Ras-responsive element-binding protein 1

Overview
NameRas-responsive element-binding protein 1
Smed IDSMED30005992
Length (bp)1506
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ras-responsive element-binding protein 1 (SMED30005992) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-responsive element-binding protein 1 (SMED30005992) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-responsive element-binding protein 1 (SMED30005992) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-responsive element-binding protein 1 (SMED30005992) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005992

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30005992SMESG000027936.1 dd_Smed_v4_13753_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30005992SMESG000027936.1 dd_Smed_v4_13753_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30005992SMESG000027936.1 dd_Smed_v4_13753_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005992SMESG000027936.1 Contig4751newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005992SMESG000027936.1 Contig4751uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005992SMESG000032467.1 Contig4751newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005992SMESG000032467.1 Contig4751uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Human
Match: RREB1 (ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449])

HSP 1 Score: 78.1814 bits (191), Expect = 1.765e-14
Identity = 35/56 (62.50%), Postives = 38/56 (67.86%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            ITCP   C + FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH  R HGV
Sbjct: 1246 ITCPH--CPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1299
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Human
Match: RREB1 (ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449])

HSP 1 Score: 77.7962 bits (190), Expect = 2.723e-14
Identity = 35/56 (62.50%), Postives = 38/56 (67.86%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            ITCP   C + FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH  R HGV
Sbjct: 1246 ITCPH--CPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1299
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Human
Match: KLF7 (Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC:6350])

HSP 1 Score: 53.9138 bits (128), Expect = 1.857e-8
Identity = 22/50 (44.00%), Postives = 26/50 (52.00%), Query Frame = 1 
Query:  949 CPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTR 1098
            C  EGC  +F  +  L RH   HT  KPFKC  C +CFS   +   HM R
Sbjct:   61 CSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKR 110
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Human
Match: GTF3A (general transcription factor IIIA [Source:HGNC Symbol;Acc:HGNC:4662])

HSP 1 Score: 53.1434 bits (126), Expect = 6.356e-8
Identity = 26/56 (46.43%), Postives = 32/56 (57.14%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTR--CTKCFSTKSNRERHMTRVH 1104
              C  EGC + F  +  L RHILTHT  KPF C    C + F+TKSN ++H  R H
Sbjct:   70 FVCDYEGCGKAFIRDYHLSRHILTHTGEKPFVCAANGCDQKFNTKSNLKKHFERKH 125
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Human
Match: MECOM (MDS1 and EVI1 complex locus [Source:HGNC Symbol;Acc:HGNC:3498])

HSP 1 Score: 56.225 bits (134), Expect = 1.129e-7
Identity = 27/84 (32.14%), Postives = 43/84 (51.19%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL 1215
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGN+
Sbjct:  917 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNM 996
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Celegans
Match: egl-43 (pep chromosome:WBcel235:II:9960333:9962344:1 gene:WBGene00001207.1 transcript:R53.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:egl-43)

HSP 1 Score: 51.9878 bits (123), Expect = 4.900e-7
Identity = 20/47 (42.55%), Postives = 31/47 (65.96%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C + FP +++L RH+ THT  +P+KC  C + FS  SN +RH+  +H
Sbjct:  228 CQKVFPRSANLTRHLRTHTGEQPYKCQYCERSFSISSNLQRHVRNIH 274
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Celegans
Match: egl-43 (pep chromosome:WBcel235:II:9955185:9962344:1 gene:WBGene00001207.1 transcript:R53.3a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:egl-43)

HSP 1 Score: 52.373 bits (124), Expect = 5.375e-7
Identity = 20/47 (42.55%), Postives = 31/47 (65.96%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C + FP +++L RH+ THT  +P+KC  C + FS  SN +RH+  +H
Sbjct:  449 CQKVFPRSANLTRHLRTHTGEQPYKCQYCERSFSISSNLQRHVRNIH 495
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Celegans
Match: ztf-2 (Zinc finger putative Transcription Factor family [Source:UniProtKB/TrEMBL;Acc:Q19418])

HSP 1 Score: 51.6026 bits (122), Expect = 6.678e-7
Identity = 22/65 (33.85%), Postives = 37/65 (56.92%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKAT 1158
            C  +  W S ++RH   HT+ +PFKC  C++    K++  RH+ + HG+R+  SK+   +   AT
Sbjct:   92 CGYQGKWVSEMIRHKRVHTSERPFKCRYCSRTSKWKADLIRHVAKTHGIRVV-SKYSRSKVFDAT 155
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Celegans
Match: egrh-1 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:Q18250])

HSP 1 Score: 50.0618 bits (118), Expect = 3.084e-6
Identity = 21/52 (40.38%), Postives = 29/52 (55.77%), Query Frame = 1 
Query:  949 CPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            CP +GC ++F  +  L RHI  HT  KPF+C  C + FS   +   H+ R H
Sbjct:  376 CPRDGCDRRFSRSDELTRHIRIHTGQKPFQCRICMRAFSRSDHLTTHV-RTH 426
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Celegans
Match: klf-1 (Kruppel-Like Factor (Zinc finger protein) [Source:UniProtKB/TrEMBL;Acc:Q9TZ64])

HSP 1 Score: 49.6766 bits (117), Expect = 3.880e-6
Identity = 20/54 (37.04%), Postives = 29/54 (53.70%), Query Frame = 1 
Query:  937 KLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTR 1098
            K   C  +GC  +F  +  L RH   HT  +PFKC++C++ FS   +   HM R
Sbjct:  442 KPYECSWDGCDWRFARSDELTRHYRKHTGDRPFKCSQCSRAFSRSDHLSLHMKR 495
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Fly
Match: peb (gene:FBgn0003053 transcript:FBtr0100265)

HSP 1 Score: 80.1073 bits (196), Expect = 2.364e-15
Identity = 34/59 (57.63%), Postives = 42/59 (71.19%), Query Frame = 1 
Query:  931 APKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHG 1107
            AP  ++CP   C + FPW+SSL RHILTHT  KPFKC+ C   F+TKSN +RH+ R HG
Sbjct: 1447 APNRVSCPY--CQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHG 1503
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Fly
Match: peb (gene:FBgn0003053 transcript:FBtr0070680)

HSP 1 Score: 80.1073 bits (196), Expect = 2.364e-15
Identity = 34/59 (57.63%), Postives = 42/59 (71.19%), Query Frame = 1 
Query:  931 APKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHG 1107
            AP  ++CP   C + FPW+SSL RHILTHT  KPFKC+ C   F+TKSN +RH+ R HG
Sbjct: 1447 APNRVSCPY--CQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHG 1503
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Fly
Match: CG10348 (gene:FBgn0032707 transcript:FBtr0343112)

HSP 1 Score: 53.9138 bits (128), Expect = 2.704e-7
Identity = 20/47 (42.55%), Postives = 31/47 (65.96%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C + FP +++L RH+ THT  +P+KC  C + FS  SN +RH+  +H
Sbjct:  316 CGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIH 362
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Fly
Match: CG10348 (gene:FBgn0032707 transcript:FBtr0301647)

HSP 1 Score: 53.9138 bits (128), Expect = 2.704e-7
Identity = 20/47 (42.55%), Postives = 31/47 (65.96%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C + FP +++L RH+ THT  +P+KC  C + FS  SN +RH+  +H
Sbjct:  316 CGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIH 362
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Fly
Match: ham (gene:FBgn0045852 transcript:FBtr0332016)

HSP 1 Score: 53.1434 bits (126), Expect = 4.414e-7
Identity = 19/47 (40.43%), Postives = 30/47 (63.83%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C + FP +++L RH+ THT  +P+ C  C + FS  SN +RH+  +H
Sbjct:  465 CGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIH 511
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Zebrafish
Match: rreb1b (ras responsive element binding protein 1b [Source:ZFIN;Acc:ZDB-GENE-070912-273])

HSP 1 Score: 77.0258 bits (188), Expect = 3.005e-14
Identity = 33/56 (58.93%), Postives = 39/56 (69.64%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            +TCP   C + FPW SSL RH+LTHT  KP+ C +C   FSTKSN ERH+ R HGV
Sbjct: 1193 MTCPY--CPRLFPWASSLQRHMLTHTGQKPYPCPQCDSFFSTKSNCERHLLRKHGV 1246
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Zebrafish
Match: rreb1b (ras responsive element binding protein 1b [Source:ZFIN;Acc:ZDB-GENE-070912-273])

HSP 1 Score: 76.2554 bits (186), Expect = 4.494e-14
Identity = 33/56 (58.93%), Postives = 39/56 (69.64%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            +TCP   C + FPW SSL RH+LTHT  KP+ C +C   FSTKSN ERH+ R HGV
Sbjct: 1073 MTCPY--CPRLFPWASSLQRHMLTHTGQKPYPCPQCDSFFSTKSNCERHLLRKHGV 1126
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Zebrafish
Match: rreb1a (ras responsive element binding protein 1a [Source:ZFIN;Acc:ZDB-GENE-030219-137])

HSP 1 Score: 74.3294 bits (181), Expect = 2.059e-13
Identity = 31/56 (55.36%), Postives = 38/56 (67.86%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            + CP   C + FPW SSL RH+LTHT  KP+ C +C   FSTKSN ERH+ R HG+
Sbjct: 1202 MICPF--CPRVFPWASSLQRHMLTHTGQKPYPCPQCDAFFSTKSNCERHLLRKHGI 1255

HSP 2 Score: 49.6766 bits (117), Expect = 8.816e-6
Identity = 20/47 (42.55%), Postives = 29/47 (61.70%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C +     SSL RH+L H+  +P+KCT C + F+T  N  RHM ++H
Sbjct:  175 CGKSLSSASSLDRHMLVHSGERPYKCTVCHQTFTTNGNMHRHM-KIH 220
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Zebrafish
Match: rreb1a (ras responsive element binding protein 1a [Source:ZFIN;Acc:ZDB-GENE-030219-137])

HSP 1 Score: 74.3294 bits (181), Expect = 2.064e-13
Identity = 31/56 (55.36%), Postives = 38/56 (67.86%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            + CP   C + FPW SSL RH+LTHT  KP+ C +C   FSTKSN ERH+ R HG+
Sbjct: 1224 MICPF--CPRVFPWASSLQRHMLTHTGQKPYPCPQCDAFFSTKSNCERHLLRKHGI 1277

HSP 2 Score: 49.6766 bits (117), Expect = 8.532e-6
Identity = 20/47 (42.55%), Postives = 29/47 (61.70%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C +     SSL RH+L H+  +P+KCT C + F+T  N  RHM ++H
Sbjct:  197 CGKSLSSASSLDRHMLVHSGERPYKCTVCHQTFTTNGNMHRHM-KIH 242
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Zebrafish
Match: rreb1a (ras responsive element binding protein 1a [Source:ZFIN;Acc:ZDB-GENE-030219-137])

HSP 1 Score: 74.3294 bits (181), Expect = 2.110e-13
Identity = 31/56 (55.36%), Postives = 38/56 (67.86%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            + CP   C + FPW SSL RH+LTHT  KP+ C +C   FSTKSN ERH+ R HG+
Sbjct: 1188 MICPF--CPRVFPWASSLQRHMLTHTGQKPYPCPQCDAFFSTKSNCERHLLRKHGI 1241

HSP 2 Score: 49.6766 bits (117), Expect = 8.584e-6
Identity = 20/47 (42.55%), Postives = 29/47 (61.70%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C +     SSL RH+L H+  +P+KCT C + F+T  N  RHM ++H
Sbjct:  161 CGKSLSSASSLDRHMLVHSGERPYKCTVCHQTFTTNGNMHRHM-KIH 206
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Xenopus
Match: RREB1 (ras responsive element binding protein 1 [Source:NCBI gene;Acc:100038225])

HSP 1 Score: 80.1073 bits (196), Expect = 3.966e-15
Identity = 35/56 (62.50%), Postives = 39/56 (69.64%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            ITCP   C + FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH+ R HGV
Sbjct: 1269 ITCPY--CPRVFPWASSLQRHMLTHTGQKPFPCAKCDAFFSTKSNCERHLLRKHGV 1322
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Xenopus
Match: RREB1 (ras responsive element binding protein 1 [Source:NCBI gene;Acc:100038225])

HSP 1 Score: 80.1073 bits (196), Expect = 4.295e-15
Identity = 35/56 (62.50%), Postives = 39/56 (69.64%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            ITCP   C + FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH+ R HGV
Sbjct: 1277 ITCPY--CPRVFPWASSLQRHMLTHTGQKPFPCAKCDAFFSTKSNCERHLLRKHGV 1330
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Xenopus
Match: RREB1 (ras responsive element binding protein 1 [Source:NCBI gene;Acc:100038225])

HSP 1 Score: 80.1073 bits (196), Expect = 4.427e-15
Identity = 35/56 (62.50%), Postives = 39/56 (69.64%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            ITCP   C + FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH+ R HGV
Sbjct: 1173 ITCPY--CPRVFPWASSLQRHMLTHTGQKPFPCAKCDAFFSTKSNCERHLLRKHGV 1226
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Xenopus
Match: RREB1 (ras responsive element binding protein 1 [Source:NCBI gene;Acc:100038225])

HSP 1 Score: 80.1073 bits (196), Expect = 4.627e-15
Identity = 35/56 (62.50%), Postives = 39/56 (69.64%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            ITCP   C + FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH+ R HGV
Sbjct: 1173 ITCPY--CPRVFPWASSLQRHMLTHTGQKPFPCAKCDAFFSTKSNCERHLLRKHGV 1226
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Xenopus
Match: RREB1 (ras responsive element binding protein 1 [Source:NCBI gene;Acc:100038225])

HSP 1 Score: 80.1073 bits (196), Expect = 4.694e-15
Identity = 35/56 (62.50%), Postives = 39/56 (69.64%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            ITCP   C + FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH+ R HGV
Sbjct: 1173 ITCPY--CPRVFPWASSLQRHMLTHTGQKPFPCAKCDAFFSTKSNCERHLLRKHGV 1226
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Mouse
Match: Rreb1 (ras responsive element binding protein 1 [Source:MGI Symbol;Acc:MGI:2443664])

HSP 1 Score: 75.8702 bits (185), Expect = 6.803e-14
Identity = 34/56 (60.71%), Postives = 37/56 (66.07%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            I CP   C + FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH  R HGV
Sbjct: 1251 INCPH--CPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1304
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Mouse
Match: Rreb1 (ras responsive element binding protein 1 [Source:MGI Symbol;Acc:MGI:2443664])

HSP 1 Score: 75.8702 bits (185), Expect = 6.803e-14
Identity = 34/56 (60.71%), Postives = 37/56 (66.07%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            I CP   C + FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH  R HGV
Sbjct: 1251 INCPH--CPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1304
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Mouse
Match: Mecom (MDS1 and EVI1 complex locus [Source:MGI Symbol;Acc:MGI:95457])

HSP 1 Score: 55.8398 bits (133), Expect = 1.010e-7
Identity = 27/84 (32.14%), Postives = 43/84 (51.19%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL 1215
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGN+
Sbjct:  738 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNM 817
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Mouse
Match: Mecom (MDS1 and EVI1 complex locus [Source:MGI Symbol;Acc:MGI:95457])

HSP 1 Score: 55.8398 bits (133), Expect = 1.026e-7
Identity = 27/84 (32.14%), Postives = 43/84 (51.19%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL 1215
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGN+
Sbjct:  530 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNM 609
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Mouse
Match: Mecom (MDS1 and EVI1 complex locus [Source:MGI Symbol;Acc:MGI:95457])

HSP 1 Score: 55.8398 bits (133), Expect = 1.110e-7
Identity = 27/84 (32.14%), Postives = 43/84 (51.19%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL 1215
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGN+
Sbjct:  729 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNM 808
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. UniProt/SwissProt
Match: sp|B7ZRU9|EVI1A_XENLA (MDS1 and EVI1 complex locus protein EVI1-A OS=Xenopus laevis OX=8355 GN=mecom-a PE=1 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 4.485e-7
Identity = 28/84 (33.33%), Postives = 43/84 (51.19%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL 1215
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGNL
Sbjct:  739 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNL 818
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. UniProt/SwissProt
Match: sp|Q03112|MECOM_HUMAN (Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3)

HSP 1 Score: 56.225 bits (134), Expect = 5.423e-7
Identity = 27/84 (32.14%), Postives = 43/84 (51.19%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL 1215
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGN+
Sbjct:  917 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNM 996
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. UniProt/SwissProt
Match: sp|B7ZRM8|EVI1B_XENLA (MDS1 and EVI1 complex locus protein EVI1-B OS=Xenopus laevis OX=8355 GN=mecom-b PE=2 SV=1)

HSP 1 Score: 56.225 bits (134), Expect = 5.653e-7
Identity = 28/84 (33.33%), Postives = 43/84 (51.19%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL 1215
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGNL
Sbjct:  736 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHIRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNL 815
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. UniProt/SwissProt
Match: sp|P14404|MECOM_MOUSE (Histone-lysine N-methyltransferase MECOM OS=Mus musculus OX=10090 GN=Mecom PE=1 SV=2)

HSP 1 Score: 56.225 bits (134), Expect = 6.389e-7
Identity = 27/84 (32.14%), Postives = 43/84 (51.19%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL 1215
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGN+
Sbjct:  919 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNM 998
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. UniProt/SwissProt
Match: sp|P26634|EGR2_CERTH (E3 SUMO-protein ligase EGR2 (Fragment) OS=Cerdocyon thous OX=9620 GN=EGR2 PE=3 SV=1)

HSP 1 Score: 48.9062 bits (115), Expect = 1.547e-6
Identity = 21/49 (42.86%), Postives = 28/49 (57.14%), Query Frame = 1 
Query:  958 EGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            EGC ++F  +  L RHI  HT HKPF+C  C + FS   +   H+ R H
Sbjct:    2 EGCDRRFSASDELTRHIRIHTGHKPFQCAICMRNFSRSDHLTTHI-RTH 49
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. TrEMBL
Match: A0A0X3NNP2 (Uncharacterized protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR160195 PE=4 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 7.917e-45
Identity = 91/158 (57.59%), Postives = 108/158 (68.35%), Query Frame = 1 
Query:  928 DAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSE----NGNLVDETIFPNDKEINIT-ELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNN 1386
            DAP+LITCP+ GC QKFPW+SSL RHILTHT HKPF CTRCTK FSTKSNRERHM RVH V + R K K+ Q        S+   +E AD      +GN     + P+  +  +T EL EEE   M+NNDR+AEDISN LL+ AG P+VEPNP RLN+
Sbjct:  549 DAPRLITCPVAGCKQKFPWHSSLKRHILTHTPHKPFACTRCTKSFSTKSNRERHMERVHRVSLKRQKQKNQQLWTGASGGSTNGAEETADGSVTENDGNSAPVLVTPSSTDDGLTDELREEEIASMNNNDRQAEDISNTLLRSAGSPIVEPNPERLNS 706
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. TrEMBL
Match: A0A430QNM5 (Ras-responsive element-binding protein 1 OS=Schistosoma bovis OX=6184 GN=DC041_0012591 PE=4 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.124e-42
Identity = 92/157 (58.60%), Postives = 109/157 (69.43%), Query Frame = 1 
Query:  928 DAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL--VDETIFP-NDKEI-NITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNN 1386
            DAPKLITCP+ GC QKFPWNSSL RHILTHT HKPF CTRCTK FSTKSNRERHM RVH V + R + +  Q+  +    SS          N NL  +  T F  ND+E+ NI EL E+E I M++N+++AEDISN+LL  AG P+VEPNP RL N
Sbjct: 1089 DAPKLITCPIAGCQQKFPWNSSLKRHILTHTPHKPFACTRCTKSFSTKSNRERHMERVHRVSLKRQRQRFHQSNMSIQSPSSGDNRSELSGHNSNLNSISRTNFGDNDQELDNIEELREDEIISMNSNEKQAEDISNSLLIRAGDPVVEPNPERLYN 1245
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. TrEMBL
Match: A0A095C1T4 (Ras-responsive element-binding protein 1 OS=Schistosoma haematobium OX=6185 GN=MS3_03806 PE=4 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.125e-42
Identity = 92/157 (58.60%), Postives = 109/157 (69.43%), Query Frame = 1 
Query:  928 DAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL--VDET-IFPNDKEI-NITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNN 1386
            DAPKLITCP+ GC QKFPWNSSL RHILTHT HKPF CTRCTK FSTKSNRERHM RVH V + R + +  Q+  +    SS          N NL  +  T I  ND+E+ NI EL E+E I M++N+++AEDISN+LL  AG P+VEPNP RL N
Sbjct: 1078 DAPKLITCPIAGCQQKFPWNSSLKRHILTHTPHKPFACTRCTKSFSTKSNRERHMERVHRVSLKRQRQRFHQSNMSIQSPSSGDNRSELSGHNSNLNSISRTNIGDNDQELDNIEELREDEIISMNSNEKQAEDISNSLLIRAGDPVVEPNPERLYN 1234
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. TrEMBL
Match: A0A5K4FBW2 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.170e-42
Identity = 92/157 (58.60%), Postives = 109/157 (69.43%), Query Frame = 1 
Query:  928 DAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL--VDET-IFPNDKEI-NITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNN 1386
            DAPKLITCP+ GC QKFPWNSSL RHILTHT HKPF CTRCTK FSTKSNRERHM RVH V + R + +  Q+  +    SS          N NL  +  T I  ND+E+ NI EL E+E I M++N+++AEDISN+LL  AG P+VEPNP RL N
Sbjct: 1011 DAPKLITCPIAGCQQKFPWNSSLKRHILTHTPHKPFACTRCTKSFSTKSNRERHMERVHRVSLKRQRQRFHQSNMSIQSPSSGDNRSELSGHNSNLNSISRTNIGDNDQELDNIEELREDEIISMNSNEKQAEDISNSLLIRAGDPVVEPNPERLYN 1167
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. TrEMBL
Match: A0A183QKD9 (Uncharacterized protein OS=Schistosoma rodhaini OX=6188 PE=4 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.337e-42
Identity = 92/157 (58.60%), Postives = 109/157 (69.43%), Query Frame = 1 
Query:  928 DAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNL--VDET-IFPNDKEI-NITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNN 1386
            DAPKLITCP+ GC QKFPWNSSL RHILTHT HKPF CTRCTK FSTKSNRERHM RVH V + R + +  Q+  +    SS          N NL  +  T I  ND+E+ NI EL E+E I M++N+++AEDISN+LL  AG P+VEPNP RL N
Sbjct: 1057 DAPKLITCPIAGCQQKFPWNSSLKRHILTHTPHKPFACTRCTKSFSTKSNRERHMERVHRVSLKRQRQRFHQSNMSIQSPSSGDNRSELSGHNSNLNSISRTNIGDNDQELDNIEELREDEIISMNSNEKQAEDISNSLLIRAGDPVVEPNPERLYN 1213
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Cavefish
Match: rreb1b (ras responsive element binding protein 1b [Source:ZFIN;Acc:ZDB-GENE-070912-273])

HSP 1 Score: 78.9518 bits (193), Expect = 5.864e-15
Identity = 41/113 (36.28%), Postives = 60/113 (53.10%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPN-DKEINITELSEEE 1278
            + CP   C ++FPW SSL RH+LTHT  KPF C +C   FSTKSN ERH+ R HG+        ++   K   +E S+   +        + D+++ P  +KE    ++  EE
Sbjct: 1168 MKCPY--CPREFPWTSSLQRHMLTHTGQKPFPCAQCDAFFSTKSNCERHLLRKHGISSRNMLQNTVSGLKPKSDEGSQGSTDCVSDAEPAVGDDSVIPGKEKEGTANDVLTEE 1278
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Cavefish
Match: klf6a (Kruppel like factor 6 [Source:NCBI gene;Acc:103031989])

HSP 1 Score: 53.5286 bits (127), Expect = 1.784e-7
Identity = 23/54 (42.59%), Postives = 28/54 (51.85%), Query Frame = 1 
Query:  937 KLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTR 1098
            K   C  EGC  +F  +  L RH   HT  KPFKC+ C +CFS   +   HM R
Sbjct:  232 KPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKR 285
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Cavefish
Match: klf6a (Kruppel like factor 6 [Source:NCBI gene;Acc:103031989])

HSP 1 Score: 53.1434 bits (126), Expect = 2.022e-7
Identity = 23/54 (42.59%), Postives = 28/54 (51.85%), Query Frame = 1 
Query:  937 KLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTR 1098
            K   C  EGC  +F  +  L RH   HT  KPFKC+ C +CFS   +   HM R
Sbjct:  215 KPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKR 268
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Cavefish
Match: klf7b (Krueppel-like factor 7 [Source:NCBI gene;Acc:103037347])

HSP 1 Score: 52.373 bits (124), Expect = 3.977e-7
Identity = 23/54 (42.59%), Postives = 27/54 (50.00%), Query Frame = 1 
Query:  937 KLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTR 1098
            K   C  EGC  +F  +  L RH   HT  KPFKC  C +CFS   +   HM R
Sbjct:  242 KPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKR 295
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Cavefish
Match: klf7a (Krueppel-like factor 7 [Source:NCBI gene;Acc:103039059])

HSP 1 Score: 52.373 bits (124), Expect = 4.182e-7
Identity = 23/54 (42.59%), Postives = 27/54 (50.00%), Query Frame = 1 
Query:  937 KLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTR 1098
            K   C  EGC  +F  +  L RH   HT  KPFKC  C +CFS   +   HM R
Sbjct:  228 KPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCAHCDRCFSRSDHLALHMKR 281
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Sea Lamprey
Match: egr2a (early growth response 2a [Source:ZFIN;Acc:ZDB-GENE-030723-6])

HSP 1 Score: 54.6842 bits (130), Expect = 1.817e-8
Identity = 23/64 (35.94%), Postives = 36/64 (56.25%), Query Frame = 1 
Query:  949 CPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFS------TKSNRERHMTRVHGVRINR 1122
            CP +GC ++F  +  L RH+  HT HKPF+C  C + FS      T+S+  +  T++H  +  R
Sbjct:  235 CPADGCERRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTRSDERKRHTKIHAKQKER 298
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007831.1 (pep scaffold:Pmarinus_7.0:GL477655:47469:47963:1 gene:ENSPMAG00000007084.1 transcript:ENSPMAT00000007831.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 49.6766 bits (117), Expect = 6.273e-8
Identity = 34/81 (41.98%), Postives = 40/81 (49.38%), Query Frame = 1 
Query:  937 KLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKL 1179
            K   CP+  C + F  +S L  H  THT  KPFKC+ C K FS  SN ++H  R H        FK     KA F ESS L
Sbjct:   30 KPFRCPL--CGKAFAKSSDLQSHQRTHTGEKPFKCSVCEKAFSQSSNLKKHQ-RTH---TGEKPFKCTVCEKA-FTESSPL 103
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Sea Lamprey
Match: klf12b (Kruppel-like factor 12b [Source:ZFIN;Acc:ZDB-GENE-071004-22])

HSP 1 Score: 47.7506 bits (112), Expect = 2.400e-7
Identity = 22/52 (42.31%), Postives = 27/52 (51.92%), Query Frame = 1 
Query:  949 CPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKS----NRERHM 1092
            C  +GC  KF  +  L RH   HT  KPFKC  C + FS       +R+RHM
Sbjct:   54 CTWDGCTWKFARSDELTRHFRKHTGVKPFKCVDCERSFSRSDHLALHRKRHM 105
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Sea Lamprey
Match: egr4 (early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-080204-90])

HSP 1 Score: 49.2914 bits (116), Expect = 7.461e-7
Identity = 23/49 (46.94%), Postives = 27/49 (55.10%), Query Frame = 1 
Query:  949 CPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMT 1095
            CP EGC ++F     L RHI  HT HKPF C  C + FS    R  H+T
Sbjct:  174 CPAEGCDRRFSRTDELTRHIRIHTGHKPFTCRICMRSFS----RSDHLT 218
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Sea Lamprey
Match: OVOL1 (ovo like transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:8525])

HSP 1 Score: 45.8246 bits (107), Expect = 2.186e-6
Identity = 19/49 (38.78%), Postives = 30/49 (61.22%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            C + F     L RH+ THT  +P+KC  C+K F+ + + E H+ ++HGV
Sbjct:   40 CGKGFNDTFDLKRHVRTHTGVRPYKCEACSKAFTQRCSLESHLKKIHGV 88
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Yeast
Match: USV1 (Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis; USV1 has a paralog, RGM1, that arose from the whole genome duplication [Source:SGD;Acc:S000006151])

HSP 1 Score: 48.1358 bits (113), Expect = 1.845e-6
Identity = 21/51 (41.18%), Postives = 25/51 (49.02%), Query Frame = 1 
Query:  955 MEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHG 1107
             +GC   F     L RHI  HT  KPF+C  C K FS   N ++H   VH 
Sbjct:   46 YDGCTMSFTRAEHLARHIRKHTGEKPFQCPACLKFFSRVDNLKQHRESVHA 96
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Yeast
Match: ZAP1 (Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592])

HSP 1 Score: 48.1358 bits (113), Expect = 2.521e-6
Identity = 20/52 (38.46%), Postives = 30/52 (57.69%), Query Frame = 1 
Query:  949 CPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C    C + FP    L+RH+  H+ +KP+KC  C +CFS++    +H TR H
Sbjct:  740 CLWHDCHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQH-TRTH 790
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Yeast
Match: TDA9 (Transcription factor that regulates acetate production; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; TDA9 has a paralog, RSF2, that arose from the whole genome duplication [Source:SGD;Acc:S000004546])

HSP 1 Score: 47.7506 bits (112), Expect = 3.949e-6
Identity = 31/103 (30.10%), Postives = 47/103 (45.63%), Query Frame = 1 
Query:  928 DAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFP 1236
            D P+   C +  C + F     L RH   HT  KPF C  C +CF+ +    RH  ++H   +++   +SI +   T  E   + D+N     GN   +TI P
Sbjct:   56 DKPRPFLCHI--CTRGFVRQEHLKRHQRAHTNEKPFLCVFCGRCFARRDLVLRHQHKLHSALVSK---ESINSKDKT--EIDAINDKNIIQIQGN--KQTILP 149
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Yeast
Match: ADR1 (Carbon source-responsive zinc-finger transcription factor; required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization [Source:SGD;Acc:S000002624])

HSP 1 Score: 47.3654 bits (111), Expect = 5.197e-6
Identity = 30/106 (28.30%), Postives = 48/106 (45.28%), Query Frame = 1 
Query:  931 APKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH----GVRINRSKFKSIQAAKATFEESSKLIDEN---ADSENGNLVDET 1227
            + KL +   E C + F     L RH  +HT  KP+ C  C +CF+ +    RH  ++H    G  I+ +K  S    KA    +S +  +       +NGN ++ T
Sbjct:   98 SGKLRSFVCEVCTRAFARQEHLKRHYRSHTNEKPYPCGLCNRCFTRRDLLIRHAQKIHSGNLGETISHTKKVSRTITKARKNSASSVKFQTPTYGTPDNGNFLNRT 203
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Nematostella
Match: EDO45199 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTE9])

HSP 1 Score: 59.6918 bits (143), Expect = 4.050e-11
Identity = 31/75 (41.33%), Postives = 39/75 (52.00%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH------GVRINRSKFKSIQAAKATFEES 1170
            C + F     L RHI THT  KPFKC RC K F+ + + E H+TRVH      G R  R K    +    TF+E+
Sbjct:   34 CGKGFNDTFDLKRHIRTHTGIKPFKCDRCDKAFTQRCSLEAHLTRVHSVVHKYGFRERRDKMFVCEDCGITFKEN 108
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Nematostella
Match: EDO40483 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S781])

HSP 1 Score: 55.8398 bits (133), Expect = 4.803e-10
Identity = 22/50 (44.00%), Postives = 27/50 (54.00%), Query Frame = 1 
Query:  949 CPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTR 1098
            C  EGC+ +F  +  L RH   HT  KPFKC  C +CFS   +   HM R
Sbjct:   39 CSWEGCSWRFARSDELTRHYRKHTGAKPFKCVHCDRCFSRSDHLSLHMKR 88
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Nematostella
Match: EDO45255 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTE8])

HSP 1 Score: 54.6842 bits (130), Expect = 2.687e-9
Identity = 31/79 (39.24%), Postives = 41/79 (51.90%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH------GVRINRSKFKSIQAAKATFEESSKLI 1182
            C + F     L RHI THT  KPFKC RC K F+ + + E H+TRVH      G R  R K    +    TF++S + +
Sbjct:   41 CGKGFNDTFDLKRHIRTHTGIKPFKCDRCDKAFTQRCSLEAHLTRVHSVVHKYGFRERRDKMFVCEDCGITFKDSPEFM 119
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Nematostella
Match: EDO29463 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3J9])

HSP 1 Score: 51.9878 bits (123), Expect = 1.538e-8
Identity = 23/54 (42.59%), Postives = 29/54 (53.70%), Query Frame = 1 
Query:  937 KLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTR 1098
            K   CP   C + F  +SSL +H LTHT  KP+ C+ C K FS   +R  H  R
Sbjct:   52 KPFKCPFVNCRRSFTEHSSLRKHKLTHTGEKPYSCSICGKTFSQSGSRNAHQRR 105
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Nematostella
Match: EDO26221 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TCK1])

HSP 1 Score: 50.8322 bits (120), Expect = 1.802e-8
Identity = 22/59 (37.29%), Postives = 29/59 (49.15%), Query Frame = 1 
Query:  928 DAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            +A K   CP   C  KF  +  L RH   HT  KP+ C  C + FS   +R  HM ++H
Sbjct:    2 NADKPFYCPWRNCGWKFRRSDELKRHYRRHTGEKPYACPLCGRAFSRSDHRASHMRKLH 60
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Medaka
Match: rreb1a (ras responsive element binding protein 1 [Source:NCBI gene;Acc:101168995])

HSP 1 Score: 80.4925 bits (197), Expect = 1.913e-15
Identity = 35/56 (62.50%), Postives = 39/56 (69.64%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            +TCP   C + FPW SSL RH+LTHT  KPF C RC   FSTKSN ERH+ R HGV
Sbjct: 1238 MTCPF--CPRVFPWASSLQRHMLTHTGQKPFPCPRCDAFFSTKSNCERHLLRKHGV 1291
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Medaka
Match: rreb1a (ras responsive element binding protein 1 [Source:NCBI gene;Acc:101168995])

HSP 1 Score: 80.4925 bits (197), Expect = 2.031e-15
Identity = 35/56 (62.50%), Postives = 39/56 (69.64%), Query Frame = 1 
Query:  943 ITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGV 1110
            +TCP   C + FPW SSL RH+LTHT  KPF C RC   FSTKSN ERH+ R HGV
Sbjct: 1224 MTCPF--CPRVFPWASSLQRHMLTHTGQKPFPCPRCDAFFSTKSNCERHLLRKHGV 1277
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Medaka
Match: mecom (MDS1 and EVI1 complex locus [Source:NCBI gene;Acc:101169474])

HSP 1 Score: 60.077 bits (144), Expect = 4.573e-9
Identity = 39/136 (28.68%), Postives = 60/136 (44.12%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNP 1371
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGNL    +         +EL     I+ D  D    +I  N +   GQ    P+P
Sbjct:  916 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHIRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNLSGTAM-----SSPQSELDSSSAILDDKEDSYFNEI-RNFISSTGQNQASPDP 1041
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Medaka
Match: mecom (MDS1 and EVI1 complex locus [Source:NCBI gene;Acc:101169474])

HSP 1 Score: 60.077 bits (144), Expect = 4.824e-9
Identity = 39/136 (28.68%), Postives = 60/136 (44.12%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNP 1371
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGNL    +         +EL     I+ D  D    +I  N +   GQ    P+P
Sbjct:  952 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHIRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNLSGTAM-----SSPQSELDSSSAILDDKEDSYFNEI-RNFISSTGQNQASPDP 1077
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Medaka
Match: mecom (MDS1 and EVI1 complex locus [Source:NCBI gene;Acc:101169474])

HSP 1 Score: 60.077 bits (144), Expect = 4.890e-9
Identity = 39/136 (28.68%), Postives = 60/136 (44.12%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNP 1371
            C + FP +++L RH+ THT  +P++C  C + FS  SN +RH+  +H    N+ K          F + + L       ENGNL    +         +EL     I+ D  D    +I  N +   GQ    P+P
Sbjct:  952 CGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHIRNIH----NKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNLSGTAM-----SSPQSELDSSSAILDDKEDSYFNEI-RNFISSTGQNQASPDP 1077
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Planmine SMEST
Match: SMESG000027936.1 (SMESG000027936.1)

HSP 1 Score: 828.165 bits (2138), Expect = 0.000e+0
Identity = 441/445 (99.10%), Postives = 444/445 (99.78%), Query Frame = 1 
Query:  157 LLALQNCNRSNKKELKYCIFKFCNCKYRSKFKLIRHIKNSHMKHIYNVNSQSSPIIEPLNLCIKSTNIPNSFVSPPESLGTQSELRAIQLDKFELNYLNPNFQQKFSDKILDFSTNRNSQWNFEKSLLSKISPITAAIQSFQSTNQFISSSPLLTASPISLSSPFKSDWNGLNKLDFNDNNMTHLDSRSPKSDISHTQITNLSTKSCVNTTIDAIAKNAIEHLSSKSIASDFANSNPLLEDMXXXXXXXXXXXXXXXDAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNNNQIXXXXXXXXXXXXXXXXXCHSISKERFYLDSCF 1491
            +L ++NCNRSNKKELKYCIFKFCNCKYRSKFKLIRHIKNSHMKHIYNVNSQSSPIIEPLNLCIKSTNIPNSFVSPPESLGTQSELRAIQLDKFELNYLNPNFQQKFSDKILDFSTNRNSQWNFEKSLLSKISPITAAIQSFQSTNQFISSSPLLTASPISLSSPFKSDWNGLNKLDFNDNNMTHLDSRSPKSDISHTQITNLSTKSCVNTTIDAIAKNAIEHLSSKSIASDFANSNPLLEDMKSKYNTSNKKKNSYKDAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNNNQISLLEKSLSPKSEFSSKPCHSISKERFYLDSCF
Sbjct:  417 ILHVRNCNRSNKKELKYCIFKFCNCKYRSKFKLIRHIKNSHMKHIYNVNSQSSPIIEPLNLCIKSTNIPNSFVSPPESLGTQSELRAIQLDKFELNYLNPNFQQKFSDKILDFSTNRNSQWNFEKSLLSKISPITAAIQSFQSTNQFISSSPLLTASPISLSSPFKSDWNGLNKLDFNDNNMTHLDSRSPKSDISHTQITNLSTKSCVNTTIDAIAKNAIEHLSSKSIASDFANSNPLLEDMKSKYNTSNKKKNSYKDAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNNNQISLLEKSLSPKSEFSSKPCHSISKERFYLDSCF 861

HSP 2 Score: 51.9878 bits (123), Expect = 9.758e-7
Identity = 22/47 (46.81%), Postives = 30/47 (63.83%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C+++   NSSL RH+LTH+ H+PF C  C K F+T  N  RH+   H
Sbjct:  168 CSKELSSNSSLERHLLTHSNHRPFSCFMCDKKFTTNGNLSRHIKTSH 214
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Planmine SMEST
Match: SMESG000027936.1 (SMESG000027936.1)

HSP 1 Score: 827.395 bits (2136), Expect = 0.000e+0
Identity = 441/445 (99.10%), Postives = 444/445 (99.78%), Query Frame = 1 
Query:  157 LLALQNCNRSNKKELKYCIFKFCNCKYRSKFKLIRHIKNSHMKHIYNVNSQSSPIIEPLNLCIKSTNIPNSFVSPPESLGTQSELRAIQLDKFELNYLNPNFQQKFSDKILDFSTNRNSQWNFEKSLLSKISPITAAIQSFQSTNQFISSSPLLTASPISLSSPFKSDWNGLNKLDFNDNNMTHLDSRSPKSDISHTQITNLSTKSCVNTTIDAIAKNAIEHLSSKSIASDFANSNPLLEDMXXXXXXXXXXXXXXXDAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNNNQIXXXXXXXXXXXXXXXXXCHSISKERFYLDSCF 1491
            +L ++NCNRSNKKELKYCIFKFCNCKYRSKFKLIRHIKNSHMKHIYNVNSQSSPIIEPLNLCIKSTNIPNSFVSPPESLGTQSELRAIQLDKFELNYLNPNFQQKFSDKILDFSTNRNSQWNFEKSLLSKISPITAAIQSFQSTNQFISSSPLLTASPISLSSPFKSDWNGLNKLDFNDNNMTHLDSRSPKSDISHTQITNLSTKSCVNTTIDAIAKNAIEHLSSKSIASDFANSNPLLEDMKSKYNTSNKKKNSYKDAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNNNQISLLEKSLSPKSEFSSKPCHSISKERFYLDSCF
Sbjct:  402 ILHVRNCNRSNKKELKYCIFKFCNCKYRSKFKLIRHIKNSHMKHIYNVNSQSSPIIEPLNLCIKSTNIPNSFVSPPESLGTQSELRAIQLDKFELNYLNPNFQQKFSDKILDFSTNRNSQWNFEKSLLSKISPITAAIQSFQSTNQFISSSPLLTASPISLSSPFKSDWNGLNKLDFNDNNMTHLDSRSPKSDISHTQITNLSTKSCVNTTIDAIAKNAIEHLSSKSIASDFANSNPLLEDMKSKYNTSNKKKNSYKDAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVRLNNNQISLLEKSLSPKSEFSSKPCHSISKERFYLDSCF 846

HSP 2 Score: 51.9878 bits (123), Expect = 1.022e-6
Identity = 22/48 (45.83%), Postives = 30/48 (62.50%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHG 1107
            C+++   NSSL RH+LTH+ H+PF C  C K F+T  N  RH+   H 
Sbjct:  168 CSKELSSNSSLERHLLTHSNHRPFSCFMCDKKFTTNGNLSRHIKTSHN 215
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Planmine SMEST
Match: SMESG000059614.1 (SMESG000059614.1)

HSP 1 Score: 179.489 bits (454), Expect = 4.514e-50
Identity = 88/150 (58.67%), Postives = 106/150 (70.67%), Query Frame = 1 
Query:  928 DAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADSENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQPLVEPNPVR 1377
            DAPKLI CPM GC QKFPWNSSLMRHILTHTAHKPF+C RC+KCFSTKSNRERHM RVHG+++NRS+ KS  +            D N     G++ +       K  N   LSE+EWI M ++DR+AEDIS++LLK AG P++EPNP R
Sbjct:  375 DAPKLIRCPMNGCTQKFPWNSSLMRHILTHTAHKPFQCIRCSKCFSTKSNRERHMHRVHGIKVNRSRSKSSISP-----------DRNI---CGSIKETFSVEYSKSSNSEFLSEQEWIQMSSSDRKAEDISHSLLKQAGDPVIEPNPHR 510

HSP 2 Score: 55.4546 bits (132), Expect = 5.763e-8
Identity = 23/48 (47.92%), Postives = 30/48 (62.50%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVHG 1107
            C ++   NSSL RH+LTH+ H+PF C  C K F+T  N  RH+   HG
Sbjct:  106 CGKELSSNSSLERHLLTHSNHRPFDCQLCGKKFTTNGNLSRHIKASHG 153
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Planmine SMEST
Match: SMESG000028951.1 (SMESG000028951.1)

HSP 1 Score: 58.9214 bits (141), Expect = 2.838e-9
Identity = 22/47 (46.81%), Postives = 34/47 (72.34%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C + FP +++L RH+ THT  +P+KC+ CT+CFS  SN +RH+  +H
Sbjct:  249 CGKLFPRSANLTRHVRTHTGEQPYKCSFCTRCFSISSNLQRHIRNIH 295
[Close]
BLAST of Ras-responsive element-binding protein 1 vs. Planmine SMEST
Match: SMESG000059642.1 (SMESG000059642.1)

HSP 1 Score: 55.4546 bits (132), Expect = 6.258e-8
Identity = 22/47 (46.81%), Postives = 31/47 (65.96%), Query Frame = 1 
Query:  964 CAQKFPWNSSLMRHILTHTAHKPFKCTRCTKCFSTKSNRERHMTRVH 1104
            C + FP  ++L RH+ THT  +P+KC  C KCFS  SN +RH+  +H
Sbjct:  503 CLKTFPRAANLNRHLRTHTGEQPYKCAFCDKCFSISSNMQRHVRNIH 549
The following BLAST results are available for this feature:
BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RREB11.765e-1462.50ras responsive element binding protein 1 [Source:H... [more]
RREB12.723e-1462.50ras responsive element binding protein 1 [Source:H... [more]
KLF71.857e-844.00Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC... [more]
GTF3A6.356e-846.43general transcription factor IIIA [Source:HGNC Sym... [more]
MECOM1.129e-732.14MDS1 and EVI1 complex locus [Source:HGNC Symbol;Ac... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egl-434.900e-742.55pep chromosome:WBcel235:II:9960333:9962344:1 gene:... [more]
egl-435.375e-742.55pep chromosome:WBcel235:II:9955185:9962344:1 gene:... [more]
ztf-26.678e-733.85Zinc finger putative Transcription Factor family ... [more]
egrh-13.084e-640.38EGR (Early Growth factor Response factor) Homolog ... [more]
klf-13.880e-637.04Kruppel-Like Factor (Zinc finger protein) [Source... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
peb2.364e-1557.63gene:FBgn0003053 transcript:FBtr0100265[more]
peb2.364e-1557.63gene:FBgn0003053 transcript:FBtr0070680[more]
CG103482.704e-742.55gene:FBgn0032707 transcript:FBtr0343112[more]
CG103482.704e-742.55gene:FBgn0032707 transcript:FBtr0301647[more]
ham4.414e-740.43gene:FBgn0045852 transcript:FBtr0332016[more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rreb1b3.005e-1458.93ras responsive element binding protein 1b [Source:... [more]
rreb1b4.494e-1458.93ras responsive element binding protein 1b [Source:... [more]
rreb1a2.059e-1355.36ras responsive element binding protein 1a [Source:... [more]
rreb1a2.064e-1355.36ras responsive element binding protein 1a [Source:... [more]
rreb1a2.110e-1355.36ras responsive element binding protein 1a [Source:... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RREB13.966e-1562.50ras responsive element binding protein 1 [Source:N... [more]
RREB14.295e-1562.50ras responsive element binding protein 1 [Source:N... [more]
RREB14.427e-1562.50ras responsive element binding protein 1 [Source:N... [more]
RREB14.627e-1562.50ras responsive element binding protein 1 [Source:N... [more]
RREB14.694e-1562.50ras responsive element binding protein 1 [Source:N... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rreb16.803e-1460.71ras responsive element binding protein 1 [Source:M... [more]
Rreb16.803e-1460.71ras responsive element binding protein 1 [Source:M... [more]
Mecom1.010e-732.14MDS1 and EVI1 complex locus [Source:MGI Symbol;Acc... [more]
Mecom1.026e-732.14MDS1 and EVI1 complex locus [Source:MGI Symbol;Acc... [more]
Mecom1.110e-732.14MDS1 and EVI1 complex locus [Source:MGI Symbol;Acc... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|B7ZRU9|EVI1A_XENLA4.485e-733.33MDS1 and EVI1 complex locus protein EVI1-A OS=Xeno... [more]
sp|Q03112|MECOM_HUMAN5.423e-732.14Histone-lysine N-methyltransferase MECOM OS=Homo s... [more]
sp|B7ZRM8|EVI1B_XENLA5.653e-733.33MDS1 and EVI1 complex locus protein EVI1-B OS=Xeno... [more]
sp|P14404|MECOM_MOUSE6.389e-732.14Histone-lysine N-methyltransferase MECOM OS=Mus mu... [more]
sp|P26634|EGR2_CERTH1.547e-642.86E3 SUMO-protein ligase EGR2 (Fragment) OS=Cerdocyo... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3NNP27.917e-4557.59Uncharacterized protein (Fragment) OS=Schistocepha... [more]
A0A430QNM51.124e-4258.60Ras-responsive element-binding protein 1 OS=Schist... [more]
A0A095C1T41.125e-4258.60Ras-responsive element-binding protein 1 OS=Schist... [more]
A0A5K4FBW21.170e-4258.60Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A183QKD91.337e-4258.60Uncharacterized protein OS=Schistosoma rodhaini OX... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rreb1b5.864e-1536.28ras responsive element binding protein 1b [Source:... [more]
klf6a1.784e-742.59Kruppel like factor 6 [Source:NCBI gene;Acc:103031... [more]
klf6a2.022e-742.59Kruppel like factor 6 [Source:NCBI gene;Acc:103031... [more]
klf7b3.977e-742.59Krueppel-like factor 7 [Source:NCBI gene;Acc:10303... [more]
klf7a4.182e-742.59Krueppel-like factor 7 [Source:NCBI gene;Acc:10303... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egr2a1.817e-835.94early growth response 2a [Source:ZFIN;Acc:ZDB-GENE... [more]
ENSPMAT00000007831.16.273e-841.98pep scaffold:Pmarinus_7.0:GL477655:47469:47963:1 g... [more]
klf12b2.400e-742.31Kruppel-like factor 12b [Source:ZFIN;Acc:ZDB-GENE-... [more]
egr47.461e-746.94early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-... [more]
OVOL12.186e-638.78ovo like transcriptional repressor 1 [Source:HGNC ... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
USV11.845e-641.18Putative transcription factor containing a C2H2 zi... [more]
ZAP12.521e-638.46Zinc-regulated transcription factor; binds to zinc... [more]
TDA93.949e-630.10Transcription factor that regulates acetate produc... [more]
ADR15.197e-628.30Carbon source-responsive zinc-finger transcription... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO451994.050e-1141.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO404834.803e-1044.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO452552.687e-939.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO294631.538e-842.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO262211.802e-837.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rreb1a1.913e-1562.50ras responsive element binding protein 1 [Source:N... [more]
rreb1a2.031e-1562.50ras responsive element binding protein 1 [Source:N... [more]
mecom4.573e-928.68MDS1 and EVI1 complex locus [Source:NCBI gene;Acc:... [more]
mecom4.824e-928.68MDS1 and EVI1 complex locus [Source:NCBI gene;Acc:... [more]
mecom4.890e-928.68MDS1 and EVI1 complex locus [Source:NCBI gene;Acc:... [more]
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BLAST of Ras-responsive element-binding protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000027936.19.758e-799.10SMESG000027936.1[more]
SMESG000027936.11.022e-699.10SMESG000027936.1[more]
SMESG000059614.14.514e-5058.67SMESG000059614.1[more]
SMESG000028951.12.838e-946.81SMESG000028951.1[more]
SMESG000059642.16.258e-846.81SMESG000059642.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005992 ID=SMED30005992|Name=Ras-responsive element-binding protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1506bp
ATGTACAAATATTGTTGTTCGAAAGAAAAAAATGAAACACTGAAAATTGT
GTCATCATTTGTAATTTTTATGGGTGTAACTAGATTTAGAATTCTTCTAG
AAACATCTCAAAGTCGATATGGAAACTATTTTATGTTGATCATTTCGTTT
CAATCATTGCTAGCTTTACAAAATTGCAATAGATCCAACAAGAAAGAATT
GAAGTATTGCATTTTTAAATTTTGTAATTGTAAATACCGATCAAAATTTA
AATTAATTCGTCACATCAAAAATTCCCACATGAAACATATATACAACGTC
AACTCTCAGTCTTCCCCTATTATTGAGCCTCTAAATCTTTGTATCAAATC
TACTAATATCCCAAATTCATTTGTGTCACCCCCTGAAAGTCTCGGTACTC
AGTCAGAATTGAGAGCAATTCAACTAGATAAATTTGAACTCAATTATCTC
AATCCGAACTTTCAACAAAAGTTTTCAGACAAAATCCTCGATTTCTCAAC
AAATCGAAACTCACAATGGAATTTTGAAAAATCTCTTTTGTCGAAAATAT
CACCAATTACAGCTGCGATCCAATCATTCCAGTCTACTAACCAATTCATA
TCTTCGTCACCTCTGCTCACTGCTTCGCCGATATCCTTATCAAGTCCTTT
CAAATCCGATTGGAATGGACTGAATAAACTTGACTTCAACGACAACAACA
TGACACATTTGGATTCCCGGTCACCGAAATCGGATATAAGTCACACTCAA
ATTACTAACCTTTCAACAAAATCCTGCGTAAATACGACAATTGACGCCAT
AGCCAAGAATGCTATAGAGCATTTGTCATCCAAATCTATTGCATCTGATT
TTGCTAATTCGAATCCATTATTGGAGGATATGAAATCAAAGTATAACACA
TCAAATAAAAAGAAAAACTCATATAAAGATGCTCCAAAATTGATAACTTG
TCCAATGGAAGGATGTGCTCAGAAATTTCCGTGGAACAGTTCTTTAATGA
GGCATATTCTAACTCATACAGCCCACAAACCTTTCAAATGCACGAGATGT
ACCAAATGTTTTTCAACAAAGTCCAATAGAGAACGACATATGACTCGAGT
TCATGGGGTTCGAATCAACAGGTCTAAATTCAAGTCCATTCAAGCCGCCA
AAGCTACCTTTGAAGAGTCCTCGAAACTTATAGATGAAAATGCTGATTCC
GAAAATGGAAATTTAGTCGATGAAACTATTTTCCCAAACGATAAGGAAAT
AAACATAACGGAATTGAGTGAAGAAGAATGGATAATAATGGACAATAATG
ACCGAAGAGCTGAGGATATTAGTAATAATTTATTGAAGCTAGCCGGTCAG
CCACTGGTGGAACCAAATCCCGTTCGACTGAACAACAATCAAATTTCGTT
ACTAGAGAAATCTTTATCTCCAAAATCAGAATTTTCCTCCAAACCTTGCC
ATTCTATTTCTAAAGAGCGATTTTATTTAGACAGCTGTTTTTAGATGATT
GTATTA
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protein sequence of SMED30005992-orf-1

>SMED30005992-orf-1 ID=SMED30005992-orf-1|Name=SMED30005992-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=498bp
MYKYCCSKEKNETLKIVSSFVIFMGVTRFRILLETSQSRYGNYFMLIISF
QSLLALQNCNRSNKKELKYCIFKFCNCKYRSKFKLIRHIKNSHMKHIYNV
NSQSSPIIEPLNLCIKSTNIPNSFVSPPESLGTQSELRAIQLDKFELNYL
NPNFQQKFSDKILDFSTNRNSQWNFEKSLLSKISPITAAIQSFQSTNQFI
SSSPLLTASPISLSSPFKSDWNGLNKLDFNDNNMTHLDSRSPKSDISHTQ
ITNLSTKSCVNTTIDAIAKNAIEHLSSKSIASDFANSNPLLEDMKSKYNT
SNKKKNSYKDAPKLITCPMEGCAQKFPWNSSLMRHILTHTAHKPFKCTRC
TKCFSTKSNRERHMTRVHGVRINRSKFKSIQAAKATFEESSKLIDENADS
ENGNLVDETIFPNDKEINITELSEEEWIIMDNNDRRAEDISNNLLKLAGQ
PLVEPNPVRLNNNQISLLEKSLSPKSEFSSKPCHSISKERFYLDSCF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR036236Znf_C2H2_sf
IPR015880Znf_C2H2-like
IPR013087Znf_C2H2_type
IPR007087Znf_C2H2
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013087Zinc finger C2H2-typeSMARTSM00355c2h2final6coord: 315..339
e-value: 0.012
score: 24.8
coord: 68..93
e-value: 14.0
score: 11.9
coord: 345..368
e-value: 0.044
score: 22.9
IPR013087Zinc finger C2H2-typePFAMPF00096zf-C2H2coord: 345..368
e-value: 0.0012
score: 19.2
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 347..368
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 317..339
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 345..368
score: 10.512
IPR013087Zinc finger C2H2-typePROSITEPS50157ZINC_FINGER_C2H2_2coord: 315..344
score: 11.593
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 345..369
e-value: 2.8E-6
score: 29.2
NoneNo IPR availableGENE3DG3DSA:3.30.160.60coord: 263..344
e-value: 4.4E-7
score: 32.3
NoneNo IPR availablePANTHERPTHR46451FAMILY NOT NAMEDcoord: 75..399
IPR036236Zinc finger C2H2 superfamilySUPERFAMILYSSF57667beta-beta-alpha zinc fingerscoord: 326..368