Transducin beta-like protein 3

Query:   66 THFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYH----KSKINILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESD-NIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCL--------AVLSLK-----GNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            T++ +  K   FY  GK     +   +    G  +N ++  S   LR + Q ++  E++T F  +PD+  ++ A + L+L        S   ++W + H AP+ TM  + +ST L TGG D  VR+W I +  G     T+H       ++++  HP    +++ SS  D  I  W  +    L V + H  +VT + F    + M +S RD+  IIW+ ++      +PV ES+E  V++ +   +P     +  +G  S  +  ++   +  ++ ++ AS               G +     L     ++    +D N+  Y ++ ++L+ + +G   +V D+  +G     ++V  ++P +++F               +L    CQ++HG H+  + ++ VF  G    S  KD  V IW++  + ++    +         V +VC  R  +   V  S +DC         A+LS       G  L +     + H   I+++ +  N  LLATGS+D+  KLW+      +  + GV  GH+R +  V+FS  +Q+L TAS D  IKLW ++  +CL+ F+   A V +  F +   Q++S  SDG + +W     +     D H+ ++         D    G    +S S + L++D TE    + +  +E+Q   +QEL+NLL E +++ AL LAI L++P      + AI  + E  A E + A  L  + D  +A           L  F V W TN+R C   + V+G++L   A  EL ++      + A   Y+++H++R +    +  F D+L
Sbjct:   13 TNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRSLEQEDQ--EDITAFDLSPDNEVLVTASRALLLAQWAWQEGSV-TRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYG-----THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPE---EP-----VSQLGVKSPGLYFLTAGDQGTLRVWEAAS--GQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF---------------ELQTSACQILHG-HTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQV--MCVAQGSGHTHSVGTVCCSRLKESFLVTGS-QDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALP----QCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTG----ASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPE--ACEKLEATMLRLRRDQKEA-----------LLRFCVTWNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAFLDFL 784          

Query:  333 KIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYH----KSKINILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESD-NIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            ++W + H AP+ TM  + +ST L TGG D  VR+W I +  G     T+H       ++++  HP    +++ SS  D  I  W  +    L V + H  +VT + F    + M +S RD+  IIW+ ++      +PV ES+E  V++ +   +P     +  +G  S  +  ++   +  ++ ++ AS               G +     L     ++    +D N+  Y ++ ++L+ + +G   +V D+  +G     ++V  ++P +++F        E +  +       CQ++HG H+  + ++ VF  G    S  KD  V IW++  + ++ LK   S +V      +V +    K +    +  D        G  L +     + H   I+++ +  N  LLATGS+D+  KLW+      +  + GV  GH+R +  V+FS  +Q+L TAS D  IKLW ++  +CL+ F+   A V +  F +   Q++S  SDG + +W     +     D H+ ++         D    G    +S S + L++D TE    + +  +E+Q   +QEL+NLL E +++ AL LAI L++P      + AI  + E  A E + A  L  + D  +A           L  F V W TN+R C   + V+G++L   A  EL ++      + A   Y+++H++R +    +  F D+L
Sbjct:   10 RLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYG-----THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPE---EP-----VSQLGVKSPGLYFLTAGDQGTLRVWEAAS--GQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF--------ELQTSA-------CQILHG-HTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMLK--ESFLVTGSQDCTVKLWPLPKALLSKNTAPD-------NGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALP----QCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTG----ASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPE--ACEKLEATMLRLRRDQKEA-----------LLRFCVTWNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAFLDFL 673          

Query:  372 MCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYH----KSKINILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESD-NIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCL--------AVLSL-----KGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHK---RCISSVKFS---DTEQLLLTA----SLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQI 1904
            M  + +ST L TGG D  VR+W I +  G     T+H       ++++  HP    +++ SS  D  I  W  +    L V + H  +VT + F    + M +S RD+  IIW+ ++      +PV ES+E  V++      PE    +  +G  S  +  ++   +  ++ ++ AS               G +     L     ++    +D N+  Y ++ ++L+ + +G   +V D+  +G     ++V  ++P +++F        E +  +       CQ++H GH+  + ++ VF  G    S  KD  V IW++  + +  +  +         V +VC  R  +   V  S +DC         A+LS       G  L +     + H   I+++ +  N  LLATGS+D+  KLW+      +  + GV  GH+      SS+ ++      QL+  +    S    +      ++ CL          +  F +   Q++S  SDG + +W     +     D H+ ++
Sbjct:    1 MAFDPTSTLLATGGCDGAVRVWDIVRHYG-----THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLL------PEEP--VSQLGVKSPGLYFLTAGDQGTLRVWEAAS--GQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF--------ELQTSA-------CQILH-GHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQ--VMCVAQGSGHTHSVGTVCCSRLKESFLVTGS-QDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWAL----PQCQLLGVFSGHRVASGASSSLPWTRCWPRPQLMAPSSSGHSRTSAVSRHLRGTMLCL----------KVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKV 493          

Query: 1008 FYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSV--CVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAV-HRAMFYNNEKQIISCHSDGT 1838
            + ++  QL + L G+   VK                 +P   LFA  S + T    D  +     C  V  GH + + +VS   D  Q+ SGG D +V +W V+    LRL +     +++   S    C+        VH  I D   V     +Q          HS  IS +  +  S LLA+GS DK + +W   T S  L+I+  LKGH   + S+ FS  E  L +A   +++K+W   +  CL+  K    V H   F  + K ++S  +D T
Sbjct:   48 WETRSGQLLWRLGGHTGPVK-------------FCRFSPDGHLFASASCDCTVRLWDVARAK---CLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVH--IWDLRMVTPAVSHQALEG------HSANISCLCYSA-SGLLASGSWDKTIHIWKPTTSS--LLIQ--LKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQT 298          

Query: 1218 GGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKL-RLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFS--KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIV 1847
            G H  ++ S +   DG  +++G +DG V  W+      L RL   T  V         C       ++   S  DC   L      + R  C    K H   + T+  + +S  LA+G  DK V LW    +S +++   +L GH+  I S  FS T   L T S D  + +W +  +T       P   H+A+  ++      C+S   ++ 
Sbjct:   18 GQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPV-------KFCRFSPDGHLFASASC-DCTVRLW----DVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLW--DVQSGQMLR--LLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVT-------PAVSHQALEGHSANISCLCYSASGLLA 207          

Query: 1008 FYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSV--CVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT--AVHRAMFYNNEKQIISCHSDGT 1838
            + ++  QL + L G+   VK                 +P   LFA  S + T    D  +     C  V  GH + + +VS   D  Q+ SGG D +V +W V+    LRL +     +++   S    C+        VH  I D   V     +Q          HS  IS +  +  S LLA+GS DK + +W   T S  L+I+  LKGH   + S+ FS  E  L +A   +++K+W   +  CL+  K       H   F  + K ++S  +D T
Sbjct:   48 WETRSGQLLWRLGGHTGPVK-------------FCRFSPDGHLFASASCDCTVRLWDVARAK---CLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVH--IWDLRMVTPAVSHQALEG------HSANISCLCYSA-SGLLASGSWDKTIHIWKPTTSS--LLIQ--LKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKQGVLDVAHTCAFTPDGKILVSGAADQT 299          

Query: 1218 GGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKL-RLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFS--KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIV 1847
            G H  ++ S +   DG  +++G +DG V  W+      L RL   T  V         C       ++   S  DC   L      + R  C    K H   + T+  + +S  LA+G  DK V LW    +S +++   +L GH+  I S  FS T   L T S D  + +W +  +T       P   H+A+  ++      C+S   ++ 
Sbjct:   18 GQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPV-------KFCRFSPDGHLFASASC-DCTVRLW----DVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLW--DVQSGQMLR--LLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVT-------PAVSHQALEGHSANISCLCYSASGLLA 207          

Query:  333 KIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYH------KSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEF--KKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQV----EDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKG-----------------NQLTRKSCFSK--PHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT-AVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            + W + H API  M  N+    L TG AD  V++W++ + +     CT+        S I   ++  L+   +   +  ++I+    +  K +  +  H   +T +     S  +   SRD+T+ I   E    L ++P+ ES+E   I                  G +G + TV   +  +++EF  + A L      A  N D      + +    I +     E + I    + +++  ++ G   ++    ++GK++  + V  +   +RL+  K+ +               CQL+ G     ++ VS   D   + S  KD  +  W++    E+ +   L  + +     + V+++ +   G+  ++     DC   L   G                  QL + +C S    H   ++ ++++ + +L+ATG  DK VKLW   T   +L I G L GH+R +  VKF+     L + S D  IK+W +   +CLQ     + AV R +F  N+ Q+IS  S G + +W   T       D H  +I   +     + N   F  A +   + +++D TE+  +     R +  +++Q L NLL + ++  AL  A+ L KP   +  +NA+             A E P+  ++G A++ LD  ++  L  F VKW TN+RT  + + V+  ++  +   EL S P    +I +F  Y+ +H  R +         D++
Sbjct:  102 RTWKTIHTAPILVMEFNEEGHLLATGSADHIVKVWNLTEQQ-----CTHTLKGPSVVSAILFGKHEKLVVGYIEGQLNLYNIMRGAPK--KLVNTWKSHNSHITALLQVPDSRVVVALSRDQTMSIHETETQETLRVLPLYESIEGGAI------------------GHNGNLFTVG--EEGVVKEFVIETAKLVRKKRIASSNLDHLAYDVVSNRFLAISA-----EQNLIILDFENLKIARQIVGFHDEIYSCCLLGKDESHMAVASNTSEIRLYNTKTLD---------------CQLIRGHTESVLSVVSPTWDTSLLASCSKDNSIIFWRLVTSPENDSCSTLVPVAAATGHANTVTALAISNTGRAPFLASVSTDCTIKLWGLGVSTKLKEVKIDAEKDFVEQLPKLTCSSTMVAHGKDVNCVDISESDALIATGGMDKLVKLWQVDTHKMQLGIAGTLSGHRRGVGDVKFAKNSHKLASCSGDMTIKIWNISEKSCLQTISGHSCAVFRVIFARNDSQLISADSAGIIKIWTIKTADCECSIDAHTDKIWSLS----KNHNESEFVTAGTDGRIVVWKDVTEEKQKAEDNKRREAIEQDQTLTNLLSQKRYSEALVFALTLAKPFCAFKVINALM------------AEETPE--ELGSAIRRLDTRQIEILLQFTVKWNTNSRTSSVAQRVLYEIVHIVDPEELVSMPGAYGYIESFLPYTQRHMDRLDRAKQDVSLFDFV 785          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIV---SSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLW------CVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCF 1913
            GH+K I+S      G  + +   D  V IW + D       L    +  NDI     S CV        V  S +  L +  +  +++T+     K H+N +     N  SSL+ +GS D++V++W  KT    + IK  L  H   +S+V F+    L+ + S D ++++W      C+++L  + D   P A  +  F  N K I++ + D T+ +W+   GK   ++  H+    C 
Sbjct:   85 GHTKSISSAKFSPCGKYLGTSSADKTVKIWNM-DHMICERTLTGHKLGVNDIAWSSDSRCV--------VSASDDKTLKIFEIVTSRMTKTL---KGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTG---MCIK-TLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTL--VDDENPPVAFVK--FSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCI 304          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIV---SSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLW------CVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCF 1913
            GH+K I+S      G  + +   D  V IW + D       L    +  NDI     S CV        V  S +  L +  +  +++T+     K H+N +     N  SSL+ +GS D++V++W  KT    + IK  L  H   +S+V F+    L+ + S D ++++W      C+++L  + D   P A  +  F  N K I++ + D T+ +W+   GK   ++  H+    C 
Sbjct:   85 GHTKSISSAKFSPCGKYLGTSSADKTVKIWNM-DHMICERTLTGHKLGVNDIAWSSDSRCV--------VSASDDKTLKIFEIVTSRMTKTL---KGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTG---MCIK-TLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTL--VDDENPPVAFVK--FSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCI 304          

Query: 1503 HSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNE--KQIISCHSDGTMIVWNRDTGKDSSKF 1883
            H   I T + + + S LA+   D+ + LW+   + +      VLKGHK  I  VKF+     L++A  DK +++W +E+ +C+++FKS T +  ++  N    + I S   DGT++V +  + + + KF
Sbjct:   35 HGGEIYTSQFSSDGSFLASAGYDQQIFLWNVFGECENF---AVLKGHKGAIMEVKFNADSSHLVSAGTDKTVRVWDMETGSCIRNFKSHTDIVNSVDVNRRGPQMICSASDDGTVMVHDMRSKEAAKKF 160          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISC------------HSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTL 1919
            GH   I  V   +D   +VS G D  V +W +E  + +R     +     DIV+SV V+R+G  +    S +  + V  ++  +  +K       + +      N  +  +  G  D  +K+W          ++ VL GH+  I+S+  S     LL+ S+D  +  W +      Q      A ++   +N EK ++ C             +D  + VWN  +     K   H G ++C  L
Sbjct:   77 GHKGAIMEVKFNADSSHLVSAGTDKTVRVWDMETGSCIR-----NFKSHTDIVNSVDVNRRGPQMICSASDDGTVMVHDMRSKEAAKKFICKYQQTAVT----FNDAADNVICGGIDNQIKVWDMLRND----VRYVLSGHRDTITSLSVSHNGNFLLSNSMDCSLMSWDIRPFVPAQRL---VARYQGASHNFEKNLLKCGWSPRDNYITAGSADRFVYVWNAKSRACVYKLPGHLGSVNCTAL 305          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLK-GNQLTRKSCFSKPHSNI-ISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQII 1817
            GH+K I +V +  D +  +S   D  + +W   DS+   +     I V    V+ + ++  G +I +  S +   A   ++ G  L + S   +P S I + ++E + +  +  TG+ D  VK+W  K ++    +     GH   + S+ FS+    L T S D  +KLW +  L  L+            F N EKQ I
Sbjct:  249 GHNKKINAVVLHPDNITAISASADSHIRVWSATDSSSKAI-----IDVHQAPVTDISLNASGDYI-LSASDDSYWAFSDIRSGKSLCKVSV--EPGSQIAVHSIEFHPDGLIFGTGAADAVVKIWDLKNQT----VAAAFPGHTAAVRSIAFSENGYYLATGSEDGEVKLWDLRKLKNLK-----------TFANEEKQPI 426          

Query:   87 KFHSFYNAGKNICVTSDGF-IISDDGESINYIDKNSLRKINQF--------NKTSEEM----------TCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRL-TTGGADSKVRIWHIGQGE---------GKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELS---NQMATSSRDETVIIWNCEN---FNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQ--TIDSLIFVRESDNIEFYS-KQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIV-VENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKS-CFSKPHSNIISTMEMNI-----NSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVH-ALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEY---STFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            ++ +FY AG +I  + +G  +   +G ++N +D  + + +N +        NK   E+          TCF  + +          L L  +D   L K   +W + HK P+  +  +     + T+GGAD+ +R+W               G ++   +H    N+LR        + +   D  + AW+ ET   +    GH   VTG+ F   +   N++ T SRD+ +I+W  +      +L ++P+ + LE  V+ +D       +  L++V   SG ++ V P K   I++    S F+                I  +L    +  L  V    NI  Y  + ++    L G   ++ D+  +G++   + V  ++ + +L+      +TE++ +        C+L+  GHS  + S++   + L  +S GKD  V +W+++      L+ +T         +  V +   G   +   S +  + V  L  ++  R S  F+  ++ +    E+N      N+ L+AT S+DK  K+W  ++ +    ++GVL+GH R + SV+FS  +Q++LT+S D  +++W + + +C++ F     + RA F ++ K IIS  SDG + +WN  T       D H+ ++  + L      N R F    + S +  + D T+    ++   R+   ++EQ L++LL   K +H A  LA+ L+KP  +++ +N      ++P     G  +L D+ ++ + V          L      W TN+R    G  ++  ++G   DA L     +      +     Y  +H++R  E      F +++
Sbjct:   15 RYTNFY-AGGDIAWSPNGHHLYCLNGSAVNQVDVQTSQILNSYGLSSPSADNKRPAELDNIDVEEDTITCFGLSQEHLVTAHRSGLLRLWQLDTGKLVK---LWKAQHKGPVIRVEFSPCGRLICTSGGADATLRLWDYSNNSCLGALKDFPGPAWLLVFHP---NVLRKE------IYAGGSDNTVYAWNYETKTLVHKMRGHLSQVTGLSFKSNASDCNEIVTVSRDKVMIVWQLQEQLESKQLKVLPLYDELEG-VVYAD-------EGQLIIVASGSGKLQQVDP-KSWKIRDILSQSDFQ----------------ISRLLHCSELKQLALVTTEQNILVYDVETLEPIKHLVGYNDEILDMCFMGEHDRYLAVATNSKHFKLY------DTEHDMN--------CKLI-VGHSDTVMSLAASQNLL--ISVGKDCSVRLWRLQHDKDCSLEALTQQANCHTSTIGCVAMTHNGATGFASVSQDGSMKVWQLVRSKEDRNSYSFNLRYAALSHDKEVNCVAYAPNNKLIATASQDKTAKVWLAESNT----LQGVLRGHTRGVWSVRFSPVDQIVLTSSSDCTLRIWSISNFSCIKRFDQECTILRAEFLDHGKFIISAASDGLLKLWNIKTNTCLQSLDEHNDRV--WALAVSARSN-RFFYTGGADSKLIRFGDVTQVTRNEALDKRQAALEQEQTLHSLLHAQKQLHKAFVLALNLDKPKASFDIINHFVRKRDEP-----GLRQLVDQLNVDQRV---------ALLQHVKAWTTNSRHSQAGNMILKYLIG---DALLDPKARFYYNGNMVEVLTPYVQRHFKRVTELNKDLAFLEFI 783          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDK-NVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSD--TEQLLLTASLDKVIKLW-CVES 1739
            GHS ++T ++  SDG  I +GG+D KV +W  + S         +       V+ +   R  KF+ V  S++  +    +  N+      F+ P+    S + ++ +  L+  G +D  ++ LWS KT      +  ++ GH+  + S+ FS   T   L++ S DK +K+W C+ES
Sbjct:  391 GHSSEMTCIAYSSDGQFIATGGEDSKVKLWNTQSSF-----CFVTFSEHTSGVTGIQFSRNKKFL-VSSSLDGTVRAFDV--NRYRNFRTFTSPNPAQFSCVAVDYSGELVVAGGQDVFDIFLWSVKTGK----LLEIISGHEGPVVSIAFSPVATSSTLVSGSWDKTVKIWNCLES 555          

Query:  222 SEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHEL--SNQMATSSRDETVIIWNC 701
            S EMTC   + D   +    ++  +K+ +    S    +  S H + +  +  +++   L +   D  VR + + +        + + ++ + +       +VV+     FDI  W  +TGK L + SGH+  V  I F  +  S+ + + S D+TV IWNC
Sbjct:  393 SSEMTCIAYSSDGQFIATGGEDSKVKLWNTQ--SSFCFVTFSEHTSGVTGIQFSRNKKFLVSSSLDGTVRAFDVNRYRNFRTFTSPNPAQFSCVAVDYSGELVVAGGQDVFDIFLWSVKTGKLLEIISGHEGPVVSIAFSPVATSSTLVSGSWDKTVKIWNC 552          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDK-NVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSD--TEQLLLTASLDKVIKLW-CVES 1739
            GHS ++T ++  SDG  I +GG+D KV +W  + S         +       V+ +   R  KF+ V  S++  +    +  N+      F+ P+    S + ++ +  L+  G +D  ++ LWS KT      +  ++ GH+  + S+ FS   T   L++ S DK +K+W C+ES
Sbjct:  391 GHSSEMTCIAYSSDGQFIATGGEDSKVKLWNTQSSF-----CFVTFSEHTSGVTGIQFSRNKKFL-VSSSLDGTVRAFDV--NRYRNFRTFTSPNPAQFSCVAVDYSGELVVAGGQDVFDIFLWSVKTGK----LLEIISGHEGPVVSIAFSPVATSSTLVSGSWDKTVKIWNCLES 555          

Query:  222 SEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHEL--SNQMATSSRDETVIIWNC 701
            S EMTC   + D   +    ++  +K+ +    S    +  S H + +  +  +++   L +   D  VR + + +        + + ++ + +       +VV+     FDI  W  +TGK L + SGH+  V  I F  +  S+ + + S D+TV IWNC
Sbjct:  393 SSEMTCIAYSSDGQFIATGGEDSKVKLWNTQ--SSFCFVTFSEHTSGVTGIQFSRNKKFLVSSSLDGTVRAFDVNRYRNFRTFTSPNPAQFSCVAVDYSGELVVAGGQDVFDIFLWSVKTGKLLEIISGHEGPVVSIAFSPVATSSTLVSGSWDKTVKIWNC 552          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFS-KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQ---DFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDC-FTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEK 2018
            GH+K +++V    +G  + S   D  + IW   D      K   +I      +S V      + + V  S +  L V  L     T KS  + K HSN +     N  S+L+ +GS D++V++W  +T      +K  L  H   +S+V F+    L++++S D + ++W   S  CL+   D  +P  V    F  N K I++   D T+ +W+   GK    +  H  +  C F   + T G  +   + S  +M+ ++  ++++ ++K
Sbjct:   70 GHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDG-----KFEKTISGHKLGISDVAWSSDSRLL-VSGSDDKTLKVWELS----TGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGK---CLK-TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG--KWIVSGSEDNMVYIWNLQSKEVVQK 323          

Query:  345 SCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGE------GKS---FCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWN 698
            S HK  I  +  +  S  L +G  D  +++W +  G+      G S   FCC ++          P  N++VS S  D  +  WD  TGK L     H D V+ + F+   + + +SS D    IW+
Sbjct:  111 SGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFN----------PQSNLIVSGS-FDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 226          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFS-KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQ---DFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDC-FTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEK 2018
            GH+K +++V    +G  + S   D  + IW   D      K   +I      +S V      + + V  S +  L V  L     T KS  + K HSN +     N  S+L+ +GS D++V++W  +T      +K  L  H   +S+V F+    L++++S D + ++W   S  CL+   D  +P  V    F  N K I++   D T+ +W+   GK    +  H  +  C F   + T G  +   + S  +M+ ++  ++++ ++K
Sbjct:   70 GHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDG-----KFEKTISGHKLGISDVAWSSDSRLL-VSGSDDKTLKVWELS----TGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGK---CLK-TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG--KWIVSGSEDNMVYIWNLQSKEVVQK 323          

Query:  345 SCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGE------GKS---FCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWN 698
            S HK  I  +  +  S  L +G  D  +++W +  G+      G S   FCC ++          P  N++VS S  D  +  WD  TGK L     H D V+ + F+   + + +SS D    IW+
Sbjct:  111 SGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFN----------PQSNLIVSGS-FDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 226          

Query:   66 THFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNSLRKINQFNKTSEE-MTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPE----ADAYLVMVGGASGIIKT--VSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSL------KGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQI 1904
            +++ +  +   FY  GK      +  I    G  IN +  ++ + I+   +  +E +T F  +PDD  ++ A + L+L+  D     +  + W + H  P+ +M  + +ST L TGG D  +++W +     K +C    K     ++++  HP +  + + SS  D  I  WD  + + + V   H   VT + F    + + +S RD+   +W+ +       IPV E++E  V++S   +  E    +DA  ++  G+ G+++    S S+ V  Q    AS   + E  D   ++        +L     LI V    NI  Y +  + ++ +  G   DV D+  VGK+   I V  ++  +++F               +LS   CQ++HG H+  I S+ VF  G    +  KD  V +W+++ S+  R+  +      ++ V S+   R  +   V  S +  + V  L      +G  + +     + H   ++++ ++ N  LLA+GS+D+  KLW+      +L + GV +GH+R + SV+FS  +Q+L +AS D  +++W ++  +CL+ F+   A V + +F +   Q++S  SDG + +W   T +     D H  ++
Sbjct:   10 SNYAVSSRIEPFYKGGKVQVSGDEQHIFCTYGPKINILQISTGKIIHSIEQEDQEDITAFALSPDDEMLVSASRALLLRQWDWKQ-QQCRRSWRAVHSVPVASMSFDCTSTLLATGGCDGTIKLWDVI----KQYCTHNLKGSSGVVHLVEFHPDISRLQLFSSSSDCAIRIWDLRSSRCVCVLESHYSPVTALAFSPDGHTLVSSGRDKICSVWDLQEQKVKRTIPVYEAVEGVVLLSGSADYSEMGVKSDALHLVTAGSKGVLRVWDSSSSRCVFTQTLPDAS--SHTEDEDAEDEERLGLLQLLLLPRTGRLITVTAEHNILLYQTPTLAVQQQFVGYNDDVLDVKFVGKDDTHIAVATNSSQLKVF---------------ELSTNSCQILHG-HTDTILSIDVFRKGSMFATCAKDKSVRVWRMDVSSG-RVHCVAQGTGHSNAVGSIACSRMKQQFVVSGSQDCTVKVWDLPETTGAEGVMMMKARSTERAHEKDVNSVCVSPNDKLLASGSQDRTAKLWALS----DLRLLGVCRGHRRGVWSVQFSPVDQILGSASADGSVRIWSIQDFSCLKTFEGHDASVLKIIFVSRGTQLVSSGSDGLVKLWTIKTNECVRTLDAHQDKV 613          

Query: 1224 HSKDITSVSVF-SDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT-AVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDI---HDGQIDCF-TLITDTDGNC 1943
            HS +++S+ +  S G  + +GG+D +V+IW V      +   I S+      V  +  +   + + V  S+   L +  L+  ++ R       H   IS+++ +     LA+GS D N+KLW  + K    + +   KGH + +  + FS   + L +AS D  +KLW + +   + +F S T AV+   F+ NE  + S  +D T+ +W      D  KF++    +G+     +++ + DG+C
Sbjct:   19 HSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVS-----KPNCIMSLTGHTSAVGCIQFNSSEERV-VAGSLSGSLRLWDLEAAKILRTL---MGHKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKG--CVFR--YKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLW------DLEKFNMIGSSEGETGVVRSVLFNPDGSC 245          

Query:  351 HKAPIFTMCLNKSSTRL-TTGGADSKVRIWHIGQGEGKSFC---CTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWN 698
            H + + ++ L KSS RL  TGG D +V IW +     K  C    T H S +  ++ +     VV+ S L   +  WD E  K L    GH+ S++ +DFH +   +A+ S D  + +W+
Sbjct:   19 HSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVS----KPNCIMSLTGHTSAVGCIQFNSSEERVVAGS-LSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMGEYLASGSVDSNIKLWD 133          

Query: 1203 CQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCF--SKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYN 1799
            C +   GH+  +  +   S   ++V+G   G + +W +E +     K++ +++     +SS+     G+++    S++  + +  ++     RK C    K H+  +  +  + +   LA+ S D  VKLW     + ++I +     H   ++ V+F   E LL + S D+ +KLW +E    +   +  T V R++ +N
Sbjct:   55 CIMSLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAA-----KILRTLMGHKASISSLDFHPMGEYL-ASGSVDSNIKLWDVR-----RKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDL--IAGKMITE--FTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMIGSSEGETGVVRSVLFN 240          

Query:  351 HKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMN 779
            HKA I ++  +     L +G  DS +++W + + +G  F    H   +  L   P    + S+S  D  +  WD   GK +  F+ H  +V  + FH     +A+ S D TV +W+ E FN   +I   E  ET V+ S   N
Sbjct:  104 HKASISSLDFHPMGEYLASGSVDSNIKLWDVRR-KGCVFRYKGHTQAVRCLAFSPDGKWLASASD-DSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFN---MIGSSEG-ETGVVRSVLFN 240          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDK-NVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLW-CVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKF-DIHDGQI 1904
            GH  ++ S++   DG  + +GG DGKV +W         L  +T     +  V+ V     G F+ V  S++  +    L   +  R    + P     S++ ++ +  L+  GS+D   + LWS +T      +  VL GH+  +S++ FS  + +L + S DK ++LW  ++S    +  +  +      ++ N  ++     DG +  WN  TG+ +      HD Q+
Sbjct:  383 GHFNNMNSLAYSPDGQYLATGGDDGKVKVWNTNSG----LCFVT-FTEHSSGVTEVAFTSSG-FVVVSASLDGTVRAFDLHRYRNFR--TMTSPRPAQFSSLAVDGSGELVCAGSQDSFEIFLWSMQTGR----LLEVLSGHEGPVSNLCFSPVQSVLASVSWDKTVRLWDMLDSWQTKETLQLTSDGLAVTYHPNGMELAVASLDGEITFWNPQTGRQTGSITGRHDLQM 601          

Query: 1221 GHSKDITSVSVF-SDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT-AVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDI---HDGQIDCF-TLITDTDGNC 1943
             HS +++S+ +  S G  + +GG+D +V+IW V      +   I S+      V  +  +   + + V  S+   L +  L+  ++ R       H   IS+++ +     LA+GS D N+KLW  + K    + +   KGH + +  + FS   + L +AS D  +KLW + +   + +F S T AV+   F+ NE  + S  +D T+ +W      D  KF++    +G+     +++ + DG+C
Sbjct:   18 AHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVS-----KPNCIMSLTGHTSAVGCIQFNSSEERV-VAGSLSGSLRLWDLEAAKILRTLMG---HKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKG--CVFR--YKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLW------DLEKFNMIGSSEGETGVVRSVLFNPDGSC 245          

Query: 1203 CQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCF--SKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVL----KGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIV--WNRD 1859
            C +   GH+  +  +   S   ++V+G   G + +W +E +     K++ +++     +SS+     G+++    S++  + +  ++     RK C    K H+  +  +  + +   LA+ S D  VKLW         +I G +      H   ++ V+F   E LL + S D+ +KLW +E    +   +  T V R++ +N +   +   S+ T+ V  W  D
Sbjct:   55 CIMSLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAA-----KILRTLMGHKASISSLDFHPMGEYL-ASGSVDSNIKLWDVR-----RKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKLWD--------LIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMIGSSEGETGVVRSVLFNPDGSCLYSGSENTLRVYGWEPD 262          

Query:  348 CHKAPIFTMCLNKSSTRL-TTGGADSKVRIWHIGQGEGKSFC---CTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWN 698
             H + + ++ L KSS RL  TGG D +V IW +     K  C    T H S +  ++ +     VV+ S L   +  WD E  K L    GH+ S++ +DFH +   +A+ S D  + +W+
Sbjct:   18 AHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVS----KPNCIMSLTGHTSAVGCIQFNSSEERVVAGS-LSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMGEYLASGSVDSNIKLWD 133          

Query:  351 HKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKL 719
            HKA I ++  +     L +G  DS +++W + + +G  F    H   +  L   P    + S+S  D  +  WD   GK +  F+ H  +V  + FH     +A+ S D TV +W+ E FN +
Sbjct:  104 HKASISSLDFHPMGEYLASGSVDSNIKLWDVRR-KGCVFRYKGHTQAVRCLAFSPDGKWLASASD-DSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMI 224          

Query: 1221 GHSKDITSVSVF-SDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT-AVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDI---HDGQIDCF-TLITDTDGNC 1943
             HS +++S+ +  S G  + +GG+D +V+IW V      +   I S+      V  +  +   + + V  S+   L +  L+  ++ R       H   IS+++ +     LA+GS D N+KLW  + K    + +   KGH + +  + FS   + L +AS D  +KLW + +   + +F S T AV+   F+ NE  + S  +D T+ +W      D  KF++    +G+     +++ + DG+C
Sbjct:   18 AHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVS-----KPNCIMSLTGHTSAVGCIQFNSSEERV-VAGSLSGSLRLWDLEAAKILRTLMG---HKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKG--CVFR--YKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLW------DLEKFNMIGSSEGETGVVRSVLFNPDGSC 245          

Query: 1203 CQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCF--SKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVL----KGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIV--WNRD 1859
            C +   GH+  +  +   S   ++V+G   G + +W +E +     K++ +++     +SS+     G+++    S++  + +  ++     RK C    K H+  +  +  + +   LA+ S D  VKLW         +I G +      H   ++ V+F   E LL + S D+ +KLW +E    +   +  T V R++ +N +   +   S+ T+ V  W  D
Sbjct:   55 CIMSLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAA-----KILRTLMGHKASISSLDFHPMGEYL-ASGSVDSNIKLWDVR-----RKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKLWD--------LIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMIGSSEGETGVVRSVLFNPDGSCLYSGSENTLRVYGWEPD 262          

Query:  348 CHKAPIFTMCLNKSSTRL-TTGGADSKVRIWHIGQGEGKSFC---CTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWN 698
             H + + ++ L KSS RL  TGG D +V IW +     K  C    T H S +  ++ +     VV+ S L   +  WD E  K L    GH+ S++ +DFH +   +A+ S D  + +W+
Sbjct:   18 AHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVS----KPNCIMSLTGHTSAVGCIQFNSSEERVVAGS-LSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMGEYLASGSVDSNIKLWD 133          

Query:  351 HKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFN 713
            HKA I ++  +     L +G  DS +++W + + +G  F    H   +  L   P    + S+S  D  +  WD   GK +  F+ H  +V  + FH     +A+ S D TV +W+ E FN
Sbjct:  104 HKASISSLDFHPMGEYLASGSVDSNIKLWDVRR-KGCVFRYKGHTQAVRCLAFSPDGKWLASASD-DSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFN 222          

Query:   72 FQLFDKFHSFYNAGKNICVTSDG-FIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSD----FMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQ-MQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVH--------YSIEDCLAVLSLKGNQ---LTRKSCFS-KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNL--EKSKLDR 2033
            + +  K  +FY  GK   + +DG +I+   G  +N +D  +      I Q ++  E++T F  +PDD  ++   + L+LK  D        + W + H AP+ TM  + +ST L TGG DS ++IW +     K +C    K     +++++ HP +  + + SS +D+ I  WD +T K L V   H  +VT + F    N M +S RD+   +W+ E  +    +PV ES+E  V+  D       + ++ + L +  G+ GI++    +  V +       + E   T +   + S    +  ++     +  V    NI  Y  Q +QL+ + +G   +V D+  +G +   I+V  ++P +++F      + E  N         CQ+++ GH++ + ++ VF  GL   S  KD  + +W+++ +      +       N + +  C   K  F+           + + + LA    KGN     T  +C + K H   I+++ ++ N  L+A+GS+DK  KLWS    + +L + GV +GHKR I  V+FS+ +Q+L + S D  +KLW ++  +CL+ F+   A V + +F +   Q+++  SDG + +W   T +     D H+ ++       + D         S+ S + L++D TE  L  E++K D 
Sbjct:   16 YAVTRKIEAFYKGGKVQVIINDGTYILCTCGNKLNILDIATGAVTYTIEQDDQ--EDITSFALSPDDEILVTGSRALLLKQWDWKQ-GTCSRTWKAIHTAPVATMTFDPTSTLLATGGCDSTIKIWDVI----KQYCTHNLKGSSGVVHLVQFHPDMSRLQLFSSSMDYKIRLWDLKTSKCLCVMETHFSAVTSLCFSPDGNTMISSGRDKICTVWDLETKSPKRTVPVYESVEAVVLFPDSSDIICQENDSQSLLFLTAGSKGILRVWDAATAVCVYGQTLPHIAEGNSTEEEANEHSLTHCL--LIPGQHQVATVTAEHNILMYDLQNLQLKKQFAGYNDEVLDVKFLGPSDSHIVVATNSPQLKVF------DLETSN---------CQILY-GHTETVLALDVFKKGLLFASCAKDRTIRVWRMKKATGKVTCVAQGSGHTNGVGTISCSRMKEAFLVSGSQDYTIKLWKLPESLANKQSKGNSGDLETLLACATEKAHDKDINSVTVSPNDKLIASGSQDKTAKLWS----ATDLSLLGVFRGHKRGIWCVQFSNVDQVLASTSADGTLKLWGLQDFSCLKTFEGHDASVLKVVFVSRGAQLLTSGSDGLLKLWTIKTNECVKTLDTHEDKVWGLHCNREDD----ALVTGSADSAIILWKDVTETELAEEQAKEDE 664          

Query:   87 KFHSFYNAGKNICVTSDG-FIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSD----FMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQ-MQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVH--------YSIEDCLAVLSLKGNQ---LTRKSCFS-KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNL--EKSKLDR 2033
            K  +FY  GK + + SDG +I+   G  +N +D  +      I Q ++  E++T F  +PDD  ++   + L+LK  D        + W + H AP+ TM  + +ST L TGG DS ++IW +     K +C    K     +++++ HP +  + + SS +D+ I  WD +T K L V   H  +VT + F    N M +S RD+   +W+ E  +    +PV ES+E  V+  D       + ++ + L +  G+ GI++    +  V +       + E   T +   + S    +  ++     +  V    NI  Y  Q +QL+ + +G   +V D+  +G +   I+V  ++P +++F      + E  N         CQ+++ GH++ + ++ VF  GL   S  KD  + +W+++ +      +       N + +  C   K  F+           + + + LA    KGN     T  +C + K H   I+++ ++ N  L+A+GS+DK  KLWS    + +L + GV +GHKR I  V+FS+ +Q+L + S D  +KLW ++  +CL+ F+   A V + +F +   Q+++  SDG + +W   T +     D H+ ++       + D    G    S+ S + L++D TE  L  E++K D 
Sbjct:   19 KIEAFYKGGK-VQINSDGTYILCTCGNKLNILDIATGAVTYTIEQDDQ--EDITSFALSPDDEILVTGSRALLLKQWDWKQ-GTCSRTWKAIHTAPVATMTFDPTSTLLATGGCDSTIKIWDVI----KQYCTHNLKGSSGVVHLVQFHPDMSRLQLFSSSMDYKIRLWDLKTSKCLCVMETHFSAVTSLCFSPDGNTMISSGRDKICTVWDLETKSPKRTVPVYESVEAVVLFPDSSDIICQENDSQSLLFLTAGSKGILRVWDAATAVCVYGQTLPHIAEGNSTEEEANEHSLTHCL--LIPGQHQVATVTAEHNILMYDLQNLQLKKQFAGYNDEVLDVKFLGPSDSHIVVATNSPQLKVF------DLETSN---------CQILY-GHTETVLALDVFKKGLLFASCAKDRTIRVWRMKKATGKVTCVAQGSGHTNGVGTISCSRMKEAFLVSGSQDYTIKLWKLPESLANKQSKGNSGDLETLLACATEKAHDKDINSVTVSPNDKLIASGSQDKTAKLWS----ATDLSLLGVFRGHKRGIWCVQFSNVDQVLASTSADGTLKLWGLQDFSCLKTFEGHDASVLKVVFVSRGAQLLTSGSDGLLKLWTIKTNECVKTLDTHEDKVWGLHCNREDDALVTG----SADSAIILWKDVTETELAEEQAKEDE 661          

Query:   72 FQLFDKFHSFYNAGKNICVTSDG-FIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSD----FMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQ-MQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVH--------YSIEDCLAVLSLKGNQ---LTRKSCFS-KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNL--EKSKLDR 2033
            + +  K  +FY  GK   + +DG +I+   G  +N +D  +      I Q ++  E++T F  +PDD  ++   + L+LK  D        + W + H AP+ TM  + +ST L TGG DS ++IW +     K +C    K     +++++ HP +  + + SS +D+ I  WD +T K L V   H  +VT + F    N M +S RD+   +W+ E  +    +PV ES+E  V+  D       + ++ + L +  G+ GI++    +  V +       + E   T +   + S    +  ++     +  V    NI  Y  Q +QL+ + +G   +V D+  +G +   I+V  ++P +++F      + E  N         CQ+++ GH++ + ++ VF  GL   S  KD  + +W+++ +      +       N + +  C   K  F+           + + + LA    KGN     T  +C + K H   I+++ ++ N  L+A+GS+DK  KLWS    + +L + GV +GHKR I  V+FS+ +Q+L + S D  +KLW ++  +CL+ F+   A V + +F +   Q+++  SDG + +W   T +     D H+ ++       + D    G    S+ S + L++D TE  L  E++K D 
Sbjct:   12 YAVTRKIEAFYKGGKVQVIINDGTYILCTCGNKLNILDIATGAVTYTIEQDDQ--EDITSFALSPDDEILVTGSRALLLKQWDWKQ-GTCSRTWKAIHTAPVATMTFDPTSTLLATGGCDSTIKIWDVI----KQYCTHNLKGSSGVVHLVQFHPDMSRLQLFSSSMDYKIRLWDLKTSKCLCVMETHFSAVTSLCFSPDGNTMISSGRDKICTVWDLETKSPKRTVPVYESVEAVVLFPDSSDIICQENDSQSLLFLTAGSKGILRVWDAATAVCVYGQTLPHIAEGNSTEEEANEHSLTHCL--LIPGQHQVATVTAEHNILMYDLQNLQLKKQFAGYNDEVLDVKFLGPSDSHIVVATNSPQLKVF------DLETSN---------CQILY-GHTETVLALDVFKKGLLFASCAKDRTIRVWRMKKATGKVTCVAQGSGHTNGVGTISCSRMKEAFLVSGSQDYTIKLWKLPESLANKQSKGNSGDLETLLACATEKAHDKDINSVTVSPNDKLIASGSQDKTAKLWS----ATDLSLLGVFRGHKRGIWCVQFSNVDQVLASTSADGTLKLWGLQDFSCLKTFEGHDASVLKVVFVSRGAQLLTSGSDGLLKLWTIKTNECVKTLDTHEDKVWGLHCNREDDALVTG----SADSAIILWKDVTETELAEEQAKEDE 660          

Query:   72 FQLFDKFHSFYNAGKNICVTSDG-FIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSD----FMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQ-MQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVH--------YSIEDCLAVLSLKGNQLTRKSCFS----KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNL--EKSKLDR 2033
            + +  K  +FY  GK + + SDG +I+   G  +N +D  +      I Q ++  E++T F  +PDD  ++   + L+LK  D        + W + H AP+ TM  + +ST L TGG DS ++IW +     K +C    K     +++++ HP +  + + SS +D+ I  WD +T K L V   H  +VT + F    N M +S RD+   +W+ E  +    +PV ES+E  V+  D       + ++ + L +  G+ GI++    +  V +       + E   T +   + S    +  ++     +  V    NI  Y  Q +QL+ + +G   +V D+  +G +   I+V  ++P +++F      + E  N         CQ+++ GH++ + ++ VF  GL   S  KD  + +W+++ +      +       N + +  C   K  F+           + + + LA    KGN    ++  +    K H   I+++ ++ N  L+A+GS+DK  KLWS    + +L + GV +GHKR I  V+FS+ +Q+L + S D  +KLW ++  +CL+ F+   A V + +F +   Q+++  SDG + +W   T +     D H+ ++       + D         S+ S + L++D TE  L  E++K D 
Sbjct:   12 YAVTRKIEAFYKGGK-VQINSDGTYILCTCGNKLNILDIATGAVTYTIEQDDQ--EDITSFALSPDDEILVTGSRALLLKQWDWKQ-GTCSRTWKAIHTAPVATMTFDPTSTLLATGGCDSTIKIWDVI----KQYCTHNLKGSSGVVHLVQFHPDMSRLQLFSSSMDYKIRLWDLKTSKCLCVMETHFSAVTSLCFSPDGNTMISSGRDKICTVWDLETKSPKRTVPVYESVEAVVLFPDSSDIICQENDSQSLLFLTAGSKGILRVWDAATAVCVYGQTLPHIAEGNSTEEEANEHSLTHCL--LIPGQHQVATVTAEHNILMYDLQNLQLKKQFAGYNDEVLDVKFLGPSDSHIVVATNSPQLKVF------DLETSN---------CQILY-GHTETVLALDVFKKGLLFASCAKDRTIRVWRMKKATGKVTCVAQGSGHTNGVGTISCSRMKEAFLVSGSQDYTIKLWKLPESLANKQSKGNSGDLETLLACATEKAHDKDINSVTVSPNDKLIASGSQDKTAKLWS----ATDLSLLGVFRGHKRGIWCVQFSNVDQVLASTSADGTLKLWGLQDFSCLKTFEGHDASVLKVVFVSRGAQLLTSGSDGLLKLWTIKTNECVKTLDTHEDKVWGLHCNREDD----ALVTGSADSAIILWKDVTETELAEEQAKEDE 659          

Query:   72 FQLFDKFHSFYNAGKNICVTSDG-FIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSD----FMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQ-MQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVH--------YSIEDCLAVLSLKGNQ---LTRKSCFS-KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEK 2018
            + +  K  +FY  GK + + SDG +I+   G  +N +D  +      I Q ++  E++T F  +PDD  ++   + L+LK  D        + W + H AP+ TM  + +ST L TGG DS ++IW +     K +C    K     +++++ HP +  + + SS +D+ I  WD +T K L V   H  +VT + F    N M +S RD+   +W+ E  +    +PV ES+E  V+  D       + ++ + L +  G+ GI++    +  V +       + E   T +   + S    +  ++     +  V    NI  Y  Q +QL+ + +G   +V D+  +G +   I+V  ++P +++F      + E  N         CQ+++ GH++ + ++ VF  GL   S  KD  + +W+++ +      +       N + +  C   K  F+           + + + LA    KGN     T  +C + K H   I+++ ++ N  L+A+GS+DK  KLWS    + +L + GV +GHKR I  V+FS+ +Q+L + S D  +KLW ++  +CL+ F+   A V + +F +   Q+++  SDG + +W   T +     D H+ ++       + D         S+ S + L++D TE  L +
Sbjct:   14 YAVTRKIEAFYKGGK-VQINSDGTYILCTCGNKLNILDIATGAVTYTIEQDDQ--EDITSFALSPDDEILVTGSRALLLKQWDWKQ-GTCSRTWKAIHTAPVATMTFDPTSTLLATGGCDSTIKIWDVI----KQYCTHNLKGSSGVVHLVQFHPDMSRLQLFSSSMDYKIRLWDLKTSKCLCVMETHFSAVTSLCFSPDGNTMISSGRDKICTVWDLETKSPKRTVPVYESVEAVVLFPDSSDIICQENDSQSLLFLTAGSKGILRVWDAATAVCVYGQTLPHIAEGNSTEEEANEHSLTHCL--LIPGQHQVATVTAEHNILMYDLQNLQLKKQFAGYNDEVLDVKFLGPSDSHIVVATNSPQLKVF------DLETSN---------CQILY-GHTETVLALDVFKKGLLFASCAKDRTIRVWRMKKATGKVTCVAQGSGHTNGVGTISCSRMKEAFLVSGSQDYTIKLWKLPESLANKQSKGNSGDLETLLACATEKAHDKDINSVTVSPNDKLIASGSQDKTAKLWS----ATDLSLLGVFRGHKRGIWCVQFSNVDQVLASTSADGTLKLWGLQDFSCLKTFEGHDASVLKVVFVSRGAQLLTSGSDGLLKLWTIKTNECVKTLDTHEDKVWGLHCNREDD----ALVTGSADSAIILWKDVTETELAE 654          

Query:   87 KFHSFYNAGKNICVTSDGFIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYH----KSKINILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKAS---LFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFS-------------KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            K   FY  GK     +  ++    G  +N +D  S   LR + Q ++  E++T F  +PDD  ++ A + L+L            ++W + H AP+ +M  + +ST L TGG D  VR+W I Q  G     T+H       ++++  HP    +++ SS +D  I  W  +    L V + H  +VT + F E  + M +S RD+  I+W+ +++     +PV ES+E  V++      PE  A    +G  S  +  ++   + I++ ++ AS   ++   +   + ++ +     R+     D L+ V    N+  Y +  +QL+ + +G   +V D+  +G +   I+V  ++P +++F  ++                 CQ++H GH+  + ++ VF  G    S  KD  + IW++  + +  +  +         V ++C  R  +   V  S +DC   L      L  KS  +             + H   I+++ ++ N  LLATGS+D+  KLW+      +  + GV  GH+R + +V+FS T+Q+L TAS D  IKLW ++  +CL+ F+   A V +  F +   Q++S  SDG + +W   + +     D H+ ++         D    G     S S + L++D TE    + +  RE+Q  ++QEL+NLL E +++ AL LAI L++P      + AI  + E  A E + A  L  + D  +A           L  F V W TN+R C   + V+G++L   A  EL ++      + A   Y+++H++R +    +  F D+L
Sbjct:   20 KIEPFYKGGKAQLDQTGHYLFCVCGTKVNILDVASGALLRSLEQEDQ--EDITSFDLSPDDEVLVTASRALLLAQWAWRE-GTVTRLWKAIHTAPVASMAFDATSTLLATGGCDGAVRVWDIVQHYG-----THHFRGSPGVVHLVAFHPDPTRLLLFSSAVDTSIRVWSLQDRSCLAVLTAHYSAVTSLSFSEGGHTMLSSGRDKICIVWDLQSYQTTRTVPVFESVEASVLL------PEQPA--PALGVKSSGLHFLTAGDQGILRVWEAASGQCVYTQPQMPGLRQELTHCTLARA----ADLLLTVTADHNLLLYEAHSLQLQKQFAGYSEEVLDVRFLGPSDSHIVVASNSPCLKVFELQTL---------------ACQILH-GHTDIVLALDVFRKGWLFASCAKDQSIRIWKMNKAGQ--VACVAQGSGHTHSVGTICCSRLKESFLVTGS-QDCTVKLWPLPEALLAKSTAADSGPVLLQAQTTRRCHDKDINSLAVSPNDKLLATGSQDRTAKLWAL----PQCQLLGVFTGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGSQLLSSGSDGLLKLWTIKSNECVRTLDAHEDKVWGLHCSQLDDHAITG----GSDSRIILWKDVTEAEQAEEQAKREEQVIKQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPE--ACEKLEATVLRLRRDQKEA-----------LLRFCVTWNTNSRHCHEAQAVLGVLLRHEAPEELLAYDGVRGSLEALLPYTERHFQRLSRTLQAATFLDFL 784          

Query: 1503 HSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTC-------LQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSW 2381
            H   I+++ ++ N  LLATGS+D+  KLW+      +  + GV  GH+R + +V+FS T+Q+L TAS D  IKLW ++  +C       LQ F+   A V +  F +   Q++S  SDG + +W   + +     D H+ ++         D    G     S S + L++D TE    + +  RE+Q  ++QEL+NLL E +++ AL LAI L++P      + AI  + E  A E + A  L  + D  +A           L  F V W TN+R C   + V+G++L   A  EL ++
Sbjct:    9 HDKDINSLAVSPNDKLLATGSQDRTAKLWALP----QCQLLGVFTGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKVLCLSLQTFEGHDASVLKVAFVSRGSQLLSSGSDGLLKLWTIKSNECVRTLDAHEDKVWGLHCSQLDDHAITG----GSDSRIILWKDVTEAEQAEEQAKREEQVIKQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPE--ACEKLEATVLRLRRDQKEA-----------LLRFCVTWNTNSRHCHEAQAVLGVLLRHEAPEELLAY 288          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDC-LAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYN-NEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTL 1919
            GH   ITS     +  QI +   D  + +W ++  A+         V   D+V+S+    +G  +          L VL  KG     KS   K H+  + +++ + +  LL T S+DK++K+WS     ++  +  + + H   +   KFS   +L+++ S DK IK+W   +  C+ +F         + +N N   I S  SD  + +W+    K    + +H   ++C + 
Sbjct:   16 GHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHAR-----AYRYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKG-----KSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSM---FRQRFLYSLYR-HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSF 236          

Query: 1497 KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQ-IISCHSDGTMIVWN 1853
            K H   I++ + + N   +AT S D  + LWS K  ++         GHK  ++S++FS    LL +AS D+ ++LW ++      +FK+ TA  R++ ++ + Q +++   D ++ VW+
Sbjct:   15 KGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAY----RYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWS 130          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDC-LAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYN-NEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTL 1919
            GH   ITS     +  QI +   D  + +W ++  A+         V   D+V+S+    +G  +          L VL  KG     KS   K H+  + +++ + +  LL T S+DK++K+WS     ++  +  + + H   +   KFS   +L+++ S DK IK+W   +  C+ +F         + +N N   I S  SD  + +W+    K    + +H   ++C + 
Sbjct:   16 GHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHAR-----AYRYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKG-----KSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSM---FRQRFLYSLYR-HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSF 236          

Query: 1497 KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQ-IISCHSDGTMIVWN 1853
            K H   I++ + + N   +AT S D  + LWS K  ++         GHK  ++S++FS    LL +AS D+ ++LW ++      +FK+ TA  R++ ++ + Q +++   D ++ VW+
Sbjct:   15 KGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAY----RYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWS 130          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDC-LAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYN-NEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTL 1919
            GH   ITS     +  QI +   D  + +W ++  A+         V   D+V+S+    +G  +          L VL  KG     KS   K H+  + +++ + +  LL T S+DK++K+WS     ++  +  + + H   +   KFS   +L+++ S DK IK+W   +  C+ +F         + +N N   I S  SD  + +W+    K    + +H   ++C + 
Sbjct:   16 GHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHAR-----AYRYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKG-----KSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSM---FRQRFLYSLYR-HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSF 236          

Query: 1497 KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQ-IISCHSDGTMIVWN 1853
            K H   I++ + + N   +AT S D  + LWS K  ++         GHK  ++S++FS    LL +AS D+ ++LW ++      +FK+ TA  R++ ++ + Q +++   D ++ VW+
Sbjct:   15 KGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAY----RYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWS 130          

Query:   87 KFHSFYNAGKNICVTSDGFIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYH----KSKINILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKAS---LFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFS-------------KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            K   FY  GK     +  ++    G  +N +D  S   LR + Q ++  E++T F  +PDD  ++ A + L+L            ++W + H AP+ +M  + +ST L TGG D  VR+W I Q  G     T+H       ++++  HP    +++ SS +D  I  W  +    L V + H  +VT + F E  + M +S RD+  I+W+ +++     +PV ES+E  V++      PE  A    +G  S  +  ++   + I++ ++ AS   ++   +   + ++ +     R+     D L+ V    N+  Y +  +QL+ + +G   +V D+  +G +   I+V  ++P +++F  ++                 CQ++H GH+  + ++ VF  G    S  KD  + IW++  + +  +  +         V ++C  R  +   V  S +DC   L      L  KS  +             + H   I+++ ++ N  LLATGS+D+  KLW+      +  + GV  GH+R + +V+FS T+Q+L TAS D  IKLW ++  +CL+ F+   A V +  F +   Q++S  SDG + +W   + +     D H+ ++         D    G     S S + L++D TE    + +  RE+Q  ++QEL+NLL E +++ AL LAI L++P      + AI  + E  A E + A  L  + D  +A           L  F V W TN+R C   + V+G++L   A  EL ++      + A   Y+++H++R +    +  F D+L
Sbjct:   20 KIEPFYKGGKAQLDQTGHYLFCVCGTKVNILDVASGALLRSLEQEDQ--EDITSFDLSPDDEVLVTASRALLLAQWAWRE-GTVTRLWKAIHTAPVASMAFDATSTLLATGGCDGAVRVWDIVQHYG-----THHFRGSPGVVHLVAFHPDPTRLLLFSSAVDTSIRVWSLQDRSCLAVLTAHYSAVTSLSFSEGGHTMLSSGRDKICIVWDLQSYQTTRTVPVFESVEASVLL------PEQPA--PALGVKSSGLHFLTAGDQGILRVWEAASGQCVYTQPQMPGLRQELTHCTLARA----ADLLLTVTADHNLLLYEAHSLQLQKQFAGYSEEVLDVRFLGPSDSHIVVASNSPCLKVFELQTL---------------ACQILH-GHTDIVLALDVFRKGWLFASCAKDQSIRIWKMNKAGQ--VACVAQGSGHTHSVGTICCSRLKESFLVTGS-QDCTVKLWPLPEALLAKSTAADSGPVLLQAQTTRRCHDKDINSLAVSPNDKLLATGSQDRTAKLWAL----PQCQLLGVFTGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGSQLLSSGSDGLLKLWTIKSNECVRTLDAHEDKVWGLHCSQLDDHAITG----GSDSRIILWKDVTEAEQAEEQAKREEQVIKQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPE--ACEKLEATVLRLRRDQKEA-----------LLRFCVTWNTNSRHCHEAQAVLGVLLRHEAPEELLAYDGVRGSLEALLPYTERHFQRLSRTLQAATFLDFL 784          

Query:   87 KFHSFYNAGKNICVTSDGFIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYH----KSKINILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLK---TIRSILQTIDSLIFVRESDNIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFS-------------KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            K   FY  GK     +   +    G  +N +D  S   +R + Q ++  E++T F  +PDD  ++ A + L+L            ++W + H AP+ +M  + +ST L TGG D  VR+W I Q  G     T+H       ++++  HP    +++ SS +D  I  W  +    L V + H  +VT + F E  + M +S RD+  I+W+  ++     +PV ES+E  V++      PE  A  + +G  +  +  ++   + I++ ++ AS     +        SGL+   T  ++ +    L+ V    N+  Y ++ +QL+ + +G   +V D+  +G N   I+V  ++P +++F  ++                 CQ++H GH+  + ++ VF  G    S  KD  + IW++  + +  +  +         V ++C  R  +   V  S +DC   L      L  K+  S             + H   I+++ ++ N  LLATGS+D+  KLW+      +  + GV  GH+R + +V+FS T+Q+L TAS D  IKLW ++  +CL+ F+   A V +  F +   Q++S  SDG + +W   + +     D H+ ++         D    G     S S + L++D TE    + +  RE+Q  ++QEL+NLL E +++ AL LAI L++P      + AI  + E  A E + A  L  + D  +A           L  F + W TN+R C   + V+G++L   A  EL ++      + A   Y+++H++R +    +  F D+L
Sbjct:   20 KIEPFYKGGKAQLDQTGRHLFCVCGTKVNILDVASGDLIRSLEQEDQ--EDITAFDLSPDDEVLVTASRALLLAQWAWRE-GTVARLWKAIHTAPVASMAFDATSTLLATGGCDGAVRVWDIVQHYG-----THHFRGSPGVVHLVAFHPDPTRLLLFSSAVDTSIRVWSLQDRSCLAVLTAHYSAVTSLSFSEDGHTMLSSGRDKICIVWDLRSYETSRTVPVFESVEASVLL------PEEPA--LALGVKNSGLHFLTAGDQGILRVWEAAS----GQCVYTQPQMSGLRQELTHCTLARAAGLLLTVTADHNLLLYEARSLQLQKQFAGYSEEVLDVRFLGPNDSHIIVASNSPCLKVFELQTLA---------------CQILH-GHTDIVLALDVFRKGWLFASCAKDQSIRIWRMNKAGQ--VACVAQGSGHTHSVGTICCSRLKESFLVTGS-QDCTVKLWPLPEALPSKNTASDGDLIPLQAQSTQRCHDKDINSLAVSPNDKLLATGSQDRTAKLWAL----PQCQLLGVFSGHRRGLWNVQFSPTDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGAQLLSSGSDGLLKLWTIKSNECVRTLDAHEDKVWGLHCSRLDDHAITG----GSDSRIILWKDVTEAEQAEEQAKREEQVIKQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPE--ACEKLEATVLRLRRDQKEA-----------LLRFCITWNTNSRHCHEAQAVLGVLLRHEAPEELLAYDGVRGALEALLPYTERHFQRLSRTLQAATFLDFL 784          

Query:   66 THFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYH----KSKINILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESD-NIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCL--------AVLSLK-----GNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            T++ +  K   FY  GK     +   +    G  +N ++  S   LR + Q ++  E++T F  +PD+  ++ A + L+L        S   ++W + H AP+ TM  + +ST L TGG D  VR+W I +  G     T+H       ++++  HP    +++ SS  D  I  W  +    L V + H  +VT + F    + M +S RD+  IIW+ ++      +PV ES+E  V++ +   +P     +  +G  S  +  ++   +  ++ ++ AS               G +     L     ++    +D N+  Y ++ ++L+ + +G   +V D+  +G     ++V  ++P +++F               +L    CQ++HG H+  + ++ VF  G    S  KD  V IW++  + ++    +         V +VC  R  +   V  S +DC         A+LS       G  L +     + H   I+++ +  N  LLATGS+D+  KLW+      +  + GV  GH+R +  V+FS  +Q+L TAS D  IKLW ++  +CL+ F+   A V +  F +   Q++S  SDG + +W     +     D H+ ++         D    G    +S S + L++D TE    + +  +E+Q   +QEL+NLL E +++ AL LAI L++P      + AI  + E  A E + A  L  + D  +A           L  F V W TN+R C   + V+G++L   A  EL ++      + A   Y+++H++R +    +  F D+L
Sbjct:   13 TNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRSLEQEDQ--EDITAFDLSPDNEVLVTASRALLLAQWAWQEGSV-TRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYG-----THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPE---EP-----VSQLGVKSPGLYFLTAGDQGTLRVWEAAS--GQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF---------------ELQTSACQILHG-HTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQV--MCVAQGSGHTHSVGTVCCSRLKESFLVTGS-QDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALP----QCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTG----ASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPE--ACEKLEATMLRLRRDQKEA-----------LLRFCVTWNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAFLDFL 784          

Query:   87 KFHSFYNAGKNICVTSDGFIISDDGESINYIDKNS---LRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYH----KSKINILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESD-NIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCL--------AVLSLKGNQLTRKSCFSKP------HSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQI---DCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            K   FY  GK     +   +    G  +N +D  S   LR + Q ++  E++T F  +PDD  ++ A + L+L        S   ++W + H AP+ TM  + +ST L TGG D  VR+W + +  G     T+H       ++++  HP    +++ SS  D  I  W  +    L V + H  +VT + F    + M +S RD+  +IW+  +      +PV ES+E  V++      PE  A  + V  A     T      + + E            A       G +     L     L+    +D N+  Y ++ ++L  + +G   +V D+  +G     ++V  ++P +++F                L    CQ++HG H+  + ++ VF  G    S  KD  + +W++  S ++    +         V ++C  R  +   V  S +DC         A+LS KG        F +       H   I+++ +  N  LLATGS+D+  KLW+         + G   GH+R +  V+FS  +Q+L TAS D  IKLW ++  +CL+ F+   A V +  F +   Q++S  SDG + +W     +     D H+ ++    C  L      + R    AS  S + L++D TE    + +  RE+Q  ++QEL+NLL E +++ AL LAI L++P      + AI  + E  + E +    L  + D  +A           L  F V W TN+R C   + V+G++L   A  EL ++      +     Y+++H++R +    +  F D+L
Sbjct:   20 KIEPFYKGGKVQLDQTGQHLFCVCGTRVNILDVASGAVLRSLEQEDQ--EDITAFDLSPDDKVLVTASRALLLAQWAWQEGSV-TRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDVVRCYG-----THHFRGSPGVVHLVAFHPDPARLLLFSSAADTSIRVWSLQERSCLAVLTAHYSAVTSLTFSADGHTMLSSGRDKICVIWDLRSLQATRTVPVFESVEAAVLL------PEEPAPELGVKSAGLHFLTAGDQGALRVWEAASGRCVH----AQQRLRGPGRELTHCTLAHAAGLLLSVTADHNLLLYDARSLRLRKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF---------------DLQTSACQILHG-HTDIVLALDVFRKGRLFASCAKDQSIRVWRMNKSGEV--ACVAQGSGHTHSVGTICCSRLKETFLVTGS-QDCTVKLWPLPEALLS-KGTGHEGGPVFLQAQATQHCHDKDINSVAVAPNDKLLATGSQDRTAKLWALP----RCQLLGTFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLLKLWTIKNNECVRTLDAHEDKVWGLHCSRL------DDRALTGASD-SRVVLWKDVTEAEQAEEQAKREEQVVKQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPE--SCEKLETTVLQLRRDQKEA-----------LLRFCVTWNTNSRHCHEAQAVLGVLLRHEAPDELLTYDGVRASLEGLLPYTERHFQRLSRMLQAATFLDFL 784          

Query:  195 RKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVD--RSNLSKHPKIWNS-------CHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIG--------QGEG---KSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQMQLE-----YELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQL--VHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQ--VEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIED-CLAVLSLKGNQLTRKSCFS-------KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT-AVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            R I   ++T E +     + DDY   +A  +   K++   RS L    +I +         H+ P+ TM ++ ++T L TGGA+  V++W I         +G G    + C   H++             V++S   D  +  WD  + + + VF GH   + G+ F    + + + SRD+TV +WN +  + +  IPV  S+E    V+    QPE             I+ T      ++  ++K  S  +      ++   S    I  ++   ++ +    SD      K++  E      +L+G+  +V D   +G +              L  C +   TE+    D +S    Q+  V  GH+  + ++    DG+ + +G KD  V +W   +ED+    + + T        V+   +D  G   ++  S +D  L   +L G+QL  KS FS       K H   ++ ++++ +  ++A+ S+DK +KLW   T      + GVL+GH+R + +  F+   + L + S D+ I++W V++  C+Q  +  T A+ + ++ +   Q++S  +DG + VW+  +G+  +  D H+ ++  + L +  DG+     +  + +++ +++D TE+ + K   + E++ + EQ L+N      +  A+ LA+ L++P         +     QP         +    D+   +  L   +L  LF     W TN++T ++ + ++ ++L   +   L         + +   Y+D+H  R N+    +   DY+
Sbjct:   41 RIIGTRSETGERLFSIKKDEDDYVTALAITSDSKKLIAAFRSRLLTIYEIPSGRRIKSMKAHETPVITMTIDPTNTLLATGGAEGLVKVWDIAGAYVTHSFRGHGGVISALCFGKHQN-----------TWVLASGADDSRVRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFLLSGSRDKTVQVWNIKKRSAVRTIPVFHSVEAIGWVN---GQPEEK-----------ILYTAGEGNLILAWDWKSGSRLD----PGVDTTHSETNAIIQVVPFSENTLLSVHSDLSLLLRKRVPGEGFITIKKLNGSFDEVIDCAWIGDD-------------HLAVCSN---TEF---IDVISTDGTQVFGVLEGHTDIVLTLDSSEDGVWLATGAKDNTVRLWNLNIEDNVYKCIHVFTGHTASVTAVALGPLDVNGYPTFLASSSQDRTLKRFNL-GSQLN-KSDFSNRAVWTIKAHDRDVNAIQVSKDGRIIASASQDKTIKLWDSSTGE----VVGVLRGHRRGVWACSFNPFSRQLASGSGDRTIRIWNVDTQQCVQTLEGHTGAILKLIYISQGTQVVSAAADGLVKVWSLSSGECVATLDNHEDRV--WALASRFDGSL--LVSGGADAVVSVWKDVTEEYIAKQAEELERRVEAEQLLSNFEQTEDWQQAIALALSLDRPHGLLRLFERVMTAPHQPN-------SITGNKDVDNVLVQLPDHQLIILFQRIRDWNTNSKTSMVAQRLLRLLLHSYSPEHLLKLSGIKDILDSMIPYTDRHLARVNDLIEDSYIVDYV 776          

Query:   72 FQLFDKFHSFYNAGKNICVTSDGFII-SDDGES-----INYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVS-----DFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTI--------DSLIFVRESDNIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVED-------SAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLK--------------GNQLTRKSC-FSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKT-KSK-ELIIK--GVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKS-PTAVHRAMFYNNEKQIISCHSDGTMIVWN------------RDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAIN--------DNNEQPA-DEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYLGDAVTGFNII 2513
            FQL  +F   ++    I VTSDG ++ S DGE        ++D    + ++ FN   EE+TCF A+P D T+I+A K L L  +DR    K  K W+S H  PI  + +N++STRL TG  D  +RIWH+G+ EG    C  H SKI +LR H   N++ SS++ + ++V WD+E G Q+    GHQ +V+ I F E  ++  T   D+  I W+ E F K+ + PV+ESL +   +      + +     D   ++ GG  G+++     + V   E +  SLF + ++  +N+   GL ++ +I +          D L+ VR+S ++EFY +  +++  +  G +  V  + ++G+ K  +++ +++  ++ F         + + +     W C+LV G H+  I+ ++V S G  +VSGG D  + +W +E+       SA+L + L       +  VS+VC  R  K ++   S +  L V ++                  L R+ C     HS  I+++ ++IN   LAT S+DK VK+WS  + KS+ EL+ K  G L GH R + SV+FSD E++ LTAS D+ ++LW ++  TC++  +     V+RA F +  +QI+SC   G + +WN             D       F+ H G+I    +  D     +GF      + +C ++D+TE+  + S    ++  + +Q+L NL    +FV AL LA++L+KP   +  L  I+        +  + P    A+     P      +   S +L++   L  +AV W T  RTCLI + +   ++   A  +L +WP+ +  I A   Y+ +HY+R N         DY+ D      I+
Sbjct:   15 FQLGSRFLPRFSEAGQIYVTSDGEVLCSRDGEEQLEIFTRHLDGTEWQPLSVFN---EEITCFYASPYDKTIILASKGLYLLKIDRQT-RKLVKKWSSSHTKPISVIHMNRTSTRLATGSGDCCIRIWHVGEREGYVASCKVHTSKITLLRFHNSKNLLFSSALGEVELVVWDSENGNQVATLVGHQGAVSEIAFSETGSEFVTCGHDKVFIQWSSETFEKVRVFPVLESLTSISYLPKGSLVNHLGSSVHDKTFIVTGGQWGVLRVWDTERAVCALEVRGPSLFSDADS--LNRLGFGLHSVSTIQRFTVPCLPGCSDVLMVVRQSSHVEFYNTATLKVFNQFIGEIGPVTQLCLMGRAKSHLVLADASSNLKFFPSPPHCPATFPSAAS----WTCRLVQGPHTNVISDLAVSSCGRWLVSGGHDQSLCVWYLEETDKEGSISARL-VPLFFGKEFHDAHVSAVCFSRDAKTVF-SASTDGVLKVWTMSVDPADVSEFCDGKLSPDLLREGCSIHNAHSGAINSLHVSINGKFLATASRDKTVKIWSLDSGKSRSELMPKPIGSLIGHSRGVWSVRFSDFERVALTASSDRDLRLWNLKDFTCIRTLEGHGEPVYRAEFISKGRQILSCDQKGLVRLWNLAKKDRVASMVSNDNLTTPGVFEAHQGRIWALEICPDG----QGFYTGGEDATICHFKDKTEETAQDSLAVMQEFVKTQQQLENLCKRKQFVKALHLAVRLDKPQRAFEILQEIDLLDGLSTTEGKQHPLFGRALLGLVEPVVGSHPQQAPSDELSQ--RLLRYAVNWNTRARTCLIAQRIFNWIVTHWAPEKLLTWPDMAKTIEAMVPYTVRHYQRFNRLEEQLAVLDYVFDQSRNHQIL 878          

Query:   72 FQLFDKFHSFYNAGKNICVTSDGFIIS----DDGESINYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVI--VSDFMNQP-----EADAYLVMVGGASGIIKTVSPSKRVIIQEFK------KASLFENIETADINKDKSGLKTIRSI----------------LQTIDSLIFVRESDNIEFYSKQM-QLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLF------ACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDS--------------AKLRLKLITSIVVENDI-VSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRK-------SCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKS-PTAVHRAMFYNNEKQIISCHSDGTMIVW--------NRDTGKDSSK----------FDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAI-----------NDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTE----LRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRR 2441
            F+L DKF   +N+   I  T  G I      DD   IN +D+NS   +N+  +  E +T FV +     + +A KNL+LK  D S+  +  K+W SCH+  +  M LNK STRL TG  D  VR+WHIG  EG S  C  H+  I +L+ HP L  + SSS+ D  +  WDTETGK +    GHQ  VT +DF+    ++ T  RD+ +I+W+  +F K  +IP  ESLE CV   V    N       E++  L++ GG  G ++         + E K        S   ++ T D +    GL +I  +                  +   LI VR+S+++EFY   + +L  E  G++  V  + I GKN + +++ +++P+M++F      + K     E   +S     W C L+ GGH   I  ++V + G  I SG KD  + +W + +S                ++L LIT I   +   +SSVC DR    + +  S +  L V +++ N L +        +     H  +I+++++++++ L+AT S+DK VK+W +K +S  L  +GVL+GH+R + SV FS  E+++LTAS D  ++LW ++  +C++  +     V++A+F +++KQI+SC   G + +W        N++ G++  K          ++ HDG+I    +  D      GF        +C + D TE  L ++   +E+  Q +QEL+NL+ +  +  A+ LA+KL++P  T + L  +           N+ N +   +A     + D  D  K   + +L +     + L S+A+ W T  RT +I ++V+  +L      EL  WP ++  I     Y+ +HY+R
Sbjct:    7 FKLADKFQPCFNSQYPIFPTESGNIYCGRDVDDSLCINVLDENSFALVNRI-QDDELITSFVVDEAGSEIFIATKNLLLKRFD-SSAPRPTKVWMSCHQRIVQKMALNKFSTRLATGSGDMVVRLWHIGPKEGFSTSCRLHQGMITLLKFHPTLPYLFSSSVGDHFVAVWDTETGKHVSSLEGHQSIVTSLDFNVAKKELVTCGRDKVLIVWSSVDFTKQKVIPTFESLEACVFLPVGALTNHLGHKFFESNTSLLLTGGQWGCLRCWDVDTGHCVLEIKGPLDRTPQSDSGSLTTLDRHSIDYGLHSISHLNVYNVKDNNDNVLDESKNSFLRLILVRQSNHVEFYDPMVGKLTAEFLGDIGQVDQLCIAGKNHNYLILADASPHMKIFLNPYGLSSKGKNTIEGNLNSKTNGSWKCHLIPGGHIDVIMDLTVSTCGQWIASGSKDQSICLWHLIESEDSTSSSLHKSSKNVPVKLDLITQIHKAHAAHISSVCFDRLTTHL-ISSSEDGILKVWNVQCNNLDKPDTVLSELNTIHGAHCGVINSIDVSVDNRLVATASRDKTVKIWEFKKQS--LHCQGVLQGHRRGVWSVCFSRFEKIVLTASGDGDVRLWNLKDFSCIRTLEGHDQPVYKAVFLSHDKQILSCDQKGLIRLWNISKPPKNNQEKGENIVKPSSEENSSLVYEAHDGRIWSLAICPDES----GFFTGGEDETLCYFEDITEILLNETSQQQEEYIQTQQELDNLVHKQMYADAVHLAVKLDQPKRTLDILQELLTQDLVKETCKNNQNMKYPTQAGNLLSVLD--DFVKKSHNENLNDSLSLSQRLLSYAINWNTRTRTSMISQFVLNWILTRWTPEELIEWPNFNQAIQYLLPYTTRHYQR 881          

Query:  150 SDDGESINYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVS-----DFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETAD----INKDKS----GLKTI-----RSILQTIDS-------------LIFVRESDNIEFYSK-QMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACK-SFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVED---SAKLRLKLITSIVVENDI------VSSVCVDRKGKFIY------------VHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKS-PTAVHRAMFYNNEKQIISCHSDGTMIVWN---------RDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNN---EQPADEAIGAFE--------------LPDKTDMGKAVKSLDLTE----LRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYLGDAVTGFNIIDLTMDS 2531
            +DD   I  +  ++  K+       +++T +  + D+ T+ +A KNLMLK ++  ++ K  K+W S H  PIF M ++   TRL T   DS VR+WH+G  EG S  C  H S   +LR HP    + SS++ D+++V W+TETG +LG   GHQ  VTG+ F++  N + T  RD+ +++W+C  F +  +IP  ESLE CV +      + + +      L++ GG  G ++   P+    + E  K  L     TAD     +KD+     GL +I       +  T DS             LI VR+S+++EFY   + +L  E  G++  V  + IVGK+ + +L+ +++P+++LF           E D +    W C LV GGH   IT ++V + G  IVSG KD  + +WQV D   +   +  L   I+V+  +      +S+VC ++    +             V+++  D     +L   +L   S     H   ++ +++++N  L+AT S+DK VK+W+      + +  GVL+GH+R + SV FS  E+++LTAS D  ++LW ++  +C++ F+     V++A+F +N++QI+SC   G + +WN          D+      F+ H+G+I    +  D      GF        +C ++D T++ +E+    +E+  Q  Q L+NL+ + +F  ALRL++KL++P  T + L  +   +    Q A++ + +                L   T   KA    + T     ++ L ++AV W T  RT +I + V+  ++      +L  WP  +  + +   Y+ +HY+R +         DYL D      + D+   S
Sbjct:  140 TDDAVRITALSGHTFTKLASLFD-DDKITSYAVSTDNTTIFVALKNLMLKKIEYPSM-KTTKVWQSFHHRPIFRMAVSTDGTRLATSSNDSTVRLWHLGPKEGFSATCRAHNSMPTLLRFHPDRPYLFSSALGDYNVVVWNTETGAKLGSLDGHQSQVTGLCFNDDGNFIVTCGRDKVIMVWSCPEFQRRNIIPAFESLEACVFLPTGALINHLGESVRSEQLLLTGGQWGCLRVWHPTTGRCLLEV-KGPLDRAPVTADGTVLTSKDRESIDYGLHSIVDLQLAHVFPTPDSSTSSESPTDLLPKLILVRQSNHVEFYDPMRAKLTAEFLGDIGQVDQLCIVGKSHNRLLLADASPHLKLFVNPCGLSACSKEMDEEGKGSWSCHLVPGGHEDVITDLTVSTCGQWIVSGSKDQSLCLWQVVDRDLTLSGKGPLAKVILVKRLLNAHSAHISAVCFNKSTNLLISSADDNVLKAWTVNFNKPDVQNNANLHSVELAEWSVVHNAHQACVNAIDVSVNDQLVATASRDKTVKIWTVTKTGLDCL--GVLQGHRRGVWSVCFSAREKVVLTASGDGDVRLWNLKDFSCIRTFEGHEQPVYKAVFLSNDRQILSCDQKGLVRLWNVSKPGMTETSDSSTGCKVFEAHEGRIWSIAVCPDES----GFYTGGEDETLCYFKDVTQQIVEERSKKQEEFIQTRQILDNLIQQKQFAEALRLSVKLDQPKRTLDLLQDLLLMDEDMSQKANDKVKSVRYSGHVAKLETALNGLLRPTASSKAFHEDNYTSSEHLVQRLLTYAVNWNTRVRTSVIAQAVLNWIVTTWTPEQLLRWPGIARTVESLLPYTVRHYQRVSRLEEQLAILDYLCDVADEHQVGDIVESS 1009          

Query:   69 HFQLFDKFHSFYNAGKNICVTSDGFIIS----DDGESINYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSN---LSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSD------FMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKK-------ASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFY-SKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKL--RLKLITSIVVEN---DIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQ----------LTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYK--TKSKELIIK--GVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKS-PTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSS------------KFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAIN----------DNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYLGDAVTGFNIIDLT 2522
            HF+   +F   Y+    I +  DG ++     D    +    + +  +  +     +E+  +V  P D T+I A KN+ L   DRS+   LSK    WNS H  PI  + LN S+TRL TG  D  +RIWHIG  EG    C  H SKI +LR HP   ++ S SM + D++ W+TETG ++    GHQ +VT I F     Q AT   D+ V++W+ EN ++  +IP  ESL+T   +          ++   DA  ++ GG  GI++  +      + E +        ++  +N++    +  +  L  + +  +  + L+  R+S ++E Y +  ++L +E  G +  V  + +VG   + +++ +++  ++LF           + +     W CQLV   H   I  ++  + G  +++GG D  +S+WQ+ +   L  R KL++    +N     +S+V   R    ++   S +  L   S+              L         H   I+ M +++N   LATGS+DK  K+WS +  T   +++ +  G L GH R + SV FSD E++LLTAS DK ++LW ++ L+C++ F+     V++A+F +  +QI+SC   G + +WN  +  +S+              + H+G+I    +  D      GF      + +C +RD ++   +   +  E+ T+  QE +NLL   +F  ALRLA+KL+KP  TY  L+ I+              +P ++A+    +P+  + G+A  S ++ +   L  +AV W T  RTCL+ + V   ++   A   L +WP  +  + AF  Y+ +HY+R N         DYL D      II+ T
Sbjct:    8 HFEKKSQFLPHYSDPCPIFLCDDGAMVCGRDFDAQMQVFMCHQPNSWEFAKVGAIDDEINTYVVCPFDNTIIFATKNMFLHRFDRSSQRILSK----WNSYHTKPICLLALNNSATRLATGSTDGTIRIWHIGDREGFVASCKLHTSKITLLRFHPAKALLFSCSMGEVDLIVWNTETGAKVTTLVGHQGNVTDIAFSPSEEQFATCGHDKVVLLWSTENMHRTKIIPTFESLQTLAYLPPGSLSNHLPSKANRDASFLITGGQWGIVRVWNTKTSQCVLELRGPTNHSSDSAALKNLDFGMHSVSRLTLFHVSAFPENPEVLLLTRQSSHVELYNADTLKLFHEFVGEIGPVDKLCLVGAQGNRLVLADASANLKLF-------VRPPSATSSSGSWACQLVQSPHFGVIGDMAASTCGQWLLTGGHDQSLSLWQLIEPEDLSGRPKLLSRFFAKNAHDAHISAVSFARDTSVVF-SASTDGILKTWSVHQQPSEASDDVTCTLNEGQSVRNAHDGAINCMHVSVNGKFLATGSRDKTAKIWSLESVTTGGDMLPRLVGSLVGHSRGVWSVCFSDHERVLLTASGDKDLRLWNLKDLSCIRTFEGHEEPVYQAVFISKGRQILSCDQRGLVRLWNLSSKGESTLAAASKDARPPNVLEAHEGRIWTIAVCPDET----GFYTGGEDATICFFRDTSDDTAQDRAVTMEEFTKIHQEFDNLLKSKRFSEALRLAVKLDKPQRTYEILHEISLLEGISPGDGAGVHRPLEKALFGL-IPEPPEPGQA-PSEEMAQ--RLLKYAVNWNTRARTCLVAQRVFNWIISNWAPERLLAWPGIANSVTAFIPYTVRHYQRLNRLEEQMAVLDYLFDESRCNQIIEWT 868          

Query:   72 FQLFDKFHSFYNAGKNICVTSDGFIISDDGES------INYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVS-----DFM--NQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSI-LQTIDS-------LIFVRESDNIEFYSKQ-MQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQV---EDSAKLRLKLITSIVVE---NDIVSSVCVDRKGKFIYVHYSIEDCLAVLSL----------KGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWS----YKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKS-PTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSK----------FDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAI------------NDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYLGD 2489
            FQL  +F  +++    I +  DG ++    E        +++ +N     +  N   +E+T +VANP+D TV +A K+L L   DR    K    WNS H   I  + LN ++TRL TG  D  +RIWHIG  EG    C  H SKI +LR HP   +++S S+ + D+V W+TETG ++    GHQ +VT I F  L  Q  T   D+ +I+W+ +   ++ +IP  ESL+  V +      D +  N  E  +YL+  GG  GI++         + E +  +   +   A  N D  GL ++  + L  + +       L+  R S ++EFY+ + ++L YE  G +  V  + ++G  ++ +++ + +P ++LF+      +   + S       CQLV   H+  I  ++V S GL +++GG D  + +WQ+   E+SA  RL+L++    +   +  +S+VC  R    ++   S +  L    L          K N           H   I+ + ++ N   LATGS+DK  K+WS       K  +  + G L GH+R + SV+FSD E++LLTAS DK ++LW ++ +TC+  F+     V+RA F +  +QI+SC   G + +WN     ++S            + H G+I    +  D      GF      + +C + D++E +  +S    E+  +  QEL NLL   K   ALRLA+KL+KP  T+  L  I              ++ +P + A+  F L  K        S ++ +   L  +AV W T  RTCL+ + V+  ++   A   L  WP     + AF  Y+ +HY+R           DYL D
Sbjct:    9 FQLKSRFSPYFSDPNPIFLCDDGVMLCGRDEDARIRLFTSHLGRNEFGDCDGLN---DEITAYVANPNDNTVFLATKSLFLARYDRCE-HKVLSRWNSSHSRTIGVIALNATATRLATGSNDCSIRIWHIGNCEGFVASCRCHTSKITLLRFHPTEPLLMSCSLGEVDVVVWNTETGAKVATLQGHQGNVTDIAFSPLDEQFTTCGHDKVIIVWSTKTMKRVKVIPAFESLQAMVYLPVGSLRDRISSNANEGKSYLI-TGGQWGIMRLWCTWTSRCVLEVRGPTSHSSDSAAASNLD-FGLHSVSHLSLFHVSAFPDNPYILVLSRRSSHVEFYNAETLKLFYEFIGEIGSVDQLCLMGAARNRLVLTDVSPNLKLFSNPPSSTSSSGSWS-------CQLVQSPHTGVIGDMAVSSCGLWLLTGGHDQTLCLWQLVEPEESAG-RLRLLSKACTKEAHDAHISAVCFARDSSAVF-SASTDGVLKTWELNLGVVDKPDEKTNVFEEGRSVRNAHDGAINCVHVSSNGRFLATGSRDKTAKIWSLDLLLAGKDMQPKLIGSLIGHRRGVWSVRFSDHERVLLTASGDKDLRLWNLKDMTCIHTFEGHEEPVYRAEFISKGRQILSCDQRGLVRLWNLSKKNNTSAVSYDKISPNVVEAHQGRIWTIAVCPDNG----GFYTGGEDATICFFEDKSEDSARESAATVEEFIRTHQELENLLKSKKHRRALRLAVKLDKPQRTFEILQEILFTEGFITVDVGKGSSLRPFERAL--FSLVPKPSAPGEAPSEEMAQ--RLLKYAVHWNTRARTCLVAQRVLNWVVSNWAPERLLRWPGIGHAVAAFIPYTARHYQRLGRLEEQMAVMDYLFD 856          

Query:   66 THFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNSLRKINQFNKTSEE-MTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHPLLNMV-VSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVS---DF--MNQPEADAYLVMVGGASGIIKT-VSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDS-LIFVRESDNIEFYS-KQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVH---------YSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            T++ +  K   FY  GK      +  I+   G  +N ++  + + I+   +  +E +T F  +PDD  ++ A + L+LK  D     K  + W + H  P+ +M  + +ST L TGG D  +++W +     K +C    K     ++++  HP +N++ + SS +D  I  WD  T K + V   H  +VT + F    + + +S RD+   +W+ +       +PV E++E  VI+    DF  +     D + V   G+ G+++   S S R +  +   ++   N E AD +     L  +  +   +   L  V    NI  Y    + ++ +  G   D+ D+  +GK+   I+V  ++  +++F               +L+   CQ+++G H+  +  + VF       S  KD  V +W++ D    R+  +      ++ V S+   R  K   V          + + D L     +  QL  +    K H   ++++ ++ N  L A+GS+D+  KLWS      ++ + GV +GH+R I  V+FS  +Q+L TAS D  IKLW +   +CL+ F+   A V + +F +   Q++S  SDG + +W   T +    FD H  ++          G        S+ S + +++D TE+ L + +  +E Q  ++QEL+NLL E K++ AL +AI L++P      +  I  + + P        +L ++T +      L   +   L  +   W TN R+CL  + V+ ++L  ++ AEL  +    T +     Y+ +H +R      S+ F DY+
Sbjct:   11 TNYAVSSKIEPFYKGGKVQISHDEKIILCSCGPRLNILEIATGKIIHSIEQDDQEDITSFSLSPDDEMLVTASRALLLKQWDWRQ-EKCTRSWRAIHNVPVASMTFDCTSTLLATGGCDGTIKLWDVV----KQYCTHNLKGSSGVVHLVEFHPDINLLQLFSSSMDCSIRIWDLRTSKCICVLESHYSAVTSLAFSPDGHTLISSGRDKICSVWDLKERKVKRTVPVYEAVEGVVILPENEDFSELGVKSKDLHFV-TAGSKGVLRVWESSSARCVFTQTLPSAPVSNPEQADGDP----LSLVYCLPMPLSKRLATVTAEHNILLYQLPSLSVQQQFVGYNDDILDVRFLGKDDSHIVVATNSSQLKVF---------------ELATSSCQILYG-HTDTVLCLDVFRKRSMFASCAKDKSVRVWKM-DPESGRVHCVAQGHGHSNAVGSISCSRLKKAFLVSGSQDCTVKVWDLPDTLPAAGEEPAQLEAR-VTEKAHDKDVNSVAISPNDKLFASGSQDRAAKLWSLT----DMSLLGVFRGHRRGIWCVQFSPVDQVLATASADGSIKLWGLHDFSCLKTFEGHDASVLKIIFVSRGTQLVSGGSDGLVKLWTIKTNECIKTFDAHQDKVWAL----HGSGKDDLMVTGSADSNITVWKDVTEEELAEEQAKQENQILKQQELSNLLHEKKYLKALGIAISLDQPHTVLRVIKEIRQDEKGP--------QLLEETLL-----KLRRDQKEALLRYCAVWNTNARSCLDAQAVLQVLLTHLSPAELLQFQGARTHLEGLIPYTGRHMQRIGRLLQSSMFLDYM 790          

Query:  267 VIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHPLLNMV-VSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVS---DF--MNQPEADAYLVMVGGASGIIKT-VSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDS-LIFVRESDNIEFYS-KQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVH---------YSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            ++ A + L+LK  D     K  + W + H  P+ +M  + +ST L TGG D  +++W +     K +C    K     ++++  HP +N++ + SS +D  I  WD  T K + V   H  +VT + F    + + +S RD+   +W+ +       +PV E++E  VI+    DF  +     D + V   G+ G+++   S S R +  +   ++   N E AD +     L  +  +   +   L  V    NI  Y    + ++ +  G   D+ D+  +GK+   I+V  ++  +++F               +L+   CQ+++G H+  +  + VF       S  KD  V +W++ D    R+  +      ++ V S+   R  K   V          + + D L     +  QL  +    K H   ++++ ++ N  L A+GS+D+  KLWS      ++ + GV +GH+R I  V+FS  +Q+L TAS D  IKLW +   +CL+ F+   A V + +F +   Q++S  SDG + +W   T +    FD H  ++          G        S+ S + +++D TE+ L + +  +E Q  ++QEL+NLL E K++ AL +AI L++P      +  I  + + P        +L ++T +      L   +   L  +   W TN R+CL  + V+ ++L  ++ AEL  +    T +     Y+ +H +R      S+ F DY+
Sbjct:    2 LVTASRALLLKQWDWRQ-EKCTRSWRAIHNVPVASMTFDCTSTLLATGGCDGTIKLWDVV----KQYCTHNLKGSSGVVHLVEFHPDINLLQLFSSSMDCSIRIWDLRTSKCICVLESHYSAVTSLAFSPDGHTLISSGRDKICSVWDLKERKVKRTVPVYEAVEGVVILPENEDFSELGVKSKDLHFV-TAGSKGVLRVWESSSARCVFTQTLPSAPVSNPEQADGDP----LSLVYCLPMPLSKRLATVTAEHNILLYQLPSLSVQQQFVGYNDDILDVRFLGKDDSHIVVATNSSQLKVF---------------ELATSSCQILYG-HTDTVLCLDVFRKRSMFASCAKDKSVRVWKM-DPESGRVHCVAQGHGHSNAVGSISCSRLKKAFLVSGSQDCTVKVWDLPDTLPAAGEEPAQLEAR-VTEKAHDKDVNSVAISPNDKLFASGSQDRAAKLWSLT----DMSLLGVFRGHRRGIWCVQFSPVDQVLATASADGSIKLWGLHDFSCLKTFEGHDASVLKIIFVSRGTQLVSGGSDGLVKLWTIKTNECIKTFDAHQDKVWAL----HGSGKDDLMVTGSADSNITVWKDVTEEELAEEQAKQENQILKQQELSNLLHEKKYLKALGIAISLDQPHTVLRVIKEIRQDEKGP--------QLLEETLL-----KLRRDQKEALLRYCAVWNTNARSCLDAQAVLQVLLTHLSPAELLQFQGARTHLEGLIPYTGRHMQRIGRLLQSSMFLDYM 713          

Query: 1194 LWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTL 1919
            L+PC L   GH   +TS+    +  QIV+G  D  V IW ++   +         V   D V SV     G+   V  +  D    L + G  +  +S   + H+  + ++  + +   L T S DK VK+W+   + K L     L  H   +   KFS   +L+++AS D+ +K+W   S  C+  F   +  V+ A F+ +   I +  +D T+ VW+  T K    + +H   ++  + 
Sbjct:    2 LYPCWLNFKGHRDTVTSIDFNCNMKQIVTGAMDSCVMIWNLKPQMR-----AYRFVGHKDAVMSVQFSPSGRL--VASASRDKTVRLWVPG--VKGESTVFRAHTGTVRSINFSSDGQSLVTASDDKTVKVWTVH-RQKFLF---SLCQHINWVRCAKFSPDGRLIVSASDDRTVKIWDKNSRECIHSFCEHSGFVNCADFHPSGTCIAAGGTDNTVKVWDIRTNKLLQHYQVHSAVVNSLSF 231          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT-AVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNC 1943
             HS  ++S+ +   G  + +GG+D +V+IW V      +   I S+      V  V      + + V  S    L V  L+  ++ R       H   I +++ +     +A+GS D N+KLW  + K    + +   KGH + +  + FS   + L +AS D  IKLW + +   + +F + T AV+   F+ NE  + S  +D T+ +W+ +  K     +   G + C  ++   DG+C
Sbjct:   18 AHSSKVSSLVLGKSGRLLATGGEDCRVNIWAVN-----KPNCIMSLTGHTSPVQCVQFSSTEEQV-VAGSESGSLRVWDLEAAKILRTLMG---HKANICSLDFHPFGEHIASGSVDTNIKLWDVRRKG--CVFR--YKGHTQAVRCISFSPDGKWLASASDDSTIKLWDLTAGKLITEFTAHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFKLIGSSEGETGPVRC--MLFSPDGSC 244          

Query:  351 HKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFC---CTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWN 698
            H + + ++ L KS   L TGG D +V IW +     K  C    T H S +  ++       VV+ S     +  WD E  K L    GH+ ++  +DFH     +A+ S D  + +W+
Sbjct:   19 HSSKVSSLVLGKSGRLLATGGEDCRVNIWAVN----KPNCIMSLTGHTSPVQCVQFSSTEEQVVAGSE-SGSLRVWDLEAAKILRTLMGHKANICSLDFHPFGEHIASGSVDTNIKLWD 132          

Query:  351 HKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLI 722
            HKA I ++  +     + +G  D+ +++W + + +G  F    H   +  +   P    + S+S  D  I  WD   GK +  F+ H  +V  + FH     +A+ S D TV +W+ E F KLI
Sbjct:  103 HKANICSLDFHPFGEHIASGSVDTNIKLWDVRR-KGCVFRYKGHTQAVRCISFSPDGKWLASASD-DSTIKLWDLTAGKLITEFTAHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKF-KLI 223          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT-AVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNC 1943
             HS  ++S+ +   G  + +GG+D +V+IW V      +   I S+      V  V      + + V  S    L V  L+  ++ R       H   I +++ +     +A+GS D N+KLW  + K    + +   KGH + +  + FS   + L +AS D  IKLW + +   + +F + T AV+   F+ NE  + S  +D T+ +W+ +  K     +   G + C  ++   DG+C
Sbjct:   55 AHSSKVSSLVLGKSGRLLATGGEDCRVNIWAVN-----KPNCIMSLTGHTSPVQCVQFSSTEEQV-VAGSESGSLRVWDLEAAKILRTLMG---HKANICSLDFHPFGEHIASGSVDTNIKLWDVRRKG--CVFR--YKGHTQAVRCISFSPDGKWLASASDDSTIKLWDLTAGKLITEFTAHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFKLIGSSEGETGPVRC--MLFSPDGSC 281          

Query:  351 HKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFC---CTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWN 698
            H + + ++ L KS   L TGG D +V IW +     K  C    T H S +  ++       VV+ S     +  WD E  K L    GH+ ++  +DFH     +A+ S D  + +W+
Sbjct:   56 HSSKVSSLVLGKSGRLLATGGEDCRVNIWAVN----KPNCIMSLTGHTSPVQCVQFSSTEEQVVAGSE-SGSLRVWDLEAAKILRTLMGHKANICSLDFHPFGEHIASGSVDTNIKLWD 169          

Query:  351 HKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLI 722
            HKA I ++  +     + +G  D+ +++W + + +G  F    H   +  +   P    + S+S  D  I  WD   GK +  F+ H  +V  + FH     +A+ S D TV +W+ E F KLI
Sbjct:  140 HKANICSLDFHPFGEHIASGSVDTNIKLWDVRR-KGCVFRYKGHTQAVRCISFSPDGKWLASASD-DSTIKLWDLTAGKLITEFTAHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKF-KLI 260          

Query:  405 TGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHPLLNMV-VSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQP----EADAYLVMVGGASGIIKT--VSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQT-----IDSLIFVRESDNIEFYS-KQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCL-------AVLSLKGNQLTRKSC--FSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKT----KSKELIIKG---VLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYS----DQHYRRENEQTNSTGFNDY 2480
             G +D+ +++W I     K +C    +     + ++  HP  +   V S+  D  I  WD ++G       GH  +VT + F      + ++ RD  V++W  E       +PV E LE  V++ +  +Q     +      +  G+ G ++    + ++ V      +A    +   A       G    R+I+Q      +  +  V    NI  ++   + +  +  G   +V D+  +GK    + V  ++  +++F   S                 CQL+HG H   + ++ V   G  + S  KD  V +W +E+++   ++ +         V +V   R      V  S +DC          LS  G   T  +C    K H   ++++ ++ N  L+A+GS+D  V+LW+       + +   ++G   VL+GH+R + SV                  +LW +    CL+ F+   A V + +F     Q+++  SDG + +W   T +     D HDG++       D +    G     S + + L++D T++  E+ +   E+Q  + QEL+NLL E K++ ALRLAI L++P  T   + AI D             E   + D+   +  L   +  +L  FAV W TN+R+C     V+  +   ++  +L  +      + A   YS    ++H++R      +  F DY
Sbjct:    8 AGSSDATIKVWDIV----KQYCTHNFRGSSGVVGVVAFHPDTSCPRVLSAASDCKIRVWDLQSGACSATLDGHYSAVTALRFACDGRTLLSAGRDSVVLLWELEAGVVRKTVPVYEPLEDLVVLPEEGDQSALGVQGKGIHFVTAGSKGTLRVWDAANARCVFTAPPPEAGSPGDDAAAAAASAGPGDGAERTIVQAHLVPALGQIAAVTSDHNIILHALGGLTVAKQFVGYNDEVLDVKFLGKTDSHVAVATNSAQIKIFQLDSSH---------------CQLLHG-HRDMVLALDVSRRGTMLASSSKDRTVRVWSMEEASG-HVRCVAVATGHAHAVGAVAWSRLKDGFLVSGS-QDCTLKLWDLPKGLSPSGTATTALTCRFTEKAHDKDVNSVAVSPNDRLVASGSQDHTVRLWAVAAKKKKEEEGGGLRGPVAVLRGHRRGVCSV------------------RLWGLHDFACLKTFEGHDASVLKVVFVARGTQLLTSGSDGLVKLWTIKTNECVRTLDAHDGKVWGLHGSRDDERVLTG----GSDACIVLWKDVTQEEQEEERKKEEEQLLKRQELSNLLHEKKYLKALRLAISLDQPHTTLTVIQAILD-------------ETGGREDLEATIAKLRQDQKESLLKFAVTWNTNSRSCHEAHAVLTTLFRHVSPGDLLRFANVQPAVEALLPYSALVTERHFQRMGRLLQAAMFVDY 679          

Query: 1497 KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQII-SCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDT 1931
            K H++ +  +  +++  +LA+ S D  VKLW ++  S E +    + GH   +SSV F      L++AS DK +K+W V++  C++ F       R +  N +  +I SC +D T+ VW   T +  ++   H+  ++C +   D 
Sbjct:   86 KGHTDSVQDISFDLSGKMLASCSADMTVKLWDFQ--SFECL--RTMHGHDHNVSSVAFMPNGDHLVSASRDKTMKMWEVQTGYCVKTFTGHREWVRMVRPNQDGSLIASCSNDQTVRVWVTATKECKAELREHEHVVECVSWAPDA 227          

Query: 1503 HSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIH 1892
            H + ++ +  +   S++ + S+D  +K+W Y+T   E      LKGH   +  + F  + ++L + S D  +KLW  +S  CL+        V    F  N   ++S   D TM +W   TG     F  H
Sbjct:   46 HRSPVTRVIFHPVFSVIVSASEDATIKVWDYETGDFER----TLKGHTDSVQDISFDLSGKMLASCSADMTVKLWDFQSFECLRTMHGHDHNVSSVAFMPNGDHLVSASRDKTMKMWEVQTGYCVKTFTGH 172          

Query:  459 KSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKL 719
            + +  + H+S +  +  HP+ +++VS+S  D  I  WD ETG       GH DSV  I F      +A+ S D TV +W+ ++F  L
Sbjct:   39 EKYALSGHRSPVTRVIFHPVFSVIVSASE-DATIKVWDYETGDFERTLKGHTDSVQDISFDLSGKMLASCSADMTVKLWDFQSFECL 124          

Query: 1428 SIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDF-KSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDG---QID 1907
            S++ CL V + K    TR   F   H + + +++ + +  L+ + S+DK V+LW    K +      V K H   + SV FS   Q L+TAS DK IK+W V     L    +    V  A F  + + I+S   D T+ VW+ ++ +    F  H G   Q+D
Sbjct:   37 SMDACLMVWNFKPQ--TRAYRFVG-HKDAVMSVQFSPSGHLVVSASRDKTVRLWVPSVKGEST----VFKAHTATVRSVSFSADGQSLVTASDDKSIKVWTVHRQKFLYSLNQHSNWVRSAKFSPDGRLIVSGSDDRTVRVWDSNSRECVHTFYEHGGFVNQVD 193          

Query:  600 FSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKT-VSPSKRVIIQEF--KKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDN--IEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKR 1649
            F GH+D++T +DF+    Q+A+ S D  +++WN                           +P+  AY   VG    ++    SPS  +++     K   L+      +    K+   T+RS+  + D    V  SD+  I+ ++   Q            K +  + ++ + +   + +P  RL    S + T    DS+          HGG    +  V     G  I + G D  V +W +  +     KL+    V    V+S+     G ++ +  S +  L VL L   +L         H    + +  +      A+G  D+ V +W  KT    +    VL+ HK+
Sbjct:   14 FKGHRDTITSVDFNPNMKQLASGSMDACLMVWNF--------------------------KPQTRAYR-FVGHKDAVMSVQFSPSGHLVVSASRDKTVRLWVPSVKGESTVFKAHTATVRSVSFSADGQSLVTASDDKSIKVWTVHRQ------------KFLYSLNQHSNWVRSAKFSPDGRLIVSGSDDRTVRVWDSNSRECVHTFYEHGGF---VNQVDFHPSGTCIAAAGTDNTVKVWDIRMN-----KLLQHYQVHGAAVNSLSFHPTGNYL-ITASNDSTLKVLDLVEGRLFYT---LHGHQGPATAVAFSRAGDFFASGGSDEQVMVW--KTNFDSVDYSEVLRSHKQ 315          

Query:  387 SSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCE 704
            +   L  G  D  VR+  +  GE K    T H++ I  L  HP    +VS S  D D++ WD      L    GH+D+VT   F    N + T S+D  V  W+ +
Sbjct:   88 AGVELAAGHVDGAVRLLSLITGE-KRVTFTGHRTAITALAYHPDGTRLVSGSQ-DTDVIVWDVVGECGLYRLKGHKDAVTSARFFSTKNVLLTGSKDSFVKFWDLD 191          

Query: 1503 HSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGV--LKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQ 1754
            H   I+ +  + + + L +GS+D +V +W    +       G+  LKGHK  ++S +F  T+ +LLT S D  +K W +++  C +
Sbjct:  118 HRTAITALAYHPDGTRLVSGSQDTDVIVWDVVGEC------GLYRLKGHKDAVTSARFFSTKNVLLTGSKDSFVKFWDLDTQHCFK 197          

Query: 1206 QLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIY---VHYSI-------EDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAM--FYNNEKQIISCHSDGTMIVWNRDTG 1865
            Q VH  +    T   +   G ++VSG +D  + +W +E    L        V+   + +  CV   G+ +      Y++       E CL  L              + H+N + +++   +   + +GS D ++++W  +T +        L GH+   S ++  D   +L++ + D  +K+W +++  CLQ  + P     A+     + K +++   DGT+ +W+  TG
Sbjct:  305 QCVHTLYGHTSTVRCMHLHGNRVVSGSRDATLRVWDIETGQCLH-------VLAGHVAAVRCVQYDGRRVVSGAYDYTVKVWDPESETCLHTL--------------QGHTNRVYSLQ--FDGVHIVSGSLDTSIRVWDAETGT----CLHTLVGHQSLTSGMELRD--NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFSRKLVVTSSDDGTVKLWDLRTG 507          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKL-----ITSIVVENDIVSSVCVDR--------KGKFIYVHYSIEDCLAVLSLKGNQLTRKS--------------CFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGK 1868
            GH   + +   F  G +IVSG  D  + +W       LR  +     + S  +  +I+ S   DR         G+ ++  Y     +  + L GN++   S              C      ++ +   +  +   + +G+ D  VK+W  ++++        L+GH   + S++F      +++ SLD  I++W  E+ TCL       ++   M   +   ++S ++D T+ +W+  TG+
Sbjct:  231 GHDDHVITCLQFC-GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRGNIIVSGSTDRTLKVWNADTGQCVHTLYGHTSTVRCMHLHGNRVVSGSRDATLRVWDIETGQCLHVLAGHVAAVRCVQYDGRRVVSGAYDYTVKVWDPESET----CLHTLQGHTNRVYSLQFDGVH--IVSGSLDTSIRVWDAETGTCLHTLVGHQSLTSGMELRDNI-LVSGNADSTVKIWDIKTGQ 465          

Query:  162 ESINYID-----KNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKM--VDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLN---MVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQ------MATSSRDETVIIWNCENFN------KLILIPVMESLETCVIVSD-----FMNQPEADAYLVMVGGASGII--KTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQL-VHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQV-EDSAKLRL--------KLITSIVVENDIVS----SVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSK-PHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT-AVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDY 2480
            + IN ID     +  L KI+  N+  +E+T     PD   +    +  +LK+  +    + +  KI      +P + +  + +ST L  GG D  + +  I  G   +     H   I+ L+ +  LN    +++S   +  +  WD    K L     H  +V G+D  E+ +       + +  RD+ + +W+   FN       L  +PV + +E+C  + D      +     DA   ++   SG +  +T  P + + I       +  N +   +  D++        LQ    LI V E  +++     +Q+   ++GN   + D+  VG   + + +  ++P +R+         E        +  P  + ++ GH   + S+    DGL I +  KD    +W+  E+S K  +          +T++ + N IVS       +          + I    A + +   Q+ + S +++  H   I+ + ++ N S+ AT S DK  K+W+ +    E      L  HKR +  V F   ++LL T+S DK +K+W +++ + ++  +  T AV R  F N +KQ+ISC +DG + +W+  +G+     D H+ ++  + L T  DG+     +A +  +   ++D TE+ +E+ +   + Q ++EQ L N + +  + +A  LA+ L+ P+  +N L      +    D   G  E+    ++ +A+  L+  +L  L      W TN +T  I +  I  +L     A+L+  P     + A   Y+ +H+ R +     +   DY
Sbjct:   38 DEINIIDLTPGSRKILHKIS--NEDEQEITALKLTPDGQYLTYVSQAQLLKIFHLKTGKVVRSMKI-----SSPSYILDADSTSTLLAVGGTDGSIIVVDIENGY-ITHSFKGHGGTISSLKFYGQLNSKIWLLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDDIINLWD---FNMKKKCKLLKTLPVNQQVESCGFLKDGDGKRIIYTAGGDAIFQLIDSESGSVLKRTNKPIEELFI--IGVLPILSNSQMFLVLSDQT--------LQ----LINVEE--DLKNDEDTIQVTSSIAGNHGIIADMRYVGPELNKLALATNSPSLRIIPVPDLSGPE--------ASLPLDVEIYEGHEDLLNSLDATEDGLWIATASKDNTAIVWRYNENSCKFDIYAKYIGHSAAVTAVGLPN-IVSKGYPEFLLTASNDLTIKKWIIPKPTASMDV---QIIKVSEYTRHAHEKDINALSVSPNDSIFATASYDKTCKIWNLENGELE----ATLANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRL--WALSTMNDGDM--IVSADADGVFQFWKDCTEQEIEEEQEKAKLQVEQEQSLQNYMSKGDWTNAFLLAMTLDHPMRLFNVLKRALGESRSRQDTEEGKIEVIFNEELDQAISILNDEQLILLMKRCRDWNTNAKTHTIAQRTIRCILMHHNIAKLSEIPGMVKIVDAIIPYTQRHFTRVDNLVEQSYILDY 808          

Query: 1515 ISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWN 1853
            ++ +E+  +  LLAT    +NV+L+  +T +   +     +GH+  ++SV F    + ++T+S D  IK+W V S +  +++K    V+  + + N+ ++ISC  DG + +W+
Sbjct:   35 VNRLEITNDKKLLATAGH-QNVRLYDIRTTNPNPVAS--FEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYKHNAPVNEVVIHPNQGELISCDRDGNIRIWD 144          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLR----LKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDC-----------LAVLSLK--GNQL----TRKSCFS------------KP------HSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLW 1727
            GH  ++TSVS   D   +V+  +DG + +W V   +  R       +  +V+  +    +  DR G           C           L  LS+   G+ L    T+ +C+             KP      HS  I+ + ++ +   LAT S D   ++WS     K   ++  L GH+R +    FS     L+TAS D  ++LW
Sbjct:   73 GHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYKHNAPVNEVVIHPNQGELISCDRDGNIRIWDLGENQCTHQLTPEDDTSLQSLSMASDGSMLAAANTKGNCYVWEMPNHTDASHLKPVTKFRAHSTYITRILLSSDVKHLATCSADHTARVWSIDDDFK---LETTLDGHQRWVWDCAFSADSAYLVTASSDHYVRLW 277          

Query:  396 RLTTGGADSKVRIWHIGQG---------EGKSF------CCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNC 701
            R+ +G  DSK+ IW I +          +G+          T H  K+  +  HP+   V++SS  D+ +  W+ ETGK + +   H D VT + F    N +AT +RD+ + +WN 
Sbjct:   96 RIASGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPVKFLTGHARKVGHVLYHPVAENVLASSSGDYTVKLWNVETGKDM-ITLKHPDMVTSMSFSYDGNYLATVARDKKLRVWNI 211          

Query:  108 AGKNICVTSDGFIISDDGESINYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCL---NKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLN---MVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENF 710
            AGK I    +  I+  D   I   + N+  K+  F    + +     +P    V+    +L +K+ +  N     + +        F MC+    K  +   +G  D  V++W +GQ        T  +  +N +  +PL +   M+ +S   D  I  WD +T   +    GH  +V+   FH     + + S D T+ IWN   +
Sbjct:   60 AGKFIA-RKNWIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEH---FVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASD--DLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWNSSTY 260          

Query: 1503 HSNIISTMEMNI-NSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDT--EQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGK 1868
            H + +  +  N  + S  A+G  D+ VK+WS    +    +     G +R ++ V +     +  ++TAS D  IK+W  ++ +C+   +   + V  A+F+     IIS   DGT+ +WN  T K
Sbjct:  139 HEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLT---TGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWNSSTYK 261          

Query: 1203 CQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCF----SKPHS----------NIISTMEMNINSS-LLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGN--CRG 1949
            CQ    GH+  ++ V     GL + SG  D  V +W +                          + +G+ I +  S    +  LSL  +   R   F     KP +          N     + N NS  ++ T S D  + LW+   KS + I +  + GH++ ++ V FS   + +++AS D  IKLW       +  F+   A V++  + ++ + ++SC  D T+ VW+  T K S     H  ++  +T+    DG   C G
Sbjct:  270 CQYTMSGHTNSVSCVKWGGQGL-LYSGSHDRTVRVWDI--------------------------NSQGRCINILKSHAHWVNHLSLSTDYALRIGAFDHTGKKPSTPEEAQKKALENYEKICKKNGNSEEMMVTASDDYTMFLWN-PLKSTKPIAR--MTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEV--YTVDWSVDGKRVCSG 504          

Query:   66 THFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHP---LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWN-----CENFNKLILIPVMESLETCVIVSDFMN----QPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTI---RSILQTIDSLIFVRESDNIEFYS-------KQMQLE----------YELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCF----SKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPT-AVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAIND-----NNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYR 2438
            T++++  K  +FY  GK      + ++     + +  +   S + I+   + S+ ++CF A+PDD  ++ A KNL+L+  D  N     K W + H AP+ +MC + SST L TG +DS +++W I + +  +         +++++ HP   +L +  +S   D  I  WD    + L V   H   VT + F    + M +SSRD+ + IW+       N      IP  E +E+   +   ++    + + + Y V  G             R+     K   L   +   +   D SGL+ +    ++ +  + ++ +    NI  Y        KQ  +           ++  G   ++ D+   GK  D + VV ++  +RL+  ++ +               C++V  GHSK I  + V +DG +IV+G KD  V +W V D +  R   + +       VS V   R  +   +  S +  + V           S F     K H   I+++ ++ N  L+ TGS+DK  K+W    +  + I+ GV +GHKR +   +FS  ++ + TAS D  IK+W +   TC++ F+  + +V + +F +N  Q+I+  +DG + +W   T +    FD H  ++    +    +  C G A     S + L++D T++   K++ + E    +EQ+L+NL+ + ++  A+ LAI L KP   +  LN I D     N  Q  +  + +   PD+ DM              +  F V+W TN +  L  + V+ I+L   +  EL   P     I A   Y+   Y+
Sbjct:   16 TNYEVSSKIEAFYTGGKVQFSGDEEYLFCSCTDKVQVLHVESGKVIHSLKEESDIISCFAASPDDEFLVTAGKNLLLRQWDWRN-GMQTKTWKAVHVAPVSSMCFDASSTLLATGSSDSTIKVWDIIK-QYYTHSLKGSTGVVSLVKFHPDPKVLQLFSTSD--DCKIRVWDLVKSRCLCVLENHFSVVTSLAFDPSHSTMISSSRDKVLNIWDMADMLTPNRRPPRTIPCFEGVESVEFLPKGLSSKVCEKKDEQYFVTAGNKG----------RLCFWSLKSGQLVHKLVVVENMSDDSGLQQLLVHATLCRKRNVVMVITHDQNILMYDLENFKKLKQFSMRDTVNLLRIPHWQFVGYNDEILDMSFAGKTNDHLAVVTNSNQLRLYNLETLD---------------CRMVE-GHSKMILCLDVCADGTKIVTGSKDHTVRVWDVSDCSNPRCLAVGN--GHTHAVSGVAWSRTSQRFVISCSQDLTIKVWEATKKAAEESSMFVKMTVKAHDKDINSVAVSPNDKLVVTGSQDKTAKVW----RIADGILMGVARGHKRGVWCAQFSPFDKCIATASGDSTIKIWSLTDYTCVKTFEGHSNSVLKVVFISNGMQLITSGTDGLVKLWTIKTNECVQTFDEHQDKVWAIAVNKSQNAFCSGGAD----SAITLWKDVTQEERHKAQQEAEDVILKEQKLSNLVHDKRYSEAISLAISLEKP---FRVLNVIKDMLTAENGIQEINTTLRSLR-PDQIDM--------------ILKFIVEWNTNAKNTLASQTVMSIILRSTSPYELIDRPNMKDTIEALLPYTGMVYQ 790          

Query:  600 FSGHQDSVTGIDFHELSNQMATSSRDETVIIWNC---ENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTI--RSILQTIDSLIFVRESDN-IEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQ-----LVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDK-NVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCV-ESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWN-------------RDTG---KDSSKFDIHDGQID-CFT-LITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDR 2033
            ++GH D  T ID+          S+D T  I++    ENF+     PV  S     IV  F  +   DAY +   GA GI    +  + V ++   K    +  +  ++ K K G K    +     I S    + +   I  +S  +   +EL  + + ++ + I  +    + V  +  ++  F C S           +L +W  Q     L   GH  D+  ++   DG  I +GG DGKV +W       +      +    +  V++V     G+ + +  S++  +    L  N+      F+ P     ST+ ++ +  ++A GS+D   + +WS +T      +  VL GH+  +SS+ FS +  +L++ + DK ++LW V ES    +     + V       + +++     DG +  W+             RD G   K   K          CFT L    DG      A      +C+Y  E +  L++ ++ R
Sbjct:  140 YTGHYDDTTCIDWF-----FIVGSKDMTARIYSLDPMENFS-----PVTLSGARNTIVGCFFQEGSLDAYTISSSGALGIWTCSAKLQEVFLRTKDKNDQTDQ-DKEELVKWKKGPKHFFEKENFTEITSCALHKATQVLIVGFSNGVFTIHELP-DFNLIQTLSISQQTISAVAVNPTGEWL-AFGCTSL---------GQLLVWEWQSESYILKQQGHYYDMNVLAYSPDGNYIATGGDDGKVKLWNT-----MTGFCFVTFHEHSASVTAVTFSPNGQVV-LSASLDGTVRAFDL--NRYRNFRTFASPRPAQFSTLALDSSGEVVAAGSRDTFEIFVWSIQTGR----LLEVLAGHEAPVSSLAFSPSHPVLISGAWDKTVRLWNVFESKVSRETLNLTSDVVSIAVRPDGREVAISSLDGALTFWDLEAAVQVKSVDGRRDLGAGRKADDKITARSSAFGKCFTSLCYTADG--ENVLAGGRSKFVCIYNVEQQILLKRFQVSR 612          

Query: 1221 GHSKDITSVSV-FSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSM 1976
             H  +I  +S+  S G  +V+GG+D KV++W V         +I S+      V  V  +  G+ + V  S    L +  L+  ++ R       H + I +++ +     +A+GS D N+KLW  + K          KGH  C++ ++FS   + +++   D   KLW + +   + DFK  T  V+ A F+  E  + +  SD T+  W+ +T +  S        I C      TDG C    A  S+ +
Sbjct:   16 AHGSNINCLSLGPSTGRVMVTGGEDRKVNMWAVGQP-----NVIMSLAGHTSPVECVQFN-SGEDLVVAGSQSGTLKIWDLEAAKILRTLTG---HKSSIRSLDFHPFGDFVASGSLDTNLKLWDIRRKGCIF----TYKGHTDCVNHLRFSPDGRWIISGGEDGAAKLWDLTAGKIINDFKMHTGPVNCAEFHPKEFLLATGSSDRTVKYWDLETFELVSSTSPETHPIRCIGF--HTDGLCLFSGAQDSLKV 254          

Query:  348 CHKAPIFTMCLNKSSTR-LTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFK 878
             H + I  + L  S+ R + TGG D KV +W +GQ          H S +  ++ +   ++VV+ S     +  WD E  K L   +GH+ S+  +DFH   + +A+ S D  + +W+      +      +    CV    F      D   ++ GG  G  K    +   II +FK
Sbjct:   16 AHGSNINCLSLGPSTGRVMVTGGEDRKVNMWAVGQ-PNVIMSLAGHTSPVECVQFNSGEDLVVAGSQ-SGTLKIWDLEAAKILRTLTGHKSSIRSLDFHPFGDFVASGSLDTNLKLWDIRRKGCIF---TYKGHTDCVNHLRF----SPDGRWIISGGEDGAAKLWDLTAGKIINDFK 184          

Query:   87 KFHSFYNAGKNI-CVT---SDGFIISDDGE--SINYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSC--HKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENF 710
            K   F   G NI C++   S G ++   GE   +N         I      +  + C   N  +  V+   ++  LK+ D        KI  +   HK+ I ++  +     + +G  D+ +++W I + +G  F    H   +N LR  P    ++S    D     WD   GK +  F  H   V   +FH     +AT S D TV  W+ E F
Sbjct:   10 KLQEFVAHGSNINCLSLGPSTGRVMVTGGEDRKVNMWAVGQPNVIMSLAGHTSPVECVQFNSGEDLVVAGSQSGTLKIWDLEAA----KILRTLTGHKSSIRSLDFHPFGDFVASGSLDTNLKLWDIRR-KGCIFTYKGHTDCVNHLRFSPDGRWIISGGE-DGAAKLWDLTAGKIINDFKMHTGPVNCAEFHPKEFLLATGSSDRTVKYWDLETF 219          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDC-LAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTL 1919
            GH   +TSV    +  Q+V+G  D  + IW  +   +         V   D + SV     G  I      +   L V S+KG     +S   K H+  + +++ + +   L T S DK++K+W+   + K L     L  H   +   KFS   +L+++ S DK IKLW   S  C+  F  P   V+   F+ +   I +  +D T+ VW+    K    +  H G ++  + 
Sbjct:   16 GHRDTVTSVDFNPNMKQLVTGSMDSSLMIWHFKPHMR-----AYRFVGHKDAILSVKFSPSGHLIASASRDKTVRLWVPSVKG-----ESTVFKAHTATVRSVDFSGDGQSLLTASDDKSLKVWTVH-RQKFLY---SLNAHMNWVRCAKFSPDGRLIVSGSDDKTIKLWDRTSKDCVHTFYDPGGFVNSVEFHPSGTCIAAGGTDSTVKVWDIRMNKLLQHYQAHTGAVNSVSF 236          

Query: 1497 KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQ-IISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITD 1928
            K H + +++++ N N   L TGS D ++ +W +K   +         GHK  I SVKFS +  L+ +AS DK ++LW          FK+ TA  R++ ++ + Q +++   D ++ VW     K     + H   + C     D
Sbjct:   15 KGHRDTVTSVDFNPNMKQLVTGSMDSSLMIWHFKPHMRAY----RFVGHKDAILSVKFSPSGHLIASASRDKTVRLWVPSVKGESTVFKAHTATVRSVDFSGDGQSLLTASDDKSLKVWTVHRQKFLYSLNAHMNWVRCAKFSPD 155          

Query:  378 LNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTY--HKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKL 719
             + S T +  GG DS V++W I   +       Y  H   +N +  HP  N +VS+S  D  +   D   G+      GHQ   T + F       A+ S DE V++W   NF+K+
Sbjct:  194 FHPSGTCIAAGGTDSTVKVWDIRMNK---LLQHYQAHTGAVNSVSFHPSGNYLVSASS-DTTLKILDLMEGRLFYTLHGHQGPATSVVFSRNGEYFASGSSDEQVMVWKT-NFDKV 304          

Query: 1089 NKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQL-----VHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSC---FSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLD---KVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVW 1850
            +KD IL V+ +P   L A  S ++T        + LW   +     V   H+  + SV    DG  +++   D  + +W V      R K + S+    + V        G+ I V  S +  + +        T K C   F  P    ++++E + + + +A G  D  VK+W  +       +    + H   ++SV F  +   L++AS D   K++ L        L   + P      +F  N +   S  SD  ++VW
Sbjct:   59 HKDAILSVKFSPSGHLIASASRDKT--------VRLWVPSVKGESTVFKAHTATVRSVDFSGDGQSLLTASDDKSLKVWTVH-----RQKFLYSLNAHMNWVRCAKFSPDGRLI-VSGSDDKTIKLW-----DRTSKDCVHTFYDP-GGFVNSVEFHPSGTCIAAGGTDSTVKVWDIRMNK----LLQHYQAHTGAVNSVSFHPSGNYLVSASSDTTLKILDLMEGRLFYTLHGHQGPAT--SVVFSRNGEYFASGSSDEQVMVW 297          

Query:  207 QFNKTSEEMTCFVANP--------DDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINIL---RNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWN 698
            Q +  S E  CF  N         D+  +I + KN M   V    L+KH  +        I T   +  S  + TG  D  VR+WH+ +G+    C   HKS ++ L   +NH L     +S   D  I  WD++TG+ + + +GH   V    F    + +A++S D+TV +W+
Sbjct:   80 QGHTHSVETCCFSPNGAFLCSGSWDNTAIIWSLKNGMPTYV----LNKHRNV--------IQTCAFSHDSKTVATGSWDCTVRLWHLVEGDMAVKCLDGHKSNVHSLAFAKNHML-----ASGSWDMTIRLWDSKTGELIHLLTGHSGWVQACSFSGSGDLLASASDDQTVRVWD 237          

Query: 1224 HSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDG-TMIVWNRDTGK 1868
            H   I  V   SDG    S   D  V +W+         K +  +      V + C    G F+    S ++   + SLK    T        H N+I T   + +S  +ATGS D  V+LW       ++ +K  L GHK  + S+ F+    +L + S D  I+LW  ++   +      +   +A  ++    +++  SD  T+ VW+  TG+
Sbjct:   40 HDGAIKCVCFSSDGKLFASAAYDHLVMVWEAATG-----KQVFCLQGHTHSVETCCFSPNGAFL-CSGSWDNTAIIWSLKNGMPTY---VLNKHRNVIQTCAFSHDSKTVATGSWDCTVRLW--HLVEGDMAVK-CLDGHKSNVHSLAFAK-NHMLASGSWDMTIRLWDSKTGELIHLLTGHSGWVQACSFSGSGDLLASASDDQTVRVWDTSTGR 242          

Query: 1260 DGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFI----YVHYSIEDCLAVLSLKGNQLTRKSCFS-KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLW-CVE---SLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQI 1904
            D  ++V+GG D  V IW  +       K++ ++   +  +  VC    GK      Y H         L +     T K  F  + H++ + T   + N + L +GS D    +WS K          VL  H+  I +  FS   + + T S D  ++LW  VE   ++ CL   KS   VH   F  N   + S   D T+ +W+  TG+       H G +
Sbjct:   10 DWTRVVTGGDDDLVKIWDSKTG-----KVLFTLEHHDGAIKCVCFSSDGKLFASAAYDH---------LVMVWEAATGKQVFCLQGHTHSVETCCFSPNGAFLCSGSWDNTAIIWSLKNGMPTY----VLNKHRNVIQTCAFSHDSKTVATGSWDCTVRLWHLVEGDMAVKCLDGHKSN--VHSLAFAKNH-MLASGSWDMTIRLWDSKTGELIHLLTGHSGWV 212          

Query:   66 THFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNSLRKINQF-NKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIV---SDF--MNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENI--ETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYS-KQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDC-LAVLSLKGN-------QLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            T++ +  K   FY  GK      + +I    G  +N ++ ++ + ++   +   E++T F  + DD  ++ A + L+LK  D    S   + W + H  P+ +M  + SST L TGG D  +++W +     K +C    K     +++++ HP +  + + SS LD  I  WD  + + + V   H  SVT + F      M +S RD+   +W+         +P+ E++E  V++   +D   +     D++ +   G+ GI++    S    +   K  S   +   E  D + +  GL  +   L     +  V    NI  Y    +  + +  G   +V D+  +GKN   I+V  ++  +++F        E   +S       CQ++ G H+  + ++ VF  G    S  KD  V +WQ+ DS   ++  +       + V S+   R  K  +V    +DC + V  L  +       QLT ++   K H   ++++ ++ N  LLA+GS+D+  +LWS       + + GV +GH+R I SV FS  +Q+L T+S D   KLW ++  +CL+ F+   A V + +F +   Q+++  SDG + +W   T +     D H  ++         D        AS+ S + ++ D TE  L + +  +E Q  ++QEL+NLL E K++ AL LAI L++P      + AI    ++                  K +  L + +  +L  F V W TN R CL  + V+ ++L  +   EL  +    T +     Y+++H +R      ++ F +Y+
Sbjct:   10 TNYAVSSKIEPFYKGGKVQISNDEQYIFCTCGSRVNILEISTGKIVHCVEHDDQEDITSFAVSSDDELLVTASRALLLKQWDWRRASC-TRSWRAIHTVPVASMTFDSSSTLLATGGCDGTIKLWDVV----KQYCTHNLKGSSGVVHLVQFHPDISRLQLFSSSLDCGIRMWDLRSSQCVCVLQSHYSSVTSLSFSADGGTMVSSGRDKICTVWDLNTRQAKRTVPIYEAVEGVVLLPKDADLSQLGVKSKDSHFI-TAGSKGILRVWHASTARCVYTQKAPSTLSSATGEAEDQDDNPFGLTHL-FYLPASHRVATVTAEHNILLYQLPGLTTQQQFVGYSDEVLDVKFLGKNDSHIVVATNSSQLKVF--------ELLTNS-------CQILFG-HTDTVLTLDVFKKGFLFASCAKDRSVRVWQM-DSDSGQVCCVAQGTSHTNAVGSISCSRM-KASFVATGSQDCTVKVWDLPPDLSSEDICQLTPRTT-EKAHDKDVNSVAVSPNDKLLASGSQDRTARLWSLAVDGN-ISLLGVFRGHRRGIWSVCFSPVDQVLATSSADGTTKLWSLQDFSCLKTFEGHDASVLKCIFVSRGTQLLTSGSDGLVKLWTIKTNECVKTLDAHQDKVWGLHASRKDD----KMVTASADSNITVWADVTEAELAEEQAKQEDQILKQQELSNLLHEKKYLKALGLAISLDQPHTALTVIKAIRSGEDRCELLE-------------KTLLKLRVDQKESLLRFCVVWNTNARNCLDAQAVLQVLLTHMPPEELLQYQGARTHLEGLIPYTERHMQRIGRLLQASMFLNYM 793          

Query:   66 THFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNSLRKINQF-NKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIV---SDF--MNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENI--ETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYS-KQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDC-LAVLSLKGN-------QLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            T++ +  K   FY  GK      + +I    G  +N ++ ++ + ++   +   E++T F  + DD  ++ A + L+LK  D    S   + W + H  P+ +M  + SST L TGG D  +++W +     K +C    K     +++++ HP +  + + SS LD  I  WD  + + + V   H  SVT + F      M +S RD+   +W+         +P+ E++E  V++   +D   +     D++ +   G+ GI++    S    +   K  S   +   E  D + +  GL T    L     +  V    NI  Y    +  + +  G   +V D+  +GKN   I+V  ++  +++F               +L    CQ++ G H+  + ++ VF  G    S  KD  V +WQ+ DS   ++  +       + V S+   R  K  +V    +DC + V  L  +       QLT ++   K H   ++++ ++ N  LLA+GS+D+  +LWS       + + GV +GH+R I SV FS  +Q+L T+S D   KLW ++  +CL+ F+   A V + +F +   Q+++  SDG + +W   T +     D H  ++         D        AS+ S + ++ D TE  L + +  +E Q  ++QEL+NLL E K++ AL LAI L++P      + AI    ++                  K +  L + +  +L  F V W TN R CL  + V+ ++L  +   EL  +    T +     Y+++H +R      ++ F +Y+
Sbjct:   10 TNYAVSSKIEPFYKGGKVQISNDEQYIFCTCGSRVNILEISTGKIVHCVEHDDQEDITSFAVSSDDELLVTASRALLLKQWDWRRASC-TRSWRAIHTVPVASMTFDSSSTLLATGGCDGTIKLWDVV----KQYCTHNLKGSSGVVHLVQFHPDISRLQLFSSSLDCGIRMWDLRSSQCVCVLQSHYSSVTSLSFSADGGTMVSSGRDKICTVWDLNTRQAKRTVPIYEAVEGVVLLPKDADLSQLGVKSKDSHFI-TAGSKGILRVWHASTARCVYTQKAPSTLSSATGEAEDQDDNPFGL-THLFYLPASHRVATVTAEHNILLYQLPGLTTQQQFVGYSDEVLDVKFLGKNDSHIVVATNSSQLKVF---------------ELLTNSCQILFG-HTDTVLTLDVFKKGFLFASCAKDRSVRVWQM-DSDSGQVCCVAQGTSHTNAVGSISCSRM-KASFVATGSQDCTVKVWDLPPDLSSEDICQLTPRTT-EKAHDKDVNSVAVSPNDKLLASGSQDRTARLWSLAVDGN-ISLLGVFRGHRRGIWSVCFSPVDQVLATSSADGTTKLWSLQDFSCLKTFEGHDASVLKCIFVSRGTQLLTSGSDGLVKLWTIKTNECVKTLDAHQDKVWGLHASRKDD----KMVTASADSNITVWADVTEAELAEEQAKQEDQILKQQELSNLLHEKKYLKALGLAISLDQPHTALTVIKAIRSGEDRCELLE-------------KTLLKLRVDQKESLLRFCVVWNTNARNCLDAQAVLQVLLTHMPPEELLQYQGARTHLEGLIPYTERHMQRIGRLLQASMFLNYM 793          

Query:   72 FQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNSLRKINQF-NKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSK---INILRNHP-LLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIV---SDF--MNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENI--ETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYS-KQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDC-LAVLSLKGN-------QLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYL 2483
            + +  K   FY  GK      + +I    G  +N ++ ++ + ++   +   E++T F  + DD  ++ A + L+LK  D    S   + W + H  P+ +M  + SST L TGG D  +++W +     K +C    K     +++++ HP +  + + SS LD  I  WD  + + + V   H  SVT + F      M +S RD+   +W+         +P+ E++E  V++   +D   +     D++ +   G+ GI++    S    +   K  S   +   E  D + +  GL  +   L     +  V    NI  Y    +  + +  G   +V D+  +GKN   I+V  ++  +++F        E   +S       CQ++ G H+  + ++ VF  G    S  KD  V +WQ+ DS   ++  +       + V S+   R  K  +V    +DC + V  L  +       QLT ++   K H   ++++ ++ N  LLA+GS+D+  +LWS       + + GV +GH+R I SV FS  +Q+L T+S D   KLW ++  +CL+ F+   A V + +F +   Q+++  SDG + +W   T +     D H  ++         D        AS+ S + ++ D TE  L + +  +E Q  ++QEL+NLL E K++ AL LAI L++P      + AI    ++                  K +  L + +  +L  F V W TN R CL  + V+ ++L  +   EL  +    T +     Y+++H +R      ++ F +Y+
Sbjct:   16 YAVSSKIEPFYKGGKVQISNDEQYIFCTCGSRVNILEISTGKIVHCVEHDDQEDITSFAVSSDDELLVTASRALLLKQWDWRRASC-TRSWRAIHTVPVASMTFDSSSTLLATGGCDGTIKLWDVV----KQYCTHNLKGSSGVVHLVQFHPDISRLQLFSSSLDCGIRMWDLRSSQCVCVLQSHYSSVTSLSFSADGGTMVSSGRDKICTVWDLNTRQAKRTVPIYEAVEGVVLLPKDADLSQLGVKSKDSHFI-TAGSKGILRVWHASTARCVYTQKAPSTLSSATGEAEDQDDNPFGLTHL-FYLPASHRVATVTAEHNILLYQLPGLTTQQQFVGYSDEVLDVKFLGKNDSHIVVATNSSQLKVF--------ELLTNS-------CQILFG-HTDTVLTLDVFKKGFLFASCAKDRSVRVWQM-DSDSGQVCCVAQGTSHTNAVGSISCSRM-KASFVATGSQDCTVKVWDLPPDLSSEDICQLTPRTT-EKAHDKDVNSVAVSPNDKLLASGSQDRTARLWSLAVDGN-ISLLGVFRGHRRGIWSVCFSPVDQVLATSSADGTTKLWSLQDFSCLKTFEGHDASVLKCIFVSRGTQLLTSGSDGLVKLWTIKTNECVKTLDAHQDKVWGLHASRKDD----KMVTASADSNITVWADVTEAELAEEQAKQEDQILKQQELSNLLHEKKYLKALGLAISLDQPHTALTVIKAIRSGEDRCELLE-------------KTLLKLRVDQKESLLRFCVVWNTNARNCLDAQAVLQVLLTHMPPEELLQYQGARTHLEGLIPYTERHMQRIGRLLQASMFLNYM 797          

Query: 1428 SIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLW--SYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKL 2027
            S++ C+ + ++K     R   F + H + +++++ + +  ++A+ S+DK V+LW  S K  S E       + H   +  V FSD  Q L+TAS DK IK+W V     L  F      V  A F  +++ I+SC  D T+ +W++++ +    F  H G  +         G C   AAAS+ S + L+   T K L+  ++
Sbjct:   37 SVDSCVMIWNMKPQM--RAYRF-EGHKDAVTSVQFSPSGHMVASASRDKTVRLWVPSIKADSTEF------RAHTAAVRCVNFSDDGQTLVTASNDKTIKVWTVHRQKFLFSFNQHVNWVRCAKFSPDDRLIVSCSDDKTIKLWDKNSRECIQSFFEHAGYANHVDF--HPSGTC--IAAASTDSSVKLWDIRTNKMLQHYQV 226          

Query: 1497 KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQ-IISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITD 1928
            K H   +++++ + N   +ATGS D  V +W+ K + +        +GHK  ++SV+FS +  ++ +AS DK ++LW         +F++ TA  R + ++++ Q +++  +D T+ VW     K    F+ H   + C     D
Sbjct:   15 KGHRGAVTSVDFSCNMKQIATGSVDSCVMIWNMKPQMRAY----RFEGHKDAVTSVQFSPSGHMVASASRDKTVRLWVPSIKADSTEFRAHTAAVRCVNFSDDGQTLVTASNDKTIKVWTVHRQKFLFSFNQHVNWVRCAKFSPD 155          

Query: 1428 SIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLW--SYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLE 2015
            S++ C+ + ++K     R   F + H + +++++ + +  ++A+ S+DK V+LW  S K  S E       + H   +  V FSD  Q L+TAS DK IK+W V     L  F      V  A F  +++ I+SC  D T+ +W++++ +    F  H G  +         G C   AAAS+ S + L+   T K L+
Sbjct:   37 SVDSCVMIWNMKPQM--RAYRF-EGHKDAVTSVQFSPSGHMVASASRDKTVRLWVPSIKADSTEF------RAHTAAVRCVNFSDDGQTLVTASNDKTIKVWTVHRQKFLFSFNQHVNWVRCAKFSPDDRLIVSCSDDKTIKLWDKNSRECIQSFFEHAGYANHVDF--HPSGTC--IAAASTDSSVKLWDIRTNKMLQ 222          

Query: 1497 KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQ-IISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITD 1928
            K H   +++++ + N   +ATGS D  V +W+ K + +        +GHK  ++SV+FS +  ++ +AS DK ++LW         +F++ TA  R + ++++ Q +++  +D T+ VW     K    F+ H   + C     D
Sbjct:   15 KGHRGAVTSVDFSCNMKQIATGSVDSCVMIWNMKPQMRAY----RFEGHKDAVTSVQFSPSGHMVASASRDKTVRLWVPSIKADSTEFRAHTAAVRCVNFSDDGQTLVTASNDKTIKVWTVHRQKFLFSFNQHVNWVRCAKFSPD 155          

Query:   63 MTHFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYLGDAVTGFNIIDLTMDSS 2534
            MTHFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDI AWDTETGK LGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETE ENDSDKLSLWPCQLVHGGHSKDITSVSVFSD L IVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGN+L RKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYK+KSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLW VESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDT GNCRGFAAASSMSMM LYRDETEKNLEKSKLDREQQTQ+EQELNNLLFENKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYST+ICAFRSYSDQHYRRENEQTNSTGFNDYLGDAVTGFNIIDLTMDSS
Sbjct:    1 MTHFQLFDKFHSFYNAGKNICVTSDGFIISDDGESINYIDKNSLRKINQFNKTSEEMTCFVANPDDYTVIMADKNLMLKMVDRSNLSKHPKIWNSCHKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIAAWDTETGKLLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETELENDSDKLSLWPCQLVHGGHSKDITSVSVFSDRLHIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNKLNRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKSKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWSVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTGGNCRGFAAASSMSMMYLYRDETEKNLEKSKLDREQQTQQEQELNNLLFENKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTYICAFRSYSDQHYRRENEQTNSTGFNDYLGDAVTGFNIIDLTMDSS 824          

Query:  735 MESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETEYENDSDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSMSMMCLYRDETEKNLEKSKLDRXXXXXXXXXXXXXXXXXKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTFICAFRSYSDQHYRRENEQTNSTGFNDYLGDAVTGFNIIDLTMDSS 2534
            MESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETE ENDSDKLSLWPCQLVHGGHSKDITSVSVFSD L IVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGN+L RKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYK+KSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLW VESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDT GNCRGFAAASSMSMM LYRDETEKNLEKSKLDREQQTQ+EQELNNLLFENKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYST+ICAFRSYSDQHYRRENEQTNSTGFNDYLGDAVTGFNIIDLTMDSS
Sbjct:    1 MESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKSGLKTIRSILQTIDSLIFVRESDNIEFYSKQMQLEYELSGNLSDVKDIMIVGKNKDLILVVESAPYMRLFACKSFEETELENDSDKLSLWPCQLVHGGHSKDITSVSVFSDRLHIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNKLNRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKSKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWSVESLTCLQDFKSPTAVHRAMFYNNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTGGNCRGFAAASSMSMMYLYRDETEKNLEKSKLDREQQTQQEQELNNLLFENKFVHALRLAIKLNKPVLTYNTLNAINDNNEQPADEAIGAFELPDKTDMGKAVKSLDLTELRTLFSFAVKWMTNNRTCLIGEYVIGIMLGFIADAELTSWPEYSTYICAFRSYSDQHYRRENEQTNSTGFNDYLGDAVTGFNIIDLTMDSS 600          

Query: 1179 SDKLSLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDCLAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKT 1601
            +D+L LWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKL+LKLITS VVENDI+SSVCVDRKG+FIYVHYSIEDCLAVLSLKGN+LTRKS FSK HSNI+STMEMNINSSLL+TGSKDKN K+ S+ T
Sbjct:   21 TDELMLWPCQLVHGGHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLQLKLITSTVVENDIISSVCVDRKGEFIYVHYSIEDCLAVLSLKGNKLTRKSYFSKLHSNILSTMEMNINSSLLSTGSKDKNAKVNSHFT 161          

Query: 1221 GHSKDITSVSVFSDGLQIVSGGKDGKVSIWQVEDSAKLRLKLITSIVVENDIVSSVCVDRKGKFIYVHYSIEDC-LAVLSLKGNQLTRKSCFSKPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTA-VHRAMFYNNEKQIISCHSDGTMIVWN 1853
            GH   +T V    +  Q+ SGG D  + IW  +   +         V   D + SV     G+ +      +   L V S+KG  L  ++     H+  + +++++ ++  + TGS DK +K+W    K         L  HK  +  V+FS   QL+ ++S DK IKLW   +  C+  F+     V    F+ N   I S  +D  + +W+
Sbjct:   12 GHKDKVTCVDFNPNSSQLASGGIDSCLMIWNFKPQTR-----AYRFVGHEDAILSVKFSPTGQLVASASRDKTVRLWVPSIKGESLVFRA-----HTATVRSVDISCDNLEMVTGSDDKTIKVW----KMHRQKFSYSLNEHKNWVRCVRFSSDGQLIASSSDDKTIKLWDRHNQECIHTFQEHGGFVPSLAFHPNGSYIASGGTDSHVNIWD 210          

Query: 1497 KPHSNIISTMEMNINSSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCV----ESLTCLQDFKSPTAVHRAMFYN-NEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITD 1928
            K H + ++ ++ N NSS LA+G  D  + +W++K +++         GH+  I SVKFS T QL+ +AS DK ++LW      ESL     F++ TA  R++  + +  ++++   D T+ VW     K S   + H   + C    +D
Sbjct:   11 KGHKDKVTCVDFNPNSSQLASGGIDSCLMIWNFKPQTRAY----RFVGHEDAILSVKFSPTGQLVASASRDKTVRLWVPSIKGESLV----FRAHTATVRSVDISCDNLEMVTGSDDKTIKVWKMHRQKFSYSLNEHKNWVRCVRFSSD 151          

Query:  351 HKAPIFTMCLNKSSTRLTTGGADSKVRIWHIGQGEGKSFCCTYHKSKINILRNHPLLNMVVSSSMLDFDIVAWDTETGKQLGVFSGHQDSVTGIDFHELSNQMATSSRDETVIIWNCENFNKLILIPVMESLETCVIVSDFMNQPEADAYLVMVGGASGIIKTVSPSKRVIIQEFKKASLFENIETADINKDKS 932
            H   + ++  + + + + +GG DS V IW I   +      T H S +N +  HP  N ++SSS  D  +  +D   G+ L    GH+  + G  F       A+   D  V +W     +           E  + V    +QP+  A      G     K   P  R   QE ++  L  +     +N+D+S
Sbjct:  181 HGGFVPSLAFHPNGSYIASGGTDSHVNIWDIRMNKLLQHY-TSHTSPVNAVSFHPSGNFLISSSD-DSSMKIYDLLEGRLLYTVQGHEGPILGTAFSHCGEMFASGGADHQVFLWQAGQLS-----------EPGIAVHSGSSQPQHHA----TTGTKSTSKLTQPVVRR-TQELRRHDLNGD---RSVNQDQS 353          

Query: 1503 HSNIISTMEMNIN-SSLLATGSKDKNVKLWSYKTKSKELIIKGVLKGHKRCISSVKFSDTEQLLLTASLDKVIKLWCVESLTCLQDFKSPTAVHRAMFY---NNEKQIISCHSDGTMIVWNRDTGKDSSKFDIHDGQIDCFTLITDTDGNCRGFAAASSM 1970
            H N++ ++  N+  S  + TGS DK  K+WS    S    +    KGH   +  V+F+ +  L+ T  +D +  LW VES  C+ + +  TA   ++ +   +N K +I+   D T+I+W+   G+  S+   HD +I     + + DG    + A +SM
Sbjct:  133 HKNVVYSIAYNLPFSDKIVTGSFDKTAKMWSANDGS----LYHTFKGHTAEVVCVQFNPSSTLVGTGGMDTLAMLWDVESGKCVSNLQGHTAEVISLQFGQAHNGKHLITGSFDHTVILWDVHNGRRVSQLIGHDAEISA--AVFNFDGT---YVATASM 283