Caspase-3B

Overview
NameCaspase-3B
Smed IDSMED30005973
Length (bp)894
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Caspase-3B (SMED30005973) t-SNE clustered cells

Violin plots show distribution of expression levels for Caspase-3B (SMED30005973) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Caspase-3B (SMED30005973) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Caspase-3B (SMED30005973) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005973

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30005973SMESG000053164.1 SMESG000053156.1 SMESG000053146.1 dd_Smed_v4_3121_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30005973SMESG000053164.1 SMESG000053156.1 SMESG000053146.1 dd_Smed_v4_3121_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30005973SMESG000053164.1 SMESG000053156.1 SMESG000053146.1 dd_Smed_v4_3121_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30005973SMESG000053164.1 SMESG000053156.1 SMESG000053146.1 dd_Smed_v6_3121_1_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30005973SMESG000053164.1 SMESG000053156.1 SMESG000053146.1 dd_Smed_v4_3121_1_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Caspase-3B vs. Ensembl Human
Match: CASP3 (caspase 3 [Source:HGNC Symbol;Acc:HGNC:1504])

HSP 1 Score: 201.445 bits (511), Expect = 6.908e-63
Identity = 100/235 (42.55%), Postives = 140/235 (59.57%), Query Frame = 2 
Query:  104 DMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSS-NIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            D  +  LC+IINN+ FH    +  R GT+ D   L+  F  L Y   +  ++T   +  +++ +S ++D    S+ V ++LSHG +GII+G +GPV L ++  +F+GD+CR L GKPK+F IQACRG + D G+  D GV       KIP+EADFL  YST PGY+SWRN   GSW+IQSLC  L++Y    + + IL +VN  VAT F S +   +     QI   V ML K L
Sbjct:   40 DYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVS-KEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKEL 273
[Close]
BLAST of Caspase-3B vs. Ensembl Human
Match: CASP3 (caspase 3 [Source:HGNC Symbol;Acc:HGNC:1504])

HSP 1 Score: 201.445 bits (511), Expect = 6.908e-63
Identity = 100/235 (42.55%), Postives = 140/235 (59.57%), Query Frame = 2 
Query:  104 DMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSS-NIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            D  +  LC+IINN+ FH    +  R GT+ D   L+  F  L Y   +  ++T   +  +++ +S ++D    S+ V ++LSHG +GII+G +GPV L ++  +F+GD+CR L GKPK+F IQACRG + D G+  D GV       KIP+EADFL  YST PGY+SWRN   GSW+IQSLC  L++Y    + + IL +VN  VAT F S +   +     QI   V ML K L
Sbjct:   40 DYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVS-KEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKEL 273
[Close]
BLAST of Caspase-3B vs. Ensembl Human
Match: CASP7 (caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508])

HSP 1 Score: 193.356 bits (490), Expect = 9.477e-60
Identity = 98/241 (40.66%), Postives = 146/241 (60.58%), Query Frame = 2 
Query:  101 YDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE-----KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            Y+M+ +KL  C+IINN+ F     +  R GT+ D   L   F  L +    Y + +   M ++L++ S+ +D  N +    I+LSHG + +IYG DG   +  L  +F+GD+C+ L+ KPK+FFIQACRG + D G+ AD    ++ +     KIP+EADFL  YSTVPGY+SWR+ G GSW++Q+LC  LE++ K  +++QIL +VN+ VA +F S ++        QI   V ML K L
Sbjct:   35 YNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASE-EDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKEL 274
[Close]
BLAST of Caspase-3B vs. Ensembl Human
Match: CASP7 (caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508])

HSP 1 Score: 193.741 bits (491), Expect = 1.457e-59
Identity = 98/241 (40.66%), Postives = 146/241 (60.58%), Query Frame = 2 
Query:  101 YDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE-----KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            Y+M+ +KL  C+IINN+ F     +  R GT+ D   L   F  L +    Y + +   M ++L++ S+ +D  N +    I+LSHG + +IYG DG   +  L  +F+GD+C+ L+ KPK+FFIQACRG + D G+ AD    ++ +     KIP+EADFL  YSTVPGY+SWR+ G GSW++Q+LC  LE++ K  +++QIL +VN+ VA +F S ++        QI   V ML K L
Sbjct:   60 YNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASE-EDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKEL 299
[Close]
BLAST of Caspase-3B vs. Ensembl Human
Match: CASP7 (caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508])

HSP 1 Score: 193.741 bits (491), Expect = 1.457e-59
Identity = 98/241 (40.66%), Postives = 146/241 (60.58%), Query Frame = 2 
Query:  101 YDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE-----KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            Y+M+ +KL  C+IINN+ F     +  R GT+ D   L   F  L +    Y + +   M ++L++ S+ +D  N +    I+LSHG + +IYG DG   +  L  +F+GD+C+ L+ KPK+FFIQACRG + D G+ AD    ++ +     KIP+EADFL  YSTVPGY+SWR+ G GSW++Q+LC  LE++ K  +++QIL +VN+ VA +F S ++        QI   V ML K L
Sbjct:   60 YNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASE-EDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKEL 299
[Close]
BLAST of Caspase-3B vs. Ensembl Celegans
Match: ced-3 (Cell death protein 3 Cell death protein 3 subunit p17 Cell death protein 3 subunit p15 Cell death protein 3 subunit p13 [Source:UniProtKB/Swiss-Prot;Acc:P42573])

HSP 1 Score: 125.561 bits (314), Expect = 6.283e-34
Identity = 76/252 (30.16%), Postives = 126/252 (50.00%), Query Frame = 2 
Query:  110 SKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDG-PVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKG--VL--ADGVHS---------------------SNIEKI----PIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISS 775
            S + +C+IINNE F     +  R GT+ D + L ++F  + YT     N+T   M   ++  ++ +   +  + +++ILSHG + +I GVD  P+    ++          L  KPK+ F+QACRG++ D G  VL   DGV +                       ++++    P +AD LI Y+T   Y SWRN   GSW+IQ++C+    + K  D+V++L +VN  VA  F++   S     M +++S
Sbjct:   24 SPRGMCLIINNEHFE---QMPTRNGTKADKDNLTNLFRCMGYTVICKDNLTGRGMLLTIRDFAKHES--HGDSAILVILSHGEENVIIGVDDIPISTHEIYDLLNAANAPRLANKPKIVFVQACRGERRDNGFPVLDSVDGVPAFLRRGWDNRDGPLFNFLGCVRPQVQQVWRKKPSQADILIAYATTAQYVSWRNSARGSWFIQAVCEVFSTHAKDMDVVELLTEVNKKVACGFQTSQGSNILKQMPEMTS 270
[Close]
BLAST of Caspase-3B vs. Ensembl Celegans
Match: ced-3 (Cell death protein 3 Cell death protein 3 subunit p17 Cell death protein 3 subunit p15 Cell death protein 3 subunit p13 [Source:UniProtKB/Swiss-Prot;Acc:P42573])

HSP 1 Score: 125.946 bits (315), Expect = 1.381e-32
Identity = 76/252 (30.16%), Postives = 126/252 (50.00%), Query Frame = 2 
Query:  110 SKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDG-PVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKG--VL--ADGVHS---------------------SNIEKI----PIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISS 775
            S + +C+IINNE F     +  R GT+ D + L ++F  + YT     N+T   M   ++  ++ +   +  + +++ILSHG + +I GVD  P+    ++          L  KPK+ F+QACRG++ D G  VL   DGV +                       ++++    P +AD LI Y+T   Y SWRN   GSW+IQ++C+    + K  D+V++L +VN  VA  F++   S     M +++S
Sbjct:  240 SPRGMCLIINNEHFE---QMPTRNGTKADKDNLTNLFRCMGYTVICKDNLTGRGMLLTIRDFAKHES--HGDSAILVILSHGEENVIIGVDDIPISTHEIYDLLNAANAPRLANKPKIVFVQACRGERRDNGFPVLDSVDGVPAFLRRGWDNRDGPLFNFLGCVRPQVQQVWRKKPSQADILIAYATTAQYVSWRNSARGSWFIQAVCEVFSTHAKDMDVVELLTEVNKKVACGFQTSQGSNILKQMPEMTS 486
[Close]
BLAST of Caspase-3B vs. Ensembl Celegans
Match: csp-1 (Caspase A Caspase A subunit p16 Caspase A subunit p14 [Source:UniProtKB/Swiss-Prot;Acc:G5EBM1])

HSP 1 Score: 101.293 bits (251), Expect = 5.622e-25
Identity = 66/221 (29.86%), Postives = 111/221 (50.23%), Query Frame = 2 
Query:  128 VIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGS-DGIIYGVDG-PVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIE-------------------ADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFR 727
            +I++NE F    N++ R GT+ D   L  +F KL YT     N+ + +M   L+ + +  ++ +  +I++ +LSHG   G ++G+D  PV +  +  Y    +   L+ KPK   + ACRG K + GV  DG+ +   +  PI                    AD +I +ST  G+ S+R+   G+WYI+S+C+   K+ KT  L+ IL +    V T + 
Sbjct:   28 LILSNENFK---NMERRVGTKQDEVNLTKLFQKLQYTVICKRNLEAESM---LEAIKEFAEMAHTDSIILFLLSHGDGAGSVFGIDDMPVNVMEVSTYLAYHQ--NLLLKPKWVAVSACRGGKLNMGVPVDGLPALEDKCAPISKFWNLMMSRIMPGTFTSLNADVIISFSTTDGFTSYRDEEAGTWYIKSMCKVFNKHSKTMHLLDILTETGRNVVTKYE 240
[Close]
BLAST of Caspase-3B vs. Ensembl Celegans
Match: csp-1 (Caspase A Caspase A subunit p16 Caspase A subunit p14 [Source:UniProtKB/Swiss-Prot;Acc:G5EBM1])

HSP 1 Score: 100.908 bits (250), Expect = 9.880e-24
Identity = 66/221 (29.86%), Postives = 111/221 (50.23%), Query Frame = 2 
Query:  128 VIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGS-DGIIYGVDG-PVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIE-------------------ADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFR 727
            +I++NE F    N++ R GT+ D   L  +F KL YT     N+ + +M   L+ + +  ++ +  +I++ +LSHG   G ++G+D  PV +  +  Y    +   L+ KPK   + ACRG K + GV  DG+ +   +  PI                    AD +I +ST  G+ S+R+   G+WYI+S+C+   K+ KT  L+ IL +    V T + 
Sbjct:  296 LILSNENFK---NMERRVGTKQDEVNLTKLFQKLQYTVICKRNLEAESM---LEAIKEFAEMAHTDSIILFLLSHGDGAGSVFGIDDMPVNVMEVSTYLAYHQ--NLLLKPKWVAVSACRGGKLNMGVPVDGLPALEDKCAPISKFWNLMMSRIMPGTFTSLNADVIISFSTTDGFTSYRDEEAGTWYIKSMCKVFNKHSKTMHLLDILTETGRNVVTKYE 508
[Close]
BLAST of Caspase-3B vs. Ensembl Celegans
Match: csp-2 (Putative inactive caspase B Putative inactive caspase B subunit p31 Putative inactive caspase B subunit p17 Putative inactive caspase subunit p14 [Source:UniProtKB/Swiss-Prot;Acc:Q9TZP5])

HSP 1 Score: 94.7449 bits (234), Expect = 1.092e-22
Identity = 63/220 (28.64%), Postives = 107/220 (48.64%), Query Frame = 2 
Query:  128 VIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDG-PVQLDRLFGYFKGDKCRG-LIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIP-----------------IEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRS 730
            +IINN  F     ++ R G++ D   L  +F +L Y + SY N+ S  +   +++ +Q     +  ++++ I+SHG  G++YGVDG PVQ+  +        C   L  KPK      CRG + D+ V  DG   +  ++ P                  +AD L+ +ST PG+ S+R+   G+WYIQ L + + +  K   L  +L++ N  V   + +
Sbjct:   29 IIINNVVF---CGMEKRIGSDKDKKKLSKLFERLGYQSTSYDNLKSSEILETVRQFTQSN---HGDSLIITIMSHGDQGLLYGVDGVPVQMLDIIDLM----CTASLAKKPKWLMCVCCRGDRIDRAVRCDGFIDNFFDRFPKFFQFMKSKFPSHQTSSSQADLLVSFSTSPGFLSFRDETKGTWYIQELYRVIIENAKDTHLADLLMETNRRVVEKYEA 238
[Close]
BLAST of Caspase-3B vs. Ensembl Fly
Match: Dcp-1 (gene:FBgn0010501 transcript:FBtr0072062)

HSP 1 Score: 157.532 bits (397), Expect = 9.292e-46
Identity = 97/249 (38.96%), Postives = 133/249 (53.41%), Query Frame = 2 
Query:   92 SKSYDMS-KQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDL--VNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGV-LADGV-----HSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFS-TDGMVQISSFVCMLRKSLQI 808
            +  Y+MS K +   +I N EF    +L+ R GT  D   LK  F  L +    + +     + +IL+ + +  +L   +   + V ILSHG  G +Y  D   +LD ++ YF    C  L GKPK+FFIQAC+G + D G+ L  GV      SS   KIPI ADFL  YST+PGYFSWRN   GSWY+QSL +EL    K +DL+ +L  VN  VA +F S+  +    D   QI     ML + L+ 
Sbjct:   68 ASEYNMSHKHRGVALIFNHEFFDIPSLKSRTGTNVDAQELKKAFENLGFAVSVHKDC---KLRDILKHVGKAAELDHTDNDCLAVAILSHGEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQGDRLDGGITLEKGVTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQKQIPCLTSMLTRILRF 313
[Close]
BLAST of Caspase-3B vs. Ensembl Fly
Match: Drice (gene:FBgn0019972 transcript:FBtr0085482)

HSP 1 Score: 148.673 bits (374), Expect = 3.691e-42
Identity = 89/236 (37.71%), Postives = 126/236 (53.39%), Query Frame = 2 
Query:  122 LCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVL-------ADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHT-NSFSTDGMVQISSFVCMLRKSLQ 805
            + +I N+E F     L+ R GT  D   L  V  +L++    Y +    ++   ++  +  Q+  +   I+V ILSHG  G IY  D   +LD ++ +F  + C  L GKPK+FFIQAC+G + D GV         DG  SS   KIP+ ADFLI YSTVPG++SWRN   GSW++QSLC EL    K  D++ +L  V   VA +F S T ++       QI     ML + L+
Sbjct:   95 MALIFNHEHFEVP-TLKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDILRTIE-YAASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDG-DSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTRILR 327
[Close]
BLAST of Caspase-3B vs. Ensembl Fly
Match: Decay (gene:FBgn0028381 transcript:FBtr0083304)

HSP 1 Score: 127.102 bits (318), Expect = 3.359e-34
Identity = 77/260 (29.62%), Postives = 136/260 (52.31%), Query Frame = 2 
Query:  110 SKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE--------------KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTH-------DLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQI-V*PKV 823
            ++  + +I+N+++   Q   + R GTE D + +++      +   ++ ++T   + + L+ ++ R+D       V+ ++SHG++G +Y  D    ++RL+  F GD C+ L  KPK+FFIQACRG   +K V          E               IP  AD L+ YST   +FS+RN   GSW+IQSLC+ L++            +L+++L  VN  VA  ++S+T + + + M ++ +F+  L K+ Q+ V PK 
Sbjct:   53 ARAGIALILNHKDVKGQ---KQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVA-REDHSQNDCFVLAVMSHGTEGKVYAKDMSYPVERLWNPFLGDNCKTLKNKPKLFFIQACRGANLEKAVEFSSFAVMTRELVPEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFIQSLCRVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMSTLTKTFQLRVKPKT 308
[Close]
BLAST of Caspase-3B vs. Ensembl Fly
Match: Dronc (gene:FBgn0026404 transcript:FBtr0076347)

HSP 1 Score: 98.9821 bits (245), Expect = 3.764e-23
Identity = 63/218 (28.90%), Postives = 101/218 (46.33%), Query Frame = 2 
Query:  176 RKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGS-----DGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYD------KGVLADGVHSSNIEK---------------IPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFST 751
            R G E D   L  +F +LN+T   Y NV     + +L  ++    + N    V+++++HG+     + + +     V + ++  +F+  KC  L+ KPKV     CRG +YD      +G L + V+++  EK               +P  AD L+ Y+  PGY + R+   GSWYIQ  CQ +  +    DL  IL K +  V  N R+   S  T
Sbjct:  213 RIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVG-NKRTKKGSMQT 429
[Close]
BLAST of Caspase-3B vs. Ensembl Fly
Match: Damm (gene:FBgn0033659 transcript:FBtr0088061)

HSP 1 Score: 80.1073 bits (196), Expect = 2.437e-17
Identity = 62/202 (30.69%), Postives = 94/202 (46.53%), Query Frame = 2 
Query:  131 IINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGS--------DGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTV 712
            I+N+E+F PQ +   RKG+ ND N L+  F  L    +  +N    ++ N ++  S ++     +  V+ ILSHG         D   Y +D     D LF  F+      L GKPK+  +QAC+G      + AD    +N         ++  YS   GY S+RN   GS +IQ+LC+ +++Y  T D   I   V   V
Sbjct:   42 ILNHEQF-PQDSQLNRKGSSNDVNALRKTFESLKCRVEVISNPALPDVKNKVKEWSAKR-FTQDAGFVLFILSHGDRKEKILACDHREYHLDD----DVLFPLFRNP---TLSGKPKILIVQACKG-----PLRADAKKMNN-------EPYIKCYSCSEGYLSYRNENHGSVFIQTLCEAMDQYGLTRDFQSIFKHVKAEV 222
[Close]
BLAST of Caspase-3B vs. Ensembl Zebrafish
Match: casp3b (caspase 3, apoptosis-related cysteine peptidase b [Source:ZFIN;Acc:ZDB-GENE-070607-1])

HSP 1 Score: 215.312 bits (547), Expect = 1.936e-68
Identity = 100/226 (44.25%), Postives = 140/226 (61.95%), Query Frame = 2 
Query:  125 CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            C+IINN+ FH +  +  R GT+ D   +   F++L +    Y ++T   M  +L + SQ +D    +    ++LSHG DG+IYG D  ++L RLF +F+GD+C  L+GKPK+FFIQACRG   D G+  DGV     ++IP+EADFL  YST PGY++WRN   GSW+I SLC  L KY K  +++Q++ +VN+ VA  F S +N    DG  QI   V ML K L
Sbjct:   57 CLIINNKNFHKRTGMGVRNGTDEDAKKVFETFSQLGFKVGHYNDLTVSQMMALLNKASQ-EDHSKSAMFACVLLSHGDDGLIYGTDNSIELKRLFAHFRGDRCTSLVGKPKLFFIQACRGTDLDSGIECDGVGDEETQRIPVEADFLYAYSTAPGYYAWRNVANGSWFISSLCDMLLKYGKQLEIMQVMTRVNHKVALEFESSSNLPGFDGKKQIPCIVSMLTKEL 281
[Close]
BLAST of Caspase-3B vs. Ensembl Zebrafish
Match: casp7 (caspase 7, apoptosis-related cysteine peptidase [Source:ZFIN;Acc:ZDB-GENE-050522-506])

HSP 1 Score: 203.371 bits (516), Expect = 5.425e-63
Identity = 106/244 (43.44%), Postives = 146/244 (59.84%), Query Frame = 2 
Query:  101 YDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSSNIE-------KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            Y MS Q++  C+IINN+ F  +  +  R GT+ D   L   F  L +    Y + T  NM  +L+ +S+ +D  + S    I+LSHG +G+IYG DG + +  +   FKGD C+ L+GKPK+FFIQACRG ++D GV  D G  +  IE       KIP+EADFL  YSTVPGY+SWRN G GSW++Q+LC  L ++ K  +++QIL +VN  VAT+F S +         QI   V ML K L
Sbjct:  105 YKMSHQRVGKCIIINNKNFDEKTGMNVRNGTDRDAGELFKCFKSLGFDVAVYNDQTCRNMERLLKAVSE-EDHSDSSCFACILLSHGEEGMIYGTDGAMPIKTMTSLFKGDVCKSLVGKPKLFFIQACRGSEFDDGVQTDSGPPNDTIETDANPRHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLSEFGKQLEIMQILTRVNYMVATSFESWSEDPRFSEKKQIPCVVSMLTKEL 347
[Close]
BLAST of Caspase-3B vs. Ensembl Zebrafish
Match: casp3a (caspase 3, apoptosis-related cysteine peptidase a [Source:ZFIN;Acc:ZDB-GENE-011210-1])

HSP 1 Score: 199.134 bits (505), Expect = 4.058e-62
Identity = 98/230 (42.61%), Postives = 138/230 (60.00%), Query Frame = 2 
Query:  125 CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE----KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            C+IINN+ F  +  + PR GT+ D   + +VF KL Y    Y + T   +  +L  ++   D    +++V ++LSHG +G+ +G D  V L  L   F+GD+C  L+GKPK+FFIQACRG + D GV  D     +I     +IP+EADFL  YSTVPGY+SWRN   GSW+IQSLC+ + KY    +L+QI+ +VN+ VA +F S +N    D   QI   V ML K +
Sbjct:   50 CIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGYIVKVYNDQTVAQIMQVLTTVAH-DDHSRCASLVCVLLSHGDEGVFFGTDTSVDLKSLTSLFRGDRCPSLVGKPKLFFIQACRGTELDPGVETDHPDHPDIPDGRVRIPVEADFLYAYSTVPGYYSWRNTMTGSWFIQSLCEMMTKYGSELELLQIMTRVNHKVALDFESTSNMPGFDAKKQIPCIVSMLTKEM 278
[Close]
BLAST of Caspase-3B vs. Ensembl Zebrafish
Match: casp3a (caspase 3, apoptosis-related cysteine peptidase a [Source:ZFIN;Acc:ZDB-GENE-011210-1])

HSP 1 Score: 199.134 bits (505), Expect = 4.058e-62
Identity = 98/230 (42.61%), Postives = 138/230 (60.00%), Query Frame = 2 
Query:  125 CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE----KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            C+IINN+ F  +  + PR GT+ D   + +VF KL Y    Y + T   +  +L  ++   D    +++V ++LSHG +G+ +G D  V L  L   F+GD+C  L+GKPK+FFIQACRG + D GV  D     +I     +IP+EADFL  YSTVPGY+SWRN   GSW+IQSLC+ + KY    +L+QI+ +VN+ VA +F S +N    D   QI   V ML K +
Sbjct:   50 CIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGYIVKVYNDQTVAQIMQVLTTVAH-DDHSRCASLVCVLLSHGDEGVFFGTDTSVDLKSLTSLFRGDRCPSLVGKPKLFFIQACRGTELDPGVETDHPDHPDIPDGRVRIPVEADFLYAYSTVPGYYSWRNTMTGSWFIQSLCEMMTKYGSELELLQIMTRVNHKVALDFESTSNMPGFDAKKQIPCIVSMLTKEM 278
[Close]
BLAST of Caspase-3B vs. Ensembl Zebrafish
Match: casp6b.2 (caspase 6b.2, apoptosis-related cysteine peptidase [Source:ZFIN;Acc:ZDB-GENE-060312-12])

HSP 1 Score: 152.91 bits (385), Expect = 1.039e-44
Identity = 86/240 (35.83%), Postives = 128/240 (53.33%), Query Frame = 2 
Query:  110 SKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE---------KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            +K+ L +I N ++F   L L+ RKGT+ D + L S F +L++   +Y + +   +   ++ ++   D V+    V I LSHG DG +Y  D  +++  +   FKGDKCRGL+GKPK+F  QACRG K D  V       S+ E          +P  ADF++ YST  G+ S+R+   G+WYIQ LC+ + +Y    +   IL  VN  V+   RS  +  S  G  Q+  F  ML K L
Sbjct:    4 AKRGLALIFNQKDFS-LLGLKTRKGTDKDRDSLVSRFEELDFEVKAYNDYSRDKVLKEIKEVAA-ADHVDADCFVCIFLSHGEDGHVYANDEKIKIPEITDLFKGDKCRGLVGKPKIFIWQACRGDKKDDPVAPMSAEDSDDEMAVDAGVSNTLPAGADFIMCYSTTEGFCSFRDPLNGTWYIQDLCEIMGRYRSQLEFTNILTLVNRKVS--LRSICDDLSATGTKQMPCFASMLTKRL 239
[Close]
BLAST of Caspase-3B vs. Ensembl Xenopus
Match: casp3.2 (caspase 3, gene 2 [Source:NCBI gene;Acc:100151728])

HSP 1 Score: 202.601 bits (514), Expect = 2.671e-63
Identity = 101/235 (42.98%), Postives = 143/235 (60.85%), Query Frame = 2 
Query:  104 DMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHS--SNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            D  +  +C+IINN+ F    N+  R GT+ D   L   F  L Y      +  S++++ +L+++S+ +D    S+ V  ILSHG DG++YGVDGP+Q+  L   F+GD+C+ L+GKPK+FFIQACRG   D G+  D        I++IP+EADFL  YSTVPGY+SWRN   GSW+IQSLC+ ++ Y    +L+QIL  VN+ VA  F S +   +     QI   V ML K+ 
Sbjct:   51 DYPEMGICLIINNKNFQSSTNMGVRNGTDVDARKLHETFTGLGYKVKVCNDQKSNDIFTLLKKMSE-EDHSKRSSFVCAILSHGEDGLVYGVDGPIQIKNLTDLFRGDRCKTLVGKPKLFFIQACRGTDLDSGIETDSGSEPGEEIQRIPVEADFLYAYSTVPGYYSWRNTMNGSWFIQSLCEMIKLYGPHLELIQILTCVNHMVALEFESCSTQQAFHAKKQIPCVVSMLTKAF 284
[Close]
BLAST of Caspase-3B vs. Ensembl Xenopus
Match: ENSXETT00000003846.1 (caspase 3, gene 1 [Source:NCBI gene;Acc:100486222])

HSP 1 Score: 173.326 bits (438), Expect = 4.627e-52
Identity = 88/232 (37.93%), Postives = 139/232 (59.91%), Query Frame = 2 
Query:  113 KQK-LCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            KQK +C+I+  E+F      +  + + +D  +L ++F K+ +      N T+  + ++L+ ++ RQD       V +++SHG     Y  D   ++D L   F+G+ C+ LIGKPK+FFIQACRG K D GV+ D G+ ++    IP E DFL  Y+T PGYF+WR G  GSW+IQSLC+ L +Y++  DL+QIL +VN+ VA  + S++     +   +++ F+ ML K L
Sbjct:   38 KQKSICLILCMEKFDNDPKGKRSRNSNDDKIFLNNIFVKMGFEVRLEENKTADEIESLLKDIA-RQDHSERGCFVCVVISHGDKDFFYARDQEFKIDALAEPFRGENCKSLIGKPKLFFIQACRGDKTDSGVVKDAGIATTTASVIPTECDFLFAYATPPGYFAWRRGA-GSWFIQSLCEMLGEYWQKRDLLQILTRVNHKVAYEYISNSTDTDKNEKKEMTCFLSMLTKEL 267
[Close]
BLAST of Caspase-3B vs. Ensembl Xenopus
Match: lrrc38 (leucine rich repeat containing 38 [Source:Xenbase;Acc:XB-GENE-955337])

HSP 1 Score: 167.548 bits (423), Expect = 1.501e-49
Identity = 92/234 (39.32%), Postives = 131/234 (55.98%), Query Frame = 2 
Query:  125 CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSSNIE-------KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            C+IINN+ F     + PR GT+ D   L   F  L +    + N +   M  +L+ +++ QD  + +    I LSHG +G+IYG DG + +                GKPK+FFIQACRG ++D G+  D G  + ++E       KIP+EADFL  YSTVPGY+SWRN G GSW++Q+LC  L ++ K  +++QIL +VN  VAT F S+ +    +   QI   V ML K L
Sbjct:   72 CIIINNKNFDDITGMSPRNGTDIDARDLLRCFKGLGFDVTVFNNKSCTEMETLLRSVAE-QDHKDSACFACIFLSHGEEGLIYGTDGAMPIK---------------GKPKLFFIQACRGCEFDDGLETDAGPSNDSLETDANPRHKIPVEADFLYAYSTVPGYYSWRNPGRGSWFVQALCNVLNEHGKELEVMQILTRVNYLVATQFESYCDDPQFNKKKQIPCVVSMLTKEL 289
[Close]
BLAST of Caspase-3B vs. Ensembl Xenopus
Match: calb2 (calbindin 2 [Source:Xenbase;Acc:XB-GENE-960001])

HSP 1 Score: 154.066 bits (388), Expect = 2.355e-44
Identity = 93/268 (34.70%), Postives = 133/268 (49.63%), Query Frame = 2 
Query:   41 NTGVLDGDFMDIVDGGSSKSYDMSKQK--LCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVL----ADGVHSSNIEKI--------PIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            N    DG     ++   S  Y M+ ++  L +I N+E+F+ QL L  R+GT  D   L  +   L +   +Y N+ + ++   +Q  S   D  N    + + LSHG D  IY  D  + +  L   FKGDKC  L+GKPK+F  QACRG+K+D  VL     D V  +NI ++        P  ADF++ YS   GY+S R    GSWYIQ LC+ L+ +  + +  +IL  VN  V+    +  N     G  QI  F  ML K L
Sbjct:   31 NVAETDGWTSRTLELDPSAEYKMTHKRRGLALIFNHEDFYWQLRLGSRRGTNTDSMNLNRILTDLGFDVQNYYNLRTLDILEKIQEAST-ADHSNADCFLCVFLSHGEDRHIYSYDSLIDIQELTNSFKGDKCESLVGKPKIFIFQACRGEKHDNPVLPTDETDSVTLTNITEVDAASLYTLPAGADFIMCYSVAEGYYSHRETVNGSWYIQDLCEVLKAHAASLEFTEILTLVNRKVSQRSVAFCNDPKAIGKKQIPCFSSMLTKKL 297
[Close]
BLAST of Caspase-3B vs. Ensembl Xenopus
Match: bmt2 (base methyltransferase of 25S rRNA 2 homolog [Source:Xenbase;Acc:XB-GENE-999766])

HSP 1 Score: 130.954 bits (328), Expect = 4.739e-34
Identity = 88/257 (34.24%), Postives = 128/257 (49.81%), Query Frame = 2 
Query:   95 KSYDMSKQK--LCVIINNEEFHP----QLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGP-VQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE---------KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQIV*P 817
            ++Y + KQ    CV+INN +F            R+GT  D   +  +FN+  Y T+ + ++T+ N+   L+  S++ D     + V  ILSHG  G + G DG  V++ RL  YF G  C  LI KPK+FFIQAC+G++    V  +    S+            +P+EADFL  ++TV  Y S R+   GS YIQ LC+ L  +    DL+ +L  VNN VA              + Q+ SF   LRK L +  P
Sbjct:  248 ETYRLEKQPHGWCVVINNYDFREARSRDCKYSNREGTMKDAEDITKIFNERGYITEEHKDLTAENIRKTLEMYSKK-DHAENDSFVCFILSHGGIGTVCGCDGEEVEIKRLTKYFNGQHCPSLINKPKIFFIQACQGKESHPKVDINTDTESSFSFYEQDAMGTHLPLEADFLTAFATVEEYTSLRHIEKGSIYIQQLCKALTTHL-CQDLIDMLTFVNNEVAGMLF----PLGRKNVTQMPSFKSELRKKLVLPPP 498
[Close]
BLAST of Caspase-3B vs. Ensembl Mouse
Match: Casp3 (caspase 3 [Source:MGI Symbol;Acc:MGI:107739])

HSP 1 Score: 202.601 bits (514), Expect = 1.754e-63
Identity = 104/248 (41.94%), Postives = 144/248 (58.06%), Query Frame = 2 
Query:   77 VDGG----SSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNI--EKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            VD G    SS   D  +  +C+IINN+ FH    +  R GT+ D   L+  F  L Y   +  ++T  ++  ++  +S ++D    S+ V +ILSHG +G+IYG +GPV+L +L  +F+GD CR L GKPK+F IQACRG + D G+  D      +  +KIP+EADFL  YST PGY+SWRN   GSW+IQSLC  L+ Y    + + IL +VN  VAT F S +   +     QI   V ML K L
Sbjct:   27 VDSGIYLDSSYKMDYPEMGICIIINNKNFHKSTGMSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILELMDSVS-KEDHSKRSSFVCVILSHGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDEEMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSTFHAKKQIPCIVSMLTKEL 273
[Close]
BLAST of Caspase-3B vs. Ensembl Mouse
Match: Casp3 (caspase 3 [Source:MGI Symbol;Acc:MGI:107739])

HSP 1 Score: 202.601 bits (514), Expect = 1.754e-63
Identity = 104/248 (41.94%), Postives = 144/248 (58.06%), Query Frame = 2 
Query:   77 VDGG----SSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNI--EKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            VD G    SS   D  +  +C+IINN+ FH    +  R GT+ D   L+  F  L Y   +  ++T  ++  ++  +S ++D    S+ V +ILSHG +G+IYG +GPV+L +L  +F+GD CR L GKPK+F IQACRG + D G+  D      +  +KIP+EADFL  YST PGY+SWRN   GSW+IQSLC  L+ Y    + + IL +VN  VAT F S +   +     QI   V ML K L
Sbjct:   27 VDSGIYLDSSYKMDYPEMGICIIINNKNFHKSTGMSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILELMDSVS-KEDHSKRSSFVCVILSHGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDEEMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSTFHAKKQIPCIVSMLTKEL 273
[Close]
BLAST of Caspase-3B vs. Ensembl Mouse
Match: Casp7 (caspase 7 [Source:MGI Symbol;Acc:MGI:109383])

HSP 1 Score: 194.512 bits (493), Expect = 5.128e-60
Identity = 97/241 (40.25%), Postives = 145/241 (60.17%), Query Frame = 2 
Query:  101 YDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE-----KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            Y M  QK+  C+IINN+ F     +  R GT+ D   L   F  L +    + + +   M ++L++ S+ +D  N +    ++LSHG + +IYG DG   +  L  +F+GD+C+ L+ KPK+FFIQACRG + D G+ AD    ++I+     KIP+EADFL  YSTVPGY+SWRN G GSW++Q+LC  L ++ K  +++QIL +VN+ VA +F S ++    +   QI   V ML K L
Sbjct:   60 YRMDFQKMGKCIIINNKNFDKATGMDVRNGTDKDAGALFKCFQNLGFEVTVHNDCSCAKMQDLLRKASE-EDHSNSACFACVLLSHGEEDLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDIDANPRNKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILNEHGKDLEIMQILTRVNDRVARHFESQSDDPRFNEKKQIPCMVSMLTKEL 299
[Close]
BLAST of Caspase-3B vs. Ensembl Mouse
Match: Casp7 (caspase 7 [Source:MGI Symbol;Acc:MGI:109383])

HSP 1 Score: 149.828 bits (377), Expect = 1.454e-43
Identity = 75/181 (41.44%), Postives = 109/181 (60.22%), Query Frame = 2 
Query:  101 YDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIE-----KIPIEADFLIGYSTVPGYFSWRNGGIGS 622
            Y M  QK+  C+IINN+ F     +  R GT+ D   L   F  L +    + + +   M ++L++ S+ +D  N +    ++LSHG + +IYG DG   +  L  +F+GD+C+ L+ KPK+FFIQACRG + D G+ AD    ++I+     KIP+EADFL  YSTVPGY+SWRN G GS
Sbjct:   58 YRMDFQKMGKCIIINNKNFDKATGMDVRNGTDKDAGALFKCFQNLGFEVTVHNDCSCAKMQDLLRKASE-EDHSNSACFACVLLSHGEEDLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDIDANPRNKIPVEADFLFAYSTVPGYYSWRNPGKGS 237
[Close]
BLAST of Caspase-3B vs. Ensembl Mouse
Match: Casp6 (caspase 6 [Source:MGI Symbol;Acc:MGI:1312921])

HSP 1 Score: 143.28 bits (360), Expect = 1.245e-40
Identity = 79/264 (29.92%), Postives = 126/264 (47.73%), Query Frame = 2 
Query:   71 DIVDGGSSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLA--------------DGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQIV*PK 820
            ++ D       D  ++ + +I N+E F   L L  R+GT  D + L   F+ L +    + ++ +  +   +  +S     ++    + + LSHG    +Y  D  +++  L G FKGDKC+ L+GKPK+F IQACRG ++D  V+                 V ++++  +P  ADFL+ YS   GY+S R    GSWYIQ LC+ L +Y  + +  ++L  VN  V+             G  Q+  F  ML K L    PK
Sbjct:   12 EVFDPAEQYKMDHKRRGVALIFNHERFFWHLTLPERRGTNADRDNLTRRFSDLGFEVKCFNDLRAEELLLKIHEVSTSSH-IDADCFICVFLSHGEGNHVYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVVPLDMVDHQTDKLDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLARYGSSLEFTELLTLVNRKVSQRRVDFCKDPDAIGKKQVPCFASMLTKKLHFC-PK 273
[Close]
BLAST of Caspase-3B vs. UniProt/SwissProt
Match: sp|Q8MJU1|CASP3_FELCA (Caspase-3 OS=Felis catus OX=9685 GN=CASP3 PE=2 SV=1)

HSP 1 Score: 207.994 bits (528), Expect = 8.938e-65
Identity = 104/235 (44.26%), Postives = 139/235 (59.15%), Query Frame = 2 
Query:  104 DMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNI--EKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            D  +  LC+IINN+ FH    +  R GT+ D   L+  F  L Y   +  ++T   +  +L  +S R+D    S+ + ++LSHG +GIIYG +GPV L +L G+F+GD CR L GKPK+F IQACRG + D G+  D     +I  +KIP+EADFL  YST PGY+SWRN   GSW+IQSLC  L  Y    + + IL +VN  VAT F S +   +  G  QI   V ML K L
Sbjct:   40 DYPEMGLCIIINNKNFHESTGMPSRSGTDVDAANLRETFTNLKYEVRNKNDLTREQIVALLDSVS-REDHSKRSSFICVLLSHGEEGIIYGTNGPVDLKKLTGFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTEDDIACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLRLYAHELEFMHILTRVNRKVATEFESFSLDSAFHGKKQIPCIVSMLTKEL 273
[Close]
BLAST of Caspase-3B vs. UniProt/SwissProt
Match: sp|Q60431|CASP3_MESAU (Caspase-3 OS=Mesocricetus auratus OX=10036 GN=CASP3 PE=2 SV=1)

HSP 1 Score: 207.608 bits (527), Expect = 9.853e-65
Identity = 103/240 (42.92%), Postives = 142/240 (59.17%), Query Frame = 2 
Query:   89 SSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNI--EKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            SS   D  +  +C+IINN+ FH    + PR GT+ D   L+  F  L Y   +  ++T   +  +++  S ++D    S+ V +ILSHG +G+I+G DGP+ L +L  YF+GD CR LIGKPK+F IQACRG + D G+  D     ++  +KIP+EADFL  YST PGY+SWRN   GSW+IQSLC  L+ Y    + + IL +VN  VAT F S +   +     QI   V ML K L
Sbjct:   35 SSYKMDYPEMGVCIIINNKNFHKSTGMTPRSGTDVDAAKLRETFMALKYEVRNKNDLTREEIVELMKNAS-KEDHSKRSSFVCVILSHGDEGVIFGTDGPIDLKKLTSYFRGDYCRSLIGKPKLFIIQACRGTELDCGIETDSGTEDDMTCQKIPVEADFLYAYSTAPGYYSWRNPKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSTFHAKKQIPCIVSMLTKEL 273
[Close]
BLAST of Caspase-3B vs. UniProt/SwissProt
Match: sp|Q8MKI5|CASP3_CANLF (Caspase-3 OS=Canis lupus familiaris OX=9615 GN=CASP3 PE=2 SV=1)

HSP 1 Score: 206.068 bits (523), Expect = 4.994e-64
Identity = 102/237 (43.04%), Postives = 142/237 (59.92%), Query Frame = 2 
Query:  104 DMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSS-NIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQI 808
            D  +  LC+IINN+ FH    + PR GT+ D   L+  F  L Y   +  ++T   +  ++  +S ++D    S+ V ++LSHG +GII+G +GPV L ++ G+F+GD CR L GKPK+F IQACRG + D G+  D G+      +KIP+EADFL  YST PGY+SWRN   GSW+IQSLC  L+ Y    + + IL +VN  VAT F S +   +  G  QI   V ML K L +
Sbjct:   40 DYPEMGLCIIINNKNFHKSTGMAPRSGTDVDAANLRETFTNLKYEVRNKNDLTCEEILELMNSVS-KEDHSKRSSFVCVLLSHGDEGIIFGTNGPVDLRKVTGFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGIEDDMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSAFHGKKQIPCIVSMLTKELYL 275
[Close]
BLAST of Caspase-3B vs. UniProt/SwissProt
Match: sp|P70677|CASP3_MOUSE (Caspase-3 OS=Mus musculus OX=10090 GN=Casp3 PE=1 SV=1)

HSP 1 Score: 202.601 bits (514), Expect = 1.227e-62
Identity = 104/248 (41.94%), Postives = 144/248 (58.06%), Query Frame = 2 
Query:   77 VDGG----SSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNI--EKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            VD G    SS   D  +  +C+IINN+ FH    +  R GT+ D   L+  F  L Y   +  ++T  ++  ++  +S ++D    S+ V +ILSHG +G+IYG +GPV+L +L  +F+GD CR L GKPK+F IQACRG + D G+  D      +  +KIP+EADFL  YST PGY+SWRN   GSW+IQSLC  L+ Y    + + IL +VN  VAT F S +   +     QI   V ML K L
Sbjct:   27 VDSGIYLDSSYKMDYPEMGICIIINNKNFHKSTGMSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILELMDSVS-KEDHSKRSSFVCVILSHGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDEEMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSTFHAKKQIPCIVSMLTKEL 273
[Close]
BLAST of Caspase-3B vs. UniProt/SwissProt
Match: sp|P55213|CASP3_RAT (Caspase-3 OS=Rattus norvegicus OX=10116 GN=Casp3 PE=2 SV=2)

HSP 1 Score: 201.445 bits (511), Expect = 3.075e-62
Identity = 101/240 (42.08%), Postives = 140/240 (58.33%), Query Frame = 2 
Query:   89 SSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNI--EKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            SS   D  +  LC+IINN+ FH    +  R GT+ D   L+  F  L Y   +  ++T   +  ++  +S ++D    S+ V +ILSHG +G+I+G +GPV L +L  +F+GD CR L GKPK+F IQACRG + D G+  D     ++  +KIP+EADFL  YST PGY+SWRN   GSW+IQSLC  L+ Y    + + IL +VN  VAT F S +   +     QI   V ML K L
Sbjct:   35 SSYKMDYPEMGLCIIINNKNFHKSTGMSARNGTDVDAANLRETFMALKYEVRNKNDLTREEIMELMDSVS-KEDHSKRSSFVCVILSHGDEGVIFGTNGPVDLKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDDDMACQKIPVEADFLYAYSTAPGYYSWRNSRDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDATFHAKKQIPCIVSMLTKEL 273
[Close]
BLAST of Caspase-3B vs. TrEMBL
Match: A0A4Y6I1H4 (Caspase-3B OS=Dugesia japonica OX=6161 GN=cas-3B PE=2 SV=1)

HSP 1 Score: 356.681 bits (914), Expect = 6.385e-121
Identity = 171/250 (68.40%), Postives = 199/250 (79.60%), Query Frame = 2 
Query:   53 LDGDFMDIVDGGSSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            +D D +D VDG  + +YDMS++KLC II+NEEF P LNL  R GT+ DF  L+ VF  L +  + + N T   +   L++LSQR+DL  VS +V IILSHG +GIIYG DG V+LDRLFGYFKGDKC+GLIGKPK+FFIQACRGQKYDKGV AD + S+ IEKIPIEADFLIGYSTVPGYFSWRNG  GSWYIQ+LC+EL K  KTH+LVQ+LVKVNN VATNF+S TN   TDGMVQISSFVCMLRKSL
Sbjct:   11 IDTDDLDTVDGQENNAYDMSQKKLCYIISNEEFQPHLNLSTRSGTDKDFKQLRQVFKTLKFEVEPFKNCTCRQINENLKQLSQRKDLDGVSMMVCIILSHGDEGIIYGTDGIVELDRLFGYFKGDKCKGLIGKPKIFFIQACRGQKYDKGVSADSIISNYIEKIPIEADFLIGYSTVPGYFSWRNGASGSWYIQALCKELIKCSKTHELVQLLVKVNNNVATNFKSKTNQKETDGMVQISSFVCMLRKSL 260
[Close]
BLAST of Caspase-3B vs. TrEMBL
Match: A0A4Y6I1I1 (Caspase-3A OS=Dugesia japonica OX=6161 GN=cas-3A PE=2 SV=1)

HSP 1 Score: 329.331 bits (843), Expect = 2.839e-110
Identity = 154/248 (62.10%), Postives = 194/248 (78.23%), Query Frame = 2 
Query:   68 MDIVDGGSSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQIV 811
             D VDG   + YD+SK KLC IINNEEF+P+LNL  R GT+ DF  LK VF KL +  ++Y N     + + L+ LS+R++L +VS +V IIL+HG+DGIIYG+DGP++LDR+FGYFKGDKCR LIGKPKVF  QACRG+K+DKGV+ADG   +++EKIP+EADFLIGYSTV GYFSWRNG  GSWYIQ+LC+ELE+  ++ +L+Q+LV VNN VATN+ S T +  TD MVQI SFVCMLRK L +V
Sbjct:    9 FDDVDGTIRECYDVSKIKLCYIINNEEFYPKLNLPTRSGTDEDFKSLKQVFTKLGFKVENYKNFKKDEICSNLRELSERKELKDVSILVCIILTHGADGIIYGIDGPIELDRIFGYFKGDKCRKLIGKPKVFLFQACRGEKFDKGVVADGFFQTSLEKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQALCRELERSAQSMELIQLLVNVNNYVATNYFSMTKNDKTDAMVQIPSFVCMLRKPLWLV 256
[Close]
BLAST of Caspase-3B vs. TrEMBL
Match: A0A493QY72 (Caspase-7 OS=Dugesia japonica OX=6161 GN=CASP-7 PE=2 SV=1)

HSP 1 Score: 311.227 bits (796), Expect = 3.338e-103
Identity = 146/248 (58.87%), Postives = 182/248 (73.39%), Query Frame = 2 
Query:   68 MDIVDGGSSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQIV 811
            MD VD   S  Y   K+KLC IINNEEF   LNL PR GT+ DF  LK++F KLN+  +++ N T++ M   L+ +S+R+DL + S  V  ILSHG +GIIYG D  V +D +  YFKGDKC+GL+GKPK+FFIQACRG K+DKGVLAD V S+N++KIPIEAD LIGYSTVPGYFSWRN   GSWYIQ+LC E+EK  KT D+V ILV+VN +VA NF S+T    + GM+QI SF CMLRK + ++
Sbjct:    1 MDTVDAKESDFYSTDKKKLCYIINNEEFDRGLNLSPRSGTQRDFEKLKTLFKKLNFVVENHKNCTAYEMRKNLEEISKRKDLKDYSMFVCFILSHGDEGIIYGRDAHVSIDTMLNYFKGDKCKGLVGKPKLFFIQACRGDKFDKGVLADSVGSNNLDKIPIEADVLIGYSTVPGYFSWRNSSNGSWYIQALCSEIEKNAKTEDVVHILVRVNASVAGNFSSNTGDTKSHGMIQIPSFTCMLRKKVLLL 248
[Close]
BLAST of Caspase-3B vs. TrEMBL
Match: A0A4Y6I1G1 (Caspase-7 OS=Dugesia japonica OX=6161 GN=cas-7 PE=2 SV=1)

HSP 1 Score: 303.138 bits (775), Expect = 5.198e-100
Identity = 142/248 (57.26%), Postives = 179/248 (72.18%), Query Frame = 2 
Query:   68 MDIVDGGSSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQIV 811
            MD VD   S  Y   K+KLC IINNEEF   LNL  R GT+ DF  LK++F KLN+  +++ N T+  M   L+ +S+R+DL + S  V  ILSHG +GIIYG D  V +D +   FKGDKC+GL+GKPK+FFIQACRG ++DKGV+AD V S+N++KIPIEAD LIGYSTVPGYFSWRN   GSWYIQ+LC E+EK  +T D+V ILV+VN +VA NF S+T    + GM+QI SF CMLRK + +V
Sbjct:    1 MDTVDAKESDFYSTDKKKLCYIINNEEFDRTLNLSSRSGTQRDFEKLKTLFKKLNFVVENHKNCTAGEMRKNLEEISKRKDLKDYSMFVCFILSHGDEGIIYGRDAFVPIDSMLNLFKGDKCKGLVGKPKLFFIQACRGDRFDKGVVADSVGSNNLDKIPIEADVLIGYSTVPGYFSWRNSSNGSWYIQALCSEIEKNAETEDVVHILVRVNASVAANFSSNTGDIKSHGMIQIPSFTCMLRKKVLLV 248
[Close]
BLAST of Caspase-3B vs. TrEMBL
Match: A0A4Y6I0S1 (Caspase-3C OS=Dugesia japonica OX=6161 GN=cas-3C PE=2 SV=1)

HSP 1 Score: 226.098 bits (575), Expect = 7.095e-70
Identity = 115/245 (46.94%), Postives = 152/245 (62.04%), Query Frame = 2 
Query:   68 MDIVDGGSSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            M+  +  S + Y M+ +KLC IINNE FH +  L  R GT  DF  +K  F KLN+      N  S  M   LQ++S + DL + S  V +ILSHG +GIIYG +  V++++L   F  + C  L  KPK+F IQAC+G K D G  AD + S+NI K+ IE +F IGYSTVPGYFSWRN  +GSW+I SLC  +       DLVQ+LV+VNN V+  +RS+ N    +  +QISSFVCML K +
Sbjct:    1 MNFNNSNSRELYPMNGKKLCYIINNELFHKKSGLTRRNGTNIDFKNIKITFEKLNFEIQWNDNCRSLEMIQNLQKISLKSDLKDYSIFVCVILSHGDEGIIYGFEDSVEINKLLAIFTEENCEALRDKPKIFLIQACKGDKCDSGAYADSIQSNNINKMFIEPNFFIGYSTVPGYFSWRNQVVGSWFISSLCDVINSNENREDLVQLLVRVNNRVSK-YRSNVNRNDMNNKLQISSFVCMLLKDV 244
[Close]
BLAST of Caspase-3B vs. Ensembl Cavefish
Match: ENSAMXT00000034295.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001829.1:2219:15770:-1 gene:ENSAMXG00000030411.1 transcript:ENSAMXT00000034295.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 202.216 bits (513), Expect = 2.576e-63
Identity = 94/226 (41.59%), Postives = 136/226 (60.18%), Query Frame = 2 
Query:  125 CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            C+IINN+ FH    +  R GT+ D       F KL Y    + + T   +  +L  ++ R+D    +++V ++LSHG +G+ +G DG ++L  L   F+GD+C  L+GKPK+FFIQACRG   D G+  D     +  KIP+EADFL  YST PGY+SWRN   GSW++QSLC+ + KY +  +L+QI+ +VN  VA +F S +N+   D   QI   V ML K +
Sbjct:   61 CIIINNKNFHRSTGMNQRNGTDVDAGNAMKAFGKLGYKVKVFNDQTVDQIKQVLTAVA-REDHSRCASLVCVLLSHGDEGVFFGTDGALELKSLTSLFRGDRCTSLVGKPKLFFIQACRGTDLDAGIEMDSPPDGSPVKIPVEADFLYAYSTAPGYYSWRNTMTGSWFMQSLCEMVSKYGRELELMQIMTRVNYKVAMDFESASNAPGFDAKKQIPCIVSMLTKEM 285
[Close]
BLAST of Caspase-3B vs. Ensembl Cavefish
Match: ENSAMXT00000039856.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001829.1:7264:16104:-1 gene:ENSAMXG00000030411.1 transcript:ENSAMXT00000039856.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 201.445 bits (511), Expect = 4.252e-63
Identity = 94/226 (41.59%), Postives = 136/226 (60.18%), Query Frame = 2 
Query:  125 CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            C+IINN+ FH    +  R GT+ D       F KL Y    + + T   +  +L  ++ R+D    +++V ++LSHG +G+ +G DG ++L  L   F+GD+C  L+GKPK+FFIQACRG   D G+  D     +  KIP+EADFL  YST PGY+SWRN   GSW++QSLC+ + KY +  +L+QI+ +VN  VA +F S +N+   D   QI   V ML K +
Sbjct:   52 CIIINNKNFHRSTGMNQRNGTDVDAGNAMKAFGKLGYKVKVFNDQTVDQIKQVLTAVA-REDHSRCASLVCVLLSHGDEGVFFGTDGALELKSLTSLFRGDRCTSLVGKPKLFFIQACRGTDLDAGIEMDSPPDGSPVKIPVEADFLYAYSTAPGYYSWRNTMTGSWFMQSLCEMVSKYGRELELMQIMTRVNYKVAMDFESASNAPGFDAKKQIPCIVSMLTKEM 276
[Close]
BLAST of Caspase-3B vs. Ensembl Cavefish
Match: casp7 (caspase 7 [Source:NCBI gene;Acc:103041716])

HSP 1 Score: 199.134 bits (505), Expect = 1.884e-61
Identity = 103/244 (42.21%), Postives = 145/244 (59.43%), Query Frame = 2 
Query:  101 YDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSSNIE-------KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            Y MS +++  C+IINN+ F  +  +  R GT+ D   L   F  L +    Y + T   M  +L+ +S+ +D  + S    I+LSHG +G+IYG DG + +  +   F+GD C+ L+GKPK+FFIQACRG ++D G+  D G  +  IE       KIP+EADFL  YSTVPGY+SWRN G GSW++Q+LC  L ++ K  +++QIL +VN  VATNF S +         QI   V ML K L
Sbjct:   98 YKMSHRRVGKCIIINNKNFDEKTGMNVRNGTDRDAGELFKCFKNLGFDVFVYNDQTCAKMERLLKEVSE-EDHSDSSCFACILLSHGEEGMIYGTDGAMPIKSMTSLFRGDMCKSLVGKPKLFFIQACRGSEFDDGIQTDSGPPNDTIETDANPRHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLNEFGKQLEIMQILTRVNYMVATNFESWSEDPRFSEKKQIPCVVSMLTKEL 340
[Close]
BLAST of Caspase-3B vs. Ensembl Cavefish
Match: casp7 (caspase 7 [Source:NCBI gene;Acc:103041716])

HSP 1 Score: 199.134 bits (505), Expect = 1.884e-61
Identity = 103/244 (42.21%), Postives = 145/244 (59.43%), Query Frame = 2 
Query:  101 YDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSSNIE-------KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            Y MS +++  C+IINN+ F  +  +  R GT+ D   L   F  L +    Y + T   M  +L+ +S+ +D  + S    I+LSHG +G+IYG DG + +  +   F+GD C+ L+GKPK+FFIQACRG ++D G+  D G  +  IE       KIP+EADFL  YSTVPGY+SWRN G GSW++Q+LC  L ++ K  +++QIL +VN  VATNF S +         QI   V ML K L
Sbjct:   98 YKMSHRRVGKCIIINNKNFDEKTGMNVRNGTDRDAGELFKCFKNLGFDVFVYNDQTCAKMERLLKEVSE-EDHSDSSCFACILLSHGEEGMIYGTDGAMPIKSMTSLFRGDMCKSLVGKPKLFFIQACRGSEFDDGIQTDSGPPNDTIETDANPRHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLNEFGKQLEIMQILTRVNYMVATNFESWSEDPRFSEKKQIPCVVSMLTKEL 340
[Close]
BLAST of Caspase-3B vs. Ensembl Cavefish
Match: casp3b (caspase-3 [Source:NCBI gene;Acc:103025383])

HSP 1 Score: 194.512 bits (493), Expect = 2.049e-60
Identity = 97/227 (42.73%), Postives = 134/227 (59.03%), Query Frame = 2 
Query:  125 CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSN-IEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            C+IINN  F     +  R GT+ D   +  VF++L +      N T   M  IL   S ++D    +  V ++LSHG +G I+G DG ++L  L   F+G++C  L GKPK+FFIQACRG + D G+  D V  S    KIP+EADFL  YST PGY+SWRN   GSW+I SLC+ L KY +  +++QI+ +VN+ VA  F S +N+   + M QI   + ML K L
Sbjct:   58 CIIINNRNFDRSTGMSDRAGTDVDAGKMLKVFSELGFKASVQNNRTVSQMRQILTSAS-KEDHSKSAMFVCVMLSHGDEGTIFGTDGCMELKELTRLFRGNQCPSLAGKPKLFFIQACRGSELDPGIETDSVDDSEGTHKIPVEADFLYVYSTAPGYYSWRNTANGSWFISSLCEMLAKYGRELEIMQIMTRVNHKVALEFESSSNTPGFNAMKQIPCIMSMLTKEL 283
[Close]
BLAST of Caspase-3B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005841.1 (pep scaffold:Pmarinus_7.0:GL476535:290070:293064:-1 gene:ENSPMAG00000005266.1 transcript:ENSPMAT00000005841.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 185.267 bits (469), Expect = 5.949e-58
Identity = 101/247 (40.89%), Postives = 138/247 (55.87%), Query Frame = 2 
Query:   89 SSKSYDMSKQ--KLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGV-------LADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            +S  Y+M  Q    C+IINNE F PQ  +  RKGT+ D   L+  F  L +  +SY ++T   M   L++ S  +D    +  V  ILSHG +G++YG DG + +  L   F    C  L GKPK+FFIQACRG  +D+GV        +D   S    K P+E DFL  +STVPGY+SWRN   GSW+IQSLC+EL +     +LV+ILV VN  VAT + S +   + +   QI   + ML +  
Sbjct:    2 ASAQYNMHFQAKSKCIIINNENFSPQTGMNRRKGTDRDAMQLQVCFLSLGFQVESYKDLTCKQMVENLKKASS-EDHGTRACFVCAILSHGEEGVLYGTDGTLPVSILADIFSEKHCPSLAGKPKLFFIQACRGSMFDEGVDQVDGLRRSDDTDSRGYSKPPVEPDFLYAFSTVPGYYSWRNEEKGSWFIQSLCEELLRNSSQLELVKILVCVNRRVATQYVSCSRDITYNDKKQIPCIMSMLTREF 247
[Close]
BLAST of Caspase-3B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005440.1 (pep scaffold:Pmarinus_7.0:GL480504:970:21443:-1 gene:ENSPMAG00000004940.1 transcript:ENSPMAT00000005440.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 179.874 bits (455), Expect = 8.823e-56
Identity = 97/250 (38.80%), Postives = 143/250 (57.20%), Query Frame = 2 
Query:   98 SYDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKG---VLADG---VHSSNIEKIP----IEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQIV 811
            SY M  + +  C+IINNE F P+  +  R GT+ D + L   F+ L +      ++T   M   L+ +SQ ++L N + +V ++LSHG DG++YG DGP+ L  +   F    C  L+GKP++ FIQACRG   DKG   V  DG   V  +++  +P    ++ DFL  ++TV GYFSWRN   GS +IQ LC EL+++ +  +L +IL +VN  VAT F S+T     +   QI   V ML K L ++
Sbjct:    2 SYSMHYKSIGNCIIINNENFFPRAGMAKRNGTQMDVSRLSECFDSLGFDVKYRKDLTCEEMRTFLKEVSQ-ENLKNCACLVCVVLSHGEDGVVYGTDGPLPLSDIVKPFADSSCPSLVGKPRLVFIQACRGTLLDKGVDKVECDGDPDVKEASL--LPTVDLMQPDFLFAFATVSGYFSWRNPANGSCFIQLLCSELQEHGQRMELTKILTRVNRRVATEFTSNTTDADLNNSKQIPCTVSMLTKELYLL 248
[Close]
BLAST of Caspase-3B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005498.1 (pep scaffold:Pmarinus_7.0:GL481204:7525:20312:1 gene:ENSPMAG00000004980.1 transcript:ENSPMAT00000005498.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 126.331 bits (316), Expect = 4.011e-33
Identity = 83/223 (37.22%), Postives = 113/223 (50.67%), Query Frame = 2 
Query:  122 LCVIINNEEFHPQLNLQP----RKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGP-VQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGV--------LADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELE-KYYKTHDLVQILVKVNNTVATNFRSHTNSFS 748
            +C+IINNEEF       P    R+GT  D   L+ VF  L +    + N+T   M   L   S + +  N    V  IL+HG    ++G DG  + +  +  YF G  C+ L+GKPK+FFIQAC+G +              ADG  S     IP EAD L+G +TV GY S+R+   GSWYIQ+LC  LE K    +D++ IL  VN  VA       N ++
Sbjct:  277 ICLIINNEEFSSDFKTSPKLKKREGTHIDAEKLEKVFKYLGFKILLHNNLTVGQMIETLMSCS-KMNHKNHDVFVCCILTHGEINCVFGSDGKSLLITEVTSYFNGSACKSLLGKPKLFFIQACQGHEKQSECHLAADADIDADGPVSPISYSIPDEADILLGMATVSGYLSFRHRREGSWYIQTLCNLLEQKCNGQNDILAILTDVNRVVAEKTARMKNPYT 498
[Close]
BLAST of Caspase-3B vs. Ensembl Sea Lamprey
Match: casp3a (caspase 3, apoptosis-related cysteine peptidase a [Source:ZFIN;Acc:ZDB-GENE-011210-1])

HSP 1 Score: 96.2857 bits (238), Expect = 4.276e-25
Identity = 51/126 (40.48%), Postives = 77/126 (61.11%), Query Frame = 2 
Query:  467 IQACRGQKYDKG--VLADG---VHSSNIEK--IPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTH-DLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQIV*PK 820
            +QACRG ++D+G  + AD      S +I +  IP+EADFL  YSTVPGY+SWRN   GSW++Q+ C+ L++   ++ +L+Q+L +VN  VA ++ S ++     G  QI   V ML K      P+
Sbjct:    1 LQACRGTEFDEGSTMCADNDVETDSESISRQTIPVEADFLYCYSTVPGYYSWRNVATGSWFVQAFCKVLKESANSNLELMQLLTRVNRKVAYDYVSFSSDTRFSGKKQIPCIVSMLTKEFHFPSPR 126
[Close]
BLAST of Caspase-3B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008527.1 (pep scaffold:Pmarinus_7.0:GL477443:35181:37755:1 gene:ENSPMAG00000007721.1 transcript:ENSPMAT00000008527.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.1225 bits (222), Expect = 1.191e-22
Identity = 46/131 (35.11%), Postives = 75/131 (57.25%), Query Frame = 2 
Query:   92 SKSYDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQAC 478
            S +Y+M+   +  CVIINN+ F     +  R GT+ D + L+ +F  + +  +   N+    M + +  ++++ D    +  V I+LSHG +G+IYG D  + +  L   F+GD CR L+GKPK+FFIQ C
Sbjct:   11 SVAYNMNYSNVGYCVIINNKTFDQSTGMGERTGTDVDRDMLEKLFKDIGFKVEVKNNMKRKEMVSYITEVAEK-DHRQCACFVCILLSHGDEGVIYGTDNYLPIRDLTTPFRGDLCRSLVGKPKLFFIQVC 140
[Close]
BLAST of Caspase-3B vs. Ensembl Nematostella
Match: EDO41832 (Caspase [Source:UniProtKB/TrEMBL;Acc:A7S364])

HSP 1 Score: 181.415 bits (459), Expect = 1.753e-54
Identity = 93/237 (39.24%), Postives = 144/237 (60.76%), Query Frame = 2 
Query:  104 DMSKQKLCVIINNEEFHPQLNLQ--PRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD--GVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            D + + + VIINN++F P   +   PR GT  D + L+  F  L +  + + N T++    I++ L QR    N +A++  IL+HG +GI+Y  DG +++  +   FKGD    L+GKPK+F  QAC+G +Y  G  A   G   +N  ++P+EADFL  YSTVPGY+SWRN   GSW+IQS+C+   K+    D+++++ +VN+ V+T ++S T  + +D   Q+ S V MLRK L
Sbjct:  151 DKTPRGVAVIINNKDFLPASGMHRYPRNGTNVDRDSLEKTFKALQFDVEVHNNKTTYETNRIIKELGQRS-YSNYNAMIFAILTHGEEGILYTTDGTIEIRSMMKAFKGDN---LVGKPKIFIFQACQGHEYMDGKDATDAGPEDANRVQVPVEADFLYAYSTVPGYYSWRNSVNGSWFIQSICEVFNKHMHNMDVLRMMTRVNSLVST-YQSRTGDYYSDRKKQVPSIVSMLRKDL 382
[Close]
BLAST of Caspase-3B vs. Ensembl Nematostella
Match: EDO41263 (Caspase [Source:UniProtKB/TrEMBL;Acc:A7S4V9])

HSP 1 Score: 160.229 bits (404), Expect = 1.015e-46
Identity = 91/228 (39.91%), Postives = 130/228 (57.02%), Query Frame = 2 
Query:  125 CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPV-QLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHS-SNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            C+IINN  F     L+ R G++ D + L+S+F  L Y      ++T   M N L   + + +  N  ++VV ILSHG +G IYGVDG +  +  +   F G + + LIGKPK+FF+QACRG  +D G   + + S ++   +P EADFLI Y+TVPGY SWR+   GSW+IQ+L +  +    T D++ +L+KVN  VA  F S           Q+ S V ML K L
Sbjct:  129 CLIINNVRFDADSGLKSRAGSDIDASNLQSLFMSLRYRVKRLNDLTMRQMKNTLFDFA-KNNHKNSDSVVVCILSHGLEGRIYGVDGGLLNISDVISMFNGYQAKDLIGKPKLFFLQACRGGDFDHGARMEQIDSPTDKSSLPSEADFLIAYATVPGYVSWRHQEKGSWFIQALVEVFKTDATTEDVLSMLIKVNRKVALEFESFNRK------KQMPSPVVMLTKKL 349
[Close]
BLAST of Caspase-3B vs. Ensembl Nematostella
Match: EDO34460 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPA7])

HSP 1 Score: 156.377 bits (394), Expect = 1.471e-46
Identity = 91/244 (37.30%), Postives = 132/244 (54.10%), Query Frame = 2 
Query:   98 SYDMSKQK--LCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGP-VQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKI------PIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            +Y M+ +   +C+II+N+ F  +  L+ R G E D   LK  F  L++  +   + T+  MY I +  S   D       V  ILSHG  G IYG D   ++++ +   FKG+ C  L  KPK+FFIQACRGQ +D+G+ AD     +          P E+ FL+GY+T PGY SWR+   GSWYI  LC+ L  Y + +DLV ++VKVN+ V       + +F+  G  Q  + V  LRK +
Sbjct:    3 AYPMTSRPRGICLIISNQHFD-KPELRKRDGNEQDVENLKRTFENLHFVVEIRQDKTASEMYTIAREFSS-IDHSAYDLFVCCILSHGMLGSIYGSDSNLIEINEISSQFKGNACPTLAHKPKLFFIQACRGQDFDRGIQADATRDMDASDAVRQNAEPNESHFLLGYATPPGYVSWRSQVHGSWYISFLCEVLSTYCERYDLVTMMVKVNDKV-------SEAFTRKGYKQCPAPVVTLRKRI 237
[Close]
BLAST of Caspase-3B vs. Ensembl Nematostella
Match: EDO31855 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S119])

HSP 1 Score: 135.961 bits (341), Expect = 7.887e-39
Identity = 85/233 (36.48%), Postives = 129/233 (55.36%), Query Frame = 2 
Query:  113 KQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVD-GPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEK--IPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            K+   +IINN+EF  + +++ RKG+  D   L  +F+    T  +  N TS  M  +L+  S++ D       + IILSHGS   IYGVD   VQ++ L   F+G  C  L GKPKVFF+QACRG K +   +        I    +P ++DFLI Y++ PGY S+RN  +GSW+I+S+      + +T  L+ ++++VN+ VA+         S  G  Q+ S VCML + +
Sbjct:    1 KKGYVLIINNQEFPSRSDVE-RKGSAEDVKQLYQLFDDFGMTVKTIQNKTSLEMLELLEETSEK-DFTKFDCFICIILSHGSHSGIYGVDEKAVQVESLTNKFRGSTCPSLQGKPKVFFLQACRGAKKELVAVESDSEPVPIRHSGLPSDSDFLICYASSPGYESYRNPELGSWFIRSIVDVFRNFGETEHLMDLMLRVNHRVAS-------LNSNLGHKQMPSEVCMLTRKV 224
[Close]
BLAST of Caspase-3B vs. Ensembl Nematostella
Match: EDO42564 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S119])

HSP 1 Score: 135.961 bits (341), Expect = 7.887e-39
Identity = 85/233 (36.48%), Postives = 129/233 (55.36%), Query Frame = 2 
Query:  113 KQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVD-GPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEK--IPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            K+   +IINN+EF  + +++ RKG+  D   L  +F+    T  +  N TS  M  +L+  S++ D       + IILSHGS   IYGVD   VQ++ L   F+G  C  L GKPKVFF+QACRG K +   +        I    +P ++DFLI Y++ PGY S+RN  +GSW+I+S+      + +T  L+ ++++VN+ VA+         S  G  Q+ S VCML + +
Sbjct:    1 KKGYVLIINNQEFPSRSDVE-RKGSAEDVKQLYQLFDDFGMTVKTIQNKTSLEMLELLEETSEK-DFTKFDCFICIILSHGSHSGIYGVDEKAVQVESLTNKFRGSTCPSLQGKPKVFFLQACRGAKKELVAVESDSEPVPIRHSGLPSDSDFLICYASSPGYESYRNPELGSWFIRSIVDVFRNFGETEHLMDLMLRVNHRVAS-------LNSNLGHKQMPSEVCMLTRKV 224
[Close]
BLAST of Caspase-3B vs. Ensembl Medaka
Match: casp3 (caspase 3 [Source:NCBI gene;Acc:100049215])

HSP 1 Score: 219.935 bits (559), Expect = 2.977e-70
Identity = 109/235 (46.38%), Postives = 146/235 (62.13%), Query Frame = 2 
Query:   98 SYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            S D  K  +C+IINN+ FH    + PR GT+ND       F KL Y    Y + T   M  + +++S  QD    ++   +ILSHG +G+IYG DGPV  ++L    KG  C  L+GKPK+FFIQACRG  +D+G+  D    ++ EKIP+EADFL  YSTV GY+SWR+   GSW+IQSLC+ LEK+ KT DL+QI+ +VN+ VAT+F S +N+    G  QI   V ML K  
Sbjct:   49 SMDYPKMGICLIINNKNFHKDSGMGPRNGTDNDAAAAWKSFMKLGYEIQMYNDQTVDQMKKLFRQMSN-QDHSKFASFACVILSHGEEGVIYGTDGPVSFNKLIECLKGRSCLSLVGKPKLFFIQACRGTLFDEGIEHDAKDDTS-EKIPLEADFLFAYSTVSGYYSWRSTANGSWFIQSLCEMLEKFSKTLDLMQIMTRVNHKVATHFESSSNAPGFSGKKQIPCIVSMLTKDF 281
[Close]
BLAST of Caspase-3B vs. Ensembl Medaka
Match: casp3 (caspase 3 [Source:NCBI gene;Acc:100049215])

HSP 1 Score: 219.935 bits (559), Expect = 3.451e-70
Identity = 109/235 (46.38%), Postives = 146/235 (62.13%), Query Frame = 2 
Query:   98 SYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            S D  K  +C+IINN+ FH    + PR GT+ND       F KL Y    Y + T   M  + +++S  QD    ++   +ILSHG +G+IYG DGPV  ++L    KG  C  L+GKPK+FFIQACRG  +D+G+  D    ++ EKIP+EADFL  YSTV GY+SWR+   GSW+IQSLC+ LEK+ KT DL+QI+ +VN+ VAT+F S +N+    G  QI   V ML K  
Sbjct:   51 SMDYPKMGICLIINNKNFHKDSGMGPRNGTDNDAAAAWKSFMKLGYEIQMYNDQTVDQMKKLFRQMSN-QDHSKFASFACVILSHGEEGVIYGTDGPVSFNKLIECLKGRSCLSLVGKPKLFFIQACRGTLFDEGIEHDAKDDTS-EKIPLEADFLFAYSTVSGYYSWRSTANGSWFIQSLCEMLEKFSKTLDLMQIMTRVNHKVATHFESSSNAPGFSGKKQIPCIVSMLTKDF 283
[Close]
BLAST of Caspase-3B vs. Ensembl Medaka
Match: casp7 (caspase 7 [Source:NCBI gene;Acc:101161677])

HSP 1 Score: 204.142 bits (518), Expect = 3.992e-64
Identity = 107/248 (43.15%), Postives = 147/248 (59.27%), Query Frame = 2 
Query:   89 SSKSYDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSSNIE-------KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            S+  Y MS Q++  C+IINN+ F     +  R GT+ D   L   F  L +    Y + T   M ++L+  SQ +D  + S    I+LSHG +G+IYG DG + +  +   F+GDKC+ L+GKPK+FFIQACRG ++D+GV  D G  +  IE       KIP+EADFL  YSTVPGY+SWRN G GSW++Q+LC  L ++ K  +++QIL +VN  VA NF S +         QI   V ML K L
Sbjct:   36 STFQYKMSHQRVGKCIIINNKNFDDNTGMNVRNGTDRDAGELYKCFKSLGFDVSIYNDQTCDKMEHLLKEASQ-EDHSDSSCFACILLSHGEEGMIYGTDGAIPIKTMTSLFRGDKCKSLVGKPKLFFIQACRGSEFDEGVQTDSGPPNDTIETDANPSHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLNEFGKQLEIMQILTRVNYMVANNFESWSEDPRYSEKKQIPCVVSMLTKEL 282
[Close]
BLAST of Caspase-3B vs. Ensembl Medaka
Match: casp7 (caspase 7 [Source:NCBI gene;Acc:101161677])

HSP 1 Score: 204.527 bits (519), Expect = 5.917e-64
Identity = 107/248 (43.15%), Postives = 147/248 (59.27%), Query Frame = 2 
Query:   89 SSKSYDMSKQKL--CVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLAD-GVHSSNIE-------KIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            S+  Y MS Q++  C+IINN+ F     +  R GT+ D   L   F  L +    Y + T   M ++L+  SQ +D  + S    I+LSHG +G+IYG DG + +  +   F+GDKC+ L+GKPK+FFIQACRG ++D+GV  D G  +  IE       KIP+EADFL  YSTVPGY+SWRN G GSW++Q+LC  L ++ K  +++QIL +VN  VA NF S +         QI   V ML K L
Sbjct:   65 STFQYKMSHQRVGKCIIINNKNFDDNTGMNVRNGTDRDAGELYKCFKSLGFDVSIYNDQTCDKMEHLLKEASQ-EDHSDSSCFACILLSHGEEGMIYGTDGAIPIKTMTSLFRGDKCKSLVGKPKLFFIQACRGSEFDEGVQTDSGPPNDTIETDANPSHKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQALCNVLNEFGKQLEIMQILTRVNYMVANNFESWSEDPRYSEKKQIPCVVSMLTKEL 311
[Close]
BLAST of Caspase-3B vs. Ensembl Medaka
Match: casp3a (caspase 3B [Source:NCBI gene;Acc:100049265])

HSP 1 Score: 194.126 bits (492), Expect = 1.411e-60
Identity = 104/251 (41.43%), Postives = 143/251 (56.97%), Query Frame = 2 
Query:   62 DFMDIVDGGSSKSYDMSKQ----KLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSL 802
            D MD+    SS S+  S       LC+IINN+ F     +  R GT+ D      VF+KL Y    Y + T   +  +L  +S R D  + ++ V I+LSHG +G+ +G DG ++L  L   F+GD C+ L+GKPK+FFIQACRG + D G+ AD     +  KIP+EADFL  +ST PGY+SWRN   GSW+I SLC+ L KY K  +L+ I+ +VN+ VA  F S +         QI   V ML K +
Sbjct:   14 DRMDVDGKPSSHSFRYSLNFPTIGLCIIINNKNFDRGTGMNQRNGTDIDAASAMKVFSKLGYRVKIYNDQTVKQIKQLLTDVS-RMDHSDSASFVCILLSHGDEGVFFGTDGSIELKTLTSLFRGDHCKSLVGKPKLFFIQACRGTELDDGIEADS--KEDTTKIPVEADFLYAFSTAPGYYSWRNTMTGSWFINSLCEMLSKYGKELELLHIMTRVNHMVAVEFESISTLPGFHAKKQIPCIVSMLTKEM 261
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BLAST of Caspase-3B vs. Planmine SMEST
Match: SMESG000053164.1 (SMESG000053164.1)

HSP 1 Score: 380.563 bits (976), Expect = 5.109e-135
Identity = 185/195 (94.87%), Postives = 189/195 (96.92%), Query Frame = 2 
Query:   14 MEESCDISINTGVLDGDFMDIVDGGSSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFS 598
            M+ESCDISINTGVLDGDFMD VDGGSSK+YDMSKQKLCVIINNEEFHPQLNL PRKGTENDFNYLKSVFNKLNYTTDSYTNV SHNM NILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVL DGVHSSNIEKIPIEADFLIGYSTVPG ++
Sbjct:    1 MDESCDISINTGVLDGDFMDNVDGGSSKAYDMSKQKLCVIINNEEFHPQLNLPPRKGTENDFNYLKSVFNKLNYTTDSYTNVISHNMNNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLTDGVHSSNIEKIPIEADFLIGYSTVPGMYN 195
[Close]
BLAST of Caspase-3B vs. Planmine SMEST
Match: SMESG000053166.1 (SMESG000053166.1)

HSP 1 Score: 330.487 bits (846), Expect = 3.864e-114
Identity = 159/252 (63.10%), Postives = 194/252 (76.98%), Query Frame = 2 
Query:   53 LDGDFMDIVDGGSSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQI 808
            ++ D  D+VDG  S+ Y++SK KLC IINNEEF P LN+  R GT  DF  LK VF KL +  ++Y N  S  + + L++LSQR++L ++S +VVIILSHG++G IYG DGPV LDR+FGYFKGDKCRGL+GKPKVF IQACRG KYD GV+AD   S++IEKIPIEADFLIGYSTV GYFSWRNG  GSWYIQSLC ELE   K+ +L+QIL+ VNNTVA  ++SH+    +DG VQI SFVCMLRKSL +
Sbjct:   11 INEDNFDMVDGKESEIYEISKIKLCFIINNEEFQPNLNMAARNGTGVDFKRLKQVFTKLGFKVENYKNFKSSEICSNLKQLSQRKELKDISLLVVIILSHGTEGTIYGTDGPVDLDRIFGYFKGDKCRGLLGKPKVFLIQACRGDKYDHGVIADDFLSNSIEKIPIEADFLIGYSTVAGYFSWRNGKNGSWYIQSLCDELENLSKSCELLQILINVNNTVAEKYQSHSKKEKSDGKVQIPSFVCMLRKSLWL 262
[Close]
BLAST of Caspase-3B vs. Planmine SMEST
Match: SMESG000053168.1 (SMESG000053168.1)

HSP 1 Score: 303.138 bits (775), Expect = 1.597e-103
Identity = 140/248 (56.45%), Postives = 183/248 (73.79%), Query Frame = 2 
Query:   68 MDIVDGGSSKSYDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQIV 811
            MD VD   +  Y +++ KLC IINNEEF P+LNL  R GT+ DF  LK++F KL +T +++ N T+  M   L+ +SQR++L + S  V  ILSHG +GIIYG D  +Q+DRL GYFKGDKC+GL+GKPK+FFIQACRG ++DKG+ AD   S+NIEKIPIEAD L+GYSTVPGYFSWRN   GSWY+Q+LC E EK  K+ D+V +LV+VN  VA+NF+S+T    + G +QI SF CMLRK + ++
Sbjct:    1 MDSVDSKENNDYFINENKLCYIINNEEFDPKLNLSVRSGTQRDFEKLKALFRKLGFTVENHKNCTADMMLKNLEEISQRKNLKDYSMFVCFILSHGDEGIIYGRDHFIQIDRLLGYFKGDKCKGLVGKPKLFFIQACRGDRFDKGIFADAGDSNNIEKIPIEADVLVGYSTVPGYFSWRNSSNGSWYVQALCNEFEKNAKSDDVVSLLVRVNANVASNFKSNTGEKQSHGKLQIPSFTCMLRKRVWLI 248
[Close]
BLAST of Caspase-3B vs. Planmine SMEST
Match: SMESG000016936.1 (SMESG000016936.1)

HSP 1 Score: 224.557 bits (571), Expect = 1.061e-72
Identity = 114/236 (48.31%), Postives = 150/236 (63.56%), Query Frame = 2 
Query:  101 YDMSKQKLCVIINNEEFHPQLNLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQI 808
            Y+ S +K C IINNE F  +L L  RKGT  DF  L     K  +      N  S  M   L+++S R DL   S  + IILSHGSD IIYG +  +++ RL   FK ++C+ L GKPKVF IQAC+G K D GVLAD ++S+NI  +P+E +FLIGYSTV  Y SWRN  +GSWYI S C+ + KY    DL+ +LV+VNN V++ F+S +   +T+  VQISSFVCML K + +
Sbjct:   13 YERSGKKFCYIINNEVFDAKLRLSKRKGTNKDFQNLFDTLTKFEFEIYWANNCRSLEMLQNLKKISLRPDLGEYSIFLCIILSHGSDEIIYGFEDFIEIRRLLHPFKENECKALQGKPKVFIIQACKGNKCDPGVLADDLYSNNIAAVPMELNFLIGYSTVSDYLSWRNEVVGSWYIHSFCEIVRKYGDKEDLLHLLVRVNNNVSSKFKSKSMYTATNDKVQISSFVCMLVKDVYL 248
[Close]
BLAST of Caspase-3B vs. Planmine SMEST
Match: SMESG000016936.1 (SMESG000016936.1)

HSP 1 Score: 189.119 bits (479), Expect = 8.177e-60
Identity = 92/179 (51.40%), Postives = 124/179 (69.27%), Query Frame = 2 
Query:  272 MYNILQRLSQRQDLVNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVFFIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGGIGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMVQISSFVCMLRKSLQI 808
            M   L+++S R DL   S  + IILSHGSD IIYG +  +++ RL   FK ++C+ L GKPKVF IQAC+G K D GVLAD ++S+NI  +P+E +FLIGYSTV  Y SWRN  +GSWYI S C+ + KY    DL+ +LV+VNN V++ F+S +   +T+  VQISSFVCML K + +
Sbjct:    1 MLQNLKKISLRPDLGEYSIFLCIILSHGSDEIIYGFEDFIEIRRLLHPFKENECKALQGKPKVFIIQACKGNKCDPGVLADDLYSNNIAAVPMELNFLIGYSTVSDYLSWRNEVVGSWYIHSFCEIVRKYGDKEDLLHLLVRVNNNVSSKFKSKSMYTATNDKVQISSFVCMLVKDVYL 179
The following BLAST results are available for this feature:
BLAST of Caspase-3B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CASP36.908e-6342.55caspase 3 [Source:HGNC Symbol;Acc:HGNC:1504][more]
CASP36.908e-6342.55caspase 3 [Source:HGNC Symbol;Acc:HGNC:1504][more]
CASP79.477e-6040.66caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508][more]
CASP71.457e-5940.66caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508][more]
CASP71.457e-5940.66caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508][more]
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BLAST of Caspase-3B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ced-36.283e-3430.16Cell death protein 3 Cell death protein 3 subunit ... [more]
ced-31.381e-3230.16Cell death protein 3 Cell death protein 3 subunit ... [more]
csp-15.622e-2529.86Caspase A Caspase A subunit p16 Caspase A subunit ... [more]
csp-19.880e-2429.86Caspase A Caspase A subunit p16 Caspase A subunit ... [more]
csp-21.092e-2228.64Putative inactive caspase B Putative inactive casp... [more]
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BLAST of Caspase-3B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dcp-19.292e-4638.96gene:FBgn0010501 transcript:FBtr0072062[more]
Drice3.691e-4237.71gene:FBgn0019972 transcript:FBtr0085482[more]
Decay3.359e-3429.62gene:FBgn0028381 transcript:FBtr0083304[more]
Dronc3.764e-2328.90gene:FBgn0026404 transcript:FBtr0076347[more]
Damm2.437e-1730.69gene:FBgn0033659 transcript:FBtr0088061[more]
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BLAST of Caspase-3B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
casp3b1.936e-6844.25caspase 3, apoptosis-related cysteine peptidase b ... [more]
casp75.425e-6343.44caspase 7, apoptosis-related cysteine peptidase [S... [more]
casp3a4.058e-6242.61caspase 3, apoptosis-related cysteine peptidase a ... [more]
casp3a4.058e-6242.61caspase 3, apoptosis-related cysteine peptidase a ... [more]
casp6b.21.039e-4435.83caspase 6b.2, apoptosis-related cysteine peptidase... [more]
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BLAST of Caspase-3B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
casp3.22.671e-6342.98caspase 3, gene 2 [Source:NCBI gene;Acc:100151728][more]
ENSXETT00000003846.14.627e-5237.93caspase 3, gene 1 [Source:NCBI gene;Acc:100486222][more]
lrrc381.501e-4939.32leucine rich repeat containing 38 [Source:Xenbase;... [more]
calb22.355e-4434.70calbindin 2 [Source:Xenbase;Acc:XB-GENE-960001][more]
bmt24.739e-3434.24base methyltransferase of 25S rRNA 2 homolog [Sour... [more]
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BLAST of Caspase-3B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Casp31.754e-6341.94caspase 3 [Source:MGI Symbol;Acc:MGI:107739][more]
Casp31.754e-6341.94caspase 3 [Source:MGI Symbol;Acc:MGI:107739][more]
Casp75.128e-6040.25caspase 7 [Source:MGI Symbol;Acc:MGI:109383][more]
Casp71.454e-4341.44caspase 7 [Source:MGI Symbol;Acc:MGI:109383][more]
Casp61.245e-4029.92caspase 6 [Source:MGI Symbol;Acc:MGI:1312921][more]
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BLAST of Caspase-3B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8MJU1|CASP3_FELCA8.938e-6544.26Caspase-3 OS=Felis catus OX=9685 GN=CASP3 PE=2 SV=... [more]
sp|Q60431|CASP3_MESAU9.853e-6542.92Caspase-3 OS=Mesocricetus auratus OX=10036 GN=CASP... [more]
sp|Q8MKI5|CASP3_CANLF4.994e-6443.04Caspase-3 OS=Canis lupus familiaris OX=9615 GN=CAS... [more]
sp|P70677|CASP3_MOUSE1.227e-6241.94Caspase-3 OS=Mus musculus OX=10090 GN=Casp3 PE=1 S... [more]
sp|P55213|CASP3_RAT3.075e-6242.08Caspase-3 OS=Rattus norvegicus OX=10116 GN=Casp3 P... [more]
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BLAST of Caspase-3B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Y6I1H46.385e-12168.40Caspase-3B OS=Dugesia japonica OX=6161 GN=cas-3B P... [more]
A0A4Y6I1I12.839e-11062.10Caspase-3A OS=Dugesia japonica OX=6161 GN=cas-3A P... [more]
A0A493QY723.338e-10358.87Caspase-7 OS=Dugesia japonica OX=6161 GN=CASP-7 PE... [more]
A0A4Y6I1G15.198e-10057.26Caspase-7 OS=Dugesia japonica OX=6161 GN=cas-7 PE=... [more]
A0A4Y6I0S17.095e-7046.94Caspase-3C OS=Dugesia japonica OX=6161 GN=cas-3C P... [more]
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BLAST of Caspase-3B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000034295.12.576e-6341.59pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000039856.14.252e-6341.59pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
casp71.884e-6142.21caspase 7 [Source:NCBI gene;Acc:103041716][more]
casp71.884e-6142.21caspase 7 [Source:NCBI gene;Acc:103041716][more]
casp3b2.049e-6042.73caspase-3 [Source:NCBI gene;Acc:103025383][more]
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BLAST of Caspase-3B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000005841.15.949e-5840.89pep scaffold:Pmarinus_7.0:GL476535:290070:293064:-... [more]
ENSPMAT00000005440.18.823e-5638.80pep scaffold:Pmarinus_7.0:GL480504:970:21443:-1 ge... [more]
ENSPMAT00000005498.14.011e-3337.22pep scaffold:Pmarinus_7.0:GL481204:7525:20312:1 ge... [more]
casp3a4.276e-2540.48caspase 3, apoptosis-related cysteine peptidase a ... [more]
ENSPMAT00000008527.11.191e-2235.11pep scaffold:Pmarinus_7.0:GL477443:35181:37755:1 g... [more]
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BLAST of Caspase-3B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Caspase-3B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO418321.753e-5439.24Caspase [Source:UniProtKB/TrEMBL;Acc:A7S364][more]
EDO412631.015e-4639.91Caspase [Source:UniProtKB/TrEMBL;Acc:A7S4V9][more]
EDO344601.471e-4637.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO318557.887e-3936.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO425647.887e-3936.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Caspase-3B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
casp32.977e-7046.38caspase 3 [Source:NCBI gene;Acc:100049215][more]
casp33.451e-7046.38caspase 3 [Source:NCBI gene;Acc:100049215][more]
casp73.992e-6443.15caspase 7 [Source:NCBI gene;Acc:101161677][more]
casp75.917e-6443.15caspase 7 [Source:NCBI gene;Acc:101161677][more]
casp3a1.411e-6041.43caspase 3B [Source:NCBI gene;Acc:100049265][more]
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BLAST of Caspase-3B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053164.15.109e-13594.87SMESG000053164.1[more]
SMESG000053166.13.864e-11463.10SMESG000053166.1[more]
SMESG000053168.11.597e-10356.45SMESG000053168.1[more]
SMESG000016936.11.061e-7248.31SMESG000016936.1[more]
SMESG000016936.18.177e-6051.40SMESG000016936.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005973 ID=SMED30005973|Name=Caspase-3B|organism=Schmidtea mediterranea sexual|type=transcript|length=894bp
CTAATATAAAAAAATGGAGGAAAGTTGTGATATATCTATCAATACTGGCG
TATTAGATGGAGATTTTATGGATATTGTTGATGGCGGATCTTCCAAATCA
TATGATATGAGTAAACAAAAATTGTGCGTTATAATAAACAATGAAGAATT
TCATCCTCAACTAAACTTGCAACCTCGAAAAGGAACTGAAAATGATTTTA
ATTATTTGAAATCAGTTTTTAATAAACTTAACTATACCACCGATTCATAC
ACAAATGTTACTTCTCACAACATGTACAATATTCTTCAAAGACTGTCACA
GAGACAAGATTTGGTCAACGTGAGTGCTATCGTGGTAATAATTCTTTCGC
ATGGATCTGATGGAATAATTTATGGTGTTGATGGACCTGTCCAATTAGAT
CGATTATTTGGATATTTCAAAGGAGATAAGTGTAGAGGACTGATTGGTAA
ACCAAAGGTTTTCTTTATACAGGCTTGTCGAGGACAAAAATATGATAAAG
GTGTTCTTGCTGATGGGGTTCATTCTTCTAATATTGAAAAAATTCCAATT
GAAGCAGACTTTTTAATTGGATATTCAACTGTACCGGGGTACTTTTCTTG
GAGAAATGGTGGCATTGGTAGCTGGTACATCCAGTCATTATGTCAAGAAT
TAGAGAAGTATTATAAAACACATGATCTGGTACAAATATTAGTAAAAGTC
AACAATACTGTTGCCACTAATTTTCGTTCCCATACAAATAGTTTTTCAAC
TGATGGAATGGTTCAAATTTCATCATTTGTTTGTATGCTTAGAAAATCTT
TACAGATTGTCTGACCAAAAGTTGCAGGTGATATCGGCTGAAGAATAATA
ACGGTCTAATTTTCATATCAATTAATCAAAATTTCTTATAAAAA
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protein sequence of SMED30005973-orf-1

>SMED30005973-orf-1 ID=SMED30005973-orf-1|Name=SMED30005973-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=267bp
MEESCDISINTGVLDGDFMDIVDGGSSKSYDMSKQKLCVIINNEEFHPQL
NLQPRKGTENDFNYLKSVFNKLNYTTDSYTNVTSHNMYNILQRLSQRQDL
VNVSAIVVIILSHGSDGIIYGVDGPVQLDRLFGYFKGDKCRGLIGKPKVF
FIQACRGQKYDKGVLADGVHSSNIEKIPIEADFLIGYSTVPGYFSWRNGG
IGSWYIQSLCQELEKYYKTHDLVQILVKVNNTVATNFRSHTNSFSTDGMV
QISSFVCMLRKSLQIV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000418head
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR002398Pept_C14
IPR015917Pept_C14A
IPR029030Caspase-like_dom_sf
IPR033139Caspase_cys_AS
IPR002138Pept_C14_p10
IPR001309Pept_C14_p20
Vocabulary: molecular function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0004197cysteine-type endopeptidase activity
GO:0008233peptidase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0006915apoptotic process
GO:0006508proteolysis
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015917Peptidase C14A, caspase catalytic domainPRINTSPR00376IL1BCENZYMEcoord: 55..73
score: 32.22
coord: 195..206
score: 58.08
coord: 140..158
score: 66.51
coord: 34..47
score: 40.04
coord: 106..114
score: 49.16
IPR015917Peptidase C14A, caspase catalytic domainSMARTSM00115caspase_2coord: 29..264
e-value: 5.3E-76
score: 268.5
IPR015917Peptidase C14A, caspase catalytic domainCDDcd00032CASccoord: 29..263
e-value: 1.40389E-84
score: 250.981
NoneNo IPR availablePFAMPF00656Peptidase_C14coord: 36..262
e-value: 6.7E-44
score: 150.7
NoneNo IPR availableGENE3DG3DSA:3.40.50.1460coord: 20..266
e-value: 3.2E-84
score: 283.7
NoneNo IPR availablePANTHERPTHR10454:SF198CASPASE-3coord: 32..262
IPR002398Peptidase C14 familyPANTHERPTHR10454CASPASEcoord: 32..262
IPR033139Peptidase family C14A, cysteine active sitePROSITEPS01122CASPASE_CYScoord: 146..157
IPR001309Peptidase C14, p20 domainPROSITEPS50208CASPASE_P20coord: 34..159
score: 42.945
IPR002138Peptidase C14, caspase non-catalytic subunit p10PROSITEPS50207CASPASE_P10coord: 173..266
score: 30.214
IPR029030Caspase-like domain superfamilySUPERFAMILYSSF52129Caspase-likecoord: 28..264