RK ++K N ++IQ++FR + +++ Q+ +Y ++++A +++Q +G+ +RK +S + +Q R F ++ FL LK ++I++ + R K H F +E +RK++ A I IQ+ +R ++++ R F+ +KR+A +WRG R + K+ IS +R R E N+R + + + ALT L + A +L L LE T LS E C+ L+ES A + L+ CNR V +E+++ I V NL K V + D + L++ +YR K KG +IF TC LLVLL++ E++++
Sbjct: 493 ARLLDLRNETRAARVIQGAWRRYKLQKDIALMHEKNLAATKIQALARKFILKRRLIRQNKAAVVIQTLWRGYSAREKVKNLLKKNRSAAFRKWHAKKMLERNTAALRIQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFRACVQRKAEQK-------------------RYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRA----------KVHGGKFWKEYMRKKISQLHRFAKI-IQSNYRRHLEQTR----------------FLQMKRAA-----LWRGHCSRKLHDTNKV---IS-MRQRLREVNQRVKEEDKLCNKTTTALTYLLGLQ-NYAFILAALKHLETATRLSPECCERLVESGATHTIFTLIRSCNRSVPSMEIITLSIQVLLNLSKYHRTIDAVYDVDNSVETLLDLLQ--IYREKAGDKVADKGGSIFTKTCFLLVLLVQDERRAME 972 HSP 3 Score: 112.464 bits (280), Expect = 4.242e-24 Identity = 78/281 (27.76%), Postives = 153/281 (54.45%), Query Frame = 1
Query: 3589 KKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEM----KLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYR---HSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKI----YCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFR---------KHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQR 4371
K+++I N+AA V+Q ++ Y +E V + K R RK K+M + +Q+ RM + K++Y + + + + +G+ R K+ + + H+ +VIQ++FR ++ RK +K +A++IQ++ R ++RK Y +A+ V+Q RG+ VRK++ HH+SA +IQ +R + +++F+C + +AIV+Q+++R K Y+R++ ++ + IQS R+ + ++ QMK+AA + +G+ RK + T +
Sbjct: 544 KRRLIRQNKAAVVIQTLWRGY-------SAREKVKNLLKKNRSAAFRKWHAKKMLERNTAALRIQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFWKEYMRKKISQLHRFAKIIQSNYRRHLEQTRFLQMKRAALW-----RGHCSRKLHDTNK 812 HSP 4 Score: 101.293 bits (251), Expect = 1.210e-20 Identity = 92/346 (26.59%), Postives = 172/346 (49.71%), Query Frame = 1
Query: 4573 EQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKL--KNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQK---NSCVTIQNYFKAYLIRKKYLEIRQKTIFIQ----CLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYI---------LRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATL 5556
E +A R+IQ +R + KLQK+I + KN T+ +Q+L + FI ++ + +++++Q ++RG++A +K L KN S +K + + L R+T A++ IQ + R LC+ R+YL ++R A +Q ++RG+ R+ F K ++ V IQ+ F+AYLIRK+ +++Q + IQ V+R + R+ +K +V+++Q RG+ + + ++ + IQ FRRF+ + F LK ++I++Q+ +R + +RK+ + + IQS RR++ ++F +K A L
Sbjct: 501 ETRAARVIQGAWRRY--------------KLQKDI-ALMHEKNLAATK-----IQALARKFILKRRLIRQNKAAVVIQTLWRGYSAREKVKNLLKKNRSAAFRK---WHAKKMLERNT--AALRIQAWYRMQLCK-----------------RQYLEMKR------KAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFWKEYMRKKISQLHRFAKIIQSNYRRHLEQTRFLQMKRAAL 798 HSP 5 Score: 97.4413 bits (241), Expect = 1.535e-19 Identity = 73/282 (25.89%), Postives = 145/282 (51.42%), Query Frame = 1
Query: 4489 SVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHF--ICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLK---NASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLL----AAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYL---------IRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVI 5280
++ K LAAT IQ +AR +++++R++ + KA +IQ +R ++ R + +KN + +K ++ +N R +Q+ + + ++ Y +++ ++ VQ FRG KF LK +AS+ IQ R Y K + +++IQ++ R + R Q++ A ++LQ FR + + + + ++A +IQ +R +T + HFLC K S + +Q ++A + +RKK ++ + IQ RR++ + RFL++K + +
Sbjct: 522 ALMHEKNLAATKIQALARKFILKRRLIRQNKAAVVIQTLWRGYSAREKVKNLLKKNRSAAFRKWHAKKMLERNTAALR-----IQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFWKEYMRKKISQLHRFAKIIQSNYRRHLEQTRFLQMKRAAL 798 HSP 6 Score: 84.3445 bits (207), Expect = 1.566e-15 Identity = 104/374 (27.81%), Postives = 178/374 (47.59%), Query Frame = 1
Query: 3901 VIQNSFRCFMYRK---MFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVR---KTLNSHHQSATLIQHFYRSYKIRKNFICKRN-AAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKK---AATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQL 4992
VIQ ++R + +K + +A IQ R FI ++ Q A VIQ RG+ R K L ++SA +R + +K + +RN AA+ IQ +R ++QY E ++K + +Q+ R + K++ +KK A+ IQ + Y+IRK+ +++AV+IQ+ R + RK+ Q R F ++S A ++Q RG+ VRK + ++ +IQ +R T + HF+C K +AI LQ+ R + F K ++ +K Q R + II Q +R +FL++K A++ R +C KL+ DT N I +++ +R R+K + +L
Sbjct: 507 VIQGAWRRYKLQKDIALMHEKNLAATKIQALARKFILKRRLIRQNKAAVVIQTLWRGYSAREKVKNLLKKNRSAA-----FRKWHAKK--MLERNTAALRIQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFRACVQRKAEQK------------RYFEIKS-------AVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKF-------------WKEYMRKKISQLHRFAKII-QSNYRRHLEQTRFLQMKRAALW-----RGHCSRKLH-DT-NKVISMRQRLREVNQRVKEEDKL 833 HSP 7 Score: 82.8037 bits (203), Expect = 4.621e-15 Identity = 85/322 (26.40%), Postives = 156/322 (48.45%), Query Frame = 1
Query: 4222 NETRKKVIFIQSLIRQF-----IAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXX---XYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQK---NAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQK----LRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCV 5142
NETR + IQ R++ IA+ K + AAT IQ +A+ +I++++ + Q ++AV+IQ R Y +R+ + + ++ L R+ ++ A +Q R YL KR KAV +Q ++R H RS F K +A++ +Q R YLIRK ++ + +L+Q + + RK QK ++S+ +++Q FRG+ K + +++ IQ RR+ + + + ++IV+Q+ R + K+ ++ + I Q H + A+IIQ+ YR + + FL K + +
Sbjct: 500 NETRAARV-IQGAWRRYKLQKDIALMHEKNL--AATKIQALARKFILKRRLIRQNKAAVVIQTLWRGYSAREKVKNLLKKNRSAAFRKWHAKKMLERNTAALRIQAWYRMQLCKRQYLEMKR-----KAV-CVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFWKEYMRKKISQLH--------------RFAKIIQSNYRRHLEQTRFLQMKRAAL 798 HSP 8 Score: 76.2554 bits (186), Expect = 5.299e-13 Identity = 70/271 (25.83%), Postives = 128/271 (47.23%), Query Frame = 1
Query: 2440 KSTKIIQKYVKGYLARKKFVKLTK---AIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQF--LKMRN-SVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQ----YLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQK 3222
++ ++IQ + Y +K + + A IQ+ R + +R Q KAAV+IQ+ +R R NL K + + +K+ +R + + IQ + R + +R +L+ K ++ +F G+L+R +F LK R+ + +++Q R Y +KE K +LIQ RA +QR+ Q +++A +++Q FR + VRK + SA+VIQ R Q+++L +K+S +V+Q+
Sbjct: 503 RAARVIQGAWRRYKLQKDIALMHEKNLAATKIQALARKFILKRRLIRQNKAAVVIQTLWRGYSAREKVKNLLKKN---RSAAFRKWHAKKMLERNTAALRIQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRA-----------------------YLIRKELSKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQ 747 HSP 9 Score: 61.6178 bits (148), Expect = 1.261e-8 Identity = 63/273 (23.08%), Postives = 127/273 (46.52%), Query Frame = 1
Query: 2731 IQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFL---IQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKN 3540
IQ R FI +R ++ A +++ + GY R+ K++N LL+KN R + R ++ AKK + + +A + IQ R + +R++ ++ A+ +Q FR + R KF ++++++VIQ R+ + +K K+KQ+ ++IQ+ + + V++ QK+Y +++ + +++Q FR RK + +V+Q + ++ FL LK I +Q+ RA + ++ K
Sbjct: 534 IQALARKFILKRRLIRQNKAAVVIQTLWRGYSARE---KVKN---LLKKN-RSAAFR------------------KWHAKK-MLERNTAALRIQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVLIQRWFR-------------------ACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFWKE 761
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Zebrafish
Match: myo5b (myosin VB [Source:ZFIN;Acc:ZDB-GENE-031219-7]) HSP 1 Score: 74.3294 bits (181), Expect = 1.474e-13 Identity = 51/145 (35.17%), Postives = 78/145 (53.79%), Query Frame = 1
Query: 2386 IQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK--KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLN--LRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEH 2808
IQ +RG+L R Y++IRKS +Q+Y +GYLAR+ + ++LT+A V+ Q +R RR Y +A + IQ+F R RR Y L +IIQK V L ++K ++ + I+IQ + R +R + K EH
Sbjct: 119 IQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEARSAEH 263 HSP 2 Score: 71.2478 bits (173), Expect = 1.532e-12 Identity = 46/130 (35.38%), Postives = 79/130 (60.77%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLR--SSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRD--TRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRK 5028
A IK+QK +RG+L R + + R I +Q +G++AR+ + LR +++I QK +R +++L+++ A I IQ R +LY++ + +++IQK VRG+L R KYQR AAI++Q +R+
Sbjct: 115 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRR 244 HSP 3 Score: 69.707 bits (169), Expect = 4.384e-12 Identity = 48/141 (34.04%), Postives = 76/141 (53.90%), Query Frame = 1
Query: 2200 YLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQK--NYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVK--LTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYR 2610
YL + R K + + I IQK R +L RIRY KI+ + + LQ + R YL ++ L++ R+ +I Q R R Y R+R++ IQ + +G R+ + + L ++IQ RG+ R+ Y AA++IQ FYR
Sbjct: 103 YLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 243 HSP 4 Score: 65.0846 bits (157), Expect = 1.840e-10 Identity = 42/135 (31.11%), Postives = 78/135 (57.78%), Query Frame = 1
Query: 5482 CVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL---VVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQ--LMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKR 5871
C+KIQ +R ++ +++ I+ + + +Q++ RG R +Y ++++L V QK R VR +L +++++I IQ+F R + + YQ L+ +IQK R ++ RK++ + I+IQ F+RR AKR
Sbjct: 116 CIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLAR-RYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKR 249 HSP 5 Score: 64.6994 bits (156), Expect = 2.639e-10 Identity = 48/148 (32.43%), Postives = 76/148 (51.35%), Query Frame = 1
Query: 2719 SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK--QFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQ--YLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQ 3150
+CI IQK +RG++ R + K + + L+ Y GYL R+ + L++ + ++ QK RM+ +R +E++ + A I IQ R + RR +Q L + A+IIQKT R + VRKK+ Y+AIVIQ
Sbjct: 115 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVR-----------------------REYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQ 239 HSP 6 Score: 64.3142 bits (155), Expect = 3.613e-10 Identity = 56/164 (34.15%), Postives = 82/164 (50.00%), Query Frame = 1
Query: 4921 RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQ--KAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLK 5406
R A I IQK VRG+L RI+Y++ +AI LQR+ R YL R ++ + +AA I Q YR +R +L + + +TIQ + + IR+ Y E FL L +IIQK RG+ +KY + + A I IQ +RR + + LK
Sbjct: 113 RFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQE--------------------FL-LHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLK 255 HSP 7 Score: 62.7734 bits (151), Expect = 1.166e-9 Identity = 53/150 (35.33%), Postives = 77/150 (51.33%), Query Frame = 1
Query: 4846 KLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQL---LAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIR---AHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSV 5277
K + A I IQK VR + Q YR R ++I +Q+Y RG+L R +Y L AA+I Q+ +R + R ++A IQ F RG IR FL + + IQ + +L+RKKY R I IQC RR ++ + +LK+
Sbjct: 111 KFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLAR-RYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMI-IQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEA 258 HSP 8 Score: 59.6918 bits (143), Expect = 9.585e-9 Identity = 39/127 (30.71%), Postives = 69/127 (54.33%), Query Frame = 1
Query: 3760 ILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARK--KYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIK--VIQKNIRGFLVRKTLNSHHQSATLIQHFYR 4128
I +Q +R + + RY+K + +T+ ++ +GY AR+ + L + ++ Q +R R+ +L ++ + I IQ + RG R++Y K +IQK +RG+LVRK +A +IQ FYR
Sbjct: 117 IKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 243 HSP 9 Score: 59.6918 bits (143), Expect = 9.853e-9 Identity = 43/160 (26.88%), Postives = 86/160 (53.75%), Query Frame = 1
Query: 3130 YSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIK---MHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQI 3600
++ I IQK VR + + Y KI++S + +Q++ +G+ L R+Y + L++ ++ +I QK +R + R+++L R+ I +Q + + + + Q+FL L + + IQK +R L R++Y +++ A I IQ +R + K+Q+
Sbjct: 114 FACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGY------------------LARRY---AEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFL-LHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQL 251 HSP 10 Score: 58.5362 bits (140), Expect = 2.803e-8 Identity = 47/142 (33.10%), Postives = 76/142 (53.52%), Query Frame = 1
Query: 4681 GYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHK--KFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLL--AAIILQRHFRKYLIIRRIDLEQKAARIIQNFYR 5094
YL + + R I +Q ++G++ R Y+K+R S+I +Q+ RG+ A + + L+L A++ QK R + Y R A I IQ + RG R YQ LL A+I+Q+ R +L+ ++ + AA +IQ FYR
Sbjct: 102 AYLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 243 HSP 11 Score: 58.5362 bits (140), Expect = 2.907e-8 Identity = 42/137 (30.66%), Postives = 84/137 (61.31%), Query Frame = 1
Query: 2995 ATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRK--KFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXX--XXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQF 3393
A I IQ VR +QR +++ +R +AI +Q+ R Y R+ + L +A++ QK R + ++ YL+++++V+ IQ T+G +++ Y++ + + +I Q VR +L++K+Y + R + I+IQ +R + A++Q
Sbjct: 115 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQL 251 HSP 12 Score: 55.4546 bits (132), Expect = 2.560e-7 Identity = 34/77 (44.16%), Postives = 47/77 (61.04%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKI--FLKLKNASIIISKHVRGVLVRNHF 6153
L KL+ K R A I IQKTV+G+ R Y+ ++KS I LQR+ RG+L R+ L+L A++I K R V VR +
Sbjct: 104 LEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREY 180 HSP 13 Score: 53.9138 bits (128), Expect = 8.594e-7 Identity = 36/116 (31.03%), Postives = 63/116 (54.31%), Query Frame = 1
Query: 5899 IFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIR----------------KHYKILQ---------KSVIQLQRFIRGFLIRKIFLK--LKNASIIISKHVRGVLVRNHFQKNK 6165
I +Q VRG L +++Y+K+R + I +Q+ +GY R K Y+++Q ++VI +Q F RG IR+++ + L + ++II K VRG LVR +Q+++
Sbjct: 117 IKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSR 232 HSP 14 Score: 53.1434 bits (126), Expect = 1.714e-6 Identity = 46/167 (27.54%), Postives = 81/167 (48.50%), Query Frame = 1
Query: 5236 YISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKN-----FRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKII--KLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYR 5715
Y+ + R + + + I IQK RG+ +Y K +K+ I +Q+ RR++E+ L A++I QK +R +R+E Y+R ++ A + IQ RG+F+R Y++ + + IQK +R +VR ++ + + I IQ FYR
Sbjct: 103 YLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEM---LRLTRAAVICQKQYRMVQVRRE-------------YLR----------VRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 243 HSP 15 Score: 52.7582 bits (125), Expect = 2.191e-6 Identity = 44/154 (28.57%), Postives = 76/154 (49.35%), Query Frame = 1
Query: 3466 KLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRS--CKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFR 3921
K + I IQK +R LQR RY K +K+ I +QR R + +++ +AA + QK ++ ++++ +++ +V IQ + R + R+ +Q+ LL K + I K V+G+ RKKY R++ IVIQ +R
Sbjct: 111 KFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQE-----FLLHHK----------------AMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 243 HSP 16 Score: 51.2174 bits (121), Expect = 7.050e-6 Identity = 46/146 (31.51%), Postives = 75/146 (51.37%), Query Frame = 1
Query: 3883 YRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQ---TTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRK---NFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMK 4302
+R + I IQ + R ++ R + I+ SAI +Q+Y RG++ R+ Y T A + QK R VR+ ++ IQ F R IR+ F+ + A++IQK R +R++Y +R I IQ R+ A ++ KQ+K
Sbjct: 112 FRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARR-YAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLH-HKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLK 255
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Zebrafish
Match: myo5b (myosin VB [Source:ZFIN;Acc:ZDB-GENE-031219-7]) HSP 1 Score: 78.1814 bits (191), Expect = 1.676e-13 Identity = 57/170 (33.53%), Postives = 90/170 (52.94%), Query Frame = 1
Query: 2386 IQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK--KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLN--LRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNL 2883
IQ +RG+L R Y++IRKS +Q+Y +GYLAR+ + ++LT+A V+ Q +R RR Y +A + IQ+F R RR Y L +IIQK V L ++K ++ + I+IQ + R +R + K EH+ +K + M N ++ LQK +
Sbjct: 768 IQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEARSAEHF------KKLNVGMENKIVQLQKKM 931 HSP 2 Score: 69.707 bits (169), Expect = 5.597e-11 Identity = 48/141 (34.04%), Postives = 76/141 (53.90%), Query Frame = 1
Query: 2200 YLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQK--NYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVK--LTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYR 2610
YL + R K + + I IQK R +L RIRY KI+ + + LQ + R YL ++ L++ R+ +I Q R R Y R+R++ IQ + +G R+ + + L ++IQ RG+ R+ Y AA++IQ FYR
Sbjct: 752 YLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 892 HSP 3 Score: 68.9366 bits (167), Expect = 1.017e-10 Identity = 46/130 (35.38%), Postives = 79/130 (60.77%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLR--SSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRD--TRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRK 5028
A IK+QK +RG+L R + + R I +Q +G++AR+ + LR +++I QK +R +++L+++ A I IQ R +LY++ + +++IQK VRG+L R KYQR AAI++Q +R+
Sbjct: 764 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRR 893 HSP 4 Score: 64.6994 bits (156), Expect = 1.897e-9 Identity = 55/152 (36.18%), Postives = 77/152 (50.66%), Query Frame = 1
Query: 4858 ASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQL---LAAIILQRHF------RKYLIIRRIDLEQKAARIIQNFYRGYTIR---AHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSV 5277
A I IQK VR + Q YR R ++I +Q+Y RG+L R +Y L AA+I Q+ + R+YL +RR A IQ F RG IR FL + + IQ + +L+RKKY R I IQC RR ++ + +LK+
Sbjct: 764 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLAR-RYAEMLRLTRAAVICQKQYRMVQVRREYLRVRR------AVITIQAFTRGMFIRRLYQEFLLHHKAMI-IQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEA 907 HSP 5 Score: 63.929 bits (154), Expect = 3.361e-9 Identity = 48/148 (32.43%), Postives = 76/148 (51.35%), Query Frame = 1
Query: 2719 SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK--QFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQ--YLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQ 3150
+CI IQK +RG++ R + K + + L+ Y GYL R+ + L++ + ++ QK RM+ +R +E++ + A I IQ R + RR +Q L + A+IIQKT R + VRKK+ Y+AIVIQ
Sbjct: 764 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVR-----------------------REYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQ 888 HSP 6 Score: 63.929 bits (154), Expect = 3.475e-9 Identity = 42/135 (31.11%), Postives = 78/135 (57.78%), Query Frame = 1
Query: 5482 CVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLV---VFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQ--LMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKR 5871
C+KIQ +R ++ +++ I+ + + +Q++ RG R +Y ++++L V QK R VR +L +++++I IQ+F R + + YQ L+ +IQK R ++ RK++ + I+IQ F+RR AKR
Sbjct: 765 CIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLAR-RYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKR 898 HSP 7 Score: 63.929 bits (154), Expect = 3.534e-9 Identity = 47/127 (37.01%), Postives = 74/127 (58.27%), Query Frame = 1
Query: 4921 RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQ--KAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLE--IRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQ 5289
R A I IQK VRG+L RI+Y++ +AI LQR+ R YL R ++ + +AA I Q YR +R +L + + +TIQ + + IR+ Y E + K + IQ VR ++ R ++ R + + I+IQ
Sbjct: 762 RFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQ 888 HSP 8 Score: 58.151 bits (139), Expect = 1.966e-7 Identity = 44/160 (27.50%), Postives = 85/160 (53.12%), Query Frame = 1
Query: 3130 YSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCR---QKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQI 3600
++ I IQK VR + + Y KI++S + +Q++ +G+ L R+Y + L++ ++ +I QK +R + R+++L R+ I +Q + + R Q+FL L + + IQK +R L R++Y +++ A I IQ +R + K+Q+
Sbjct: 763 FACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGY------------------LARRY---AEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFL-LHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQL 900 HSP 9 Score: 57.3806 bits (137), Expect = 2.823e-7 Identity = 39/127 (30.71%), Postives = 69/127 (54.33%), Query Frame = 1
Query: 3760 ILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARK--KYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIK--VIQKNIRGFLVRKTLNSHHQSATLIQHFYR 4128
I +Q +R + + RY+K + +T+ ++ +GY AR+ + L + ++ Q +R R+ +L ++ + I IQ + RG R++Y K +IQK +RG+LVRK +A +IQ FYR
Sbjct: 766 IKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 892 HSP 10 Score: 57.3806 bits (137), Expect = 3.070e-7 Identity = 55/155 (35.48%), Postives = 80/155 (51.61%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKI--FLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY--CLLKSYTLLIQQRWRFIVLKR-------SAVVIQRIWR 6360
L KL+ K R A I IQKTV+G+ R Y+ ++KS I LQR+ RG+L R+ L+L A++I K R V VR + LR R A I IQA+ R +R Y LL ++IQ+ R ++++ +A+VIQ +R
Sbjct: 753 LEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREY--------------LRVR-RAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 892 HSP 11 Score: 57.3806 bits (137), Expect = 3.483e-7 Identity = 44/127 (34.65%), Postives = 71/127 (55.91%), Query Frame = 1
Query: 4726 ILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNA--HKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLL--AAIILQRHFRKYLIIRRIDLEQKAARIIQNFYR 5094
I +Q ++G++ R Y+K+R S+I +Q+ RG+ A + + L+L A++ QK R + Y R A I IQ + RG R YQ LL A+I+Q+ R +L+ ++ + AA +IQ FYR
Sbjct: 766 IKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 892 HSP 12 Score: 56.225 bits (134), Expect = 6.380e-7 Identity = 42/137 (30.66%), Postives = 84/137 (61.31%), Query Frame = 1
Query: 2995 ATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRK--KFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXX--XXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQF 3393
A I IQ VR +QR +++ +R +AI +Q+ R Y R+ + L +A++ QK R + ++ YL+++++V+ IQ T+G +++ Y++ + + +I Q VR +L++K+Y + R + I+IQ +R + A++Q
Sbjct: 764 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQL 900 HSP 13 Score: 53.1434 bits (126), Expect = 5.628e-6 Identity = 36/116 (31.03%), Postives = 63/116 (54.31%), Query Frame = 1
Query: 5899 IFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIR----------------KHYKILQ---------KSVIQLQRFIRGFLIRKIFLK--LKNASIIISKHVRGVLVRNHFQKNK 6165
I +Q VRG L +++Y+K+R + I +Q+ +GY R K Y+++Q ++VI +Q F RG IR+++ + L + ++II K VRG LVR +Q+++
Sbjct: 766 IKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSR 881 HSP 14 Score: 52.373 bits (124), Expect = 9.885e-6 Identity = 47/182 (25.82%), Postives = 82/182 (45.05%), Query Frame = 1
Query: 3853 GYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQ--MKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQ 4392
Y + + +R + I IQ + R ++ R + I+ SAI +Q+Y RG++ R+ Y ++R T AA++ QKQ+R +R++Y R+ VI IQ+ R + Y++ + A IQK +G+++RKKY R +A++IQ
Sbjct: 751 AYLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARR-YAE---------------MLRLT----------------------------RAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQ 888
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Zebrafish
Match: myo5b (myosin VB [Source:ZFIN;Acc:ZDB-GENE-031219-7]) HSP 1 Score: 78.1814 bits (191), Expect = 1.685e-13 Identity = 57/170 (33.53%), Postives = 90/170 (52.94%), Query Frame = 1
Query: 2386 IQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK--KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLN--LRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNL 2883
IQ +RG+L R Y++IRKS +Q+Y +GYLAR+ + ++LT+A V+ Q +R RR Y +A + IQ+F R RR Y L +IIQK V L ++K ++ + I+IQ + R +R + K EH+ +K + M N ++ LQK +
Sbjct: 768 IQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEARSAEHF------KKLNVGMENKIVQLQKKM 931 HSP 2 Score: 69.707 bits (169), Expect = 5.443e-11 Identity = 48/141 (34.04%), Postives = 76/141 (53.90%), Query Frame = 1
Query: 2200 YLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQK--NYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVK--LTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYR 2610
YL + R K + + I IQK R +L RIRY KI+ + + LQ + R YL ++ L++ R+ +I Q R R Y R+R++ IQ + +G R+ + + L ++IQ RG+ R+ Y AA++IQ FYR
Sbjct: 752 YLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 892 HSP 3 Score: 68.9366 bits (167), Expect = 1.076e-10 Identity = 46/130 (35.38%), Postives = 79/130 (60.77%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLR--SSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRD--TRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRK 5028
A IK+QK +RG+L R + + R I +Q +G++AR+ + LR +++I QK +R +++L+++ A I IQ R +LY++ + +++IQK VRG+L R KYQR AAI++Q +R+
Sbjct: 764 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRR 893 HSP 4 Score: 64.6994 bits (156), Expect = 1.830e-9 Identity = 55/152 (36.18%), Postives = 77/152 (50.66%), Query Frame = 1
Query: 4858 ASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQL---LAAIILQRHF------RKYLIIRRIDLEQKAARIIQNFYRGYTIR---AHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSV 5277
A I IQK VR + Q YR R ++I +Q+Y RG+L R +Y L AA+I Q+ + R+YL +RR A IQ F RG IR FL + + IQ + +L+RKKY R I IQC RR ++ + +LK+
Sbjct: 764 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLAR-RYAEMLRLTRAAVICQKQYRMVQVRREYLRVRR------AVITIQAFTRGMFIRRLYQEFLLHHKAMI-IQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEA 907 HSP 5 Score: 63.929 bits (154), Expect = 3.496e-9 Identity = 48/148 (32.43%), Postives = 76/148 (51.35%), Query Frame = 1
Query: 2719 SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK--QFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQ--YLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQ 3150
+CI IQK +RG++ R + K + + L+ Y GYL R+ + L++ + ++ QK RM+ +R +E++ + A I IQ R + RR +Q L + A+IIQKT R + VRKK+ Y+AIVIQ
Sbjct: 764 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVR-----------------------REYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQ 888 HSP 6 Score: 63.929 bits (154), Expect = 3.586e-9 Identity = 47/127 (37.01%), Postives = 74/127 (58.27%), Query Frame = 1
Query: 4921 RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQ--KAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLE--IRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQ 5289
R A I IQK VRG+L RI+Y++ +AI LQR+ R YL R ++ + +AA I Q YR +R +L + + +TIQ + + IR+ Y E + K + IQ VR ++ R ++ R + + I+IQ
Sbjct: 762 RFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQ 888 HSP 7 Score: 63.5438 bits (153), Expect = 3.771e-9 Identity = 42/135 (31.11%), Postives = 78/135 (57.78%), Query Frame = 1
Query: 5482 CVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL---VVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQ--LMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKR 5871
C+KIQ +R ++ +++ I+ + + +Q++ RG R +Y ++++L V QK R VR +L +++++I IQ+F R + + YQ L+ +IQK R ++ RK++ + I+IQ F+RR AKR
Sbjct: 765 CIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLAR-RYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKR 898 HSP 8 Score: 57.7658 bits (138), Expect = 2.245e-7 Identity = 44/160 (27.50%), Postives = 85/160 (53.12%), Query Frame = 1
Query: 3130 YSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCR---QKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQI 3600
++ I IQK VR + + Y KI++S + +Q++ +G+ L R+Y + L++ ++ +I QK +R + R+++L R+ I +Q + + R Q+FL L + + IQK +R L R++Y +++ A I IQ +R + K+Q+
Sbjct: 763 FACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGY------------------LARRY---AEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFL-LHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQL 900 HSP 9 Score: 57.3806 bits (137), Expect = 2.913e-7 Identity = 55/155 (35.48%), Postives = 80/155 (51.61%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKI--FLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY--CLLKSYTLLIQQRWRFIVLKR-------SAVVIQRIWR 6360
L KL+ K R A I IQKTV+G+ R Y+ ++KS I LQR+ RG+L R+ L+L A++I K R V VR + LR R A I IQA+ R +R Y LL ++IQ+ R ++++ +A+VIQ +R
Sbjct: 753 LEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREY--------------LRVR-RAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 892 HSP 10 Score: 57.3806 bits (137), Expect = 2.987e-7 Identity = 39/127 (30.71%), Postives = 69/127 (54.33%), Query Frame = 1
Query: 3760 ILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARK--KYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIK--VIQKNIRGFLVRKTLNSHHQSATLIQHFYR 4128
I +Q +R + + RY+K + +T+ ++ +GY AR+ + L + ++ Q +R R+ +L ++ + I IQ + RG R++Y K +IQK +RG+LVRK +A +IQ FYR
Sbjct: 766 IKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 892 HSP 11 Score: 57.3806 bits (137), Expect = 3.305e-7 Identity = 44/127 (34.65%), Postives = 71/127 (55.91%), Query Frame = 1
Query: 4726 ILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNA--HKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLL--AAIILQRHFRKYLIIRRIDLEQKAARIIQNFYR 5094
I +Q ++G++ R Y+K+R S+I +Q+ RG+ A + + L+L A++ QK R + Y R A I IQ + RG R YQ LL A+I+Q+ R +L+ ++ + AA +IQ FYR
Sbjct: 766 IKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYR 892 HSP 12 Score: 56.225 bits (134), Expect = 6.753e-7 Identity = 42/137 (30.66%), Postives = 84/137 (61.31%), Query Frame = 1
Query: 2995 ATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRK--KFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXX--XXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQF 3393
A I IQ VR +QR +++ +R +AI +Q+ R Y R+ + L +A++ QK R + ++ YL+++++V+ IQ T+G +++ Y++ + + +I Q VR +L++K+Y + R + I+IQ +R + A++Q
Sbjct: 764 ACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQL 900 HSP 13 Score: 53.1434 bits (126), Expect = 5.713e-6 Identity = 36/116 (31.03%), Postives = 63/116 (54.31%), Query Frame = 1
Query: 5899 IFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIR----------------KHYKILQ---------KSVIQLQRFIRGFLIRKIFLK--LKNASIIISKHVRGVLVRNHFQKNK 6165
I +Q VRG L +++Y+K+R + I +Q+ +GY R K Y+++Q ++VI +Q F RG IR+++ + L + ++II K VRG LVR +Q+++
Sbjct: 766 IKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSR 881 HSP 14 Score: 52.373 bits (124), Expect = 9.702e-6 Identity = 47/182 (25.82%), Postives = 82/182 (45.05%), Query Frame = 1
Query: 3853 GYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQ--MKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQ 4392
Y + + +R + I IQ + R ++ R + I+ SAI +Q+Y RG++ R+ Y ++R T AA++ QKQ+R +R++Y R+ VI IQ+ R + Y++ + A IQK +G+++RKKY R +A++IQ
Sbjct: 751 AYLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARR-YAE---------------MLRLT----------------------------RAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQ 888
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Xenopus
Match: lrp8 (LDL receptor related protein 8 [Source:Xenbase;Acc:XB-GENE-980035]) HSP 1 Score: 567.385 bits (1461), Expect = 2.884e-163 Identity = 556/2165 (25.68%), Postives = 992/2165 (45.82%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIF------------------------NTHL-----SKTKVEDINKNMPIYIEATKLLLSECKV--------AIEKINSEVTKDSLKFKDD-IFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILVNIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFE----------------NPIXXXXXXXX-----------XXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLTS----------------------ANLFDKEI--------LLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKS---------ATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYL----ARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRS-SVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGY----LRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQY----YSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIK----MHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKS---------------------------YICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIA----ATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRA----HTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF-----NAHKKFLKLKNASICIQKNVRRYCQMKLYRD---TRNASIVIQKYVRGFL---------------------------CRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLI----RKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFR----RFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIF----VRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-----------FIVLKRSAVVIQRIWRGRQLRCHL 6384
D+ W+ +QE F WLN I N H + TK E K + +L S C++ AI ++ E+ L + D +K + + +++YN WL + ++ F +SL SN++ FI ++LWN DIA ++R + + + +L++ L++ L +++ LD AK+ + D LF KD+ K+S ++L F+ FL GEG++ + L VSH+QT +DE+DF V+NL+ D+ GVRL + + + + KLR PA+ +K N+E+A++A D G + G I I HRE+TLALLW ++ +D ++ +L EI++ + NP S+ LL+ WV +VC Y+ V N + + DGR FC L+++Y P YL LN + TT T +FD+ + LL+NE+ NF + + + +GG P ++ N IP + ++ L+F +RL+DL RAA IQ VWR YR V + L +K K+ + + Q V ++L+R R+ K SA +IQK +RRYL + + +++K+ AT+++Q ++ Y ++ ++ + S + +Q +R + +S+YK+I+++T +Q +++ +L R++++ + ++++IQ AF + KR+ +A +IIQ YR C+ N+ + I IQ V ++K I IQ + R +R FL K ++ L+ Y+ Y L RK+FL+MR++ I +Q + R + +R + + + ++ R KK++ K +L+Q+ VR Q+++F+ ++ AA +IQ +R + K+ + ++ ++A+VIQ R + +K L+++ +V + Q+L R Y +K++L++++++I IQ FR R ++ RK T VQ+ + M + R+ ++ ++ I +Q +R RR KA +Q ++R ++KKQ L +AA ++Q+++++ Y +K + + + IQ R RK + + + V+ +Q R + ++ QKK AT+T+ +G+ RK+ + + I IQ++FR + +K ++K +A+ IQ+ R + +R+ Y + K +Q RG VRK L H+SA LIQ FYR + + + R A+ +IQ +R H + Q Y +K +QS R + ++ KAAT IQ + +I+ K+Y T R + + IQ++ +L + L R+ Y R + ++Q R ++VRKRI+ Q++ ++Q YRA +R ++ A LQ RG +R+N ++QS + R Y++LR ++ +VQ +R N H +++ ++NA++CIQ R +K+ RD A+ +IQ++ + FL R +Y R A ++LQ FR + RI+ +A +IQ +R + + + +++ + IQ +KA + RK YL+ RQ + IQ R R + + IQ R + +Y+K + AV IQ+ FR R SE + +K A + IQ +R + +RK+ + + + +IQS + + ++ ++SA +IQ R I R ++ ++ K + IQ R +VR + + IQSFYRM+ + K Y + Q++ IQ+ R AR + YQ + +Q+ RG ++ Q+M A IQ+ K + RK Y L+ S I +QR R ++ R+ FLK ++A+I I RG+ R E L+ R A+ +IQ+ FR + Q Y K ++IQ+ +R ++ L +A+++Q ++RG++ R +L
Sbjct: 664 DERWMAKQERGFTWWLNFILTPDDFAVKRDSSKVQAATLILGSENAHKVSVPKAPTKEEVSLKAYTTRCKLNRLRRSACRLFTSEPVVKAILRLEVEIEAQRLLVRRDRHLWKDIGERQKILNWLLSYNPLWL----RIGLETIFGELISLESNSDVTGLAVFILNRLLWNPDIAAEYRHPSVPNLYRDGHEEALSKFTLKKLLLLIFFLDHAKQFRLIDHDPCLFWKDAEYKTSKDLLLAFSRDFLSGEGDLSRHLGYLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVTVELLAQSWSLSKKLRVPAISRLQKMHNVEVALQALTDRGVLLKDERGVSITSKDIVDRHRERTLALLWKIVFSFQVDVLLSTKQLKEEIQILKESYNTQKQLAALRSLANPAPTQTRESDQFEPEKYNERVSLLMEWVNAVCRFYSTKVQNFTVSFSDGRVFCYLVNHYHPSYLPLNAVCQRTTQTVECSQSGTAMLNSSDSDNSLEVWPGVFDQGVTSSALYKELLKNEQTNFSLVHAAVADLGGIPAMVHHSDMSNTIPDEKVVITFLSFLCARLLDLRKETRAARVIQTVWRNYRL--------------------KVEKKLLERKHKAAR----VIQRAVVQFLSRCRLQKRSHSAAVIQKYFRRYLAQRQLKELKALKHKELQDNATLIIQRFWKGYSARRRFIILRHSAICMQARVRAKIAQSSYKQIQQATVTLQSHMRAWLLGKKKRQEYLHIKSSVIIIQHAFTRW-KRQKQKRHTEAVLIIQKCYRRWKACKSMAQNM--AAIKIQSVYRMHRERQKFLDTKCKIIKIQSWFRCKKDREAFLMQKESILTLQKYYRAYKQGRLDRKKFLEMRSAAISIQAHYRGMRVRQLYYRIKAACVLQSYWRMRQ-EKKKYDHVKQLVVLLQSNVRKCQQQKQFKLMKRAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKAKLQVRSAVKI------------------------QALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQVHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCAR-------------------LQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVH-QYMAIRNAALCIQSAFR---GLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNF-------------------YQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLRER---------------EELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRYRSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNL 2715 HSP 2 Score: 376.711 bits (966), Expect = 4.507e-104 Identity = 446/1792 (24.89%), Postives = 788/1792 (43.97%), Query Frame = 1
Query: 2017 AASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMR---IIICQSVVKRY----LARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK----KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQK--------------------VVHKVLFKRKLEKRLRS-------CIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIIC----QKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISA---------------------------RKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRA----LLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLIC----RKQFQKEMKLVILLQSKIRMIITKKR----YQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQ----------KNI-----------------RGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFR----KHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLL----AAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEI----RQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRF----SELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGI-FVRLKYKKIIKL---VVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIAR----KRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGF----LIRKIFLKLKNASIIISKHVRGVLVRN--------------------------------HFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-FIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK---AGVLNFDVIGSEFIKLVKNLLYRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKS 6873
AA IQ V+R +R + F+ ++I +QS F C K ++ M+ I+ Q + Y L R + +M+ +AI IQ +YR R Y +IK+A VLQS++R +K Y + + ++++Q+N+R + +K ++++ +IQ Y + + A K +F ++ A VVIQSAFR R+ +Q+++AV IQ+ RS R+ +L ++++ I IQ V K K++++K + CI +Q +RG RR + A IL+ + + ++KQ+ + + I++Q++ R ++ + F+A K + + +Q R R+ + R AA+ IQ FR Y +RK +L S + IQ+ R QK YL+I+++ + +Q +G++ +K K I QS R+Y QKQ ++K+ + IQ+ +RA+ A RK K ++Q + +MH C+ ++ ++ IQ RA LQ+ Y++ KK+ +Q +R K ++Q+ ++AAT +Q F+S+I K++ ++ + IQ++ +C R ++ + K VI+LQS R + +KR Q I + G RK+YL + ++Q ++R R+ ++ +A VIQ R +R Y A +V+Q +N+ RG VR+ LN+ H +A LIQ Y+ + R+ F+ RNA I+ Q++FR IRQQY +K V+ +Q+ R + ++ M +AT IQ + + + Y T R +A++IQ+ + ++ KS R Y ++ +A IQ RG RK + + KA IQ +R H RS +I + A +Q+ R NK+ + L Y ++ + + +Q +RGF K + IQ + + + +Y++ ++A +IQ + R + + + L A I++Q R L+ R I AA IQ+FYR Y+ R +++ + TIQ ++A R Y R+ +Q R +R ++ + IQ+ + + + Y++ K + I IQ+ +R +E + F ++A+I IQ +R R+E K + + +IQS R + + K A ++IQ+H R +L++K+ +KL + +Q R R ++ + +Q++YRMH + + Y ++ ++ Q R AR K++ I+ + IQ FR A R +++ S I +Q+ + + +Y KM A ++IQ +G+ RK K ++ S +Q + R L R +L +++A+I I RG+L HF++ ++ + L+ R A+ KIQ R Y+Q+RR S + Q WR +I K R+ R R R + K E ++ NR + A D S ++ +L L LE T LS C+ + +S A K + L+ CNR + +EV+ + V NL K ++V S I L ++R K KG +IF TC L+ + Q++
Sbjct: 1436 AAIKIQSVYRMHRE----RQKFLDTKCKIIKIQSW---FRCKKDREAFLMQKESILTLQKYYRAYKQGRLDRKKFLEMRSAAISIQAHYRGMRVRQLYYRIKAA-CVLQSYWRMRQEKKKYDHVKQLVVLLQSNVRKCQQQKQFKLMKRAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKA-KLQVRSAVKIQALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQ-------------------VHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCARLQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVHQYMAIRNAALCIQSAFRGLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSE-------------------RKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRA-----------NKLRDSEKLQ--------YHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNFYQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLREREELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRYRSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNLRDMHNAATVVQAYYRMHRQRQYYFALQHAVRTTQVRFRANRARVDAVKKYATIRMAVKRIQSAFRARKAARDAEKD-SAAIVIQAQWKMHTVRREYVKMTEAAVVIQAVFRGHRTRKMLKAMEVSACLIQAWYRSCRLTRLQRAQYLSIRSAAITIQSAFRGMLAHRVAEREQAELITNAILLLLQMWYRAKLQRRYYLHFRQKIVTLQRAIRAWLQLRNNAACKIQRSMRDYLQRRRQARAVSGIVKFQALWRGYICRKARDTKAVRVLRKRLQRVSQDVK----EEDKLCNRTVVA------------------LDYLLSSKHLSFILAALQHLEVATRLSAVCCENMAQSGAVKTIFVLIRSCNRSIPCMEVIKLSVMVLLNLSKYERTVQAVYEVENSVDILLDLMQIFREKAGDKVSDKGGSIFTKTCCLMAIFALHSQRA 3138 HSP 3 Score: 327.791 bits (839), Expect = 3.737e-89 Identity = 354/1410 (25.11%), Postives = 653/1410 (46.31%), Query Frame = 1
Query: 2014 RAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFR-RYLVQKN---YLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQ---------------------------SAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRL----RSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRML---------------------------SLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRA--LIQRRKFQYLR--NAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXC----QSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKK----QIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMII----TKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYV----RRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFI----CQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFR----GFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQK-------AARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVR----RYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRR----YICISKFKMIKSATLIIQKHIRGIFV-RLKYKKIIKLV-----VFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRS 5874
RAA IQ +R +R F +++QS RR K ++ + I Q++ + Y AR R ++K+++I IQ +R R+RY ++ AT +Q FR + +QK Y+ + + + +Q +RG+ R + K+ I+Q + + +K++ L +A ++IQ +A+RGY R++ Q AA+ IQ+ +RS R+ YL +R+SV+ IQ+ RK +K+ R+ + +Q RG++ R+ + +A ++ F Y +KQ M+ + + +Q+ R + ++R + KSA +IQ ++ + + ++ A + A+ LIQ RA L Q ++F YLR +A ++Q +R + VR++ + +A IQ RS I K Y ++ + L IQ+H FL + + +R+ QS R ++++K+ L++++S I++Q+++RA+ RKQ+L + T ++Q + + R+ + IQ R + QR Y + ++A +Q ++R+ KE+ Q + AA +Q F+ ++ + +IQ++ + + R++F IL Q + RM + +++Y + A + + +G+ R++ +S VIQ +FR + + +++ +AIVIQ+ + + +RK Y Q + IQ RG RK L+ H++A+ IQ +R ++ R +I + A VIQ++FR + +R QY+ ++ V+ IQS R F + + + AT IQ K + R Y + + +IQ R + + + + + + R L+R K AAT IQ R Y RK ++ +AV IQ YRA R H+ + AA LQ RG R + +Q K F RK Y +L++S+I++Q+ +R G +KFLK ++A+ICIQ R + + + A+ IQ R + Y AA+++QRH+R+Y R LE K AA I+Q YRG R + N+ +Q Y++ + R+ Y ++ Q R R + ++ ++M+V IQ R R K A++ IQ ++ + + + + A+++IQ FR + RK K + IQ++ R + +++ I+SA + IQ RG+ R+ ++ +L+ + +Q RA + R +L+ ++ I+ +Q R + +N K IQ++ R ++ R+R S I+ Q +R ++ +++
Sbjct: 1576 RAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKAKLQVRSAVKI-QALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQVHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCARLQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVHQYMAIRNAALCIQSAFRGLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNFYQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLREREELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRY---RSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNLRDMHNAATVVQAYYRMHRQRQYYFALQHAVRTTQVRFRANRARVDAVKKYATIRMAVKRIQSAFRARKAARDAEKDSAAIV-IQAQWKMHTVRREYVKMTEAAVVIQAVFRGHRTRKMLKAMEVSACLIQAWYRSCRLTRLQRAQYLSIRSAAITIQSAFRGMLAHRVAEREQAELITNAILLLLQMWYRAKLQRRYYLHFRQKIVTLQRAIRAWLQLRNNAACK-----IQRSMRDYLQRRRQARAVSGIVKFQALWRGYICRKA 2975
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Xenopus
Match: lrp8 (LDL receptor related protein 8 [Source:Xenbase;Acc:XB-GENE-980035]) HSP 1 Score: 567.77 bits (1462), Expect = 2.954e-163 Identity = 556/2165 (25.68%), Postives = 992/2165 (45.82%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIF------------------------NTHL-----SKTKVEDINKNMPIYIEATKLLLSECKV--------AIEKINSEVTKDSLKFKDD-IFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILVNIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFE----------------NPIXXXXXXXX-----------XXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLTS----------------------ANLFDKEI--------LLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKS---------ATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYL----ARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRS-SVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGY----LRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQY----YSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIK----MHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKS---------------------------YICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIA----ATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRA----HTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF-----NAHKKFLKLKNASICIQKNVRRYCQMKLYRD---TRNASIVIQKYVRGFL---------------------------CRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLI----RKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFR----RFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIF----VRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-----------FIVLKRSAVVIQRIWRGRQLRCHL 6384
D+ W+ +QE F WLN I N H + TK E K + +L S C++ AI ++ E+ L + D +K + + +++YN WL + ++ F +SL SN++ FI ++LWN DIA ++R + + + +L++ L++ L +++ LD AK+ + D LF KD+ K+S ++L F+ FL GEG++ + L VSH+QT +DE+DF V+NL+ D+ GVRL + + + + KLR PA+ +K N+E+A++A D G + G I I HRE+TLALLW ++ +D ++ +L EI++ + NP S+ LL+ WV +VC Y+ V N + + DGR FC L+++Y P YL LN + TT T +FD+ + LL+NE+ NF + + + +GG P ++ N IP + ++ L+F +RL+DL RAA IQ VWR YR V + L +K K+ + + Q V ++L+R R+ K SA +IQK +RRYL + + +++K+ AT+++Q ++ Y ++ ++ + S + +Q +R + +S+YK+I+++T +Q +++ +L R++++ + ++++IQ AF + KR+ +A +IIQ YR C+ N+ + I IQ V ++K I IQ + R +R FL K ++ L+ Y+ Y L RK+FL+MR++ I +Q + R + +R + + + ++ R KK++ K +L+Q+ VR Q+++F+ ++ AA +IQ +R + K+ + ++ ++A+VIQ R + +K L+++ +V + Q+L R Y +K++L++++++I IQ FR R ++ RK T VQ+ + M + R+ ++ ++ I +Q +R RR KA +Q ++R ++KKQ L +AA ++Q+++++ Y +K + + + IQ R RK + + + V+ +Q R + ++ QKK AT+T+ +G+ RK+ + + I IQ++FR + +K ++K +A+ IQ+ R + +R+ Y + K +Q RG VRK L H+SA LIQ FYR + + + R A+ +IQ +R H + Q Y +K +QS R + ++ KAAT IQ + +I+ K+Y T R + + IQ++ +L + L R+ Y R + ++Q R ++VRKRI+ Q++ ++Q YRA +R ++ A LQ RG +R+N ++QS + R Y++LR ++ +VQ +R N H +++ ++NA++CIQ R +K+ RD A+ +IQ++ + FL R +Y R A ++LQ FR + RI+ +A +IQ +R + + + +++ + IQ +KA + RK YL+ RQ + IQ R R + + IQ R + +Y+K + AV IQ+ FR R SE + +K A + IQ +R + +RK+ + + + +IQS + + ++ ++SA +IQ R I R ++ ++ K + IQ R +VR + + IQSFYRM+ + K Y + Q++ IQ+ R AR + YQ + +Q+ RG ++ Q+M A IQ+ K + RK Y L+ S I +QR R ++ R+ FLK ++A+I I RG+ R E L+ R A+ +IQ+ FR + Q Y K ++IQ+ +R ++ L +A+++Q ++RG++ R +L
Sbjct: 624 DERWMAKQERGFTWWLNFILTPDDFAVKRDSSKVQAATLILGSENAHKVSVPKAPTKEEVSLKAYTTRCKLNRLRRSACRLFTSEPVVKAILRLEVEIEAQRLLVRRDRHLWKDIGERQKILNWLLSYNPLWL----RIGLETIFGELISLESNSDVTGLAVFILNRLLWNPDIAAEYRHPSVPNLYRDGHEEALSKFTLKKLLLLIFFLDHAKQFRLIDHDPCLFWKDAEYKTSKDLLLAFSRDFLSGEGDLSRHLGYLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVTVELLAQSWSLSKKLRVPAISRLQKMHNVEVALQALTDRGVLLKDERGVSITSKDIVDRHRERTLALLWKIVFSFQVDVLLSTKQLKEEIQILKESYNTQKQLAALRSLANPAPTQTRESDQFEPEKYNERVSLLMEWVNAVCRFYSTKVQNFTVSFSDGRVFCYLVNHYHPSYLPLNAVCQRTTQTVECSQSGTAMLNSSDSDNSLEVWPGVFDQGVTSSALYKELLKNEQTNFSLVHAAVADLGGIPAMVHHSDMSNTIPDEKVVITFLSFLCARLLDLRKETRAARVIQTVWRNYRL--------------------KVEKKLLERKHKAAR----VIQRAVVQFLSRCRLQKRSHSAAVIQKYFRRYLAQRQLKELKALKHKELQDNATLIIQRFWKGYSARRRFIILRHSAICMQARVRAKIAQSSYKQIQQATVTLQSHMRAWLLGKKKRQEYLHIKSSVIIIQHAFTRW-KRQKQKRHTEAVLIIQKCYRRWKACKSMAQNM--AAIKIQSVYRMHRERQKFLDTKCKIIKIQSWFRCKKDREAFLMQKESILTLQKYYRAYKQGRLDRKKFLEMRSAAISIQAHYRGMRVRQLYYRIKAACVLQSYWRMRQ-EKKKYDHVKQLVVLLQSNVRKCQQQKQFKLMKRAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKAKLQVRSAVKI------------------------QALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQVHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCAR-------------------LQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVH-QYMAIRNAALCIQSAFR---GLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNF-------------------YQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLRER---------------EELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRYRSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNL 2675 HSP 2 Score: 375.555 bits (963), Expect = 1.162e-103 Identity = 476/1899 (25.07%), Postives = 826/1899 (43.50%), Query Frame = 1
Query: 2017 AASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMR---IIICQSVVKRY----LARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK----KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQK--------------------VVHKVLFKRKLEKRLRS-------CIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIIC----QKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISA---------------------------RKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRA----LLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLIC----RKQFQKEMKLVILLQSKIRMIITKKR----YQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQ----------KNI-----------------RGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFR----KHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLL-----AATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRS------HFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF----NAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFR-KYLIIRRIDLEQ---KAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYI----SRNRFLRLKMSVIIIQKVTRG-----------------------YFTHRKYVKQKKAVINIQKNFRRFS----ELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIR---------------------------RYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQ---KNCR-KFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSI---------------IIFVQSLVRGKLAKLKY-------------------------QKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIR----GFLIRKIFLKLKNASIIISKHVRGVLVRN---HFQKNKQHMKIFAQENLRKRLEASIKI-----------QAYFRCYIQKRRYCLLKSYTLLIQQRWR-FIVLKRSAVV-IQRIWRGRQLRCHLNAKKIGHEISEI-------RNRFIEANRRFSKFNTVRYIGKKALTDLKESE----LTVAKVLFCLTS------------LENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK---AGVLNFDVIGSEFIKLVKNLLYRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKS 6873
AA IQ V+R +R + F+ ++I +QS F C K ++ M+ I+ Q + Y L R + +M+ +AI IQ +YR R Y +IK+A VLQS++R +K Y + + ++++Q+N+R + +K ++++ +IQ Y + + A K +F ++ A VVIQSAFR R+ +Q+++AV IQ+ RS R+ +L ++++ I IQ V K K++++K + CI +Q +RG RR + A IL+ + + ++KQ+ + + I++Q++ R ++ + F+A K + + +Q R R+ + R AA+ IQ FR Y +RK +L S + IQ+ R QK YL+I+++ + +Q +G++ +K K I QS R+Y QKQ ++K+ + IQ+ +RA+ A RK K ++Q + +MH C+ ++ ++ IQ RA LQ+ Y++ KK+ +Q +R K ++Q+ ++AAT +Q F+S+I K++ ++ + IQ++ +C R ++ + K VI+LQS R + +KR Q I + G RK+YL + ++Q ++R R+ ++ +A VIQ R +R Y A +V+Q +N+ RG VR+ LN+ H +A LIQ Y+ + R+ F+ RNA I+ Q++FR IRQQY +K V+ +Q+ R + ++ M +AT IQ + + + Y T R +A++IQ+ + ++ KS + ++ R + +RK+L AA+ IQ R + R + + Q AV +IQ +RA+ +R H I K A + +Q RG+ +RK+ +QS K R YQ ++S+ ++Q +R +FL+L+ A+I IQ R + + +A+ IQ + R + R Y L A +Q+ +R K + Q KAA ++Q +RG R + TIQ FK++ RK YLE++ TI IQ R + R +FL+ + + I IQ RG + H Y+ K+A + IQ+++RR+ E K + L NA+II+Q +R RK + +Q+Y R R + K+ I+ A IQ R +K +V IQ + + VR ++ + ++ + IQ+ +R H K + M+ S +IQ ++CR + R ++L I+S I IQ FR LA R +R + + +++ RG + + K+ QK++ A I+IQ +G+ IRKH+ L+++V+ LQ R G R + + +NA I + RG LVR H ++ F ++ +L I Q ++R +Q+R Y + + +Q+ R ++ L+ +A IQR +R +L ++ +S I R R +R ++ D+KE + TV + + L+S LE T LS C+ + +S A K + L+ CNR + +EV+ + V NL K ++V S I L ++R K KG +IF TC L+ + Q++
Sbjct: 1396 AAIKIQSVYRMHRE----RQKFLDTKCKIIKIQSW---FRCKKDREAFLMQKESILTLQKYYRAYKQGRLDRKKFLEMRSAAISIQAHYRGMRVRQLYYRIKAA-CVLQSYWRMRQEKKKYDHVKQLVVLLQSNVRKCQQQKQFKLMKRAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKA-KLQVRSAVKIQALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQ-------------------VHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCARLQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVHQYMAIRNAALCIQSAFRGLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQ-ATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVI--KRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNFYQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLREREELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRYRSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNLRDMHNAATVVQAYYRMHRQRQYYFALQHAVRTTQVRFRANRARVDAVKKYATIRMAVKRIQSAFRARKAARDAEKDSAAIV-IQAQWKMHTVRREYVKMTEAAVVIQAVFRGHRTRKMLKAMEVSACLIQAWYRSCRLTRLQRAQYLSIRSAAITIQSAFRGMLAHRVAEREQAASKVRSFLVMTPYRKRFLRLRAQWRGYIQRRKFVQYKSAALLIQQRYRAYRLQKSQHRQKLQKAAIVIQAAYRGFKIRKHFVRLKQAVVTLQMHFRAVKTGRYERIRYTQSRNAVIKLQACARGWLVRKEVMHIKQFFLVFFYFYYLYIKHQLLGIYPIELITNAILLLLQMWYRAKLQRRYYLHFRQKIVTLQRAIRAWLQLRNNAACKIQR-----SMRDYLQRRRQARAVSGIVKFQALWRGYICRKARDTKAVRVLRKRLQRVSQDVKEEDKLCNRTVVALDYLLSSKHLSFILAALQHLEVATRLSAVCCENMAQSGAVKTIFVLIRSCNRSIPCMEVIKLSVMVLLNLSKYERTVQAVYEVENSVDILLDLMQIFREKAGDKVSDKGGSIFTKTCCLMAIFALHSQRA 3257
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Xenopus
Match: lrp8 (LDL receptor related protein 8 [Source:Xenbase;Acc:XB-GENE-980035]) HSP 1 Score: 566.229 bits (1458), Expect = 7.564e-163 Identity = 556/2165 (25.68%), Postives = 992/2165 (45.82%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIF------------------------NTHL-----SKTKVEDINKNMPIYIEATKLLLSECKV--------AIEKINSEVTKDSLKFKDD-IFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILVNIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFE----------------NPIXXXXXXXX-----------XXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLTS----------------------ANLFDKEI--------LLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKS---------ATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYL----ARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRS-SVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGY----LRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQY----YSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIK----MHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKS---------------------------YICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIA----ATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRA----HTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF-----NAHKKFLKLKNASICIQKNVRRYCQMKLYRD---TRNASIVIQKYVRGFL---------------------------CRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLI----RKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFR----RFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIF----VRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-----------FIVLKRSAVVIQRIWRGRQLRCHL 6384
D+ W+ +QE F WLN I N H + TK E K + +L S C++ AI ++ E+ L + D +K + + +++YN WL + ++ F +SL SN++ FI ++LWN DIA ++R + + + +L++ L++ L +++ LD AK+ + D LF KD+ K+S ++L F+ FL GEG++ + L VSH+QT +DE+DF V+NL+ D+ GVRL + + + + KLR PA+ +K N+E+A++A D G + G I I HRE+TLALLW ++ +D ++ +L EI++ + NP S+ LL+ WV +VC Y+ V N + + DGR FC L+++Y P YL LN + TT T +FD+ + LL+NE+ NF + + + +GG P ++ N IP + ++ L+F +RL+DL RAA IQ VWR YR V + L +K K+ + + Q V ++L+R R+ K SA +IQK +RRYL + + +++K+ AT+++Q ++ Y ++ ++ + S + +Q +R + +S+YK+I+++T +Q +++ +L R++++ + ++++IQ AF + KR+ +A +IIQ YR C+ N+ + I IQ V ++K I IQ + R +R FL K ++ L+ Y+ Y L RK+FL+MR++ I +Q + R + +R + + + ++ R KK++ K +L+Q+ VR Q+++F+ ++ AA +IQ +R + K+ + ++ ++A+VIQ R + +K L+++ +V + Q+L R Y +K++L++++++I IQ FR R ++ RK T VQ+ + M + R+ ++ ++ I +Q +R RR KA +Q ++R ++KKQ L +AA ++Q+++++ Y +K + + + IQ R RK + + + V+ +Q R + ++ QKK AT+T+ +G+ RK+ + + I IQ++FR + +K ++K +A+ IQ+ R + +R+ Y + K +Q RG VRK L H+SA LIQ FYR + + + R A+ +IQ +R H + Q Y +K +QS R + ++ KAAT IQ + +I+ K+Y T R + + IQ++ +L + L R+ Y R + ++Q R ++VRKRI+ Q++ ++Q YRA +R ++ A LQ RG +R+N ++QS + R Y++LR ++ +VQ +R N H +++ ++NA++CIQ R +K+ RD A+ +IQ++ + FL R +Y R A ++LQ FR + RI+ +A +IQ +R + + + +++ + IQ +KA + RK YL+ RQ + IQ R R + + IQ R + +Y+K + AV IQ+ FR R SE + +K A + IQ +R + +RK+ + + + +IQS + + ++ ++SA +IQ R I R ++ ++ K + IQ R +VR + + IQSFYRM+ + K Y + Q++ IQ+ R AR + YQ + +Q+ RG ++ Q+M A IQ+ K + RK Y L+ S I +QR R ++ R+ FLK ++A+I I RG+ R E L+ R A+ +IQ+ FR + Q Y K ++IQ+ +R ++ L +A+++Q ++RG++ R +L
Sbjct: 624 DERWMAKQERGFTWWLNFILTPDDFAVKRDSSKVQAATLILGSENAHKVSVPKAPTKEEVSLKAYTTRCKLNRLRRSACRLFTSEPVVKAILRLEVEIEAQRLLVRRDRHLWKDIGERQKILNWLLSYNPLWL----RIGLETIFGELISLESNSDVTGLAVFILNRLLWNPDIAAEYRHPSVPNLYRDGHEEALSKFTLKKLLLLIFFLDHAKQFRLIDHDPCLFWKDAEYKTSKDLLLAFSRDFLSGEGDLSRHLGYLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVTVELLAQSWSLSKKLRVPAISRLQKMHNVEVALQALTDRGVLLKDERGVSITSKDIVDRHRERTLALLWKIVFSFQVDVLLSTKQLKEEIQILKESYNTQKQLAALRSLANPAPTQTRESDQFEPEKYNERVSLLMEWVNAVCRFYSTKVQNFTVSFSDGRVFCYLVNHYHPSYLPLNAVCQRTTQTVECSQSGTAMLNSSDSDNSLEVWPGVFDQGVTSSALYKELLKNEQTNFSLVHAAVADLGGIPAMVHHSDMSNTIPDEKVVITFLSFLCARLLDLRKETRAARVIQTVWRNYRL--------------------KVEKKLLERKHKAAR----VIQRAVVQFLSRCRLQKRSHSAAVIQKYFRRYLAQRQLKELKALKHKELQDNATLIIQRFWKGYSARRRFIILRHSAICMQARVRAKIAQSSYKQIQQATVTLQSHMRAWLLGKKKRQEYLHIKSSVIIIQHAFTRW-KRQKQKRHTEAVLIIQKCYRRWKACKSMAQNM--AAIKIQSVYRMHRERQKFLDTKCKIIKIQSWFRCKKDREAFLMQKESILTLQKYYRAYKQGRLDRKKFLEMRSAAISIQAHYRGMRVRQLYYRIKAACVLQSYWRMRQ-EKKKYDHVKQLVVLLQSNVRKCQQQKQFKLMKRAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKAKLQVRSAVKI------------------------QALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQVHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCAR-------------------LQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVH-QYMAIRNAALCIQSAFR---GLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNF-------------------YQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLRER---------------EELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRYRSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNL 2675 HSP 2 Score: 372.859 bits (956), Expect = 7.317e-103 Identity = 439/1774 (24.75%), Postives = 785/1774 (44.25%), Query Frame = 1
Query: 2014 RAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFR-RYLVQKN---YLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQ---------------------------SAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRL----RSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRML---------------------------SLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRA--LIQRRKFQYLR--NAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXC----QSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKK----QIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMII----TKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYV----RRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFIC----QKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFR----GFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQK-------AARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVR----RYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRR----YICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQS--ITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRK---HYK--------------------------ILQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVL-VRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-FIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK---AGVLNFDVIGSEFIKLVKNLLYRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKS 6873
RAA IQ +R +R F +++QS RR K ++ + I Q++ + Y AR R ++K+++I IQ +R R+RY ++ AT +Q FR + +QK Y+ + + + +Q +RG+ R + K+ I+Q + + +K++ L +A ++IQ +A+RGY R++ Q AA+ IQ+ +RS R+ YL +R+SV+ IQ+ RK +K+ R+ + +Q RG++ R+ + +A ++ F Y +KQ M+ + + +Q+ R + ++R + KSA +IQ ++ + + ++ A + A+ LIQ RA L Q ++F YLR +A ++Q +R + VR++ + +A IQ RS I K Y ++ + L IQ+H FL + + +R+ QS R ++++K+ L++++S I++Q+++RA+ RKQ+L + T ++Q + + R+ + IQ R + QR Y + ++A +Q ++R+ KE+ Q + AA +Q F+ ++ + +IQ++ + + R++F IL Q + RM + +++Y + A + + +G+ R++ +S VIQ +FR + + +++ +AIVIQ+ + + +RK Y Q + IQ RG RK L+ H++A+ IQ +R ++ R +I + A VIQ++FR + +R QY+ ++ V+ IQS R F + + + AT IQ K + R Y + + +IQ R + + + + + + R L+R K AAT IQ R Y RK ++ +AV IQ YRA R H+ + AA LQ RG R + +Q K F RK Y +L++S+I++Q+ +R G +KFLK ++A+ICIQ R + + + A+ IQ R + Y AA+++QRH+R+Y R LE K AA I+Q YRG R + N+ +Q Y++ + R+ Y ++ Q R R + ++ ++M+V IQ R R K A++ IQ ++ + + + + A+++IQ FR + RK K + IQ++ R + +++ I+SA + IQ RG+ + + + ++ + R RFL ++ + I +QS YRM + Y++ +++ VIQ R F RK F+ +K ++ +Q FR ++ G+ +++Y + R A I +Q +G+ +RK H K I ++ LQ + R L R+ +L + + + + +R L +RN+ A+ KIQ R Y+Q+RR S + Q WR +I K R+ R R R + K E ++ NR + A D S ++ +L L LE T LS C+ + +S A K + L+ CNR + +EV+ + V NL K ++V S I L ++R K KG +IF TC L+ + Q++
Sbjct: 1536 RAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKAKLQVRSAVKI-QALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQVHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCARLQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVHQYMAIRNAALCIQSAFRGLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNFYQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLREREELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRY---RSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNLRDMHNAATVVQAYYRMHRQRQYYFALQHAVRTTQVRFRANRARVDAVKKYATIRMAVKRIQSAFRARKAARDAEKDSAAIV-IQAQWKMHTVRREYVKMTEAAVVIQAVFRGHRTRKMLKAMEVSACLIQAWYRSCRLTRLQRAQYLSIRSAAITIQSAFRGMLAH-RVAEREQAASKVRSFLVMTPYRKRFLRLRAAAIVLQSHYRMQRIKRAYEMQRETKAAIVIQAAYRGFKIRKHFVRLKQAVVTLQMHFR-------------------AVKTGRYERIRYTQSRNAVIKLQACARGWLVRKEVMHIKQFFLVFFYFYYLYIKHQLLGIYPIELITNAILLLLQMWYRAKLQRRYYLHFRQKIVTLQRAIRAWLQLRNN---------------------AACKIQRSMRDYLQRRRQARAVSGIVKFQALWRGYICRKARDTKAVRVLRKRLQRVSQDVK----EEDKLCNRTVVA------------------LDYLLSSKHLSFILAALQHLEVATRLSAVCCENMAQSGAVKTIFVLIRSCNRSIPCMEVIKLSVMVLLNLSKYERTVQAVYEVENSVDILLDLMQIFREKAGDKVSDKGGSIFTKTCCLMAIFALHSQRA 3241
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Xenopus
Match: lrp8 (LDL receptor related protein 8 [Source:Xenbase;Acc:XB-GENE-980035]) HSP 1 Score: 565.074 bits (1455), Expect = 1.774e-162 Identity = 556/2165 (25.68%), Postives = 990/2165 (45.73%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIF------------------------NTHL-----SKTKVEDINKNMPIYIEATKLLLSECKV--------AIEKINSEVTKDSLKFKDD-IFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILVNIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFE----------------NPIXXXXXXXX-----------XXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLTS----------------------ANLFDKEI--------LLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKS---------ATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYL----ARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRS-SVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGY----LRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQY----YSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIK----MHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKS---------------------------YICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIA----ATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRA----HTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF-----NAHKKFLKLKNASICIQKNVRRYCQMKLYRD---TRNASIVIQKYVRGFL---------------------------CRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLI----RKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFR----RFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIF----VRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-----------FIVLKRSAVVIQRIWRGRQLRCHL 6384
D+ W+ +QE F WLN I N H + TK E K + +L S C++ AI ++ E+ L + D +K + + +++YN WL + ++ F +SL SN++ FI ++LWN DIA ++R + + + +L++ L++ L +++ LD AK+ + D LF KD+ K+S ++L F+ FL GEG++ + L VSH+QT +DE+DF V+NL+ D+ GVRL + + + + KLR PA+ +K N+E+A++A D G + G I I HRE+TLALLW ++ +D ++ +L EI++ + NP S+ LL+ WV +VC Y+ V N + + DGR FC L+++Y P YL LN + TT T +FD+ + LL+NE+ NF + + + +GG P ++ N IP + ++ L+F +RL+DL RAA IQ VWR Y R KK K +I ++VV+ +L+R R+ K SA +IQK +RRYL + + +++K+ AT+++Q ++ Y ++ ++ + S + +Q +R + +S+YK+I+++T +Q +++ +L R++++ + ++++IQ AF + KR+ +A +IIQ YR C+ N+ + I IQ V ++K I IQ + R +R FL K ++ L+ Y+ Y L RK+FL+MR++ I +Q + R + +R + + + ++ R KK++ K +L+Q+ VR Q+++F+ ++ AA +IQ +R + K+ + ++ ++A+VIQ R + +K L+++ +V + Q+L R Y +K++L++++++I IQ FR R ++ RK T VQ+ + M + R+ ++ ++ I +Q +R RR KA +Q ++R ++KKQ L +AA ++Q+++++ Y +K + + + IQ R RK + + + V+ +Q R + ++ QKK AT+T+ +G+ RK+ + + I IQ++FR + +K ++K +A+ IQ+ R + +R+ Y + K +Q RG VRK L H+SA LIQ FYR + + + R A+ +IQ +R H + Q Y +K +QS R + ++ KAAT IQ + +I+ K+Y T R + + IQ++ +L + L R+ Y R + ++Q R ++VRKRI+ Q++ ++Q YRA +R ++ A LQ RG +R+N ++QS + R Y++LR ++ +VQ +R N H +++ ++NA++CIQ R +K+ RD A+ +IQ++ + FL R +Y R A ++LQ FR + RI+ +A +IQ +R + + + +++ + IQ +KA + RK YL+ RQ + IQ R R + + IQ R + +Y+K + AV IQ+ FR R SE + +K A + IQ +R + +RK+ + + + +IQS + + ++ ++SA +IQ R I R ++ ++ K + IQ R +VR + + IQSFYRM+ + K Y + Q++ IQ+ R AR + YQ + +Q+ RG ++ Q+M A IQ+ K + RK Y L+ S I +QR R ++ R+ FLK ++A+I I RG+ R E L+ R A+ +IQ+ FR + Q Y K ++IQ+ +R ++ L +A+++Q ++RG++ R +L
Sbjct: 658 DERWMAKQERGFTWWLNFILTPDDFAVKRDSSKVQAATLILGSENAHKVSVPKAPTKEEVSLKAYTTRCKLNRLRRSACRLFTSEPVVKAILRLEVEIEAQRLLVRRDRHLWKDIGERQKILNWLLSYNPLWL----RIGLETIFGELISLESNSDVTGLAVFILNRLLWNPDIAAEYRHPSVPNLYRDGHEEALSKFTLKKLLLLIFFLDHAKQFRLIDHDPCLFWKDAEYKTSKDLLLAFSRDFLSGEGDLSRHLGYLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVTVELLAQSWSLSKKLRVPAISRLQKMHNVEVALQALTDRGVLLKDERGVSITSKDIVDRHRERTLALLWKIVFSFQVDVLLSTKQLKEEIQILKESYNTQKQLAALRSLANPAPTQTRESDQFEPEKYNERVSLLMEWVNAVCRFYSTKVQNFTVSFSDGRVFCYLVNHYHPSYLPLNAVCQRTTQTVECSQSGTAMLNSSDSDNSLEVWPGVFDQGVTSSALYKELLKNEQTNFSLVHAAVADLGGIPAMVHHSDMSNTIPDEKVVITFLSFLCARLLDLRKETRAARVIQTVWRNY-------------------------RLKVEKKLLEHKAARVIQRAVVQ-FLSRCRLQKRSHSAAVIQKYFRRYLAQRQLKELKALKHKELQDNATLIIQRFWKGYSARRRFIILRHSAICMQARVRAKIAQSSYKQIQQATVTLQSHMRAWLLGKKKRQEYLHIKSSVIIIQHAFTRW-KRQKQKRHTEAVLIIQKCYRRWKACKSMAQNM--AAIKIQSVYRMHRERQKFLDTKCKIIKIQSWFRCKKDREAFLMQKESILTLQKYYRAYKQGRLDRKKFLEMRSAAISIQAHYRGMRVRQLYYRIKAACVLQSYWRMRQ-EKKKYDHVKQLVVLLQSNVRKCQQQKQFKLMKRAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKAKLQVRSAVKI------------------------QALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQVHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCAR-------------------LQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVH-QYMAIRNAALCIQSAFR---GLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNF-------------------YQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLRER---------------EELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRYRSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNL 2707 HSP 2 Score: 363.614 bits (932), Expect = 4.980e-100 Identity = 439/1748 (25.11%), Postives = 786/1748 (44.97%), Query Frame = 1
Query: 2014 RAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFR-RYLVQKN---YLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQ---------------------------SAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRL----RSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRML---------------------------SLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRA--LIQRRKFQYLR--NAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXC----QSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKK----QIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMII----TKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYV----RRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFI----CQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFR----GFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQK-------AARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGI-FVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLKN--------ASIIISKHVRGV-----LVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-FIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK---AGVLNFDVIGSEFIKLVKNLLYRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKS 6873
RAA IQ +R +R F +++QS RR K ++ + I Q++ + Y AR R ++K+++I IQ +R R+RY ++ AT +Q FR + +QK Y+ + + + +Q +RG+ R + K+ I+Q + + +K++ L +A ++IQ +A+RGY R++ Q AA+ IQ+ +RS R+ YL +R+SV+ IQ+ RK +K+ R+ + +Q RG++ R+ + +A ++ F Y +KQ M+ + + +Q+ R + ++R + KSA +IQ ++ + + ++ A + A+ LIQ RA L Q ++F YLR +A ++Q +R + VR++ + +A IQ RS I K Y ++ + L IQ+H FL + + +R+ QS R ++++K+ L++++S I++Q+++RA+ RKQ+L + T ++Q + + R+ + IQ R + QR Y + ++A +Q ++R+ KE+ Q + AA +Q F+ ++ + +IQ++ + + R++F IL Q + RM + +++Y + A + + +G+ R++ +S VIQ +FR + + +++ +AIVIQ+ + + +RK Y Q + IQ RG RK L+ H++A+ IQ +R ++ R +I + A VIQ++FR + +R QY+ ++ V+ IQS R F + + + AT IQ K + R Y + + +IQ R + + + + + + R L+R K AAT IQ R Y RK ++ +AV IQ YRA R H+ + AA LQ RG R + +Q K F RK Y +L++S+I++Q+ +R G +KFLK ++A+ICIQ R + + + A+ IQ R + Y AA+++QRH+R+Y R LE K AA I+Q YRG R + N+ +Q Y++ + R+ Y +Q VR R R R ++ + +KY + AV IQ FR + + +A+I+IQ ++ + +R+E+ K + V IQ+ R + K ++ + +IQ R RL+ R ++L+I+ + I IQS +R ++ + ++ + R +I R++F++ KS ++IQ+ +R + ++S ++L +IF +R +LK Q + T + + G + R Y + +VI+LQ RG+L+RK + +K + I + G+ + HF++ ++ + L+ R A+ KIQ R Y+Q+RR S + Q WR +I K R+ R R R + K E ++ NR + A D S ++ +L L LE T LS C+ + +S A K + L+ CNR + +EV+ + V NL K ++V S I L ++R K KG +IF TC L+ + Q++
Sbjct: 1568 RAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKAKLQVRSAVKI-QALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQVHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCARLQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVHQYMAIRNAALCIQSAFRGLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNFYQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLREREELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRY---RSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNLRDMHNAATVVQAYYRMHRQRQYYFA-------LQHAVRTTQVRFRANRARVDAV------------KKYATIRMAVKRIQSAFRARKAARDAEK-DSAAIVIQAQWKMHTVRREYVKMTEAAVVIQAVFRGHRTRKMLKAMEVSACLIQAWYRSCRLTRLQ--------------------RAQYLSIRSAAITIQSAFRGMLAHR---VAEREQAASKAQWRGYIQRRKFVQYKSAALLIQQRYRAYRLQKS--QHLLHLIF----IRKHFVRLK-QAVVTLQMHFRAVKTGRYERIRYTQSRNAVIKLQACARGWLVRKEVMHIKQFFLVFFYFYYLYIKHQLLGIYPIAFIYYLHFRQKIVTLQRAIRAWLQLRNNAACKIQRSMRDYLQRRRQARAVSGIVKFQALWRGYICRKARDTKAVRVLRKRLQRVSQDVK----EEDKLCNRTVVA------------------LDYLLSSKHLSFILAALQHLEVATRLSAVCCENMAQSGAVKTIFVLIRSCNRSIPCMEVIKLSVMVLLNLSKYERTVQAVYEVENSVDILLDLMQIFREKAGDKVSDKGGSIFTKTCCLMAIFALHSQRA 3239
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Xenopus
Match: lrp8 (LDL receptor related protein 8 [Source:Xenbase;Acc:XB-GENE-980035]) HSP 1 Score: 560.451 bits (1443), Expect = 5.803e-161 Identity = 553/2164 (25.55%), Postives = 989/2164 (45.70%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIF------------------------NTHL-----SKTKVEDINKNMPIYIEATKLLLSECKV--------AIEKINSEVTKDSLKFKDD-IFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILVNIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYID---------------AVIDRDKLISEIKLFENPIXXXXXXXX-----------XXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLTS----------------------ANLFDKEI--------LLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKS---------ATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYL----ARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRS-SVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGY----LRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQY----YSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIK----MHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKS---------------------------YICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIA----ATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRA----HTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF-----NAHKKFLKLKNASICIQKNVRRYCQMKLYRD---TRNASIVIQKYVRGFL---------------------------CRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLI----RKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFR----RFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIF----VRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-----------FIVLKRSAVVIQRIWRGRQLRCHL 6384
D+ W+ +QE F WLN I N H + TK E K + +L S C++ AI ++ E+ L + D +K + + +++YN WL + ++ F +SL SN++ FI ++LWN DIA ++R + + + +L++ L++ L +++ LD AK+ + D LF KD+ K+S ++L F+ FL GEG++ + L VSH+QT +DE+DF V+NL+ D+ GVRL + + + + KLR PA+ +K N+E+A++A D G + G I I HRE+TLALLW ++ ++ + K ++ ++ NP S+ LL+ WV +VC Y+ V N + + DGR FC L+++Y P YL LN + TT T +FD+ + LL+NE+ NF + + + +GG P ++ N IP + ++ L+F +RL+DL RAA IQ VWR YR V + L +K K+ + + Q V ++L+R R+ K SA +IQK +RRYL + + +++K+ AT+++Q ++ Y ++ ++ + S + +Q +R + +S+YK+I+++T +Q +++ +L R++++ + ++++IQ AF + KR+ +A +IIQ YR C+ N+ + I IQ V ++K I IQ + R +R FL K ++ L+ Y+ Y L RK+FL+MR++ I +Q + R + +R + + + ++ R KK++ K +L+Q+ VR Q+++F+ ++ AA +IQ +R + K+ + ++ ++A+VIQ R + +K L+++ +V + Q+L R Y +K++L++++++I IQ FR R ++ RK T VQ+ + M + R+ ++ ++ I +Q +R RR KA +Q ++R ++KKQ L +AA ++Q+++++ Y +K + + + IQ R RK + + + V+ +Q R + ++ QKK AT+T+ +G+ RK+ + + I IQ++FR + +K ++K +A+ IQ+ R + +R+ Y + K +Q RG VRK L H+SA LIQ FYR + + + R A+ +IQ +R H + Q Y +K +QS R + ++ KAAT IQ + +I+ K+Y T R + + IQ++ +L + L R+ Y R + ++Q R ++VRKRI+ Q++ ++Q YRA +R ++ A LQ RG +R+N ++QS + R Y++LR ++ +VQ +R N H +++ ++NA++CIQ R +K+ RD A+ +IQ++ + FL R +Y R A ++LQ FR + RI+ +A +IQ +R + + + +++ + IQ +KA + RK YL+ RQ + IQ R R + + IQ R + +Y+K + AV IQ+ FR R SE + +K A + IQ +R + +RK+ + + + +IQS + + ++ ++SA +IQ R I R ++ ++ K + IQ R +VR + + IQSFYRM+ + K Y + Q++ IQ+ R AR + YQ + +Q+ RG ++ Q+M A IQ+ K + RK Y L+ S I +QR R ++ R+ FLK ++A+I I RG+ R E L+ R A+ +IQ+ FR + Q Y K ++IQ+ +R ++ L +A+++Q ++RG++ R +L
Sbjct: 684 DERWMAKQERGFTWWLNFILTPDDFAVKRDSSKVQAATLILGSENAHKVSVPKAPTKEEVSLKAYTTRCKLNRLRRSACRLFTSEPVVKAILRLEVEIEAQRLLVRRDRHLWKDIGERQKILNWLLSYNPLWL----RIGLETIFGELISLESNSDVTGLAVFILNRLLWNPDIAAEYRHPSVPNLYRDGHEEALSKFTLKKLLLLIFFLDHAKQFRLIDHDPCLFWKDAEYKTSKDLLLAFSRDFLSGEGDLSRHLGYLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVTVELLAQSWSLSKKLRVPAISRLQKMHNVEVALQALTDRGVLLKDERGVSITSKDIVDRHRERTLALLWKIVFSFQVNIFSLELRKVEIQILKESYNTQKQLAALRSLANPAPTQTRESDQFEPEKYNERVSLLMEWVNAVCRFYSTKVQNFTVSFSDGRVFCYLVNHYHPSYLPLNAVCQRTTQTVECSQSGTAMLNSSDSDNSLEVWPGVFDQGVTSSALYKELLKNEQTNFSLVHAAVADLGGIPAMVHHSDMSNTIPDEKVVITFLSFLCARLLDLRKETRAARVIQTVWRNYRL--------------------KVEKKLLERKHKAAR----VIQRAVVQFLSRCRLQKRSHSAAVIQKYFRRYLAQRQLKELKALKHKELQDNATLIIQRFWKGYSARRRFIILRHSAICMQARVRAKIAQSSYKQIQQATVTLQSHMRAWLLGKKKRQEYLHIKSSVIIIQHAFTRW-KRQKQKRHTEAVLIIQKCYRRWKACKSMAQNM--AAIKIQSVYRMHRERQKFLDTKCKIIKIQSWFRCKKDREAFLMQKESILTLQKYYRAYKQGRLDRKKFLEMRSAAISIQAHYRGMRVRQLYYRIKAACVLQSYWRMRQ-EKKKYDHVKQLVVLLQSNVRKCQQQKQFKLMKRAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKAKLQVRSAVKI------------------------QALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQVHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCAR-------------------LQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVH-QYMAIRNAALCIQSAFR---GLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNF-------------------YQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLRER---------------EELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRYRSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNL 2734 HSP 2 Score: 328.946 bits (842), Expect = 2.071e-89 Identity = 367/1483 (24.75%), Postives = 679/1483 (45.79%), Query Frame = 1
Query: 2014 RAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFR-RYLVQKN---YLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQ---------------------------SAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRL----RSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRML---------------------------SLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRA--LIQRRKFQYLR--NAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXC----QSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKK----QIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMII----TKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYV----RRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFI----CQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFR----GFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQK-------AARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVR----RYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRR----YICISKFKMIKSATLIIQKHIRGIFV------RLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRM----HYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMR-TATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRK 6078
RAA IQ +R +R F +++QS RR K ++ + I Q++ + Y AR R ++K+++I IQ +R R+RY ++ AT +Q FR + +QK Y+ + + + +Q +RG+ R + K+ I+Q + + +K++ L +A ++IQ +A+RGY R++ Q AA+ IQ+ +RS R+ YL +R+SV+ IQ+ RK +K+ R+ + +Q RG++ R+ + +A ++ F Y +KQ M+ + + +Q+ R + ++R + KSA +IQ ++ + + ++ A + A+ LIQ RA L Q ++F YLR +A ++Q +R + VR++ + +A IQ RS I K Y ++ + L IQ+H FL + + +R+ QS R ++++K+ L++++S I++Q+++RA+ RKQ+L + T ++Q + + R+ + IQ R + QR Y + ++A +Q ++R+ KE+ Q + AA +Q F+ ++ + +IQ++ + + R++F IL Q + RM + +++Y + A + + +G+ R++ +S VIQ +FR + + +++ +AIVIQ+ + + +RK Y Q + IQ RG RK L+ H++A+ IQ +R ++ R +I + A VIQ++FR + +R QY+ ++ V+ IQS R F + + + AT IQ K + R Y + + +IQ R + + + + + + R L+R K AAT IQ R Y RK ++ +AV IQ YRA R H+ + AA LQ RG R + +Q K F RK Y +L++S+I++Q+ +R G +KFLK ++A+ICIQ R + + + A+ IQ R + Y AA+++QRH+R+Y R LE K AA I+Q YRG R + N+ +Q Y++ + R+ Y ++ Q R R + ++ ++M+V IQ R R K A++ IQ ++ + + + + A+++IQ FR + RK K + IQ++ R + +++ I+SA + IQ RG+ K+ +V + +R F+ +K++++ +Q +R YE Y + ++ +Q R ++ RK + IK ++ F+ ++ S + L + F Q +V + A + ++R A IQ++++ Y R+ +++ Q RG++ RK
Sbjct: 1595 RAACVIQTYYRSHRATKQAVHRFKQMRHAAVVIQSAFRRMQARKAKLQVRSAVKI-QALSRSYFARKRFLEIKRASIKIQSAFRMRQRRVRYCALRKATFFVQQKFRAKKQMQKEREAYINMQVACIKVQAAVRGHFVRREIQSWHKAATILQAEYRMWRQKKQYKLLYRAAIIIQEHYRAHKMQVHQRAYFLAIKQSAVRLQAAYRGYTVRKSVKTQRLAALHIQTAFRSYRIRKNYLRMRQSVVTIQRWYRCKTSGRKEQKKYLEIQRATVTVQSAYRGWVTRKQVKVWNTAAICIQSAFRRYAAQKQIRTMKKAALTIQQRYRAVLAGRRERERYLKLCMSAKRVQAMWRGRAVRKDLERQHKSAALIQSFYRMHVCQTQYKAMRRASHLIQNFYRAHKLGQLQQFYYLRLKKSATVLQSAYRGWKVRRQMHSFHKAATTIQSAFRSFILHKRYHTLRTATLTIQRHYSAFLCARLQRTKYVRVRKSVIVLQSAFRSFMVRKRILRMQQSAIVVQRNYRALLTGRRVRKQYLELHRATCMLQAAWRGRKVRRNIKAMDKAATVIQSQYRMMRQRCYYRELREAARVVQLRYRASKERDRNVHQYMAIRNAALCIQSAFRGLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERINHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQSAVTIQATFRGMKERKMLSIMHKAASTIQASFRMHQCRSQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVRRNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNFYQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLREREELKLRHRAAAQIQSLFRMHRQHVSYLANKQAAVVIQRHYRRY---RSCKLEHKQYLKLCNAAIIVQALYRGKKSRKNLRDMHNAATVVQAYYRMHRQRQYYFALQHAVRTTQVRFRANRARVDAVKKYATIRMAVKRIQSAFRARKAARDAEKDSAAIV-IQAQWKMHTVRREYVKMTEAAVVIQAVFRGHRTRKMLKAMEVSACLIQAWYRSCRLTRLQRAQYLSIRSAAITIQSAFRGMLAHRVAEREQAASKVRSFLVMTPYLLHLIFIRKHFVRLKQAVVTLQMHFRAVKTGRYERIRYTQSRNAVIKLQACARGWLVRKEVMHIKQFFLVFFYFYYLYIKHHS-TKTLYYLHFRQKIVTLQRAIRAWLQLRNNAACKIQRSMRDYLQRRRQARAVSGIVKFQALWRGYICRK 3071
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Mouse
Match: Aspm (abnormal spindle microtubule assembly [Source:MGI Symbol;Acc:MGI:1334448]) HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0 Identity = 651/2423 (26.87%), Postives = 1090/2423 (44.99%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTH--LSKTKVEDIN----------------KNMPIYIE------------------ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFENPIXXXXXXXXXXXXV----------------------------WVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLTSA------------------------NLFDKEI-------LLENEKRNFQIFFSKLKQIGGAPIILPKE---NEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMK---------KSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSN----YKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCII-IQKYIR----GFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRK----FQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIK------QSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQK---NIRALL-QRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFK---------------------------SYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKK----YLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRK---------------------------IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYI----RQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIR----GYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDT---RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFR------KYLIIRRIDL------------EQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYI----SRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCY---------ILRKE-------------------FKKKRKNCVKI-----QSYIRR----YICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVR------------------TRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLS---IIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRK------------IFLKLKNASIIISKHVRGVLVRNHFQKNKQHMK--IFAQENLRKRLEASIKIQAYFR----------CYIQKRRYCLLKSYTLLIQQRWRFIVLKRS------AVVIQRIWRGRQLRCHLNAKKIGH-EISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK-----AGVLNFDVIGSEFIKLVKNLLYRNINSKR-GTKGITIFCHTCLLLVLLIKMEQ 6867
D+ W ++QE F WLN I KT V +N P E A L SE V AI+K+ E+ L KD +K + + +++YN WL + ++ F + L N++ FI ++LWN DIA ++R + + +L++ L++ L ++ LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + S L VSH+QT +DE+DF V+NL+ D+ GVRL R ++L N ++ KLR PA+ +K N++L ++ K G + G I + HREKTL LLW + +D ++ D+L EI ++ S+ S WV +VC YN V N + + DGR C LIH+Y P Y+ + I T+ + A D E LLENEK+NF + S + +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ K H K ++QS+V FL ++ + ++ Q +R A+ ++ +K KSA+LIQ +RRY R R+ ++K +V+LQS R + +Y + + + IQ + R YL R +++++ S+ +IQ + + R+K TKA V +Q AFR + R+ I+ ++AV+IQS+YR + Y+ +R VI+IQ+ V + +KL KR + I+ +QK+ R G + ++L+ ++A L+ F G R + + +LQ RM R FL +K I +Q ++Y +++ K A I IQT RA I R+ +Q R++ I++Q R RK F S I IQ R+ IC+K + K QS++ +++ K +L ++ I R Q L + +K+Y++VR+S I +Q HFR RKQ K I +Q Y +M RQ++LK+ + IQ RA + QR+ +++ K+A I +Q +R CK ++QI + AA +Q+ F+ +Y + QF K +E+V +Q R R+Q +++ + + +QS RM + +++Y+ AA I + V+ A K+ Y+ RH+ +V Q +++ M R+ A +IQ Y R I+R+ +Y A+ +Q RG VRK + H++A IQ +R+Y+ +K + R +AIVIQ+ +R I Q+Y R+ + +Q+ R ++ + M AAT I+ + K R +Y+ R +A+IIQ R Y Y+ + + Y R L A +Q RG VR+ + A +IQ+ +R H +++F + AA +Q+ R G + ++ R ++L+Q+ +G R+ + + ++ ++Q+ FR F +KFL L+ +I IQ+ R K R A I IQ RG++ R + Q+ AA ++Q FR +Y ++R + ++ AA I+Q RG R+H +S IQ+ F+A+++R++++ +R+ IF+Q R + ++FL+L+ + I IQ R +K + +A IQ FR F K ASI IQ+ +R Y ++R+E F ++R+ K+ ++ RR Y+C K T ++Q H +G+ + ++ + QK+ RA R ++L+ ++ IQ++YR +K Y + +++ +I+ +AR+RFL++++ IIIQ+ +R L+ R + NL +Q+ RG A+ + + R+A ++IQ+ V+ K +I L+KS + +Q +RG+L+RK F + K R + + K+HM IF Q RKRL+ I+ Y + C++Q+ R + +++ + RF++ +R A IQ +WRG R KK H EI IR + + N + ++AL L LT ++ +L L LE VT LS C+ + ES A + ++ CNR V +EVV + V N+ K A V + ++L++ +YR R K +IF TC LL +L+K EQ
Sbjct: 660 DERWKEKQEQGFTWWLNYILTPDDFTVKTNVSKVNAASLVLGAESQHKISVPKAPTKEEVSLRAYTASCRLNRLRRTACSLFTSEKMVKAIKKVEIEIEVGRLLVRKDRHLWKDIGQRQKVLNWLLSYNPLWL----RIGLETVFGELIPLADNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPLLFRDGHEAALSKFTLKKLLLLICFLDHAKISRLIDHDPCLFCKDAEFKASKELLLAFSRDFLSGEGDLSRHLSFLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVRTVELLTQNWNLSDKLRIPAISRVQKMHNVDLVLQVLKSRGVPLTDEHGSAISSKDVVDRHREKTLGLLWKIALAFQVDISLNLDQLKEEIDFLKHTHSIKRAMSALTCPSQAITNKQRDKRISGNFERYGDSVQLLMDWVNAVCAFYNKKVENFTVSFSDGRILCYLIHHYHPCYVPFDAICQRTSQSVACAQTGSVVLNSSSESEGGCLDLSLEALDHESTPEMYKELLENEKKNFHLVRSAARDLGGIPAMIHHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKRDLK-HHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAYWRRYSTRKRFLRLKHYSVILQSRIRMKIALTSYKRYLWATVTIQRHWRAYLSRKRDQQIFRKLKSSSLVIQFMFRRW-KRRKLQLQTKAAVTLQRAFREWHLRKQ--IRERSAVVIQSWYRMHRELQKYIYIRSCVIVIQRRV-RCFQAQKLYKRRKDAILTLQKHYRARQKGKLAHADYLQKRAATIRLQAAFRGMKARHSYRLQIGAACVLQSYWRMRQERVRFLNLKKMVIKLQAHIRKYQQLQKYKKIKKAAITIQTHFRASISARRVLASYQKTRSSVIVLQSACRGMQARKAFRHALASVIKIQSYYRAYICRKTFQNFKNATIKLQSIVKMKQSRKQYLQIRAAALFIQRWYRSQKLASQK--RKEYIQVRESCIKLQSHFRGCLVRKQLRLQCKAAISLQSYFRMRTARQRYLKMCKAALVIQSFYCAYRAQISQRKNFLQVKRAAICLQAAYRGCKVRRQIKQQSTAAVTIQRVFRGHSQRMKYQTMLQSAVKIQRWYRAQKVAYDMRIQFLKTREAVVCLQSAYRGWQVRQQLRRQHEAAVKIQSTFRMAVAQQQYKLLRAAAAVIQQHVRARAAGKRQHLAYIQLRHAALVFQAAWKGKMLRRQIARQHQCAALIQSYYRMHIQRRKWSIMKTAALQIQLCYRAYKVGKEQRHLYLKTKAAVVTLQSAYRGMKVRKRVAECHKAAVTIQSKFRAYRTQKKYTTYRTSAIVIQRWYRNIKITTQQHQEYLNLRRAAVQVQAAYRGIRVRRRIQHMHMAATLIEAMFKMRQSRVRYLKMRTAALIIQVRYRAY------------------YLGK-IQHEKYLRTLKAIKTLQAGVRGARVRRTVRKMHFAATLIQSHFRGHRQQTYFHRLRKAATMVQQRYRAVKEGSAEFQRYSRLRRSVLLIQAAFRGLRTRRHLKAMHLAATLIQRRFRTFAMRRKFLSLRKTAIWIQRQYRARLYAKYSRQQLLLEKAVIKIQSSYRGWVVRKRVQKMHRAATVIQATFRMHGAYMRYQHLKRASVVIQVHTAAELQRQKHAAVILQAAVRGMKTRSHLKTMHSSATLIQSQFRAFIVRRRFIALRKAAIFVQRKFRATLYAKHKLHQFLQLRKAAITIQSSYRRLMVQKKLQEMHRAAALIQATFRMHRTYVAFHIWKCASIRIQQCYRTYRTIKLQKEKLIREEQHSAAVLIQSTYRMYRQRCFYQQRRWAAKVIQKTYRANKRRQDLLYVC-------KEETPLLQMHFQGLNTAKQGRQQHGAAMITQKHFRAFKARRLMEAERGFQAGCRKYKAKKYLSKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLSVRGARENLKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQERIKYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLFHFTAAAYCHMCALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRFIEQYHKILSTRREAHACWLQQDR-----AASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWR-----KKNDHTEIKAIRRSLRAVSTTVEEENKLYRRTERALHHL----LTYKHLSAILDALKHLEVVTRLSPLCCENMAESGAVSTIFVVIRSCNRSVPCMEVVGYAVQVLLNVAKYDKTIAAVYEAENCVDTLLELLQ--VYREKPGDRVAEKSASIFTRTCCLLAVLLKTEQ 3029
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Mouse
Match: Aspm (abnormal spindle microtubule assembly [Source:MGI Symbol;Acc:MGI:1334448]) HSP 1 Score: 286.189 bits (731), Expect = 7.284e-77 Identity = 262/978 (26.79%), Postives = 433/978 (44.27%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTH--LSKTKVEDIN----------------KNMPIYIE------------------ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFENPIXXXXXXXXXXXXV----------------------------WVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLTSA------------------------NLFDKEI-------LLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMK---------KSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYL---ARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVVHKVLFKRKL-EKRLRS-------------CII-IQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKK 3114
D+ W ++QE F WLN I KT V +N P E A L SE V AI+K+ E+ L KD +K + + +++YN WL + ++ F + L N++ FI ++LWN DIA ++R + + +L++ L++ L ++ LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + S L VSH+QT +DE+DF V+NL+ D+ GVRL R ++L N ++ KLR PA+ +K N++L ++ K G + G I + HREKTL LLW + +D ++ D+L EI ++ S+ S WV +VC YN V N + + DGR C LIH+Y P Y+ + I T+ + A D E LLENEK+NF + S + +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ K H K ++QS+V FL ++ + ++ Q +R A+ ++ +K KSA+LIQ R+Y + K+++A + Q+ +RR+ K YL + +++ II+ + L R + ++R + IIQ+ + L ++ +K +A VIQ+ FRGY R+++ Q A +IIQ R+ V R Y+ L+KS +++Q +V L ++++ E++ ++ C + IQ+ R + RN K +V ++ +F L+RK+F++ + ++ R A ++ + A +IQ VR + R+ + + + A IQ +R YS RKK
Sbjct: 660 DERWKEKQEQGFTWWLNYILTPDDFTVKTNVSKVNAASLVLGAESQHKISVPKAPTKEEVSLRAYTASCRLNRLRRTACSLFTSEKMVKAIKKVEIEIEVGRLLVRKDRHLWKDIGQRQKVLNWLLSYNPLWL----RIGLETVFGELIPLADNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPLLFRDGHEAALSKFTLKKLLLLICFLDHAKISRLIDHDPCLFCKDAEFKASKELLLAFSRDFLSGEGDLSRHLSFLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVRTVELLTQNWNLSDKLRIPAISRVQKMHNVDLVLQVLKSRGVPLTDEHGSAISSKDVVDRHREKTLGLLWKIALAFQVDISLNLDQLKEEIDFLKHTHSIKRAMSALTCPSQAITNKQRDKRISGNFERYGDSVQLLMDWVNAVCAFYNKKVENFTVSFSDGRILCYLIHHYHPCYVPFDAICQRTSQSVACAQTGSVVLNSSSESEGGCLDLSLEALDHESTPEMYKELLENEKKNFHLVRSAARDLGGIPAMIHHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKRDLK-HHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAGCRKYKAKKYLSKVEAACRI-QAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLSVRGARENLKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQERIKYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLFHFTAAAYCHMCALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRFIEQYHKIL----------------------------STRREAHACWLQQDRAASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWRKK 1603 HSP 2 Score: 134.035 bits (336), Expect = 1.697e-30 Identity = 149/545 (27.34%), Postives = 253/545 (46.42%), Query Frame = 1
Query: 5410 ASIIIQKNFRCYILRKEFK---KKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVR-----LKYKKIIKL----VVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLS---IIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRK------------IFLKLKNASIIISKHVRGVLVRNHFQKNKQHMK--IFAQENLRKRLEASIKIQAYFR----------CYIQKRRYCLLKSYTLLIQQRWRFIVLKRS------AVVIQRIWRGRQLRCHLNAKKIGH-EISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK-----AGVLNFDVIGSEFIKLVKNLLYRNINSKR-GTKGITIFCHTCLLLVLLIKMEQ 6867
A+ +IQ +R Y L+++ K ++ K IQS + ++ + + SA L+IQK R + + LK +K+ KL V IQ R + ++L+ ++ IQ++YR +K Y + +++ +I+ +AR+RFL++++ IIIQ+ +R L+ R + NL +Q+ RG A+ + + R+A ++IQ+ V+ K +I L+KS + +Q +RG+L+RK F + K R + + K+HM IF Q RKRL+ I+ Y + C++Q+ R + +++ + RF++ +R A IQ +WRG R KK H EI IR + + N + ++AL L LT ++ +L L LE VT LS C+ + ES A + ++ CNR V +EVV + V N+ K A V + ++L++ +YR R K +IF TC LL +L+K EQ
Sbjct: 1237 AARLIQTTWRKYKLKRDLKHHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAGCRKYKAK-KYLSKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLSVRGARENLKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQERIKYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLFHFTAAAYCHMCALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRFIEQYHKILSTRREAHACWLQQDR-----AASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWR-----KKNDHTEIKAIRRSLRAVSTTVEEENKLYRRTERALHHL----LTYKHLSAILDALKHLEVVTRLSPLCCENMAESGAVSTIFVVIRSCNRSVPCMEVVGYAVQVLLNVAKYDKTIAAVYEAENCVDTLLELLQ--VYREKPGDRVAEKSASIFTRTCCLLAVLLKTEQ 1764 HSP 3 Score: 90.5077 bits (223), Expect = 2.760e-17 Identity = 101/371 (27.22%), Postives = 178/371 (47.98%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFT--ETRNKII-LVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKN---------ASICIQKNVRRY------------CQMK-LYRDTR---------NASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIR--RIDLE-QKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRK----KYLEIRQKTIFIQCLVRRYISRNRFLRLK---------------MSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKE-----FKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRG 5580
AA +Q R Y ++++ + R+K ++QS++ F++R+ QK S+++++QK +R +A +K LKN +++ IQ R+Y C+++ YR R A +I+ Y+ L R ++ + AAII+QR +R L +R R +L+ +AA +IQ +RGY R FL Q+++ + IQ + +A + K KY+++++ T+ +Q LVR ++ R R K M + IQ+ R + T R K +VI IQ+ FR+ + K F I++ + R+E ++ R V IQ +RR++ + + I S IQ RG
Sbjct: 1237 AARLIQTTWRKYKLKRDLKHHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAGCRKYKAKKYLSKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLSVRGARENLKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQERIKYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLFHFTAAAYCHMCALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRF---------IEQYHKILSTRREAHACWLQQDRAASV-IQKAVRRFLLCRRQEKITSCATRIQALWRG 1597 HSP 4 Score: 86.2705 bits (212), Expect = 5.608e-16 Identity = 108/420 (25.71%), Postives = 182/420 (43.33%), Query Frame = 1
Query: 2509 KAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLR---------KSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLR-MLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSY-ICKKQFRKMKESVTVIQKYQRRLICRKQ 3735
KA VIQS + RR + AA++IQ +R +R L+ KS ++IQ K K+ L K +C I Q + R + + +L AVNI+E Y L R++FLKMR + I++Q+ R LS+R + +E + + A +IQ R R+ F R+A +IIQ+ R A+V K R Y+K+K+S +V+Q +LVR +L++K+ + + T + HF A + + +Q+ ++H + K VI IQ+ R LQR+R+I+ ++ +R+ +C + ++AA+V+QK + + +C++Q K+ T IQ R RK+
Sbjct: 1262 KAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAGCRKYKAKKYLSKVEAACRI-QAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLSVRGA---------------------RENLKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVR--------------AMVAAKQERI-----KYIKLKKSTVVVQ-----------------------ALVRGWLVRKRVSEQKAKTRLF--HFTAAAY------CHMCALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRFIEQYHKILSTRREAHAC-----WLQQDRAASVIQKAVRRFLLCRRQ-EKITSCATRIQALWRGYSWRKK 1603 HSP 5 Score: 85.5001 bits (210), Expect = 9.854e-16 Identity = 96/428 (22.43%), Postives = 203/428 (47.43%), Query Frame = 1
Query: 3511 LLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQF-----QKEMKL----VILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARK 4767
LL R+ I+ + + RK++ ++ K ++AA V+Q +++ +++ +K + VIQK RR+ +++ +K KL +L+Q+ R KK Y K+ A I + + + A KKYL+ +V +I+ + R+ FL ++ +AI+IQ+ R T +++ ++N++ H++A +IQ +R Y+ R++F+ +R+A ++IQ+ ++R ++++ KY ++KK+ +Q + +G+++RK+ Q+ + Y ++ I + Y +R+ K+ + + IQ+ R L RKR + ++ +I+ AH ++ Q AA +QK +R +L+ + + + +Q+L +G+ RK
Sbjct: 1228 LLDLRKEIRAARLIQTTWRKYKLKRDLKHHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAGCRKYKAKK-YLSKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRA----------TLSVRGARENLK----------RHRAACVIQAHFRGYQARQSFLQQRSAVLIIQR-----HVRAMVAAKQERI--------------KYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLFHFTAAAYC-------HMCALKIQRAYRLHVTLRNA-KKHMDSVIFIQRWFRKRLQRKRFI--EQYHKILSTRREAHAC---WLQQDRAASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWRK 1602 HSP 6 Score: 85.1149 bits (209), Expect = 1.186e-15 Identity = 104/413 (25.18%), Postives = 179/413 (43.34%), Query Frame = 1
Query: 2995 ATILIQTKVRALIQRRKFQYLRN---AAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFR---SCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQ----FQKEMKLVILLQSKIRMIITKKRYQKKIAAT---------------LTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRK----IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRK 4146
A LIQT R +R ++ + AA +IQ + R++ +A+VIQK R + Q+ +K L ++ L+ Q+ RKY K+YL ++ IQ +R A K++L K +++ Y+ A L RRR++K + A I IQRK+R S + ++ + ++AA V+Q +F+ Y ++ F + + +V +IQ++ R ++ KQ + K K +++Q+ +R + +KR ++ A T L I + + + + + SVI IQ FR + RK F I++Y + R+ + Q A VIQK +R FL+ + AT IQ +R Y RK
Sbjct: 1237 AARLIQTTWRKYKLKRDLKHHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLI--------------QAGCRKYK-AKKYLSKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLS-----------------------AQLARRRFLKMRAAAIIIQRKWRATLSVRGARENLKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQERIKYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLFHFTAAAYCHMCALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRF---------IEQYHKILSTRREAHACWLQQDRAASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWRK 1602 HSP 7 Score: 81.6481 bits (200), Expect = 1.663e-14 Identity = 94/342 (27.49%), Postives = 170/342 (49.71%), Query Frame = 1
Query: 2995 ATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFL---------IQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRA-ISARKQFLNFRKF--TIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALL----QRRRYIKNKKAVIFIQ--------RKFRSCKEKKQIILNNQAATV-------VQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQF----------QKEMKLVILLQSKIRMIITKK-------RYQKKIAATLT-ISKFVKGYFARKK 3873
A +IQ+ V + RR+ Q +AA++IQK +R S ++K +Q SA++IQ R +K YL ++ IQ + + K Y ++ + I + + L ++++LK+R + IIIQ+ +RA +S R N ++ V+Q + + +Q RQ FL+ +S V+ IQ+++RA++ +R +YIK KK+ + +Q RK S ++ K + + AA +Q+ ++ ++ + +K +SV IQ++ R+ + RK+F ++E L Q + +I K R Q+KI + T I +GY RKK
Sbjct: 1263 AARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAGCRKYKAKK-YLSKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLSVRGARENLKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQERIKYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLFHFTAAAYCHMCALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRFIEQYHKILSTRREAHACWLQQDRAASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWRKK 1603 HSP 8 Score: 77.411 bits (189), Expect = 2.879e-13 Identity = 123/518 (23.75%), Postives = 219/518 (42.28%), Query Frame = 1
Query: 4147 NFICKR--------NAAIVIQKQFRKHYIR---QQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVT---------QRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYR----DTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRK-----EFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKII 5613
+F+C R AA +IQ +RK+ ++ + + E K IQS++ F++ ++ ++ AA IQK + ++K Q +SAV+IQ R+Y ++K Y K+ AA IQ R + K+ + KAV II+ + A R F+ + AAI +Q+ R L ++G AR+ ++ R++ +I Q FRG+ A + FL+ ++A + IQ++VR K R + +++V+Q VRG+L R + Q + HF L+ IQ YR + VT++N KK+++ IFIQ R+ + R RF+ ++ ++ H +++Q +A IQK RRF + + + + + IQ +R Y RK E K R++ + + + + + L+ KH+ I LK+ +++
Sbjct: 1222 SFLCARLLDLRKEIRAARLIQTTWRKYKLKRDLKHHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAGCRKYKAKK------------------------YLSKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLS-----------------VRG--ARENLKRHRAACVI-QAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQERIKYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLF--HFTAAAYCHMCALK------IQRAYRLH-------------VTLRNA-------KKHMD---SVIFIQRWFRKRLQRKRFIEQYHKILSTRRE-----AHACWLQQDRAASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWRKKNDHTEIKAIRRSLRAVSTTVEEENKLYRRTERALHHLLTYKHLSAILDALKHLEVV 1659 HSP 9 Score: 74.7146 bits (182), Expect = 1.698e-12 Identity = 106/434 (24.42%), Postives = 190/434 (43.78%), Query Frame = 1
Query: 3733 QFQKEMKLVILLQSKIRMIITK---KRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQ---MKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARK----CYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAI 5004
+KE++ L+Q+ R K K +Q++ A I V + +R++ + +VIQ +R + SA Q+ LR K+ Q + +IQ R + +K L S ++A IQ +YR ++ K ++ A +I+ R+++ + R I IQ R ++++ ++ +AA IQ +GY R+ ++ QR + +IIQ++VR ++ K R Y + + ++Q + RG+LVRKR V EQKA + +F A +C A+K+Q+ R ++ +N + + +I +Q + + RK Y K+ S+ AH +L+ A+ IQK VRR+ + + + IQ RG+ R K + AI
Sbjct: 1230 DLRKEIRAARLIQTTWRKYKLKRDLKHHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWR-----------RVSA---QRKLRMLKNEKLAKLQNKSAVLIQAGCRKYKAKKYL-SKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLSVRGARENLKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQE-------------------RIKYIKLKKSTVVVQALVRGWLVRKR-VSEQKAKTRLFHFTAAAYC---HMC----ALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRFIEQYHKILSTR---------REAHACWLQQDRAASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWRKKNDHTEIKAI 1612
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Mouse
Match: Myo5b (myosin VB [Source:MGI Symbol;Acc:MGI:106598]) HSP 1 Score: 78.9518 bits (193), Expect = 9.283e-14 Identity = 61/215 (28.37%), Postives = 104/215 (48.37%), Query Frame = 1
Query: 2176 ICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK--KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYF 2814
IC+SV++ + + ++ I + YL ++R +K + AT+ +IQ ++RG+L R Y+R+R +T +Q++ +GYLAR+ + ++ T+A +V Q +R RR Y +A VIIQSF R+ RR Y +VL + K IIQKY RG++ R+ FL+ + A +++ F
Sbjct: 725 ICKSVLESLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFREATI-----------------------MIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNY--------------RQVLMEHK-------ATIIQKYARGWMARKRFLRERDAAIVIQCAF 895 HSP 2 Score: 70.8626 bits (172), Expect = 2.781e-11 Identity = 55/184 (29.89%), Postives = 94/184 (51.09%), Query Frame = 1
Query: 4846 KLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCR--IKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHF--LCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTR-GYFTHRKYVKQKKAVINIQKNFRRFSE 5382
K + A+I IQK+VR + Q YR R A++ +Q++ RG+L R ++ R+ AAI+ Q+ +R R +A IIQ+F R +R ++ + ++ IQ Y + ++ RK++L R I IQC RR +R LK+ + + R K V+ ++ + + K F+ SE
Sbjct: 764 KFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSE 947 HSP 3 Score: 65.4698 bits (158), Expect = 1.115e-9 Identity = 46/158 (29.11%), Postives = 81/158 (51.27%), Query Frame = 1
Query: 3751 KLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARK--KYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQ 4218
+ I++Q +R + + +Y++ AATL++ +F +GY AR+ ++L + IV Q +R R+ + + + ++IQ + R R+ Y R+ L H AT+IQ + R + RK F+ +R+AAIVIQ FR+ RQ+
Sbjct: 767 EATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNY-------------------RQVLMEH--KATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQE 903 HSP 4 Score: 64.6994 bits (156), Expect = 1.863e-9 Identity = 47/146 (32.19%), Postives = 76/146 (52.05%), Query Frame = 1
Query: 3961 SAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQ--MKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQ 4392
+ I+IQK +RG+++R Y A +Q+ RG+L R+ L +H R+ AAIV QKQ+R R+ Y + + IQS R + Y+Q M+ AT IQK A+G++ RK+++ +R +A++IQ
Sbjct: 768 ATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARR----------LAEHLRRT-----------RAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQ 892 HSP 5 Score: 62.003 bits (149), Expect = 1.390e-8 Identity = 45/149 (30.20%), Postives = 80/149 (53.69%), Query Frame = 1
Query: 5440 CYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVR--LKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQ--LMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRS 5874
Y+ + K R+ + IQ +R ++ K++ +++ATL +Q+ RG R ++ + + + QK R R + + ++ + IQSF R + +NY+ LM+ T+IQK R ++ARKRFL + I+IQ FRR A++
Sbjct: 755 AYLEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQE 903 HSP 6 Score: 61.6178 bits (148), Expect = 1.865e-8 Identity = 55/166 (33.13%), Postives = 88/166 (53.01%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY--CLLKSYTLLIQQ-------RWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKI 6399
L KL+ K R ATI+IQK+V+G+ R Y+ L+ + + LQRF RG+L R++ L + R +V FQ KQ+ + A+ R+ A++ IQ++ R +R Y L++ +IQ+ R RF+ + +A+VIQ +R + R L A KI
Sbjct: 757 LEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHL--------RRTRAAIV---FQ--KQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKI 909 HSP 7 Score: 60.4622 bits (145), Expect = 4.217e-8 Identity = 40/132 (30.30%), Postives = 75/132 (56.82%), Query Frame = 1
Query: 4645 KNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSS--SIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDT--RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRK 5028
+ A I +QK++RG+L R + R + +Q +G++AR+ + LR + +I+ QK +R A + + ++ A++ IQ R + YR + + +IQKY RG++ R ++ R+ AAI++Q FR+
Sbjct: 766 REATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRR 897 HSP 8 Score: 57.3806 bits (137), Expect = 3.199e-7 Identity = 53/164 (32.32%), Postives = 84/164 (51.22%), Query Frame = 1
Query: 2989 KSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRK--KFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLK 3474
+ ATI+IQ VR +QR K++ LR A + +Q+ R Y R+ + L + +AIV QK R + ++ Y ++ ++ ++IQ T+ V+ R Y +Q L K+T IIQK+ R ARK+FL R IV+Q + + RQ+ LK
Sbjct: 766 REATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVR-----------------RNY---RQVLMEHKAT-IIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALK 908 HSP 9 Score: 55.8398 bits (133), Expect = 8.846e-7 Identity = 48/159 (30.19%), Postives = 81/159 (50.94%), Query Frame = 1
Query: 2686 LFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK--QFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQ--YLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQ 3150
L K + +K + I+IQK +RG++ R + + ++A L+ + GYL R+ + L+ + I+ QK RML R ++ R + AT++IQ+ RA+ RR ++ + + A IIQK R + RK+FL + +AIVIQ
Sbjct: 757 LEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAY---------------RRVCR--------ATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQ 892 HSP 10 Score: 55.4546 bits (132), Expect = 1.167e-6 Identity = 51/173 (29.48%), Postives = 98/173 (56.65%), Query Frame = 1
Query: 4231 RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRK--KYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLA--ATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQ 4737
R+ I IQ +R ++ KY++++ A +Q+ +GY+ R+ +++ + R+A++ QK R +R++++ + +IIQ + R +R Y++ L+ AT+IQK ARG++ RKR + E+ A +IQ +R R Q+ A+K++ +L R N NK++ +Q
Sbjct: 766 REATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKAR-----QELKALKIEARSAEHLKRLNVG-MENKVVQLQ 932 HSP 11 Score: 55.0694 bits (131), Expect = 1.541e-6 Identity = 45/169 (26.63%), Postives = 86/169 (50.89%), Query Frame = 1
Query: 3466 KLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRS--CKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSA 3966
K + I IQK++R LQR +Y + + A + +QR R + + + +AA V QK ++ ++ +R++ + +IQ + R + R+ +++ +L++ K AT+ I K+ +G+ ARK++L R + IVIQ +FR R+ ++K A
Sbjct: 764 KFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQ-----VLMEHK---------------ATI-IQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKIEA 911 HSP 12 Score: 55.0694 bits (131), Expect = 1.808e-6 Identity = 36/132 (27.27%), Postives = 75/132 (56.82%), Query Frame = 1
Query: 3400 FRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRR--RYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRK--MKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIR 3783
FR+ TI++QK ++ R K+ +L++ +++Q+ R L RR +++ +A I Q+++R K ++ +A ++Q + ++ ++ +R+ M+ T+IQKY R + RK+F +E I++Q R
Sbjct: 765 FREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFR 896
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Mouse
Match: Myo5b (myosin VB [Source:MGI Symbol;Acc:MGI:106598]) HSP 1 Score: 78.9518 bits (193), Expect = 9.313e-14 Identity = 61/215 (28.37%), Postives = 104/215 (48.37%), Query Frame = 1
Query: 2176 ICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK--KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYF 2814
IC+SV++ + + ++ I + YL ++R +K + AT+ +IQ ++RG+L R Y+R+R +T +Q++ +GYLAR+ + ++ T+A +V Q +R RR Y +A VIIQSF R+ RR Y +VL + K IIQKY RG++ R+ FL+ + A +++ F
Sbjct: 725 ICKSVLESLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFREATI-----------------------MIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNY--------------RQVLMEHK-------ATIIQKYARGWMARKRFLRERDAAIVIQCAF 895 HSP 2 Score: 70.8626 bits (172), Expect = 3.008e-11 Identity = 55/184 (29.89%), Postives = 94/184 (51.09%), Query Frame = 1
Query: 4846 KLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCR--IKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHF--LCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTR-GYFTHRKYVKQKKAVINIQKNFRRFSE 5382
K + A+I IQK+VR + Q YR R A++ +Q++ RG+L R ++ R+ AAI+ Q+ +R R +A IIQ+F R +R ++ + ++ IQ Y + ++ RK++L R I IQC RR +R LK+ + + R K V+ ++ + + K F+ SE
Sbjct: 764 KFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSE 947 HSP 3 Score: 65.4698 bits (158), Expect = 1.147e-9 Identity = 46/158 (29.11%), Postives = 81/158 (51.27%), Query Frame = 1
Query: 3751 KLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARK--KYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQ 4218
+ I++Q +R + + +Y++ AATL++ +F +GY AR+ ++L + IV Q +R R+ + + + ++IQ + R R+ Y R+ L H AT+IQ + R + RK F+ +R+AAIVIQ FR+ RQ+
Sbjct: 767 EATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNY-------------------RQVLMEH--KATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQE 903 HSP 4 Score: 64.6994 bits (156), Expect = 1.981e-9 Identity = 47/146 (32.19%), Postives = 76/146 (52.05%), Query Frame = 1
Query: 3961 SAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQ--MKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQ 4392
+ I+IQK +RG+++R Y A +Q+ RG+L R+ L +H R+ AAIV QKQ+R R+ Y + + IQS R + Y+Q M+ AT IQK A+G++ RK+++ +R +A++IQ
Sbjct: 768 ATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARR----------LAEHLRRT-----------RAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQ 892 HSP 5 Score: 62.003 bits (149), Expect = 1.347e-8 Identity = 45/149 (30.20%), Postives = 80/149 (53.69%), Query Frame = 1
Query: 5440 CYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVR--LKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQ--LMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRS 5874
Y+ + K R+ + IQ +R ++ K++ +++ATL +Q+ RG R ++ + + + QK R R + + ++ + IQSF R + +NY+ LM+ T+IQK R ++ARKRFL + I+IQ FRR A++
Sbjct: 755 AYLEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQE 903 HSP 6 Score: 61.2326 bits (147), Expect = 2.346e-8 Identity = 53/168 (31.55%), Postives = 86/168 (51.19%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKI--FLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY--CLLKSYTLLIQQ-------RWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKI 6399
L KL+ K R ATI+IQK+V+G+ R Y+ L+ + + LQRF RG+L R++ L+ A+I+ K R + R + R+ A++ IQ++ R +R Y L++ +IQ+ R RF+ + +A+VIQ +R + R L A KI
Sbjct: 757 LEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAY---------------RRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKI 909 HSP 7 Score: 60.4622 bits (145), Expect = 4.371e-8 Identity = 40/132 (30.30%), Postives = 75/132 (56.82%), Query Frame = 1
Query: 4645 KNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSS--SIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDT--RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRK 5028
+ A I +QK++RG+L R + R + +Q +G++AR+ + LR + +I+ QK +R A + + ++ A++ IQ R + YR + + +IQKY RG++ R ++ R+ AAI++Q FR+
Sbjct: 766 REATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRR 897 HSP 8 Score: 57.3806 bits (137), Expect = 3.428e-7 Identity = 53/164 (32.32%), Postives = 84/164 (51.22%), Query Frame = 1
Query: 2989 KSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRK--KFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLK 3474
+ ATI+IQ VR +QR K++ LR A + +Q+ R Y R+ + L + +AIV QK R + ++ Y ++ ++ ++IQ T+ V+ R Y +Q L K+T IIQK+ R ARK+FL R IV+Q + + RQ+ LK
Sbjct: 766 REATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVR-----------------RNY---RQVLMEHKAT-IIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALK 908 HSP 9 Score: 55.8398 bits (133), Expect = 8.790e-7 Identity = 48/159 (30.19%), Postives = 81/159 (50.94%), Query Frame = 1
Query: 2686 LFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK--QFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQ--YLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQ 3150
L K + +K + I+IQK +RG++ R + + ++A L+ + GYL R+ + L+ + I+ QK RML R ++ R + AT++IQ+ RA+ RR ++ + + A IIQK R + RK+FL + +AIVIQ
Sbjct: 757 LEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAY---------------RRVCR--------ATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQ 892 HSP 10 Score: 55.4546 bits (132), Expect = 1.327e-6 Identity = 51/173 (29.48%), Postives = 98/173 (56.65%), Query Frame = 1
Query: 4231 RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRK--KYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLA--ATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQ 4737
R+ I IQ +R ++ KY++++ A +Q+ +GY+ R+ +++ + R+A++ QK R +R++++ + +IIQ + R +R Y++ L+ AT+IQK ARG++ RKR + E+ A +IQ +R R Q+ A+K++ +L R N NK++ +Q
Sbjct: 766 REATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKAR-----QELKALKIEARSAEHLKRLNVG-MENKVVQLQ 932 HSP 11 Score: 55.0694 bits (131), Expect = 1.505e-6 Identity = 45/169 (26.63%), Postives = 86/169 (50.89%), Query Frame = 1
Query: 3466 KLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRS--CKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSA 3966
K + I IQK++R LQR +Y + + A + +QR R + + + +AA V QK ++ ++ +R++ + +IQ + R + R+ +++ +L++ K AT+ I K+ +G+ ARK++L R + IVIQ +FR R+ ++K A
Sbjct: 764 KFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQ-----VLMEHK---------------ATI-IQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKIEA 911 HSP 12 Score: 55.0694 bits (131), Expect = 1.751e-6 Identity = 36/132 (27.27%), Postives = 75/132 (56.82%), Query Frame = 1
Query: 3400 FRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRR--RYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRK--MKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIR 3783
FR+ TI++QK ++ R K+ +L++ +++Q+ R L RR +++ +A I Q+++R K ++ +A ++Q + ++ ++ +R+ M+ T+IQKY R + RK+F +E I++Q R
Sbjct: 765 FREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFR 896
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Mouse
Match: Myo5c (myosin VC [Source:MGI Symbol;Acc:MGI:2442485]) HSP 1 Score: 76.2554 bits (186), Expect = 7.100e-13 Identity = 50/172 (29.07%), Postives = 91/172 (52.91%), Query Frame = 1
Query: 5209 IFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL--VVFIQKNIRANIVRTRFLNIKKSIINIQSFYRM 5718
IF + Y+ + R +L+ I+IQK RG+ RK++++++A + IQ+ FR ++K L++ + + +Q Y R Y+ + +++I+ AT+ IQ H RG R +Y+K+++ V +QK RA + R RF NI++ ++NIQ YR+
Sbjct: 738 IFFRAGQVAYLEKLRLDKLRQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFR-------------GQQTVRKAITATALKEAWA-----AIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVILQKYARAWLARRRFQNIRRFVLNIQLTYRV 891 HSP 2 Score: 71.633 bits (174), Expect = 1.530e-11 Identity = 54/179 (30.17%), Postives = 94/179 (52.51%), Query Frame = 1
Query: 2200 YLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFR-----RYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRS 2721
YL + R+ K+++ I+IQK+ R +L R ++ + + A + +Q +FR R + LK + +I+Q RGYL R+ Y+ IR +T IQ + +G+LAR+++ KL +Q AVI+Q + R+ + RR + N+R+ V+ IQ ++KLE + R
Sbjct: 747 YLEKLRLDKLRQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKL---------------------LQEHKAVILQKYARAWLARRRFQNIRRFVLNIQLTYRVQRLQKKLEDQNRE 904 HSP 3 Score: 69.3218 bits (168), Expect = 7.073e-11 Identity = 52/171 (30.41%), Postives = 87/171 (50.88%), Query Frame = 1
Query: 4921 RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRL--KMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFR--RFSELKTFQNLKNASII 5421
R I+IQK+VRG+L R K+ R+ AA+ +QR+FR +R+ I A L + + + +Q Y + YL+R Y IR TI IQ R +++R R+ +L + +I+QK R + R++ ++ V+NIQ +R R + QN +N ++
Sbjct: 757 RQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRK------------------AITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVILQKYARAWLARRRFQNIRRFVLNIQLTYRVQRLQKKLEDQNRENHGLV 909 HSP 4 Score: 65.4698 bits (158), Expect = 1.277e-9 Identity = 52/149 (34.90%), Postives = 79/149 (53.02%), Query Frame = 1
Query: 3001 ILIQTKVRALIQRRKFQYLRNAAIIIQKTFRC-YSVRKKF----LIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKY--LLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQ 3426
I+IQ VR +QRRKF R AA+ IQ+ FR +VRK L + ++AI++QK R + + Y I+ + + IQ HT+GFL + R+Y LLQ+ +I+QK+ RA AR++F N R+F + +Q
Sbjct: 761 IMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLAR-----------------RRYRKLLQEH------KAVILQKYARAWLARRRFQNIRRFVLNIQ 886 HSP 5 Score: 60.8474 bits (146), Expect = 3.147e-8 Identity = 42/130 (32.31%), Postives = 69/130 (53.08%), Query Frame = 1
Query: 2404 GYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTI-----QIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRS--CIIIQKYIRGFINRRNF 2772
YL + ++R+ +IQK+V+G+L R+KF++ +A + IQ FRG R + AA+I+Q + R + R Y +R + I IQ L +R+ K L+ +I+QKY R ++ RR F
Sbjct: 746 AYLEKLRLDKLRQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVILQKYARAWLARRRF 875 HSP 6 Score: 60.8474 bits (146), Expect = 3.200e-8 Identity = 45/130 (34.62%), Postives = 73/130 (56.15%), Query Frame = 1
Query: 4681 GYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKF-----LKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLA---AIILQRHFRKYLIIRR 5046
YL + + R I++Q ++G++ R+ + + R +++ +Q+ FRG +K LK A+I +QK R Y LY+ R A+I IQ + RGFL R +Y R+LL A+ILQ++ R +L RR
Sbjct: 746 AYLEKLRLDKLRQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRY-RKLLQEHKAVILQKYARAWLARRR 874 HSP 7 Score: 59.3066 bits (142), Expect = 7.869e-8 Identity = 49/150 (32.67%), Postives = 81/150 (54.00%), Query Frame = 1
Query: 4522 LIQKIARGYLVRKRIVVEQKAVRIIQNFYRAH-TIRSHFIC----QKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKL--RSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVR-RYCQMKLYRDTRNASIVIQK 4947
+IQK RG+L R++ + E++A IQ ++R T+R + AAI LQK RGYL+R + R I +Q+ +GF+AR+ Y+KL ++I+QK R + A ++F ++ + IQ R + Q KL R +++K
Sbjct: 762 MIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVILQKYARAWLARRRFQNIRRFVLNIQLTYRVQRLQKKLEDQNRENHGLVEK 911 HSP 8 Score: 56.225 bits (134), Expect = 7.494e-7 Identity = 38/123 (30.89%), Postives = 71/123 (57.72%), Query Frame = 1
Query: 3466 KLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQ-----AATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQK---EMKLVILLQSKIRMIITKKRYQ 3810
KL+ I IQK++R LQRR++++ ++A + IQR FR + ++ I AA ++QKY + Y+ + ++ ++ + IQ + R + R++++K E K VI LQ R + ++R+Q
Sbjct: 755 KLRQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVI-LQKYARAWLARRRFQ 876 HSP 9 Score: 56.225 bits (134), Expect = 8.083e-7 Identity = 38/130 (29.23%), Postives = 69/130 (53.08%), Query Frame = 1
Query: 5788 FIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRG-----KLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKL--KNASIIISKHVRGVLVRNHFQ 6156
++ + R +++ + I+IQK R +L +R + R + +Q RG K K A I++QK +GY +R Y++++ + I +Q RGFL R+ + KL ++ ++I+ K+ R L R FQ
Sbjct: 747 YLEKLRLDKLRQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVILQKYARAWLARRRFQ 876 HSP 10 Score: 55.8398 bits (133), Expect = 1.058e-6 Identity = 48/154 (31.17%), Postives = 87/154 (56.49%), Query Frame = 1
Query: 2686 LFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMG--YLRR---KQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEF--VAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQ 3126
L K +L+K + CI+IQK++RG++ RR FL+ + A ++ YF G +R+ LK + I+LQK R +RN + + + + I IQ + + A++ + + ++ +++Q RA + RR+FQ +R + IQ T+R ++KK Q
Sbjct: 748 LEKLRLDKLRQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVILQKYARAWLARRRFQNIRRFVLNIQLTYRVQRLQKKLEDQ 901 HSP 11 Score: 55.8398 bits (133), Expect = 1.103e-6 Identity = 54/179 (30.17%), Postives = 87/179 (48.60%), Query Frame = 1
Query: 3835 ISKFVKGYFARKKYLSYRHSVIVIQNSFRCF-MYRKMFLSIK----FSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLV----RKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFR----KHYIRQQYNETRKKVIFIQSL----IRQFIAIQKYK-QMKKAATY 4317
I K V+G+ R+K+L R + + IQ FR RK + ++AI++QKY RG++ R +Y A IQ + RGFL RK L H A ++Q + R++ R+ F R + IQ +R + + Q E V + SL + +QK + +++KAAT+
Sbjct: 763 IQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEH--KAVILQKYARAWLARRRFQNIRRFVLNIQLTYRVQRLQKKLEDQNRENHGLVEKLTSLAALRVGDLEKVQKLEAELEKAATH 939 HSP 12 Score: 53.5286 bits (127), Expect = 5.316e-6 Identity = 49/160 (30.63%), Postives = 84/160 (52.50%), Query Frame = 1
Query: 5029 YLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAY-----LIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKY---VKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKK-RKN 5481
YL R+D ++ +IQ RG+ R FL ++ + +TIQ YF+ I L+ I +Q R Y+ RN + ++++ I IQ TRG+ R+Y +++ KAVI +QK R + + FQN++ + IQ +R L+K+ + + R+N
Sbjct: 747 YLEKLRLDKLRQDCIMIQKHVRGWLQRRKFLRERQAALTIQRYFRGQQTVRKAITATALKEAWAAIILQKYCRGYLVRNLYQLIRVATITIQAHTRGFLARRRYRKLLQEHKAVI-LQKYARAWLARRRFQNIRRFVLNIQLTYRVQRLQKKLEDQNREN 905
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. UniProt/SwissProt
Match: sp|Q8CJ27|ASPM_MOUSE (Abnormal spindle-like microcephaly-associated protein homolog OS=Mus musculus OX=10090 GN=Aspm PE=1 SV=2) HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0 Identity = 651/2423 (26.87%), Postives = 1090/2423 (44.99%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTH--LSKTKVEDIN----------------KNMPIYIE------------------ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFENPIXXXXXXXXXXXXV----------------------------WVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLTSA------------------------NLFDKEI-------LLENEKRNFQIFFSKLKQIGGAPIILPKE---NEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMK---------KSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSN----YKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCII-IQKYIR----GFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRK----FQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIK------QSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQK---NIRALL-QRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFK---------------------------SYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKK----YLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRK---------------------------IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYI----RQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIR----GYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDT---RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFR------KYLIIRRIDL------------EQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYI----SRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCY---------ILRKE-------------------FKKKRKNCVKI-----QSYIRR----YICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVR------------------TRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLS---IIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRK------------IFLKLKNASIIISKHVRGVLVRNHFQKNKQHMK--IFAQENLRKRLEASIKIQAYFR----------CYIQKRRYCLLKSYTLLIQQRWRFIVLKRS------AVVIQRIWRGRQLRCHLNAKKIGH-EISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK-----AGVLNFDVIGSEFIKLVKNLLYRNINSKR-GTKGITIFCHTCLLLVLLIKMEQ 6867
D+ W ++QE F WLN I KT V +N P E A L SE V AI+K+ E+ L KD +K + + +++YN WL + ++ F + L N++ FI ++LWN DIA ++R + + +L++ L++ L ++ LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + S L VSH+QT +DE+DF V+NL+ D+ GVRL R ++L N ++ KLR PA+ +K N++L ++ K G + G I + HREKTL LLW + +D ++ D+L EI ++ S+ S WV +VC YN V N + + DGR C LIH+Y P Y+ + I T+ + A D E LLENEK+NF + S + +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ K H K ++QS+V FL ++ + ++ Q +R A+ ++ +K KSA+LIQ +RRY R R+ ++K +V+LQS R + +Y + + + IQ + R YL R +++++ S+ +IQ + + R+K TKA V +Q AFR + R+ I+ ++AV+IQS+YR + Y+ +R VI+IQ+ V + +KL KR + I+ +QK+ R G + ++L+ ++A L+ F G R + + +LQ RM R FL +K I +Q ++Y +++ K A I IQT RA I R+ +Q R++ I++Q R RK F S I IQ R+ IC+K + K QS++ +++ K +L ++ I R Q L + +K+Y++VR+S I +Q HFR RKQ K I +Q Y +M RQ++LK+ + IQ RA + QR+ +++ K+A I +Q +R CK ++QI + AA +Q+ F+ +Y + QF K +E+V +Q R R+Q +++ + + +QS RM + +++Y+ AA I + V+ A K+ Y+ RH+ +V Q +++ M R+ A +IQ Y R I+R+ +Y A+ +Q RG VRK + H++A IQ +R+Y+ +K + R +AIVIQ+ +R I Q+Y R+ + +Q+ R ++ + M AAT I+ + K R +Y+ R +A+IIQ R Y Y+ + + Y R L A +Q RG VR+ + A +IQ+ +R H +++F + AA +Q+ R G + ++ R ++L+Q+ +G R+ + + ++ ++Q+ FR F +KFL L+ +I IQ+ R K R A I IQ RG++ R + Q+ AA ++Q FR +Y ++R + ++ AA I+Q RG R+H +S IQ+ F+A+++R++++ +R+ IF+Q R + ++FL+L+ + I IQ R +K + +A IQ FR F K ASI IQ+ +R Y ++R+E F ++R+ K+ ++ RR Y+C K T ++Q H +G+ + ++ + QK+ RA R ++L+ ++ IQ++YR +K Y + +++ +I+ +AR+RFL++++ IIIQ+ +R L+ R + NL +Q+ RG A+ + + R+A ++IQ+ V+ K +I L+KS + +Q +RG+L+RK F + K R + + K+HM IF Q RKRL+ I+ Y + C++Q+ R + +++ + RF++ +R A IQ +WRG R KK H EI IR + + N + ++AL L LT ++ +L L LE VT LS C+ + ES A + ++ CNR V +EVV + V N+ K A V + ++L++ +YR R K +IF TC LL +L+K EQ
Sbjct: 660 DERWKEKQEQGFTWWLNYILTPDDFTVKTNVSKVNAASLVLGAESQHKISVPKAPTKEEVSLRAYTASCRLNRLRRTACSLFTSEKMVKAIKKVEIEIEVGRLLVRKDRHLWKDIGQRQKVLNWLLSYNPLWL----RIGLETVFGELIPLADNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPLLFRDGHEAALSKFTLKKLLLLICFLDHAKISRLIDHDPCLFCKDAEFKASKELLLAFSRDFLSGEGDLSRHLSFLGLPVSHVQTPLDEFDFAVTNLAVDLQCGVRLVRTVELLTQNWNLSDKLRIPAISRVQKMHNVDLVLQVLKSRGVPLTDEHGSAISSKDVVDRHREKTLGLLWKIALAFQVDISLNLDQLKEEIDFLKHTHSIKRAMSALTCPSQAITNKQRDKRISGNFERYGDSVQLLMDWVNAVCAFYNKKVENFTVSFSDGRILCYLIHHYHPCYVPFDAICQRTSQSVACAQTGSVVLNSSSESEGGCLDLSLEALDHESTPEMYKELLENEKKNFHLVRSAARDLGGIPAMIHHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKRDLK-HHQERDKAARVIQSVVLNFLSRRRLQKNVSAALVIQKCWRRVSAQRKLRMLKNEKLAKLQNKSAVLIQAYWRRYSTRKRFLRLKHYSVILQSRIRMKIALTSYKRYLWATVTIQRHWRAYLSRKRDQQIFRKLKSSSLVIQFMFRRW-KRRKLQLQTKAAVTLQRAFREWHLRKQ--IRERSAVVIQSWYRMHRELQKYIYIRSCVIVIQRRV-RCFQAQKLYKRRKDAILTLQKHYRARQKGKLAHADYLQKRAATIRLQAAFRGMKARHSYRLQIGAACVLQSYWRMRQERVRFLNLKKMVIKLQAHIRKYQQLQKYKKIKKAAITIQTHFRASISARRVLASYQKTRSSVIVLQSACRGMQARKAFRHALASVIKIQSYYRAYICRKTFQNFKNATIKLQSIVKMKQSRKQYLQIRAAALFIQRWYRSQKLASQK--RKEYIQVRESCIKLQSHFRGCLVRKQLRLQCKAAISLQSYFRMRTARQRYLKMCKAALVIQSFYCAYRAQISQRKNFLQVKRAAICLQAAYRGCKVRRQIKQQSTAAVTIQRVFRGHSQRMKYQTMLQSAVKIQRWYRAQKVAYDMRIQFLKTREAVVCLQSAYRGWQVRQQLRRQHEAAVKIQSTFRMAVAQQQYKLLRAAAAVIQQHVRARAAGKRQHLAYIQLRHAALVFQAAWKGKMLRRQIARQHQCAALIQSYYRMHIQRRKWSIMKTAALQIQLCYRAYKVGKEQRHLYLKTKAAVVTLQSAYRGMKVRKRVAECHKAAVTIQSKFRAYRTQKKYTTYRTSAIVIQRWYRNIKITTQQHQEYLNLRRAAVQVQAAYRGIRVRRRIQHMHMAATLIEAMFKMRQSRVRYLKMRTAALIIQVRYRAY------------------YLGK-IQHEKYLRTLKAIKTLQAGVRGARVRRTVRKMHFAATLIQSHFRGHRQQTYFHRLRKAATMVQQRYRAVKEGSAEFQRYSRLRRSVLLIQAAFRGLRTRRHLKAMHLAATLIQRRFRTFAMRRKFLSLRKTAIWIQRQYRARLYAKYSRQQLLLEKAVIKIQSSYRGWVVRKRVQKMHRAATVIQATFRMHGAYMRYQHLKRASVVIQVHTAAELQRQKHAAVILQAAVRGMKTRSHLKTMHSSATLIQSQFRAFIVRRRFIALRKAAIFVQRKFRATLYAKHKLHQFLQLRKAAITIQSSYRRLMVQKKLQEMHRAAALIQATFRMHRTYVAFHIWKCASIRIQQCYRTYRTIKLQKEKLIREEQHSAAVLIQSTYRMYRQRCFYQQRRWAAKVIQKTYRANKRRQDLLYVC-------KEETPLLQMHFQGLNTAKQGRQQHGAAMITQKHFRAFKARRLMEAERGFQAGCRKYKAKKYLSKVEAACRIQAWYRRWRAHKKYLTLLKAVNIIEGYLSAQLARRRFLKMRAAAIIIQRKWRATLSVRGARENLKRHRAACVIQAHFRGYQARQSFLQQRSAVLIIQRHVRAMVAAKQERIKYIKLKKSTVVVQALVRGWLVRKRVSEQKAKTRLFHFTAAAYCHMCALKIQRAYRLHVTLRNAKKHMDSVIFIQRWFRKRLQRKRFIEQYHKILSTRREAHACWLQQDR-----AASVIQKAVRRFLLCRRQEKITSCATRIQALWRGYSWR-----KKNDHTEIKAIRRSLRAVSTTVEEENKLYRRTERALHHL----LTYKHLSAILDALKHLEVVTRLSPLCCENMAESGAVSTIFVVIRSCNRSVPCMEVVGYAVQVLLNVAKYDKTIAAVYEAENCVDTLLELLQ--VYREKPGDRVAEKSASIFTRTCCLLAVLLKTEQ 3029
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. UniProt/SwissProt
Match: sp|P62291|ASPM_MACFA (Abnormal spindle-like microcephaly-associated protein homolog OS=Macaca fascicularis OX=9541 GN=ASPM PE=2 SV=1) HSP 1 Score: 574.318 bits (1479), Expect = 1.074e-164 Identity = 599/2180 (27.48%), Postives = 1017/2180 (46.65%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTH--LSKTKVEDIN----------------KNMPIYIE------------------ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFN------VSIDPDFNVSLLSNNEACFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLF----------------------------ENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT------------------------SANLFDKE-------ILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHY---KEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISK---------MKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSN----YKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQK----VVHKVLFKRKLEKRLRSCIIIQK----YIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRK----FQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVR--KYLLQK--QYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRA----LLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSY---------------------------ICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFA----RKKYLSYRHSV-----------------------IVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGF-IKRK---IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFR----KHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQY----LXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRS----HFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF---NAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHF---RKYLIIRRIDLEQ-KAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISR----NRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRY----ICISKFKMIKSATLIIQKHIRGIFVRLKYK---------KIIKLVVFIQKNIRANIVRTRFL---NIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFL----IRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVL-----------KRSAVVIQRIWR 6360
D+ W ++QE F WLN I KT + ++N P E A +L SE V AI+K+ E+ L KD +K + + +++YN WL + +S++ + +V+ L+ FI ++LWN DIA ++R + + +L++ L++ L ++ LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + L V+H+QT DE+DF ++NL+ D+ GVRL R ++L N ++ KLR PA+ +K N+++ ++ K G + G I I HREKTL LLW + +D ++ D+L EI ++ + +LL+ WV +VC YN V N + + DGR C LIH+Y P Y+ + I TT T S FD E LLENEK+NFQ+ S ++ +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ KT H K I+QS V FL ++ + +I Q +R LA+ ++ K+A LIQ +RRY R R+ K+K +++LQS R + +Y + + + IQ + R YL R Y+ ++ S+ IIQ + + R+K KA V++Q AFR + R+ + +A++IQS+YR R Y+ +R VI+IQK + L+KRK E S + IQK Y++G I R N+L+ ++A L+ F L+ + + ++Q RM R FL +K+ I +Q +++ +++ K A ++IQT RA I RK +Q R+A I++Q +R RK ++ S I IQ R+ + +K +L +K + + +Q K +K Y + + Q R K QK +Y+++R+S I +Q R RKQ RK I +Q Y +M + RQ +LK+ +I IQ A + QR+ +++ KKA +Q +R K ++ I + AA +Q F+ Y + +F K K +V +Q R RKQ ++E + + +QS RM +K+++ A L I + + + A R +Y+ RH+V I+IQ+ +R + +K + +K +A++IQKY + + I R+ +Y A+ +Q RG VRK + +++A IQ YR+YK +K + R +AI+IQ+ +R H Q+Y +K I IQS+ R + + M +AAT+I+ + K + R Y T R++A++IQ R Y + R+ + ++ I+Q R +R ++ +AATLIQ R Y + +K + IQ YRA R+ + +++ I +Q RG R++ L+Q + + R+ + L+ +++ +Q+ +R H +FL+++NA I IQ + RR+ K R+ A+ IQ R ++YQ A++++Q+ + R + R+ L Q ++A I+Q +RG R H +S IQ+ F++ L+R++++ +++ TIF+Q R I ++FL+L+ + I IQ R +K + ++A + IQ FR TFQ K ASI+IQ+++R Y R ++ ++YIR++ + + +K +K+ + +KH I ++ Y+ K+ IQ+ RAN + + L +KK SF M+ + K Q Q+ +IQK+C+ F RK +L +++ ++ IQ+ +R+ A R+ +I +QS RG + Q M A LIQ + + + Y+ + +++ +Q + R ++ RK FL ++ + I RG+ VR Q +KI ++E + A+I Q+ CY K +Y ++S ++IQ+ ++ L R+AV IQ +R
Sbjct: 692 DERWKEKQEQGFTWWLNFILTPDDFTVKTNISEVNAATLLLGVENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVKAIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETIYGELISLEDNSDVTGLA-------MFILNRLLWNPDIAAEYRHPTVPHLYRDGHEGALSKFTLKKLLLLICFLDYAKISXLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAITNLAVDLQCGVRLVRTMELLTQNWNLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSCHSDALINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPCYVPXDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSELYKELLENEKKNFQLIRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYK----LKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKW-KRRKMQSQVKATVILQRAFREWHLRKR-AKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKE----SILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRR-LKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHIRKHQQVQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMCKAIIVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQXKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHXXHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTILKAVKILQASFRGVXVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKKMREMHRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLQLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTY---------RAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQ-KQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRT-----QAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLPVQKSVRTIQAAFRGMKVR-------QKLKIVSEEKM-----AAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFR 2826 HSP 2 Score: 370.933 bits (951), Expect = 1.664e-101 Identity = 461/1893 (24.35%), Postives = 848/1893 (44.80%), Query Frame = 1
Query: 2101 VIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRR---------------------------YLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLC----RSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRS----SVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYF----MGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRS------CKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMI----ITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCS----QTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQF---------RKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGY----LIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVR----------------RYCQMKLYRDT---------RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIR----------------RIDLE--QKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYL----IRKKYLEIRQKTIFIQCLVRRYISRNRF---LRLKMSVIIIQKVTRGYFTHRKYV---------------------------KQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL-----VVFIQKNIRANIVRTRFLNIKKSIINIQS----------------------FYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSII------IFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY---------------CLLKS--YTLLIQQRWRFIVLKR------SAVV-IQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK-----AGVLNFDVIGSEFIKLVKNLLYRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSISNSQYSISKDSNIKDSV-SKYRQQLSSRCENIVGSISNSDKILEQMRLNPSWDLKRRFRPNSNSKKTLSTKLGSTNSLQENNLS 7125
VI +QS R ++ K+F S+K I QS+VK R + ++ +A+ IQ+ YR YL R + + A + LQS+FR ++ YLK+ ++I++IQN Y R N+ R++K+ +Q +GY R+ + + A + IQSAFRGY KR Y +++ + IQ +YR+ R +L + +V+ +Q ++++ + ++ + IQ R ++ F FK+A +++ F G +R +++++R++V++LQ + +LR ++ + I+IQ+ R +Q++K++ ++ AA++IQK ++ YS+ ++ Q++ YLK K +V+ +Q +G V+K K + QS R Y +K+Y R S IIIQ+ +R I +++LN +K I +Q + + R+ + I+ + R Y +KA I IQ +FR+ +EK IL +A ++Q F+ + RKM+ + T+IQ RR + F K K+ +Q + R + I KRY K + + I +G AR+ + +IQ FR M R+ FLS+K +A+ IQ+ R + K + Q IK IQ + R +++RK + H++AT IQ +R +++ + + A++VIQ+Q+ R+HY+RQ R+ + +Q+ R + K M +AT IQ + ++R+++++ +++ + +Q+ R + K + +FL RK AA IQ R +V+K++ Q+A +IQ +R H F K A+I +Q++ R Y L ++N+ + +++Q+ KG AR+ ++ ++II+Q +R + + + KL+ A+ IQ+ R C ++D A+I+IQK+ + F R Y + +QR +RK +R R D++ +AA +IQ+FYR + + + +K + V IQNY++ Y+ RK +L +++ IQ R R + KM+ I+ Q Y + +Y Q +A + IQ FRR K + K A++ IQ + + R+ F ++++ + +Q Y R + +F + + A +++Q H R F+ K+++ + L V+ IQ + I + +F IK S I IQ+ +YR +K Y + +++ +IQ + R FL ++++ IIIQ+ +R L+ + + +I +Q+ RG + + + ++A ++IQK ++ K +I +KS + LQ +RG+L+RK L+ K ++ N + + + A +N K++ + I IQ +FR +Q++++ CL + +IQ+ R VL++ S ++ IQ +WRG R + KI IR NR + N + AL L LT ++ +L L LE VT LS C+ + +S A + L+ CNR V +EV+ + V N+ K + V + + ++L++ +YR +K KG +IF TC LL +L+K +N + S + D + S Y+ L++ + N+++IL + + N S + F P + + + ++L L+ +N+
Sbjct: 1659 VIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMCKAIIVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLILQSMWKGKTLR-----------------------RQLQRQXKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGRE---QHHL----------------YLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHXXHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTIL--KAVKILQASFRGVXVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIK-IQSSYRRWMIRKKMREMHRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQ-----RRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHK-------------LHQFLQL----RK--AAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYVRVKTERKSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVTRK-LETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRA-FLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQKTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQQKKFIQKYSIKKIEHEGQECLSQQNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKI----KAIRLSLQVVNREIREENKLYKRTALALHYL----LTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIFVLIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDTLLELLQ--IYREKPGNKVADKGGSIFTKTCCLLAVLLK-----TTNRASDVRSRSKVVDRIYSLYK--LTAHKHKM-----NTERILHKQKKNSSISIP--FIPXTPVRTRIVSRLKPDWVLRRDNME 3456 HSP 3 Score: 357.451 bits (916), Expect = 2.215e-97 Identity = 398/1566 (25.42%), Postives = 753/1566 (48.08%), Query Frame = 1
Query: 2029 IQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYL----VQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRS----SVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYL----RRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRAL----IQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALL----QRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEM----KLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIR----QQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXX---XXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTI----RSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF--NAHK--KFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQK-------AARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAY--------------LIRKKYLEIRQKTIFIQ--------CLVRRYISRN---RFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKK-----------SIINIQSF--YRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSN---IIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRK--------RLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQ-------QRWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHE 6408
IQ+ ++ Y + +T+++ I +Q+ RR + I+ +I QS + R R +KK+ I +Q + R++ +Y+K+K A V++Q+HFR Y+ V +Y K +++++Q+ RG R Y I S IQ Y + Y+++K+F+ L + +QS + R+ Y AA+ IQ YRS + R Y+ +R+S I +Q V L ++++ + ++ I +Q Y R R+ +LK A+ ++++Y+ Y +RK FL+++ + LQ R +R + +A+ IQ +F+ Y + ++ + + I IQ RA R +F + A + +Q +R + VRK+ ++ +A+ IQ R QK + K + LVIQ++ + + + RK + +Y+++R + +I+Q ++ + R+Q K I++Q Y +MH ++K+ +K + IQK +A Q Y+K K AV+ +Q +R K +K+I N+AA +Q +++Y KK++ + S +IQ++ R + +E K I +QS R I ++ Q A I K + +R Y + R + IVIQ FR Y +G + R+ Y + A+K++Q + RG VR TL +ATLIQ YR YK + F + IQ+++R R ++YN+ R VI+IQ++ R A + K M AAT IQ+ + ++R+++++ +++AV IQ+ R +L K + Q RR+++R + AAT IQ R + V R ++A +IQ Y A+ R H++ Q+ +A+ LQ RG R++ + L+QS + + R+ + L+ ++I VQ+ +R HK +FL+L+ A+I IQ + RR K ++ + A+++IQ R + +Q A+I++Q+H+R Y R L+++ +A +IQ Y+G R H + + + IQ+ ++ Y +I++KY ++K +Q C+ + N + + IIIQK + + + Y+ + V++IQ+ +R+ + ++T A I IQ +R + +R++ + + IQS+ R + ++ K+A ++IQ + R ++VR+K ++ K + +QK++R R + +++ +I+N + YR +Y+ Q + + + + +A + E S + IQ FRR + R + + +Q ++ + + ++ + + A I +Q + + RK + + +K+ + LQ R FL R+++L+++++ III +G + + FQ+ K + I Q R+ +++A+ KIQA++RC+ + Y + +IQ +R F+ ++ SA++IQR WR + + KI HE
Sbjct: 1517 IQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVI-QSYWRMRQDRVRFLNLKKTIIKLQAHIRKHQQVQKYKKMKKAAVIIQTHFRAYIFTRKVLASYQKTRSAVIVLQSAYRGMQARKVYIHILTSVIKIQSYYRAYVSKKEFLSLKNTTIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKITTQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMCKAIIVIQNYYHAYKAQVNQRKNFLRVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAW-----------------TAGRKQRM--EYIELRHAVLILQSMWKGKTLRRQLQRQXKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHXXHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRA-------------------YYQGKMHREKYLTILKAVKILQASFRGVXVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKKMREMHRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLQLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTY---RAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRT-----QAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYR-LYVRVKTER--KSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQ--SEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVT-RKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIK-NSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRA------ILSAKIAHE 3022 HSP 4 Score: 305.449 bits (781), Expect = 1.677e-81 Identity = 364/1403 (25.94%), Postives = 648/1403 (46.19%), Query Frame = 1
Query: 2029 IQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLC----RIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGY-LARKK---FVKLTKAIVVIQSAFRG-----------------------YAKRRNYTIQIKAAVIIQSFYR----SSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSC-----------------------IIIQ----KYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKE-------FVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKN---YLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISA----RKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRS--CKEKK--QIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMI----ITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFR-----CFMYRKMFLSIKF--------------------------------------------SAIVIQKYLRGFIKRKIY------------------CSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYI-----RQQYNETRKKVIFIQSLIRQFIAIQKYK---QMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYV----RRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKN----FTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRK----------YLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRK----KYLEIRQKTIFIQCLVRRYISRNRFLRLK---------------MSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTF-------------------QNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYIC-----ISKFKMIKSATLIIQKHIR 5577
IQR +R Y+T + +T F+ V+ +QS R + K+ + + QS + A+ + K +A++IQ+N+R + R+ Y +++ A ++LQS ++ +++ + + +IIQ+ R ++ + +K ++K+ +IQKY K Y + R++ ++K A+V +QSA+RG Y ++ Y +A+IIQ +YR + + YLNL+K+ I IQ V + +R ++ R+ I+IQ Y +G ++R +L AV IL+ F G R KM+ + L+Q N R + F K I + +RY A KE + + + I IQ R RR + + AA +IQ+ FR +R++FL +A+ IQ+ R+ +C K+ +L+++ +V+ IQ + ++++K +++ Q+ R + + +Y +++++++IQ+ + A A R+ +L R+ +++Q + + R+ + S IQ R+LL RRR+I KKA IF+QRK+R+ C + K Q + +AA +Q ++ + KK+ ++M+ + +IQ R FQ + IL+Q R + K+ Y ++ + + I KG AR+ + I+IQ+++R CF Y+K+ + K +AI+IQK+ + F RK Y +T A+ IQ RGF VR+ + + H++ATLIQ FYR ++ + ++ K+ A +VIQ +R Y+ R+ + +K V IQ+ R QK K + K AA Q Y + +Y + V+IQ+ + S + + S + RR + R + +K AA IQ + + R+R V +++A +Q+++R R F+ + AA+ LQ + R +L K+ + + R+ +I++Q+ KGFI ++ +Q++++S+I +Q ++R + A K K+K A+ IQ R + K Y A +IQ L R + +AII+QR +R +L+I+R +AA +IQ YRGY R FL QK++ + IQ Y +A K KY+E ++ T+ +Q LVR ++ R R L K ++ + IQ+ + Y + KQ +VI IQ+ FR + K F QN A+ +IQK R ++LRK+ +K +KIQ+ R Y +K K I+ + ++ + IR
Sbjct: 1854 IQRWYRAYKTLHDTRTRFLKTKAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQXKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHXXHQEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMHREKYLTILKAVKILQASFRGVXVRWTLRKMQIAATLIQSNYRRYKQQTYF---NKLKKITKTIQQRYRAVKERNIQFKRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKKMREMHRAATFIQATFRMHRVHMRYQALKQASVVIQQQYXANRAAKLQRQHYLRQRRSAVILQAAFRGVKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLQLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTCVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQTAYKGMKARQHLREKHKAAIIIQSTYRMYRQYCF-YQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNIQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRL-YVRVKTERKSFLPVQKSVRTIQAAFRGMKVRQKLKIVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASDLACSQEAECHSQSRAAVTIQNAFRRMVTRKLETQK-CAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVK-AACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKR----HRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQKTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQQKKFIQKYSIKKIEHEGQECLSQQN--RAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVNREIR 3243
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. UniProt/SwissProt
Match: sp|P62289|ASPM_GORGO (Abnormal spindle-like microcephaly-associated protein homolog OS=Gorilla gorilla gorilla OX=9595 GN=ASPM PE=2 SV=1) HSP 1 Score: 571.622 bits (1472), Expect = 8.829e-164 Identity = 598/2169 (27.57%), Postives = 1012/2169 (46.66%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTH--LSKTKVEDIN----------------KNMPIYIE------------------ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLF----------------------------ENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT------------------------SANLFDKE-------ILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISK---------MKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSN----YKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQK----VVHKVLFKRKLEKRLRSCIIIQK----YIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRK----FQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVR--KYLLQK--QYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRA----LLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSY---------------------------ICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFA----RKKYLSYRHSV-----------------------IVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGF-IKRK---IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRK----HYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYV----RRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRS----HFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF---NAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHF---RKYLIIRRIDLEQK-AARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISR----NRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRY----ICISKFKMIKSATLIIQKHIRGIFVRLKYK---------KIIKLVVFIQKNIRANIVRTRFL---NIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFL----IRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVL-----------KRSAVVIQR 6351
D+ W ++QE F WLN I KT + ++N P E A +L SE V AI+K+ E+ L KD +K + + +++YN WL + + +SL N++ FI ++LWN DIA ++R + + +L++ L++ L +V LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + L V+H+QT DE+DF V+NL+ D+ GVRL R ++L N D+ KLR PA+ +K N+++ ++ K G + G I I HREKTL LLW + +D ++ D+L EI ++ + +LL+ WV +VC YN V N + + DGR C LIH+Y P Y+ + I TT T S FD E LLENEK+NF + S ++ +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ K H K I+Q V FL ++ + ++ Q +R LA+ ++ K+A LIQ +RRY R R+ K+K +++LQS R + +Y + + + IQ + R YL R Y+ ++ ST +IQ + + R K KA V++Q AFR + R+ + + +A+IIQS+YR + Y+ +R V+IIQK + L+KRK E S + IQK Y++G I R N+L+ ++A L+ F L+ + + ++Q RM R FL +K+ I +Q +++ ++++ K A ++IQT RA I RK +Q R+A I++Q +R RK ++ S I IQ R+ + +K +L +K + + +Q K +K Y + + Q R K QK +Y+++R+S I +Q R RKQ RK I +Q Y +M + RQ +LK+ +I IQ A + QR+ +++ KKA +Q +R K ++ I + AA +Q F+ Y + F K K ++ +Q R RKQ ++E + V+ +QS RM +K+++ A L I + K + A R +Y+ RH+V ++IQ+ +R + +K + +K +A++IQKY R + I R+ +Y A+ +Q RG VRK + +++A IQ YR+YK +K + R +AI+IQ+ +R ++ ++Y +K I IQS+ R + + M +AAT+I+ + K + R Y T R++A++IQ R Y K+ + K +I+ K + R +R ++ +AATLIQ R Y + +K + +Q YRA R+ + +++ I +Q RG R++ L+Q + + R+ + L+ ++I++Q+ +R H +FL+++NA I IQ + RR+ K R+ A+ IQ R ++YQ A++++Q+ + R + R+ L Q+ +A I+Q +RG R H +S IQ+ F++ L+R++++ +++ TIF+Q R I ++FL L+ + I IQ R +K + ++A I IQ FR TFQ K+ASI+IQ+++R Y + K +R+N YIR++ + + +K +K+ L+ +KH I ++ Y+ K+ IQ+ RAN + + +KK F M+ + K Q Q+ +IQK+C+ F RK +L +++ ++ IQ+ +R+ A R+ +I +QS RG + Q M A LIQ + + + Y+ + +++ +Q + R ++ RK FL ++ + I RG+ VR Q +K ++E + A+I Q+ CY K +Y ++S ++IQ+ ++ L R+AV IQ+
Sbjct: 691 DERWKEKQEQGFTWWLNFILTPDDFTVKTNISEVNAATLLLGIENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVKAIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGEL--ISLEDNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYAKISRLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDVVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRH-QEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRRRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLVIQSMFRKWKQR-KMQSQVKATVILQRAFREWHLRK-HAKEENSAIIIQSWYRMHKELQKYIYIRSCVVIIQKRFRCFQAQKLYKRKKE----SILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRR-LKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYVHILTSVIKIQSYYRAHVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAALISLQSAYRGWKVRKQIRREHQAVLKIQSAFRMAKAQKQFRLFKTAALVIQQNFKAWTAGRKQRMEYIELRHAVLMLQSMWRGKTLRRQLQRQHKCAVIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAVFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKTQREKYLTILKAVKILQASFRGVRVRRTLRKMQIAATLIQSNYRRYRKQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTY---RAAKLQREN------YIRQWHSAVVIQAAYKGMKARHLLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIK-KQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRT-----QAVICIQSYYRGFKVRKDIQNMHQAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMEVR-------QKLKNVSEEKV-----AAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQK 2822 HSP 2 Score: 378.637 bits (971), Expect = 7.982e-104 Identity = 498/1949 (25.55%), Postives = 887/1949 (45.51%), Query Frame = 1
Query: 2014 RAASCIQRVWR----KYRTFYLYKT------HFIAHY---------KEVIIVQSIVRRFL----CLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIR----GYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVV--HKV--LFKR-------------------KLEKRLRSCIIIQKYIRGF----INRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKK----EFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVR--SIICQKN--YLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSC------KEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMI----ITKKRYQKKIAATLTISKFVKGYFARKKYLSYRH-SVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCS----QTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQF---------RKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGY----LIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVR----------------RYCQMKLYRDT---------RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIR----------------RIDLE--QKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYL----IRKKYL----------------EIRQK----------TIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYF----THRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL-----VVFIQKNIRANIVRTRFLNIKKSIINIQS----------------------FYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSII------IFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY----------------CLLKS--YTLLIQQRWRFIVLKR------SAVV-IQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSE-FIKLVKNLL--YRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSISNSQYSISKDSNIKDSV-SKYRQQLSSRCENIVGSISNSDKILEQMRLNPSWDLKRRFRPNSNSKKTLSTKLGSTNSLQENNLS 7125
RAA IQ WR + R L KT H H K +I+Q+ R ++ L ++ + +I+ QS + AR + S I IQ YR ++ + + +K+AT+ LQS + +K YL + + L IQ R R Y ++R+S +Q +V+GYL RK+ KA++ +QS FR R+ Y KA ++IQ++Y + R+ +L ++K+ +Q +KV L K+ K + L+S I IQ++ R + R +FLK K+A+ L+ + G+ RKQ + +V+ +Q RM + F + + +A++IQ++FK + A + E++ + A +++Q+ R RR+ Q A+IIQ +R + +KK+ I +A++IQK R SI ++N YLK K +V+ +Q +G V+K K + QS R Y +K+Y R S IIIQ+ +R I K++LN +K I +Q + + R+ + I+ + R Y +KA I IQ +FR+ +EK IL +A ++Q F+ ++ RKM+ + T+IQ RR + F K K+ +Q + R + I +RY K + + I +G AR+ +L H + +IQ FR M R+ FLS+K +AI+IQ+ R + K + Q IK IQ + R +++RK + H++AT IQ +R +++ + + A++VIQ+Q+ R+HY+RQ R + +Q+ R + K M +AT IQ + ++R+++++ +++ + +Q+ R + + L + ++ RK AA IQ R +V+K++ Q+A +IQ +R H + F K+A+I +Q++ R Y L R+N+ + +++Q+ KG AR ++ +SII+Q +R + + + KL+ A+ IQ+ R C ++D A+I+IQK+ + F R Y + +QR +RK +R R D++ +AA +IQ+FYR + + + +K + V IQNY++ Y+ RK +L E+RQK I Q + Y S+ ++ ++ ++IQ+ + +Y Q +A + IQK F R + K + K A++ IQ + + R+ F ++++ + +Q Y R + +F + + A +++Q H R F+ K+++ + L V+ IQ + I + +F IK S I IQ+ +YR +K Y + +++ +IQ + R RFL ++++ IIIQ+ +R L+ + + +I +Q+ RG + + + ++A ++IQK ++ K +I +KS + LQ +RG+L+RK L+ + ++ N + + + A ++ K++ + I IQ +FR +Q++R+ CL + +IQ+ R +L++ S ++ IQ +WRG R + KI IR NR + N + AL L LT ++ +L L LE VT LS C+ + S A + L+ CNR V +EV+ + V N+ K V E I ++ LL YR +K KG +IF TC LL +L+K +N + S + D + S Y+ L++ + N+++IL + + N S + F P + + + ++L L+ +N+
Sbjct: 1560 RAACVIQSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYVHILTSVIKIQSYYRAHVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAALISLQSAYRGWKVRKQIRREHQAVLKIQSAFRMAKAQKQFRLFKTAALVIQQNFKAWTAGRKQRMEYIELRHAVLMLQSMWRGKTLRRQLQRQHKCAVIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAVFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKTQREKYLTIL--KAVKILQASFRGVRVRRTLRKMQIAATLIQSNYRRYRKQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARR-HLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIK-IQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQ-----RHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----------------AKHKLHQFLHLRK--AAITIQSSYRRLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARHLLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHQAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMEVRQKLKNVSEEKVAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMATRK-LETQKYAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRA-FLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLHFTAAAYYHLNALRIQRAYKLYLAMKHANKQVNSVICIQRWFRARLQEKRFIQKYHSVKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKI----KAIRLSLQVVNREIREENKLYKRTALALHYL----LTYKHLSAILEALKHLEVVTRLSPLCCENMAHSGAISKIFVLIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLK-----TTNRASDVRSRSKVVDRIYSLYK--LTAHKHKM-----NTERILYKQKKNSSISIP--FIPETPVRTRIVSRLKPDWVLRRDNME 3456 HSP 3 Score: 365.925 bits (938), Expect = 5.293e-100 Identity = 407/1565 (26.01%), Postives = 758/1565 (48.43%), Query Frame = 1
Query: 2029 IQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYL----VQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRS----SVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYL----RRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRAL----IQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALL----QRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEM----KLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIR----QQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXX---XXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTI----RSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF--NAHK--KFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQK-------AARIIQNFYRGYTIRAHFLCQKN-SCVTIQNYFKAY--------------LIRKKYLEIRQKTIFIQ--------CLVRRYISRN---RFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKK-----IIKLVVFIQKNIRANIVRTRFLNIKK----SIINIQSF--YRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSN---IIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRK--------RLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQ-------QRWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHE 6408
IQ+ ++ Y + +T+++ I +Q+ RR + I+ +I QS + R R +KK+ I +Q + R++ R +Y+K+K A V++Q+HFR Y+ V +Y K +++++Q+ RG R Y I S IQ Y + ++++K+F+ L A + +QS + R+ Y AA+ IQ YRS + R Y+ +R+S I +Q V L ++++ + ++ I +Q Y R R+ +LK A+ ++++Y+ Y +RK FL+++ + LQ R +R + +A+ IQ +F+ Y + ++ + + I IQ RA R F + A I +Q +R + VRK+ ++ + + IQ R QK + K + LVIQ++ K + + RK + +Y+++R + +++Q +R + R+Q K +++Q Y +MH ++K+ +K + IQK RA Q Y+K K AV+ +Q +R K +K+I N+AA +Q +++Y KK++ + S +IQ++ R + KE K I +QS R I ++ Q A I K + +R Y + R + IVIQ FR Y +G +R+ Y + A+K++Q + RG VR+TL +ATLIQ YR Y+ + F + +Q+++R R Q+YN+ R VI+IQ++ R A + K M AAT IQ+ + ++R+++++ +++A++IQ+ R +L K + Q RR+++R + AAT IQ R + + R ++A +IQ Y+A+ R H++ Q+++A+ LQ RG R++ + L+QS + + R+ + L+ ++I VQ+ +R HK +FL L+ A+I IQ + RR K ++ + A+I+IQ R +Q A+I++Q+H+R Y R L+++ +A +IQ Y+G R H L +K+ + + IQ+ ++ Y +I++KY ++K Q C+ + N + + IIIQK + + + Y+ + V++IQ+ +R+ + ++T A I IQ +R + +RK+ + + IQS+ R + ++ K+A ++IQ + R ++VR+K ++ + K V IQ R VR + N+ + +I+N + YR +Y+ Q + + + + +A + E S + IQK F R +A R + + +Q ++ + + ++ + + A I +Q + + RK + + +K+ + LQ R FL R+++L+++++ III +G + + FQ+ K + I Q R+ +++A+ KIQA++RC+ + Y + +IQ +R RF+ ++ SA++IQR WR + + KI HE
Sbjct: 1516 IQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVI-QSYWRMRQDRVRFLNLKKTIIKLQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYVHILTSVIKIQSYYRAHVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAALISLQSAYRGWKVRKQIRREHQAVLKIQSAFRMAKAQKQFRLFKTAALVIQQNFKAW-----------------TAGRKQRM--EYIELRHAVLMLQSMWRGKTLRRQLQRQHKCAVIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAVFKMHQSRISYHTMRKAAIVIQVRFRA-------------------YYQGKTQREKYLTILKAVKILQASFRGVRVRRTLRKMQIAATLIQSNYRRYRKQTYFNKLKKITKTVQQRYRAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQATFRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTY---RAAKLQRENYIRQWHSAVVIQAAYKGMKAR-HLLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRT-----QAVICIQSYYRGFKVRKDIQNMHQAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYR-LYVRVKTERKNFLAVQKSVRTIQAAFRGMEVRQKLKNVSEEKVAAIVNQSALCCYRSKTQYEAVQ--SEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCR-MATRKLETQKYAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIK-NSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRA------ILSAKIAHE 3021 HSP 4 Score: 213.001 bits (541), Expect = 1.946e-53 Identity = 243/991 (24.52%), Postives = 458/991 (46.22%), Query Frame = 1
Query: 1954 FIMATLAFFSSRL-IDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCR----IRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGY----LARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKL--EKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQK----NVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXC---QSLVRKYLLQKQYLKVRKSTIIIQKHFR----AISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQ---VITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFR----KMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKK 4839
FI AT F RL + T +A+ IQ+ ++ R L + H++ +I+Q+ R + KS+ + QS + L R R +KK+ I +Q+ YR +C ++ ++ A + +QS +RR +V+K ++ R+ ++IQ R + + ++ + ++ +IQ++ + Y L R+ +++ + VVIQ+A++G R + KA++IIQS YR Y L+ + IIQ+ K+K L+ +Q + ++ + A I++ + + RK +L +R +V+ +Q+ R L+ + A I IQ+ R R+ Q + AA +IQ +R + + + + + +VIQ VR +KN+L +++SV IQ +G V++ K + + QS + Y + QY V+ ++IQ+ ++ A S ++ + + + +QK CR KL++Q + IQ ++ + RRR+++ K+A I +Q FR+ + +KQ +L +AA V+Q ++++++ K R +++ SV +IQ + I +++FQ+ I +Q+ R KK Y K+ A I + + + A K+YL+ +V +IQ F + R FL+++ SAI+IQ+ R + KI IK H++A LIQ YR YK R+ F+ +++AA++IQK YIR + R+++ KY + KK+ +Q + +G+++RK+ + QR ++ F + Y L A IQ+ + YL K + +V IQ ++RA FI + ++ K++ + L ++N + ++Q ++ F+ RK +K S I +Q ++RG++ KK
Sbjct: 2339 FIQAT--FRMHRLHMRYQTLKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAILIQATFRMHRTYTTFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARHLLREKHKASIIIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKAFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLT----------------------------AVRTQAVICIQSYYRGFKVRKDIQNMHQAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMEVRQKLKNVSEEKVAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAF----CRMATRKLETQKYAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILSAKIAHEHFLMIK-----------------RHRAACLIQAHYRGYKGRQVFLRQKSAALIIQK-----YIRAREAGKRERI--------------KYIEFKKSTVILQALVRGWLVRKRILEQRAKIRLLH----------------------------FTAAAYYH---LNALRIQRAYKLYLAMKHANKQVNSVICIQRWFRARLQEKRFIQKYHSVKKIEHEGQECLSQRNRAAS-----VIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKK 3222
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. UniProt/SwissProt
Match: sp|P62287|ASPM_COLGU (Abnormal spindle-like microcephaly-associated protein homolog OS=Colobus guereza OX=33548 GN=ASPM PE=3 SV=1) HSP 1 Score: 568.926 bits (1465), Expect = 6.755e-163 Identity = 597/2180 (27.39%), Postives = 1012/2180 (46.42%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTH--LSKTKVEDIN----------------KNMPIYIE------------------ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFN------VSIDPDFNVSLLSNNEACFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLF----------------------------ENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT------------------------SANLFDKE-------ILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHY---KEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISK---------MKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSN----YKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQK----VVHKVLFKRKLEKRLRSCIIIQK----YIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRK----FQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVR--KYLLQK--QYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRA----LLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSY---------------------------ICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFA----RKKYLSYRHSV-----------------------IVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGF-IKRK---IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRK----HYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQY----LXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRS----HFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF---NAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHF---RKYLIIRRIDLEQK-AARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISR----NRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRY----ICISKFKMIKSATLIIQKHIRGIFVRLKYK---------KIIKLVVFIQKNIRANIVRTRFL---NIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFL----IRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVL-----------KRSAVVIQRIWR 6360
D+ W ++QE F WLN I KT + ++N P E A +L SE V AI+K+ E+ L KD +K + + +++YN WL + +S++ + +V+ L+ FI ++LWN DIA ++R + + +L++ L++ L +V LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + L V+H+QT DE+DF ++NL+ D+ GVRL R ++L N + KLR PA+ +K N+++ ++ K G + G I I HREKTL LLW + +D ++ D+L EI ++ + +LL+ WV +VC YN V N + + DGR C LIH+Y P Y+ + I TT T S FD E LLENEK+NF + S ++ +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ KT H K I+QS V FL ++ + +I Q +R LA+ ++ K+A LIQ +RRY R R+ K+K +++LQS R + +Y + + + IQ + R YL R Y+ ++ S+ IIQ + + R K KA V++Q AFR + R+ + +A++IQS+YR R Y+ +R VI+IQK + L+KRK E S + IQK Y++G I R N+L+ ++A L+ F L+ + + ++Q RM R FL +K+ I Q +++ +++ K A ++IQT RA I RK +Q R+A I++Q +R RK ++ S I IQ R+ + +K +L +K + + +Q K +K Y + + Q R K QK +Y+++R+S I +Q R RKQ RK I +Q Y +M + RQ +LK+ +I IQ A + QR+++++ KKA +Q +R K ++ I + AA +Q F+ Y + F K K +V +Q R RKQ ++E + + +QS RM +K+++ A L I + + + A R +Y+ RH+V I+IQ+ +R + +K + +K +A++IQKY + + I R+ +Y A+ +Q RG VRK + +++A IQ YR+YK +K + R +AI+IQ+ +R H ++Y +K I IQS+ R + + M +AATYI+ + K + R Y T R++A++IQ R Y + R+ + ++ I+Q R +R ++ +AATLIQ R Y + +K + IQ YRA R+ + +++ I +Q RG R++ L+Q + + R+ + L+ +++ +Q+ +R H +FL+++NA I IQ + RR+ K R+ A+ IQ R ++YQ A++++Q+ + R + R+ L Q+ +A I+Q +RG R H +S IQ+ F++ L+R++++ +++ TIF+Q R I ++FL+L+ + I +Q R +K + ++A + IQ FR TFQ K ASI+IQ+++R Y R ++ ++YIR++ + + +K +K+ + +KH I ++ Y+ K+ IQ+ RAN + + L +KK SF M+ + K Q Q+ +IQK+C+ F RK +L +++ ++ IQ+ +R+ R+ +I +QS RG + Q M A LIQ + + + Y+ + +++ +Q + R ++ RKIFL ++ + I RG+ VR Q +K ++E + A+I Q+ CY K +Y ++S + IQ+ ++ L R+AV IQ+ +R
Sbjct: 692 DERWKEKQEQGFTWWLNFILTPDDFTVKTNISEVNAATLLLGVENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVKAIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETIYGELISLEDNSDVTGLA-------MFILNRLLWNPDIAAEYRHPTVPHLYRDGHEGALSKFTLKKLLLLVCFLDYAKISKLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAITNLAVDLQCGVRLVRTMELLTQNWSLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTQSIKRTISLLSCHSDALINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYK----LKTDLKRHQERDKAARIIQSAVINFLAKQRLRKRVNAALIIQKYWRRVLAQRKLLILKKEKLEKVQNKAASLIQGYWRRYSTRKRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSSLIIQSMFRKWKQR-KMQSQVKATVILQRAFREWHLRKR-AKEENSAIVIQSWYRMHKELRKYIYIRSCVIVIQKRFRCFQAQKLYKRKKE----SILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRR-LKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIATQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQAAYRGYKIRQLIKQQSIAAVKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHRQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATYIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQREKYLTILKAVKILQASFRGVRVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKKMREMHRAATFIQATFRMQRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLHQFLQLRKAAITVQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTYVTFQTWKQASILIQQHYRTY---------RAAKLQKENYIRQWHSAVVIQAAYKGMKARQHLREKHKAAIIIQSTYRMHRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKETCVQASFQDMNMQ-KQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTVVRT-----QAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYIRVKTERKIFLAVQKSVRTIQAAFRGMKVR-------QKLKNISEEKM-----AAIVNQSALCCYRSKTQYEAVQSEGVTIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFR 2826 HSP 2 Score: 374.785 bits (961), Expect = 1.101e-102 Identity = 482/1952 (24.69%), Postives = 883/1952 (45.24%), Query Frame = 1
Query: 2014 RAASCIQRVWR----KYRTFYLYKT--HFIAHY-------------KEVIIVQSIVRRFL----CLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIR----GYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYL----RRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALI----QRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXX----XXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIK----MHQCRQKFLKLKSQVITIQKNIRALLQRRR---------YIKN--------------KKAVIFIQRKFRSC------KEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMI----ITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCS----QTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQF---------RKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGY----LIRKNFTETRNKIILVQSLMKGFIARK----------------------C-YQKLRSSSIIVQKIFRGFNAHKKFL---KLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIR----------------RIDLE--QKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYL----IRKKYLEIRQKTIFIQCLVRRYISRNRFLRL---KMSVIIIQKVTRGYFT---------------------------HRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL-----VVFIQKNIRANIVRTRFLNIKKSII----------------------NIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSII------IFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTL-------------------LIQQRWRFIVLKR------SAVV-IQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK-----AGVLNFDVIGSEFIKLVKNLLYRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSISNSQYSISKDSNIKDSV-SKYRQQLSSRCENIVGSISNSDKILEQMRLNPSWDLKRRFRPNSNSKKTLSTKLGSTNSLQENNLS 7125
RAA IQ WR + R L KT F AH K +I+Q+ R ++ L ++ + +I+ QS + AR + S I IQ YR Y+ + + +K+AT+ LQS + +K YL + + L IQ R R Y ++R+S +Q +V+GYL RK+ KA++ +QS FR R+ Y KA ++IQ++Y + R+ +L ++K+ +Q ++ ++++ + + IQ RG+ R + ++ ++ ++ Y R FLK + +V+ LQ R +R + ++A+ IQ +F+ A+K+F K+A ++IQ RA QR ++ LR+A +I+Q ++ ++R++ Q+ AI+IQ R + QK + +K++ L+IQK+ K + + + ++ QS R ++K+ K+ + IQ +RA +K++ +R I++Q++ + H+ +++L LK I IQ R + RR YIK +KA I IQ +FR+ +EK IL +A ++Q F+ + RKM+ + T+IQ RR + F K K+ +Q + R + I +RY K + + I +G AR+ + +IQ FR M R+ FLS+K +A+ IQ+ R + K + Q IK IQ + R +++RK + H++AT IQ +R ++ + + A++VIQ+Q+ R+HY+RQ R + +Q+ R + K M +AT IQ + ++R+++++ +++ + +Q+ R + K + +FL RK AA +Q R +V+K++ Q+A +IQ +R H F K A+I +Q++ R Y L ++N+ + +++Q+ KG AR+ C YQKL+ ++ I+Q+ +R +K L +LK + C+Q + + K ++ A+I+IQK+ + F R Y + +QR +RK ++R R D++ +AA +IQ+FYR + + + +K + V IQNY++ Y+ RK +L +++ IQ R R + + KM+ I+ Q Y + +Y Q +A + IQK FRR K + K A++ IQ + + R+ F ++++ + +Q Y R + +F + + A +++Q H R F+ K+++ + L V+ IQ + I + +F IK S I IQ++YR +K Y + +++ +IQ + R FL ++++ IIIQ+ +R L+ + + +I +Q+ RG + + + ++A ++IQK ++ K +I +KS + LQ +RG+L+RK L+ + ++ N + + + A +N K++ + I IQ +FR +Q++++ + K Y++ +IQ+ R VL++ S ++ IQ +WRG R + K I IR NR + N + AL L LT ++ +L L LE VT LS C+ + +S A + L+ CNR V +EV+ + V N+ K + V + + ++L++ +YR +K KG +IF TC LL +L+K +N + S + D + S Y+ L++ + N+++IL + + N S + F P + + + ++L L+ +N+
Sbjct: 1561 RAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHIRKHQQLQKYKKMKKAAVIIQTHFRAYIFARKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSIVKMKQTRKQYLHLRAAALFIQQCYRSKKIATQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKKFLRVKKAATCLQAAYRGYKIRQLIKQQSIAAVKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVVSLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQRMEYIELRHAVLILQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYKAYSIGREQHHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITHRQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATYIKAMFKMHQSRISYHTMRKAAIVIQVRFRAYYQGKMQREKYLTIL--KAVKILQASFRGVRVRWTLRKMQIAATLIQSNYRRYKQQTYFNKLKKITKTIQQRYRAVKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHVAATLIQRRFRTLMMRRRFLSLKKTAVWIQRKYRAHLCTKHHLQFLQVQNAVIK-IQSSYRRWMIRKKMREMHRAATFIQATFRMQRVHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQ-----RHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHK-------------LHQFLQL----RK--AAITVQSSYRRLMVKKKLQEMQRAAVLIQATFRMHRTYVTFQTWKQASILIQQHYRTYRAAKLQKENYIRQWHSAVVIQAAYKGMKARQHLREKHKAAIIIQSTYRMHRQYCFYQKLQWATKIIQEKYRANKKKQKALQHNELKKET-CVQASFQDMNMQKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTVVRTQAVICIQSYYRGFKVRRDIQNMHRAATLIQSFYRMHRAKVDYQTKKTAIVVIQNYYRLYIRVKTERKIFLAVQKSVRTIQAAFRGMKVRQKLKNISEEKMAAIVNQSALCCYRSKTQYEAVQSEGVTIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFRRMVTRKV-ETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRA-FLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGGFYTKLERTWFLNVRASAIIIQRKWRAILSAKIAHEHFLMIKRHRAACLIQAHYRGYKERQVFLRQKSAALIIQKYIRAREAGKRERIKYIEFKKSTVILQALVRGWLVRKRILEQRTKIRLLHFTAAAYYHLNALRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQQKKF-IQKYYSIEKIEHEGQECLSQRNRAASVIQKAVRHFVLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTK----IKAIRLSLQVVNREIREENKLYKRTALALHYL----LTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIFVLIRSCNRSVPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCVDTLLELLQ--IYREKPGNKVADKGGSIFTKTCCLLAILLK-----TTNRASDVRSRSKVVDRIYSLYK--LTAHKHKM-----NTERILHKQKKNSSISIP--FIPETPVRTRIVSRLKPDWVLRRDNME 3457
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. UniProt/SwissProt
Match: sp|Q8IZT6|ASPM_HUMAN (Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens OX=9606 GN=ASPM PE=1 SV=2) HSP 1 Score: 568.54 bits (1464), Expect = 8.953e-163 Identity = 594/2185 (27.19%), Postives = 1011/2185 (46.27%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTH--LSKTKVEDIN----------------KNMPIYIE------------------ATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLF----------------------------ENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT------------------------SANLFDKE-------ILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISK---------MKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSN----YKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQK----YIRGFINRRNFLKFKSAVNILEHYF------------------MGYLRRKQ----FLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRY-FAKKEFVA---KKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQK-HTKGFLVXXXXXXXXXXXXXC---QSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQC----RQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKE--KKQIILNNQAATVVQKYFKSY----ICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKK----YLSYRHSV-----------------------IVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGF-IKRK---IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFR----KHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHF---------ICQKNAAIK------------------LQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGF---NAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHF---RKYLIIRRIDLEQK-AARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRN----RFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRY----ICISKFKMIKSATLIIQKHIRGIFVRLKYK---------KIIKLVVFIQKNIRANIVRTRFL---NIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFL----IRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVL-----------KRSAVVIQR 6351
D+ W ++QE F WLN I KT + ++N P E A +L SE V AI+K+ E+ L KD +K + + +++YN WL + + +SL N++ FI ++LWN DIA ++R + + +L++ L++ L +V LD AK + + D LF KD+ K+S E+L F+ FL GEG++ + L V+H+QT DE+DF V+NL+ D+ GVRL R ++L N D+ KLR PA+ +K N+++ ++ K G + G I I HREKTL LLW + +D ++ D+L EI ++ + +LL+ WV +VC YN V N + + DGR C LIH+Y P Y+ + I TT T S FD E LLENEK+NF + S ++ +GG P ++ N IP + ++ L+F +RL+DL RAA IQ WRKY+ K H K I+Q V FL ++ + ++ Q +R LA+ ++ K+A LIQ +RRY R R+ K+K +++LQS R + +Y + + + IQ + R YL R Y+ ++ ST IIQ + + R K KA V++Q AFR + R+ + +A+IIQS+YR R Y+ +R V+IIQK ++ ++R S + IQK Y++G I R N+L+ ++A L+ F Y R +Q FL ++ ++I Q ++R R + +K+A+IIQ F+ Y FA K + +SA I++Q+ R + R+ + ++ + I IQ +R Y +K+FL + I +Q V+ +K YL ++ + L IQ+ + + + ++ + C Q+ VR YL++KQ RK+ I +Q +FR AR+ +L K IV+Q Y ++ R+ FL++K +Q R R+ + A + IQ FR + K Q +L Q+ +Q+++++Y + F K K +V +Q R RKQ ++E + + +QS RM +K+++ A L I + + + A +K Y+ RH+V I+IQ+ +R + +K + +K +A++IQKY R + I R+ +Y A+ +Q RG VRK + +++A IQ YR+YK +K + R +AI+IQ+ +R ++ ++Y +K I IQS+ R + + M +AAT+I+ + K + R Y T R++A++IQ R Y K + R Y L A ++Q RG VR+ + Q A +IQ+ YR + +++F + Q+ A+K +Q RG R++ L+Q + + R+ + L+ ++I++Q+ +R H +FL+++NA I IQ + RR+ K R+ A+ IQ R ++YQ A++++Q+ + R + R+ L Q+ +A I+Q +RG R H +S IQ+ F++ L+R++++ +++ TIF+Q R I +FL L+ + I IQ R +K + ++A + IQ FR + TFQ K+ASI+IQ+++R Y + K +R+N YIR++ + + +K +K+ L+ +KH I ++ Y+ K+ IQ+ RAN + + +KK F M+ + K Q Q+ +IQK+C+ F RK +L +++ ++ IQ+ +R+ A R+ +I +QS RG + Q M A LIQ + + + Y+ + +++ +Q + R ++ RK FL ++ + I RG+ VR Q +K ++E + A+I Q+ CY K +Y ++S ++IQ+ ++ L R+AV IQ+
Sbjct: 692 DERWKEKQEQGFTWWLNFILTPDDFTVKTNISEVNAATLLLGIENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVKAIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGEL--ISLEDNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYAKISRLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRH-QEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQR-KMQSQVKATVILQRAFREWHLRKQ-AKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVL--QSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGK-------------------MQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTY---RAAKLQREN------YIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIK-KQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRT-----QAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVR-------QKLKNVSEEKM-----AAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQK 2823 HSP 2 Score: 380.563 bits (976), Expect = 1.925e-104 Identity = 501/1967 (25.47%), Postives = 886/1967 (45.04%), Query Frame = 1
Query: 2014 RAASCIQRVWR----KYRTFYLYKT--HFIAHY-------------KEVIIVQSIVRRFL----CLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIR----GYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVV--HKV--LFKR-------------------KLEKRLRSCIIIQKYIRGF----INRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKK----EFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVR--SIICQKN--YLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQK-----------------------YIKMHQCRQKFLKLKSQVITIQKNIRAL----LQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKE-SVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRH-SVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCS----QTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQF---------RKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGY----LIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVR----------------RYCQMKLYRDT---------RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIR----------------RIDLE--QKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYL----IRKKYLEIRQKTIFIQCLVRR--------------------------YISRNRFLRLKMSVIIIQKVTRGYF----THRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL-----VVFIQKNIRANIVRTRFLNIKKSII----------------------NIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFL-AKRSYQRNLSI-----IIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKI----LQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY----------------CLLK--SYTLLIQQRWRFIVLKR------SAVV-IQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELT---VAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSE-FIKLVKNLL--YRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSISNSQYSISKDSNIKDSV-SKYRQQLSSRCENIVGSISNSDKILEQMRLNPSWDLKRRFRPNSNSKKTLSTKLGSTNSLQENNLS 7125
RAA IQ WR + R L KT F AH K +I+Q+ R ++ L ++ + +I+ QS + AR + S I IQ YR Y+ + + +K+AT+ LQS + +K YL + + L IQ R R Y ++R+S +Q +V+GYL RK+ KA++ +QS FR R+ Y KA ++IQ++Y + R+ +L ++K+ +Q +KV L K+ K + L+S I IQ++ R + R +FLK K+AV L+ + G+ RKQ + + + +Q RM + F + + +A++IQ++F+ + A + E++ + A +++Q+ + RR+ Q AIIIQ +R + +KK+ I +A++IQK R SI ++N YLK K +V+ +Q +G V+K K + QS R Y +K+Y R S IIIQ+ +R I K++LN +K I +Q KMHQ R + ++ I IQ RA +QR +Y+ KAV +Q FR + ++ + AAT++Q ++ Y + F K+K+ + TV Q+Y QFQ RY K + + I +G AR ++L H + +IQ FR M R+ FLS+K +AI+IQ+ R + K + Q IK IQ + R +++RK + H++AT IQ +R +++ + + A++VIQ+Q+ R+HY+RQ R + +Q+ R + K M +AT IQ + ++R+++++ +++ + +Q+ R + + L + ++ RK AA IQ R +V+K++ Q+A +IQ +R + F K+A+I +Q++ R Y L R+N+ + +++Q+ KG AR+ ++ +SI++Q +R + + + KL+ A+ IQ+ R C ++D A+I+IQK+ + F R Y + +QR +RK +R R D++ +AA +IQ+FYR + + + +K + V IQNY++ Y+ RK +L +++ IQ R Y S+ ++ ++ ++IQ+ + +Y Q +A + IQK F R K + K A++ IQ + + R+ F ++++ + +Q Y R + +F + + A +++Q H R F+ K+++ + L V+ IQ + I + +F IK S I IQ++YR +K Y + +++ +IQ + R RFL ++++ IIIQ+ +R L AK +++ L I +Q+ RG + + + ++A ++IQK ++ KH +I +KS + LQ +RG+L+RK FL+ + ++ N + + + A +N K++ + I IQ +FR +Q++R+ CL + +IQ+ R +L++ S ++ IQ +WRG R + K I IR NR + N + AL L LT ++ +L L LE VT LS C+ + +S A + L+ CNR + +EV+ + V N+ K V E I ++ LL YR +K KG +IF TC LL +L+K +N + S + D + S Y+ L++ + N+++IL + + N S + F P + + + ++L L+ +N+
Sbjct: 1561 RAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQ--------------------RYNKLRHSVIYIQAIFRGKKAR-RHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIK-IQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQ-----RHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATIC-----------------AKHKLYQFLHLRK--AAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRK-LETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRA-FLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTK----IKAIRLSLQVVNREIREENKLYKRTALALHYL----LTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIFVLIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELLQIYREKPGNKVADKGGSIFTKTCCLLAILLK-----TTNRASDVRSRSKVVDRIYSLYK--LTAHKHKM-----NTERILYKQKKNSSISIP--FIPETPVRTRIVSRLKPDWVLRRDNME 3457
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. TrEMBL
Match: C3ZHZ0 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_88778 PE=4 SV=1) HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0 Identity = 628/2379 (26.40%), Postives = 1104/2379 (46.41%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIF--NTHLSKTKVEDINKNMPIYI---------EATKLLLSECKVA--IEKINSEVTKDSLKFKDDIFFKSGKHHRD-LTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNE--ACFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVT-YSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTT------------LTSANLFDKE-----ILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYL----VQKNYLKIYRSILIIQNNIRGYLCRSN--------------------------------------------------YKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRT----YLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLR--RKQFLKMRNSVILLQKNLRMLSLRN--SFLXXXXXXXXXXXXXXRYFA-------KKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSII----CQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARK----QFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCK---EKKQIILNNQAATV-VQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMII----TKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKI----YCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIR----QQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYK-RKLLAATL-IQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKN----FTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQ----MKLYRDTR---NASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFR----------KYLIIRRIDL-------------EQKAARII----QNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEI----RQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKT----FQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKH---------------------------IRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKN----YQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRT---ATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALT-DLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK-AGVLNFDVIGSEFIKLVKNLL--YRNINSKRGTKGITIFCHTCLLLVLLIK--------MEQKSISNSQYSISKDSNIKDSVSKYRQQLSSRCENIVGSISNSDKILEQM--RLNPSWDLKR 7041
D+ W+++QE F++WLN I NT + + M Y A LL +A I ++ EV L+ + D + + R + +++++Y+ WL + V L +N+ A +F+ ++L N DIA++ + K + +L + L++FL++V+ +D AK + D LF +N+KSS E+L F+ +L GEG++ + S SV+H QTA+ E D+TV NL+ D+ DG+RL R ++L N + SKLR PAV +K N +++++A ++AG ++ T G +I+ I G +EKTLALLW KLI ++ V N S + DGR CLL+H+YLP+ L + EI +TT T A + + LL +EK NF++ K+ ++G P +L N IP + +MAT+++ +R+I+L RA IQ WR+Y + + + E ++ I Q+ V+ + R + + KSA IQ R + R +Y K + A ++LQ R +L Q+ Y + R+ + +Q +RG R Y+ +R +T +Q V+G L R+ K K+ IQ+A RG+ R+ Y Q +AA+ +Q R+ + +T Y ++R++ I +Q V ++ +R L+++ +S IQ +RG+ R+ ++K + A IL+ Y +L R +++ R L R + + + +R+ A + + + KSATI +Q VR ++ R+ Q +A IQ R ++ R++++ Q +AI +Q+ VR+ + Q+ Y +++S + +Q +G +V++S ++ Q+ VR++ ++QY+K R++ II+Q+ RA ARK ++ + R+ TI +Q ++ R++ + + IQ R Q +Y K A IQ++FR+ K E++ + + ++AT+ +Q + + +K ++ +S T IQ R R+Q+ K+ + I LQ ++R + +++YQ +T+ + V+G RK S +IQ + R + R+ ++ + +AIV+Q Y+R +KRK Y + A +Q +RG LVR++L H+SAT IQ R + R+ ++ +R A I++Q+Q R H R Q+Y R+ I +Q+ +R ++ KQ + AAT IQ +G+ KY + + IIQ+ R + + + + R L +AT+ +Q RG LVRK + + K+ IIQ R T R ++ Q+ AA+ LQ IR +L RK + R I +Q+ ++G I R+ ++ S+ +Q RG+ A ++++K + A+I +Q+ VR + + M + R R ++ IQ VRG+ R +Y +Q AAI+LQ+ R KY +RR + QK A+++ + +RG+ + K + IQ F+A+ + ++ +I + TI +Q VR + R R S IQ RG+ ++Y+KQ++A I +Q R + + KT +QN++ A+I +Q R +R+ K+ + KIQ+ R + + K+K IK AT IIQ+ +RG+ VR ++ K IQ +R I R +++ +++ I +Q R H K YQ ++++ +Q R F+AR++ ++ +IQ FR FL +R Y + + +Q+ VRG A+ YQ++R A ++IQ T +G+ R K+LQ SV R +L RK +L+L+ A + VR + QK +RL A++ +Q+Y R Y+ K+ L+IQ+ K++ +V+Q IWRGR +R ++ K+I I+ R + + A R ++ + + AL LK L+ +L L S+E VT LS C+ L++ A +++ L+ CNR + E++ IS+ NL K + V+ ++ + +L+ YR K IF TCLLL L + S++ S+ + N K +S+ +Q++ S+ + + L QM + P+W L++
Sbjct: 629 DERWMQKQERAFIQWLNFILIPNTLAPQPRRNGTAVQMCEYAVLCNLNQLRRAACLLFQSEPMARVIHRLEEEVETGRLQVRADRHLHADQGIRQAILDMLLSYSPLWLRIGLETIFG---EVLPLQHNDDVAGLSRFLLNRVLGNSDIAQQFSHPTVPHMYKTGYAAALAKFTLKKFLTLVFFMDRAKLTRLIDQDPCLFCIHANIKSSKELLLTFSREYLSGEGDVTRHLSFLGYSVTHQQTALMEMDYTVQNLATDLRDGLRLNRAVELLTKNWTLSSKLRAPAVSRLQKIHNTKVSLEALQEAGVSLDTGLRGGKIEARDIVEGRQEKTLALLW---------------KLI-------------------------------FHFQVDNFSMSFSDGRVLCLLVHHYLPDLLPVEEICMDTTQSYITNYSGQAGTTQAECPETDKDRLKELLAHEKSNFKLVNQKVLELGTIPPLLCATDMSNTIPDQKVVMATVSYLCARVINLSQKVRAVRIIQAAWRRY-----HPKPAVGEWTE------------------DVQTATIRLQAAVRGMIVRRSLQRQHKSATTIQAAVRGWTARQQYMKQRQAAIILQQQVRAHLKRKTAQQKYQHVRRATICLQAAVRGMYVRRRQKQAQLAATKIQACWRGHQQLIKYKAIKLAAAIIQQRFRAFKLMQEEQHMYRSLRSATIHLQAAVRGMLVRRSLRKQHKSATTIQAAVRGWTARQQYMKQRQAAITLQQQVRAHLACKTAQQKYHHVRRATIWLQAAVRGMIVRRSLQRQHKSATTIQAAVRGWTARQQYMKQRQAAIILQLYVRAHLAPVRGMYVRRRQKQAQLAATKIQACWRGHQQLIKYKAIKLATTIIQQRFRAFKLMQEEQHMYRSLKSATIRLQAAVRGMLVRKSLQRQHKSATTIQTAVRGWTARQQYIKQRQAAITLQQQVRAHLKCKTAQQKYQHVRRSTIRLQAAVRGMIVRRSLQRQHKSATTIQAAVRRWTARQQYMKQRQAAIILQQQVRAYLARKTAQQKYQHVRRSTICLQAAVRGMYVRRRQKQAQLAATKIQACWRGHQQLIKYKAIKLATTIIQQRFRAFKLMQEEQHMYRSLKSATIRLQAAVRGMLVRKSLQRQHKSATTIQTAVRGWTARQQYIKQRQAAITLQQQVRAHLKCKTAQQKYQHVRRSTIRLQAAVRGMLVRKSLQRKHKSATIIQAAVRGWTARQQYMKQRQAAIVLQLYIRAHLKRKTAQQKYQNIRRATIRLQAAVRGMLVRRSLQRQHKSATTIQAAVRGWTARQQYMKQRQAVIILQQQVRAHLKRKTAQQKYQHVRRATICLQAAVRGMYVRRRQKQAQLAATKIQACWRGHQQLIKYKAIKLATTIIQQRFRAF---------------------KLMQEEQHMYRSLRSATIRLQAAVRGMLVRKSLQRQHKSATIIQTAVRGWTARQQYMKQRQAAVVLQLYIRAHLKRKTAQQKYQNIRRATICLQAAVRGMIVRRSLRRQHKSATTIQAAVRGWTARQQYMKQRQAAIVLQQQVRAHLKPVRGMIVRRSLRRQHKSATTIQAAVRGWTARQQYMKQRQAAIVLQQQVRAHLKRKTAQQKYQHVRRATICLQAAVRGMYVRRRQKQAQLLLPRFKLLWRGHQQLIKYKAIKLATTIIQQRFRAFKLMQEKQQIFRSCKSATIRLQAAVRGMLVRRSLRRQHKSATTIQAAVRGWTARQQYIKQRQAAIVLQLYVRAYLKRKTAQMNYQNIRRATICLQAAVRGMYVRRRQKQAQLAATKIQACWRGHQQLVKYKAIKLATTIIQQRFRAFKLMQEEQHMYRSCKSAAIRLQAAVRGMVVRKSLQRQHKSATIIQTAVRGWIARQQYMKQRQAAIILQQQVRAHLARKTAQQKYQHVRRATICLQAGIRGFLARRQLMKWIHASTVIQASFRCFLQRRRYLCIRAAVCRLQAAVRGWTARRTYQQVRVHHRAAVVIQSTYRGFATR---KVLQASV-------RAWLQRKHYLQLRQAVCKLQAAVR------YHQK--------------QRLTAAVVLQSYVRMYLAKK---------LMIQR-------KKAVIVMQAIWRGRHVRKNIKNKRI--RIA--RAKILAAQRAATEDKKLCNMTATALNLLLKYKHLST--ILDALRSMEVVTRLSAVCCERLVQGGAVQVIYTLIQSCNRSLPCQEMIKYSISILLNLAKNPATVAAAVVQEGGVETLVSLMAIYRE-------KDDVIFGQTCLLLTLFCNNAAYQKEVLNMPSVTQKLQSLYRLVNRKAGMSRNKQRMGSQEDK-----RRTSTALVQMVHHIKPAWILRK 2850
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. TrEMBL
Match: A0A3B3T4R3 (Abnormal spindle microtubule assembly OS=Paramormyrops kingsleyae OX=1676925 PE=4 SV=1) HSP 1 Score: 659.833 bits (1701), Expect = 0.000e+0 Identity = 651/2539 (25.64%), Postives = 1115/2539 (43.91%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIF-------NTHLSKTKVEDI--NKNMPIYIE-------------------------ATKLLLSECKV-AIEKINSEVTKDSLKFKDD-IFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEA-CFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFE--------------------NPIXXXXXXXXXXXXV---WVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT-------------------------SANLFDKEILLENEKRNFQIFFSKLKQIGGAP-IILPKE--NEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCR-----IRYEKIK----SATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYL----ARKKFVKLTKAIVVIQSAFRGY----AKRRN-----------------YTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQ---------------KVVHK------------VLFKRKLEKRLRSCIIIQKYIRGFI----NRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFA-------KKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKN----YLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRA---------------------------ISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALL----QRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQ-------------------------------------KY-------------FKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIIT----KKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQK----YLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIR----QQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLI----RKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYC----QMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAAR----IIQNFYRGYT----IRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGY----FTHRKYVKQKKAVINIQKNFRRFS----------------------ELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKM----IKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNY-----------------QLMK----------QSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQ-------------------------------------------------RNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQR----FIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKI-----------------------FAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLK--RSAVVIQRIWRG-----RQLRCH-----LNAKKIGHEISEIRN--RFIEANRRFSKFNTVRYIGKKALTDLKESELTVAK----------------VLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSE-FIKLVKNLL--YRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKS 6873
D+ W+++QE F W+N NT ++K + N P I A L SE V AI ++ EV L + D +K + + +++YN WL + ++ F + L SNN+ FI ++LWN DIA + R + + +L+ L++ L +V LD AK++ I D LF D+ K+S ++L F+ FL GEG + + L VSH+Q +DE+DF V NL+ D+ G+RL R+ ++ + + KLR PA+ +K N+++A++ +D G + G ID I GHREK++ LLW ++ +D ++D +KL EI + P + S L + WV +VC YN+ N + + DGR C L+H+Y P +L L I+ +TT T D + LLENE+RNF++ + + +GG P +I P + N IP+ + + L+F +RL+DL RAA IQ WRKYR + RR L K ++K+++ VKR+L R R +++ SAI++Q +R +L R R EK++ SA +V+Q+ +RRYL K + ++ ++IQ +R + + ++R+R + Q+ K L R++++ L A + +Q +FR + + RRN T Q AA+ IQS+YR VC R Y + ++ +IIQ K+ H L +R LE R + +IIQ++ R R +LK K A L+ + GY+ RK+ + I++Q RM R FL + +RY A K E+VA + + + +Q R ++RR+ + L AA +IQ FR YSV+ +F ++ +A+V+Q R+ + +N YLK +++++ +Q +G V++ K+ + Q+ + ++ ++ Y+ +R++TI++Q+H+RA R+ ++ ++ + V+Q Y +M++ R F + + IQ+ RA + QR Y++ K++ + IQ FR K + ++ ++AATV+Q KY F+ ++Q R+M+ + +IQ++ RK++ + + +Q + R + ++RYQ +AA++TI +G RK+ R S +IQ FR + R F++ K +A+VIQ+ +L G R+ + + VIQ RG R + H +A +I+ +R ++ F R AA VIQ+++R +R Q+Y + IQ R + A Q+ K M +AAT IQ+ + + RK++V+ R +A++IQ + +++ K MR+ Y K AA IQ RG R++++ E+KA +IQ R H R+ + AA +Q+ R + + N R I +Q +G AR+ + ++RS++ +Q FR A K++L LK+A + +Q R Q +LY R+A++ +Q RG+ R +RQ AA ++Q FR RR ++ +A R IIQ YR Y R FL +N+ ++IQ F+ ++KK + IQ R + R F+RL + ++Q+ R KY++ K+A +Q +FR + + F ++A+++IQ FR + +R +F+K + + + IQ + R K + I+ A +++Q RG+ R + K + V IQ +R R FL+++ +++ +Q+ YRM + + + Q M+ +S+ VIQ R + RK+FL+ K + I IQ F++ + ++ +Q R + +Q+ +G L + K+ R A + IQ +G+ R+ K+ + +V+ LQR RG R F K+K A++ + RG L R ++ Q ++ +A E+ RK++ + I IQ + R IQ++RY + + +Q+ R + + R++ +IQR R R+ R L A GH ++ + + RRF K N++ +KE + K +L L LE T LS E C+ L++S A ++ L+ CNR V +EV+S I V NL K V G E ++ + LL YR K KG +IF TC LL +L+ Q++
Sbjct: 695 DERWMEKQERGFTMWMNYALTPDEFKVNTEVTKVNAMSLAFQSNQPFNISKAPTKEEVSFRTYTARRRLNRLRQAACLLFTSESMVKAIRRLELEVEARRLLVRRDRHLWKDIGQRQKVLNWLLSYNPLWL----RIGLETIFGEMIPLESNNDVMGLAMFILRRLLWNPDIAAEFRHPKVPHLYRDGHEDALSSFTLKKLLLLVCFLDKAKESKIIEHDPCLFCMDAEFKTSKDLLLAFSRDFLSGEGILPRHLGYMGLPVSHVQMPLDEFDFAVKNLAVDLRCGIRLVRVMELFTQSWSLSQKLRVPAISRLQKVHNVDIALQVLRDRGVDLKDEHGGAIDSRDIVDGHREKSITLLWKIIFAFQVDVLLDEEKLKEEISFLQRMWRSKQELAAWKQHRNVVPKPQQAKSEESAAKLTLLMHWVNAVCAFYNLKAENFTVSFSDGRLLCYLLHHYHPCHLPLEAISQSTTQTVECDQRGRVGLNCSFSDSDSSLNNGPGTSLDYKELLENERRNFELLHAAVTSLGGIPAMITPTDMSNTIPNEKVVTCYLSFLCARLLDLRAESRAAWVIQGTWRKYRL-------------------KMQRRLLKEKNIAAVKIQV-----AVKRFLLRRREERLQASAIVLQAAWRGHLVRQEIRQQRMEKLRILQDSAAIVIQAEWRRYLAVKRFQRLRHHAVVIQARVRMKVAVTAFRRLRWAVMTFQQRRKASLLAKEHRQRYLSLRNAAITVQKSFRKWKVLSSIRRNNAAVVIQTAFRKWLTQKRTCQAAAALRIQSWYRMLVCCRRYAKVLQNAVIIQAWYRGFKERKIYQILKLQHSRAAIIQRTFKAFALRRRFLEVR-HATLIIQRWYRACKQKQRERLQYLKMKVAAVTLQAAYRGYVARKEKRVQHKAAIVIQAAFRMSLTRKRFL---LLRRAARDIQRRYRAKLLGEKQKMEYVALRHSAVKLQALWRGRVERRRIERLHKAAALIQSHFRRYSVQLQFRLKRRAALVLQDKFRAYVFGRNVRQQYLKKREAIITLQAGFRGMKVRQEMKEKHRAASLIQATFKAFIYKRNYMLLRRATIVVQQHYRAHLLGQHQRRQYNRLRQAAVKLQASYRRCKVRRDLMHKQRASAVIQAYFRMYKARMSFNAARFAAVIIQRRYRAWMEGRCQREWYLRRKESALVIQSSFRGLKARLKVKEMHKAATVIQACYRRHKRVTQFNKLRWAASVIGQRFKATQLKNAQVRKYEAMKNAAVRIQSAFRGMKTRQQVREMQNAARIIQRHYAAYSMRKRYLQVKAAAVKIQRQYRAHLAARLQQQRYQSLVAASVTIQAAYRGMKVRKELQRMRRSATLIQAYFRMYRKRMPFIAAKLAAVVIQRQYRCHLEGKRVREDFLKLQHSAVVIQAAFRGKRARCEIRRMHSAALVIEGCFRMWQCYTQFQKMRWAARVIQERYRASRMRNLLMQEYRVKKTSANIIQLAFRNYKARQQIKTMHRAATSIQRSFRTFRTRKRFVSLRAAAIVIQLRYKAFMAAKR-------------------MRAEYLAKHNAAMTIQAAFRGVKARRQLLRERKAATVIQVAVRRHQARTFHRKLQWAADVVQRRYRANKLMVKEKHNLALKRQAAICIQGAFRGMKARQRFMRVRSAACTLQTAFRARAARKQYLSLKSAVLAMQLQYRAVAAGRRQRELYLHVRSAAVTLQAAYRGWRTRQMIRRQHAAATLIQSLFRG----RREAIKYQAMRLSTLIIQQHYRSYLQSKRERERFLQLRNAAISIQAAFRRRRVQKKLARWHRAATLIQATFRMHQQRVVFVRLHWAATVLQRRLRAQKLRDVQLEKYMRMKRAATCLQASFRAVKARRLAKKKRAARAIQSFLQMSVDRRRFLRCRSAAVVIQSAFRGHYIRNQFRKMQTSSLLIQRWYRSCRTTQKLRADYLSIRQAAVMLQSAYRGLLAR-RTAKCERSAVKIQSVMRMLPYRKSFLHLRSNVVKLQASYRMCMDRRRFLSYRMAAVTLQRRFRARQEMRAQKEVYLKTLKSVQVIQAQLRGHVERKKFLKCKKSAITIQAFYQGMVQRKYFQQQKASATKIQEFYRAYTLGRKDRERYMQMRKSAVLIQAAYRGHQGRQLARRRQAAVKIQAWFKGSLTRRKFSAQRNAAVAIQSAYRGHVQRRDLKLRRAAVLVLQRRFQALQRGKAERDAFRKMKMATLTLQAFGRGWLARRRMKQEAQARRVKCFSAAAYHHLCAIKIQRAVRAHWALESARKQMSSVICIQKWLRTRIQRKRYLEDREKLIKLQRTVRIWLSRRHRASTIIQRAVRKFLTKRREQRVQHGIIKLQALWRGHRSRQLHDTSKVAAMRRRFRKINSM----------VKEEDKLCNKTSTAIDYLLRYKHFSYILAALKHLETSTRLSPECCEHLVKSGATFVIFTLIRSCNRSVPCMEVISYAIQVLLNLSKYDKTTEAVYGVENSVETLLELLQIYREKAGDKVADKGGSIFTKTCFLLTILLHDRQRA 3167
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. TrEMBL
Match: A0A3B3T4M1 (Abnormal spindle microtubule assembly OS=Paramormyrops kingsleyae OX=1676925 PE=4 SV=1) HSP 1 Score: 658.292 bits (1697), Expect = 0.000e+0 Identity = 651/2539 (25.64%), Postives = 1115/2539 (43.91%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIF-------NTHLSKTKVEDI--NKNMPIYIE-------------------------ATKLLLSECKV-AIEKINSEVTKDSLKFKDD-IFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEA-CFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFE--------------------NPIXXXXXXXXXXXXV---WVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT-------------------------SANLFDKEILLENEKRNFQIFFSKLKQIGGAP-IILPKE--NEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCR-----IRYEKIK----SATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYL----ARKKFVKLTKAIVVIQSAFRGY----AKRRN-----------------YTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQ---------------KVVHK------------VLFKRKLEKRLRSCIIIQKYIRGFI----NRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFA-------KKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKN----YLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRA---------------------------ISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALL----QRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQ-------------------------------------KY-------------FKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIIT----KKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQK----YLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIR----QQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLI----RKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYC----QMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAAR----IIQNFYRGYT----IRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGY----FTHRKYVKQKKAVINIQKNFRRFS----------------------ELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKM----IKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNY-----------------QLMK----------QSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQ-------------------------------------------------RNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQR----FIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKI-----------------------FAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLK--RSAVVIQRIWRG-----RQLRCH-----LNAKKIGHEISEIRN--RFIEANRRFSKFNTVRYIGKKALTDLKESELTVAK----------------VLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSE-FIKLVKNLL--YRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKS 6873
D+ W+++QE F W+N NT ++K + N P I A L SE V AI ++ EV L + D +K + + +++YN WL + ++ F + L SNN+ FI ++LWN DIA + R + + +L+ L++ L +V LD AK++ I D LF D+ K+S ++L F+ FL GEG + + L VSH+Q +DE+DF V NL+ D+ G+RL R+ ++ + + KLR PA+ +K N+++A++ +D G + G ID I GHREK++ LLW ++ +D ++D +KL EI + P + S L + WV +VC YN+ N + + DGR C L+H+Y P +L L I+ +TT T D + LLENE+RNF++ + + +GG P +I P + N IP+ + + L+F +RL+DL RAA IQ WRKYR + RR L K ++K+++ VKR+L R R +++ SAI++Q +R +L R R EK++ SA +V+Q+ +RRYL K + ++ ++IQ +R + + ++R+R + Q+ K L R++++ L A + +Q +FR + + RRN T Q AA+ IQS+YR VC R Y + ++ +IIQ K+ H L +R LE R + +IIQ++ R R +LK K A L+ + GY+ RK+ + I++Q RM R FL + +RY A K E+VA + + + +Q R ++RR+ + L AA +IQ FR YSV+ +F ++ +A+V+Q R+ + +N YLK +++++ +Q +G V++ K+ + Q+ + ++ ++ Y+ +R++TI++Q+H+RA R+ ++ ++ + V+Q Y +M++ R F + + IQ+ RA + QR Y++ K++ + IQ FR K + ++ ++AATV+Q KY F+ ++Q R+M+ + +IQ++ RK++ + + +Q + R + ++RYQ +AA++TI +G RK+ R S +IQ FR + R F++ K +A+VIQ+ +L G R+ + + VIQ RG R + H +A +I+ +R ++ F R AA VIQ+++R +R Q+Y + IQ R + A Q+ K M +AAT IQ+ + + RK++V+ R +A++IQ + +++ K MR+ Y K AA IQ RG R++++ E+KA +IQ R H R+ + AA +Q+ R + + N R I +Q +G AR+ + ++RS++ +Q FR A K++L LK+A + +Q R Q +LY R+A++ +Q RG+ R +RQ AA ++Q FR RR ++ +A R IIQ YR Y R FL +N+ ++IQ F+ ++KK + IQ R + R F+RL + ++Q+ R KY++ K+A +Q +FR + + F ++A+++IQ FR + +R +F+K + + + IQ + R K + I+ A +++Q RG+ R + K + V IQ +R R FL+++ +++ +Q+ YRM + + + Q M+ +S+ VIQ R + RK+FL+ K + I IQ F++ + ++ +Q R + +Q+ +G L + K+ R A + IQ +G+ R+ K+ + +V+ LQR RG R F K+K A++ + RG L R ++ Q ++ +A E+ RK++ + I IQ + R IQ++RY + + +Q+ R + + R++ +IQR R R+ R L A GH ++ + + RRF K N++ +KE + K +L L LE T LS E C+ L++S A ++ L+ CNR V +EV+S I V NL K V G E ++ + LL YR K KG +IF TC LL +L+ Q++
Sbjct: 726 DERWMEKQERGFTMWMNYALTPDEFKVNTEVTKVNAMSLAFQSNQPFNISKAPTKEEVSFRTYTARRRLNRLRQAACLLFTSESMVKAIRRLELEVEARRLLVRRDRHLWKDIGQRQKVLNWLLSYNPLWL----RIGLETIFGEMIPLESNNDVMGLAMFILRRLLWNPDIAAEFRHPKVPHLYRDGHEDALSSFTLKKLLLLVCFLDKAKESKIIEHDPCLFCMDAEFKTSKDLLLAFSRDFLSGEGILPRHLGYMGLPVSHVQMPLDEFDFAVKNLAVDLRCGIRLVRVMELFTQSWSLSQKLRVPAISRLQKVHNVDIALQVLRDRGVDLKDEHGGAIDSRDIVDGHREKSITLLWKIIFAFQVDVLLDEEKLKEEISFLQRMWRSKQELAAWKQHRNVVPKPQQAKSEESAAKLTLLMHWVNAVCAFYNLKAENFTVSFSDGRLLCYLLHHYHPCHLPLEAISQSTTQTVECDQRGRVGLNCSFSDSDSSLNNGPGTSLDYKELLENERRNFELLHAAVTSLGGIPAMITPTDMSNTIPNEKVVTCYLSFLCARLLDLRAESRAAWVIQGTWRKYRL-------------------KMQRRLLKEKNIAAVKIQV-----AVKRFLLRRREERLQASAIVLQAAWRGHLVRQEIRQQRMEKLRILQDSAAIVIQAEWRRYLAVKRFQRLRHHAVVIQARVRMKVAVTAFRRLRWAVMTFQQRRKASLLAKEHRQRYLSLRNAAITVQKSFRKWKVLSSIRRNNAAVVIQTAFRKWLTQKRTCQAAAALRIQSWYRMLVCCRRYAKVLQNAVIIQAWYRGFKERKIYQILKLQHSRAAIIQRTFKAFALRRRFLEVR-HATLIIQRWYRACKQKQRERLQYLKMKVAAVTLQAAYRGYVARKEKRVQHKAAIVIQAAFRMSLTRKRFL---LLRRAARDIQRRYRAKLLGEKQKMEYVALRHSAVKLQALWRGRVERRRIERLHKAAALIQSHFRRYSVQLQFRLKRRAALVLQDKFRAYVFGRNVRQQYLKKREAIITLQAGFRGMKVRQEMKEKHRAASLIQATFKAFIYKRNYMLLRRATIVVQQHYRAHLLGQHQRRQYNRLRQAAVKLQASYRRCKVRRDLMHKQRASAVIQAYFRMYKARMSFNAARFAAVIIQRRYRAWMEGRCQREWYLRRKESALVIQSSFRGLKARLKVKEMHKAATVIQACYRRHKRVTQFNKLRWAASVIGQRFKATQLKNAQVRKYEAMKNAAVRIQSAFRGMKTRQQVREMQNAARIIQRHYAAYSMRKRYLQVKAAAVKIQRQYRAHLAARLQQQRYQSLVAASVTIQAAYRGMKVRKELQRMRRSATLIQAYFRMYRKRMPFIAAKLAAVVIQRQYRCHLEGKRVREDFLKLQHSAVVIQAAFRGKRARCEIRRMHSAALVIEGCFRMWQCYTQFQKMRWAARVIQERYRASRMRNLLMQEYRVKKTSANIIQLAFRNYKARQQIKTMHRAATSIQRSFRTFRTRKRFVSLRAAAIVIQLRYKAFMAAKR-------------------MRAEYLAKHNAAMTIQAAFRGVKARRQLLRERKAATVIQVAVRRHQARTFHRKLQWAADVVQRRYRANKLMVKEKHNLALKRQAAICIQGAFRGMKARQRFMRVRSAACTLQTAFRARAARKQYLSLKSAVLAMQLQYRAVAAGRRQRELYLHVRSAAVTLQAAYRGWRTRQMIRRQHAAATLIQSLFRG----RREAIKYQAMRLSTLIIQQHYRSYLQSKRERERFLQLRNAAISIQAAFRRRRVQKKLARWHRAATLIQATFRMHQQRVVFVRLHWAATVLQRRLRAQKLRDVQLEKYMRMKRAATCLQASFRAVKARRLAKKKRAARAIQSFLQMSVDRRRFLRCRSAAVVIQSAFRGHYIRNQFRKMQTSSLLIQRWYRSCRTTQKLRADYLSIRQAAVMLQSAYRGLLAR-RTAKCERSAVKIQSVMRMLPYRKSFLHLRSNVVKLQASYRMCMDRRRFLSYRMAAVTLQRRFRARQEMRAQKEVYLKTLKSVQVIQAQLRGHVERKKFLKCKKSAITIQAFYQGMVQRKYFQQQKASATKIQEFYRAYTLGRKDRERYMQMRKSAVLIQAAYRGHQGRQLARRRQAAVKIQAWFKGSLTRRKFSAQRNAAVAIQSAYRGHVQRRDLKLRRAAVLVLQRRFQALQRGKAERDAFRKMKMATLTLQAFGRGWLARRRMKQEAQARRVKCFSAAAYHHLCAIKIQRAVRAHWALESARKQMSSVICIQKWLRTRIQRKRYLEDREKLIKLQRTVRIWLSRRHRASTIIQRAVRKFLTKRREQRVQHGIIKLQALWRGHRSRQLHDTSKVAAMRRRFRKINSM----------VKEEDKLCNKTSTAIDYLLRYKHFSYILAALKHLETSTRLSPECCEHLVKSGATFVIFTLIRSCNRSVPCMEVISYAIQVLLNLSKYDKTTEAVYGVENSVETLLELLQIYREKAGDKVADKGGSIFTKTCFLLTILLHDRQRA 3198
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. TrEMBL
Match: W4Y9U0 (Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1) HSP 1 Score: 655.596 bits (1690), Expect = 0.000e+0 Identity = 585/2301 (25.42%), Postives = 1041/2301 (45.24%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTHLSKTKVEDINKNMPIYIEATKLLL-------------------------------SECKV--------AIEKINSEVTKDSLKFKDDIFFKSGKH-HRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNEACFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLF--------------------------ENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTL-------------TSANLFD----------------KEILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMK------------------------KSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQ----NNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLR----SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKM---------------------------RNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRA-LIQR---RKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKH---------------------------TKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQ-FLNF---RKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILN----NQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNI---------------------------RGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYI----RQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLL-----AATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQK-----NAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFN----AHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRK-----------YLIIRRIDLEQKA----------------ARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLI----RKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGY--FTHRKYVKQKK--AVINIQKNFR----RFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKM---------------------------IKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRM----HYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLK----YQKMRTATILIQKTVKGYFIR----KH------------------YKILQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLV-----RNHFQKNKQHM-------KIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKR-----------SAVVIQRIWRG-------RQLRCHL 6384
D+ W+++Q+ F WLN + + K D NKN + I+A L L C V ++K+ +EV K + + D + ++L LI+ YN WL + L ++ +F+ ++L N DIA H + + P + +L + L++FL +V+ LD AK + D LF KD+ VKSS ++L EF+ +LKGEG+I + S SV+H+Q +DE+DF V+ LS D+ GVRLAR+ ++L N + +LR PA+ +K N+E A K K+ G + G ++ I GHREKTL LLW ++ + + +++ + + EI + P LL+ W K+VC Y++ + N + + DGR CLLIH+Y P L IN +TTL +S N FD +E LL NE+ NF++ + K+ ++GG P+++ N IP + ++ +++ +RL+DL RAA IQ WR + K + K +QS +R FL ++ + ++ Q+ ++ +LA+ +++ K+A IQ +R Y R Y + +SAT++LQ+H+RR+ + + K+ +++ +Q + ++G R+ Y +R + ++QK +G L R+ V+ ++ V IQ+AFRG+ +R +Y +AV IQ+ + RR Y LR++ +++Q VL RK+ + + I IQ +R + R+ F++ K + L+ YL +K + ++ R + I +Q R R F+ +++ II+Q + + Y A K + + A +++QT+ RA L+ R RK+ R AAI IQ RCY R++F+ + +V+Q VR + QKNY +I+Q+ +V+Q KG+L + + + I QS VR L +++Y+K++++T+I+Q+ FRA+ KQ L++ R I +Q + + ++++ + ++ VIT+Q + R L R+ + + + A I +QR+FR+ +Q+ + AA +Q F+ ++ + + K + +V +Q R+ + R+Q+ + I+LQ++ R A + + + + Y A+ R SVI+ Q +R + RK+FL K +A++IQ RG+++ + Y A++ +Q RG+ RK LN+ +A IQ ++ RK + + A V+Q + R H + R+ + +T+ +I IQSL R + ++ + +AAT +Q K +I R +Y+ +++ +++Q R L + +I + R +R++L AA LIQ R + R+ V + A ++Q +RA + S IC K AAI LQ RG+L RK L+Q+ +GF+ ++ Y + + +++Q +R K++ ++ A+I +Q R + Q K+ +++ IQ RGF+ R +Y + AA +LQ+HFR Y+++ I Q A A IQ +RGY R + N+ + +Q F+A + R Y+ R I IQ R R F+ K S + IQ + RGY F H K +Q++ A IQK +R R +++ + + A+I IQ R +++R+ +K+ + +IQ + R + + +K +K AT+ +Q RG+ +R + I+ +R I R R+L++KK+ + +Q +R E Y + + + +Q R F+ RK IIQ +R F ++ Y + +II +Q+ +R L K Y M++A +++Q +G R KH Y + S I++Q R +L ++ + K+ +A ++ KH RG L R++ QK + + A+ K +A+I +Q+++R +Q+RRY ++ L+IQ+R+R +L R +A+ +Q ++RG R +RCH+
Sbjct: 798 DERWMEKQDRAFTCWLNYVLTPDIDTPK--DPNKN--VKIDAHLLCLEGASKVGPAPSREDISLRAYTARRRLNRLRRGACMVFQSEPVIRVMQKLEAEVEKGRIVVRSDKMLHADLGIKQELLNLILCYNPLWLRIG-------------LESDVCGMSRFVVTRLLGNPDIAAAHAHPTVPNLFGPGYQAALAQFTLKKFLMLVFFLDRAKLTRLIDHDPCLFCKDAQVKSSRDVLLEFSRRYLKGEGDITRHLSFLGYSVTHVQRPLDEFDFAVNKLSVDLRCGVRLARVVELLTQNWTLSRELRVPAISRLQKIHNVESAFKMLKERG---INVEGGGLNERVIVDGHREKTLELLWRIIFHYQVGVMLNDEHIREEIAFLTKNRKLKEKISALKEGGNQGPSHPSLDGPHLYFKSPQLMLLMDWCKAVCSFYDLQIENFTVSFCDGRALCLLIHHYHPSLLPYERINQDTTLMQFQREEREDDLNSSCNSFDGTWSHTFSPSTGKETNQEKLLANERMNFKLLYEKVNELGGVPMMVRSADMSNTIPDEKVVITYVSYLCARLLDLRQETRAARTIQLAWRAHHLRKEQKMRLV-REKAASKIQSALRAFLLKRRGERFGGAVLTIQTAIRGFLAKQTAKRLRQELAIRKQAQAATVIQVRRMIEQMKAARTIQSVWRGYHARQMYLRQQSATIILQTHYRRHCAVEGFRKLRGTVIKMQALYRSKVKGEAQRAKYCALRDAAVVMQKVYRGRLGRRD-VRRIRSAVTIQAAFRGHQQRASYMRLKNSAVRIQAHVKGVQSRRRYTQLRQAAVVLQTRYRGVLLGRKVCRDYNVTRGATITIQSAVRCYQERQRFIQTKQNIITLQSAVRRYLAQKNYRQLQQATKVMQTRYRAVLLGRRVYREYNISRGAAITIQSAARCFQERRRFIQTKQNVIILQSAIRGYLALKNYRQVRQAAVVMQTRYRAVLLGRQVCRKYNIQRGAAITIQSGARCYQERQRFIQTKRNIVVLQSAVRGYLAQKNYRQIRQAAVVLQTRYREVLLGRRLRSDYCIAKGAAITLQATWKGYLARTEFLQKKSAAIKLQSAVRCRLSRQRYMKLQEATVILQRRFRAVLQTKQAILDYCYTRGAIITLQAAFRGYLQKREYQRTRAAVITLQSSTRCYLARKDFTQKRSATILLQRRFRALVTGRQLHADYRCLRAAAITMQASFRCHVQRTWYLKQRSAVVAVQAEVRKRLARRQYLQLRSAAIVLQTRFR-------------ARMLMLQLTQDYKAK------RSSVILFQALYRGQVQRKIFLRQKSAAVIIQARTRGYLQHRSYMRVQQAVRTLQTRFRASMMGRACLEEYYLARGRIITIQALYRGYAARKMLNAQQAAAVTIQANFKCLIARKRYSSLKQAVSVLQTRLRAHILARKTRESFQKTKAGIIAIQSLYRGYAQRKELSRQHQAATLVQSSFKRFIARSRYLQLQQATLVLQTRYRS-LQLGRAVCRDYNIKRRAAITLQAAYRGCSQRQVLAKQRRAAVLIQAAVRAHQKRRLYVSLRNAAMVVQKRFRAQLL-SKRICMKYNIMRGAAITLQAAYRGHLQRKALARQYLAATLIQATFRGFVTKRWYSSVCKAVVVLQTRYRAHKLAQAVQKEYQIMRVAAITLQAAYRGHYQRKVLTLQHSSATKIQALFRGFVRRKRYLQVCHAARVLQKHFRALRLGKEVQQEYYMMVGAIVTVQAAFRGLVARRALHRHHEMATKIQACFRGYVQRIQYQKIANAALVLQRRFRALRLGQRTRGDYVFQRSSAIKIQAFYRCQRERKAFVTKKQSAVRIQAMIRGYLGFVHAKRFRQERTVAATAIQKQWRANALRDQQVRCYNIQRGAAITIQAAARTFLVRQSIQKQHRAATRIQCFYRCHRAVKSYKKTLDAIHVLQDQWRAHLLAKKFQEEYANLKKATITVQAVYRGLCIRRRIALEHAAATKIEATVRQFIARKRYLSLKKAAVVLQRRFRASKSCQVETLKYHITRGACITLQAAVRGFLTRKALKNSNRAATIIQSAYRSFRQQQKYNQERMVIILLQTRIRAYLVGKKVCRDYSAMKSAAVVVQSVYRGLMARRLAAKHRAARSIQSMFRMHLSRQMYLKQRSSAIKIQAICRMYLAKRFYKKVYSAVCVLQKHTRGYLEAKKTRRDYLQKKSSAIIIQSHFRRCIAERRYSKHRQAAICVQSHYRQMVQRRRYQTIRGAALVIQRRYRATILARVTQKEYHMARGAAITLQAVFRGYMQCCRYRNMRCHV 3055 HSP 2 Score: 467.618 bits (1202), Expect = 1.053e-128 Identity = 455/1799 (25.29%), Postives = 847/1799 (47.08%), Query Frame = 1
Query: 2101 VIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIR----YEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQ-KYVKGYLAR---KKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRL----RSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLR-MLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQK----NYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRA----ISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRS------CKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMII----TKKRYQKKIAATLTISKFVKGYFARKKYLSYRH-SVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTT----AIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQ----QYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLL-----AATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRA----HTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKL---------------------------RSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRY---CQMKLYRDTRN-ASIVIQKYVRGFLCRIK----YQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTI------------------RAHFLCQK---------NSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHR----KYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISK----FKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFI----ARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQK----TVKGYFIRKHYKILQKSVIQLQRFIRGFL-------IRKIFLKL-------------------KNASIIISKHVRGVLVRNHFQKNKQH----MKIFAQEN---------------------LRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRW-RFIVLK------------------------RSAVVIQRIWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESEL-------TVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSE--FIKLVKNL-LYRNINSKRGTKGITIFCHTCLLLVLLIK 6858
I +QS VR + ++F K II QS V+RYLA+ +++++ ++Q YR L R Y + A + +QS R + ++ +++ ++++I+Q+ IRGYL NY+++R++ ++Q +Y L R +K+ A + IQS R Y +R+ + + V++QS R + ++ Y +R++ +++Q +VL R+L + I +Q +G++ R FL+ KSA L+ L R++++K++ + ++LQ+ R +L + + L ++ + A I +Q R +Q+R++Q R A I +Q + RCY RK F + + I++Q+ R+++ + +Y ++ + + +Q + + + Y K ++ Q+ VRK L ++QYL++R + I++Q FRA + + + R I+ Q + R+ FL+ KS + IQ R LQ R Y++ ++AV +Q +FR+ C E + L +Q ++ Y +K + + IQ + LI RK++ + V +LQ+++R I T++ +QK A + I +GY A++K LS +H + ++Q+SF+ F+ R +L ++ + +V+Q R + C A +Q RG R+ L ++A LIQ R+++ R+ ++ RNAA+V+QK+FR + + +YN R I +Q+ R + + + AAT IQ +G++ ++ Y + ++ V++Q R + ++ Q + + + ++ R Y+RK+L +AT IQ + RG++ RKR + A R++Q +RA ++ + A + +Q RG + R+ +Q+ +G++ R YQK+ RSS+I +Q +R K F+ K +++ IQ +R Y K +R R A+ IQK R R + Y Q AAI +Q R +L+ + I + +AA IQ FYR + RAH L +K + +T+Q ++ IR++ I+ VR++I+R R+L LK + +++Q+ R + + KY + A I +Q R F K +N A+ IIQ +R + ++++ ++R + +Q+ IR Y+ K + +KSA +++Q RG+ R K + IQ R ++ R +L + S I IQ+ RM+ + Y+ + ++ V+QK+ R ++ R+ +L+ KS+ IIIQ FRR +A+R Y ++ I VQS R + + +YQ +R A ++IQ+ T+ +K Y + + + I LQ RG++ +R +K+ K A++ I +HVRG R H + +Q ++ FA +++++A +Q + R + + R+ L++ L++Q+ R++V K +A+ +Q +WRG ++RC + +KK+ S R R ANR ++ +K L + + L ++ ++L L SLE V+ LS C+ L+E+ A +L L+ CNR V +E++ ++ + N+ K V+ +E I L+ L +YR N+ IFC TC++L L++
Sbjct: 1619 TITIQSAVRCYQERQRFIQTKQNIITLQSAVRRYLAQKNYRQLQQATKVMQTRYRAVLLGRRVYREYNISRGAAITIQSAARCFQERRRFIQTKQNVIILQSAIRGYLALKNYRQVRQAAVVMQTRYRAVLLGRQVCRKYNIQRGAAITIQSGARCYQERQRFIQTKRNIVVLQSAVRGYLAQKNYRQIRQAAVVLQTRYREVLLGRRLRSDYCIAKGAAITLQATWKGYLARTEFLQKKSAAIKLQSAVRCRLSRQRYMKLQEATVILQRRFRAVLQTKQAIL--------------------DYCYTRGAIITLQAAFRGYLQKREYQRTRAAVITLQSSTRCYLARKDFTQKRSATILLQRRFRALVTGRQLHADYRCLRAAAITMQASFRCHVQRTWYLKQRSAVVAVQAEVRKRLARRQYLQLRSAAIVLQTRFRARMLMLQLTQDYKAKRSSVILFQALYRGQVQRKIFLRQKSAAVIIQARTRGYLQHRSYMRVQQAVRTLQTRFRASMMGRACLE--EYYLARGRIITIQALYRGYAARKMLNAQQAAAVTIQANFKCLIARKRYSSLKQAVSVLQTRLRAHILARKTRESFQKTKAGIIAIQSLYRGY-AQRKELSRQHQAATLVQSSFKRFIARSRYLQLQQATLVLQTRYRSLQLGRAVCRDYNIKRRAAITLQAAYRGCSQRQVLAKQRRAAVLIQAAVRAHQKRRLYVSLRNAAMVVQKRFRAQLLSKRICMKYNIMRGAAITLQAAYRGHLQRKALARQYLAATLIQATFRGFVTKRWYSSVCKAVVVLQTRYRAHKLAQAVQKEYQIMRVAAITLQ-AAYRGHYQRKVLTLQHSSATKIQALFRGFVRRKRYLQVCHAARVLQKHFRALRLGKEVQQEYYMMVGAIVTVQAAFRGLVARRALHRHHEMATKIQACFRGYVQRIQYQKIANAALVLQRRFRALRLGQRTRGDYVFQRSSAIKIQAFYRCQRERKAFVTKKQSAVRIQAMIRGYLGFVHAKRFRQERTVAATAIQKQWRANALRDQQVRCYNIQRGAAITIQAAARTFLVRQSIQKQHRAATRIQCFYRCHRAVKSYKKTLDAIHVLQDQWRAHLLAKKFQEEYANLKKATITVQAVYRGLCIRRRIALEHAAATKIEATVRQFIARKRYLSLKKAAVVLQRRFRASKSCQVETLKYHITRGACITLQAAVRGFLTRKALKNSNRAATIIQSAYRSFRQQQKYNQERMVIILLQTRIRAYLVGKKVCRDYSAMKSAAVVVQSVYRGLMARRLAAKH-RAARSIQSMFRMHLSRQMYLKQRSSAIKIQAICRMYLAKRFYKKVYSAVCVLQKHTRGYLEAKKTRRDYLQKKSSAIIIQSHFRRCIAERRYSKHRQAAICVQSHYRQMVQRRRYQTIRGAALVIQRRYRATILARVTQKEYHMARGAAITLQAVFRGYMQCCRYRNMRCHVVKMQARARGAMARRCFANMVREKEAAMCIQRHVRGYQTRKHLKAQRQARLKTLQAFADRTKAHLSVIRLQRAFRNFRLRMAFKQKMDAITTLQNWMRAKLLRLRFQKLRAAALVLQRAAKRYLVRKNVAATRLQSVARVWLAKRRVQKMHSAALRMQALWRGHRVRCSIKSKKV----SAARARCQRANRNVTE--------EKKLCNRTATALDYLLHYRSMHRILETLISLEVVSRLSAICCQRLVEAGAVPVLYALVRGCNRSVPCMEMIEIIVKILLNITKHDSTQHAVLDAEEAVITLLDLLQIYREKNA-------LIFCKTCVILGKLLQ 3373 HSP 3 Score: 405.216 bits (1040), Expect = 1.462e-109 Identity = 397/1526 (26.02%), Postives = 728/1526 (47.71%), Query Frame = 1
Query: 1999 LMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLC----RIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKK----FVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLR----SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLR----MLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAA---------------------------IIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXC----QSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQ-------------------------C--RQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILN----NQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRM----IITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIV-IQNSFRCFMYRKMFLSIKFSAIVIQKYLRGF-IKRKI---YCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLL--------AATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTET----RNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVR--RYCQMKL--YRDTRNASIVIQKYVRGFLCR-----------------------IKYQRQLLAAIILQRHFRKYLIIRRI----DLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYF----THRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRY-------ICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNI---KKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVR 6144
+ T YRA ++V RKY I +QS R + ++F K I++ QS V+ YLA+ +++++A+++Q YR L R Y K A + LQ+ ++ YL + +L+ + + +Q+ +R L R Y +++++T I+Q+ + L K+ + AI+ +Q+AFRGY ++R Y A + +QS R + R+ + R + I++Q+ ++ R+L R + I +Q R + R +LK +SAV ++ L R+Q+L++R++ I+LQ R ML L + K+ S I+ Q ++ +K F+ +KSA ++IQ + R +Q R + ++ A I IQ +R Y+ RK Q +A+ IQ N + +I +K Y +KQ+V V+Q + ++ + ++ + QSL R Y +K+ + ++ ++Q F+ AR ++L ++ T+V+Q + Q C RQ K + + IQ +RA +RR Y+ + A + +Q++FR+ K+I + AA +Q ++ ++ +K + + T+IQ R + ++ + K V++LQ++ R +K YQ A +T+ +G++ RK L+ +HS IQ FR F+ RK +L + +A V+QK+ R + +++ Y AI +Q RG + R+ L+ HH+ AT IQ +R Y R + NAA+V+Q++FR + Q+ TR +F +S I IQ + + ++ RK +VT+++SAV IQ +R YL + + + +++ + + + + AA IQ AR +LVR+ I + +A IQ FYR H + +A LQ R +L+ K F E + I VQ++ +G R+ +++ ++ R F A K++L LK A++ +Q+ R + CQ++ Y TR A I +Q VRGFL R KY ++ + I+LQ R YL+ +++ + AA ++Q+ YRG R + + +IQ+ F+ +L R+ YL+ R I IQ + R Y+++ + ++ +V ++QK TRGY T R Y+++K + I IQ +FRR + + + A+I +Q ++R + R+ ++ R + IQ RRY + ++ M + A + +Q RG +Y+ + VV +Q R + R F N+ K++ + IQ R + K+ + +Q+ K + F R + ++I +Q+ FR F + ++++ + I +Q+ +R KL +L++QK+R A +++Q+ K Y +RK+ + +LQ R +L ++ K+ +A++ + RG VR
Sbjct: 1741 MQTRYRAVLLGRQVCRKYNI----------QRGAAITIQSGARCYQERQRFIQTKRNIVVLQSAVRGYLAQKNYRQIRQAAVVLQTRYREVLLGRRLRSDYCIAKGAAITLQATWKGYLARTEFLQKKSAAIKLQSAVRCRLSRQRYMKLQEATVILQRRFRAVLQTKQAILDYCYTRGAIITLQAAFRGYLQKREYQRTRAAVITLQSSTRCYLARKDFTQKRSATILLQRRFRALVTGRQLHADYRCLRAAAITMQASFRCHVQRTWYLKQRSAVVAVQAEVRKRLARRQYLQLRSAAIVLQTRFRARMLMLQLTQDYKAKRSSVILFQALYRGQVQRKIFLRQKSAAVIIQARTRGYLQHRSYMRVQQAVRTLQTRFRASMMGRACLEEYYLARGRIITIQALYRGYAARKMLNAQQAAAVTIQANFKCLIARKRYSSLKQAVSVLQTRLRAHILARKTRESFQKTKAGIIAIQSLYRGYAQRKELSRQHQAATLVQSSFKRFIARSRYLQLQQATLVLQTRYRSLQLGRAVCRDYNIKRRAAITLQAAYRGCSQRQVLAKQRRAAVLIQAAVRAHQKRRLYVSLRNAAMVVQKRFRAQLLSKRICMKYNIMRGAAITLQAAYRGHLQRKALARQYLAATLIQATFRGFVTKRWYSSVCKAVVVLQTRYRAHKLAQAVQKEYQIMRVAAITLQAAYRGHYQRK-VLTLQHSSATKIQALFRGFVRRKRYLQVCHAARVLQKHFRALRLGKEVQQEYYMMVGAIVTVQAAFRGLVARRALHRHHEMATKIQACFRGYVQRIQYQKIANAALVLQRRFRALRLGQR---TRGDYVFQRS---SAIKIQAFYRCQRE-------------RKAFVTKKQSAVRIQAMIRGYLGFVHAKRFRQERTVAATAIQKQWRANALRDQQVRCYNIQRGAAITIQAAARTFLVRQSIQKQHRAATRIQCFYRCHRAVKSYKKTLDAIHVLQDQWRAHLLAKKFQEEYANLKKATITVQAVYRGLCIRRRIALEHAAATKIEATVRQFIARKRYLSLKKAAVVLQRRFRASKSCQVETLKYHITRGACITLQAAVRGFLTRKALKNSNRAATIIQSAYRSFRQQQKYNQERMVIILLQTRIRAYLVGKKVCRDYSAMKSAAVVVQSVYRGLMAR-RLAAKHRAARSIQSMFRMHLSRQMYLKQRSSAIKIQAICRMYLAKRFYKKVYSAVCVLQKHTRGYLEAKKTRRDYLQKKSSAIIIQSHFRRCIAERRYSKHRQAAICVQSHYRQMVQRRRYQTIRGAALVIQ---RRYRATILARVTQKEYHMARGAAITLQAVFRGYMQCCRYRNMRCHVVKMQARARGAMARRCFANMVREKEAAMCIQRHVRGYQTRKHLKAQRQARL---KTLQAFADRTK---AHLSVIRLQRAFRNFRLRMAFKQKMDAITTLQNWMRAKLLRLRFQKLRAAALVLQRAAKRYLVRKNV-----AATRLQSVARVWLAKRRVQKMHSAALRMQALWRGHRVR 3221
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. TrEMBL
Match: A0A3B4C7U1 (Abnormal spindle microtubule assembly OS=Pygocentrus nattereri OX=42514 PE=4 SV=1) HSP 1 Score: 649.432 bits (1674), Expect = 0.000e+0 Identity = 636/2509 (25.35%), Postives = 1105/2509 (44.04%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCI-------------------FNTHLSKTKVEDINKNMPIYIEATKLLLSECKV--------AIEKINSEV-TKDSLKFKDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILV-NIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFE------------------------NPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT-SANLFDK-----------------EILLENEKRNFQIFFSKLKQIGGAPIILPKE---NEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKY-----------------------RTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIK-------------------------------MRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYL--------KIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYL----ARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRS----CIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKN----YLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEK----KQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMII----TKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFR----KHYIRQQYNETRKKVIFIQ------------------------------------SLIRQFIAIQK--------------YKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLL----AATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFI--------CQK-------------------NAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKL---------------------------RSSSIIVQKIFRGFNAHKKFLKLKN-ASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLL----AAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYL----IRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTH----------RKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISK----FKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMK---------------------------QSITVIQKNCRKFIARKRFLEIKSNIIIIQK----------------------FFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKL--------KNASIIISKHVRGVLVRNHFQKNK-----------QHM----------KIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKR--SAVVIQR-----------------------IWRGRQLRCHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGK-----AGVLNFDVIGSEFIKLVKNLLYRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSIS 6879
D+ WL++QE F W+N + FN + TK E K +L + C++ AI+++ EV K L KD +K + L +++YN WL + ++ F + L SN++ F+ ++LWN DIA + R + + + +L+R L++ L +V LD AK++ + D LF D+ K + ++L F FL GEG + + + L VSH+QT + E+ F V NL+ D+ G+RL R+ ++ + + SKLR PA+ +K N+++A++ K+ G ++ G ID I GHREKTL LLW ++ ++ ++D +L EI + +P LL+ WV +VC YN+ N++ + DGR C LIH+Y P YL I+ TT T +L K E LLENEK NFQ+ + +GG P ++ E N IP+ + + L+F +RL+DL RAA IQ WR+Y R+F + K H + +Q+ R F K+ + +K +I Q+ + +LAR +I++ +A+ IQ YR C+ +Y IKS + +Q+ FR NYL K ++S ++IQ+ R L R +R+R+S IIQ++ + L R++++++ A V +Q+AFRG+ R + +AA++IQ+ YR V +R +L+L++SV+I+Q+ +F KL K ++ + Q RG R+ + +++ ++ Y+ ++QF+ ++++ +++Q+ + + + +F+A K A +IQ+ R + R + AA +IQK R + RK+FL Q +A++IQ++ R+ I +++ Y++++Q+ + +Q +G V++ KK + Q+ R Y + Y+ + + IIIQ+ +RA R +L + + +Q + + R+ K++ TIQ R QR +Y + K A IQR+FR+ + K KQ +AA +Q ++ +++ K + T+IQ Y R +CRK+F + I++Q R I + Y + AT+++ +G R++ + + VIQ FR + R +L+ K +AI+IQ+ R + R Y TAI IQ RG VR+ L +AT IQ +R + R + ++ AA VIQ++FR K+ + +QY +K + IQ +L + I IQ+ Y+ M+KAA +Q +G +R+++ + +A +IQ R Y R +FQ + + +++Q+ R L R ++ L +A +IQ + RG R+ I A +IQ Y A+ R F+ CQ+ NA I +Q RG +R+ R I +QS + I+++ YQKL + +++++Q FRG A ++ LKLK+ A+I +Q R +C Y + A+I IQ+ R L K ++ L AAI LQ HFR + R I + +AA +IQ +R + + + S + +Q ++++++ R+KYL +R+ I IQ R Y R + + IIQ V R + R K+ KA +Q R + + + + A ++IQ +R + R ++ + R V IQ + R + K FK ++ ATL +Q +RG+F R + K V IQ +R ++ R+ ++ ++ + +Q+FYRMH + Y + +S+ +Q + R FI +RF ++K++ + IQ +FR A+R + + I F+ +R +L + +Y+ +R +KT+ R + ++KS + +Q RG+ +RK K+ A++ I RG L R H+ +A + +K++ + + IQ +FR + ++RY + +++Q+ + + R +A VIQR +WRG R + KKI IS IR+R + NR + + + AL+ L + A +L L LE T LS E C+ L+ES A + L+ CNR V +E+++ V NL K V + L++ +YR K KG +IF C LLV+L++ +++++
Sbjct: 266 DERWLEKQERGFTWWMNYVLTPDDFKVTTEVAKGVLSKFNIPKAPTKEEMSFKTYTARRRLNRLRRAACQLFTSDSMVKAIQRLELEVEAKRLLVRKDRHLWKDIGERQKLLNWLLSYNPLWL----RIGLETIFGELIPLESNSDVMGLAMFVLGRLLWNPDIATEFRHPKVPHLYRDGHDEALSRFTLKKLLLLVCFLDKAKESRLIEHDPCLFCMDAEFKQTKDLLLAFARDFLSGEGILSRHLNLLGLPVSHVQTPLAEFSFAVQNLAVDLRCGIRLVRIMELFTQDWSLSSKLRMPAISRLQKVHNVDIALQVLKEKGVSLKDEHGTVIDSRDIVDGHREKTLNLLWKIIFTFQVEVLLDEVQLKDEISFLKKTWRTKQKLALLKADKCAVMSSKGSPRFEQPTEKLTLLMDWVNAVCDFYNLKAENLTVSFSDGRVLCYLIHHYHPNYLVAESIHQKTTQTIECDLRGKVELNNSSSDSDCSFDSLEQLLENEKSNFQLVNKAVSYLGGVPAMISPEDMSNTIPNEKVVTCYLSFLCARLLDLRNETRAARVIQSAWRRYKLQKDIQLNQQRNLAACKIQALVRSF-IQKRRVKRHNRAATTIQAFWRGFSAQKELRRLKEAKHFAIQNRAAVLIQKTYRGWRTRTFLKKNHACVIIQTAFRNWLAR-KIARRNAAALRIQTWYRMQRCQRQYMAIKSVAICIQAWFR-----GNYLRRRFQTLKKQHQSAVVIQSAFRASLVRKQIRRMRQSAVIIQRWYQACLQRNAERRRYLEIKSATVTLQAAFRGWKARTEMAQRHQAALMIQTAYRRFVAQRFFLSLKRSVVIVQQRYRAKVFGDKLRKEYQTLKHAAVKAQALWRGRAERKRINQLHQCATVIQSHYRRYVMQRQFVALKHAALVIQRRYKAFRVGKKI-------------------QSDFLAMKKAVTVIQSAYRGMKSRCELVKKHKAATLIQKFTRAFMCRKEFLAQKCAAVIIQQHYRAHILRRSERDCYVQLRQATVSLQAIYRGSRVRRELKKKQQAATVIQACFRMYKARMSYMATKCAAIIIQQRYRAHVYGKRTRASYLRMKTAIVTIQSGFRGMKVRRDLQKMRLAATTIQARFRGHSQRVKYRRQKWAACVIQRRFRAVQMKNAVEKQYTAMKKAALCIQSAYRGMRTRRELFKKHTAATLIQTYVRAFLCRKKFLAQKSAAIIIQQHYRAHILRCSERDCYVQLRQATVSLQAIYRGSRVRRELKKKQQAATVIQACFRMYKARMSYLATKCAAIIIQQRYRAHVYAKRTRASYLRMKTAIVTIQSGFRGMKVRRDLQKMRLAATTIQARFRGHSQRVKYRRQKWAAYVIQRRFRANKMKNAVEKQYTAMKKAALCIQSAYRGIRTRKQIAEMHMAARVIQQRYRVYKQYNNYQTLKQATIIIQRKYRVKLLGKHQRERYRTMQKAAISLQAAYRGMSVRREFQKRHEAATVIQAWYRMYRVRMAFQAMRLAAVLVQRQYRCHLKRKEARKSFLKLRHSAVVIQSVFRGNRTRREIAKLHSAAAVIQRRYMAYKERKSFLSIKTTVELCQRKWRAVLAARRERKVYLAKHNAVIAIQAACRGIKVRRQMRMEREAAITIQSHFRKLISKRYYQKLLWATRTVQQRFRARKLMKQDVESFKEKKRAAVVLQAAFRGMKA-RQALKLKHQAAIVLQSAYRAHCAQTRYLCMKYAAIAIQQRYRSMLAARKQRQDFLKLRYAAISLQAHFRGQKVRREIIQKHQAAMLIQASFRKHREVTKYQAMRLSAIILQRHYRSFVEAKVDREKYLMVRKSVILIQAAFRGYTVRRTVAEMNKAATIIQAVFRMHKQRSAFKRQGKQARDLTKRIKAARTVQSYLRMSIQRRRYLKTRAAIVLIQSAYRRHCCRIQYARMRNCAVLIQQWYRSCKLVQKQRNDFKAVQKATLTLQCALRGMFSR-RLAKRRHAAVKIQSVLRMHVHRSCYVKLRSCTVMLQAFYRMHTARRTYLRWQTAAVAVQTFYRAYRAKLEQRQRYLRTLESVRTLQAHVRGFIEYRRFQKMKASAVTIQAGFHAYQTRKLRGQTLAALKIQAWFRGCQARRDFISKQTAIAFIHRCLRTRLQRARYRSVRVIQRRWRKTLIARKQRADFLTIRKSAVDIQALWRGYRVRKSLQKVIKEHRRRRNAAAVTIQAFCRGWLTRQQEAARAVRRQRFIAAAYHHLCAVRIQRALRAHWALKAAKKQISSVVYIQRWFRAKLHRKRYLEQRQKIIMVQRAVKVWLGYRNQAATVIQRAAKCFLLRRRKERQRQGVIKLLALWRGHCSRKLHDTKKI---IS-IRHRLRKVNREAKEEDKLCNKTATALSYLLGYQ-NYAYILAALKHLETATRLSPECCEHLVESGATHTIFTLIRSCNRSVPSMEIITLATQVLLNLSKYNKTIEAVYEVPDSVDTLLDLLQ--IYREKAGDKVADKGGSIFTKACFLLVILVQDQERAMG 2735
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Cavefish
Match: ENSAMXT00000036226.1 (pep primary_assembly:Astyanax_mexicanus-2.0:5:19209457:19235971:1 gene:ENSAMXG00000030872.1 transcript:ENSAMXT00000036226.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 263.462 bits (672), Expect = 1.308e-70 Identity = 302/1204 (25.08%), Postives = 536/1204 (44.52%), Query Frame = 1
Query: 3610 NQAATVVQKYFKSYICKKQFRKMKESVTVIQK-YQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFI----KRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNE----TRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLL----AAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLI----RKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYIL----RKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMH----YEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSN----------------IIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLK-------YQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQR---------------------------FIRGFLIR------KIFLKLKNA-SIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQR----W----------------RFIV------LKRSAVVIQRIWRGRQLR-CHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSEFIKLVKNLL-----YRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSI 6876
N+ V ++++++Y + ++R +K++ +IQ+ Y+ +L+ ++Q +K + QK A +T+ +G ARK+ + + +IQ +R + R + ++K IVIQ R + +R+ YCS A +Q RG VRK ++AT++Q +YR Y+++ F R AA+++Q+++R H R++ E R I +Q++ R ++ + AAT IQ+ Y RKK+++ R + V Q+ R L+ + Y K AA IQ RG VR+R+ +E+KA IQ R H + ++ A +Q+ R +MK + K ++ R +++++Q FRG A + A+I IQ R +C Y R A++ IQ+ R L K + L A+I LQ FR R I L+ +AA++IQ +R + R + + S + IQ +F+AY++ R++YL +R+ I IQ L R Y R+ ++ + IQ R + HR K++ A++ IQ +R + ++ ++++IQ+ +R L R EFK+ +K + +Q +RR + + + + A + IQ + R +Y K+ V +Q R +R +L + + + +Q+FYR + + + Y +++ +Q + R FI +RF ++K + IQ +FR A+R Y + + + ++ K + + QK R A +LIQ T +GY R+ +K + S + +QR F RG+L R + L LK+ + H+ V ++ + + +A + +K++ + I +Q +F+ Q++RY L + ++ QR W RF++ LK+ + +Q +WRG R H K I +R+RF + N + + + AL+ L + A +L L LE T LS E C+ L+ S A + + L+ CNR V +E+++ I V NL K D + E V LL YR K KG +IF C LLV+L++ E+++I
Sbjct: 170 NKTFHVSRQHYRAYKQRNEYRALKQATFLIQRRYRAKLLAKQQREKYCSM-----------------QK---AAITLQAAYRGMQARKRIAEMQLAAKIIQRKYRAYKQRNEYCALKQVTIVIQGRYRAKLLAKQQRQRYCSMQKAAITLQAAYRGMRVRKEAQKRQEAATVLQAWYRMYRVKMAFQAMRLAAVLVQRRYRCHLERKEARERFVKLRHSAIVVQAVFRGNRTRREIGNLHSAATVIQRKYLAYKERKKFLSVRDTVVHCQQKWRAVLASRQQL-------------------KAYLAKRSAAIAIQAAFRGMKVRRRVQIERKAAITIQAHVRMHKTKVYYQRLLWATKTVQRRYRA-----------------NQMMKEEM--KSLKQKRMATVVLQAAFRGMKARHTLKQKHKAAIVIQSAYRAHCAQTRYLCMRYAAVAIQQRYRATLAARKQREHFLQLRCASISLQACFRGQRARREIGLQHQAAKVIQASFRSHRERTKYQAMRVSAMIIQRHFRAYIVAKDNRERYLSLRKSAILIQTLFRGYSVRHHIAKMHKAATTIQAALRMH-KHRSAFKRQSAIVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKHRDEFKRIQKATLTLQRALRRMVAM-RLATRRRAAIKIQSVLHMHVHRRRYLKLRSCAVMLQAQYRMCTMRRAYLKKQTAAVTVQTFYRAYRAKVEQRECYLRTLRNVRTLQAHVRGFIQHRRFQQMKEAGFRAYKTRKLAAQTRAALKIQAWFRGHQARRDYISKQTAVATIHRCLQTKFQRARCSVVRRSIQKERNAAVLIQSTFRGYRQRQAFKQKKASALLIQRRFRAVQLAKAEKERRRRRNAAAVTIQAFCRGWLTRQKVRFMRFGLTLKHRFTAAAYHHLCAVRIQRALRTH------WALKAAKKQISSVIYVQRWFKAKFQRKRY-LEQRQKIITAQRAVKAWLNHRNQAATVIQHAAKRFLLRRKKERLKQGILKVQALWRGHCSRKLHDTTKVIS-----MRHRFRKVNSEAKEEDKLCNKTATALSYLLGYQ-NYAYILAALKHLETATRLSPECCERLVNSGATRTIFTLIRSCNRSVPSMEIITLAIQVLLNLSKYNK-TIDAV-YEVPDSVDTLLDLLQIYREKAGDKVADKGGSIFTKACFLLVILVQDERRAI 1298 HSP 2 Score: 189.119 bits (479), Expect = 1.612e-47 Identity = 241/987 (24.42%), Postives = 436/987 (44.17%), Query Frame = 1
Query: 2143 KKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKN----YLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGY---------------------------LARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRK-----LEKRLRSCIIIQKYIRGF-INRRNFLKFKSAVNILEH--------YFMGYL----------RRKQFLKM--------RNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALI----QRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLIC----------------------RKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFA----RKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKF----------------SAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNI-------RGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNE--------------------TRKKVIF-----------------------IQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIR 4626
+K+ S++ I Q+ + AR RI++M+ +A +IQ+ YR Y R Y +K T+V+Q +R L+ K Y + ++ + +Q RG R ++ +++ ++Q + + Y AR++FVKL + +V+Q+ FRG RR AA +IQ Y + R+ +L++R +V+ Q+ VL R+ L KR + I IQ RG + RR ++ K+A+ I H Y+ L R Q +K R + ++LQ R + R++ K K+AI+IQ +++ + A+ ++ + A + IQ + RA + QR F LR A+I +Q FR R++ +Q+ +A VIQ + RS + Y ++ S ++IQ+H + ++V K +++YL +RKS I+IQ FR S R K +Q ++MH+ R F K +S ++ IQ R R +Y + +K+ + IQ+ +RS K +VQK+ + +F++++++ +Q+ RR++ R+++ K ++LQ++ RM ++ Y KK A +T+ F + Y A R+ YL +V +Q R F+ + F +K +A+ IQ + RG R+ Y S+ TA+ I + + R +VR+++ +A LIQ +R Y+ R+ F K+ +A++IQ++FR + + E TR+KV F IQ +R A++ K+ + Y+Q+ K RK+Y+ QR+ + Q+ V+ +L+ ++ AAT+IQ A+ +L+R++ ++ + +Q +R H R
Sbjct: 214 EKYCSMQKAAITLQAAYRGMQARKRIAEMQLAAKIIQRKYRAYKQRNEYCALKQVTIVIQGRYRAKLLAKQQRQRYCSMQKAAITLQAAYRGMRVRKEAQKRQEAATVLQAWYRMYRVKMAFQAMRLAAVLVQRRYRCHLERKEARERFVKLRHSAIVVQAVFRGNRTRREIGNLHSAATVIQRKYLAYKERKKFLSVRDTVVHCQQKWRAVLASRQQLKAYLAKR-SAAIAIQAAFRGMKVRRRVQIERKAAITIQAHVRMHKTKVYYQRLLWATKTVQRRYRANQMMKEEMKSLKQKRMATVVLQAAFRGMKARHTLKQKHKAAIVIQSAYRAHCAQTRYLCMRYAAVAIQQRYRATLAARKQREHFLQLRCASISLQACFRGQRARREIGLQHQAAKVIQASFRSHRERTKYQAMRVSAMIIQRHFRAYIVAKDN-------------------RERYLSLRKSAILIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAF-KRQSAIVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRK-------------LVQKH------RDEFKRIQKATLTLQRALRRMVAMRLATRRRAAIKIQSVLHMHVHRRRYLKLRSCAVMLQAQYRMCTMRRAYLKKQTAAVTVQTFYRAYRAKVEQRECYLRTLRNVRTLQAHVRGFIQHRRFQQMKEAGFRAYKTRKLAAQTRAALKIQAWFRGHQARRDYISKQTAVATIHRCLQTKFQRARCSVVRRSIQKERNAAVLIQSTFRGYRQRQAFKQKKASALLIQRRFRAVQLAKAEKERRRRRNAAAVTIQAFCRGWLTRQKVRFMRFGLTLKHRFTAAAYHHLCAVRIQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRYLEQRQKIITAQRAVKAWLNHRNQ----------------------------AATVIQHAAKRFLLRRKKERLKQGILKVQALWRGHCSR 1132 HSP 3 Score: 188.734 bits (478), Expect = 1.847e-47 Identity = 236/1019 (23.16%), Postives = 452/1019 (44.36%), Query Frame = 1
Query: 2254 KNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKN----YLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGY------------------------LA---RKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRL----RSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLR-MLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLK-IKQ---SVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRA-ISARKQ---FLNFRKFTI-----------------------VVQKYIKMHQCRQKFLKLKSQVITIQKNIRALL----QRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAAT----------------------VVQKYFKSYICKKQFRKMKESVTVIQKY--QRRLI--CRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGF----IKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQ------------SLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRA-----------HTIRSHFIC-----QKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTR 4923
++YR Y R Y +K AT ++Q +R L+ K Y + ++ + +Q RG R ++ + KIIQ+ + Y LA R+++ + KA + +Q+A+RG R+ + +AA ++Q++YR + + +R + +++Q+ L +++ +R S I++Q RG RR SA +++ ++ Y RK+FL +R++V+ Q+ R +L+ R K ++AK+SA I IQ R + RR+ Q R AAI IQ R + + + ++ +Q+ R+ K +K +KQ + +V+Q +G + + K+ I+ QS R + Q +YL +R + + IQ+ +RA ++ARKQ FL R +I V+Q + H+ R K+ ++ + IQ++ RA + R RY+ +K+ I IQ FR + I ++AAT ++Q ++ + C+ Q+ +M++S +IQ++ R+L+ R +F++ K + LQ +R ++ + ++ AA + I + + R++YL R +++Q +R R+ +L + +A+ +Q + R + +R+ Y ++ +Q ++RGF+ H + + + +R+YK RK + AA+ IQ FR H R+ Y + V I S++R+ I ++ + AA IQ +GY R+ + ++ SA++IQ+ R K + +R+ AA IQ RG+L R+++ + + + F A +R+H+ Q ++ I +Q+ + RK + E R KII Q +K ++ + ++ ++Q + F +K +LK + +Q R +C KL+ T+
Sbjct: 178 QHYRAYKQRNEYRALKQATFLIQRRYRAKLLAKQQREKYCSMQKAAITLQAAYRGMQARKRIAEMQLAAKIIQRKYRAYKQRNEYCALKQVTIVIQGRYRAKLLAKQQRQRYCSMQKAAITLQAAYRGMRVRKEAQKRQEAATVLQAWYRMYRVKMAFQAMRLAAVLVQRRYRCHLERKEARERFVKLRHSAIVVQAVFRGNRTRREIGNLHSAATVIQRKYLAYKERKKFLSVRDTVVHCQQKWRAVLASRQQL--------------------KAYLAKRSAAIAIQAAFRGMKVRRRVQIERKAAITIQAHVRMHKTKVYYQRLLWATKTVQRRYRANQMMKEEMKSLKQKRMATVVLQAAFRGMKARHTLKQKHKAAIVIQSAYRAHCAQTRYLCMRYAAVAIQQRYRATLAARKQREHFLQLRCASISLQACFRGQRARREIGLQHQAAKVIQASFRSHRERTKYQAMRVSAMIIQRHFRAYIVAKDNRERYLSLRKSAILIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAFKRQSAIVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKHRDEFKRIQKATLTLQRALRRMVAMRLATRRRAA-IKIQSVLHMHVHRRRYLKLRSCAVMLQAQYRMCTMRRAYLKKQTAAVTVQTFYRAYRAKVEQRECYLRTLRNVRTLQAHVRGFI------QHRRFQQMKEAGFRAYKTRK-LAAQTRAALKIQAWFRGHQARRDYISKQTAVATIHRCLQTKFQRARCSVVRRSI-----QKERNAAVLIQSTFRGYRQRQAFKQKKASALLIQRRFRAVQLAK-------------------AEKERRRRRNAAAVTIQAFCRGWLTRQKVRFMRFGLTLKHRFTAAAYHHLCAVRIQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRYLEQRQKIITAQRAVKAWLNHR-----NQAATVIQHAAKRFLLRRKKERLKQGILKVQALWRGHCSRKLHDTTK 1139
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Cavefish
Match: ENSAMXT00000040686.1 (pep primary_assembly:Astyanax_mexicanus-2.0:5:19214723:19233704:1 gene:ENSAMXG00000030872.1 transcript:ENSAMXT00000040686.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 193.741 bits (491), Expect = 3.269e-49 Identity = 219/889 (24.63%), Postives = 385/889 (43.31%), Query Frame = 1
Query: 745 AIEKINSEV-TKDSLKFKDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFN--VSLLSNNEAC-FKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKS----SAEMLTEFTSYFLKGE------GNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKILVNIDIMSKLRYPAVDLARK---TFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFENPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT----------------------------SANLFDKEILLENEKRNFQIFFSKLKQIGGAPIILPKE---NEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYR----------------------TFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKM---------RIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLV----QKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRS----------CII-IQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLR-MLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRK 3111
AI+++ EV K L KD +K + + +++YN WL + ++ F + L SN++ FI ++LWN DIA + R + + +L+R L++ L +V LD AK++ + D LF D+ K + + EFT++F +GE IL + + ++ I EYD + + + G RL +I V I+ R ++L K TF +E+ + V + EEI + W ++K L W + DK + + +P + + LLL WV +VC Y++ N + + DGR C LIH+Y P +L +I+ TT T + D ++LLENE+ NFQ+ + + +GG P ++ E N IP+ + + L+F +RL+DL RAA IQ WR+Y+ +L K + ++Q+ R + K+ K +K ++ Q++ + Y RH I+KM K+A IQ R + R +++ A VLQ FR + ++ YL++ + + +Q + RG R + R+ K+ IQ Y++ + R++F+K A+V+IQSA+RG+ R Y K+AV+IQ +YRS R + ++K+ + +Q+ + +++ K R C + IQ+ +R + K S+V ++ +F +RK++L+ R +I Q+ ++ L+ RN A +IQ + + RRK + L+ + +Q +R + RK
Sbjct: 31 AIQRLELEVEAKRLLVRKDRHLWKDIGERQKVLNWLLSYNPLWL----RIGLETIFGELIPLESNSDVMGLAMFILGRLLWNPDIAAEFRHPKVPHLYRDGHEEALSRFTLKKLLLLVCFLDKAKESRLIEHDPCLFCMDAEYKVLTYLNYLLSAEFTAFFTEGEKLKSTRDQILLGLTVYIYMNVYMNVCI-EYDIILQSYVYTLFCG----RLIRIFVY--IVDGHREKTLNLLWKIIFTFQVEVLLD---------VEHLKEEISFLKKTWRTKQK---LAW-----------LKADKCAVK-RSNGSPRAEQSSEKLTLLLDWVNAVCEFYSLKAENFTVSFSDGRILCYLIHHYHPNHLNAEKIHQKTTQTIECDQRGKVELNSSSSDSDCSFDSLEQNGSPAVDFKVLLENERSNFQLVNTAVSYLGGVPAMISPEDMSNTIPNEKVVTCYLSFLCARLLDLRNETRAARVIQSAWRRYKLQKDIQLNKQRNMAACKIQAVVKSFLQKRRLKRRNRAATVIQAFWRGYSAQKELKRMKEAKRYTTQNRAAVLIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAFKRQCWAAGVLQERFRAWKCGHQQRQRYLQLKDAAICMQKSFRGKQAR-DLVRLIKAASTIQSYLRMSIQRRQFMKTKAAVVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKHRDEFKRIQKATLTLQRALRRMVVKETANALRRQRFTAAAYHHLCAVRIQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRYLEQRQKIITAQRAVKAWLNHRN-----------------------------QAATVIQHAAKRFLLRRKKERLKQGILKVQALWRGHCSRK 854 HSP 2 Score: 174.866 bits (442), Expect = 2.582e-43 Identity = 168/695 (24.17%), Postives = 300/695 (43.17%), Query Frame = 1
Query: 1516 GHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLFE------------------------NPIXXXXXXXXXXXXVWVKSVCGLYNINVSNIS-NLKDGRGFCLLIHYYLPEYLKLNEINHNTTLT----------------------------SANLFDKEILLENEKRNFQIFFSKLKQIGGAPIILPKE---NEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYRTFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVC----RRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALI--------QRRKF---QYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARK 3387
GHREKTL LLW ++ ++ ++D + L EI + +P + + LLL WV +VC Y++ N + + DGR C LIH+Y P +L +I+ TT T + D ++LLENE+ NFQ+ + + +GG P ++ E N IP+ + + L+F +RL+DL RAA IQ WR+Y+ +++ + L K ++ M Q+VVK +L + R+ + ++A +IQ +R Y + +++K A +RY Q ++ +IQ +GY R K+ KA IQ+A R + R + Q AA ++Q +R+ C R+ YL L+ + I +QK + R L + +++ IQ Y+R I RR F+K K+AV +++ + G+ R Q+ +M+ S +L+Q+ R L + EF + AT+ +Q +R ++ +R++F Y A+ IQ+ R + K Q S I +Q+ ++ +K YL+ +Q ++ Q+ K +L + Q +++LL+++ ++++ + +Q +R +RK
Sbjct: 246 GHREKTLNLLWKIIFTFQVEVLLDVEHLKEEISFLKKTWRTKQKLAWLKADKCAVKRSNGSPRAEQSSEKLTLLLDWVNAVCEFYSLKAENFTVSFSDGRILCYLIHHYHPNHLNAEKIHQKTTQTIECDQRGKVELNSSSSDSDCSFDSLEQNGSPAVDFKVLLENERSNFQLVNTAVSYLGGVPAMISPEDMSNTIPNEKVVTCYLSFLCARLLDLRNETRAARVIQSAWRRYK----------------------LQKDIQLNKQRN--MAACKIQAVVKSFLQKRRLKRRNRAATVIQAFWRGYSAQKELKRMKEA--------KRYTTQN-----------------------------RAAVLIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAFKRQCWAAGVLQERFRAWKCGHQQRQRYLQLKDAAICMQKSF-RGKQARDLVRLIKAASTIQSYLRMSIQRRQFMKTKAAVVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKH-------------------RDEFKRIQKATLTLQRALRRMVVKETANALRRQRFTAAAYHHLCAVRIQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRYLEQRQKIITAQRAVKAWL-----NHRNQAATVIQHAAKRFLLRRKKERLKQGILKVQALWRGHCSRK 854 HSP 3 Score: 126.716 bits (317), Expect = 1.859e-28 Identity = 146/572 (25.52%), Postives = 257/572 (44.93%), Query Frame = 1
Query: 5377 SELKTFQNLKNASIIIQKNFRCYILRKEF---KKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKII---------KLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIA----RKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLV--------RNHFQKNKQH----MKI-------FAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQR----W----------------RFIV------LKRSAVVIQRIWRGRQLR-CHLNAKKIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSEFIKLVKNLL-----YRN-INSKRGTKGITIFCHTCLLLVLLIKMEQKSI 6876
+ L +N A+ +IQ +R Y L+K+ K++ KIQ+ ++ ++ + K A +IQ RG + + K++ + V IQ R VR + K+ IQ+ RMH ++ + V+Q+ R + R+R+L++K I +QK FR A R R + +QS +R + + ++ K + A +LIQ +G++ R Y +QKS + +Q++ R + R F +++ A++ + + +R ++V R F H ++I +A + +K++ + I +Q +F+ Q++RY L + ++ QR W RF++ LK+ + +Q +WRG R H K I +R+RF + N + + + AL+ L + A +L L LE T LS E C+ L+ S A + + L+ CNR V +E+++ I V NL K D + E V LL YR K KG +IF C LLV+L++ E+++I
Sbjct: 458 ARLLDLRNETRAARVIQSAWRRYKLQKDIQLNKQRNMAACKIQAVVKSFLQKRRLKRRNRAATVIQAFWRGYSAQKELKRMKEAKRYTTQNRAAVLIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAFKRQCWAAGVLQERFRAWKCGHQQRQRYLQLKDAAICMQKSFRGKQA-RDLVRLIKAASTIQSYLRMSIQRRQFMKTKAAVVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKHRDEFKRIQKATLTLQRALRRMVVKETANALRRQRFTAAAYHHLCAVRIQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRY-LEQRQKIITAQRAVKAWLNHRNQAATVIQHAAKRFLLRRKKERLKQGILKVQALWRGHCSRKLHDTTKVIS-----MRHRFRKVNSEAKEEDKLCNKTATALSYLLGYQ-NYAYILAALKHLETATRLSPECCERLVNSGATRTIFTLIRSCNRSVPSMEIITLAIQVLLNLSKYNK-TIDAV-YEVPDSVDTLLDLLQIYREKAGDKVADKGGSIFTKACFLLVILVQDERRAI 1019 HSP 4 Score: 105.916 bits (263), Expect = 3.749e-22 Identity = 133/493 (26.98%), Postives = 214/493 (43.41%), Query Frame = 1
Query: 4222 NETRKKVIFIQSLIRQFI---AIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLE----QKAARIIQNFYRGYTIRA---------------HFLC-------------------QKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYIS-RNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQ---SYIRRY----ICISKFKMIKSAT 5553
NETR + IQS R++ IQ KQ AA IQ + K ++ +++ + R+A +IQ R Y QK ++R Y + AA LIQ + RGY VR I KA IQ R H RS F Q AA LQ+ R + G R+ Y +L+ ++I +QK FRG A + ++L A+ IQ +R Q + + T+ A ++IQ RG CR++Y R +A+++Q+ +R ++++ E QKA +Q R ++ H LC Q +S + +Q +FKA RK+YLE RQK I Q V+ +++ RN+ + +IQ + + RK + K+ ++ +Q +R K L + + +I R + E K++ K C K SY+ Y ++ K +++AT
Sbjct: 465 NETRAARV-IQSAWRRYKLQKDIQLNKQRNMAACKIQAVVKSFLQKRRLKRRNRAATVIQAFWRGY--------------SAQKELKRMKEAKRYTTQNRAAVLIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAFKRQCWAAGVLQERFRAWKC-------------------GHQQRQRYLQLKDAAICMQKSFRGKQA-RDLVRLIKAASTIQSYLRMSIQRRQFMKTKAAVVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKHRDEFKRIQKATLTLQRALRRMVVKETANALRRQRFTAAAYHHLCAVRIQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRYLEQRQKIITAQRAVKAWLNHRNQ------AATVIQHAAKRFLLRRKKERLKQGILKVQALWRGHCSRK----LHDTTKVISMRHRFRKVNSEAKEEDKLCNKTATALSYLLGYQNYAYILAALKHLETAT 912 HSP 5 Score: 102.064 bits (253), Expect = 5.394e-21 Identity = 107/418 (25.60%), Postives = 197/418 (47.13%), Query Frame = 1
Query: 3055 LRN---AAIIIQKTFRCYSVRKKFLI---QYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRAL----LQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQS--KIRMIITKKRYQ-KKIA-ATLTISKFVK--------GYFARKKYL--SYRHSVIV-IQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETR 4233
LRN AA +IQ +R Y ++K + + +A IQ V+S + ++ + ++ VIQ +G+ Q +++ K+Y ++ ++IQ FR S R K +Q ++MH+ R F + +Q+ RA QR+RY++ K A I +Q+ FR K+ + ++ +AA+ +Q Y + I ++QF K K +V +IQ R CR Q+ + K +L+Q + R ++ K R + K+I ATLT+ + ++ R+++ +Y H V IQ + R K S I +Q++ + +RK Y Q I Q+ ++ + LN +Q+AT+IQH + + +R+ + + +Q +R H R+ ++ T+
Sbjct: 463 LRNETRAARVIQSAWRRYKLQKDIQLNKQRNMAACKIQAVVKSFLQKRRLKRRNRAATVIQAFWRGY--------------SAQKELKRMKEAKRYTTQNRAAVLIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAFKRQCWAAGVLQERFRAWKCGHQQRQRYLQLKDAAICMQKSFRG-KQARDLVRLIKAASTIQSYLRMSIQRRQFMKTKAAVVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKHRDEFKRIQKATLTLQRALRRMVVKETANALRRQRFTAAAYHHLCAVRIQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRYLEQRQKIITAQRAVKAW-----LNHRNQAATVIQHAAKRFLLRRKKERLKQGILKVQALWRGHCSRKLHDTTK 860 HSP 6 Score: 100.908 bits (250), Expect = 1.226e-20 Identity = 99/441 (22.45%), Postives = 201/441 (45.58%), Query Frame = 1
Query: 4573 EQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIIL-VQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKN---------ASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELK----TFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFR 5853
E +A R+IQ+ +R + KLQK+I+ + RN +Q+++K F+ ++ ++ ++ ++Q +RG++A K+ ++K A++ IQ R Y A+ IQ +R R ++RQ AA +LQ FR + G+ R +L K++ + +Q F+ R I+ + IQ +R I R +F++ K +V++IQ RG++ +Y + +K+ + IQ+ +R ++ F+ ++ A++ +Q+ R ++++ R+ +Y ++C + IQ+ +R + KK I V+++Q+ +A R R+L ++ II Q + ++N Q+ TVIQ ++F+ R++ +K I+ +Q +R
Sbjct: 466 ETRAARVIQSAWRRY--------------KLQKDIQ-------LNKQRNMAACKIQAVVKSFLQKRRLKRRNRAATVIQAFWRGYSAQKELKRMKEAKRYTTQNRAAVLIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAFKRQCWAAGVLQERFRAWKC-------------------GHQQRQRYLQLKDAAICMQKSFRGKQARDLVRLIKAAST-IQSYLRMSIQRRQFMKTKAAVVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKHRDEFKRIQKATLTLQRALRRMVVKETANALRRQRFTAAAY--HHLCAVR----------IQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRYLEQRQKIITAQRAVKAWLNHRN-----QAATVIQHAAKRFLLRRKKERLKQGILKVQALWR 848 HSP 7 Score: 92.4337 bits (228), Expect = 4.533e-18 Identity = 100/415 (24.10%), Postives = 178/415 (42.89%), Query Frame = 1
Query: 3544 KAVIFIQRKFRSCKEKKQIILN---NQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQR---------RLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVK---------------------------GYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKI----RKNFICKRNAAIVIQKQFRKHYIRQQYNETRKK-----------VIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIR 4626
+A IQ +R K +K I LN N AA +Q KS++ K++ ++ + TVIQ + R R+ K++ + + +L+Q+ R + K A TI ++ G+ R++YL + + I +Q SFR R + IK +A IQ YLR I+R+ + A+ +IQ RG R +SA LIQ +YRS K+ R F + A + +Q+ R+ +++ N R++ + IQ +R A++ K+ + Y+Q+ K RK+Y+ QR+ + Q+ V+ +L+ ++ AAT+IQ A+ +L+R++ ++ + +Q +R H R
Sbjct: 468 RAARVIQSAWRRYKLQKDIQLNKQRNMAACKIQAVVKSFLQKRRLKRRNRAATVIQAFWRGYSAQKELKRMKEAKRYTTQNRAAVLIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAFKRQCWAAGVLQERFRAWKCGHQQRQRYLQLKDAAICMQKSFRGKQARDLVRLIK-AASTIQSYLRMSIQRRQFMKTKAAVVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKHRDEFKRIQKATLTLQRALRRMVVKETANALRRQRFTAAAYHHLCAVRIQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRYLEQRQKIITAQRAVKAWLNHRNQ----------------------------AATVIQHAAKRFLLRRKKERLKQGILKVQALWRGHCSR 853 HSP 8 Score: 77.7962 bits (190), Expect = 1.307e-13 Identity = 87/344 (25.29%), Postives = 159/344 (46.22%), Query Frame = 1
Query: 4042 IQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKN---------FICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAK----GYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTI----RSHFICQKNAAIKLQKNIRGYLIRKNFTETRNK-----------IILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRN-ASIVIQKYVRGFLCRIKYQR 4986
IQ ++ FL ++ L +++AT+IQ F+R Y +K + + AA++IQ FR + +R + K IQ+ +R +K+ AA +Q+ + G+ R++Y+ + +A+ +QK+ R + + IQ Y+R + R + + A LIQ RG+ R + QK+ +IQ +YR+ + R F + A + LQ+ +R ++++ R + + +Q ++ A K +K SS I VQ+ F+ K++L+ + I Q+ V K + + RN A+ VIQ + FL R K +R
Sbjct: 499 IQAVVKSFLQKRRLKRRNRAATVIQAFWRGYSAQKELKRMKEAKRYTTQNRAAVLIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHRSAFKRQCWAAGVLQERFRAWKCGHQQRQRYLQLKDAAICMQKSFRGK-QARDLVRLIKAASTIQSYLRMSIQRRQFMKTKAAVVLIQSAYRGHYCRVQYARMQKSAVLIQQWYRSRKLVQKHRDEFKRIQKATLTLQRALRRMVVKETANALRRQRFTAAAYHHLCAVRIQRALRTHWALKAAKKQISSVIYVQRWFKAKFQRKRYLEQRQKIITAQRAV------KAWLNHRNQAATVIQHAAKRFLLRRKKER 835
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Cavefish
Match: myo5ab (myosin VAb [Source:ZFIN;Acc:ZDB-GENE-050411-72]) HSP 1 Score: 72.7886 bits (177), Expect = 4.986e-12 Identity = 69/239 (28.87%), Postives = 115/239 (48.12%), Query Frame = 1
Query: 2173 IICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK--KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLR--KSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQK 2877
+ CQ+V+++ + K K+ I + YL ++R +K+++A V +Q R Y+ +K YL R+R ST IQ+YV+G AR K ++ TKA VVIQ R A RR Y + AAV++Q R R Y LR + V+++Q+ V L + + + +++ + +Q +R + RR K K +EHY +K + M N ++ LQ+
Sbjct: 701 LTCQNVLQQLIQDPDKYKFGKTKIFFRAGQVAYLEKLRADKLRAACVQIQKTIRCYVARKKYL-----------------------RLRWSTITIQRYVRGQQARALCKSLRRTKAAVVIQKYQRMCAARRLYQRKQLAAVLLQRLLRGYAARLQYKQLRYEQKVVVVQRWVRGWLARVQYRRTMQAVVYLQCCVRRMLARRELKKLKIEARSVEHY------KKLNVGMENKIMQLQR 910 HSP 2 Score: 70.0922 bits (170), Expect = 3.882e-11 Identity = 54/172 (31.40%), Postives = 85/172 (49.42%), Query Frame = 1
Query: 4774 QKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTR--NASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHF--LCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSV 5277
KLR++ + +QK R + A KK+L+L+ ++I IQ+ VR L + R A++VIQKY R R YQR+ LAA++LQR RGY R + L + V +Q + + +L R +Y Q +++QC VRR ++R +LK+
Sbjct: 740 DKLRAACVQIQKTIRCYVARKKYLRLRWSTITIQRYVRGQQARALCKSLRRTKAAVVIQKYQRMCAARRLYQRKQLAAVLLQR-----------------------LLRGYAARLQYKQLRYEQKVVVVQRWVRGWLARVQYRRTMQAVVYLQCCVRRMLARRELKKLKIEA 888 HSP 3 Score: 60.4622 bits (145), Expect = 3.032e-8 Identity = 46/150 (30.67%), Postives = 79/150 (52.67%), Query Frame = 1
Query: 3886 RHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCS--QTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKR--NAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQ 4323
R + + IQ + RC++ RK +L +++S I IQ+Y+RG R + S +T A VIQK R R+ +A L+Q R Y R + R +V+Q+ R R QY T + V+++Q +R+ +A ++ K++K A ++
Sbjct: 743 RAACVQIQKTIRCYVARKKYLRLRWSTITIQRYVRGQQARALCKSLRRTKAAVVIQKYQRMCAARRLYQRKQLAAVLLQRLLRGYAARLQYKQLRYEQKVVVVQRWVRGWLARVQYRRTMQAVVYLQCCVRRMLARRELKKLKIEARSVE 892 HSP 4 Score: 60.4622 bits (145), Expect = 3.136e-8 Identity = 50/171 (29.24%), Postives = 86/171 (50.29%), Query Frame = 1
Query: 5590 RLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMR--TATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLK 6096
+L+ K+ V IQK IR + R ++L ++ S I IQ + R Q + K+ R+ A ++IQK+ R A+R YQR + +Q L+RG A+L+Y+++R +++Q+ V+G+ R Y+ ++V+ LQ +R L R+ KLK
Sbjct: 736 KLRADKLRAACVQIQKTIRCYVARKKYLRLRWSTITIQRYVR-----------GQQARALCKSLRRTKA----------AVVIQKYQRMCAARRLYQRKQLAAVLLQRLLRGYAARLQYKQLRYEQKVVVVQRWVRGWLARVQYRRTMQAVVYLQCCVRRMLARRELKKLK 885 HSP 5 Score: 58.5362 bits (140), Expect = 1.266e-7 Identity = 47/193 (24.35%), Postives = 101/193 (52.33%), Query Frame = 1
Query: 5164 AYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMI--KSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKN 5736
AYL + + ++R + IQ +R Y++R ++LRL+ S I IQ+ RG +Q +A+ K+ RR A+++IQK R R+ +++K+ V +Q +R Y ++K + + +++Q+ +RG R++Y++ ++ VV++Q +R + R +K +++ + +++ +N
Sbjct: 732 AYLEKLRADKLRAACVQIQKTIRCYVARKKYLRLRWSTITIQRYVRG--------QQARALC---KSLRR----------TKAAVVIQKYQRMCAARRLYQRKQLAAVLLQRLLRGYAARLQYKQLRYEQKVVVVQRWVRGWLARVQYRRTMQAVVYLQCCVRRMLARRELKKLKIEARSVEHYKKLNVGMEN 903 HSP 6 Score: 55.8398 bits (133), Expect = 7.593e-7 Identity = 43/150 (28.67%), Postives = 84/150 (56.00%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLR--SSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNAS--IVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNF 5088
A +++QK IR Y+ RK + R I +Q ++G AR + LR +++++QK R A + + + + A++ +Q+ +R Y Y+ R +V+Q++VRG+L R++Y+R + A + LQ R+ L R + + AR ++++
Sbjct: 745 ACVQIQKTIRCYVARKKYLRLRWSTITIQRYVRGQQARALCKSLRRTKAAVVIQKYQRMCAARRLYQRKQLAAVLLQRLLRGYAARLQYKQLRYEQKVVVVQRWVRGWLARVQYRRTMQAVVYLQCCVRRMLARRELKKLKIEARSVEHY 894 HSP 7 Score: 55.4546 bits (132), Expect = 1.063e-6 Identity = 40/147 (27.21%), Postives = 83/147 (56.46%), Query Frame = 1
Query: 3400 FRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRR--RYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKM--KESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQK-KIAA 3825
R + +QK I+ + R+K+L+L+ ITIQ+ +R R + ++ KA + IQ+ R C ++ AA ++Q+ + Y + Q++++ ++ V V+Q++ R + R Q+++ M+ V+ LQ +R ++ ++ +K KI A
Sbjct: 742 LRAACVQIQKTIRCYVARKKYLRLRWSTITIQRYVRGQQARALCKSLRRTKAAVVIQKYQRMCAARRLYQRKQLAAVLLQRLLRGYAARLQYKQLRYEQKVVVVQRWVRGWLARVQYRRTMQAVVYLQCCVRRMLARRELKKLKIEA 888
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Cavefish
Match: myo5b (myosin VB [Source:ZFIN;Acc:ZDB-GENE-031219-7]) HSP 1 Score: 69.707 bits (169), Expect = 5.409e-11 Identity = 51/159 (32.08%), Postives = 87/159 (54.72%), Query Frame = 1
Query: 2386 IQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRL---RSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMR 2853
IQ +RG+L R Y +IRKS ++Q+Y +GYLA + I + + A Y KAA+I Q YR RR YL +R++VI IQ + +F R+L + IIIQ+ +RG+++R+ FL+ ++A +++ + L ++Q +++
Sbjct: 680 IQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLA--PYFAWIYCIYLTEHA--------EYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFT-RGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKRQLKQLK 827 HSP 2 Score: 65.855 bits (159), Expect = 7.717e-10 Identity = 56/207 (27.05%), Postives = 103/207 (49.76%), Query Frame = 1
Query: 2128 RFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLC-------------RSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYT--IQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKL 2703
R L KK ++ + +C+++++ + + K+ I + YL ++R +K + A + +Q R +L ++ YLKI +S +++Q RGYL + Y R+ K+ I QK + R+ ++ + +A++ IQ+ RG RR Y + A+IIQ R + R+ +L R + I+IQ +VL KR+L
Sbjct: 617 RVLMTKKDMTVGDKKQVCRNLLESLIKDPDKFQFGKTKIFFRAGQVAYLEKLRADKFRFACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKRQL 823 HSP 3 Score: 65.0846 bits (157), Expect = 1.108e-9 Identity = 47/160 (29.38%), Postives = 87/160 (54.37%), Query Frame = 1
Query: 3130 YSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCR---QKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQI 3600
++ I IQK VR + ++ YLKI++S +++Q++ +G+L I C L +YL++ K+ +I QK +R + R+ +L R+ I +Q + + R Q+FL L + I IQ+ +R L R+++++ + A I IQ +R K+Q+
Sbjct: 675 FACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLA------PYFAWIYCIYLTE----HAEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFL-LHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKRQL 823 HSP 4 Score: 64.6994 bits (156), Expect = 1.462e-9 Identity = 51/175 (29.14%), Postives = 84/175 (48.00%), Query Frame = 1
Query: 2719 SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYL-------------RRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQ--YLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIK 3198
+CI IQK +RG++ RR +LK + + +L+ Y GYL ++L++ + ++ QK RM+ +R ++L + A I IQ R + RR +Q L + AIIIQ+T R + RKKFL +AIVIQ R ++ ++ ++K
Sbjct: 676 ACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTI-----------------------RQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKRQLKQLK 827 HSP 5 Score: 63.1586 bits (152), Expect = 4.185e-9 Identity = 50/156 (32.05%), Postives = 83/156 (53.21%), Query Frame = 1
Query: 5410 ASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQ--LMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKR 5871
A I IQK R ++ R+ + K RK+ + +Q Y R Y+ F I + + +H +Y ++ K + QK R VR +L I++++I IQ+F R + + YQ L+ +IQ+ R ++ RK+FL ++ I+IQ +RR LAKR
Sbjct: 676 ACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLA-PYFAWI--YCIYLTEHA-------EYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKR 821 HSP 6 Score: 62.7734 bits (151), Expect = 5.617e-9 Identity = 55/179 (30.73%), Postives = 82/179 (45.81%), Query Frame = 1
Query: 3484 ITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSY--RHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQ-KYLRGFIKRKI 4011
I IQK +R LQRRRY+K +K+ I +QR R + YF C + E ++ + LIC+KQ+ RM+ ++ Y A +TI F +G F R+ Y + H I+IQ + R ++ RK FL + +AIVIQ Y R KR++
Sbjct: 678 IKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRG---------------YLAPYFAWIYCI----YLTEHAEYLRLTKAALICQKQY--------------RMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKRQL 823 HSP 7 Score: 62.003 bits (149), Expect = 1.110e-8 Identity = 61/214 (28.50%), Postives = 101/214 (47.20%), Query Frame = 1
Query: 2041 WRKYRTFYLYKTHFIAHYKEVI--IVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLV-------------QKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK---KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRR 2628
+ +YR K + K+V +++S+++ KF+ K +I V YL + R K + + I IQK R +L R RY KI+ + ++LQ + R YL YL++ ++ LI Q R R Y IR++ IQ + +G R+ +F+ KAI+ IQ RG+ R+ + AA++IQ YR + +R
Sbjct: 613 YSRYRVLMTKKDMTVGDKKQVCRNLLESLIKD---PDKFQFGKTKIFFRAGQVA-YLEKLRADKFRFACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAII-IQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKR 821 HSP 8 Score: 60.8474 bits (146), Expect = 2.596e-8 Identity = 45/148 (30.41%), Postives = 80/148 (54.05%), Query Frame = 1
Query: 4651 AAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIA-------------RKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRD--TRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRI 5049
A IK+QK +RG+L R+ + + R I++Q +G++A Y +L +++I QK +R + +L ++ A I IQ R +LY++ + +I+IQ+ VRG+L R K+ R AAI++Q +R+ L R++
Sbjct: 676 ACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKRQL 823 HSP 9 Score: 60.4622 bits (145), Expect = 3.150e-8 Identity = 45/141 (31.91%), Postives = 72/141 (51.06%), Query Frame = 1
Query: 5767 IQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAK-------------RSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYK--ILQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVR 6144
IQK R ++ R+R+L+I+ + I++Q++ R +LA Y R + Q R + Y +R A I IQ +G F R+ Y+ +L I +QR +RG+L RK FL+ +NA+I+I R VL +
Sbjct: 680 IQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAK 820 HSP 10 Score: 59.6918 bits (143), Expect = 5.487e-8 Identity = 52/168 (30.95%), Postives = 80/168 (47.62%), Query Frame = 1
Query: 4858 ASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLC-------------RIKYQRQLLAAIILQRHFR------KYLIIRRIDLEQKAARIIQNFYRGYTIR---AHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKV 5295
A I IQK VR + Q + Y R ++I++Q+Y RG+L +Y R AA+I Q+ +R YL IR +A IQ F RG R FL + + IQ + +L RKK+L R I IQC RR +++ + +LK+ ++++
Sbjct: 676 ACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIR------QAVITIQAFTRGMFTRRLYQEFLLH-HKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKRQLKQLKIEARSVKRI 836 HSP 11 Score: 58.151 bits (139), Expect = 1.737e-7 Identity = 42/137 (30.66%), Postives = 71/137 (51.82%), Query Frame = 1
Query: 4525 IQKIARGYLVRKRIVVEQKAVRIIQNFYRAH-------------TIRSHFICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQK--LRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRR 4890
IQK RG+L R+R + +K+ ++Q + R + T + ++ AA+ QK R +R+ + R +I +Q+ +G R+ YQ+ L +II+Q+ RG+ KKFL+ +NA+I IQ RR
Sbjct: 680 IQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRR 816 HSP 12 Score: 56.6102 bits (135), Expect = 5.011e-7 Identity = 46/138 (33.33%), Postives = 71/138 (51.45%), Query Frame = 1
Query: 4726 ILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNA-------------HKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLL--AAIILQRHFRKYLIIRRIDLEQKAARIIQNFYR 5094
I +Q ++G++ R+ Y K+R S+I++Q+ RG+ A H ++L+L A++ QK R + Y R A I IQ + RG R YQ LL AII+QR R +L ++ + AA +IQ YR
Sbjct: 678 IKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYR 815 HSP 13 Score: 53.9138 bits (128), Expect = 3.107e-6 Identity = 47/185 (25.41%), Postives = 85/185 (45.95%), Query Frame = 1
Query: 3853 GYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKR---KIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQ--MKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQ 4392
Y + + +R + I IQ + R ++ R+ +L I+ SAI++Q+Y RG++ IYC L +H ++ AA++ QKQ+R +R+ Y R+ VI IQ+ R + Y++ + A IQ+ +G++ RKK++ R +A++IQ
Sbjct: 663 AYLEKLRADKFRFACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYC----------------------------IYLTEH--------AEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQ 811 HSP 14 Score: 53.9138 bits (128), Expect = 3.323e-6 Identity = 42/160 (26.25%), Postives = 73/160 (45.62%), Query Frame = 1
Query: 3760 ILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFA-------------RKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRK 4200
I +Q +R + ++RY K + + + ++ +GY A +YL + ++ Q +R R+ +L+I+ + I IQ + RG R++Y + FL+ H A +IQ R + RK F+ RNAAIVIQ +R+
Sbjct: 678 IKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLY--------------QEFLL-------HHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRR 816 HSP 15 Score: 52.7582 bits (125), Expect = 7.326e-6 Identity = 56/175 (32.00%), Postives = 81/175 (46.29%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI-------------RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY--CLLKSYTLLIQ-------QRWRFIVLKRSAVVIQ----RIWRGRQLR 6375
L KL+ K R A I IQKTV+G+ R+ Y ++KS I LQR+ RG+L +L+L A++I K R V VR + +Q A I IQA+ R +R Y LL ++IQ R +F+ + +A+VIQ R+ RQL+
Sbjct: 665 LEKLRADKFRFACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIRQ---------------AVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKRQLK 824
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Cavefish
Match: myo5aa (myosin VAa [Source:ZFIN;Acc:ZDB-GENE-041027-2]) HSP 1 Score: 68.1662 bits (165), Expect = 1.235e-10 Identity = 56/171 (32.75%), Postives = 88/171 (51.46%), Query Frame = 1
Query: 4774 QKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRY---CQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSV 5277
KLR++ I +QK R + A KKFL++K A+I IQ++VR Y C R TR A+I+IQKY R ++ R Y+R+ AA+ +Q R Y+ AR Y+ L +++ V IQ + +L R+ Y +++QC VRR ++ +LK+
Sbjct: 770 DKLRAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGYQARCLATFLRRTR-AAIIIQKYQRMYVARTMYRRKQAAALAMQCILRAYM-----------AR---QLYK--------LLREHKAVIIQKMVRGWLARQWYKRSLDALVYLQCCVRRMRAKRELKKLKIEA 917 HSP 2 Score: 62.3882 bits (150), Expect = 7.170e-9 Identity = 48/158 (30.38%), Postives = 82/158 (51.90%), Query Frame = 1
Query: 5164 AYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKS-ATLIIQKHIRGIFVRLKYKKIIKLVVFIQ 5634
AYL + + ++R I IQ +R +++R +FLR+K + I IQ+ RGY Q + L TF A+IIIQK R Y+ R +++K+ + +Q +R Y+ +K+++ +IIQK +RG R YK+ + +V++Q
Sbjct: 762 AYLEKLRADKLRAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGY--------QARC-------------LATFLRRTRAAIIIQKYQRMYVARTMYRRKQAAALAMQCILRAYMARQLYKLLREHKAVIIQKMVRGWLARQWYKRSLDALVYLQ 898 HSP 3 Score: 60.8474 bits (146), Expect = 2.447e-8 Identity = 44/149 (29.53%), Postives = 82/149 (55.03%), Query Frame = 1
Query: 3886 RHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKR--KIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNF-ICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQ 4323
R + I IQ + RC++ RK FL +K +AI IQ+++RG+ R + +T A +IQK R ++ R +A +Q R+Y R+ + + + + A++IQK R RQ Y + ++++Q +R+ A ++ K++K A ++
Sbjct: 773 RAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGYQARCLATFLRRTRAAIIIQKYQRMYVARTMYRRKQAAALAMQCILRAYMARQLYKLLREHKAVIIQKMVRGWLARQWYKRSLDALVYLQCCVRRMRAKRELKKLKIEARSVE 921 HSP 4 Score: 59.3066 bits (142), Expect = 7.550e-8 Identity = 44/137 (32.12%), Postives = 77/137 (56.20%), Query Frame = 1
Query: 2200 YLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQ--KNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK--KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQ 2598
YL + R K++ + I IQK R +L R ++ ++K A + +Q H R Y + +L+ R+ +IIQ R Y+ R+ Y+R + + +Q ++ Y+AR+ K ++ KA V+IQ RG+ R+ Y + A V +Q
Sbjct: 763 YLEKLRADKLRAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGYQARCLATFLRRTRAAIIIQKYQRMYVARTMYRRKQAAALAMQCILRAYMARQLYKLLREHKA-VIIQKMVRGWLARQWYKRSLDALVYLQ 898 HSP 5 Score: 58.151 bits (139), Expect = 1.736e-7 Identity = 41/125 (32.80%), Postives = 71/125 (56.80%), Query Frame = 1
Query: 2404 GYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKR--RNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRS--CIIIQKYIRGFINRR 2766
YL + ++R + IQK ++ +LARKKF+++ +A + IQ RGY R + + +AA+IIQ + R V R Y + + + +Q ++ + R+L K LR +IIQK +RG++ R+
Sbjct: 762 AYLEKLRADKLRAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGYQARCLATFLRRTRAAIIIQKYQRMYVARTMYRRKQAAALAMQCIL-RAYMARQLYKLLREHKAVIIQKMVRGWLARQ 885 HSP 6 Score: 57.3806 bits (137), Expect = 2.471e-7 Identity = 44/139 (31.65%), Postives = 79/139 (56.83%), Query Frame = 1
Query: 2140 LKKFKSIKMRI--IICQSVVKRYLARHRISKMKKSAILIQKNYRRYL--CRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTK-IIQKYVKGYLARKKFVKLTKAIVVIQSAFR 2541
L+K ++ K+R I Q ++ +LAR + +MK++AI IQ++ R Y C + + A +++Q + R Y+ + Y + + L +Q +R Y+ R YK +R+ IIQK V+G+LAR+ + + A+V +Q R
Sbjct: 764 LEKLRADKLRAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGYQARCLATFLRRTRAAIIIQKYQRMYVARTMYRRKQAAALAMQCILRAYMARQLYKLLREHKAVIIQKMVRGWLARQWYKRSLDALVYLQCCVR 902 HSP 7 Score: 56.6102 bits (135), Expect = 4.023e-7 Identity = 56/209 (26.79%), Postives = 102/209 (48.80%), Query Frame = 1
Query: 5440 CYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSN-IIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKIL----QKSVIQLQR 6051
Y+ + K R C++IQ IR ++ KF +K A + IQ+H+RG R L F+++ RA I+ IQ + RM+ Y+ + + +Q R ++AR+ + ++ + +IIQK R +LA++ Y+R+L ++++Q VR AK + +K++ ++ HYK L + ++QLQR
Sbjct: 762 AYLEKLRADKLRAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGYQARC-------LATFLRR-TRAAII-------------IQKYQRMYVARTMYRRKQAAALAMQCILRAYMARQLYKLLREHKAVIIQKMVRGWLARQWYKRSLDALVYLQCCVRRMRAKRELKKLKIEARSVE----------HYKKLNIGMENKIMQLQR 939 HSP 8 Score: 54.299 bits (129), Expect = 2.180e-6 Identity = 42/147 (28.57%), Postives = 73/147 (49.66%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIR--KIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRG 6363
L KL+ K+R A I IQKT++ + RK + ++++ I +QR +RG+ R FL+ A+III K+ R + R + R++ A++ +Q R Y+ ++ Y LL+ + AV+IQ++ RG
Sbjct: 764 LEKLRADKLRAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGYQARCLATFLRRTRAAIIIQKYQRMYVARTMY---------------RRKQAAALAMQCILRAYMARQLYKLLREH---------------KAVIIQKMVRG 880 HSP 9 Score: 52.373 bits (124), Expect = 9.412e-6 Identity = 40/126 (31.75%), Postives = 72/126 (57.14%), Query Frame = 1
Query: 3025 ALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRS--IICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKS-TIIIQKHFRAISARKQF 3393
A +++ + LR A I IQKT RC+ RKKFL +AI IQ++VR C +L+ ++ ++IQK+ + ++ + Y++ + Q ++R Y+ ++ Y +R+ +IIQK R AR+ +
Sbjct: 762 AYLEKLRADKLRAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGYQARCLATFLRRTRAAIIIQKYQRMYVARTMYRRKQAAALAMQCILRAYMARQLYKLLREHKAVIIQKMVRGWLARQWY 887
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Sea Lamprey
Match: myo10l1 (myosin X, like 1 [Source:ZFIN;Acc:ZDB-GENE-080425-1]) HSP 1 Score: 53.9138 bits (128), Expect = 6.335e-7 Identity = 24/68 (35.29%), Postives = 41/68 (60.29%), Query Frame = 1
Query: 3328 KVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRY 3531
++ KS +I+ H A ARK+F R + VQ + + C+++F +L++ IT+QK+ R+ L RR Y
Sbjct: 737 ELHKSATLIRAHVLAYLARKRFRRLRACAVAVQAWFRCRSCQRRFSRLRASAITLQKHRRSALARRLY 804
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000990.1 (pep scaffold:Pmarinus_7.0:GL476918:15609:106669:1 gene:ENSPMAG00000000865.1 transcript:ENSPMAT00000000990.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 51.6026 bits (122), Expect = 2.467e-6 Identity = 52/215 (24.19%), Postives = 99/215 (46.05%), Query Frame = 1
Query: 2203 LARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCR------SNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIII---------QKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNIL 2802
L R R +M + A LIQK YR Y CR + +K + +++ S+ R + +K Y+K I+++Q +RG+ R + K++ + +I+ Y G+ ++ K AI V + +++++ + +Q+ R V +R L RK + + + H+ FK KR+ +I+ I RR FL+ + ++ L
Sbjct: 696 LERKRTERMHELATLIQKTYRGYKCRTHFLLMKKSQIIIASYVRSHQERKRYVKTLECIVLLQRIVRGWKARRLLRHLKHQKKLNDAATVIRAYWCGFQTKRGKRKAFLAIPVSR-----------HSLKLTPILWLQAKVRRQVNQRKELGRRKHAVAVIWAYWTGLKVRKAHRKHFKGNAGKRIYDFLIL------CIMRRYFLRLQDSLPKL 893
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004311.1 (pep scaffold:Pmarinus_7.0:GL481322:4319:21833:1 gene:ENSPMAG00000003937.1 transcript:ENSPMAT00000004311.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 48.1358 bits (113), Expect = 8.093e-6 Identity = 32/106 (30.19%), Postives = 55/106 (51.89%), Query Frame = 1
Query: 5191 EIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIR 5508
E+ + IQ R+Y R + M+ +IQ+ R Y + Y K +A I IQ FR + E K FQ + A+++IQ+ +R Y ++ K+ R+ + +Q +R
Sbjct: 118 ELYEAAKIIQTAFRKYKGRRLKEQQDMAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQYYRSYKEYEKLKQTRRGTINLQQKMR 223
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Yeast
Match: MYO2 (Type V myosin motor involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle; MYO2 has a paralog, MYO4, that arose from the whole genome duplication [Source:SGD;Acc:S000005853]) HSP 1 Score: 63.1586 bits (152), Expect = 5.689e-10 Identity = 47/144 (32.64%), Postives = 71/144 (49.31%), Query Frame = 1
Query: 3961 SAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQ--SATLIQHFYRSYKIRKNFIC-------------------------KRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAA 4311
S ++IQK +R RK Y + AIK +Q NI+GF++R+ +N + ATL+Q YR + IR N + NAA+ IQ + R R ++ T+K + +QSLIR+ A +K KQ+K A
Sbjct: 787 SIVMIQKKIRAKYYRKQYLQISQAIKYLQNNIKGFIIRQRVNDEMKVNCATLLQAAYRGHSIRANVFSVLRTITNLQKKIRKELKQRQLKQEHEYNAAVTIQSKVRTFEPRSRFLRTKKDTVVVQSLIRRRAAQRKLKQLKADA 930 HSP 2 Score: 53.9138 bits (128), Expect = 3.464e-7 Identity = 54/182 (29.67%), Postives = 91/182 (50.00%), Query Frame = 1
Query: 5131 NSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSV---IIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLK-----NASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRAN 5652
NS V IQ +A RK+YL+I Q ++Q ++ +I R R + +M V ++Q RG+ + + N+QK R+ ELK Q LK NA++ IQ R + R F + +K+ V +QS IRR K K +K+ + H++ + +L+ K+I+L + ++ N
Sbjct: 786 NSIVMIQKKIRAKYYRKQYLQISQAIKYLQNNIKGFIIRQR-VNDEMKVNCATLLQAAYRGHSIRANVFSVLRTITNLQKKIRK--ELKQRQ-LKQEHEYNAAVTIQSKVRTFEPRSRFLRTKKDTVVVQSLIRRRAAQRKLKQLKADAKSV-NHLKEVSYKLE-NKVIELTQNLASKVKEN 961 HSP 3 Score: 53.9138 bits (128), Expect = 4.169e-7 Identity = 57/207 (27.54%), Postives = 101/207 (48.79%), Query Frame = 1
Query: 2134 LCLKKFKSIKMRIIICQSVVKRYLARHRISKMK----KSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKI-----IQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNY--TIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRS 2721
L KK ++ + II SVVK L K K + I + YL ++R K+ ++ V++Q R +K YL+I ++I +QNNI+G++ R +R+ K+ +Q +G+ R + + I +Q R K+R + AAV IQS R+ R +L +K +++Q ++ + +RKL K+L++
Sbjct: 729 LIFKKKETTEEDII---SVVKMILDATVKDKSKYQIGNTKIFFKAGMLAYLEKLRSNKMHNSIVMIQKKIRAKYYRKQYLQISQAIKYLQNNIKGFIIR---QRVNDEMKVNCATLLQAAYRGHSIRANVFSVLRTITNLQKKIRKELKQRQLKQEHEYNAAVTIQSKVRTFEPRSRFLRTKKDTVVVQSLIRRRAAQRKL-KQLKA 928
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Yeast
Match: MYO4 (Type V myosin motor involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p; MYO4 has a paralog, MYO2, that arose from the whole genome duplication [Source:SGD;Acc:S000000027]) HSP 1 Score: 51.9878 bits (123), Expect = 1.433e-6 Identity = 55/193 (28.50%), Postives = 95/193 (49.22%), Query Frame = 1
Query: 5899 IFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIR-KIFLKLKN-ASIIISKHVRGVLVRNHFQKN-KQHMK---------IFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKIG--HEISEIRNRFI 6435
IF ++ + L KL+ KM I+IQK ++ + R Y +S+ + Q IR L+R ++ +LK A+I++ ++R + R +++ Q +K I N + L A++ IQ+Y R Y K Y LK ++L+Q R + +R +V+Q+ R +R + IG E E +N FI
Sbjct: 762 IFFKAGMLAFLEKLRTNKMNEICIIIQKKIRARYYRLQYLQTMESIKKCQSQIRSLLVRTRVDHELKTRAAILLQTNIRALWKREYYRAAIGQIIKLQCTCKRKLILDSVNRKFMLMAAVIIQSYIRSYGHKTDYRTLKRSSILVQSAMRMQLARRRYIVLQKEVEERNIRA---SYGIGLLEEAIEFKNSFI 951
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Nematostella
Match: EDO41819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3A8]) HSP 1 Score: 68.9366 bits (167), Expect = 2.796e-11 Identity = 49/178 (27.53%), Postives = 100/178 (56.18%), Query Frame = 1
Query: 2188 VVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIR--KSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQI--KAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEK 2709
+++ ++ + +M K+ I + YL ++R +K++ + V++Q ++R Y K YL++ ++ ++IQ +RG R+ + +R KS IQ+Y +G+ R+ +++ AI+ IQS RG + RR + + A +IQ +R R+ Y N K +I +Q V ++ +++L+K
Sbjct: 705 ILETFIKDEDMFQMGKTKIFFRAGQVAYLEKLRGDKLRRSCVMIQKNYRCYREHKLYLRMRKAAILIQAWVRGDQARNLARSLRRNKSATTIQRYYRGFHLRQAYLRKHAAILTIQSYARGMSARRQRQVLLYNAKAGVIQRCWRGYKGRQKYRNYFKKIIFLQSCVRRMRARKELKK 882 HSP 2 Score: 63.1586 bits (152), Expect = 1.376e-9 Identity = 46/150 (30.67%), Postives = 83/150 (55.33%), Query Frame = 1
Query: 3886 RHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCS--QTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIR--KNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQ 4323
R S ++IQ ++RC+ K++L ++ +AI+IQ ++RG R + S + + IQ+ RGF +R+ H + IQ + R R + + A VIQ+ +R + RQ+Y KK+IF+QS +R+ A ++ K++K A ++
Sbjct: 742 RRSCVMIQKNYRCYREHKLYLRMRKAAILIQAWVRGDQARNLARSLRRNKSATTIQRYYRGFHLRQAYLRKHAAILTIQSYARGMSARRQRQVLLYNAKAGVIQRCWRGYKGRQKYRNYFKKIIFLQSCVRRMRARKELKKLKIEARSVE 891 HSP 3 Score: 62.003 bits (149), Expect = 3.118e-9 Identity = 43/151 (28.48%), Postives = 84/151 (55.63%), Query Frame = 1
Query: 3304 YLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQ--KFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFR--SCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQK 3744
YL + + K+R+S ++IQK++R K +L RK I++Q +++ Q R + L+ TIQ+ R R+ Y++ A++ IQ R S + ++Q++L N A V+Q+ ++ Y ++++R + + +Q RR+ RK+ +K
Sbjct: 732 YLEKLRGDKLRRSCVMIQKNYRCYREHKLYLRMRKAAILIQAWVRGDQARNLARSLRRNKSATTIQRYYRGFHLRQAYLRKHAAILTIQSYARGMSARRQRQVLLYNAKAGVIQRCWRGYKGRQKYRNYFKKIIFLQSCVRRMRARKELKK 882 HSP 4 Score: 56.225 bits (134), Expect = 2.166e-7 Identity = 51/149 (34.23%), Postives = 80/149 (53.69%), Query Frame = 1
Query: 4846 KLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCR--IKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARI-IQNFYRGYTIR--AHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSV 5277
KL+ + + IQKN R Y + KLY R A+I+IQ +VRG R + R+ +A +QR++R + +R+ L + AA + IQ++ RG + R L IQ ++ Y R+KY +K IF+Q VRR +R +LK+
Sbjct: 740 KLRRSCVMIQKNYRCYREHKLYLRMRKAAILIQAWVRGDQARNLARSLRRNKSATTIQRYYRGFH-LRQAYLRKHAAILTIQSYARGMSARRQRQVLLYNAKAGVIQRCWRGYKGRQKYRNYFKKIIFLQSCVRRMRARKELKKLKIEA 887
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Nematostella
Match: EDO35658 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKY6]) HSP 1 Score: 55.0694 bits (131), Expect = 5.354e-7 Identity = 34/116 (29.31%), Postives = 61/116 (52.59%), Query Frame = 1
Query: 5533 KMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQ 5880
+++ S ++IQK +RG R Y ++ V IQK + + R ++ I + +Q+ YR YQ ++ + + Q CR F+AR+ ++ +++I IQ R LAKR+ Q
Sbjct: 490 RLLTSRAILIQKVVRGFLTRKVYLRMRMGAVMIQKTWKGHHQRQKYQKILQGYARLQALYRTRVISAKYQTLRSRVCIFQAYCRGFLARRDYVTRINSVIKIQSGVRMVLAKRTAQ 605 HSP 2 Score: 53.9138 bits (128), Expect = 1.014e-6 Identity = 33/106 (31.13%), Postives = 56/106 (52.83%), Query Frame = 1
Query: 2452 IIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRN 2769
+IQK V+G+L RK ++++ V+IQ ++G+ +R+ Y ++ +Q+ YR+ V Y LR V I Q L +R R+ S I IQ +R + +R
Sbjct: 498 LIQKVVRGFLTRKVYLRMRMGAVMIQKTWKGHHQRQKYQKILQGYARLQALYRTRVISAKYQTLRSRVCIFQAYCRGFLARRDYVTRINSVIKIQSGVRMVLAKRT 603 HSP 3 Score: 53.5286 bits (127), Expect = 1.531e-6 Identity = 33/104 (31.73%), Postives = 56/104 (53.85%), Query Frame = 1
Query: 4102 ATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYL 4413
A LIQ R + RK ++ R A++IQK ++ H+ RQ+Y + + +Q+L R + KY+ ++ Q +G++ R+ YVT+ S + IQ VR L
Sbjct: 496 AILIQKVVRGFLTRKVYLRMRMGAVMIQKTWKGHHQRQKYQKILQGYARLQALYRTRVISAKYQTLRSRVCIFQAYCRGFLARRDYVTRINSVIKIQSGVRMVL 599 HSP 4 Score: 51.2174 bits (121), Expect = 6.498e-6 Identity = 38/144 (26.39%), Postives = 72/144 (50.00%), Query Frame = 1
Query: 2110 VQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFR 2541
+I ++L ++ K +I + + + L HR + AILIQK R +L R Y +++ V++Q ++ + ++ Y KI + +Q R + + Y+ +R I Q Y +G+LAR+ +V +++ IQS R
Sbjct: 454 TNNIAVKYLSNSDWQLGKTKIFL-KDAQDQQLEEHRDRLLTSRAILIQKVVRGFLTRKVYLRMRMGAVMIQKTWKGHHQRQKYQKILQGYARLQALYRTRVISAKYQTLRSRVCIFQAYCRGFLARRDYVTRINSVIKIQSGVR 596 HSP 5 Score: 51.2174 bits (121), Expect = 6.552e-6 Identity = 33/113 (29.20%), Postives = 60/113 (53.10%), Query Frame = 1
Query: 5620 VVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMR 5958
+ IQK +R + R +L ++ + IQ ++ H++ + YQ + Q +Q R + ++ ++S + I Q + R FLA+R Y ++ +I +QS VR LAK Q +R
Sbjct: 496 AILIQKVVRGFLTRKVYLRMRMGAVMIQKTWKGHHQRQKYQKILQGYARLQALYRTRVISAKYQTLRSRVCIFQAYCRGFLARRDYVTRINSVIKIQSGVRMVLAKRTAQGLR 608
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Nematostella
Match: EDO49515 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGF6]) HSP 1 Score: 52.373 bits (124), Expect = 2.671e-6 Identity = 29/82 (35.37%), Postives = 47/82 (57.32%), Query Frame = 1
Query: 4774 QKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCR-----IKYQRQLLAAI 5004
+ ++I+QKIFRG+ K++ ++ + I I K RR+ + YR RNA+I+I Y RG+ R I Y+RQ + A+
Sbjct: 707 DGMEDLAVIIQKIFRGWRRKKQYQNMRRSEITIAKYYRRFRDQRDYRRMRNAAILIASYARGWKARKAYRAILYERQCIWAV 788
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Medaka
Match: aspm (abnormal spindle microtubule assembly [Source:NCBI gene;Acc:101174988]) HSP 1 Score: 596.275 bits (1536), Expect = 1.426e-172 Identity = 563/2158 (26.09%), Postives = 1015/2158 (47.03%), Query Frame = 1
Query: 589 DDIWLKRQEDCFVKWLNCIFNTHLSKTKVEDINK-------------NMP---------------------IYIEATKLLLSECKV-AIEKINSEVTKDSLKF-KDDIFFKSGKHHRDLTELIMNYNDPWLFLAFNVSIDPDFNVSLLSNNEA-CFKKFIACKILWNKDIAKKHRMKDINSYRKPEFNLSLNRNILRQFLSIVYILDVAKKNNIFPSDINLFRKDSNVKSSAEMLTEFTSYFLKGEGNILKRFSNWNLSVSHIQTAIDEYDFTVSNLSDDITDGVRLARLAKIL-VNIDIMSKLRYPAVDLARKTFNIELAVKAFKDAGTAIVTYSGEEIDLSQIPWGHREKTLALLWCVLSRHYIDAVIDRDKLISEIKLF--------------------ENPIXXXXXXXXXXXXV-----WVKSVCGLYNINVSNISNL-KDGRGFCLLIHYYLPEYLKLNEINHNTTLT-------------------------------SANLFDKEILLENEKRNFQIFFSKLKQIGGAPIIL---PKENEIPSHEFIMATLAFFSSRLIDLMTFYRAASCIQRVWRKYR---TFYLYKTHFIAHYKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRISKMKKSAIL----------IQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLC----RSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLR----SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLR----RKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRA--LIQRRKFQY--LRNAAIIIQKTFRCYSVRKKF--------LIQYY---------------SAIVIQKNVRSIICQKN----YLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCK----EKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKR----YQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIK----VIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYI----RQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIR----KNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQK----NVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYR----GYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQ----KKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICIS----KFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRM----HYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKL----KYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLKNASIIISKHVRGVLVRNHFQKNKQH------------MKIFAQENLRKRL----EASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-----------FIVLKRSAVVIQRIWRGRQLR 6375
D+ W+++QE F W+N + K E +NK N+P + A +L SE AI+++ EV L KD ++ + + +++YN WL + +I +F + L SN++ FI ++LWN DIA ++R + + K +L+R L++ L +V LD AK+ + + LF D+ K++ ++L F+ FL GEG + + L VSH+QT +DE+DF V NL+ D+ G+RLAR+ ++L ++ + +KLR PA+ +K N++LA++ K G + G ID I GHREKTL+LLW ++ +++ ++D ++L EI +P+ + + WV++VC YN+ V N + + DGR C LIH+Y P L I+H+TT T S ++ KE LLENEK NF++ S + +GG P ++ N IP + +M L+F +RL+DL RAA IQ WRKYR LY+ K + +Q +VRRFL ++ ++ QS + +LAR +I +M+K A+L IQ ++R + Y +++ TV +Q+ +R Y K+ R++ ++Q R + R Y +R S +Q+ + + A K + +A VVIQ+AF+ + R T + AAV IQS++R VC R Y +R+S ++IQ H+ +R+ + L+ S ++IQ+ RG + R+ L+ + A +++ F ++ R+ FL MR + + +Q R R + ++A +IQ +F+ A+K+++A + A I +Q + RA L ++ K QY LR AA+++Q ++R + RKK LIQ +A+VIQ+ R+ + K+ +L+ + + + +Q +G V+ K+ + QS +R++L +K+Y ++ + IIIQ +RA+ +++K+F ++ I +Q + + RQ+ K + IQ + R R Y+ K A I IQ ++R+ K E+++ AA V+Q ++ + +++ + + +IQ+ + RKQF K + ++ Q + R + ++ Y K A + + +GY RK+ + + ++IQ+ FR + + ++++ V+Q+ R K ++ A+K V+Q RG R+ L HQ+A +IQ +R++ ++++ + + + IQ+++R + + QY + RK I +Q++ R ++ + +AAT IQ + Y K+ R SA IIQ+ R L ++ + R FL +A ++Q RG+ VR + A +IQ +R + F ++ AA+ LQ+ R + K + + R +L+Q+ +G +R+ Q+ ++ ++Q+ FR H+ +L LK + + IQ+ N+ Q Y+ R A+I++Q RG R + R AA ++Q FR+Y + + +A IIQ YR G T R +FL K S V +Q F+ + +R + + IQ RR+ + F R + + +++Q+ R R VKQ +KA + +Q +R + Q A+ +IQ++FR + + + + + + IQ R + +++ I+ AT+++Q RG VR + + IQ R +F ++ S IQ YR + +N+ MK+S V+Q R + R + S ++IQ FRRF +++++R + +Q R + K +Y K+R A +L+Q +G R+ + ++ +QR R + ++ LK + + I + R N K ++H ++ + +RK + A+ IQ+ FR Y ++ ++ ++ +IQ+R+R F+ +KRSAVV+Q +RG ++R
Sbjct: 701 DERWIEKQERGFTWWINYVLTPDDFKVNPE-VNKASAVSLAIGSDKFNVPRAPTKEEMSFSTYTARRKLNRLRRSACQLFTSEAMAKAIQRLELEVEARRLLVRKDRHLWRDIGERKKVLNWLLSYNPLWLRIGLE-TIFGEF-ICLESNSDTLGLAMFILQRLLWNPDIAAEYRHHRVPNLYKEGHEEALSRFTLKKLLLLVCFLDKAKECRLIEHNPCLFCVDAEFKATKDLLLAFSRDFLSGEGILPRHLGYLGLPVSHVQTPLDEFDFAVKNLAVDLKCGIRLARVMELLTLDWRLSAKLRLPAISRLQKIHNVDLALQVLKAKGIDLKDEHGSIIDSRDIVDGHREKTLSLLWKIIFAFHVEVILDENQLRQEIGFLRRTLRTKRRLARVRADQGIQPSPMKTRVSYEHTSTKITLLMEWVRAVCNFYNLKVENFTVMFSDGRVLCYLIHHYHPSLLPEASISHSTTQTVEGSPTGRLELDCSASDSDSSFDALKKGGPDSPSVVFKE-LLENEKSNFKLVNSAVAFLGGVPAMINLADMSNTIPDEKVVMTYLSFLCARLLDLHNETRAARVIQGAWRKYRLKKDLQLYEE----RNKAALKIQLMVRRFLQKRRAARRAQAAVLIQSAWRGFLAR-KILRMQKEALLRAVQHEAATIIQAHWRMFSAFKAYNQLRYYTVSVQAQWRMRRAAATYGKVCRAVRVLQKYSRAWALSRKQRDRYLLLRSSVVKLQRAFRRWKA-TKIEEENRAAVVIQAAFKKWYSHRMAT-KSAAAVRIQSWFRMQVCHRDYSQIRRSAVLIQ-AYHRGQVQRRRFQTLKLQHDSAVVIQRAFRGHVVRKQVLEMRQAAVVIQQRFRASVKRNAQRRAFLTMRCAAVAMQAVFRGKKARELLKKQHEAATVIQAAFRERAARKKYLALRKAAIRVQRRYRATVLARKTKTQYFALRKAALVLQASWRGRADRKKIEMWHRCATLIQASYRRHRIHAEFRSKKGAALVIQRRYRAFVAGKDIRGKFLQKRAASIALQAGFRGMRVRSELKRKHQAATVIQSWIRRFLCEKRYFLMQCAAIIIQSRYRALLLCRASQKEFRKQKQAAIKIQAVFRGLRVRQEHRKRIAAATAIQAHFRMYKMRMAYLAAKFAAIIIQERYRAKKLRDQERQRYKRIKSAAVVIQAAYRGCMVRRRMAERHRAAAIIQRMFLTIQARKQFLKLKSVALICQRRYRALSLARKFHLDYLSKRRAVVCLQAACRGYLVRKQLHVRQRAAVIIQSYFRMHQRKTRYRRLRWACRVVQERCRANKKMRVDMHAMKAVKNAAIVLQSAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMAAKKQKSQYQQIRKATILLQAVYRGQQVRKEVGRWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRTDR-------------RNFLNMKC------SAVVLQAAFRGHRVRTDVANMHSAAVVIQANFRRFREQKTFRRRRWAAVVLQQRFRAQKQKQHAVKQYYKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMAAKKQKSQYQQIRKATILLQAVYRGQQVRKEVGRWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRTDRRNFLNMKCSAVVLQAAFRGHRVRTDVANMHSAALVIQANFRRFREQKTFRRRRWAAVVLQQRFRAQKQKRHAVKQYHKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMAAETQKHQYQQIRKATILLQAVYRGQQVRKEVGHWHQAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRRDRRNFLRMKRSAVVLQAAFRGYRVRTDVANMHSAAVVIQSNFRRFREQKTFRRRRWAAVVLQQRFRAQKQKRHAVKQYHKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYVTLKASVLNIQRRYRA----NMAAKTQKHQYQQIRKATILLQAVYRGQQVRKDVGHWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRTDRRNFLRMKRSAVVLQAAFRGHRVR 2823 HSP 2 Score: 401.749 bits (1031), Expect = 7.422e-112 Identity = 454/1791 (25.35%), Postives = 813/1791 (45.39%), Query Frame = 1
Query: 2092 YKEVIIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYL----ARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRK-----LEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQK----NYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAI----SARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIR---------------ALLQRR------------RYIKNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQK-YQRRLICRKQ---FQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMY----RKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKT------------------------LNSHHQ---SATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQ----KYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLL----AATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIRGYLIR----KNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQK----NVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYR----GYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQ----KKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICI----SKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIR--------------ANIVRTR-------------FLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFR----RFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLI----RKIFLKLKNASIIISKHVRGVLVRNHFQKNKQH----------------MKI-------FAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQ---RW----------------RFIVLKRSA------VVIQRIWRGRQLRCHL-NAK--KIGHEISEIRNRFIEANRRFSKFNTVRYIGKKALTDLKESELTVAKVLFCLTSLENVTSLSREICKWLIESDAYKILLELLHDCNRGVADLEVVSKVISVFFNLGKAGVLNFDVIGSE-FIKLVKNLLYR---NINSKRGTKGITIFCHTCLLLVLLIKMEQKS 6873
++ ++QS +RRFLC K++ ++ II QS + L ++ K K++AI IQ +R R + K +A +Q+HFR Y ++ YL + +IIQ R K++R R+++ ++ A VVIQ+A+RG RR + +AA IIQ + + R+ +L L+ +I Q+ + RK L KR R+ + +Q RG++ R+ + A I++ YF + R+ ++ ++R + ++Q+ R N + A+ A K+A I++Q+ R + RR Q AA +IQ++FR + + +L S + IQ+ R+ + K Y +I+++ +++Q +G V+K + + QS R+Y + ++ +R S IIQ+ +RA+ + R+ FLN + +V+Q + H+ R + S + IQ N R +LQ+R +Y K +KA + +Q +R K ++ + +QAA V+Q+ F+++ + + +K SV IQ+ Y+ + +KQ +Q+ K ILLQ+ R +K + A I + Y K+ + R S +IQ +R + R+ FL++K SA+V+Q RG R + +A VIQ N R F +KT + +H+ +A L+Q YR K R+ + AA VIQ+ FR H + Y + V+ IQ R +A + +Y+Q++KA +Q + +G +RK+ ++A +IQ R+Y FQ + S IIQ+ R L +R L +A ++Q RGY VR + A +IQ+ +R + F ++ AA+ LQ+ R + K + + R +L+Q+ +G +R+ Q+ ++ ++Q+ FR H+ ++ LK + + IQ+ N+ Q Y+ R A+I++Q RG R AA ++Q FR+Y + + +A IIQ YR G T R +FL K S V +Q F+ + +R + + IQ RR+ + F R + + +++Q+ R + VKQ +KAV+ +Q +R + Q A+ +IQ++FR + + + + + +KIQ R + +++ I+ AT+++Q RG VR + + + IQ R A I++ R FLN+K S + +Q+ +R H + M + VIQ N R+F +K F + +++Q+ FR + A + Y + + +Q+ RG ++ Q+ A +IQ++ + + + Y L+ SV+ +QR R ++ RKI+++ + A+++I + R R + + MKI +A E+ +K++ + + IQ + R Q+R Y + + Q+ RW +F+ +KR V Q +WR R H NAK K+ H + +I E ++ +K ++ AL L + + +L L +LE T LS E C+ L++S A ++ L+ CNR V ++V++ I + NL K V E ++ + +LL R K KG +IF C LL LL++ ++++
Sbjct: 1735 HQAATVIQSWIRRFLCEKRYFLMQCAAIIIQSRYRALLLCRASQKEFRKQKQAAIKIQAVFRGLRVRQEHRKRIAAATAIQAHFRMYKMRMAYLAAKFAAIIIQERYRA-------KKLRDQE------------RQRYKRIKSAAVVIQAAYRGCMVRRRMAERHRAAAIIQRMFLTIQARKQFLKLKSVALICQRRYRALSLARKFHLDYLSKR-RAVVCLQAACRGYLVRKQLHVRQRAAVIIQSYFRMHQRKTRYRRLRWACRVVQERCRA----NKKMRVDMHAMK---------------AVKNAAIVLQSAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMAAKKQKSQYQQIRKATILLQAVYRGQQVRKEVGRWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRTDRRNFLNMKCSAVVLQAAFRGHRVRTDVANMHSAAVVIQANFRRFREQKTFRRRRWAAVVLQQRFRAQKQKQHAVKQYYKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMAAKKQKSQYQQIRKATILLQAVYRGQQVRKEVGRWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRTDRRNFLNMKCSAVVLQAAFRGHRVRTDVANMHSAALVIQANFRRFREQKTFRRRRWAAVVLQQRFRAQKQKRHAVKQYHKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMAAETQKHQYQQIRKATILLQAVYRGQQVRKEVGHWHQAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRRDRRNFLRMKRSAVVLQAAFRGYRVRTDVANMHSAAVVIQSNFRRFREQKTFRRRRWAAVVLQQRFRAQKQKRHAVKQYHKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYVTLKASVLNIQRRYRANMAAKTQKHQYQQIRKATILLQAVYRGQQVRKDVGHWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRTDRRNFLRMKRSAVVLQAAFRGHRVRTDVANMHSAALVIQANFRRFREQKTFRRRRWAAVVLQQRFRAQKQKQNAVKQYHKIRKAVVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKSSVLKIQRRYRANMAAKTQKHQYQQIRKATILLQAVYRGQQVRKEVGRWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRRDRRNFLNMKCSAVVLQAAFRGHRVRTDVANMHSAAVVIQANFRRFREQKTFRRRRWAAVVLQQRFRAQKQKQNAVKQYHKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMVAKGERKIYIQKRQATMLIQRSFRAWKARQQVVQAARAEKRLRFTAVVFHHLCAMKIQRALRAHWALESAKKQINSVVTIQRWLRARQQRRHYLEERGKVVTAQRAVRRWLAHRHKAASVIQLTVRKFLDVKRQQRVQRGIVKAQALWRAHCSRQHHDNAKLVKLRHRLRQISAEVREEDKLCNKTSS-------ALDYLLRYK-HFSYILEALQNLETATRLSPECCERLVQSGATNVIFTLIRCCNRSVPCMDVITFSIQILLNLSKYQKTIEAVYSVENSVETLLDLLQRYREKAGDKVAEKGGSIFTKACFLLALLLQDKRRA 3478 HSP 3 Score: 377.096 bits (967), Expect = 2.400e-104 Identity = 389/1537 (25.31%), Postives = 725/1537 (47.17%), Query Frame = 1
Query: 2221 SKMKKSAILIQKNYRRYLCRIRYEKIK---SATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKR----IRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSV-CRRT---YLNLRKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLR----RKQFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALI----QRRKFQYLRNAAI-----------------------IIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQ----KNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAIS-ARKQFLNF--------------------------RKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAV----IFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQK-YQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQK----YLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFR----KHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKAATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHFICQKNAAIKLQKNIR----GYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRRYCQ----MKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFR------KYLIIR----------RIDLE-----------QKAARIIQNFYRGYTIRAHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQ----CLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCYILR----KEFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIV----RTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNL----SIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIR----KIFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWR-----------FIVLKRSAVVIQRIWRGRQLR 6375
S++++SA+LIQ +R + R R++ +K + VV+Q FR ++V+K L++ ++ ++IQ R + R+ +R +R + +Q +G AR+ K +A VIQ+AFR A R+ Y KAA+ +Q YR++V R+T Y LRK+ +++Q ++K+E R +IQ R F K A +++ + ++ R +FL+ R + I LQ R + +R+ K ++A +IQ +R+ +K + + A I+IQ++ RAL+ +++F+ + AAI IQ FR Y +R +L ++AI+IQ+ R+ + + Y +IK + +VIQ +G +V++ + I Q + +KQ+LK++ +I Q+ +RA+S ARK L++ ++ +++Q Y +MHQ + ++ +L+ +Q+ RA + R + KAV I +Q +R K ++ + +QAA V+Q+ F+++ + + +K SV IQ+ Y+ + +KQ K +YQ+ AT+ + +G RK+ + + VIQ++FR + F +++ SA +IQ+ L+G R+ + + + V+Q RG VR + + H +A +IQ +R ++ +K F +R AA+V+Q++FR K + +QY + RK + +Q+ R + + +Q +AA IQ+ + + + Y+T + S + IQ+ R ++ K +S Y++ A L+Q + RG VRK + +A +IQ+ +R + F + +A +Q+ R G R+NF + +++Q+ +G R + S+++++Q FR F K F + + A++ +Q+ R Q +K Y R A++++Q RG R Q++ AA ++QR FR YL ++ R ++ +KA ++Q YRG +R + IQ+ F+ Y K+ +R IQ L++ R FLR+K S +++Q RGY A + IQ NFRRF E KTF+ + A++++Q+ FR + K++ K RK V +Q+ R + A +IQ+ R Y + V+ IQ+ RAN+ + ++ I+K+ I +Q+ YR K+ ++ TVIQ R++ +F ++ + IIQ+ +R L R+ +RN + +Q+ RG + M +A ++IQ + + +K ++ + + + LQ+ R + K + K++ A +++ RG+ R +I QE+ +A+ IQ FR + + R Y LKS L IQ+R+R + ++++ +++Q ++RG+Q+R
Sbjct: 1487 SQIRRSAVLIQAYHRGQVQRRRFQTLKLQHDSAVVIQRAFRGHVVRKQVLEMRQAAVVIQQRFRASVKRNAQRRAFLTMRCAAVAMQAVFRGKKARELLKKQHEAATVIQAAFRERAARKKYLALRKAAIRVQRRYRATVLARKTKTQYFALRKAALVLQASWRGRADRKKIEMWHRCATLIQASYRRHRIHAEFRSKKGAALVIQRRYRAFVAGKDIRGKFLQKRAASIALQAGFRGMRVRSELKRKHQAATVIQSWIRRFLCEKRYFLMQCAAIIIQSRYRALLLCRASQKEFRKQKQAAIKIQAVFRGLRVRQEHRKRIAAATAIQAHFRMYKMRMAYLAAKFAAIIIQERYRAKKLRDQERQRYKRIKSAAVVIQAAYRGCMVRRRMAERHRAAAIIQRMFLTIQARKQFLKLKSVALICQRRYRALSLARKFHLDYLSKRRAVVCLQAACRGYLVRKQLHVRQRAAVIIQSYFRMHQRKTRYRRLRWACRVVQERCRANKKMRVDMHAMKAVKNAAIVLQSAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMAAKKQ--------------------KSQYQQIRKATILLQAVYRGQQVRKEVGRWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRTDRRNFLNMKCSAVVLQAAFRGHRVRTDVANMHSAAVVIQANFRRFREQKTFRRRRWAAVVLQQRFRAQKQKQHAVKQYYKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMAAKK-------------------QKSQYQQIRKATILLQAVYRGQQVRKEVGRWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRTDRRNFLNMKCSAVVLQAAFRGHRVRTDVANMHSAALVIQANFRRFREQKTFRRRRWAAVVLQQRFRAQKQKRHAVKQYHKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYLTLKASVLNIQRRYRANMAAETQKHQYQQIRKATILLQAVYRGQQVRKEVGHWHQAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRRDRRNFLRMKRSAVVLQAAFRGYRVRTDVANMHSAAVVIQSNFRRFREQKTFRRRRWAAVVLQQRFRAQKQKRHAVKQYHKVRKAAVLLQAAYRGMKSRRILQQEHQAAAVIQRSFRAHCEHRSYVTLKASVLNIQRRYRANMAAKTQKHQYQQIRKATILLQAVYRGQQVRKDVGHWHRAATVIQSAFRRYREEVKFQAMRLSATIIQRRYRALLQGRTDRRNFLRMKRSAVVLQAAFRGHRVRTDVANMHSAALVIQANFRRFREQKTFRRRRWAAVVLQQRFRAQKQKQNAVKQYHKIRKAVVLLQAAYRGMKSR----------RILQQEH-----QAAAVIQRSFRAHCEHRSYLTLKSSVLKIQRRYRANMAAKTQKHQYQQIRKATILLQAVYRGQQVR 2969
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Medaka
Match: myo5ab (unconventional myosin-Va [Source:NCBI gene;Acc:101173462]) HSP 1 Score: 80.1073 bits (196), Expect = 3.459e-14 Identity = 50/151 (33.11%), Postives = 89/151 (58.94%), Query Frame = 1
Query: 3304 YLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQ--KFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQI--ILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQK 3744
YL + + K+R + + IQK R AR+++L R+ I +QKY + HQ R+ FL+ +TIQ N+R L+R+RY++ + A I IQ R+ K+Q +L Q A ++QK+ + ++ K+ +R+ +V ++Q RR+ +K+ +K
Sbjct: 753 YLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRK 903 HSP 2 Score: 71.2478 bits (173), Expect = 1.746e-11 Identity = 60/239 (25.10%), Postives = 113/239 (47.28%), Query Frame = 1
Query: 2179 CQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK--KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNL--RKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNL 2883
C+ ++++ + + K+ I + YL ++R +K++ A V +Q R +L ++ YLK RS++ IQKY +G+ AR+ F++ T+A V IQ R + +R+ Y + AA+ IQS R+ + ++ Y L + +IIQK V L K+ + L + +++Q +R ++ K K +EH+ + + M N ++ LQ+ L
Sbjct: 723 CKDLLEKLIKNQEKYQFGKNKIFFRAGQVAYLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVI-----------------------TIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHF------KNLNVGMENKIVQLQQKL 932 HSP 3 Score: 67.3958 bits (163), Expect = 2.707e-10 Identity = 46/138 (33.33%), Postives = 75/138 (54.35%), Query Frame = 1
Query: 5590 RLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQS--ITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNL--SIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVK 5991
+L+ K+ V IQK IR + R ++L ++S+I IQ + R H + ++Q+ IQ N R ++ RKR+L+ +S I IQ R +AK+ Y + L + +Q VRG LAK Y++ A +L+Q V+
Sbjct: 756 KLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVR 893 HSP 4 Score: 67.0106 bits (162), Expect = 3.340e-10 Identity = 53/201 (26.37%), Postives = 103/201 (51.24%), Query Frame = 1
Query: 5236 YISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQK-----NFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKF--KMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQL-MKQSITVIQKNCRKFIARKRFLE 5814
Y+ + R +L+++ + IQK R + RKY+K +++VI IQK RR+ + F A++ IQ N R ++ RK + +KR + IQS +R ++ ++ + + +IIQK +RG + Y++ + VV +Q +R + +K +++ F ++ +N + ++Q + QK ++F R LE
Sbjct: 753 YLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVD---FLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHFKNLNVGMENKIVQLQQKLNEQQKENKEFSERLSVLE 950 HSP 5 Score: 64.6994 bits (156), Expect = 1.518e-9 Identity = 43/131 (32.82%), Postives = 76/131 (58.02%), Query Frame = 1
Query: 4510 LAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSH--FICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKL--RSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRR 4890
LA IQK R +L R++ + +++V IQ + R H R + F+ Q AA+ +Q N+R +L RK + + R+ I +QS+++ +A++ Y KL ++I+QK RG+ A + + + A + +Q VRR
Sbjct: 764 LACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRR 894 HSP 6 Score: 63.929 bits (154), Expect = 2.999e-9 Identity = 48/161 (29.81%), Postives = 75/161 (46.58%), Query Frame = 1
Query: 3853 GYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRK--IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNET--RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQ 4323
Y + + R + + IQ + RC++ R+ +L + S I IQKY RG R+ + QT A IQ N+R +L RK ++ KR+AAI IQ R H +QQY + +K + IQ +R ++A Q Y++ A +Q
Sbjct: 752 AYLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLE-----------------------RKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQ 889 HSP 7 Score: 62.7734 bits (151), Expect = 5.447e-9 Identity = 42/140 (30.00%), Postives = 82/140 (58.57%), Query Frame = 1
Query: 2140 LKKFKSIKMRI--IICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCR--IRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRI--RKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFR 2541
L+K +S K+R+ + Q ++ +LAR + K ++S I IQK R + R + + + A V +Q + R +L +K YL+ + + IQ+ +R ++ + Y ++ + IIQK+V+G+LA++ + + A+V++QS R
Sbjct: 754 LEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVR 893 HSP 8 Score: 61.6178 bits (148), Expect = 1.507e-8 Identity = 52/166 (31.33%), Postives = 80/166 (48.19%), Query Frame = 1
Query: 4921 RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIR--AHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRL--KMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLK 5406
R A + IQK +R +L R RKYL RR + IQ + RG+ R FL Q + VTIQ + +L RK+YL+ R I IQ ++R ++++ ++ +L + +IIQK RG+ + Y + AV+ +Q RR K + LK
Sbjct: 763 RLACVSIQKTIRCWLAR-----------------RKYLKTRR------SVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLK 905 HSP 9 Score: 61.2326 bits (147), Expect = 1.844e-8 Identity = 44/138 (31.88%), Postives = 79/138 (57.25%), Query Frame = 1
Query: 3415 IVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYI---KNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKM--KESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQK 3813
+ +QK I+ R+K+LK + VITIQK R Q RRY+ + +A + IQ R E+K+ + AA +Q ++++ K+Q+ K+ ++ +IQK+ R + ++ +++ + V+LLQS +R I KK +K
Sbjct: 767 VSIQKTIRCWLARRKYLKTRRSVITIQKYTRG-HQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRK 903 HSP 10 Score: 60.8474 bits (146), Expect = 2.538e-8 Identity = 51/194 (26.29%), Postives = 90/194 (46.39%), Query Frame = 1
Query: 3025 ALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKL--KSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQI 3600
A +++ + LR A + IQKT RC+ R+K YLK ++SV+ IQK+T+G R+Y+ +L+ ++ + IQ + R RK++L R I +Q ++ H +Q++ KL + + + IQK +R L ++ Y + AV+ +Q R K KK++
Sbjct: 752 AYLEKLRSDKLRLACVSIQKTIRCWLARRK-----------------------YLKTRRSVITIQKYTRGH------------------QARRYV---DFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKEL 901 HSP 11 Score: 60.077 bits (144), Expect = 3.582e-8 Identity = 48/141 (34.04%), Postives = 76/141 (53.90%), Query Frame = 1
Query: 5548 ATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVR--TRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRF--LEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMR 5958
A + IQK IR R KY K + V+ IQK R + R FL ++ + IQ RM E K Y + + IQ R +A++++ L + +IIQK+ R +LAK+ Y+R L+ ++ +QS VR AK + +K++
Sbjct: 765 ACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLK 905 HSP 12 Score: 58.9214 bits (141), Expect = 1.016e-7 Identity = 55/250 (22.00%), Postives = 113/250 (45.20%), Query Frame = 1
Query: 3616 AATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRK--QFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHF------------------YRSYKIRKNF-----ICKRNAAIVIQKQFRK-HYIRQQYNETRKKVIFIQSLIRQFIAIQK 4287
A +QK + ++ ++++ K + SV IQKY R R+ F ++ + + +Q +RM + +KRY +K +A + I ++ + A+++Y Y+ +F + A++IQK++RG++ ++ Y A+ ++Q +R +K L A ++HF K K F + ++ + ++Q R+ +R+ ETR K + SL+ Q +Q+
Sbjct: 765 ACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQY------------------YKLLF---EQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHFKNLNVGMENKIVQLQQKLNEQQKENKEFSERLSVLEKTLTLERERQSREIESLRRSEEETRAKAETVPSLLEQLSFLQQ 993 HSP 13 Score: 55.8398 bits (133), Expect = 7.641e-7 Identity = 38/138 (27.54%), Postives = 76/138 (55.07%), Query Frame = 1
Query: 2104 IIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRIS--KMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIY--RSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKL 2505
+ +Q +R +L +K+ + +I Q + + AR + + ++A+ IQ N R +L R RY + +SA + +QS R ++ ++ Y K+ + +IIQ +RG+L + +Y+R + ++Q V+ A+K+ KL
Sbjct: 767 VSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKL 904 HSP 14 Score: 55.0694 bits (131), Expect = 1.287e-6 Identity = 47/147 (31.97%), Postives = 76/147 (51.70%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRK--IFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRG 6363
L KL+ K+R A + IQKT++ + R+ Y ++SVI +Q++ RG R+ FL+ A++ I +VR L R + L+KR A+I IQ+ R ++ K++Y Y LL +Q+ AV+IQ+ RG
Sbjct: 754 LEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRY--------------LQKR-SAAIAIQSMLRAHMAKQQY-----YKLLFEQK---------AVIIQKWVRG 871 HSP 15 Score: 54.6842 bits (130), Expect = 1.561e-6 Identity = 44/154 (28.57%), Postives = 75/154 (48.70%), Query Frame = 1
Query: 4726 ILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHK--KFLKLKNASICIQKNVRRYCQMKLYRDTRNASI-------------------------VIQKYVRGFLCRIKYQRQLLAAIILQ---RHFRKYLIIRRIDLEQKAARIIQNFYRG 5097
+ +Q ++ ++AR+ Y K R S I +QK RG A + FL+ A++ IQ NVR + + K Y R+A+I +IQK+VRG+L + Y+R L A ++LQ R + +R++ +E ++ +N G
Sbjct: 767 VSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHFKNLNVG 920 HSP 16 Score: 53.5286 bits (127), Expect = 3.470e-6 Identity = 49/176 (27.84%), Postives = 88/176 (50.00%), Query Frame = 1
Query: 4306 AATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHF--ICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFN 4827
A IQK + ++ R+KY+ RRS + IQK R + RR++ + R+ AA IQ R +L RKR + ++ A IQ+ RAH + + + + A+ +QK +RG+L ++++ T ++L+QS ++ A+K +KL+ + V+ F+ N
Sbjct: 765 ACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGH------------------QARRYV---DFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEH-FKNLN 918 HSP 17 Score: 53.5286 bits (127), Expect = 4.210e-6 Identity = 43/164 (26.22%), Postives = 82/164 (50.00%), Query Frame = 1
Query: 2719 SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK--QFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYL--RNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIK 3198
+C+ IQK IR ++ RR +LK + +V ++ Y G+ R+ FL+ + + +Q N+RM + +K ++ K+SA I IQ+ +RA + ++++ L A+IIQK R + ++ + + +++Q VR I +K K+K
Sbjct: 765 ACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRM-----------------------WLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLK 905
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Medaka
Match: myo5ab (unconventional myosin-Va [Source:NCBI gene;Acc:101173462]) HSP 1 Score: 79.7221 bits (195), Expect = 3.881e-14 Identity = 50/151 (33.11%), Postives = 89/151 (58.94%), Query Frame = 1
Query: 3304 YLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQ--KFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQI--ILNNQAATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRKQFQK 3744
YL + + K+R + + IQK R AR+++L R+ I +QKY + HQ R+ FL+ +TIQ N+R L+R+RY++ + A I IQ R+ K+Q +L Q A ++QK+ + ++ K+ +R+ +V ++Q RR+ +K+ +K
Sbjct: 753 YLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRK 903 HSP 2 Score: 71.2478 bits (173), Expect = 1.786e-11 Identity = 60/239 (25.10%), Postives = 113/239 (47.28%), Query Frame = 1
Query: 2179 CQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARK--KFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNL--RKSVIIIQKVVHKVLFKRKLEKRLRSCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRKQFLKMRNSVILLQKNL 2883
C+ ++++ + + K+ I + YL ++R +K++ A V +Q R +L ++ YLK RS++ IQKY +G+ AR+ F++ T+A V IQ R + +R+ Y + AA+ IQS R+ + ++ Y L + +IIQK V L K+ + L + +++Q +R ++ K K +EH+ + + M N ++ LQ+ L
Sbjct: 723 CKDLLEKLIKNQEKYQFGKNKIFFRAGQVAYLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVI-----------------------TIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHF------KNLNVGMENKIVQLQQKL 932 HSP 3 Score: 67.3958 bits (163), Expect = 2.656e-10 Identity = 46/138 (33.33%), Postives = 75/138 (54.35%), Query Frame = 1
Query: 5590 RLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQS--ITVIQKNCRKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNL--SIIIFVQSLVRGKLAKLKYQKMRTATILIQKTVK 5991
+L+ K+ V IQK IR + R ++L ++S+I IQ + R H + ++Q+ IQ N R ++ RKR+L+ +S I IQ R +AK+ Y + L + +Q VRG LAK Y++ A +L+Q V+
Sbjct: 756 KLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVR 893 HSP 4 Score: 66.6254 bits (161), Expect = 3.878e-10 Identity = 53/201 (26.37%), Postives = 103/201 (51.24%), Query Frame = 1
Query: 5236 YISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQK-----NFRRFSELKTFQNLKNASIIIQKNFRCYILRKEFKKKRKNCVKIQSYIRRYICISKF--KMIKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMHYEYKNYQL-MKQSITVIQKNCRKFIARKRFLE 5814
Y+ + R +L+++ + IQK R + RKY+K +++VI IQK RR+ + F A++ IQ N R ++ RK + +KR + IQS +R ++ ++ + + +IIQK +RG + Y++ + VV +Q +R + +K +++ F ++ +N + ++Q + QK ++F R LE
Sbjct: 753 YLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVD---FLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHFKNLNVGMENKIVQLQQKLNEQQKENKEFSERLSVLE 950 HSP 5 Score: 64.6994 bits (156), Expect = 1.553e-9 Identity = 43/131 (32.82%), Postives = 76/131 (58.02%), Query Frame = 1
Query: 4510 LAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSH--FICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKL--RSSSIIVQKIFRGFNAHKKFLKLKNASICIQKNVRR 4890
LA IQK R +L R++ + +++V IQ + R H R + F+ Q AA+ +Q N+R +L RK + + R+ I +QS+++ +A++ Y KL ++I+QK RG+ A + + + A + +Q VRR
Sbjct: 764 LACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRR 894 HSP 6 Score: 63.5438 bits (153), Expect = 3.452e-9 Identity = 48/161 (29.81%), Postives = 75/161 (46.58%), Query Frame = 1
Query: 3853 GYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRK--IYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNET--RKKVIFIQSLIRQFIAIQKYKQMKKAATYIQ 4323
Y + + R + + IQ + RC++ R+ +L + S I IQKY RG R+ + QT A IQ N+R +L RK ++ KR+AAI IQ R H +QQY + +K + IQ +R ++A Q Y++ A +Q
Sbjct: 752 AYLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLE-----------------------RKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQ 889 HSP 7 Score: 62.7734 bits (151), Expect = 5.482e-9 Identity = 42/140 (30.00%), Postives = 82/140 (58.57%), Query Frame = 1
Query: 2140 LKKFKSIKMRI--IICQSVVKRYLARHRISKMKKSAILIQKNYRRYLCR--IRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRI--RKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFR 2541
L+K +S K+R+ + Q ++ +LAR + K ++S I IQK R + R + + + A V +Q + R +L +K YL+ + + IQ+ +R ++ + Y ++ + IIQK+V+G+LA++ + + A+V++QS R
Sbjct: 754 LEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVR 893 HSP 8 Score: 61.2326 bits (147), Expect = 1.809e-8 Identity = 52/166 (31.33%), Postives = 80/166 (48.19%), Query Frame = 1
Query: 4921 RNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIR--AHFLCQKNSCVTIQNYFKAYLIRKKYLEIRQKTIFIQCLVRRYISRNRFLRL--KMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLK 5406
R A + IQK +R +L R RKYL RR + IQ + RG+ R FL Q + VTIQ + +L RK+YL+ R I IQ ++R ++++ ++ +L + +IIQK RG+ + Y + AV+ +Q RR K + LK
Sbjct: 763 RLACVSIQKTIRCWLAR-----------------RKYLKTRR------SVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLK 905 HSP 9 Score: 61.2326 bits (147), Expect = 1.935e-8 Identity = 44/138 (31.88%), Postives = 79/138 (57.25%), Query Frame = 1
Query: 3415 IVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYI---KNKKAVIFIQRKFRSCKEKKQIILNNQAATVVQKYFKSYICKKQFRKM--KESVTVIQKYQRRLICRKQFQKEMKLVILLQSKIRMIITKKRYQK 3813
+ +QK I+ R+K+LK + VITIQK R Q RRY+ + +A + IQ R E+K+ + AA +Q ++++ K+Q+ K+ ++ +IQK+ R + ++ +++ + V+LLQS +R I KK +K
Sbjct: 767 VSIQKTIRCWLARRKYLKTRRSVITIQKYTRG-HQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRK 903 HSP 10 Score: 60.4622 bits (145), Expect = 2.664e-8 Identity = 51/194 (26.29%), Postives = 90/194 (46.39%), Query Frame = 1
Query: 3025 ALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKL--KSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRSCKEKKQI 3600
A +++ + LR A + IQKT RC+ R+K YLK ++SV+ IQK+T+G R+Y+ +L+ ++ + IQ + R RK++L R I +Q ++ H +Q++ KL + + + IQK +R L ++ Y + AV+ +Q R K KK++
Sbjct: 752 AYLEKLRSDKLRLACVSIQKTIRCWLARRK-----------------------YLKTRRSVITIQKYTRGH------------------QARRYV---DFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKEL 901 HSP 11 Score: 60.077 bits (144), Expect = 3.545e-8 Identity = 48/141 (34.04%), Postives = 76/141 (53.90%), Query Frame = 1
Query: 5548 ATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIVR--TRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQKNCRKFIARKRF--LEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRGKLAKLKYQKMR 5958
A + IQK IR R KY K + V+ IQK R + R FL ++ + IQ RM E K Y + + IQ R +A++++ L + +IIQK+ R +LAK+ Y+R L+ ++ +QS VR AK + +K++
Sbjct: 765 ACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLK 905 HSP 12 Score: 58.5362 bits (140), Expect = 1.190e-7 Identity = 55/250 (22.00%), Postives = 113/250 (45.20%), Query Frame = 1
Query: 3616 AATVVQKYFKSYICKKQFRKMKESVTVIQKYQRRLICRK--QFQKEMKLVILLQSKIRMIITKKRYQKKIAATLTISKFVKGYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHF------------------YRSYKIRKNF-----ICKRNAAIVIQKQFRK-HYIRQQYNETRKKVIFIQSLIRQFIAIQK 4287
A +QK + ++ ++++ K + SV IQKY R R+ F ++ + + +Q +RM + +KRY +K +A + I ++ + A+++Y Y+ +F + A++IQK++RG++ ++ Y A+ ++Q +R +K L A ++HF K K F + ++ + ++Q R+ +R+ ETR K + SL+ Q +Q+
Sbjct: 765 ACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQY------------------YKLLF---EQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHFKNLNVGMENKIVQLQQKLNEQQKENKEFSERLSVLEKTLTLERERQSREIESLRRSEEETRAKAETVPSLLEQLSFLQQ 993 HSP 13 Score: 55.8398 bits (133), Expect = 8.091e-7 Identity = 38/138 (27.54%), Postives = 76/138 (55.07%), Query Frame = 1
Query: 2104 IIVQSIVRRFLCLKKFKSIKMRIIICQSVVKRYLARHRIS--KMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIY--RSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKL 2505
+ +Q +R +L +K+ + +I Q + + AR + + ++A+ IQ N R +L R RY + +SA + +QS R ++ ++ Y K+ + +IIQ +RG+L + +Y+R + ++Q V+ A+K+ KL
Sbjct: 767 VSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKL 904 HSP 14 Score: 55.0694 bits (131), Expect = 1.374e-6 Identity = 47/147 (31.97%), Postives = 76/147 (51.70%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRK--IFLKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRYCLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRG 6363
L KL+ K+R A + IQKT++ + R+ Y ++SVI +Q++ RG R+ FL+ A++ I +VR L R + L+KR A+I IQ+ R ++ K++Y Y LL +Q+ AV+IQ+ RG
Sbjct: 754 LEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRY--------------LQKR-SAAIAIQSMLRAHMAKQQY-----YKLLFEQK---------AVIIQKWVRG 871 HSP 15 Score: 54.6842 bits (130), Expect = 1.724e-6 Identity = 44/154 (28.57%), Postives = 75/154 (48.70%), Query Frame = 1
Query: 4726 ILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHK--KFLKLKNASICIQKNVRRYCQMKLYRDTRNASI-------------------------VIQKYVRGFLCRIKYQRQLLAAIILQ---RHFRKYLIIRRIDLEQKAARIIQNFYRG 5097
+ +Q ++ ++AR+ Y K R S I +QK RG A + FL+ A++ IQ NVR + + K Y R+A+I +IQK+VRG+L + Y+R L A ++LQ R + +R++ +E ++ +N G
Sbjct: 767 VSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHFKNLNVG 920 HSP 16 Score: 53.5286 bits (127), Expect = 3.675e-6 Identity = 49/176 (27.84%), Postives = 88/176 (50.00%), Query Frame = 1
Query: 4306 AATYIQKIAKGYIIRKKYVTQRRSAVIIQKNVRQYLXXXXXXXXXXXXXXXXXYVRRFLMRSVYKRKLLAATLIQKIARGYLVRKRIVVEQKAVRIIQNFYRAHTIRSHF--ICQKNAAIKLQKNIRGYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFN 4827
A IQK + ++ R+KY+ RRS + IQK R + RR++ + R+ AA IQ R +L RKR + ++ A IQ+ RAH + + + + A+ +QK +RG+L ++++ T ++L+QS ++ A+K +KL+ + V+ F+ N
Sbjct: 765 ACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGH------------------QARRYV---DFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEH-FKNLN 918 HSP 17 Score: 53.1434 bits (126), Expect = 4.849e-6 Identity = 43/164 (26.22%), Postives = 82/164 (50.00%), Query Frame = 1
Query: 2719 SCIIIQKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK--QFLKMRNSVILLQKNLRMLSLRNSFLXXXXXXXXXXXXXXRYFAKKEFVAKKSATILIQTKVRALIQRRKFQYL--RNAAIIIQKTFRCYSVRKKFLIQYYSAIVIQKNVRSIICQKNYLKIK 3198
+C+ IQK IR ++ RR +LK + +V ++ Y G+ R+ FL+ + + +Q N+RM + +K ++ K+SA I IQ+ +RA + ++++ L A+IIQK R + ++ + + +++Q VR I +K K+K
Sbjct: 765 ACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRM-----------------------WLERKRYLQKRSAAIAIQSMLRAHMAKQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLK 905
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Medaka
Match: myo5c (myosin VC [Source:NCBI gene;Acc:101162444]) HSP 1 Score: 71.633 bits (174), Expect = 1.306e-11 Identity = 47/176 (26.70%), Postives = 95/176 (53.98%), Query Frame = 1
Query: 2179 CQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTK-----------IIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKA--AVIIQSFYRSSVCRRTYLNLRKSVIIIQ 2667
C+ V++R + K ++ I + YL ++R ++++ A V++Q HFR + ++ YL+I + +++Q IRG K IRK+ +IQ++ +GY R+ + + +A + IQ+ RG+ R+ Y ++A A+I+Q + R+ + RR + +R+ V+ +Q
Sbjct: 570 CKCVLQRLIHDTNQYKFGRTKIFFRAGQVAYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRG------QKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQ 739 HSP 2 Score: 66.6254 bits (161), Expect = 3.568e-10 Identity = 50/160 (31.25%), Postives = 89/160 (55.62%), Query Frame = 1
Query: 3304 YLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRS-C-KEKKQIILNNQAATVVQKYFKSYICKKQFRKMKES--VTVIQKYQRRLICRKQFQKEMKLVILLQ 3771
YL + + ++R++ +IIQKHFRA S R+++L R IV+Q+YI+ + TI+K + A +K A + IQR +R C ++ Q + QA +Q + + ++ +KQ++KM E+ ++QKY R + R++FQ +LV+ +Q
Sbjct: 600 YLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQK-------------TIRKTVTA-----EALKQGWAAVVIQRHWRGYCMRQIYQAVC--QATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQ 739 HSP 3 Score: 64.6994 bits (156), Expect = 1.430e-9 Identity = 49/153 (32.03%), Postives = 89/153 (58.17%), Query Frame = 1
Query: 3025 ALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVI------QKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKS--TIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQK 3459
A +++ + LR A +IIQK FR +S R+K+L +AIV+ QK +R + + LK + +VIQ+H +G+ +++ Y+ + I Q+ R ++ +KQY K+ ++ +I+QK+ RA AR++F R+ + VQ ++ Q R+K
Sbjct: 599 AYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAE-ALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQQLRKK 750 HSP 4 Score: 60.8474 bits (146), Expect = 2.564e-8 Identity = 42/150 (28.00%), Postives = 80/150 (53.33%), Query Frame = 1
Query: 4681 GYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKK-----FLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLA--AIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIR 5109
YL + R +++Q + + R+ Y ++R ++I++Q+ RG +K LK A++ IQ++ R YC ++Y+ A+I IQ + RG++ R +Y++ + A A+ILQ++ R +L RR Q R++ N Y ++
Sbjct: 599 AYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRF---QTMRRLVLNVQLSYRVQ 745 HSP 5 Score: 60.077 bits (144), Expect = 3.560e-8 Identity = 50/182 (27.47%), Postives = 88/182 (48.35%), Query Frame = 1
Query: 3853 GYFARKKYLSYRHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKA--ATYIQKIAKGYIIRKKYVTQRRSAVIIQ 4392
Y + + R + ++IQ FR + R+ +L I+ +AIV+Q+Y+RG QK IR KT+ + L Q + AA+VIQ+ +R + +RQ Y + I IQ+ R ++A ++YK+M +A A +QK + ++ R+++ T RR + +Q
Sbjct: 599 AYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRG-----------------QKTIR-----KTVTAE----ALKQGW---------------AAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQ 739 HSP 6 Score: 58.9214 bits (141), Expect = 7.786e-8 Identity = 39/130 (30.00%), Postives = 69/130 (53.08%), Query Frame = 1
Query: 5788 FIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRG-----KLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLKNA--SIIISKHVRGVLVRNHFQ 6156
++ + R ++ +IIQK FR + +R Y R I +Q +RG K + K A ++IQ+ +GY +R+ Y+ + ++ I +Q F RG++ RK + K+ A ++I+ K+ R L R FQ
Sbjct: 600 YLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQ 729 HSP 7 Score: 58.9214 bits (141), Expect = 8.120e-8 Identity = 52/198 (26.26%), Postives = 101/198 (51.01%), Query Frame = 1
Query: 5155 YFKAYLIRKKYLE--IRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCY-ILRK----EFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL--VVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMH 5721
++ Y I +LE +R K +C+++R I + + I + Y + + ++A + IQK+FR +S+ + + +++A+I++Q+ R +RK E K+ V IQ + R Y ++ + AT+ IQ RG R +YKK+++ + +QK RA + R RF +++ ++N+Q YR+
Sbjct: 548 FYSRYSILMSHLEADVRDKKETCKCVLQRLIHDTNQYKFGRTKIFFRAGQVAYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQ 745 HSP 8 Score: 58.9214 bits (141), Expect = 8.613e-8 Identity = 44/152 (28.95%), Postives = 83/152 (54.61%), Query Frame = 1
Query: 4846 KLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRA--HFLCQKNSCVTIQNYFKAYLIRKKYLEIRQ--KTIFIQCLVRRYISRNRFLRLKMSVIIIQ 5289
+L+ A + IQK+ R + Q + Y R+A+IV+Q+Y+RG K R+ + A L++ + AA +IQ +RGY +R +CQ + +TIQ + + ++ RK+Y ++ + K + +Q R +++R RF ++ V+ +Q
Sbjct: 608 RLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRG----QKTIRKTVTAEALKQGW--------------AAVVIQRHWRGYCMRQIYQAVCQ--ATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQ 739 HSP 9 Score: 56.225 bits (134), Expect = 5.816e-7 Identity = 53/201 (26.37%), Postives = 101/201 (50.25%), Query Frame = 1
Query: 2329 FRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAK-RRNYTI----QIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRS--CIIIQKYIRGFINRRNFLKFKSAV-NILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNS 2907
+R + N K R+ + + YL + R+R++ IIQK+ + + R+K++++ A +V+Q RG R+ T Q AAV+IQ +R R+ Y + ++ I IQ + +++ +K + + +I+QKY R ++ RR F + V N+ Y + LR+K + + + L++K + +L NS
Sbjct: 574 LQRLIHDTNQYKFGRTKIFFRAGQVAYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQQLRKKIEEQTKENRGLMEK---LTTLANS 771 HSP 10 Score: 53.9138 bits (128), Expect = 2.666e-6 Identity = 53/180 (29.44%), Postives = 88/180 (48.89%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGF-LIRKIF----LKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY---------CLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHEISEIRN 6426
L KL+ ++R A ++IQK + + R+ Y ++ + I LQ++IRG IRK LK A+++I +H RG +R +Q Q A+I IQA+ R ++ +++Y +L+ YT R RF ++R + +Q +R +QLR KKI + E R
Sbjct: 601 LEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQ---------------ATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQQLR-----KKIEEQTKENRG 760
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Medaka
Match: myo5c (myosin VC [Source:NCBI gene;Acc:101162444]) HSP 1 Score: 71.633 bits (174), Expect = 1.377e-11 Identity = 47/176 (26.70%), Postives = 95/176 (53.98%), Query Frame = 1
Query: 2179 CQSVVKRYLARHRISKMKKSAILIQKNYRRYLCRIRYEKIKSATVVLQSHFRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTK-----------IIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKA--AVIIQSFYRSSVCRRTYLNLRKSVIIIQ 2667
C+ V++R + K ++ I + YL ++R ++++ A V++Q HFR + ++ YL+I + +++Q IRG K IRK+ +IQ++ +GY R+ + + +A + IQ+ RG+ R+ Y ++A A+I+Q + R+ + RR + +R+ V+ +Q
Sbjct: 586 CKCVLQRLIHDTNQYKFGRTKIFFRAGQVAYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRG------QKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQ 755 HSP 2 Score: 66.6254 bits (161), Expect = 3.576e-10 Identity = 50/160 (31.25%), Postives = 89/160 (55.62%), Query Frame = 1
Query: 3304 YLLQKQYLKVRKSTIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQKFLKLKSQVITIQKNIRALLQRRRYIKNKKAVIFIQRKFRS-C-KEKKQIILNNQAATVVQKYFKSYICKKQFRKMKES--VTVIQKYQRRLICRKQFQKEMKLVILLQ 3771
YL + + ++R++ +IIQKHFRA S R+++L R IV+Q+YI+ + TI+K + A +K A + IQR +R C ++ Q + QA +Q + + ++ +KQ++KM E+ ++QKY R + R++FQ +LV+ +Q
Sbjct: 616 YLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQK-------------TIRKTVTA-----EALKQGWAAVVIQRHWRGYCMRQIYQAVC--QATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQ 755 HSP 3 Score: 64.6994 bits (156), Expect = 1.421e-9 Identity = 49/153 (32.03%), Postives = 89/153 (58.17%), Query Frame = 1
Query: 3025 ALIQRRKFQYLRNAAIIIQKTFRCYSVRKKFLIQYYSAIVI------QKNVRSIICQKNYLKIKQSVLVIQKHTKGFLVXXXXXXXXXXXXXCQSLVRKYLLQKQYLKVRKS--TIIIQKHFRAISARKQFLNFRKFTIVVQKYIKMHQCRQK 3459
A +++ + LR A +IIQK FR +S R+K+L +AIV+ QK +R + + LK + +VIQ+H +G+ +++ Y+ + I Q+ R ++ +KQY K+ ++ +I+QK+ RA AR++F R+ + VQ ++ Q R+K
Sbjct: 615 AYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAE-ALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQQLRKK 766 HSP 4 Score: 60.8474 bits (146), Expect = 2.547e-8 Identity = 42/150 (28.00%), Postives = 80/150 (53.33%), Query Frame = 1
Query: 4681 GYLIRKNFTETRNKIILVQSLMKGFIARKCYQKLRSSSIIVQKIFRGFNAHKK-----FLKLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLA--AIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIR 5109
YL + R +++Q + + R+ Y ++R ++I++Q+ RG +K LK A++ IQ++ R YC ++Y+ A+I IQ + RG++ R +Y++ + A A+ILQ++ R +L RR Q R++ N Y ++
Sbjct: 615 AYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRF---QTMRRLVLNVQLSYRVQ 761 HSP 5 Score: 60.077 bits (144), Expect = 3.783e-8 Identity = 49/171 (28.65%), Postives = 85/171 (49.71%), Query Frame = 1
Query: 3886 RHSVIVIQNSFRCFMYRKMFLSIKFSAIVIQKYLRGFIKRKIYCSQTTAIKVIQKNIRGFLVRKTLNSHHQSATLIQHFYRSYKIRKNFICKRNAAIVIQKQFRKHYIRQQYNETRKKVIFIQSLIRQFIAIQKYKQMKKA--ATYIQKIAKGYIIRKKYVTQRRSAVIIQ 4392
R + ++IQ FR + R+ +L I+ +AIV+Q+Y+RG QK IR KT+ + L Q + AA+VIQ+ +R + +RQ Y + I IQ+ R ++A ++YK+M +A A +QK + ++ R+++ T RR + +Q
Sbjct: 626 REACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRG-----------------QKTIR-----KTVTAE----ALKQGW---------------AAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQ 755 HSP 6 Score: 59.3066 bits (142), Expect = 7.170e-8 Identity = 39/130 (30.00%), Postives = 69/130 (53.08%), Query Frame = 1
Query: 5788 FIARKRFLEIKSNIIIIQKFFRRFLAKRSYQRNLSIIIFVQSLVRG-----KLAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGFLIRKIFLKLKNA--SIIISKHVRGVLVRNHFQ 6156
++ + R ++ +IIQK FR + +R Y R I +Q +RG K + K A ++IQ+ +GY +R+ Y+ + ++ I +Q F RG++ RK + K+ A ++I+ K+ R L R FQ
Sbjct: 616 YLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQ 745 HSP 7 Score: 58.9214 bits (141), Expect = 8.272e-8 Identity = 52/198 (26.26%), Postives = 101/198 (51.01%), Query Frame = 1
Query: 5155 YFKAYLIRKKYLE--IRQKTIFIQCLVRRYISRNRFLRLKMSVIIIQKVTRGYFTHRKYVKQKKAVINIQKNFRRFSELKTFQNLKNASIIIQKNFRCY-ILRK----EFKKKRKNCVKIQSYIRRYICISKFKMIKSATLIIQKHIRGIFVRLKYKKIIKL--VVFIQKNIRANIVRTRFLNIKKSIINIQSFYRMH 5721
++ Y I +LE +R K +C+++R I + + I + Y + + ++A + IQK+FR +S+ + + +++A+I++Q+ R +RK E K+ V IQ + R Y ++ + AT+ IQ RG R +YKK+++ + +QK RA + R RF +++ ++N+Q YR+
Sbjct: 564 FYSRYSILMSHLEADVRDKKETCKCVLQRLIHDTNQYKFGRTKIFFRAGQVAYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQ 761 HSP 8 Score: 58.9214 bits (141), Expect = 8.342e-8 Identity = 44/152 (28.95%), Postives = 83/152 (54.61%), Query Frame = 1
Query: 4846 KLKNASICIQKNVRRYCQMKLYRDTRNASIVIQKYVRGFLCRIKYQRQLLAAIILQRHFRKYLIIRRIDLEQKAARIIQNFYRGYTIRA--HFLCQKNSCVTIQNYFKAYLIRKKYLEIRQ--KTIFIQCLVRRYISRNRFLRLKMSVIIIQ 5289
+L+ A + IQK+ R + Q + Y R+A+IV+Q+Y+RG K R+ + A L++ + AA +IQ +RGY +R +CQ + +TIQ + + ++ RK+Y ++ + K + +Q R +++R RF ++ V+ +Q
Sbjct: 624 RLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRG----QKTIRKTVTAEALKQGW--------------AAVVIQRHWRGYCMRQIYQAVCQ--ATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQ 755 HSP 9 Score: 56.225 bits (134), Expect = 5.538e-7 Identity = 53/201 (26.37%), Postives = 101/201 (50.25%), Query Frame = 1
Query: 2329 FRRYLVQKNYLKIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAK-RRNYTI----QIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKRKLEKRLRS--CIIIQKYIRGFINRRNFLKFKSAV-NILEHYFMGYLRRKQFLKMRNSVILLQKNLRMLSLRNS 2907
+R + N K R+ + + YL + R+R++ IIQK+ + + R+K++++ A +V+Q RG R+ T Q AAV+IQ +R R+ Y + ++ I IQ + +++ +K + + +I+QKY R ++ RR F + V N+ Y + LR+K + + + L++K + +L NS
Sbjct: 590 LQRLIHDTNQYKFGRTKIFFRAGQVAYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQQLRKKIEEQTKENRGLMEK---LTTLANS 787 HSP 10 Score: 53.9138 bits (128), Expect = 2.693e-6 Identity = 53/180 (29.44%), Postives = 88/180 (48.89%), Query Frame = 1
Query: 5929 LAKLKYQKMRTATILIQKTVKGYFIRKHYKILQKSVIQLQRFIRGF-LIRKIF----LKLKNASIIISKHVRGVLVRNHFQKNKQHMKIFAQENLRKRLEASIKIQAYFRCYIQKRRY---------CLLKSYTLLIQQRWRFIVLKRSAVVIQRIWRGRQLRCHLNAKKIGHEISEIRN 6426
L KL+ ++R A ++IQK + + R+ Y ++ + I LQ++IRG IRK LK A+++I +H RG +R +Q Q A+I IQA+ R ++ +++Y +L+ YT R RF ++R + +Q +R +QLR KKI + E R
Sbjct: 617 LEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQ---------------ATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQQLR-----KKIEEQTKENRG 776
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 61.6178 bits (148), Expect = 1.007e-8 Identity = 54/160 (33.75%), Postives = 86/160 (53.75%), Query Frame = 1
Query: 2362 KIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKR-KLEKRLRSCIII-QKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK 2835
KI S+ +IQ+ +RG + R Y I K T IQ Y++ LA +K KL+ QI+A +IIQSFYR + R+ ++ ++ +V+ I+K K++ R K + +C+II Q +R FI RR FLK + V +++++ Y RRK
Sbjct: 773 KIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLS---------------------QIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNH---YRRRK 908 HSP 2 Score: 52.7582 bits (125), Expect = 5.467e-6 Identity = 57/175 (32.57%), Postives = 87/175 (49.71%), Query Frame = 1
Query: 5539 IKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIV---RTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQK-----------------NC--------RKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQ------RNLSIIIFVQSLVRGKLAKLKYQKMRT 5961
I+S+ +IQ +RG R +Y I KL V IQ IR + T+ I+ II IQSFYRM+ K + MK ++ I+K NC R+FI R++FL+I+ +I+IQ +RR AK + + R+++ I FV + K+ +L QK+ T
Sbjct: 774 IESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVII-IQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELT-QKLDT 946
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 61.6178 bits (148), Expect = 1.040e-8 Identity = 54/160 (33.75%), Postives = 86/160 (53.75%), Query Frame = 1
Query: 2362 KIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKR-KLEKRLRSCIII-QKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK 2835
KI S+ +IQ+ +RG + R Y I K T IQ Y++ LA +K KL+ QI+A +IIQSFYR + R+ ++ ++ +V+ I+K K++ R K + +C+II Q +R FI RR FLK + V +++++ Y RRK
Sbjct: 769 KIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLS---------------------QIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNH---YRRRK 904 HSP 2 Score: 52.373 bits (124), Expect = 5.600e-6 Identity = 57/175 (32.57%), Postives = 87/175 (49.71%), Query Frame = 1
Query: 5539 IKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIV---RTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQK-----------------NC--------RKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQ------RNLSIIIFVQSLVRGKLAKLKYQKMRT 5961
I+S+ +IQ +RG R +Y I KL V IQ IR + T+ I+ II IQSFYRM+ K + MK ++ I+K NC R+FI R++FL+I+ +I+IQ +RR AK + + R+++ I FV + K+ +L QK+ T
Sbjct: 770 IESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVII-IQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELT-QKLDT 942
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 61.6178 bits (148), Expect = 1.041e-8 Identity = 54/160 (33.75%), Postives = 86/160 (53.75%), Query Frame = 1
Query: 2362 KIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKR-KLEKRLRSCIII-QKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK 2835
KI S+ +IQ+ +RG + R Y I K T IQ Y++ LA +K KL+ QI+A +IIQSFYR + R+ ++ ++ +V+ I+K K++ R K + +C+II Q +R FI RR FLK + V +++++ Y RRK
Sbjct: 769 KIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLS---------------------QIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNH---YRRRK 904 HSP 2 Score: 52.373 bits (124), Expect = 5.700e-6 Identity = 57/175 (32.57%), Postives = 87/175 (49.71%), Query Frame = 1
Query: 5539 IKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIV---RTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQK-----------------NC--------RKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQ------RNLSIIIFVQSLVRGKLAKLKYQKMRT 5961
I+S+ +IQ +RG R +Y I KL V IQ IR + T+ I+ II IQSFYRM+ K + MK ++ I+K NC R+FI R++FL+I+ +I+IQ +RR AK + + R+++ I FV + K+ +L QK+ T
Sbjct: 770 IESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVII-IQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELT-QKLDT 942
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 61.6178 bits (148), Expect = 1.059e-8 Identity = 54/160 (33.75%), Postives = 86/160 (53.75%), Query Frame = 1
Query: 2362 KIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKR-KLEKRLRSCIII-QKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK 2835
KI S+ +IQ+ +RG + R Y I K T IQ Y++ LA +K KL+ QI+A +IIQSFYR + R+ ++ ++ +V+ I+K K++ R K + +C+II Q +R FI RR FLK + V +++++ Y RRK
Sbjct: 774 KIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLS---------------------QIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNH---YRRRK 909 HSP 2 Score: 52.373 bits (124), Expect = 5.702e-6 Identity = 57/175 (32.57%), Postives = 87/175 (49.71%), Query Frame = 1
Query: 5539 IKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIV---RTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQK-----------------NC--------RKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQ------RNLSIIIFVQSLVRGKLAKLKYQKMRT 5961
I+S+ +IQ +RG R +Y I KL V IQ IR + T+ I+ II IQSFYRM+ K + MK ++ I+K NC R+FI R++FL+I+ +I+IQ +RR AK + + R+++ I FV + K+ +L QK+ T
Sbjct: 775 IESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVII-IQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELT-QKLDT 947
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 61.6178 bits (148), Expect = 1.067e-8 Identity = 54/160 (33.75%), Postives = 86/160 (53.75%), Query Frame = 1
Query: 2362 KIYRSILIIQNNIRGYLCRSNYKRIRKSTKIIQKYVKGYLARKKFVKLTKAIVVIQSAFRGYAKRRNYTIQIKAAVIIQSFYRSSVCRRTYLNLRKSVIIIQKVVHKVLFKR-KLEKRLRSCIII-QKYIRGFINRRNFLKFKSAVNILEHYFMGYLRRK 2835
KI S+ +IQ+ +RG + R Y I K T IQ Y++ LA +K KL+ QI+A +IIQSFYR + R+ ++ ++ +V+ I+K K++ R K + +C+II Q +R FI RR FLK + V +++++ Y RRK
Sbjct: 774 KIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLS---------------------QIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNH---YRRRK 909 HSP 2 Score: 52.373 bits (124), Expect = 5.842e-6 Identity = 57/175 (32.57%), Postives = 87/175 (49.71%), Query Frame = 1
Query: 5539 IKSATLIIQKHIRGIFVRLKYKKIIKLVVFIQKNIRANIV---RTRFLNIKKSIINIQSFYRMHYEYKNYQLMKQSITVIQK-----------------NC--------RKFIARKRFLEIKSNIIIIQKFFRRFLAKRSYQ------RNLSIIIFVQSLVRGKLAKLKYQKMRT 5961
I+S+ +IQ +RG R +Y I KL V IQ IR + T+ I+ II IQSFYRM+ K + MK ++ I+K NC R+FI R++FL+I+ +I+IQ +RR AK + + R+++ I FV + K+ +L QK+ T
Sbjct: 775 IESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVII-IQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELT-QKLDT 947 The following BLAST results are available for this feature:
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Abnormal spindle-like microcephaly-associated protein homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30006065 ID=SMED30006065|Name=Abnormal spindle-like microcephaly-associated protein homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=7397bpback to top protein sequence of SMED30006065-orf-1 >SMED30006065-orf-1 ID=SMED30006065-orf-1|Name=SMED30006065-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2439bp MNKFDNELILKPFQSKCIIDFGEIIVGRSEIQYIYLINDFDFDQKLDIVKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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