T box transcription factor tbx2

Overview
NameT box transcription factor tbx2
Smed IDSMED30006011
Length (bp)1113
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of T box transcription factor tbx2 (SMED30006011) t-SNE clustered cells

Violin plots show distribution of expression levels for T box transcription factor tbx2 (SMED30006011) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of T box transcription factor tbx2 (SMED30006011) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for T box transcription factor tbx2 (SMED30006011) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30006011

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Category 2 cellSMED30006011h1SMcG0003437 SMED30006011smed_20140614PMID:29100657
Cheng et al., 2018
whole organism asexual adult fluorescence in situ hybridization evidence
neoblastSMED30006011h1SMcG0003437 SMED30006011smed_20140614PMID:29100657
Cheng et al., 2018
whole organism asexual adult fluorescence in situ hybridization evidence
X1 cellSMED30006011h1SMcG0003437 SMED30006011smed_20140614PMID:29100657
Cheng et al., 2018
FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30006011h1SMcG0003437 dd_Smed_v4_17143_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30006011h1SMcG0003437 dd_Smed_v4_17143_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30006011h1SMcG0003437 dd_Smed_v4_17143_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30006011h1SMcG0003437 dd_Smed_v4_17143_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of T box transcription factor tbx2 vs. Ensembl Human
Match: TBX2 (T-box transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11597])

HSP 1 Score: 232.261 bits (591), Expect = 2.047e-69
Identity = 107/196 (54.59%), Postives = 147/196 (75.00%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F    TEMVITK+GRRMFP FKVR+ GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  103 DDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 295          
BLAST of T box transcription factor tbx2 vs. Ensembl Human
Match: TBX3 (T-box transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11602])

HSP 1 Score: 228.794 bits (582), Expect = 5.637e-68
Identity = 105/192 (54.69%), Postives = 146/192 (76.04%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            V LE KELW +F  + TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DI+ +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 293          
BLAST of T box transcription factor tbx2 vs. Ensembl Human
Match: TBX3 (T-box transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11602])

HSP 1 Score: 216.468 bits (550), Expect = 2.714e-63
Identity = 105/212 (49.53%), Postives = 146/212 (68.87%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDV--------------------IILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            V LE KELW +F  + TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DI+ +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK                        ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 313          
BLAST of T box transcription factor tbx2 vs. Ensembl Human
Match: TBX6 (T-box transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:11605])

HSP 1 Score: 207.608 bits (527), Expect = 1.698e-62
Identity = 100/201 (49.75%), Postives = 138/201 (68.66%), Query Frame = 1
Query:  214 VRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENC-SLKKER 807
            + SL    + LE++ELW EF +  TEM+ITK GRRMFP+ +V + GLDP A+Y+ LLD++  +  RY++   +W  SGKAE  +   +   +IHPDSP TG  WM + +SFH++KL+N+ +D    +IL+SMHKY P+++LVRA  L   ++     F F ET FI+VTAYQN QIT+LKI  NPFAKGFREN  + K+ER
Sbjct:   85 LHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRV---YIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRER 282          
BLAST of T box transcription factor tbx2 vs. Ensembl Human
Match: TBX6 (T-box transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:11605])

HSP 1 Score: 207.608 bits (527), Expect = 1.698e-62
Identity = 100/201 (49.75%), Postives = 138/201 (68.66%), Query Frame = 1
Query:  214 VRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENC-SLKKER 807
            + SL    + LE++ELW EF +  TEM+ITK GRRMFP+ +V + GLDP A+Y+ LLD++  +  RY++   +W  SGKAE  +   +   +IHPDSP TG  WM + +SFH++KL+N+ +D    +IL+SMHKY P+++LVRA  L   ++     F F ET FI+VTAYQN QIT+LKI  NPFAKGFREN  + K+ER
Sbjct:   85 LHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRV---YIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRER 282          
BLAST of T box transcription factor tbx2 vs. Ensembl Celegans
Match: tbx-2 (T-box protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q19691])

HSP 1 Score: 211.075 bits (536), Expect = 2.165e-64
Identity = 102/199 (51.26%), Postives = 149/199 (74.87%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRA---QNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P VEL+++ELW +F    TEMVITK+GRR+FP+++V+I GLD  ++Y +++D+V ++E+RYK+ +++W+ +GKA  E+ + L   +IHPDSP+TGE WMSK  +FHK+KL+N   DK    ILNSMHKY P+L++VR     NL+Y+ +     F F ET+FIAVTAYQN+++T+LKI  NPFAKGFR+  + K+E+
Sbjct:   59 DDPKVELDERELWQQFSQCGTEMVITKSGRRIFPAYRVKISGLDKKSQYFVMMDLVPADEHRYKFNNSRWMIAGKADPEMPKTL---YIHPDSPSTGEHWMSKGANFHKLKLTNNISDKHGYTILNSMHKYQPRLHVVRCADRHNLMYSTF---RTFVFRETEFIAVTAYQNEKVTELKIENNPFAKGFRDAGAGKREK 251          
BLAST of T box transcription factor tbx2 vs. Ensembl Celegans
Match: tbx-2 (T-box protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q19691])

HSP 1 Score: 211.075 bits (536), Expect = 2.165e-64
Identity = 102/199 (51.26%), Postives = 149/199 (74.87%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRA---QNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P VEL+++ELW +F    TEMVITK+GRR+FP+++V+I GLD  ++Y +++D+V ++E+RYK+ +++W+ +GKA  E+ + L   +IHPDSP+TGE WMSK  +FHK+KL+N   DK    ILNSMHKY P+L++VR     NL+Y+ +     F F ET+FIAVTAYQN+++T+LKI  NPFAKGFR+  + K+E+
Sbjct:   59 DDPKVELDERELWQQFSQCGTEMVITKSGRRIFPAYRVKISGLDKKSQYFVMMDLVPADEHRYKFNNSRWMIAGKADPEMPKTL---YIHPDSPSTGEHWMSKGANFHKLKLTNNISDKHGYTILNSMHKYQPRLHVVRCADRHNLMYSTF---RTFVFRETEFIAVTAYQNEKVTELKIENNPFAKGFRDAGAGKREK 251          
BLAST of T box transcription factor tbx2 vs. Ensembl Celegans
Match: tbx-7 (Putative T-box protein 7 [Source:UniProtKB/Swiss-Prot;Acc:Q95PX3])

HSP 1 Score: 186.422 bits (472), Expect = 8.055e-56
Identity = 105/270 (38.89%), Postives = 159/270 (58.89%), Query Frame = 1
Query:   55 FIMFLKGSHRSLRFHPYDLPYER--MPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVP 858
             ++  +G  RSL F     P++R  +P F+      + F   +++    ++ D  V  +D+P VEL ++ LW+ F    TEM+ITK GRRMFP  K+++ GLD  + Y ++++++  ++ RYK+++  WI +G  E    L + F+HP SP +GE WM+  + F   KLSN   + D  I+LNSMH+Y P+ ++VRA +           FSF ET+FIAVTAYQND +TK KI+ NPFAKGFR N    ++R   Q IS    S ++ P
Sbjct:    6 LVLMSEGYGRSL-FSEKHFPHDRQLLPPFTTTMSLGSFFSFPASSAFFDRKKDDGV--IDNPNVELVNRNLWSTFLECGTEMIITKKGRRMFPLVKLKLSGLDKNSNYTIIMEMISVDKLRYKFWNGNWIVAGVGE-HHPLPTCFVHPQSPRSGEWWMTDGVDFKMAKLSNNPFNNDGHIVLNSMHRYNPRFHIVRADSSGQPILASLKTFSFKETEFIAVTAYQNDVVTKCKIDNNPFAKGFR-NIDTVRKRKMNQIISTPPASEDEEP 270          
BLAST of T box transcription factor tbx2 vs. Ensembl Celegans
Match: tbx-7 (Putative T-box protein 7 [Source:UniProtKB/Swiss-Prot;Acc:Q95PX3])

HSP 1 Score: 186.422 bits (472), Expect = 8.055e-56
Identity = 105/270 (38.89%), Postives = 159/270 (58.89%), Query Frame = 1
Query:   55 FIMFLKGSHRSLRFHPYDLPYER--MPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVP 858
             ++  +G  RSL F     P++R  +P F+      + F   +++    ++ D  V  +D+P VEL ++ LW+ F    TEM+ITK GRRMFP  K+++ GLD  + Y ++++++  ++ RYK+++  WI +G  E    L + F+HP SP +GE WM+  + F   KLSN   + D  I+LNSMH+Y P+ ++VRA +           FSF ET+FIAVTAYQND +TK KI+ NPFAKGFR N    ++R   Q IS    S ++ P
Sbjct:    6 LVLMSEGYGRSL-FSEKHFPHDRQLLPPFTTTMSLGSFFSFPASSAFFDRKKDDGV--IDNPNVELVNRNLWSTFLECGTEMIITKKGRRMFPLVKLKLSGLDKNSNYTIIMEMISVDKLRYKFWNGNWIVAGVGE-HHPLPTCFVHPQSPRSGEWWMTDGVDFKMAKLSNNPFNNDGHIVLNSMHRYNPRFHIVRADSSGQPILASLKTFSFKETEFIAVTAYQNDVVTKCKIDNNPFAKGFR-NIDTVRKRKMNQIISTPPASEDEEP 270          
BLAST of T box transcription factor tbx2 vs. Ensembl Celegans
Match: tbx-7 (Putative T-box protein 7 [Source:UniProtKB/Swiss-Prot;Acc:Q95PX3])

HSP 1 Score: 184.882 bits (468), Expect = 1.051e-55
Identity = 93/212 (43.87%), Postives = 134/212 (63.21%), Query Frame = 1
Query:  223 LDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVP 858
            +D+P VEL ++ LW+ F    TEM+ITK GRRMFP  K+++ GLD  + Y ++++++  ++ RYK+++  WI +G  E    L + F+HP SP +GE WM+  + F   KLSN   + D  I+LNSMH+Y P+ ++VRA +           FSF ET+FIAVTAYQND +TK KI+ NPFAKGFR N    ++R   Q IS    S ++ P
Sbjct:   25 IDNPNVELVNRNLWSTFLECGTEMIITKKGRRMFPLVKLKLSGLDKNSNYTIIMEMISVDKLRYKFWNGNWIVAGVGE-HHPLPTCFVHPQSPRSGEWWMTDGVDFKMAKLSNNPFNNDGHIVLNSMHRYNPRFHIVRADSSGQPILASLKTFSFKETEFIAVTAYQNDVVTKCKIDNNPFAKGFR-NIDTVRKRKMNQIISTPPASEDEEP 234          
BLAST of T box transcription factor tbx2 vs. Ensembl Fly
Match: bi (gene:FBgn0000179 transcript:FBtr0308915)

HSP 1 Score: 226.868 bits (577), Expect = 2.030e-66
Identity = 107/197 (54.31%), Postives = 147/197 (74.62%), Query Frame = 1
Query:  223 LDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            +D P V LE K+LW +F    TEMVITK+GR+MFP  K R+ GLD  AKY+LLLDIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSPTTGE+WM K +SFHK+KL+N   DK    ILNSMHKY P+ +LVRA ++L   Y  +  + F ET+FIAVTAYQN++IT+LKI+ NPFAKGFR+  + K+E+
Sbjct:  325 VDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREK 518          
BLAST of T box transcription factor tbx2 vs. Ensembl Fly
Match: bi (gene:FBgn0000179 transcript:FBtr0343569)

HSP 1 Score: 226.868 bits (577), Expect = 2.306e-66
Identity = 107/197 (54.31%), Postives = 147/197 (74.62%), Query Frame = 1
Query:  223 LDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            +D P V LE K+LW +F    TEMVITK+GR+MFP  K R+ GLD  AKY+LLLDIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSPTTGE+WM K +SFHK+KL+N   DK    ILNSMHKY P+ +LVRA ++L   Y  +  + F ET+FIAVTAYQN++IT+LKI+ NPFAKGFR+  + K+E+
Sbjct:  325 VDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREK 518          
BLAST of T box transcription factor tbx2 vs. Ensembl Fly
Match: bi (gene:FBgn0000179 transcript:FBtr0300608)

HSP 1 Score: 224.942 bits (572), Expect = 1.147e-65
Identity = 108/202 (53.47%), Postives = 149/202 (73.76%), Query Frame = 1
Query:  223 LDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVI---ILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQ 813
            +D P V LE K+LW +F    TEMVITK+GR+MFP  K R+ GLD  AKY+LLLDIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSPTTGE+WM K +SFHK+KL+N   DK   +   ILNSMHKY P+ +LVRA ++L   Y  +  + F ET+FIAVTAYQN++IT+LKI+ NPFAKGFR+  + K+E+ Q
Sbjct:  325 VDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREKKQ 523          
BLAST of T box transcription factor tbx2 vs. Ensembl Fly
Match: bi (gene:FBgn0000179 transcript:FBtr0070672)

HSP 1 Score: 224.942 bits (572), Expect = 1.147e-65
Identity = 108/202 (53.47%), Postives = 149/202 (73.76%), Query Frame = 1
Query:  223 LDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVI---ILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQ 813
            +D P V LE K+LW +F    TEMVITK+GR+MFP  K R+ GLD  AKY+LLLDIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSPTTGE+WM K +SFHK+KL+N   DK   +   ILNSMHKY P+ +LVRA ++L   Y  +  + F ET+FIAVTAYQN++IT+LKI+ NPFAKGFR+  + K+E+ Q
Sbjct:  325 VDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREKKQ 523          
BLAST of T box transcription factor tbx2 vs. Ensembl Fly
Match: bi (gene:FBgn0000179 transcript:FBtr0300609)

HSP 1 Score: 224.942 bits (572), Expect = 1.147e-65
Identity = 108/202 (53.47%), Postives = 149/202 (73.76%), Query Frame = 1
Query:  223 LDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVI---ILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQ 813
            +D P V LE K+LW +F    TEMVITK+GR+MFP  K R+ GLD  AKY+LLLDIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSPTTGE+WM K +SFHK+KL+N   DK   +   ILNSMHKY P+ +LVRA ++L   Y  +  + F ET+FIAVTAYQN++IT+LKI+ NPFAKGFR+  + K+E+ Q
Sbjct:  325 VDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREKKQ 523          
BLAST of T box transcription factor tbx2 vs. Ensembl Zebrafish
Match: tbx3b (T-box transcription factor 3b [Source:ZFIN;Acc:ZDB-GENE-060531-144])

HSP 1 Score: 227.639 bits (579), Expect = 9.181e-69
Identity = 107/196 (54.59%), Postives = 148/196 (75.51%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D PVV LE  ELW +F    TEMVITK+GRRMFP+FKVR  G D  A+Y+LL+DIV S++ RYK+++ +W+ +GKA  E+ + +   +IHPDSP+TGE+WMSK+++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+FIAVTAYQN++IT+LKI+ NPFAKGFRE  + ++E+
Sbjct:   70 DEPVVHLEGNELWGQFHKVGTEMVITKSGRRMFPAFKVRCSGFDRKARYILLMDIVASDDYRYKFHNCRWMVAGKADPEMPKRM---YIHPDSPSTGEQWMSKAVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDVLKLPYSTFKTYVFPETEFIAVTAYQNEKITQLKIDNNPFAKGFRETGNGRREK 262          
BLAST of T box transcription factor tbx2 vs. Ensembl Zebrafish
Match: tbx2a (T-box transcription factor 2a [Source:ZFIN;Acc:ZDB-GENE-990917-4])

HSP 1 Score: 228.409 bits (581), Expect = 2.373e-68
Identity = 107/196 (54.59%), Postives = 147/196 (75.00%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F    TEMVITK+GRRMFP FKVR+ GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:   91 DDPKVTLEAKELWDQFHKIGTEMVITKSGRRMFPPFKVRVNGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 283          
BLAST of T box transcription factor tbx2 vs. Ensembl Zebrafish
Match: tbx2a (T-box transcription factor 2a [Source:ZFIN;Acc:ZDB-GENE-990917-4])

HSP 1 Score: 228.409 bits (581), Expect = 2.383e-68
Identity = 107/196 (54.59%), Postives = 147/196 (75.00%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F    TEMVITK+GRRMFP FKVR+ GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:   81 DDPKVTLEAKELWDQFHKIGTEMVITKSGRRMFPPFKVRVNGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 273          
BLAST of T box transcription factor tbx2 vs. Ensembl Zebrafish
Match: tbx3a (T-box transcription factor 3a [Source:ZFIN;Acc:ZDB-GENE-070209-80])

HSP 1 Score: 226.483 bits (576), Expect = 1.731e-67
Identity = 106/192 (55.21%), Postives = 145/192 (75.52%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            V LE KELW  F  + TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI++NPFAKGFR+  + ++E+
Sbjct:  100 VHLEAKELWELFHKRGTEMVITKSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVNFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDHNPFAKGFRDTGNGRREK 288          
BLAST of T box transcription factor tbx2 vs. Ensembl Zebrafish
Match: tbx2b (T-box transcription factor 2b [Source:NCBI gene;Acc:30253])

HSP 1 Score: 225.328 bits (573), Expect = 3.615e-67
Identity = 117/251 (46.61%), Postives = 163/251 (64.94%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKS 984
            V LE K+LW +F    TEMVITK+GRRMFP FKVRI GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+ +      T PS         V ++    + S  +    R    SP P    P  FN+ 
Sbjct:   96 VTLEAKDLWDQFHKLGTEMVITKSGRRMFPPFKVRINGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRK----QLTLPSLRMYEDQCKVDRDGADSDASSSEPTTGRDAGHSPGPVS-SPLRFNRG 338          
BLAST of T box transcription factor tbx2 vs. Ensembl Xenopus
Match: tbx3 (T-box 3 [Source:NCBI gene;Acc:613116])

HSP 1 Score: 228.794 bits (582), Expect = 3.766e-68
Identity = 106/203 (52.22%), Postives = 150/203 (73.89%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKP 840
            V LE K+LW +F  + TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+ +   +   +P
Sbjct:  106 VHLEGKDLWEQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLALQSMRP 305          
BLAST of T box transcription factor tbx2 vs. Ensembl Xenopus
Match: tbx2 (T-box 2 [Source:NCBI gene;Acc:619588])

HSP 1 Score: 227.639 bits (579), Expect = 6.821e-68
Identity = 105/192 (54.69%), Postives = 145/192 (75.52%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            V LE KELW +F    TEMVITK+GRRMFP FKVR+ GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:   97 VTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 285          
BLAST of T box transcription factor tbx2 vs. Ensembl Xenopus
Match: vegt (vegt protein [Source:NCBI gene;Acc:394452])

HSP 1 Score: 196.438 bits (498), Expect = 2.493e-58
Identity = 95/185 (51.35%), Postives = 130/185 (70.27%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSP---FIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRE 783
              LED++LW +F  + TEM+ITK+GRRMFP  K+R+ GL P AKY+LL+D V  +  RYK+  NQW  +GKAE     H P   ++HPDSP  G  WM  +I F K+KL+N  +D+   IIL+SMH+Y P+ ++V++ ++  + +     FSF ET+F AVTAYQN++ITKLKIN+NPFAKGFRE
Sbjct:   30 ASLEDQDLWAQFHQEGTEMIITKSGRRMFPQCKIRLFGLHPYAKYMLLVDFVPLDNFRYKWNKNQWEAAGKAEP----HPPCRTYVHPDSPAPGAHWMKDAICFQKLKLTNNTLDQQGHIILHSMHRYKPRFHVVQSDDMYNSPWGLVQVFSFPETEFTAVTAYQNEKITKLKINHNPFAKGFRE 210          
BLAST of T box transcription factor tbx2 vs. Ensembl Xenopus
Match: vegt (vegt protein [Source:NCBI gene;Acc:394452])

HSP 1 Score: 196.823 bits (499), Expect = 2.605e-58
Identity = 95/185 (51.35%), Postives = 130/185 (70.27%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSP---FIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRE 783
              LED++LW +F  + TEM+ITK+GRRMFP  K+R+ GL P AKY+LL+D V  +  RYK+  NQW  +GKAE     H P   ++HPDSP  G  WM  +I F K+KL+N  +D+   IIL+SMH+Y P+ ++V++ ++  + +     FSF ET+F AVTAYQN++ITKLKIN+NPFAKGFRE
Sbjct:   30 ASLEDQDLWAQFHQEGTEMIITKSGRRMFPQCKIRLFGLHPYAKYMLLVDFVPLDNFRYKWNKNQWEAAGKAEP----HPPCRTYVHPDSPAPGAHWMKDAICFQKLKLTNNTLDQQGHIILHSMHRYKPRFHVVQSDDMYNSPWGLVQVFSFPETEFTAVTAYQNEKITKLKINHNPFAKGFRE 210          
BLAST of T box transcription factor tbx2 vs. Ensembl Xenopus
Match: vegt (vegt protein [Source:NCBI gene;Acc:394452])

HSP 1 Score: 196.438 bits (498), Expect = 3.139e-58
Identity = 95/185 (51.35%), Postives = 130/185 (70.27%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSP---FIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRE 783
              LED++LW +F  + TEM+ITK+GRRMFP  K+R+ GL P AKY+LL+D V  +  RYK+  NQW  +GKAE     H P   ++HPDSP  G  WM  +I F K+KL+N  +D+   IIL+SMH+Y P+ ++V++ ++  + +     FSF ET+F AVTAYQN++ITKLKIN+NPFAKGFRE
Sbjct:   33 ASLEDQDLWAQFHQEGTEMIITKSGRRMFPQCKIRLFGLHPYAKYMLLVDFVPLDNFRYKWNKNQWEAAGKAEP----HPPCRTYVHPDSPAPGAHWMKDAICFQKLKLTNNTLDQQGHIILHSMHRYKPRFHVVQSDDMYNSPWGLVQVFSFPETEFTAVTAYQNEKITKLKINHNPFAKGFRE 213          
BLAST of T box transcription factor tbx2 vs. Ensembl Mouse
Match: Tbx3 (T-box 3 [Source:MGI Symbol;Acc:MGI:98495])

HSP 1 Score: 231.876 bits (590), Expect = 2.947e-69
Identity = 107/196 (54.59%), Postives = 148/196 (75.51%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F  + TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DI+ +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  101 DDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 293          
BLAST of T box transcription factor tbx2 vs. Ensembl Mouse
Match: Tbx3 (T-box 3 [Source:MGI Symbol;Acc:MGI:98495])

HSP 1 Score: 231.876 bits (590), Expect = 2.947e-69
Identity = 107/196 (54.59%), Postives = 148/196 (75.51%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F  + TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DI+ +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  101 DDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 293          
BLAST of T box transcription factor tbx2 vs. Ensembl Mouse
Match: Tbx2 (T-box 2 [Source:MGI Symbol;Acc:MGI:98494])

HSP 1 Score: 231.106 bits (588), Expect = 3.675e-69
Identity = 107/196 (54.59%), Postives = 147/196 (75.00%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F    TEMVITK+GRRMFP FKVR+ GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  103 DDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 295          
BLAST of T box transcription factor tbx2 vs. Ensembl Mouse
Match: Tbx3 (T-box 3 [Source:MGI Symbol;Acc:MGI:98495])

HSP 1 Score: 219.55 bits (558), Expect = 1.585e-64
Identity = 107/216 (49.54%), Postives = 148/216 (68.52%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDV--------------------IILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F  + TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DI+ +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK                        ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  101 DDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 313          
BLAST of T box transcription factor tbx2 vs. Ensembl Mouse
Match: Tbx6 (T-box 6 [Source:MGI Symbol;Acc:MGI:102539])

HSP 1 Score: 204.142 bits (518), Expect = 2.763e-61
Identity = 100/201 (49.75%), Postives = 136/201 (67.66%), Query Frame = 1
Query:  214 VRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENC-SLKKER 807
            + SL    + LE++ELW EF    TEM+ITK GRRMFP+ +V + GLDP A+Y+ LLD+V  +  RY++    W  SGKAE  +   +   +IHPDSP TG  WM + +SFH++KL+N+ +D    +IL+SMHKY P+++LVRA  L   ++     F F ET FI+VTAYQN +IT+LKI  NPFAKGFREN  + K+ER
Sbjct:   85 LHSLPGVSLSLENQELWKEFSAVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVVPVDGARYRWQGQHWEPSGKAEPRLPDRV---YIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRATQLCSQHWGGVASFRFPETTFISVTAYQNPRITQLKIAANPFAKGFRENGRNCKRER 282          
BLAST of T box transcription factor tbx2 vs. UniProt/SwissProt
Match: sp|Q6PCL0|TBX2B_XENLA (T-box transcription factor TBX2-B OS=Xenopus laevis OX=8355 GN=tbx2-b PE=2 SV=2)

HSP 1 Score: 233.032 bits (593), Expect = 3.419e-69
Identity = 114/237 (48.10%), Postives = 159/237 (67.09%), Query Frame = 1
Query:  133 FSRPWLKQNSFDDISTNVLAAQQYDWRVRSL----------DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
             S P L   +   +  + L        +RSL          D P V LE KELW +F    TEMVITK+GRRMFP FKVR+ GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI++NPFAKGFR+  + ++E+
Sbjct:   52 LSDPSLAGAAEAGLHLSALGHHHQAAHLRSLKSLEPEEEVDDDPKVNLEAKELWDQFHKIGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDHNPFAKGFRDTGNGRREK 285          
BLAST of T box transcription factor tbx2 vs. UniProt/SwissProt
Match: sp|O73718|TBX3_CHICK (T-box transcription factor TBX3 (Fragment) OS=Gallus gallus OX=9031 GN=TBX3 PE=2 SV=1)

HSP 1 Score: 225.713 bits (574), Expect = 5.157e-69
Identity = 106/192 (55.21%), Postives = 146/192 (76.04%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            V LE KELW +F  + TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  107 VHLEAKELWEQFHKRGTEMVITKSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 295          
BLAST of T box transcription factor tbx2 vs. UniProt/SwissProt
Match: sp|Q13207|TBX2_HUMAN (T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3)

HSP 1 Score: 232.261 bits (591), Expect = 9.832e-69
Identity = 107/196 (54.59%), Postives = 147/196 (75.00%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F    TEMVITK+GRRMFP FKVR+ GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  103 DDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 295          
BLAST of T box transcription factor tbx2 vs. UniProt/SwissProt
Match: sp|Q863A2|TBX2_CANLF (T-box transcription factor TBX2 OS=Canis lupus familiaris OX=9615 GN=TBX2 PE=3 SV=2)

HSP 1 Score: 232.261 bits (591), Expect = 1.288e-68
Identity = 107/196 (54.59%), Postives = 147/196 (75.00%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F    TEMVITK+GRRMFP FKVR+ GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  103 DDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 295          
BLAST of T box transcription factor tbx2 vs. UniProt/SwissProt
Match: sp|Q60707|TBX2_MOUSE (T-box transcription factor TBX2 OS=Mus musculus OX=10090 GN=Tbx2 PE=1 SV=3)

HSP 1 Score: 231.106 bits (588), Expect = 2.570e-68
Identity = 107/196 (54.59%), Postives = 147/196 (75.00%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE KELW +F    TEMVITK+GRRMFP FKVR+ GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:  103 DDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 295          
BLAST of T box transcription factor tbx2 vs. TrEMBL
Match: A0A5P8I4J1 (T-box 2/3b protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 332/332 (100.00%), Postives = 332/332 (100.00%), Query Frame = 1
Query:   61 MFLKGSHRSLRFHPYDLPYERMPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC 1056
            MFLKGSHRSLRFHPYDLPYERMPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC
Sbjct:    1 MFLKGSHRSLRFHPYDLPYERMPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC 332          
BLAST of T box transcription factor tbx2 vs. TrEMBL
Match: F1CDE9 (TBX2/3b (Fragment) OS=Schmidtea polychroa OX=50054 PE=2 SV=1)

HSP 1 Score: 333.569 bits (854), Expect = 4.200e-112
Identity = 161/165 (97.58%), Postives = 161/165 (97.58%), Query Frame = 1
Query:  562 TRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC 1056
            TRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQ QNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRP EYQ AIFNKSD TSIEKRETPDQNKKPKQGFLIC
Sbjct:    1 TRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQSQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPLEYQSAIFNKSDTTSIEKRETPDQNKKPKQGFLIC 165          
BLAST of T box transcription factor tbx2 vs. TrEMBL
Match: A0A087W231 (T box transcription factor tbx2 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000247100 PE=4 SV=1)

HSP 1 Score: 249.98 bits (637), Expect = 4.177e-73
Identity = 116/216 (53.70%), Postives = 161/216 (74.54%), Query Frame = 1
Query:  196 QQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDV-IILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKP 840
            Q+ +  ++  D P  EL + ELW  F   TTEMVITK+GRRMFP++KV + GLDP AKYV+L+DIV  +ENRYK+++N W  +GKA+  +    P+IHPDSP TGE+WM K ISFHK+KL+N   ++     +LNSMHKYIP++++VRA +L+  N+C +  FSF E++FIAVTAYQN+QIT+LKI++NPFAKGFR+N S ++E+ + Q + Q  P
Sbjct:  195 QEEEAEIKKHDCPKAELAEPELWRAFHKMTTEMVITKSGRRMFPAYKVNVSGLDPKAKYVMLMDIVPRDENRYKFHNNGWAVAGKAD-PEPTKRPYIHPDSPATGEQWMQKPISFHKLKLTNNITERQPFQAVLNSMHKYIPRVHIVRADDLMKINFCEFVTFSFEESEFIAVTAYQNEQITQLKIDHNPFAKGFRDNGSGRREKKR-QRLQQLPP 408          
BLAST of T box transcription factor tbx2 vs. TrEMBL
Match: A0A068WJM5 (T box transcription factor tbx2 OS=Echinococcus granulosus OX=6210 GN=EgrG_000247100 PE=4 SV=1)

HSP 1 Score: 249.98 bits (637), Expect = 4.260e-73
Identity = 116/216 (53.70%), Postives = 161/216 (74.54%), Query Frame = 1
Query:  196 QQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDV-IILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKP 840
            Q+ +  ++  D P  EL + ELW  F   TTEMVITK+GRRMFP++KV + GLDP AKYV+L+DIV  +ENRYK+++N W  +GKA+  +    P+IHPDSP TGE+WM K ISFHK+KL+N   ++     +LNSMHKYIP++++VRA +L+  N+C +  FSF E++FIAVTAYQN+QIT+LKI++NPFAKGFR+N S ++E+ + Q + Q  P
Sbjct:  196 QEEEAEIKKHDCPKAELAEPELWRAFHKMTTEMVITKSGRRMFPAYKVNVSGLDPKAKYVMLMDIVPRDENRYKFHNNGWAVAGKAD-PEPTKRPYIHPDSPATGEQWMQKPISFHKLKLTNNITERQPFQAVLNSMHKYIPRVHIVRADDLMKINFCEFVTFSFEESEFIAVTAYQNEQITQLKIDHNPFAKGFRDNGSGRREKKR-QRLQQLPP 409          
BLAST of T box transcription factor tbx2 vs. TrEMBL
Match: A0A0R3WBU1 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS8126 PE=4 SV=2)

HSP 1 Score: 249.595 bits (636), Expect = 4.537e-73
Identity = 117/226 (51.77%), Postives = 165/226 (73.01%), Query Frame = 1
Query:  196 QQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDV-IILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKE--RSQPQNISQTKPSPNQVPSD 864
            Q+ +  ++  D P  EL + ELW  F   TTEMVITK+GRRMFP++K+ + GLDP AKYV+L+DIV  +ENRYK+++N W  +GKA+  +    P+IHPDSP TGE+WM K ISFHK+KL+N   ++     +LNSMHKYIP++++VRA +L+  N+C +  FSF E++FIAVTAYQN+QIT+LKI++NPFAKGFR+N S ++E  R + Q + Q   + + +P D
Sbjct:  196 QEEEAEIKKHDCPKAELAEPELWRAFHKMTTEMVITKSGRRMFPAYKINVSGLDPKAKYVMLMDIVPRDENRYKFHNNGWAVAGKAD-PEPTKRPYIHPDSPATGEQWMQKPISFHKLKLTNNIAERQPFQAVLNSMHKYIPRVHIVRADDLMKINFCEFVTFSFEESEFIAVTAYQNEQITQLKIDHNPFAKGFRDNGSGRREKKRQRLQQLPQLNSTGSLIPED 420          
BLAST of T box transcription factor tbx2 vs. Ensembl Cavefish
Match: tbx2b (T-box transcription factor 2 [Source:NCBI gene;Acc:103034102])

HSP 1 Score: 226.098 bits (575), Expect = 1.785e-67
Identity = 105/192 (54.69%), Postives = 146/192 (76.04%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            V LE K+LW +F    TEMVITK+GRRMFP FKVRI GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+FIAVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:   95 VTLEAKDLWDQFHKLGTEMVITKSGRRMFPPFKVRINGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 283          
BLAST of T box transcription factor tbx2 vs. Ensembl Cavefish
Match: tbx3a (T-box transcription factor 3 [Source:NCBI gene;Acc:103021647])

HSP 1 Score: 224.557 bits (571), Expect = 7.799e-67
Identity = 106/192 (55.21%), Postives = 144/192 (75.00%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            V LE KELW  F    TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI++NPFAKGFR+  + ++E+
Sbjct:  108 VHLEAKELWELFHKCGTEMVITKSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVNFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDHNPFAKGFRDTGNGRREK 296          
BLAST of T box transcription factor tbx2 vs. Ensembl Cavefish
Match: tbx5b (T-box transcription factor TBX5-like [Source:NCBI gene;Acc:103031023])

HSP 1 Score: 198.749 bits (504), Expect = 8.997e-60
Identity = 102/209 (48.80%), Postives = 140/209 (66.99%), Query Frame = 1
Query:  193 AQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRA--QNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            A  +  +++ L+   V L ++ELW +F   TTEM+ITK GRRMFPS+KV++ GL P AKY+LL+DIV ++E+RYK+  N+W   GKAE  I   L   ++HPDSP  G  W  + +SF K+KL+N  +D    IILNSMHKY P+L++V+A  +N   ++   +   SF ET FIAVT+YQN  IT+LKI  NPFAKGFR N  ++  R
Sbjct:    2 ADGFQEQLQGLEGVKVHLHERELWRKFHEVTTEMIITKAGRRMFPSYKVKVTGLHPKAKYILLMDIVAADEHRYKFADNKWSVCGKAEPAIPGRL---YVHPDSPAPGAHWTRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADEKNSFGSSNTAFCTHSFPETAFIAVTSYQNHTITQLKIENNPFAKGFRGNEEIEMHR 207          
BLAST of T box transcription factor tbx2 vs. Ensembl Cavefish
Match: tbx5b (T-box transcription factor TBX5-like [Source:NCBI gene;Acc:103031023])

HSP 1 Score: 196.438 bits (498), Expect = 1.216e-58
Identity = 101/202 (50.00%), Postives = 136/202 (67.33%), Query Frame = 1
Query:  214 VRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRA--QNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
             + L+   V L ++ELW +F   TTEM+ITK GRRMFPS+KV++ GL P AKY+LL+DIV ++E+RYK+  N+W   GKAE  I   L   ++HPDSP  G  W  + +SF K+KL+N  +D    IILNSMHKY P+L++V+A  +N   ++   +   SF ET FIAVT+YQN  IT+LKI  NPFAKGFR N  ++  R
Sbjct:   44 TQGLEGVKVHLHERELWRKFHEVTTEMIITKAGRRMFPSYKVKVTGLHPKAKYILLMDIVAADEHRYKFADNKWSVCGKAEPAIPGRL---YVHPDSPAPGAHWTRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADEKNSFGSSNTAFCTHSFPETAFIAVTSYQNHTITQLKIENNPFAKGFRGNEEIEMHR 242          
BLAST of T box transcription factor tbx2 vs. Ensembl Cavefish
Match: tbx6 (T-box transcription factor 6 [Source:NCBI gene;Acc:192294])

HSP 1 Score: 203.756 bits (517), Expect = 2.973e-58
Identity = 99/204 (48.53%), Postives = 141/204 (69.12%), Query Frame = 1
Query:  205 DWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENC-SLKKER 807
            D   R+LD   +ELE+  LW +F    TEM+ITK GRRMFP  ++++ GL+P+ +Y+LLLDIV  + +RY++  + W   G AE  +   +   FIHPDSP TGE W +++ISFH+ KL+N  +D    IIL+S+HKY P+++++ A+++L         F+F ETQFI VTAYQN++IT+LKIN NPFAKGFREN  + KK+R
Sbjct:   34 DMMARTLDTVKMELENASLWKQFSTVGTEMIITKKGRRMFPQLRLKLSGLNPSLRYILLLDIVPVDSSRYRFQDDSWQVVGGAEARLPDRV---FIHPDSPATGEHWQNRTISFHRAKLTNNTLDMQGHIILHSLHKYQPRVHVIEARDVLMWGGAQH-SFTFPETQFITVTAYQNNRITELKINSNPFAKGFRENGMNCKKQR 233          
BLAST of T box transcription factor tbx2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004087.1 (pep scaffold:Pmarinus_7.0:GL483204:5206:18999:-1 gene:ENSPMAG00000003745.1 transcript:ENSPMAT00000004087.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 158.688 bits (400), Expect = 8.983e-48
Identity = 83/173 (47.98%), Postives = 118/173 (68.21%), Query Frame = 1
Query:  286 TEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKY-YH-NQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVR----AQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFR 780
            TEM+ITK+GRRMFP+ +V   G++P AKY++L+DIV  +  RY+Y YH + W+ +GKA+  +   L   ++HPDSP  GE+   + +SF K+KL+N  +D+   IILNSMHKY P++++++      +L+      +  F F ET F AVTAYQN  ITKLKI+ NPFAKGFR
Sbjct:    5 TEMIITKSGRRMFPTIRVSFGGVEPDAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARL---YVHPDSPFAGEQLHKQMVSFEKLKLTNNELDQHGHIILNSMHKYQPRVHIIKKMDHTSSLVNLKSEEFRTFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFR 174          
BLAST of T box transcription factor tbx2 vs. Ensembl Sea Lamprey
Match: TBR1 (T-box brain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11590])

HSP 1 Score: 167.933 bits (424), Expect = 3.059e-47
Identity = 88/225 (39.11%), Postives = 133/225 (59.11%), Query Frame = 1
Query:  241 ELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDD---VIILNSMHKYIPKLYLVRAQNLLY---TNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFREN-----CSLKKERSQPQNISQTKPSPNQVPSDYAVMKN 882
            +L ++ LW +F    T  +IT+ G RMFP     + GLDPTA Y + +D+VL++ N +++   +W+  GKA+ +   +  ++HPDSP TG  WM + ISF K+KL+N +   ++   +I+L S+HKY P+L++V          T       F+F ETQFIAVTAYQN  IT+LKI++NPFAKGFR+N       L  +R          PSP+ VP  ++++  
Sbjct:  115 DLCNRALWIKFHRHFTNRLITRVGMRMFPFLSFTVSGLDPTAHYNIFVDVVLADPNHWRFQGGKWVPCGKADTNVQGNRMYLHPDSPNTGAHWMRQEISFGKLKLTNNKGGTNNTGQMIVLQSLHKYQPRLHVVEVNEEGVEDATQPGRAQTFTFPETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYPGLDADR--------LTPSPHDVPRHHSLLGG 331          
BLAST of T box transcription factor tbx2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008915.1 (pep scaffold:Pmarinus_7.0:GL481372:6049:9031:1 gene:ENSPMAG00000008071.1 transcript:ENSPMAT00000008915.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 138.272 bits (347), Expect = 8.355e-40
Identity = 79/186 (42.47%), Postives = 110/186 (59.14%), Query Frame = 1
Query:  235 VVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKY--YHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWD-EFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRE 783
               L++ ELW +F    TEM+ITK+G +        +  L P  + +   ++V ++E +YK+     +W  SG AE+S      ++HP SP++G +WM + +SFHK KL+N  + K   +IL+SMHKY P  Y+VR  +       H    FSF +T FIAVTAYQN  ITKLKI  NPFAKGFRE
Sbjct:    2 AATLDNAELWRKFHAIGTEMIITKSGSKW-------VIALSPRGRQIKX-ELVPADEVKYKWREAEERWEASGPAELSMPSRL-YVHPSSPSSGAQWMRQPVSFHKAKLTNNALSKSGHLILHSMHKYQPCFYVVRDTDWRGVAAAHSPLTFSFPDTTFIAVTAYQNSLITKLKIATNPFAKGFRE 178          
BLAST of T box transcription factor tbx2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007664.1 (pep scaffold:Pmarinus_7.0:GL477495:60408:67857:-1 gene:ENSPMAG00000006925.1 transcript:ENSPMAT00000007664.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 142.51 bits (358), Expect = 1.878e-37
Identity = 71/182 (39.01%), Postives = 116/182 (63.74%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQW--IKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNL---LYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFA 768
            V L+++E+W  F +  TEM++TKTGRRMFP  + +++GLDP + Y++ +D+V  + +RY++    W  I+ GK +I   +   ++H +    G  WM +SISF ++KL+NT + +D VI L  M KY+ + +++RA  +   L  +  +   F F +T+F AVTAYQN  IT LKI+++P A
Sbjct:    4 VTLDNREVWERFHSWGTEMILTKTGRRMFPYCRYKVRGLDPQSCYLMAIDVVPVDGHRYRWGEGCWMPIERGKPQIPDSV---YVHQEGVAPGSFWMYESISFSEVKLTNTALGQDGVISLIPMFKYVTRFHIIRANKVPRHLRLDADNVHTFIFPQTEFFAVTAYQNTAITHLKISHSPLA 182          
BLAST of T box transcription factor tbx2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004398.1 (pep scaffold:Pmarinus_7.0:GL481394:165233:166024:1 gene:ENSPMAG00000004017.1 transcript:ENSPMAT00000004398.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.3445 bits (207), Expect = 3.129e-20
Identity = 36/76 (47.37%), Postives = 55/76 (72.37%), Query Frame = 1
Query:  235 VVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKY-YHNQ-WIKSGKAE 456
               LE KELW +F    TEM+ITK+GRRMFP+ +V + G++P A+Y++L+DI+  ++ RY+Y YH   W+ +GKA+
Sbjct:   43 ACALETKELWDKFHELGTEMIITKSGRRMFPTIRVSLSGVEPDARYIVLMDIIPVDQKRYRYAYHRSCWLVAGKAD 118          
BLAST of T box transcription factor tbx2 vs. Ensembl Nematostella
Match: EDO41888 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S327])

HSP 1 Score: 203.371 bits (516), Expect = 1.609e-64
Identity = 103/194 (53.09%), Postives = 139/194 (71.65%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSP-FIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLL-YTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQ 813
            + L++K+LW  F  + TEMVITK GRRMFP  K RI GLDP AKY  LLDI+ +++ RYK+++ +W+ +GKA+    L  P +IHPDSP+TG +WM K+ISFHK+KL+N   DK    ILNSMHKY P++++VRA +   Y     +  F+F ET FIAVTAYQN++IT+LKI+ NPFAKGFRE  +  + R +
Sbjct:    6 ILLDNKDLWQSFHAEKTEMVITKAGRRMFPPIKARISGLDPRAKYFFLLDIIPADDCRYKFHNCRWMVAGKAD--PELDKPLYIHPDSPSTGTQWMQKTISFHKMKLTNNIADKHGYTILNSMHKYQPRIHIVRADDGYKYPLNQPFKTFTFPETTFIAVTAYQNEKITQLKIDNNPFAKGFREEGAGHRRRME 197          
BLAST of T box transcription factor tbx2 vs. Ensembl Nematostella
Match: EDO41889 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S328])

HSP 1 Score: 194.126 bits (492), Expect = 1.666e-60
Identity = 96/189 (50.79%), Postives = 131/189 (69.31%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQ--NLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCS 792
            VELE++ELW +F    TEM+ITK GRRMFP  +V I GL+P  +YVL +D+V ++ENRYKY++ +W  +GKAE  I   +   FIHPDSP TG +WM + ISF K+KL+N   D+   +ILNSMHKY P+++++  +  N+       +  + F ET F+AVTAYQN +IT+LKI  NPFAKGFR  C+
Sbjct:   35 VELENRELWEKFHEIGTEMIITKNGRRMFPVIRVNISGLNPKEEYVLAMDLVPADENRYKYHNTEWAITGKAENLIPSRI---FIHPDSPGTGSQWMRQVISFQKLKLTNNHNDQAGHVILNSMHKYQPRIHIIPTKDYNVFSMKKGTFYTYQFQETTFMAVTAYQNPRITQLKIENNPFAKGFRGGCN 220          
BLAST of T box transcription factor tbx2 vs. Ensembl Nematostella
Match: EDO35074 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMK3])

HSP 1 Score: 193.356 bits (490), Expect = 2.801e-58
Identity = 98/200 (49.00%), Postives = 136/200 (68.00%), Query Frame = 1
Query:  217 RSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKY--YHNQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLV-------RAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRE 783
            R L H  VELE K LW EF +  TEM++TK GRRMFP+F+VR+ GL+P+AK++L++D V  ++ RY+Y  + ++W+ +GKA+  +   +H   IHPDSP TG +WM + +SF K+KL+N  +D +  IILNSMHKY P+ +++          +L   +  H   F F ETQF+AVTAYQN  IT+LKI  NPFAKGFRE
Sbjct:   17 RCLAHVRVELEMKSLWDEFHSLGTEMIVTKAGRRMFPTFQVRLYGLEPSAKHILMMDFVPVDDKRYRYAFHSSKWLVAGKADPSVPGRVH---IHPDSPCTGAQWMKQIVSFDKLKLTNNLMDDNGHIILNSMHKYQPRFHVILEDPDRSSTASLHEVSKDHIRTFIFPETQFMAVTAYQNHMITQLKIASNPFAKGFRE 213          
BLAST of T box transcription factor tbx2 vs. Ensembl Nematostella
Match: EDO35086 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMK2])

HSP 1 Score: 180.644 bits (457), Expect = 1.177e-55
Identity = 92/188 (48.94%), Postives = 126/188 (67.02%), Query Frame = 1
Query:  253 KELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKY--YHNQWIKSGKAE--ISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRA-------QNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRE 783
            K LW EF+   TEM++TK GRRMFP F+VR+ GL+P  KY+L++D V  ++ RY+Y  + ++W+ +GKA+  +   +H   IHPDSP TG +WM + +SF K+KL+N  +D +  IILNSMHKY P+ ++V          NL   N  H   F F E+QF+AVTAYQN  IT+LKI  NPFAKGFR+
Sbjct:    2 KNLWDEFYTLGTEMIVTKAGRRMFPPFQVRLYGLEPNVKYILMMDFVPVDDKRYRYAFHSSKWLVAGKADPSVPGRVH---IHPDSPCTGAQWMKQIVSFDKLKLTNNLMDDNGHIILNSMHKYQPRFHVVLVTSDKNANANLNDVNRDHIKTFVFPESQFMAVTAYQNHMITQLKIASNPFAKGFRD 186          
BLAST of T box transcription factor tbx2 vs. Ensembl Nematostella
Match: EDO46664 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPC8])

HSP 1 Score: 178.333 bits (451), Expect = 7.857e-55
Identity = 90/197 (45.69%), Postives = 132/197 (67.01%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKY-YHN-QWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWD---------EFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSL 795
            VEL+  +LW  F+   TEM+ITK GRRMFP+ +V++ GLD  A Y+L++D++  +  RY+Y YH+ +W+ +G A+ +      +IHPDSP  GEEWM + +SF K+KL+N  +D+   IIL+SMHKY P+++++R ++   T+    D          F+F ET F  VTAYQN QIT+LKI+ NPFAKGFR++  L
Sbjct:    3 VELQMHDLWRRFYELGTEMIITKAGRRMFPAIRVKVSGLDLHAHYILVMDVIPLDGKRYRYAYHSSKWVVAGNAD-APMPGRVYIHPDSPALGEEWMRQIVSFDKVKLTNNELDQQGHIILHSMHKYQPRIHIIRKKD---TSEASIDIDRPCSERKTFTFSETVFTTVTAYQNQQITRLKIDSNPFAKGFRDSGRL 195          
BLAST of T box transcription factor tbx2 vs. Ensembl Medaka
Match: TBX2 (T-box transcription factor 2 [Source:NCBI gene;Acc:100049371])

HSP 1 Score: 229.565 bits (584), Expect = 7.301e-69
Identity = 106/196 (54.08%), Postives = 148/196 (75.51%), Query Frame = 1
Query:  226 DHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            D P V LE K+LW +F    TEMVITK+GRRMFP FKVRI GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WM+K ++FHK+KL+N   DK    ILNSMHKY P+ ++VRA ++L   Y  +  + F ET+F+AVTAYQND+IT+LKI+ NPFAKGFR+  + ++E+
Sbjct:   91 DDPKVTLEAKDLWDQFHKLGTEMVITKSGRRMFPPFKVRINGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETEFVAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREK 283          
BLAST of T box transcription factor tbx2 vs. Ensembl Medaka
Match: tbx3a (T-box transcription factor 3 [Source:NCBI gene;Acc:100049473])

HSP 1 Score: 222.631 bits (566), Expect = 5.758e-66
Identity = 107/197 (54.31%), Postives = 146/197 (74.11%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVI-----ILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            V LE KELW  F  K TEMVITK+GRRMFP FKVR  GLD  AKY+LL+DIV +++ RYK+++++W+ +GKA  E+ + +   +IHPDSP TGE+WMSK ++FHK+KL+N   DK   +     ILNSMHKY P+ ++VRA ++L   Y  +  + F ET FIAVTAYQND+IT+LKI++NPFAKGFR+  + ++E+
Sbjct:  106 VHLEAKELWELFHKKGTEMVITKSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRM---YIHPDSPATGEQWMSKVVNFHKLKLTNNISDKHGFVSSTNTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDHNPFAKGFRDTGNGRREK 299          
BLAST of T box transcription factor tbx2 vs. Ensembl Medaka
Match: tbx4 (T-box transcription factor 4 [Source:NCBI gene;Acc:101172998])

HSP 1 Score: 196.052 bits (497), Expect = 3.190e-57
Identity = 96/196 (48.98%), Postives = 135/196 (68.88%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRA--QNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFR--ENCSLKKERSQ 813
            V L ++ELW  F    TEM+ITK GRRMFPS+KV++ G++P  KY+LL+DIV ++++RYK+  N+W+ +GKAE +      ++HPDSP TG  WM + +SF K+KL+N  +D    IILNSMHKY P+L++V+A   N   +    +    F+ET FI+VT+YQN +IT+LKI  NPFAKGFR  E+  L+  R Q
Sbjct:   55 VVLHERELWRRFHEAGTEMIITKAGRRMFPSYKVKVSGMNPKTKYILLVDIVPADDHRYKFCDNKWMVAGKAEPAMPGRL-YVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAYCTHVFHETSFISVTSYQNHKITQLKIENNPFAKGFRGSEDGDLRVSRIQ 249          
BLAST of T box transcription factor tbx2 vs. Ensembl Medaka
Match: tbx16 (T-box-containing protein TBX6L [Source:NCBI gene;Acc:101163256])

HSP 1 Score: 191.43 bits (485), Expect = 2.633e-56
Identity = 95/191 (49.74%), Postives = 130/191 (68.06%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERS 810
            + LED  LW  F    TEM+ITK GRRMFP  KV + GL P AKY+LL+D+V  +  RYK+  ++W  +GKAE      + ++HPDSP  G  WM +SISF K+KL+N  +D+   IIL+SMH+Y P+ ++V+A +L    +  +  F+F ET F AVTAYQN +ITKLKI++NPFAKGFR+  + KK R+
Sbjct:   33 MTLEDPNLWRTFHEIGTEMIITKPGRRMFPHCKVSLSGLIPCAKYILLVDMVPEDGFRYKWNKDKWEVAGKAEPQPPCRT-YVHPDSPAPGSHWMKQSISFLKLKLTNNTLDQHGHIILHSMHRYHPRFHVVQADDLFSVRWSVFQMFTFPETSFTAVTAYQNTKITKLKIDHNPFAKGFRDEGTNKKRRA 222          
BLAST of T box transcription factor tbx2 vs. Ensembl Medaka
Match: tbx5a (T-box transcription factor TBX5-A [Source:NCBI gene;Acc:101161908])

HSP 1 Score: 192.2 bits (487), Expect = 6.117e-56
Identity = 95/195 (48.72%), Postives = 133/195 (68.21%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSP---FIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRA--QNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            V L ++ELW +F    TEM+ITK GRRMFPSFKV++ GL+P  KY+LL+D+V ++++RYK+  N+W  +GKAE +     P   ++HPDSP TG  WM + +SF K+KL+N  +D    IILNSMHKY P++++V+A   N   +    +    F ET FIAVT+YQN +IT+LKI  NPFAKGFR +  ++  R
Sbjct:   55 VYLHERELWMKFHEVGTEMIITKAGRRMFPSFKVKVTGLNPKTKYILLMDVVPADDHRYKFADNKWSVTGKAEPAM----PGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRIHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHR 245          
BLAST of T box transcription factor tbx2 vs. Planmine SMEST
Match: SMESG000023378.1 (SMESG000023378.1)

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 332/332 (100.00%), Postives = 332/332 (100.00%), Query Frame = 1
Query:   61 MFLKGSHRSLRFHPYDLPYERMPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC 1056
            MFLKGSHRSLRFHPYDLPYERMPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC
Sbjct:    1 MFLKGSHRSLRFHPYDLPYERMPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC 332          
BLAST of T box transcription factor tbx2 vs. Planmine SMEST
Match: SMESG000023378.1 (SMESG000023378.1)

HSP 1 Score: 646.736 bits (1667), Expect = 0.000e+0
Identity = 311/311 (100.00%), Postives = 311/311 (100.00%), Query Frame = 1
Query:  124 MPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC 1056
            MPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC
Sbjct:    1 MPLFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEYQPAIFNKSDMTSIEKRETPDQNKKPKQGFLIC 311          
BLAST of T box transcription factor tbx2 vs. Planmine SMEST
Match: SMESG000061015.1 (SMESG000061015.1)

HSP 1 Score: 230.72 bits (587), Expect = 9.137e-70
Identity = 116/228 (50.88%), Postives = 162/228 (71.05%), Query Frame = 1
Query:  130 LFSRPWLKQNSFDDISTNVLAAQQYDWRVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKA--EISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKER 807
            L + P+L  + F+  S NV   Q  D  ++  D P VEL D++LW +F    TEMVITK+GRRMFP +KV++ GLD  AKY++L+D+V  ++ RYK+++NQW+ +GKA  E+ + +   +IHPDSPTTGE+WM K ISFHK+KL+N   DK    ILNSMHKY P+ +LVRA +++   Y  +  + F ETQFI VTAYQN++IT+LKI++NPFAKGFR+    K+E+
Sbjct:   58 LANYPFLPPDIFNPASRNV-TEQINDQDIK--DDPKVELIDRDLWEQFHAYGTEMVITKSGRRMFPPYKVQVSGLDKRAKYIMLMDVVAVDDCRYKFHNNQWMVAGKADPEMPKRM---YIHPDSPTTGEQWMQKIISFHKLKLTNNISDKHGFTILNSMHKYQPRFHLVRANDIMRLPYSTFRSYVFKETQFIGVTAYQNEKITQLKIDHNPFAKGFRDTGGGKREK 279          
BLAST of T box transcription factor tbx2 vs. Planmine SMEST
Match: SMESG000080056.1 (SMESG000080056.1)

HSP 1 Score: 201.445 bits (511), Expect = 9.068e-59
Identity = 102/220 (46.36%), Postives = 151/220 (68.64%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKD-DVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDE-FSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQ---PQNISQTKPSPNQVPSDYAVMKN 882
             +L + +LW  F N TTEMVITK+GRRMFP+FKV++ GLDP +KYVL L+++  ++NR+K+++ +W  +GKA+   +    + H +SP +GE WM K++ F+K+KL+N   DKD   ++LNSMHKY+ +L+L R  +     +C + E F F  T+FIAVTAYQND+IT+LKI++NPFAKGFR+N S ++E+ +    Q IS T P   +   D  +  N
Sbjct:  143 AKLCEDDLWKRFNNLTTEMVITKSGRRMFPAFKVQLSGLDPKSKYVLALEVMPCDDNRFKFHNGKWTLAGKADPESN-RLVYFHCESPASGESWMQKAVWFNKVKLTNNPTDKDPQHLVLNSMHKYVMRLHLFRTDDTSKIRFCLYPEVFLFKTTEFIAVTAYQNDKITQLKIDHNPFAKGFRDNGSGRREKKRMKLQQTISSTSPDSPEDSEDECLTSN 361          
BLAST of T box transcription factor tbx2 vs. Planmine SMEST
Match: SMESG000080056.1 (SMESG000080056.1)

HSP 1 Score: 201.445 bits (511), Expect = 9.283e-59
Identity = 102/220 (46.36%), Postives = 151/220 (68.64%), Query Frame = 1
Query:  238 VELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDPTAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTGEEWMSKSISFHKIKLSNTRVDKD-DVIILNSMHKYIPKLYLVRAQNLLYTNYCHWDE-FSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERSQ---PQNISQTKPSPNQVPSDYAVMKN 882
             +L + +LW  F N TTEMVITK+GRRMFP+FKV++ GLDP +KYVL L+++  ++NR+K+++ +W  +GKA+   +    + H +SP +GE WM K++ F+K+KL+N   DKD   ++LNSMHKY+ +L+L R  +     +C + E F F  T+FIAVTAYQND+IT+LKI++NPFAKGFR+N S ++E+ +    Q IS T P   +   D  +  N
Sbjct:  136 AKLCEDDLWKRFNNLTTEMVITKSGRRMFPAFKVQLSGLDPKSKYVLALEVMPCDDNRFKFHNGKWTLAGKADPESN-RLVYFHCESPASGESWMQKAVWFNKVKLTNNPTDKDPQHLVLNSMHKYVMRLHLFRTDDTSKIRFCLYPEVFLFKTTEFIAVTAYQNDKITQLKIDHNPFAKGFRDNGSGRREKKRMKLQQTISSTSPDSPEDSEDECLTSN 354          
The following BLAST results are available for this feature:
BLAST of T box transcription factor tbx2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TBX22.047e-6954.59T-box transcription factor 2 [Source:HGNC Symbol;A... [more]
TBX35.637e-6854.69T-box transcription factor 3 [Source:HGNC Symbol;A... [more]
TBX32.714e-6349.53T-box transcription factor 3 [Source:HGNC Symbol;A... [more]
TBX61.698e-6249.75T-box transcription factor 6 [Source:HGNC Symbol;A... [more]
TBX61.698e-6249.75T-box transcription factor 6 [Source:HGNC Symbol;A... [more]
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BLAST of T box transcription factor tbx2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tbx-22.165e-6451.26T-box protein 2 [Source:UniProtKB/Swiss-Prot;Acc:... [more]
tbx-22.165e-6451.26T-box protein 2 [Source:UniProtKB/Swiss-Prot;Acc:... [more]
tbx-78.055e-5638.89Putative T-box protein 7 [Source:UniProtKB/Swiss-... [more]
tbx-78.055e-5638.89Putative T-box protein 7 [Source:UniProtKB/Swiss-... [more]
tbx-71.051e-5543.87Putative T-box protein 7 [Source:UniProtKB/Swiss-... [more]
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BLAST of T box transcription factor tbx2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bi2.030e-6654.31gene:FBgn0000179 transcript:FBtr0308915[more]
bi2.306e-6654.31gene:FBgn0000179 transcript:FBtr0343569[more]
bi1.147e-6553.47gene:FBgn0000179 transcript:FBtr0300608[more]
bi1.147e-6553.47gene:FBgn0000179 transcript:FBtr0070672[more]
bi1.147e-6553.47gene:FBgn0000179 transcript:FBtr0300609[more]
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BLAST of T box transcription factor tbx2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tbx3b9.181e-6954.59T-box transcription factor 3b [Source:ZFIN;Acc:ZDB... [more]
tbx2a2.373e-6854.59T-box transcription factor 2a [Source:ZFIN;Acc:ZDB... [more]
tbx2a2.383e-6854.59T-box transcription factor 2a [Source:ZFIN;Acc:ZDB... [more]
tbx3a1.731e-6755.21T-box transcription factor 3a [Source:ZFIN;Acc:ZDB... [more]
tbx2b3.615e-6746.61T-box transcription factor 2b [Source:NCBI gene;Ac... [more]
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BLAST of T box transcription factor tbx2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tbx33.766e-6852.22T-box 3 [Source:NCBI gene;Acc:613116][more]
tbx26.821e-6854.69T-box 2 [Source:NCBI gene;Acc:619588][more]
vegt2.493e-5851.35vegt protein [Source:NCBI gene;Acc:394452][more]
vegt2.605e-5851.35vegt protein [Source:NCBI gene;Acc:394452][more]
vegt3.139e-5851.35vegt protein [Source:NCBI gene;Acc:394452][more]
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BLAST of T box transcription factor tbx2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tbx32.947e-6954.59T-box 3 [Source:MGI Symbol;Acc:MGI:98495][more]
Tbx32.947e-6954.59T-box 3 [Source:MGI Symbol;Acc:MGI:98495][more]
Tbx23.675e-6954.59T-box 2 [Source:MGI Symbol;Acc:MGI:98494][more]
Tbx31.585e-6449.54T-box 3 [Source:MGI Symbol;Acc:MGI:98495][more]
Tbx62.763e-6149.75T-box 6 [Source:MGI Symbol;Acc:MGI:102539][more]
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BLAST of T box transcription factor tbx2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6PCL0|TBX2B_XENLA3.419e-6948.10T-box transcription factor TBX2-B OS=Xenopus laevi... [more]
sp|O73718|TBX3_CHICK5.157e-6955.21T-box transcription factor TBX3 (Fragment) OS=Gall... [more]
sp|Q13207|TBX2_HUMAN9.832e-6954.59T-box transcription factor TBX2 OS=Homo sapiens OX... [more]
sp|Q863A2|TBX2_CANLF1.288e-6854.59T-box transcription factor TBX2 OS=Canis lupus fam... [more]
sp|Q60707|TBX2_MOUSE2.570e-6854.59T-box transcription factor TBX2 OS=Mus musculus OX... [more]
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BLAST of T box transcription factor tbx2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5P8I4J10.000e+0100.00T-box 2/3b protein OS=Schmidtea mediterranea OX=79... [more]
F1CDE94.200e-11297.58TBX2/3b (Fragment) OS=Schmidtea polychroa OX=50054... [more]
A0A087W2314.177e-7353.70T box transcription factor tbx2 OS=Echinococcus mu... [more]
A0A068WJM54.260e-7353.70T box transcription factor tbx2 OS=Echinococcus gr... [more]
A0A0R3WBU14.537e-7351.77Uncharacterized protein OS=Taenia asiatica OX=6051... [more]
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BLAST of T box transcription factor tbx2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tbx2b1.785e-6754.69T-box transcription factor 2 [Source:NCBI gene;Acc... [more]
tbx3a7.799e-6755.21T-box transcription factor 3 [Source:NCBI gene;Acc... [more]
tbx5b8.997e-6048.80T-box transcription factor TBX5-like [Source:NCBI ... [more]
tbx5b1.216e-5850.00T-box transcription factor TBX5-like [Source:NCBI ... [more]
tbx62.973e-5848.53T-box transcription factor 6 [Source:NCBI gene;Acc... [more]
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BLAST of T box transcription factor tbx2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000004087.18.983e-4847.98pep scaffold:Pmarinus_7.0:GL483204:5206:18999:-1 g... [more]
TBR13.059e-4739.11T-box brain transcription factor 1 [Source:HGNC Sy... [more]
ENSPMAT00000008915.18.355e-4042.47pep scaffold:Pmarinus_7.0:GL481372:6049:9031:1 gen... [more]
ENSPMAT00000007664.11.878e-3739.01pep scaffold:Pmarinus_7.0:GL477495:60408:67857:-1 ... [more]
ENSPMAT00000004398.13.129e-2047.37pep scaffold:Pmarinus_7.0:GL481394:165233:166024:1... [more]
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BLAST of T box transcription factor tbx2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of T box transcription factor tbx2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO418881.609e-6453.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO418891.666e-6050.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO350742.801e-5849.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO350861.177e-5548.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO466647.857e-5545.69Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of T box transcription factor tbx2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TBX27.301e-6954.08T-box transcription factor 2 [Source:NCBI gene;Acc... [more]
tbx3a5.758e-6654.31T-box transcription factor 3 [Source:NCBI gene;Acc... [more]
tbx43.190e-5748.98T-box transcription factor 4 [Source:NCBI gene;Acc... [more]
tbx162.633e-5649.74T-box-containing protein TBX6L [Source:NCBI gene;A... [more]
tbx5a6.117e-5648.72T-box transcription factor TBX5-A [Source:NCBI gen... [more]
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BLAST of T box transcription factor tbx2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000023378.10.000e+0100.00SMESG000023378.1[more]
SMESG000023378.10.000e+0100.00SMESG000023378.1[more]
SMESG000061015.19.137e-7050.88SMESG000061015.1[more]
SMESG000080056.19.068e-5946.36SMESG000080056.1[more]
SMESG000080056.19.283e-5946.36SMESG000080056.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30006011 ID=SMED30006011|Name=T box transcription factor tbx2|organism=Schmidtea mediterranea sexual|type=transcript|length=1113bp
CTTCAATAACTATTTCAATGTAAGCATTGTCAGTGGTGTCAAACTAAAAA
TCCATTTATTATGTTTTTAAAAGGTTCTCATCGTTCATTAAGATTTCATC
CATACGATTTGCCTTATGAAAGGATGCCCTTGTTTTCACGACCATGGTTG
AAACAGAATTCCTTTGATGACATTTCAACAAACGTTTTGGCAGCACAGCA
ATATGATTGGCGAGTTCGATCGCTTGACCATCCAGTCGTTGAACTCGAAG
ACAAAGAATTATGGACTGAATTTTTTAACAAAACCACAGAGATGGTCATT
ACAAAAACTGGAAGGCGAATGTTTCCGTCATTTAAAGTACGGATCAAGGG
ATTAGACCCTACCGCAAAATATGTGTTGCTATTAGACATTGTGCTGAGCA
ACGAAAATCGATATAAATATTACCACAATCAGTGGATCAAGTCAGGCAAA
GCCGAAATCAGTCAGCATTTACACTCCCCATTCATACACCCTGATTCTCC
GACGACCGGGGAGGAATGGATGAGTAAATCAATTTCGTTTCATAAGATCA
AACTATCAAACACTCGTGTCGACAAAGATGATGTGATAATTCTGAATTCC
ATGCACAAATATATCCCTAAATTATATCTCGTCAGAGCTCAGAATCTTCT
CTACACAAATTATTGTCATTGGGACGAATTCTCATTTTATGAAACTCAAT
TCATCGCTGTTACTGCCTACCAAAATGATCAGATAACGAAATTAAAAATA
AATTACAATCCATTTGCAAAAGGTTTCCGAGAAAATTGTAGCTTGAAAAA
AGAAAGAAGTCAACCTCAAAATATTTCACAAACAAAACCGAGTCCAAACC
AAGTGCCATCCGATTACGCAGTCATGAAAAATAAATTATTAAAGGAATTT
TCACAAAGAAAAAAGGTACTGAGCCGGCTGTGCAATTTCAGTCCGCGACC
ACAAGAATATCAGCCAGCTATTTTCAATAAATCCGACATGACATCAATTG
AAAAACGAGAGACACCAGATCAAAATAAAAAGCCAAAACAAGGATTTCTC
ATTTGTGATTTATTGGACTGATTGTCGTCGTAATTATTTACTAATTTCCT
TTATAGATTATGG
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protein sequence of SMED30006011-orf-1

>SMED30006011-orf-1 ID=SMED30006011-orf-1|Name=SMED30006011-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=337bp
MFLKGSHRSLRFHPYDLPYERMPLFSRPWLKQNSFDDISTNVLAAQQYDW
RVRSLDHPVVELEDKELWTEFFNKTTEMVITKTGRRMFPSFKVRIKGLDP
TAKYVLLLDIVLSNENRYKYYHNQWIKSGKAEISQHLHSPFIHPDSPTTG
EEWMSKSISFHKIKLSNTRVDKDDVIILNSMHKYIPKLYLVRAQNLLYTN
YCHWDEFSFYETQFIAVTAYQNDQITKLKINYNPFAKGFRENCSLKKERS
QPQNISQTKPSPNQVPSDYAVMKNKLLKEFSQRKKVLSRLCNFSPRPQEY
QPAIFNKSDMTSIEKRETPDQNKKPKQGFLICDLLD*
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Aliases
The feature 'T box transcription factor tbx2' has the following synonyms
Synonym
Spol-TBX2/3b
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000028Category 2 cell
PLANA:0000099neuron
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR036960T-box_sf
IPR001699TF_T-box
IPR018186TF_T-box_CS
IPR008967p53-like_TF_DNA-bd
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0006351transcription, DNA-templated
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
Vocabulary: molecular function
TermDefinition
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0003677DNA binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001699Transcription factor, T-boxPRINTSPR00937TBOXcoord: 158..167
score: 61.52
coord: 233..241
score: 82.61
coord: 177..191
score: 58.84
coord: 141..154
score: 61.02
coord: 212..225
score: 76.24
coord: 75..99
score: 63.3
IPR001699Transcription factor, T-boxSMARTSM00425tbox5coord: 57..246
e-value: 8.0E-88
score: 307.8
IPR001699Transcription factor, T-boxPFAMPF00907T-boxcoord: 60..241
e-value: 2.2E-71
score: 239.9
IPR001699Transcription factor, T-boxPANTHERPTHR11267T-BOX PROTEIN-RELATEDcoord: 54..303
IPR001699Transcription factor, T-boxPROSITEPS50252TBOX_3coord: 62..241
score: 66.386
IPR001699Transcription factor, T-boxCDDcd00182TBOXcoord: 60..242
e-value: 3.33066E-96
score: 281.013
IPR036960T-box superfamilyGENE3DG3DSA:2.60.40.820coord: 55..247
e-value: 2.5E-77
score: 261.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 304..327
NoneNo IPR availablePANTHERPTHR11267:SF107OPTOMOTOR-BLIND PROTEINcoord: 54..303
IPR018186Transcription factor, T-box, conserved sitePROSITEPS01283TBOX_1coord: 67..86
IPR018186Transcription factor, T-box, conserved sitePROSITEPS01264TBOX_2coord: 142..160
IPR008967p53-like transcription factor, DNA-bindingSUPERFAMILYSSF49417p53-like transcription factorscoord: 60..241