Transient receptor potential cation channel subfamily M member 6

Overview


Name	Transient receptor potential cation channel subfamily M member 6
Smed ID	SMED30005926
Length (bp)	4027

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Transient receptor potential cation channel subfamily M member 6 (SMED30005926) t-SNE clustered cells

Violin plots show distribution of expression levels for Transient receptor potential cation channel subfamily M member 6 (SMED30005926) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transient receptor potential cation channel subfamily M member 6 (SMED30005926) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30005926

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30005926	SMESG000064642.1 SMESG000064637.1	dd_Smed_v4_13119_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30005926	SMESG000064642.1 SMESG000064637.1	dd_Smed_v4_13119_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30005926	SMESG000064642.1 SMESG000064637.1	dd_Smed_v4_13119_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
ventral epidermis	SMED30005926	SMESG000064642.1 SMESG000064637.1	dd_Smed_v4_13119_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
ovary	SMED30005926	SMESG000064642.1 SMESG000064637.1	SMED30005926	smed_20140614	PMID:279364
testis	SMED30005926	SMESG000064642.1 SMESG000064637.1	SMED30005926	smed_20140614	PMID:279364

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Homology

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992])

HSP 1 Score: 322.783 bits (826), Expect = 1.799e-90
Identity = 296/1066 (27.77%), Postives = 493/1066 (46.25%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH--------------KKDKIPYNKVND--WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-------------------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED-----------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ F+  +C   +  +K+      +C CG L  +H               + ++  N +    WSI    +  PT++FG IEF G   +N  +  +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA+++        +K    +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E           +G  ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT + LE+LY                    + P  + +                          RT++H       N  G  +    K+ G  +D                    + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  +K      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:   62 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALKD------HASKSRGKICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKYGAE--VKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSE-----------EG-GLINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 1061

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992])

HSP 1 Score: 321.627 bits (823), Expect = 3.195e-89
Identity = 297/1066 (27.86%), Postives = 493/1066 (46.25%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH--------------KKDKIPYNKVND--WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-------------------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED-----------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ F+  +C   +  +K+      +C CG L  +H               + ++  N +    WSI    +  PT++FG IEF G   +N  +  +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT + LE+LY                    + P  + +                          RT++H       N  G  +    K+ G  +D                    + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  +K      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:   62 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 1061

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992])

HSP 1 Score: 293.893 bits (751), Expect = 1.936e-80
Identity = 274/967 (28.34%), Postives = 451/967 (46.64%), Query Frame = 3

Query:  504 FVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-------------------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED-----------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT + LE+LY                    + P  + +                          RT++H       N  G  +    K+ G  +D                    + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  +K      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:    2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 908

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992])

HSP 1 Score: 286.189 bits (731), Expect = 4.981e-78
Identity = 275/978 (28.12%), Postives = 450/978 (46.01%), Query Frame = 3

Query:  504 FVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNK----------------------------EPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHF--------LGRNFSNGLGDV---------------------KDLLTKIFGYYEDQCAMC------------------DEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +  N                             + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT + LE+LY       N   T++H         L  ++   L D+                     + L   +FG   D   +                   D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  +K      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:    2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSN---TLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 923

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Match: TRPM3 (transient receptor potential cation channel subfamily M member 3 [Source:HGNC Symbol;Acc:HGNC:17992])

HSP 1 Score: 286.189 bits (731), Expect = 4.981e-78
Identity = 275/978 (28.12%), Postives = 450/978 (46.01%), Query Frame = 3

Query:  504 FVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNK----------------------------EPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHF--------LGRNFSNGLGDV---------------------KDLLTKIFGYYEDQCAMC------------------DEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +  N                             + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT + LE+LY       N   T++H         L  ++   L D+                     + L   +FG   D   +                   D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  +K      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:    2 YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSN---TLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 923

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gtl-2 (Gon-Two Like (TRP subfamily) [Source:UniProtKB/TrEMBL;Acc:Q20766])

HSP 1 Score: 227.639 bits (579), Expect = 4.858e-60
Identity = 238/1004 (23.71%), Postives = 421/1004 (41.93%), Query Frame = 3

Query:  261 FIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKV---------NDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKIL----EHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHE--RFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRI--KENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDG--VPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV--KEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY--EDCPRSFNLKRTIFHF-------------LGRNFSNGLGDVKDL--LTKIF-GYY----------------------------EDQCAMCDEE---IIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENL------AIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTW------RAGFNINLFQCILC----IFLPF------------------LIYRRSFDNS-------YVIHESKKKDDTSNKGYFT----------NSGNWPL-------------------KLVQFYLAPQTKF---CIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWN--FNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCS--KTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISK 2831
            +I+  F   +C  F    K+      +C CG   S H      ++ +           W+I +  +T  T++FG I F G    +    ++VRLS++    DVM LM   W +E   L I+V GG  NF+++++   +F +G++KA +TT A I+TSGL+ G+ R V  A+          A+  + +  +GIAPWG +K K+ L    EH    +    V+  + +     LN  H+++L  D     RF          R+ LE  ++    N   +PVV  L+EG           +  K ++P ++C G+GRA+D++  A R +          DG     + E  RN +K    + +        E    I E + ++ L+ +F    +E+ D++  IL +++++ +   D        QL+L L WNRVD+AK  +FS     S +     + +++   + +FVE  L+NG  M +FL+   LE LY  +D   + +++  + +F             +G+     +G+   L   ++ F G Y                            +DQ    +EE     +PF +L IW+VL   H  A   W   E+++   L+A ++YK   +++  +   +E     K  F+N       AI+LL++C+ AD +    ++  E   WG   CL +A  A  + F++   CQ  L   W      R+G N+ +   ++C    +F+ +                  L Y R    S       Y     ++K+    KG +T          NSG   +                   +   FY +P TKF   CI  L F  +      +       ++ + +E +  IY + +++E   ++   + +++ +++K ++   +N W    +L                L  +   +V +YR S  + + S     FY++    +SVH  LGP I M +K
Sbjct:   88 WIENTFEKRECIRFAALPKD----PERCGCGRPLSAHTPASTFFSTLPVHLLEKEQQTWTIANNTQTSTTDAFGTIVFQGG--AHAHKAQYVRLSYDSEPLDVMYLMEKVWGLEAPRLVITVHGGMSNFELEERLGRLFRKGMLKAAQTTGAWIITSGLDSGVVRHVAKALDEAGI----SARMRSQIVTIGIAPWGVIKRKERLIRQNEHVYYDVHSLSVNANVGI-----LNDRHSYFLLADNGTVGRF----GADLHLRQNLENHIATFGCNGRKVPVVCTLLEGGISSINAIHDYVTMKPDIPAIVCDGSGRAADIISFAARYINS--------DGTFAAEVGEKLRNLIKMVFPETD------QEEMFRKITECVIRDDLLRIFRYGQEEEEDVDFVILSTVLQKQNLPPD-------EQLALTLSWNRVDLAKSCLFSNGRKWSSDVLEKAMNDALYWDRVDFVECLLENGVSMKNFLSINRLENLYNMDDINSAHSVRNWMENFDSMDPHTYLTIPMIGQVVEKLMGNAFQLYYTSRSFKGKYDRYKRINQSSYFHRKRKIVQKELFKKKSDDQINDNEEEDFSFAYPFNDLLIWAVLTSRHGMAECMWVHGEDAMAKCLLAIRLYKATAKIAEDEYLDVEEA---KRLFDNAVKCREDAIELLDQCYRADHDRTLRLLRMELPHWGNNNCLSLAVLANTKTFLAHPCCQILLAELWHGSLKVRSGSNVRVLTALICPPAILFMAYKPKHSKTARLLSEETPEQLPYPRESITSTTSNRYRYSKGPEEQKETLLEKGSYTKKVTIISSRKNSGVASVYGSASSMMFKREPQLNKFERFRAFYSSPITKFWSWCIAFLIFLTTQTCILLLETS----LKPSKYEWITFIYTVTLSVEHIRKLMTSEGSRINEKVKVFYAKWYNIWTSAALL--------------FFLVGYGFRLVPMYRHSWGRVLLSFSNVLFYMKIFEYLSVHPLLGPYIQMAAK 1030

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971])

HSP 1 Score: 175.252 bits (443), Expect = 9.553e-44
Identity = 148/566 (26.15%), Postives = 258/566 (45.58%), Query Frame = 3

Query:  105 KMNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHK-------------------KDKIPYNKVND----------------WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTK---NKEPIPVVLLLIEGEYDVFFEASKRIK--ENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKE--DHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY 1676
            ++N+ VS T +S +Q  L     +Q RF        SN++ N ++       ++++ F   +C  F+  S++L     KC CG  +  H+                   + +   + VND                WS+     ++ T +FG++EF G    +    ++VR++ +     +M L    W I    L I+V GGT NF ++ K   +F +GL+KA  TT A I+TSG + G+ + V  A++  Q      +   N + C+GIAPWG +K ++       T+  Y  S++   T    LN  H+++L VD      Y        R+ LE  +SQ+ K       +PVV +++EG           +     VP+V+C G+GRA+DLL  A + + +        DG  +LP+  R  +   +      +    +  L+ +      + L+T+F + E  +HD++ AIL +L+K  + ++  +L            WNRVDIA+  +F+      +      + E++I+ + +FV L L+ G  M  FLT + L++LY
Sbjct:  145 RLNEDVSATANS-AQLVLPTPLFNQMRF------TESNMSLNRHN-------WVRETFTRRECSRFIASSRDLH----KCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGG--PHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQ------SAQRNKIVCIGIAPWGLLKKREDFIGQDKTVPYYPSSSKGRFT---GLNNRHSYFLLVDNGTVGRYGAEVI--LRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTE--------DG--LLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNLLTIFRLGEQGEHDVDHAILTALLKGQNLSAADQLALAL-------AWNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELY 662

HSP 2 Score: 75.485 bits (184), Expect = 2.944e-13
Identity = 45/162 (27.78%), Postives = 76/162 (46.91%), Query Frame = 3

Query: 1806 AMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFEN---LAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF------NINLFQCILCIFLPFL 2264
            +  + +  +P+ EL IW+VL +  + A   W+  EE++  ALVA ++YK L   +  D   +E     K Y E    L+++LL+ C+  D      ++  E   W   TCL +A    ++ F++   CQ  L   W  G       NI +   ++C   PF+
Sbjct:  842 SQTEPDFRYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICP--PFI 1001

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971])

HSP 1 Score: 175.252 bits (443), Expect = 1.022e-43
Identity = 148/566 (26.15%), Postives = 259/566 (45.76%), Query Frame = 3

Query:  105 KMNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHK-------------------KDKIPYNKVND----------------WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTK---NKEPIPVVLLLIEGEYDVFFEASKRIK--ENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKE--DHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY 1676
            ++N+ VS T +S +Q  L     +Q RF        SN++ N ++       ++++ F   +C  F+  S++L     KC CG  +  H+                   + +   + VND                WS+     ++ T +FG++EF G    +    ++VR++ +     +M L    W I    L I+V GGT NF ++ K   +F +GL+KA  TT A I+TSG + G+ + V  A++  Q      +   N + C+GIAPWG +K ++       T+  Y  S++   T    LN  H+++L VD      Y        R+ LE  +SQ+ K       +PVV +++EG           +     VP+V+C G+GRA+DLL  A + + +        DG  +LP+  R  +   +      +    +  L+ +      + L+T+F + E  +HD++ AIL +L+K  + ++  +L    +       WNRVDIA+  +F+      +      + E++I+ + +FV L L+ G  M  FLT + L++LY
Sbjct:  246 RLNEDVSATANS-AQLVLPTPLFNQMRF------TESNMSLNRHN-------WVRETFTRRECSRFIASSRDLH----KCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGG--PHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQ------SAQRNKIVCIGIAPWGLLKKREDFIGQDKTVPYYPSSSKGRFT---GLNNRHSYFLLVDNGTVGRYGAEVI--LRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTE--------DG--LLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNLLTIFRLGEQGEHDVDHAILTALLKGQNLSAADQLALALA-------WNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELY 763

HSP 2 Score: 75.485 bits (184), Expect = 3.074e-13
Identity = 45/154 (29.22%), Postives = 73/154 (47.40%), Query Frame = 3

Query: 1830 HPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFEN---LAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF------NINLFQCILCIFLPFL 2264
            +P+ EL IW+VL +  + A   W+  EE++  ALVA ++YK L   +  D   +E     K Y E    L+++LL+ C+  D      ++  E   W   TCL +A    ++ F++   CQ  L   W  G       NI +   ++C   PF+
Sbjct:  951 YPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICP--PFI 1102

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gon-2 (Transient receptor potential channel [Source:UniProtKB/Swiss-Prot;Acc:Q93971])

HSP 1 Score: 174.866 bits (442), Expect = 1.148e-43
Identity = 148/566 (26.15%), Postives = 259/566 (45.76%), Query Frame = 3

Query:  105 KMNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHK-------------------KDKIPYNKVND----------------WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTK---NKEPIPVVLLLIEGEYDVFFEASKRIK--ENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKE--DHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY 1676
            ++N+ VS T +S +Q  L     +Q RF        SN++ N ++       ++++ F   +C  F+  S++L     KC CG  +  H+                   + +   + VND                WS+     ++ T +FG++EF G    +    ++VR++ +     +M L    W I    L I+V GGT NF ++ K   +F +GL+KA  TT A I+TSG + G+ + V  A++  Q      +   N + C+GIAPWG +K ++       T+  Y  S++   T    LN  H+++L VD      Y        R+ LE  +SQ+ K       +PVV +++EG           +     VP+V+C G+GRA+DLL  A + + +        DG  +LP+  R  +   +      +    +  L+ +      + L+T+F + E  +HD++ AIL +L+K  + ++  +L    +       WNRVDIA+  +F+      +      + E++I+ + +FV L L+ G  M  FLT + L++LY
Sbjct:  185 RLNEDVSATANS-AQLVLPTPLFNQMRF------TESNMSLNRHN-------WVRETFTRRECSRFIASSRDLH----KCGCGRTRDAHRNIPELTSEFLRQKRSVAALEQQRSISNVNDDINTQNMYTKRGANEKWSLRKHTVSLATNAFGQVEFQGG--PHPYKAQYVRVNFDTEPAYIMSLFEHVWQISPPRLIITVHGGTSNFDLQPKLARVFRKGLLKAASTTGAWIITSGCDTGVVKHVAAALEGAQ------SAQRNKIVCIGIAPWGLLKKREDFIGQDKTVPYYPSSSKGRFT---GLNNRHSYFLLVDNGTVGRYGAEVI--LRKRLEMYISQKQKIFGGTRSVPVVCVVLEGGSCTIRSVLDYVTNVPRVPVVVCDGSGRAADLLAFAHQNVTE--------DG--LLPDDIRRQVLLLVETTFGCSEAAAHRLLHELTVCAQHKNLLTIFRLGEQGEHDVDHAILTALLKGQNLSAADQLALALA-------WNRVDIARSDVFAMGHEWPQAALHNAMMEALIHDRVDFVRLLLEQGINMQKFLTISRLDELY 702

HSP 2 Score: 75.485 bits (184), Expect = 2.786e-13
Identity = 45/162 (27.78%), Postives = 76/162 (46.91%), Query Frame = 3

Query: 1806 AMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFEN---LAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF------NINLFQCILCIFLPFL 2264
            +  + +  +P+ EL IW+VL +  + A   W+  EE++  ALVA ++YK L   +  D   +E     K Y E    L+++LL+ C+  D      ++  E   W   TCL +A    ++ F++   CQ  L   W  G       NI +   ++C   PF+
Sbjct:  882 SQTEPDFRYPYSELMIWAVLTKRQDMAMCMWQHGEEAMAKALVACRLYKSLATEAAEDYLEVEICEELKKYAEEFRILSLELLDHCYHVDDAQTLQLLTYELSNWSNETCLALAVIVNNKHFLAHPCCQILLADLWHGGLRMRTHSNIKVVLGLICP--PFI 1041

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Match: gtl-1 (GTL-1; Gon-Two Like (TRP subfamily) [Source:UniProtKB/TrEMBL;Acc:G5ECM4])

HSP 1 Score: 172.17 bits (435), Expect = 8.758e-43
Identity = 141/523 (26.96%), Postives = 236/523 (45.12%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKD---------------KIP-------------YNKVN----DWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTII-KYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIK--ENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRT 1712
            K +I+ +     C +FV  S+  S +   C CG+ +S+H ++                +P              N+VN     WSI S  E VPT+++G I F G         ++ R+S + +  D++ LM   W ++   L I++ GG   F ++ K    F +G++K  K+T+A I+TSGL+ G+ + +  A+ +     +      N +  +GIA WG +K +        T+     V N   L E   LN NH+++LF D      Y        R+ LE  L+Q  K +  IP+V +++EG           +     +P+++C G+GRA+D+L  A + + +        +G   L +  RN L   +      +P    + +  I E    + L+T+F + E    DL+  I+  L+K  + +          QL L L WNR DIA+ +IF+     + ++    + E++ N + +FV L L+NG  M  FLT   LE LY       N  RT
Sbjct:  103 KNWIECRLKMRQCSYFV-PSQRFSER---CGCGKERSKHTEEVLERSQNKNHPLNHLTLPGIHEVDTTDADADDNEVNLTPGRWSIQSHTEIVPTDAYGNIVFEG----TAHHAQYARISFDSDPRDIVHLMMKVWKLKPPKLIITINGGLTKFDLQPKLARTFRKGIMKIAKSTDAWIITSGLDEGVVKHLDSALHD-----HGNHTSKNHVVAIGIASWGMLKQRSRFVGKDSTVTYATNVFNNTRLKE---LNDNHSYFLFSDNGTVNRYGAEII--MRKRLEAYLAQGDKKRSAIPLVCVVLEGGAFTIKMVHDYVTTIPRIPVIVCDGSGRAADILAFAHQAVSQ--------NG--FLSDNIRNQLVNIVRRIFGYDPKTAQKLIKQIVECSTNKSLMTIFRLGESSREDLDHVIMSCLLKGQNLSP-------PEQLQLALAWNRADIARTEIFANGTEWTTQDLHNAMIEALSNDRIDFVHLLLENGVSMQKFLTYGRLEHLYNTDKGPQNTLRT 590

HSP 2 Score: 83.9593 bits (206), Expect = 7.685e-16
Identity = 50/173 (28.90%), Postives = 83/173 (47.98%), Query Frame = 3

Query: 1782 FGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRI---ETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF---NINLFQCILCIFLPFLIYRRSF 2282
            F   E++  M D    +P+ +L IW+VL +  + A   W   EE +  ALVA+++Y  L + + L T  I   +  + + D F  LA+++LE C    ++    ++  E   WG  TCL +A     +KF++   CQ  L   W+ G    N    + + C+  P LI+   F
Sbjct:  700 FSNLEEEANM-DFTFRYPYSDLMIWAVLTKRQKMAKLMWTHGEEGMAKALVASRLYVSLAKTASLATGEIGMSQDFTEFSDEFSELAVEVLEYCTKHGRDQTLRLLTCELANWGDETCLSLAANNGHRKFLAHPCCQMLLSDLWQGGLLMKNNQNSKVLTCLAAPPLIFLLGF 871

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339075)

HSP 1 Score: 265.388 bits (677), Expect = 1.595e-72
Identity = 278/1057 (26.30%), Postives = 465/1057 (43.99%), Query Frame = 3

Query:  225 FNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK-DKIPYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFV-KNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQ---RTKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDG--VPMLPEM--YRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED-----HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL--FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFN----LKRTIFHFLGRNFSNGLGDVKDLLTKIFG-----YYEDQ-------------CAMCDEEIIH-----------------------------PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSP---LDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF----NINLFQCILCIFLPFLIYRRSF----------------------DN----------------SYVIHESKKKD---------DTSNKGYFTNSGNW-------PLKL----VQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            F  N   +  + +I+  F   +C  F+   K+     TKC CG+ +  H+    I      D W         PT+++G IEF G    +    ++VRLS +   + +++L    WN+E+  L I+V GG  NF ++ K K    +GL+KA KTT A I T G N G+T+ VGDA+      L +  +    +  +GIAPWG V +N ++L H +  +  + +S+    ++   LN  H ++L VD   +  Y        R  LEK +S            PVV L+IEG  +      + + ++  VP+V+C G+GRA+DLL  AF       + +   DG   P+L  M  Y     +K  +  +   +K+ + L    +    + LIT+F ++E       +L+  IL +L K    +          QLSL L WNRVDIA+ +IF  V      N AL   + +++ + + +FV+L L+NG  M  FLT   LE+LY       N    + R +   + + +   L D+  ++ K+ G     YY  +                C +   +                             PF EL IW+VL +  + A   W   EE+L  +LV+ K+YK +   +    LDT   E L ++   FE+   KLL+  +  D E A  ++  E  +W   +CL +A  A  +  ++    Q  L   W  G     N N F+ IL + +PF I +  F                      DN                +Y + ++K  +         DT+    F N   +       PL+L     +FY AP TKF   S+A+   +  FS+ VL  M++M     E   I Y+  +  EK  E+   +   +  +    W +N WN  D   +IL  + +  RF    +    DI  +  C  +I      Y+YLR L ++ V+K LGP + M+ KM+  ++++++++ ++L+++G++ Q   +P +  + + +  +   PY+ ++GE+
Sbjct:    3 FETNWVFHQPRSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVERNHELLGHNR-EVPCHSISSP--RSKLAVLNNRHAYFLLVDNGTQAKYGAELI--LRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF-------VHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQEL---LQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSP-------PEQLSLALTWNRVDIARSEIF--VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSV-WAWNMWNPCDGAAIILFVIGLAFRF----RENTMDIGRVIYCVDSI------YWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 1008

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339082)

HSP 1 Score: 268.085 bits (684), Expect = 2.240e-72
Identity = 273/1029 (26.53%), Postives = 458/1029 (44.51%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK-DKIPYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFV-KNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQ---RTKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDG--VPMLPEM--YRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED-----HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL--FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFN----LKRTIFHFLGRNFSNGLGDVKDLLTKIFG-----YYEDQ-------------CAMCDEEIIH-----------------------------PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSP---LDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF----NINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKD----------------------------DTSNKGYFTNSGNW-------PLKL----VQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYW-WNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            + +I+  F   +C  F+   K+     TKC CG+ +  H+    I      D W         PT+++G IEF G    +    ++VRLS +   + +++L    WN+E+  L I+V GG  NF ++ K K    +GL+KA KTT A I T G N G+T+ VGDA+      L +  +    +  +GIAPWG V +N ++L H +  +  + +S+    ++   LN  H ++L VD   +  Y        R  LEK +S            PVV L+IEG  +      + + ++  VP+V+C G+GRA+DLL  AF       + +   DG   P+L  M  Y     +K  +  +   +K+ + L    +    + LIT+F ++E       +L+  IL +L K    +          QLSL L WNRVDIA+ +IF  V      N AL   + +++ + + +FV+L L+NG  M  FLT   LE+LY       N    + R +   + + +   L D+  ++ K+ G     YY  +                C +   +                             PF EL IW+VL +  + A   W   EE+L  +LV+ K+YK +   +    LDT   E L ++   FE+   KLL+  +  D E A  ++  E  +W   +CL +A  A  +  ++    Q  L   W  G     N N F+ IL + +PF I +  F +   + +  + +                            DT+    F N   +       PL+L     +FY AP TKF   S+A+   +  FS+ VL  M++M     E   I Y+  +  EK  E+   +   +  +   W WN   WN  D   +IL  + +  RF    +    DI  +  C  +I      Y+YLR L ++ V+K LGP + M+ KM+  ++++++++ ++L+++G++ Q   +P +  + + +  +   PY+ ++GE+
Sbjct:   13 RSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVERNHELLGHNR-EVPCHSISSP--RSKLAVLNNRHAYFLLVDNGTQAKYGAELI--LRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF-------VHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQEL---LQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSP-------PEQLSLALTWNRVDIARSEIF--VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNM--WNPCDGAAIILFVIGLAFRF----RENTMDIGRVIYCVDSI------YWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 989

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339074)

HSP 1 Score: 264.618 bits (675), Expect = 2.417e-71
Identity = 279/1052 (26.52%), Postives = 458/1052 (43.54%), Query Frame = 3

Query:  243 KNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK-DKIPYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFV-KNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQ---RTKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDG--VPMLPEM--YRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED-----HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL--FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFN----LKRTIFHFLGRNFSNGLGDVKDLLTKIFG-----YYEDQ-------------CAMCDEEIIH-----------------------------PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSP---LDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF----NINLFQCILCIFLPFLIYRRSF----------------------DN----------------SYVIHESK---------KKDDTSNKGYFTNSGNW-------PLKL----VQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYW-WNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            K+  + +I+  F   +C  F+   K+     TKC CG+ +  H+    I      D W         PT+++G IEF G    +    ++VRLS +   + +++L    WN+E+  L I+V GG  NF ++ K K    +GL+KA KTT A I T G N G+T+ VGDA+      L +  +    +  +GIAPWG V +N ++L H +        S    L     LN  H ++L VD   +  Y        R  LEK +S            PVV L+IEG  +      + + ++  VP+V+C G+GRA+DLL  AF       + +   DG   P+L  M  Y     +K  +  +   +K+ + L    +    + LIT+F ++E       +L+  IL +L K    +          QLSL L WNRVDIA+ +IF  V      N AL   + +++ + + +FV+L L+NG  M  FLT   LE+LY       N    + R +   + + +   L D+  ++ K+ G     YY  +                C +   +                             PF EL IW+VL +  + A   W   EE+L  +LV+ K+YK +   +    LDT   E L ++   FE+   KLL+  +  D E A  ++  E  +W   +CL +A  A  +  ++    Q  L   W  G     N N F+ IL + +PF I +  F                      DN                +Y + ++K            DT+    F N   +       PL+L     +FY AP TKF   S+A+   +  FS+ VL  M++M     E   I Y+  +  EK  E+   +   +  +   W WN   WN  D   +IL  + +  RF    +    DI  +  C  +I      Y+YLR L ++ V+K LGP + M+ KM+  ++++++++ ++L+++G++ Q   +P +  + + +  +   PY+ ++GE+
Sbjct:   27 KHQPRSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKL---AVLNNRHAYFLLVDNGTQAKYGAELI--LRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF-------VHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQEL---LQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSP-------PEQLSLALTWNRVDIARSEIF--VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNM--WNPCDGAAIILFVIGLAFRF----RENTMDIGRVIYCVDSI------YWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 1026

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339079)

HSP 1 Score: 263.077 bits (671), Expect = 7.576e-71
Identity = 278/1048 (26.53%), Postives = 456/1048 (43.51%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK-DKIPYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFV-KNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQ---RTKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDG--VPMLPEM--YRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED-----HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL--FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFN----LKRTIFHFLGRNFSNGLGDVKDLLTKIFG-----YYEDQ-------------CAMCDEEIIH-----------------------------PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSP---LDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF----NINLFQCILCIFLPFLIYRRSF----------------------DN----------------SYVIHESK---------KKDDTSNKGYFTNSGNW-------PLKL----VQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYW-WNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            + +I+  F   +C  F+   K+     TKC CG+ +  H+    I      D W         PT+++G IEF G    +    ++VRLS +   + +++L    WN+E+  L I+V GG  NF ++ K K    +GL+KA KTT A I T G N G+T+ VGDA+      L +  +    +  +GIAPWG V +N ++L H +        S    L     LN  H ++L VD   +  Y        R  LEK +S            PVV L+IEG  +      + + ++  VP+V+C G+GRA+DLL  AF       + +   DG   P+L  M  Y     +K  +  +   +K+ + L    +    + LIT+F ++E       +L+  IL +L K    +          QLSL L WNRVDIA+ +IF  V      N AL   + +++ + + +FV+L L+NG  M  FLT   LE+LY       N    + R +   + + +   L D+  ++ K+ G     YY  +                C +   +                             PF EL IW+VL +  + A   W   EE+L  +LV+ K+YK +   +    LDT   E L ++   FE+   KLL+  +  D E A  ++  E  +W   +CL +A  A  +  ++    Q  L   W  G     N N F+ IL + +PF I +  F                      DN                +Y + ++K            DT+    F N   +       PL+L     +FY AP TKF   S+A+   +  FS+ VL  M++M     E   I Y+  +  EK  E+   +   +  +   W WN   WN  D   +IL  + +  RF    +    DI  +  C  +I      Y+YLR L ++ V+K LGP + M+ KM+  ++++++++ ++L+++G++ Q   +P +  + + +  +   PY+ ++GE+
Sbjct:   20 RSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKL---AVLNNRHAYFLLVDNGTQAKYGAELI--LRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF-------VHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQEL---LQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSP-------PEQLSLALTWNRVDIARSEIF--VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNM--WNPCDGAAIILFVIGLAFRF----RENTMDIGRVIYCVDSI------YWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 1015

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Match: Trpm (gene:FBgn0265194 transcript:FBtr0339077)

HSP 1 Score: 263.077 bits (671), Expect = 9.314e-71
Identity = 280/1053 (26.59%), Postives = 460/1053 (43.68%), Query Frame = 3

Query:  240 EKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK-DKIPYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFV-KNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQ---RTKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDG--VPMLPEM--YRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED-----HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL--FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFN----LKRTIFHFLGRNFSNGLGDVKDLLTKIFG-----YYEDQ-------------CAMCDEEIIH-----------------------------PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSP---LDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF----NINLFQCILCIFLPFLIYRRSF----------------------DN----------------SYVIHESK---------KKDDTSNKGYFTNSGNW-------PLKL----VQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYW-WNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            +++  + +I+  F   +C  F+   K+     TKC CG+ +  H+    I      D W         PT+++G IEF G    +    ++VRLS +   + +++L    WN+E+  L I+V GG  NF ++ K K    +GL+KA KTT A I T G N G+T+ VGDA+      L +  +    +  +GIAPWG V +N ++L H +        S    L     LN  H ++L VD   +  Y        R  LEK +S            PVV L+IEG  +      + + ++  VP+V+C G+GRA+DLL  AF  + KY       DG   P+L  M  Y     +K  +  +   +K+ + L    +    + LIT+F ++E       +L+  IL +L K    +          QLSL L WNRVDIA+ +IF  V      N AL   + +++ + + +FV+L L+NG  M  FLT   LE+LY       N    + R +   + + +   L D+  ++ K+ G     YY  +                C +   +                             PF EL IW+VL +  + A   W   EE+L  +LV+ K+YK +   +    LDT   E L ++   FE+   KLL+  +  D E A  ++  E  +W   +CL +A  A  +  ++    Q  L   W  G     N N F+ IL + +PF I +  F                      DN                +Y + ++K            DT+    F N   +       PL+L     +FY AP TKF   S+A+   +  FS+ VL  M++M     E   I Y+  +  EK  E+   +   +  +   W WN   WN  D   +IL  + +  RF    +    DI  +  C  +I      Y+YLR L ++ V+K LGP + M+ KM+  ++++++++ ++L+++G++ Q   +P +  + + +  +   PY+ ++GE+
Sbjct:  110 KEHQPRSWIETNFQKRECIKFIPCPKD----DTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQGG--AHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDAL------LLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKL---AVLNNRHAYFLLVDNGTQAKYGAELI--LRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLL--AF--VHKY-----ASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQEL---LQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSP-------PEQLSLALTWNRVDIARSEIF--VYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLGYILRDVRPHIPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYANACRKSSTYQYQRYAGANSLSLVTGLLPFTSEMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTN-FKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMP-RWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNM--WNPCDGAAIILFVIGLAFRF----RENTMDIGRVIYCVDSI------YWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEV 1110

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:NCBI gene;Acc:799412])

HSP 1 Score: 280.411 bits (716), Expect = 1.924e-76
Identity = 262/1010 (25.94%), Postives = 460/1010 (45.54%), Query Frame = 3

Query:  219 VNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKI-PYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGN--NSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRT-KNKEP---IPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVN--EALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFL-TTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNG-----------LGDVKDLLTKIFGYYEDQCAM------------------------CDEE------IIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIET-LSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNIN--LFQCILC-IFLP-----FLIYRRSFD---------------NSYVIHESKKKDDTSNKGYFTNSGNWPL----KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDY-PYWAIFGEITLN 2999
            ++ + + ++  L  +IK+     +C F+VE  +E       C CG  K +H  + I P + + + W  H      PT++FG I F G      K  ++VR+S + + +++ +LM + W +    L ISV GG KNF +K   K  F +GLIK  +TT A ILT G + G+ + VG A+++     Y  + G+    +  +G+APWG + N+  L H +G    Y   +E        L+ NHTH+L VD+  +  Y      + R  LEK +S+ +  N+E    IPVV ++++G           +  + P V+  G+GR +D++      +   P+ ++    +        N L K+   +   N  ++   E    I++I+   +L+T+F + ED  +D+++AIL +L+K       +  +    QL L + WNRVDIA+ +IF+     +  +    +  +++  K EFV L L+NG  + +FL    TL +LY   P  F L++      G     G           L  V + +  + G +     +                        C  E      +  P ++LF+W+V+  N E A   WE+  + +  AL A+KI + L + S  D S   T +    +++E  AI +  ECH  D + A  ++ + + +WG  TCL +A +A D+ FI+    Q  L   W    +++   ++ +LC IF P     FL +RR  D                S    +S  K     +G+   S   PL    +L+ F  +PQ KF  +  ++   ++ F+ V++   +    +  E+L  ++L  +  E+  +++         R    +  + WN +D+L ++L    +I R          D V  +   K I  +    F LR + + S+ + LGPKI+++ +M+  L F++ ++ I ++AYG+  QG    + +  LN +     Y PY  IFG    N
Sbjct:   25 LSLSPSFQRCSLASWIKENIKKKECCFYVEDGRE-----GICKCGYPKVQHCDEAIKPEDYMGEQWDKHRHVRETPTDAFGDISFGG---LGQKTGKYVRVSSDTSCENLYQLMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAVRD-----YTLSSGSMEGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDGTQGHYGVE--IELRARLEKLISKLSLGNRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIA----HVASVPVSKVTMALI--------NRLLKRFFMQEYKNFTELQIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEESQWTSSDLHPAMFSALVGDKPEFVRLLLENGVCVREFLEREETLCELYSHLPSCFFLRKLAKRVQGGKMRRGQEPLPGSRKVCLSHVSEEVRHLLGSFTQPLYIASRYKPTKDDVRLKVPSKGALDLPCSGEEWSADTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQESGEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYTGFLTFRRDEDIQRQAERTEQQKLAMESVFAGQSDGKIKRHLRGFSQKSELKPLNCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQ-TSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQ------ASDTV--FYIGKVILCIDFIIFCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILI-ENEERLNWIIRGAVYEPYITIFGNFPTN 997

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:ZFIN;Acc:ZDB-GENE-060531-95])

HSP 1 Score: 260.766 bits (665), Expect = 4.669e-70
Identity = 214/747 (28.65%), Postives = 354/747 (47.39%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH-------------KKDKIPYNKV--NDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYK-VSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-FLKESIING----KYEFVELFLQNGAVMNDFLTTTTLEK-----------LYE--------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED------------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTW 2204
            K +I++ F   +C   +  +K+      +C CG L  +H             K +++P N      WSI    +  PT++FG IEF G   +N  +  +VR+S++   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   K  +  Y+ +SN   L++   LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L    +  ++  I          + E  R+ L   +      +  +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +  L++S+++     + +FV+L ++NG  M+ FLT + LE+           LY         + P  + +                          RT++H       N  G  +    K+ G  +D                     + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N ++ F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W
Sbjct:    3 KSWIERAFSKRECVHIIVSTKD----HHRCCCGRLIGQHVGLPPSISSNQNEKSERVPKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSYDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDLV-GKDVVRPYQTMSNP--LSKLTVLNSLHSHFILADNGTTGKYG--AEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGI----------INESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQSMLDALVLDRVDFVKLLIENGVSMHRFLTLSRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNQNSRE-FGQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMW 702

HSP 2 Score: 73.9442 bits (180), Expect = 1.417e-12
Identity = 53/170 (31.18%), Postives = 93/170 (54.71%), Query Frame = 3

Query: 2496 HEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
             E + I Y+    IEK  E+   +  K+  ++K W     WN  D++ +++ ++ M+LR            +M Y   + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q    P  D S     NI   PYW I+GE+  +Q+
Sbjct:  913 QEWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQ-EYWNITDLMAILIFSIGMVLRL-------QDPPLMSY--GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPNEDPSWMLARNIFFMPYWMIYGEVFADQI 1072

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: hrc (histidine rich calcium binding protein [Source:ZFIN;Acc:ZDB-GENE-041008-189])

HSP 1 Score: 244.202 bits (622), Expect = 2.497e-65
Identity = 241/961 (25.08%), Postives = 424/961 (44.12%), Query Frame = 3

Query:  258 GFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK----DKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTI-IKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASD--FREALEKKLS-QRTKNKE-PIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQK--YPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRN--------FSNGLGDVKDLLTKIFG------YYED----------------------QCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMS--PLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF--NINLFQCILCIFLP------FLIYRR---------------------------SFDNSYVIHESKKKDDTS--------------NKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQ---FTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISK 2831
             +I K F    C  FVE S     +   C CG ++ +H+     D      V+ W         PT+++G +EF G      + + F+RLS   +   V  LM ++W ++   L +SV+GG     +K   + +  QGL+KA ++T A I+T GL  GI+R VG+A+++    +   +   N +  +GIAPWG V+N++ L + +G+   +Y V N  +  +  SL+ NH  +L VD+      S  K  +  FR  LE  +S QR  N    IPV+ +LI G+  +       +K + P ++  G+G  ++L+ +    +Q    P      D  P++    R  L  K + K     +  ++ ++ +  I   + +I++++ K++   D E+ +L  L++          N+ + +L L + WNRVDIAK ++F+G +    E     + +++ N K +FV L + +G  +  +LT   LEKLY     +   K  + H L           +S  L +V  LLT + G      Y+ +                       C   DE   HP+  LFIW+VL    E A + WE  +ES+  AL   K+   L+E+S   ++T    ++      FE +A  +   C+ +    +  ++ +++  WG  TCLE+A  A+ Q F S    Q+ L   W         L++ +L I  P      F+ YR+                           SF+++   +E++ KD  +               K  F  S     +  QF+ AP T F  + L + + +F ++YV+L   K        + E +   ++  +  ++  E F    NK   +  + +  + WNK D+L + L    +  R    + +W+      +   + I  +    F LR + + ++HK LGPKI+++ K
Sbjct:   21 SWIPKFFKKRLCTTFVEDSFSYGGR---CQCGAMRDDHRSMALGDNFSTAVVSQWLSSQHTSEQPTDAYGDLEFDG---IGRRHSYFLRLSSTTDPARVFDLMKEHWKLQQPNLVVSVVGGEGRSVVKSWVRDVLRQGLVKAAQSTGAWIITGGLRQGISRCVGEAVKDNAAAV--SSITLNKVLPIGIAPWGLVENRQQLVNLEGSFPARYMVRN--ISPDSCSLDNNHKAFLLVDD----GTSGRKGGELAFRACLEDYISRQRPGNASIDIPVLNMLIAGDTSMLEFLEMSLKNSTPCLVLAGSGGLANLVSDIVENVQSAAMPGASEEEDASPIME--LREQLAAK-VKKYFPAENDTDKLVDKVLSIYQNKDIISIYNAKQEGAEDFEIVMLKVLVQASKRNVSENTNSYADELRLAVTWNRVDIAKSELFNGNIDWKYEELVDSMTDALENNKPQFVRLLIDSGLNILSYLTYGRLEKLYNSISDTCLAKTLLLHHLDERMHESNVQIYSISLYEVSQLLTDLLGEVCHPFYWTELKLEASSTRRKSMKKACRILMGSCKYRDEMCKHPWFCLFIWAVLQNRSEMAIFCWEMCDESVLTALAGCKL---LLELSKQEIETEAKLSMKELALKFERMAHDVFGTCYLSKASHSYKLLIRKSKLWGDATCLEMAIAADAQIFFSHDGVQSLLSQIWWGDIERGTPLWRILLVIICPPVCYSNFIEYRKTDQAEKEKSVMAPPCSEIDRQYEETVFSFNDNKHQNEAEHKDSENIRRTAKGAPAFIKPKKSSFVVS-----RWKQFWYAPVTSFIGNLLMYFLFLFLYAYVLLVDFKPPPPDGPAVSEYVLYFWVFTLVCQEIQEAF-IAGNKKFPQTLFLYAQDVWNKFDVLAISLFITGLCCR----MFSWS------FNMGRGILCVDYMVFTLRLIYIFAIHKELGPKIIILGK 945

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: trpm4b.2 (transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-061214-2])

HSP 1 Score: 238.81 bits (608), Expect = 1.314e-63
Identity = 247/1011 (24.43%), Postives = 448/1011 (44.31%), Query Frame = 3

Query:  261 FIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK----DKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLS-QRTKNKE-PIPVVLLLIEGEYDV--FFEASKRIKENVPIVICVGTGRASDLLGEAFREMQK--YPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSN--------GLGDVKDLLTKIFG-----YYEDQ----------------------CAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMS--PLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF--NINLFQCILCIFLPFLIYRRSF----------------------DNSY---------VIHESKKKDDTSNKGYFTNSGNWPL-----------KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQ---FTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            F KK+     C  FVE S   SN    C CG  +  H      D      V+ W         PT+++G+++F   + +  + + F+RLS   +   V  LM ++W ++   L +SV+GG    ++K     I  QGL+K  ++T A I+T GL  GI+R +G+A+++    +   +   N +  +GIAPWG V+N++ L +++G+    KV+ +    +  +L+ NH  +L VD+          A  FR  LE  +S QR  N    IPV+ +LI G+  +  F E S  +K + P ++  G+G  ++L+ +    +Q    P    + D  P++    R  L  K + K      K ++ ++ +  I   + +I++++ +++   D ++ +L  L++          N+ + +L L + WNRVDIAK ++F+G +    E     + +++ N K +FV L + NG  ++ +LT   LE LY     +   K  + H L               L +V  LLT +FG     +Y+ +                      C   DE+  HP+  LFIW+VL    E A +FWE   ES+  AL   K+   L+E+S   ++T    ++      FE +A  +   C+      +  ++ +++  WG  TCL++A  A+ + F S    Q+ L   W          ++ +L +  P L Y                          D+ Y         + H+++ +++ SN       G               +  QF+ AP T F  + L + + +F ++YV+L   K        + E +   ++  +  E+  E      NK   ++ + +  + WNK D+L + L    +  R    + +W+      +   + I  +    F LR + + ++H+ LGPKI+++ KM+    F++  +L+ L AYG+  Q   +        T   ++  PY  IFG+I + ++
Sbjct:   24 FFKKRL----CTTFVEDS--FSNGGL-CQCGAARDHHPSVALGDNFSTAVVSQWFSTQHSSEQPTDAYGELDF---NNSRKRDSYFLRLSSTTDPAKVFDLMKEHWKLQQPNLVVSVVGGEGRSEVKSWVLDILRQGLVKTAQSTGAWIITGGLRQGISRCIGEAVKDNATAV--SSITLNKVLPIGIAPWGLVENRQHLVNSEGSF-PAKVTTQ----DSCNLDNNHKAFLLVDDGTTGRKGGELA--FRARLEDYISRQRPGNASIDIPVLNMLIAGDTSMLEFLEMS--LKNSTPCLVLAGSGGLANLVSDIVENVQSAAMPGASEKEDASPIME--LREQLAAK-VKKYFPAEKKTDKLVDKVLSIYQNKDIISIYNAEQEGAEDFDIVMLKVLVQASKRNVSENTNSYADELRLAVTWNRVDIAKSELFNGHIDWKYEELKDSMTDALENNKPQFVRLLIDNGLNISTYLTYNRLEILYNSISDTCLAKTLLLHHLNERIHQSIKQIYKISLYEVSQLLTDLFGEVCLPFYKAELKLEATTKRKALKNACDVLNGSCTYRDEKCKHPWLCLFIWAVLQNRREMAIFFWEMCGESVLTALAGCKL---LLELSKQEIETEAKLSMKELALKFEQMAHDVFGTCYQTKASHSYKLLIRKSKLWGDATCLKMAIAADARIFFSHDGVQSLLSQIWWGDIERGTAFWRLLLVMICPPLCYTNCIEFRKTDPAKEEKSMTAPPSSPTDSHYEKTVYSFKDIKHQNEGENEDSNHIRQNTKGEPAFIESMKSSFVVSRWKQFWYAPVTSFIGNLLMYFLFLFLYAYVLLVDFKPPPPDGPAVSEYVLYFWVFTLVCEEIREA-SIAGNKKFPQMLFVYAQDMWNKFDVLAISLFITGLCCR----MFSWS------FNMGRGILCVDYMVFTLRLIHIFAIHRQLGPKIIILGKMIKDAFFFLFFLLVWLSAYGVANQALLYQYDPSPARTFRRVLYRPYLHIFGQIPVEEI 996

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Match: trpm5 (transient receptor potential cation channel, subfamily M, member 5 [Source:ZFIN;Acc:ZDB-GENE-060503-736])

HSP 1 Score: 228.794 bits (582), Expect = 1.444e-60
Identity = 182/654 (27.83%), Postives = 304/654 (46.48%), Query Frame = 3

Query:  450 FGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLS-QRT----KNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAF-REMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSF-NLKRTIF-------------HFLGRNFSNGLGD-------------VKDLLTKIF-GYYEDQCAMC-----------DEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF--NINLFQCILCIFLPFLIY 2270
             G I+F G   T  K   FVR++   +  ++ +++   W +    L ++++GG +  ++K   +    +GL+KA ++T A ILTSGL  GIT+ +G A+++              +  +GIAPW  ++N+ +L  AK        + ++      SL+ NH+H++ VDE  +         + R  + K +S QRT         IPV+ LL+ GE  +  +  K I+ ++P +I  G+G  +D+L     R      I Q          E+  N+    L    +++  K+      I+ I+   +L+T+ D ++D +L+  IL +L+K     S    + L  +L L + WNRVDIAK +IFSG V  S ++    + E+++N K +FV LF+ NG  +  FLT   L++LY  C  S  NL  T+                +  N +N LGD             +KD L     G+Y+   A+            D    HP+++LF+W++L    E ANYFW    E++  ALV  KI K   EM+ L T      S     +E  A+ L  EC+   ++ A  ++ ++   W   T L IA  AE + F +    Q  L   W      + ++ + +L  F+P L++
Sbjct:   17 LGDIDFTGVSRTRGK---FVRVTSSTDPAEIYQILTKQWGLAPPHLVVALMGGDEVAQLKPWLRDTLRKGLVKAAQSTGAWILTSGLRFGITKNLGQAVRDHSLA---STSPKVRVVAIGIAPWNMIQNRDLLLSAKPDHPATYPTEDLPYGAVYSLDCNHSHFILVDEDPK---RPGATGEMRVKMLKHISLQRTGYGGTGSIEIPVLCLLVHGEPRILQKMYKNIQNSIPWLILAGSGGVADILVTLMDRGCWDADIVQ----------ELLINTFPDGLHSTEITSWTKL------IQRILDHGHLLTVHDPEQDSELDTVILKALVKACKSQSQEAQDFLD-ELKLAVAWNRVDIAKSEIFSGDVQWSAQDLEEVMMEALVNDKPDFVRLFVDNGVNIKQFLTYGRLQELY--CSVSEKNLLHTLLLKKNQERQAQLARKRMSGNPNNELGDRKFRFTFHEVSKVLKDFLDDTCKGFYQKLPAVSKALHQKNLPDMDRRCEHPWRDLFLWAILQNRQEMANYFWAMGPEAVAAALVGCKIMK---EMAHLATEAESARSMKNAKYEQFAMDLFSECYSNSEDRAYSLLVRKTCCWSKATVLNIATLAEAKCFFAHDGVQALLTKVWWGAMRTDTSISRLVLTFFIPPLVW 639

HSP 2 Score: 52.7582 bits (125), Expect = 3.280e-6
Identity = 36/132 (27.27%), Postives = 66/132 (50.00%), Query Frame = 3

Query: 2610 NNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            +NWNK D++ + L  + +  R  +            Y   +T+ +L    F LR + + ++HK LGPKI+++ +M+  + F++  + + L+AYG+T Q    P            +  PY  IFG+I L ++
Sbjct:  786 DNWNKCDMVAISLFVVGLSCRMAM----------STYEAGRTVLALDFMVFTLRLIHIFAIHKQLGPKIIIVERMIKDVFFFLFFLSVWLIAYGVTTQALLHPNDPRIDWVFRRALYRPYLHIFGQIPLEEI 907

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: aldh3a2 (aldehyde dehydrogenase 3 family member A2 [Source:Xenbase;Acc:XB-GENE-942662])

HSP 1 Score: 324.324 bits (830), Expect = 3.079e-90
Identity = 301/1052 (28.61%), Postives = 493/1052 (46.86%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH----------KKDKIPYNKVND-----WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKI--------FSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-------------------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED-----------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN----SYVIHES-----KKKDDTSNKGYFTNSGNW-----------------PL--KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ FH  +C   +  +K+      +C CG L  +H          + +K      ND     WSI    +  PT++FG IEF G   +N  +  +VRLS +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGD+++    D   K++G   +C +GIAPWG V+N++ L   K  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++N  VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +I        FSG V  S E   L   ++++  + +FV+L ++NG  M+ FLT + LE+LY                    + P  + +                          RT++H       N  G  +    K+ G  +D                    + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N ++ F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N     Y+   +     +K+ +  +K      GN                  P+  K+ +FY AP  KF   ++A+   +  F+Y+VL  M R   ++ E + I Y+  + IEK  E+   +  K+  + K W     WN  D++ ++L ++ M+LR      +  G         + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S N   NI   PYW I+GE+  +Q+
Sbjct:   33 KSWIERAFHKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISIIQNEKNEGRHRNDIQSEKWSIGKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLK----DHASKSRGK--ICTIGIAPWGIVENQEDLV-GKDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIFIYGQQWPFSGRVG-SLEQAML---DALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDIPIRSGRKTTKKREEEIDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRE-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGILLPPSILSLEFKNKDEMPYMSQANEMDLQEKEVEEPDKTAMLARGNGDSSRKKDEDEHPRHRLIPIGRKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVKMDRWP-SMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQ-EYWNLADLVSILLFSIGMVLRLQEQPFSSYG---------RVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPSEEPSWNLAKNIFYMPYWMIYGEVFADQI 1022

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: TRPM1 (transient receptor potential cation channel subfamily M member 1 [Source:NCBI gene;Acc:100216447])

HSP 1 Score: 323.553 bits (828), Expect = 3.368e-90
Identity = 271/952 (28.47%), Postives = 468/952 (49.16%), Query Frame = 3

Query:  408 WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE---DCPRSF-----NLKRTIFHFLGRNFSNGLGDV---------------------KDLLTKIFGYYED------------------QCAMCDEEII---HPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLS-----NWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINL---FQCILCIFLP----FLIYRRSFDNSY-----------------VIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            WSI    +  PT++FG +EF G   +N  +  ++R+S++   D ++ LM   W +E+  L ISV GG +NF+M+ K K +F +GLIKA  TT A I T G++ G+ R VGDA++    D   K++G   +C +GIAPWG V+NK+ L     T     +SN   L++   LN +HTH++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + ++E   VP+V+C G+GRASD++  A +  ++  I          + E  R+ L   +      + ++ ++ L  + E + K+ LIT+F +  +   D+E+AIL +L+K  + ++         QLSL L WNRVDIA+ +IF         +    + ++++  + +FV+L ++NG  M  FLT   LE+LY      P +      ++K+  F  L  ++   L D+                     + L   +FG   D                     + D E+    +PF EL +W+VL++  + A + W++ EE++  ALVA K+YK +   S  ++  ++ +S     N KD F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +      + I+ I  P    FL +R   D S+                 V + + +K D  N      S     K+ +FY AP  KF  +++++   +  F+YV+L  M+R   ++ E + I Y++ + +EK  E+   +  K+  ++K W     WN  D++ + +  +  ILR             M Y   + IY + + ++Y+R L +  V+K LGP ++MI KM+  +++++IIML++L+++G+  Q    P  + S     NI   PYW I+GE+  +Q+
Sbjct:   20 WSISKHTQLSPTDAFGILEFQGGGHSNKAM--YIRVSYDSKPDSLLHLMVKEWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVIRHVGDALK----DHSSKSRGR--ICAIGIAPWGIVENKEDLIGKDVTKPYQTMSNP--LSKLSVLNSSHTHFILADNGTLGKY--GAEVKLRRQLEKHISLQKINTRLGQGVPVVALIVEGGPNVITIVLECLREEPPVPVVVCDGSGRASDIMSFAHKYSEEGGI----------ISESLRDQLLVTIQKTFNYSRNQAHQLLVVLMECMKKKELITVFRMGSEGQQDIEMAILTALLKGTNASA-------PDQLSLALAWNRVDIARSQIFVFGHHWPVSSLEQAMMDALVLDRVDFVKLLIENGVSMQRFLTIPRLEELYNTRLGPPNTLHYIVRDVKKVGFGNLPPDYHVSLIDIGLVLEYLMGGAYRCHYTRKTFRTLYNNLFGPKRDDEPPTKGKKKKKKKEEEIDMDVDDPEVSRFKYPFHELMVWAVLLKRQKMALFLWQRGEETMAKALVACKLYKSMAHESS-ESELVDDISQDLDNNSKD-FGQLALELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILFPPTILFLEFRSQDDLSFHTSKEYEEGKEKEDENMVRNTTSRKGDEENGNRKQKSIPIGTKIYEFYNAPIVKFWFYTISYLAYLMLFNYVILVKMERWP-SVQEWVVISYIVTLALEKVREILMSEPGKLSQKVKVWLQ-EYWNITDLVAISVFLIGAILRL-------QNQPYMGY--GRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVIIMLVVLMSFGVARQAILHPDEEPSWRLARNIFYMPYWMIYGEVFADQI 929

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: aldh3a2 (aldehyde dehydrogenase 3 family member A2 [Source:Xenbase;Acc:XB-GENE-942662])

HSP 1 Score: 322.013 bits (824), Expect = 1.673e-89
Identity = 300/1044 (28.74%), Postives = 487/1044 (46.65%), Query Frame = 3

Query:  267 KKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH----------KKDKIPYNKVND-----WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKI--------FSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-------------------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED-----------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN----SYVIH-------------------ESKKKD-DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            ++ FH  +C   +  +K+      +C CG L  +H          + +K      ND     WSI    +  PT++FG IEF G   +N  +  +VRLS +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGD+++    D   K++G   +C +GIAPWG V+N++ L   K  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++N  VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +I        FSG V  S E   L   ++++  + +FV+L ++NG  M+ FLT + LE+LY                    + P  + +                          RT++H       N  G  +    K+ G  +D                    + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N ++ F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N     Y+                      S+KKD D   +      G    K+ +FY AP  KF   ++A+   +  F+Y+VL  M R   ++ E + I Y+  + IEK  E+   +  K+  + K W     WN  D++ ++L ++ M+LR      +  G         + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S N   NI   PYW I+GE+  +Q+
Sbjct:    4 ERAFHKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISIIQNEKNEGRHRNDIQSEKWSIGKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLK----DHASKSRGK--ICTIGIAPWGIVENQEDLV-GKDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIFIYGQQWPFSGRVG-SLEQAML---DALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDIPIRSGRKTTKKREEEIDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRE-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGILLPPSILSLEFKNKDEMPYMSQANEMDLQEKEAMLARGNGDSSRKKDEDEHPRHRLIPIGR---KIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVKMDRWP-SMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQ-EYWNLADLVSILLFSIGMVLRLQEQPFSSYG---------RVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPSEEPSWNLAKNIFYMPYWMIYGEVFADQI 982

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: aldh3a2 (aldehyde dehydrogenase 3 family member A2 [Source:Xenbase;Acc:XB-GENE-942662])

HSP 1 Score: 321.242 bits (822), Expect = 3.445e-89
Identity = 299/1069 (27.97%), Postives = 495/1069 (46.30%), Query Frame = 3

Query:  207 KNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH----------KKDKIPYNKVND-----WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHF--------------LGRNFSNGLGDV---------------------KDLLTKIFGYYEDQCA------------------MCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN----SYVIHES-----------------KKKDDTSNKGYFTNSGNW-----------------PL--KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            + S     A  +    K +I++ FH  +C   +  +K+      +C CG L  +H          + +K      ND     WSI    +  PT++FG IEF G   +N  +  +VRLS +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGD+++    D   K++G   +C +GIAPWG V+N++ L   K  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++N  VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT + LE+LY       N   T++H               L  ++   L D+                     + L   +FG   D                     + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N ++ F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N     Y+   +                 +K++D          GN                  P+  K+ +FY AP  KF   ++A+   +  F+Y+VL  M R   ++ E + I Y+  + IEK  E+   +  K+  + K W     WN  D++ ++L ++ M+LR      +  G         + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S N   NI   PYW I+GE+  +Q+
Sbjct:   46 QGSTKRSGAAQQPTAQKSWIERAFHKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISIIQNEKNEGRHRNDIQSEKWSIGKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRLSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDSLK----DHASKSRGK--ICTIGIAPWGIVENQEDLV-GKDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDNPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSN---TLYHLVRDVKKVRVRHQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPIRSGRKTTKKREEEIDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRE-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSSLKVILGILLPPSILSLEFKNKDEMPYMSQANEMDLQEKEVEEPDKTVKEKEEDDMELTAMLARGNGDSSRKKDEDEHPRHRLIPIGRKIYEFYNAPIVKFWFFTMAYMGYLMLFNYIVLVKMDRWP-SMQEWIVISYIFTLGIEKMREILMSEPGKLLQKFKVWLQ-EYWNLADLVSILLFSIGMVLRLQEQPFSSYG---------RVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPSEEPSWNLAKNIFYMPYWMIYGEVFADQI 1055

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Match: TRPM1 (transient receptor potential cation channel subfamily M member 1 [Source:NCBI gene;Acc:100216447])

HSP 1 Score: 317.775 bits (813), Expect = 2.592e-88
Identity = 277/1018 (27.21%), Postives = 478/1018 (46.95%), Query Frame = 3

Query:  342 CLCGELKSEHKKDKIPYNKVND---------------WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEP----------------------IPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-------------------DCPRSFNLK---------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMC-----------------DEEII---HPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLS-----NWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINL---FQCILCIFLP----FLIYRRSFDNSY-----------------VIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            C CG+L ++H    +P N   +               WSI    +  PT++FG +EF G   +N  +  ++R+S++   D ++ LM   W +E+  L ISV GG +NF+M+ K K +F +GLIKA  TT A I T G++ G+ R VGDA++    D   K++G   +C +GIAPWG V+NK+ L     T     +SN   L++   LN +HTH++  D      Y        R  LEK +S +  N +                       +PVV L++EG  +V     + ++E   VP+V+C G+GRASD++  A +  ++  I          + E  R+ L   +      + ++ ++ L  + E + K+ LIT+F +  +   D+E+AIL +L+K  + ++         QLSL L WNRVDIA+ +IF         +    + ++++  + +FV+L ++NG  M  FLT   LE+LY                    + P  +++                      R  F  L   ++N  G  +    K+ G  +D+                     D E+    +PF EL +W+VL++  + A + W++ EE++  ALVA K+YK +   S  ++  ++ +S     N KD F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +      + I+ I  P    FL +R   D S+                 V + + +K D  N      S     K+ +FY AP  KF  +++++   +  F+YV+L  M+R   ++ E + I Y++ + +EK  E+   +  K+  ++K W     WN  D++ + +  +  ILR             M Y   + IY + + ++Y+R L +  V+K LGP ++MI KM+  +++++IIML++L+++G+  Q    P  + S     NI   PYW I+GE+  +Q+
Sbjct:    2 CCCGQLLTQHIP--VPQNATGNKNGEECKQLEAVPEKWSISKHTQLSPTDAFGILEFQGGGHSNKAM--YIRVSYDSKPDSLLHLMVKEWQLELPKLLISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVIRHVGDALK----DHSSKSRGR--ICAIGIAPWGIVENKEDLIGKDVTKPYQTMSNP--LSKLSVLNSSHTHFILADNGTLGKY--GAEVKLRRQLEKHISLQKINTQALIFFFAHNRLYYELKLICLGQGVPVVALIVEGGPNVITIVLECLREEPPVPVVVCDGSGRASDIMSFAHKYSEEGGI----------ISESLRDQLLVTIQKTFNYSRNQAHQLLVVLMECMKKKELITVFRMGSEGQQDIEMAILTALLKGTNASA-------PDQLSLALAWNRVDIARSQIFVFGHHWPVSSLEQAMMDALVLDRVDFVKLLIENGVSMQRFLTIPRLEELYNTRLGPPNTLHYIVRDVKKGNLPPDYHVSLIDIGLVLEYLMGGAYRCHYTRKTFRTL---YNNLFGPKRPKALKLLGMEDDEPPTKGKKKKKKKEEEIDMDVDDPEVSRFKYPFHELMVWAVLLKRQKMALFLWQRGEETMAKALVACKLYKSMAHESS-ESELVDDISQDLDNNSKD-FGQLALELLDQSYKHDEQVAMKLLTYELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLKVIMGILFPPTILFLEFRSQDDLSFHTSKEYEEGKEKEDENMVRNTTSRKGDEENGNRKQKSIPIGTKIYEFYNAPIVKFWFYTISYLAYLMLFNYVILVKMERWP-SVQEWVVISYIVTLALEKVREILMSEPGKLSQKVKVWLQ-EYWNITDLVAISVFLIGAILRL-------QNQPYMGY--GRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVIIMLVVLMSFGVARQAILHPDEEPSWRLARNIFYMPYWMIYGEVFADQI 972

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101])

HSP 1 Score: 324.324 bits (830), Expect = 2.471e-90
Identity = 297/1052 (28.23%), Postives = 493/1052 (46.86%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH--------------KKDKIPYNKVND--WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHF--------LGRNFSNGLGDV---------------------KDLLTKIFGYYEDQCAMC------------------DEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ F+  +C   +  +K+      +C CG L  +H               + ++  N +    WSI    +  PT++FG IEF G   +N  +  +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT + LE+LY       N   T++H         L  ++   L D+                     + L   +FG   D   +                   D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  ++      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:   62 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSN---TLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 1051

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101])

HSP 1 Score: 323.939 bits (829), Expect = 3.625e-90
Identity = 297/1052 (28.23%), Postives = 493/1052 (46.86%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH--------------KKDKIPYNKVND--WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHF--------LGRNFSNGLGDV---------------------KDLLTKIFGYYEDQCAMC------------------DEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ F+  +C   +  +K+      +C CG L  +H               + ++  N +    WSI    +  PT++FG IEF G   +N  +  +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT + LE+LY       N   T++H         L  ++   L D+                     + L   +FG   D   +                   D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  ++      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:   64 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSN---TLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 1053

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101])

HSP 1 Score: 320.472 bits (820), Expect = 4.389e-89
Identity = 297/1066 (27.86%), Postives = 495/1066 (46.44%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH--------------KKDKIPYNKVND--WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-FLKESIING----KYEFVELFLQNGAVMNDFLTTTTLEKLYE-------------------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED-----------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ F+  +C   +  +K+      +C CG L  +H               + ++  N +    WSI    +  PT++FG IEF G   +N  +  +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +  L++++++     + +FV+L ++NG  M+ FLT + LE+LY                    + P  + +                          RT++H       N  G  +    K+ G  +D                    + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  ++      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:   64 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 1063

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101])

HSP 1 Score: 320.472 bits (820), Expect = 4.400e-89
Identity = 297/1066 (27.86%), Postives = 495/1066 (46.44%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH--------------KKDKIPYNKVND--WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-FLKESIING----KYEFVELFLQNGAVMNDFLTTTTLEKLYE-------------------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED-----------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ F+  +C   +  +K+      +C CG L  +H               + ++  N +    WSI    +  PT++FG IEF G   +N  +  +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +  L++++++     + +FV+L ++NG  M+ FLT + LE+LY                    + P  + +                          RT++H       N  G  +    K+ G  +D                    + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  ++      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:   64 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 1063

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Match: Trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:MGI Symbol;Acc:MGI:2443101])

HSP 1 Score: 310.071 bits (793), Expect = 1.073e-85
Identity = 290/1045 (27.75%), Postives = 486/1045 (46.51%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH--------------KKDKIPYNKVND--WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRS----------FNLKRTIFHFLGRNFS-------------NGLGDVKDLLTKIFGYYED-----------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ F+  +C   +  +K+      +C CG L  +H               + ++  N +    WSI    +  PT++FG IEF G   +N  +  +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG        + TL  L  D  +            ++   I + +G  +              N  G  +    K+ G  +D                    + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  ++      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:   62 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGR----HGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMTQAQEIHLQEKEPEEPEKPTKEKDEEDMELTAMLGRSNGESSRKKDEEEVQSRHRLIPVGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 1043

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|Q9HCF6|TRPM3_HUMAN (Transient receptor potential cation channel subfamily M member 3 OS=Homo sapiens OX=9606 GN=TRPM3 PE=2 SV=4)

HSP 1 Score: 311.227 bits (796), Expect = 3.588e-85
Identity = 297/1091 (27.22%), Postives = 492/1091 (45.10%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH--------------KKDKIPYNKVND--WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNK----------------------------EPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-------------------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED-----------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN---------SYVIH---------------------------------ESKKKD--DTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ F+  +C   +  +K+      +C CG L  +H               + ++  N +    WSI    +  PT++FG IEF G   +N  +  +VR+S +   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   +  +  Y+      ++ P+S    LN  H+H++  D      Y        R  LEK +S +  N                             + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +         +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT + LE+LY                    + P  + +                          RT++H       N  G  +    K+ G  +D                    + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N +D F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL I LP  I    F N         +  IH                                  S+KKD  +  +K      G    K+ +FY AP  KF  ++LA+   +  F+Y+VL  M+R   T  E + I Y+  + IEK  E+   +  K+  ++K W     WN  D++ ++L ++ MILR  L  + +  D        + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q   FP  + S     NI   PYW I+GE+  +Q+
Sbjct:   62 KSWIERAFYKRECVHIIPSTKD----PHRCCCGRLIGQHVGLTPSISVLQNEKNESRLSRNDIQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSFDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDL-IGRDVVRPYQT-----MSNPMSKLTVLNSMHSHFILADNGTTGKY--GAEVKLRRQLEKHISLQKINTRCLPFFSLDSRLFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYTRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLTISRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRD-FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKDEEEVQSKHRLIPLGR---KIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST-QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKVWLQ-EYWNVTDLIAILLFSVGMILR--LQDQPFRSD-------GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIFYMPYWMIYGEVFADQI 1086

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|A7T1N0|TMP2L_NEMVE (Transient receptor potential cation channel subfamily M member-like 2 OS=Nematostella vectensis OX=45351 GN=TRPM2 PE=1 SV=1)

HSP 1 Score: 299.286 bits (765), Expect = 1.663e-81
Identity = 207/743 (27.86%), Postives = 366/743 (49.26%), Query Frame = 3

Query:  192 LTDGSKNSNVN---FNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFV-KNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKA--SDFREALEK-KLSQRTKNKE-PIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLF--DVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLK------------RTI-FHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEII---------------------HPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDY---FENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRA--GFNINLFQCILCIFLPFLIY 2270
            L DG  +S+V+   F +N      K +I + F   +C  FV KS ++S    +C CG  +  H +  +   + ++ W++ SC    PT ++G+I+F  E     K   ++R+SH+ + + V+ LM   WN+EI  L ISV GG K+F +K + + +F +GLIKA KTT A I+T G N G+ + VG+A++  Q       + N     +GIA WG V K   ++    G              +   L+ NH+H+  VD+     Y       S   EA+ K K   R++     +PVVLL++EG  +      + IK+ VP V+  G+GRA+ ++G A+    K   + +    + ++   Y + ++ K+++  V      ++  + I++++  E +I+++  D +   D++LAIL +L+K       +  ++  +QL+L L WNR+D+AK  IF+     + E  +  +  ++++ K EF ELFLQNG  M +FL+   L KLY + P +  +K            +TI    +G      +GD+ +   +  G+Y  + A   E ++                      P+ ++F+W+VL    E A   WE   E +  AL+A+++ K +   +  D +  +  S+  D+   FE  A+ +L+EC + ++  +  ++ +E   +   T LE+A  AE Q FI+   CQ  L   W      N   ++ ++C++LP LI+
Sbjct:    9 LYDGGDSSHVHLNKFGSNQLSQSKKSWIARNFSRRECIRFVPKSHDVS----RCKCGRPRERHSQQALESGQGSEEWNVASCTTKHPTNAYGEIDF--EGYGGQKRAPYLRMSHDTDANLVITLMLKRWNLEIPNLVISVTGGAKSFVLKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDTQVN----VIGIATWGIVDKQSDLISEKNGKYPALYSMEPTPGHQGAMLDPNHSHFFLVDDGTEGKYGVEIGMRSRIEEAIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKKVPAVVIDGSGRAASVVGFAYNHTIK---RNVDGQTINVIDPQYEDEVRAKVVE--VFGAKGADKTYSMIKDVLEDEKMISVYSLDGEISQDIDLAILKALLK-------ANRSSPVAQLNLALAWNRIDLAKSDIFTEEQQWTTETLSAAMLTALLDDKAEFAELFLQNGLSMREFLSLDILCKLYAEVPGNTTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYYRKDGHYFGELASYAEGLVLKNRKSSKDLLANINRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRAQEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRWWKVLVCLYLPVLIF 729

HSP 2 Score: 73.559 bits (179), Expect = 1.183e-11
Identity = 54/174 (31.03%), Postives = 100/174 (57.47%), Query Frame = 3

Query: 2499 EILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQ-----RDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            EI+   ++  + IE+  ++       + D++  +++ + WN VDI  + +  +A+ILRF     N       I+  S+ I SL + +F +R L++ SV++ LGPK+VMI KM+  L  +III+ +  +AYGI +    FP      R+ +  T+ +++ YPYW ++GE+ L+++
Sbjct:  879 EIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFS-DTWNFVDIFSLTVFIIAIILRF---FTN-----SRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGELFLDEI 1043

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|A0A0R4IMY7|TRPM2_DANRE (Transient receptor potential cation channel subfamily M member 2 OS=Danio rerio OX=7955 GN=trpm2 PE=1 SV=2)

HSP 1 Score: 280.411 bits (716), Expect = 1.452e-75
Identity = 262/1010 (25.94%), Postives = 460/1010 (45.54%), Query Frame = 3

Query:  219 VNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKI-PYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGN--NSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRT-KNKEP---IPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVN--EALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFL-TTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNG-----------LGDVKDLLTKIFGYYEDQCAM------------------------CDEE------IIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIET-LSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNIN--LFQCILC-IFLP-----FLIYRRSFD---------------NSYVIHESKKKDDTSNKGYFTNSGNWPL----KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDY-PYWAIFGEITLN 2999
            ++ + + ++  L  +IK+     +C F+VE  +E       C CG  K +H  + I P + + + W  H      PT++FG I F G      K  ++VR+S + + +++ +LM + W +    L ISV GG KNF +K   K  F +GLIK  +TT A ILT G + G+ + VG A+++     Y  + G+    +  +G+APWG + N+  L H +G    Y   +E        L+ NHTH+L VD+  +  Y      + R  LEK +S+ +  N+E    IPVV ++++G           +  + P V+  G+GR +D++      +   P+ ++    +        N L K+   +   N  ++   E    I++I+   +L+T+F + ED  +D+++AIL +L+K       +  +    QL L + WNRVDIA+ +IF+     +  +    +  +++  K EFV L L+NG  + +FL    TL +LY   P  F L++      G     G           L  V + +  + G +     +                        C  E      +  P ++LF+W+V+  N E A   WE+  + +  AL A+KI + L + S  D S   T +    +++E  AI +  ECH  D + A  ++ + + +WG  TCL +A +A D+ FI+    Q  L   W    +++   ++ +LC IF P     FL +RR  D                S    +S  K     +G+   S   PL    +L+ F  +PQ KF  +  ++   ++ F+ V++   +    +  E+L  ++L  +  E+  +++         R    +  + WN +D+L ++L    +I R          D V  +   K I  +    F LR + + S+ + LGPKI+++ +M+  L F++ ++ I ++AYG+  QG    + +  LN +     Y PY  IFG    N
Sbjct:   25 LSLSPSFQRCSLASWIKENIKKKECCFYVEDGRE-----GICKCGYPKVQHCDEAIKPEDYMGEQWDKHRHVRETPTDAFGDISFGG---LGQKTGKYVRVSSDTSCENLYQLMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWILTGGTHAGVMKHVGMAVRD-----YTLSSGSMEGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYSLDEQGQGRLSCLDINHTHFLLVDDGTQGHYGVE--IELRARLEKLISKLSLGNRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIA----HVASVPVSKVTMALI--------NRLLKRFFMQEYKNFTELQIIEWTKKIQDILRMPHLLTVFRIDEDKNYDVDVAILQALLKASRSDEHAGRHCWERQLELAVAWNRVDIAESEIFTEESQWTSSDLHPAMFSALVGDKPEFVRLLLENGVCVREFLEREETLCELYSHLPSCFFLRKLAKRVQGGKMRRGQEPLPGSRKVCLSHVSEEVRHLLGSFTQPLYIASRYKPTKDDVRLKVPSKGALDLPCSGEEWSADTVWDPGRDLFLWAVVQNNRELAEIGWEQCRDCIAAALAASKILRKLAQESGEDDSEEATEMLELANHYEKQAIGVFSECHSWDAQRAQKLLIRISPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYTGFLTFRRDEDIQRQAERTEQQKLAMESVFAGQSDGKIKRHLRGFSQKSELKPLNCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVVLMIDFQ-TSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKDLWNILDVLSIVLFIAGLICRLQ------ASDTV--FYIGKVILCIDFIIFCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVVAYGVAKQGILI-ENEERLNWIIRGAVYEPYITIFGNFPTN 997

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|Q91YD4|TRPM2_MOUSE (Transient receptor potential cation channel subfamily M member 2 OS=Mus musculus OX=10090 GN=Trpm2 PE=1 SV=2)

HSP 1 Score: 266.929 bits (681), Expect = 2.781e-71
Identity = 236/923 (25.57%), Postives = 422/923 (45.72%), Query Frame = 3

Query:  231 ANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKI-PYN-KVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKE----PIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGE-AFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRS--FNLK------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYE-DQCAMCDEEI-----------------------IHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNIN--LFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVG-DRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISK 2831
            +++++ +L  +I +     +C +FVE SK     +  C CG    +H +  I P+  +  +W      + +PT++FG I F   D++  K+ ++VR+S +     + +LM  +W +++  L ISV GG KNF MK + K IF +GL+K  +TT A I+T G + G+ + VG+A+++    L    K    +  +G+A WG + N++ L H  G      + +E        L+ NH+H++ VD+     Y        R  LEK +S++TK +      IP+V +++EG           I    P VI  G+GR +D++ + A   + +  I  ++        EM+    + +++           E    I++I+ +  L+T+F   +D   D+++AIL +L+K               QL L + WNRVDIA+ +IF+        +    +  ++I+ K EFV LFL+NG  + +F+T  TL  LYE+   S  F+ K                  R   H + +     LGD   LL     Y +  + +M    I                       I P ++L IW+V+  + E A   W ++++    AL  +KI K L +      S  E L+   D FE+ AI +  EC+  D+E A  ++ + +  WG  TCL++A +A+D KF+S    Q  L   W     ++  L++ ILC+    L++       ++    K+                P ++  F+ AP   F ++ L++   +  F+YV++   +    +  E L  ++L  +  E+  ++F Y  +  G  ++   +  + WNK+D+  ++L  + +  R           I       + I SL    F LR + + ++ K LGPKI+++ +
Sbjct:   51 SSEKQENLSSWIPENIKKKECVYFVESSKLSDAGKVVCACGYTHEQHLEVAIKPHTFQGKEWDPKKHVQEMPTDAFGDIVFT--DLSQ-KVGKYVRVSQDTPSSVIYQLMTQHWGLDVPNLLISVTGGAKNFNMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRD--FSLSSSCK-EGEVITIGVATWGTIHNREGLIHPMGGFPAEYMLDEEGQGNLTCLDSNHSHFILVDDGTHGQYGVEIP--LRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAINNGTPCVIVEGSGRVADVIAQVATLPVSEITISLIQQKLSIFFQEMFETFTENQIV-----------EWTKKIQDIVRRRQLLTIFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEWQWKPADLHPMMTAALISNKPEFVRLFLENGVRLKEFVTWDTLLCLYENLEPSCLFHSKLQKVLAEEQRLAYASATPRLHMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSMTVPHIKLNVQGVSLRSLYKRSTGHVTFTIDPVRDLLIWAVIQNHRELAGIIWAQSQDCTAAALACSKILKELSKEEEDTDSSEEMLA-LADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLF-----TGFISFREKRLQALCR----------PARVRAFFNAPVVIFHMNILSYFAFLCLFAYVLMVDFQPSP-SWCEYLIYLWLFSLVCEETRQLF-YDPDGCGLMKMASLYFSDFWNKLDVGAILLFIVGLTCRL----------IPATLYPGRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKR 926

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Match: sp|E9PTA2|TRPM2_RAT (Transient receptor potential cation channel subfamily M member 2 OS=Rattus norvegicus OX=10116 GN=Trpm2 PE=1 SV=3)

HSP 1 Score: 266.544 bits (680), Expect = 3.992e-71
Identity = 236/927 (25.46%), Postives = 413/927 (44.55%), Query Frame = 3

Query:  231 ANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKI-PYN-KVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKE----PIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGE-AFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRS--FNLK-------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYE-DQCAMCDEEI-----------------------IHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNIN--LFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKF---CIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVG-DRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISK 2831
            +++++ +L  +I +     +C +FVE SK     +  C CG    +H +  I P+  +  +W        +PT++FG I F G    + K+ ++VRLS + +   + +LM  +W +++ +L ISV GG KNF MK + K IF +GL+K  +TT A I+T G + G+ + VG+A+++    L    K    +  +GIA WG + N++ L H  G      + +E        L+ NH+H++ VD+     Y        R  LEK +S++TK +      IP+V +++EG           I    P VI  G+GR +D++ + A   + +  I  ++        EM+    + +++           E    I++I+ +  L+T+F   +D   D+++AIL +L+K               QL L + WNRVDIA+ +IF+        +    +  ++I+ K EFV LFL+NG  + +F+T  TL  LYE+   S  F+ K                   R   H + +     LGD   LL     Y +  + ++    I                       I P ++L IW+++  + E A   W ++++    AL  +KI K L +      S  E L+   D FE+ AI +  EC+  D+E A  ++ + +  WG  TCL++A +A+D KF+S    Q  L   W     ++  L++ ILC+    L++       ++    K+              N P  +V FYL   + F   C+ +    V                  +  E L  ++L  +  E+  ++F Y  +  G  ++   +  + WNK+D+  ++L    +  R           I       + I SL    F LR + + ++ K LGPKI+++ +
Sbjct:   51 SSEKQENLSSWIPENIKKKECVYFVESSKLSDAGKVVCECGYTHEQHIEVAIKPHTFQGKEWDPKKHVHEMPTDAFGDIVFTG---LSQKVGKYVRLSQDTSSIVIYQLMTQHWGLDVPSLLISVTGGAKNFNMKLRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRD--FSLSSSCK-EGDVITIGIATWGTIHNREALIHPMGGFPAEYMLDEEGQGNLTCLDSNHSHFILVDDGTHGQYGVEIP--LRTKLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIYNAITNGTPCVIVEGSGRVADVIAQVAALPVSEITISLIQQKLSVFFQEMFETFTENQIV-----------EWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFTDEWQWKPSDLHPMMTAALISNKPEFVRLFLENGVRLKEFVTWDTLLCLYENLEPSCLFHSKLQKVLAEEHERLAYASETPRLQMHHVAQVLRELLGDSTQLLYPRPRYTDRPRLSLPMPHIKLNVQGVSLRSLYKRSTGHVTFTIDPVRDLLIWAIIQNHRELAGIIWAQSQDCTAAALACSKILKELSKEEEDTDSSEEMLA-LADEFEHRAIGVFTECYRKDEERAQKLLVRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLCVDNGLWRIILCMLAFPLLF-----TGFISFREKRLQALCRLARVRAFFNAP--VVIFYLNILSYFAFLCLFAYVLMVDFQPSP------------SWCEYLIYLWLFSLVCEETRQLF-YDPDGCGLMKMASLYFSDFWNKLDVGAILLFIAGLTCRL----------IPATLYPGRIILSLDFIMFCLRLMHIFTISKTLGPKIIIVKR 927

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: A0A5K4FE95 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 532.717 bits (1371), Expect = 2.321e-165
Identity = 361/1012 (35.67%), Postives = 555/1012 (54.84%), Query Frame = 3

Query:  228 NANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQT--KCLCGELKSEHKKDKIPYNKVN--DWSIHSCFETV-PTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNI---EIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKIL------EHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLS-QRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHF----------------------------LGRNFSNG----LGDVKDLLTKIFGYYEDQCAMCDEEIIH----------------PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPL-DTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIY---------RRSFDNSYVIHES----------KKKDDTSNKGYFTNSG---NWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGD-RIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQR-DFSLNTLPNIMDYPYWAIFGEITLN 2999
            +  D K     F+ K F   +C  FV   +  +  +   +C CGE +  H       ++ +  +WS   C + V P+ +FG+IEFI E  +N K TEFVR+S ED L+DVM LM +YW +   E  +LCISV+GG KNF ++  +K +FY GL++A +TT A I+TSGLNLGI R VGDA+Q  Q    DK   +  L C+GIAPWG+V N+  L      +H     I Y VS  I   +PVSLN+NHTHY+FVDE +R  Y   +++ FR  LEK+++         IPVVL+++EG +DVF +A   IKE VP+VIC GTGRA+D+L  AF         +L+ +      E   + L +KL  K VS  +KV  AL  I+ I+    LIT FD+ +  DL+LAIL++LIK    TS    + L  QL L L W+R DIA+ KIF     +  +     + E+++  K +FV + LQNG VM  FLT   L +LY +   S +L R + ++                             G++F++     L  +  L+ ++ G Y ++    D E++H                PFQELF+W++L + H+ A YFWE+++++L LAL+A  +Y  + ++ P  DT       ++ + FENLAI +LEEC+  D E   Y++E E+  WGG+ CL++A ++  +KFIS   CQNSLDF W  G   N+    + + LPFL+Y         +R   +    H++            ++D S+K    +     N+  K+  FY AP+TKFC++++ + + + +FSY +LF   + + TIHE   + Y I M I+   ++F   +  VG  ++  WW+   W + ++ +++L+ ++M LR  L       +   IY  SKT Y L +   Y+R   L S H NLGPK+VMI  ML +L+ +I I++++ LAYGI++    +P R +FS + + +++ YPYW ++GE++L+
Sbjct:   18 HVRDTKEKKISFVLKHFTFKECIKFVADPQYATETKPSDRCFCGEYRIYHYFHGQNRSETDNKEWSESECLKVVGPSNAFGQIEFITESTSNHKPTEFVRISDEDKLEDVMLLMKNYWKMMEPEKPSLCISVIGGAKNFVLEGHKKEVFYSGLVQAAQTTRAWIVTSGLNLGIIRVVGDALQE-QSYSTDKRMLSQQLRCIGIAPWGYVLNRNTLVATNYEDHFHP--IPYTVSTVIETGQPVSLNQNHTHYIFVDEGKRLRYGGCESARFRARLEKQIALPEEAGGFGIPVVLVIVEGGHDVFIDARNSIKERVPVVICSGTGRAADILDMAFN-------FRLKHNEFTSFTERECSILSQKL--KIVSGKNKVEAALKMIQLIVKDTKLITTFDMNKSDDLDLAILFALIK----TS----SELDKQLRLALTWDRCDIAEAKIFRQGKQVKPDILEPIMMEALLRNKTDFVRILLQNGVVMRQFLTFERLHRLYNESTHSNDLIRCLKNYKLLTSEHLTVSSTKLHLPVMISNEMTAERGQSFTSPYRIYLSTICKLIRRMLGRYTNKIYDMDTEVLHGRRADWSRVSKLTFVSPFQELFLWAILYQRHKMALYFWERSDDALTLALIACCLYTDMSKLLPTYDTEGKTKYESYVEEFENLAIGVLEECNAIDPEFTLYLVEGESSLWGGFNCLQLAAQSVRRKFISSQACQNSLDFAWCHGMRANMLVTSVILILPFLLYFDHILSWEDKRPHVSVNHHHQTVARFTENADVSDREDISHKNSKRSEPMQRNFTEKIKMFYTAPKTKFCLYTMVYVIFLLFFSYTLLFSTLQNEITIHEGFIMAYFIAMIIDIIRQIFL--SPGVGPKKVATWWDQYEWGRSELFVILLALLSMFLRIGL-------ETTFIY--SKTFYVLTLITCYIRIYGLYSYHPNLGPKLVMIRSMLEELISFIFILIVVFLAYGISLHVLLYPNRHEFSWSDVRDVLYYPYWNLYGELSLD 998

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: A0A267FX17 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017231g3 PE=4 SV=1)

HSP 1 Score: 525.398 bits (1352), Expect = 3.542e-159
Identity = 335/952 (35.19%), Postives = 525/952 (55.15%), Query Frame = 3

Query:  237 DEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNI---EIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKIL----EHAKGTI---IKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVS--NPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY-EDCPRSFNLKRTIFHFLG-----RN-FSNGLGDVKDLLTKIFGYYEDQC-------AMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLME-MSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF-----NINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITL 2996
            +++  L+ FI   F   +C  F  K  +      KC CGE++ +H    +P      W+  +      T ++G+I    E   N     F R+  ED++D +++LM  +W +   +  +LCISV+GG KNFK++ ++K +F+ GLI+A +TTNA I+TSGLNLGITR VG+A++ G+   ++K+  ++ L C+G+APWG+V N+  L    +   G +   ++YK+SN I   +PVSLN NHTHYL VD+ +R  Y  SK+   +  L+++++Q    KE I VVLL++EG  D+F E    I+ N+P+V C  TGRA+D++  A++++QK   K L    +  L E   ++  + L D      N  KV+E ++ + EI+ KE LIT+FD+    DL+LAIL +L+K MD     +L+    QL L + WNR DIA +KIF+       EN   F   +I   K EF+ LFL+NG +M +FLT   L  LY E    S      +   L      RN +   L D++ LL K+ G +              DE+   PF +LF W+VL+   + A + WE+T+ES+ LAL A+K+Y  +   +S  +  R   L  +KD FE+LA+ ++EEC   D   A  +IEK+   +G + CLE+A  A  +KF+SC   QNS+   W  G      N+ +F   LC+ LPFL+    F+    +  S + D+        +      K+  +Y AP TKF  +++ + + +F +S+ +LF MK    +  E + I ++  M +E+  EMF  K + V ++++ WW F+ WN++D+  ++L+ + + LR P            I    +T Y L    FYLR  RL   +  LGPK+VMI KM+ +L+FY+ I+++ LL YG+  Q   +P RDF+ +   +I+ YPYW I+GEI L
Sbjct:   75 EQQRSLRQFILANFQRKECCLFEAKDGK------KCACGEVREKHD-GLLPAGPEEKWNEATHMRRSVTNAYGRITLKNEGFDNRDPIHFARVCDEDSMDKMLELMKTHWQLADPQKPSLCISVIGGAKNFKLEGRKKEVFHHGLIRAAQTTNAWIITSGLNLGITRVVGNALEEGRASHWEKSSRSSKLRCIGVAPWGYVLNRDHLINKRDPKTGELSLDVEYKISNVISKGQPVSLNANHTHYLLVDDGKRNRYGGSKSGVIKAKLQEQINQ----KEGISVVLLIVEGGLDIFEETQSMIQSNIPVVTCDNTGRAADIIAFAYKKVQKADKKTLSESQLADLRERMISTFSENLKDPKTKKVNDKKVDENMSMLLEIVQKEKLITVFDMNRSDDLDLAILSALLKVMDA---KRLDDYKQQLQLSMTWNRPDIAAEKIFTEEHQWGTENLDKFALSAISQEKIEFLRLFLKNGLIMREFLTVGRLRSLYRESLAASSQASLQVRKLLAARTRCRNPWEPTLADIRVLLRKLVGKFHAPSMDKDVGTGGDDEQFERPFNQLFFWAVLLCKQDTAKFLWERTDESVPLALAASKVYNEMARALSSHEDGRKRMLQAYKDEFEDLAVHVVEECQMVDPSKAELLIEKKVEAFGDFNCLELAASANCKKFVSCNSSQNSITSRWLNGLMHGTSNLRIF---LCVVLPFLL---PFEFLVRVEPSVRLDEGGRCAQLAH------KVRIYYTAPVTKFFANAIWYVIFIFLYSWFILFEMKAASISWLEWVIIAWICVMVVEEIREMFSSKADTVQEKLRDWWGFSAWNRLDLFTMLLALIGIFLRIPEATD-------AITTGVRTCYILAGVLFYLRVFRLYYANSYLGPKLVMIQKMVKELLFYMSILIVALLTYGVAAQALLYPTRDFTTSIFVDIVYYPYWQIYGEIYL 993

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: A0A267E1J7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017231g2 PE=4 SV=1)

HSP 1 Score: 525.013 bits (1351), Expect = 5.511e-159
Identity = 335/952 (35.19%), Postives = 524/952 (55.04%), Query Frame = 3

Query:  237 DEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNI---EIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKIL----EHAKGTI---IKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVS--NPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY-EDCPRSFNLKRTIFHFLG-----RN-FSNGLGDVKDLLTKIFGYYEDQC-------AMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLME-MSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF-----NINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITL 2996
            +++  L+ FI   F   +C  F  K  +      KC CGE++ +H    +P      W+  +      T ++G+I    E   N     F R+  ED++D +++LM  +W +   +  +LCISV+GG KNFK++ ++K +F+ GLI+A +TTNA I+TSGLNLGITR VG+A++ G+   ++K+  ++ L C+G+APWG+V N+  L    +   G +   ++YK+SN I   +PVSLN NHTHYL VD+ +R  Y  SK+   +  L+++++Q    KE I VVLL++EG  D+F E    I+ N+P+V C  TGRA+D++  A++++QK   K L    +  L E   ++  + L D      N  KV+E ++ + EI+ KE LIT+FD+    DL+LAIL +L+K MD     +L+    QL L + WNR DIA +KIF+       EN   F   +I   K EF+ LFL+NG +M +FLT   L  LY E    S      +   L      RN +   L D++ LL K+ G +              DE+   PF +LF W+VL+   + A + WE+T+ES+ LAL A+K+Y  +   +S  +  R   L  +KD FE LA+ ++EEC   D   A  +IEK+   +G + CLE+A  A  +KF+SC   QNS+   W  G      N+ +F   LC+ LPFL+    F+    +  S + D+        +      K+  +Y AP TKF  +++ + + +F +S+ +LF MK    +  E + I ++  M +E+  EMF  K + V ++++ WW F+ WN++D+  ++L+ + + LR P            I    +T Y L    FYLR  RL   +  LGPK+VMI KM+ +L+FY+ I+++ LL YG+  Q   +P RDF+ +   +I+ YPYW I+GEI L
Sbjct:   75 EQQRSLRQFILANFQRKECCLFEAKDGK------KCACGEVREKHD-GLLPAGPEEKWNEATHMRRSVTNAYGRITLKNEGFDNRDPIHFARVCDEDSMDKMLELMKTHWQLADPQKPSLCISVIGGAKNFKLEGRKKEVFHHGLIRAAQTTNAWIITSGLNLGITRVVGNALEEGRASHWEKSSRSSKLRCIGVAPWGYVLNRDHLINKRDPKTGELSLDVEYKISNVISKGQPVSLNANHTHYLLVDDGKRNRYGGSKSGVIKAKLQEQINQ----KEGISVVLLIVEGGLDIFEETQSMIQSNIPVVTCDNTGRAADIIAFAYKKVQKADKKTLSESQLADLRERMISTFSENLKDPKTKKVNDKKVDENMSMLLEIVQKEKLITVFDMNRSDDLDLAILSALLKVMDA---KRLDDYKQQLQLSMTWNRPDIAAEKIFTEEHQWGTENLDKFALSAISQEKIEFLRLFLKNGLIMREFLTVGRLRSLYRESLAASSQASLQVRKLLAARTRCRNPWEPTLADIRVLLRKLVGKFHAPSMDKDVGTGGDDEQFERPFNQLFFWAVLLCKQDTAKFLWERTDESVPLALAASKVYNEMARALSSHEDGRKRMLQAYKDEFEELAVHVVEECQMVDPSKAELLIEKKVEAFGDFNCLELAASANCKKFVSCNSSQNSITSRWLNGLMHGTSNLRIF---LCVVLPFLL---PFEFLVRVEPSVRLDEGGRCAQLAH------KVRIYYTAPVTKFFANAIWYVIFIFLYSWFILFEMKAASISWLEWVIIAWICVMVVEEIREMFSSKADTVQEKLRDWWGFSAWNRLDLFTMLLALIGIFLRIPEATD-------AITTGVRTCYILAGVLFYLRVFRLYYANSYLGPKLVMIQKMVKELLFYMSILIVALLTYGVAAQALLYPTRDFTTSIFVDIVYYPYWQIYGEIYL 993

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: A0A267FD75 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017231g1 PE=4 SV=1)

HSP 1 Score: 523.472 bits (1347), Expect = 1.834e-158
Identity = 335/952 (35.19%), Postives = 522/952 (54.83%), Query Frame = 3

Query:  237 DEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNI---EIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTII-------KYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVS--NPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY-EDCPRSFNLKRTIFHFLG-----RN-FSNGLGDVKDLLTKIFGYYEDQC-------AMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLME-MSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGF-----NINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITL 2996
            +++  L+ FI   F   +C  F  K  +      KC CGE++ +H    +P      W+  +      T ++G+I    E   N     F R+  ED++D +++LM  +W +   +  +LCISV+GG KNFK++ ++K +F+ GLI+A +TTNA I+TSGLNLGITR VG+A++ G+   ++K+  ++ L C+G+APWG+V N+  L + +   I       +YK+SN I   +PVSLN NHTHYL VD+ +R  Y  SK+   +  L+++++Q    KE I VVLL++EG  D+F E    I+ N+P+V C  TGRA+D++  A++++QK   K L    +  L E   ++    L D      N  KV+E ++ + EI+ KE LIT+FD+    DL+LAIL +L+K MD     +L+    QL L + WNR DIA +KIF+       EN   F   +I   K EF+ LFL+NG +M +FLT   L  LY E    S      +   L      RN +   L D++ LL K+ G +              DE+   PF +LF W+VL+   + A + WE+T+ES+ LAL A+K+Y  +   +S  +  R   L  +KD FE LA+ ++EEC   D   A  +IEK+   +G + CLE+A  A  +KF+SC   QNS+   W  G      N+ +F   LC+ LPFL+    F+    +  S + D+        +      K+  +Y AP TKF  +++ + + +F +S+ +LF MK    +  E + I ++  M +E+  EMF  K + V ++++ WW F+ WN++D+  ++L+ + + LR P            I    +T Y L    FYLR  RL   +  LGPK+VMI KM+ +L+FY+ I+++ LL YG+  Q   +P RDF+ +   +I+ YPYW I+GEI L
Sbjct:   75 EQQRSLRQFILANFQRKECCLFEAKDGK------KCACGEVREKHD-GLLPAGPEEKWNEATHMRRSVTNAYGRITLKNEGFDNRDPIHFARVCDEDSMDKMLELMKTHWQLADPQKPSLCISVIGGAKNFKLEGRKKEVFHHGLIRAAQTTNAWIITSGLNLGITRVVGNALEEGRASHWEKSSRSSKLRCIGVAPWGYVLNRDHLINKRDPKIGELSLDVEYKISNVISKGQPVSLNANHTHYLLVDDGKRNRYGGSKSGVIKAKLQEQINQ----KEGISVVLLIVEGGLDIFEETQSMIQSNIPVVTCDNTGRAADIIAFAYKKVQKADKKTLSESQLADLRERMISTFSDNLKDPKTKKVNDKKVDENMSMLLEIVQKEKLITVFDMNRSDDLDLAILSALLKVMDA---KRLDDYKQQLQLSMTWNRPDIAAEKIFTEEHQWGTENLDKFALSAISQEKIEFLRLFLKNGLIMREFLTVGRLRSLYRESLAASSQASLQVRKLLAARTRCRNPWEPTLADIRVLLRKLVGKFHAPSMDKDVGTGGDDEQFERPFNQLFFWAVLLCKQDTAKFLWERTDESVPLALAASKVYNEMARALSSHEDGRKRMLQAYKDEFEELAVHVVEECQMVDPSKAELLIEKKVEAFGDFNCLELAASANCKKFVSCNSSQNSITSRWLNGLMHGTSNLRIF---LCVVLPFLL---PFEFLVRVEPSVRLDEGGRCAQLAH------KVRIYYTAPVTKFFANAIWYVIFIFLYSWFILFEMKAASISWLEWVIIAWICVMVVEEIREMFSSKADTVQEKLRDWWGFSAWNRLDLFTMLLALIGIFLRIPEATD-------AITTGVRTCYILAGVLFYLRVFRLYYANSYLGPKLVMIQKMVKELLFYMSILIVALLTYGVAAQALLYPTRDFTTSIFVDIVYYPYWQIYGEIYL 993

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Match: A0A183AFB2 (LSDAT_euk domain-containing protein OS=Echinostoma caproni OX=27848 PE=4 SV=1)

HSP 1 Score: 487.649 bits (1254), Expect = 3.338e-149
Identity = 333/971 (34.29%), Postives = 511/971 (52.63%), Query Frame = 3

Query:  438 PTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNI---EIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNK-KILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLS-QRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY---------EDCPRSFNLKRTI------------------FHFLGRNFSNG---------------LGDVKDLLTKIFGYYEDQCAMCDEEIIH----------------PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSP-LDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLI----------------------------------------------YRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPL-----KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGD-RIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQR-DFSLNTLPNIMDYPYWAIFGEITLN 2999
            PT +FG+I+F+ E   + +LTEFVR+S +D L+DVM+LM D+W++      +LCISV+GG KNF ++ + K +F      A +TTNA I+TSGLNLGI R VGDA+Q GQ   +D+ + +N L CLGI+PWG+V N+ +++  +  T + Y+VSN I    PVSLN+NHTHY+FVDE +R  Y  S+++ FR  L K+++  +      IPVVL+++EG +DVF +A   I+E +P+V+C GTGRASDL+  AF    K P K    D     PE   + L +KLI   +S   K + AL  I EI+    LIT FD+ +  DL+LAIL++LIK     ++S++NT   QL L   WNR DIA++KIF   V +  E+    + E+++  K EFV + LQNG +M  FLT   L +LY         E C     L++ +                  F F+    +                 L  V  L  K+ G + ++    D E +                 PFQELF+W+VL +  + A +FWE+ E+SL LAL+A  +Y  +++  P  DT      + + D FE LA++LLEEC+  D ET  +++E E   WGGY CL +A KA  +KFIS + CQNSL + W  G   + F   + +F P L+                                              +R S D        +   D +     TN    P      KL   Y AP+TKF ++++A+   + +FSY +LF +   Q T+ E + + Y I + ++   ++    T   G  +++ W   N+   +DI+ ++L+ ++M LR  L            +  +KT Y+L +   Y+R  RL   H  LGPK+VMI +M+ +L+ ++ I+ +ILL+YG+++Q   +P R +F  + + ++  YPYW ++GE+ L+
Sbjct:    6 PTRAFGQIDFLTETAMSQRLTEFVRISDKDKLEDVMELMKDHWHMMEPHKPSLCISVIGGAKNFALEGRRKDVFN----TAAQTTNAWIVTSGLNLGIVRVVGDALQEGQTWHFDRRRLSNQLRCLGISPWGYVLNRDELICSSYSTPVLYRVSNVIETGRPVSLNENHTHYIFVDEGKRLRYGGSESAKFRARLGKQMALPQQAGGWGIPVVLVVVEGGHDVFIDARDCIRERIPVVVCCGTGRASDLMNLAFYFRMKQPSK----DFTAFRPE-EESILLQKLIP--ISGKAKADSALEMIIEILRDPKLITTFDMNKSDDLDLAILFALIK-----TNSRINT---QLELAFTWNRSDIAEEKIFRQGVRVEPESLEPTMMEALLQDKPEFVRILLQNGIIMRQFLTVERLHELYNKSTHRDAFERCLAQKGLRKPLLPKVSDRKIAPHSQSEGKFDFVLSQVAATANVFPIKLPQAAPVYLSTVSRLSRKMIGRFTNKIYDQDTEELRRRPNDWDSFRNFTFSSPFQELFLWAVLHQRQQMALFFWERAEDSLTLALIACALYADMIKSLPQYDTETQAEYTRYMDEFEMLAVRLLEECYSMDPETTLFLVENEAPLWGGYNCLNLADKATRRKFISSVACQNSLFYAWSHGTQASPFVFTVTLFCPLLLLSDRFVEFDDKRNIGSGVRRVMDERRPSVLWRPTSPSRTSGQLSTYHRTSADAEIDFGLKRHLTDGAEDYSATNVTRQPRMTLKNKLEILYTAPRTKFFLNTIAYIAFLLFFSYTLLFKIISTQITVEEAVTMTYFITLFVDIIRQI--CVTPGTGSYKLRLWVKTNSLVYLDIIAMLLALVSMFLRIGL---------ASTFTVAKTFYALTLIVCYMRVFRLYGFHPALGPKLVMIQRMIAELILFLFIVAVILLSYGVSVQALLYPNRSEFDSSAIRDVFYYPYWNLYGELGLD 946

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: trpm3 (transient receptor potential cation channel, subfamily M, member 3 [Source:ZFIN;Acc:ZDB-GENE-060531-95])

HSP 1 Score: 273.478 bits (698), Expect = 3.438e-74
Identity = 269/957 (28.11%), Postives = 450/957 (47.02%), Query Frame = 3

Query:  504 FVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYK-VSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLL--GEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHF----------------LGRNFSNGLGDV---------------------KDLLTKIFGYYEDQCA-------------------MCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDY----FENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN----SYVIHE----------------SKKKDD-----TSNKGYFTNSGNW--------------PL--KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQLI 3008
            +VR+S++   D ++ LM   W +E+  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   K  +  Y+ +SN   L++   LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L  G  + E               ++ E  R+ L   +      +  +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  M+ FLT   L +L E          T++H                 L  ++   L D+                     + L   +FG   D                      + D EI H   PF EL +W+VL++  + A +FW+  EE++  ALVA K+ K  M     +   +E +S   ++    F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL + LP  I    F N    SY+  E                +K KD+     T+  G  ++  +               P+  K+ +FY AP  KF  H++A+   +  F+Y+VL  M  +  +  E + I Y+    IEK  E+   +  K+  ++K W     WN  D++ +++ ++ M+LR            +M Y   + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q    P  D S     NI   PYW I+GE    Q I
Sbjct:    3 YVRVSYDTKPDLLLHLMTKEWQLELPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDLV-GKDVVRPYQTMSNP--LSKLTVLNSLHSHFILADNGTTGKYGAE--VKLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGG------------LINESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSMHRFLT---LSRLEELYNTRHGPSNTLYHLVRDVKKSEETLYLQGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFSFPFHELMVWAVLLKRQKMALFFWQHGEEAMAKALVACKLCKA-MAHEASENDMVEDISQELNHNSREFGQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGLLLPPSILSLEFKNKDEMSYMPQEQEAYLQEKDSDEADKPAKDKDEEDMEFTAMLGNVSSEASRKKVVEEVQHRHRLIPVGRKIYEFYNAPIVKFWFHTMAYVGYLMLFNYIVLVKMD-LWPSPQEWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQ-EYWNITDLMAILIFSIGMVLRL-------QDPPLMSY--GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPNEDPSWMLARNIFFMPYWMIYGEAPCGQNI 909

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: hrc (transient receptor potential cation channel subfamily M member 4-like [Source:NCBI gene;Acc:103047479])

HSP 1 Score: 249.21 bits (635), Expect = 6.438e-67
Identity = 240/970 (24.74%), Postives = 432/970 (44.54%), Query Frame = 3

Query:  264 IKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK----DKIPYNKVNDW--SIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSL---CCLGIAPWGFVKNKKILEHAKGTI-IKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNK-----EPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEM---YRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKED--HDLELAILYSLIK--RMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLG------------------DVKDLLTKIFG-----YYEDQCAMC----------------------DEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINL--FQCILCIFLPFLIYR--------------------RSFDNSYVIHES-------KKKDDTSNKGYFTNSGNWPLK------------LVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIH---EILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRC---SKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISK 2831
            IKK+     C  FVE S   SN    C CG  +  H      D      V+ W  ++HS     PT++FG++EF G    + + + F+RLS +        ++   W +    L +SV+GG    K+K K + +  QGL++A ++T A IL+ GL  GI R +G+A+++     +  A  ++SL     +G+APWG V  +  L + +G+    Y V+N     +   L+ NH  +L VD+           + FR  LE  +SQ+   K       IPV+  L+ GE  +       +K+ +P ++  G+G  +DL+ +    +   P+                  R  + +K++    S PD V++ ++ +  +   + LI+++ ++++   D +  +L +L++  +   +SD+ L+T   +L L + WNRVDIA+ ++F+G +    E+   F+ ++++N K +FV LF++NG  + +++T   LE+LY    RS +     +  L R+ S   G                  +V  LL  + G     +Y+D+  +                        +  + P+  LF W+VL    E A +FWE T ES+  AL A K+ + L ++   +T    +L      FENLA  +  +C+ + +  +  +++K+++ W G TCL++A +A+ + F S    Q  L   W    + N   ++ +L +F+P L Y                     ++ D  ++  E+       K+      +  FT  GN P K              QF+ AP T F  + L + + +  F+YV+L   K          E+L   ++  +  E+    F      V  RI+  +  + W+K D++ + L  + +  R             M  R    ++    L    F LR + + ++HK LGPKI+++ K
Sbjct:   31 IKKRV----CTTFVEDS--FSNGHL-CQCGGSRDSHATVSLNDYFSSAIVSHWDSALHS--SEAPTDAFGEVEFGG---VSKRHSNFLRLSSDTPPATAYTILTSNWGLPKPNLVLSVVGGVGRSKVKPKLREVLRQGLVRAAQSTGAWILSGGLREGIDRCLGEAVRD-----HTTAASSDSLTKVVAIGVAPWGLVNLRDELVNPEGSYPAGYFVTNTS--RDSYCLDTNHQAFLLVDDGS--TGRRGGEARFRAGLENYISQQRTGKLGSGSMDIPVLCTLVSGELYMLERLDLSLKKCIPWMVLAGSGGLADLVTDVLENVAAAPVLPAGGAEGEGEATTKINLRERVAEKVVKHFPSEPD-VDKLVDKLLNVHKSQDLISIYHLEQEGPEDFDTVLLKALVRASKQRLSSDASLST--EELKLAVTWNRVDIARSELFTGDIQWKNESLESFMTDALVNDKPQFVRLFIENGLNVQEYMTFGRLEELY----RSISDSSVAYTLLQRHLSERQGVAGTGWPAADPAKGLTLYEVAQLLEDLLGDVCQPFYDDKLKIQGITSRRKTIKKLTTVLQEGEYRQQRCVFPWASLFTWAVLQNRSEMAVFFWEMTPESVLSALSACKLLRELCKLEN-ETETKHSLKELAMKFENLAHDVFSKCYQSSESRSFVLLKKKSVVWRGATCLQMAMEADARHFFSHDGVQTLLSQIWWGDMDRNTENWKLVLTLFIPPLCYTSLISFREVEEAEDGTPEEAPKARDIDWLYAETVFSFADIKRIQTKQEELRFTPKGN-PTKKSPQKQCFLLSRWKQFWYAPVTAFLGNMLMYFLFLLLFAYVLLVDFKPPPPKGPSPMELLLYFWVFTIVCEEIRGTFFIGNMTVRQRIRQ-YTQDLWHKCDLIAITLFLIGLCCR-------------MFRRSFWFARAALCLDYMVFTLRLIHIFAIHKQLGPKIIIVGK 956

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: trpm4a (transient receptor potential cation channel subfamily M member 4 [Source:NCBI gene;Acc:103041664])

HSP 1 Score: 223.016 bits (567), Expect = 1.236e-58
Identity = 196/772 (25.39%), Postives = 338/772 (43.78%), Query Frame = 3

Query:  195 TDGSKNSNVNFNANDEKNH--LKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK----DKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTI-IKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLS-QRTK-----NKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLK------KKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDH--DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE------------------------------DCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFG------YY---------------------EDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFN--INLFQCILCIFLPFLIY 2270
            ++  + S  N +   EK+   +   IKKK     C  F+E S+   +   +C CG  ++ H      D      V+ W         PT++FG++EF G      + + F+RLS +     V  +M  +W +    L +SV+GG    K+K   + +  QGL+ A ++T A I+T GL  G+   VG+A+++        +   + +  +G+APWG V N++ L +A+G+   +Y + N     +   L+ N+  +L VD+           ++F   +E  +S QRT      N E IPV+ +LI GE  V       +K+  P ++  G+G A+D++ E         +  L P   P   ++  +S        K++I K+      + + ++    I     LIT+F   +D   D +  +L +L++     S S  +  + +L L + WNRVDIAK ++F+G +    E     + ++++N K +FV +F++NG  + ++LT   LE LY+                              D P   + K        R  S  L +V  LL ++FG      YY                     +   A       HP+  LFIW+VL    E A YFWE   ES+  AL A K+ + L ++     +++ ++      FE LA      C+ + +  +  ++ + +  WGG TCL++A  A+ + F S    Q  L   W    N    +++ +    +P LIY
Sbjct:    4 SEKEEESARNGSGKGEKDQSWVPKIIKKKV----CTTFLEDSQ---SNGDRCQCGSERAAHSSSATGDFFGSAVVSQWDTAVHTSEYPTDAFGEVEFAG---AGRRHSHFLRLSCDTPASLVYSIMTVHWGLPPPNLVVSVMGGGGREKVKSWVRDVLRQGLVLAAQSTGAWIMTGGLKEGVGHCVGEAVRDHVAAA--SSPSQSKVVAIGVAPWGLVANRQQLVNAQGSFPARYYIQNTS--HDSCYLDNNYQAFLLVDDGSVGHRGGE--TNFITNMEDYISNQRTGIWGSGNIE-IPVLCMLISGEASVLKRMDMSLKKATPWLVLDGSGPAADMISEL--------LDDLSPAASPADGDVRDSSTAELRNRTKEIIKKHFPAEKVLEKLVDRALSIYQNRALITVFHGDQDSPDDFDTVLLKALVRACRQMS-SDASEYTEELKLAVAWNRVDIAKSELFNGDIQWQYEALKDCMTDALVNNKPQFVRVFIENGLNILEYLTYQRLESLYQSLSDSSLAYSLLQKWLRERHSLVAMSPHSPDSPEKKSKKSLKVPPNVRELS--LYEVSRLLGELFGGMCQPFYYSVLDLDPGASNRKAAKQLNKLQADGAYGKRSCNHPWASLFIWAVLQNRSEMAIYFWEMAGESVLSALCACKMLRELCKLENETETKL-SIKELAQKFETLAHDTFSACYQSSESRSFTLLIRTSPVWGGVTCLQMAMAADARLFFSHDGVQTLLSQIWWGDMNSRTEVWKLVASFLMPPLIY 746

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: trpm4a (transient receptor potential cation channel subfamily M member 4 [Source:NCBI gene;Acc:103041664])

HSP 1 Score: 222.631 bits (566), Expect = 1.575e-58
Identity = 196/772 (25.39%), Postives = 338/772 (43.78%), Query Frame = 3

Query:  195 TDGSKNSNVNFNANDEKNH--LKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKK----DKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTI-IKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLS-QRTK-----NKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLK------KKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDH--DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE------------------------------DCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFG------YY---------------------EDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFN--INLFQCILCIFLPFLIY 2270
            ++  + S  N +   EK+   +   IKKK     C  F+E S+   +   +C CG  ++ H      D      V+ W         PT++FG++EF G      + + F+RLS +     V  +M  +W +    L +SV+GG    K+K   + +  QGL+ A ++T A I+T GL  G+   VG+A+++        +   + +  +G+APWG V N++ L +A+G+   +Y + N     +   L+ N+  +L VD+           ++F   +E  +S QRT      N E IPV+ +LI GE  V       +K+  P ++  G+G A+D++ E         +  L P   P   ++  +S        K++I K+      + + ++    I     LIT+F   +D   D +  +L +L++     S S  +  + +L L + WNRVDIAK ++F+G +    E     + ++++N K +FV +F++NG  + ++LT   LE LY+                              D P   + K        R  S  L +V  LL ++FG      YY                     +   A       HP+  LFIW+VL    E A YFWE   ES+  AL A K+ + L ++     +++ ++      FE LA      C+ + +  +  ++ + +  WGG TCL++A  A+ + F S    Q  L   W    N    +++ +    +P LIY
Sbjct:    4 SEKEEESARNGSGKGEKDQSWVPKIIKKKV----CTTFLEDSQ---SNGDRCQCGSERAAHSSSATGDFFGSAVVSQWDTAVHTSEYPTDAFGEVEFAG---AGRRHSHFLRLSCDTPASLVYSIMTVHWGLPPPNLVVSVMGGGGREKVKSWVRDVLRQGLVLAAQSTGAWIMTGGLKEGVGHCVGEAVRDHVAAA--SSPSQSKVVAIGVAPWGLVANRQQLVNAQGSFPARYYIQNTS--HDSCYLDNNYQAFLLVDDGSVGHRGGE--TNFITNMEDYISNQRTGIWGSGNIE-IPVLCMLISGEASVLKRMDMSLKKATPWLVLDGSGPAADMISEL--------LDDLSPAASPADGDVRDSSTAELRNRTKEIIKKHFPAEKVLEKLVDRALSIYQNRALITVFHGDQDSPDDFDTVLLKALVRACRQMS-SDASEYTEELKLAVAWNRVDIAKSELFNGDIQWQYEALKDCMTDALVNNKPQFVRVFIENGLNILEYLTYQRLESLYQSLSDSSLAYSLLQKWLRERHSLVAMSPHSPDSPEKKSKKSLKVPPNVRELS--LYEVSRLLGELFGGMCQPFYYSVLDLDPGASNRKAAKQLNKLQADGAYGKRSCNHPWASLFIWAVLQNRSEMAIYFWEMAGESVLSALCACKMLRELCKLENETETKL-SIKELAQKFETLAHDTFSACYQSSESRSFTLLIRTSPVWGGVTCLQMAMAADARLFFSHDGVQTLLSQIWWGDMNSRTEVWKLVASFLMPPLIY 746

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:111197571])

HSP 1 Score: 213.001 bits (541), Expect = 3.077e-55
Identity = 160/521 (30.71%), Postives = 268/521 (51.44%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSK---------ELSNKQTKCLCGELKSEH----------------KKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVS----LNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLS-QRTKNK--EPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY--EDCPRSFNL 1703
            K +I+  F   +C + +  SK         ++  +  +C CG L  +H                 + + P+    +WS+ +  E  PT+++G I F G   +++   ++VRLSH+   + +++LM   W +E+  + ISV GG +NF +  + K +  +GLIKA  TT A ILT G+N G+ + VGDA++         ++    +C +GIAPWG ++N+  L   +  +  Y+      L  P+S    LN  H+H++ VD      Y      + R  LEK ++ QR   +  + +PVV L+ EG  +V     + ++E+  VP+V+C GTGRA+D+L    ++ +        PDGV    E    +  KK    N+S  D V+     +E + +KE LIT+F V  EDH D+++AIL +L+K  D ++         QL L L W+RVDIAKD +F     L  ++    + ++++  + +FV+L ++NG  M+ FLT + LE+LY  +  P + NL
Sbjct:    4 KSWIESTFTKRECVYILPVSKDPHRCLPGCQICQQLVRCCCGRLVRQHVGFTASLAMKYSDMKLGEAQPPHE---EWSVENHTEQSPTDAYGIINFQGG--SHSYRAKYVRLSHDSRPEAILRLMLKEWQMELPKIVISVHGGIQNFDLHPRIKQVVGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKE------HSSRSARKICTIGIAPWGVIENRNDLI-GRDVVAPYQT-----LLNPLSKLNVLNNLHSHFILVDNGTVGKY--GAEVNLRRDLEKHINLQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADILSFVHKQTED---DGGLPDGV----ETDIIATVKKTF--NLSQNDAVHLFQTLMECMKNKE-LITVFHVGSEDHQDIDVAILKALLKGTDASA-------FDQLVLTLAWDRVDIAKDHVFVYGQKLLVDSLEQAMLDALVMDRVDFVKLLIENGVSMHRFLTISRLEELYNTKQSPTNPNL 488

HSP 2 Score: 119.783 bits (299), Expect = 1.370e-33
Identity = 110/430 (25.58%), Postives = 208/430 (48.37%), Query Frame = 3

Query: 1830 HPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCL---MEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLI----YRRSFDNSYV-----IHESKKKDDTSN--------------------------KGYFTNSGNWPL--KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            +PF EL +W+VLM+  + + +FW+  EES+  ALVA K+ + +    + S +     E L  + + F  LA+ LLE+    D+  +  ++  E   W   TCL++A  +  + F++    Q  L   W    N+   + ++ IL I +P  I    Y+   + +++      H+   +D   N                              T S   P+  K   FY AP  KF  ++L + V +  +SYVVL  +     +  E   I+Y+    IEK  EMF  +  K+  +IK W++ + +N+ D + +++ A+   LRF       +G++ +  R    IY L + ++Y+R L +++V++  GP ++MI KM+  + + ++IM ++L+ YG+  +   +P  +   + + +++  PYW ++GE+
Sbjct:  617 YPFNELLVWAVLMKRQKMSLFFWQHGEESMAKALVACKLCRSMCYEAKKSDVVDDTSEELKEYSNEFGTLAVDLLEQSFRQDELMSMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMERLNMRKNSWYKVILSILVPPAILALEYKSKAEMAHIPQSQDAHQMTMEDSEHNLQNPDDIQMDVFKETRINDHVEVKHETEVVTRSRRLPIMRKFHAFYHAPIVKFWTNTLFYLVFLMLYSYVVLVKLPIFP-SPQEWAVILYIFTSAIEKIREMFMSEGGKISQKIKVWFS-DYFNRSDFIAIVMFAVGFGLRF------GSGNVFIAGRL---IYCLNIIFWYVRLLDILAVNQQAGPYVMMIGKMVANMFYIVVIMCVVLVTYGVPRKAILYPNSEAEWSLIIDVVFQPYWMMYGEV 1035

HSP 3 Score: 45.0542 bits (105), Expect = 1.370e-33
Identity = 43/131 (32.82%), Postives = 69/131 (52.67%), Query Frame = 2

Query: 2978 IWGD-YIESIDLPWCDDKTTNYNISNECPELNYFVPVXXXXXXXXXXXXXXXXXXXVFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSIFAHAFDFFYSLC---------GNQCEKTEENEKNL 3340
            ++G+ Y   ID+  C + T N N+ + C    +  P L A+Y+FI  IL++N+L A FN ++ ++   S  +WK+  +  +M Y+ KP+ P P  IF H   F   LC         G +   TEE++K L
Sbjct: 1031 MYGEVYAYEIDV--CANSTEN-NMDHLCTTGVWLTPALQAVYLFIQYILMVNLLIAFFNNVYLQVMSISNLVWKYQRYHFIMAYHDKPVLPPPLIIFYHISSFLSFLCKRRKKDSAYGPKLFLTEEDQKKL 1158

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Sea Lamprey
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2])

HSP 1 Score: 293.123 bits (749), Expect = 6.204e-83
Identity = 277/962 (28.79%), Postives = 454/962 (47.19%), Query Frame = 3

Query:  501 EFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEP----VSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQ---RTKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIF----SGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLY--EDCPRSFNLKRTIFHF--LGRNFSNGLGDVKDLLTKIFG------------------YYEDQCAMCDEE--------------------------IIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCL---MEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLP----FLIYRRSFDNSYV-----IHESKKKD--------------------------------------------DTSNKGYFTNSGNW--------PLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFP--LLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            ++ R+S++   D +++LM   W +E+  L ISV GG +NF++  K K +F +GLIKA  TT A I T G+N G+   VG+A++         ++ ++ +C +GIAPWG ++N+  L      +    VS    L+ P      LN  H+H++ VD+     Y     +  R  LEK ++    R    + +PVV L+ EG  +V     + + E   VP+V+C GTGRA+D+L  AF         +L  DG   L +    ++KK     N S+   ++  L  + E + ++ LIT+F    EDH D++LAIL +L+K  +F+S       + QL+L L W+RVDIAK+ +F      +V L    W   + ++++  + +FV+L ++NG  M+ FLT T LE+LY   D  +  NL+  +  F  L  ++   L DV  ++  + G                   Y    A  D                              +PF EL  W+VLM+    A +FW+  EESL  ALVA K+Y+ L    + S  D  + + L   +  F  LA+ LL++    D+  A  ++  E   W  +TCL++A  +  + F++    Q  L   W    N+   + F+ IL I +P     L Y+   + S++     +H+  +++                                            D    G+    G W          ++ +FY AP  KF  ++LA+   +  F+YVVL  ++++  ++ E   I+YL    IE+  E+F  +  K G +IK W +   WN  D L ++L  +A+ LR    LL++            +K +YSL V ++Y+R L + +V++N+GP I+MI KM++Q    +IIM I+LL++G+  Q   F + D S     NI+  PYW IFGE+
Sbjct:    1 QYARVSYDSRPDLLLQLMVKEWQMELPRLLISVHGGLQNFELHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKE------HASRSSHKICTIGIAPWGVIENRGDLVGQDSHV----VSPYQTLSNPLSKLNLLNSLHSHFILVDDGTVGKYGAE--AQLRRELEKHIATVACRAGMGQGVPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAADIL--AFLHKNTDDTGEL-CDG---LHDEIVGTIKKTF---NFSHGQAMH-LLQTLLECMRRKELITVFHTGSEDHSDVDLAILTALLKGTNFSS-------ADQLNLALAWDRVDIAKNHVFVYGQHWMVRLEWARWRRPMLDALVMDRVDFVKLLIENGVSMHKFLTITRLEELYNTSDHHQMSNLRILLHRFSHLPPDYKITLIDVGLVIEFLMGGAFRSMYTRKRFRLLYHNLYGQHRASVDNTRQRKQKMSTASGVGVTLDGSDPECSCFAYPFNELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLAGEAKQSREDELKWKRLWCARVKFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFKVILSILMPPSILMLEYKSKAEMSHIPQSEELHQMGQEEREHRAAATRDIPMQRCLSRRVFLRLLSFAIRILLLRTVGNGSAADGGESGHKEEEGIWIRPSGLSLSRRIYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKLQQLP-SVQEWFVILYLFMSAIERVREIFMSEPGKFGQKIKVWLD-GYWNINDSLGILLFFVAVALRSQSHLLIE------------AKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMWQQCMLMIIMAIVLLSFGVARQAILFKEADPSWYLARNIVFQPYWMIFGEV 919

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Sea Lamprey
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2])

HSP 1 Score: 271.166 bits (692), Expect = 1.212e-75
Identity = 255/935 (27.27%), Postives = 426/935 (45.56%), Query Frame = 3

Query:  504 FVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKN----HTHYLFVDEHERFDYSNSKASDFREALEKK--------LSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPM--LPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIF---SGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYE-------DCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEE--------------------------IIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCL---MEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLP----FLIYRRSFDNSYV-----IHE--SKKKDDTSNKGYFTNSGNW--------PLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMF--QYKTNKVGD-----------RIKYWWNFNNWNKVDILMVILSAMAMILRFP--LLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL--ICLGVMT 3026
            + R+S++   D +++LM   W +E+  L ISV GG +NF++  K K +F +GLIKA  TT A I T G+N G+   VG+A++         ++ ++ +C +GIAPWG ++N+  L      +    VS    L+ P+S        H+H++ VD+     Y     +  R  LEK         L+ R    + +PVV L+ EG  +V     + + E   VP+V+C GTGRA+D+L    +             G  M  L  +     +K+L+          +   +    I     + TL                 + R    + +  ++ + QL+L L W+RVDIAK+ +F      ++L    W   + ++++  + +FV+L ++NG  M+ FLT T LE+LY        + P+   L  +    +G N +     + +LL  I G         D                              +PF EL  W+VLM+    A +FW+  EESL  ALVA K+Y+ L    + S       E L  +   F  LA+ LL++    D+  A  ++  E   W  +TCL++A  +  + F++    Q  L   W    N+   + F+ IL I +P     L Y+   + S++     +H+  +    D    G+    G W          ++ +FY AP  KF  ++LA+   +  F+YVVL  ++++  ++ E   I+YL    IE+  E+     +T K              +IK W +   WN  D L ++L  +A+ LR    LL++            +K +YSL V ++Y+R L + +V++N+GP I+MI KM+  +   +IIM I+LL++G+  Q   F + D S     NI+  PYW IFGE+   ++  IC+ V+ 
Sbjct:    1 YARVSYDSRPDLLLQLMVKEWQMELPRLLISVHGGLQNFELHPKLKQVFSKGLIKAALTTGAWIFTGGVNTGVVNHVGNALKE------HASRSSHKICTIGIAPWGVIENRGDLVGQDSHV----VSPYQTLSNPLSKLNLLNSLHSHFILVDDGTVGKYGAE--AQLRRELEKHIALQKIHTLACRAGMGQGVPVVGLVAEGGPNVIVTVLEYLLEEPPVPVVVCEGTGRAADILAFLHKNTDDTGWAHTHRHGQAMHLLQTLLECMRRKELVGTRARVRTHTHTCTHGSAAISGGPSVETLIA---------------LHRTGAAAGTNFSS-ADQLNLALAWDRVDIAKNHVFVYGQHWMALMWARWRRPMLDALVMDRVDFVKLLIENGVSMHKFLTITRLEELYNTVSGPLTNPPKRPLLANSRSPPVGLNCTLNPPVIGNLLLMILGGTCSAIQAVDNTRQRKQKMSTASGVGVTLDGSDPECSCFAYPFNELLAWAVLMKRQRMAMFFWQHGEESLAKALVACKLYRSLAGEAKQSEAVEDSSEELKQYSTEFGQLALDLLDQSFRQDERMAMKLLTYELRNWSNFTCLKLAVSSRHRPFVAHTCTQMLLADMWMGRLNMRKNSWFKVILSILMPPSILMLEYKSKAEMSHIPQSEELHQMGNGSAADGGESGHKEEEGIWIRPSGLSLSRRIYEFYHAPIVKFWFNTLAYIGFLMLFTYVVLVKLQQLP-SVQEWFVILYLFMSAIERVREVSDGARETRKAAGLRSDSEASAHRKIKVWLD-GYWNINDSLGILLFFVAVALRSQSHLLIE------------AKIVYSLDVIFWYVRLLDVFAVNQNVGPYIMMIGKMMANMFSIVIIMAIVLLSFGVARQAILFKEADPSWYLARNIVFQPYWMIFGEVYAPEIDGICVAVLA 893

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BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Sea Lamprey
Match: trpm2 (transient receptor potential cation channel, subfamily M, member 2 [Source:NCBI gene;Acc:799412])

HSP 1 Score: 127.487 bits (319), Expect = 8.554e-30
Identity = 124/521 (23.80%), Postives = 217/521 (41.65%), Query Frame = 3

Query:  252 LKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKI--PYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTN---ALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGN--NSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTG---RASDLLGEAFREMQKYPIKQLRPDGVPMLPEM---YRNSLKKKLIDKNVSN--PDKVNEALNYIEEIIHKEYLITLFDVKEDHDLEL-------AILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNG 1748
            +K +I +      C +++E S      +  C C   +SEH    +  P      W         PT +FG I+F G      +L +FVR+ ++     + KLM ++W++++  L ISV GG KNF +K + + IF  GL K  ++T    A I+T G   G+ ++VG+++++     +  A G+    +  +GIA WG +                              NK H     +D   +F           EA + +LS    N     +V     G+Y V      R+++ +      G+G   R+S  +G             +R +    L +M    R+  K  LI     +    ++N ++ + ++ I+ + LI LF +       L       A++   I      ++    +   QL L L WNRVDIA  +IF+        +    +  +++  + EF+ LF+++G ++ ++LT   LE LY   P S     ++ H L R  S G
Sbjct:    4 VKAWISQNIKMKVCCWYIESSTAGGAARRVCECRHPRSEHANTALLKPTLLGQKWEPAKHTANEPTNAFGDIQFTG---LGQRLGKFVRVGNDTEPSVLFKLMMEHWHLDVPNLLISVTGGAKNFHLKPQLRTIFRHGLNKTARSTGIQGAWIITGGSYAGVMKYVGESVRD-----FALASGSKEGKIVAIGIATWGIIH-----------------------------NKEH----LIDAQGKF----PAEYPMDEAGQGRLSCLDNNHSHFILVDNGTHGQYGVEIVLRARLEQYIS-TQHTGSGGECRSSKAVG-------------VRGNCAARLWDMCVRVRHCGKIVLIIMQAXSMVVREINSSVIFEKQNIYFDVLICLFFLGRIISRALLTGTYACAMVVVCISASRGEANKAQESCDHQLRLALAWNRVDIATSEIFTDDRKWQTGDLEQVMDAALLENRPEFISLFVEHGLILREYLTWARLESLYNGAPAS-----SLLHILLRRISEG 460

HSP 2 Score: 126.716 bits (317), Expect = 1.255e-29
Identity = 92/339 (27.14%), Postives = 178/339 (52.51%), Query Frame = 3

Query: 1833 PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINL--FQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIY--LICMNIEKFAEMFQ--YKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISK 2831
            P ++LFIW+VL+   E AN+FW + ++ +  AL+A+K+ K +++    D+ R   +    D +E LAI LL+EC+  D+  A  ++ ++  +WGG TCL +AY A ++ F S    Q  L   W  G +++L  ++ ILCI  P LIY R     +V++                    P +   F+ AP T F  + +++ + ++ F+YV+   +   Q+T     +++Y  ++ + +E+  ++F    K  +    ++Y  +   WN++DIL ++L  + +I R   L+ N   +    ++  +++  +    F LR + + +V+K LGPKI+++ +
Sbjct:  549 PERDLFIWAVLLNRRELANFFWSQGKDCMAAALMASKLLKAMVQEED-DSDRTSDMLAQADNYEQLAIGLLDECYKDDELRAQKLLIRQLHSWGGATCLSMAYHANNKSFFSHSGVQALLTQIWWGGMSVDLKTWRVILCIIFPLLIYTRIITFRWVLYAHTCT---------------PTRWRNFWTAPITVFWANVVSYFIFLWLFAYVI---IMDFQYTPDWPEYVLYAWVLSLILEELRQVFTDPEKAGQWKAAVRYIKDI--WNRIDILALLLFTIGVICR---LIPNSINE--STFQAGRSVLCVDYMVFCLRLMHIFTVNKTLGPKIIIVKR 861

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Nematostella
Match: EDO30135 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1N0])

HSP 1 Score: 299.286 bits (765), Expect = 6.818e-83
Identity = 207/743 (27.86%), Postives = 366/743 (49.26%), Query Frame = 3

Query:  192 LTDGSKNSNVN---FNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFV-KNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKA--SDFREALEK-KLSQRTKNKE-PIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLF--DVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLK------------RTI-FHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEII---------------------HPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDY---FENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRA--GFNINLFQCILCIFLPFLIY 2270
            L DG  +S+V+   F +N      K +I + F   +C  FV KS ++S    +C CG  +  H +  +   + ++ W++ SC    PT ++G+I+F  E     K   ++R+SH+ + + V+ LM   WN+EI  L ISV GG K+F +K + + +F +GLIKA KTT A I+T G N G+ + VG+A++  Q       + N     +GIA WG V K   ++    G              +   L+ NH+H+  VD+     Y       S   EA+ K K   R++     +PVVLL++EG  +      + IK+ VP V+  G+GRA+ ++G A+    K   + +    + ++   Y + ++ K+++  V      ++  + I++++  E +I+++  D +   D++LAIL +L+K       +  ++  +QL+L L WNR+D+AK  IF+     + E  +  +  ++++ K EF ELFLQNG  M +FL+   L KLY + P +  +K            +TI    +G      +GD+ +   +  G+Y  + A   E ++                      P+ ++F+W+VL    E A   WE   E +  AL+A+++ K +   +  D +  +  S+  D+   FE  A+ +L+EC + ++  +  ++ +E   +   T LE+A  AE Q FI+   CQ  L   W      N   ++ ++C++LP LI+
Sbjct:    9 LYDGGDSSHVHLNKFGSNQLSQSKKSWIARNFSRRECIRFVPKSHDVS----RCKCGRPRERHSQQALESGQGSEEWNVASCTTKHPTNAYGEIDF--EGYGGQKRAPYLRMSHDTDANLVITLMLKRWNLEIPNLVISVTGGAKSFVLKPRLREMFRRGLIKAAKTTGAWIITGGTNTGVMKHVGEAVKEQQLMFGSDTQVN----VIGIATWGIVDKQSDLISEKNGKYPALYSMEPTPGHQGAMLDPNHSHFFLVDDGTEGKYGVEIGMRSRIEEAIMKVKTDSRSEAGSIGVPVVLLVLEGGPNTVATMYELIKKKVPAVVIDGSGRAASVVGFAYNHTIK---RNVDGQTINVIDPQYEDEVRAKVVE--VFGAKGADKTYSMIKDVLEDEKMISVYSLDGEISQDIDLAILKALLK-------ANRSSPVAQLNLALAWNRIDLAKSDIFTEEQQWTTETLSAAMLTALLDDKAEFAELFLQNGLSMREFLSLDILCKLYAEVPGNTTIKPLLQKEMGKRQVKTIDMDVVGEVIEELMGDMFESYYRKDGHYFGELASYAEGLVLKNRKSSKDLLANINRIDPLPTPYLDVFLWAVLCNRRELARVLWEAGREPMAAALMASRLLKRMASRAQEDNTITDISSDLYDHARLFEERAVGVLDECFNENETLSQTLLVRELDHYSRMTALELAVSAESQDFIAHTSCQVLLTRLWMGTMAMNTRWWKVLVCLYLPVLIF 729

HSP 2 Score: 73.559 bits (179), Expect = 4.850e-13
Identity = 54/174 (31.03%), Postives = 100/174 (57.47%), Query Frame = 3

Query: 2499 EILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQ-----RDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            EI+   ++  + IE+  ++       + D++  +++ + WN VDI  + +  +A+ILRF     N       I+  S+ I SL + +F +R L++ SV++ LGPK+VMI KM+  L  +III+ +  +AYGI +    FP      R+ +  T+ +++ YPYW ++GE+ L+++
Sbjct:  879 EIVLYFWVFTILIEEIRQLAAKPPKYIKDKVSVYFS-DTWNFVDIFSLTVFIIAIILRF---FTN-----SRIFTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQDLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNTWVTITSVVQYPYWQMYGELFLDEI 1043

HSP 3 Score: 52.373 bits (124), Expect = 1.404e-6
Identity = 18/47 (38.30%), Postives = 30/47 (63.83%), Query Frame = 2

Query: 3143 VFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSIFAHAFDF 3283
            +FNY F+R+  +S ++WKF  + LV EY+++P+F  P  +  H   F
Sbjct: 1084 IFNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPPLVLLGHILIF 1130

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Nematostella
Match: EDO47658 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLT7])

HSP 1 Score: 194.897 bits (494), Expect = 2.243e-50
Identity = 147/476 (30.88%), Postives = 249/476 (52.31%), Query Frame = 3

Query:  432 TVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNS--LCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALE-----KKLSQRTKNKEPIPVVLLLIEGEYDVF---FEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKN---VSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLEL--AILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRS---FNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQC 1805
            T+PT++FG++EF G         +++RL+H+ + + V++L+   W +++  L ISV GG KNF +  K K +  +GL+KA +TT A ++T G N G+ R VG+A++        +   N +  +  +GIA WG V +K++L + K  ++ Y++++  + +    L+ NH+H++ VD     +Y    +  FR +LE     KK++Q+      +PVVLL++EG  +      E+  R    VP+VI  G+GRA+D+L  A R +           GV  + E +R  L K  I+K+    S  D+++   N ++ +  +E+ +T+F V +D  LE+  AIL +L+K       S+ + L  QLSL L W+R DIAK +IF+             + E++++ + EFV+L L NG  M +FLT   LE+LY     S       R   H+    ++N    +        G Y  +C
Sbjct:   14 TLPTDAFGELEFQG--AGQPSRAKYIRLAHDTDPELVLRLLCGEWALDLPKLLISVTGGAKNFILSPKIKRVLREGLLKAAQTTGAWVITGGTNTGVMRHVGEAVKGHTVMSRGEQLKNTAHQVHLIGIASWGIVDHKEMLVNPKVEVVPYQMTSS-MQSRGACLDNNHSHFILVDNGTDGEYGGEIS--FRASLENLIASKKMAQKFHG---VPVVLLVLEGGPNTIRTVLESVSRCPA-VPVVIAEGSGRAADILAFAHRFIAP---SNGEMSGVADVVE-HRQLLHK--IEKSFAECSPEDRLSIYQNVLKCVAKREF-VTIFCV-DDGGLEVDKAILRALLK-------SQHSQLEDQLSLALVWDRADIAKTEIFTEDQKWEVPMLETAMMEALLHDRVEFVDLLLDNGVSMANFLTVKRLEELYRKVRGSKANHASSRIFMHYHNDTYTNASTQMNK---HTHGIYTQRC 462

HSP 2 Score: 83.5741 bits (205), Expect = 3.927e-16
Identity = 100/382 (26.18%), Postives = 171/382 (44.76%), Query Frame = 3

Query: 2019 FENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTW----RAGFNINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTS---------------------NKGYFTN----------SGN--WPL----------KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNF----------NNWNKVDILMVILSAMAMILRF-PLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            F ++A+ LL+EC+ A+   A  ++    + WGG T L +A  +  ++F++   CQ  L   W    + G+N +L + +L I  P LI+   F +   +      DD S                     N GY  +          SGN   P+          +++ FY AP TKF  + + + + +  FS+V+L  +  +  +I E + I ++  +  E+  ++          R+   WNF          N WN  D   ++L  +A+ LR  P  L           R    +YSL +  + +R L + SV K+LGP +VMI +M   +M++++IM++ LLAYG+  Q   FP    S   +  I   PY+ ++GE+
Sbjct:  595 FYDIALGLLDECYKANDVLAQRLLIYHPVYWGGRTSLSLAVASRHEEFVAHSCCQKKLTEIWMGALKTGYNGSL-KVLLGILFPPLIFALEFRSREEMQRVPTTDDDSADDLPPDFDPYHHREPGSAQYNDGYLGDGVAFVKNRKSSGNEEEPIVEIRLLGLGKRIIGFYNAPITKFWSNLIVYLLFLVVFSHVILIELPPVP-SIEEWVLIGFVFSLCAEEVRQV----------RVINVWNFSFFESSDWASNVWNLCDGFAMVLFFLAVGLRLNPGTL-----------RIGHLVYSLDIMLWIIRLLDIFSVSKDLGPYVVMIGRMTIDMMYFLVIMVVFLLAYGVAQQAILFPHEKPSWELITKIFFRPYFQVYGEL 953

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm3 (transient receptor potential cation channel subfamily M member 3 [Source:NCBI gene;Acc:100533512])

HSP 1 Score: 306.99 bits (785), Expect = 7.012e-85
Identity = 296/1044 (28.35%), Postives = 490/1044 (46.93%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH----------KKDKIPYNKVND-----WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYK-VSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHF--------LGRNFSNGLGDV---------------------KDLLTKIFGYYEDQCA-------------------MCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNI---NLFQCILCIFLPFLIYRRSFDN----SYVIHE-------------------------------SKKKDDTSNKGYFTNSGNW----PL--KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL 3005
            K +I++ F   +C   +  +K+      +C CG L  +H          + DK      ND     WSI    +  PT++FG IEF G   +N  +  +VR+S++   D ++ LM   W +++  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   K  +  Y+ +SN   L++   LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L    +  ++  I          + E  R+ L   +      +  +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  ++ FLT + LE+LY       N   T++H         L  ++   L D+                     + L   +FG   D                      + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N ++ F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W     +   +  + IL + LP  I    F N    SY+  +                                K   DTS K       +     PL  K+ +FY AP  KF  H+LA+   +  F+Y+VL  M  +  +  E + I Y+    IEK  E+   +  K+  ++K W     WN  D++ +++ ++ M+LR             M Y   + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q    P  D S     NI   PYW I+GE+  +Q+
Sbjct:   44 KSWIERAFSKRECVHIIVSAKD----PHRCCCGRLIGQHVGLPPGISSSQNDKAERMAKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSYDTKPDLLLHLMTKEWQLDLPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDLV-GKDVVRPYQTMSNP--LSKLTVLNSLHSHFILADNGTTGKYGAE--VRLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGI----------INESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSVHRFLTLSRLEELYNTRHGPSN---TLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGPKRDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRE-FAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILGLLLPPSILSLEFKNKDEMSYMPQDQEAYLQEKEEEEPEKPVKEKEEEDMEFTAMLGKVATDTSRKKDVEEVQSRHRLIPLGRKIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMD-LWPSPQEWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQ-EYWNITDLMAILIFSVGMVLRL-------QEPPFMSY--GRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPNEDPSWMLARNIFFMPYWMIYGEVFADQI 1033

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm2 (transient receptor potential cation channel subfamily M member 2 [Source:NCBI gene;Acc:101170060])

HSP 1 Score: 285.034 bits (728), Expect = 3.737e-78
Identity = 267/987 (27.05%), Postives = 464/987 (47.01%), Query Frame = 3

Query:  240 EKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKI-PYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKE----PIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDH--DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTT-TTLEKLYEDCPRSFNLKRTIFHFLGRN---FSNG--LGDVKDLLTKIFG---------YYEDQCAMCDEEI----------IHPFQE---------LFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNIN--LFQCILC-IFLP-----FLIYRRS--FDNSYVIHESKKK-----DDTSNKGYFTNSGNWPL----KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQF----TIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNN-WNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDY-PYWAIFGEITLN 2999
            E+  L  ++K+  +  +C  F +   E       C CG  K  H  + I P + V + W+ H     VPT +FG+I+F G   T  K   + R+S E + + +  L+ + W++    L ISV GG KNF +K   + +F++GLIK  +TT A I+T G N G+ + VG A+++    L +  +G   +  +G+A WG + N++ L + +G      ++++        L+KNHTH+L VD+     Y      + R  LEK +S +   K+     IPVV +++EG           +K   P VI  GTGR +D++     ++   P++Q+    +  L E +     KK  + +V       E    I++I+   +L+T+F V ED   D+++AIL +L+K    +    L+   +QL L + WNRVDIAK +IF+     S  +    +  +++  K +FV L L+NG  +  FL    TL  LY + P    L++       +     SN   L  V D +  + G         Y E +  M  E++            P  E         +F+W+VL  N + A   WE+ ++S+C AL AT+I K L      D    E + N   ++E  AI +  EC++ D+E A  ++   +  WGG T L +A KAED++F++    Q  +   W    +++  + + ++C +F P     FL +R    F       E+ KK      +T       ++ + PL    +LV  Y +PQ KF      +++  ++F   +  G+  M F    ++ E+L  +++  +  E+F ++F   ++  G +IK      + WN +D+L ++L  + +  R              ++   K +  +    F LR + + ++ + LGPKI+++ +M+  L F++ ++ I ++AYG+  QG      D  L+ +     Y PY  IFG    N
Sbjct:   26 ERCALSCWMKQNINKKECALFQKGPSE-----EICKCGYSKEAHNVEAIKPEDFVGETWNKHRHVLDVPTNAFGEIQFDGLQQTTAK---YARVSSETSPEVLYDLLTEQWHLLPPNLLISVTGGAKNFNLKPHLRNMFHRGLIKVAQTTGAWIITGGTNAGVMKHVGQAVRD--YSLSNSIQGQ--IVAIGVATWGVIHNREALINEEGCFPALYMTDKTSQGRLSCLDKNHTHFLLVDDGTHGHYGVE--IELRTCLEKCISGKQLGKKDSSVTIPVVCVVLEGGPGTLNTIFNAMKNGTPCVIFEGTGRIADVIA----QVSGLPLQQITITLIHQLMEKFFGQEYKKFTELSVI------EWTKKIQDIVRMSHLLTIFRVTEDSHGDVDVAILKALLKASRSSETLTLDCWKTQLELAVAWNRVDIAKTEIFTEDSLWSSADLHQAMFSALVGNKPQFVTLLLENGMSLRKFLQNEETLCNLYREMPSCIFLRKLAKRVHSKADLVDSNNITLTHVSDEVRHLLGNATRHIYPPYVEQRYCMSAEDLSLSLSKNNGAPRPAGEVAQRDASSDVFLWAVLQNNRDLAEIAWEQCQDSICAALAATRILKKLAGGES-DAEEAEEMLNQASHYEEHAIGVFSECYNTDEERALKLLVHVSNFWGGTTSLWLALKAEDKRFVALSGVQAFMTRVWCGELSVDNHILRVLICMLFFPLIYTGFLAFRHDELFQKEAKKQEAMKKVKRVTGNTHGAQSLGSAPDKPLSCWDRLVSLYGSPQVKF-----YWNIVSYFFFLNLFAGVLMMDFHATPSVPELLLYVWVFSLVCEEFRQLF-CNSDGFGFKIKAKLYITDLWNILDVLSILLFLLGLAFRL----------TSELFYAGKIVLCIDFVVFCLRLMAIFTISQTLGPKIIIVRRMMKDLFFFMFLLSIWVVAYGVAKQGILI-HNDTRLDWIFRGAIYEPYLIIFGNFPEN 970

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm2 (transient receptor potential cation channel subfamily M member 2 [Source:NCBI gene;Acc:101170060])

HSP 1 Score: 284.648 bits (727), Expect = 5.286e-78
Identity = 267/987 (27.05%), Postives = 464/987 (47.01%), Query Frame = 3

Query:  240 EKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKI-PYNKVND-WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKE----PIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDH--DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTT-TTLEKLYEDCPRSFNLKRTIFHFLGRN---FSNG--LGDVKDLLTKIFG---------YYEDQCAMCDEEI----------IHPFQE---------LFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNIN--LFQCILC-IFLP-----FLIYRRS--FDNSYVIHESKKK-----DDTSNKGYFTNSGNWPL----KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQF----TIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNN-WNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDY-PYWAIFGEITLN 2999
            E+  L  ++K+  +  +C  F +   E       C CG  K  H  + I P + V + W+ H     VPT +FG+I+F G   T  K   + R+S E + + +  L+ + W++    L ISV GG KNF +K   + +F++GLIK  +TT A I+T G N G+ + VG A+++    L +  +G   +  +G+A WG + N++ L + +G      ++++        L+KNHTH+L VD+     Y      + R  LEK +S +   K+     IPVV +++EG           +K   P VI  GTGR +D++     ++   P++Q+    +  L E +     KK  + +V       E    I++I+   +L+T+F V ED   D+++AIL +L+K    +    L+   +QL L + WNRVDIAK +IF+     S  +    +  +++  K +FV L L+NG  +  FL    TL  LY + P    L++       +     SN   L  V D +  + G         Y E +  M  E++            P  E         +F+W+VL  N + A   WE+ ++S+C AL AT+I K L      D    E + N   ++E  AI +  EC++ D+E A  ++   +  WGG T L +A KAED++F++    Q  +   W    +++  + + ++C +F P     FL +R    F       E+ KK      +T       ++ + PL    +LV  Y +PQ KF      +++  ++F   +  G+  M F    ++ E+L  +++  +  E+F ++F   ++  G +IK      + WN +D+L ++L  + +  R              ++   K +  +    F LR + + ++ + LGPKI+++ +M+  L F++ ++ I ++AYG+  QG      D  L+ +     Y PY  IFG    N
Sbjct:   26 ERCALSCWMKQNINKKECALFQKGPSE-----EICKCGYSKEAHNVEAIKPEDFVGETWNKHRHVLDVPTNAFGEIQFDGLQQTTAK---YARVSSETSPEVLYDLLTEQWHLLPPNLLISVTGGAKNFNLKPHLRNMFHRGLIKVAQTTGAWIITGGTNAGVMKHVGQAVRD--YSLSNSIQGQ--IVAIGVATWGVIHNREALINEEGCFPALYMTDKTSQGRLSCLDKNHTHFLLVDDGTHGHY--GVEIELRTCLEKCISGKQLGKKDSSVTIPVVCVVLEGGPGTLNTIFNAMKNGTPCVIFEGTGRIADVIA----QVSGLPLQQITITLIHQLMEKFFGQEYKKFTELSVI------EWTKKIQDIVRMSHLLTIFRVTEDSHGDVDVAILKALLKASRSSETLTLDCWKTQLELAVAWNRVDIAKTEIFTEDSLWSSADLHQAMFSALVGNKPQFVTLLLENGMSLRKFLQNEETLCNLYREMPSCIFLRKLAKRVHSKADLVDSNNITLTHVSDEVRHLLGNATRHIYPPYVEQRYCMSAEDLSLSLSKNNGAPRPAGEVAQRDASSDVFLWAVLQNNRDLAEIAWEQCQDSICAALAATRILKKLAGGES-DAEEAEEMLNQASHYEEHAIGVFSECYNTDEERALKLLVHVSNFWGGTTSLWLALKAEDKRFVALSGVQAFMTRVWCGELSVDNHILRVLICMLFFPLIYTGFLAFRHDELFQKEAKKQEAMKKVKRVTGNTHGAQSLGSAPDKPLSCWDRLVSLYGSPQVKF-----YWNIVSYFFFLNLFAGVLMMDFHATPSVPELLLYVWVFSLVCEEFRQLF-CNSDGFGFKIKAKLYITDLWNILDVLSILLFLLGLAFRL----------TSELFYAGKIVLCIDFVVFCLRLMAIFTISQTLGPKIIIVRRMMKDLFFFMFLLSIWVVAYGVAKQGILI-HNDTRLDWIFRGAIYEPYLIIFGNFPEN 970

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm3 (transient receptor potential cation channel subfamily M member 3 [Source:NCBI gene;Acc:100533512])

HSP 1 Score: 254.603 bits (649), Expect = 3.338e-68
Identity = 221/805 (27.45%), Postives = 374/805 (46.46%), Query Frame = 3

Query:  102 IKMNKTVSTTGDS--FSQNELFAQAVHQARF-----RLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH----------KKDKIPYNKVND-----WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYK-VSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-FLKESIING----KYEFVELFLQNGAVMNDFLTTTTLEK-----------LYE--------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED------------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTW 2204
            ++ ++  ST  DS   S      ++  + RF     RL+    ++      + +    K +I++ F   +C   +  +K+      +C CG L  +H          + DK      ND     WSI    +  PT++FG IEF G   +N  +  +VR+S++   D ++ LM   W +++  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   K  +  Y+ +SN   L++   LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L    +  ++  I          + E  R+ L   +      +  +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +  L++++++     + +FV+L ++NG  ++ FLT + LE+           LY         + P  + +                          RT++H       N  G  +    K+ G  +D                     + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N ++ F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W
Sbjct:   13 LRRDRAFSTRDDSSVASGTSGPGRSTTRGRFSESWKRLSSRGGSTKRGALNSQQPPAQKSWIERAFSKRECVHIIVSAKD----PHRCCCGRLIGQHVGLPPGISSSQNDKAERMAKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSYDTKPDLLLHLMTKEWQLDLPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDLV-GKDVVRPYQTMSNP--LSKLTVLNSLHSHFILADNGTTGKYGAE--VRLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGI----------INESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSVHRFLTLSRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRE-FAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMW 770

HSP 2 Score: 75.8702 bits (185), Expect = 3.206e-13
Identity = 71/225 (31.56%), Postives = 121/225 (53.78%), Query Frame = 3

Query: 2370 KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQLICLGVMTKQQIII 3044
            K+ +FY AP  KF  H+LA+   +  F+Y+VL  M  +  +  E + I Y+    IEK  E+   +  K+  ++K W     WN  D++ +++ ++ M+LR             M Y   + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q    P  D S     NI   PYW I+GE+  +Q+  +     QQ +I
Sbjct:  882 KIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMD-LWPSPQEWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQ-EYWNITDLMAILIFSVGMVLRL-------QEPPFMSY--GRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPNEDPSWMLARNIFFMPYWMIYGEVFADQIDHMHSRKFQQRLI 1095

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Match: trpm3 (transient receptor potential cation channel subfamily M member 3 [Source:NCBI gene;Acc:100533512])

HSP 1 Score: 254.218 bits (648), Expect = 4.913e-68
Identity = 211/747 (28.25%), Postives = 351/747 (46.99%), Query Frame = 3

Query:  255 KGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEH----------KKDKIPYNKVND-----WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYK-VSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQR---TKNKEPIPVVLLLIEGEYDVFFEASKRIKEN--VPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDV-KEDH-DLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWAL-----FLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEK-----------LYE--------DCPRSFNLK-------------------------RTIFHFLGRNFSNGLGDVKDLLTKIFGYYED------------------QCAMCDEEIIH---PFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLM----EMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTW 2204
            K +I++ F   +C   +  +K+      +C CG L  +H          + DK      ND     WSI    +  PT++FG IEF G   +N  +  +VR+S++   D ++ LM   W +++  L ISV GG +NF+++ K K +F +GLIKA  TT A I T G+N G+ R VGDA++    D   K++G   +C +GIAPWG V+N++ L   K  +  Y+ +SN   L++   LN  H+H++  D      Y        R  LEK +S +   T+  + +PVV L++EG  +V     + +++   VP+V+C G+GRASD+L    +  ++  I          + E  R+ L   +      +  +       + E + K+ LIT+F +  E H D++LAIL +L+K  + ++         QLSL L WNRVDIA+ +IF     +  + W +      + ++++  + +FV+L ++NG  ++ FLT + LE+           LY         + P  + +                          RT++H       N  G  +    K+ G  +D                     + D EI H   PF EL +W+VLM+  + A +FW+  EE++  ALVA K+ K +     E   +D    E   N ++ F  LA++LL++ +  D++ A  ++  E   W   TCL++A  A+ + FI+    Q  L   W
Sbjct:   33 KSWIERAFSKRECVHIIVSAKD----PHRCCCGRLIGQHVGLPPGISSSQNDKAERMAKNDSLSEKWSISKHTQLSPTDAFGTIEFQGGGHSNKAM--YVRVSYDTKPDLLLHLMTKEWQLDLPKLLISVHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDALK----DHASKSRGK--ICTIGIAPWGIVENQEDLV-GKDVVRPYQTMSNP--LSKLTVLNSLHSHFILADNGTTGKYGAE--VRLRRQLEKHISLQKINTRIGQGVPVVALIVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRASDILAFGHKYSEEGGI----------INESLRDQLLVTIQKTFTYSRTQAQHLFIILMECMKKKELITVFRMGSEGHQDIDLAILTALLKGANASA-------PDQLSLALAWNRVDIARSQIF-----IYGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGVSVHRFLTLSRLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYH-------NLFGPKRPKALKLLGMEDDMPIRRGRQKTTRKREEEVDIDLDDPEINHFPFPFHELMVWAVLMKRQKMALFFWQHGEEAMAKALVACKLCKAMAHEASENDMVDDISQELNHNSRE-FAQLAVELLDQSYKQDEQMAMKLLTYELKNWSNATCLQLAVAAKHRDFIAHTCSQMLLTDMW 732

HSP 2 Score: 75.8702 bits (185), Expect = 2.718e-13
Identity = 71/225 (31.56%), Postives = 121/225 (53.78%), Query Frame = 3

Query: 2370 KLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQLICLGVMTKQQIII 3044
            K+ +FY AP  KF  H+LA+   +  F+Y+VL  M  +  +  E + I Y+    IEK  E+   +  K+  ++K W     WN  D++ +++ ++ M+LR             M Y   + IY + + Y+Y+R L +  V+K LGP ++MI KM+  +M+++IIML++L+++G+  Q    P  D S     NI   PYW I+GE+  +Q+  +     QQ +I
Sbjct:  844 KIYEFYNAPIVKFWFHTLAYVGYLMLFNYIVLVKMD-LWPSPQEWIVIAYIFTNGIEKMREILMSEPGKLLQKVKVWLQ-EYWNITDLMAILIFSVGMVLRL-------QEPPFMSY--GRVIYCINIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFGVARQAILNPNEDPSWMLARNIFFMPYWMIYGEVFADQIDHMHSRKFQQRLI 1057

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064637.1 (SMESG000064637.1)

HSP 1 Score: 1592.02 bits (4121), Expect = 0.000e+0
Identity = 770/770 (100.00%), Postives = 770/770 (100.00%), Query Frame = 3

Query:  108 MNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIH 2417
            MNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIH
Sbjct:    1 MNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIH 770

HSP 2 Score: 624.394 bits (1609), Expect = 0.000e+0
Identity = 340/340 (100.00%), Postives = 340/340 (100.00%), Query Frame = 2

Query: 3008 LPWCDDKTTNYNISNECPELNYFVPVXXXXXXXXXXXXXXXXXXXVFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSIFAHAFDFFYSLCGNQCEKTEENEKNLDTLSRDSQITFSPPKKMKSFNFRKLAIPLESEIDKLVKYFENNSQXXXXXXXXXXXXQLIESGMSRLESRLKAMSTIIKSIESKFEDSENPGNHNSAEMGNCYYPTLDISEFEVQNPTTFIEEDIINTNKEIVSLIHDLRTGQLSVSAPSSNANVRSSFLIPRIIVDENCDNNFSDPNSDLGGNKLKNWVTELINIDSETVLEVQNLQKKLCDFQDHVVESFTKIESFL 4027
            LPWCDDKTTNYNISNECPELNYFVPVLTAIYIFIAAILLLNILTAVFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSIFAHAFDFFYSLCGNQCEKTEENEKNLDTLSRDSQITFSPPKKMKSFNFRKLAIPLESEIDKLVKYFENNSQKCVVKELVEEKEQLIESGMSRLESRLKAMSTIIKSIESKFEDSENPGNHNSAEMGNCYYPTLDISEFEVQNPTTFIEEDIINTNKEIVSLIHDLRTGQLSVSAPSSNANVRSSFLIPRIIVDENCDNNFSDPNSDLGGNKLKNWVTELINIDSETVLEVQNLQKKLCDFQDHVVESFTKIESFL
Sbjct:  899 LPWCDDKTTNYNISNECPELNYFVPVLTAIYIFIAAILLLNILTAVFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSIFAHAFDFFYSLCGNQCEKTEENEKNLDTLSRDSQITFSPPKKMKSFNFRKLAIPLESEIDKLVKYFENNSQKCVVKELVEEKEQLIESGMSRLESRLKAMSTIIKSIESKFEDSENPGNHNSAEMGNCYYPTLDISEFEVQNPTTFIEEDIINTNKEIVSLIHDLRTGQLSVSAPSSNANVRSSFLIPRIIVDENCDNNFSDPNSDLGGNKLKNWVTELINIDSETVLEVQNLQKKLCDFQDHVVESFTKIESFL 1238

HSP 3 Score: 207.608 bits (527), Expect = 0.000e+0
Identity = 119/122 (97.54%), Postives = 121/122 (99.18%), Query Frame = 3

Query: 2649 SAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQLICL 3014
            +AMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKMLYQLMFYIIIMLIILLAYGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQL+ L
Sbjct:  778 TAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKMLYQLMFYIIIMLIILLAYGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQLVYL 899

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064637.1 (SMESG000064637.1)

HSP 1 Score: 1589.32 bits (4114), Expect = 0.000e+0
Identity = 770/770 (100.00%), Postives = 770/770 (100.00%), Query Frame = 3

Query:  108 MNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIH 2417
            MNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIH
Sbjct:    1 MNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIH 770

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064622.1 (SMESG000064622.1)

HSP 1 Score: 1023.08 bits (2644), Expect = 0.000e+0
Identity = 524/958 (54.70%), Postives = 688/958 (71.82%), Query Frame = 3

Query:  144 SQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKY--PIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRS-FDNSYVIHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEITLNQLI 3008
            +QNE +   + QAR ++ +  + SNV+F  NDEK   + +I  KF S++CR+F    KE+ +K +KC CGE+K  HK++KIPY     WS   C E +PT SFGKIEF GED+TN+KLT+FVR+S+ D LDD++ L+F+ W I  GTLCISV+GGT +FKM  KEK IF QGLIKA  TTNALI+T GLN GIT  +GDAIQ  Q  LYDK K NN + CLGIAPWG+VKN+KILE AKG  + Y VSNE+   +P+SLNKNHTHY+F D+  R   +  K   FR+ALE K+SQ+  ++  IPVVLL++EG +D+F EAS+R+KE V IV+C GTG+ASD++GEAFREMQ+     K +R DGV MLPE ++N LK+KLI++++S   +V+EA+  IE+II  E LIT+FD+K   DL+ AILYSLIKRMD   DS  N LSSQLSLCL WNRVDI KDKIFSG +SLS + WA FLK+SII GK +F+ELFL+N + + DFLT   L++LYE CP+S N ++T    +GR FS GL DVK+LL+K+ G+YE  C+  D  I HPFQELF+W+VLME  +CA +FW K +ESL LALVAT+IYK     S  DT R ETL  WK+YFENLA+KL+EECHD DQE AAY+IEK+N  WGG +CLE+A K+ D KF+S +VCQN                CILCI  PFLI +R+ F   +   +S+   D +     T+  +   KL +FYLAPQTKFCIHS  F   + YFSYVVL+GMKRMQ TIHEI+F+IYL+ M ++KF E+F+ +++++  RIKYWW FN+WNKVD+++++ + +AM+LR+ L +     D V+++R SKTIYSLIVG FYL+ LRL++ HK LGPKI M+SK++ +L+ +  I+LI LL+YG+T Q  Y+PQRDFS   L NI+DYPY+ +FG + L   +
Sbjct:   11 TQNEDYTVTIRQARCKINESYRESNVHFAENDEKMQYRNYINAKFQSVECRYFSVAIKEIDDKNSKCSCGEIKKSHKENKIPYGPRESWSEGDCMEMLPTYSFGKIEFTGEDITNSKLTDFVRVSYRDKLDDIVDLIFNKWKITAGTLCISVIGGTIDFKMHHKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKNRKILEFAKGRTVHYNVSNEVEKHQPISLNKNHTHYIFFDDGYRLQMTKKKVGYFRQALENKISQKQGDRVGIPVVLLIVEGGHDIFIEASRRVKEKVSIVVCEGTGKASDIIGEAFREMQRICSRHKMIRSDGVAMLPESFKNVLKRKLIEQDISELHQVDEAIKCIEDIIKNELLITVFDIKSHEDLDFAILYSLIKRMDLLCDSNQNPLSSQLSLCLTWNRVDIVKDKIFSGDISLSNDEWAAFLKDSIITGKVKFIELFLENVSNIQDFLTANILKELYETCPKSTNFRKTFLRLIGRPFSKGLNDVKELLSKMIGFYEYPCSEND-SIKHPFQELFLWAVLMEKQKCAKFFWGKCDESLFLALVATRIYKYHQRTSLRDTDRSETLETWKNYFENLAVKLIEECHDIDQEVAAYLIEKKNENWGGISCLELASKSTDLKFMSNIVCQN----------------CILCIIFPFLISKRTEFTKDFKTCQSESFPDFNEDNCRTSISS---KLRRFYLAPQTKFCIHSFTFISFIIYFSYVVLYGMKRMQVTIHEIMFMIYLVLMILDKFVEIFKSRSDRIYGRIKYWWTFNHWNKVDMIIIVFAIVAMVLRYQLAINGVYTDKVVMFRWSKTIYSLIVGSFYLKILRLLACHKKLGPKIFMMSKIIKELLIFSTIILIFLLSYGVTSQAGYYPQRDFSWIALSNILDYPYYTMFGVLNLGNTV 948

HSP 2 Score: 109.768 bits (273), Expect = 7.973e-24
Identity = 80/188 (42.55%), Postives = 118/188 (62.77%), Query Frame = 2

Query: 2999 SIDLPWCDDKTTNYNISNECPELNYFVPVXXXXXXXXXXXXXXXXXXXVFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSIFAHAFDFFYSLC--GNQCEKTEENEKNLDTLSRDSQITFSPPKKMKSFNFRKLA-IPLESEIDKLVKYFENNSQXXXXXXXXXXXXQLIESGMSRLESRL 3553
            ++   WC+  +TNY +SNECPE N+ +P+L A Y+ I  ILLLNIL A  +YI Q IHRNSI IWK++M+SL++EY  KP+ P+PFS F + +    + C    +C     N K  +    +S++    P   K       + I  +S+++KL+KYFEN SQK V+K +  EK++ I+SG+SR+E RL
Sbjct:  947 TVYFTWCN-ASTNYEVSNECPENNFLIPILFAGYVIIINILLLNILIATSSYICQDIHRNSIVIWKYSMYSLILEYNDKPILPMPFSTFVYIYQVL-AFCYQKGRCYNL-SNSKKFEITKHNSKLHIDKPMAFKHDTLNIFSNIKSDSDLNKLIKYFENYSQKFVIKNIAIEKQKSIKSGISRMEIRL 1131

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064632.1 (SMESG000064632.1)

HSP 1 Score: 939.488 bits (2427), Expect = 0.000e+0
Identity = 488/956 (51.05%), Postives = 663/956 (69.35%), Query Frame = 3

Query:  150 NELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQ--LRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRSFDNSYV-------IHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            N+ F+ ++ QARF++TD ++ S++ F+ NDEK   + F+K  FHSI+CR F    + L +   KC+CGE K  HK DK P++  + W  +   E + T+SFGKIEF GED+TNTKLT+FVR+S+ D LDD+++L+F+ WNI +GTLCISV+GGT +FKM+KKEK IF QGLIKA  TTNALI+T GLN GIT  +GDAIQ  Q  LYDK K NN + CLGIAPWG+VK + ILE AKG  + Y VSNE+   +PVSLNK+HTHY+FVD+  R   S  K + FR+ALE K+SQ+   +  IPVVLL++EG ++V  E S                RAS++LGE F+E+     K+   R     +  E YR +LK KLI++N+    +V+E +  IEEI+ KE+LITLF +K   DL+ AIL+SLIKRMDF  D + N LSSQLSLCL WNR+DI KDKIF G +SLS   W  F KESI+ G+ +F+ELFL+N + ++DFLTT  L+ LY+  P+S N ++T    +GR+FS GL + K+L+ K+ G    Q  M ++  +HPFQELF+WSVLME ++CA +FW K +++LCLALVAT+IYKCL   S  DT R  TL+ WK+ FENLA+KL+EECHD DQETAAY+IEKE   + G TCLE+A K+++ KF+S +VCQNS+DFTWRAGF I+ ++CILCI  PFLI      N Y        +H +++  D        +   +  KL +FY+APQTKF IHS+ F+  + YFSYVVL+GM+RM  + HE +F+ YL+ +  E   EMFQ ++  + DR+KYWW FN  NK+D ++++L+  AM LR+PL     + DI++IYRCSKTIYSLIVG  Y+RFLRL++ HK LGPK++M+++++ QLM Y+II++I L +YG+T Q  Y+ QRDFS + L N+  YPY+ + G I
Sbjct:   13 NDEFSASIRQARFKITDSNRGSHIRFSENDEKALYRKFVKSNFHSIECRKFSSLEEILDHNNAKCMCGEAKKNHKIDKTPFSLCDPWKENESMEVISTDSFGKIEFFGEDITNTKLTDFVRVSYNDKLDDILELLFNKWNINVGTLCISVIGGTIDFKMRKKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKKRNILESAKGRTVHYNVSNEVEQNQPVSLNKHHTHYIFVDDGYRLQMSRKKVAYFRQALENKISQKLGERAAIPVVLLIVEGGHEVLVEGS----------------RASNILGEVFQEVSNSSWKRERTRSGDTSVFSENYRKALKTKLIEQNICELHQVDEDVKCIEEIVKKEFLITLFYIKSHQDLDFAILHSLIKRMDFLCDPRYNPLSSQLSLCLIWNRIDIVKDKIFLGDISLSNAEWIAFFKESIMKGRIDFIELFLENVSNLHDFLTTEILDDLYKTYPKSNNFRKTFLILIGRSFSKGLSEAKELVFKMIGVNRKQLKMRNDYSLHPFQELFLWSVLMEKNKCARFFWGKCDDALCLALVATRIYKCLRGTSVRDTDRQVTLTLWKESFENLAVKLIEECHDIDQETAAYLIEKEIPIFEGITCLELANKSKNLKFMSNIVCQNSIDFTWRAGFTISFYECILCILFPFLIL---MQNKYTKDLKPLKLHRAQECQDYIE---VRSMPYYKAKLKRFYMAPQTKFVIHSITFTSFLLYFSYVVLYGMRRMTLSTHETIFMSYLVILIFESIIEMFQSRSYSIFDRMKYWWKFNYCNKLDAIIILLAISAMALRYPLAYYPIDADIIIIYRCSKTIYSLIVGMLYIRFLRLLTRHKKLGPKMMMMTELVKQLMIYLIIIVIFLASYGVTSQAGYYLQRDFSWSALANLFQYPYYTMLGVI 946

HSP 2 Score: 72.0182 bits (175), Expect = 3.227e-12
Identity = 53/139 (38.13%), Postives = 80/139 (57.55%), Query Frame = 2

Query: 2948 EYNGLPVLGYIWGDYIESIDLPWCDDKTTNYNISNECPELNYFVPVXXXXXXXXXXXXXXXXXXXVFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSIFAHAFDFFYSLCGNQCEKTEENEKNLDTLSRDSQ 3364
            +Y    +LG I+  Y  ++ L WCD    N   S +CPE N  +P+L A ++ I+ IL++NIL A    + + IH++SI+IWK+  +SL++EY  KP+ PLPFS+  H ++     CG   E    N KN D + R  Q
Sbjct:  936 QYPYYTMLGVIFSKY--NVYLSWCDP-AMNTTESKDCPEQNVVMPILFAAFVMISNILIMNILVATNCELCENIHKDSIDIWKYNKYSLLLEYEKKPIIPLPFSMIIHIYNILTDRCG---ESECYNLKNKDEMMRYEQ 1068

[Close]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Match: SMESG000064632.1 (SMESG000064632.1)

HSP 1 Score: 939.102 bits (2426), Expect = 0.000e+0
Identity = 488/956 (51.05%), Postives = 663/956 (69.35%), Query Frame = 3

Query:  150 NELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLKGFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVNDWSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMFDYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSGLNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHAKGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREALEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGRASDLLGEAFREMQKYPIKQ--LRPDGVPMLPEMYRNSLKKKLIDKNVSNPDKVNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLNTLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFVELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGDVKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKTEESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECHDADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWRAGFNINLFQCILCIFLPFLIYRRSFDNSYV-------IHESKKKDDTSNKGYFTNSGNWPLKLVQFYLAPQTKFCIHXXXXXXXXXXXXXXXXXGMKRMQFTIHEILFIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAMAMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLGPKIVMISKXXXXXXXXXXXXXXXXXXXGITMQGAYFPQRDFSLNTLPNIMDYPYWAIFGEI 2990
            N+ F+ ++ QARF++TD ++ S++ F+ NDEK   + F+K  FHSI+CR F    + L +   KC+CGE K  HK DK P++  + W  +   E + T+SFGKIEF GED+TNTKLT+FVR+S+ D LDD+++L+F+ WNI +GTLCISV+GGT +FKM+KKEK IF QGLIKA  TTNALI+T GLN GIT  +GDAIQ  Q  LYDK K NN + CLGIAPWG+VK + ILE AKG  + Y VSNE+   +PVSLNK+HTHY+FVD+  R   S  K + FR+ALE K+SQ+   +  IPVVLL++EG ++V  E S                RAS++LGE F+E+     K+   R     +  E YR +LK KLI++N+    +V+E +  IEEI+ KE+LITLF +K   DL+ AIL+SLIKRMDF  D + N LSSQLSLCL WNR+DI KDKIF G +SLS   W  F KESI+ G+ +F+ELFL+N + ++DFLTT  L+ LY+  P+S N ++T    +GR+FS GL + K+L+ K+ G    Q  M ++  +HPFQELF+WSVLME ++CA +FW K +++LCLALVAT+IYKCL   S  DT R  TL+ WK+ FENLA+KL+EECHD DQETAAY+IEKE   + G TCLE+A K+++ KF+S +VCQNS+DFTWRAGF I+ ++CILCI  PFLI      N Y        +H +++  D        +   +  KL +FY+APQTKF IHS+ F+  + YFSYVVL+GM+RM  + HE +F+ YL+ +  E   EMFQ ++  + DR+KYWW FN  NK+D ++++L+  AM LR+PL     + DI++IYRCSKTIYSLIVG  Y+RFLRL++ HK LGPK++M+++++ QLM Y+II++I L +YG+T Q  Y+ QRDFS + L N+  YPY+ + G I
Sbjct:   13 NDEFSASIRQARFKITDSNRGSHIRFSENDEKALYRKFVKSNFHSIECRKFSSLEEILDHNNAKCMCGEAKKNHKIDKTPFSLCDPWKENESMEVISTDSFGKIEFFGEDITNTKLTDFVRVSYNDKLDDILELLFNKWNINVGTLCISVIGGTIDFKMRKKEKNIFCQGLIKAAITTNALIITPGLNKGITSVIGDAIQYSQSYLYDKMKHNNFISCLGIAPWGYVKKRNILESAKGRTVHYNVSNEVEQNQPVSLNKHHTHYIFVDDGYRLQMSRKKVAYFRQALENKISQKLGERAAIPVVLLIVEGGHEVLVEGS----------------RASNILGEVFQEVSNSSWKRERTRSGDTSVFSENYRKALKTKLIEQNICELHQVDEDVKCIEEIVKKEFLITLFYIKSHQDLDFAILHSLIKRMDFLCDPRYNPLSSQLSLCLIWNRIDIVKDKIFLGDISLSNAEWIAFFKESIMKGRIDFIELFLENVSNLHDFLTTEILDDLYKTYPKSNNFRKTFLILIGRSFSKGLSEAKELVFKMIGVNRKQLKMRNDYSLHPFQELFLWSVLMEKNKCARFFWGKCDDALCLALVATRIYKCLRGTSVRDTDRQVTLTLWKESFENLAVKLIEECHDIDQETAAYLIEKEIPIFEGITCLELANKSKNLKFMSNIVCQNSIDFTWRAGFTISFYECILCILFPFLIL---MQNKYTKDLKPLKLHRAQECQDYIE---VRSMPYYKAKLKRFYMAPQTKFVIHSITFTSFLLYFSYVVLYGMRRMTLSTHETIFMSYLVILIFESIIEMFQSRSYSIFDRMKYWWKFNYCNKLDAIIILLAISAMALRYPLAYYPIDADIIIIYRCSKTIYSLIVGMLYIRFLRLLTRHKKLGPKMMMMTELVKQLMIYLIIIVIFLASYGVTSQAGYYLQRDFSWSALANLFQYPYYTMLGVI 946

HSP 2 Score: 68.9366 bits (167), Expect = 2.241e-11
Identity = 46/118 (38.98%), Postives = 72/118 (61.02%), Query Frame = 2

Query: 2948 EYNGLPVLGYIWGDYIESIDLPWCDDKTTNYNISNECPELNYFVPVXXXXXXXXXXXXXXXXXXXVFNYIFQRIHRNSIEIWKFTMFSLVMEYYTKPLFPLPFSIFAHAFDFFYSLCG 3301
            +Y    +LG I+  Y  ++ L WCD    N   S +CPE N  +P+L A ++ I+ IL++NIL A    + + IH++SI+IWK+  +SL++EY  KP+ PLPFS+  H ++     CG
Sbjct:  936 QYPYYTMLGVIFSKY--NVYLSWCDP-AMNTTESKDCPEQNVVMPILFAAFVMISNILIMNILVATNCELCENIHKDSIDIWKYNKYSLLLEYEKKPIIPLPFSMIIHIYNILTDRCG 1050

The following BLAST results are available for this feature:

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Sea Lamprey
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Yeast
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Nematostella
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TRPM3	1.799e-90	27.77	transient receptor potential cation channel subfam...	[more]
TRPM3	3.195e-89	27.86	transient receptor potential cation channel subfam...	[more]
TRPM3	1.936e-80	28.34	transient receptor potential cation channel subfam...	[more]
TRPM3	4.981e-78	28.12	transient receptor potential cation channel subfam...	[more]
TRPM3	4.981e-78	28.12	transient receptor potential cation channel subfam...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gtl-2	4.858e-60	23.71	Gon-Two Like (TRP subfamily) [Source:UniProtKB/Tr...	[more]
gon-2	9.553e-44	26.15	Transient receptor potential channel [Source:UniP...	[more]
gon-2	1.022e-43	26.15	Transient receptor potential channel [Source:UniP...	[more]
gon-2	1.148e-43	26.15	Transient receptor potential channel [Source:UniP...	[more]
gtl-1	8.758e-43	26.96	GTL-1; Gon-Two Like (TRP subfamily) [Source:UniPr...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Trpm	1.595e-72	26.30	gene:FBgn0265194 transcript:FBtr0339075	[more]
Trpm	2.240e-72	26.53	gene:FBgn0265194 transcript:FBtr0339082	[more]
Trpm	2.417e-71	26.52	gene:FBgn0265194 transcript:FBtr0339074	[more]
Trpm	7.576e-71	26.53	gene:FBgn0265194 transcript:FBtr0339079	[more]
Trpm	9.314e-71	26.59	gene:FBgn0265194 transcript:FBtr0339077	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trpm2	1.924e-76	25.94	transient receptor potential cation channel, subfa...	[more]
trpm3	4.669e-70	28.65	transient receptor potential cation channel, subfa...	[more]
hrc	2.497e-65	25.08	histidine rich calcium binding protein [Source:ZFI...	[more]
trpm4b.2	1.314e-63	24.43	transient receptor potential cation channel, subfa...	[more]
trpm5	1.444e-60	27.83	transient receptor potential cation channel, subfa...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
aldh3a2	3.079e-90	28.61	aldehyde dehydrogenase 3 family member A2 [Source:...	[more]
TRPM1	3.368e-90	28.47	transient receptor potential cation channel subfam...	[more]
aldh3a2	1.673e-89	28.74	aldehyde dehydrogenase 3 family member A2 [Source:...	[more]
aldh3a2	3.445e-89	27.97	aldehyde dehydrogenase 3 family member A2 [Source:...	[more]
TRPM1	2.592e-88	27.21	transient receptor potential cation channel subfam...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Trpm3	2.471e-90	28.23	transient receptor potential cation channel, subfa...	[more]
Trpm3	3.625e-90	28.23	transient receptor potential cation channel, subfa...	[more]
Trpm3	4.389e-89	27.86	transient receptor potential cation channel, subfa...	[more]
Trpm3	4.400e-89	27.86	transient receptor potential cation channel, subfa...	[more]
Trpm3	1.073e-85	27.75	transient receptor potential cation channel, subfa...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9HCF6\|TRPM3_HUMAN	3.588e-85	27.22	Transient receptor potential cation channel subfam...	[more]
sp\|A7T1N0\|TMP2L_NEMVE	1.663e-81	27.86	Transient receptor potential cation channel subfam...	[more]
sp\|A0A0R4IMY7\|TRPM2_DANRE	1.452e-75	25.94	Transient receptor potential cation channel subfam...	[more]
sp\|Q91YD4\|TRPM2_MOUSE	2.781e-71	25.57	Transient receptor potential cation channel subfam...	[more]
sp\|E9PTA2\|TRPM2_RAT	3.992e-71	25.46	Transient receptor potential cation channel subfam...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5K4FE95	2.321e-165	35.67	Uncharacterized protein OS=Schistosoma mansoni OX=...	[more]
A0A267FX17	3.542e-159	35.19	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267E1J7	5.511e-159	35.19	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267FD75	1.834e-158	35.19	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A183AFB2	3.338e-149	34.29	LSDAT_euk domain-containing protein OS=Echinostoma...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trpm3	3.438e-74	28.11	transient receptor potential cation channel, subfa...	[more]
hrc	6.438e-67	24.74	transient receptor potential cation channel subfam...	[more]
trpm4a	1.236e-58	25.39	transient receptor potential cation channel subfam...	[more]
trpm4a	1.575e-58	25.39	transient receptor potential cation channel subfam...	[more]
trpm7	3.077e-55	30.71	transient receptor potential cation channel subfam...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
trpm7	6.204e-83	28.79	transient receptor potential cation channel, subfa...	[more]
trpm7	1.212e-75	27.27	transient receptor potential cation channel, subfa...	[more]
trpm2	8.554e-30	23.80	transient receptor potential cation channel, subfa...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO30135	6.818e-83	27.86	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47658	2.243e-50	30.88	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trpm3	7.012e-85	28.35	transient receptor potential cation channel subfam...	[more]
trpm2	3.737e-78	27.05	transient receptor potential cation channel subfam...	[more]
trpm2	5.286e-78	27.05	transient receptor potential cation channel subfam...	[more]
trpm3	3.338e-68	27.45	transient receptor potential cation channel subfam...	[more]
trpm3	4.913e-68	28.25	transient receptor potential cation channel subfam...	[more]

BLAST of Transient receptor potential cation channel subfamily M member 6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000064637.1	0.000e+0	100.00	SMESG000064637.1	[more]
SMESG000064637.1	0.000e+0	100.00	SMESG000064637.1	[more]
SMESG000064622.1	7.973e-24	54.70	SMESG000064622.1	[more]
SMESG000064632.1	3.227e-12	51.05	SMESG000064632.1	[more]
SMESG000064632.1	2.241e-11	51.05	SMESG000064632.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30005926 ID=SMED30005926|Name=Transient receptor potential cation channel subfamily M member 6|organism=Schmidtea mediterranea sexual|type=transcript|length=4027bp
TCTAATATAGATATAAAAGCTGATACATATTTAAATTATTCTTGTTTTCT
TGATTTACACCGACTTCATGAATTATATTAAGTTTATTAAAAATTGGTAA
TATCAAAATGAATAAAACAGTTTCCACTACTGGCGATTCTTTTTCACAGA
ATGAATTGTTCGCACAAGCCGTTCACCAAGCTCGATTCAGGCTGACGGAT
GGTAGCAAAAACAGCAACGTTAATTTTAATGCAAATGATGAAAAAAACCA
TTTAAAGGGTTTCATCAAGAAGAAATTTCATTCGATTGACTGCCGGTTTT
TTGTTGAAAAATCTAAAGAACTATCAAACAAACAAACAAAGTGCTTATGT
GGAGAGCTGAAATCAGAACATAAAAAAGATAAGATTCCTTACAATAAAGT
CAATGATTGGAGCATTCATTCGTGTTTTGAAACTGTTCCAACTGAAAGTT
TTGGTAAAATAGAATTTATTGGAGAAGATGTTACAAATACCAAATTAACA
GAATTTGTCCGTCTTAGCCATGAAGATAATTTAGATGATGTCATGAAGCT
CATGTTTGATTACTGGAATATAGAAATTGGTACTCTCTGTATTTCTGTCC
TTGGAGGCACAAAAAATTTTAAAATGAAGAAAAAAGAAAAATACATTTTC
TACCAAGGACTTATTAAAGCTGTCAAAACCACAAATGCACTGATTCTTAC
ATCTGGCTTGAATCTTGGAATTACTCGGTTCGTTGGTGATGCCATTCAAA
ATGGTCAATGCGATCTTTATGATAAAGCAAAAGGCAACAATTCTCTATGC
TGTCTAGGAATTGCACCATGGGGATTTGTGAAAAATAAAAAGATATTAGA
ACATGCCAAAGGGACAATAATTAAGTATAAGGTTTCTAACGAAATTCTTT
TAACCGAGCCTGTCTCCTTAAATAAAAATCACACTCATTACTTATTTGTT
GATGAACATGAACGGTTTGACTATTCTAATTCGAAAGCCAGTGATTTTAG
AGAGGCGCTTGAAAAGAAATTAAGCCAAAGAACAAAAAACAAAGAACCGA
TTCCAGTGGTTCTACTATTAATCGAAGGAGAGTATGATGTTTTCTTTGAG
GCAAGTAAACGAATCAAGGAAAATGTTCCAATTGTGATTTGTGTTGGCAC
TGGGAGAGCTTCCGACTTGCTCGGAGAAGCTTTCCGTGAAATGCAAAAAT
ACCCAATCAAACAACTTCGACCAGATGGTGTACCAATGCTCCCGGAAATG
TATCGTAATAGTTTAAAAAAGAAACTAATTGACAAAAATGTTTCTAATCC
TGACAAAGTGAATGAGGCATTAAATTACATTGAAGAAATAATTCATAAAG
AATATTTAATAACATTATTTGACGTAAAAGAGGATCATGATCTGGAACTT
GCCATTTTATATTCCCTAATCAAACGAATGGATTTCACTAGCGATTCCAA
GTTAAACACTTTGTCAAGTCAATTGTCACTTTGTTTGAAATGGAACAGAG
TTGACATTGCAAAAGATAAAATCTTTTCAGGAGTGGTTTCTCTTTCAAAA
GAAAATTGGGCGTTGTTTCTAAAAGAATCTATCATTAACGGGAAATATGA
ATTTGTTGAGTTATTTTTACAAAATGGCGCCGTAATGAATGATTTCTTAA
CAACTACTACTTTGGAAAAATTATATGAAGATTGTCCGAGGTCATTTAAC
CTAAAAAGAACTATTTTTCATTTTCTCGGGAGAAATTTTTCCAATGGATT
GGGAGATGTCAAAGATTTACTGACGAAAATTTTTGGATATTATGAAGATC
AGTGTGCTATGTGTGATGAAGAAATAATTCATCCATTTCAAGAATTGTTT
ATTTGGTCGGTACTTATGGAGAATCATGAATGTGCAAATTATTTTTGGGA
AAAAACTGAAGAATCATTGTGTTTGGCATTAGTTGCAACAAAGATCTATA
AATGTTTGATGGAAATGTCTCCTTTGGACACTTCTAGAATAGAAACTTTA
TCCAACTGGAAAGATTATTTTGAAAATTTAGCAATTAAGCTTCTAGAGGA
ATGTCATGATGCTGATCAGGAAACTGCAGCATACATCATTGAAAAGGAAA
ATATCACATGGGGCGGTTATACTTGCTTAGAAATAGCTTATAAAGCAGAA
GATCAAAAATTTATTAGTTGTATGGTTTGTCAGAATTCCCTTGATTTCAC
CTGGCGTGCTGGATTCAATATTAATCTTTTCCAATGTATTTTATGTATAT
TCTTGCCATTTCTCATTTACAGGAGATCCTTTGACAACAGTTATGTAATA
CATGAATCCAAGAAGAAGGATGATACATCGAATAAAGGTTATTTCACCAA
CAGTGGCAATTGGCCGTTGAAATTGGTACAATTCTATCTGGCTCCTCAAA
CTAAATTTTGCATTCACAGTCTCGCCTTCTCCGTGTCGGTCTTTTATTTT
TCTTATGTGGTTTTGTTTGGAATGAAACGGATGCAGTTTACGATCCACGA
AATACTTTTTATAATATATTTGATATGCATGAATATTGAAAAGTTTGCGG
AGATGTTTCAATACAAGACCAATAAAGTTGGAGACCGAATTAAATACTGG
TGGAATTTTAATAATTGGAATAAAGTTGATATTTTAATGGTCATTTTGTC
AGCAATGGCAATGATATTAAGGTTTCCTTTGCTCTTGAAAAATTGGAATG
GGGACATTGTTATGATTTATAGGTGTTCAAAAACAATATACAGTTTAATA
GTTGGTTATTTTTATCTACGATTTTTGCGGCTCATAAGCGTTCACAAAAA
CCTTGGCCCAAAAATAGTTATGATTTCAAAAATGTTATACCAACTTATGT
TTTACATAATCATTATGCTGATTATTCTGCTGGCTTACGGAATTACTATG
CAAGGAGCTTATTTTCCTCAAAGAGATTTTAGTCTGAATACTCTACCGAA
TATAATGGACTACCCGTACTGGGCTATATTTGGGGAGATTACATTGAATC
AATTGATTTGCCTTGGTGTGATGACAAAACAACAAATTATAATATTTCAA
ATGAATGCCCTGAACTCAACTATTTTGTTCCGGTTTTGACAGCTATATAT
ATTTTTATTGCAGCTATATTATTATTAAATATCCTGACTGCAGTTTTCAA
CTACATTTTTCAAAGAATTCACAGAAATTCGATAGAAATCTGGAAATTCA
CAATGTTTTCTTTGGTTATGGAATATTATACGAAACCGCTTTTTCCGCTG
CCTTTTTCTATATTTGCTCACGCGTTTGACTTTTTCTACTCACTCTGTGG
AAACCAATGTGAAAAAACTGAAGAAAATGAAAAAAATCTCGACACCTTGA
GCAGAGATTCTCAAATTACTTTTTCTCCTCCGAAAAAAATGAAATCTTTC
AACTTTAGAAAACTAGCAATACCATTAGAATCAGAAATTGATAAATTAGT
TAAATATTTCGAAAACAACTCCCAAAAATGTGTGGTAAAAGAACTTGTTG
AAGAAAAAGAGCAATTAATTGAATCGGGAATGTCTCGACTGGAATCTCGA
TTAAAGGCAATGTCTACGATTATAAAATCTATTGAGTCGAAATTTGAAGA
TTCTGAAAATCCAGGAAATCACAATTCTGCAGAAATGGGCAATTGTTATT
ATCCAACACTGGATATTAGTGAATTTGAAGTCCAAAATCCAACAACATTT
ATTGAAGAAGACATCATTAATACAAATAAAGAAATAGTGTCACTGATTCA
TGATCTGAGAACTGGCCAGCTGTCGGTCTCTGCTCCTTCGTCAAATGCAA
ACGTCAGGTCCAGTTTCTTGATTCCTAGAATAATTGTCGATGAAAATTGT
GACAACAATTTTTCTGATCCAAATTCTGACTTGGGTGGAAATAAATTGAA
AAATTGGGTCACTGAGTTGATCAACATTGATTCAGAAACTGTTCTGGAAG
TCCAAAATCTGCAGAAAAAACTCTGTGATTTTCAAGATCATGTTGTGGAA
TCATTTACCAAAATCGAATCATTCTTG

protein sequence of SMED30005926-orf-1

>SMED30005926-orf-1 ID=SMED30005926-orf-1|Name=SMED30005926-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=275bp
MFSLVMEYYTKPLFPLPFSIFAHAFDFFYSLCGNQCEKTEENEKNLDTLS
RDSQITFSPPKKMKSFNFRKLAIPLESEIDKLVKYFENNSQKCVVKELVE
EKEQLIESGMSRLESRLKAMSTIIKSIESKFEDSENPGNHNSAEMGNCYY
PTLDISEFEVQNPTTFIEEDIINTNKEIVSLIHDLRTGQLSVSAPSSNAN
VRSSFLIPRIIVDENCDNNFSDPNSDLGGNKLKNWVTELINIDSETVLEV
QNLQKKLCDFQDHVVESFTKIESFL

protein sequence of SMED30005926-orf-2

>SMED30005926-orf-2 ID=SMED30005926-orf-2|Name=SMED30005926-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=994bp
MNKTVSTTGDSFSQNELFAQAVHQARFRLTDGSKNSNVNFNANDEKNHLK
GFIKKKFHSIDCRFFVEKSKELSNKQTKCLCGELKSEHKKDKIPYNKVND
WSIHSCFETVPTESFGKIEFIGEDVTNTKLTEFVRLSHEDNLDDVMKLMF
DYWNIEIGTLCISVLGGTKNFKMKKKEKYIFYQGLIKAVKTTNALILTSG
LNLGITRFVGDAIQNGQCDLYDKAKGNNSLCCLGIAPWGFVKNKKILEHA
KGTIIKYKVSNEILLTEPVSLNKNHTHYLFVDEHERFDYSNSKASDFREA
LEKKLSQRTKNKEPIPVVLLLIEGEYDVFFEASKRIKENVPIVICVGTGR
ASDLLGEAFREMQKYPIKQLRPDGVPMLPEMYRNSLKKKLIDKNVSNPDK
VNEALNYIEEIIHKEYLITLFDVKEDHDLELAILYSLIKRMDFTSDSKLN
TLSSQLSLCLKWNRVDIAKDKIFSGVVSLSKENWALFLKESIINGKYEFV
ELFLQNGAVMNDFLTTTTLEKLYEDCPRSFNLKRTIFHFLGRNFSNGLGD
VKDLLTKIFGYYEDQCAMCDEEIIHPFQELFIWSVLMENHECANYFWEKT
EESLCLALVATKIYKCLMEMSPLDTSRIETLSNWKDYFENLAIKLLEECH
DADQETAAYIIEKENITWGGYTCLEIAYKAEDQKFISCMVCQNSLDFTWR
AGFNINLFQCILCIFLPFLIYRRSFDNSYVIHESKKKDDTSNKGYFTNSG
NWPLKLVQFYLAPQTKFCIHSLAFSVSVFYFSYVVLFGMKRMQFTIHEIL
FIIYLICMNIEKFAEMFQYKTNKVGDRIKYWWNFNNWNKVDILMVILSAM
AMILRFPLLLKNWNGDIVMIYRCSKTIYSLIVGYFYLRFLRLISVHKNLG
PKIVMISKMLYQLMFYIIIMLIILLAYGITMQGAYFPQRDFSLNTLPNIM
DYPYWAIFGEITLNQLICLGVMTKQQIIIFQMNALNSTILFRF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0005216	ion channel activity

Vocabulary: **biological process**
Term	Definition
GO:0006811	ion transport
GO:0034220	ion transmembrane transport
GO:0055085	transmembrane transport

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000096	ventral epidermis
PLANA:0000204	ovary
PLANA:0000208	testis

Vocabulary: **INTERPRO**
Term	Definition
IPR041491	TRPM_SLOG

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR041491	TRPM, SLOG domain	PFAM	PF18139	LSDAT_euk	coord: 132..364 e-value: 1.2E-55 score: 188.7
None	No IPR available	PANTHER	PTHR13800	TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6	coord: 50..967
None	No IPR available	TMHMM	TMhelix		coord: 767..789
None	No IPR available	TMHMM	TMhelix		coord: 910..932
None	No IPR available	TMHMM	TMhelix		coord: 699..721
None	No IPR available	TMHMM	TMhelix		coord: 868..890
None	No IPR available	TMHMM	TMhelix		coord: 952..971
None	No IPR available	TMHMM	TMhelix		coord: 793..810
None	No IPR available	TMHMM	TMhelix		coord: 831..853

Main menu

Transient receptor potential cation channel subfamily M member 6

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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