G-protein coupled receptor

Query:  438 CYCDDQCSLFGDCCHKHQQHHEPIASCH--------DGYYVIDKCLYKSTDGNLKDKCE----RKSEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEF-------ARVEKHKTSLKRKKDNTTEKSNYKYTFPKEFQRICHENVIITCDDDSEDALKLLCRNQPTFYVTENRGMVQKIYRNAYCFLCNTNSLQWSYKY------RLVVPTEIKA----LDFXXXXXXXXXXXXXXYQI-----------------NQTTFRNHSDSISCTENK--NFQFFEKV----------LTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVEN--PSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSENILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFIXXXXXXXXXXXXXXCFIYGMDVHKTTTKYIRSITENISSFATRKQSNA 2015
            C C   C  F DCC K     E +ASC            YVID+C    TD  ++ KCE       ++S +  L  VP  G   +  + ++N FCA C+      F        R+   + +++             ++        C   V+ +C D +   L   C    T  V +N G+    Y+N  C  CN  +              ++ P  I      LD N          L  Y++                  Q    N    I   ENK  N   FE++          LT+    +S+  LL ++L + C    RN   K  + L +S+L   +   +++   N    +  C+  ++  HF FLS F WM + A DV++S     + ++      +SR   FY L  + LP ++ + +  +  F +   + P++G+  C++    G LV F  P+ I L+ N  +  +  R +    + +  +  S    ++  +L +KL+++ G  W+  F+   F++ IL +I   L++ QGL + + F++   V +   K     T+    F T  +S+A
Sbjct:   48 CSCSPMCDFFDDCCDKESTQREEVASCRLRPTMPVRHFVYVIDRCPRDYTDDVIRGKCEDTKTGNDKLSTDGALPLVPVSG--ASSGMLYRNIFCAACHSVEDASFWVAEVPIRRLVAEEGAIRMAFQAALVAGRVTFSHLTFSAPFCRPRVVKSCPDSATKELASECVRGATSRVFQN-GIA---YKNIACASCNGANATSCVDPLPPLINHMIPPKRIMPYSLLLDLNTGSAALQTNRLGFYKVISLSDNSTNCSDLTYDPYQEKCSNLCSIIPSIENKVCNTSKFEEMVFKFDVGLGYLTLVGSALSIFGLLLLLLAYTCLPGLRNTPGKSLMSLAVSLL---LAQALYASGLNLMQPRSLCVSMAMFVHFFFLSQFCWMNVLAFDVWRSFRMHNIGLHSRLR-TRSRHFVFYCLYAWLLPAVVVLISFLLDLFQAS--IRPAYGQSFCWLGSRRGLLVLFASPISIMLIFNCGLFSLTARSLCIAGEDSDLLNLSRREHRRRLLLYVKLAVVMGLAWVFGFLATAFDSKILWYIFTALNTFQGLFICISFVFTQKVLRLLRK---KFTKGSGRFETSSRSHA 618          

Query:  528 YYVIDKCLYKSTDGNLKDKCERKSEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCN--GKNQFEFARVEKHKTSLKR-KKDNTTEKSNYKYTFPKEFQRICHENVIITCDDDSEDALKLLCRNQPTFY--VTENRGMVQKIYRNAYCFLCNTNSLQW--------------SYKYRLVVPTE---------IKALD---------FXXXXXXXXXXXXXXYQINQTTFRNHSDSISCTENKNFQFFEKVLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRL--RINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSENILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEK---KNFILCIKLSILFGATWLPAFVGVFFNNYILKFI 1871
            +Y++  CL      +++  CE           Y +P   + +   +T+KN +CA+CN    N   +  +E   + +   K  +      Y +  P    R   E+   TC + + + +   C+   TFY  +T  +      YRN YC +CN  +L                 Y+   ++P           ++  D         F +               NQT  + H          +F   +  LT+    +S+  L   V+VF    + R+ +SK TL L+I++L   +  ++ +  +  S   C   ++  H+ FLS+FFW ++ + D+++SIT+ +L  R N T A           +  +G P+++ + A  +      ++++P +G   C+I ++   + +F  P+ I L   I++      +I K   +  +      +++    +  L ++L+++ GATW   F+GVF ++ +   +
Sbjct:  120 FYMVTGCLPDWPIDDVRKACEESRNF--KETFYKIPVTSSTD---ITYKNGYCALCNYDLANTTFWNAIETPSSPITYFKLPDIIATQPYLHLRP--CSRRPQED---TCPEGTSENIVQKCK---TFYAPITTLKDEESPEYRNVYCAMCNGANLSALSCKPAEELSRFPVPYRQIAILPDPNLVTIFHPVLRTEDCYVKHRNRCFIKSPPELLRRQHDENSTNQTERKQH--------EMHFYTVQNYLTIVCVSLSICCLFLKVVVFSIYKEARSFSSKCTLCLSITLLMTQLLFLLVNSFKV-SAPVCTASAMLVHYGFLSTFFWTSVISFDIWRSITAAKLSSRRNSTLAFYS--------VTAWGAPMIIVVIAATVNWLAPTSLMSPLYGYSSCWIGRIWAQIAYFLAPMAILLAIGIVLYLNTVFYIRKTTDRARDFESKDGIQRSQHSHMTLFVRLALIMGATWGVGFLGVFVDSTVTDIL 579          

Query: 1146 FQFFEKVLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVEN--PSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSENILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEKKNFI---------LCIKLSILFGATWLPAFVGVFFNNYILKFI 1871
            F   +  LT+    +S+  L   V+VF    D R+ +SK TL L+I++L   +T ++F +V +   S+  C   ++  HF FLS+FFW ++ + D+++ IT+  L      +  + R L  Y +  +G P+++   A  +      ++++P +G   C+I  +   + +F  P+ + L+  +++      +I K        GH+ + E K+ +         L ++L+++ GATW   F+GVF ++ +   +
Sbjct:  356 FYTVQNYLTIVCVSLSICCLFLKVVVFSIYKDARSFSSKCTLCLSITLL---MTQLVFLLVNSFKVSRAVCTASAMLVHFGFLSTFFWTSVLSFDIWRGITAVNL------SSTRKRTLALYSVVAWGAPMIIVTVAAMVNWLAPTSLVSPLYGISSCWIGSIWAQITYFLAPMAVLLVIGVVLYLNTVFYIRKTT------GHARDFEFKDGVQQSQHSHMALYVRLALIMGATWGVGFLGVFVDSTVTDIL 593          

Query:  663 LTFKNAFCAVCNGKNQFEFARVEKHKTSLKRKKDNTTEKSNYKYTFPKEFQRIC--HENVIITCDDDSEDALKLLCRNQPTFYVTENRG-MVQKIYRNAYCFLCN-TNSLQWSYKYRLVVPTEIKALDFXXXXXXXXXXXXXXYQINQTTFRNHSD--------------------------SISCTENKNFQFFEKVLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCI--QKFDSENILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFI 1871
            +T++NAFCA+CN     + A    + TS  R+    T         P    R C  H  +  +C + S+      C     F   + +G   + IY+N YC LCN  + L+      LVVP E   L        N   LL+    + + F  HS+                          + + +E + +   +  LTV    +S++ LL   LV+      R  +S+ TL L+ ++    +  ++ + +E P    C   +I  H+ FLS+FFW ++ + D++K++   RL   ++   I                  L I A+C+         +L+P +    C+I    G + +F  P+   L+ +I +   +   I K  +Q          ++ +  L IKL  + G TWL  FVGVF NN  +  I
Sbjct:  159 VTYRNAFCALCN--YDLDNATTFWNATSKIRRYFKVTTPDMADENKPLHL-RPCAFHTRINDSCLEGSDSETVRRCHTY--FAPVKPKGNESEVIYKNIYCGLCNGADPLELECAPMLVVP-ETWFLPQLRSGRPNLLSLLRPVLTSDSCFSWHSNKCYIRAPQYRYNASVTGANASLVNGTNATASEQQPYDI-QNYLTVVCVSLSLLCLLLKGLVYILYKSSRTFSSRCTLCLSATLFWSQLIFLLVNSLEVPHS-VCTGSAIVLHYGFLSTFFWTSVLSFDIWKNVAGVRLTSGRSSGFIA--------YCLIAWGGPLAIVAICVLLNWTAPTFVLSPRYARRGCWIGSFWGQVTFFLFPMFALLILDIGLYVHIVYHIRKTVKQAANFDFRGGAQRSHMALFIKLGFIIGTTWLLGFVGVFVNNVAMDII 577          

Query: 1155 FEKVLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENP----SKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSENILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFI 1871
            ++ + T   + +S++ L   ++++       N   K  + L+ ++L   + NI F++  +     S   CL  ++  H+ +L+SFFWM + + D+YK   S  L +        +R    Y L  +  P    +  +C   F  ENI  P +G   C+IN+    L++F IPL   +  N I   +    + K N +T  + +  N  + N +L +KLS+  G TW+   V  F  N I  F+
Sbjct:  351 WKSLFTEVIQKLSIVGLSLHLIIYSLVPKLHNVPGKCLMSLSFALL---MANICFAIAASTYIIQSSSLCLTVALFVHYFYLASFFWMNVISFDMYKCFDSGLLSLRS----WDNRCFLVYSLYSWLSPAAFVVVGLCFDVFTEENIFQPLYGFSLCWINRRSALLIYFGIPLTTIISVNTIFFTLTAMSLIKTNCETSLIRN--NQTEINILLHLKLSLTMGLTWIFGIVFAFTENTIFWFL 584          

Query: 1164 VLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSENILNPSFGEIQ-CFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEKKNF-ILCIKLSILFGATWLPAF 1832
             LT+    +SMISL+ ++  +    + RN   ++ L L I++L   +  + F V ++ ++  C+  +++ HF  LS+F WM + A DV+ + T P  R   +          +          ++TI+       D        +G  + CFI      L  F +P+ I LL N I        I  + ++T +  +     K N  I+C K++   G TW+ A+
Sbjct:  413 ALTIAGCALSMISLVVLIFSYAVLPELRNLPGRVVLSLAITMLLYHL--LYFLVNQSDTRALCVAVAVSLHFALLSAFCWMNVLAFDVHHTFTKPGQRRTASRGHCPGTYAIYAAYSWGIPLAIVTISF----SVDLSGSWRIGYGRGEYCFIENPSAMLYLFLLPVAIILLYNFIALFHTMWHIRAVRKKTSKASN--QQRKPNLPIICFKMTSAMGITWVLAY 629          

Query:  426 SETHCYCDDQCSLFGDCCHKHQQHHEPIASCHDGYYVIDKCLYKST--------------DGNLKDKCERKSEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEFARVEK-------HKTSLKRKKDNTTEKSNYKYTFPKEFQRICHENVIITCDDDSEDALKLLCRNQPTFYVTENRGMVQKIYRNAYCF-LCN-TNSLQWSYK 995
            S+  C+CDD C  F DCCH +++     +       V D C ++ +              DG      +R S +  ++ +  +P           ++N FCAVC   ++  + R E          T++ + +         +Y+ P    R  H   I          L       P+ +VTEN   + K + ++Y F +C  TN +Q+ YK
Sbjct:   46 SQPKCFCDDMCVAFKDCCHDYEKKCGRPSVIESRESVEDICTFRRSHSTPYGFIFKRTCPDGTAHALSQRCSTVRDDDYMSSLPVIDVTSRTP--YRNLFCAVCRKADEISWWRAEAVCPNSTIDYTNMSKVRHFIASNCTMRYS-PSNAIRDLHPICI--------PPLTTPIIGTPSSHVTENVTEIIKEFCDSYAFPVCVITNGVQYMYK 247          

Query: 1164 VLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDS--ENILNPSFGEIQCFINQLIGGLVWFFIP 1658
            ++T+    +SM++L+F+ +  G   + RN   KI + L  ++L   V  ++  V  N  +  C   +I  HF  L++F WM + A DV+++ T      N+  A+++S +                I  +C+   DS     L+   G   C+I+   G L  F IP
Sbjct:  605 IMTLAGSTISMLALIFLFVCHGYFPELRNFPGKIQINLAAALLMFHVFFLMVGV--NSVRGLCKVVAIGIHFFLLAAFLWMAVMAYDVHRTFT------NQEKAMVQSSRRLLKVYALVAWITPAAIVILCL-VIDSLLSGSLDYGTGAF-CYISSRWGLLFAFVIP 761          

Query:  411 SRCVGSE----THCYCDDQCSLFGDCCHKH-----------QQHHEPIASCHDGYYVIDKCLYKSTDGNLKDKCERKSEISVNN---LLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEFARVE 731
            +RC  SE      CYCD  C+  GDCC+ +           ++   P   C +GYY+   C  ++TD  L  +C    E    N   LL ++P      N ++T+KN++CA C+   +  +   E
Sbjct:  217 NRCGASERTTQQKCYCDVICNEIGDCCYDYRSKCNITSTAPRRESTPKRQCSNGYYIARTCP-ENTDRYLDGQCTADGETPSTNDRDLLRNLPVLD--RNTNVTYKNSYCAKCHMATKLTYWTAE 338          

Query:  426 SETHCYCDDQCSLFGDCCHKH----------QQHHEPIASCHDGYYVIDKCLYKSTDGNLKDKCERKSEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQ--FEFARVEKHKTSLKRKKDNTT-------EKSNYKYTFPKEFQRICHENVIITCD---------DDSEDALKLLCRN-----QPTFYVTENRGM-VQKIYRNAYCFLC-NTNSLQ 983
            S + CYCDD CS  GDCC+ +          ++      +C DG   I +C   +            +     NLL   P Y   + VS  ++N  CA+CN      F + +V   K S+     N T       +K  ++Y    + +++  ++   TC          D  +  +  LC        PT  +   RG+ + K  RN +C +C N  S Q
Sbjct:    5 SPSKCYCDDLCSSLGDCCYDYIPRCENATEWRKLGPGTRTCVDGVIAISRCPSLTIASKAVISGCHSASSQPENLLSGAPVYDYAQGVS--YRNLDCALCNNATNVTFWYLKVACPK-SVSTALGNMTALLIDVRDKCTWEYQVKNDMKKLTCQSPDDTCKRGLSGDSVIDRYQAIVHDLCHMYALPIYPTLMLHVGRGLQIFKPIRNPHCLVCLNITSPQ 222          

Query:  396 FQVDDSRCVGS----------ETHCYCDDQCSLFGDCCHKHQQ------HHEPIAS--CHDGYYVIDKCLYKSTDGNLKDKC-ERKSEI--SVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEF 719
            F++    C+G           ET CYCD  C   GDCCH +++        +P     C + Y V + C  K TD  L   C E   EI     +LL ++  + + +N+S  ++N FCA CNG     +
Sbjct:   34 FEIPSLTCLGRCEVHSERFQIETLCYCDSICLQIGDCCHDYRKVCKAKLSEKPQVKQVCSNHYIVTNSC-PKGTDQYLDGLCSETHGEILRRPYDLLRNLHVFDHDKNIS--YRNVFCARCNGARNTSY 159          

Query:  369 AKSLESQASFQVDDSRCVGSETHCYCDDQCSLFGDCCHKHQQHHEPIASCHDGYYVIDKCLYKSTDGNLKDKCERKSEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEFARVEKHKTSLKRKKDNTTEKSNYKYTFPKEFQRICHENVIITCDDDSEDALKLLCRNQPTFYVTENRGMVQKIYRNAYCFLCNTNSLQWSYKYRLVVPTEIKALDFXXXXXXXXXXXXXXYQINQTTFRNHSDSISCTENKNFQFFEKVLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSENILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFIXXXXXXXXXXXXXXCFIYGMDVHKTTTKYIRSITENISSFATRKQSNASI 2021
            AKSLESQASFQVDDSRCVGSETHCYCDDQCS+FGDCCHKHQQHHEPIASCHDGYYVIDKCLYKSTDGNLKDKCERKSEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEFARVEKHKTSLKRKKDNTTEKSNYKYTFPKEFQRICHENVIITCDDDSEDALKLLCRNQPTFYVTENRGMVQKIYRNAYCFLCNTNSLQWSYKYRLVVPTEIKALDFNEWCLNNCNELLKLYQINQTTFRNHSDSISCTENKNFQFFEKVLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKT +LIKSRKLKFYFLGGYGLPLLLTITAVCIQKFDSENILNPSFGEIQCFINQLIGGLVWFFIPLCICLLTNIIICCVLYRFIYKINQQTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFIGGLLSSLQGLSLSLCFIYGMDVHKTTTKYIRSITENISSFATRKQSNASI
Sbjct:   13 AKSLESQASFQVDDSRCVGSETHCYCDDQCSMFGDCCHKHQQHHEPIASCHDGYYVIDKCLYKSTDGNLKDKCERKSEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEFARVEKHKTSLKRKKDNTTEKSNYKYTFPKEFQRICHENVIITCDDDSEDALKLLCRNQPTFYVTENRGMVQKIYRNAYCFLCNTNSLQWSYKYRLVVPTEIKALDFNEWCLNNCNELLKLYQINQTTFRNHSDSISCTENKNFQFFEKVLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTISLIKSRKLKFYFLGGYGLPLLLTITAVCIQKFDSENILNPSFGEIQCFINQLIGGLVWFFIPLCICLLTNIIICCVLYRFIYKINQQTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFIGGLLSSLQGLSLSLCFIYGMDVHKTTTKYIRSITENISSFATRKQSNASI 563          

Query:  426 SETHCYCDDQCSLFGDCCHKHQQHHEP-----IASCH-------DGYYVIDKCLYKSTDGNLKDKCERKSEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEFARVEKHKTSLK-----RKKDNTTEKSNYKYTFP---KEFQRICHENVIITCDDDSEDALKLL---CRNQPTFYVTENRGMVQKIYRNAYCFLC-NTNSLQWSYKYRLVVPTEIKALDFXXXXXXXXXXXXXXYQINQTTFRNHSDSISCTENKNFQ------------------FFEKVL---TVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISV-----LSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSEN-ILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFIXXXXXXXXXXXXXXCFIYGMDVHKTTTKYIRSITENISSFATRKQSN 2012
            S+  C+ D QC L+GDCC+ HQ H +P     + SC           ++I+KC  K+ +  L D C +K       L   +P   N +   + + N FCA CN +  F +  V+ +   L+            +  N+   FP   +  QR C   +I  C +      K +   C N    Y       +QK Y+N +C  C N N        R  +P  I+   F+             Y +N   +    +  +  E KNF                     E V+   +  F  +S++SL F+++++      +N    +T+ L+I +     +SL VTN    +V++ S   C Y +I +HF  LS+F WM ++ALD+ ++  +    INK       +    YF+  + +   +   +V I+ FD  N  L P +G   C+     GGL+W+FIP+C+ LL NII C  ++  ++K  ++   + +  N       LC++L+ +FG  ++   + +F    IL  +G +++ LQG  L+LCF+    V       + +ITE+IS  +T  + +
Sbjct:   22 SDRICHSDPQCPLYGDCCYGHQDHGKPGLLKDVLSCKPYNKLFPSAMWLINKC--KNLNHPLSDFCTKKIFYPKAPLKSWIPVISNRK---IIYDNLFCAKCNEEIDFTYLPVKVNCGPLEIYDYASANQAVIDNPNHCEIFPYFNRTLQRSCEGEIITNCTNTKLIQNKFVIDKCENGEKDYFVFR---LQK-YKNVFCCKCWNKNCFG-----RRKLP-NIRNSPFS-------------YLLNFNDWEKQENKETVKE-KNFTQENNSSNNTNSTLDYSTGMGETVIYHISFAFTCLSLVSLFFLIILYLTHQVFKNLGGYLTICLSICLWLINFMSLLVTNT--QIVKSAS---CKYLAIFHHFVALSTFVWMAVYALDLLQTFGTKSASINKNRGW---KTFCIYFICVFAVSGCVVGISVIIEYFDKTNSTLRPQYGGPHCWFTSKFGGLIWYFIPVCLLLLWNIITCGFVFYQLFKTAKECRIINN--NDLNSTLWLCMRLTAVFGVGYVLQIIAIFTQLNILISLGSMVNCLQGFMLTLCFVCTKRVRSQLRNRLLTITESISKSSTANRPS 562          

Query:  414 RCVGSETHCYCDDQCSLFGDCCHKHQQHHEPIA------------SCHDGYYVIDKCLYKSTDGNLKDKCERK----SEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEFARVE------------KHKTSLKRKKDNTTEKSNYKYTFPKEFQRICHENVIITCDDDSEDALKLL---CRNQPTFYVTENRGMVQKIYRNAYCFLCNTNSLQWSY---KYRLVVPTEIKALDFXXXXXXXXXXXXXXYQINQTTFRNHSDSISCTENKNFQFFEKVLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENPS---KRFCLYFSIAYHFCFLSSFFWMTIFALDVY-----KSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSENILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQ--QTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFIXXXXXXXXXXXXXXCFIYG-------MDVHKTTTKYIRSITENISSFATRKQS 2009
            +C  +  +C CDD+C+L+GDCC  H+  ++  +            S  +  YV+DKC  K+   ++  K  RK    S+I V + +  +   G      + F+N+FCA CN ++ + +  +                 ++ + +D+   +   +       +RIC   +I  C +  ED  + +   C N P  +  E  G +  +YRN +C  C      W     + +++ PT I  +    + LN  + +    ++ +   +N+++     ++KN ++F   ++ TF  +SMISL  +++++       N    +T+ L+I    L + N    +V++P+     FC Y  I  HF  + +F WM I+ALD+      KS  S + +  KTF         +  +G     L++T++ V     ++   + P++G   C+    +GG VW+FIP+CI LL N   C +++  I K ++  Q V    S ++      LCI+L+ +FG  ++   + +  +   L   G  ++ LQG  L+ CFI+        +DV  + T       EN+  + T  +S
Sbjct:   21 KCEKNSEYCNCDDKCTLYGDCCSGHESFNKTGSLRNILKCKLFKPSVAESIYVVDKC--KNNTKHILSKLCRKEVIFSKIPVKSFIPVINENG------VIFENSFCAKCNNEDLYSYLNISISCPDVNITDIYDANQAIAKSRDSCEIQPEIE----SNIKRICKTKLIDFCSNSFEDIGENITGKCTNGPESF--EVHGEI--LYRNTFCCKC------WKIHCRRLQVMKPTSILDMSTFSYLLNFNDWVESEDEVYKPE-QNNTEFDEIIKSKNLKYFVYYISFTFTCLSMISLTVLIVLYITQKVFHNFGGYLTICLSIC---LWLINFCTLLVQSPNIVNSSFCQYLGIFQHFITICNFIWMAIYALDLLQTFGVKSFNSSKKKTWKTFCF-------YCLVGFSCSGLIVTLSTVLEFTLETNCTIRPNYGGTHCWFTNKLGGTVWYFIPICILLLWNFGACILVFYRIIKTSKECQLVSNDQSYSI----LWLCIRLTSVFGFGYIFQIIAILTHFQPLIVFGSFVNCLQGCLLACCFIWTKRVRIIFVDVLTSFTDIFSKSNENVDKYKTTNKS 566          

Query:  417 CVGSETHCYCDDQCSLFGDCCHKHQQHH-----EPIASC-------HDGYYVIDKCL----YKS---TDGNLKDKCERKSEISVNNLLYHVPTYGNYENVSLTFKNAFCAVCNGKNQFEFARVE----KHKTSLKRKKDNTTEKSNYKYT----FPKEFQRICHENVIITCDDDSE---DALKLLCRNQPTFYVTENRGMVQKIYRNAYCFLCNTNSLQWSYKYRLVVPTEIKALDFXXXXXXXXXXXXXXYQINQTTFRNHSDSISCTENKNFQFFEKVLTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISVLSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSEN--ILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFIXXXXXXXXXXXXXXCFIYGMDVHKTTT 1952
            C  S+ +C CD  C  FGDCC  H++       E I+SC       ++   VI+KC+    Y S   T   +  K   KS  +V             EN  L ++N +CA CN   ++++  +      H  +  ++ +    KS Y  +       E QR C  N+   C +      D +  +C N     V++ R      YRN +C  C+  ++    +  L +     A  F+       NE+     + Q+   N   + +  E   ++ F+K  T  F  +SM+ L  ++L++   +  RN    +T+ L+  +      N++    +      C Y  I+  F  L  F WM +++LD+ ++       I K     K+ K   ++       + + + +  I +F   N     P +G   C+   +  GL+W+FIP+C+ LL N + C +++  I K +++   V            LC++L+ +FG  ++     +     IL  I  + +SLQG  L +CF +   V    T
Sbjct:   20 CRKSDQYCQCDKICVQFGDCCPGHEKFQQTGSLESISSCKVFAKNSYENMRVINKCVNDNHYYSKYCTKELMDPKLPIKSFAAVMG-----------EN-KLIYENYYCARCNNIKRYQYFSLSVSCFGHNITNFKQVNEIMIKSPYSCSILPLIDSELQRTCFINLTRLCQEPLSKRFDNVSDMCLNGKLDIVSDGRNF----YRNDHC--CSCRNISCFKQIPLALDVASSAFSFSLNFAAWENEVQTK-PVPQSNLTNKYFTHNVYE-IIYKIFDKT-TEVFTFLSMVCLFILILLYTTQSMFRNFGGYLTVCLSTCLWLSNFFNLLVFYKDFEKSFACTYIGISQQFFNLGMFVWMAVYSLDLLQTFGFRSTNIGKK----KTLKSFCFYCITGFSCVAINVGSAIIVEFTLPNNSTFRPKYGGRYCWFTNIPSGLIWYFIPVCLLLLWNSVTCVIVFYRIIKTSKECRVVQKK--ESNSTLWLCVRLTTVFGLGYVLQIFAILSKVDILVRILVVFNSLQGCFLMICFFWAKRVRAILT 536          

Query: 1167 LTVTFRIVSMISLLFMVLVFGCTNDHRNQASKITLFLTISV-----LSLCVTNIIFSVVENPSKRFCLYFSIAYHFCFLSSFFWMTIFALDVYKSITSPRLRINKTFALIKSRXXXXXXXXXXXXXXXXTITAVCIQKFDSEN-ILNPSFGEIQCFINQLIGGLVWFFIPXXXXXXXXXXXXXXXYRFIYKINQQTVEVGHSLNVEKKNFILCIKLSILFGATWLPAFVGVFFNNYILKFIXXXXXXXXXXXXXXCFIYGMDVHKTTTKYIRSITENISSFATRKQ 2006
            ++  F  +S++SL F+++++      +N    +T+ L+I +     +SL VTN    +VE+ S   C Y +I +HF  LS+F WM ++ALD+ ++  +  +  NK   L   +    Y L G+     +   +V  + FD  N  L P +G   C+     GGL+++FIP+C+ LL N I+C  ++  ++K  ++   V            LC++L+ +FG  ++     +F    IL  +G +++ LQG  L+LCF+            + +ITE+IS  +T  +
Sbjct:  128 ISFAFTCLSLVSLFFLIILYLTHQVFKNFGGYLTICLSICLWLINFMSLLVTNT--QIVESAS---CKYLAIFHHFVALSTFVWMAVYALDLLQTFGTKLVNANKKRGL---KSFSVYCLIGFSTSGSVVGISVITEYFDKTNSTLRPQYGGPYCWFTSKFGGLIYYFIPVCLLLLWNFIMCSFVFYQLFKTAKECRIVKK--KDANSTLWLCMRLTAVFGVGYVLQIFAIFTQLEILISLGSMVNCLQGFMLTLCFVCTKRARSLLRNRLLTITESISKSSTANK 403