Cubilin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30006027 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8Note: Hover over icons to view figure legend
Homology
BLAST of Cubilin vs. Ensembl Human
Match: CUBN (cubilin [Source:HGNC Symbol;Acc:HGNC:2548]) HSP 1 Score: 94.7449 bits (234), Expect = 6.600e-19 Identity = 167/742 (22.51%), Postives = 278/742 (37.47%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKD-NFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTL--TFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEW--HLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW------TRVIPRLSNGSCPGF 2396
G SP +P +YP + ++ + L F++E S C D L+IY FH P + + C P + S N + + F +D + + GF A++ + +T C + A +GEI SP YP S +C + R + R+ L+F DF+L QD C + + + S + R CG + SS N L+LR R QN GF+ +F RQ C I +S S + SP + C++ I + + L+FT+ L + C ++ I E L RY CG + + + TS + + L+ F GF + ++ ++ + G Y + G+ NSP Y + YP N C ++ + ++L FI FQ + C +D++ + E G + RYCG S P ++ +G TL F S+ +G GF A++ K+F + NI T +G + SP +P Y + +W +++A IL +I+ +C LRIY+G ++ + CGT + S+ S+ N + F +D +S +GF + W V+P ++ G+C GF
Sbjct: 1400 GSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHS-RCNFDVLEIY------------GGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLS----------INGRGFNASW-----QAVT--------GGCGGIFQAP---SGEIHSPNYPSPYRSNTDCSWVIRVDRN-HRVLLNFTDFDLEPQDS-CIMAYDGL-------SSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSR----------------QNRGFRAQF--------------RQ------ACGGHILTS--SFDTVSSPRFPANYPNNQNCSWI---IQAQPPLNHITLSFTHFEL--ERSTTCARDFVEILDGGHEDAPLRGRY-------------CGTD-MPHPITSFSSALTLR--FVSDSSISAGGFHTT--------VTASVSACGGTFYMAE-------GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDS------------QDCSRDFVEIRE------GNATGHLVGRYCGNSFP---LNYSSIVGHTLWVRFISDGSGSGTGFQATFM-----KIFGND---NIVGT--HGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQ----NCYYDKLRIYDGPSIHARLIGAYCGTQTE--SFSSTGNSLTFHFYSD-SSISGKGFLLEWFAVDAPDGVLPTIAPGACGGF 1981 HSP 2 Score: 92.4337 bits (228), Expect = 3.187e-18 Identity = 162/724 (22.38%), Postives = 257/724 (35.50%), Query Frame = 3
Query: 210 GILLSPNWP-GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQD--EMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYR-----GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSE--LCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
GI+ SP + YP D+ +Y S+++ + L F F++ S SC DYL IY + N S +P+LG+FCG P N+ S NN ++L F D G+K +F + YL +N ++ S G+ LNC++ + I L F F L + C ++V++ + DS++ + CG F SS N L ++ + DL +L+ GF +T D P YN + + I SP + + IC + + ++ + V++ L L C YL + + R++ CG+N S PV ++ + K SG + R + YQ + G + SP + + Y ++ C A N I L F V C D+L V + L +YCGT +P + SQ L L FKS++ + G Y+ I CG + G SP YPG Y ++ CEW L V+P R + F C L +Y+G N S CG D++I + +SSN + ++F D + F++ W
Sbjct: 3046 GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVV-PSTSCSHDYLAIY-------DGANTS-----DPLLGKFCGSKR---PPNVKSSNNSMLLVF----------KTDSFQTAKGWKMSF---------RQTLGPQQGCGGYLTGSNNTFASPDSDSN--GMYDKNLNCVWIIIAPVNKV-IHLTFNTFALEAASTRQRCLYDYVKLYDG---DSENANLAGTFCGSTVPAPFISSGNFLTVQFIS-------------DL---TLEREGFNATYTIMDM--PCGGTYN----------------ATWTPQNISSPNSSDPDVPFSICTW----VIDSPPHQQVKITVWALQLTSQD---CTQNYLQLQDS--PQGHGNSRFQ-----------FCGRN------ASAVPVFYSSMSTAMVIFK-----------------SGVVNRNSRMSFTYQIADCNRDYHKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSV------------ECRNDFLEVRNGSNSNSPLLG-----KYCGTLLPNPVFSQNNEL--YLRFKSDSVTSDRG----YEIIWTSS--PSGCGGTLYGDR--GSFTSPGYPGTYPNNTYCEWVL--VAPAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARR-PSAFRLTW 3621 HSP 3 Score: 83.1889 bits (204), Expect = 2.482e-15 Identity = 66/240 (27.50%), Postives = 105/240 (43.75%), Query Frame = 3
Query: 1593 SEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTD 2312
+E G+I SPF+ N YP +C++ +++I L F VF+ +S H C DY+ + + L + + ++YCGT IP + S L T S+ +G F+ K CG ++ ++ G I SP +P Y + C WH+ V P L F +F +E +C+N L +Y+ + CG S PS SS N + + F+TD
Sbjct: 818 GDELTGEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIG-------SSAH-----CETDYVEIG-----SSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHG--------FMAKFSAEDLACGEILTEST--GTIQSPGHPNVYPHGINCTWHI-LVQPNHLIHLMFETFHLE-FHYNCTNDYLEVYDTDSETSLGRYCG-KSIPPSLTSSGNSLMLVFVTD 1027 HSP 4 Score: 78.9518 bits (193), Expect = 4.866e-14 Identity = 164/713 (23.00%), Postives = 263/713 (36.89%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
G L P G + + VY+ + EQ+ +NF H ++ C+ D YIEV+ E +LG+ CG+ I H I S N + + F D + + K F+A + + +T G I SP +P + P C + + I L+F F + C ++VEI + L S N + CG S +N LY+ V SS +N GF KF+ D C + +S G I SPG C + + Q ++ L F +L E + C + YL +Y E + RY CGK+ +S N ++++ F +GF ++Y + + C Y + G SP + N YP+N C Y ++ ++I + F F E + T D+L + R+ G+ ++ + G+++P ++S L L FKS+ GF A + S CG N++++S G SP+YP Y C W L + S F L F F +E +C+ L +Y+G N ++LCG D P SS + + ++ TD +G RGF+
Sbjct: 717 GELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQ-----CQSDSSQNYIEVRD------------GETLLGKVCGNGT--ISH-IKSITNSVWIRFKIDASVE----------KASFRAVYQVACGDELTG--------------------EGVIRSPFFPNVYPGERTCRWTIHQPQSQV-ILLNFTVFEI-GSSAHCETDYVEIGSSSILGSPEN---KKYCGTDIPSFITSVYNFLYVTFV----------------KSSSTENHGFMAKFSAED-----------------LACGEILT---ESTGTIQSPGHPNVYPHGINCTWHIL----VQPNHLIHLMFETFHL-EFH-YNCTNDYLEVYDTDSETS--LGRY-------------CGKSIPPSLTSSGNSLMLV---FVTDSDLAYEGFLINYEAIS---------AATACLQDYTDD----LGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYT-----------DFLEI-----RDGGYEKSPLLGIFYGSNLPPTIISHSNKL--WLKFKSDQIDTRSGFSAYWDGS------STGCGGNLTTSS--GTFISPNYPMPYYHSSECYWWLKS-SHGSAFELEFKDFHLE-HHPNCTLDYLAVYDGPSSNSHLLTQLCG-DEKPPLIRSSGDSMFIKLRTDEGQQG-RGFK 1271 HSP 5 Score: 78.9518 bits (193), Expect = 5.076e-14 Identity = 148/642 (23.05%), Postives = 243/642 (37.85%), Query Frame = 3
Query: 429 PVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLG--FTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFN--VKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
P+LG F G +L P I+S +N + L F SD+ S GF A YW S L ++G++ SP YP + C + +S A L+F DF+L + C ++++ + + P S ++ +LCG + SS + ++++L G+ Q GFK ++ RQ C+ + +Q+ G + S G + CN+ T N +N+T+L C YL +Y +M RY CG + T+ + + +L L T V + ++GF++ + +G G E +G G +SP + N YP N C + I+L F + H C+ D L EI + + + + C P + Q S G + FK++ NG GF AS+Q + + CG + S G IHSP+YP Y S+ C W + V R +L FT F +E ++ + Y+G + + + CG + SS N + +RF + S+ RGF+
Sbjct: 1118 PLLGIFYGSNL---PPTIISHSNKLWLKFKSDQIDTRS----------GFSA------------YWDGSSTGCGGNLTTSSGTFI----SPNYPMPYYHSSECYWWLKSSHGSA-FELEFKDFHL-EHHPNCTLDYLAVYDGP---SSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQ----------------QGRGFKAEY--------------RQ------TCE-NVVIVNQTYGILESIGYPNPYSENQHCNWTIRAT--TGNT----VNYTFLAFDLEHHINCSTDYLELYDGPRQMG----RY-------------CGVDLPPPGSTTSSKLQVLLL--TDGVGRREKGFQMQWFV---YGCGG--------------ELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDV------------EYHSRCNFDVL---EIYGGPD--FHSPRIAQLCTQRSPENPM-QVSSTGNELAIRFKTDLSINGRGFNASWQAV------TGGCGGIFQAPS--GEIHSPNYPSPYRSNTDCSWVIR-VDRNHRVLLNFTDFDLEP-----QDSCIMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSG-PSRQNRGFR 1613 HSP 6 Score: 78.5666 bits (192), Expect = 5.570e-14 Identity = 162/721 (22.47%), Postives = 250/721 (34.67%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFS-----DKYEPLNALYNRQDHI----PGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFK--SNAHKNGPGFLASYQFIKKRK-----VFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD 2312
G + SPN+P Y + +V N +V LNF F++E + + Y + S +R L R CG + + + IVS N + L F S + Q GF+A F I S +SSP +P P+ NC + +++ L I L F F L ++ C +FVEI LD DA R CG S + L LR V SS+ GF T S + ++N + P EC I SS PG NR +QL+F L + +D C ++ I + +L+ RY CG ++ LN++ V G L RF+ D SGT G G + SPF+ YP NS+ Q+ ++ ++ + E +C+ D L + + + YCGT S G +LTF S++ +G GFL + + + CG + + ++ SP +P YS+ + C W + A P L S IE + ++C+ L I +G N Q + LCG + P S+ ++ +RF +D
Sbjct: 1519 GEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEP-----QDSCIMAYDGLSSTMSR------------LARTCGR--EQLANPIVSSGNSLFLRFQSGPSRQ----------NRGFRAQFRQACGGHILT------------------SSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFEL-ERSTTCARDFVEI-----LDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVS----------------DSSISAGGFHTTVTASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSS---------PG-NR-----------------------LQLSFISFQLEDSQD--CSRDFVEIREGN-ATGHLVGRY-------------CGNSF--------------PLNYSSIV-----GHTLWVRFISDGSGSGTGFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEE------------IQNCYYDKLRIYDGPS-----IHARLIGAYCGTQTESF-----SSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTIAPGACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQA--PDSTVELNILSLDIE-SHRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGP-IRSTGEYMFIRFTSD 2076 HSP 7 Score: 75.485 bits (184), Expect = 5.099e-13 Identity = 149/686 (21.72%), Postives = 232/686 (33.82%), Query Frame = 3
Query: 267 YVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIIN-----QPQLDSDSNDADNRLCG-IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRV 2297
+ G + ++FE FN++ S CEKD+++I+ S +LGR+CG++ IP +I + +N ++ F +D + S GF+ F E S G +SP YP P C + + RI L F + L C E V + N PQL+ +LC + + + SS N + + R Y GF +T S+ +L N EG SPG + + N + + Q + ++F L +D CQ + + +R + LCG + K + P + ++F R E GF Y F GI + G G+I SP Y N Y S + C A I L F F + H +C D +TV R G ++ +YCG S P + S L +TF S+ G GF A++ + CG S + G I SPH+P + + C W K I +F I C N+ ++++ G ++ L CG + P S+ F V
Sbjct: 2365 WHLQGLSGHYLTISFEDFNLQNSS-GCEKDFVEIWDNHTSGN-------------ILGRYCGNT---IPDSIDTSSNTAVVRFVTDGSVTAS----------GFRLRFESSMEECGGDLQGS----------------IGTFTSPNYPNPNPHGRICEWRITAPEG-RRITLMFNNLRLATHPS-CNNEHVIVFNGIRSNSPQLE--------KLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYG----------------GFTASYTSSEDAVCGGSLPN------------------TPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQD--CQ--------------FDVLEFRVGDADGPLMWRLCGPS--KPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSFTDCGGI-----------------QIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDI------------EPHTTCAWDSVTV-----RNGGSPESPIIGQYCGNSNPRTIQSGSNQL--VVTFNSDHSLQGGGFYATW------NTQTLGCGGIFHSDN--GTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAV 2901 HSP 8 Score: 75.0998 bits (183), Expect = 6.515e-13 Identity = 163/733 (22.24%), Postives = 264/733 (36.02%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMC-PVEFVEIINQPQLDSDSNDADN---RLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNF-YPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNV-KPQSE-LCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCP 2390
L SP WP Y V ++ + + V LN +IE +C D L I R +N+ VL CG IP I S + + F SD + + GF A+F H SC +HA+ G I+SP YP PS LNC + +S L I + F F + D C +++ + N P + S CG + F+S N+++++ + S + GFKIK+ + + L N + I +D S GY+ SP C + T+ +QL F E+ C YL E++ + ++ + CG + ++S ++ L F GFK Y S +C R G G++ S + Y N C++ S + + F ED + +S C +D++ + + N RYCG +IP + + + + F ++ GF ++ ++CG ++ + G SP+YP ICEW + A + R L F + ++ T SC+N + ++ G PQ E LC + + SS N ++V F TD S+ GF +T + GS P
Sbjct: 1991 LFSPGWPDSYSNRVDCTWLIQ-APDSTVELNILSLDIESHR-TCAYDSLVI---------RDGDNNLAQQLAVL---CGRE---IPGPIRSTGEYMFIRFTSDSSVT----------RAGFNASF----------------HKSCGGYLHAD---RGIITSPKYPETYPSNLNCSWHVLVQSGLT-IAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFIS----------------DHSNEGQGFKIKY----EAKSLACGGN-----------VYIHDAD-SAGYVTSPNHPHNYPPHADCIWILAAPPETR----IQLQFEDRFDIEVTP-NCTSNYL-------ELRDGVDSDAPILSK------FCGTSLPSSQWSSGE---VMYLRFRSDNSPTHVGFKAKY-------------SIAQCGGRVP----GQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISF------EDFNLQNSS------GCEKDFVEIWD------NHTSGNILGRYCGNTIPDSIDTSSNTA--VVRFVTDGSVTASGFRLRFESSM------EECGGDLQGS--IGTFTSPNYPNPNPHGRICEWRITAPEGR-RITLMFNNLRL-ATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTD-GSRPYGGFTASYTSSEDAVCGGSLP 2575 HSP 9 Score: 74.3294 bits (181), Expect = 1.207e-12 Identity = 101/408 (24.75%), Postives = 163/408 (39.95%), Query Frame = 3
Query: 1155 GYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP--GRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTS--KSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
GYIISP + C Y + + VV L F +L S + ++I+ Y + + P +CG + T PV+ LNF + GFK SYR + G+ + + S G+I SP Y+ YP++ C Y +++I L F F VP+ SC DYL + + + L ++CG+ P + S S+ L FK+++ + G+ S+ R+ Q G T SP G Y +L C W + ++P + I LTF +F +E S + C +++Y+G N CG+ P + SS NF+ V+F++D+T + GF +T
Sbjct: 2929 GYIISPNYPKQYDNNMNCTY----VIEANPLSVVLLTFVSFHLEARSAVT--------GSCVNDGVHIIRGYSVM---STPFATVCGDE-MPAPLTIAGPVL---LNFYSNEQITDFGFKFSYRIISCGGV-----------FNFSS------GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDV---VPST---------SCSHDYLAIYDGANTSDPLLG-----KFCGSKRPPNVKSSNNSM--LLVFKTDSFQTAKGWKMSF-----RQTLGPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWII--IAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGSTVPAP-FISSGNFLTVQFISDLTLE-REGFNATYT 3272 HSP 10 Score: 70.8626 bits (172), Expect = 1.399e-11 Identity = 167/724 (23.07%), Postives = 266/724 (36.74%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFE-HFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPD-QVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGT---DSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
+ G + SPN P YP +++ ++ L FE F+IE ++ +C +YL++ V S P+L +FCG SL P + S V+ L F SD N H +GFKA +S + C + I PT P L C + + S + + F DFNL Q C +FVEI + + S + R CG I D+ +S N +R V S+ GF+++F S + EC +Q S G SP + +IC + E ++ + NL C + ++ +++ I+ P + LC + S ++ +K+ F + GF SY +D G++ + ++ GY G+ N Y N +C++ + N+ I I F+ D +L HQD ++++ G R CG S P + + S + + F +N GF A Y F+D G I + G I SP+YP Y S C L A P+ I LTF+ F IE +C+ + + G P+S + G +S + S SN + V F +D + +G GF W
Sbjct: 2228 SAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIE-VTPNCTSNYLELRDGVDS------------DAPILSKFCGTSL---PSSQWSSGEVMYLRFRSD-------NSPTH---VGFKAKYSI---------------AQCGGRVPGQSGVVESIGHPTLP--YRDNLFCEWHLQGLSG-HYLTISFEDFNL-QNSSGCEKDFVEIWD----NHTSGNILGRYCGNTIPDSID--TSSNTAVVRFVT----------------DGSVTASGFRLRFESSME-----------------ECGGDLQG---SIGTFTSPNYPNPNPHGRICEWRITA------PEGRRITLMFNNLRLATHPSCNNEHVIVFN--------------GIRSNSPQLEKLCSS--VNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCGGSLPNTPEGNFT----SPGYDGVRN-------YSRNLNCEWT-LSNPNQGNSSISIHFE-------------DFYLESHQD--CQFDVLEFRVGDADGPLMWRLCGPSKPTLPLVIPYSQVW-IHFVTNERVEHIGFHAKYS-------FTDCGGIQIGDS---GVITSPNYPNAYDSLTHCSSLLEA--PQGHTITLTFSDFDIE-PHTTCAWDSVTVRNG--GSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGG-GFYATW 2798 HSP 11 Score: 67.0106 bits (162), Expect = 1.886e-10 Identity = 145/699 (20.74%), Postives = 254/699 (36.34%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGL--LPSTLNCIYEFRSESTL-ARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADN----RLCGI-KDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTV-AEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSK---SCSNAVLRIYEGFNV--KPQSELCGTDSAIP 2264
G SPN+P P + E ++ L F + + SC +++ ++ ++S + P L + C S + + I S N + + FF+D + + GF A+++ SS + C + + G +SP Y G+ LNC + + + + I + F DF L + + C + +E DAD RLCG K ++++++ V +++IGF K++F+D C IQ D G I SP A + C+ + L F+ ++ C +++ + +I +Y + P + G N L ++ S + + + GF ++ + G G S G I SP + +P NS C + ++ + I F + +P+ C ++ V A + + L T CG PG +++ + FT F+S GF AS F +CGSN + S GYI SP+YP +Y +++ C + + A +P +LTF SF +E S SC N + I G++V P + +CG + P
Sbjct: 2461 GTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRL-ATHPSCNNEHVIVFNGIRS------------NSPQLEKLC--SSVNVSNEIKSSGNTMKVIFFTDGSRPYG----------GFTASYT------------SSEDAVCGGSLP--NTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYL-ESHQDCQFDVLEF--------RVGDADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVT----------------NERVEHIGFHAKYSFTD-------------------CG-GIQIGD--SGVITSPNYPNAYDSLTHCSSLLEAPQG----HTITLTFSDFDIEPHT--TCAWDSVTVRNGGSPESPIIGQY---CGNSNPRTIQSGSNQLVVTFNSDHSL-------------QGGGFYATWN-TQTLGCGGIFHSD--------------NGTIRSPHWPQNFPENSRCSWTAITHKSKHLE---ISFDNNFLIPSG-------DGQCQNSFVKVWAGTEEVDKALLATG-----CGNVAPGPVITPSNT--FTAVFQSQ-EAPAQGFSAS---------FVSRCGSNFTGPS--GYIISPNYPKQYDNNMNCTYVIEA-NPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAP 3006 HSP 12 Score: 60.4622 bits (145), Expect = 1.944e-8 Identity = 53/193 (27.46%), Postives = 83/193 (43.01%), Query Frame = 3
Query: 1773 HLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
H +C DYL V + + L + CG P ++ S S+ L +++ + G GF A Y+ + V +Q YG + S YP YS + C W + A + TF +F +E +CS L +Y+G + CG D P +SS ++V LTD + +GFQ+ W
Sbjct: 1215 HPNCTLDYLAVYDGPSSNSHLLT-----QLCGDEKPPLIRSSGDSMFIKL--RTDEGQQGRGFKAEYRQTCENVVIVNQ---------TYGILESIGYPNPYSENQHCNWTIRATT-GNTVNYTFLAFDLE-HHINCSTDYLELYDG--PRQMGRYCGVDLPPPGSTTSSK-LQVLLLTDGVGRREKGFQMQW 1386 HSP 13 Score: 57.7658 bits (138), Expect = 1.378e-7 Identity = 60/246 (24.39%), Postives = 97/246 (39.43%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYEHFYSNKMTGG--ILLSPNWPGKYPQDVRYVYVFMGSEN-EQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEI 845
LFL F S N F + + +T + SP +P YP + ++ + L+F HF +E S +C +D+++I + P+ GR+CG + PH I S ++ + L F SD + + GF + S FY+ G +SP YP + P + C++ S S R++L FI F L + + C +FVEI
Sbjct: 1597 LFLRFQSGPSRQNRGFRAQFRQACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELE-RSTTCARDFVEI------------LDGGHEDAPLRGRYCGTDM---PHPITSFSSALTLRFVSDSS----------ISAGGFHTTVTASV----------SACGGTFYMAE------GIFNSPGYPDIYPPNVECVWNIVS-SPGNRLQLSFISFQL-EDSQDCSRDFVEI 1798 HSP 14 Score: 56.6102 bits (135), Expect = 2.683e-7 Identity = 43/146 (29.45%), Postives = 68/146 (46.58%), Query Frame = 3
Query: 129 FLSITKIANSSIEN-IFYEHFYSNKMTGGILL--------SPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQF 539
FL +T + +SS EN F F + + G +L SP P YP + + + N +HL FE F++E ++C DYL++Y + S E LGR+CG S IP ++ S N ++L F +D + +
Sbjct: 905 FLYVTFVKSSSTENHGFMAKFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLE-FHYNCTNDYLEVY-DTDS-------------ETSLGRYCGKS---IPPSLTSSGNSLMLVFVTDSDLAY 1032 HSP 15 Score: 53.5286 bits (127), Expect = 2.367e-6 Identity = 49/167 (29.34%), Postives = 75/167 (44.91%), Query Frame = 3
Query: 1857 RYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
R+CG+S+P L+S +L F L S +NG GF ++ + +CG + T YG I SP YPG Y C W + SP TF + +E C+ L I +G + + C T S +P ++ F R+ F +D + +GF I +
Sbjct: 547 RFCGSSLPHELLSSDNALYFHL--YSEHLRNGRGFTVRWETQQP------ECGGIL--TGPYGSIKSPGYPGNYPPGRDCVW-IVVTSPDLLVTFTFGTLSLE-HHDDCNKDYLEIRDGPLYQDPLLGKFCTTFS-VPPLQTTGPFARIHFHSD-SQISDQGFHITY 699
BLAST of Cubilin vs. Ensembl Human
Match: PCOLCE2 (procollagen C-endopeptidase enhancer 2 [Source:HGNC Symbol;Acc:HGNC:8739]) HSP 1 Score: 75.8702 bits (185), Expect = 1.023e-13 Identity = 70/262 (26.72%), Postives = 110/262 (41.98%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGR-YSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTD--ITSKGARGFQIVWTRVIP 2366
TG G I S + YP NS C + +++ L F D +L C D++ V NG + R+CGT PG LVS + + S+A+ G GF+A + + + CG + S G +P++P R Y + + C WH+ V+PK + I L F F +E C + ++ G V + CG DS S N + ++FL+D +T+ G G I + +P
Sbjct: 38 TGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESD-----------NL-CRYDFVDVY------NGHANGQRIGRFCGTFRPGALVSSGNKM--MVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPS--GSFKTPNWPDRDYPAGVTCVWHI--VAPKNQLIELKFEKFDVE-RDNYCRYDYVAVFNGGEVNDARRIGKYCG-DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLP 273 HSP 2 Score: 56.225 bits (134), Expect = 2.240e-7 Identity = 62/254 (24.41%), Postives = 105/254 (41.34%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFS-FKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGL-LPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLV 959
G + S +PG YP + + + E + V LNF ++E + C D++D+Y N + +GRFCG F P +VS N +++ SD NT + GF A FS + NE +Y C L+ +G +P +P P+ + C++ + I L F F++ ++D C ++V + N ++ NDA + CG S N L ++ +
Sbjct: 42 GFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNL-CRYDFVDVY-------------NGHANGQRIGRFCGT---FRPGALVSSGNKMMVQMISDANTAGN----------GFMAMFSAAEPNERGDQY--------CGGLLD---RPSGSFKTPNWPDRDYPAGVTCVWHIVAPKN-QLIELKFEKFDV-ERDNYCRYDYVAVFNGGEV----NDARRIGKYCGDSPPAPIVSERNELLIQFL 251
BLAST of Cubilin vs. Ensembl Human
Match: PCOLCE2 (procollagen C-endopeptidase enhancer 2 [Source:HGNC Symbol;Acc:HGNC:8739]) HSP 1 Score: 75.485 bits (184), Expect = 1.325e-13 Identity = 69/262 (26.34%), Postives = 108/262 (41.22%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGR-YSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTD--ITSKGARGFQIVWTRVIP 2366
TG G I S + YP NS C + +++ L F D C D++ V NG + R+CGT PG LVS + + S+A+ G GF+A + + + CG + S G +P++P R Y + + C WH+ V+PK + I L F F +E C + ++ G V + CG DS S N + ++FL+D +T+ G G I + +P
Sbjct: 38 TGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDN------------LCRYDFVDVY------NGHANGQRIGRFCGTFRPGALVSSGNKM--MVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPS--GSFKTPNWPDRDYPAGVTCVWHI--VAPKNQLIELKFEKFDVE-RDNYCRYDYVAVFNGGEVNDARRIGKYCG-DSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLP 273 HSP 2 Score: 56.225 bits (134), Expect = 2.133e-7 Identity = 65/259 (25.10%), Postives = 108/259 (41.70%), Query Frame = 3
Query: 201 MTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFS-FKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGL-LPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLV 959
+TG G + S +PG YP + + + E + V LNF ++E + C D++D+Y + N I GRFCG F P +VS N +++ SD NT + GF A FS + NE +Y C L+ +G +P +P P+ + C++ + I L F F++ ++D C ++V + N ++ NDA + CG S N L ++ +
Sbjct: 37 LTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNL-CRYDFVDVY---NGHANGQRI----------GRFCG---TFRPGALVSSGNKMMVQMISDANTAGN----------GFMAMFSAAEPNERGDQY--------CGGLLDRP---SGSFKTPNWPDRDYPAGVTCVWHIVAPKNQL-IELKFEKFDV-ERDNYCRYDYVAVFNGGEV----NDARRIGKYCGDSPPAPIVSERNELLIQFL 251
BLAST of Cubilin vs. Ensembl Human
Match: TLL1 (tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843]) HSP 1 Score: 76.2554 bits (186), Expect = 2.090e-13 Identity = 167/764 (21.86%), Postives = 280/764 (36.65%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYE------------PLNALYNRQDHI-PGTECDIKIQSSDQS--------EGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYS-VSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKD-------------FGISGTMVSRGRCHY-----RYQSEETGYRGLINSPF-------YTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYG--YIHSPHYPGRYSSDLICEWHLHAVSPK-ERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQI 2345
G L SP +P YP ++ + E++ LNF ++ S C D YIEV+ R P+LGRFCG D +P + S ++ + ++F S N + K +A+ + + C I N G+I SP YP C+++ + S + L F F + + D C +++E+ + S+++ R CG S+ N L+++ V ++ GF F F ++ E LN L + Q PG E +S + + G I +PG + K C + + TQ V+ F L E+ C+ Y+ I+S +S E K K + E Q N ++ + S N V ++GFK + KD G+ + + R + ++ +E I+SP + + YPS C ++ A I+L F F+ + H C D+L V + ++ L R CG IP LV+ + + F S+A GF A++ S +CG + + S Y H+ Y + CEW L VS + R L+F +F++E C + +++G + CG+ +S + + + F TD T +GF I
Sbjct: 358 GNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSL-CWYD----YIEVRDGYWR--------KSPLLGRFCG---DKLPEVLTSTDSRMWIEFRSSSN--------------------------WVGKGFAAVYEAICGGEIRKN---EGQIQSPNYPDDYRPMKECVWKI-TVSESYHVGLTFQSFEIERHDN-CAYDYLEVRDG---TSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVS----------------DGTVNKAGFAANF-FKEEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNC--VWQVVAPTQYRISVKFEFFELEGNEV----CKYDYVEIWSGLSSESKLHGKFCGAEVPEVITSQF----NNMRIEFKSDNTV-------------SKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQ------------HQECAYDHLEVFDGETEKSPILG-----RLCGNKIPDPLVATGNKM--FVRFVSDASVQRKGFQATH---------STECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLL--VSERGSRLELSFQTFEVE-EEADCGYDYVELFDGLDSTAVGLGRFCGSGPP-EEIYSIGDSVLIHFHTDDTIN-KKGFHI 998
BLAST of Cubilin vs. Ensembl Human
Match: TLL1 (tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843]) HSP 1 Score: 75.8702 bits (185), Expect = 2.749e-13 Identity = 67/280 (23.93%), Postives = 115/280 (41.07%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSH---------------------------HSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLA 968
G + +P WP +YP + V+ + ++ + FE F +EG C+ DY++I+ S + + G+FCG +P I S+ N N + + D+ + K GFKA+F +E H + C IH S +G I+SP +P PS C +E S + RI+L F +F + Q E C + +E+ + +++ + RLCG K ++ N++++R V A
Sbjct: 650 GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEV-CKYDYVEIW------------SGLSSESKLHGKFCGAE---VPEVITSQFN----------NMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIH---SPSGLITSPNWPDKYPSRKECTWEI-SATPGHRIKLAFSEFEIEQHQE-CAYDHLEVFDG---ETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDA 895 HSP 2 Score: 60.077 bits (144), Expect = 2.650e-9 Identity = 57/231 (24.68%), Postives = 98/231 (42.42%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG 902
G++ SPNWP KYP + + ++ L F F IE C D+L+++ + ++ K+ P+LGR CG+ IP +V+ N + + F SD + Q Q H + G + K ++ + HA + YPG ++C + SE +R+ L F F + +++ C ++VE+ + LDS + R CG
Sbjct: 806 GLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQ-ECAYDHLEVF-DGETEKS-----------PILGRLCGNK---IPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLKAESKPRDLYS---------------HA------QFGDNNYPG----QVDCEWLLVSERG-SRLELSFQTFEV-EEEADCGYDYVELFD--GLDSTAVGL-GRFCG 990 HSP 3 Score: 22.7126 bits (47), Expect = 2.650e-9 Identity = 8/12 (66.67%), Postives = 8/12 (66.67%), Query Frame = 2
Query: 68 NSFELHDNAHSC 103
N F LHDN H C
Sbjct: 781 NGFVLHDNKHDC 792 HSP 4 Score: 60.8474 bits (146), Expect = 1.227e-8 Identity = 63/249 (25.30%), Postives = 101/249 (40.56%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYG--YIHSPHYPGRYSSDLICEWHLHAVSPK-ERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQI 2345
GLI SP + + YPS C ++ A I+L F F+ + H C D+L V + ++ L R CG IP LV+ + + F S+A GF A++ S +CG + + S Y H+ Y + CEW L VS + R L+F +F++E C + +++G + CG+ +S + + + F TD T +GF I
Sbjct: 806 GLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQ------------HQECAYDHLEVFDGETEKSPILG-----RLCGNKIPDPLVATGNKM--FVRFVSDASVQRKGFQATH---------STECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLL--VSERGSRLELSFQTFEVE-EEADCGYDYVELFDGLDSTAVGLGRFCGSGPP-EEIYSIGDSVLIHFHTDDTIN-KKGFHI 1021 HSP 5 Score: 60.077 bits (144), Expect = 2.187e-8 Identity = 54/186 (29.03%), Postives = 78/186 (41.94%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLS--CHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIE 2165
G ++SP + N YPS + C + E I L F D++ S C DY+ V + R++ L R+CG +P +L S + + F+S+++ G GF A Y+ I CG I G I SP+YP Y C W + VS LTF SF+ E
Sbjct: 358 GNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTM--------------DLYKSSLCWYDYIEVRDGYWRKSPLLG-----RFCGDKLPEVLTSTDSRM--WIEFRSSSNWVGKGFAAVYEAI---------CGGEIRKNE--GQIQSPNYPDDYRPMKECVWKI-TVSESYHVGLTFQSFEQE 510
BLAST of Cubilin vs. Ensembl Celegans
Match: lev-10 (LEV-10B [Source:UniProtKB/TrEMBL;Acc:G5EER3]) HSP 1 Score: 258.84 bits (660), Expect = 1.642e-72 Identity = 233/872 (26.72%), Postives = 384/872 (44.04%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFY-EHFYSNKMTGGILLSPNWPGKY----------PQ---DVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASS--HHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQ---DHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNL-------------PEMKDFKCQDGYLSIYSVSFEMKYLIKRYR------TVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQ---QGFKLSYRFLKDFGISG-TMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKV-----------FSDQCGSNISSTSYY--GYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEG----TSKSCSNAVLRIYEGFNVKPQSELCGTDSA-IPSYFSSSNFIRVRFLTDITS-KGARGFQIVWTRV--IPRLSNGSCPG---FQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAE 2534
LFL+ + ++K +S + IF + + G++ P+ P + P+ +++ VY F+ ++V L F+HF + G S +C+ +Y+DIY EV+S + + + GR+CG PH +S V+ L S + + ++D+H GF+A +SF + K+ A C ++I ++ G + SPTYPG P ++C Y ++ RIRL F DF+++ E CP + V I + P + ++ ++CG++ + +S N L + H + + GF + + FS ++ ++ L N+Q HI GTECD++++S+ ++ I SP A C Y G+ QN+E V L F + + ++ D C ++ I MK ++ T+ + P+ L G Y S P ++++ T+ R + GFK + F DFG++G ++ + C +R+ S G NSP Y YP +++C Y + + I L F F S + DYL V ++ + NG + + ERYC + PG VS S + F S + GF A ++ RK + +CGS I+STS G I SP+YP +Y+ D+ C+W ++ V + +L + +EG SC AV+R+ G P+SE CGT +Y S SN +R+ FLT G +GF + WT V + C + C S CI L CN + NCG V D +DE Q C + E
Sbjct: 6 LFLLSIFVSKADGNSRKTIFQCDQHFDESQPEGVIEFPSLPKQLALSHGVNNSKPEQQYNLQCVYTFVAGSRQRVRLEFDHFLLSGSSENCDIEYVDIYSEVES------VDEDILSSALGGRYCG---TVAPHVRISLRRVMKLVLHS----RSTNHEDNH----GFRAKYSFIPED---KFIAGEPVGGKKCSFIIDSSDRKIGTLYSPTYPGTYPHNMHCSYLMKAGRG-ERIRLFFTDFDIFFGGEHCPYDSVTIFDGP---TPASPIIRKVCGLQQRMEVYSMGNSLLI--------------HFNTTHPAKSDPRGFIMDYEFSTRFVNIDKLLNKQRGVTHIRGTECDVRVESNRETFHTISSPNYPEVYPANTTCTYIIHGLQGEQNLEKVILTFDSIAVLSFDTSPATAPPSADIDDIACPSAWVGIAIGEGNMKAVMSSTDDSTFDVTLCERIPPNSPLLGP------YISEGPRMVMQFGSTE-TRDDNISPIGFKATIEFKTDFGVTGESLGTSNECKFRFTSST----GFFNSPRYPANYPLDTNCTYYIVGQPGKEILLHFEQFALSGNTDNNC-----------NDYLDVYDVFVK-NGKEELRRKERYCADTFPGPSVSAFGSHEMRVVFTSGSSGTANGFKALFEIRTARKEDVPRGEAHIRRGAYRCGSVINSTSEKPNGLIISPNYPVKYNKDVHCDWQIN-VKEGYQVLLKMEAIDVEGEMTSNGASCQKAVIRVDGG----PRSEYCGTKREFFEAYLSPSNSVRISFLTAPDKVNGLKGFNLSWTEVKNLSGKDENVCKSDSLYLCTYSKLCIDAKLRCNGLDNCGYGVQ-------DDTDE-QHCSLKE 803
BLAST of Cubilin vs. Ensembl Celegans
Match: lev-10 (LEV-10B [Source:UniProtKB/TrEMBL;Acc:G5EER3]) HSP 1 Score: 257.299 bits (656), Expect = 1.664e-72 Identity = 227/853 (26.61%), Postives = 376/853 (44.08%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFY-EHFYSNKMTGGILLSPNWPGKY----------PQ---DVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASS--HHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQ---DHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNL-------------PEMKDFKCQDGYLSIYSVSFEMKYLIKRYR------TVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQ---QGFKLSYRFLKDFGISG-TMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKV-----------FSDQCGSNISSTSYY--GYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEG----TSKSCSNAVLRIYEGFNVKPQSELCGTDSA-IPSYFSSSNFIRVRFLTDITS-KGARGFQIVWTRV--IPRLSNGSCPG---FQCLNSGHCISKNLTCNKVFNCGSYVNN 2477
LFL+ + ++K +S + IF + + G++ P+ P + P+ +++ VY F+ ++V L F+HF + G S +C+ +Y+DIY EV+S + + + GR+CG PH +S V+ L S + + ++D+H GF+A +SF + K+ A C ++I ++ G + SPTYPG P ++C Y ++ RIRL F DF+++ E CP + V I + P + ++ ++CG++ + +S N L + H + + GF + + FS ++ ++ L N+Q HI GTECD++++S+ ++ I SP A C Y G+ QN+E V L F + + ++ D C ++ I MK ++ T+ + P+ L G Y S P ++++ T+ R + GFK + F DFG++G ++ + C +R+ S G NSP Y YP +++C Y + + I L F F S + Y DV+ V +NG + + ERYC + PG VS S + F S + GF A ++ RK + +CGS I+STS G I SP+YP +Y+ D+ C+W ++ V + +L + +EG SC AV+R+ G P+SE CGT +Y S SN +R+ FLT G +GF + WT V + C + C S CI L CN + NCG V +
Sbjct: 6 LFLLSIFVSKADGNSRKTIFQCDQHFDESQPEGVIEFPSLPKQLALSHGVNNSKPEQQYNLQCVYTFVAGSRQRVRLEFDHFLLSGSSENCDIEYVDIYSEVES------VDEDILSSALGGRYCG---TVAPHVRISLRRVMKLVLHS----RSTNHEDNH----GFRAKYSFIPED---KFIAGEPVGGKKCSFIIDSSDRKIGTLYSPTYPGTYPHNMHCSYLMKAGRG-ERIRLFFTDFDIFFGGEHCPYDSVTIFDGP---TPASPIIRKVCGLQQRMEVYSMGNSLLI--------------HFNTTHPAKSDPRGFIMDYEFSTRFVNIDKLLNKQRGVTHIRGTECDVRVESNRETFHTISSPNYPEVYPANTTCTYIIHGLQGEQNLEKVILTFDSIAVLSFDTSPATAPPSADIDDIACPSAWVGIAIGEGNMKAVMSSTDDSTFDVTLCERIPPNSPLLGP------YISEGPRMVMQFGSTE-TRDDNISPIGFKATIEFKTDFGVTGESLGTSNECKFRFTSST----GFFNSPRYPANYPLDTNCTYYIVGQPGKEILLHFEQFALSGNTDNNCNDYLDVY------------DVFVKNGKEELRRKERYCADTFPGPSVSAFGSHEMRVVFTSGSSGTANGFKALFEIRTARKEDVPRGEAHIRRGAYRCGSVINSTSEKPNGLIISPNYPVKYNKDVHCDWQIN-VKEGYQVLLKMEAIDVEGEMTSNGASCQKAVIRVDGG----PRSEYCGTKREFFEAYLSPSNSVRISFLTAPDKVNGLKGFNLSWTEVKNLSGKDENVCKSDSLYLCTYSKLCIDAKLRCNGLDNCGYGVQD 792
BLAST of Cubilin vs. Ensembl Celegans
Match: lev-10 (LEV-10B [Source:UniProtKB/TrEMBL;Acc:G5EER3]) HSP 1 Score: 121.324 bits (303), Expect = 2.420e-29 Identity = 97/371 (26.15%), Postives = 176/371 (47.44%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFY-EHFYSNKMTGGILLSPNWPGKY----------PQ---DVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASS--HHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQ---DHIPGTECDIKIQSSDQSEGYIISP 1172
LFL+ + ++K +S + IF + + G++ P+ P + P+ +++ VY F+ ++V L F+HF + G S +C+ +Y+DIY EV+S + + + GR+CG PH +S V+ L S ++D+H GF+A +SF + K+ A C ++I ++ G + SPTYPG P ++C Y ++ RIRL F DF+++ E CP + V I + P + ++ ++CG++ + +S N L + H + + GF + + FS ++ ++ L N+Q HI GTECD++++S+ ++ I SP
Sbjct: 6 LFLLSIFVSKADGNSRKTIFQCDQHFDESQPEGVIEFPSLPKQLALSHGVNNSKPEQQYNLQCVYTFVAGSRQRVRLEFDHFLLSGSSENCDIEYVDIYSEVES------VDEDILSSALGGRYCG---TVAPHVRISLRRVMKLVLHSRSTN----HEDNH----GFRAKYSFIPED---KFIAGEPVGGKKCSFIIDSSDRKIGTLYSPTYPGTYPHNMHCSYLMKAGRG-ERIRLFFTDFDIFFGGEHCPYDSVTIFDGP---TPASPIIRKVCGLQQRMEVYSMGNSLLI--------------HFNTTHPAKSDPRGFIMDYEFSTRFVNIDKLLNKQRGVTHIRGTECDVRVESNRETFHTISSP 338 HSP 2 Score: 72.0182 bits (175), Expect = 4.860e-13 Identity = 69/240 (28.75%), Postives = 103/240 (42.92%), Query Frame = 3
Query: 1656 NSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRK------VFSDQCGSNI-SSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQS----ELCGTDSAIPSYFSSSNFIRVRFLTDITSKG-ARGF 2339
N C Y F A S + +RL F F S Y D++ +E+ + L + RYCGT P + +S ++ + L +S H++ GF A Y FI + K V +C I SS G ++SP YPG Y ++ C + + A ER L FT F I + C + I++G P S ++CG + Y S N + + F T +K RGF
Sbjct: 65 NLQCVYTFVAGSRQRVRLEFDHFLLSGSSENCDIEYVDIY----------SEVESVDEDILSSALGGRYCGTVAPHVRISLRRVMKLVLHSRSTNHEDNHGFRAKYSFIPEDKFIAGEPVGGKKCSFIIDSSDRKIGTLYSPTYPGTYPHNMHCSYLMKA-GRGERIRLFFTDFDIFFGGEHCPYDSVTIFDG--PTPASPIIRKVCGLQQRMEVY-SMGNSLLIHFNTTHPAKSDPRGF 290
BLAST of Cubilin vs. Ensembl Celegans
Match: sol-2 (SOL-2 protein; Suppressor Of Lurcher movement defect [Source:UniProtKB/TrEMBL;Acc:Q9XUU2]) HSP 1 Score: 86.6557 bits (213), Expect = 1.650e-17 Identity = 86/362 (23.76%), Postives = 143/362 (39.50%), Query Frame = 3
Query: 1554 TMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQK--SLGFTLTFKSNAHKNGPGFLASYQFIKKRKV-----------FSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF-------------NVKPQSELCGT-----DSAIPSYFSSSNFIRVRFLTD------ITSKGARGFQIVWTRVIPRLSNGS-------------CPGFQ-CLNSGH---------CISKNLTCNKVFNC 2459
T+++ C ++ T G I SP Y + + + C ++ ++ +I+L F+ F L S + + C YL V +V R + + ER CG +P + + Q + F T + H+ GF Y+ + + + FS CG + + G I SP YP Y + C W L V ++R + + T C A L I +G+ + +++ CG+ + + SY SS+N I VRF+T + + GF++VWT V + G C G Q C+ GH CI +L C+ + NC
Sbjct: 14 TLITCSYCPIKHIHSSTPTTGFIESPGYPSAFSAPLDCIFNITTAASNVIQLSFVSFD--------LASKNQLSDQCLDSYLLVV-VVDRHG---RQHVGERLCGNQVPLSINTMQSWMQVQFVTTSTNQKHR---GFRIQYRILSEAAIQEPSSTLGESMFSG-CGGHSTPGQLSGEILSPGYPTTYPKNSTCNW-LIRVEARQRIYIRIVHLHLAPTIAECERASLTIIDGYKHEKYGIDRKESTSETSEAKFCGSQLYYAEEGMKSYLSSANRIVVRFITQEGPPSSMIGEERIGFKVVWTAVEGLIGEGDESVNGNSCKDQFMCHGGQVCVEQGHGICASRSRLCIHSSLVCDGIHNC 358
BLAST of Cubilin vs. Ensembl Celegans
Match: nas-39 (Zinc metalloproteinase nas-39 [Source:UniProtKB/Swiss-Prot;Acc:Q20176]) HSP 1 Score: 80.8777 bits (198), Expect = 3.438e-15 Identity = 153/719 (21.28%), Postives = 255/719 (35.47%), Query Frame = 3
Query: 408 SNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDS--DSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQD--------HIPGTECDIKIQSSDQSEGY----------------IISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDF--------GISGTMVSR-----------------------GRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYI--HSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ---SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSN 2378
+N FH +L R CG D + I S N +++ S A+ F +++++ C I+AN G I SP YP P +C + + +++ ++F+ F+L Q E C + + + +S D + CG+ + S N++ LR +S+Q GF+++FT + LN ++ + G +C ++ S S G+ I SP K C + + LNFT N+ MK +C Y+ I + LCG+ + +T+ P +++ F+ E+ GF + F+ DF G T +R G C + E G INSP Y N YP +C + F + L F FQ E H C D ++V + G +CG + P +L+S L LTF S+A + GF A Y + CG +++ S G+I H+ +Y + C W + A SP + F++F IE + + C + IY+G + CG S P +S+ + + ++ +GF + R PR S+
Sbjct: 331 TNSFFHFEILDRICGG--DSLFRTIASSGNRMLIQVRSSTPA----------------ASLPF-----------ATYYAICGGPIYAN---EGVIHSPKYPESYPPNSDCQWTIHVDEN-SQVAIEFVYFHLEQHKE-CIYDRLILTEGISKNSKKDGKEMSETFCGLIEKKTIVSKTNQISLRF----------------FSDNSVQKTGFELRFT-----KELNECATDKNICHHYCVNTVGGFKCACRVGYSLSSNGFSCDSTCGGYLKASNGSISSPNFPEMYPNSKTCIWEIEAPDGYH----IFLNFTKFNVEGMKT-ECAYDYVKI---------------------GDSEKLCGEYHEALLFTT--PRNRVRIEFSSDSSVERDGFFAN--FIADFDECQNDNAGCEHTCQNRLGSYVCTCNPGYILAEDKHNCKEGSCFF----EVNAPAGDINSPNYPNDYPKGQNCSWHFVTTPGHRLMLTFSSFQVEE------------HAQCKYDAVSV-----YDGGDGSAQLAGVFCGLAPPPLLLSSSNEL--YLTFSSDASVSRRGFQAHYTSL---------CGGRLTAESTPGHIYSHATFSDSKYGKNQDCSWIVRAKSPGRGVRIQFSTFNIE-SEEGCQYDYIEIYDGPEATLERLVGRFCGDTS--PEVITSTGPELLLIMHTDNAEEEKGF-VAEYREAPRSSS 928 HSP 2 Score: 64.6994 bits (156), Expect = 3.481e-10 Identity = 84/321 (26.17%), Postives = 130/321 (40.50%), Query Frame = 3
Query: 12 FYF*IAGGLCSENENFQFLIHL-NYMIMLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIY--IEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITK----------------------YWASSHHSSC-----FYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDA 884
F+F I +C + F+ + N M++ + + L F + I I Y+N+ G++ SP +P YP + + EN QV + F +F++E C D L + I S K+ +S FCG IVSK N I L FFSD + Q K GF+ F+ + NE T Y SS+ SC YL +NGS ISSP +P + P++ CI+E + I L+F FN+ C ++V+I + +L + ++A
Sbjct: 335 FHFEILDRICGGDSLFRTIASSGNRMLIQVRSSTPAASLPFATYYAICGGPI--------YANE---GVIHSPKYPESYPPNSDCQWTIHVDENSQVAIEFVYFHLEQHK-ECIYDRLILTEGISKNSKKDGKEMSET---------FCGL---IEKKTIVSKTNQISLRFFSDNSVQ----------KTGFELRFTKELNECATDKNICHHYCVNTVGGFKCACRVGYSLSSNGFSCDSTCGGYLKASNGS----ISSPNFPEMYPNSKTCIWEIEAPDGY-HIFLNFTKFNVEGMKTECAYDYVKIGDSEKLCGEYHEA 616
BLAST of Cubilin vs. Ensembl Fly
Match: CG42613 (gene:FBgn0261262 transcript:FBtr0304687) HSP 1 Score: 301.212 bits (770), Expect = 1.372e-86 Identity = 229/774 (29.59%), Postives = 359/774 (46.38%), Query Frame = 3
Query: 264 VYVFMGSENEQVHLNFEHFNIEGLSF---------SCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY--TGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALY-NRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMK-----DFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHY------PGRYSSDLICEWHLHAVSPKERFILTFTSFQIEG--TSKSCSNAVLRIYEGFNV-KPQSELCGTDSAIPS--YFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG-------------FQCLNSGHCISKNLTCNKVFNCG 2462
+Y F+ ++V + F+ FN+ G SC +Y+DIY EV+S + L + P GR+CG P +S + + FFS+KN F+ F F N + S C Y I + S TG + SPTYPG P ++C Y+F ES R+RL+F DF+L+ CP ++V++ + P +S+ CG + N +SS + L++ L+ ++ QN GFK + FS+ + L+ + N HI G+ECD KI S +S G+++SP + +C YF G+ + Q++E V+L F N+P+++ + C DGYL IY +K T K D LCG + S P + + + + + +GFK Y F ++ I GT G C + Y S + RG +NSP Y + YPS+++C Y F A+++E + ++F F+ D A T+ +C +D+L + + + N L RYCG + PG + S + ++G +T ++ GF A Y F + K + CG N S+ G I SP++ PGR + C W + A P + + F F +EG ++ C AVLR++ + +P ELCG + Y S+ R+ F T + GA+GF+IVWT + S PG FQC +G+CIS L C+ V NCG
Sbjct: 270 LYTFLAGPGQRVEVVFKSFNLRGSPPDGSAVGELPSCVHEYMDIYSEVQSSE-----PAELINSPFGGRYCG---TIPPRRRISMYRAVAISFFSNKNVTTDL----------FEGTFRF-INASEYEIGIPIAGSPCSYTITPSMSVNKTGALISPTYPGAYPKDMSCTYQFLGESN-QRVRLEFRDFDLFFGGPHCPFDYVKVYDGPD---NSSALIGTYCGQQRNLVLYSSESSLFVHFYTLS-------------RTANTQNRGFKGIYEFSESFVKLDFIRENDGIHIRGSECDQKILSKKESTGFVLSPNYPYPYIPKTVCRYFIYGMQDAQHLERVRLEFNAFNIPKVEHKDKSESNCTDGYLKIY---------LKGQETADAYDKFDYELCGNETQR--VISEGPRLAMVFSSGE---LQGRGFKGKYTFETEYKIPGTAAPDGTCSFTYVS-SSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRDNNDRL----LGRYCGQTAPGPVESPRGAVGLRITLHTDQESVASGFKARY-FFESAKSDAGDCGGNFSNQD-SGLITSPNWPAGYKAPGRGMASNACNWVMKA-RPGYKLSIHFEQFGLEGDPANRGCPAAVLRLWMNVDSDQPPLELCGEKPPVEQWHYTSTGQTARISFTTSDKTVGAQGFRIVWTEI-----QDSGPGPPSVGLHCESTYHFQC-GAGYCISDKLRCDGVKNCG 979 HSP 2 Score: 80.4925 bits (197), Expect = 5.877e-15 Identity = 92/365 (25.21%), Postives = 148/365 (40.55%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASS-----HHSSCFYLIHANGSYTGEISSPTYP-GLLPSTLNC---IYEFRSESTLARIRLDFIDFNLY------QQDEMCPVEFVEIINQPQLDSDSNDA-DNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTE-----CDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQ 1241
G L+SP +PG YP+D+ Y F+G N++V L F F++ C DY VK Y N S + +G +CG + + + S + + + F++ T + N+ GFK + F + + + + S C I + TG + SP YP +P T+ C IY + L R+RL+F FN+ + + C +++I + Q +D+ D D LCG + R++ R M+ LQ GFK K+TF +Y+ IPGT C SS + G + SP + C+Y F+ + Q
Sbjct: 402 GALISPTYPGAYPKDMSCTYQFLGESNQRVRLEFRDFDLFFGGPHCPFDY------VKVYDGPDNSSAL------IGTYCGQQRNLV---LYSSESSLFVHFYTLSRTANTQNR-------GFKGIYEFSESFVKLDFIRENDGIHIRGSECDQKILSKKESTGFVLSPNYPYPYIPKTV-CRYFIYGMQDAQHLERVRLEFNAFNIPKVEHKDKSESNCTDGYLKIYLKGQETADAYDKFDYELCGNETQ------------RVISEGPRLAMV------FSSGELQGRGFKGKYTFETEYK-----------IPGTAAPDGTCSFTYVSSSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQ 714 HSP 3 Score: 58.151 bits (139), Expect = 3.891e-8 Identity = 62/266 (23.31%), Postives = 106/266 (39.85%), Query Frame = 3
Query: 186 FYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEG-----------LSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY----TGEISSPTYP--------GLLPSTLNCIYEFRSESTLARIRLDFIDFNLY--QQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIK 908
+ S+ G L SP +P YP D Y+F+ +EQV + F+HF I+ S +C +D+L++Y+ + +R+ LGR+CG + P + S + L + + + D GFKA + F+ A S C G++ +G I+SP +P G+ + N + + R L+ + F F L + CP + + ++ DS+ LCG K
Sbjct: 678 YVSSSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRDNNDRL-----------LGRYCGQT---APGPVESPRGAVGL--------RITLHTDQESVASGFKARYFFES--------AKSDAGDC------GGNFSNQDSGLITSPNWPAGYKAPGRGMASNACNWVMKARPGYKLS---IHFEQFGLEGDPANRGCPAAVLRLW----MNVDSDQPPLELCGEK 900
BLAST of Cubilin vs. Ensembl Fly
Match: CG42613 (gene:FBgn0261262 transcript:FBtr0304688) HSP 1 Score: 301.597 bits (771), Expect = 4.220e-86 Identity = 229/774 (29.59%), Postives = 359/774 (46.38%), Query Frame = 3
Query: 264 VYVFMGSENEQVHLNFEHFNIEGLSF---------SCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY--TGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALY-NRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMK-----DFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHY------PGRYSSDLICEWHLHAVSPKERFILTFTSFQIEG--TSKSCSNAVLRIYEGFNV-KPQSELCGTDSAIPS--YFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG-------------FQCLNSGHCISKNLTCNKVFNCG 2462
+Y F+ ++V + F+ FN+ G SC +Y+DIY EV+S + L + P GR+CG P +S + + FFS+KN F+ F F N + S C Y I + S TG + SPTYPG P ++C Y+F ES R+RL+F DF+L+ CP ++V++ + P +S+ CG + N +SS + L++ L+ ++ QN GFK + FS+ + L+ + N HI G+ECD KI S +S G+++SP + +C YF G+ + Q++E V+L F N+P+++ + C DGYL IY +K T K D LCG + S P + + + + + +GFK Y F ++ I GT G C + Y S + RG +NSP Y + YPS+++C Y F A+++E + ++F F+ D A T+ +C +D+L + + + N L RYCG + PG + S + ++G +T ++ GF A Y F + K + CG N S+ G I SP++ PGR + C W + A P + + F F +EG ++ C AVLR++ + +P ELCG + Y S+ R+ F T + GA+GF+IVWT + S PG FQC +G+CIS L C+ V NCG
Sbjct: 270 LYTFLAGPGQRVEVVFKSFNLRGSPPDGSAVGELPSCVHEYMDIYSEVQSSE-----PAELINSPFGGRYCG---TIPPRRRISMYRAVAISFFSNKNVTTDL----------FEGTFRF-INASEYEIGIPIAGSPCSYTITPSMSVNKTGALISPTYPGAYPKDMSCTYQFLGESN-QRVRLEFRDFDLFFGGPHCPFDYVKVYDGPD---NSSALIGTYCGQQRNLVLYSSESSLFVHFYTLS-------------RTANTQNRGFKGIYEFSESFVKLDFIRENDGIHIRGSECDQKILSKKESTGFVLSPNYPYPYIPKTVCRYFIYGMQDAQHLERVRLEFNAFNIPKVEHKDKSESNCTDGYLKIY---------LKGQETADAYDKFDYELCGNETQR--VISEGPRLAMVFSSGE---LQGRGFKGKYTFETEYKIPGTAAPDGTCSFTYVS-SSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRDNNDRL----LGRYCGQTAPGPVESPRGAVGLRITLHTDQESVASGFKARY-FFESAKSDAGDCGGNFSNQD-SGLITSPNWPAGYKAPGRGMASNACNWVMKA-RPGYKLSIHFEQFGLEGDPANRGCPAAVLRLWMNVDSDQPPLELCGEKPPVEQWHYTSTGQTARISFTTSDKTVGAQGFRIVWTEI-----QDSGPGPPSVGLHCESTYHFQC-GAGYCISDKLRCDGVKNCG 979 HSP 2 Score: 80.4925 bits (197), Expect = 6.284e-15 Identity = 117/504 (23.21%), Postives = 194/504 (38.49%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASS-----HHSSCFYLIHANGSYTGEISSPTYP-GLLPSTLNC---IYEFRSESTLARIRLDFIDFNLY------QQDEMCPVEFVEIINQPQLDSDSNDA-DNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTE-----CDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVL---CGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFY 1649
G L+SP +PG YP+D+ Y F+G N++V L F F++ C DY VK Y N S + +G +CG + + + S + + + F++ T + N+ GFK + F + + + + S C I + TG + SP YP +P T+ C IY + L R+RL+F FN+ + + C +++I + Q +D+ D D LCG + R++ R M+ LQ GFK K+TF +Y+ IPGT C SS + G + SP + C+Y F+ + Q V + F + + + G Y + ++ Y V+ D++L CG+ + R + L++ GFK Y F G C + ++++ GLI SP + Y
Sbjct: 402 GALISPTYPGAYPKDMSCTYQFLGESNQRVRLEFRDFDLFFGGPHCPFDY------VKVYDGPDNSSAL------IGTYCGQQRNLV---LYSSESSLFVHFYTLSRTANTQNR-------GFKGIYEFSESFVKLDFIRENDGIHIRGSECDQKILSKKESTGFVLSPNYPYPYIPKTV-CRYFIYGMQDAQHLERVRLEFNAFNIPKVEHKDKSESNCTDGYLKIYLKGQETADAYDKFDYELCGNETQ------------RVISEGPRLAMV------FSSGELQGRGFKGKYTFETEYK-----------IPGTAAPDGTCSFTYVSSSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQ----VTIVFDHFKIKADNNANATAG---AYGSGACFEDWLEMY--VVYRDNNDRLLGRYCGQTAPGPVESPRG-AVGLRITLHTDQESVASGFKARYFF------ESAKSDAGDCGGNFSNQDS---GLITSPNWPAGY 834 HSP 3 Score: 57.7658 bits (138), Expect = 5.103e-8 Identity = 62/266 (23.31%), Postives = 106/266 (39.85%), Query Frame = 3
Query: 186 FYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEG-----------LSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY----TGEISSPTYP--------GLLPSTLNCIYEFRSESTLARIRLDFIDFNLY--QQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIK 908
+ S+ G L SP +P YP D Y+F+ +EQV + F+HF I+ S +C +D+L++Y+ + +R+ LGR+CG + P + S + L + + + D GFKA + F+ A S C G++ +G I+SP +P G+ + N + + R L+ + F F L + CP + + ++ DS+ LCG K
Sbjct: 678 YVSSSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRDNNDRL-----------LGRYCGQT---APGPVESPRGAVGL--------RITLHTDQESVASGFKARYFFES--------AKSDAGDC------GGNFSNQDSGLITSPNWPAGYKAPGRGMASNACNWVMKARPGYKLS---IHFEQFGLEGDPANRGCPAAVLRLW----MNVDSDQPPLELCGEK 900
BLAST of Cubilin vs. Ensembl Fly
Match: CG42613 (gene:FBgn0261262 transcript:FBtr0304685) HSP 1 Score: 301.597 bits (771), Expect = 4.818e-86 Identity = 229/774 (29.59%), Postives = 359/774 (46.38%), Query Frame = 3
Query: 264 VYVFMGSENEQVHLNFEHFNIEGLSF---------SCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY--TGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALY-NRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMK-----DFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHY------PGRYSSDLICEWHLHAVSPKERFILTFTSFQIEG--TSKSCSNAVLRIYEGFNV-KPQSELCGTDSAIPS--YFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG-------------FQCLNSGHCISKNLTCNKVFNCG 2462
+Y F+ ++V + F+ FN+ G SC +Y+DIY EV+S + L + P GR+CG P +S + + FFS+KN F+ F F N + S C Y I + S TG + SPTYPG P ++C Y+F ES R+RL+F DF+L+ CP ++V++ + P +S+ CG + N +SS + L++ L+ ++ QN GFK + FS+ + L+ + N HI G+ECD KI S +S G+++SP + +C YF G+ + Q++E V+L F N+P+++ + C DGYL IY +K T K D LCG + S P + + + + + +GFK Y F ++ I GT G C + Y S + RG +NSP Y + YPS+++C Y F A+++E + ++F F+ D A T+ +C +D+L + + + N L RYCG + PG + S + ++G +T ++ GF A Y F + K + CG N S+ G I SP++ PGR + C W + A P + + F F +EG ++ C AVLR++ + +P ELCG + Y S+ R+ F T + GA+GF+IVWT + S PG FQC +G+CIS L C+ V NCG
Sbjct: 303 LYTFLAGPGQRVEVVFKSFNLRGSPPDGSAVGELPSCVHEYMDIYSEVQSSE-----PAELINSPFGGRYCG---TIPPRRRISMYRAVAISFFSNKNVTTDL----------FEGTFRF-INASEYEIGIPIAGSPCSYTITPSMSVNKTGALISPTYPGAYPKDMSCTYQFLGESN-QRVRLEFRDFDLFFGGPHCPFDYVKVYDGPD---NSSALIGTYCGQQRNLVLYSSESSLFVHFYTLS-------------RTANTQNRGFKGIYEFSESFVKLDFIRENDGIHIRGSECDQKILSKKESTGFVLSPNYPYPYIPKTVCRYFIYGMQDAQHLERVRLEFNAFNIPKVEHKDKSESNCTDGYLKIY---------LKGQETADAYDKFDYELCGNETQR--VISEGPRLAMVFSSGE---LQGRGFKGKYTFETEYKIPGTAAPDGTCSFTYVS-SSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRDNNDRL----LGRYCGQTAPGPVESPRGAVGLRITLHTDQESVASGFKARY-FFESAKSDAGDCGGNFSNQD-SGLITSPNWPAGYKAPGRGMASNACNWVMKA-RPGYKLSIHFEQFGLEGDPANRGCPAAVLRLWMNVDSDQPPLELCGEKPPVEQWHYTSTGQTARISFTTSDKTVGAQGFRIVWTEI-----QDSGPGPPSVGLHCESTYHFQC-GAGYCISDKLRCDGVKNCG 1012 HSP 2 Score: 80.4925 bits (197), Expect = 5.988e-15 Identity = 119/504 (23.61%), Postives = 196/504 (38.89%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASS-----HHSSCFYLIHANGSYTGEISSPTYP-GLLPSTLNC---IYEFRSESTLARIRLDFIDFNLY------QQDEMCPVEFVEIINQPQLDSDSNDA-DNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTE-----CDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVL---CGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFY 1649
G L+SP +PG YP+D+ Y F+G N++V L F F++ C DY VK Y N S + +G +CG + + + S + + + F++ T + N+ GFK + F + + + + S C I + TG + SP YP +P T+ C IY + L R+RL+F FN+ + + C +++I + Q +D+ D D LCG + + S R L +V +G LQ GFK K+TF +Y+ IPGT C SS + G + SP + C+Y F+ + Q V + F + + + G Y + ++ Y V+ D++L CG+ + R + L++ GFK Y F G C + ++++ GLI SP + Y
Sbjct: 435 GALISPTYPGAYPKDMSCTYQFLGESNQRVRLEFRDFDLFFGGPHCPFDY------VKVYDGPDNSSAL------IGTYCGQQRNLV---LYSSESSLFVHFYTLSRTANTQNR-------GFKGIYEFSESFVKLDFIRENDGIHIRGSECDQKILSKKESTGFVLSPNYPYPYIPKTV-CRYFIYGMQDAQHLERVRLEFNAFNIPKVEHKDKSESNCTDGYLKIYLKGQETADAYDKFDYELCG-NETQRVISEGPR--LAMVFSSGE---------------LQGRGFKGKYTFETEYK-----------IPGTAAPDGTCSFTYVSSSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQ----VTIVFDHFKIKADNNANATAG---AYGSGACFEDWLEMY--VVYRDNNDRLLGRYCGQTAPGPVESPRG-AVGLRITLHTDQESVASGFKARYFF------ESAKSDAGDCGGNFSNQDS---GLITSPNWPAGY 867 HSP 3 Score: 58.151 bits (139), Expect = 4.563e-8 Identity = 62/266 (23.31%), Postives = 106/266 (39.85%), Query Frame = 3
Query: 186 FYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEG-----------LSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY----TGEISSPTYP--------GLLPSTLNCIYEFRSESTLARIRLDFIDFNLY--QQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIK 908
+ S+ G L SP +P YP D Y+F+ +EQV + F+HF I+ S +C +D+L++Y+ + +R+ LGR+CG + P + S + L + + + D GFKA + F+ A S C G++ +G I+SP +P G+ + N + + R L+ + F F L + CP + + ++ DS+ LCG K
Sbjct: 711 YVSSSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRDNNDRL-----------LGRYCGQT---APGPVESPRGAVGL--------RITLHTDQESVASGFKARYFFES--------AKSDAGDC------GGNFSNQDSGLITSPNWPAGYKAPGRGMASNACNWVMKARPGYKLS---IHFEQFGLEGDPANRGCPAAVLRLW----MNVDSDQPPLELCGEK 933
BLAST of Cubilin vs. Ensembl Fly
Match: CG42613 (gene:FBgn0261262 transcript:FBtr0304686) HSP 1 Score: 286.574 bits (732), Expect = 1.077e-82 Identity = 219/733 (29.88%), Postives = 341/733 (46.52%), Query Frame = 3
Query: 360 LDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY--TGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALY-NRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMK-----DFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHY------PGRYSSDLICEWHLHAVSPKERFILTFTSFQIEG--TSKSCSNAVLRIYEGFNV-KPQSELCGTDSAIPS--YFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG-------------FQCLNSGHCISKNLTCNKVFNCG 2462
+DIY EV+S + L + P GR+CG P +S + + FFS+KN F+ F F N + S C Y I + S TG + SPTYPG P ++C Y+F ES R+RL+F DF+L+ CP ++V++ + P +S+ CG + N +SS + L++ L+ ++ QN GFK + FS+ + L+ + N HI G+ECD KI S +S G+++SP + +C YF G+ + Q++E V+L F N+P+++ + C DGYL IY +K T K D LCG + S P + + + + + +GFK Y F ++ I GT G C + Y S + RG +NSP Y + YPS+++C Y F A+++E + ++F F+ D A T+ +C +D+L + + + N L RYCG + PG + S + ++G +T ++ GF A Y F + K + CG N S+ G I SP++ PGR + C W + A P + + F F +EG ++ C AVLR++ + +P ELCG + Y S+ R+ F T + GA+GF+IVWT + S PG FQC +G+CIS L C+ V NCG
Sbjct: 1 MDIYSEVQSSE-----PAELINSPFGGRYCG---TIPPRRRISMYRAVAISFFSNKNVTTDL----------FEGTFRF-INASEYEIGIPIAGSPCSYTITPSMSVNKTGALISPTYPGAYPKDMSCTYQFLGESN-QRVRLEFRDFDLFFGGPHCPFDYVKVYDGPD---NSSALIGTYCGQQRNLVLYSSESSLFVHFYTLS-------------RTANTQNRGFKGIYEFSESFVKLDFIRENDGIHIRGSECDQKILSKKESTGFVLSPNYPYPYIPKTVCRYFIYGMQDAQHLERVRLEFNAFNIPKVEHKDKSESNCTDGYLKIY---------LKGQETADAYDKFDYELCGNETQR--VISEGPRLAMVFSSGE---LQGRGFKGKYTFETEYKIPGTAAPDGTCSFTYVS-SSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRDNNDRL----LGRYCGQTAPGPVESPRGAVGLRITLHTDQESVASGFKARY-FFESAKSDAGDCGGNFSNQD-SGLITSPNWPAGYKAPGRGMASNACNWVMKA-RPGYKLSIHFEQFGLEGDPANRGCPAAVLRLWMNVDSDQPPLELCGEKPPVEQWHYTSTGQTARISFTTSDKTVGAQGFRIVWTEI-----QDSGPGPPSVGLHCESTYHFQC-GAGYCISDKLRCDGVKNCG 669 HSP 2 Score: 80.4925 bits (197), Expect = 5.117e-15 Identity = 127/547 (23.22%), Postives = 209/547 (38.21%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASS-----HHSSCFYLIHANGSYTGEISSPTYP-GLLPSTLNC---IYEFRSESTLARIRLDFIDFNLY------QQDEMCPVEFVEIINQPQLDSDSNDA-DNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTE-----CDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQ------NMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFE-MKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYP------SNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPA 1748
G L+SP +PG YP+D+ Y F+G N++V L F F++ C DY VK Y N S + +G +CG + + + S + + + F++ T + N+ GFK + F + + + + S C I + TG + SP YP +P T+ C IY + L R+RL+F FN+ + + C +++I + Q +D+ D D LCG + + S R L +V +G LQ GFK K+TF +Y+ IPGT C SS + G + SP + C+Y F+ + Q + ++ N C + +L +Y V + L+ RY +T P V S + L++ GFK Y F G C + ++++ GLI SP + Y ++++C + A+ + + F F D PA
Sbjct: 92 GALISPTYPGAYPKDMSCTYQFLGESNQRVRLEFRDFDLFFGGPHCPFDY------VKVYDGPDNSSAL------IGTYCGQQRNLV---LYSSESSLFVHFYTLSRTANTQNR-------GFKGIYEFSESFVKLDFIRENDGIHIRGSECDQKILSKKESTGFVLSPNYPYPYIPKTV-CRYFIYGMQDAQHLERVRLEFNAFNIPKVEHKDKSESNCTDGYLKIYLKGQETADAYDKFDYELCG-NETQRVISEGPR--LAMVFSSGE---------------LQGRGFKGKYTFETEYK-----------IPGTAAPDGTCSFTYVSSSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRDNNDRLLGRY---CGQTAPGPV-----------ESPRGAVGLRITLHTDQESVASGFKARYFF------ESAKSDAGDCGGNFSNQDS---GLITSPNWPAGYKAPGRGMASNACNWVMKARPGYKLSIHFEQFGLEGD-PA 562 HSP 3 Score: 57.3806 bits (137), Expect = 7.041e-8 Identity = 62/266 (23.31%), Postives = 106/266 (39.85%), Query Frame = 3
Query: 186 FYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEG-----------LSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY----TGEISSPTYP--------GLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQ--DEMCPVEFVEIINQPQLDSDSNDADNRLCGIK 908
+ S+ G L SP +P YP D Y+F+ +EQV + F+HF I+ S +C +D+L++Y+ + +R+ LGR+CG + P + S + L + + + D GFKA + F+ A S C G++ +G I+SP +P G+ + N + + R L+ + F F L + CP + + ++ DS+ LCG K
Sbjct: 368 YVSSSKKRGELNSPRYPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRDNNDRL-----------LGRYCGQT---APGPVESPRGAVGL--------RITLHTDQESVASGFKARYFFES--------AKSDAGDC------GGNFSNQDSGLITSPNWPAGYKAPGRGMASNACNWVMKARPGYKLS---IHFEQFGLEGDPANRGCPAAVLRL----WMNVDSDQPPLELCGEK 590
BLAST of Cubilin vs. Ensembl Fly
Match: Cubn (gene:FBgn0052702 transcript:FBtr0273437) HSP 1 Score: 94.3597 bits (233), Expect = 4.380e-19 Identity = 159/728 (21.84%), Postives = 269/728 (36.95%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYT---GEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNF----QFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGIS-GTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTD--SAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
T G L SP PG YP++ + + +++ L F +E + +C DY+ I + + L ++C P ++ ++ + F SD GF+ ++S + + G YT G IS + P ++C YE LA I F + D + +E ++I D + ++CG + F S NRL ++ AG F++ + + CD K+ + +G I SPG + + +IC Y NT + + +++F N E D D + + + + R K P CGKN + ++ S L+L+ + V +GFK YR L G + +R H R P + + Y ++C + A +N+ IRL + F V C DYL + + + + ++ +YCG S+P L+S + L L F S+ ++ GF +Y F + K CG +I ++S G + SP YP YS+ L C+WHL + + +F++E S +CS L + G CG D + IP + S+ +R+ TD G RGF++ W
Sbjct: 635 THGTLASPGSPGNYPKNRDCRWQLVAPTTKRIKLTFFSLQLEQHA-NCNFDYVLIKDSISGRE--------------LAKYCTTG---APAPLLLPTHLAEIHFHSDAEGS----------DTGFQLHYSVEER-----------------VPGCGGVYTAKEGTISESSTANTEPGGVSCEYEIH----LAVGEQVVIQFARLELDPLDCLEVLDIT-----DEGGSILQEKICGSDASRLNPPTFTSEFNRLKIKFYARAG--------------------SFQLNYRMA--------------------CDYKL---NNEQGTITSPGYPNLTRSDRICTYTISTATNTV-ISLKRIDFQLTN-GESDD----DDNDECLTTNLRINDGLNR-----KILGP---YCGKNQPEENFVSE--TNYLQLHLSTDVDSMGRGFKFEYRALATGNDKCGGVHTRSGDHIRL-------------PVHDDSYAGEATCYWVIMAPANKAIRLHWNSFSLENAV------------DCIYDYLEIYDSLGAQVNDERSKPLAKYCGNSVPEDLLSHSRQL--VLKFVSDYSESDGGFDLTYTFEDRAK-----CGGHIHASS--GELTSPEYPANYSAGLDCDWHLTG-TIDHLLEIQVENFELE-QSPNCSADYLEVRNGGGTDSPLIGRFCGRDIPARIPGF---SHEMRLILHTDSAING-RGFRLRW 1209 HSP 2 Score: 76.2554 bits (186), Expect = 1.334e-13 Identity = 131/568 (23.06%), Postives = 216/568 (38.03%), Query Frame = 3
Query: 588 FSFKYNEMITKYWASS------HHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGR---NYMMEPHNIDLYKSS-LQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSE---LCGTD 2252
F+ ++N + K++A + + +C Y ++ + G I+SP YP L S C Y S +T I L IDF L + +S+D DN C + N + NR L + N++ E + + L+ S+ + ++G KF + AL D G + +S D +I P + + C + M N + ++L++ +L D C YL IY S + +R +KP CG N + S + ++LK F + GF L+Y F R +C + G + SP Y Y + C + + ++ + F+ E P +C DYL V R G + R+CG IP + + L +++ NG GF + ++F+ CG ++ S G I SP YP Y + CEW + ++ P L ++EG S +C ++IY G + QS LC D
Sbjct: 827 FTSEFNRLKIKFYARAGSFQLNYRMACDYKLN---NEQGTITSPGYPNLTRSDRICTYTI-STATNTVISLKRIDFQL-------------------TNGESDDDDNDEC-LTTNLRINDGLNRKILGPYCGKNQPEENFVSETNYLQLHLSTDVDSMGRGFKFEY-------RALATGNDKCGG----VHTRSGD----HIRLPVHDDSYAGEATCYWVIMAPAN----KAIRLHWNSFSLENAVD--CIYDYLEIYD-SLGAQVNDER-------SKPLAKYCG-NSVPEDLLSHSRQLVLK--FVSDYSESDGGFDLTYTF----------EDRAKCGGHIHASS----GELTSPEYPANYSAGLDCDWHLTGTIDHLLEIQVENFEL-EQSP-----------NCSADYLEV-----RNGGGTDSPLIGRFCGRDIPARIPGFSHEM--RLILHTDSAINGRGFRLRW------RIFAFGCGGSLRSN--MGAISSPRYPNSYPNMAHCEWRI-SLHPGSGISLLIEDLELEGLS-NCYYDSVKIYTGIKLPNQSPCKVLCKDD 1295 HSP 3 Score: 67.781 bits (164), Expect = 5.891e-11 Identity = 151/711 (21.24%), Postives = 276/711 (38.82%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIG-FKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYP-SNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFIL----TFTSFQIEGTSKSCSNAVLRIYEG-FNVKPQ-SELCGTDSAIPSYFSSSNFIRVRFLTDIT 2318
G SP +P YP ++ +++ S + L E ++E S SC +DYL++ E +S + ++G +CG+ + + H+ I + F SD DD++G+ GF A+++++ HH+ NG+ G I SP +P + Y +R T+ + + I LY +D ++QP L+ F+ ++ + R+ V ++ N+ + S N G FK+ + K E L + NR +C ++ + D+S SPG + N F+ + + M V L + ++L E+ C Y+ I+S S + R + D+V G+ YL+ + + +P + + GF GI T SE T +GL+N P N C + + I++ F FQ ++ + + ++YL + ++ FL K YC + +L + F S P FL S++F + R ++D +S++ +I SP+YP C W + A P+ R +L F G + C + I +G ++P+ CG + + +S+ N +R+R+ TD++
Sbjct: 1801 GKFTSPYYPASYPPNIECLWLLEASMGNSLSLTLESMDLEK-SESCNRDYLEVREESESGQ-------------LIGVYCGNEVPGVIHS----RGAIWMKFKSD---------DDNVGE-GFMASYNYE------------HHN------ELNGT-EGTIESPHFPSKFQDPVP--YSWRI--TVDKEYVVAISL-LYLRD----------LDQPHLN------------------FYDGYSDIGARIEVTDPDETIISSTNVVYFTS---NRGPFKLNWNRLSK-EALRS--NRTAEERTRQCGNQLITIDRSVIGFHSPGYPNG--YEQDLNCFWTLVPSNPAMHAV-LTLSQIDL-EIFSEDCIADYVKIFSGSDLQNWSELRTLCSLPTESSDRVFHGRPYLRVEFVT-DPSV------------NKTGFN---------GIVRTACG---------SEITASKGLVNITEILKVLPRPNHDCVWTIKVRQGRRIKIDFPDFQLQNNMASGSSDC--------RNYLLLRNGNDEDSPFLGRGK---YCEDVVHEVLNTSSNKAYIKFHFASP-----PRFLVSFRFEELR--YTDSGRIRLSASGDEQFISSPYYPHLPHPHSECIWIVEA-PPEHRIMLHFQGAFDMLDATGEPEECQREFVLINDGSTELRPEIGRYCG-NRKPDTIYSTGNQMRIRYFTDVS 2370 HSP 4 Score: 67.781 bits (164), Expect = 6.357e-11 Identity = 74/276 (26.81%), Postives = 111/276 (40.22%), Query Frame = 3
Query: 1527 FLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSE----LCGTDSAIPSYF-SSSNFIRVRFLTD--ITSKGAR 2333
F D+ I G M E G G SP Y YP+N C + + + I L ED P +C +D LTV+ N ER+CG++ ++ S L + F S+ NG GF A+Y+ +K CG + T+ G I SP+YP Y + CEW + VS + + +E + C+ L Y+ + E +CG ++ SSSN VRF++D ++ KG R
Sbjct: 1430 FQLDYRIDGCM-----------EELRGTFGFFQSPNYPKMYPNNLECYWLITVEQDSAIELTINNIDL-EDSP-----------NCTKDALTVS------NHKNSVEVHERHCGSTTKLVITSSGHRL--HVRFISDNSHNGLGFEATYRTVKA------TCGGKL--TARNGVIESPNYPLNYPAHSRCEWQVE-VSQHHQIVFEMADLNLE-SGYDCNWDYLEAYDLTEDDTEGERLFKVCGDETEDDKLLSSSSNMAVVRFISDDSVSKKGFR 1664 HSP 5 Score: 51.2174 bits (121), Expect = 6.039e-6 Identity = 76/349 (21.78%), Postives = 123/349 (35.24%), Query Frame = 3
Query: 1413 GKNYLKYSYTSRN-----PVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTF---KSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQI------EGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGH 2417
G+ KY T P + +++F GF+L Y + + G C Y ++E G I+ N P SC+Y+ E + + F + D L V +I LQ E+ CG+ S+ FT F K + F +Y+ K+ ++Q G I SP YP SD IC + + + + L FQ+ + + C LRI +G N K CG + ++ S +N++++ TD+ S G RGF+ + + N C G + H
Sbjct: 694 GRELAKYCTTGAPAPLLLPTHLAEIHFHSDAEGSDTGFQLHYSVEER--VPG-------CGGVYTAKE----GTISESSTANTEPGGVSCEYEIHLAVGEQVVIQFARLELDP-----------------LDCLEVLDITDEGGSILQ----EKICGSD-----ASRLNPPTFTSEFNRLKIKFYARAGSFQLNYRMACDYKLNNEQ-----------GTITSPGYPNLTRSDRICTYTI-STATNTVISLKRIDFQLTNGESDDDDNDECLTTNLRINDGLNRKILGPYCGKNQPEENFVSETNYLQLHLSTDVDSMG-RGFKFEYRALA--TGNDKCGGVHTRSGDH 988
BLAST of Cubilin vs. Ensembl Zebrafish
Match: cubn (cubilin (intrinsic factor-cobalamin receptor) [Source:ZFIN;Acc:ZDB-GENE-060228-6]) HSP 1 Score: 124.02 bits (310), Expect = 5.342e-28 Identity = 164/714 (22.97%), Postives = 289/714 (40.48%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMK-YLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSN---FIRVRFLTDITSKG 2327
T GI++SPNWP Y + + +Y+ +EQV LNF H ++E + C D+ +EV+ +P++G++CG++L P I+S N + + F SD + + + GF+A + + S TG+I +P +P P C + + L+F+ F++ + C + VE+ + P S S+ R CG++ S+ ++++ A S+ N GF +F +++ C ++ + G SPG C ++ + +++L+F+Y N+ + C Y+ +Y + L+ R+ CG++ + S TS + ++ + L + E GF Y I+ T C +++ G ++SP Y + YP+N C Y + N I L F FQ L + SC DYL + R+ G+ + +YCGT+ P I+VS L + F+S+ GF A + + CG ++++S G SP+YP Y ++ C WH+ S R L+F F +E T C L +Y+G N ++LCG + IP+ SSS ++++R + I + G
Sbjct: 718 TEGIIISPNWPNNYAHNRQCIYIIRMPRSEQVALNFTHMDLE-IHTGCLFDF----VEVRDGTGET--------DPLIGKYCGNTL---PAPILSTTNGLWIRFQSDSS----------VSRAGFRAMYELACGGTL--------------------SGTGQIRTPFHPDPYPHNKVCEWVINQPEGYV-VTLNFLTFDV-EGSSTCAFDHVEVRDGP---SSSSPLIGRYCGVEMPPMLESTQKSMFIQFKTDA----------------SVSNHGFTAEFGSAEQ-----------------GCG---ETLTEPTGSFTSPGHPTEYPHGANCTWYI----SVPPGHLIRLSFSYFNMEFHTN--CAYDYVDVYDNGTALTGTLLGRF-------------CGRS-VPPSLTSTDSLMTVLLVSDSSLSAE--GFSADY-----ISINATT----DCSKVFRTS----TGELSSPNYPDNYPTNRECVYRIIVEVNMQIMLNFTDFQ--------LEGFS----SCGFDYLEI-----RDGGYETSPLIGQYCGTNAPPIIVSHSNRL--WMKFRSDHSLTYRGFQAHWDGTQT------GCGGTLTTSS--GGFTSPNYPLPYPANAECYWHIK-TSAGSRIQLSFGDFHLEDTVD-CYFDYLMVYDGNNSNAHQLAKLCG--NQIPAPISSSRENMYVKLRTDSIIHTGG 1278 HSP 2 Score: 109.383 bits (272), Expect = 1.507e-23 Identity = 173/765 (22.61%), Postives = 285/765 (37.25%), Query Frame = 3
Query: 96 ILAMRWDLFLMFLSITKIANSSIENIFY--EHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFI-DFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP--GRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKS-CSNAVLRIYEG--FNVKPQSELCGTDSAIPSYF-SSSNFIRVRFLTDITSKGARGFQIVWTRV 2360
I+ L++ FLS + + + +Y E + GG++ SP +P YP R ++ V L F +F +E S C D + I+ S P++G++CGH+ P I S +N +++ F +D + K GF A + S+ + C +IHA+ TG I SP YP P+ + C + + + + F DF + C ++++ +DN I+++ ++ ++A RN + S GF F T C + S G ++SP A CNY I N VV L F + F+ + +Y +K Y + P LCG N + +T+ P++I NF GF Y + G+ G G I SP ++ + Y N +C Y + ++N +I L F F + +C+ DY+ V + + ++CG +P L S + L F +++ G+ A+Y + CG +SS S G SP G+Y + C W + AV + LTF SF++EG++ + C + IY+G N CG IP+ F S+SNF+ V F++D T RGF ++ V
Sbjct: 2668 IVVSTPSLWVHFLSDEAVGDLGFKATYYFSECGGTQSGDGGVISSPGYPNVYPSPSRCTWLLEAPVGHTVVLTFTYFEVEEHS-QCVWDSVTIFNGASS------------GSPIIGQYCGHN---SPGTIRSGSNKLVVVFLADHT----------VSKGGFAATW-------------STDSTGCGGIIHAD---TGTIKSPNYPQNFPTNIECSWTIIAHDG-NHLEMGFASDFQIPDSSGQCQNSYIKMW-----------SDN----IQNDENLLATGCGTTAPAAIIAPRNVITA----RFQSSDTPGKGFSAAFY--------------------TTCGANFTA---SSGRVVSPNYPDHYPANSNCNY----IINAGEQFVVVLTF--------RTFQIEAHSTCVYDG-------VKIYSGTTASSSPLATLCG-NTIPGIFTTFGPMLI---NFYSDSIIHDNGFLAEYTTIPCGGVF-----------------NGTAGTIGSPSHSISNYHHNINCTYHIYVRNNRVINLKFNSFNL------------EASSTCNFDYVAVYDGESTLAPLMG-----KFCGHELPPNLRSSTNHM--FLQFVTDSSVAAEGWRATYSETLGPQ---QGCGGFLSSPS--GMFGSPDIDMNGQYEPHMDCMWTI-AVEVNKAINLTFISFELEGSTGTLCRYDHVTIYDGDSANFPLVGTFCG--DVIPAPFISASNFLTVHFISDGTVS-RRGFNATYSTV 3279 HSP 3 Score: 100.138 bits (248), Expect = 1.129e-20 Identity = 167/747 (22.36%), Postives = 278/747 (37.22%), Query Frame = 3
Query: 153 NSSIENIFYEHFYSNKMTGG-------ILLSPNWPGK-YPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIIN-----QPQLDSDSNDADNRLCG-IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI-CNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQV--LCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL----CGTDSAIPSYFSSSNFIRVRFL-TDITSKG 2327
++S+ +I ++ YS + GG ++ SP +PG YP + + G + L + F+++ S +C DY +E++ Y N S L LG+ CG++L P + + ++ + F SD + FS + I + C ++A G ISSP YP L P + C + R+ L D L Q C +FVEI+N P+LD RLCG + Q SS N + + SS+ N GF ++ S++ + N G SP + + + C + H+T + VV ++ +L + + E YL +R I + + + LCG+ P L ++F GFK +Y F + G ++G G+I+SP Y N YPS S C + A + L F F+ E H C D +T+ + + +YCG + PG + S L + F ++ + GF A++ S CG I + + G I SP+YP + +++ C W + A + + FQI +S C N+ ++++ N++ L CGT +A + + N I RF +D KG
Sbjct: 2330 DASVTHIGFKAKYSIAVCGGTYIGQNGVIRSPGFPGSNYPDNSNCEWYLEGPTGHYLTLTYTAFDLQS-SANCNSDY----VEIREY----NASGRL-----LGKHCGNNL---PAPMDTGDSFAYVKFVSDASAN--------------AGGFSLSFEASIEE---------CGGDLNAP---FGTISSPNYPNLYPHSRICRWSITVPQG-RRVTLTINDLRLEDQ-STCAFDFVEILNGLTPSAPRLD--------RLCGTVPAGTQVKSSGNTMTVIFST----------------DSSVSNGGFTADYS-SEESAVCGGILNE-------------------PGNFTSPDFGNGNYSNNLNCEWLIQNPHHTNSSIVVIIDELHLE----------------HHQTCEWDYL--EFRLDIGDHNGELLTRLCGQTPPSIPIVVSTPS--LWVHFLSDEAVGDLGFKATYYFSECGGT-----------------QSGDGGVISSPGYPNVYPSPSRCTWLLEAPVGHTVVLTFTYFEVEE------------HSQCVWDSVTIFNGASSGSPIIG-----QYCGHNSPGTIRSGSNKL--VVVFLADHTVSKGGFAATW------STDSTGCGGIIHADT--GTIKSPNYPQNFPTNIECSWTIIAHDGNHLEMGFASDFQIPDSSGQCQNSYIKMWSD-NIQNDENLLATGCGT-TAPAAIIAPRNVITARFQSSDTPGKG 2921 HSP 4 Score: 97.4413 bits (241), Expect = 7.156e-20 Identity = 178/770 (23.12%), Postives = 277/770 (35.97%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKS--SLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKP--QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV-----IPRLSNGSCPG 2393
L ++F S I+ + +Y++ ++ G G SP +PG+YP + V+ S + + F++E C D L++Y P L + C P + S N + + F SD + GF A W C + A +GEI SP YP P +C + ++ R+ +F D ++ Q C ++V I + P + + ++CG SS N +Y+ ++S SL + GF +F+ E +D G I SP + C++ I + V L+FT L EM + C + I + RY CG N L + TS + +++K V + +GF+ +Y M S C E G NSP Y + YP N C + + I+L FI+FQ L D C DYL + E G L R+CG S+P S + + F S++ +G GF R VFS G++I+ ++ G I SP YP Y ++ W + V + F IE +C L+IY+G + E CG P SS + I + F +D T G +GF I WT V +P + G+C G
Sbjct: 1379 LHIVFRSDMSISYRGFQMDWYQNGCGGELFGPVGTFNSPGYPGQYPMNRECVWHIHTSPGSSISITILEFDVE-YHPDCNYDKLEVY------------GGPDLSAPRLAQLCTTRPPSNPLQVSSTGNAVTVRFTSDA----------VVSGRGFNAT------------WVEVP-GGCGGSVTAP---SGEIHSPQYPSNYPDNADCSWVITVDAG-HRVFFNFTDLDIENQFS-CSYDYVAIHDGPH---EHSPLLAQVCGTSRPPPVTSSTNVIYV------------------CFRSDHSLNHRGFSAQFS---------------------EACGSFIVTDDVGGEIASPRYPYPYPPNQDCSWI---IRAQEPFNHVTLSFTDFEL-EMLNSNCTHDSVEILDGDNVQAPSVGRY-------------CGSN-LPHPVTSLSNAMVVKFVSDHAVGR--KGFRATY-----------MASTSGCGGLLNMES----GAFNSPNYPDVYPPNVECVWTLTSSPGNRIQLSFIMFQ--------LQPSSD----CSNDYLEIRE--GHSTGAL----VGRFCGDSLPTNYTSITGHI-LWIKFISDSSISGAGF---------RAVFSHLYGNDITGST--GLIASPLYPRTYPNNADYRWTV-TVDSDSHIQIQFLDIDIEDL-FNCLYDKLKIYDGPSTNSFLLGEFCGLTLPNP-VRSSGSAITLEFQSD-TVIGGKGFLIEWTAVQGSGPLPTIEPGACGG 1996 HSP 5 Score: 96.2857 bits (238), Expect = 1.756e-19 Identity = 169/710 (23.80%), Postives = 247/710 (34.79%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPV-EFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDF------KCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSP-FYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD 2312
L SP WP Y ++ +V S + V N ++E SC D LDI N S P++ + CG L P ++ S + ++L F SD + + GF A FS C +H + G +SSP YP LNC ++ R+ + F F + C +++E+ N P D +S RLCG F ++ N LY V S N G K F L D P GYI SP + S P+ N + I N E VQL+F DF C Y+ I LI R LCG ++S + L F GFK Y GT + G G+I SP F + YP NS+C++ + + L + F +C+ DY+ + E +G L ++CG ++P + S + + F S+A N GF S++ ++CG ++++ +G I SP+YP Y IC W + V R LT ++E S +C+ + I G LCGT A SS N + V F TD
Sbjct: 2007 LFSPGWPELYQHNLDCSWVIR-SPSSIVEFNLLSLDMED-EVSCLHDSLDIR------DGETNAS------PLIAKVCGRQL---PGSLHSTGDAMLLRFTSDGS----------INGRGFNATFS----------------RGCGGFLHTD---RGVLSSPQYPQNYKPNLNCNWQVMVTPGF-RVSVTFQSPFQVQGYGNQCSTGDYLELRNGP--DGNSPTLSGRLCGSNVPSTFQTTDNSLYAHFV------------------SDGSNEGNGFKLLFEAHSSACGGLIELNDGDP--------------PGYITSP--DYPSNYPQ--NIDCVWIITVPNGEAVQLDFE-------GDFYIEPHSGCLFDYIEIRDGPTSDADLIGR-------------LCGNTRPSTQHSSG---TTMYLRFRTDASVTHIGFKAKYSIAV---CGGTYI--------------GQNGVIRSPGFPGSNYPDNSNCEWYLEGPTGHYLTLTYTAFDLQSSA------------NCNSDYVEIREY--NASGRL----LGKHCGNNLPAPM-DTGDSFAY-VKFVSDASANAGGFSLSFE------ASIEECGGDLNAP--FGTISSPNYPNLYPHSRICRWSI-TVPQGRRVTLTINDLRLEDQS-TCAFDFVEILNGLTPSAPRLDRLCGTVPAGTQVKSSGNTMTVIFSTD 2561 HSP 6 Score: 93.2041 bits (230), Expect = 1.374e-18 Identity = 175/767 (22.82%), Postives = 281/767 (36.64%), Query Frame = 3
Query: 78 NYMIMLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTG-GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVII-----LKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGT---DSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
N + IL+ L++ F S + ++ + + YE ++G G + +P P YP + +V E V LNF F++EG S +C D++++ S P++GR+CG + P + S + + F +D + + GF A F S+ L GS+T SP +P P NC + + S IRL F FN+ + C ++V++ + + + R CG S+ + + + LV SSL GF S Y +NA T+C ++S G + SP + C Y + N Q + LNFT L C YL I +E LI +Y CG N P+I+ L + F +GF+ + + G GT+ + G SP Y YP+N+ C + + I+L F F + V C+ DYL V + ++ + CG IP + S ++++ L S H G FLA+Y C + + G I S +YP Y S C W + A TF +F++E S C +++Y+G N Q+ L GT + P+ +S + + F +D+ S RGFQ+ W
Sbjct: 788 NTLPAPILSTTNGLWIRFQSDSSVSRAGFRAM-YELACGGTLSGTGQIRTPFHPDPYPHNKVCEWVINQPEGYVVTLNFLTFDVEGSS-TCAFDHVEVRDGPSS------------SSPLIGRYCGVEM---PPMLESTQKSMFIQFKTDAS----------VSNHGFTAEF------------GSAEQGCGETLTEPTGSFT----SPGHPTEYPHGANCTW-YISVPPGHLIRLSFSYFNM-EFHTNCAYDYVDVYDNGT--ALTGTLLGRFCGRSVPPSLTSTDSLMTVLLVS----------------DSSLSAEGF------SADYISINAT---------TDCSKVFRTS---TGELSSPNYPDNYPTNRECVYRIIVEVNMQ----IMLNFTDFQLEGFS--SCGFDYLEIRDGGYETSPLIGQY-------------CGTN--------APPIIVSHSNRLWMKFRSDHSLTYRGFQAHWDGTQT-GCGGTLTTS--------------SGGFTSPNYPLPYPANAECYWHIKTSAGSRIQLSFGDFHLEDTV------------DCYFDYLMVYDGNNS-----NAHQLAKLCGNQIPAPISSSRENMYVKLRTDSIIHTGG--FLANYH---------STCNGMLIANRSRGMIESLNYPNDYPSHADCSWTIQAYM-GNTINYTFIAFEVE-QSDGCGYDHVKLYDGPN--DQANLIGTFCGNVPPPAGTTSGTSLHIVFRSDM-SISYRGFQMDW 1398 HSP 7 Score: 88.1965 bits (217), Expect = 5.094e-17 Identity = 165/723 (22.82%), Postives = 269/723 (37.21%), Query Frame = 3
Query: 207 GGILLSP----NWP-----GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
GGIL SP ++P G Y V +V N+ + + F F+IE S SC D+L ++ + V+G++CG + + FS N+ + + + DH G T W S L + G+I SP YPG P +C + L I F +L D C +F+EI D ++ L G ++ S+ + L+ G + + H+ S+ + GF I +T S ++ ++EG IISP + C Y I E V LNFT+++L E+ C ++ + + E LI +Y T P +L N L + S + V + GF+ Y +SGT G I +PF+ + YP N C++ ++ L F+ F DV T C D++ V R+ + RYCG +P +L S QKS+ + FK++A + GF A + ++ CG ++ + G SP +P Y C W++ +V P L+F+ F +E +C+ + +Y+ + L CG S PS S+ + + V ++D +S A GF
Sbjct: 476 GGILESPAGTFSYPNNPGTGDYDHQVSCAWVIRTDPNQILRITFPFFDIEN-SASCNFDFLQVHDGESASAF------------VIGKYCGSAAP--------------AELFSSHNSLYFWFRSDHSVSAG-----------GFTVAWQSQAPVCGGQLTNT----YGDIKSPGYPGNYPPNRDCYWTVNVNPGLL-ITFAFGTLSLEHHDN-CNFDFLEI-------RDGLLPEDSLLG-----KYCSTASPPPLQTT---GPSAWIHFHS----DFSISDRGFHITYTTSPSDPGCGGVFT------------------ETEGIIISPNWPNNYAHNRQCIY----IIRMPRSEQVALNFTHMDL-EIHT-GCLFDFVEVRDGTGETDPLIGKY---CGNTLPAPILSTTNGLWIRFQSDSSV-------------SRAGFRAMYELACGGTLSGT-------------------GQIRTPFHPDPYPHNKVCEWVINQPEGYVVTLNFLTF----DVEGSST--------CAFDHVEV-----RDGPSSSSPLIGRYCGVEMPPMLESTQKSM--FIQFKTDASVSNHGFTAEFGSAEQ------GCGETLTEPT--GSFTSPGHPTEYPHGANCTWYI-SVPPGHLIRLSFSYFNME-FHTNCAYDYVDVYDNGTALTGTLLGRFCGR-SVPPSLTSTDSLMTVLLVSD-SSLSAEGF 1045 HSP 8 Score: 81.6481 bits (200), Expect = 4.175e-15 Identity = 159/736 (21.60%), Postives = 284/736 (38.59%), Query Frame = 3
Query: 294 QVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVV--------------------LAGRNYMME--------PHNIDLYKSSL---QNIGFKIKFTFSDKYEPLNALYNR---------QDHIPGTECDIKIQSSDQSEGYIISPGINRAS-LAPKICNYFFMGIHNTQNMEVVQLNFTYLNL--PEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIK-----ETKPDQVLCGKNYL--KYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISG----TMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGS--NISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTS-FQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDIT 2318
V L+F F +E L+ +C D ++I ++ N+ P +GR+CG +L PH + S +N +++ F SD +G+ GF+A Y AS+ S C L++ +G +SP YP + P + C++ S S RI+L FI F L Q C +++EI + + R CG + N+ + H L+++ + + G ++ P+N D Y+ ++ + +I+F D + N LY++ + G C + + + +S G I+ + + K + + + + ++ L + F G+ +Y + + ++I+ ++++ D+V C + L + T+ +P+I P G + RF D I+G SRG + + RG+++SP Y Y N +C + + + F P ++ Y + + DYL E+ +G T + R CG+++P + SL F S+ G GF ++ S CG ++ GYI SP YP Y ++ C W + V E L F F IE S C + I +G LCG ++ + SS + +RF TD +
Sbjct: 1675 HVTLSFTDFELEMLNSNCTHDSVEI----------LDGDNV--QAPSVGRYCGSNL---PHPVTSLSNAMVVKFVSDH----------AVGRKGFRA-----------TYMAST--SGCGGLLNME---SGAFNSPNYPDVYPPNVECVWTLTS-SPGNRIQLSFIMFQL-QPSSDCSNDYLEI----REGHSTGALVGRFCGDSLPTNYTSITGH-ILWIKFISDSSISGAGFRAVFSHLYGNDITGSTGLIASPLYPRTYPNNAD-YRWTVTVDSDSHIQIQFLDIDIEDLFNCLYDKLKIYDGPSTNSFLLGEFCGLTLPNPVRSSGSAITLEFQSDTVIGGKGFLIEWTAVQGSGPLPTIEPGACGGTLVTGDTPQFLFSPGWPELYQHNLDCSWVIRSPSSIVEFNLLSLDMEDEVSCLHDSLDIRDGETNASPLIAKVCGRQLPGSLHSTGDAMLLRFTSDGSINGRGFNATFSRGCGGFLHTD-----RGVLSSPQYPQNYKPNLNCNWQVMVTPGFRVSVTF-------QSPFQVQGYGNQCST--GDYL---ELRNGPDGNSPT-LSGRLCGSNVPSTFQTTDNSL--YAHFVSDGSNEGNGFKLLFE------AHSSACGGLIELNDGDPPGYITSPDYPSNYPQNIDCVW-IITVPNGEAVQLDFEGDFYIEPHS-GCLFDYIEIRDGPTSDADLIGRLCG-NTRPSTQHSSGTTMYLRFRTDAS 2332 HSP 9 Score: 78.1814 bits (191), Expect = 4.886e-14 Identity = 164/727 (22.56%), Postives = 257/727 (35.35%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPST----LNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGIN-RASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTL--TFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G ++SPN+P YP + Y+ E V L F F IE S +C D + IY S L CG+++ I + ++++F+SD S D+ GF A ++ I G + G + P S +NC Y + I L F FNL + C ++V + D +S A + CG + SS N ++L+ V SS+ G++ T+S+ P C + S G SP I+ P + + + + + + + L F L C+ +++IY L+ T + P + N+L + S V ++GF +Y + C + + T I SP Y N YP +SC++ A S E +++ F + D SC ++L + + G + ++C V S G T+ TFKS A G GF SYQ +V+ + YGY+ SP +P Y +L C L A P+ FI L FTSF +E T SC+ L + G + CG P F SN + + F +D T+ GF+I WT
Sbjct: 2939 GRVVSPNYPDHYPANSNCNYIINAGEQFVVVLTFRTFQIEAHS-TCVYDGVKIY------------SGTTASSSPLATLCGNTIP----GIFTTFGPMLINFYSD-----SIIHDN-----GFLAEYT---------------------TIPCGGVFNGTAGTIGSPSHSISNYHHNINCTYHIYVRNNRV-INLKFNSFNL-EASSTCNFDYVAV-----YDGESTLAPLMGKFCGHELPPNLRSSTNHMFLQFVT----------------DSSVAAEGWRA--TYSETLGPQQG------------CGGFLSSP---SGMFGSPDIDMNGQYEPHMDCMWTIAV---EVNKAINLTFISFELEGSTGTLCRYDHVTIYDGDSANFPLVG---TFCGDVIPAPFISASNFLTVHFISDGTV-------------SRRGFNATYSTVNSL-----------CGGAFNATATSQT--ITSPLYPNAYPPFTSCRWVLDAPSQEGVKVSVQQF------------HLDTSQSCTSNFLEFKDFPVGDYG-----QAHKFCSAD---SHVPDFYSYGRTMHITFKSEAFMTGNGFSLSYQVAGCSRVYEQE----------YGYLKSPGWPDLYPHNLECSIVLQA--PQNSFISLFFTSFDVE-THPSCNFDYLEVRNGSTATSPLLGKHCGNTLPNP-VFPGSNELFIFFKSDFTTT-RNGFEITWT 3510 HSP 10 Score: 77.7962 bits (190), Expect = 7.712e-14 Identity = 150/679 (22.09%), Postives = 252/679 (37.11%), Query Frame = 3
Query: 342 SCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTY-LNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSP-HYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEG-FNVKP-QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVI 2363
+CE DYL+ +++ + + L R CG + IP IV + + F SD + +G LGFKA + F S C +G G ISSP YP + PS C + + + L F F + ++ C + V I N S + + CG S N+L +VV L ++ GF ++ T C I + G I SP + C++ + H+ ++E + F +P+ +CQ+ Y+ ++S + + + T T P ++ +N + + S + G S F G + T S G + SP Y + YP+NS+C Y A ++ L F FQ + H +C D + + + L T CG +IPGI + L + F S++ + GFLA Y I VF+ G+ I SP H Y ++ C +H++ R I L F SF +E +S +C+ + +Y+G + P + CG + P+ SS+N + ++F+TD +S A G++ ++ +
Sbjct: 2635 TCEWDYLEFRLDIGDHNGEL-----------LTRLCGQTPPSIP--IVVSTPSLWVHFLSD----------EAVGDLGFKATYYF---------------SECGGTQSGDG---GVISSPGYPNVYPSPSRCTWLLEAP-VGHTVVLTFTYFEV-EEHSQCVWDSVTIFNGA---SSGSPIIGQYCGHNSPGTIRSGSNKL---VVVF-------------LADHTVSKGGFAATWSTDS-----------------TGCGGIIHAD---TGTIKSPNYPQNFPTNIECSWTIIA-HDGNHLE---MGFASDFQIPDSSG-QCQNSYIKMWSDNIQNDENL--LATGCGTTAPAAIIAPRNVITARFQS----------------SDTPGKGFSAAFYTTCGANFTASS----------------GRVVSPNYPDHYPANSNCNYIINAGEQFVVVLTFRTFQI------------EAHSTCVYDGVKIYSGTTASSSPLAT-----LCGNTIPGIFTTFGPML---INFYSDSIIHDNGFLAEYTTIPCGGVFNGTAGT----------IGSPSHSISNYHHNINCTYHIYVR--NNRVINLKFNSFNLEASS-TCNFDYVAVYDGESTLAPLMGKFCGHELP-PNLRSSTNHMFLQFVTD-SSVAAEGWRATYSETL 3157 HSP 11 Score: 75.8702 bits (185), Expect = 2.353e-13 Identity = 146/640 (22.81%), Postives = 234/640 (36.56%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEH-FNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVL-GRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHAN-GSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI-CNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVA-EIVKRENGFLQTN-KTERYCGTSIPGILVSQQKSLGFTLT--FKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP-GRYSSDLICEW 2102
G+L SP +P Y ++ + M + +V + F+ F ++G C Y+E+++ + + P L GR CG + +P + +N + F SD + + + GFK F +H S+C LI N G G I+SP YP P ++C++ + A ++LDF + C +++EI + P D+ D RLCG SS +YLR A S+ +IGFK K++ + Y Q+ G I SPG ++ C ++ G + L +T +L C Y+ I + + L K CG N L + + +K F GF LS+ S C + G I+SP Y N YP + C++ + L +D+ L +D T A + V+ NG + + +R CGT G +Q KS G T+T F +++ + GF A Y + S CG ++ G SP + G YS++L CEW
Sbjct: 2117 GVLSSPQYPQNYKPNLNCNWQVMVTPGFRVSVTFQSPFQVQGYGNQCSTG---DYLELRNGPDG--------NSPTLSGRLCGSN---VPSTFQTTDNSLYAHFVSDGSNEGN----------GFKLLFE-------------AHSSACGGLIELNDGDPPGYITSPDYPSNYPQNIDCVWIITVPNGEA-VQLDFEGDFYIEPHSGCLFDYIEIRDGPTSDA---DLIGRLCGNTRPSTQHSSGTTMYLRFRTDA----------------SVTHIGFKAKYSIAV----CGGTYIGQN------------------GVIRSPGFPGSNYPDNSNCEWYLEG----PTGHYLTLTYTAFDL--QSSANCNSDYVEIREYNASGRLLGKH--------------CGNN-LPAPMDTGDSFAYVK--FVSDASANAGGFSLSFE-----------ASIEECGGDLNAP----FGTISSPNYPNLYPHSRICRWSITVPQGRRVTLTI----------------NDLRL---EDQSTCAFDFVEILNGLTPSAPRLDRLCGTVPAG---TQVKSSGNTMTVIFSTDSSVSNGGFTADYSSEE-----SAVCGGILNEP---GNFTSPDFGNGNYSNNLNCEW 2609 HSP 12 Score: 70.8626 bits (172), Expect = 8.462e-12 Identity = 88/326 (26.99%), Postives = 137/326 (42.02%), Query Frame = 3
Query: 1479 TQPVRKEQQGFKLSYRFLKDFGISG-----TMVS-RGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQS--ELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKN 2432
+ P++ G ++ RF D +SG T V G C T G I+SP Y + YP N+ C + + + F T D+ + SC DY+ + + + L + CGTS P + S + + F+S+ N GF A FS+ CGS I + G I SP YP Y + C W + A P L+FT F++E + +C++ + I +G NV+ S CG++ P S SN + V+F++D + G +GF+ + S C G + SG S N
Sbjct: 1484 SNPLQVSSTGNAVTVRFTSDAVVSGRGFNATWVEVPGGC----GGSVTAPSGEIHSPQYPSNYPDNADCSWVITVDAGHRVFFNF----TDLDI--------ENQFSCSYDYVAIHDGPHEHSPLLA-----QVCGTSRPPPVTSSTNVI--YVCFRSDHSLNHRGFSAQ---------FSEACGSFIVTDDVGGEIASPRYPYPYPPNQDCSWIIRAQEPFNHVTLSFTDFELEMLNSNCTHDSVEILDGDNVQAPSVGRYCGSNLPHP-VTSLSNAMVVKFVSD-HAVGRKGFRATY-----MASTSGCGGLLNMESGAFNSPN 1770 HSP 13 Score: 70.0922 bits (170), Expect = 1.393e-11 Identity = 73/284 (25.70%), Postives = 114/284 (40.14%), Query Frame = 3
Query: 1464 LKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKT-ERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRF 2303
+ + F GF LSY+ ++G C Y+ E G + SP + + YP N C A N I L F F + H SC+ DYL V NG T+ ++CG ++P + L + FKS+ GF ++ + CG + +G SP+YPG Y++ CEW + A P R + +TF I+ C N L++++G N CG ++ I + +SSN + V+F
Sbjct: 3376 MHITFKSEAFMTGNGFSLSYQ------VAG-------CSRVYEQE----YGYLKSPGWPDLYPHNLECSIVLQAPQNSFISLFFTSFDV------------ETHPSCNFDYLEV------RNGSTATSPLLGKHCGNTLPNPVFPGSNEL--FIFFKSDFTTTRNGFEITWTSSPQ------GCGGVLYGD--HGSFTSPNYPGTYANGSSCEWSIRA--PSGRVVTVTFNQISID-DPGDCQNNYLKLFDGPDANSPAVGPYCGLETNIAPFRASSNLVFVKF 3611 HSP 14 Score: 69.3218 bits (168), Expect = 2.392e-11 Identity = 72/272 (26.47%), Postives = 108/272 (39.71%), Query Frame = 3
Query: 1611 RGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGT-DSAIPSYFSSS-NFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSG 2414
RG+I S Y N YPS++ C + A I FI F+ + C D++ + + Q N +CG P + SL + F+S+ + GF + + + CG + G +SP YPG+Y + C WH+H SP +T F +E C+ L +Y G ++ ++LC T + P SS+ N + VRF +D G RGF W V G C G SG
Sbjct: 1297 RGMIESLNYPNDYPSHADCSWTIQAYMGNTINYTFIAFEVEQSD------------GCGYDHVKLYDGPND-----QANLIGTFCGNVPPPAGTTSGTSL--HIVFRSDMSISYRGFQMDW--------YQNGCGGELFGP--VGTFNSPGYPGQYPMNRECVWHIH-TSPGSSISITILEFDVE-YHPDCNYDKLEVYGGPDLSAPRLAQLCTTRPPSNPLQVSSTGNAVTVRFTSDAVVSG-RGFNATWVEVP-----GGCGGSVTAPSG 1531 HSP 15 Score: 63.929 bits (154), Expect = 1.245e-9 Identity = 78/301 (25.91%), Postives = 126/301 (41.86%), Query Frame = 3
Query: 1590 QSEETGYRGLINSPFYTNFYPSNS---------SCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCG---TDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFN 2456
Q+ + G++ SP T YP+N SC + N+++R+ F F SC+ D+L V + + + F+ +YCG++ P L S SL F F+S+ + GF ++Q + V CG +++T YG I SP YPG Y + C W ++ V+P F + +E +C+ L I +G + P+ L G + ++ P ++ + F +D S RGF I +T S+ C G G IS N N N
Sbjct: 469 QTPQQECGGILESPAGTFSYPNNPGTGDYDHQVSCAWVIRTDPNQILRITFPFFDIENSA------------SCNFDFLQVHD-GESASAFV----IGKYCGSAAPAELFSSHNSLYFW--FRSDHSVSAGGFTVAWQ--SQAPV----CGGQLTNT--YGDIKSPGYPGNYPPNRDCYWTVN-VNPGLLITFAFGTLSLE-HHDNCNFDFLEIRDG--LLPEDSLLGKYCSTASPPPLQTTGPSAWIHFHSDF-SISDRGFHITYTT---SPSDPGCGGVFTETEGIIISPNWPNNYAHN 734 HSP 16 Score: 59.6918 bits (143), Expect = 2.123e-8 Identity = 63/252 (25.00%), Postives = 107/252 (42.46%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEM--CPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQ-FFSSHNRLYLRL 956
G L SP WP YP ++ V +N + L F F++E SC DYL++ +N ++ P+LG+ CG++L P+ + +N + + F SD T + GF+ W SS L +GS+T SP YPG + +C + R+ S R+ + FN D+ C ++++ + P +S A CG++ N F +S N ++++
Sbjct: 3409 GYLKSPGWPDLYPHNLECSIVLQAPQNSFISLFFTSFDVE-THPSCNFDYLEV-------RNGSTATS-----PLLGKHCGNTL---PNPVFPGSNELFIFFKSDFTTT----------RNGFEIT------------WTSSPQGCGGVLYGDHGSFT----SPNYPGTYANGSSCEWSIRAPSG----RVVTVTFNQISIDDPGDCQNNYLKLFDGPDANS---PAVGPYCGLETNIAPFRASSNLVFVKF 3611
BLAST of Cubilin vs. Ensembl Zebrafish
Match: pcolce2a (procollagen C-endopeptidase enhancer 2a [Source:ZFIN;Acc:ZDB-GENE-070705-25]) HSP 1 Score: 80.8777 bits (198), Expect = 1.851e-15 Identity = 66/251 (26.29%), Postives = 110/251 (43.82%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGR-YSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
TG G+I S Y YP N+ C + ++ L+F V D C D++ V + G + + R+CGT+ P LV+ + + S+A+ G GFLA Y I+ + CG + S G I +P++P + Y + C WH+ V+P ++ I L F F +E S +C + ++ G ++ CG +P + S + + + FL+D+ S A GF
Sbjct: 34 TGDTGMIGSQGYPAVYPPNNKCVWRITVPQGRLVSLLFRVLDLESDS------------LCRYDFVDVYD------GHINGQRLGRFCGTAKPRALVTNGNKMQVVMV--SDANTAGSGFLAVYSAIRPNERVDRYCGGLLDKPS--GTIKTPNWPDKDYPPGVTCSWHI--VAPLDQIIELKFEKFDVERDS-NCRYDHVAVFNGGETNETRKIGKFCGDSPPMPIH-SDGHHLLITFLSDL-SLTADGF 257
BLAST of Cubilin vs. Ensembl Zebrafish
Match: pcolce2a (procollagen C-endopeptidase enhancer 2a [Source:ZFIN;Acc:ZDB-GENE-070705-25]) HSP 1 Score: 80.4925 bits (197), Expect = 2.297e-15 Identity = 66/251 (26.29%), Postives = 110/251 (43.82%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGR-YSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
TG G+I S Y YP N+ C + ++ L+F V D C D++ V + G + + R+CGT+ P LV+ + + S+A+ G GFLA Y I+ + CG + S G I +P++P + Y + C WH+ V+P ++ I L F F +E S +C + ++ G ++ CG +P + S + + + FL+D+ S A GF
Sbjct: 52 TGDTGMIGSQGYPAVYPPNNKCVWRITVPQGRLVSLLFRVLDLESDS------------LCRYDFVDVYD------GHINGQRLGRFCGTAKPRALVTNGNKMQVVMV--SDANTAGSGFLAVYSAIRPNERVDRYCGGLLDKPS--GTIKTPNWPDKDYPPGVTCSWHI--VAPLDQIIELKFEKFDVERDS-NCRYDHVAVFNGGETNETRKIGKFCGDSPPMPIH-SDGHHLLITFLSDL-SLTADGF 275
BLAST of Cubilin vs. Ensembl Zebrafish
Match: pcolce2b (procollagen C-endopeptidase enhancer 2b [Source:ZFIN;Acc:ZDB-GENE-040426-1177]) HSP 1 Score: 78.5666 bits (192), Expect = 9.371e-15 Identity = 67/244 (27.46%), Postives = 104/244 (42.62%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGR-YSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNV---KPQSELCGTDSAIPSYFSSSNFIRVRFLTDIT 2318
TG G+I S Y YP N+ C + ++ L F D +L C DY+ V +G + R+CGT PG LVS + + S+A+ G GFLA Y + CG + S G+ +P++P R Y + + C WH+ V+PK + I + F F +E C + I+ G + K + CG P FS N + ++FL+D++
Sbjct: 33 TGESGVIGSQGYPGVYPPNTKCVWRITVPEGKVAVLTFRFLDLESD-----------NL-CRYDYVDV------YSGHGNGQRLGRFCGTFRPGALVSTSNKM--LMQMVSDANTAGSGFLAVYSAANPNERGDQYCGGRLMKPS--GFFKTPNWPERDYPAGVTCSWHI--VAPKNQIIEVKFEKFDVE-RDNYCRYDYVAIFNGGEINDAKRIGKYCGDTPPAP-VFSEGNQLFIQFLSDLS 250 HSP 2 Score: 58.151 bits (139), Expect = 3.388e-8 Identity = 62/254 (24.41%), Postives = 107/254 (42.13%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKY-NEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGL-LPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLV 959
G++ S +PG YP + + V+ E + L F ++E + C DY+D+Y + + LGRFCG F P +VS +N +++ SD NT S GF A +S NE +Y L+ +G + +P +P P+ + C + + I + F F++ ++D C ++V I N ++ NDA + CG FS N+L+++ +
Sbjct: 37 GVIGSQGYPGVYPPNTKCVWRITVPEGKVAVLTFRFLDLESDNL-CRYDYVDVYSGHGNGQR-------------LGRFCG---TFRPGALVSTSNKMLMQMVSDANTAGS----------GFLAVYSAANPNERGDQYCGGR-------LMKPSGFF----KTPNWPERDYPAGVTCSWHIVAPKNQI-IEVKFEKFDV-ERDNYCRYDYVAIFNGGEI----NDAKRIGKYCGDTPPAPVFSEGNQLFIQFL 246
BLAST of Cubilin vs. Ensembl Zebrafish
Match: pcolce2b (procollagen C-endopeptidase enhancer 2b [Source:ZFIN;Acc:ZDB-GENE-040426-1177]) HSP 1 Score: 78.5666 bits (192), Expect = 9.371e-15 Identity = 67/244 (27.46%), Postives = 104/244 (42.62%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGR-YSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNV---KPQSELCGTDSAIPSYFSSSNFIRVRFLTDIT 2318
TG G+I S Y YP N+ C + ++ L F D +L C DY+ V +G + R+CGT PG LVS + + S+A+ G GFLA Y + CG + S G+ +P++P R Y + + C WH+ V+PK + I + F F +E C + I+ G + K + CG P FS N + ++FL+D++
Sbjct: 33 TGESGVIGSQGYPGVYPPNTKCVWRITVPEGKVAVLTFRFLDLESD-----------NL-CRYDYVDV------YSGHGNGQRLGRFCGTFRPGALVSTSNKM--LMQMVSDANTAGSGFLAVYSAANPNERGDQYCGGRLMKPS--GFFKTPNWPERDYPAGVTCSWHI--VAPKNQIIEVKFEKFDVE-RDNYCRYDYVAIFNGGEINDAKRIGKYCGDTPPAP-VFSEGNQLFIQFLSDLS 250 HSP 2 Score: 58.151 bits (139), Expect = 3.388e-8 Identity = 62/254 (24.41%), Postives = 107/254 (42.13%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKY-NEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGL-LPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLV 959
G++ S +PG YP + + V+ E + L F ++E + C DY+D+Y + + LGRFCG F P +VS +N +++ SD NT S GF A +S NE +Y L+ +G + +P +P P+ + C + + I + F F++ ++D C ++V I N ++ NDA + CG FS N+L+++ +
Sbjct: 37 GVIGSQGYPGVYPPNTKCVWRITVPEGKVAVLTFRFLDLESDNL-CRYDYVDVYSGHGNGQR-------------LGRFCG---TFRPGALVSTSNKMLMQMVSDANTAGS----------GFLAVYSAANPNERGDQYCGGR-------LMKPSGFF----KTPNWPERDYPAGVTCSWHIVAPKNQI-IEVKFEKFDV-ERDNYCRYDYVAIFNGGEI----NDAKRIGKYCGDTPPAPVFSEGNQLFIQFL 246
BLAST of Cubilin vs. Ensembl Xenopus
Match: wdr81 (WD repeat domain 81 [Source:Xenbase;Acc:XB-GENE-6258221]) HSP 1 Score: 104.375 bits (259), Expect = 7.872e-22 Identity = 180/769 (23.41%), Postives = 288/769 (37.45%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPV-EFVEIINQPQLDS---DSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLS--CHQDYLTVAEIVKRENGFLQTNKTER----YCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF-NVKP-QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNG----------SCPGFQCLNSGHCISKNLTCNKVF 2453
L SP WP Y + +V + + V LN +IE SC D L I R +N + P L CG +P I S + + + F +D + + GF A S+H SC +HAN G I+SP YP + LNC + F S F + D C +++E+ N P S ++ + + CG ++ N +++ V +S + GF++K YE L+ I I SD S G++ SP C + I N E V+L F E + C YL + + K L+ + LCG N L +Y S + L+ F + GFK Y+ + + G H+ G G+I SP Y YP NS C++ F + + + F D+H S C +D++ + E N + R +C + +P LV+ S + + F S+ +NG GF Y +++CG + +++S G I SP+YP Y + +CEW + V R LT + ++ ++C + +Y G+ N P +LCG + SS N +RV F+TD S + GF + + + G S PG+ +N+ ++NL C +
Sbjct: 1966 LFSPGWPNNYASYLDCTWV-IKAPGSTVELNILSVDIEKHR-SCNYDKLVI---------RDGDNN---NSPQLAVVCGKG---VPGPIRSSGDSMFIRFSTDGS----------VSGTGFNA----------------SYHKSCGGYLHAN---RGLITSPNYPEHYSANLNCTWHFLVTSGFTIAAHFEPTFEIPNSDSTCGTGDYLELKNGPDDSSPPMGTSTRNGKFCGTSAPSTMHTTDNEMFVHFVS----------------DNSNEGKGFQLK------YEALSLACGGS---------IYISESDPS-GFVTSPKYPENYPMNADCVW----IITVPNGEAVELEFKEQFYIEPSE-NCSSNYLELRDGADASKRLLAK-------------LCG-NALPITYKSLGTAMYLR--FMTDSGTPRVGFKAMYK----------IATCGGTHF-------GQSGIIQSPGYPLQNYPDNSLCEWYFTGPTGHYLTIQFEAM--------------DLHNSTDCSRDFVEIREY----------NASGRILGVFCNSMVPSDLVTSD-SFAY-IKFVSDQSENGRGFRIRYD------ASTEECGGDYTASS--GIISSPNYPNLYPHNRVCEWRI-TVPAGRRVTLTINALLLQ-DQQNCDYDYVAVYNGYQNQSPLLRKLCGNVAPETEVKSSGNTMRVIFVTD-GSVSSGGFLATFNSMEDAVCGGALADPTGGHFSSPGYDQVNN---YTRNLNCEWII 2578 HSP 2 Score: 100.138 bits (248), Expect = 1.357e-20 Identity = 167/739 (22.60%), Postives = 275/739 (37.21%), Query Frame = 3
Query: 147 IANSSIENIFYEHFYSNKMTGGI-------LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQL--NFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSP--HYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKS-CSNAVLRIYEGFNVKP--QSELCGTDSAIPSYFSSSNFIRVRFLTD 2312
++N+ +ENI + YS GGI + SPN+P Y ++ E + L+F HF+IE C D + I ++ P++G+FCG + P I S +N +++ F N DD + GF AN++ S C +HA+ +G I SP +P P+ C + + ++ + L F + F++ + C +V++ + + L ++ P N+ I+ TF + P + + I ++C +S G I+SP CNY IH NM +V NF + C L I+ + T P LCG + + S ++R + LNF GF +YR + GT + G + SP Y Y +N +C Y + N++I L F + SC DY+ V + + + L RYCG +P IL S +L L F ++ H G+ A++ R+ G T+ G SP + GRY S+L C WH+ ++P I LTF++F +E S+S C +++++G Q CG+ P + S+SN + V F++D
Sbjct: 2645 VSNAEVENIGFNASYSFTDCGGIQAGEYGVIASPNFPASYNSMSHCAWLLDAPEGHIITLSFIHFDIESHQI-CRWDSVTI------------LNGASPGSPLIGQFCGTTS---PGTIQSGSNKLLVIF----------NSDDSLHGRGFYANWT-------------SDSLGCGGHVHAD---SGTIRSPAWPQHFPANSRCTWTIETHAS-SHYELSFNNNFHIPDDNGHCQRSYVKV-------------------------WSGAEEELLATGCGDTAPAPVISPRNV-------------IRVTFQSQDAPGSGFF--ASFI--SKCGANFTNS---SGRIMSPNYPNKYGNNLRCNYT---IHAEANMFIVLFFQNFE-VECKSKTSLSCSKDGLKIFGG---------------ERTSPLANLCGAS-VPASISARGS---MSLNFYTDSDINMHGFMATYRVIP---CGGTFNAS--------------YGTLRSPTYAFTDYHNNMNCTYHVTVQENKIIELKFNELDL------------EASSSCLYDYIAVYDGLNSSSPLLG-----RYCGNVLPPILRSSSNNL--FLLFVTDNHITSRGWRATF-----RQTLGPMQGCGGYLTNAAGTFGSPDSNLDGRYDSNLNCAWHI--IAPINTQINLTFSAFFLEAQSRSTCRYDYVKVFDGSTTDSNLQGTYCGSSRPAP-FLSTSNVLTVLFVSD 3228 HSP 3 Score: 96.2857 bits (238), Expect = 2.109e-19 Identity = 160/725 (22.07%), Postives = 277/725 (38.21%), Query Frame = 3
Query: 207 GGILLSPNWPGKYPQDVRYVYVFMGSEN-EQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNA-VLRIYEGFNVKP--------QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQI 2345
G + SP +P YP + +++ E V L+F IE + +C DY++I ++ +N PV GR+CG + IPH I S +N +++ F S+ +T GF A F+ + S+C +H TG +SP+YP P+ C++ S S R+ L F Q + C +++EI + +++ R CG + N + H L+++ V SL GF+ F+ H+ G + G I SP R P NY + N + +++Q +++ + C L IY ++I Y + T P + + + +TS N + +GF L + + F + ++ G C ++ +T + SP + N Y S C + A + + I V D+ + H SC+ D L + R+ + + CG +PG + S S+ + F ++ +G GF ASY CG + + G I SP+YP YS++L C WH S +F+I + +C L + G + + CGT SA + ++ N + V F++D +++G +GFQ+
Sbjct: 1606 GATISSPLYPANYPNNQNCMWIIQAQEPYNHVTLSFTDLEIEFRNDNCTLDYVEI----------LDGNNP--DAPVQGRYCGRT---IPHPITSFSNALVVKFISNNSTS----------AKGFHATFA-------------ASTSACGGTLHME---TGAFNSPSYPENYPANTECVWNILS-SPGNRLLLTF----SVQHSDSCSHDYLEI----REGNETGSLMGRFCGDILPSNITTITGH-ILWIKFVS----------------DGSLSGSGFQATFS----------------HLFG-------NNIGGDRGQIASPLWPRN--YPHYSNYLWK--INVDSSQIIQARILEIDIEDHS--GCIYDKLKIYDGPDTHYHVIGTYCGI---TPPPDIFSSGSSMTVQFTSDNSI-------------NMKGFLLEWLAVDAFSENFPTIAPGACGGILRTGDTPL--FLFSPGWPNNYASYLDCTWVIKAPGSTVELNILSV-----DI--------EKHRSCNYDKLVI-----RDGDNNNSPQLAVVCGKGVPGPIRSSGDSM--FIRFSTDGSVSGTGFNASYH---------KSCGGYLHANR--GLITSPNYPEHYSANLNCTWHFLVTSGFTIAAHFEPTFEIPNSDSTCGTGDYLELKNGPDDSSPPMGTSTRNGKFCGT-SAPSTMHTTDNEMFVHFVSDNSNEG-KGFQL 2183 HSP 4 Score: 92.8189 bits (229), Expect = 2.355e-18 Identity = 164/725 (22.62%), Postives = 284/725 (39.17%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIV-SKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEM--CPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSK---SCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIP 2366
GI+ SPN+P YP + + +V L ++ +C+ DY+ +Y Y+N+ P+L + CG + P V S N + + F +D + + GF A F N M + L G G SSP Y + T N E+ ++ FI F Q + C +F+E+ + D+ + RLCG N + L ++A + ++ N ++ +NIGF ++F+D C IQ+ + G I SP + + C + + ++ L+F + ++ + C+ ++I + + LI ++ T P + G N L + S + + +GF ++ S ++ G H G I SP + +P+NS C + ++ L F + +P D + C + Y+ V + E L T CG + P ++S + + +TF+S G GF AS FI K CG+N +++S G I SP+YP +Y ++L C + +HA + +L F +F++E SK SCS L+I+ G P + LCG +++P+ S+ + + F TD + GF + RVIP
Sbjct: 2436 GIISSPNYPNLYPHNRVCEWRITVPAGRRVTLTINALLLQDQQ-NCDYDYVAVY---NGYQNQ---------SPLLRKLCG---NVAPETEVKSSGNTMRVIFVTDGS----------VSSGGFLATF----NSMEDAVCGGA-------LADPTG---GHFSSPGYDQVNNYTRNLNCEWIIQNPNTENSTTFISFKRLQLEYHLNCQRDFIEL----RFDNADGELITRLCG----------RNTPSVPLAIVASQVWVHFVSNAEV-----ENIGFNASYSFTD-------------------CG-GIQAGEY--GVIASPNFPASYNSMSHCAWLL----DAPEGHIITLSFIHFDIESHQ--ICRWDSVTILNGASPGSPLIGQF---CGTTSPGTIQSGSNKLLVIFNSDDSL-------------HGRGFYANW-------TSDSLGCGGHVHAD--------SGTIRSPAWPQHFPANSRCTWTIETHASSHYEL---SFNNNFHIP-------DDNGHCQRSYVKVWSGAEEE--LLATG-----CGDTAPAPVISPRNVI--RVTFQSQ-DAPGSGFFAS--FISK-------CGANFTNSS--GRIMSPNYPNKYGNNLRCNYTIHAEA-NMFIVLFFQNFEVECKSKTSLSCSKDGLKIFGGERTSPLANLCG--ASVPASISARGSMSLNFYTD-SDINMHGFMATY-RVIP 3006 HSP 5 Score: 92.4337 bits (228), Expect = 3.167e-18 Identity = 167/711 (23.49%), Postives = 253/711 (35.58%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIE---GLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGE--ISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIY-SVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD 2312
G + SP WP Y + + +Y+ NE++ L F + +E G S S Y+EV+ Y N IP I S +N + + F SD + S FKA FY + G TG I +P YP C + ++ + L F F++ C FVEI D S+D+ + CG + S+ LY+R SS N GF I + Q I G + ++G I SPG C +F + +++L F NL + C YL IY S S M+ I R+ CG++ + S TSR + + L +GF Y L + C Y T G+ +SP Y N YP+N C Y ++N+ I L F F S +C +D++ + R+ G+ + ++C P ++VS L + F+S++ + GF A + + CG ++S S G SP++P Y + C W + A S F + F F +E S C N L +Y+G +LCG P S SN + V+F TD
Sbjct: 705 GFISSPRWPQPYTGNKQCIYIIQQPANEKISLRFTNLELENSSGCSLS--------YMEVRIYCNTT----------------------IPPPISSSSNALWIKFKSDASVTRS----------SFKA----------------------FYQVACGGFLTGAGVIHTPHYPDAYFRERTCEW-IITQPEGEVVSLTFNSFDILAGTN-CGSNFVEI-----RDGSSSDSPLIGKYCGPEMPVPAQSTQRALYIRFTT----------------DSSATNHGFSISY---------------QSLIEGCGGTLT-----DTQGTITSPGYPAVYPHGIQCTWFI----SIPPGNLIRLTFDSFNL--EHGYSCSYDYLDIYDSASAIMESRIGRF-------------CGRS-IPPSITSRGNTMTVLL--VTDTNTAVEGFSARYTSLN---------ATTACDASY----TEASGIFSSPNYPNRYPNNLECIYTITVETNKQILLNFTTFVLSTST------------NCDKDHVEI-----RDGGYEISPLLGKFC-QGPPPVIVSHSNKL--WVKFRSDSSYSETGFSAHWDSA------TTGCGGTLTSVS--GGFTSPNFPMPYYHNSECYWQMMASS-GSTFEIQFEHFDLESHSN-CQNDYLAVYDGNTTHSHLLEKLCGKRLPDPIRSSGSN-VYVKFRTD 1244 HSP 6 Score: 87.4261 bits (215), Expect = 1.204e-16 Identity = 163/724 (22.51%), Postives = 263/724 (36.33%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIE---GLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYT---GEISSPTYPGL-LPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G ++SPN+P KY ++R Y N + L F++F +E S SC KD L I+ ++ L CG S +P +I ++ + + L+F++D + GF A + +I G++ G + SPTY + +NC Y + I L F + +L + C +++ + + L+S S+ R CG SS N L+L V + + + G++ TF P+ + GT S D + +N C + + NTQ + L F+ L C+ Y+ ++ S L Y ++P L N L + S + V E+QGF SY KD C Y + T +SP + N YP +SC + A E ++L F+ D C Q+Y+ + + + + RYCGT GI + FKS + G GF+ +YQ + ++ +GY+ SP +P Y + C L A P L F SF IE TS S L + G + + CG D+ FS +N +R+ F +D+ +RG++I WT
Sbjct: 2901 GRIMSPNYPNKYGNNLRCNYTIHAEANMFIVLFFQNFEVECKSKTSLSCSKDGLKIFGGERTSP--------------LANLCGAS---VPASISARGS-MSLNFYTDSDINMH----------GFMATYR---------------------VIPCGGTFNASYGTLRSPTYAFTDYHNNMNCTYHVTVQENKI-IELKFNELDL-EASSSCLYDYIAVYDG--LNS-SSPLLGRYCGNVLPPILRSSSNNLFLLFVT----------------DNHITSRGWRA--TFRQTLGPMQGCGGYLTNAAGT-----FGSPDSNLDGRYDSNLN--------CAWHIIAPINTQ----INLTFSAFFLEAQSRSTCRYDYVKVFDGSTTDSNLQGTY---CGSSRPAPFLSTSNVLTVLFVSDSSV-------------ERQGFNASY-VTKDL----------LCGGSYNATST--SVTTSSPNFPNLYPPFTSCMWIIDAPVKEHVKLSVQSFRLQTDG------------DCSQNYIELKDSPGDQ------GQVHRYCGTETFGIPDFYSYGQTAVVVFKSQNYMQGNGFIFTYQTANCSREYNQT----------FGYLKSPGWPENYPHNAECTTVLRA-PPNHTISLFFNSFSIEATSSSICYDFLEVRNGSDSNSPLIGKYCG-DTLPDPIFSKNNVLRLFFKSDLVLS-SRGYEITWT 3475 HSP 7 Score: 76.6406 bits (187), Expect = 1.918e-13 Identity = 99/390 (25.38%), Postives = 150/390 (38.46%), Query Frame = 3
Query: 1257 QLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVS-RGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGT-DSAIPSYFSSS-NFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG-FQCLN 2408
++ F + +L + CQ+ YL++Y + +L+++ LCGK P+R + +R SG + + C + + RG++ S Y N YP N C + A I F F + + SC+ DY+ + + ++ + T YCG +P + SL + F S+ PGF + + + + CG +S +G SP +P RY + C WH+ SP +T F IE S +CS VL IY G V ++LC P SS+ N + VRF TD G RGF W R IP G C G FQ N
Sbjct: 1186 EIQFEHFDLESHSN--CQNDYLAVYDGNTTHSHLLEK-------------LCGKR------------------LPDPIRSSGSNVYVKFRTDNSISFSGFFATYKQTCQGVMIANRS--RGILESLNYPNSYPHNQQCNWTIQATLGNTINYTFTTFNV------------EGYFSCN-DYVQLYDGPDKQARLIGT-----YCGNQLPPSGTTTGTSL--HVVFHSDDTITRPGF--------QMQWYVNGCGEELSGP--FGSFTSPGFPMRYPDNRECIWHIQ-TSPGSSIQITIWEFNIEYHS-TCSYDVLEIYGGPGVSSPRLAQLCAPRPQENPLQVSSTGNTMTVRFKTDAYVSG-RGFNTTW-REIP----GGCGGVFQAPN 1502 HSP 8 Score: 75.485 bits (184), Expect = 4.465e-13 Identity = 167/771 (21.66%), Postives = 271/771 (35.15%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAI---PSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV------IPRLSNGSCPGF 2396
L ++F S I + +Y + +++G G SP +P +YP + ++ S + + FNIE S +C D L+IY P L + C P + S N + + F +D ++ GF + E+ C + A GEI SP YP C + R + R+ L F DF++ + C + V + LCG + S+ N +++RL S Q+ GF KFT E +L + S G IS + A+ P N ++ I + V L+FT L + E ++ C Y+ I + + RY CG+ + + TS + +++K F +GF ++ + T G H G NSP Y YP+N+ C ++ + + L F V Q S+ SC DYL + E E G L R+CG +P + + + + F S+ +G GF A++ + + D+ G I SP +P Y W ++ V + IE S C L+IY+G + + GT I P FSS + + V+F +D S +GF + W V P ++ G+C G
Sbjct: 1351 LHVVFHSDDTITRPGFQMQWYVNGCGEELSGPFGSFTSPGFPMRYPDNRECIWHIQTSPGSSIQITIWEFNIEYHS-TCSYDVLEIY------------GGPGVSSPRLAQLCAPRPQENPLQVSSTGNTMTVRFKTDA----------YVSGRGFNT----TWREI---------PGGCGGVFQAP---NGEIHSPNYPRPYEDNTECSWVIRVDFG-HRVLLTFRDFDI-ESHSSCSFDSVTVT--------------VLCGTQLPAAISSTQNTMFVRL----------------RSDGSNQHRGFSAKFT-----EACGSLI-----------------TADSIGATISSPLYPANY-PNNQNCMWI-IQAQEPYNHVTLSFTDLEI-EFRNDNCTLDYVEILDGNNPDAPVQGRY-------------CGRT-IPHPITSFSNALVVK--FISNNSTSAKGFHATF-------AASTSACGGTLHME--------TGAFNSPSYPENYPANTECVWNILSSPGNRLLLTFSV-QHSD--------------SCSHDYLEIRE--GNETGSLM----GRFCGDILPSNITTITGHI-LWIKFVSDGSLSGSGFQATFSHLFGNNIGGDR-----------GQIASPLWPRNYPHYSNYLWKIN-VDSSQIIQARILEIDIEDHS-GCIYDKLKIYDGPDT--HYHVIGTYCGITPPPDIFSSGSSMTVQFTSD-NSINMKGFLLEWLAVDAFSENFPTIAPGACGGI 1956 HSP 9 Score: 75.0998 bits (183), Expect = 6.367e-13 Identity = 160/720 (22.22%), Postives = 278/720 (38.61%), Query Frame = 3
Query: 204 TGGILLSPNWP--GKYPQDVRYVYVFMG--SENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP-GRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD--ITSKGARG 2336
TGG SP + Y +++ ++ +EN ++F+ +E +C++D++++ + + ++ R CG + +P IV+ + + F S+ + +GF A++SF I G Y G I+SP +P S +C + + I L FI F++ + ++C + V I+N S + + CG S N+L LV+ N D SL GF +T SD C + + G I SP + A C + + H + + E+ N ++P+ + CQ Y+ ++S + E + T +T P V+ +N ++ ++ S++ GF S+ IS +C + T G I SP Y N Y +N C Y A++N I L F F+ + LSC +D L + G +T+ CG S+P + ++ +L F +++ N GF+A+Y+ I CG +++ YG + SP Y Y +++ C +H+ V + L F +E +S SC + +Y+G N CG + P SSSN + + F+TD ITS+G R
Sbjct: 2553 TGGHFSSPGYDQVNNYTRNLNCEWIIQNPNTENSTTFISFKRLQLE-YHLNCQRDFIELRFDNADGE-------------LITRLCGRNTPSVPLAIVASQ--VWVHFVSNAEVE----------NIGFNASYSFTDCGGIQA-----------------GEY-GVIASPNFPASYNSMSHCAWLLDAPEGHI-ITLSFIHFDI-ESHQICRWDSVTILNGA---SPGSPLIGQFCGTTSPGTIQSGSNKL---LVIF----------NSD---DSLHGRGFYANWT-SDSLG----------------CGGHVHAD---SGTIRSPAWPQHFPANSRCTWT-IETHASSHYELSFNN--NFHIPD-DNGHCQRSYVKVWSGAEE-----ELLATGCGDTAPAPVISPRNVIRVTFQSQD--------------APGSGFFASF-------IS-------KCGANF----TNSSGRIMSPNYPNKYGNNLRCNYTIHAEANMFIVLFFQNFE--------VECKSKTSLSCSKDGLKIF-------GGERTSPLANLCGASVPASISARGS---MSLNFYTDSDINMHGFMATYRVIP--------CGGTFNAS--YGTLRSPTYAFTDYHNNMNCTYHV-TVQENKIIELKFNELDLEASS-SCLYDYIAVYDGLNSSSPLLGRYCG-NVLPPILRSSSNNLFLLFVTDNHITSRGWRA 3115 HSP 10 Score: 73.9442 bits (180), Expect = 1.328e-12 Identity = 132/566 (23.32%), Postives = 211/566 (37.28%), Query Frame = 3
Query: 681 TGEISSPTYPGL--LPSTLNCIYEFRSESTLARI-RLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAV-LRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVI 2363
TG P PG L+C++ ++E RI + F +F+L +Q C EF+++ + DS S+ + CG + SSHN L+ H+ + + GF+I + +RQ EC ++ ++ G I+SPG + C + +T + F L+L + ++ C YL I ++ +Y + + P Q Y++ L+F E +GF ++Y T S C + E G I+SP + Y N C Y +NE I L F + L SY +V + YC T+IP + S +L + FKS+A F A YQ CG ++ G IH+PHYP Y + CEW + P+ + LTF SF I + SN V +R + + CG + +P+ S+ + +RF TD +S GF I + +I
Sbjct: 466 TGSFGYPNNPGTDQHGHMLSCMWVIKTEPRKVRILHITFTNFHL-EQSTPCSTEFLQVHDG---DSISSFMLGKYCGTGVPQEISSSHNSLFFWF------------HSDHISSAG----GFRISWE------------SRQ-----PECGGELM---ETHGSIMSPGYPGNYPPNRDCYWTI----STNPGLYITFAFGTLSLEDHEN--CGKDYLEIRDGLLPQDRVLGKYCSTLSP-APLQT-----SGPYAW----------LHFHSDSTGEDRGFHITYI---------TSPSDPGCGGNFTDNE----GFISSPRWPQPYTGNKQCIYIIQQPANEKISLRFTNLELENSSGCSL-SYMEVRI---------------------------YCNTTIPPPISSSSNAL--WIKFKSDASVTRSSFKAFYQV---------ACGGFLTGA---GVIHTPHYPDAYFRERTCEWII--TQPEGEVVSLTFNSFDILAGTNCGSNFVEIRDGSSSDSPLIGKYCGPEMPVPAQ-STQRALYIRFTTD-SSATNHGFSISYQSLI 910 HSP 11 Score: 73.559 bits (179), Expect = 1.755e-12 Identity = 65/217 (29.95%), Postives = 91/217 (41.94%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYT---GEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEI 845
T G + SP +P YP ++ + + L F+ FN+E +SC DYLDIY + E +GRFCG S IP +I S+ N + + +D NT GF A +Y + + ++C + SYT G SSP YP P+ L CIY E T +I L+F F L C + VEI
Sbjct: 920 TQGTITSPGYPAVYPHGIQCTWFISIPPGNLIRLTFDSFNLE-HGYSCSYDYLDIYDSASA-----------IMESRIGRFCGRS---IPPSITSRGNTMTVLLVTDTNTAVE----------GFSA-----------RYTSLNATTAC------DASYTEASGIFSSPNYPNRYPNNLECIYTITVE-TNKQILLNFTTFVL-STSTNCDKDHVEI 1092 HSP 12 Score: 66.6254 bits (161), Expect = 2.220e-10 Identity = 62/221 (28.05%), Postives = 92/221 (41.63%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLAR-IRLDFIDFNLYQQDEMCPVEFVEIINQPQLDS 869
G L SP WP YP + V N + L F F+IE S S D+L++ S + P++G++CG D +P I SKNNV+ L F SD + G++ W SS ++ L +GS+T SP+YPG + NC E+ + L R I L+F N+ C ++++ N P S
Sbjct: 3373 GYLKSPGWPENYPHNAECTTVLRAPPNHTISLFFNSFSIEATSSSICYDFLEVRNGSDS------------NSPLIGKYCG---DTLPDPIFSKNNVLRLFFKSDL----------VLSSRGYEIT------------WTSSPNACGGTLFGDHGSFT----SPSYPGSYSNNTNC--EWTILAPLGRLITLNFAVLNI-DDSGSCDSNYLKVYNGPDASS 3549 HSP 13 Score: 55.0694 bits (131), Expect = 7.282e-7 Identity = 60/213 (28.17%), Postives = 86/213 (40.38%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGT 2249
G + SP + YP N+ C A N I L F F S S D+L V R + +YCG ++P + S+ L L FKS+ L+S + + CG + +G SP YPG YS++ CEW + ++P R I L F I+ S SC + L++Y G + S L GT
Sbjct: 3373 GYLKSPGWPENYPHNAECTTVLRAPPNHTISLFFNSF-----------SIEATSSSICYDFLEV-----RNGSDSNSPLIGKYCGDTLPDPIFSKNNVL--RLFFKSDL------VLSSRGYEITWTSSPNACGGTLFGD--HGSFTSPSYPGSYSNNTNCEWTI--LAPLGRLITLNFAVLNID-DSGSCDSNYLKVYNGPDAS--SALAGT 3554
BLAST of Cubilin vs. Ensembl Xenopus
Match: wdr81 (WD repeat domain 81 [Source:Xenbase;Acc:XB-GENE-6258221]) HSP 1 Score: 104.375 bits (259), Expect = 7.942e-22 Identity = 181/772 (23.45%), Postives = 289/772 (37.44%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPV-EFVEIINQPQLDS---DSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFT---YLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLS--CHQDYLTVAEIVKRENGFLQTNKTER----YCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF-NVKP-QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNG----------SCPGFQCLNSGHCISKNLTCNKVF 2453
L SP WP Y + +V + + V LN +IE SC D L I R +N + P L CG +P I S + + + F +D + + GF A S+H SC +HAN G I+SP YP + LNC + F S F + D C +++E+ N P S ++ + + CG ++ N +++ V +S + GF++K YE L+ I I SD S G++ SP C + I N E V+L F Y+ E C YL + + K L+ + LCG N L +Y S + L+ F + GFK Y+ + + G H+ G G+I SP Y YP NS C++ F + + + F D+H S C +D++ + E N + R +C + +P LV+ S + + F S+ +NG GF Y +++CG + +++S G I SP+YP Y + +CEW + V R LT + ++ ++C + +Y G+ N P +LCG + SS N +RV F+TD S + GF + + + G S PG+ +N+ ++NL C +
Sbjct: 1977 LFSPGWPNNYASYLDCTWV-IKAPGSTVELNILSVDIEKHR-SCNYDKLVI---------RDGDNN---NSPQLAVVCGKG---VPGPIRSSGDSMFIRFSTDGS----------VSGTGFNA----------------SYHKSCGGYLHAN---RGLITSPNYPEHYSANLNCTWHFLVTSGFTIAAHFEPTFEIPNSDSTCGTGDYLELKNGPDDSSPPMGTSTRNGKFCGTSAPSTMHTTDNEMFVHFVS----------------DNSNEGKGFQLK------YEALSLACGGS---------IYISESDPS-GFVTSPKYPENYPMNADCVW----IITVPNGEAVELEFKEQFYIEPSE----NCSSNYLELRDGADASKRLLAK-------------LCG-NALPITYKSLGTAMYLR--FMTDSGTPRVGFKAMYK----------IATCGGTHF-------GQSGIIQSPGYPLQNYPDNSLCEWYFTGPTGHYLTIQFEAM--------------DLHNSTDCSRDFVEIREY----------NASGRILGVFCNSMVPSDLVTSD-SFAY-IKFVSDQSENGRGFRIRYD------ASTEECGGDYTASS--GIISSPNYPNLYPHNRVCEWRI-TVPAGRRVTLTINALLLQ-DQQNCDYDYVAVYNGYQNQSPLLRKLCGNVAPETEVKSSGNTMRVIFVTD-GSVSSGGFLATFNSMEDAVCGGALADPTGGHFSSPGYDQVNN---YTRNLNCEWII 2589 HSP 2 Score: 100.138 bits (248), Expect = 1.490e-20 Identity = 167/739 (22.60%), Postives = 274/739 (37.08%), Query Frame = 3
Query: 147 IANSSIENIFYEHFYSNKMTGGI-------LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQL--NFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSP--HYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKS-CSNAVLRIYEGFNVKP--QSELCGTDSAIPSYFSSSNFIRVRFLTD 2312
++N+ +ENI + YS GGI + SPN+P Y ++ E + L+F HF+IE C D + I ++ P++G+FCG + P I S +N +++ F N DD + GF AN++ S C +HA+ +G I SP +P P+ C + + ++ + L F + F++ + C +V++ + + L ++ P N+ I+ TF + P + + I ++C S G I+SP CNY IH NM +V NF + C L I+ + T P LCG + + S ++R + LNF GF +YR + GT + G + SP Y Y +N +C Y + N++I L F + SC DY+ V + + + L RYCG +P IL S +L L F ++ H G+ A++ R+ G T+ G SP + GRY S+L C WH+ ++P I LTF++F +E S+S C +++++G Q CG+ P + S+SN + V F++D
Sbjct: 2656 VSNAEVENIGFNASYSFTDCGGIQAGEYGVIASPNFPASYNSMSHCAWLLDAPEGHIITLSFIHFDIESHQI-CRWDSVTI------------LNGASPGSPLIGQFCGTT---SPGTIQSGSNKLLVIF----------NSDDSLHGRGFYANWT-------------SDSLGCGGHVHAD---SGTIRSPAWPQHFPANSRCTWTIETHAS-SHYELSFNNNFHIPDDNGHCQRSYVKV-------------------------WSGAEEELLATGCGDTAPAPVISPRNV-------------IRVTFQSQDAPGSGFF--ASFI--SKCGANFT---NSSGRIMSPNYPNKYGNNLRCNYT---IHAEANMFIVLFFQNFE-VECKSKTSLSCSKDGLKIFGG---------------ERTSPLANLCGAS-VPASISARGS---MSLNFYTDSDINMHGFMATYRVIP---CGGTFNAS--------------YGTLRSPTYAFTDYHNNMNCTYHVTVQENKIIELKFNELDL------------EASSSCLYDYIAVYDGLNSSSPLLG-----RYCGNVLPPILRSSSNNL--FLLFVTDNHITSRGWRATF-----RQTLGPMQGCGGYLTNAAGTFGSPDSNLDGRYDSNLNCAWHI--IAPINTQINLTFSAFFLEAQSRSTCRYDYVKVFDGSTTDSNLQGTYCGSSRPAP-FLSTSNVLTVLFVSD 3239 HSP 3 Score: 96.2857 bits (238), Expect = 2.316e-19 Identity = 160/725 (22.07%), Postives = 277/725 (38.21%), Query Frame = 3
Query: 207 GGILLSPNWPGKYPQDVRYVYVFMGSEN-EQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNA-VLRIYEGFNVKP--------QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQI 2345
G + SP +P YP + +++ E V L+F IE + +C DY++I ++ +N PV GR+CG + IPH I S +N +++ F S+ +T GF A F+ + S+C +H TG +SP+YP P+ C++ S S R+ L F Q + C +++EI + +++ R CG + N + H L+++ V SL GF+ F+ H+ G + G I SP R P NY + N + +++Q +++ + C L IY ++I Y + T P + + + +TS N + +GF L + + F + ++ G C ++ +T + SP + N Y S C + A + + I V D+ + H SC+ D L + R+ + + CG +PG + S S+ + F ++ +G GF ASY CG + + G I SP+YP YS++L C WH S +F+I + +C L + G + + CGT SA + ++ N + V F++D +++G +GFQ+
Sbjct: 1617 GATISSPLYPANYPNNQNCMWIIQAQEPYNHVTLSFTDLEIEFRNDNCTLDYVEI----------LDGNNP--DAPVQGRYCGRT---IPHPITSFSNALVVKFISNNSTS----------AKGFHATFA-------------ASTSACGGTLHME---TGAFNSPSYPENYPANTECVWNILS-SPGNRLLLTFS----VQHSDSCSHDYLEI----REGNETGSLMGRFCGDILPSNITTITGH-ILWIKFVS----------------DGSLSGSGFQATFS----------------HLFG-------NNIGGDRGQIASPLWPRN--YPHYSNYLWK--INVDSSQIIQARILEIDIEDHS--GCIYDKLKIYDGPDTHYHVIGTYCGI---TPPPDIFSSGSSMTVQFTSDNSI-------------NMKGFLLEWLAVDAFSENFPTIAPGACGGILRTGDTPL--FLFSPGWPNNYASYLDCTWVIKAPGSTVELNILSV-----DI--------EKHRSCNYDKLVI-----RDGDNNNSPQLAVVCGKGVPGPIRSSGDSM--FIRFSTDGSVSGTGFNASYH---------KSCGGYLHANR--GLITSPNYPEHYSANLNCTWHFLVTSGFTIAAHFEPTFEIPNSDSTCGTGDYLELKNGPDDSSPPMGTSTRNGKFCGT-SAPSTMHTTDNEMFVHFVSDNSNEG-KGFQL 2194 HSP 4 Score: 92.8189 bits (229), Expect = 2.652e-18 Identity = 164/725 (22.62%), Postives = 284/725 (39.17%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIV-SKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEM--CPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSK---SCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIP 2366
GI+ SPN+P YP + + +V L ++ +C+ DY+ +Y Y+N+ P+L + CG + P V S N + + F +D + + GF A F N M + L G G SSP Y + T N E+ ++ FI F Q + C +F+E+ + D+ + RLCG N + L ++A + ++ N ++ +NIGF ++F+D C IQ+ + G I SP + + C + + ++ L+F + ++ + C+ ++I + + LI ++ T P + G N L + S + + +GF ++ S ++ G H G I SP + +P+NS C + ++ L F + +P D + C + Y+ V + E L T CG + P ++S + + +TF+S G GF AS FI K CG+N +++S G I SP+YP +Y ++L C + +HA + +L F +F++E SK SCS L+I+ G P + LCG +++P+ S+ + + F TD + GF + RVIP
Sbjct: 2447 GIISSPNYPNLYPHNRVCEWRITVPAGRRVTLTINALLLQDQQ-NCDYDYVAVY---NGYQNQ---------SPLLRKLCG---NVAPETEVKSSGNTMRVIFVTDGS----------VSSGGFLATF----NSMEDAVCGGA-------LADPTG---GHFSSPGYDQVNNYTRNLNCEWIIQNPNTENSTTFISFKRLQLEYHLNCQRDFIEL----RFDNADGELITRLCG----------RNTPSVPLAIVASQVWVHFVSNAEV-----ENIGFNASYSFTD-------------------CG-GIQAGEY--GVIASPNFPASYNSMSHCAWLL----DAPEGHIITLSFIHFDIESHQ--ICRWDSVTILNGASPGSPLIGQF---CGTTSPGTIQSGSNKLLVIFNSDDSL-------------HGRGFYANW-------TSDSLGCGGHVHAD--------SGTIRSPAWPQHFPANSRCTWTIETHASSHYEL---SFNNNFHIP-------DDNGHCQRSYVKVWSGAEEE--LLATG-----CGDTAPAPVISPRNVI--RVTFQSQ-DAPGSGFFAS--FISK-------CGANFTNSS--GRIMSPNYPNKYGNNLRCNYTIHAEA-NMFIVLFFQNFEVECKSKTSLSCSKDGLKIFGGERTSPLANLCG--ASVPASISARGSMSLNFYTD-SDINMHGFMATY-RVIP 3017 HSP 5 Score: 85.1149 bits (209), Expect = 5.522e-16 Identity = 163/724 (22.51%), Postives = 262/724 (36.19%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIE---GLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYT---GEISSPTYPGL-LPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G ++SPN+P KY ++R Y N + L F++F +E S SC KD L I+ ++ L CG S +P +I ++ + + L+F++D + GF A + +I G++ G + SPTY + +NC Y + I L F + +L + C +++ + + L+S S+ R CG SS N L+L V + + + G++ TF P+ + GT S D + +N C + + NTQ + L F+ L C+ Y+ ++ S L Y ++P L N L + S + V E+QGF SY KD C Y + T +SP + N YP +SC + A E ++L F+ D C Q+Y+ + + + RYCGT GI + FKS + G GF+ +YQ + ++ +GY+ SP +P Y + C L A P L F SF IE TS S L + G + + CG D+ FS +N +R+ F +D+ +RG++I WT
Sbjct: 2912 GRIMSPNYPNKYGNNLRCNYTIHAEANMFIVLFFQNFEVECKSKTSLSCSKDGLKIFGGERTSP--------------LANLCGAS---VPASISARGS-MSLNFYTDSDINMH----------GFMATYR---------------------VIPCGGTFNASYGTLRSPTYAFTDYHNNMNCTYHVTVQEN-KIIELKFNELDL-EASSSCLYDYIAVYDG--LNS-SSPLLGRYCGNVLPPILRSSSNNLFLLFVT----------------DNHITSRGWRA--TFRQTLGPMQGCGGYLTNAAGT-----FGSPDSNLDGRYDSNLN--------CAWHIIAPINTQ----INLTFSAFFLEAQSRSTCRYDYVKVFDGSTTDSNLQGTY---CGSSRPAPFLSTSNVLTVLFVSDSSV-------------ERQGFNASY-VTKDL----------LCGGSYNATST--SVTTSSPNFPNLYPPFTSCMWIIDAPVKEHVKLSVQSFRLQTDG------------DCSQNYIELKD----------SPVVHRYCGTETFGIPDFYSYGQTAVVVFKSQNYMQGNGFIFTYQTANCSREYNQT----------FGYLKSPGWPENYPHNAECTTVLRA-PPNHTISLFFNSFSIEATSSSICYDFLEVRNGSDSNSPLIGKYCG-DTLPDPIFSKNNVLRLFFKSDLVLS-SRGYEITWT 3482 HSP 6 Score: 82.4185 bits (202), Expect = 3.765e-15 Identity = 170/780 (21.79%), Postives = 274/780 (35.13%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYT---GEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRL--------------------VVLAGRNYMMEPHNIDLYKSSLQNIGFKIK----FTFSDKYEPLNALYNRQDHIPGTEC-----------------------------------DIKIQSSD------------QSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIY-SVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD 2312
T G ++SP +PG YP + + + + F ++E +C KDYL+I +L + VLG++C P + + L F SD + GF Y S C G++T G ISSP +P CIY + + +I L F + L + C + ++EI + D+++ R C SS N L+++ L G + PH D Y F+ + + E ++ +N D + GT C +++ +S+D ++G I SPG C +F + +++L F NL + C YL IY S S M+ I R+ CG++ + S TSR + + L +GF Y L + C Y T G+ +SP Y N YP+N C Y ++N+ I L F F S +C +D++ + R+ G+ + ++C P ++VS L + F+S++ + GF A + + CG ++S S G SP++P Y + C W + A S F + F F +E S C N L +Y+G +LCG P S SN + V+F TD
Sbjct: 591 THGSIMSPGYPGNYPPNRDCYWTISTNPGLYITFAFGTLSLEDHE-NCGKDYLEIR------------DGLLPQDRVLGKYCS---TLSPAPLQTSGPYAWLHFHSDSTGE----------DRGFH-----------ITYITSPSDPGC------GGNFTDNEGFISSPRWPQPYTGNKQCIYIIQQPAN-EKISLRFTNLEL-ENSSGCSLSYMEIRDG---DTETAPLIGRYCNTTIPPPISSSSNALWIKFKSDASVTRSSFKAFYQVACGGFLTGAGVIHTPHYPDAY--------FRERTCEWIITQPEGEVVSLTFNSFDILAGTNCGSNFVEVIFTSYTHLKYCKPTIFVFRLFTFALLFAELQGKSTDCCFFTGCGGTLTDTQGTITSPGYPAVYPHGIQCTWFI----SIPPGNLIRLTFDSFNL--EHGYSCSYDYLDIYDSASAIMESRIGRF-------------CGRS-IPPSITSRGNTMTVLL--VTDTNTAVEGFSARYTSLN---------ATTACDASY----TEASGIFSSPNYPNRYPNNLECIYTITVETNKQILLNFTTFVLSTST------------NCDKDHVEI-----RDGGYEISPLLGKFC-QGPPPVIVSHSNKL--WVKFRSDSSYSETGFSAHWDSA------TTGCGGTLTSVS--GGFTSPNFPMPYYHNSECYWQMMASS-GSTFEIQFEHFDLESHSN-CQNDYLAVYDGNTTHSHLLEKLCGKRLPDPIRSSGSN-VYVKFRTD 1248 HSP 7 Score: 78.5666 bits (192), Expect = 5.220e-14 Identity = 80/281 (28.47%), Postives = 111/281 (39.50%), Query Frame = 3
Query: 24 IAGGLCSEN---ENFQFLIHLNYMIMLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKM-TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYT---GEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEI 845
+AG C N F HL Y I R LF L ++ S + F+ T G + SP +P YP ++ + + L F+ FN+E +SC DYLDIY + E +GRFCG S IP +I S+ N + + +D NT GF A +Y + + ++C + SYT G SSP YP P+ L CIY E T +I L+F F L C + VEI
Sbjct: 862 LAGTNCGSNFVEVIFTSYTHLKYCKPTIFVFR--LFTFALLFAELQGKSTDCCFFTGCGGTLTDTQGTITSPGYPAVYPHGIQCTWFISIPPGNLIRLTFDSFNLE-HGYSCSYDYLDIYDSASA-----------IMESRIGRFCGRS---IPPSITSRGNTMTVLLVTDTNTAVE----------GFSA-----------RYTSLNATTAC------DASYTEASGIFSSPNYPNRYPNNLECIYTITVE-TNKQILLNFTTFVL-STSTNCDKDHVEI 1096 HSP 8 Score: 78.1814 bits (191), Expect = 7.017e-14 Identity = 169/771 (21.92%), Postives = 274/771 (35.54%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAI---PSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV------IPRLSNGSCPGF 2396
L ++F S I + +Y + +++G G SP +P +YP + ++ S + + FNIE S +C D L+IY P L + C P + S N + + F +D ++ GF + E+ C + A GEI SP YP C + R + R+ L F DF++ + C + V + S +D LCG + S+ N +++RL S Q+ GF KFT E +L + S G IS + A+ P N ++ I + V L+FT L + E ++ C Y+ I + + RY CG+ + + TS + +++K F +GF ++ + T G H G NSP Y YP+N+ C ++ + + L F V Q S+ SC DYL + E E G L R+CG +P + + + + F S+ +G GF A++ + + D+ G I SP +P Y W ++ V + IE S C L+IY+G + + GT I P FSS + + V+F +D S +GF + W V P ++ G+C G
Sbjct: 1355 LHVVFHSDDTITRPGFQMQWYVNGCGEELSGPFGSFTSPGFPMRYPDNRECIWHIQTSPGSSIQITIWEFNIEYHS-TCSYDVLEIY------------GGPGVSSPRLAQLCAPRPQENPLQVSSTGNTMTVRFKTDA----------YVSGRGFNT----TWREI---------PGGCGGVFQAP---NGEIHSPNYPRPYEDNTECSWVIRVDFG-HRVLLTFRDFDI-ESHSSCSFDSVTV-------STYSDPLAVLCGTQLPAAISSTQNTMFVRL----------------RSDGSNQHRGFSAKFT-----EACGSLI-----------------TADSIGATISSPLYPANY-PNNQNCMWI-IQAQEPYNHVTLSFTDLEI-EFRNDNCTLDYVEILDGNNPDAPVQGRY-------------CGRT-IPHPITSFSNALVVK--FISNNSTSAKGFHATF-------AASTSACGGTLHME--------TGAFNSPSYPENYPANTECVWNILSSPGNRLLLTFSV-QHSD--------------SCSHDYLEIRE--GNETGSLM----GRFCGDILPSNITTITGHI-LWIKFVSDGSLSGSGFQATFSHLFGNNIGGDR-----------GQIASPLWPRNYPHYSNYLWKIN-VDSSQIIQARILEIDIEDHS-GCIYDKLKIYDGPDT--HYHVIGTYCGITPPPDIFSSGSSMTVQFTSD-NSINMKGFLLEWLAVDAFSENFPTIAPGACGGI 1967 HSP 9 Score: 76.6406 bits (187), Expect = 2.087e-13 Identity = 99/390 (25.38%), Postives = 150/390 (38.46%), Query Frame = 3
Query: 1257 QLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVS-RGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGT-DSAIPSYFSSS-NFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG-FQCLN 2408
++ F + +L + CQ+ YL++Y + +L+++ LCGK P+R + +R SG + + C + + RG++ S Y N YP N C + A I F F + + SC+ DY+ + + ++ + T YCG +P + SL + F S+ PGF + + + + CG +S +G SP +P RY + C WH+ SP +T F IE S +CS VL IY G V ++LC P SS+ N + VRF TD G RGF W R IP G C G FQ N
Sbjct: 1190 EIQFEHFDLESHSN--CQNDYLAVYDGNTTHSHLLEK-------------LCGKR------------------LPDPIRSSGSNVYVKFRTDNSISFSGFFATYKQTCQGVMIANRS--RGILESLNYPNSYPHNQQCNWTIQATLGNTINYTFTTFNV------------EGYFSCN-DYVQLYDGPDKQARLIGT-----YCGNQLPPSGTTTGTSL--HVVFHSDDTITRPGF--------QMQWYVNGCGEELSGP--FGSFTSPGFPMRYPDNRECIWHIQ-TSPGSSIQITIWEFNIEYHS-TCSYDVLEIYGGPGVSSPRLAQLCAPRPQENPLQVSSTGNTMTVRFKTDAYVSG-RGFNTTW-REIP----GGCGGVFQAPN 1506 HSP 10 Score: 74.7146 bits (182), Expect = 8.138e-13 Identity = 160/720 (22.22%), Postives = 278/720 (38.61%), Query Frame = 3
Query: 204 TGGILLSPNWP--GKYPQDVRYVYVFMG--SENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP-GRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD--ITSKGARG 2336
TGG SP + Y +++ ++ +EN ++F+ +E +C++D++++ + + ++ R CG + +P IV+ + + F S+ + +GF A++SF I G Y G I+SP +P S +C + + I L FI F++ + ++C + V I+N S + + CG S N+L LV+ N D SL GF +T SD C + + G I SP + A C + + H + + E+ N ++P+ + CQ Y+ ++S + E + T +T P V+ +N ++ ++ S++ GF S+ IS +C + T G I SP Y N Y +N C Y A++N I L F F+ + LSC +D L + G +T+ CG S+P + ++ +L F +++ N GF+A+Y+ I CG +++ YG + SP Y Y +++ C +H+ V + L F +E +S SC + +Y+G N CG + P SSSN + + F+TD ITS+G R
Sbjct: 2564 TGGHFSSPGYDQVNNYTRNLNCEWIIQNPNTENSTTFISFKRLQLE-YHLNCQRDFIELRFDNADGE-------------LITRLCGRNTPSVPLAIVASQ--VWVHFVSNAEVE----------NIGFNASYSFTDCGGIQA-----------------GEY-GVIASPNFPASYNSMSHCAWLLDAPEGHI-ITLSFIHFDI-ESHQICRWDSVTILNGA---SPGSPLIGQFCGTTSPGTIQSGSNKL---LVIF----------NSD---DSLHGRGFYANWT-SDSLG----------------CGGHVHAD---SGTIRSPAWPQHFPANSRCTWT-IETHASSHYELSFNN--NFHIPD-DNGHCQRSYVKVWSGAEE-----ELLATGCGDTAPAPVISPRNVIRVTFQSQD--------------APGSGFFASF-------IS-------KCGANF----TNSSGRIMSPNYPNKYGNNLRCNYTIHAEANMFIVLFFQNFE--------VECKSKTSLSCSKDGLKIF-------GGERTSPLANLCGASVPASISARGS---MSLNFYTDSDINMHGFMATYRVIP--------CGGTFNAS--YGTLRSPTYAFTDYHNNMNCTYHV-TVQENKIIELKFNELDLEASS-SCLYDYIAVYDGLNSSSPLLGRYCG-NVLPPILRSSSNNLFLLFVTDNHITSRGWRA 3126 HSP 11 Score: 68.1662 bits (165), Expect = 9.149e-11 Identity = 79/323 (24.46%), Postives = 125/323 (38.70%), Query Frame = 3
Query: 1410 CGKNYLKYSYTS-------RNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYE-GFNVKP-QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
CG N+++ +TS + + + +L + E QG F G GT+ T +G I SP Y YP C + +IRL F F SC DYL + + + ++ R+CG SIP + S+ ++ L +N GF A Y + + S T G SP+YP RY ++L C + + V ++ +L FT+F + TS +C + I + G+ + P + C P S SN + V+F +D +S GF W
Sbjct: 867 CGSNFVEVIFTSYTHLKYCKPTIFVFRLFTFALLFAELQGKSTDCCFFT--GCGGTL--------------TDTQGTITSPGYPAVYPHGIQCTWFISIPPGNLIRLTFDSFNLEHG------------YSCSYDYLDIYDSASA----IMESRIGRFCGRSIPPSITSRGNTMTVLLVTDTNTAVE--GFSARYTSLNATTA------CDASYTEASGIFSSPNYPNRYPNNLECIYTI-TVETNKQILLNFTTFVLS-TSTNCDKDHVEIRDGGYEISPLLGKFC--QGPPPVIVSHSNKLWVKFRSD-SSYSETGFSAHW 1144 HSP 12 Score: 66.6254 bits (161), Expect = 2.297e-10 Identity = 62/221 (28.05%), Postives = 92/221 (41.63%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLAR-IRLDFIDFNLYQQDEMCPVEFVEIINQPQLDS 869
G L SP WP YP + V N + L F F+IE S S D+L++ S + P++G++CG D +P I SKNNV+ L F SD + G++ W SS ++ L +GS+T SP+YPG + NC E+ + L R I L+F N+ C ++++ N P S
Sbjct: 3380 GYLKSPGWPENYPHNAECTTVLRAPPNHTISLFFNSFSIEATSSSICYDFLEVRNGSDS------------NSPLIGKYCG---DTLPDPIFSKNNVLRLFFKSDL----------VLSSRGYEIT------------WTSSPNACGGTLFGDHGSFT----SPSYPGSYSNNTNC--EWTILAPLGRLITLNFAVLNI-DDSGSCDSNYLKVYNGPDASS 3556 HSP 13 Score: 62.3882 bits (150), Expect = 5.179e-9 Identity = 65/249 (26.10%), Postives = 102/249 (40.96%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKP--QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
G + SP + YP N+ C A N I L F F S S D+L V R + +YCG ++P + S+ L L FKS+ L+S + + CG + +G SP YPG YS++ CEW + ++P R I L F I+ S SC + L++Y G + CG S+I S+++ + ++F + + GF++ W
Sbjct: 3380 GYLKSPGWPENYPHNAECTTVLRAPPNHTISLFFNSF-----------SIEATSSSICYDFLEV-----RNGSDSNSPLIGKYCGDTLPDPIFSKNNVL--RLFFKSDL------VLSSRGYEITWTSSPNACGGTLFGD--HGSFTSPSYPGSYSNNTNCEWTI--LAPLGRLITLNFAVLNID-DSGSCDSNYLKVYNGPDASSALAGTFCGMGSSIAPLTSTTHQMFIKFHAEQVAL-PSGFRLTW 3598
BLAST of Cubilin vs. Ensembl Xenopus
Match: cdcp2 (CUB domain containing protein 2 [Source:NCBI gene;Acc:100124830]) HSP 1 Score: 82.0333 bits (201), Expect = 2.040e-15 Identity = 70/246 (28.46%), Postives = 110/246 (44.72%), Query Frame = 3
Query: 1611 RGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSE--LCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
G ++SP + YP+++ C + I+L F F + H C DY+ V ++ G N ++CGTS+P L S L T+ F S+ H GF A+Y+ D CG ++ S G I SP YP Y ++ C W + A +P LTFT FQ+E ++ C+ + +++G + CGT + P SS + + V F +D + G RGF+
Sbjct: 37 EGNLSSPNFPGLYPAHTECCWLIVVSEGSTIQLQFHHFNL------------EYHEDCEYDYVKVYNGASKDEG----NLLGKFCGTSLPPQLTSSWHVL--TVIFHSDKHVGSSGFYATYR--------KDICGGILTGLS--GVITSPDYPDNYPNNAECNWLIRA-APGSTVRLTFTDFQME--NEGCNFDYVAVFDGSGAEENQVRYFCGT-TKPPDIKSSFSELLVVFKSDF-NIGGRGFK 249 HSP 2 Score: 80.8777 bits (198), Expect = 4.062e-15 Identity = 112/455 (24.62%), Postives = 182/455 (40.00%), Query Frame = 3
Query: 1020 LQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIY-SVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSK---SCSNAVLRIY--EGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIP 2366
++ I K F + +E ++A+Y R+ G +C + + EG + SP A C + + +QL F + NL +D C+ Y+ +Y S + L+ ++ CG + +S + +L + F GF +YR KD I G ++ TG G+I SP Y + YP+N+ C + A +RL F FQ + C+ DY+ V + E N+ +CGT+ P + S L + FKS+ + G GF A Y +S +C TS G I SP YP Y +++ C W++H + R + F ++E S C L +Y EG + CG + PS SS N + + TD ++GF + + V+P
Sbjct: 1 MRKIPSKYVFMITVLWE-VDAVYARK----GVKCGGVLSAP---EGNLSSPNFPGLYPAHTECCWLIV----VSEGSTIQLQFHHFNLEYHED--CEYDYVKVYNGASKDEGNLLGKF-------------CGTSLPPQLTSSWH---VLTVIFHSDKHVGSSGFYATYR--KD--ICGGIL-------------TGLSGVITSPDYPDNYPNNAECNWLIRAAPGSTVRLTFTDFQMENE-------------GCNFDYVAVFDGSGAEE-----NQVRYFCGTTKPPDIKSSFSEL--LVVFKSDFNIGGRGFKAYY--------YSGECQDTF--TSVKGNITSPRYPDTYPNNINCHWNIH-LPAGFRIKIFFRDLELEERSSLTDGCDYDHLSVYDGEGEHSPLLGRWCGREIP-PSVMSSKNKLLLVLSTD-RDTASKGFVVSYIGVVP 375 HSP 3 Score: 73.9442 bits (180), Expect = 6.135e-13 Identity = 61/214 (28.50%), Postives = 96/214 (44.86%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIIN 851
G L SPN+PG YP ++ + SE + L F HFN+E CE DY+ +Y + K+ N+ LG+FCG SL P + S +V+ + F SDK H+G GF A + C ++ +G I+SP YP P+ C + R+ + + +RL F DF + ++E C ++V + +
Sbjct: 38 GNLSSPNFPGLYPAHTECCWLIVVSEGSTIQLQFHHFNLE-YHEDCEYDYVKVY--NGASKDEGNL---------LGKFCGTSL---PPQLTSSWHVLTVIFHSDK----------HVGSSGFYATY---------------RKDICGGILTG---LSGVITSPDYPDNYPNNAECNWLIRA-APGSTVRLTFTDFQM--ENEGCNFDYVAVFD 205 HSP 4 Score: 56.6102 bits (135), Expect = 1.936e-7 Identity = 66/292 (22.60%), Postives = 117/292 (40.07%), Query Frame = 3
Query: 99 LAMRWD-LFLMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEM---CPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRL 956
L W L ++F S + +S + + +TG G++ SP++P YP + ++ + V L F F +E + C DY+ ++ + +N++ FCG + P +I S + +++ F SD N +G GFKA Y+ S F S G I+SP YP P+ +NC + + RI++ F D L ++ + C + + + + + + + R CG + SS N+L L L
Sbjct: 113 LTSSWHVLTVIFHSDKHVGSSGFYATYRKDICGGILTGLSGVITSPDYPDNYPNNAECNWLIRAAPGSTVRLTFTDFQME--NEGCNFDYVAVFDGSGAEENQVRY------------FCGTTK---PPDIKSSFSELLVVFKSDFN----------IGGRGFKA------------YYYSGECQDTFT------SVKGNITSPRYPDTYPNNINCHWNIHLPAGF-RIKIFFRDLELEERSSLTDGCDYDHLSVYDG---EGEHSPLLGRWCGREIPPSVMSSKNKLLLVL 355
BLAST of Cubilin vs. Ensembl Xenopus
Match: ank3 (ankyrin 3, node of Ranvier (ankyrin G) [Source:Xenbase;Acc:XB-GENE-989433]) HSP 1 Score: 80.1073 bits (196), Expect = 6.460e-15 Identity = 71/252 (28.17%), Postives = 110/252 (43.65%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQT-NKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP-GRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGF---NVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
TG G I S + N+YP N C + ++ L F + D SC DYL + NG +T + CGT PG L+S + L ++ G GF+A Y + S CG + G I++P++P Y S + C WH+ V+PKE+ + L+F F +E S C L ++ G + + + CG DS + +S N + V+F++D+ S A GF
Sbjct: 38 TGDSGFIASEGFPNYYPPNKRCVWKITVPDGHVVMLTFRLLDMEADP------------SCRYDYLNI------YNGHSETAQRLAHVCGTFRPGALLSTGPHM--MLEMVTDEGTGGRGFIAWYSAGSTQPSESQLCGGKLEKPQ--GSINTPNWPDNNYPSGISCSWHI--VAPKEKVVELSFGKFDVEVDSY-CRYDYLAVFNGGKSDDTRLVGKFCG-DSPPKTVYSDGNEMLVQFVSDL-SVTADGF 262
BLAST of Cubilin vs. Ensembl Xenopus
Match: ENSXETT00000007717.1 (tolloid like 2 [Source:NCBI gene;Acc:105947755]) HSP 1 Score: 80.8777 bits (198), Expect = 7.868e-15 Identity = 174/746 (23.32%), Postives = 282/746 (37.80%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFR-SESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVV-----LAG--RNYMME------PHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYS-VSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVII--LKLNF---TQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYR--YQSEETG-------YRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYG--YIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFN-VKPQ-SELCGTDSAIPSYFSSSNFIRVRFLTD--ITSKGARG 2336
+GG +P +P YP ++ + E++ LNF ++ F + D YIE++ R +LGR CG D +P I+S ++ + ++F S N +GK GF A + I K +G+I SP YP CI++ SE L + L F F + + D C +++E+ + S+ + R CG + S+ N+L+++ V AG N+ E P N + + +G ++ EP L + C I Q G I SPG + K C + + + + L F L E D C+ +L I S +S E K K KP+ + N ++ + S N V K+NF K+ G + + FG G + + +E G G I+SP + + YPS C +D + ++L+F F+ + H C D+L E+ NG ++ R+CG+ P +++ S+ L F S+A GF A Y S +CG + + Y H+ Y CEW + A L F +F+IE S C + +Y+G++ P+ CG+ Y S+ + I +RF TD I KG G
Sbjct: 256 SGGNFSAPGYPLGYPSYTHCIWRISVTPGEKIILNFTAMDL----FKSRLCWYD-YIEIRDGYWR--------KAALLGRLCG---DKLPEPIISSDSKLWIEFRSSSNI---------LGK-GFFAVYEAICGGDIKKD-------------------SGQIQSPNYPDDYRPAKECIWKITVSEGFL--VGLSFQAFEIERHDN-CAYDYLEVRDG---FSEDHALIGRFCGYEKPEDIKSTSNKLWIKFVSDGSINKAGFSANFFKEMDECSRPDNGGCSQRCVNTLG-----SYKCVCEPGFELTADKKQCEAA-CGGFIT---QLNGTITSPGWPKEYPTNKNCVWQVVAPAQYR----ISLQFEVFEL-EGNDV-CKYDFLEIRSGLSSESKLHGK----FCGPEKPEVITSQGNTVRLEFKSDNTVSKRGFKVNFFSDKDECSKDNGG--CQHDCVNTFGSYICQCKNGFILHENGHDCKEAGCEQKLINAEGTISSPNWPDKYPSRKECTWDIAVTAGHRVKLVFTDFEIEQ------------HQECAYDHL---ELYDGPNG--KSAILGRFCGSKEPNPVIASTNSM--FLRFYSDASVQRKGFQAKY---------STECGGRLKAEIQTKDIYSHAQFGDNNYPVQSNCEWVIVA-EDGYGVELIFQTFEIEEES-DCGYDYMEVYDGYDSTAPRLGRYCGSGPPEEMY-SAGDSIMIRFHTDDTINKKGFHG 898 HSP 2 Score: 61.2326 bits (147), Expect = 8.771e-9 Identity = 73/272 (26.84%), Postives = 119/272 (43.75%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDV-PAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVI---PRLSNGSCPGFQCLNS 2411
G ++P Y YPS + C + E I L F T+ D+ ++L C DY+ + + R+ L R CG +P ++S L + F+S+++ G GF A Y+ I CG +I S G I SP+YP Y C W + VS L+F +F+IE +C+ L + +GF+ CG + S+SN + ++F++D + A GF + + + R NG C +C+N+
Sbjct: 258 GNFSAPGYPLGYPSYTHCIWRISVTPGEKIILNF----TAMDLFKSRL---------CWYDYIEIRDGYWRKAALLG-----RLCGDKLPEPIISSDSKL--WIEFRSSSNILGKGFFAVYEAI---------CGGDIKKDS--GQIQSPNYPDDYRPAKECIWKI-TVSEGFLVGLSFQAFEIE-RHDNCAYDYLEVRDGFSEDHALIGRFCGYEKP-EDIKSTSNKLWIKFVSDGSINKA-GFSANFFKEMDECSRPDNGGCSQ-RCVNT 493
BLAST of Cubilin vs. Ensembl Mouse
Match: Cubn (cubilin (intrinsic factor-cobalamin receptor) [Source:MGI Symbol;Acc:MGI:1931256]) HSP 1 Score: 108.997 bits (271), Expect = 2.423e-23 Identity = 187/788 (23.73%), Postives = 294/788 (37.31%), Query Frame = 3
Query: 132 LSITKIANSSIEN-IFYEHFYSNKM--------TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCP--VEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDF------KCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCG-TDSAIPSYFSSS-NFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKN 2432
L +T + +SS+EN F F S K+ + GI+ SP P YP V + + + + L F F +E ++C DYL++Y + + LGR+CG S IP ++ S ++ I L F SD + GF N Y A + S C Y N G +SSP +P P NC+Y + +I L F DF L +D P V+FVEI + +++ CG + S N+L+LR ++L GF + S T C + + G + SP NY H+++ ++ + L E +DF C YL+++ LI + + +T P + K+ +++LKL ++ +GF+++YR D + S G++ S Y N Y + C + A + + F+ F +++C DYL + + +R RYCG +IP + L + F ++ +G + FI CG +S T G SP YP Y + C W++ V+P LT F +E SC L IY G F+ ++LC + SA P SS+ N + +RF TD +S RGF W R +P G C G ++ G S N
Sbjct: 906 LYVTFVKSSSMENRGFMAMFSSEKLECGKVLTESTGIIESPGHPNVYPSGVNCTWHIVVQRGQLIRLVFSSFYLE-FHYNCANDYLEVYDTIA--------------QTSLGRYCGKS---IPPSLTSSSHSIKLIFVSDS----------ALAHEGFSIN-----------YEAINASSVCLYDYTDN---FGRLSSPNFPNNYPHNWNCVYRI-TVGLNQQIALHFTDFAL--EDYFGPKCVDFVEIRDG---GFETSPLIGIYCGSVFPPRIISHSNKLWLRFKS----------------DTALTARGFSAYWDASS-----------------TGCGGNLTT---PTGVLTSP------------NYPMPYYHSSECYWRLEASRGSPFLLEFQDFHLEHHPNCSLDYLAVFDGPSTNSRLINK---LCGDTPPAPIRSSKD-----------IVLLKLR--TDAGQQGRGFEINYRQTCDNVVIVNKTS----------------GILESINYPNPYDKDQRCNWTIQATTGNTVNYTFLEFDVEN------------YVNCSTDYLELYDGPQR---------IGRYCGENIPPPGATTGSKL--IVVFHTDGVDSGEKGFKMHWFIHG-------CGGEMSGT--MGSFSSPGYPNSYPHNKECIWNIR-VAPGNSIQLTIHDFDVE-YHASCKYDTLEIYTGLDFHSPRIAQLCSRSPSANPMQISSTDNELAIRFKTD-SSLNGRGFNASW-RAVP----GGCGGIFQVSRGEIHSPN 1525 HSP 2 Score: 105.916 bits (263), Expect = 2.159e-22 Identity = 174/728 (23.90%), Postives = 292/728 (40.11%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIY-EFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPF--YTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQ--CGSNISSTSYYGYIHSPH-YPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSK--SCSNAVLRIYEGFNVKP--QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV 2360
G++ SPN+P Y + + ++ E + L F F++E +C D + + +N + + P++GR+CG S +P I S +N +++ F N ++ GF A ++ ++ C +H++ G I SP +P P C + ES I D +F + D C FV++ + ++NDA +LA + P I +L NI FT + E + A I + C SS G I+SP + CNY+ + +V L F +L +D G + ++ ++IK + + P +CG L+ T PV+ LNF GFK+SYR GI +G G++NSP YTN YP+N C Y +++ RLI + F E VP+ L C DYL V + N ++CG+++P ++ S SL TL FK+++ + G+ S+ R+ Q CG ++ S ++ H G Y L C W++ ++P+ + + LTF +F +E S C+ ++I +G ++ CG+ P + SS NF+ V+F++DI+ + RGF +T V
Sbjct: 2698 GVISSPNYPNLYSRWTQCSWLLEAPEGHTITLTFSDFSVENHP-TCTSDSVTV-------RNGDSPGS-----PIIGRYCGQS---VPGPIQSGSNQLVVTF----------NTNNQGQSRGFYATWN-------------TNTLGCGGTLHSD---NGTIKSPHWPQTFPENSRCSWTAVTHESKHWEISFD-SNFRIPSSDSQCRNSFVKVW---EGMLETNDA-------------------------LLATSCGNVAPSPI----VTLGNI-----FTAVFQSEEMPAQGFSASFI--SRCGRTFNSS---TGDIVSPNFPKHYDNNMNCNYYI----DVAPQSLVILTFVSFHL---EDRSAVSG-----TCDYDGLHIIKGHNL---SSTPLVTICGSETLR-PLTIDGPVM---LNFYSDAYITDFGFKISYRVANCGGI-----------------YSGTYGVLNSPSFSYTN-YPNNVYCVYSLQVRND---RLILLRFNDFEIVPSNL---------CSHDYLEVFDGPSIGN-----RSIGKFCGSTLPQVIKSTNNSL--TLLFKTDSSQTARGWKVSF-----RETIGPQQGCGGYLTEDS-KSFVSPDHDSDGLYDKGLNCIWYI--IAPENKLVKLTFNAFTLEEPSSPGKCTFDYVQIADGASINSYLGGRFCGSSRPAP-FISSGNFLTVQFVSDISIQ-MRGFNATYTFV 3274 HSP 3 Score: 105.531 bits (262), Expect = 2.272e-22 Identity = 162/718 (22.56%), Postives = 256/718 (35.65%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYT---GEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGT-SKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
G + SP +PG YP V+ + S + F ++E + C KDYL+I H+P+LG+FC SL P + + + F SD T GF + +++ + G+YT GE+ P G + C+Y S+ +I ++F L Q C F+E+ D ++CG + F S N +++RL + A K +F Y+ + + EG I SP A + C + + EVV LNFT + C Y+ I S + + ++ CG N + + N +L + F + E +GF + S + G+ +E TG +I SP + N YPS +C + + ++IRL+F F Y + H +C DYL V + + + RYCG SIP L S S+ L F S++ GF +Y+ I V T +G + SP++P Y + C + + V ++ L FT F +E C + V GF P + P S SN + +RF +D T+ ARGF W
Sbjct: 599 GSITSPGYPGNYPPGRDCVWNLLVSPGSLITFTFGTLSLESHN-DCSKDYLEIR------------DGPFHHDPILGKFC-TSLSTPP--LQTTGPAARIHFHSDSETS----------DKGFHITYLTTPSDL-----------------YCGGNYTDTEGELLLPPLTGPFSHSRQCVY-LISQPQGEQIVINFTHVELESQ-RGCSHTFIEV-------GDHESLLRKICGNETLFPIRSISNNVWIRLRIDA----------------------LVQKASFRADYQ------------------VACGGELRGEGVIRSPFYPNAYAGRRTCRWTI----SQPPREVVLLNFTDFQIGSSS--SCDTDYIEIGPSS-------------VLGSPGNEKFCGTNIPSFITSVYN---VLYVTFVKSSSMENRGFMAMF--------SSEKLECGK----VLTESTG---IIESPGHPNVYPSGVNCTWHIVVQRGQLIRLVFSSF------------YLEFHYNCANDYLEVYDTIAQ-------TSLGRYCGKSIPPSLTSSSHSI--KLIFVSDSALAHEGFSINYEAINASSV------CLYDYTDNFGRLSSPNFPNNYPHNWNCVYRI-TVGLNQQIALHFTDFALEDYFGPKCVDFVEIRDGGFETSPLIGIYCGSVFPPRIISHSNKLWLRFKSD-TALTARGFSAYW 1158 HSP 4 Score: 95.1301 bits (235), Expect = 3.485e-19 Identity = 160/705 (22.70%), Postives = 259/705 (36.74%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDI----YIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSI---PGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRV 2297
G L SPN+P YP + VY N+Q+ L+F F +E DY ++E++ + P++G +CG P I+S +N + L F SD + GF A YW +S L + TG ++SP YP + C + + S + L+F DF+L + C ++++ + + P +S N+LCG SS + + L+L AG+ Q GF+I + RQ CD + +++ G + S + CN+ Q +N+T+L C YL +Y + I RY CG+N T+ + +I++ T V ++GFK+ + F+ G E +G G +SP Y N YP N C ++ I+L F + H SC D L + + + + + C S P + S L + FK+++ NG GF AS++ + CG + G IHSP+YP Y ++ C W + V R +L T F +E T ++ L Y+G + + +CG S SS N + V
Sbjct: 1057 GRLSSPNFPNNYPHNWNCVYRITVGLNQQIALHFTDFALE--------DYFGPKCVDFVEIRDGGFETS--------PLIGIYCG---SVFPPRIISHSNKLWLRFKSDT----------ALTARGFSA------------YWDASSTGCGGNLT----TPTGVLTSPNYPMPYYHSSECYWRLEA-SRGSPFLLEFQDFHL-EHHPNCSLDYLAVFDGPSTNSR---LINKLCGDTPPAPIRSSKDIVLLKLRTDAGQ----------------QGRGFEINY--------------RQ------TCD-NVVIVNKTSGILESINYPNPYDKDQRCNW------TIQATTGNTVNYTFLEFDVENYVNCSTDYLELY----DGPQRIGRY-------------CGENIPPPGATTGSKLIVVF--HTDGVDSGEKGFKMHW-FIHGCG----------------GEMSGTMGSFSSPGYPNSYPHNKECIWNIRVAPGNSIQLTIHDFDV------------EYHASCKYDTLEIYTGLD-----FHSPRIAQLCSRSPSANPMQISSTDNEL--AIRFKTDSSLNGRGFNASWRAVPG------GCGGIFQVSR--GEIHSPNYPNNYRANTECSWIIQ-VEKYHRVLLNITDFDLEAT-----DSCLMTYDGSSSANTRVATVCGRQQPPNSITSSGNSLFV 1599 HSP 5 Score: 83.1889 bits (204), Expect = 1.579e-15 Identity = 167/730 (22.88%), Postives = 258/730 (35.34%), Query Frame = 3
Query: 210 GILLSPNWP-GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYP--GLLPSTLNCI-YEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQV--LCGKNY--LKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYR-----GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G+L SP++ YP +V VY + + L F F I + C DYL+++ + S NR +G+FCG +L P I S NN + L F +D + G+K +F E I YL + S+ SP + GL LNCI Y E+ L ++ + C ++V+I + ++S R CG F SS N L ++ V D+ S+Q GF +TF D P YN T SP ++ C + + Q VQ+ L LP QD S S E++ ++T +QV CG NY L Y+S + +++ F DF + R H+ Y+ + G + SP + Y +N C A N I L F FQ + C D+L V R + +YC +P + SQ L L F S+ G Y+ I CG + G + +P +P Y ++ CEW + V+P R + F + C L ++ G N P CG D+ + + +SSN + +RF + + + GF+I+W+
Sbjct: 3046 GVLNSPSFSYTNYPNNVYCVYSLQVRNDRLILLRFNDFEIVPSNL-CSHDYLEVF-DGPSIGNR-----------SIGKFCGSTL---PQVIKSTNNSLTLLFKTDSSQT----------ARGWKVSF----RETI-----GPQQGCGGYLTEDSKSFV----SPDHDSDGLYDKGLNCIWYIIAPENKLVKLTFNAFTLEEPSSPGKCTFDYVQIADGASINSY---LGGRFCGSSRPAPFISSGNFLTVQFVS-------------DI---SIQMRGFNATYTFVDM--PCGGTYNATSMPQNTS----------------SPQLSNIRRPFSTCTWVIEAPPHQQ----VQITVWKLQLPS------QDCSRS----SLELQ--------DSEQTNGNQVTQFCGANYTTLPVFYSSGSTAVVV--------------------FKSDF-----LNRNSRVHFTYEIADCNREYNQAFGNLKSPGWPQGYANNLDCSIILRAPQNHRISLFFYWFQLEDS------------RQCMNDFLEV-----RNGSSSSSPLLGKYCSNLLPNPIFSQSNEL--YLHFHSDDSDTHHG----YEIIWASS--PTGCGGTLLGNE--GILANPGFPDSYPNNTHCEWTI--VAPSGRPLSVGFPFLSIDSPGGCDQNYLILFNGPDANSPPFGPFCGIDTVVAPFHASSNRVFIRFHAEYATV-SSGFEIMWS 3622 HSP 6 Score: 80.1073 bits (196), Expect = 1.548e-14 Identity = 183/797 (22.96%), Postives = 293/797 (36.76%), Query Frame = 3
Query: 120 FLMFLSITKIANSSIENIFYEHFYSNKMTGGI---LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPV-EFVEIINQPQLDS---DSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQ-SEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFT-YLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFY-TNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF-NVKPQ-SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTR--------VIPRLSNG--SCPGFQCLNSGHCISKNLTC 2441
FL+ ++N ++ I +TG SP WPG Y +++ + + V LN +IE SC D L I K +R++ L CG S +P I S + + F SD + GF A+F SC +HA+ G I+SP YP LNC + +S L I + F F + +D C +++ + N P S + + R CGI F+S N ++++ + +S GFKI++ C I D S+GY+ SP N + P+ + I + +QL F N+ E + C YL + + ++ + LCG + +SR ++ L F GFK Y + GT+ +G G+I S Y T Y +N CQ+ + + F F + P C +D++ + E +G L RYCG SIP + + ++ F ++ GF QF R+V CG ++ + G SP+YP ICEW ++ V + ILTFT+ ++ T +SC+ L ++ G N P+ +LC + + SS N ++V F TD S+ GF +T +P +S G S PG+ + ++NL C
Sbjct: 1956 FLLEWFAVDVSNVTLPTIAPGACGGYMVTGDTPVFFFSPGWPGPYGNGADCIWIIY-APDSTVELNILSMDIEA-QLSCSYDKLII----KDGDSRLSQQ--------LAVLCGRS---VPGPIRSTGEYMYIRFTSDGSVT----------GAGFNASF----------------QKSCGGYLHAD---RGIITSPKYPDNYLPNLNCSWHVLVQSGLT-IAVHFEQPFQIQNRDSSCSQGDYLVLRNGPDNHSPPLGPSGGNGRFCGIYTPSTLFTSDNEMFIQFIS----------------DNSNGGQGFKIRY-----------------EAKSLACGGTIYIHDANSDGYVTSP--NYPANYPQHAECIW--ILEAPSGRSIQLQFEDQFNIEETPN--CSASYLELRDGANSNAPVLSK-------------LCGHTLPRNWVSSRG---LMYLKFHTEGGSGYMGFKAKYSIVS---CGGTV--------------SGDSGVIESVGYPTRLYANNVFCQWHIQGLPGHYLTIRFEDFNL-QSSPG-----------CAKDFVEIWE--NHTSGIL----LGRYCGNSIPSSVDTSSNVA--SIRFVTDGSVTDSGF--RLQFKSSREV----CGGDLHGPT--GTFTSPNYPNPNPHPRICEWTIN-VHEGRQIILTFTNLRLS-TQQSCNTEHLIVFNGIRNNSPRLQKLCSRVNVTNEFKSSGNTMKVIFFTD-GSRPYGGFTASYTSSEDAVCGGTLPSVSGGNFSSPGYNGIRD---YARNLDC 2599 HSP 7 Score: 75.485 bits (184), Expect = 3.356e-13 Identity = 67/261 (25.67%), Postives = 102/261 (39.08%), Query Frame = 3
Query: 1446 RNPVII----LKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF 2216
R P++I + ++F R E GF + Y F GI +TG G+I+SP Y N Y + C + A I L F F H +C D +TV R + RYCG S+PG + S L +TF +N GF A++ + CG + S + G I SPH+P + + C W K I ++F+I + C N+ ++++EG
Sbjct: 2655 RVPLVIPYPQVWIHFVSNERVEYTGFYVEYSFTNCGGI-----------------QTGENGVISSPNYPNLYSRWTQCSWLLEAPEGHTITLTFSDFSVEN------------HPTCTSDSVTV-----RNGDSPGSPIIGRYCGQSVPGPIQSGSNQL--VVTFNTNNQGQSRGFYATW------NTNTLGCGGTLHSDN--GTIKSPHWPQTFPENSRCSWTAVTHESKHWEISFDSNFRIPSSDSQCRNSFVKVWEGM 2871 HSP 8 Score: 60.8474 bits (146), Expect = 9.684e-9 Identity = 71/244 (29.10%), Postives = 111/244 (45.49%), Query Frame = 3
Query: 1629 PFYTNFYPSNSSCQYDFFAKSN-EMIRLIFIVF--QTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKP-QSELCGTDSAIPSYFSS--SNFIRVRFLTDITSKGARGFQ 2342
P Y YP+N +C + A+ I L F F Q+S D C +D++ + + + + +Q RYCGTS+P ++S +L T+ F S++ GF A Y + CG + G +SP YP Y S+ C W++ A SP L+F SFQ+E S +C+ + I EG CG +++P +SS + + VRF++D + G GFQ
Sbjct: 1635 PLYPANYPNNQNCTWIIEAQPPFNHIALSFTHFHLQSSTD--------------CTRDFVEILD-GRDSDAPVQG----RYCGTSLPHPIISFGNAL--TVRFVSDSVYGFDGFHAIY------SASTSACGGTFYTGD--GIFNSPGYPEDYHSNTECVWNI-ASSPGNHLQLSFLSFQLE-NSLNCNKDFVEIREGNATGHLMGRYCG--NSLPGNYSSIEGHNLWVRFVSDGSGTGM-GFQ 1844 HSP 9 Score: 59.6918 bits (143), Expect = 2.196e-8 Identity = 127/551 (23.05%), Postives = 199/551 (36.12%), Query Frame = 3
Query: 699 PTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKV-----FSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGA 2330
P YP P+ NC + ++ I L F F+L Q C +FVEI++ DSD+ R CG S N L +R V + Y + + +Y +S G TF N+ +D+ TEC I S SPG L ++L+ C ++ I + +L+ RY CG N L +Y+S L + F GF+ RF FG + + G+ I +PF+ YP NS+ ++ S+ +I + ++ +LT+ +C D L + + + + T YCGT S+ T F S++ K+G GFL + + V CG + + + SP +PG Y + C W ++A P L S IE SCS L I +G + Q + LCG P S+ ++ +RF +D + GA
Sbjct: 1635 PLYPANYPNNQNCTWIIEAQPPFNHIALSFTHFHL-QSSTDCTRDFVEILD--GRDSDA-PVQGRYCGTSLPHPIISFGNALTVRFV--SDSVYGFDGFHA-IYSASTSACG----GTFYTGDGIFNSPGYPEDYHSNTECVWNIAS---------SPG--------------------------NHLQLSFLSFQLENSLNCNKDFVEIREGN-ATGHLMGRY-------------CG-NSLPGNYSSIE-GHNLWVRFVSDGSGTGMGFQA--RFKNIFGNDNIVGTHGK---------------IATPFWPGNYPLNSNYRWTVNVDSSHIIHGRIL------EMDIELTT------NCFYDSLKIYDGFDIHSRLIGT-----YCGTQRESFSSSRNS---LTFQFSSDSSKSGRGFLLEWFAVDVSNVTLPTIAPGACGGYMVTGDTPVFFFSPGWPGPYGNGADCIWIIYA--PDSTVELNILSMDIE-AQLSCSYDKLIIKDGDSRLSQQLAVLCGRSVPGP-IRSTGEYMYIRFTSDGSVTGA 2082 HSP 10 Score: 55.0694 bits (131), Expect = 6.263e-7 Identity = 52/166 (31.33%), Postives = 73/166 (43.98%), Query Frame = 3
Query: 1857 RYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG-FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
RYCG++ P + S SL F L S K G GF A ++ +CG + T YG I SP YPG Y C W+L VSP TF + +E + CS L I +G F+ P T + P ++ R+ F +D + +GF I +
Sbjct: 547 RYCGSTPPQGVHSSANSLYFHL--YSEYIKRGRGFTARWEAKLP------ECGGIL--TGNYGSITSPGYPGNYPPGRDCVWNL-LVSPGSLITFTFGTLSLE-SHNDCSKDYLEIRDGPFHHDPILGKFCTSLSTPPLQTTGPAARIHFHSD-SETSDKGFHITY 699
BLAST of Cubilin vs. Ensembl Mouse
Match: Cdcp2 (CUB domain containing protein 2 [Source:MGI Symbol;Acc:MGI:3045328]) HSP 1 Score: 82.4185 bits (202), Expect = 1.094e-15 Identity = 77/280 (27.50%), Postives = 118/280 (42.14%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKER---FILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCIS 2426
TG G+++SP Y N YP+N C + A ++L+F+ FQ C DY+ V +G YCG + P VS L + FKS+ + G GF A Y FS +C T+ G SP YPG Y +++ C W + + P R FIL + +++C L ++G + + Q + CG P SS N + + TD ++ G RGF + + V+P + S FQ L S ++
Sbjct: 150 TGLSGVLSSPEYPNNYPNNVECHWLIRASGPAAVKLVFVDFQVEGSD------------ECMYDYVAVLGAPGPAHG-------HHYCGRTRPPTFVSLGHEL--QVVFKSDFNIGGRGFKAHY--------FSGECQEVF--TAVRGNFSSPQYPGAYPNNIRCHWTIR-LPPGYRVKVFILDLGLEEPNSLTRTCDFDHLAAFDGASEEAQLLGKWCG-HHLPPPVTSSRNQVLLLLHTDRSTSG-RGFSVAYIGVVPMNVSCSRTDFQILISAQALA 395 HSP 2 Score: 71.633 bits (174), Expect = 2.543e-12 Identity = 64/243 (26.34%), Postives = 97/243 (39.92%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
G +SP + + YP N+ C + + L F F YHD +C D+L + + G N R+CG P S + ++ F S+ H GF A YQ D CG ++ S G + SP YP Y +++ C W + A P L F FQ+EG S C + + CG P++ S + ++V F +D + G RGF+
Sbjct: 39 GNFSSPNFPSLYPYNTECSWLIVVAEGSSVLLTFHAFD---------LEYHD---TCGFDFLEIYNGASGDKG----NLLGRFCGQVPPPPFTSSWHVM--SVVFHSDKHVASRGFSAGYQ--------KDVCGGVLTGLS--GVLSSPEYPNNYPNNVECHWLIRASGPAA-VKLVFVDFQVEG-SDECMYDYVAVLGAPGPAHGHHYCGRTRP-PTFVSLGHELQVVFKSDF-NIGGRGFK 249 HSP 3 Score: 51.2174 bits (121), Expect = 6.637e-6 Identity = 71/319 (22.26%), Postives = 119/319 (37.30%), Query Frame = 3
Query: 111 WDLF-LMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKAN-FSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLVV---LAGRNYMME-----PHNIDLYKSSLQ 1025
W + ++F S +A+ + + +TG G+L SP +P YP +V ++ S V L F F +EG S C DY+ + +CG + P VS + + + F SD N +G GFKA+ FS + E+ T + G SSP YPG P+ + C + R R+++ +D L + + + + + D S +A + CG SS N++ L L +GR + + P N+ ++ Q
Sbjct: 118 WHVMSVVFHSDKHVASRGFSAGYQKDVCGGVLTGLSGVLSSPEYPNNYPNNVECHWLIRASGPAAVKLVFVDFQVEG-SDECMYDYVAVLGAPGPAHGH--------------HYCGRTR---PPTFVSLGHELQVVFKSDFN----------IGGRGFKAHYFSGECQEVFT-------------------AVRGNFSSPQYPGAYPNNIRCHWTIRLPPGY-RVKVFILDLGLEEPNSL--TRTCDFDHLAAFDGASEEAQLLGKWCGHHLPPPVTSSRNQVLLLLHTDRSTSGRGFSVAYIGVVPMNVSCSRTDFQ 386
BLAST of Cubilin vs. Ensembl Mouse
Match: Pcolce2 (procollagen C-endopeptidase enhancer 2 [Source:MGI Symbol;Acc:MGI:1923727]) HSP 1 Score: 77.7962 bits (190), Expect = 1.754e-14 Identity = 65/244 (26.64%), Postives = 103/244 (42.21%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGR-YSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNV---KPQSELCGTDSAIPSYFSSSNFIRVRFLTDIT 2318
TG G I S + YP NS C + +++ L F D +L C D++ V NG + R+CGT PG LV+ + T+ S+A+ G GF+A+Y CG + S G +P++P R Y + C WH+ ++PK + I L F F +E C + ++ G V K + CG +P S N + ++FL+D++
Sbjct: 37 TGESGFIGSEGFPGMYPPNSKCTWKITVPEGKVVVLNFRFIDLEND-----------NL-CRYDFVDV------YNGHANGQRIGRFCGTFRPGSLVASGNKM--TVQMISDANTAGSGFMATYSAAAPDGKGDRYCGGRLEKPS--GTFKTPNWPDRDYPVGVTCVWHI--IAPKNQLIELKFEKFDVE-RDNYCRYDYVAVFNGGEVNDAKRIGKYCGDSPPVP-IVSERNELLIQFLSDLS 254 HSP 2 Score: 53.9138 bits (128), Expect = 7.613e-7 Identity = 56/253 (22.13%), Postives = 97/253 (38.34%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGL-LPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLV 959
G + S +PG YP + + + E + V LNF ++E + C D++D+Y N + +GRFCG F P ++V+ N + + SD NT S GF A +S + + +G +P +P P + C++ + I L F F++ ++D C ++V + N + NDA + CG S N L ++ +
Sbjct: 41 GFIGSEGFPGMYPPNSKCTWKITVPEGKVVVLNFRFIDLENDNL-CRYDFVDVY-------------NGHANGQRIGRFCG---TFRPGSLVASGNKMTVQMISDANTAGS----------GFMATYSAAAPDGKGDRYCGGRLE----------KPSGTFKTPNWPDRDYPVGVTCVWHIIAPKN-QLIELKFEKFDV-ERDNYCRYDYVAVFN----GGEVNDAKRIGKYCGDSPPVPIVSERNELLIQFL 250
BLAST of Cubilin vs. Ensembl Mouse
Match: Cdcp2 (CUB domain containing protein 2 [Source:MGI Symbol;Acc:MGI:3045328]) HSP 1 Score: 75.485 bits (184), Expect = 1.054e-13 Identity = 69/255 (27.06%), Postives = 108/255 (42.35%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKER---FILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
TG G+++SP Y N YP+N C + A ++L+F+ FQ C DY+ V +G YCG + P VS L + FKS+ + G GF A Y + ++VF T+ G SP YPG Y +++ C W + + P R FIL + +++C L ++G + + Q + CG P SS N + + TD ++ G RGF + +
Sbjct: 150 TGLSGVLSSPEYPNNYPNNVECHWLIRASGPAAVKLVFVDFQVEGSD------------ECMYDYVAVLGAPGPAHG-------HHYCGRTRPPTFVSLGHEL--QVVFKSDFNIGGRGFKAHYFSGECQEVF----------TAVRGNFSSPQYPGAYPNNIRCHWTIR-LPPGYRVKVFILDLGLEEPNSLTRTCDFDHLAAFDGASEEAQLLGKWCG-HHLPPPVTSSRNQVLLLLHTDRSTSG-RGFSVAY 370 HSP 2 Score: 71.2478 bits (173), Expect = 2.753e-12 Identity = 64/243 (26.34%), Postives = 98/243 (40.33%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
G +SP + + YP N+ C + + L F F YHD +C D+L + + G N R+CG P S + ++ F S+ H GF A YQ D CG ++ S G + SP YP Y +++ C W + A P L F FQ+EG S C + + CG + P++ S + ++V F +D + G RGF+
Sbjct: 39 GNFSSPNFPSLYPYNTECSWLIVVAEGSSVLLTFHAFD---------LEYHD---TCGFDFLEIYNGASGDKG----NLLGRFCGQVPPPPFTSSWHVM--SVVFHSDKHVASRGFSAGYQ--------KDVCGGVLTGLS--GVLSSPEYPNNYPNNVECHWLIRASGPAA-VKLVFVDFQVEG-SDECMYDYVAVLGAPGPAHGHHYCGR-TRPPTFVSLGHELQVVFKSDF-NIGGRGFK 249 HSP 3 Score: 51.9878 bits (123), Expect = 2.861e-6 Identity = 65/283 (22.97%), Postives = 106/283 (37.46%), Query Frame = 3
Query: 123 LMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKAN-FSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRL 956
++F S +A+ + + +TG G+L SP +P YP +V ++ S V L F F +EG S C DY+ + +CG + P VS + + + F SD N +G GFKA+ FS + E+ T + G SSP YPG P+ + C + R R+++ +D L + + + + + D S +A + CG SS N++ L L
Sbjct: 123 VVFHSDKHVASRGFSAGYQKDVCGGVLTGLSGVLSSPEYPNNYPNNVECHWLIRASGPAAVKLVFVDFQVEG-SDECMYDYVAVLGAPGPAHGH--------------HYCGRTR---PPTFVSLGHELQVVFKSDFN----------IGGRGFKAHYFSGECQEVFT-------------------AVRGNFSSPQYPGAYPNNIRCHWTIRLPPGY-RVKVFILDLGLEEPNSL--TRTCDFDHLAAFDGASEEAQLLGKWCGHHLPPPVTSSRNQVLLLL 355
BLAST of Cubilin vs. Ensembl Mouse
Match: Nrp2 (neuropilin 2 [Source:MGI Symbol;Acc:MGI:1100492]) HSP 1 Score: 69.707 bits (169), Expect = 1.807e-11 Identity = 91/360 (25.28%), Postives = 151/360 (41.94%), Query Frame = 3
Query: 1509 FKLSYRFLKDFGISGTMVSRGR---CHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFA-KSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGT-----SKSCSNAVLRIYEGF-NVKPQ-SELCGTDSAIPSYF-SSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQC-----LNSGHCISKNLTCNKVFNCGSYV---------NNSGLPTIDRSDE 2510
F L++ FL + SG V + C R S++ GY I SP Y YPS+ +C++ +A + N+ I L F P HD C D++ + R+ + ++CG P ++S L + F S+ + G GF Y+ K S+ C N +S + G I SP +P +Y +L C + + A P+ IL F +F +E C L I++G +V P + CGT + PS SS+ + + F TD+ + GF + + FQC + SG ++ ++ + F+ G + +N P +D + E
Sbjct: 4 FPLTWVFLALY-FSGHEVRSQQDPPCGGRLNSKDAGY---ITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNF--------NPHFEIEKHD----CKYDFIEI-----RDGDSESADLLGKHCGNIAPPTIISSGSVL--YIKFTSDYARQGAGFSLRYEIF---KTGSEDCSKNFTSPN--GTIESPGFPEKYPHNLDCTFTILA-KPRMEIILQFLTFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKT--PSKLRSSTGILSLTFHTDM-AVAKDGFSARYYLI----HQEPPENFQCNVPLGMESGRIANEQISASSTFSDGRWTPQQSRLHGDDNGWTPNLDSNKE 327
BLAST of Cubilin vs. UniProt/SwissProt
Match: sp|O70244|CUBN_RAT (Cubilin OS=Rattus norvegicus OX=10116 GN=Cubn PE=1 SV=2) HSP 1 Score: 114.005 bits (284), Expect = 5.014e-24 Identity = 175/718 (24.37%), Postives = 272/718 (37.88%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFT--YLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQI 2345
T G LL P G + + VY+ ++ EQ+ +NF H +E C YIEV H+ +L + CG+ F I S +N + + D Q K F+A++ M+ G SP YP P C + S+ + L+F DF + C +++EI L S N+ + C S +N LY+ V SS++N GF KF+ SDK E L S G I SPG ++ P+ N + + Q ++++L F+ YL + C + YL IY + + + RY CGK+ + S TS + I KL F +GF ++Y + + C Y Y T G+++SP + N YPSN C Y N+ I L F F + ++ + ++ R+ G+ + YCG+ +P ++S L L FKS+A GF A + S CG N+++ + G + SP+YP Y C W L A S F L F F +E SCS L +++G N + +LCG + P S+ + + ++ TD +G RGF+I
Sbjct: 715 TDGELLLPPLSGPFSHSRQCVYLITQAQGEQIVINFTHVELES-QMGCSH----TYIEVGD------------HDSLLRKICGNETLF---PIRSVSNKVWIRLRIDALVQ----------KASFRADYQVACGGMLRG--------------------EGFFRSPFYPNAYPGRRTCRWTI-SQPQRQVVLLNFTDFQI-GSSASCDTDYIEIGPSSVLGSPGNE---KFCSSNIPSFITSVYNILYVTFV----------------KSSSMENRGFTAKFS-SDKLECGEVL-------------------TASTGIIESPG--HPNVYPRGVNCTWHVV--VQRGQLIRLEFSSFYLEF----HYNCTNDYLEIYDTAAQT--FLGRY-------------CGKS-IPPSLTSNSNSI--KLIFVSDSALAHEGFSINYEAIDASSV---------CLYDY----TDNFGMLSSPNFPNNYPSNWECIYRITVGLNQQIALHFTDFTLEDYFGSQCVDFVEI----------------RDGGYETSPLVGIYCGSVLPPTIISHSNKL--WLKFKSDAALTAKGFSAYWDGS------STGCGGNLTTPT--GVLTSPNYPMPYYHSSECYWRLEA-SHGSPFELEFQDFHLE-HHPSCSLDYLAVFDGPTTNSRLIDKLCGDTTPAP-IRSNKDVVLLKLRTDAGQQG-RGFEI 1272 HSP 2 Score: 106.686 bits (265), Expect = 6.983e-22 Identity = 164/715 (22.94%), Postives = 269/715 (37.62%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLG--FTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
G+L SPN+P YP + +Y N+Q+ L+F F +E S D+++I Y+ P++G +CG L P I+S +N + L F SD + GF A YW S L + TG ++SP YP + C + + S + L+F DF+L + C ++++ + + P +S D +LCG S+ + + L+L AG+ Q GF+I F RQ CD + +++ G + S + CN+ Q +N+T+L C Y+ +Y + + RY CG N T+ + + +L T + ++GFK+ + F G E +G G +SP Y N YP N C ++ I+L F + H SC+ D L + + + + + C S P Q S G + FK+++ NG GF AS++ + CG I + G IHSP+YP Y ++ C W + V R +L T F +E ++ LR+ +G + + +CG S +S N + VRF + +S+ RGF+
Sbjct: 1057 GMLSSPNFPNNYPSNWECIYRITVGLNQQIALHFTDFTLEDYFGSQCVDFVEI--RDGGYET----------SPLVGIYCGSVL---PPTIISHSNKLWLKFKSDA----------ALTAKGFSA------------YWDGSSTGCGGNLT----TPTGVLTSPNYPMPYYHSSECYWRLEA-SHGSPFELEFQDFHL-EHHPSCSLDYLAVFDGPTTNSRLID---KLCGDTTPAPIRSNKDVVLLKLRTDAGQ----------------QGRGFEINF--------------RQ------RCD-NVVIVNKTSGILESINYPNPYDKNQRCNW------TIQATTGNTVNYTFLGFDVESYMNCSTDYVELY----DGPQWMGRY-------------CGNNMPPPGATTGSQLHVLF--HTDGINSGEKGFKMQW-FTHGCG----------------GEMSGTAGSFSSPGYPNSYPHNKECIWNIRVAPGSSIQLTIHDFDV------------EYHTSCNYDSLEIYAGLD-----FNSPRIAQLCSQS-PSANPMQVSSTGNELAIRFKTDSTLNGRGFNASWRAVPG------GCGGIIQLSR--GEIHSPNYPNNYRANTECSWIIQ-VERHHRVLLNITDFDLEA-----PDSCLRLMDGSSSTNARVASVCGRQQPPNSIIASGNSLFVRFRSGSSSQN-RGFR 1613 HSP 3 Score: 87.8113 bits (216), Expect = 4.914e-16 Identity = 168/734 (22.89%), Postives = 260/734 (35.42%), Query Frame = 3
Query: 210 GILLSPNWPG-KYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGIN--RASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG---FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG 2393
G++ S +P Y +V + G + L+FE FN++ S C KD+++I+ S + VLGR+CG+S P ++ + +NV + F +D + S GF+ F S C +H TG +SP YP P C + + RI L F + L Q C E + + N GI+ N +L R+ V + +KSS + K+ F F+D P C + S S G SPG N R C + + N E ++ +L L C L + V LI+++ ++ T P + P + ++F R E GF + Y F GI TG G+I+SP Y N Y + + C + A I L F F + H +C D +TV R + RYCG S+P + S L +TF +N GF A++ + CG S + G I SPH+P + + C W + K I ++F+I + C N+ ++++EG N + CG D A +S N F ++ A+GF + R N S PG
Sbjct: 2345 GVIESIGYPTLPYANNVFCQWFIRGLPGHYLTLSFEDFNLQS-SPGCTKDFVEIWENHTSGR-------------VLGRYCGNS---TPSSVDTSSNVASVKFVTDGSVTAS----------GFRLQFK-------------SSRQVCGGDLHGP---TGTFTSPNYPNPNPHARICEWTITVQEG-RRIVLTFTNLRLSTQPS-CNSEHLIVFN----------------GIRSNSPLL---QKLCSRVNV------------TNEFKSSGNTM--KVVF-FTDGSRPYGGFTASYTSTEDAVCGGFLPSV--SGGNFSSPGYNGIRDYARNLDCEWTL----SNPNRENSSISIYFLELSIESHQDCTFDVLE-FRVGDADGPLIEKFCSLSAPTAPLVI---------------PYPQVWIHFVSNERVEYTGFYIEYSFTDCGGI-----------------RTGDNGVISSPNYPNLYSAWTHCSWLLKAPEGHTITLTFSDFLL------------EAHPTCTSDSVTV-----RNGDSPGSPVIGRYCGQSVPRPIQSGSNQL--IVTFNTNNQGQTRGFYATW------TTNALGCGGTFHSAN--GTIKSPHWPQTFPENSRCSWTVITHESKHWEISFDSNFRIPSSDSQCQNSFVKVWEGRLMINKTLLATSCG-DVAPSPIVTSGNIFTAVFQSE--EMAAQGFSASFISRCGRTFNTS-PG 2929 HSP 4 Score: 84.3445 bits (207), Expect = 5.474e-15 Identity = 153/721 (21.22%), Postives = 252/721 (34.95%), Query Frame = 3
Query: 210 GILLSPNWP-GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCI-YEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNY--LKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
GIL SP++ YP ++ VY + + + F F++ + C D+L+++ + S NR LG+FCG + P + S N+ + L F +D + Q K+ F+ YL N S+ S G L+CI Y E+ L ++ + C ++V+I + ++S + CG + F SS N L + V +++ GF +TF D P YN S+ Q+ SP ++ C + Q VQ+ L LP C YL E++ ++ + + CG NY L Y+S + +++ F V + SY+ C+ Y G + SP + Y +N C A N I L F FQ + C D+L V R G + ++YC +P + SQ L + NG Y+ I CG + G +P +P Y ++ CEW + V+P R + F +S C L ++ G N P LCG ++ I +++SSN + +RF + T++ GF+I+W+
Sbjct: 3046 GILRSPSYSYSNYPNNLYCVYSLHVRSSRVIIIRFNDFDVAPSNL-CAHDFLEVF-DGPSIGNR-----------SLGKFCGSTR---PQTVKSTNSSLTLLFKTDSS------QTARGWKIFFRETIG-------------PQQGCGGYLTEDNQSFVSPDSDSN--GRYDKGLSCIWYIVAPENKLVKLTFNVFTLEGPSSAGSCVYDYVQIADGASINSY---LGGKFCGSRMPAPFISSGNFLTFQFVS----------------DVTVEMRGFNATYTFVDM--PCGGTYN-------------ATSTPQNAS---SPHLSNIGRPYSTCTWVIAAPPQQQ----VQITVWDLQLPSQD---CSQSYL-------ELQDSVQTGGNRVTQ------FCGANYTTLPVFYSSMSTAVVV---FKSGVLNRNSQVQFSYQIAD-------------CNREYNQT----FGNLKSPGWPQNYDNNLDCTIILRAPQNHSISLFFYWFQLEDS------------RQCMNDFLEV-----RNGGSSTSPLLDKYCSNLLPNPVFSQSNELYLHFHSDHSVTNNG------YEIIWTSSAAG--CGGTLLGDE--GIFTNPGFPDSYPNNTHCEWTI--VAPSGRPVSVGFPFLSIDSSGGCDQNYLIVFNGPDANSPPFGPLCGINTGIAPFYASSNRVFIRFHAEYTTR-LSGFEIMWS 3622 HSP 5 Score: 81.2629 bits (199), Expect = 4.457e-14 Identity = 177/761 (23.26%), Postives = 281/761 (36.93%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPV-EFVEIINQPQLDS---DSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFT-YLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNF-YPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF--NVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV--------IPRLSNG--SCPGFQCLNSGHCISKNLTC 2441
+ SP WP +Y +++ + + V LN +IE SC D L VK + ++ P L CG S P I S + + F SD + + GF A+F H SC +HA+ G I+SP YP LNC + ++ L I + F F + +D C +++ + N P S + + R CG+ F+S N ++++ + SS GFKI++ + GT + I +D S+GY+ SP N + P+ + I +QL F N+ + + C YL + + L+ + LCG L +S+ S I LK F GFK Y GT+ +G G+I S Y Y +N CQ+ + L F F + P C +D++ + E +G + RYCG S P + + ++ F ++ GF QF R+V CG ++ + G SP+YP ICEW + V R +LTFT+ ++ T SC++ L ++ G N +LC + + SS N ++V F TD S+ GF +T +P +S G S PG+ + ++NL C
Sbjct: 1991 IFSPGWPREYANGADCIWIIY-APDSTVELNILSLDIEPQQ-SCNYDKL----IVKDGDSDLS--------PELAVLCGVSP---PGPIRSTGEYMYIRFTSDTS----------VAGTGFNASF----------------HKSCGGYLHAD---RGVITSPKYPDTYLPNLNCSWHVLVQTGLT-IAVHFEQPFQIQNRDSFCSQGDYLVLRNGPDNHSPPLGPSGRNGRFCGMYAPSTLFTSGNEMFVQFIS----------------DSSNGGQGFKIRYE------------AKSLACGGT---VYIHDAD-SDGYLTSP--NYPANYPQHAECIW--ILEAPPGRSIQLQFEDQFNIEDTPN--CSVSYLELRDGANSNARLVSK-------------LCGHT-LPHSWVSSRERIYLK--FHTDGGSSYMGFKAKYSIAS---CGGTV--------------SGDSGVIESIGYPTLPYANNVFCQWFIRGLPGHYLTLSFEDFNL-QSSPG-----------CTKDFVEIWE--NHTSGRV----LGRYCGNSTPSSVDTSSNVA--SVKFVTDGSVTASGF--RLQFKSSRQV----CGGDLHGPT--GTFTSPNYPNPNPHARICEWTI-TVQEGRRIVLTFTNLRLS-TQPSCNSEHLIVFNGIRSNSPLLQKLCSRVNVTNEFKSSGNTMKVVFFTD-GSRPYGGFTASYTSTEDAVCGGFLPSVSGGNFSSPGYNGIRD---YARNLDC 2599 HSP 6 Score: 80.4925 bits (197), Expect = 8.545e-14 Identity = 90/330 (27.27%), Postives = 145/330 (43.94%), Query Frame = 3
Query: 1389 TKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSK--SCSNAVLRIYEGFNVKP--QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV 2360
+ P +CG L+ T PV+ LNF GFK+SYR + GI Y S G++ SP Y+ + YP+N C Y +S+ R+I I F + P+ L C D+L V + N L ++CG++ P + S SL TL FK+++ + G+ F ++ CG ++ + GRY L C W++ V+P+ + + LTF F +EG S SC ++I +G ++ + CG+ P + SS NF+ +F++D+T + RGF +T V
Sbjct: 2992 STPLVTICGSETLR-PLTVDGPVL---LNFYSDAYTTDFGFKISYRAITCGGI-----------YNESS------GILRSPSYSYSNYPNNLYCVYSLHVRSS---RVIIIRFNDFDVAPSNL---------CAHDFLEVFDGPSIGNRSLG-----KFCGSTRPQTVKSTNSSL--TLLFKTDSSQTARGWKI---FFRETIGPQQGCGGYLTEDNQSFVSPDSDSNGRYDKGLSCIWYI--VAPENKLVKLTFNVFTLEGPSSAGSCVYDYVQIADGASINSYLGGKFCGSRMPAP-FISSGNFLTFQFVSDVTVE-MRGFNATYTFV 3274 HSP 7 Score: 80.1073 bits (196), Expect = 9.866e-14 Identity = 162/720 (22.50%), Postives = 255/720 (35.42%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNA----LYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
G SP +P YP + + + V LNF F I G S SC+ DY++I S++L P +FC + IP I S N++ + F + M GF A FS S C ++ A+ TG I SP +P + P +NC + + IRL+F F L + C +++EI D+ + R CG S+ N + L V S+L + GF I YE ++A LY+ D+ G + SP + C Y N Q + L+FT L + +C D ++ I +E L+ Y P ++ N L L F +GF +Y G G + + G++ SP Y Y +S C + A L F F H SC DYL V + + + ++ CG + P + S + + L +++A + G GF + F +C + + G + S +YP Y + C W + A + TF F +E + +CS + +Y+G PQ CG + P + S + V F TD + G +GF++ W
Sbjct: 825 GFFRSPFYPNAYPGRRTCRWTISQPQRQVVLLNFTDFQI-GSSASCDTDYIEI-----------GPSSVL-GSPGNEKFCSSN---IPSFITSVYNILYVTFV----------KSSSMENRGFTAKFS-------------SDKLECGEVLTAS---TGIIESPGHPNVYPRGVNCTWHVVVQRG-QLIRLEFSSFYL-EFHYNCTNDYLEI-----YDTAAQTFLGRYCGKSIPPSLTSNSNSIKLIFVS----------------DSALAHEGFSIN------YEAIDASSVCLYDYTDNF----------------GMLSSPNFPNNYPSNWECIYRITVGLNQQ----IALHFTDFTLEDYFGSQCVD-FVEIRDGGYETSPLVGIY---CGSVLPPTIISHSNKLW-------------LKFKSDAALTAKGFS-AYWDGSSTGCGGNLTTP--------------TGVLTSPNYPMPYYHSSECYWRLEASHGSPFELEFQDFHLEH------------HPSCSLDYLAVFDGPTTNSRLI-----DKLCGDTTPAPIRSNKDVV--LLKLRTDAGQQGRGFEIN---------FRQRCDNVVIVNKTSGILESINYPNPYDKNQRCNWTIQATT-GNTVNYTFLGFDVE-SYMNCSTDYVELYDG----PQWMGRYCGNNMPPPGATTGSQ-LHVLFHTDGINSGEKGFKMQW 1386 HSP 8 Score: 78.1814 bits (191), Expect = 3.719e-13 Identity = 163/721 (22.61%), Postives = 251/721 (34.81%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFE-HFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFF--AKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIP-GILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAV-LRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G L SPN+P YPQ +++ + L FE FNIE +C YL++ S + ++ + CGH+L PH+ VS I L F +D + + +GFKA +S +SC + + I PT P + + C + R + L F DFNL Q C +FVEI + S R CG +S N ++ V S+ GF+++F S + + H P G SP + +IC + Q + L FT L L C +L +++ L+++ + + T N K S + +K+ F + GF SY +D G + S ++ GY G+ + Y N C++ + N I + F+ ++ + HQD ++++ G E++C S P LV + + F SN GF Y F CG T G I SP+YP YS+ C W L A P+ I LTF+ F +E S++V +R + CG P S SN + V F T+ + RGF WT
Sbjct: 2230 GYLTSPNYPANYPQHAECIWILEAPPGRSIQLQFEDQFNIEDTP-NCSVSYLELRDGANS------------NARLVSKLCGHTL---PHSWVSSRERIYLKFHTDGGSSY----------MGFKAKYSI---------------ASCGGTVSGDSGVIESIGYPTLP--YANNVFCQWFIRGLPG-HYLTLSFEDFNL-QSSPGCTKDFVEIWE----NHTSGRVLGRYCGNSTPSSVDTSSNVASVKFVT----------------DGSVTASGFRLQFKSSRQ------VCGGDLHGP--------------TGTFTSPNYPNPNPHARICEWTIT----VQEGRRIVLTFTNLRLSTQP--SCNSEHLIVFNGIRSNSPLLQKLCSRVNVT---------NEFKSSGNT------MKVVFFTDGSRPYGGFTASYTSTEDAVCGGFLPSVSGGNF----SSPGYNGIRD-------YARNLDCEWTLSNPNRENSSISIYFL----------------ELSIESHQD--CTFDVLEFRVGDADGPLIEKFCSLSAPTAPLVIPYPQV--WIHFVSNERVEYTGFYIEYSFT--------DCGG--IRTGDNGVISSPNYPNLYSAWTHCSWLLKA--PEGHTITLTFSDFLLEAHPTCTSDSVTVRNGDSPGSPVIGRYCGQSVPRPIQ-SGSNQLIVTFNTNNQGQ-TRGFYATWT 2799 HSP 9 Score: 70.0922 bits (170), Expect = 1.204e-10 Identity = 151/686 (22.01%), Postives = 247/686 (36.01%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYE----HFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEH-FNIEGL-SFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLG------RFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSD---QSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTL--TFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPG--RYSSDLICEWHL 2108
+++ F S T +A + F++ + ++++ G++ SP +P Y ++ + + + ++FE F I+ SF + DYL + R N H P LG RFCG + P + + N + + F SD + G GFK +Y A S IH + G ++SP YP P CI+ + + I+L F D FN+ + C V ++E+ D +++A ++LCG + SS R+YL+ G +YM GFK K++ + C + +S GY P N C +F G+ + L+F NL C ++ I+ + ++ RY CG + TS N + + F GF+L ++ S V G H G G SP Y N P C++ + I L F + S SC+ ++L V ++ + LQ + C + ++ KS G T+ F ++ + GF ASY + CG + S S G SP Y G Y+ +L CEW L
Sbjct: 2069 MYIRFTSDTSVAGTGFNASFHKSCGGYLHADR---GVITSPKYPDTYLPNLNCSWHVLVQTGLTIAVHFEQPFQIQNRDSFCSQGDYLVL---------RNGPDN---HSPPLGPSGRNGRFCGM---YAPSTLFTSGNEMFVQFISDSSN----------GGQGFK-----------IRYEAKSLACGGTVYIH-DADSDGYLTSPNYPANYPQHAECIWILEAPPGRS-IQLQFEDQFNI-EDTPNCSVSYLEL-----RDGANSNARLVSKLCGHTLPHSWVSSRERIYLKFHTDGGSSYM----------------GFKAKYSIA-------------------SCGGTVSGDSGVIESIGYPTLPYANNV-----FCQWFIRGLPG----HYLTLSFEDFNL--QSSPGCTKDFVEIWE-NHTSGRVLGRY-------------CGNSTPSSVDTSSN---VASVKFVTDGSVTASGFRLQFK-------SSRQVCGGDLH--------GPTGTFTSPNYPNPNPHARICEWTITVQEGRRIVLTFTNLRLS------------TQPSCNSEHLIVFNGIRSNSPLLQ-----KLCSRV---NVTNEFKSSGNTMKVVFFTDGSRPYGGFTASYTSTEDAV-----CGGFLPSVS-GGNFSSPGYNGIRDYARNLDCEWTL 2603 HSP 10 Score: 69.707 bits (169), Expect = 1.449e-10 Identity = 167/733 (22.78%), Postives = 269/733 (36.70%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGS----YTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEI-----INQP---QLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKD--FKCQDGYLSIYSVSFEMKYLIKRYRTVI-KETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSN-EMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSS--NFIRVRFLTDITSKGARGFQ 2342
T GIL S N+P Y ++ R + + V+ F F++E +C DY+++Y + +GR+CG+++ P + + + +L F +D + G+ GFK + H G G SSP YP P CI+ R + + I+L DF++ + C + +EI N P QL S S A+ Q S+ N L +R S+L GF + +PG C IQ S G I SP A C++ I + V LN T +L E D + DG S + R +V ++ P+ ++ N L + F + +GF+ +R C R ++ + I SP Y + Y N +C + A+ I L F FQ C +D++ EI+ + RYCG S+P ++S +L T+ F +++ ++ GF A Y + CG + + G +SP YP Y + C W++ A SP R L+F SF +E S +C+ + I EG N CG +++P +SS+ + + VRF++D + G GFQ
Sbjct: 1287 TSGILESINYPNPYDKNQRCNWTIQATTGNTVNYTFLGFDVESY-MNCSTDYVELYDGPQ----------------WMGRYCGNNMP--PPGATTGSQLHVL-FHTDG---------INSGEKGFKMQ----------------------WFTHGCGGEMSGTAGSFSSPGYPNSYPHNKECIWNIRV-APGSSIQLTIHDFDV-EYHTSCNYDSLEIYAGLDFNSPRIAQLCSQSPSANP--------MQVSSTGNELAIRFKT----------------DSTLNGRGFNASWR----------------AVPGG-CGGIIQ---LSRGEIHSPNYPNNYRANTECSW----IIQVERHHRVLLNITDFDL-EAPDSCLRLMDGSSSTNA----------RVASVCGRQQPPNSIIASGNSLF-------------VRFRSGSSSQNRGFRAEFR--------------EECGGRIMTDSSD---TIFSPLYPHNYLHNQNCSWIIEAQPPFNHITLSFTHFQLQNST------------DCTRDFV---EILDGND--YDAPVQGRYCGFSLPHPIISFGNAL--TVRFVTDSTRSFEGFRAIY------SASTSSCGGSFYTLD--GIFNSPDYPADYHPNAECVWNI-ASSPGNRLQLSFLSFNLE-NSLNCNKDFVEIREG-NATGHLIGRYCG--NSLPGNYSSAEGHSLWVRFVSDGSGTGM-GFQ 1844 HSP 11 Score: 60.8474 bits (146), Expect = 6.605e-8 Identity = 81/311 (26.05%), Postives = 121/311 (38.91%), Query Frame = 3
Query: 1485 PVRKEQQGFKLSYRFLKDFGISGTMVSRG-RCHYRYQSEETG-----YRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG 2393
P++ G +L+ RF D ++G RG +R G RG I+SP Y N Y +N+ C + + + + L F + P D S + VA + R+ P +++ SL + F+S + GF R F ++CG I + S I SP YP Y + C W + A P L+FT FQ++ S C+ + I +G ++ Q CG P S N + VRF+TD T + GF R I S SC G
Sbjct: 1474 PMQVSSTGNELAIRFKTDSTLNG----RGFNASWRAVPGGCGGIIQLSRGEIHSPNYPNNYRANTECSWIIQVERHHRVLLNITDFDL--EAPDSCLRLMDGSSSTNA---RVASVCGRQQ---------------PPNSIIASGNSL--FVRFRSGSSSQNRGF---------RAEFREECGGRIMTDSS-DTIFSPLYPHNYLHNQNCSWIIEAQPPFNHITLSFTHFQLQ-NSTDCTRDFVEILDGNDYDAPVQGRYCGFSLPHP-IISFGNALTVRFVTDST-RSFEGF-----RAIYSASTSSCGG 1740
BLAST of Cubilin vs. UniProt/SwissProt
Match: sp|Q9JLB4|CUBN_MOUSE (Cubilin OS=Mus musculus OX=10090 GN=Cubn PE=1 SV=3) HSP 1 Score: 108.997 bits (271), Expect = 1.695e-22 Identity = 187/788 (23.73%), Postives = 294/788 (37.31%), Query Frame = 3
Query: 132 LSITKIANSSIEN-IFYEHFYSNKM--------TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCP--VEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDF------KCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCG-TDSAIPSYFSSS-NFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKN 2432
L +T + +SS+EN F F S K+ + GI+ SP P YP V + + + + L F F +E ++C DYL++Y + + LGR+CG S IP ++ S ++ I L F SD + GF N Y A + S C Y N G +SSP +P P NC+Y + +I L F DF L +D P V+FVEI + +++ CG + S N+L+LR ++L GF + S T C + + G + SP NY H+++ ++ + L E +DF C YL+++ LI + + +T P + K+ +++LKL ++ +GF+++YR D + S G++ S Y N Y + C + A + + F+ F +++C DYL + + +R RYCG +IP + L + F ++ +G + FI CG +S T G SP YP Y + C W++ V+P LT F +E SC L IY G F+ ++LC + SA P SS+ N + +RF TD +S RGF W R +P G C G ++ G S N
Sbjct: 906 LYVTFVKSSSMENRGFMAMFSSEKLECGKVLTESTGIIESPGHPNVYPSGVNCTWHIVVQRGQLIRLVFSSFYLE-FHYNCANDYLEVYDTIA--------------QTSLGRYCGKS---IPPSLTSSSHSIKLIFVSDS----------ALAHEGFSIN-----------YEAINASSVCLYDYTDN---FGRLSSPNFPNNYPHNWNCVYRI-TVGLNQQIALHFTDFAL--EDYFGPKCVDFVEIRDG---GFETSPLIGIYCGSVFPPRIISHSNKLWLRFKS----------------DTALTARGFSAYWDASS-----------------TGCGGNLTT---PTGVLTSP------------NYPMPYYHSSECYWRLEASRGSPFLLEFQDFHLEHHPNCSLDYLAVFDGPSTNSRLINK---LCGDTPPAPIRSSKD-----------IVLLKLR--TDAGQQGRGFEINYRQTCDNVVIVNKTS----------------GILESINYPNPYDKDQRCNWTIQATTGNTVNYTFLEFDVEN------------YVNCSTDYLELYDGPQR---------IGRYCGENIPPPGATTGSKL--IVVFHTDGVDSGEKGFKMHWFIHG-------CGGEMSGT--MGSFSSPGYPNSYPHNKECIWNIR-VAPGNSIQLTIHDFDVE-YHASCKYDTLEIYTGLDFHSPRIAQLCSRSPSANPMQISSTDNELAIRFKTD-SSLNGRGFNASW-RAVP----GGCGGIFQVSRGEIHSPN 1525 HSP 2 Score: 105.916 bits (263), Expect = 1.510e-21 Identity = 174/728 (23.90%), Postives = 292/728 (40.11%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIY-EFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPF--YTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQ--CGSNISSTSYYGYIHSPH-YPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSK--SCSNAVLRIYEGFNVKP--QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV 2360
G++ SPN+P Y + + ++ E + L F F++E +C D + + +N + + P++GR+CG S +P I S +N +++ F N ++ GF A ++ ++ C +H++ G I SP +P P C + ES I D +F + D C FV++ + ++NDA +LA + P I +L NI FT + E + A I + C SS G I+SP + CNY+ + +V L F +L +D G + ++ ++IK + + P +CG L+ T PV+ LNF GFK+SYR GI +G G++NSP YTN YP+N C Y +++ RLI + F E VP+ L C DYL V + N ++CG+++P ++ S SL TL FK+++ + G+ S+ R+ Q CG ++ S ++ H G Y L C W++ ++P+ + + LTF +F +E S C+ ++I +G ++ CG+ P + SS NF+ V+F++DI+ + RGF +T V
Sbjct: 2698 GVISSPNYPNLYSRWTQCSWLLEAPEGHTITLTFSDFSVENHP-TCTSDSVTV-------RNGDSPGS-----PIIGRYCGQS---VPGPIQSGSNQLVVTF----------NTNNQGQSRGFYATWN-------------TNTLGCGGTLHSD---NGTIKSPHWPQTFPENSRCSWTAVTHESKHWEISFD-SNFRIPSSDSQCRNSFVKVW---EGMLETNDA-------------------------LLATSCGNVAPSPI----VTLGNI-----FTAVFQSEEMPAQGFSASFI--SRCGRTFNSS---TGDIVSPNFPKHYDNNMNCNYYI----DVAPQSLVILTFVSFHL---EDRSAVSG-----TCDYDGLHIIKGHNL---SSTPLVTICGSETLR-PLTIDGPVM---LNFYSDAYITDFGFKISYRVANCGGI-----------------YSGTYGVLNSPSFSYTN-YPNNVYCVYSLQVRND---RLILLRFNDFEIVPSNL---------CSHDYLEVFDGPSIGN-----RSIGKFCGSTLPQVIKSTNNSL--TLLFKTDSSQTARGWKVSF-----RETIGPQQGCGGYLTEDS-KSFVSPDHDSDGLYDKGLNCIWYI--IAPENKLVKLTFNAFTLEEPSSPGKCTFDYVQIADGASINSYLGGRFCGSSRPAP-FISSGNFLTVQFVSDISIQ-MRGFNATYTFV 3274 HSP 3 Score: 105.531 bits (262), Expect = 1.589e-21 Identity = 162/718 (22.56%), Postives = 256/718 (35.65%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYT---GEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGT-SKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
G + SP +PG YP V+ + S + F ++E + C KDYL+I H+P+LG+FC SL P + + + F SD T GF + +++ + G+YT GE+ P G + C+Y S+ +I ++F L Q C F+E+ D ++CG + F S N +++RL + A K +F Y+ + + EG I SP A + C + + EVV LNFT + C Y+ I S + + ++ CG N + + N +L + F + E +GF + S + G+ +E TG +I SP + N YPS +C + + ++IRL+F F Y + H +C DYL V + + + RYCG SIP L S S+ L F S++ GF +Y+ I V T +G + SP++P Y + C + + V ++ L FT F +E C + V GF P + P S SN + +RF +D T+ ARGF W
Sbjct: 599 GSITSPGYPGNYPPGRDCVWNLLVSPGSLITFTFGTLSLESHN-DCSKDYLEIR------------DGPFHHDPILGKFC-TSLSTPP--LQTTGPAARIHFHSDSETS----------DKGFHITYLTTPSDL-----------------YCGGNYTDTEGELLLPPLTGPFSHSRQCVY-LISQPQGEQIVINFTHVELESQ-RGCSHTFIEV-------GDHESLLRKICGNETLFPIRSISNNVWIRLRIDA----------------------LVQKASFRADYQ------------------VACGGELRGEGVIRSPFYPNAYAGRRTCRWTI----SQPPREVVLLNFTDFQIGSSS--SCDTDYIEIGPSS-------------VLGSPGNEKFCGTNIPSFITSVYN---VLYVTFVKSSSMENRGFMAMF--------SSEKLECGK----VLTESTG---IIESPGHPNVYPSGVNCTWHIVVQRGQLIRLVFSSF------------YLEFHYNCANDYLEVYDTIAQ-------TSLGRYCGKSIPPSLTSSSHSI--KLIFVSDSALAHEGFSINYEAINASSV------CLYDYTDNFGRLSSPNFPNNYPHNWNCVYRI-TVGLNQQIALHFTDFALEDYFGPKCVDFVEIRDGGFETSPLIGIYCGSVFPPRIISHSNKLWLRFKSD-TALTARGFSAYW 1158 HSP 4 Score: 95.1301 bits (235), Expect = 2.438e-18 Identity = 160/705 (22.70%), Postives = 259/705 (36.74%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDI----YIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSI---PGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRV 2297
G L SPN+P YP + VY N+Q+ L+F F +E DY ++E++ + P++G +CG P I+S +N + L F SD + GF A YW +S L + TG ++SP YP + C + + S + L+F DF+L + C ++++ + + P +S N+LCG SS + + L+L AG+ Q GF+I + RQ CD + +++ G + S + CN+ Q +N+T+L C YL +Y + I RY CG+N T+ + +I++ T V ++GFK+ + F+ G E +G G +SP Y N YP N C ++ I+L F + H SC D L + + + + + C S P + S L + FK+++ NG GF AS++ + CG + G IHSP+YP Y ++ C W + V R +L T F +E T ++ L Y+G + + +CG S SS N + V
Sbjct: 1057 GRLSSPNFPNNYPHNWNCVYRITVGLNQQIALHFTDFALE--------DYFGPKCVDFVEIRDGGFETS--------PLIGIYCG---SVFPPRIISHSNKLWLRFKSDT----------ALTARGFSA------------YWDASSTGCGGNLT----TPTGVLTSPNYPMPYYHSSECYWRLEA-SRGSPFLLEFQDFHL-EHHPNCSLDYLAVFDGPSTNSR---LINKLCGDTPPAPIRSSKDIVLLKLRTDAGQ----------------QGRGFEINY--------------RQ------TCD-NVVIVNKTSGILESINYPNPYDKDQRCNW------TIQATTGNTVNYTFLEFDVENYVNCSTDYLELY----DGPQRIGRY-------------CGENIPPPGATTGSKLIVVF--HTDGVDSGEKGFKMHW-FIHGCG----------------GEMSGTMGSFSSPGYPNSYPHNKECIWNIRVAPGNSIQLTIHDFDV------------EYHASCKYDTLEIYTGLD-----FHSPRIAQLCSRSPSANPMQISSTDNEL--AIRFKTDSSLNGRGFNASWRAVPG------GCGGIFQVSR--GEIHSPNYPNNYRANTECSWIIQ-VEKYHRVLLNITDFDLEAT-----DSCLMTYDGSSSANTRVATVCGRQQPPNSITSSGNSLFV 1599 HSP 5 Score: 83.1889 bits (204), Expect = 1.104e-14 Identity = 167/730 (22.88%), Postives = 258/730 (35.34%), Query Frame = 3
Query: 210 GILLSPNWP-GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYP--GLLPSTLNCI-YEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQV--LCGKNY--LKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYR-----GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G+L SP++ YP +V VY + + L F F I + C DYL+++ + S NR +G+FCG +L P I S NN + L F +D + G+K +F E I YL + S+ SP + GL LNCI Y E+ L ++ + C ++V+I + ++S R CG F SS N L ++ V D+ S+Q GF +TF D P YN T SP ++ C + + Q VQ+ L LP QD S S E++ ++T +QV CG NY L Y+S + +++ F DF + R H+ Y+ + G + SP + Y +N C A N I L F FQ + C D+L V R + +YC +P + SQ L L F S+ G Y+ I CG + G + +P +P Y ++ CEW + V+P R + F + C L ++ G N P CG D+ + + +SSN + +RF + + + GF+I+W+
Sbjct: 3046 GVLNSPSFSYTNYPNNVYCVYSLQVRNDRLILLRFNDFEIVPSNL-CSHDYLEVF-DGPSIGNR-----------SIGKFCGSTL---PQVIKSTNNSLTLLFKTDSSQT----------ARGWKVSF----RETI-----GPQQGCGGYLTEDSKSFV----SPDHDSDGLYDKGLNCIWYIIAPENKLVKLTFNAFTLEEPSSPGKCTFDYVQIADGASINSY---LGGRFCGSSRPAPFISSGNFLTVQFVS-------------DI---SIQMRGFNATYTFVDM--PCGGTYNATSMPQNTS----------------SPQLSNIRRPFSTCTWVIEAPPHQQ----VQITVWKLQLPS------QDCSRS----SLELQ--------DSEQTNGNQVTQFCGANYTTLPVFYSSGSTAVVV--------------------FKSDF-----LNRNSRVHFTYEIADCNREYNQAFGNLKSPGWPQGYANNLDCSIILRAPQNHRISLFFYWFQLEDS------------RQCMNDFLEV-----RNGSSSSSPLLGKYCSNLLPNPIFSQSNEL--YLHFHSDDSDTHHG----YEIIWASS--PTGCGGTLLGNE--GILANPGFPDSYPNNTHCEWTI--VAPSGRPLSVGFPFLSIDSPGGCDQNYLILFNGPDANSPPFGPFCGIDTVVAPFHASSNRVFIRFHAEYATV-SSGFEIMWS 3622 HSP 6 Score: 80.1073 bits (196), Expect = 1.083e-13 Identity = 183/797 (22.96%), Postives = 293/797 (36.76%), Query Frame = 3
Query: 120 FLMFLSITKIANSSIENIFYEHFYSNKMTGGI---LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPV-EFVEIINQPQLDS---DSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQ-SEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFT-YLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFY-TNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF-NVKPQ-SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTR--------VIPRLSNG--SCPGFQCLNSGHCISKNLTC 2441
FL+ ++N ++ I +TG SP WPG Y +++ + + V LN +IE SC D L I K +R++ L CG S +P I S + + F SD + GF A+F SC +HA+ G I+SP YP LNC + +S L I + F F + +D C +++ + N P S + + R CGI F+S N ++++ + +S GFKI++ C I D S+GY+ SP N + P+ + I + +QL F N+ E + C YL + + ++ + LCG + +SR ++ L F GFK Y + GT+ +G G+I S Y T Y +N CQ+ + + F F + P C +D++ + E +G L RYCG SIP + + ++ F ++ GF QF R+V CG ++ + G SP+YP ICEW ++ V + ILTFT+ ++ T +SC+ L ++ G N P+ +LC + + SS N ++V F TD S+ GF +T +P +S G S PG+ + ++NL C
Sbjct: 1956 FLLEWFAVDVSNVTLPTIAPGACGGYMVTGDTPVFFFSPGWPGPYGNGADCIWIIY-APDSTVELNILSMDIEA-QLSCSYDKLII----KDGDSRLSQQ--------LAVLCGRS---VPGPIRSTGEYMYIRFTSDGSVT----------GAGFNASF----------------QKSCGGYLHAD---RGIITSPKYPDNYLPNLNCSWHVLVQSGLT-IAVHFEQPFQIQNRDSSCSQGDYLVLRNGPDNHSPPLGPSGGNGRFCGIYTPSTLFTSDNEMFIQFIS----------------DNSNGGQGFKIRY-----------------EAKSLACGGTIYIHDANSDGYVTSP--NYPANYPQHAECIW--ILEAPSGRSIQLQFEDQFNIEETPN--CSASYLELRDGANSNAPVLSK-------------LCGHTLPRNWVSSRG---LMYLKFHTEGGSGYMGFKAKYSIVS---CGGTV--------------SGDSGVIESVGYPTRLYANNVFCQWHIQGLPGHYLTIRFEDFNL-QSSPG-----------CAKDFVEIWE--NHTSGIL----LGRYCGNSIPSSVDTSSNVA--SIRFVTDGSVTDSGF--RLQFKSSREV----CGGDLHGPT--GTFTSPNYPNPNPHPRICEWTIN-VHEGRQIILTFTNLRLS-TQQSCNTEHLIVFNGIRNNSPRLQKLCSRVNVTNEFKSSGNTMKVIFFTD-GSRPYGGFTASYTSSEDAVCGGTLPSVSGGNFSSPGYNGIRD---YARNLDC 2599 HSP 7 Score: 75.485 bits (184), Expect = 2.348e-12 Identity = 67/261 (25.67%), Postives = 102/261 (39.08%), Query Frame = 3
Query: 1446 RNPVII----LKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF 2216
R P++I + ++F R E GF + Y F GI +TG G+I+SP Y N Y + C + A I L F F H +C D +TV R + RYCG S+PG + S L +TF +N GF A++ + CG + S + G I SPH+P + + C W K I ++F+I + C N+ ++++EG
Sbjct: 2655 RVPLVIPYPQVWIHFVSNERVEYTGFYVEYSFTNCGGI-----------------QTGENGVISSPNYPNLYSRWTQCSWLLEAPEGHTITLTFSDFSVEN------------HPTCTSDSVTV-----RNGDSPGSPIIGRYCGQSVPGPIQSGSNQL--VVTFNTNNQGQSRGFYATW------NTNTLGCGGTLHSDN--GTIKSPHWPQTFPENSRCSWTAVTHESKHWEISFDSNFRIPSSDSQCRNSFVKVWEGM 2871 HSP 8 Score: 60.8474 bits (146), Expect = 6.774e-8 Identity = 71/244 (29.10%), Postives = 111/244 (45.49%), Query Frame = 3
Query: 1629 PFYTNFYPSNSSCQYDFFAKSN-EMIRLIFIVF--QTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKP-QSELCGTDSAIPSYFSS--SNFIRVRFLTDITSKGARGFQ 2342
P Y YP+N +C + A+ I L F F Q+S D C +D++ + + + + +Q RYCGTS+P ++S +L T+ F S++ GF A Y + CG + G +SP YP Y S+ C W++ A SP L+F SFQ+E S +C+ + I EG CG +++P +SS + + VRF++D + G GFQ
Sbjct: 1635 PLYPANYPNNQNCTWIIEAQPPFNHIALSFTHFHLQSSTD--------------CTRDFVEILD-GRDSDAPVQG----RYCGTSLPHPIISFGNAL--TVRFVSDSVYGFDGFHAIY------SASTSACGGTFYTGD--GIFNSPGYPEDYHSNTECVWNI-ASSPGNHLQLSFLSFQLE-NSLNCNKDFVEIREGNATGHLMGRYCG--NSLPGNYSSIEGHNLWVRFVSDGSGTGM-GFQ 1844 HSP 9 Score: 59.6918 bits (143), Expect = 1.536e-7 Identity = 127/551 (23.05%), Postives = 199/551 (36.12%), Query Frame = 3
Query: 699 PTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKV-----FSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGA 2330
P YP P+ NC + ++ I L F F+L Q C +FVEI++ DSD+ R CG S N L +R V + Y + + +Y +S G TF N+ +D+ TEC I S SPG L ++L+ C ++ I + +L+ RY CG N L +Y+S L + F GF+ RF FG + + G+ I +PF+ YP NS+ ++ S+ +I + ++ +LT+ +C D L + + + + T YCGT S+ T F S++ K+G GFL + + V CG + + + SP +PG Y + C W ++A P L S IE SCS L I +G + Q + LCG P S+ ++ +RF +D + GA
Sbjct: 1635 PLYPANYPNNQNCTWIIEAQPPFNHIALSFTHFHL-QSSTDCTRDFVEILD--GRDSDA-PVQGRYCGTSLPHPIISFGNALTVRFV--SDSVYGFDGFHA-IYSASTSACG----GTFYTGDGIFNSPGYPEDYHSNTECVWNIAS---------SPG--------------------------NHLQLSFLSFQLENSLNCNKDFVEIREGN-ATGHLMGRY-------------CG-NSLPGNYSSIE-GHNLWVRFVSDGSGTGMGFQA--RFKNIFGNDNIVGTHGK---------------IATPFWPGNYPLNSNYRWTVNVDSSHIIHGRIL------EMDIELTT------NCFYDSLKIYDGFDIHSRLIGT-----YCGTQRESFSSSRNS---LTFQFSSDSSKSGRGFLLEWFAVDVSNVTLPTIAPGACGGYMVTGDTPVFFFSPGWPGPYGNGADCIWIIYA--PDSTVELNILSMDIE-AQLSCSYDKLIIKDGDSRLSQQLAVLCGRSVPGP-IRSTGEYMYIRFTSDGSVTGA 2082 HSP 10 Score: 55.0694 bits (131), Expect = 4.381e-6 Identity = 52/166 (31.33%), Postives = 73/166 (43.98%), Query Frame = 3
Query: 1857 RYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG-FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
RYCG++ P + S SL F L S K G GF A ++ +CG + T YG I SP YPG Y C W+L VSP TF + +E + CS L I +G F+ P T + P ++ R+ F +D + +GF I +
Sbjct: 547 RYCGSTPPQGVHSSANSLYFHL--YSEYIKRGRGFTARWEAKLP------ECGGIL--TGNYGSITSPGYPGNYPPGRDCVWNL-LVSPGSLITFTFGTLSLE-SHNDCSKDYLEIRDGPFHHDPILGKFCTSLSTPPLQTTGPAARIHFHSD-SETSDKGFHITY 699
BLAST of Cubilin vs. UniProt/SwissProt
Match: sp|F1RWC3|CUBN_PIG (Cubilin OS=Sus scrofa OX=9823 GN=CUBN PE=1 SV=3) HSP 1 Score: 108.612 bits (270), Expect = 1.798e-22 Identity = 173/737 (23.47%), Postives = 271/737 (36.77%), Query Frame = 3
Query: 210 GILLSPNWP-GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANF--SFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEM--CPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNR-------------QDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNY--LKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
GI+ SP++ YP D+ +Y ++ + L F F++ +F C +DYL+IY + NIS +P+LG+FCG +L P N+ S NN + L F +D H + G+K +F + + Y S H+ +NG Y LNCI+ F + I+L F F L + C ++V++ + DS++ + CG F SS N L ++ V SSL+ GF +T D P YN +P T C I+ AP +H Q +E+ F ++ C YL E + +R P CG+N + Y+S + II+ F V +YR I+G C YQ G + SP + Y S++ C A N I L F F + C +D+L V + + L +YCGT +P + SQ + L L FKS++ +G G Y+ I CG + S G + SP YPG Y + CEW + ++P R + SF C L +Y+G N CG D+ + + +SS+ + +RF + ++ ++ W
Sbjct: 3048 GIIKSPSYSYSNYPNDMHCLYTVTVRDDRVIQLKFNDFDLVPSTF-CSQDYLEIY-------DGSNIS-----DPLLGKFCGSTL---PPNVKSSNNTMFLVFKTDSV---------HTAR-GWKISFRETLGPQQGCGGYLTGSTHTFGSPDSDSNGRYD-------------KNLNCIW-FITAPVNKLIKLTFSTFALEAATSLQRCIYDYVKLYDG---DSENANLAGTFCGSTVPAPFISSGNFLTVQFVS----------------DSSLEREGFNATYTLLDM--PCGGTYNATWTSQSIWSPSSSDPDVPLTTCTWVIE-------------------AP---------LH--QQVEITVWTF------QLHSQDCDQNYL-------EFRDPPER------NGNPGIRFCGRNASAVPTFYSSLSTAIII---FKSEVFNTDSRVGFTYR------IAG-------CSREYQKA----FGRLRSPGWPAGYASDADCAVVLRAPQNHTISLFFHAFGLEDSG------------GCTRDFLEVRNGSESTSPLLG-----KYCGTLLPNPIFSQSRDL--YLRFKSDSATSGRG----YEIIWTSS--PSGCGGTLYGDS--GLVTSPGYPGTYPNHTHCEWVI--IAPGGRPVTVSFSFISIDDPGECVQNYLMLYDGPDANSPSSGPYCGADTDVAPFAASSHRVFIRFHAEAAAR-PSALRLTWA 3624 HSP 2 Score: 102.449 bits (254), Expect = 1.391e-20 Identity = 166/719 (23.09%), Postives = 265/719 (36.86%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGE--ISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMK---DFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYR--GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQI 2345
LLSP+ G + + +YV EQ+ +NF H +EG S C + Y IEV+ + +LG+ CG+ P +I S N I + D + +A+F Y + G TGE I SP YP + P C + + + L+F F + C +++EI + P L S N + CG S +N L++ V SS +N GF KF+ TE + +S G I SPG N + G++ T ++ V + +L + + + C YL IY + + RY CGK+ ++ N LKL F +GF ++Y T S G + YR + SP + + YP+N C Y ++++ I L F F E + +C DY+ + G+ + +YCG++ P ++S L L FKS+ +GPGF A + CG N+++ + G SP+YP Y C W L + S F L F F +E +C+ L +Y+G + + LCG + P S+ + + ++ TD +G GF +
Sbjct: 719 LLSPDLSGPFTHSRQCIYVITQPLGEQIQVNFTHVELEGQS-GCSQSY----IEVRD------------DQTLLGKVCGNE---TPSHIKSITNSIWIRLKIDASV--------------VRASFGAAYQ------------------VACGGELTGEGVIRSPFYPNVYPGERICRWTIHQPQSQV-VLLNFTAFEM-GSSAHCDTDYIEIGSSPVLGSPEN---KKYCGTDIPSFITSVYNSLHVVFV----------------KSSSTENHGFMAKFS--------------------TEALACGEILTESSGIIQSPGHP---------NIYPHGVNCTWHILVQPGHLIHLEIRQFHLEFHYNCTRDYLEIYDTVSDTS--LGRY-------------CGKSIPPSLTSNTNS---LKLIFVADADLAYEGFVINYE--------ATDASAG------NTTALLYRRIWIFTSPNFPSNYPNNMECIYRITVETSQQIALHFTDFSLEEPIGG----------ACAADYVEIT-----NGGYASSPPLGKYCGSNPPPRIISHSNKL--WLKFKSDFFGSGPGFSAYWDGSLT------GCGGNLTTPT--GTFTSPNYPMPYYHSSECFWWLKS-SHGSPFELEFNDFHLE-YHPNCTLDYLDVYDGLSTSSHLLTRLCGNEKP-PLIRSTGDSMSLKLRTDEGQQGG-GFLV 1274 HSP 3 Score: 94.7449 bits (234), Expect = 3.197e-18 Identity = 170/740 (22.97%), Postives = 276/740 (37.30%), Query Frame = 3
Query: 177 YEHFYSNKMTG-GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFS---FKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVV---LAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTEC--DIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHL----SCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
Y+ ++TG G++ SP +P YP + + +++ V LNF F + G S C+ DY++I S+ + P ++CG IP I S N + + F +T+ +H GF A FS E++T+ +G I SP +P + P +NC + + I L+ F+L + C +++EI D+ S+ + R CG S+ N L L V LA +++ D + + ++ + F+ P N N EC I +++S Q + L+FT +L E C Y+ I + + + +Y CG N P R KL +F DF SG S + TG G + +P T P+ Y S+E F ++S P +L ++D HL +C DYL V + + + L R CG P ++ S S+ +L +++ + G GFL YQ C + + YG + S HYP YS + C W + A + TF +F++E + +CS L +Y+G PQ CG PS ++ + ++V F TD +G RGFQ+ W
Sbjct: 813 YQVACGGELTGEGVIRSPFYPNVYPGERICRWTIHQPQSQVVLLNFTAFEM-GSSAHCDTDYIEIG------------SSPVLGSPENKKYCGTD---IPSFITSVYNSLHVVFVKSSSTE------NH----GFMAKFSTEALACGEILTES-------------------SGIIQSPGHPNIYPHGVNCTWHILVQPG-HLIHLEIRQFHL-EFHYNCTRDYLEI-----YDTVSDTSLGRYCGKSIPPSLTSNTNSLKLIFVADADLAYEGFVINYEATDASAGNTTALLYRRIWIFTSPNFPSNYPNN-------MECIYRITVETSQQ-----------------------------------IALHFTDFSLEEPIGGACAADYVEITNGGYASSPPLGKY-------------CGSN--------------------PPPRIISHSNKLWLKFKSDFFGSGPGFSA-----YWDGSLTGCGGNLTTPTGTFTSPNYPMPYY----HSSE----CFWWLKSSHGSPFEL-EFNDFHLEYHPNCTLDYLDVYDGLSTSSHLLT-----RLCGNEKPPLIRSTGDSM--SLKLRTDEGQQGGGFLVKYQ---------QTCDNVVIVNRTYGILESIHYPKPYSVNQRCNWTIQATA-GNTVNYTFLAFELE-SHANCSTDYLELYDG----PQRMGRFCGA-VIPPSGSTTGSRLQVLFHTDGVGQGERGFQMQW 1388 HSP 4 Score: 93.9745 bits (232), Expect = 5.313e-18 Identity = 167/728 (22.94%), Postives = 273/728 (37.50%), Query Frame = 3
Query: 222 SPNWPGKYPQDVRYVYVFMGSEN-EQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFT------YLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNA---VLRIYEGFNVKP------QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
SP +P YP + ++ + L+F HF +E S +C +D+++I S P+ GR+CG S+ PH I S N ++L F SD + F GF A Y AS+ S+C + H G +SP YP + PS + C++ S S +++L FI F L + C +FVEI + + + R CG + N+ H+ L+++ V S +GF+ F N ++ DHI GT G + SP L P+ NY HN+ +V +N + L + F C L IY + LI Y CG +S T + L F+ +GF L + + ++ G C ++ + + SP + Y + + C + + + L + S D+ + H +C D L + + +N Q + CG IPG + S + + T+ F S+ GF AS F CG + + G I SP YP Y+S+L C WH+ + FQ+ C+ VL+ P CG+ + + F+S N + V+F++D +++G +GF+I +
Sbjct: 1636 SPRFPASYPNNQNCSWIIQAQPPFNHITLSFSHFGLESSS-TCTRDFVEILDGSHS------------DAPLRGRYCGSSM---PHPITSFGNALMLRFVSDSSVNFD----------GFHA-----------TYVAST--SACGGIFHM---AEGIFNSPGYPEVYPSNVECVWNIAS-SPGNQLQLSFITFQL-EDSRDCSRDFVEI----REGNATGRLVGRYCGNVLPLNYSSIIGHD-LWIKFVS----------------DGSGSGVGFQAAF---------NNIFG-NDHIVGTH------------GKVASP------LWPR--NY----PHNSNYQWIVNVNESQVIHGRILEMDVEGTFNCYYDKLRIYDGADIHSRLIGTY-------------CGAQTESFSSTGSS----LTFQFSSDSSISGRGFLLEWFAMDASDGPLPTIATGACGGFLRTGDAPV--FLYSPGWPGSYSNGADCMW-LIQAPDSTVELNIL----SLDI--------ESHRTCDYDKLVIRD---GDNNMAQ--ELAVLCGREIPGPIRSTGEYM--TIRFTSDFSVTRAGFNAS---------FHKSCGGYLHADR--GIITSPGYPEAYTSNLNCSWHVQVQQGLSIAVHFEQPFQVSNRDAFCNQGDYLVLKNGPDIYSPPLGPHGGNGRFCGSRPS-STLFTSDNELFVQFISDNSNEG-QGFKITY 2212 HSP 5 Score: 91.6633 bits (226), Expect = 2.768e-17 Identity = 154/746 (20.64%), Postives = 270/746 (36.19%), Query Frame = 3
Query: 114 DLFLMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPG-RYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKP-QSELCGTDSAIPSYFSSSNFIRVRFLTD--ITSKGAR 2333
DL++ F+S + + F F ++ + G G + SP WP YP + Y ++ +E++ +H ++EG +F+C D L IY H ++G +CG + + S + + F SD + G+ F+ ++ A+ +C + G + SP +PG + +C++ ++ + + + +D +R C D N + L VL GR +++ G + F+ + A +N H C + + G I SPG A + C++ Q + ++F +D C G + +K Y + + CG +TS N + + F E QGFK++Y K G + Y + ++ +GY + SP + + YP ++ C + A S IRL F + E P +SY ++ + +A ++CGTS+P +S + + L F+S+ GF A Y QCG ++ S G I S YP Y+++L CEW L +S + F F ++ S C + I+E CG ++ S +S N VRF+TD +T+ G R
Sbjct: 1829 DLWIKFVSDGSGSGVGFQAAFNNIFGNDHIVGTHGKVASPLWPRNYPHNSNYQWIVNVNESQVIHGRILEMDVEG-TFNCYYDKLRIYDGAD------------IHSRLIGTYCGAQTE----SFSSTGSSLTFQFSSDSSIS---------GRGFLLEWFAMDASDGPLPTIATG---ACGGFLRT-GDAPVFLYSPGWPGSYSNGADCMWLIQAPDSTVELNILSLDIE----------------------------SHRTCDY-DKLVIRDGDNNMAQELAVLCGREI----------PGPIRSTGEYMTIRFTSDFSVTRAGFNASFH---KSCGGYLHAD---RGIITSPGYPEAYTSNLNCSWHVQ----VQQGLSIAVHFEQPFQVSNRDAFCNQGDYLV------LKNGPDIYSPPLGPHGGNGRFCGSRPSSTLFTSDNELFV---QFISDNSNEGQGFKITYE-AKSLACGGNI-------YIHDADSSGY---VASPNHPDNYPQHADCIWVIAAPSGRPIRLEFEDQFSIEITPNCTSSYLELRDGADSNAPVLA----------------KFCGTSLPPSQLSSGEVM--YLRFRSDNSPTHAGFKAKYSIA--------QCGGTVTGQS--GVIESSGYPALPYANNLFCEWRLQGLS-GHYLTIHFEDFNLQ-NSSGCERDFVEIWENHTSGNLLGRYCG-NTVPDSIDTSGNVALVRFVTDGFLTASGFR 2444 HSP 6 Score: 85.8853 bits (211), Expect = 1.778e-15 Identity = 164/752 (21.81%), Postives = 272/752 (36.17%), Query Frame = 3
Query: 183 HFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQF----FSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGT--DSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV------IPRLSNGSCPGF 2396
H +++G G SP +P YP + ++ S + L F++E +C D L+IY FH P + + C P + S N + L F +D + G N S++ + C + A +GEI SP YP S C + + E R+ L+F DF+L QD C + F + + A RL G+ Q S+ + L++R R Q+ GF+ +F RQ C I + S I SP + + C++ I + L+F++ L C ++ I S L RY CG + + + TS ++L+ F GF +Y + S C + E G+ NSP Y YPSN C ++ + ++L FI FQ + C +D++ + E G RYCG +P + S + F S+ +G GF A++ +F + +I T +G + SP +P Y + +W ++ V+ + +EGT +C LRIY+G ++ S L GT + S+ S+ + + +F +D + G RGF + W + +P ++ G+C GF
Sbjct: 1391 HGCGGELSGDTGTFSSPGYPVGYPANKECIWYIHSSPGSSIQLTIHDFDVE-YHATCNFDVLEIY------------GGPDFHSPRIAQLCVQRSAENPMQVSSTGNELALRFKTDSSVN------------GRGFNVSWR-----------AVPGGCGGIFQAP---SGEIHSPNYPSPYRSNTECTWLIQVEKN-HRVLLNFTDFDLEPQDS-CIMAFDGL----------SSATARLVGVCGRQQLSNPIISTGSSLFVRFQSGPSR----------------QSRGFRAQF--------------RQ------ACGGHILT--DSFDTISSPRFPASYPNNQNCSWI---IQAQPPFNHITLSFSHFGLESSS--TCTRDFVEILDGSHSDAPLRGRY-------------CGSS-MPHPITSFGNALMLR--FVSDSSVNFDGFHATY-----------VASTSACGGIFHMAE----GIFNSPGYPEVYPSNVECVWNIASSPGNQLQLSFITFQLEDS------------RDCSRDFVEIRE------GNATGRLVGRYCGNVLP-LNYSSIIGHDLWIKFVSDGSGSGVGFQAAFN-----NIFGND---HIVGT--HGKVASPLWPRNYPHNSNYQWIVN-VNESQVIHGRILEMDVEGT-FNCYYDKLRIYDGADI--HSRLIGTYCGAQTESFSSTGSSLTFQFSSDSSISG-RGFLLEWFAMDASDGPLPTIATGACGGF 1983 HSP 7 Score: 78.1814 bits (191), Expect = 3.536e-13 Identity = 141/670 (21.04%), Postives = 236/670 (35.22%), Query Frame = 3
Query: 210 GILLSPNWPG-KYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTF-TSFQIEGTSKSCSNAVLRIYEG 2213
G++ S +P Y ++ + G + ++FE FN++ S CE+D+++I+ E + N +LGR+CG++ +P +I + NV ++ F +D + GF+ F S C + TG ++P Y P C + + R+ L D L + C E V + N + S+S + R + + + SS N + + R Y GF +T S+ +L N EG SPG + + N + ++ Q + ++F L +D CQ L + V LI R K T P + P + ++F R E GF+ Y F GI + G G+I+SP Y Y S + C + A I L F F + H SC D +TV R G + YCG+S P + S L + F +++ GF A++ + CG + S + G I SPH+P + + C W + P + ++F +F I C N+ ++++ G
Sbjct: 2347 GVIESSGYPALPYANNLFCEWRLQGLSGHYLTIHFEDFNLQNSS-GCERDFVEIW-ENHTSGN------------LLGRYCGNT---VPDSIDTSGNVALVRFVTDG----------FLTASGFRLRFD-------------SSMEGCGGDLQGP---TGTFTAPNYLNPNPHGWMCEWRITVQEG-RRVTLTLNDLRL-EAHPFCNSEHVAVFNG--IRSNSPQLEKRCSSVNGSNEIRSSGNTMKVVYFTDGSRPYG----------------GFTASYTSSEDAVCGGSLTN------------------SPEGNFTSPGYDGTRNYSRNLNCEWTLSNSNQGNSSIYIDFEDFYLESHQD--CQFDVLE-FRVDNADGLLIWRLCGSSKPTMPLVI---------------PYPQVWIHFVTNERVEHIGFRARYSFTDCGGI-----------------QIGDHGVISSPNYPASYDSLTHCSWLLEAPQGHTITLTFSDFDI------------EAHASCAWDSVTV-----RNGGSPGSPIIGHYCGSSNPRTIQSGSNQL--VVIFNTDSSVQNGGFYATW------NTETSGCGGILHSDT--GTIRSPHWPQNFPENSRCSWTV-ITHPSKHLEISFDNNFLIPSGDSQCLNSFVKVWAG 2872 HSP 8 Score: 71.2478 bits (173), Expect = 4.442e-11 Identity = 151/714 (21.15%), Postives = 250/714 (35.01%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFK--SNAHKNGPGFLASYQFIKKRK-----VFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDIT 2318
G + SPN+P Y + ++ +N +V LNF F++E + + + + S R L CG + + I+S + + + F S + Q GF+A F +C I + T ISSP +P P+ NC + +++ I L F F L + C +FVEI LD +DA R CG S N L LR V SS+ GF + S +++ +EG SPG + C + Q +QL+F L + +D C ++ I + + L+ RY CG +L LN++ + G L +F+ D SG + G G + SP + YP NS+ Q+ +++I + DV Y+D ++ + + + YCG S G +LTF+ S++ +G GFL + + + + CG + + +++SP +PG YS+ C W + A P L S IE + ++C L I +G N Q + LCG + P S+ ++ +RF +D +
Sbjct: 1521 GEIHSPNYPSPYRSNTECTWLIQVEKNHRVLLNFTDFDLEP-----QDSCIMAFDGLSSATAR------------LVGVCGRQQ--LSNPIISTGSSLFVRFQSGPSRQ----------SRGFRAQF----------------RQACGGHILTDSFDT--ISSPRFPASYPNNQNCSWIIQAQPPFNHITLSFSHFGL-ESSSTCTRDFVEI-----LDGSHSDAPLRGRYCGSSMPHPITSFGNALMLRFVS----------------DSSVNFDGFHATYVASTSA--CGGIFH------------------MAEGIFNSPGYPEVYPSNVECVWNIASSPGNQ----LQLSFITFQLEDSRD--CSRDFVEIREGNATGR-LVGRY-------------CGN--------------VLPLNYSSII-----GHDLWIKFVSDGSGSGVGFQAAFNNIFGNDHIVGTHGKVASPLWPRNYPHNSNYQWIVNVNESQVIHGRILEM----DVEGTFNCYYD-------------KLRIYDGADIHSRLIGTYCGAQTESF-----SSTGSSLTFQFSSDSSISGRGFLLEWFAMDASDGPLPTIATGACGGFLRTGDAPVFLYSPGWPGSYSNGADCMWLIQA--PDSTVELNILSLDIE-SHRTCDYDKLVIRDGDNNMAQELAVLCGREIPGP-IRSTGEYMTIRFTSDFS 2080 HSP 9 Score: 70.0922 bits (170), Expect = 1.106e-10 Identity = 71/285 (24.91%), Postives = 115/285 (40.35%), Query Frame = 3
Query: 132 LSITKIANSSIENIFYEHFYSNKM---------TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQ-DEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRL 956
L + + +SS EN + +S + + GI+ SP P YP V + + +HL F++E ++C +DYL+IY V + LGR+CG S IP ++ S N + L F +D + + GF N+ T A + + + I +SP +P P+ + CIY E T +I L F DF+L + C ++VEI N S+ + CG + S N+L+L+
Sbjct: 906 LHVVFVKSSSTENHGFMAKFSTEALACGEILTESSGIIQSPGHPNIYPHGVNCTWHILVQPGHLIHLEIRQFHLE-FHYNCTRDYLEIYDTVS--------------DTSLGRYCGKS---IPPSLTSNTNSLKLIFVADADLAYE----------GFVINYE------ATDASAGNTTALLYRRIWI-------FTSPNFPSNYPNNMECIYRITVE-TSQQIALHFTDFSLEEPIGGACAADYVEITNG---GYASSPPLGKYCGSNPPPRIISHSNKLWLKF 1145 HSP 10 Score: 56.6102 bits (135), Expect = 1.618e-6 Identity = 60/229 (26.20%), Postives = 96/229 (41.92%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKT--ERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEG---TSKSCSNAVLRIYEGFNVK--PQSELCGTDSAIPSYFSS 2279
G I SP + +P NS C + ++ + I F + +P+ D + VK G + +K CG PG +++ + + FT F+S GF AS F +CG N ++ S GYI SP+YP +Y +++ C + + A SP +L SF +E S SC + + I G ++ P LCG ++ P S
Sbjct: 2816 GTIRSPHWPQNFPENSRCSWTVITHPSKHLE---ISFDNNFLIPSG-------------DSQCLNSFVKVWAGTQEADKDLLATSCGNVSPGRIITPRNA--FTAVFQSQ-ETPAQGFSAS---------FLSRCGRNFTNPS--GYIVSPNYPKQYDNNMNCTYIIEA-SPLSVILLKVVSFHLEARSTVSGSCDSDGVHIIRGHSLSSTPLVTLCGDEALSPVTISG 3013
BLAST of Cubilin vs. UniProt/SwissProt
Match: sp|Q9TU53|CUBN_CANLF (Cubilin OS=Canis lupus familiaris OX=9615 GN=CUBN PE=1 SV=1) HSP 1 Score: 97.8265 bits (242), Expect = 4.154e-19 Identity = 177/737 (24.02%), Postives = 279/737 (37.86%), Query Frame = 3
Query: 195 NKMTGGILL--------SPNWPGKYPQDVRYVYVFMGSEN-EQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNA---VLRIYEGFNVKP------QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQI 2345
N++ GG +L SP +P KYP + +V + L+F+HF +E S +C +D+L+I + P+ GR+CGHS+ PH I S ++ + L F SD N D GF A ++ ASS S+C H G +SP YP + PS + C++ S S R++L FI F L + + C +FVE+ + + + R CG + N+ H L++R V S GF+ FT ++ D+I GT G I SP P NY + I N +V+ +++ + C L +Y LI Y CG +S +SRN L F+ +GF L + + G ++ G C ++ + + SP + Y +++ C + + + L + S D+ A+ T +D ++V R+ + CG IPG + S + + + F S+ G GF AS F CG + + G I SP YP YS +L C WH+ S + FQI SCS VL+ P CG+ + + F+S N + V+F++D S G +GF+I
Sbjct: 1614 NQVCGGHILTNSFDTISSPLFPAKYPNNQNCSWVIQAQPPFNHITLSFDHFGLES-STTCTQDFLEI------------LDGDYDDAPLRGRYCGHSM---PHPITSFSSALTLRFVSDSRV----NSD------GFHATYA-----------ASS--SACGGTFHM---AEGIFNSPGYPEVYPSNVECVWNIVS-SPGNRLQLSFITFQL-EDSQDCSRDFVEV----REGNATGHLVGRYCGNVLPLNYSSIVGH-ILWIRFVS----------------DGSGSGTGFQATFT---------KIFG-NDNIVGT------------HGKIASP--LWPGRYPHNSNYQW--IVNVNATQVIHGRILEIDIEGAQ--SCYYDKLRVYDGLGIHSRLIGTY-------------CGTQTTSFS-SSRNS---LTFQFSSDSSITGKGFLLEWFAVNASGGPLPTIATGACGGFLRTGDAPV--FLFSPGWPESYSNSADCTW-LIQAPDSTVELNIL----SLDIEAQRTCDYD-------------KLVIRDGDSNLAPQLAVLCGREIPGPIRSTGEYM--FIRFTSDFSITGAGFNAS---------FHKSCGGYLHADR--GIITSPQYPETYSPNLNCSWHVLVQSGLTIAVHFEQPFQIPSGDSSCSQGDYLVLKNGPDIYSPPLGPYGRNGHFCGSRPS-STLFTSDNQMFVQFISD-GSNGGQGFKI 2205 HSP 2 Score: 94.7449 bits (234), Expect = 3.629e-18 Identity = 166/729 (22.77%), Postives = 262/729 (35.94%), Query Frame = 3
Query: 177 YEHFYSNKMTG-GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFS---FKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
Y+ ++TG G++ SP +P YP + + +++ V LNF F IE S C+ DY++I S+ + P ++CG IP I S N + + F +T+ +H GF A FS E++T+ TG I SP +P + P +NC + + I L F F+L + C +++E+ D+ SN R CG SS N L L V S L GF I + +D + C ++ ++ G SP C Y + + + L+FT L E +C ++ I +E + Y I P +++ N L L FT GF + G++ G T G+ SP Y Y +S C + A L F F H +C DYL V + + L + CG P ++ S S+ L F+++ + G GFLA YQ + V ++ YG + S HYP YS + C W + A + TF +F++E +CS L +Y+G + CG D P+ ++ + ++V F TD +GFQ+ W
Sbjct: 809 YQVACGGELTGEGVIRSPFYPNVYPGERICRWTIHQPQSQVVILNFTAFGIES-SAHCDTDYIEIG------------SSSILGSPENKKYCGTD---IPLFITSVYNFLYVIFVKSSSTE------NH----GFMAKFSAADLACGEILTES-------------------TGIIQSPGHPNIYPHGINCTWHILVQPG-HLIHLIFRKFHL-EFHYNCTNDYLEV-----YDTGSNTYLGRYCGKSIPPSLTSSTNSLKLIFVA----------------DSDLAYEGFLINYEATDA---------------SSAC---MEDYTENSGTFTSPNFPNNYPNNWKCIYRIT----VETSQQIALHFTNFALEEAIGGQCVADFVEIRDGGYETSPPLGTYCGSIP---PPRIISHSNKLW-------------LQFTSDFLGSGPGFSAYW--------DGSLTGCG-------GNITTPTGVFTSPSYPMPYYHSSECYWLLKASHGSPFELEFEDFHLEH------------HPNCTLDYLAVYDGPSTSSHLL-----SQLCGNEKPPVIRSTGDSM--FLKFRTDEDQQGGGFLAKYQQTCRNVVIVNR---------NYGILESIHYPNPYSDNQRCNWTIQATT-GNTVNYTFLAFELE-NHINCSTDYLELYDG--PRRMGRYCGADMP-PTGSTTGSKLQVLFYTDGVGHQEKGFQMQW 1383 HSP 3 Score: 93.9745 bits (232), Expect = 5.930e-18 Identity = 177/738 (23.98%), Postives = 267/738 (36.18%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPV-EFVEIINQPQLDSDSNDADNR---LCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSD-QSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFT-YLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNF-YPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHL----SCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIP-GILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF-NVKPQSE-LCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGS 2384
L SP WP Y ++ + + V LN +IE +C+ D L I R SN+ P L CG IP I S + + F SD FS + GF A+F H SC +HA+ G I+SP YP LNC + +S L I + F F + D C +++ + N P + S R CG + + F+S N+++++ + S GFKIK+ C I D S GY+ SPG CN+ +++++ F N+ E + C YL E++ + ++ + LCG++ L S S V+ L+ F Q GFK+ Y +C R TG G+I S Y Y NS C++ S + + F D HL C +D++ + E N RYCG +IP I S +L + F ++ GF ++ + CG + + G SP+YP +CEW + V R LTF + ++E SC + + I+ G N PQ E LCG+ +A SS N ++V F TD S+ GF +T + GS
Sbjct: 1988 LFSPGWPESYSNSADCTWLIQ-APDSTVELNILSLDIEAQR-TCDYDKLVI---------RDGDSNL---APQLAVLCGRE---IPGPIRSTGEYMFIRFTSD----FS------ITGAGFNASF----------------HKSCGGYLHAD---RGIITSPQYPETYSPNLNCSWHVLVQSGLT-IAVHFEQPFQIPSGDSSCSQGDYLVLKNGPDIYSPPLGPYGRNGHFCGSRPSSTLFTSDNQMFVQFIS----------------DGSNGGQGFKIKY-----------------EAKSLACGGNIYIHDVNSAGYVTSPGHPNNYPQHADCNWLIAAPPG----KLIRVQFEDQFNIEETPN--CVSNYL-------ELRDGVDSNAPLLAK------LCGRS-LPSSQLSSGEVMYLR--FRSDNSSTQVGFKIKYAI-------------AQCGGRV----TGQSGIIESSGYPTLPYRDNSFCEWHLKGPSGHYLTIHF----------------EDFHLQNSSGCEKDFVEIWE------NHTSGNLLGRYCGNTIPDSIDTSSNVAL---VRFVTDGSVTASGFRLRFESSM------EACGGELQGPT--GTFTSPNYPNPNPHGRVCEWRI-MVQEGRRITLTFNNLRLE-AHPSCYSEHVTIFNGIRNNSPQLEKLCGSVNASSEIKSSGNTMKVVFFTD-GSRPFGGFSATYTSSEDAVCGGS 2570 HSP 4 Score: 91.2781 bits (225), Expect = 3.567e-17 Identity = 163/712 (22.89%), Postives = 265/712 (37.22%), Query Frame = 3
Query: 201 MTGGILLSPNWP-GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANF--SFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEM--CPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEV-VQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYS--YTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQS--ELCGTDSAIPSYFSSSNFIRVRF 2303
++ G++ SP + YP ++ +Y +G ++ V L F F++ +F C +DYL IY + NIS +P+LG+FCG +L P NI S N+ ++L F D G+K F + + Y S ++ +NG Y LNC++ F I+L F F L Q M C ++V++ + DS++ + CG F SS N L ++ V +L+ GF +T D P YN A+ P+ + N+ N EV + + +L P + K L ++S + YL R + P +CG+N Y+SR+ I++ F V +Y+ I+G C+ Y G + SP + + Y +N C A N I L F F + C D+L V + T YCGT +P + S+ L L FK+++ + G Y+ + CG + S G SP YPG Y ++ CEW + ++P R + +TF I+ C L +Y+G + S CG D+ I + +SS+ + ++F
Sbjct: 3040 VSTGVIKSPAYSYSDYPNNIYCLYTIVGRDDRVVQLKFSDFDVVPSTF-CSQDYLAIY-------DGSNIS-----DPLLGKFCGSNL---PPNIKSSNHSMLLVF----------KTDSFQTARGWKITFQQTLGPQQGCGGYLTGSDNTFASPDSDSNGRYD-------------KNLNCVW-FIIAPVNKLIKLTFNTFALEAQSAMQRCIYDYVKLYDG---DSENANLAGTFCGSTVPAPFISSGNFLTVQFVS----------------DVTLEREGFNATYTTVDM--PCGGTYN-------------------------------ATWTPQS-----ISSPNSSNPEVPLSMCMWFLEAPPHQQVKITVWALELHSQDCDQNYLEFR-DSPESNGSPGPQICGRNASATPTFYSSRSTAIVI---FKSEVLNRNSRVGFTYQ------IAG-------CNREYNKA----FGNLKSPGWPDNYDNNLDCTVILTAPQNHTISLFFHSFGIEDSS------------ECTHDFLEVRNGSDSSSPLFGT-----YCGTLLPDPIFSRNNKL--YLRFKTDSATSNRG----YEIVWTSS--PSGCGGTLYGDS--GSFTSPGYPGTYPNNTDCEWAI--IAPAGRPVTVTFYFISID-DPGDCVQNYLILYDGPDANSPSFGPYCGADTNIAPFVASSHRVFIKF 3603 HSP 5 Score: 90.8929 bits (224), Expect = 5.827e-17 Identity = 170/729 (23.32%), Postives = 273/729 (37.45%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGS----YTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDN---FQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSN-EMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSS--SNFIRVRFLTDITSKGARGFQIVWTRV 2360
GIL S ++P Y + R + + V+ F F +E +C DYL++Y + +GR+CG D P + + + +L F++D H K GF+ + IH G TG SSP YP P CI+ + + + + I+L DF++ + C + +E+ P S +LC + + Q S+ N L +R SS+ GF + +PG C Q+ + G I SP C++ I +N ++ LNFT +L E +D C Y + S + + +CG+ L TS + L+ F ++ +GF+ + V G H S +T I+SP + YP+N +C + A+ I L F F +C QD+L EI+ + + RYCG S+P + S +L TL F S++ N GF A+Y S CG G +SP YP Y S++ C W++ SP R L+F +FQ+E S+ CS + + EG N CG + +P +SS + + +RF++D + G GFQ +T++
Sbjct: 1286 GILESIHYPNPYSDNQRCNWTIQATTGNTVNYTFLAFELEN-HINCSTDYLELYDGPRR----------------MGRYCG--ADMPPTGSTTGSKLQVL-FYTDGV--------GHQEK-GFQMQ----------------------WFIHGCGGELSGTTGSFSSPGYPNTYPPNKECIW-YITTAPGSSIQLTIHDFDV-EYHARCNFDVLEVYGGPDFHSPR---ITQLCSQRSSENPMQVSSTGNELAIRFKT----------------DSSINGRGFNASW----------------QAVPGG-CGGIFQAPN---GEIHSPNYPSPYRGNTDCSWV---IRVERNHRIL-LNFTDFDL-EPQD-SCITAYDGLSSTTTRLA-----------------SVCGRQQLTNPITSSGNSLFLR--FQSGPSRQGRGFRAQFN----------QVCGG--HILTNSFDT-----ISSPLFPAKYPNNQNCSWVIQAQPPFNHITLSFDHFGLESST------------TCTQDFL---EILDGD--YDDAPLRGRYCGHSMPHPITSFSSAL--TLRFVSDSRVNSDGFHATY------AASSSACGGTFHMAE--GIFNSPGYPEVYPSNVECVWNI-VSSPGNRLQLSFITFQLE-DSQDCSRDFVEVREG-NATGHLVGRYCG--NVLPLNYSSIVGHILWIRFVSDGSGSGT-GFQATFTKI 1847 HSP 6 Score: 85.1149 bits (209), Expect = 2.759e-15 Identity = 162/718 (22.56%), Postives = 256/718 (35.65%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMI--RLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKR-----KVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG-FNVKPQ-SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGA 2330
G + SPN+P Y + +V N ++ LNF F++E + + Y + S R L CG + + I S N + L F S + Q GF+A F N++ C I N T ISSP +P P+ NC + +++ I L F F L + C +F+EI LD D +DA R CG S + L LR V S + + GF + S + C +EG SPG + C + + + +QL+F L + +D C ++ + + +L+ RY CG +L LN++ V G L RF+ D SGT G G I SP + YP NS+ Q+ + ++I R++ I + ++ SC+ D L V + + + + T YCGT S+ T F S++ G GFL + + + + CG + + ++ SP +P YS+ C W + A P L S IE ++C L I +G N+ PQ + LCG + P S+ ++ +RF +D + GA
Sbjct: 1516 GEIHSPNYPSPYRGNTDCSWVIRVERNHRILLNFTDFDLEP-----QDSCITAYDGLSSTTTR------------LASVCGRQQ--LTNPITSSGNSLFLRFQSGPSRQ----------GRGFRAQF----NQV------------CGGHILTNSFDT--ISSPLFPAKYPNNQNCSWVIQAQPPFNHITLSFDHFGL-ESSTTCTQDFLEI-----LDGDYDDAPLRGRYCGHSMPHPITSFSSALTLRFVS----------------DSRVNSDGFHATYAASS-----------------SACGGTFH---MAEGIFNSPGYPEVYPSNVECVWNIVSSPGNR----LQLSFITFQLEDSQD--CSRDFVEVREGN-ATGHLVGRY-------------CGN--------------VLPLNYSSIV-----GHILWIRFVSDGSGSGTGFQATFTKIFGNDNIVGTHGKIASPLWPGRYPHNSNYQWIVNVNATQVIHGRILEIDIEGAQ--------------SCYYDKLRVYDGLGIHSRLIGT-----YCGTQTTSFSSSRNS---LTFQFSSDSSITGKGFLLEWFAVNASGGPLPTIATGACGGFLRTGDAPVFLFSPGWPESYSNSADCTWLIQA--PDSTVELNILSLDIE-AQRTCDYDKLVIRDGDSNLAPQLAVLCGREIPGP-IRSTGEYMFIRFTSDFSITGA 2079 HSP 7 Score: 84.7297 bits (208), Expect = 4.430e-15 Identity = 86/321 (26.79%), Postives = 135/321 (42.06%), Query Frame = 3
Query: 1464 LKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTL--TFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV------IPRLSNGSCPGF 2396
L L F R GF +Y S C + E G+ NSP Y YPSN C ++ + ++L FI FQ + C +D++ V E G + RYCG +P ++ +G L F S+ +G GF A++ K+F + NI T +G I SP +PGRY + +W ++ V+ + IEG ++SC LR+Y+G + + CGT + S+ SS N + +F +D + G +GF + W V +P ++ G+C GF
Sbjct: 1709 LTLRFVSDSRVNSDGFHATY-----------AASSSACGGTFHMAE----GIFNSPGYPEVYPSNVECVWNIVSSPGNRLQLSFITFQLEDS------------QDCSRDFVEVRE------GNATGHLVGRYCGNVLP---LNYSSIVGHILWIRFVSDGSGSGTGFQATF-----TKIFGND---NIVGT--HGKIASPLWPGRYPHNSNYQWIVN-VNATQVIHGRILEIDIEG-AQSCYYDKLRVYDGLGIHSRLIGTYCGTQTT--SFSSSRNSLTFQFSSDSSITG-KGFLLEWFAVNASGGPLPTIATGACGGF 1978 HSP 8 Score: 79.337 bits (194), Expect = 1.860e-13 Identity = 152/710 (21.41%), Postives = 264/710 (37.18%), Query Frame = 3
Query: 258 RYVYVFMGSENEQVHLNFEHFNIE-GLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANG---SYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVV---LAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV 2360
+ +Y ++Q+ L+F +F +E + C D+++I Y+ P LG +CG P I+S +N + L F SD LG FS YW S L G + TG +SP+YP + C + ++ S + L+F DF+L + C ++++ + + P S S+ ++LCG + S+ + ++L+ G ++ + Y+ + +N+ + Y L +++ + C+ IQ++ T N +N+T+L C YL +Y M RY CG + T+ + + +L +T V +++GF++ + F+ G E +G G +SP Y N YP N C + I+L F + H C+ D L V + + ++R + P + S L + FK+++ NG GF AS+Q + CG + + G IHSP+YP Y + C W + V R +L FT F +E SC A Y+G + + +CG SS N + +RF + + +G RGF+ + +V
Sbjct: 1069 KCIYRITVETSQQIALHFTNFALEEAIGGQCVADFVEI--RDGGYET----------SPPLGTYCG---SIPPPRIISHSNKLWLQFTSDF--------------LGSGPGFS--------AYWDGS-------LTGCGGNITTPTGVFTSPSYPMPYYHSSECYWLLKA-SHGSPFELEFEDFHL-EHHPNCTLDYLAVYDGP---STSSHLLSQLCGNEKPPVIRSTGDSMFLKFRTDEDQQGGGFLAK------YQQTCRNV-----VIVNRNYGILESIHYPNPYSDNQRCNWTIQAT-------------------------------TGNT----VNYTFLAFELENHINCSTDYLELYDGPRRMG----RY-------------CGADMPPTGSTTGSKLQVLF--YTDGVGHQEKGFQMQW-FIHGCG----------------GELSGTTGSFSSPGYPNTYPPNKECIWYITTAPGSSIQLTIHDFDV------------EYHARCNFDVLEVYGGPDFHSPRITQLCSQR--SSENPMQVSSTGNEL--AIRFKTDSSINGRGFNASWQAVPG------GCGGIFQAPN--GEIHSPNYPSPYRGNTDCSWVIR-VERNHRILLNFTDFDLE-PQDSCITA----YDGLSSTTTRLASVCGRQQLTNPITSSGNSLFLRFQSGPSRQG-RGFRAQFNQV 1616 HSP 9 Score: 77.411 bits (189), Expect = 7.130e-13 Identity = 82/333 (24.62%), Postives = 140/333 (42.04%), Query Frame = 3
Query: 1389 TKPDQVLCGKNYLKYSYTSRNPVIILK---LNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTS--KSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRV 2360
+ P +CG L +PV IL LNF GFK +Y+ G+ G+I SP Y+ + YP+N C Y + + +++L F F VP+ C QDYL + + + L ++CG+++P + S S+ L FK+++ + G+ ++Q + CG ++ + GRY +L C W + ++P + I LTF +F +E S + C +++Y+G N CG+ P + SS NF+ V+F++D+T + GF +T V
Sbjct: 2989 STPFATVCGNEIL-------SPVTILGPVLLNFYSNAHTTDLGFKFNYKITSCGGVFNVST-----------------GVIKSPAYSYSDYPNNIYCLYTIVGRDDRVVQLKFSDFDV---VPSTF---------CSQDYLAIYDGSNISDPLLG-----KFCGSNLPPNIKSSNHSM--LLVFKTDSFQTARGWKITFQQTLGPQ---QGCGGYLTGSDNTFASPDSDSNGRYDKNLNCVWFI--IAPVNKLIKLTFNTFALEAQSAMQRCIYDYVKLYDGDSENANLAGTFCGSTVPAP-FISSGNFLTVQFVSDVTLE-REGFNATYTTV 3271 HSP 10 Score: 61.2326 bits (147), Expect = 5.819e-8 Identity = 144/699 (20.60%), Postives = 254/699 (36.34%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYT----GEISSPTYPGL--LPSTLNCIYEFRSESTL-ARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGI-KDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTV-AEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSK---SCSNAVLRIYEGFNVK--PQSELCGTDSAIP 2264
G SPN+P P + M E ++ L F + +E SC +++ I+ +++ + P L + CG S++ I S N + + FF+D + F GF A ++ SS + C GS T G +SP Y G+ LNC + + + + I + F DF L + + C + +E ++ + RLCG K + +++ V ++++GF +++F+D I++ S G I SP + + C++ + L F+ ++ + C +S+ + +I +Y + P + G N L + S + V + GF ++ + G G + S G I SP + +P NS C + ++ + I F + +P+ C ++ V A + L T CG PG +++ + F F+S GF AS F +CG N ++ S GYI SP+YP +Y +++ C + + A P +LTF SF +E S SC+N + I G N+ P + +CG + P
Sbjct: 2458 GTFTSPNYPNPNPHGRVCEWRIMVQEGRRITLTFNNLRLEAHP-SCYSEHVTIFNGIRN------------NSPQLEKLCG-SVN-ASSEIKSSGNTMKVVFFTDGSRPFG----------GFSATYT------------SSEDAVC------GGSLTHFPEGNFTSPGYNGVSNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYL-ESHQDCQFDVLEF----RVGNADGPLMWRLCGPSKPIVPLVIPYPEVWIHFVT----------------NEHVEHVGFHAEYSFTDCG------------------GIQLGES----GVIASPNYPASYDSLTHCSWLLEAPQGF----TITLTFSDFDIEDHA--TCAWDSVSVRNGGSPGSPIIGQY---CGTSNPRTIQSGSNQLVVIFNSDHSV-------------QNGGFYATWN-TQTLGCGGILHSD--------------NGTIRSPHWPQNFPENSRCSWTVITHESKQLE---ISFDNNFRIPSG-------DGQCQNSFVKVWAGTEEVAESLLATG-----CGNVAPGSILTPRNV--FIAVFQSQ-ETPAQGFSAS---------FVSRCGGNFTNPS--GYILSPNYPRQYDNNMNCTYIIEA-DPLSVVLLTFESFHLEARSAITGSCANDGVHIIRGSNLSSTPFATVCGNEILSP 3003
BLAST of Cubilin vs. UniProt/SwissProt
Match: sp|O60494|CUBN_HUMAN (Cubilin OS=Homo sapiens OX=9606 GN=CUBN PE=1 SV=5) HSP 1 Score: 94.7449 bits (234), Expect = 3.170e-18 Identity = 167/742 (22.51%), Postives = 278/742 (37.47%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKD-NFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTL--TFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEW--HLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW------TRVIPRLSNGSCPGF 2396
G SP +P +YP + ++ + L F++E S C D L+IY FH P + + C P + S N + + F +D + + GF A++ + +T C + A +GEI SP YP S +C + R + R+ L+F DF+L QD C + + + S + R CG + SS N L+LR R QN GF+ +F RQ C I +S S + SP + C++ I + + L+FT+ L + C ++ I E L RY CG + + + TS + + L+ F GF + ++ ++ + G Y + G+ NSP Y + YP N C ++ + ++L FI FQ + C +D++ + E G + RYCG S P ++ +G TL F S+ +G GF A++ K+F + NI T +G + SP +P Y + +W +++A IL +I+ +C LRIY+G ++ + CGT + S+ S+ N + F +D +S +GF + W V+P ++ G+C GF
Sbjct: 1400 GSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHS-RCNFDVLEIY------------GGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLS----------INGRGFNASW-----QAVT--------GGCGGIFQAP---SGEIHSPNYPSPYRSNTDCSWVIRVDRN-HRVLLNFTDFDLEPQDS-CIMAYDGL-------SSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSR----------------QNRGFRAQF--------------RQ------ACGGHILTS--SFDTVSSPRFPANYPNNQNCSWI---IQAQPPLNHITLSFTHFEL--ERSTTCARDFVEILDGGHEDAPLRGRY-------------CGTD-MPHPITSFSSALTLR--FVSDSSISAGGFHTT--------VTASVSACGGTFYMAE-------GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDS------------QDCSRDFVEIRE------GNATGHLVGRYCGNSFP---LNYSSIVGHTLWVRFISDGSGSGTGFQATFM-----KIFGND---NIVGT--HGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQ----NCYYDKLRIYDGPSIHARLIGAYCGTQTE--SFSSTGNSLTFHFYSD-SSISGKGFLLEWFAVDAPDGVLPTIAPGACGGF 1981 HSP 2 Score: 92.4337 bits (228), Expect = 1.530e-17 Identity = 162/724 (22.38%), Postives = 257/724 (35.50%), Query Frame = 3
Query: 210 GILLSPNWP-GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQD--EMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYR-----GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSE--LCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
GI+ SP + YP D+ +Y S+++ + L F F++ S SC DYL IY + N S +P+LG+FCG P N+ S NN ++L F D G+K +F + YL +N ++ S G+ LNC++ + I L F F L + C ++V++ + DS++ + CG F SS N L ++ + DL +L+ GF +T D P YN + + I SP + + IC + + ++ + V++ L L C YL + + R++ CG+N S PV ++ + K SG + R + YQ + G + SP + + Y ++ C A N I L F V C D+L V + L +YCGT +P + SQ L L FKS++ + G Y+ I CG + G SP YPG Y ++ CEW L V+P R + F C L +Y+G N S CG D++I + +SSN + ++F D + F++ W
Sbjct: 3046 GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVV-PSTSCSHDYLAIY-------DGANTS-----DPLLGKFCGSKR---PPNVKSSNNSMLLVF----------KTDSFQTAKGWKMSF---------RQTLGPQQGCGGYLTGSNNTFASPDSDSN--GMYDKNLNCVWIIIAPVNKV-IHLTFNTFALEAASTRQRCLYDYVKLYDG---DSENANLAGTFCGSTVPAPFISSGNFLTVQFIS-------------DL---TLEREGFNATYTIMDM--PCGGTYN----------------ATWTPQNISSPNSSDPDVPFSICTW----VIDSPPHQQVKITVWALQLTSQD---CTQNYLQLQDS--PQGHGNSRFQ-----------FCGRN------ASAVPVFYSSMSTAMVIFK-----------------SGVVNRNSRMSFTYQIADCNRDYHKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSV------------ECRNDFLEVRNGSNSNSPLLG-----KYCGTLLPNPVFSQNNEL--YLRFKSDSVTSDRG----YEIIWTSS--PSGCGGTLYGDR--GSFTSPGYPGTYPNNTYCEWVL--VAPAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARR-PSAFRLTW 3621 HSP 3 Score: 83.1889 bits (204), Expect = 1.192e-14 Identity = 66/240 (27.50%), Postives = 105/240 (43.75%), Query Frame = 3
Query: 1593 SEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTD 2312
+E G+I SPF+ N YP +C++ +++I L F VF+ +S H C DY+ + + L + + ++YCGT IP + S L T S+ +G F+ K CG ++ ++ G I SP +P Y + C WH+ V P L F +F +E +C+N L +Y+ + CG S PS SS N + + F+TD
Sbjct: 818 GDELTGEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIG-------SSAH-----CETDYVEIG-----SSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHG--------FMAKFSAEDLACGEILTEST--GTIQSPGHPNVYPHGINCTWHI-LVQPNHLIHLMFETFHLE-FHYNCTNDYLEVYDTDSETSLGRYCG-KSIPPSLTSSGNSLMLVFVTD 1027 HSP 4 Score: 78.9518 bits (193), Expect = 2.337e-13 Identity = 164/713 (23.00%), Postives = 263/713 (36.89%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
G L P G + + VY+ + EQ+ +NF H ++ C+ D YIEV+ E +LG+ CG+ I H I S N + + F D + + K F+A + + +T G I SP +P + P C + + I L+F F + C ++VEI + L S N + CG S +N LY+ V SS +N GF KF+ D C + +S G I SPG C + + Q ++ L F +L E + C + YL +Y E + RY CGK+ +S N ++++ F +GF ++Y + + C Y + G SP + N YP+N C Y ++ ++I + F F E + T D+L + R+ G+ ++ + G+++P ++S L L FKS+ GF A + S CG N++++S G SP+YP Y C W L + S F L F F +E +C+ L +Y+G N ++LCG D P SS + + ++ TD +G RGF+
Sbjct: 717 GELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQ-----CQSDSSQNYIEVRD------------GETLLGKVCGNGT--ISH-IKSITNSVWIRFKIDASVE----------KASFRAVYQVACGDELTG--------------------EGVIRSPFFPNVYPGERTCRWTIHQPQSQV-ILLNFTVFEI-GSSAHCETDYVEIGSSSILGSPEN---KKYCGTDIPSFITSVYNFLYVTFV----------------KSSSTENHGFMAKFSAED-----------------LACGEILT---ESTGTIQSPGHPNVYPHGINCTWHIL----VQPNHLIHLMFETFHL-EFH-YNCTNDYLEVYDTDSETS--LGRY-------------CGKSIPPSLTSSGNSLMLV---FVTDSDLAYEGFLINYEAIS---------AATACLQDYTDD----LGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYT-----------DFLEI-----RDGGYEKSPLLGIFYGSNLPPTIISHSNKL--WLKFKSDQIDTRSGFSAYWDGS------STGCGGNLTTSS--GTFISPNYPMPYYHSSECYWWLKS-SHGSAFELEFKDFHLE-HHPNCTLDYLAVYDGPSSNSHLLTQLCG-DEKPPLIRSSGDSMFIKLRTDEGQQG-RGFK 1271 HSP 5 Score: 78.9518 bits (193), Expect = 2.437e-13 Identity = 148/642 (23.05%), Postives = 243/642 (37.85%), Query Frame = 3
Query: 429 PVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLG--FTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFN--VKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
P+LG F G +L P I+S +N + L F SD+ S GF A YW S L ++G++ SP YP + C + +S A L+F DF+L + C ++++ + + P S ++ +LCG + SS + ++++L G+ Q GFK ++ RQ C+ + +Q+ G + S G + CN+ T N +N+T+L C YL +Y +M RY CG + T+ + + +L L T V + ++GF++ + +G G E +G G +SP + N YP N C + I+L F + H C+ D L EI + + + + C P + Q S G + FK++ NG GF AS+Q + + CG + S G IHSP+YP Y S+ C W + V R +L FT F +E ++ + Y+G + + + CG + SS N + +RF + S+ RGF+
Sbjct: 1118 PLLGIFYGSNL---PPTIISHSNKLWLKFKSDQIDTRS----------GFSA------------YWDGSSTGCGGNLTTSSGTFI----SPNYPMPYYHSSECYWWLKSSHGSA-FELEFKDFHL-EHHPNCTLDYLAVYDGP---SSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQ----------------QGRGFKAEY--------------RQ------TCE-NVVIVNQTYGILESIGYPNPYSENQHCNWTIRAT--TGNT----VNYTFLAFDLEHHINCSTDYLELYDGPRQMG----RY-------------CGVDLPPPGSTTSSKLQVLLL--TDGVGRREKGFQMQWFV---YGCGG--------------ELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDV------------EYHSRCNFDVL---EIYGGPD--FHSPRIAQLCTQRSPENPM-QVSSTGNELAIRFKTDLSINGRGFNASWQAV------TGGCGGIFQAPS--GEIHSPNYPSPYRSNTDCSWVIR-VDRNHRVLLNFTDFDLEP-----QDSCIMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSG-PSRQNRGFR 1613 HSP 6 Score: 78.5666 bits (192), Expect = 2.675e-13 Identity = 162/721 (22.47%), Postives = 250/721 (34.67%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFS-----DKYEPLNALYNRQDHI----PGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFK--SNAHKNGPGFLASYQFIKKRK-----VFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD 2312
G + SPN+P Y + +V N +V LNF F++E + + Y + S +R L R CG + + + IVS N + L F S + Q GF+A F I S +SSP +P P+ NC + +++ L I L F F L ++ C +FVEI LD DA R CG S + L LR V SS+ GF T S + ++N + P EC I SS PG NR +QL+F L + +D C ++ I + +L+ RY CG ++ LN++ V G L RF+ D SGT G G + SPF+ YP NS+ Q+ ++ ++ + E +C+ D L + + + YCGT S G +LTF S++ +G GFL + + + CG + + ++ SP +P YS+ + C W + A P L S IE + ++C+ L I +G N Q + LCG + P S+ ++ +RF +D
Sbjct: 1519 GEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEP-----QDSCIMAYDGLSSTMSR------------LARTCGR--EQLANPIVSSGNSLFLRFQSGPSRQ----------NRGFRAQFRQACGGHILT------------------SSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFEL-ERSTTCARDFVEI-----LDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVS----------------DSSISAGGFHTTVTASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSS---------PG-NR-----------------------LQLSFISFQLEDSQD--CSRDFVEIREGN-ATGHLVGRY-------------CGNSF--------------PLNYSSIV-----GHTLWVRFISDGSGSGTGFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEE------------IQNCYYDKLRIYDGPS-----IHARLIGAYCGTQTESF-----SSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTIAPGACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQA--PDSTVELNILSLDIE-SHRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGP-IRSTGEYMFIRFTSD 2076 HSP 7 Score: 75.485 bits (184), Expect = 2.449e-12 Identity = 149/686 (21.72%), Postives = 232/686 (33.82%), Query Frame = 3
Query: 267 YVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIIN-----QPQLDSDSNDADNRLCG-IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRV 2297
+ G + ++FE FN++ S CEKD+++I+ S +LGR+CG++ IP +I + +N ++ F +D + S GF+ F E S G +SP YP P C + + RI L F + L C E V + N PQL+ +LC + + + SS N + + R Y GF +T S+ +L N EG SPG + + N + + Q + ++F L +D CQ + + +R + LCG + K + P + ++F R E GF Y F GI + G G+I SP Y N Y S + C A I L F F + H +C D +TV R G ++ +YCG S P + S L +TF S+ G GF A++ + CG S + G I SPH+P + + C W K I +F I C N+ ++++ G ++ L CG + P S+ F V
Sbjct: 2365 WHLQGLSGHYLTISFEDFNLQNSS-GCEKDFVEIWDNHTSGN-------------ILGRYCGNT---IPDSIDTSSNTAVVRFVTDGSVTAS----------GFRLRFESSMEECGGDLQGS----------------IGTFTSPNYPNPNPHGRICEWRITAPEG-RRITLMFNNLRLATHPS-CNNEHVIVFNGIRSNSPQLE--------KLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYG----------------GFTASYTSSEDAVCGGSLPN------------------TPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQD--CQ--------------FDVLEFRVGDADGPLMWRLCGPS--KPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSFTDCGGI-----------------QIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDI------------EPHTTCAWDSVTV-----RNGGSPESPIIGQYCGNSNPRTIQSGSNQL--VVTFNSDHSLQGGGFYATW------NTQTLGCGGIFHSDN--GTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAV 2901 HSP 8 Score: 75.0998 bits (183), Expect = 3.129e-12 Identity = 163/733 (22.24%), Postives = 264/733 (36.02%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMC-PVEFVEIINQPQLDSDSNDADN---RLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNF-YPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNV-KPQSE-LCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCP 2390
L SP WP Y V ++ + + V LN +IE +C D L I R +N+ VL CG IP I S + + F SD + + GF A+F H SC +HA+ G I+SP YP PS LNC + +S L I + F F + D C +++ + N P + S CG + F+S N+++++ + S + GFKIK+ + + L N + I +D S GY+ SP C + T+ +QL F E+ C YL E++ + ++ + CG + ++S ++ L F GFK Y S +C R G G++ S + Y N C++ S + + F ED + +S C +D++ + + N RYCG +IP + + + + F ++ GF ++ ++CG ++ + G SP+YP ICEW + A + R L F + ++ T SC+N + ++ G PQ E LC + + SS N ++V F TD S+ GF +T + GS P
Sbjct: 1991 LFSPGWPDSYSNRVDCTWLIQ-APDSTVELNILSLDIESHR-TCAYDSLVI---------RDGDNNLAQQLAVL---CGRE---IPGPIRSTGEYMFIRFTSDSSVT----------RAGFNASF----------------HKSCGGYLHAD---RGIITSPKYPETYPSNLNCSWHVLVQSGLT-IAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFIS----------------DHSNEGQGFKIKY----EAKSLACGGN-----------VYIHDAD-SAGYVTSPNHPHNYPPHADCIWILAAPPETR----IQLQFEDRFDIEVTP-NCTSNYL-------ELRDGVDSDAPILSK------FCGTSLPSSQWSSGE---VMYLRFRSDNSPTHVGFKAKY-------------SIAQCGGRVP----GQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISF------EDFNLQNSS------GCEKDFVEIWD------NHTSGNILGRYCGNTIPDSIDTSSNTA--VVRFVTDGSVTASGFRLRFESSM------EECGGDLQGS--IGTFTSPNYPNPNPHGRICEWRITAPEGR-RITLMFNNLRL-ATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTD-GSRPYGGFTASYTSSEDAVCGGSLP 2575 HSP 9 Score: 74.3294 bits (181), Expect = 5.798e-12 Identity = 101/408 (24.75%), Postives = 163/408 (39.95%), Query Frame = 3
Query: 1155 GYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP--GRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTS--KSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
GYIISP + C Y + + VV L F +L S + ++I+ Y + + P +CG + T PV+ LNF + GFK SYR + G+ + + S G+I SP Y+ YP++ C Y +++I L F F VP+ SC DYL + + + L ++CG+ P + S S+ L FK+++ + G+ S+ R+ Q G T SP G Y +L C W + ++P + I LTF +F +E S + C +++Y+G N CG+ P + SS NF+ V+F++D+T + GF +T
Sbjct: 2929 GYIISPNYPKQYDNNMNCTY----VIEANPLSVVLLTFVSFHLEARSAVT--------GSCVNDGVHIIRGYSVM---STPFATVCGDE-MPAPLTIAGPVL---LNFYSNEQITDFGFKFSYRIISCGGV-----------FNFSS------GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDV---VPST---------SCSHDYLAIYDGANTSDPLLG-----KFCGSKRPPNVKSSNNSM--LLVFKTDSFQTAKGWKMSF-----RQTLGPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWII--IAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGSTVPAP-FISSGNFLTVQFISDLTLE-REGFNATYT 3272 HSP 10 Score: 70.8626 bits (172), Expect = 6.719e-11 Identity = 167/724 (23.07%), Postives = 266/724 (36.74%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFE-HFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPD-QVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGT---DSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
+ G + SPN P YP +++ ++ L FE F+IE ++ +C +YL++ V S P+L +FCG SL P + S V+ L F SD N H +GFKA +S + C + I PT P L C + + S + + F DFNL Q C +FVEI + + S + R CG I D+ +S N +R V S+ GF+++F S + EC +Q S G SP + +IC + E ++ + NL C + ++ +++ I+ P + LC + S ++ +K+ F + GF SY +D G++ + ++ GY G+ N Y N +C++ + N+ I I F+ D +L HQD ++++ G R CG S P + + S + + F +N GF A Y F+D G I + G I SP+YP Y S C L A P+ I LTF+ F IE +C+ + + G P+S + G +S + S SN + V F +D + +G GF W
Sbjct: 2228 SAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIE-VTPNCTSNYLELRDGVDS------------DAPILSKFCGTSL---PSSQWSSGEVMYLRFRSD-------NSPTH---VGFKAKYSI---------------AQCGGRVPGQSGVVESIGHPTLP--YRDNLFCEWHLQGLSG-HYLTISFEDFNL-QNSSGCEKDFVEIWD----NHTSGNILGRYCGNTIPDSID--TSSNTAVVRFVT----------------DGSVTASGFRLRFESSME-----------------ECGGDLQG---SIGTFTSPNYPNPNPHGRICEWRITA------PEGRRITLMFNNLRLATHPSCNNEHVIVFN--------------GIRSNSPQLEKLCSS--VNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCGGSLPNTPEGNFT----SPGYDGVRN-------YSRNLNCEWT-LSNPNQGNSSISIHFE-------------DFYLESHQD--CQFDVLEFRVGDADGPLMWRLCGPSKPTLPLVIPYSQVW-IHFVTNERVEHIGFHAKYS-------FTDCGGIQIGDS---GVITSPNYPNAYDSLTHCSSLLEA--PQGHTITLTFSDFDIE-PHTTCAWDSVTVRNG--GSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGG-GFYATW 2798 HSP 11 Score: 67.0106 bits (162), Expect = 9.059e-10 Identity = 145/699 (20.74%), Postives = 254/699 (36.34%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGL--LPSTLNCIYEFRSESTL-ARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADN----RLCGI-KDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTV-AEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSK---SCSNAVLRIYEGFNV--KPQSELCGTDSAIP 2264
G SPN+P P + E ++ L F + + SC +++ ++ ++S + P L + C S + + I S N + + FF+D + + GF A+++ SS + C + + G +SP Y G+ LNC + + + + I + F DF L + + C + +E DAD RLCG K ++++++ V +++IGF K++F+D C IQ D G I SP A + C+ + L F+ ++ C +++ + +I +Y + P + G N L ++ S + + + GF ++ + G G S G I SP + +P NS C + ++ + I F + +P+ C ++ V A + + L T CG PG +++ + FT F+S GF AS F +CGSN + S GYI SP+YP +Y +++ C + + A +P +LTF SF +E S SC N + I G++V P + +CG + P
Sbjct: 2461 GTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRL-ATHPSCNNEHVIVFNGIRS------------NSPQLEKLC--SSVNVSNEIKSSGNTMKVIFFTDGSRPYG----------GFTASYT------------SSEDAVCGGSLP--NTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYL-ESHQDCQFDVLEF--------RVGDADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVT----------------NERVEHIGFHAKYSFTD-------------------CG-GIQIGD--SGVITSPNYPNAYDSLTHCSSLLEAPQG----HTITLTFSDFDIEPHT--TCAWDSVTVRNGGSPESPIIGQY---CGNSNPRTIQSGSNQLVVTFNSDHSL-------------QGGGFYATWN-TQTLGCGGIFHSD--------------NGTIRSPHWPQNFPENSRCSWTAITHKSKHLE---ISFDNNFLIPSG-------DGQCQNSFVKVWAGTEEVDKALLATG-----CGNVAPGPVITPSNT--FTAVFQSQ-EAPAQGFSAS---------FVSRCGSNFTGPS--GYIISPNYPKQYDNNMNCTYVIEA-NPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAP 3006 HSP 12 Score: 60.4622 bits (145), Expect = 9.336e-8 Identity = 53/193 (27.46%), Postives = 83/193 (43.01%), Query Frame = 3
Query: 1773 HLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
H +C DYL V + + L + CG P ++ S S+ L +++ + G GF A Y+ + V +Q YG + S YP YS + C W + A + TF +F +E +CS L +Y+G + CG D P +SS ++V LTD + +GFQ+ W
Sbjct: 1215 HPNCTLDYLAVYDGPSSNSHLLT-----QLCGDEKPPLIRSSGDSMFIKL--RTDEGQQGRGFKAEYRQTCENVVIVNQ---------TYGILESIGYPNPYSENQHCNWTIRATT-GNTVNYTFLAFDLE-HHINCSTDYLELYDG--PRQMGRYCGVDLPPPGSTTSSK-LQVLLLTDGVGRREKGFQMQW 1386 HSP 13 Score: 57.7658 bits (138), Expect = 6.616e-7 Identity = 60/246 (24.39%), Postives = 97/246 (39.43%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYEHFYSNKMTGG--ILLSPNWPGKYPQDVRYVYVFMGSEN-EQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEI 845
LFL F S N F + + +T + SP +P YP + ++ + L+F HF +E S +C +D+++I + P+ GR+CG + PH I S ++ + L F SD + + GF + S FY+ G +SP YP + P + C++ S S R++L FI F L + + C +FVEI
Sbjct: 1597 LFLRFQSGPSRQNRGFRAQFRQACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELE-RSTTCARDFVEI------------LDGGHEDAPLRGRYCGTDM---PHPITSFSSALTLRFVSDSS----------ISAGGFHTTVTASV----------SACGGTFYMAE------GIFNSPGYPDIYPPNVECVWNIVS-SPGNRLQLSFISFQL-EDSQDCSRDFVEI 1798 HSP 14 Score: 56.6102 bits (135), Expect = 1.289e-6 Identity = 43/146 (29.45%), Postives = 68/146 (46.58%), Query Frame = 3
Query: 129 FLSITKIANSSIEN-IFYEHFYSNKMTGGILL--------SPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQF 539
FL +T + +SS EN F F + + G +L SP P YP + + + N +HL FE F++E ++C DYL++Y + S E LGR+CG S IP ++ S N ++L F +D + +
Sbjct: 905 FLYVTFVKSSSTENHGFMAKFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLE-FHYNCTNDYLEVY-DTDS-------------ETSLGRYCGKS---IPPSLTSSGNSLMLVFVTDSDLAY 1032
BLAST of Cubilin vs. TrEMBL
Match: A0A267FHN8 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029467g1 PE=4 SV=1) HSP 1 Score: 417.542 bits (1072), Expect = 4.682e-126 Identity = 262/804 (32.59%), Postives = 413/804 (51.37%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSF----KYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQD-----------EMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQD-HIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFT-YLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLC-------GKNYLKYSYTSRNPVIILKLNFTQPVRKEQ--QGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTN----FYPSNSSCQYDFFA-KSNEMIRLIFIVFQTSEDVPAKLTSYHDVH-----LSCHQDYLTVAEIVKRENGF-LQTNKTERYCGTSIPGILVS----QQKSLGFTLTFKSNAH-----KNGPGFLASYQFIKKRKVFSDQ-CGSNISSTSYYGYIHSPHYP-GRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFS-SSNFIRVRFLTDITSKGARGFQIVWTRVIP-RLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNN 2477
+ SP WP YP+D+R Y +G +E+V L+F FN+EGL C+KD+LD++I++K + + P+LGRFCGH++D IP IVS+++V+++DF+SDKNTQ YN D HM LGFKA ++F KY E + S++ C YLI + G + S TYPGL P ++C+Y F+++ R+RL F D +LY+ + CPV+ + N + CG + N FSS + L L + GR + D + +Q GF++K+T SD++ +++ H+ GTECD I+S +S+ + P + ++ C F G+HN Q EVVQ+ ++ + CQ +S Y + + L+ ++PD C S S P + L+L +GF L YRF+ D+GI G +S C + Y S ++ RGL NSP + + YP+N +C F A + +E++R+ F F + L + H ++C D + + +I NG + ++ YCGTSIPG VS ++ + F T+ H + GF Y F K+ + + CG I S + G I P P +++SD+ICEW +H P+ + + F F +EG++KSCS AV+RIY G + P SE+CG+D++IP+++ + +R+R +T S+G RG + WT V+ +NG CPGF+C + HCI +L CN++ NCG+ V+N
Sbjct: 78 VTSPGWPKHYPEDLRCRYKLIGRSDEKVRLDFVEFNVEGLGPLCKKDFLDVHIQLKEANASVETT------PLLGRFCGHTIDAIPRTIVSQHSVLVMDFYSDKNTQRVYNNDMHMRVLGFKAKYTFVPKAKY-EPGHRILGSTNE--CSYLISS--PEEGTLLSATYPGLYPDNMHCVYIFQAKPN-QRVRLVFEDLDLYEIAGESIEQSVHVIDSCPVDVIRFYNSRE---QRQQIQGDFCGSRPNLTIFSSGSELRLDFISGVGRVSRTRDLSSDSESAEIQRRGFRLKYTMSDEFLRIDSPSALMKYHLNGTECDFLIESQGRSQEQLFFPPVRPGTM----CRIFLQGVHNRQKTEVVQVELNRFVRNSNSEKRACQSATISAY---LKGQGLMN--------SRPDSRFCQLQDDSAASTAKPISLRSEGPQMFLELRTGSEFSNSDSSKGFVLRYRFITDYGIPGVPLSEDICQFTYHSSQSS-RGLTNSPLFNSRTKAHYPNNITCLLRFIADRPDELVRIRFTHFYVEDFYVESLNNDKRHHSTGSYVTCVGDRVELFDIYDVPNGTEPRKDRVSTYCGTSIPGPYVSHLDTRELQVRFVSTWDKQPHEQYGRRTATGFQIEYDFPSKKSLMPNHYCGGKIISPKHGGIIKIPRDPKAQHASDVICEWKIHPNRPENKVFVQFPEFHLEGSTKSCSMAVVRIYRGDSHIPSSEICGSDNSIPAFYGETGQHVRLRLITTRGSRGGRGLKFAWTEVLNIESANGICPGFRCNRTKHCIDHSLECNRLPNCGTVVSN 850
BLAST of Cubilin vs. TrEMBL
Match: A0A267GBW1 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029467g2 PE=4 SV=1) HSP 1 Score: 414.461 bits (1064), Expect = 5.864e-125 Identity = 261/804 (32.46%), Postives = 412/804 (51.24%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSF----KYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQD-----------EMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQD-HIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFT-YLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLC-------GKNYLKYSYTSRNPVIILKLNFTQPVRKEQ--QGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTN----FYPSNSSCQYDFFA-KSNEMIRLIFIVFQTSEDVPAKLTSYHDVH-----LSCHQDYLTVAEIVKRENGF-LQTNKTERYCGTSIPGILVS----QQKSLGFTLTFKSNAH-----KNGPGFLASYQFIKKRKVFSDQ-CGSNISSTSYYGYIHSPHYP-GRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFS-SSNFIRVRFLTDITSKGARGFQIVWTRVIP-RLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNN 2477
+ SP WP YP+D+R Y +G +E+V L+F FN+EGL C+KD+LD++I++K + + P+LGRFCGH++D IP IVS+++V+++DF+SDKNTQ YN D HM LGFKA ++F KY E + S++ C YLI + G + S TYPGL P ++C+Y F+++ R+RL F D +LY+ + CPV+ + N + CG + N FSS + L L + GR + D + +Q GF++K+T SD++ +++ H+ GTECD I+S +S+ + P + ++ C F G+HN Q EVVQ+ ++ + CQ +S Y + + L+ ++PD C S S P + L+L +GF L YRF+ D+GI G +S C + Y S ++ RGL NSP + + YP+N +C F A + +E++R+ F F + L + H ++C D + + +I N + ++ YCGTSIPG VS ++ + F T+ H + GF Y F K+ + + CG I S + G I P P +++SD+ICEW +H P+ + + F F +EG++KSCS AV+RIY G + P SE+CG+D++IP+++ + +R+R +T S+G RG + WT V+ +NG CPGF+C + HCI +L CN++ NCG+ V+N
Sbjct: 78 VTSPGWPKHYPEDLRCRYKLIGRSDEKVRLDFVEFNVEGLGPLCKKDFLDVHIQLKEANASVETT------PLLGRFCGHTIDAIPRTIVSQHSVLVMDFYSDKNTQRVYNNDMHMRVLGFKAKYTFVPKAKY-EPGHRILGSANE--CSYLI--SSPEEGTVLSATYPGLYPDNMHCVYIFQAKPN-QRVRLVFEDLDLYEIAGESIEQSVHVIDSCPVDVIRFYNSRE---QRQQIQGDFCGSRPNLTIFSSGSELRLDFISGVGRVSRTRDLSSDSESAEIQRRGFRLKYTMSDEFLRIDSPSALMKYHLNGTECDFLIESQGRSQEQLFFPPVRPGTM----CRIFLQGVHNRQKTEVVQVELNRFVRDSNSEKRACQSATISAY---LKGQGLMN--------SRPDSRFCQLQDDSAASTAQPISLRSEGPQMFLELRTGSEFSNSDSSKGFVLRYRFITDYGIPGVPLSEDICQFTYHSSQSS-RGLTNSPLFNSRTKAHYPNNITCLLRFIADRPDELVRIRFTHFYVEDFYVESLNNDKRHHSTGSYVTCVGDRVELFDIYDVPNRTEPRKDRVSTYCGTSIPGPYVSHLDTRELQVRFVSTWDKQPHEQYGRRTATGFQIEYDFPSKKSLMPNHYCGGKIISPKHGGIIKIPRDPKAQHASDVICEWKIHPNRPENKVFVQFPEFHLEGSTKSCSMAVVRIYRGDSHIPSSEICGSDNSIPAFYGETGQHVRLRLITTRGSRGGRGLKFAWTEVLNIESANGICPGFRCNRTKHCIDHSLECNRLPNCGTVVSN 850
BLAST of Cubilin vs. TrEMBL
Match: A0A1I8JCS6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 402.519 bits (1033), Expect = 7.724e-121 Identity = 275/810 (33.95%), Postives = 401/810 (49.51%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHM---GKLGFKANFSFKYN---EMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDS-NDADNRL-------CGIKDNFQFFSSHNRLYLRLVVLAGR-NYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQL---NFTYLNLPEMKDFKCQD--GYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLC-----------GKNYLKYSYTSRNPVIILKLNFTQPVRKEQ--QGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNF----YPSNSSCQYDFFA-KSNEMIRLIFIVFQTSEDVPAKLTS---YHDV--HLSCHQDYLTVAEIVK--RENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSN----AH-----KNGPGFLASYQFIKKRKVFS---DQCGSNISSTSYYGYIHSP-HYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFS-SSNFIRVRFLTDITSKGARGFQIVWTRVIP-RLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGS 2465
+ SP WP YP+D R Y F+ NE+V LNF FN+EGL SCEKD+LD+Y E++ + N S L H P+LGRFCGH L +P +VS ++V++LDF++D NTQ YN D+HM LGFKA +SF E + A S + S F + ++ G I+SP YPGL P L+C Y FR R+RL F + ++Y+ E I+ +DS D+D RL CG K S+ +R+ L + AGR + DL LQ GF++++ S +Y ++ R +H+ GTECD I+S+ +S P + ++C FF G+HN Q E+ L ++ +D +C G+L +Y+ R + PD C G + S P + L + T+ + Q F ++YRF+ DFGI G + C + Y S G NSPF+ YP N++C Y F A + N+ +R+ F F + +L + +H V ++ C D + + E + + +G + K YCGTSIPG V+Q + + F S AH + GF Y F + +FS D CG NISS + G I P + Y DLICEWH++ P + + F F +EG++KSCS AVLR+Y G + P SE+CG D+ IP+++ S +R+R LT S+G +GF+ WT + G CPGFQC + HCI L CN++ NCGS
Sbjct: 97 VTSPGWPRPYPEDARCRYKFVAGRNEKVRLNFLAFNVEGLGPSCEKDFLDVYTELE----QENAS--LLHSPLLGRFCGHILASVPRTVVSLHSVLVLDFYTDGNTQKVYNNDNHMAMEAALGFKAQYSFVPKADYEPGPRLLAYSGNCS-FLMETSSADIDGVINSPGYPGLYPDNLHCNYLFRGFGN-QRVRLQFEELDIYEIHAETFGEAGHTISSCPIDSVRIYDSDQRLRQIHSDFCGQKAGLTVVSTGSRMRLEFITSAGRIPRSRTVTSADL--GELQRKGFRLRYNISSEYLRIDRGL-RSNHLTGTECDFLIESAGKSHDRFQFPSVRGG----RLCRVFFQGVHNLQRSEMTLLRIDGMAHITAGRRQDGRCPGLAGHLKVYA------------RGQGADAVPDADFCQAVGEASDGRGGSLGEPQEFRSSGPQLFLVFD-TRHLETWQLAPAFIINYRFVPDFGIPGHQPNEDDCAFEYVSGADKAHGRTNSPFFNPVTKAHYPHNTTCSYRFVATEPNQRVRIRFTHFYVEDFFIEELGNDKKHHTVGSYVPCAGDRVEIYERYESPKNSGRFRLEKILTYCGTSIPGPYVTQFDTQELLVLFHSTWDKWAHPEYDKRTASGFQIEYDFPVRTSLFSNKFDVCGGNISSDMHGGVIQVPKNEQATYQPDLICEWHIYPSQPGNQVFVQFPEFHLEGSTKSCSMAVLRMYNGDSHVPSSEVCGADNGIPAFYGRGSEHVRIRLLTTAGSRGGKGFKFSWTEALKIHPGTGHCPGFQCKRTRHCIDHRLECNRLPNCGS 878
BLAST of Cubilin vs. TrEMBL
Match: A0A267F4R1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012127g1 PE=4 SV=1) HSP 1 Score: 402.905 bits (1034), Expect = 1.674e-120 Identity = 275/810 (33.95%), Postives = 401/810 (49.51%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHM---GKLGFKANFSFKYN---EMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDS-NDADNRL-------CGIKDNFQFFSSHNRLYLRLVVLAGR-NYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQL---NFTYLNLPEMKDFKCQD--GYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLC-----------GKNYLKYSYTSRNPVIILKLNFTQPVRKEQ--QGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNF----YPSNSSCQYDFFA-KSNEMIRLIFIVFQTSEDVPAKLTS---YHDV--HLSCHQDYLTVAEIVK--RENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSN----AH-----KNGPGFLASYQFIKKRKVFS---DQCGSNISSTSYYGYIHSP-HYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFS-SSNFIRVRFLTDITSKGARGFQIVWTRVIP-RLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGS 2465
+ SP WP YP+D R Y F+ NE+V LNF FN+EGL SCEKD+LD+Y E++ + N S L H P+LGRFCGH L +P +VS ++V++LDF++D NTQ YN D+HM LGFKA +SF E + A S + S F + ++ G I+SP YPGL P L+C Y FR R+RL F + ++Y+ E I+ +DS D+D RL CG K S+ +R+ L + AGR + DL LQ GF++++ S +Y ++ R +H+ GTECD I+S+ +S P + ++C FF G+HN Q E+ L ++ +D +C G+L +Y+ R + PD C G + S P + L + T+ + Q F ++YRF+ DFGI G + C + Y S G NSPF+ YP N++C Y F A + N+ +R+ F F + +L + +H V ++ C D + + E + + +G + K YCGTSIPG V+Q + + F S AH + GF Y F + +FS D CG NISS + G I P + Y DLICEWH++ P + + F F +EG++KSCS AVLR+Y G + P SE+CG D+ IP+++ S +R+R LT S+G +GF+ WT + G CPGFQC + HCI L CN++ NCGS
Sbjct: 70 VTSPGWPRPYPEDARCRYKFVAGRNEKVRLNFLAFNVEGLGPSCEKDFLDVYTELE----QENAS--LLHSPLLGRFCGHILASVPRTVVSLHSVLVLDFYTDGNTQKVYNNDNHMAMEAALGFKAQYSFVPKADYEPGPRLLAYSGNCS-FLMETSSADIDGVINSPGYPGLYPDNLHCNYLFRGFGN-QRVRLQFEELDIYEIHAETFGEAGHTISSCPIDSVRIYDSDQRLRQIHSDFCGQKAGLTVVSTGSRMRLEFITSAGRIPRSRTVTSADL--GELQRKGFRLRYNISSEYLRIDRGL-RSNHLTGTECDFLIESAGKSHDRFQFPSVR----GGRLCRVFFQGVHNLQRSEMTLLRIDGMAHITAGRRQDGRCPGLAGHLKVYA------------RGQGADAVPDADFCQAVGEASDGRGGSLGEPQEFRSSGPQLFLVFD-TRHLETWQLAPAFIINYRFVPDFGIPGHQPNEDDCAFEYVSGADKAHGRTNSPFFNPVTKAHYPHNTTCSYRFVATEPNQRVRIRFTHFYVEDFFIEELGNDKKHHTVGSYVPCAGDRVEIYERYESPKNSGRFRLEKILTYCGTSIPGPYVTQFDTQELLVLFHSTWDKWAHPEYDKRTASGFQIEYDFPVRTSLFSNKFDVCGGNISSDMHGGVIQVPKNEQATYQPDLICEWHIYPSQPGNQVFVQFPEFHLEGSTKSCSMAVLRMYNGDSHVPSSEVCGADNGIPAFYGRGSEHVRIRLLTTAGSRGGKGFKFSWTEALKIHPGTGHCPGFQCKRTRHCIDHRLECNRLPNCGS 851
BLAST of Cubilin vs. TrEMBL
Match: A0A1I8IC59 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 401.749 bits (1031), Expect = 6.670e-120 Identity = 275/810 (33.95%), Postives = 401/810 (49.51%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHM---GKLGFKANFSFKYN---EMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDS-NDADNRL-------CGIKDNFQFFSSHNRLYLRLVVLAGR-NYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQL---NFTYLNLPEMKDFKCQD--GYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLC-----------GKNYLKYSYTSRNPVIILKLNFTQPVRKEQ--QGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNF----YPSNSSCQYDFFA-KSNEMIRLIFIVFQTSEDVPAKLTS---YHDV--HLSCHQDYLTVAEIVK--RENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSN----AH-----KNGPGFLASYQFIKKRKVFS---DQCGSNISSTSYYGYIHSP-HYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFS-SSNFIRVRFLTDITSKGARGFQIVWTRVIP-RLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGS 2465
+ SP WP YP+D R Y F+ NE+V LNF FN+EGL SCEKD+LD+Y E++ + N S L H P+LGRFCGH L +P +VS ++V++LDF++D NTQ YN D+HM LGFKA +SF E + A S + S F + ++ G I+SP YPGL P L+C Y FR R+RL F + ++Y+ E I+ +DS D+D RL CG K S+ +R+ L + AGR + DL LQ GF++++ S +Y ++ R +H+ GTECD I+S+ +S P + ++C FF G+HN Q E+ L ++ +D +C G+L +Y+ R + PD C G + S P + L + T+ + Q F ++YRF+ DFGI G + C + Y S G NSPF+ YP N++C Y F A + N+ +R+ F F + +L + +H V ++ C D + + E + + +G + K YCGTSIPG V+Q + + F S AH + GF Y F + +FS D CG NISS + G I P + Y DLICEWH++ P + + F F +EG++KSCS AVLR+Y G + P SE+CG D+ IP+++ S +R+R LT S+G +GF+ WT + G CPGFQC + HCI L CN++ NCGS
Sbjct: 164 VTSPGWPRPYPEDARCRYKFVAGRNEKVRLNFLAFNVEGLGPSCEKDFLDVYTELE----QENAS--LLHSPLLGRFCGHILASVPRTVVSLHSVLVLDFYTDGNTQKVYNNDNHMAMEAALGFKAQYSFVPKADYEPGPRLLAYSGNCS-FLMETSSADIDGVINSPGYPGLYPDNLHCNYLFRGFGN-QRVRLQFEELDIYEIHAETFGEAGHTISSCPIDSVRIYDSDQRLRQIHSDFCGQKAGLTVVSTGSRMRLEFITSAGRIPRSRTVTSADL--GELQRKGFRLRYNISSEYLRIDRGL-RSNHLTGTECDFLIESAGKSHDRFQFPSVRGG----RLCRVFFQGVHNLQRSEMTLLRIDGMAHITAGRRQDGRCPGLAGHLKVYA------------RGQGADAVPDADFCQAVGEASDGRGGSLGEPQEFRSSGPQLFLVFD-TRHLETWQLAPAFIINYRFVPDFGIPGHQPNEDDCAFEYVSGADKAHGRTNSPFFNPVTKAHYPHNTTCSYRFVATEPNQRVRIRFTHFYVEDFFIEELGNDKKHHTVGSYVPCAGDRVEIYERYESPKNSGRFRLEKILTYCGTSIPGPYVTQFDTQELLVLFHSTWDKWAHPEYDKRTASGFQIEYDFPVRTSLFSNKFDVCGGNISSDMHGGVIQVPKNEQATYQPDLICEWHIYPSQPGNQVFVQFPEFHLEGSTKSCSMAVLRMYNGDSHVPSSEVCGADNGIPAFYGRGSEHVRIRLLTTAGSRGGKGFKFSWTEALKIHPGTGHCPGFQCKRTRHCIDHRLECNRLPNCGS 945
BLAST of Cubilin vs. Ensembl Cavefish
Match: cubn (cubilin [Source:NCBI gene;Acc:103044622]) HSP 1 Score: 122.865 bits (307), Expect = 9.324e-28 Identity = 170/734 (23.16%), Postives = 281/734 (38.28%), Query Frame = 3
Query: 207 GGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFI-DFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYH-DVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQ-CGSNISSTSYYGYIHSP--HYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKS-CSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNG 2381
GG + SP +P YP R V++ E + L F +F +E S C D + IY + P++G++CGHS P I S +N + + F +D + + + GF A + ++ S C IHA+ +G I SP YP P+ + C + + + + F DF + C ++++ + P+ ++D+ A CG + +N ++ R S + +G +F T C + S G ++SP A C+Y N + V+ L F + E + DG +K Y P LCG N + +T+ P++ LNF GF Y + G+ G G ++SP + + Y N +C Y +N +I L K S+H + +C DY+ + + L ++CGT +P L + L + FK+++ G G+ ASY + + +Q CG ++++S G SP Y G+Y + + C W + VS + L+F +F++EG S S C ++IY+G N CGT P + SSSNF+ V F++D S RGF ++ V RL G
Sbjct: 2705 GGTVSSPGYPDSYPSPSRCVWLLEAPEGHTITLTFTYFEVEEHS-QCSWDSVTIYNGASA------------GSPIIGQYCGHSS---PGTIQSGSNKLTVVFLADHS----------VSRGGFIATW-------------TTDSSGCGGTIHAD---SGTIKSPNYPQNFPANVECSWTIIAHEG-NHLEMGFASDFQIPDSSGQCQSSYIKVWSGPRAENDALLATG--CGSTAPPAVIAPYNVIHARF-------------------QSTETVGKGFSSSFY------------------TRCGANFSA---SAGRVVSPNYPDLYPASSNCDYLI----NAGDQTVIFLTFRTFQI-EAESTCVYDG--------------VKIYSGTSVNGNPVATLCG-NTIPGPFTTFGPML---LNFYSDFIINDNGFLAEYTAIPCGGVF-----------------NGTSGSVSSPTHAISNYHHNINCTYHITVSNNRIIEL-------------KFNSFHLEASSTCAFDYVALYDGPNTLAPLLG-----KFCGTELPPTLKTTSNDL--FIVFKTDSSVTGEGWRASY----RETLGPEQGCGGYLTASS--GMFGSPDIDYNGKYENYMDCLWTI-TVSSNKAINLSFLTFELEGMSSSVCRYDYVQIYDGDSVNYPLVGTFCGTTVPAP-FVSSSNFLTVHFVSD-GSVSFRGFNATYSAV-DRLCGG 3283 HSP 2 Score: 120.939 bits (302), Expect = 4.021e-27 Identity = 177/769 (23.02%), Postives = 289/769 (37.58%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVK--PQSELCGTDSAIPSYF-SSSNFIRVRFLTDITSKGARGFQIVWTRV-----IPRLSNGSCPG 2393
L ++F S I+ ++Y++ ++G G SP++P KYP + V+ S V + F+IE SC+ D L++Y P L + C P + S N + + F SD +++ GF A+ W + +I + +GEI SP YP P+ ++C + + RI +F D ++ + C ++V++ + P DS+ ++CG +S+ N +Y+R R+ + H GFK +F+ C I + D G I SP + CN+ + + V L+FT L EM + C + I + RY CG N + + TS + +++ NF ++GF+ +Y + T G H G NSP Y + YP N C + + ++L F++F+ + C+ DYL + E G L R+CG S+P S + + F S++ +G GF R FS G++I+ TS G I SP YP Y + W + VS + F IE C L+I++G NV P CG +P SS + + + F +D T G RGF + WT + +P +S G+C G
Sbjct: 1380 LHVIFNSDLSISLPGFRMLWYQNGCGGDLSGPSGNFTSPDYPNKYPDNRECVWYIQTSPGSSVTITIHEFDIESHP-SCDFDLLEVY------------GGPDLSSPRLAQLCTTRPPNNPLQVSSTGNTVTVRFKSD----------EYISGRGFSAS------------WQETQGGCGGPII----APSGEIHSPQYPNNYPNNVDCSWVITVDQG-HRILFNFTDVDI-ESHSSCQWDYVDVHDGP---GDSSPLLAKVCGFSVPAPIYSTQNVIYVRF-----RSDISGNHR-----------GFKAEFS--------------------EACGSTIMADDVG-GAIASPNYPYPYPNNQNCNWIIIA---QEPFNHVTLSFTDFEL-EMINSNCSHDAVEILDGDNSDAPSVGRY-------------CG-NDVPHPVTSFSNALVV--NFVTDASVTRKGFRATY-------TASTSGCGGNLHME--------SGAFNSPNYPDAYPPNIECVWTIISSPGNRLQLSFVLFELQQST------------GCNNDYLEIRE--GNSTGAL----VGRFCGNSLPSNYTSLIGHV-LWVKFVSDSSVSGAGF---------RATFSHLYGNDITGTS--GQIASPLYPRTYPVNADYRWTI-TVSGDSYIQIRFLDIDIEDL-YDCYYDQLKIFDGPNVHALPLGVFCGL--LLPGLVRSSGSTVTLEFKSD-TVIGGRGFLVEWTAIQNSGPLPTISPGACGG 1997 HSP 3 Score: 117.857 bits (294), Expect = 2.910e-26 Identity = 164/719 (22.81%), Postives = 280/719 (38.94%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANG--SYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRL---VVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKY-LIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSN---FIRVRFLTDITSKG 2327
T GIL+SPNWP Y + + VY+ + +E V LNF H +E S CE DY+++ R ++ +P++G++CG +L P I+S N + + F SD + + GF+A Y I G S +G+I +P +P P C + + L+F+ F++ + C ++VE+ + + S+ R CG + S+ ++Y+ + + E Y S++Q G T +D + + + D+ G C I ++PG +++L+FT NL + C Y+ IY + L+ RY CG++ ++ N + IL F +GF +Y L + C Y++ G++ SP Y + YPS C Y + N I L F F+ + +C DY+ + R+ GF + RYC P I++S L + FKS+ GF A + + CG + T+ G SP+YP Y + C WH+ V+ L F F +E +S C L +Y+G N + ++LCG + IP+ +S+ ++++R + I++ G
Sbjct: 718 TEGILISPNWPNNYAHNKQCVYLIRVARSETVLLNFTHMELEPHS-GCEFDYVEV---------RDGLAET---DPLIGKYCGSTL---PAPILSSYNHLWIRFKSDSSVSHA----------GFRA----------------------VYEISCGGTLSGSGQIRTPLHPDAYPHNKKCEWVINQAEGYV-VTLNFLTFDV-EDSAGCYFDYVEVRDGA---TSSSPLLGRFCGTQVPPMLQSTQKQMYIVFNTDASVTNHGFTAE------YASAIQGCGD----TLTDPTGTITSPGHPTDYPHGANCTWYIS---------VAPG------------------------NIIRLSFTTFNLEYHTN--CNYDYVEIYDNGTALTGNLLGRY-------------CGRSVPPSLTSTDNLMTIL---FVSDSSLSTEGFSANYVSLN---------ATTDCSAEYRTP----TGVLTSPNYPSNYPSTRECVYKIIVEINMQIMLNFTDFEL------------EGGSNCPFDYVEI-----RDGGFETSPLIGRYCSNQPPPIVISHSNML--WILFKSDFTATARGFSAHWDGTQT------GCGGTL--TTSVGSFTSPNYPLPYHPNAECYWHIK-VNAGSSIQLNFEDFHLE-SSTDCYYDYLAVYDGNSTNDRQLAKLCG--NQIPNPITSTRDQMYVKLRTDSIISAGG 1278 HSP 4 Score: 104.76 bits (260), Expect = 3.175e-22 Identity = 178/762 (23.36%), Postives = 286/762 (37.53%), Query Frame = 3
Query: 153 NSSIENIFYEHFYSNKMTG---------GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTE--CDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSA-IPSYFSSS-NFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG 2393
++S+ N + Y++ + G G + SP P YP + + + L+F FN+E +C DY++IY + + LGR+CG S +P ++ S +N++ + F SD + + GF AN+ A++ S+ + + TG ++SP YP PST C+Y+ E + +I L+F DF L + CP ++VEI R G + + L GR +P I + S++ I FK FT + + H GT+ C + +S G SP P Y+ + ++ + +QLNF +L D C YL++Y + + + LCG N + TS + +KL + GF SY SG +++ G+I S + N YP N+ C + I F F P SC DY+ + E + R+CG + P + SL + F S+ + PGF + + + CG ++S S G SP YP +Y + C W++ SP +T F IE + SC +L +Y G ++ ++LC T P SS+ N + VRF +D G RGF W + G C G
Sbjct: 920 DASVTNHGFTAEYASAIQGCGDTLTDPTGTITSPGHPTDYPHGANCTWYISVAPGNIIRLSFTTFNLE-YHTNCNYDYVEIYDNGTALTGNL-----------LGRYCGRS---VPPSLTSTDNLMTILFVSDSS----------LSTEGFSANY--------VSLNATTDCSAEYR------TPTGVLTSPNYPSNYPSTRECVYKIIVEINM-QIMLNFTDFEL-EGGSNCPFDYVEI---------------RDGGFETS---------------PLIGRYCSNQPPPIVISHSNMLWILFKSDFTATAR--------GFSAHWDGTQTGCGGTLTTS---VGSFTSPNY-PLPYHPNAECYWHIKVNAGSS---IQLNFEDFHLESSTD--CYYDYLAVYDGNSTNDRQLAK-------------LCG-NQIPNPITSTRDQMYVKLRTDSIISA--GGFVASYTS----NCSGIVIANKT------------SGVIESQNFPNNYPFNARCSWTIQTTMGNTINYTFTAFDLEGLSP-----------SCIYDYMLLYNGPNEEAPLIG-----RFCGNTPPPAGATTSSSL--HVIFNSDLSISLPGF--------RMLWYQNGCGGDLSGPS--GNFTSPDYPNKYPDNRECVWYIQ-TSPGSSVTITIHEFDIE-SHPSCDFDLLEVYGGPDLSSPRLAQLCTTRPPNNPLQVSSTGNTVTVRFKSDEYISG-RGFSASWQE-----TQGGCGG 1525 HSP 5 Score: 104.76 bits (260), Expect = 3.667e-22 Identity = 172/720 (23.89%), Postives = 281/720 (39.03%), Query Frame = 3
Query: 201 MTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSK-NNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFR-SESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRL---VVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNIS--STSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD--ITSKG 2327
M G SPN+P YP ++ V+ + S ++ L+F F ++ S C DYL+I N + L +GRFCG+SL P N S +V+ + F SD + + GF+A FS Y IT +G+I+SP YP P +N Y + + S + I++ F+D ++ + C + ++I + P + + CG+ SS + + L V+ GR +++E +++QN G PL + PG C + D ++ SPG + C + +T V+LN +L++ + + C L I + + R LCG+ +T+R+ + L FT +GF SY S+G C ++ RG+++SP Y Y N C + S + + F+ P ++ Y + DYL + + L R CGTS+P V+Q + F S+A G GF ++ S CG I GYI SP YP Y ++ C W + V E L F F IE ++ C+ L I +G N ++LCG ++ + S+++ + +RF TD +T KG
Sbjct: 1762 MESGAFNSPNYPDAYPPNIECVWTIISSPGNRLQLSFVLFELQ-QSTGCNNDYLEI--------REGNSTGAL-----VGRFCGNSL---PSNYTSLIGHVLWVKFVSDSS----------VSGAGFRATFSHLYGNDIT-------------------GTSGQIASPLYPRTYP--VNADYRWTITVSGDSYIQIRFLDIDIEDLYD-CYYDQLKIFDGPNVHALPLGV---FCGLLLPGLVRSSGSTVTLEFKSDTVIGGRGFLVE-------WTAIQNSG------------PLPTIS------PGA-CGGALMPGDTPR-FLFSPGWPNEYEPNQECTWVIRSPDST-----VELNLLFLDIED--EASCLYDSLVIRDGETNLSPELAR-------------LCGRQLPGSIHTTRDSMF---LRFTSDYSINGRGFNASY-------------SKG-CGGLLHTD----RGVLSSPNYPQNYKPNQDCSWHVMVTSGFRVSVTFLT-------PFQVQGYGTACST--GDYLELRNGPDADAPSLG----GRLCGTSVPA--VTQTTDNHLHVRFVSDASNEGNGFKLIFE------AHSTACGGTIELKDGDPPGYITSPDYPSNYPQNIDCVW-IIMVPNGESVQLDFEDFYIEPNTQ-CAYDYLEIRDGVNSDTDLIAKLCG-NTKPSTQHSTASAMYLRFRTDQSVTHKG 2337 HSP 6 Score: 102.064 bits (253), Expect = 2.553e-21 Identity = 171/704 (24.29%), Postives = 254/704 (36.08%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPV-EFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNF-YPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF--NVKPQSELCGTDSAIPSYFSSSNFIRVRFLTD 2312
L SP WP +Y + +V S + V LN +IE + SC D L I N+S P L R CG L P +I + + + L F SD +S N GF A++S C L+H + G +SSP YP +C + S R+ + F+ F + C +++E+ N P D+D+ RLCG ++ N L++R V A S + GFK+ F + H I+++ D GYI SP C + M N E VQL+F + + +C YL I LI + + TKP T + + L F +GFK Y GT + G G I SP Y + YP NS+C++ + + L + C DY+ + E +G L R+CG S+P + V S + + F S+ N PGF SY+ ++CG ++++ S G I SP+YP Y + +C W + V R LT ++E SCS + + G N CG+ A SS N + V F TD
Sbjct: 2008 LFSPGWPNEYEPNQECTWVIR-SPDSTVELNLLFLDIEDEA-SCLYDSLVIR------DGETNLS------PELARLCGRQL---PGSIHTTRDSMFLRFTSD----YSIN------GRGFNASYS----------------KGCGGLLHTD---RGVLSSPNYPQNYKPNQDCSWHVMVTSGF-RVSVTFLTPFQVQGYGTACSTGDYLELRNGP--DADAPSLGGRLCGTSVPAVTQTTDNHLHVRFVSDA----------------SNEGNGFKLIF---------------EAHSTACGGTIELKDGDP-PGYITSPDYPSNYPQNIDCVWIIM----VPNGESVQLDFEDFYI--EPNTQCAYDYLEIRDGVNSDTDLIAK---LCGNTKPS-------------TQHSTASAMYLRFRTDQSVTHKGFKAKYSIAV---CGGTYI--------------GQSGTIRSPGYPDSNYPDNSNCEWYLEGPTGHYLTLSYSALNLQSST------------GCVNDYVEIREY--NASGRL----LGRHCGMSLP-LSVDTGDSFAY-VKFVSDGSVNAPGFSLSYE------ASVEECGGDLNAAS--GTISSPNYPNLYPHNRVCRWRI-TVPQGRRVTLTINDLRLE-DHGSCSFDYVEVINGLVANSPRLQRFCGSVPAGTQVKSSGNTMTVVFATD 2561 HSP 7 Score: 101.293 bits (251), Expect = 3.770e-21 Identity = 179/755 (23.71%), Postives = 284/755 (37.62%), Query Frame = 3
Query: 96 ILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTG-GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
IL+ L++ F S + ++++ + YE ++G G + +P P YP + + +V +E V LNF F++E S C DY+++ S P+LGRFCG +P + S + K +N D + GF A + AS+ L TG I+SP +P P NC + + S + IRL F FNL + C ++VEI + + + + R CG S+ N + + V SSL GF S Y LNA T+C + ++ G + SP + + C Y + N Q + LNFT L + C Y+ I FE LI RY P V+ N L I+ K +FT R GF + + G GT+ + G SP Y Y N+ C + + I+L F F L S D C+ DYL V + + + + CG IP + S + + L ++++ + GF+ASY + C + + G I S ++P Y + C W + TFT+F +EG S SC + +Y G N + CG ++ P+ ++S+ + V F +D+ S GF+++W
Sbjct: 794 ILSSYNHLWIRFKSDSSVSHAGFRAV-YEISCGGTLSGSGQIRTPLHPDAYPHNKKCEWVINQAEGYVVTLNFLTFDVED-SAGCYFDYVEVRDGATS------------SSPLLGRFCGTQ---VPPMLQS----------TQKQMYIVFNTDASVTNHGFTAEY------------ASAIQGCGDTLTDP----TGTITSPGHPTDYPHGANCTW-YISVAPGNIIRLSFTTFNL-EYHTNCNYDYVEIYDNGT--ALTGNLLGRYCGRSVPPSLTSTDNLMTILFVS----------------DSSLSTEGF------SANYVSLNAT---------TDCSAEYRTP---TGVLTSPNYPSNYPSTRECVYKIIVEINMQ----IMLNFTDFELEGGSN--CPFDYVEIRDGGFETSPLIGRY---CSNQPPPIVISHSNMLW---------ILFKSDFTATAR----GFSAHWDGTQT-GCGGTLTTS--------------VGSFTSPNYPLPYHPNAECYWHIKVNAGSSIQLNFEDFH--------LESSTD----CYYDYLAVYDGNSTND-----RQLAKLCGNQIPNPITSTRDQMYVKL--RTDSIISAGGFVASY---------TSNCSGIVIANKTSGVIESQNFPNNYPFNARCSWTIQTTM-GNTINYTFTAFDLEGLSPSCIYDYMLLYNGPNEEAPLIGRFCG-NTPPPAGATTSSSLHVIFNSDL-SISLPGFRMLW 1399 HSP 8 Score: 100.138 bits (248), Expect = 9.735e-21 Identity = 163/718 (22.70%), Postives = 266/718 (37.05%), Query Frame = 3
Query: 210 GILLSPNWP-GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIIN-----QPQLDSDSNDADNRLCG-IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI-CNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFL-TDITSKG 2327
G + SP +P YP + + G + L++ N++ S C DY +E++ Y N S L LGR CG SL P ++ + ++ + F SD + FS Y + + + +S G ISSP YP L P C + R+ L D L + C ++VE+IN P+L R CG + Q SS N + VV A SS+ N GF ++ SD+ + + + G SP + + + C + ++ + VV ++ +L + C+ YL + + E L+ R +CG+ + P + + + V GFK++Y F D G YQ TG G ++SP Y + YPS S C + A I L F F+ E H C D +T+ + + +YCG S PG + S L T+ F ++ + GF+A++ S CG I + S G I SP+YP + +++ C W + A + + FQI +S C ++ ++++ G + + L CG+ +A P+ + N I RF T+ KG
Sbjct: 2356 GTIRSPGYPDSNYPDNSNCEWYLEGPTGHYLTLSYSALNLQS-STGCVNDY----VEIREY----NASGRL-----LGRHCGMSL---PLSVDTGDSFAYVKFVSDGSVN--------------APGFSLSYEASVEECGGDLNAAS------------GTISSPNYPNLYPHNRVCRWRITVPQG-RRVTLTINDLRL-EDHGSCSFDYVEVINGLVANSPRL--------QRFCGSVPAGTQVKSSGNTM---TVVFA-------------TDSSVSNGGFNADYS-SDEAAVCGGVLD-------------------TPGNFTSPDYGIGNYSNSLNCEWLIQNPNHVNSSIVVLIDDMHLEHHQT----CEWDYLE-FRLGDENAELLGR-------------ICGQTVPEVPIVVSTPQLWVHFRSDESVVD--LGFKVTYYF-SDCG-------------GYQ---TGEGGTVSSPGYPDSYPSPSRCVWLLEAPEGHTITLTFTYFEVEE------------HSQCSWDSVTIYNGASAGSPIIG-----QYCGHSSPGTIQSGSNKL--TVVFLADHSVSRGGFIATW------TTDSSGCGGTIHADS--GTIKSPNYPQNFPANVECSWTIIAHEGNHLEMGFASDFQIPDSSGQCQSSYIKVWSGPRAENDALLATGCGS-TAPPAVIAPYNVIHARFQSTETVGKG 2919 HSP 9 Score: 99.3673 bits (246), Expect = 1.343e-20 Identity = 158/694 (22.77%), Postives = 271/694 (39.05%), Query Frame = 3
Query: 294 QVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI--CNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNA-VLRIYEGFNVKPQS---ELCGTDSAIPSYF-SSSNFIRVRFLTDITSKGARGFQIV 2348
V L+F F +E ++ +C D ++I S P +GR+CG+ +PH + S +N ++++F +D + + GF+A ++ + S C +H +G +SP YP P + C++ S S R++L F+ F L QQ C +++EI + + + R CG + N+ H L+++ V SS+ GF+ F+ LY + I GT G I SP L P+ N + +Q+ F +++ ++ D C L I F+ + P V CG L R+ + L F +GF + + +++ G T +S G C +T + SP + N Y N C + +S + + ++F ED SC D L + R+ + + R CG +PG + + + S+ L F S+ NG GF ASY S CG + + G + SP+YP Y + C WH+ S + T FQ++G +CS L + G + S LCGT ++P+ ++ N + VRF++D +++G GF+++
Sbjct: 1676 HVTLSFTDFELEMINSNCSHDAVEILDGDNS------------DAPSVGRYCGND---VPHPVTSFSNALVVNFVTDASVT----------RKGFRATYT-------------ASTSGCGGNLHME---SGAFNSPNYPDAYPPNIECVWTIIS-SPGNRLQLSFVLFEL-QQSTGCNNDYLEI----REGNSTGALVGRFCGNSLPSNYTSLIGH-VLWVKFVS----------------DSSVSGAGFRATFSH---------LYG--NDITGTS------------GQIASP------LYPRTYPVNADYRWTITVSGDSYIQIRFLDIDIEDLYD--CYYDQLKI----FDGPNV---------HALPLGVFCG---LLLPGLVRSSGSTVTLEFKSDTVIGGRGFLVEWTAIQNSGPLPT-ISPGACGGALMPGDT--PRFLFSPGWPNEYEPNQECTW--VIRSPDSTVELNLLFLDIED-----------EASCLYDSLVI-----RDGETNLSPELARLCGRQLPGSIHTTRDSM--FLRFTSDYSINGRGFNASY---------SKGCGGLLHTDR--GVLSSPNYPQNYKPNQDCSWHVMVTSGFRVSVTFLTPFQVQGYGTACSTGDYLELRNGPDADAPSLGGRLCGT--SVPAVTQTTDNHLHVRFVSDASNEG-NGFKLI 2221 HSP 10 Score: 88.5817 bits (218), Expect = 2.621e-17 Identity = 155/717 (21.62%), Postives = 256/717 (35.70%), Query Frame = 3
Query: 210 GILLSPNWPG--KYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYI--EVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
G PN PG +Y V +V ++ + + F +F +E S +C D+L I+ +Y +LG++CG + + FS N+ + + + DH+ G T W S +L + G+I SP YPG P +C + L I F +L + C +++EI + L D+ NR C ++ ++ +Y+ + + GF I +T S Y +EG +ISP K C Y E V LNFT++ L C+ Y+ + E LI +Y T P +L N+L + S + V GF+ Y +SG+ G I +P + + YP N C++ ++ L F+ F + C+ DY+ V + + L R+CGT +P +L S QK + + F ++A GF A Y + CG ++ + G I SP +P Y C W++ +V+P L+FT+F +E +C+ + IY+ + L CG S PS S+ N + + F++D +S GF
Sbjct: 484 GTFSYPNTPGHDQYDHMVSCAWVIRTDADKILRVTFPYFELE-HSTTCSFDFLQIHDGESASAY--------------MLGKYCGTNAP--------------AELFSSHNSLYFWFRSDHIINSG-----------GFTVSWTSQAPVCGGHLTNP----YGDIRSPGYPGNYPPNRDCYWTIDVGPGLL-ITFAFGTLSLEHHPD-CNYDYLEIRDG-LLPEDA--LLNRYCSTGSPAPLQTTGPGAWIHFH----SDYV------------ISDQGFHITYTTSPTDPGCGGTYT------------------DTEGILISPNWPNNYAHNKQCVYLI----RVARSETVLLNFTHMELEPHS--GCEFDYVEVRDGLAETDPLIGKY---CGSTLPAPILSSYNHLWIRFKSDSSV-------------SHAGFRAVYEISCGGTLSGS-------------------GQIRTPLHPDAYPHNKKCEWVINQAEGYVVTLNFLTFDVEDSA------------GCYFDYVEVRDGATSSSPLLG-----RFCGTQVPPMLQSTQKQM--YIVFNTDASVTNHGFTAEYASAIQ------GCGDTLTDPT--GTITSPGHPTDYPHGANCTWYI-SVAPGNIIRLSFTTFNLE-YHTNCNYDYVEIYDNGTALTGNLLGRYCGR-SVPPSLTSTDNLMTILFVSD-SSLSTEGF 1045 HSP 11 Score: 79.7221 bits (195), Expect = 1.580e-14 Identity = 173/807 (21.44%), Postives = 287/807 (35.56%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHN--IVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYP-GLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG-IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPV-------------------------IILKLNFTQ--PVRKE-------QQGFKLSYRFLKDFGISGTMVSRGRC--------------------------------------HYRYQSEETGYRGL------------------INSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGF-LQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD--ITSKGAR 2333
G + SPN+P YP + + + +V L +E SC DY+++ I+ ++ + P L RFCG +P + S N + + F +D + + GF A++S S + C ++ G++T SP Y G ++LNC + ++ + + + ID + + C +++E +L ++ + R+CG S +L++ S+ ++GFK+ + FSD C Q+ + G + SPG + +P C + + L FTY + E +C ++IY+ + +I +Y + P + G N L + + + V I N+ Q P E +G L F DF I S G+C H R+QS ET +G + SP Y + YP++S+C Y A +I L F FQ + A+ T +D VK +G + N CG +IPG + L L F S+ N GFLA Y I VF+ GS S T H Y ++ C +H+ VS L F SF +E +S +C+ + +Y+G N + CGT+ P+ ++SN + + F TD +T +G R
Sbjct: 2472 GTISSPNYPNLYPHNRVCRWRITVPQGRRVTLTINDLRLEDHG-SCSFDYVEV------------INGLVANSPRLQRFCGS----VPAGTQVKSSGNTMTVVFATDSS----------VSNGGFNADYS------------SDEAAVCGGVLDTPGNFT----SPDYGIGNYSNSLNCEWLIQNPNHVNSSIVVLIDDMHLEHHQTCEWDYLEF----RLGDENAELLGRICGQTVPEVPIVVSTPQLWVHF----------------RSDESVVDLGFKVTYYFSD-------------------CG-GYQTGEG--GTVSSPGYPDSYPSPSRCVWLL----EAPEGHTITLTFTYFEVEEHS--QCSWDSVTIYNGASAGSPIIGQY---CGHSSPGTIQSGSNKLTVVFLADHSVSRGGFIATWTTDSSGCGGTIHADSGTIKSPNYPQNFPANVECSWTIIAHEGNHLEMGFASDFQIPD---SSGQCQSSYIKVWSGPRAENDALLATGCGSTAPPAVIAPYNVIHARFQSTETVGKGFSSSFYTRCGANFSASAGRVVSPNYPDLYPASSNCDYLINAGDQTVIFLTFRTFQ----IEAESTCVYDG--------------VKIYSGTSVNGNPVATLCGNTIPGPFTTFGPML---LNFYSDFIINDNGFLAEYTAIPCGGVFNGTSGSVSSPT---------HAISNYHHNINCTYHI-TVSNNRIIELKFNSFHLEASS-TCAFDYVALYDGPNTLAPLLGKFCGTE-LPPTLKTTSNDLFIVFKTDSSVTGEGWR 3148 HSP 12 Score: 75.0998 bits (183), Expect = 3.888e-13 Identity = 155/684 (22.66%), Postives = 252/684 (36.84%), Query Frame = 3
Query: 96 ILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTG------GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNF-EHFNIEGLSFSCEK-DYLDIYIEVKSYKNRINISNILFHEPVLG-RFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIH-ANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI-CNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTN-KTERYCGTSIPGILVSQQKSLGFTLT--FKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP-GRYSSDLICEW 2102
I R +FL F S + SI + YS G G+L SPN+P Y + + M + +V + F F ++G +C DYL++ +N + P LG R CG S +P + +N + + F SD + + + GFK F +H ++C I +G G I+SP YP P ++C++ + ++LDF DF + + + C +++EI + ++SD+ D +LCG S+ + +YLR S+ + GFK K++ + Y Q G I SPG ++ C ++ G + L+++ LNL C + Y+ I + + L + + P V G ++ + S V GF LSY S C + G I+SP Y N YP N C++ + L + + H SC DY+ V NG + + + +R+CG+ G +Q KS G T+T F +++ + GF A Y + CG + + G SP Y G YS+ L CEW
Sbjct: 2079 IHTTRDSMFLRFTS-----DYSINGRGFNASYSKGCGGLLHTDRGVLSSPNYPQNYKPNQDCSWHVMVTSGFRVSVTFLTPFQVQGYGTACSTGDYLEL-------RNGPDAD-----APSLGGRLCGTS---VPAVTQTTDNHLHVRFVSDASNEGN----------GFKLIFE-------------AHSTACGGTIELKDGDPPGYITSPDYPSNYPQNIDCVWIIMVPNG-ESVQLDFEDFYI-EPNTQCAYDYLEI--RDGVNSDT-DLIAKLCGNTKPSTQHSTASAMYLRFRT----------------DQSVTHKGFKAKYSIAV----CGGTYIGQ------------------SGTIRSPGYPDSNYPDNSNCEWYLEG----PTGHYLTLSYSALNL--QSSTGCVNDYVEIREYNASGRLLGRH----CGMSLPLSVDTGDSFAYVKFVSDGSV-------------NAPGFSLSYE-----------ASVEEC----GGDLNAASGTISSPNYPNLYPHNRVCRWRITVPQGRRVTLTINDLRLED------------HGSCSFDYVEVI------NGLVANSPRLQRFCGSVPAG---TQVKSSGNTMTVVFATDSSVSNGGFNADYSSDEAAV-----CGGVLDTP---GNFTSPDYGIGNYSNSLNCEW 2609 HSP 13 Score: 70.4774 bits (171), Expect = 9.969e-12 Identity = 166/754 (22.02%), Postives = 274/754 (36.34%), Query Frame = 3
Query: 141 TKIANSSIENIFYEHFYSN-KMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY---TGEISSPTYP-GLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYF-FMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIY---SVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTS--IPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPS-YFSSSNFIRVRFLTDITSKGAR-GFQIVWT 2354
T+ + FY +N + G ++SPN+P YP Y+ + + L F F IE S +C D + IY N + CG++ IP + ++L+F+SD F N + +Y A I G + +G +SSPT+ +NC Y + S I L F F+L + C ++V + + P + + CG + ++ N L++ SS+ G++ + R+ P C + +S G SP I+ K NY + + + + L+F L M C+ Y+ IY SV++ + T T P + N+L + S V +GF +Y + C Y + T I SP+Y N YP+ +SC++ A + E ++++ FQ +YL + + + G + ++CG+ IP S +++ LTF+S+A +G GF +YQ +V+ YGY+ SP +P Y ++ C L A P+ I L F +F +E + SCS L I G + CG S +PS F N + + F +D +S AR GF+I WT
Sbjct: 2913 TETVGKGFSSSFYTRCGANFSASAGRVVSPNYPDLYPASSNCDYLINAGDQTVIFLTFRTFQIEAES-TCVYDGVKIYSGTSVNGNPV------------ATLCGNT---IPGPFTTFG-PMLLNFYSD---------------------FIINDNGFLAEYTA----------IPCGGVFNGTSGSVSSPTHAISNYHHNINCTYHI-TVSNNRIIELKFNSFHL-EASSTCAFDYVALYDGPNTLAP---LLGKFCGTELPPTLKTTSNDLFIVFKT----------------DSSVTGEGWRASY--------------RETLGPEQGCGGYLTAS---SGMFGSPDIDYNG---KYENYMDCLWTITVSSNKAINLSFLTFELEGMSSSVCRYDYVQIYDGDSVNYPL------VGTFCGTTVPAPFVSSSNFLTVHFVSDGSVSF-------------RGFNATYSAVDRL-----------CGGIYNATST--PQTITSPYYPNAYPAFTSCRWVLDAPAQETVKIMVQQFQLQSSQSCS------------SNYLEMKDWPVGDYG-----QAHKFCGSDSHIPD-FYSYDRTM--HLTFQSDAFMSGNGFSLTYQVAGCSRVYEQS----------YGYLKSPGWPATYPHNIDCTIVLRA--PQNSSISLFFDNFDLE-SHPSCSYDFLEIRNGSTASAPLLGKYCG--STLPSPIFPRINELYLHFQSDFSS--ARDGFEITWT 3508 HSP 14 Score: 64.3142 bits (155), Expect = 7.153e-10 Identity = 66/250 (26.40%), Postives = 108/250 (43.20%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEM--CPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQ-FFSSHNRLYL 950
G L SP WP YP ++ V +N + L F++F++E SC D+L+I +N S P+LG++CG +L P I + N + L F SD FS +D GF+ W SS L +GS+T SP +PG + +C ++ R+ S R+ + FN D+ C ++++ + P S+ CG + N F +S +R+++
Sbjct: 3407 GYLKSPGWPATYPHNIDCTIVLRAPQNSSISLFFDNFDLESHP-SCSYDFLEI-------RNGSTAS-----APLLGKYCGSTL---PSPIFPRINELYLHFQSD----FSSARD------GFEIT------------WTSSPQGCGGTLYGDHGSFT----SPDFPGTYANGTHCEWDIRAPSG----RVVTVSFNQIAIDDPGDCQNNYLKLYDGPDA---SSPPVGPYCGAETNIAPFRASSHRVFI 3607 HSP 15 Score: 62.7734 bits (151), Expect = 2.217e-9 Identity = 60/250 (24.00%), Postives = 100/250 (40.00%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVK--PQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G + SP + YP N C A N I L F F + H SC D+L + R +YCG+++P + + L L F+S+ GF ++ + CG + +G SP +PG Y++ CEW + A P R + ++F I+ C N L++Y+G + P CG ++ I + +SS+ + + F GF++ W+
Sbjct: 3407 GYLKSPGWPATYPHNIDCTIVLRAPQNSSISLFFDNFDL------------ESHPSCSYDFLEI-----RNGSTASAPLLGKYCGSTLPSPIFPRINEL--YLHFQSDFSSARDGFEITWTSSPQ------GCGGTLYGD--HGSFTSPDFPGTYANGTHCEWDIRA--PSGRVVTVSFNQIAID-DPGDCQNNYLKLYDGPDASSPPVGPYCGAETNIAPFRASSHRVFIVFHAQSVVL-PSGFRLTWS 3625 HSP 16 Score: 51.9878 bits (123), Expect = 3.986e-6 Identity = 55/220 (25.00%), Postives = 91/220 (41.36%), Query Frame = 3
Query: 114 DLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILL-------SPN--WPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFS-CEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIY 743
DLF++F + + + + E + GG L SP+ + GKY + ++ S N+ ++L+F F +EG+S S C DY+ IY + +N P++G FCG + +P VS +N + + F SD + F GF A +S Y A+S + I+SP YP P+ +C +
Sbjct: 3131 DLFIVFKTDSSVTGEGWRASYRETLGPEQGCGGYLTASSGMFGSPDIDYNGKYENYMDCLWTITVSSNKAINLSFLTFELEGMSSSVCRYDYVQIYD-----GDSVNY-------PLVGTFCGTT---VPAPFVSSSNFLTVHFVSDGSVSFR----------GFNATYSAVDRLCGGIYNATSTPQT--------------ITSPYYPNAYPAFTSCRW 3311
BLAST of Cubilin vs. Ensembl Cavefish
Match: cubn (cubilin [Source:NCBI gene;Acc:103044622]) HSP 1 Score: 122.479 bits (306), Expect = 1.255e-27 Identity = 170/734 (23.16%), Postives = 281/734 (38.28%), Query Frame = 3
Query: 207 GGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFI-DFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYT-NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYH-DVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQ-CGSNISSTSYYGYIHSP--HYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKS-CSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNG 2381
GG + SP +P YP R V++ E + L F +F +E S C D + IY + P++G++CGHS P I S +N + + F +D + + + GF A + ++ S C IHA+ +G I SP YP P+ + C + + + + F DF + C ++++ + P+ ++D+ A CG + +N ++ R S + +G +F T C + S G ++SP A C+Y N + V+ L F + E + DG +K Y P LCG N + +T+ P++ LNF GF Y + G+ G G ++SP + + Y N +C Y +N +I L K S+H + +C DY+ + + L ++CGT +P L + L + FK+++ G G+ ASY + + +Q CG ++++S G SP Y G+Y + + C W + VS + L+F +F++EG S S C ++IY+G N CGT P + SSSNF+ V F++D S RGF ++ V RL G
Sbjct: 2705 GGTVSSPGYPDSYPSPSRCVWLLEAPEGHTITLTFTYFEVEEHS-QCSWDSVTIYNGASA------------GSPIIGQYCGHSS---PGTIQSGSNKLTVVFLADHS----------VSRGGFIATW-------------TTDSSGCGGTIHAD---SGTIKSPNYPQNFPANVECSWTIIAHEG-NHLEMGFASDFQIPDSSGQCQSSYIKVWSGPRAENDALLATG--CGSTAPPAVIAPYNVIHARF-------------------QSTETVGKGFSSSFY------------------TRCGANFSA---SAGRVVSPNYPDLYPASSNCDYLI----NAGDQTVIFLTFRTFQI-EAESTCVYDG--------------VKIYSGTSVNGNPVATLCG-NTIPGPFTTFGPML---LNFYSDFIINDNGFLAEYTAIPCGGVF-----------------NGTSGSVSSPTHAISNYHHNINCTYHITVSNNRIIEL-------------KFNSFHLEASSTCAFDYVALYDGPNTLAPLLG-----KFCGTELPPTLKTTSNDL--FIVFKTDSSVTGEGWRASY----RETLGPEQGCGGYLTASS--GMFGSPDIDYNGKYENYMDCLWTI-TVSSNKAINLSFLTFELEGMSSSVCRYDYVQIYDGDSVNYPLVGTFCGTTVPAP-FVSSSNFLTVHFVSD-GSVSFRGFNATYSAV-DRLCGG 3283 HSP 2 Score: 120.168 bits (300), Expect = 5.943e-27 Identity = 177/769 (23.02%), Postives = 289/769 (37.58%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVK--PQSELCGTDSAIPSYF-SSSNFIRVRFLTDITSKGARGFQIVWTRV-----IPRLSNGSCPG 2393
L ++F S I+ ++Y++ ++G G SP++P KYP + V+ S V + F+IE SC+ D L++Y P L + C P + S N + + F SD+ ++ GF A+ W + +I + +GEI SP YP P+ ++C + + RI +F D ++ + C ++V++ + P DS+ ++CG +S+ N +Y+R R+ + H GFK +F+ C I + D G I SP + CN+ + + V L+FT L EM + C + I + RY CG N + + TS + +++ NF ++GF+ +Y + T G H G NSP Y + YP N C + + ++L F++F+ + C+ DYL + E G L R+CG S+P S + + F S++ +G GF R FS G++I+ TS G I SP YP Y + W + VS + F IE C L+I++G NV P CG +P SS + + + F +D T G RGF + WT + +P +S G+C G
Sbjct: 1380 LHVIFNSDLSISLPGFRMLWYQNGCGGDLSGPSGNFTSPDYPNKYPDNRECVWYIQTSPGSSVTITIHEFDIESHP-SCDFDLLEVY------------GGPDLSSPRLAQLCTTRPPNNPLQVSSTGNTVTVRFKSDE----------YISGRGFSAS------------WQETQGGCGGPII----APSGEIHSPQYPNNYPNNVDCSWVITVDQG-HRILFNFTDVDI-ESHSSCQWDYVDVHDGP---GDSSPLLAKVCGFSVPAPIYSTQNVIYVRF-----RSDISGNHR-----------GFKAEFS--------------------EACGSTIMADDVG-GAIASPNYPYPYPNNQNCNWIIIA---QEPFNHVTLSFTDFEL-EMINSNCSHDAVEILDGDNSDAPSVGRY-------------CG-NDVPHPVTSFSNALVV--NFVTDASVTRKGFRATY-------TASTSGCGGNLHME--------SGAFNSPNYPDAYPPNIECVWTIISSPGNRLQLSFVLFELQQST------------GCNNDYLEIRE--GNSTGAL----VGRFCGNSLPSNYTSLIGHV-LWVKFVSDSSVSGAGF---------RATFSHLYGNDITGTS--GQIASPLYPRTYPVNADYRWTI-TVSGDSYIQIRFLDIDIEDL-YDCYYDQLKIFDGPNVHALPLGVFCGL--LLPGLVRSSGSTVTLEFKSD-TVIGGRGFLVEWTAIQNSGPLPTISPGACGG 1997 HSP 3 Score: 117.857 bits (294), Expect = 3.567e-26 Identity = 162/717 (22.59%), Postives = 278/717 (38.77%), Query Frame = 3
Query: 204 TGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRL---VVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKY-LIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSN---FIRVRFLTDITSKG 2327
T GIL+SPNWP Y + + VY+ + +E V LNF H +E S CE DY +EV+ + +P++G++CG +L P I+S N + + F SD + + GF+A + + S +G+I +P +P P C + + L+F+ F++ + C ++VE+ + + S+ R CG + S+ ++Y+ + + E Y S++Q G T +D + + + D+ G C I ++PG +++L+FT NL + C Y+ IY + L+ RY CG++ ++ N + IL F +GF +Y L + C Y++ G++ SP Y + YPS C Y + N I L F F+ + +C DY+ + R+ GF + RYC P I++S L + FKS+ GF A + + CG + T+ G SP+YP Y + C WH+ V+ L F F +E +S C L +Y+G N + ++LCG + IP+ +S+ ++++R + I++ G
Sbjct: 718 TEGILISPNWPNNYAHNKQCVYLIRVARSETVLLNFTHMELEPHS-GCEFDY----VEVRD--------GLAETDPLIGKYCGSTL---PAPILSSYNHLWIRFKSDSSVSHA----------GFRAVYEISCGGTL--------------------SGSGQIRTPLHPDAYPHNKKCEWVINQAEGYV-VTLNFLTFDV-EDSAGCYFDYVEVRDGA---TSSSPLLGRFCGTQVPPMLQSTQKQMYIVFNTDASVTNHGFTAE------YASAIQGCGD----TLTDPTGTITSPGHPTDYPHGANCTWYIS---------VAPG------------------------NIIRLSFTTFNLEYHTN--CNYDYVEIYDNGTALTGNLLGRY-------------CGRSVPPSLTSTDNLMTIL---FVSDSSLSTEGFSANYVSLN---------ATTDCSAEYRTP----TGVLTSPNYPSNYPSTRECVYKIIVEINMQIMLNFTDFEL------------EGGSNCPFDYVEI-----RDGGFETSPLIGRYCSNQPPPIVISHSNML--WILFKSDFTATARGFSAHWDGTQT------GCGGTL--TTSVGSFTSPNYPLPYHPNAECYWHIK-VNAGSSIQLNFEDFHLE-SSTDCYYDYLAVYDGNSTNDRQLAKLCG--NQIPNPITSTRDQMYVKLRTDSIISAGG 1278 HSP 4 Score: 104.375 bits (259), Expect = 3.858e-22 Identity = 178/762 (23.36%), Postives = 286/762 (37.53%), Query Frame = 3
Query: 153 NSSIENIFYEHFYSNKMTG---------GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTE--CDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSA-IPSYFSSS-NFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG 2393
++S+ N + Y++ + G G + SP P YP + + + L+F FN+E +C DY++IY + + LGR+CG S +P ++ S +N++ + F SD + + GF AN+ A++ S+ + + TG ++SP YP PST C+Y+ E + +I L+F DF L + CP ++VEI R G + + L GR +P I + S++ I FK FT + + H GT+ C + +S G SP P Y+ + ++ + +QLNF +L D C YL++Y + + + LCG N + TS + +KL + GF SY SG +++ G+I S + N YP N+ C + I F F P SC DY+ + E + R+CG + P + SL + F S+ + PGF + + + CG ++S S G SP YP +Y + C W++ SP +T F IE + SC +L +Y G ++ ++LC T P SS+ N + VRF +D G RGF W + G C G
Sbjct: 920 DASVTNHGFTAEYASAIQGCGDTLTDPTGTITSPGHPTDYPHGANCTWYISVAPGNIIRLSFTTFNLE-YHTNCNYDYVEIYDNGTALTGNL-----------LGRYCGRS---VPPSLTSTDNLMTILFVSDSS----------LSTEGFSANY--------VSLNATTDCSAEYR------TPTGVLTSPNYPSNYPSTRECVYKIIVEINM-QIMLNFTDFEL-EGGSNCPFDYVEI---------------RDGGFETS---------------PLIGRYCSNQPPPIVISHSNMLWILFKSDFTATAR--------GFSAHWDGTQTGCGGTLTTS---VGSFTSPNY-PLPYHPNAECYWHIKVNAGSS---IQLNFEDFHLESSTD--CYYDYLAVYDGNSTNDRQLAK-------------LCG-NQIPNPITSTRDQMYVKLRTDSIISA--GGFVASYTS----NCSGIVIANKT------------SGVIESQNFPNNYPFNARCSWTIQTTMGNTINYTFTAFDLEGLSP-----------SCIYDYMLLYNGPNEEAPLIG-----RFCGNTPPPAGATTSSSL--HVIFNSDLSISLPGF--------RMLWYQNGCGGDLSGPS--GNFTSPDYPNKYPDNRECVWYIQ-TSPGSSVTITIHEFDIE-SHPSCDFDLLEVYGGPDLSSPRLAQLCTTRPPNNPLQVSSTGNTVTVRFKSDEYISG-RGFSASWQE-----TQGGCGG 1525 HSP 5 Score: 103.99 bits (258), Expect = 5.323e-22 Identity = 172/720 (23.89%), Postives = 281/720 (39.03%), Query Frame = 3
Query: 201 MTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSK-NNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFR-SESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRL---VVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNIS--STSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD--ITSKG 2327
M G SPN+P YP ++ V+ + S ++ L+F F ++ S C DYL+I N + L +GRFCG+SL P N S +V+ + F SD + + GF+A FS Y IT +G+I+SP YP P +N Y + + S + I++ F+D ++ + C + ++I + P + + CG+ SS + + L V+ GR +++E +++QN G PL + PG C + D ++ SPG + C + +T V+LN +L++ + + C L I + + R LCG+ +T+R+ + L FT +GF SY S+G C ++ RG+++SP Y Y N C + S + + F+ P ++ Y + DYL + + L R CGTS+P V+Q + F S+A G GF ++ S CG I GYI SP YP Y ++ C W + V E L F F IE ++ C+ L I +G N ++LCG ++ + S+++ + +RF TD +T KG
Sbjct: 1762 MESGAFNSPNYPDAYPPNIECVWTIISSPGNRLQLSFVLFELQ-QSTGCNNDYLEI--------REGNSTGAL-----VGRFCGNSL---PSNYTSLIGHVLWVKFVSDSS----------VSGAGFRATFSHLYGNDIT-------------------GTSGQIASPLYPRTYP--VNADYRWTITVSGDSYIQIRFLDIDIEDLYD-CYYDQLKIFDGPNVHALPLGV---FCGLLLPGLVRSSGSTVTLEFKSDTVIGGRGFLVE-------WTAIQNSG------------PLPTIS------PGA-CGGALMPGDTPR-FLFSPGWPNEYEPNQECTWVIRSPDST-----VELNLLFLDIED--EASCLYDSLVIRDGETNLSPELAR-------------LCGRQLPGSIHTTRDSMF---LRFTSDYSINGRGFNASY-------------SKG-CGGLLHTD----RGVLSSPNYPQNYKPNQDCSWHVMVTSGFRVSVTFLT-------PFQVQGYGTACST--GDYLELRNGPDADAPSLG----GRLCGTSVPA--VTQTTDNHLHVRFVSDASNEGNGFKLIFE------AHSTACGGTIELKDGDPPGYITSPDYPSNYPQNIDCVW-IIMVPNGESVQLDFEDFYIEPNTQ-CAYDYLEIRDGVNSDTDLIAKLCG-NTKPSTQHSTASAMYLRFRTDQSVTHKG 2337 HSP 6 Score: 101.679 bits (252), Expect = 3.102e-21 Identity = 171/704 (24.29%), Postives = 254/704 (36.08%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFID-FNLYQQDEMCPV-EFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNF-YPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF--NVKPQSELCGTDSAIPSYFSSSNFIRVRFLTD 2312
L SP WP +Y + +V S + V LN +IE + SC D L I N+S P L R CG L P +I + + + L F SD +S N GF A++S C L+H + G +SSP YP +C + S R+ + F+ F + C +++E+ N P D+D+ RLCG ++ N L++R V A S + GFK+ F + H I+++ D GYI SP C + M N E VQL+F + + +C YL I LI + + TKP T + + L F +GFK Y GT + G G I SP Y + YP NS+C++ + + L + C DY+ + E +G L R+CG S+P + V S + + F S+ N PGF SY+ ++CG ++++ S G I SP+YP Y + +C W + V R LT ++E SCS + + G N CG+ A SS N + V F TD
Sbjct: 2008 LFSPGWPNEYEPNQECTWVIR-SPDSTVELNLLFLDIEDEA-SCLYDSLVIR------DGETNLS------PELARLCGRQL---PGSIHTTRDSMFLRFTSD----YSIN------GRGFNASYS----------------KGCGGLLHTD---RGVLSSPNYPQNYKPNQDCSWHVMVTSGF-RVSVTFLTPFQVQGYGTACSTGDYLELRNGP--DADAPSLGGRLCGTSVPAVTQTTDNHLHVRFVSDA----------------SNEGNGFKLIF---------------EAHSTACGGTIELKDGDP-PGYITSPDYPSNYPQNIDCVWIIM----VPNGESVQLDFEDFYI--EPNTQCAYDYLEIRDGVNSDTDLIAK---LCGNTKPS-------------TQHSTASAMYLRFRTDQSVTHKGFKAKYSIAV---CGGTYI--------------GQSGTIRSPGYPDSNYPDNSNCEWYLEGPTGHYLTLSYSALNLQSST------------GCVNDYVEIREY--NASGRL----LGRHCGMSLP-LSVDTGDSFAY-VKFVSDGSVNAPGFSLSYE------ASVEECGGDLNAAS--GTISSPNYPNLYPHNRVCRWRI-TVPQGRRVTLTINDLRLE-DHGSCSFDYVEVINGLVANSPRLQRFCGSVPAGTQVKSSGNTMTVVFATD 2561 HSP 7 Score: 100.908 bits (250), Expect = 4.985e-21 Identity = 179/755 (23.71%), Postives = 283/755 (37.48%), Query Frame = 3
Query: 96 ILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTG-GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
IL+ L++ F S + ++++ + YE ++G G + +P P YP + + +V +E V LNF F++E S C DY+++ S P+LGRFCG +P + S + K +N D + GF A + AS+ L TG I+SP +P P NC + + S + IRL F FNL + C ++VEI + + + + R CG S+ N + + V SSL GF S Y LNA T+C + ++ G + SP + + C Y + N Q + LNFT L + C Y+ I FE LI RY P V+ N L I+ K +FT R GF + + G GT+ + G SP Y Y N+ C + + I+L F F L S D C+ DYL V + + + CG IP + S + + L ++++ + GF+ASY + C + + G I S ++P Y + C W + TFT+F +EG S SC + +Y G N + CG ++ P+ ++S+ + V F +D+ S GF+++W
Sbjct: 794 ILSSYNHLWIRFKSDSSVSHAGFRAV-YEISCGGTLSGSGQIRTPLHPDAYPHNKKCEWVINQAEGYVVTLNFLTFDVED-SAGCYFDYVEVRDGATS------------SSPLLGRFCGTQ---VPPMLQS----------TQKQMYIVFNTDASVTNHGFTAEY------------ASAIQGCGDTLTDP----TGTITSPGHPTDYPHGANCTW-YISVAPGNIIRLSFTTFNL-EYHTNCNYDYVEIYDNGT--ALTGNLLGRYCGRSVPPSLTSTDNLMTILFVS----------------DSSLSTEGF------SANYVSLNAT---------TDCSAEYRTP---TGVLTSPNYPSNYPSTRECVYKIIVEINMQ----IMLNFTDFELEGGSN--CPFDYVEIRDGGFETSPLIGRY---CSNQPPPIVISHSNMLW---------ILFKSDFTATAR----GFSAHWDGTQT-GCGGTLTTS--------------VGSFTSPNYPLPYHPNAECYWHIKVNAGSSIQLNFEDFH--------LESSTD----CYYDYLAV-----YDGNSTNDRQLAKLCGNQIPNPITSTRDQMYVKL--RTDSIISAGGFVASY---------TSNCSGIVIANKTSGVIESQNFPNNYPFNARCSWTIQTTM-GNTINYTFTAFDLEGLSPSCIYDYMLLYNGPNEEAPLIGRFCG-NTPPPAGATTSSSLHVIFNSDL-SISLPGFRMLW 1399 HSP 8 Score: 99.7525 bits (247), Expect = 1.203e-20 Identity = 163/718 (22.70%), Postives = 266/718 (37.05%), Query Frame = 3
Query: 210 GILLSPNWP-GKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIIN-----QPQLDSDSNDADNRLCG-IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI-CNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFL-TDITSKG 2327
G + SP +P YP + + G + L++ N++ S C DY +E++ Y N S L LGR CG SL P ++ + ++ + F SD + FS Y + + + +S G ISSP YP L P C + R+ L D L + C ++VE+IN P+L R CG + Q SS N + VV A SS+ N GF ++ SD+ + + + G SP + + + C + ++ + VV ++ +L + C+ YL + + E L+ R +CG+ + P + + + V GFK++Y F D G YQ TG G ++SP Y + YPS S C + A I L F F+ E H C D +T+ + + +YCG S PG + S L T+ F ++ + GF+A++ S CG I + S G I SP+YP + +++ C W + A + + FQI +S C ++ ++++ G + + L CG+ +A P+ + N I RF T+ KG
Sbjct: 2356 GTIRSPGYPDSNYPDNSNCEWYLEGPTGHYLTLSYSALNLQS-STGCVNDY----VEIREY----NASGRL-----LGRHCGMSL---PLSVDTGDSFAYVKFVSDGSVN--------------APGFSLSYEASVEECGGDLNAAS------------GTISSPNYPNLYPHNRVCRWRITVPQG-RRVTLTINDLRL-EDHGSCSFDYVEVINGLVANSPRL--------QRFCGSVPAGTQVKSSGNTM---TVVFA-------------TDSSVSNGGFNADYS-SDEAAVCGGVLD-------------------TPGNFTSPDYGIGNYSNSLNCEWLIQNPNHVNSSIVVLIDDMHLEHHQ----TCEWDYLE-FRLGDENAELLGR-------------ICGQTVPEVPIVVSTPQLWVHFRSDESVVD--LGFKVTYYF-SDCG-------------GYQ---TGEGGTVSSPGYPDSYPSPSRCVWLLEAPEGHTITLTFTYFEVEE------------HSQCSWDSVTIYNGASAGSPIIG-----QYCGHSSPGTIQSGSNKL--TVVFLADHSVSRGGFIATW------TTDSSGCGGTIHADS--GTIKSPNYPQNFPANVECSWTIIAHEGNHLEMGFASDFQIPDSSGQCQSSYIKVWSGPRAENDALLATGCGS-TAPPAVIAPYNVIHARFQSTETVGKG 2919 HSP 9 Score: 99.3673 bits (246), Expect = 1.688e-20 Identity = 158/694 (22.77%), Postives = 271/694 (39.05%), Query Frame = 3
Query: 294 QVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI--CNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNA-VLRIYEGFNVKPQS---ELCGTDSAIPSYF-SSSNFIRVRFLTDITSKGARGFQIV 2348
V L+F F +E ++ +C D ++I S P +GR+CG+ +PH + S +N ++++F +D + + GF+A ++ + S C +H +G +SP YP P + C++ S S R++L F+ F L QQ C +++EI + + + R CG + N+ H L+++ V SS+ GF+ F+ LY + I GT G I SP L P+ N + +Q+ F +++ ++ D C L I F+ + P V CG L R+ + L F +GF + + +++ G T +S G C +T + SP + N Y N C + +S + + ++F ED SC D L + R+ + + R CG +PG + + + S+ L F S+ NG GF ASY S CG + + G + SP+YP Y + C WH+ S + T FQ++G +CS L + G + S LCGT ++P+ ++ N + VRF++D +++G GF+++
Sbjct: 1676 HVTLSFTDFELEMINSNCSHDAVEILDGDNS------------DAPSVGRYCGND---VPHPVTSFSNALVVNFVTDASVT----------RKGFRATYT-------------ASTSGCGGNLHME---SGAFNSPNYPDAYPPNIECVWTIIS-SPGNRLQLSFVLFEL-QQSTGCNNDYLEI----REGNSTGALVGRFCGNSLPSNYTSLIGH-VLWVKFVS----------------DSSVSGAGFRATFSH---------LYG--NDITGTS------------GQIASP------LYPRTYPVNADYRWTITVSGDSYIQIRFLDIDIEDLYD--CYYDQLKI----FDGPNV---------HALPLGVFCG---LLLPGLVRSSGSTVTLEFKSDTVIGGRGFLVEWTAIQNSGPLPT-ISPGACGGALMPGDTPR--FLFSPGWPNEYEPNQECTW--VIRSPDSTVELNLLFLDIED-----------EASCLYDSLVI-----RDGETNLSPELARLCGRQLPGSIHTTRDSM--FLRFTSDYSINGRGFNASY---------SKGCGGLLHTDR--GVLSSPNYPQNYKPNQDCSWHVMVTSGFRVSVTFLTPFQVQGYGTACSTGDYLELRNGPDADAPSLGGRLCGT--SVPAVTQTTDNHLHVRFVSDASNEG-NGFKLI 2221 HSP 10 Score: 88.5817 bits (218), Expect = 3.265e-17 Identity = 155/717 (21.62%), Postives = 256/717 (35.70%), Query Frame = 3
Query: 210 GILLSPNWPG--KYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYI--EVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
G PN PG +Y V +V ++ + + F +F +E S +C D+L I+ +Y +LG++CG + + FS N+ + + + DH+ G T W S +L + G+I SP YPG P +C + L I F +L + C +++EI + L D+ NR C ++ ++ +Y+ + + GF I +T S Y +EG +ISP K C Y E V LNFT++ L C+ Y+ + E LI +Y T P +L N+L + S + V GF+ Y +SG+ G I +P + + YP N C++ ++ L F+ F + C+ DY+ V + + L R+CGT +P +L S QK + + F ++A GF A Y + CG ++ + G I SP +P Y C W++ +V+P L+FT+F +E +C+ + IY+ + L CG S PS S+ N + + F++D +S GF
Sbjct: 484 GTFSYPNTPGHDQYDHMVSCAWVIRTDADKILRVTFPYFELE-HSTTCSFDFLQIHDGESASAY--------------MLGKYCGTNAP--------------AELFSSHNSLYFWFRSDHIINSG-----------GFTVSWTSQAPVCGGHLTNP----YGDIRSPGYPGNYPPNRDCYWTIDVGPGLL-ITFAFGTLSLEHHPD-CNYDYLEIRDG-LLPEDA--LLNRYCSTGSPAPLQTTGPGAWIHF----HSDYV------------ISDQGFHITYTTSPTDPGCGGTYT------------------DTEGILISPNWPNNYAHNKQCVYLI----RVARSETVLLNFTHMELEPHS--GCEFDYVEVRDGLAETDPLIGKY---CGSTLPAPILSSYNHLWIRFKSDSSV-------------SHAGFRAVYEISCGGTLSGS-------------------GQIRTPLHPDAYPHNKKCEWVINQAEGYVVTLNFLTFDVEDSA------------GCYFDYVEVRDGATSSSPLLG-----RFCGTQVPPMLQSTQKQM--YIVFNTDASVTNHGFTAEYASAIQ------GCGDTLTDPT--GTITSPGHPTDYPHGANCTWYI-SVAPGNIIRLSFTTFNLE-YHTNCNYDYVEIYDNGTALTGNLLGRYCGR-SVPPSLTSTDNLMTILFVSD-SSLSTEGF 1045 HSP 11 Score: 79.337 bits (194), Expect = 1.763e-14 Identity = 173/807 (21.44%), Postives = 287/807 (35.56%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHN--IVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYP-GLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG-IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPV-------------------------IILKLNFTQ--PVRKE-------QQGFKLSYRFLKDFGISGTMVSRGRC--------------------------------------HYRYQSEETGYRGL------------------INSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGF-LQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD--ITSKGAR 2333
G + SPN+P YP + + + +V L +E SC DY+++ I+ ++ + P L RFCG +P + S N + + F +D + + GF A++S S + C ++ G++T SP Y G ++LNC + ++ + + + ID + + C +++E +L ++ + R+CG S +L++ S+ ++GFK+ + FSD C Q+ + G + SPG + +P C + + L FTY + E +C ++IY+ + +I +Y + P + G N L + + + V I N+ Q P E +G L F DF I S G+C H R+QS ET +G + SP Y + YP++S+C Y A +I L F FQ + A+ T +D VK +G + N CG +IPG + L L F S+ N GFLA Y I VF+ GS S T H Y ++ C +H+ VS L F SF +E +S +C+ + +Y+G N + CGT+ P+ ++SN + + F TD +T +G R
Sbjct: 2472 GTISSPNYPNLYPHNRVCRWRITVPQGRRVTLTINDLRLEDHG-SCSFDYVEV------------INGLVANSPRLQRFCGS----VPAGTQVKSSGNTMTVVFATDSS----------VSNGGFNADYS------------SDEAAVCGGVLDTPGNFT----SPDYGIGNYSNSLNCEWLIQNPNHVNSSIVVLIDDMHLEHHQTCEWDYLEF----RLGDENAELLGRICGQTVPEVPIVVSTPQLWVHF----------------RSDESVVDLGFKVTYYFSD-------------------CG-GYQTGEG--GTVSSPGYPDSYPSPSRCVWLL----EAPEGHTITLTFTYFEVEEHS--QCSWDSVTIYNGASAGSPIIGQY---CGHSSPGTIQSGSNKLTVVFLADHSVSRGGFIATWTTDSSGCGGTIHADSGTIKSPNYPQNFPANVECSWTIIAHEGNHLEMGFASDFQIPD---SSGQCQSSYIKVWSGPRAENDALLATGCGSTAPPAVIAPYNVIHARFQSTETVGKGFSSSFYTRCGANFSASAGRVVSPNYPDLYPASSNCDYLINAGDQTVIFLTFRTFQ----IEAESTCVYDG--------------VKIYSGTSVNGNPVATLCGNTIPGPFTTFGPML---LNFYSDFIINDNGFLAEYTAIPCGGVFNGTSGSVSSPT---------HAISNYHHNINCTYHI-TVSNNRIIELKFNSFHLEASS-TCAFDYVALYDGPNTLAPLLGKFCGTELP-PTLKTTSNDLFIVFKTDSSVTGEGWR 3148 HSP 12 Score: 74.7146 bits (182), Expect = 5.451e-13 Identity = 155/684 (22.66%), Postives = 252/684 (36.84%), Query Frame = 3
Query: 96 ILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTG------GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNF-EHFNIEGLSFSCEK-DYLDIYIEVKSYKNRINISNILFHEPVLG-RFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIH-ANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI-CNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTN-KTERYCGTSIPGILVSQQKSLGFTLT--FKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP-GRYSSDLICEW 2102
I R +FL F S + SI + YS G G+L SPN+P Y + + M + +V + F F ++G +C DYL++ +N + P LG R CG S +P + +N + + F SD + + + GFK F +H ++C I +G G I+SP YP P ++C++ + ++LDF DF + + + C +++EI + ++SD+ D +LCG S+ + +YLR S+ + GFK K++ + Y Q G I SPG ++ C ++ G + L+++ LNL C + Y+ I + + L + + P V G ++ + S V GF LSY S C + G I+SP Y N YP N C++ + L + + H SC DY+ V NG + + + +R+CG+ G +Q KS G T+T F +++ + GF A Y + CG + + G SP Y G YS+ L CEW
Sbjct: 2079 IHTTRDSMFLRFTS-----DYSINGRGFNASYSKGCGGLLHTDRGVLSSPNYPQNYKPNQDCSWHVMVTSGFRVSVTFLTPFQVQGYGTACSTGDYLEL-------RNGPDAD-----APSLGGRLCGTS---VPAVTQTTDNHLHVRFVSDASNEGN----------GFKLIFE-------------AHSTACGGTIELKDGDPPGYITSPDYPSNYPQNIDCVWIIMVPNG-ESVQLDFEDFYI-EPNTQCAYDYLEI--RDGVNSDT-DLIAKLCGNTKPSTQHSTASAMYLRFRT----------------DQSVTHKGFKAKYSIAV----CGGTYIGQ------------------SGTIRSPGYPDSNYPDNSNCEWYLEG----PTGHYLTLSYSALNL--QSSTGCVNDYVEIREYNASGRLLGRH----CGMSLPLSVDTGDSFAYVKFVSDGSV-------------NAPGFSLSYE-----------ASVEEC----GGDLNAASGTISSPNYPNLYPHNRVCRWRITVPQGRRVTLTINDLRLED------------HGSCSFDYVEVI------NGLVANSPRLQRFCGSVPAG---TQVKSSGNTMTVVFATDSSVSNGGFNADYSSDEAAV-----CGGVLDTP---GNFTSPDYGIGNYSNSLNCEW 2609 HSP 13 Score: 61.6178 bits (148), Expect = 4.780e-9 Identity = 164/754 (21.75%), Postives = 272/754 (36.07%), Query Frame = 3
Query: 141 TKIANSSIENIFYEHFYSN-KMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSY---TGEISSPTYP-GLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYF-FMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIY---SVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTS--IPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPS-YFSSSNFIRVRFLTDITSKGAR-GFQIVWT 2354
T+ + FY +N + G ++SPN+P YP Y+ + + L F F IE S +C D + IY N + CG++ IP + ++L+F+SD F N + +Y A I G + +G +SSPT+ +NC Y + S I L F F+L + C ++V + + P + + CG + ++ N L++ SS+ G++ + R+ P C + +S G SP I+ K NY + + + + L+F L M C+ Y+ IY SV++ + T T P + N+L + S V +GF +Y + C Y + T I SP+Y N YP+ +SC++ A + E ++++ FQ +YL + + + G + ++CG+ IP S +++ LTF+S+A +G GF +YQ + VF Y++S +P Y ++ C L A P+ I L F +F +E + SCS L I G + CG S +PS F N + + F +D +S AR GF+I WT
Sbjct: 2913 TETVGKGFSSSFYTRCGANFSASAGRVVSPNYPDLYPASSNCDYLINAGDQTVIFLTFRTFQIEAES-TCVYDGVKIYSGTSVNGNPV------------ATLCGNT---IPGPFTTFG-PMLLNFYSD---------------------FIINDNGFLAEYTA----------IPCGGVFNGTSGSVSSPTHAISNYHHNINCTYHI-TVSNNRIIELKFNSFHL-EASSTCAFDYVALYDGPNTLAP---LLGKFCGTELPPTLKTTSNDLFIVFKT----------------DSSVTGEGWRASY--------------RETLGPEQGCGGYLTAS---SGMFGSPDIDYNG---KYENYMDCLWTITVSSNKAINLSFLTFELEGMSSSVCRYDYVQIYDGDSVNYPL------VGTFCGTTVPAPFVSSSNFLTVHFVSDGSVSF-------------RGFNATYSAVDRL-----------CGGIYNATST--PQTITSPYYPNAYPAFTSCRWVLDAPAQETVKIMVQQFQLQSSQSCS------------SNYLEMKDWPVGDYG-----QAHKFCGSDSHIPD-FYSYDRTM--HLTFQSDAFMSGNGFSLTYQVLYHNIVFV--------------YVYSTGWPATYPHNIDCTIVLRA--PQNSSISLFFDNFDLE-SHPSCSYDFLEIRNGSTASAPLLGKYCG--STLPSPIFPRINELYLHFQSDFSS--ARDGFEITWT 3504 HSP 14 Score: 58.151 bits (139), Expect = 5.344e-8 Identity = 63/248 (25.40%), Postives = 106/248 (42.74%), Query Frame = 3
Query: 216 LLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEM--CPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQ-FFSSHNRLYL 950
+ S WP YP ++ V +N + L F++F++E SC D+L+I +N S P+LG++CG +L P I + N + L F SD FS +D GF+ W SS L +GS+T SP +PG + +C ++ R+ S R+ + FN D+ C ++++ + P S+ CG + N F +S +R+++
Sbjct: 3405 VYSTGWPATYPHNIDCTIVLRAPQNSSISLFFDNFDLESHP-SCSYDFLEI-------RNGSTAS-----APLLGKYCGSTL---PSPIFPRINELYLHFQSD----FSSARD------GFEIT------------WTSSPQGCGGTLYGDHGSFT----SPDFPGTYANGTHCEWDIRAPSG----RVVTVSFNQIAIDDPGDCQNNYLKLYDGPDA---SSPPVGPYCGAETNIAPFRASSHRVFI 3603 HSP 15 Score: 57.3806 bits (137), Expect = 8.719e-8 Identity = 57/239 (23.85%), Postives = 95/239 (39.75%), Query Frame = 3
Query: 1647 YPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVK--PQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
YP N C A N I L F F + H SC D+L + R +YCG+++P + + L L F+S+ GF ++ + CG + +G SP +PG Y++ CEW + A P R + ++F I+ C N L++Y+G + P CG ++ I + +SS+ + + F GF++ W+
Sbjct: 3414 YPHNIDCTIVLRAPQNSSISLFFDNFDL------------ESHPSCSYDFLEI-----RNGSTASAPLLGKYCGSTLPSPIFPRINEL--YLHFQSDFSSARDGFEITWTSSPQ------GCGGTLYGD--HGSFTSPDFPGTYANGTHCEWDIRA--PSGRVVTVSFNQIAID-DPGDCQNNYLKLYDGPDASSPPVGPYCGAETNIAPFRASSHRVFIVFHAQSVVL-PSGFRLTWS 3621 HSP 16 Score: 51.9878 bits (123), Expect = 4.640e-6 Identity = 55/220 (25.00%), Postives = 91/220 (41.36%), Query Frame = 3
Query: 114 DLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILL-------SPN--WPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFS-CEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIY 743
DLF++F + + + + E + GG L SP+ + GKY + ++ S N+ ++L+F F +EG+S S C DY+ IY + +N P++G FCG + +P VS +N + + F SD + F GF A +S Y A+S + I+SP YP P+ +C +
Sbjct: 3131 DLFIVFKTDSSVTGEGWRASYRETLGPEQGCGGYLTASSGMFGSPDIDYNGKYENYMDCLWTITVSSNKAINLSFLTFELEGMSSSVCRYDYVQIYD-----GDSVNY-------PLVGTFCGTT---VPAPFVSSSNFLTVHFVSDGSVSFR----------GFNATYSAVDRLCGGIYNATSTPQT--------------ITSPYYPNAYPAFTSCRW 3311
BLAST of Cubilin vs. Ensembl Cavefish
Match: pcolce2a (procollagen C-endopeptidase enhancer 2a [Source:ZFIN;Acc:ZDB-GENE-070705-25]) HSP 1 Score: 89.7373 bits (221), Expect = 1.880e-18 Identity = 69/251 (27.49%), Postives = 111/251 (44.22%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGR-YSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
TGY G I S + YP+N+ C + ++ L+F V D C DY+ V E G + + R+CGTS PG LV+ + + S+A+ G GFLA+Y ++ +V + CG + G + +P++P + Y + + C WH+ V+P+ + I LTF F +E C + +Y G + CG P + S V+F++D+ S A GF
Sbjct: 39 TGYSGFIGSSGHPGVYPANTKCVWRITVPQGRVVSLLFRVMDLENDG------------LCRYDYVDVYE------GHVSGQRLGRFCGTSRPGPLVTSGNKMQVVMV--SDANTAGSGFLAAYAAVRPNEVGNRYCGGLLKKP---GSLKTPNWPDKDYPAGVTCSWHI--VAPQNQIIELTFEKFDVE-RDNYCRYDHMAVYNGGETSDSRRIGRFCGDSPPAPIHSEGSQLF-VQFVSDL-SLTADGF 261
BLAST of Cubilin vs. Ensembl Cavefish
Match: bmp1a (bone morphogenetic protein 1 [Source:NCBI gene;Acc:103024888]) HSP 1 Score: 82.0333 bits (201), Expect = 2.123e-15 Identity = 143/649 (22.03%), Postives = 238/649 (36.67%), Query Frame = 3
Query: 198 KMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITK------------------------YWASSHHSSC-----FYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDK-----------YEPLNA-------------LYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIK 1985
K G + SPN+P Y + V+ ++ V L F+ F IE SC DYL EV+ + + P+LGRFCG+ P +I + +N + + F SD + + K GF ANF FK + ++ Y ++ SC ++ NGS I+SP +P P NCI++ + T RI L F F + +++C +FVE+ + L +DS + CG + S +N + + +++ GFK +F FSDK +E +N L+ + CD + S G I SP + K C + +T +++ F +++ +C ++ IY + RY KP V+ N + + S N V +++GF+ S+ C R ++E ++ F N YP S CQ+ A+ + LIF F+ E+ C DY+ + + ++ + RYCG+ P + S S+ + F+S+ N GF Y K
Sbjct: 429 KKDNGQIQSPNYPDDYRPNKVCVWKITVAQGYHVGLTFQSFEIERHD-SCAYDYL----EVRDGNSE--------NSPLLGRFCGYDK---PDDIKTSSNQLWMKFVSDGS----------VNKAGFAANF-FKEMDECSRPDNGRCEQRCVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNGS----ITSPGWPREYPPNKNCIWQLVA-PTQYRITLLFDVFET-EGNDVCKYDFVEV--RSGLSADSR-LHGKFCGAEKPEAITSQYNNMRIEFKS----------------DNTVSKKGFKAQF-FSDKDECSKENGGCQHECVNTFGSYSCQCRSGFVLHENKHDCKEAGCDHTVNS---VSGTITSPNWPDKYPSKKACTWAL----STTPGHRIKIAFNEIDMEPH--LECAYDHIEIYDGRDGKAPSLGRY---CGSKKPPPVMSSGNKMFIRFFSDNSV-------------QKKGFEASH--------------SAECGGRLKAEVKTKDLYSHAQFGDNNYPGASDCQWVISAEKGYGVELIFQTFEIEEEA------------DCGYDYMELFDGAD-----TKSPRLGRYCGSGPPEEIYSAGDSI--VIKFRSDDTINKKGFHVRYTSTK 966 HSP 2 Score: 72.7886 bits (177), Expect = 1.390e-12 Identity = 133/601 (22.13%), Postives = 217/601 (36.11%), Query Frame = 3
Query: 681 TGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPV--IILKLNFTQPV---------RKEQQGFKL--SYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASY----------------QFIKKRKVFSDQC----------------GSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQS--ELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
+G SSP +P + ++CI+ S + +I L+F +LY+ +C + VEI + + R CG K S+ +RL++ ++SS +G FS YE + ++D+ G I SP K+C + + + T+ + + C YL + + E L+ R+ KPD + N L + S V NF + + R EQ+ SY+ D G R C T G I SP + YP N +C + A + I L+F VF+T + DV C D++ V R + ++CG P + SQ ++ + FKS+ + GF A + + + +S QC G + + S G I SP++P +Y S C W L + +P R + F +E C+ + IY+G + K S CG+ P SS N + +RF +D S +GF+
Sbjct: 319 SGNFSSPGFPNGYSAYMHCIWRI-SVTPGEKIILNFTSMDLYRS-HLCWYDHVEIRDGYWRKAP---LKGRFCGDKLPEPIISTDSRLWIE------------------FRSSSNWVGK----GFSAVYEAICGGEVKKDN-----------------GQIQSPNYPDDYRPNKVC------VWKITVAQGYHVGLTFQSFEIERHDSCAYDYLEVRDGNSENSPLLGRF---CGYDKPDDIKTSSNQLWMKFVSDGSVNKAGFAANFFKEMDECSRPDNGRCEQRCVNTLGSYKCACDPGYELAADKRS-CEAACGGFITKLNGSITSPGWPREYPPNKNCIWQLVAPTQYRITLLFDVFETEGN---------DV---CKYDFVEV-----RSGLSADSRLHGKFCGAEKPEAITSQYNNM--RIEFKSDNTVSKKGFKAQFFSDKDECSKENGGCQHECVNTFGSYSCQCRSGFVLHENKHDCKEAGCDHTVNSVSGTITSPNWPDKYPSKKACTWAL-STTPGHRIKIAFNEIDME-PHLECAYDHIEIYDGRDGKAPSLGRYCGSKKP-PPVMSSGNKMFIRFFSD-NSVQKKGFE 842 HSP 3 Score: 61.6178 bits (148), Expect = 4.066e-9 Identity = 73/271 (26.94%), Postives = 119/271 (43.91%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVI---PRLSNGSCPGFQCLNS 2411
G +SP + N Y + C + E I L F TS D+ + HL C D++ + R+ + + R+CG +P ++S L + F+S+++ G GF A Y+ I CG + + G I SP+YP Y + +C W + V+ LTF SF+IE SC+ L + +G N CG D +SSN + ++F++D + A GF + + + R NG C +C+N+
Sbjct: 320 GNFSSPGFPNGYSAYMHCIWRISVTPGEKIILNF----TSMDL-------YRSHL-CWYDHVEI-----RDGYWRKAPLKGRFCGDKLPEPIISTDSRL--WIEFRSSSNWVGKGFSAVYEAI---------CGGEVKKDN--GQIQSPNYPDDYRPNKVCVWKI-TVAQGYHVGLTFQSFEIE-RHDSCAYDYLEVRDGNSENSPLLGRFCGYDKP-DDIKTSSNQLWMKFVSDGSVNKA-GFAANFFKEMDECSRPDNGRCEQ-RCVNT 555
BLAST of Cubilin vs. Ensembl Cavefish
Match: tll1 (tolloid-like 1 [Source:NCBI gene;Acc:474335]) HSP 1 Score: 81.6481 bits (200), Expect = 3.136e-15 Identity = 165/754 (21.88%), Postives = 274/754 (36.34%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYE---PLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAP--KICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVII-----LKLNFTQPVRKEQQGFKLSYRFLKD-------------FGISGTMVSRGRCHY-----RYQSEETGYRGLINSPFYT-------NFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYG--YIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G SP +P YP V+ + E++ LNF ++ S C DY IEV+ R P+LGRFCG D +P ++S + + ++F S N +GK GF A + +TK +G+I SP YP + C++ + S + L F F + + D C +++E+ + S+S+ R CG S+ N L+++ V ++ GF F F ++ E P N C+ + ++ S PG LAP K C G+ + N + + P K+ Q + Y +S + + + V D L G KY T VI +++ F ++GFK + KD G+ V + R + ++ +E I+SP T + YPS C +D A I++ F F+ + H C D+L + ++ L R CG+ IP L+S + L F S+A GF A++ S +CG + + + Y H+ Y CEW + A + LTFT+F++E C + +Y+G + CG+ +S+ + + + F +D T +GF I +T
Sbjct: 375 GNFSSPGYPNGYPSYTHCVWRISVTPGEKIVLNFTTMDLYKSSL-CWYDY----IEVRDGYWR--------KAPLLGRFCG---DKVPEMLISTESRMWIEFRSSSNW---------VGK-GFAAVYEAICGGDVTKD-------------------SGQIQSPNYPDDYRPSKECVWRI-TVSEGYNVGLSFQAFEIERHDS-CAYDYLEVRDGL---SESSPLIGRFCGYDKPEDIRSTSNTLWMKFVS----------------DGTVNKAGFAANF-FKEEDECVKPDNG-----------GCEQRCVNTLGSFKCACDPGYE---LAPDKKSCEAACGGLLSKLNGTITTPGWP-KEYPPNKNCVWQVVAPTQYRISMQFEVCKYDFVEVRSGLSSDSKLHG----KYCGTEVPEVITSQYNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECINTIGSYVCQCRNGFVLHENKHDCKEAECEHTIHSPSGTISSPNWPDKYPSRKECTWDITATPGHRIKITFNEFEIEQ------------HQECAYDHLEAFDGESDKSSILS-----RLCGSKIPEPLISTGNKM--YLRFISDASVQRKGFQATH---------STECGGRLKAEARQKNLYSHAQFGDNNYPGHTDCEWLITAEAGYS-IELTFTTFEVE-EEADCGYDYIELYDGHDTSAHKLGRFCGS-GPREELYSAGDTVLIHFHSDDTIS-KKGFHIRYT 1010 HSP 2 Score: 67.781 bits (164), Expect = 4.839e-11 Identity = 122/600 (20.33%), Postives = 214/600 (35.67%), Query Frame = 3
Query: 93 LILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMT--GGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITK-----------------------YWASSHHSSCFYLIHANGS-YTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDK-----------YEPLNA-------------LYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDV 1742
++++ +++ F S + + YE +T G + SPN+P Y V+ SE V L+F+ F IE SC DYL++ R +S P++GRFCG+ P +I S +N + + F SD + K GF ANF + +E + Y + SC S G I++P +P P NC+++ + T RI + F E+C +FVE+ + L SDS + CG + S +N + + +++ GFK F FSDK +E +N L+ + EC+ I S G I SP + K C + + +++ F + + ++ C +L + + ++ R LCG + ++ N + L F +++GF+ ++ C R ++E ++ F N YP ++ C++ A++ I L F F+ E+
Sbjct: 448 MLISTESRMWIEFRSSSNWVGKGFAAV-YEAICGGDVTKDSGQIQSPNYPDDYRPSKECVWRITVSEGYNVGLSFQAFEIERHD-SCAYDYLEV---------RDGLSE---SSPLIGRFCGYDK---PEDIRSTSNTLWMKFVSDGT----------VNKAGFAANFFKEEDECVKPDNGGCEQRCVNTLGSFKCACDPGYELAPDKKSCEAACGGLLSKLNGTITTPGWPKEYPPNKNCVWQVVA-PTQYRISMQF---------EVCKYDFVEV--RSGLSSDSK-LHGKYCGTEVPEVITSQYNNMRIEFKS----------------DNTVSKKGFKAHF-FSDKDECSKDNGGCQHECINTIGSYVCQCRNGFVLHENKHDCKEAECEHTIHS---PSGTISSPNWPDKYPSRKECTWDITATPGHR----IKITFNEFEIEQHQE--CAYDHLEAFDGESDKSSILSR-------------LCGSKIPEPLISTGNK---MYLRFISDASVQRKGFQATHST--------------ECGGRLKAEARQKNLYSHAQFGDNNYPGHTDCEWLITAEAGYSIELTFTTFEVEEEA 951
BLAST of Cubilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007253.1 (pep scaffold:Pmarinus_7.0:GL476910:54360:144194:-1 gene:ENSPMAG00000006538.1 transcript:ENSPMAT00000007253.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 95.1301 bits (235), Expect = 4.016e-20 Identity = 168/757 (22.19%), Postives = 285/757 (37.65%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKF--TFSDKYEPLNALYN----------RQDHIPGTECDIKIQSSDQS--------EGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYS-VSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVII--LKLNFTQPVRKEQQ--------------GFKLSYR---FLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKP--QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G SP +P YP V+ + E++ LNF ++ F + D YIEV+ P+LGR CG D +P +VS ++ + ++F S N + + +++++ + C ++ G+I SP YP + C+++ + L F F + + D C +++E+ + D+DS+ R CG + SS N+L+++ V SS+ GF F + P N R PG E +S + + G + SPG + K C + + + + L F + L E D C+ Y+ I S +S E K K T + PD + N L+ + S N V K++F + Q + R L + G VS C ++ S E G+I+SP + + YP+ C ++ A ++L F F+ + H C D+L V + + L R+CG+ P ++S + L F S+A GF A + + K+ +D + S + +G +YPG+ L C+W + A LTF +F+IE C + +Y+G++ CG+ Y SS + I +RF +D T G +GF +T
Sbjct: 223 GNFSSPGFPNGYPSYSHCVWKISVTPGEKITLNFTSLDV----FKSRLCWYD-YIEVRD--------GFWRKAPLLGRVCG---DKLPEPLVSTSSWMWIEFRSSSN--------------------------WVGRGFSAAYEAICGGEVNRE---NGQIQSPNYPDDYRPSKECVWKISVTEGFI-VGLTFQAFEIEKHDN-CAYDYLEVRDG---DNDSSQLIGRYCGYEKPDDIKSSSNKLWMKFVS----------------DSSVNKAGFAANFFKEIDECARPDNGGCEQNCVNTLGSYRCACDPGYELAPDKRSCEAACGGFLNKLNGTMTSPGWPKEYPPNKHCVWQVVAPAQYR----ISLQFEFFEL-EGNDV-CKYDYVEIRSGLSSESKLHGKFCGTEL----PDVITSQNNNLRLEFKSDNTVSKKGFKVHFFSDKDECSQHNGGCQHDCINTLGSYSCQCRNGFMLHENGHDCKEVSTAGCEHKINSAE----GVISSPNWPDKYPNRRECTWEISATPGHRVKLTFSEFEVEQ------------HQECAYDHLEVYDGSSEKAPILG-----RFCGSKKPEAVLSTLNKM--YLRFMSDASVQKRGFQAIHSTVCGGKLRADVAPRELYSHAQFG---DNNYPGQ----LDCDWVITA-EDGYGVELTFLTFEIE-EEADCGYDYMELYDGYSADALRLGRFCGSGPPEEVY-SSGDSIMIRFHSDDTI-GKKGFHARYT 869 HSP 2 Score: 84.3445 bits (207), Expect = 7.663e-17 Identity = 101/401 (25.19%), Postives = 167/401 (41.65%), Query Frame = 3
Query: 195 NKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHS--------SC----FYLIHANG----------------SYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI-----CNYFFMGIHNTQNMEVVQLN-FTYLNLPE 1289
NK+ G + SP WP +YP + V+ + ++ L FE F +EG C+ DY++I S + + G+FCG L P I S+NN + L+F SD NT + K GFK +F F + +++ H SC +++H NG S G ISSP +P P+ C +E S + R++L F +F + Q E C + +E+ D S A R CG K S+ N++YLR + A ++ S++ G K++ + + +A + ++ +CD I + D GY G+ L +I C Y +M +++ + + ++L F PE
Sbjct: 488 NKLNG-TMTSPGWPKEYPPNKHCVWQVVAPAQYRISLQFEFFELEGNDV-CKYDYVEIR------------SGLSSESKLHGKFCGTEL---PDVITSQNNNLRLEFKSD-NT---------VSKKGFKVHF-FSDKDECSQHNGGCQHDCINTLGSYSCQCRNGFMLHENGHDCKEVSTAGCEHKINSAEGVISSPNWPDKYPNRRECTWEI-SATPGHRVKLTFSEFEVEQHQE-CAYDHLEV-----YDGSSEKAPILGRFCGSKKPEAVLSTLNKMYLRFMSDA----SVQKRGFQAIHSTV--CGGKLRADVAPRELYSHAQFGDNNYPGQLDCDWVITAED---GY----GVELTFLTFEIEEEADCGYDYMELYDGYSADALRLGRFCGSGPPE 840 HSP 3 Score: 70.8626 bits (172), Expect = 1.214e-12 Identity = 83/274 (30.29%), Postives = 122/274 (44.53%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDV-PAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI--LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVI---PRLSNGSCPGFQCLNS 2411
G +SP + N YPS S C + E I L F TS DV ++L C DY+ V + R+ L R CG +P LVS + + F+S+++ G GF A+Y+ I CG ++ + G I SP+YP Y C W +S E FI LTF +F+IE +C+ L + +G N Q CG + SSSN + ++F++D +S GF + + I R NG C C+N+
Sbjct: 223 GNFSSPGFPNGYPSYSHCVWKISVTPGEKITLNF----TSLDVFKSRL---------CWYDYIEVRDGFWRKAPLLG-----RVCGDKLPEPLVSTSSWM--WIEFRSSSNWVGRGFSAAYEAI---------CGGEVNREN--GQIQSPNYPDDYRPSKECVW---KISVTEGFIVGLTFQAFEIE-KHDNCAYDYLEVRDGDNDSSQLIGRYCGYEKP-DDIKSSSNKLWMKFVSD-SSVNKAGFAANFFKEIDECARPDNGGCEQ-NCVNT 458
BLAST of Cubilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008741.1 (pep scaffold:Pmarinus_7.0:GL478849:6130:19306:1 gene:ENSPMAG00000007913.1 transcript:ENSPMAT00000008741.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 70.0922 bits (170), Expect = 2.111e-13 Identity = 67/253 (26.48%), Postives = 106/253 (41.90%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKS----------------CSNAVLRIYEGF-NVKPQ-SELCGTDSAIPSYFSSSNFIRVRFLTDIT 2318
G I+SP + N Y C++ A + + + ++F D+ +C DY+ + R+ + RYCG PG+LVS +L + F+S+ G GF Y+ K SD C N ++ S G + SP +P +YS L C + + A P+ +L FT F +EG S+ C L +++G NV P CG + SS+ + +RF TD
Sbjct: 12 GNISSPGFPNEYLPRQHCEWVLRAPGPD--QRLSVIFNPHFDLEGH---------NCRFDYVEL-----RDGDGPSADIIGRYCGMVAPGLLVSSGSAL--FVRFESDYAHQGAGFSLHYEIHKSG---SDDCSWNFTAPS--GVLSSPGFPDKYSHYLECTYTVWA-GPRRDLVLRFTHFHVEGVSRGPPGAGPNPHLAGGVTDCPYDRLEVWDGLSNVGPLIGHYCGRRAPW-VLRSSTGVLSLRFFTDAA 239
BLAST of Cubilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008025.1 (pep scaffold:Pmarinus_7.0:GL476353:328552:336612:1 gene:ENSPMAG00000007257.1 transcript:ENSPMAT00000008025.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 70.4774 bits (171), Expect = 9.879e-13 Identity = 68/263 (25.86%), Postives = 114/263 (43.35%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIF--IVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTER-YCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKS--CSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIP 2366
+G G SP Y + YP+ + C + + + L F ++ + E C DY+ V + + +ER + GT +P + + L + F S+ + GFLA Y +D+C + T+ G +HSP YPG Y + C W L AV P R L+F F +E + + C + +++G S L CG+ P+ S+S+ + + TD +S+ RGF + +T V+P
Sbjct: 141 SGPSGSFASPAYPSHYPNGADCVWALGHSAASVTALAFRDLLLEEGE--------------GCGFDYVAVYAGGEEA----GGDGSERCFNGTDLPTFVSPPGRRL--LVVFHSDYNIGARGFLAEYH--------TDECQRTL--TALQGDVHSPRYPGPYPGGVRCRW-LLAVPPPLRLRLSFRDFHLEESDERGHCGYDQVALFDGETENENSSLGRFCGSRMP-PATTSTSSKLLITMHTD-SSEALRGFSLSYTAVVP 370
BLAST of Cubilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009500.1 (pep scaffold:Pmarinus_7.0:GL481336:529:7336:-1 gene:ENSPMAG00000008591.1 transcript:ENSPMAT00000009500.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.151 bits (139), Expect = 4.374e-9 Identity = 48/164 (29.27%), Postives = 75/164 (45.73%), Query Frame = 3
Query: 2010 CGSNISSTSY-YGYIHSPHYPGRYSSDLICEWHLHAVSPKERFIL---TFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQ--CLNSGHCISKNLTCNKVFNCGSYVNNSG 2483
CGS + S G IHSP +P Y L C W + A P + +FT F++EG S+ C+ L + G CG+ + P + S + + ++F +D ++ G+ GF++ + V L CP Q C N G C+ + CN CG + G
Sbjct: 2 CGSMMEEMSGPSGVIHSPGWPTAYPGSLNCSWFIRA-QPGHVITIRGGSFTGFEMEG-SEGCTADWLMLGPGSRGAHDYRACGS-ALPPPFISPRDHVWIKFHSDASASGS-GFELRY--VTSLLQATQCPDDQLRCAN-GRCVLRTWECNGQDECGDGSDERG 158
BLAST of Cubilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001622.1 (pep scaffold:Pmarinus_7.0:GL490886:345:4014:-1 gene:ENSPMAG00000001462.1 transcript:ENSPMAT00000001622.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 55.0694 bits (131), Expect = 1.001e-8 Identity = 43/153 (28.10%), Postives = 72/153 (47.06%), Query Frame = 3
Query: 2010 CGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTS-FQIEGTSKSCSNAVLRIYEGFNVKPQSE---LCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLS---NGSCPGFQCLNSGHCIS--KNLTC 2441
CG + S GY+ SP YP Y C W L A SP+++ ++ F F +E SC +++++ + K + CGT + P SS + V+F++D T++GA GF + + P + N + P + + GH + N C
Sbjct: 1 CG-GVVVVSLPGYLTSPGYPEDYPPHQTCSWQLRAPSPEQKLLINFNPHFDME--KNSCRFDYVQVWDDGDEKSGDDSGKFCGTVAPAP-ILSSGPTLHVKFVSDYTTQGA-GFSLRYELYKPGVDCSRNFTAPSGRIASPGHPLGYPPNAAC 148
BLAST of Cubilin vs. Ensembl Nematostella
Match: EDO41783 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3J5]) HSP 1 Score: 75.8702 bits (185), Expect = 5.128e-14 Identity = 66/238 (27.73%), Postives = 105/238 (44.12%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQS--ELCGTDSAIPSYF-SSSNFIRVRFLTDIT 2318
G SP Y + YP C++ E I L F VF K TS++ C D++ V + RE +N R+CGT +P + S L + FKS+ ++ PGF A V+ +CG I +G I SP YP Y S C W + R + F +F +E + C L++++G + S + CG + IP S+S+++ ++F +D +
Sbjct: 219 GAFTSPGYPSPYPLGRHCEWRISVTPGERIVLNFTVFHL------KKTSFN----KCKNDFVEVRDGHGRE-----SNLIGRFCGTRVPPSIWSTGSRL--WIKFKSDGVESRPGFKA---------VYETRCGGPIRKA--HGTIQSPKYPSWYPSSKECVWTIALPGKGSRVGMRFVAFDVE-DHEQCHYDYLQLFDGQDEWAPSIGKFCGKE--IPGEVRSNSSYLTIKFKSDAS 425 HSP 2 Score: 68.5514 bits (166), Expect = 1.068e-11 Identity = 151/737 (20.49%), Postives = 266/737 (36.09%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFS-CEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYN--------RQDHIPGTECDIKIQSS-DQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQY--DFFAKSNEMIRLIFI-----VFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFL--------QTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYG--YIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDS--AIPSYFSSSNFIRVRFLTDITSK 2324
G SP +P YP + + E++ LNF F+++ SF+ C+ D+ +EV+ R SN++ GRFCG +P +I S + + + F SD + GFKA + + I K +H G I SP YP PS+ C++ +R+ + F+ F++ + E C +++++ + + + + CG + + S+ + L ++ A N Y S N L N + H G C+ G I SP + K C + G + + + L F L + C+ Y+ + ++ RY CG K T +P ++ + F + ++GF Y +D +G C + + YR F +P SC+ D + + LI V+Q +D K+T H+ + +L + E + ++ Q R CG ++P S+ + + F S++ GF A Y + CG+N+++ S Y H + Y + C W L A + FI L F F IE CS + I +G + + CG+ + S+ N + + F+TD+T++
Sbjct: 219 GAFTSPGYPSPYPLGRHCEWRISVTPGERIVLNFTVFHLKKTSFNKCKNDF----VEVRDGHGRE--SNLI------GRFCGTR---VPPSIWSTGSRLWIKFKSDGVES----------RPGFKAVYETRCGGPIRK----AH---------------GTIQSPKYPSWYPSSKECVWTIALPGKGSRVGMRFVAFDV-EDHEQCHYDYLQLFDG---QDEWAPSIGKFCGKEIPGEVRSNSSYLTIKFKSDASIN------KPGFYLSFFSERNECNNNNGGCSQICQNTLGNYKCACYPGYELHSDGKNCEAACGGVLSNGNGTITSPSYPASYPKNKRCLWRITG----PSGQRISLKFNDFRLEGNGNGVCRYDYVEVRD---HENKILGRY-------------CGS---KNPETVTSPSNVMWVEFRSDHTQSRRGFSAKYYADED----ECRERKGGCQHICVNTIGSYRCTCKPGFV--LHPDQHSCKEASDCGSTVTSLTGLIMSPNFPGVYQHKKDCTWKITVTPGSHVELNFRFLQIEEAKECRYDYVEVFSGTGHQAESLGRICGNNLPSPFRSRAHKM--LIKFHSDSLIAKRGFKARY---------TAHCGANLNAVSQKRIFYSHPAYGDDNYGPKMKCNWTLTA---RNGFIKLRFKEFDIE-KEAYCSYDYVNIRDGNSTSSPLLGKQCGSSGKKGPLEFVSTGNKMYIEFVTDVTNQ 857 HSP 3 Score: 64.3142 bits (155), Expect = 1.822e-10 Identity = 104/449 (23.16%), Postives = 159/449 (35.41%), Query Frame = 3
Query: 1116 ECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLK--YSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDF-FAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLAS---------------------------------YQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ-----SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
EC +Q + G SPG + C + + E + LNFT +L + KC++ ++ + LI R+ CG +S SR L + F + + GFK Y RC + G I SP Y ++YPS+ C + + + F+ F + H CH DYL ++ ++ + + ++CG IPG + S L T+ FKS+A N PGF S Y+ K CG +S+ + G I SP YP Y + C W + S +R L F F++EG N V R Y+ V+ CG+ + + S SN + V F +D T + RGF
Sbjct: 209 ECGRTLQ---EPSGAFTSPGYPSPYPLGRHCEWRI----SVTPGERIVLNFTVFHLKKTSFNKCKNDFVEVRDGHGRESNLIGRF-------------CGTRVPPSIWSTGSR-----LWIKFKSDGVESRPGFKAVYET--------------RCGGPIRKAH----GTIQSPKYPSWYPSSKECVWTIALPGKGSRVGMRFVAFDVED------------HEQCHYDYL---QLFDGQDEWAPS--IGKFCGKEIPGEVRSNSSYL--TIKFKSDASINKPGFYLSFFSERNECNNNNGGCSQICQNTLGNYKCACYPGYELHSDGKNCEAACGGVLSNGN--GTITSPSYPASYPKNKRCLWRITGPS-GQRISLKFNDFRLEGN----GNGVCR-YDYVEVRDHENKILGRYCGSKNP-ETVTSPSNVMWVEFRSDHT-QSRRGF 585
BLAST of Cubilin vs. Ensembl Nematostella
Match: EDO47760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKX7]) HSP 1 Score: 70.8626 bits (172), Expect = 1.233e-13 Identity = 72/255 (28.24%), Postives = 113/255 (44.31%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILV-SQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQS--ELCGTDSAIPSYFSSS-NFIRVRFLTDITSKGARGFQIVWT 2354
TG RG + SP + + YP++ +C++ + I L T E + + + C D L EI N ++ + +CGT P + S S+ LT S+ G GF A+++ + QCG S+ + G + SP +P Y +++ CEW + V LTF F IE +SK C + I+EG S CGTDS P + ++V+ +D + G GF+ VWT
Sbjct: 8 TGSRGTLTSPNFPSPYPTDVTCEWVIRVGPKQAIEL------TIETIDIEQSK------KCRYDSL---EINDGPNS--KSPELGAFCGTKPPKAAIRSSGNSMYVKLT--SDDGDTGKGFRATWR-------TASQCGGVFSNLT--GTMTSPMFPSNYPANVDCEWIIK-VPITHALTLTFEVFNIERSSK-CKYDSVEIWEGDKKDSPSLGRFCGTDS--PGEIKAQGTTLKVKLHSDESDTG-HGFRAVWT 229 HSP 2 Score: 59.3066 bits (142), Expect = 1.111e-9 Identity = 39/116 (33.62%), Postives = 58/116 (50.00%), Query Frame = 3
Query: 2010 CGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVK-PQ-SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVW 2351
CG ++ + G + SP++P Y +D+ CEW + V PK+ LT + IE SK C L I +G N K P+ CGT + SS N + V+ +D G +GF+ W
Sbjct: 3 CGGRVTGSR--GTLTSPNFPSPYPTDVTCEWVIR-VGPKQAIELTIETIDIE-QSKKCRYDSLEINDGPNSKSPELGAFCGTKPPKAAIRSSGNSMYVKLTSDDGDTG-KGFRATW 113 HSP 3 Score: 53.5286 bits (127), Expect = 9.972e-8 Identity = 64/237 (27.00%), Postives = 93/237 (39.24%), Query Frame = 3
Query: 198 KMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG 902
++TG G L SPN+P YP DV +V + + L E +IE S C D L+I S P LG FCG I S N + + SD D GK GF+A W ++ + + TG ++SP +P P+ ++C + + T A + L F FN+ ++ C + VEI + DS S R CG
Sbjct: 6 RVTGSRGTLTSPNFPSPYPTDVTCEWVIRVGPKQAIELTIETIDIEQ-SKKCRYDSLEINDGPNS------------KSPELGAFCGTKPP--KAAIRSSGNSMYVKLTSD---------DGDTGK-GFRAT------------WRTASQCGGVF-----SNLTGTMTSPMFPSNYPANVDCEWIIKVPITHA-LTLTFEVFNI-ERSSKCKYDSVEIWEGDKKDSPSL---GRFCG 195
BLAST of Cubilin vs. Ensembl Nematostella
Match: EDO41711 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3E6]) HSP 1 Score: 70.0922 bits (170), Expect = 4.147e-13 Identity = 69/280 (24.64%), Postives = 114/280 (40.71%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTER-YCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKV----------------FSDQCGSNISSTSY-------------YGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKP---QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G + +P Y YPSN C + S +RL+F F S DV ++ V+ +G TN + +CG+ IP L+ + T+ FKSN N GFLA ++ + K+ + G + S SY G I SP+YP +Y + + C W + +V R L+F+ F I+ C + I +G + CG + FSS +R++F++D ++ G +GF+ ++
Sbjct: 1 GSLFTPNYPQEYPSNKECTWFISVPSGHNVRLVFYAFDLSSDV-------------------ACSDAVELRDGKSLTNPVKSTFCGSQIPQALIMTSNLM--TVRFKSNYDGNRRGFLAMFETTSESKLLHGPWTHGCKYECLNTYGQHLGGCVCSASYDPSVNNNLQVSGQTGTIKSPNYPAQYPNSISCTWVI-SVKDGNRVKLSFSDFWID-DQHGCYGDYIEIRDGSSGSSPMLGQRYCG-NKGPGDTFSSGAQMRLQFISDDSATG-QGFKATFS 255 HSP 2 Score: 51.6026 bits (122), Expect = 4.590e-7 Identity = 64/271 (23.62%), Postives = 106/271 (39.11%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANF-SFKYNEMITKYWASSHHSSCF--YLIHANG-----SY-------------TGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLV 959
G L +PN+P +YP + + V L F F++ +C +E++ K+ N PV FCG IP ++ +N++ + F S+ + + GF A F + ++++ W C Y H G SY TG I SP YP P++++C + S R++L F DF + Q C +++EI + S R CG K FSS ++ L+ +
Sbjct: 1 GSLFTPNYPQEYPSNKECTWFISVPSGHNVRLVFYAFDLSS-DVACSD-----AVELRDGKSLTN--------PVKSTFCGSQ---IPQALIMTSNLMTVRFKSNYDGN----------RRGFLAMFETTSESKLLHGPWTHGCKYECLNTYGQHLGGCVCSASYDPSVNNNLQVSGQTGTIKSPNYPAQYPNSISCTWVI-SVKDGNRVKLSFSDFWIDDQ-HGCYGDYIEIRDGSS--GSSPMLGQRYCGNKGPGDTFSSGAQMRLQFI 240
BLAST of Cubilin vs. Ensembl Nematostella
Match: EDO45365 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT04]) HSP 1 Score: 64.6994 bits (156), Expect = 8.843e-11 Identity = 59/223 (26.46%), Postives = 90/223 (40.36%), Query Frame = 3
Query: 1590 QSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSA 2258
Q+ TG G ++SP YP SSC Y+ + L F F +P + V++SC + KR G + CG + P +L FKSN GF A Y +K + + N + +P++P Y S++ C+W L+ VS + F L+ SFQIE +S + + Y +VK + C T A
Sbjct: 121 QTNYTGDSGSLSSPGVNGTYPKTSSCLYNIRVPAGRRALLSFSKFDVLGSMPGCSEASVKVYVSCAE---------KRHVGTFCS------CGLAHPLPFDIYSTDECISLEFKSNGIAQASGFTAQYSSAQKNESVASSACRNPAQDVNERNFFTPNWPMNYPSNISCKWSLN-VSGNDLF-LSLMSFQIEASSSCNPESKIDDYVSVSVKGAKQTCQTAVA 326
BLAST of Cubilin vs. Ensembl Nematostella
Match: EDO47778 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL16]) HSP 1 Score: 63.929 bits (154), Expect = 1.300e-10 Identity = 62/248 (25.00%), Postives = 108/248 (43.55%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKS-----CSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKG-ARGF 2339
G +SP + + YP + C ++ A + +++ F+ F E +C D +T ++ E+G +T+ RYCG S P + S+ ++L + F ++ +G GF A Y+ ++ V C S S G + SP Y Y S + C+W + + P+ R L F F I+ S S C + LR + CG + + +SS ++ + F +D G +GF
Sbjct: 43 GSFSSPRFPDLYPMDLQCVWEITAPESLHVKVSFLSFDVEE----------CGKQACECDAVTFLDV--SESG--ETSVIARYCGHSTPNAVYSRGRTL--RVVFSTDEGDSGFGFRAKYEATQRGFV----CSSKPLVISNGGTLASPDYDTTYPSLVECKWIIKS-PPETRIRLKFLKFSIQNCSNSRAQCTCDHLTLRDGNTSSADVIGRYCGNELPM-DLYSSGRYLWLEFSSDENVNGKGKGF 268 HSP 2 Score: 63.1586 bits (152), Expect = 2.351e-10 Identity = 64/254 (25.20%), Postives = 105/254 (41.34%), Query Frame = 3
Query: 207 GGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSF-SCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDF---NLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRL 956
GG SP +P YP D++ V+ E+ V ++F F++E +CE D + +++V V+ R+CGHS P+ + S+ + + F +D+ G GF F KY + SS L+ +NG G ++SP Y PS + C + +S RIRL F+ F N C + + + + ++ S D R CG + +SS L+L
Sbjct: 42 GGSFSSPRFPDLYPMDLQCVWEITAPESLHVKVSFLSFDVEECGKQACECDAV-TFLDVSESG----------ETSVIARYCGHS---TPNAVYSRGRTLRVVFSTDE------------GDSGF--GFRAKYEATQRGFVCSSKP-----LVISNG---GTLASPDYDTTYPSLVECKWIIKSPPE-TRIRLKFLKFSIQNCSNSRAQCTCDHLTLRDG---NTSSADVIGRYCGNELPMDLYSSGRYLWLEF 255
BLAST of Cubilin vs. Ensembl Medaka
Match: cubn (cubilin [Source:NCBI gene;Acc:105353827]) HSP 1 Score: 120.939 bits (302), Expect = 3.605e-27 Identity = 175/767 (22.82%), Postives = 288/767 (37.55%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYEHF--YSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTEC--DIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNV-KPQ-SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPG 2393
+++ F + ++N E ++ + +TG G + SP P YP + + L F FN+E + C DYL++Y + +GR+CG S +P ++ S + L F SD + GF A++ A++ F S TG +SP YP P+ +C ++ E + +I L+F +F+L C +FVEI + +++ + CG + S NRL++R + ++ + D ++ FS PL + P EC +I+I +Q V+L F+ +L + C YL+++ L+ + LCG L S S + + +KL V GF SY + G ++S GR +RG++ SP + N YP+N+ C + A S I FI F D+ A T SC DY+ + + + T YCG + P S TL F++++ F++ +Q + F + CG ++ G SP YP +Y + C W++ S LT F +E + CS VL +Y G ++ PQ ++LC T ++ S+ N + VRF +D G RGF W V G C G
Sbjct: 891 MYIQFRTDASVSNHGFEAVYDSAIEGCGDTLTGPSGTITSPGHPTSYPHGANCTWFISVQPGNLIRLTFNSFNLE-YHYDCNYDYLEVYDNGTVETGK-----------KIGRYCGRS---VPPSLTSSERQLTLLFVSDYSLSLE----------GFSASY--------VSINATTDCGETFT------SPTGFFTSPNYPDYYPNNRDCTFKIIVELNM-QILLNFTNFHLEGFPPSCNFDFVEIRDG---GYETSPLIGKFCGEQKPPALVSHSNRLWVRFHSDSTTSHSGFTAHWDGTQTGCGGTLTTATGGFSSPNYPL-------PYHPNAECYWNIRINHGNQ-----------------------------------VELRFSDFHLESSQ--GCSFDYLAVHDGDSAGAPLLAK-------------LCGTE-LPPSINSSSHQLYIKLRTDSSVNT--GGFLASYNSRCE----GILIS-GR-----------HRGMVESPNFPNTYPANAMCSWTIQASSGNTINYTFIAF----DLEASFT-------SCTYDYIKLYNGPNEQAPLIGT-----YCGQAPP--PASSTTGSALTLVFRTDSSI----FMSGFQMMW----FQNGCGEELTGPG--GSFSSPGYPNKYPENRECIWYI-TTSAGSSITLTIHEFDVE-FHQDCSFDVLEVYGGPDLSAPQLAKLCTTTTSPMQVSSTGNLLTVRFKSDAYVSG-RGFNASWAEV-----QGGCGG 1502 HSP 2 Score: 115.931 bits (289), Expect = 1.223e-25 Identity = 176/732 (24.04%), Postives = 284/732 (38.80%), Query Frame = 3
Query: 207 GGILLSPNWPGKYPQDVRYVYVFMGSEN-EQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYN----EMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG--IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKI--CNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQ---TSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTS-FQIEGTSKSC-SNAVLRIYEGFNVKPQ---SELCGTDSAIPSYF-SSSNFIRVRFLTDITSKGARGFQIV 2348
GG + SP +P YP + + E V L+F F +E + +C D ++I ++ N L P +GRFCG +PH + S ++ ++++F +D + + + GF+A +S + EM+ + +G +SP YP P L C++ RS S R++L F+ F+L Q D C +++EI + + + R CG + N+ S H L+++ V SS GF+ F+ H+ G D+ +S G I SP L P+ N + N + VQ+ F +++ ++ D C +L I+ Y P CG L + R+ + L F +GF L + +++ G S T + G C + + ET + SP + YP N C + +IR V + S D+ Y D +V R+ + CG PG S S+ + F S++ +G GF ASY S CG + G ++SPHYP Y L C W + V+P R +TF S FQI G+ SC S L + G + LCG S PS ++ N I F++D +++ A GF++
Sbjct: 1623 GGAIASPRYPAPYPPNQNCSWFIKAQEPFNHVTLSFTDFELEAIDSNCSHDAVEI----------LDGDNYL--APSIGRFCG---SVVPHPVTSFSSAMVVNFITDVS----------VSRRGFRAVYSASTSSCGGEMVMQ--------------------SGAFNSPNYPDAYPPNLECVWTIRS-SPGNRVQLSFLTFHL-QGDSSCENDYLEI----REGNSTGALVGRFCGSSLPSNYTSVSGH-ILWVKFVS----------------DSSDSGAGFRATFS----------------HLYGI--DVTGES-----GQIASP------LYPRTYPNNAHYRWTINVEGDSYVQIRFLDMDIEDLYD--CYYDHLKIFDGPDVYHY-------------PLGTFCG---LALPHLIRSSGSTVTLLFKTDTVVGGRGFLLEWTAVQNSGPSPT-IPPGACGGQLVAGET--PAFLFSPAWPGQYPPNQECTW--------LIRSPGSVVEFNVLSLDIEGSTPCYFD-------------RMVIRDGATSVSPVIASLCGREPPGSFHSTGDSM--FIHFSSDSQVSGQGFNASY---------SKGCGGFLHVDR--GVLNSPHYPQNYQPGLNCSWFV-MVTPGFRISVTFQSPFQISGSGTSCNSGDFLEVRNGPDASSPLLGERLCG--STPPSLLQTTDNQIYFNFVSDGSTE-ASGFKLT 2198 HSP 3 Score: 112.849 bits (281), Expect = 1.262e-24 Identity = 177/769 (23.02%), Postives = 285/769 (37.06%), Query Frame = 3
Query: 117 LFLMFLSITKIANSSIENIFYEHFYSNKMTG--GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNV--KPQSELCGTDSAIPSYF-SSSNFIRVRFLTDITSKGARGFQIVWTRV-----IPRLSNGSCPG 2393
L L+F + + I S + +++++ ++TG G SP +P KYP++ ++ S + L F++E C D L++Y P L + C + P + S N++ + F SD ++ GF A+ WA C I A +GEI SP YP P+ ++C + + R+ L+F D ++ + C ++V I + P + S+ +CG S+ N +Y+R + R++ GF +F+ C I + D G I SP + C++F I + V L+FT L E D C + I + I R+ CG + + TS + +++ NF V ++GF+ Y G MV + G NSP Y + YP N C + + ++L F+ F D SC DYL + E G L R+CG+S+P S + + F S++ +G GF R FS G +++ S G I SP YP Y ++ W ++ V + F IE C L+I++G +V P CG A+P SS + + + F TD T G RGF + WT V P + G+C G
Sbjct: 1359 LTLVFRTDSSIFMSGFQMMWFQNGCGEELTGPGGSFSSPGYPNKYPENRECIWYITTSAGSSITLTIHEFDVE-FHQDCSFDVLEVY------------GGPDLSAPQLAKLCTTTTS--PMQVSSTGNLLTVRFKSDA----------YVSGRGFNAS------------WAEVQ-GGCGGPITAP---SGEIHSPLYPNSYPANVDCSWVISVDHN-HRVFLNFTDLDI-ELHTNCTWDYVAIHDGPSI---SSPLLAHICGSSLPTSITSTQNTIYVRFRSDSSRDHR----------------GFSARFS--------------------EACGATIVTDDVG-GAIASPRYPAPYPPNQNCSWF---IKAQEPFNHVTLSFTDFEL-EAIDSNCSHDAVEILDGDNYLAPSIGRF-------------CGS-VVPHPVTSFSSAMVV--NFITDVSVSRRGFRAVYS-ASTSSCGGEMVMQ--------------SGAFNSPNYPDAYPPNLECVWTIRSSPGNRVQLSFLTFHLQGDS------------SCENDYLEIRE--GNSTGAL----VGRFCGSSLPSNYTSVSGHI-LWVKFVSDSSDSGAGF---------RATFSHLYGIDVTGES--GQIASPLYPRTYPNNAHYRWTIN-VEGDSYVQIRFLDMDIEDL-YDCYYDHLKIFDGPDVYHYPLGTFCGL--ALPHLIRSSGSTVTLLFKTD-TVVGGRGFLLEWTAVQNSGPSPTIPPGACGG 1974 HSP 4 Score: 111.309 bits (277), Expect = 3.129e-24 Identity = 172/746 (23.06%), Postives = 276/746 (37.00%), Query Frame = 3
Query: 153 NSSIENIFYEHFYSNKMTGGILL-------SPNWPGK-YPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCG-IKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVII----LKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFT-SFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
+ S+ +I ++ YS + GG + SP +PG YP + G + L F +F+++ S C +DY +E++ Y P+L R CG D +P I + ++ + F SD +T Q L F+A+ E+ + +G ISSP YP L P + C +E + R+ L D L C ++VE++N L +D+ R CG + Q SS N + + A S+ N GF ++ SD EP + G D + S GY++S N + C + H+ + VV + +L C+ YL L K CG+ T P+++ L ++F + GFK Y F + G +TG G+++SP Y YPS S C + A I L F F H +C D +T+ G + +YCGT+ PG + S +L + K GFLAS+ S CG I + G I SP++P + + + C W + A +TF+ FQI +S +C + ++++ G P++ L CG+ + P + N I RF + + A+GF
Sbjct: 2308 DGSVTHIGFKAKYSIAICGGTFIGQTGSIHSPGFPGSNYPDMSSCEWYLEGPTGHYLTLRFSNFSLQ-TSSGCSQDY----VEIREYNAT---------GPLLNRHCG---DDLPAPIDTSDSFAFVKFVSDASTSAPGFQ------LFFEASVEACGGEL--------------------NALSGTISSPNYPNLYPHSRVCRWEVVAPPD-RRVTLTINDLRLEASGTSCMFDYVEVLN--GLGADAPRL-QRFCGTVPAGTQVHSSGNSMAIVFRTDA----------------SISNGGFMASYS-SD--EPA---------VCGGILDNPSGGNFTSPGYLVSNYSNNLN-----CEWLIQNPHHINSSIVVLIEDLHLE----NHQTCESDYLQFRLGDSNGDLLAK--------------FCGQT------TPSVPIVVSTSELWVHFQSDSSQGDLGFKAKYMFSECGGW-----------------QTGEEGVLSSPNYPAMYPSPSRCAWLLEAPVGSTITLTFTYFNLEH------------HSTCSWDSVTI-----FNGGSPGSPIIGQYCGTTSPGTIQSGSNTLAIVFLADHSVSKG--GFLASW------STDSSGCGGIIHGDT--GTIKSPNFPQNFPAHVECSWQIIAHE-GNHLEMTFSPDFQIPDSSGTCQESYIKVWSGRTQTPEALLASHCGSVAPGP-IVAPYNMITTRFQS--SGDTAKGF 2901 HSP 5 Score: 109.383 bits (272), Expect = 1.416e-23 Identity = 162/709 (22.85%), Postives = 274/709 (38.65%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIIN-----QPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIY-SVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTD 2312
G+++SPNWP Y + + +Y+ NE+V LNF H ++E S C D Y+EV+ R+ + P++G++CG SL P IVS +N + + F SD + GF+A ++ + S +G+ SP +P P C + + LDF+ F++ + C +FVE+ + P L + CG + S+ +Y++ A S+ N GF+ + +A+ D + G G I SPG + C +F + Q +++L F NL D C YL +Y + + E I RY CG++ +S + +L F +GF SY + + C + S G SP Y ++YP+N C + + N I L F F E P SC+ D++ + R+ G+ + ++CG P LVS L + F S++ + GF A + + + T+ G SP+YP Y + C W++ ++ + L F+ F +E +S+ CS L +++G + ++LCGT+ PS SSS+ + ++ TD
Sbjct: 699 GVIISPNWPNNYAHNRQCIYLIQLPANEKVALNFTHMDLETHS-GCSFD----YVEVR--DGRVEAA------PLIGKYCGTSL---PAPIVSSSNTLWIRFKSDNTVT----------RSGFRAVYTLACGGTL--------------------SGSGQFRSPYHPNNYPHNKLCEWVINQPEGYV-VTLDFLSFDV--EGGSCLFDFVEVRDGSSSSSPLL--------GKFCGTNIPARLQSTQRSMYIQFRTDA----------------SVSNHGFEAVYD--------SAIEGCGDTLTG------------PSGTITSPGHPTSYPHGANCTWFI----SVQPGNLIRLTFNSFNLEYHYD--CNYDYLEVYDNGTVETGKKIGRY-------------CGRSVPPSLTSSERQLTLL---FVSDYSLSLEGFSASYVSIN---------ATTDCGETFTSP----TGFFTSPNYPDYYPNNRDCTFKIIVELNMQILLNFTNFHL-EGFPP----------SCNFDFVEI-----RDGGYETSPLIGKFCGEQKPPALVSHSNRL--WVRFHSDSTTSHSGFTAHWDGTQTGCG--------GTLTTATGGFSSPNYPLPYHPNAECYWNIR-INHGNQVELRFSDFHLE-SSQGCSFDYLAVHDGDSAGAPLLAKLCGTE-LPPSINSSSHQLYIKLRTD 1250 HSP 6 Score: 102.834 bits (255), Expect = 1.287e-21 Identity = 92/323 (28.48%), Postives = 141/323 (43.65%), Query Frame = 3
Query: 1479 TQPVRKEQQGFKLSYRFLKDFGISGTM--VSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQS--ELCGTDSAIPSYFSS-SNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKN 2432
T P++ G L+ RF D +SG S T G I+SP Y N YP+N C + N + L F T D+ ++H +C DY+ + + + L CG+S+P + S Q ++ + F+S++ ++ GF A FS+ CG+ I + G I SP YP Y + C W + A P L+FT F++E +CS+ + I +G N S CG S +P +S S+ + V F+TD+ S RGF+ V++ S SC G + SG S N
Sbjct: 1462 TSPMQVSSTGNLLTVRFKSDAYVSGRGFNASWAEVQGGCGGPITAPSGEIHSPLYPNSYPANVDCSWVISVDHNHRVFLNF----TDLDI--------ELHTNCTWDYVAIHDGPSISSPLL-----AHICGSSLPTSITSTQNTI--YVRFRSDSSRDHRGFSAR---------FSEACGATIVTDDVGGAIASPRYPAPYPPNQNCSWFIKAQEPFNHVTLSFTDFELEAIDSNCSHDAVEILDGDNYLAPSIGRFCG--SVVPHPVTSFSSAMVVNFITDV-SVSRRGFRAVYSA-----STSSCGGEMVMQSGAFNSPN 1748 HSP 7 Score: 90.5077 bits (223), Expect = 7.894e-18 Identity = 162/713 (22.72%), Postives = 270/713 (37.87%), Query Frame = 3
Query: 201 MTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVS-KNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRL---VVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGS--NISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG--FNVKPQSELCGTDSAIPSY-FSSSNFIRVRFLTD 2312
M G SPN+P YP ++ V+ S +V L+F F+++G S SCE DYL+I N + L +GRFCG SL P N S +++ + F SD + GF+A FS Y +T +G+I+SP YP P+ + + E + +++ F+D ++ + C + ++I + P + + CG+ SS + + L V+ GR +++E +++QN G IP C ++ + ++ ++ SP + C + VV+ N L++ +G Y ++ VI LCG+ +++ + + I +F+ + QGF SY S+G + + RG++NSP Y Y +C + F R I + FQ+ + TS + D+L V + L ER CG++ P +L + + F F S+ GF +++ S CG + GYI SP+YP Y ++ C W + + + I F IE T+ SC L I +G N S LCG S PS S+ + + +RF TD
Sbjct: 1739 MQSGAFNSPNYPDAYPPNLECVWTIRSSPGNRVQLSFLTFHLQGDS-SCENDYLEI--------REGNSTGAL-----VGRFCGSSL---PSNYTSVSGHILWVKFVSDSSDS----------GAGFRATFSHLYGIDVT-------------------GESGQIASPLYPRTYPNNAHYRWTINVEGD-SYVQIRFLDMDIEDLYD-CYYDHLKIFDGPDV---YHYPLGTFCGLALPHLIRSSGSTVTLLFKTDTVVGGRGFLLE-------WTAVQNSG-------------------PSPTIPPGACGGQLVAG-ETPAFLFSPAWPGQYPPNQECTWLIR-----SPGSVVEFNVLSLDI---------EGSTPCYFDRMVIRDGATSVSPVIAS------LCGREPPGSFHSTGDSMFI---HFSSDSQVSGQGFNASY-------------SKGCGGFLHVD-----RGVLNSPHYPQNYQPGLNCSW--FVMVTPGFR-ISVTFQSPFQISGSGTSCNS------GDFLEVRNGPDASSPLLG----ERLCGSTPPSLLQTTDNQIYFN--FVSDGSTEASGFKLTFE------AHSKACGGFIELRDLDPPGYITSPNYPQNYPQNIDCIWVIKVPNGEAVQIDFENEFYIESTA-SCLYDYLEIRDGSTLNSDLVSRLCG--STRPSTQHSTGSAMLLRFRTD 2308 HSP 8 Score: 86.2705 bits (212), Expect = 1.564e-16 Identity = 163/701 (23.25%), Postives = 253/701 (36.09%), Query Frame = 3
Query: 225 PNWPG--KYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTD 2312
PN PG +Y V +V N+ + + F +F++E S C D+L I+ + I G++CG + P + S +N + F SD S N + ++A E+ Y G ++SP YPG P +C + L I F NL + C +F+EI D L G +F S+ L+ G + H+ DL S+ + GF I +T S + SEG IISP + C Y N E V LNFT+++L C Y+ + E LI +Y + P ++ N L + S N V + GF+ Y +SG+ G SP++ N YP N C++ ++ L F+ F DV SC D++ V R+ + ++CGT+IP L S Q+S+ + F+++A + GF A Y + CG ++ S G I SP +P Y C W + +V P LTF SF +E C+ L +Y+ V+ ++ CG S PS SS + + F++D
Sbjct: 468 PNTPGHDEYDHQVSCTWVLRTDPNKILRVTFPYFHLE-QSTGCIFDFLQIHDGDSPFSYMI------------GKYCGQT---APAELHSSHNALYFWFRSD-----SSNSGGGF-TVTWQAEDPVCGGELTAPY--------------------GNLNSPGYPGNYPPGRDCYWMVTVNPGLL-ITFAFGTLNL-ESHPNCSYDFLEI------------RDGLLPGDPVLGKFCSTGTPAPLQTT---GPFAWLHFHS-DL---SVSDRGFHITYTTSPSDPGCGGTFT------------------DSEGVIISPNWPNNYAHNRQCIYLIQLPAN----EKVALNFTHMDLETHS--GCSFDYVEVRDGRVEAAPLIGKY---CGTSLPAPIVSSSNTLWIRFKSDNTVT-------------RSGFRAVYTLACGGTLSGS-------------------GQFRSPYHPNNYPHNKLCEWVINQPEGYVVTLDFLSF----DVEGG---------SCLFDFVEV-----RDGSSSSSPLLGKFCGTNIPARLQSTQRSM--YIQFRTDASVSNHGFEAVYDSAI------EGCGDTLTGPS--GTITSPGHPTSYPHGANCTWFI-SVQPGNLIRLTFNSFNLE-YHYDCNYDYLEVYDNGTVETGKKIGRYCGR-SVPPSLTSSERQLTLLFVSD 1015 HSP 9 Score: 81.2629 bits (199), Expect = 4.605e-15 Identity = 161/735 (21.90%), Postives = 275/735 (37.41%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEH-FNIEGLSFSCEK-DYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANG-SYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKL--------SYRFLKDFGISGTMVSRGRCHYRYQSEETG-----YRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKR---KVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHL---HAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG-FNVKPQSELCG-TDSAIPSYFSSSNFIRVRFLTDITSKGARGFQ 2342
G+L SP++P Y + + M + ++ + F+ F I G SC D+L++ +N + S+ L E R CG + P + + +N I +F SD +T+ S GFK F +H +C I G I+SP YP P ++CI+ + + A +++DF + + C +++EI + L+SD +RLCG S+ + + LR S+ +IGFK K++ + IC F+G Q + F N P+M C+ Y YL R+ +T C ++Y++ I + N T P+ G L S+ F+K + T + + E G G I+SP Y N YP + C+++ A + + L T D+ + + SC DY+ V + + LQ R+CGT G V + + F+++A + GF+ASY + + + G N +S GY+ S YS++L CEW + H + ++ +E ++C + L+ G N ++ CG T ++P S+S + V F +D +S+G GF+
Sbjct: 2095 GVLNSPHYPQNYQPGLNCSWFVMVTPGFRISVTFQSPFQISGSGTSCNSGDFLEV-------RNGPDASSPLLGE----RLCGST---PPSLLQTTDNQIYFNFVSDGSTEAS----------GFKLTFE-------------AHSKACGGFIELRDLDPPGYITSPNYPQNYPQNIDCIWVIKVPNGEA-VQIDFENEFYIESTASCLYDYLEIRDGSTLNSD---LVSRLCGSTRPSTQHSTGSAMLLRFRT----------------DGSVTHIGFKAKYSIA------------------------------------------------ICGGTFIG----QTGSIHSPGFPGSNYPDMS--SCE-----WYLEGPTGHYLTLRFSNFSLQTSSG---CSQDYVE----------IREYNATGPLLNRHCGDDLPAPIDTSDSFAFVKFVSDASTSAPGFQLFFEASVEACGGELNALSGTISSPNYPNLYPHSRVCRWEVVAPPDRRVTL------TINDLRLEASG-----TSCMFDYVEVLNGLGADAPRLQ-----RFCGTVPAGTQVHSSGN-SMAIVFRTDASISNGGFMASYSSDEPAVCGGILDNPSGGNFTSP---GYLVS-----NYSNNLNCEWLIQNPHHI--NSSIVVLIEDLHLE-NHQTCESDYLQFRLGDSNGDLLAKFCGQTTPSVPIVVSTSE-LWVHFQSD-SSQGDLGFK 2670 HSP 10 Score: 72.0182 bits (175), Expect = 3.220e-12 Identity = 85/317 (26.81%), Postives = 123/317 (38.80%), Query Frame = 3
Query: 1407 LCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLG--FTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDL-ICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKP-QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQI 2345
LCG T+ N + NF E GFKL++ C + + G I SP Y YP N C + + E +++ F + Y + SC DYL + R+ L ++ R CG++ P S Q S G L F+++ GF A Y F Q GS IHSP +PG D+ CEW+L + L F++F ++ TS CS + I E P + CG D P +S +F V+F++D S A GFQ+
Sbjct: 2164 LCGSTPPSLLQTTDNQIY---FNFVSDGSTEASGFKLTFE-----------AHSKACGGFIELRDLDPPGYITSPNYPQNYPQNIDCIWVIKVPNGEAVQIDF-----------ENEFYIESTASCLYDYLEI-----RDGSTLNSDLVSRLCGSTRP----STQHSTGSAMLLRFRTDGSVTHIGFKAKYSIAICGGTFIGQTGS----------IHSPGFPGSNYPDMSSCEWYLEGPT-GHYLTLRFSNFSLQ-TSSGCSQDYVEIREYNATGPLLNRHCGDDLPAP-IDTSDSFAFVKFVSD-ASTSAPGFQL 2432 HSP 11 Score: 71.2478 bits (173), Expect = 5.865e-12 Identity = 82/304 (26.97%), Postives = 128/304 (42.11%), Query Frame = 3
Query: 1470 LNFTQPVRKEQQGFKLSYRF-LKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILT--FTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSN-FIRVRFLTDITSKGARGFQIVWTRVI 2363
L+F + +GF ++Y D G GT T G+I SP + N Y N C Y +NE + L F T D+ + H C DY+ V R+ +YCGTS+P +VS +L + FKS+ GF R V++ CG +S + G SP++P Y + +CEW ++ E +++T F SF +EG SC + + +G + + CGT+ IP+ S+ + ++F TD S GF+ V+ I
Sbjct: 664 LHFHSDLSVSDRGFHITYTTSPSDPGCGGTF--------------TDSEGVIISPNWPNNYAHNRQCIYLIQLPANEKVALNF----THMDL--------ETHSGCSFDYVEV-----RDGRVEAAPLIGKYCGTSLPAPIVSSSNTL--WIRFKSDNTVTRSGF---------RAVYTLACGGTLSGS---GQFRSPYHPNNYPHNKLCEW---VINQPEGYVVTLDFLSFDVEG--GSCLFDFVEVRDGSSSSSPLLGKFCGTN--IPARLQSTQRSMYIQFRTD-ASVSNHGFEAVYDSAI 914 HSP 12 Score: 70.4774 bits (171), Expect = 1.077e-11 Identity = 66/263 (25.10%), Postives = 113/263 (42.97%), Query Frame = 3
Query: 1575 CHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVK--PQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
C Y+ E G + SP + + YP + C A +N I F F + H SC+ DYL + R + R+CG+++P + Q +L L KS+ GF ++ + CG + +G + SP+YPG Y + CEW++ V+P+ R + +TF I+ C N L++Y+G + P CG ++ I + +SS+ + + F + S GF++ W+
Sbjct: 3376 CSRTYEQE----FGYLKSPGWPDTYPHDVDCTIILKAPTNNSISFFFNAFDV------------ESHDSCNFDYLEI-----RNGSTASSPLIGRFCGSTLPSPIFPQSNTL--YLHCKSDFSSTRDGFDVTW------TSSPNGCGGILYGD--HGSLSSPNYPGTYPNQSHCEWNI--VAPRGRVVTVTFGQISIDDPGD-CQNNFLKLYDGPDSSSLPVGPYCGVETNIAPFRASSHQVFIVFQSQF-SILPSGFRLTWS 3603 HSP 13 Score: 63.929 bits (154), Expect = 9.389e-10 Identity = 70/246 (28.46%), Postives = 103/246 (41.87%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEM--CPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFF--SSH 935
G L SP WP YP DV + N + F F++E SC DYL+I +N S+ P++GRFCG +L P I ++N + L SD FS +D GF W SS + C +++ + G +SSP YPG P+ +C + + R R+ + F D+ C F+++ + P DS S CG++ N F SSH
Sbjct: 3385 GYLKSPGWPDTYPHDVDCTIILKAPTNNSISFFFNAFDVESHD-SCNFDYLEI-------RNGSTASS-----PLIGRFCGSTL---PSPIFPQSNTLYLHCKSD----FSSTRD------GFDVT------------WTSSPN-GCGGILYGD---HGSLSSPNYPGTYPNQSHCEWNIVAP----RGRVVTVTFGQISIDDPGDCQNNFLKLYDGP--DSSSLPV-GPYCGVETNIAPFRASSH 3581 HSP 14 Score: 63.929 bits (154), Expect = 1.030e-9 Identity = 146/730 (20.00%), Postives = 251/730 (34.38%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANG---SYTGEISSPTYPGL-LPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD----NRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVV---QLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSI-PGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPS-YFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G ++SPN+P YP + Y E + L F+ F +E S +C D L IY N+ + CG S+ +S +++ F+SD + GF A ++ I G S TG +SSP + NC + R + + L F F+L + C + V + D D+ R CG SS N L++ + SS+ IG++ T+++ P GY+ P S P + + ++ +E+ +N T+ + C+ Y+ +Y M + + CG + + ++ N L + F ++QGF +YR + F GT+ T + SP + N YP ++SC++ A E I++ F D SC +YL + + + G ++ +C + + P S +++ + FKS+ G G ++Q + + + +GY+ SP +P Y D+ C L A + F +F +E + SC+ L I G CG S +PS F SN + + +D +S GF + WT
Sbjct: 2918 GRVVSPNYPADYPDNSNCNYTIDAGEQTVIILTFQVFQLEAHS-TCFYDGLKIY-------------NLPVSSTAVATLCGSSVP----GPISTFGPMLVHFYSDSIST----------DTGFMAEYT---------------------AIPCGGFFNSTTGTVSSPALSIINYHHNTNCTFHIRVRADRV-VNLRFNTFHL-EASSSCRYDSVSV-------HDGQDSLAPLLGRFCGTALPPDLRSSSNELFIVFIT----------------DSSVNGIGWRA--TYAETLGPEQGC----------------------GGYLSMPMGMLGSPDPNLDGRYEPSMNCVWTIEMPVNRAINLTFSSFELESSATCRYDYVKVYD-GHNMDFPLV------------GTFCGTSIPAFFMSTGN---FLTIQFVTDSSVQRQGFNATYRAVPLF-CGGTL------------NATTTIQTLTSPSFPNTYPPHTSCRWTLDAPGQETIKVSVQTFVLQPD------------QSCSTNYLQIHDWPLGDFG-----QSHTFCASDMHPPDFYSYGRTV--LVDFKSDHFMTGNGLSFTFQIANCSRTYEQE----------FGYLKSPGWPDTYPHDVDCTIILKAPT-NNSISFFFNAFDVE-SHDSCNFDYLEIRNGSTASSPLIGRFCG--STLPSPIFPQSNTLYLHCKSDFSST-RDGFDVTWT 3486 HSP 15 Score: 56.9954 bits (136), Expect = 1.256e-7 Identity = 69/267 (25.84%), Postives = 111/267 (41.57%), Query Frame = 3
Query: 1662 SCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF--NVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFN 2456
SC + N+++R+ F F + C D+L +I ++ F + +YCG + P L S +L F F+S++ +G GF ++Q + V CG + T+ YG ++SP YPG Y C W + V+P F + +E + +CS L I +G + C T + P ++ F + F +D+ S RGF I +T S+ C G + G IS N N N
Sbjct: 481 SCTWVLRTDPNKILRVTFPYFHLEQST------------GCIFDFL---QIHDGDSPF--SYMIGKYCGQTAPAELHSSHNALYFW--FRSDSSNSGGGFTVTWQ--AEDPV----CGGEL--TAPYGNLNSPGYPGNYPPGRDCYWMV-TVNPGLLITFAFGTLNLE-SHPNCSYDFLEIRDGLLPGDPVLGKFCSTGTPAP-LQTTGPFAWLHFHSDL-SVSDRGFHITYTT---SPSDPGCGGTFTDSEGVIISPNWPNNYAHN 713 HSP 16 Score: 56.9954 bits (136), Expect = 1.332e-7 Identity = 68/256 (26.56%), Postives = 110/256 (42.97%), Query Frame = 3
Query: 1572 RCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYP-GRYSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFN-VKP-QSELCGTDSAIPSYFSSSNFIRVRFLTDITSKG 2327
RC + + G + SP Y YP NS+C Y A +I L F VFQ + H +C D L + + + + CG+S+PG + + L + F S++ GF+A Y I CG +ST+ G + SP Y + C +H+ + +R + L F +F +E +S SC + +++G + + P CGT + P SSSN + + F+TD + G
Sbjct: 2908 RCGANFSAPS----GRVVSPNYPADYPDNSNCNYTIDAGEQTVIILTFQVFQL------------EAHSTCFYDGLKIYNLP------VSSTAVATLCGSSVPGPISTFGPML---VHFYSDSISTDTGFMAEYTAIP--------CGGFFNSTT--GTVSSPALSIINYHHNTNCTFHIRVRA--DRVVNLRFNTFHLEASS-SCRYDSVSVHDGQDSLAPLLGRFCGT-ALPPDLRSSSNELFIVFITDSSVNG 3124 HSP 17 Score: 51.2174 bits (121), Expect = 6.406e-6 Identity = 56/260 (21.54%), Postives = 104/260 (40.00%), Query Frame = 3
Query: 114 DLFLMFLSITKIANSSIENIFYEHFYSNKMTGGIL---------LSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLD 866
+LF++F++ + + + E + GG L PN G+Y + V+ N ++L F F +E S +C DY+ +Y + N+ F P++G FCG S IP +S N + + F +D + Q + GF A + + + C ++A + ++SP++P P +C + + I++ F L Q D+ C +++I + P D
Sbjct: 3111 ELFIVFITDSSVNGIGWRATYAETLGPEQGCGGYLSMPMGMLGSPDPNLDGRYEPSMNCVWTIEMPVNRAINLTFSSFELES-SATCRYDYVKVY----------DGHNMDF--PLVGTFCGTS---IPAFFMSTGNFLTIQFVTDSSVQ----------RQGFNATY-----RAVPLF--------CGGTLNATTTIQ-TLTSPSFPNTYPPHTSCRWTLDAPGQ-ETIKVSVQTFVL-QPDQSCSTNYLQIHDWPLGD 3328
BLAST of Cubilin vs. Ensembl Medaka
Match: bmp1a (bone morphogenetic protein 1 [Source:NCBI gene;Acc:100125511]) HSP 1 Score: 80.1073 bits (196), Expect = 8.584e-15 Identity = 142/649 (21.88%), Postives = 232/649 (35.75%), Query Frame = 3
Query: 198 KMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITK------------------------YWASSHHSSC-----FYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLN------------------------ALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIK 1985
K G + SPN+P Y + ++ SE V L F+ F IE SC DYL++ R IS + P+LGRFCG+ P +I + +N + + F SD + + K GF ANF FK + +K Y ++ SC ++ NGS I+SP +P P NCI++ + T RI L F F + +++C +FVE+ + DS + + CG + S +N + + +++ GFK +F FSDK E L+ + CD + S G I SP + K C + +T +++ F +++ D C ++ IY + R+ KP ++ N L + S N V +++GF S+ C ++E ++ F N YP S C++ A+ + LIF F+ E+ C DY+ + + ++ + RYCG+ P + S S+ + F S+ N GF Y K
Sbjct: 424 KRDNGQIQSPNYPDDYRPNKACIWKISVSEGYHVGLTFQSFEIERHD-SCAYDYLEV---------RDGISE---NSPLLGRFCGYDK---PDDIKTSSNHLWMKFVSDGS----------VNKAGFAANF-FKEMDECSKPDNGRCEQRCVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNGS----ITSPGWPREYPPNKNCIWQLVA-PTQYRITLLFDVFET-EGNDVCKYDFVEVRSGLSADSKPH---GKFCGSEKPEAITSQYNNMRIEFKS----------------DNTVSKKGFKAQF-FSDKDECSKENGGCQHDCVNTFGSYRCQCRSGFVLHENKHDCKEAGCDHTVNS---VSGAITSPNWPDKYPSKKACTWAL----STTPGHRIKIAFNEIDMEAHLD--CAYDHIQIYDGRDAKAPSLGRF---CGSKKPQPIISSGNKLFIRFFSDNSV-------------QKKGFDASH--------------SAECGGILKAEVKTKDLFSHAQFGDNNYPGASDCEWVISAEKGYGVELIFQTFEIEEEA------------DCGYDYMELFDGAD-----TKSPRLGRYCGSGPPEEIYSAGDSI--VIKFHSDDTINKKGFHVRYTSTK 961 HSP 2 Score: 63.1586 bits (152), Expect = 1.478e-9 Identity = 74/271 (27.31%), Postives = 120/271 (44.28%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGF--NVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLS---NGSCPGFQCLNS 2411
G +SP + N Y + C + E I L F TS D+ + HL C D++ + R+ + + R+CG +P ++S L + F+S+++ G GF A Y+ I CG ++ + G I SP+YP Y + C W + +VS LTF SF+IE SC+ L + +G N CG D +SSN + ++F++D + A GF + + + S NG C +C+N+
Sbjct: 315 GNFSSPGFPNGYSAYMHCIWRISVTPGEKIILNF----TSMDL-------YRSHL-CWYDHVEI-----RDGYWRKAPLKGRFCGDKLPEPIISTDSRL--WIEFRSSSNWVGKGFSAVYEAI---------CGGDVKRDN--GQIQSPNYPDDYRPNKACIWKI-SVSEGYHVGLTFQSFEIE-RHDSCAYDYLEVRDGISENSPLLGRFCGYDKP-DDIKTSSNHLWMKFVSDGSVNKA-GFAANFFKEMDECSKPDNGRCEQ-RCVNT 550
BLAST of Cubilin vs. Ensembl Medaka
Match: pcolce2b (procollagen C-endopeptidase enhancer 2 [Source:NCBI gene;Acc:101171953]) HSP 1 Score: 77.411 bits (189), Expect = 2.127e-14 Identity = 69/251 (27.49%), Postives = 108/251 (43.03%), Query Frame = 3
Query: 1602 TGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGR-YSSDLICEWHLHAVSPKERFI-LTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSEL---CGTDSAIPSYFSSSNFIRVRFLTDITSKGARGF 2339
TG G+I S Y YP N+ C + +++ L F D +L C DY+ V +G + + R+CGT PG LVS + L S+A+ G GFLA + + CG + + G +P++P + Y + + C WH+ V+PK + I + F F +E C + I+ G + + CG DS FS N + ++FL+D+ S A GF
Sbjct: 36 TGESGVIGSQGYPGVYPPNTKCVWRITVPEGKVVVLSFRTIDLEND-----------NL-CRYDYVDV------YSGHISAQRLGRFCGTFKPGSLVSTGNKM--LLQMVSDANTAGSGFLAVFSAAHPHERGDQYCGGRLVKPN--GTFKTPNWPEKDYPAGVTCSWHI--VAPKNQIIEVKFEKFDVE-RDNYCRYDHVSIFNGAEINDARRIGKYCG-DSPPAPVFSEGNQVLIQFLSDL-SLTADGF 259 HSP 2 Score: 62.7734 bits (151), Expect = 8.045e-10 Identity = 70/287 (24.39%), Postives = 119/287 (41.46%), Query Frame = 3
Query: 111 WDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKY-NEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGL-LPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDAD--NRLCGIKDNFQFFSSHNRLYLRLV 959
W L L+ T++ S + + G++ S +PG YP + + V+ E + V L+F ++E + C DY+D+Y S + LGRFCG F P ++VS N ++L SD NT S GF A FS + +E +Y L+ NG++ +P +P P+ + C + + I + F F++ ++D C + V I N ++ NDA + CG FS N++ ++ +
Sbjct: 11 WSLLLL----TQVCAQSERRPIFTCGGNITGESGVIGSQGYPGVYPPNTKCVWRITVPEGKVVVLSFRTIDLENDNL-CRYDYVDVYSGHISAQR-------------LGRFCG---TFKPGSLVSTGNKMLLQMVSDANTAGS----------GFLAVFSAAHPHERGDQYCGGR-------LVKPNGTF----KTPNWPEKDYPAGVTCSWHIVAPKNQI-IEVKFEKFDV-ERDNYCRYDHVSIFNGAEI----NDARRIGKYCGDSPPAPVFSEGNQVLIQFL 249
BLAST of Cubilin vs. Ensembl Medaka
Match: tll1 (tolloid like 1 [Source:NCBI gene;Acc:101160961]) HSP 1 Score: 78.1814 bits (191), Expect = 3.110e-14 Identity = 68/280 (24.29%), Postives = 117/280 (41.79%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNE--------------MITKYWASSHH-------------SSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLA 968
G + +P WP +YP + V+ + ++ + FE F +EG C+ DY+++ S + + G++CG +P I S+ N + ++F SD + K GFKA+F +E + Y H + C + IH S +G +SSP +P PS C ++ + + R+++ F +F + Q E C + +E + DSD+ RLCG K S+ N++YLR + A
Sbjct: 538 GTISTPGWPKEYPPNKNCVWQVVAPTQYRISMQFEAFELEGNEV-CKYDYVEVR------------SGLSSDSKLHGKYCGTE---VPEVITSQYNNVRIEFKSDNT----------VSKKGFKAHFFSDKDECSKDNGGCQHECINTVGSYVCQCRHGFVLHENKHDCKEAECEHKIH---SPSGTLSSPNWPDKYPSRKECTWDI-TATPGHRVKISFNEFEIEQHQE-CAYDHLEAFDG---DSDTAAILGRLCGGKIPEPLVSTSNKMYLRFISDA 783 HSP 2 Score: 73.559 bits (179), Expect = 9.099e-13 Identity = 78/273 (28.57%), Postives = 117/273 (42.86%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLS--CHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG-FNVKPQ-SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTR---VIPRLSNGSCPGFQCLNS 2411
G +SP Y N YPS + C + E I L F D++ S C DY+ V + R+ L R+CG IP +LVS + + F+S+++ G GF A Y+ I CG I+ S G I SP+YP Y C W + VS L+F +F++E SC+ L + +G P CG D S+SN + ++F++D T A GF + + + NG C +C+N+
Sbjct: 269 GNFSSPGYPNGYPSYTHCVWRISVTPGEKIVLNFTTM--------------DLYKSSLCWYDYIEVRDGYWRKAPLLG-----RFCGDKIPEVLVSTDSRM--WIEFRSSSNWVGKGFAAVYEAI---------CGGEITKDS--GQIQSPNYPDDYRPSKECVWRI-TVSEGYNVGLSFQAFEVE-RHDSCAYDYLEVRDGPLETSPLIGRFCGYDKP-EDVRSTSNTLWMKFVSDGTVNKA-GFAANFFKEEDECAKPDNGGCEQ-RCVNT 504 HSP 3 Score: 60.4622 bits (145), Expect = 9.361e-9 Identity = 72/291 (24.74%), Postives = 120/291 (41.24%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNA 1082
G L SPNWP KYP + + +V ++F F IE C D+L+ ++ + + I LGR CG IP +VS +N + L F SD + Q + GF+A S E + A +H + + HA + YPG +C + SE + I L FI F + +++ C +F+E+ N D++++ R CG +S + + +R H+ D ++ GF +++T + E L+A
Sbjct: 694 GTLSSPNWPDKYPSRKECTWDITATPGHRVKISFNEFEIEQHQ-ECAYDHLE------AFDGDSDTAAI------LGRLCGGK---IPEPLVSTSNKMYLRFISDASVQ----------RKGFQAAHS---TECGGRLKAEAHQKNLYS--HA------QFGDNNYPG----HTDCEWLLTSEEGYS-IELTFITFEV-EEEADCGYDFIELFN--GYDANAHRL-GRFCGSGPREGIYSPGDVMLIRF------------HSDD----TISKKGFHLRYTSTKFQENLHA 922 HSP 4 Score: 58.151 bits (139), Expect = 4.255e-8 Identity = 58/251 (23.11%), Postives = 98/251 (39.04%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYG--YIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G ++SP + + YPS C +D A +++ F F+ + H C D+L + L R CG IP LVS + L F S+A GF A++ S +CG + + ++ Y H+ Y CEW L + LTF +F++E C + ++ G++ CG+ +S + + +RF +D T +GF + +T
Sbjct: 694 GTLSSPNWPDKYPSRKECTWDITATPGHRVKISFNEFEIEQ------------HQECAYDHLEAFDGDSDTAAILG-----RLCGGKIPEPLVSTSNKM--YLRFISDASVQRKGFQAAH---------STECGGRLKAEAHQKNLYSHAQFGDNNYPGHTDCEWLLTS-EEGYSIELTFITFEVE-EEADCGYDFIELFNGYDANAHRLGRFCGS-GPREGIYSPGDVMLIRFHSDDTIS-KKGFHLRYT 912 HSP 5 Score: 56.9954 bits (136), Expect = 1.132e-7 Identity = 64/250 (25.60%), Postives = 102/250 (40.80%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLV 959
G SP +P YP V+ + E++ LNF ++ S C D YIEV+ R P+LGRFCG D IP +VS ++ + ++F S N +GK GF A + ITK +G+I SP YP + C++ + S + L F F + + D C +++E+ + P +++ R CG S+ N L+++ V
Sbjct: 269 GNFSSPGYPNGYPSYTHCVWRISVTPGEKIVLNFTTMDLYKSSL-CWYD----YIEVRDGYWR--------KAPLLGRFCG---DKIPEVLVSTDSRMWIEFRSSSNW---------VGK-GFAAVYEAICGGEITK-------------------DSGQIQSPNYPDDYRPSKECVWRI-TVSEGYNVGLSFQAFEVERHDS-CAYDYLEVRDGPL---ETSPLIGRFCGYDKPEDVRSTSNTLWMKFV 468
BLAST of Cubilin vs. Ensembl Medaka
Match: tll1 (tolloid like 1 [Source:NCBI gene;Acc:101160961]) HSP 1 Score: 77.7962 bits (190), Expect = 4.601e-14 Identity = 70/280 (25.00%), Postives = 119/280 (42.50%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNE--------------MITKYWASSHH-------------SSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLA 968
G + +P WP +YP + V+ + ++ + FE F +EG C+ DY+++ S + + G++CG +P I S+ N + ++F SD NT + K GFKA+F +E + Y H + C + IH S +G +SSP +P PS C ++ + + R+++ F +F + Q E C + +E + DSD+ RLCG K S+ N++YLR + A
Sbjct: 637 GTISTPGWPKEYPPNKNCVWQVVAPTQYRISMQFEAFELEGNEV-CKYDYVEVR------------SGLSSDSKLHGKYCGTE---VPEVITSQYNNVRIEFKSD-NT---------VSKKGFKAHFFSDKDECSKDNGGCQHECINTVGSYVCQCRHGFVLHENKHDCKEAECEHKIH---SPSGTLSSPNWPDKYPSRKECTWDI-TATPGHRVKISFNEFEIEQHQE-CAYDHLEAFDG---DSDTAAILGRLCGGKIPEPLVSTSNKMYLRFISDA 882 HSP 2 Score: 73.9442 bits (180), Expect = 7.381e-13 Identity = 78/273 (28.57%), Postives = 117/273 (42.86%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLS--CHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEG-FNVKPQ-SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTR---VIPRLSNGSCPGFQCLNS 2411
G +SP Y N YPS + C + E I L F D++ S C DY+ V + R+ L R+CG IP +LVS + + F+S+++ G GF A Y+ I CG I+ S G I SP+YP Y C W + VS L+F +F++E SC+ L + +G P CG D S+SN + ++F++D T A GF + + + NG C +C+N+
Sbjct: 368 GNFSSPGYPNGYPSYTHCVWRISVTPGEKIVLNFTTM--------------DLYKSSLCWYDYIEVRDGYWRKAPLLG-----RFCGDKIPEVLVSTDSRM--WIEFRSSSNWVGKGFAAVYEAI---------CGGEITKDS--GQIQSPNYPDDYRPSKECVWRI-TVSEGYNVGLSFQAFEVE-RHDSCAYDYLEVRDGPLETSPLIGRFCGYDKP-EDVRSTSNTLWMKFVSDGTVNKA-GFAANFFKEEDECAKPDNGGCEQ-RCVNT 603 HSP 3 Score: 60.077 bits (144), Expect = 1.090e-8 Identity = 72/291 (24.74%), Postives = 120/291 (41.24%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNA 1082
G L SPNWP KYP + + +V ++F F IE C D+L+ ++ + + I LGR CG IP +VS +N + L F SD + Q + GF+A S E + A +H + + HA + YPG +C + SE + I L FI F + +++ C +F+E+ N D++++ R CG +S + + +R H+ D ++ GF +++T + E L+A
Sbjct: 793 GTLSSPNWPDKYPSRKECTWDITATPGHRVKISFNEFEIEQHQ-ECAYDHLE------AFDGDSDTAAI------LGRLCGGK---IPEPLVSTSNKMYLRFISDASVQ----------RKGFQAAHS---TECGGRLKAEAHQKNLYS--HA------QFGDNNYPG----HTDCEWLLTSEEGYS-IELTFITFEV-EEEADCGYDFIELFN--GYDANAHRL-GRFCGSGPREGIYSPGDVMLIRF------------HSDD----TISKKGFHLRYTSTKFQENLHA 1021 HSP 4 Score: 58.5362 bits (140), Expect = 3.644e-8 Identity = 58/251 (23.11%), Postives = 98/251 (39.04%), Query Frame = 3
Query: 1614 GLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYG--YIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQ--SELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWT 2354
G ++SP + + YPS C +D A +++ F F+ + H C D+L + L R CG IP LVS + L F S+A GF A++ S +CG + + ++ Y H+ Y CEW L + LTF +F++E C + ++ G++ CG+ +S + + +RF +D T +GF + +T
Sbjct: 793 GTLSSPNWPDKYPSRKECTWDITATPGHRVKISFNEFEIEQ------------HQECAYDHLEAFDGDSDTAAILG-----RLCGGKIPEPLVSTSNKM--YLRFISDASVQRKGFQAAH---------STECGGRLKAEAHQKNLYSHAQFGDNNYPGHTDCEWLLTS-EEGYSIELTFITFEVE-EEADCGYDFIELFNGYDANAHRLGRFCGS-GPREGIYSPGDVMLIRFHSDDTIS-KKGFHLRYT 1011 HSP 5 Score: 56.6102 bits (135), Expect = 1.314e-7 Identity = 64/250 (25.60%), Postives = 102/250 (40.80%), Query Frame = 3
Query: 210 GILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLV 959
G SP +P YP V+ + E++ LNF ++ S C D YIEV+ R P+LGRFCG D IP +VS ++ + ++F S N +GK GF A + ITK +G+I SP YP + C++ + S + L F F + + D C +++E+ + P +++ R CG S+ N L+++ V
Sbjct: 368 GNFSSPGYPNGYPSYTHCVWRISVTPGEKIVLNFTTMDLYKSSL-CWYD----YIEVRDGYWR--------KAPLLGRFCG---DKIPEVLVSTDSRMWIEFRSSSNW---------VGK-GFAAVYEAICGGEITK-------------------DSGQIQSPNYPDDYRPSKECVWRI-TVSEGYNVGLSFQAFEVERHDS-CAYDYLEVRDGPL---ETSPLIGRFCGYDKPEDVRSTSNTLWMKFV 567
BLAST of Cubilin vs. Planmine SMEST
Match: SMESG000080965.1 (SMESG000080965.1) HSP 1 Score: 1924.83 bits (4985), Expect = 0.000e+0 Identity = 951/953 (99.79%), Postives = 952/953 (99.90%), Query Frame = 3
Query: 90 MLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGXXXXXXXXXXXXXXXXXXXQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 2948
MLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNR YLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQS+ETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV
Sbjct: 1 MLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRFYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSDETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 953
BLAST of Cubilin vs. Planmine SMEST
Match: SMESG000080965.1 (SMESG000080965.1) HSP 1 Score: 1912.12 bits (4952), Expect = 0.000e+0 Identity = 947/953 (99.37%), Postives = 948/953 (99.48%), Query Frame = 3
Query: 90 MLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGXXXXXXXXXXXXXXXXXXXQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 2948
MLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNR YLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQS+ETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEG CSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV
Sbjct: 1 MLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRFYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSDETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEG----CSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 949
BLAST of Cubilin vs. Planmine SMEST
Match: SMESG000080965.1 (SMESG000080965.1) HSP 1 Score: 1862.81 bits (4824), Expect = 0.000e+0 Identity = 929/953 (97.48%), Postives = 932/953 (97.80%), Query Frame = 3
Query: 90 MLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGXXXXXXXXXXXXXXXXXXXQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 2948
MLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNR YLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQS+ETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIR+ R + I RLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV
Sbjct: 1 MLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMGSENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDFFSDKNTQFSYNQDDHMGKLGFKANFSFKYNEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRFYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSDETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRI---------SDRYY-------IKRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 937
BLAST of Cubilin vs. Planmine SMEST
Match: SMESG000080965.1 (SMESG000080965.1) HSP 1 Score: 1571.6 bits (4068), Expect = 0.000e+0 Identity = 778/782 (99.49%), Postives = 781/782 (99.87%), Query Frame = 3
Query: 603 NEMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGXXXXXXXXXXXXXXXXXXXQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 2948
++MITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNR YLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQS+ETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV
Sbjct: 104 DKMITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRFYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSDETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 885
BLAST of Cubilin vs. Planmine SMEST
Match: SMESG000080965.1 (SMESG000080965.1) HSP 1 Score: 1565.82 bits (4053), Expect = 0.000e+0 Identity = 778/780 (99.74%), Postives = 779/780 (99.87%), Query Frame = 3
Query: 609 MITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGXXXXXXXXXXXXXXXXXXXQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 2948
MITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNR YLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQS+ETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV
Sbjct: 1 MITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADNRLCGIKDNFQFFSSHNRFYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSDETGYRGLINSPFYTNFYPSNSSCQYDFFAKSNEMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTERYCGTSIPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKKRKVFSDQCGSNISSTSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQIEGTSKSCSNAVLRIYEGFNVKPQSELCGTDSAIPSYFSSSNFIRVRFLTDITSKGARGFQIVWTRVIPRLSNGSCPGFQCLNSGHCISKNLTCNKVFNCGSYVNNSGLPTIDRSDEVQACPVAENYTYLYSGLVIVAVILVIFIVIIIYFIQKNKYLLKRKLRSIEHLDDFVEQNYSSPNISLKKEISIQTPSGSLKIIPKRHFHDSSDNFLFKNHDLINRCRQFSLDLVDTSSKMKRTDNFDSMSEYGLLFREKMQKISIV 780 HSP 2 Score: 50.0618 bits (118), Expect = 9.210e-6 Identity = 125/560 (22.32%), Postives = 207/560 (36.96%), Query Frame = 3
Query: 138 ITKIANSSIENIFYEHFYSNKMTGGILLSPNWPGKYPQDVRYVYVFMG-SENEQVHLNFEHFNIEGLSFSCEKDYLDIYIEVKSYKNRINISNILFHEPVLGRFCGHSLDFIPHNIVSKNNVIILDF--FSDKNTQFSYNQDD----HMGKLGFKANFSF--KYNEMITKYWASSH--HSSCFYLIHANGSYTGEISSP--TYPGLLPSTLNCIY-EFRSESTLARIRLDFIDFNLYQ-QDEMCPVEFVEI----------INQPQLDSDSNDADNRLCGIKDNFQFFSSHNRLYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQS-EGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKC---QDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCGKNYLKYSYTSRNPVIILKLNFTQPVRKEQQGFKLSYRFLKDFGISGTMVSRGRCHYRYQSEETGYRGLINSPFYTNFYPSNSSCQYDFFAKS-NEMIRLIFIVFQ 1727
ITK SS + + ++N G + SP +PG P + +Y F S ++ L+F FN+ C ++++I + + + + N R CG +F S +N L + +N + D + +GFK F+F KY + Y H + C I ++ G I SP L P N + + + ++L+F NL + +D C ++ I I + + D LCG N+ +S +R V++ N+ + GFK+ + F + + +R C + QS + G I SP + C Y F N E+++L F E K D +LS + + ++KR ++ K ++ CG + + S+ + L F K GF SY+F+K V +C S T Y G I+SP Y Y S+ C++ A S E L F FQ
Sbjct: 2 ITKYWASSHHSSCFYLIHANGSYTGEISSPTYPGLLPSTLNCIYEFRSESTLARIRLDFIDFNLYQQDEMCPVEFVEIINQPQLDSDSNDADN---------RLCGIKDNF---QFFSSHNRFYLRLVVLAGRNYMMEPHNIDLYKSSLQNIGFKIKFTFSDKYEPLNALYNRQDHIPGTECDIKIQSSDQSEGYIISPGINRASLAPKICNYFFMGIHNTQNMEVVQLNFTYLNLPEMKDFKCQDGYLSIYSVSFEMKYLIKRYRTVIKETKPDQVLCG--KNYLKYSYTSR---NPVIILKLNFTQPVRK--------EQQGFKLSYRFLKDFGISGTMVSR------GRCHYRYQSDETGYRGLINSPFYTNFYPSNSSCQYDFFAKSN----EMIRLIFIVFQTSEDVPAKLTSYHDVHLSCHQDYLTVAEIVKRENGFLQTNKTER-YCGTS-IPGILVSQQKSLGFTLTFKSNAHKNGPGFLASYQFIKK-----RKVFSDQCGSNISS--TSYYGYIHSPHYPGRYSSDLICEWHLHAVSPKERFILTFTSFQ 517 The following BLAST results are available for this feature:
BLAST of Cubilin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cubilin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cubilin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Cubilin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cubilin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cubilin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cubilin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cubilin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cubilin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cubilin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Cubilin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Cubilin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Cubilin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Cubilin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30006027 ID=SMED30006027|Name=Cubilin|organism=Schmidtea mediterranea sexual|type=transcript|length=2960bpback to top protein sequence of SMED30006027-orf-1 >SMED30006027-orf-1 ID=SMED30006027-orf-1|Name=SMED30006027-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=956bp MIMLILAMRWDLFLMFLSITKIANSSIENIFYEHFYSNKMTGGILLSPNWback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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