EF-hand domain-containing protein

Overview
NameEF-hand domain-containing protein
Smed IDSMED30005861
Length (bp)1410
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of EF-hand domain-containing protein (SMED30005861) t-SNE clustered cells

Violin plots show distribution of expression levels for EF-hand domain-containing protein (SMED30005861) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of EF-hand domain-containing protein (SMED30005861) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for EF-hand domain-containing protein (SMED30005861) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30005861

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30005861SMESG000001621.1 dd_Smed_v4_3909_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30005861SMESG000001621.1 dd_Smed_v4_3909_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30005861SMESG000001621.1 dd_Smed_v4_3909_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30005861SMESG000001621.1 dd_Smed_v4_3909_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005861SMESG000001621.1 Contig51242newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005861SMESG000001621.1 Contig51242uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Human
Match: RHBDL2 (rhomboid like 2 [Source:HGNC Symbol;Acc:HGNC:16083])

HSP 1 Score: 174.096 bits (440), Expect = 5.567e-50
Identity = 110/263 (41.83%), Postives = 154/263 (58.56%), Query Frame = 1 
Query:  382 EGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDR-FSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKN 1167
            E +  TY E  NC PPP  I +I+L+++ VFIYY +       +   +T  TG+ L SP IYSP +R EAWRFI YM +H G  H++ N  MQLVLG  LE+VHK  RV +VY+ GV+AGSLA S FD  +YLVGASGG YAL+G +F  V+ N+  M   +          G+FRL++++L+   D G A+Y R F  E  +P+ F+AHI G  AG  IG  V    +    +   FW+++  Y   ++ ++ FN+     N
Sbjct:   56 EKSRGTYLERANCFPPPVFIISISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAF----------GIFRLLIIILIIVLDMGFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYLACVLFAVFFNIFLSPAN 303
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Human
Match: RHBDL2 (rhomboid like 2 [Source:HGNC Symbol;Acc:HGNC:16083])

HSP 1 Score: 174.096 bits (440), Expect = 5.567e-50
Identity = 110/263 (41.83%), Postives = 154/263 (58.56%), Query Frame = 1 
Query:  382 EGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDR-FSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKN 1167
            E +  TY E  NC PPP  I +I+L+++ VFIYY +       +   +T  TG+ L SP IYSP +R EAWRFI YM +H G  H++ N  MQLVLG  LE+VHK  RV +VY+ GV+AGSLA S FD  +YLVGASGG YAL+G +F  V+ N+  M   +          G+FRL++++L+   D G A+Y R F  E  +P+ F+AHI G  AG  IG  V    +    +   FW+++  Y   ++ ++ FN+     N
Sbjct:   56 EKSRGTYLERANCFPPPVFIISISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAF----------GIFRLLIIILIIVLDMGFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYLACVLFAVFFNIFLSPAN 303
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Human
Match: RHBDL3 (rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502])

HSP 1 Score: 167.548 bits (423), Expect = 1.956e-46
Identity = 116/388 (29.90%), Postives = 193/388 (49.74%), Query Frame = 1 
Query:   70 ENNFRPLFDQKEV--TGGIPLVELRTSL--RESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPI---GFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVIC 1155
            E++++ LFDQ +   TG I   + R+ L    SKL P+K    L  AD   +  I Y++F   ++ + S +  +                   L+L +R+IR+      P  I R                K Y ++Y C PPP+ +  +TL ++  F+Y  + L     +          +L++ L+Y P  R + WR++ Y+F+H G  HL  N ++QL++G  LE+VH   R+ +VY+ GV+AGSLA S  D T  +VG+SGG YAL+ AH A +V NW  M+ Q+           + R+ V L+    + G A++ RF      P     F AH+GG   G  +G+ VLRN E +  ++  +W+ + +Y +F++ ++ +N+  
Sbjct:   36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDR----------------KWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPR-----YLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQF----------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFA 392
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Human
Match: RHBDL3 (rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502])

HSP 1 Score: 162.155 bits (409), Expect = 1.526e-44
Identity = 111/373 (29.76%), Postives = 183/373 (49.06%), Query Frame = 1 
Query:  109 TGGIPLVELRTSL--RESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPI---GFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVIC 1155
            TG I   + R+ L    SKL P+K    L  AD   +  I Y++F   ++ + S +  +                   L+L +R+IR+      P  I R                K Y ++Y C PPP+ +  +TL ++  F+Y  + L     +          +L++ L+Y P  R + WR++ Y+F+H G  HL  N ++QL++G  LE+VH   R+ +VY+ GV+AGSLA S  D T  +VG+SGG YAL+ AH A +V NW  M+ Q+           + R+ V L+    + G A++ RF      P     F AH+GG   G  +G+ VLRN E +  ++  +W+ + +Y +F++ ++ +N+  
Sbjct:   43 TGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDR----------------KWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPR-----YLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQF----------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFA 384
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Human
Match: RHBDL1 (rhomboid like 1 [Source:HGNC Symbol;Acc:HGNC:10007])

HSP 1 Score: 153.68 bits (387), Expect = 1.424e-41
Identity = 107/356 (30.06%), Postives = 172/356 (48.31%), Query Frame = 1 
Query:  148 RESKLPPNKVNRFLNNADKDQNSLITYEEFYD-------------------QLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTP---IGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
             E  L P K++  +  A  ++   + Y+E  D                    L R+       L + KR +R     + P  + R                + Y   +   PPP  + ++TL+QI VF+ Y  +LN    +T         +++SPL+Y P  R  AWRF+ YMF+H G   L FN ++QL++G  LE+VH   R++++Y+ GVLAGSL  S  D    +VG SGG YAL  AH A VV NW  M+  +           + R+++ L+    + G A++ RFS  +P       F AH+ GA+ G  +G+ +LR+ E +  ++  +WV L+ Y  F++ ++ +NV
Sbjct:   35 HELPLDPAKLDMLVALAQSNEQGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPCEVDR----------------RWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPE-----YMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPY----------KLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNV 359
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Celegans
Match: rom-1 (Rhomboid-related protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q19821])

HSP 1 Score: 152.91 bits (385), Expect = 5.588e-42
Identity = 124/379 (32.72%), Postives = 179/379 (47.23%), Query Frame = 1 
Query:   64 EIENNFRPLFDQKEVTGG---IPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRT--NDVTARTGVHLRSP---LIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICD--SKNL 1170
            +    +R  F+Q   TG    IP+  L + +   K+P       L N       +   +E  D+L   D    +K+   K   R+ ++ +  D    + +D Q         V +Y ++Y+  PPP  +  IT+ Q+G+F +Y     +D  R+   D       H  +     I++P  R EAWRF  YMFLH G  HL+ N I+QL++G  LE+ HK WR+  +Y+L V +GSL     D    LVGAS G YALI AH A V+ NW  M  +W+            R++VL +    D G AI+ RF       +   AHI GA+ G   G  VL N+     EKI  +V L LY  F   +IIF ++    SKNL
Sbjct:    7 KFRKTYRHQFNQLR-TGDETEIPMSTLASRIETRKIP-------LTNGQ-----IHAIKEAPDELVDIDG--FQKIVTSKAAQRSTIKRIMYDMADPIMSDSQKI------EVHSYIDSYSWCPPPIFMLLITIIQVGIFFFY---WESDGGRSIWTDCAGCFVHHNHTAPGIFIFAPKLRGEAWRFTSYMFLHAGLNHLLGNVIIQLLVGIPLEVAHKIWRIGPIYLLAVTSGSLLQYAIDPNSLLVGASAGVYALIFAHVANVILNWHEMPLRWI------------RVLVLFVFIFLDFGGAIHRRFYTNDCDSVSHLAHIAGAVTGLFFGYVVLYNVVEHRIEKIIRYVCLFLYSAFFATTIIFVIVRQPYSKNL 349
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Celegans
Match: rom-2 (Rhomboid-related protein 2 [Source:UniProtKB/Swiss-Prot;Acc:P34356])

HSP 1 Score: 125.561 bits (314), Expect = 2.511e-31
Identity = 78/240 (32.50%), Postives = 123/240 (51.25%), Query Frame = 1 
Query:  406 EAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFM 1125
            + Y C PPP  +  +++ Q+  ++YYV+      D +  V     +   SPLI S Y   E WR   Y  ++ G  H+IFN ++QL +G  LE+VH+ WR+ I+Y +GVL GS+     D T +L G + G ++LI +H  T+ TN+  M+            +   RL +L++ A  D  +A+Y RF       +    H+GG +AG L    + R  +   +  + FWVSLVL   F+
Sbjct:  114 QRYKCVPPPIFLIFLSIVQLAFYLYYVV------DSSEGVWLSGPIPTMSPLIVSQYHLPELWRLFTYCLINVGIFHIIFNILIQLAIGVPLELVHR-WRIYILYFMGVLFGSILSLALDPTVFLCGGAAGSFSLIASHITTIATNFKEME------------NATCRLPILIVFAALDYVLAVYQRFFAPRIDKVSMYGHLGGLVAGILFTFILFRGSKPSRFYTVSFWVSLVLSGFFI 334
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Fly
Match: rho-4 (gene:FBgn0030318 transcript:FBtr0073519)

HSP 1 Score: 186.037 bits (471), Expect = 1.443e-53
Identity = 121/370 (32.70%), Postives = 192/370 (51.89%), Query Frame = 1 
Query:   40 RKSQKIIDEIENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            RK  +I D+ +++   L +  E      L EL +      +P    ++ L  +D+D +  + +EEFY    R       K  +R  + R    +V P +   +  D+ D           Y +  +  PPP  +   ++ +I +F+  VI    D +  + +   T     +  IY+PY+R E WRF+ YMF+H G +HL+ N I+Q+ LG  LE+VH +WRV +VY+ GVLAGS+  S      +L GASGG YALI AH AT++ N+  M+              + +L+  L+    D G ++Y   + +    IG+ AH+ GA+AG L+GI VLRNLEV+ WE+I +WV++++Y   M   II +V
Sbjct:   72 RKMHEIFDKHDSDRDGLINTHE------LKELISDGYCRDIPAYIADQILKRSDQDNDGHLDFEEFYAMSLRH------KWMVRNMLTRYCRYVVPPPK--PLEGDEPD---------GAYEKQMSICPPPLTMVLFSIIEIIMFLVDVIHFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEMEY------------AIVQLLAFLVFCFTDLGTSVYRHLTDQ-HDQIGYVAHLSGAVAGLLVGIGVLRNLEVRRWERILWWVAVIVYFALMTTGIIIHV 405
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Fly
Match: rho-4 (gene:FBgn0030318 transcript:FBtr0073518)

HSP 1 Score: 186.037 bits (471), Expect = 1.443e-53
Identity = 121/370 (32.70%), Postives = 192/370 (51.89%), Query Frame = 1 
Query:   40 RKSQKIIDEIENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            RK  +I D+ +++   L +  E      L EL +      +P    ++ L  +D+D +  + +EEFY    R       K  +R  + R    +V P +   +  D+ D           Y +  +  PPP  +   ++ +I +F+  VI    D +  + +   T     +  IY+PY+R E WRF+ YMF+H G +HL+ N I+Q+ LG  LE+VH +WRV +VY+ GVLAGS+  S      +L GASGG YALI AH AT++ N+  M+              + +L+  L+    D G ++Y   + +    IG+ AH+ GA+AG L+GI VLRNLEV+ WE+I +WV++++Y   M   II +V
Sbjct:   72 RKMHEIFDKHDSDRDGLINTHE------LKELISDGYCRDIPAYIADQILKRSDQDNDGHLDFEEFYAMSLRH------KWMVRNMLTRYCRYVVPPPK--PLEGDEPD---------GAYEKQMSICPPPLTMVLFSIIEIIMFLVDVIHFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEMEY------------AIVQLLAFLVFCFTDLGTSVYRHLTDQ-HDQIGYVAHLSGAVAGLLVGIGVLRNLEVRRWERILWWVAVIVYFALMTTGIIIHV 405
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Fly
Match: stet (gene:FBgn0020248 transcript:FBtr0072712)

HSP 1 Score: 167.933 bits (424), Expect = 2.882e-46
Identity = 128/396 (32.32%), Postives = 200/396 (50.51%), Query Frame = 1 
Query:   67 IENNFRPLFD--QKEVTGGIPLVELRTSLRE----SKLPPNKVNRFLNNADKDQ----NSLITYEEFYDQLTREDSRTLEKLALRKR----IIRNAVRIV---APDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFS-----------------KEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVI 1152
            + + ++ LFD    E  G I + E   +L+     S++P NK    L  A K +       +T+++F + ++ + +R+  K A+  R       N  ++V    P   + V+A   +     E   K Y++ Y C PPPF I  +TL ++G F+Y+ +        T +   R  +   S  IY P +R E WRF+ YM LH G++HL FN  +QLV G  LE+VH   R+A +Y  GVLAGSL  S FD   +LVGASGG YAL+ AH A V+ N+  M+             GV +L+ +L+    D G AIY R++                  E    + + AH+ GA+AG  IG+ VL++ E K  E++ +W++L  Y   ++ +I FN++
Sbjct:   86 LRDKWKLLFDMFDPEGFGEISVEEFLEALKSPEFLSQVPMNKRELLLERAKKAKLPTGPGYVTFQDFVNVMSGKRTRSF-KCAVHHRDREVCSENDFQLVLNEPPLFRKMVHAVAMEILP-EERDRKYYADRYTCCPPPFFIILVTLVELGFFVYHSVV-------TGEAAPRGPIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLLNYHQMRY------------GVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSFEQKLHEQLLWWIALGTYLALVVFAIAFNIM 460
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Fly
Match: stet (gene:FBgn0020248 transcript:FBtr0072713)

HSP 1 Score: 160.999 bits (406), Expect = 4.241e-45
Identity = 101/270 (37.41%), Postives = 147/270 (54.44%), Query Frame = 1 
Query:  394 KTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFS-----------------KEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVI 1152
            K Y++ Y C PPPF I  +TL ++G F+Y+ +        T +   R  +   S  IY P +R E WRF+ YM LH G++HL FN  +QLV G  LE+VH   R+A +Y  GVLAGSL  S FD   +LVGASGG YAL+ AH A V+ N+  M+             GV +L+ +L+    D G AIY R++                  E    + + AH+ GA+AG  IG+ VL++ E K  E++ +W++L  Y   ++ +I FN++
Sbjct:   55 KYYADRYTCCPPPFFIILVTLVELGFFVYHSVV-------TGEAAPRGPIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLLNYHQMRY------------GVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSFEQKLHEQLLWWIALGTYLALVVFAIAFNIM 305
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Fly
Match: rho (gene:FBgn0004635 transcript:FBtr0072694)

HSP 1 Score: 136.346 bits (342), Expect = 9.555e-36
Identity = 89/249 (35.74%), Postives = 136/249 (54.62%), Query Frame = 1 
Query:  430 PFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSP----LIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF---SKEVPTP-IGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVI 1152
            P+ I  I++ +I +F Y         DR        G+ +  P    L+Y P RR++ WRF  YMFLH  + HL FN ++QL  G  LE++H   R+ ++Y+ GV AGSL  S  DS  +LVGASGG YAL+ AH A +  N+  M+            S   +L  +++    D G A+Y ++   S     P + + AH+ GALAG  IG  VL+N   + +E++ +W++L +YC F + +I+FN+I
Sbjct:  102 PWFILVISIIEIAIFAY---------DRYTMPAQNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFLVGASGGVYALLAAHLANITLNYAHMK------------SASTQLGSVVIFVSCDLGYALYTQYFDGSAFAKGPQVSYIAHLTGALAGLTIGFLVLKNFGHREYEQLIWWLALGVYCAFTVFAIVFNLI 329
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 178.333 bits (451), Expect = 5.058e-52
Identity = 112/275 (40.73%), Postives = 161/275 (58.55%), Query Frame = 1 
Query:  334 RIQRVNADQQDYCNW--GEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF-SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            R++RV    ++   W   E   +TY E  NC PPP  I  I+L+++ VFIYY +       +   +T  TG+   SPL Y P +R EAWRF+ YMF+H G  H++ N +MQL+LG  LE+VHK + V +VY+ GVLAGSLA S FD    LVGASGG YAL+G +F   + N+  M+          +  GVFR+++++L+ G D G A+Y RF   E    + F AHIGG +AG  IG     N   +  +   FW+ +V Y +F++ ++IFN+
Sbjct:   27 RVRRVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR----------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNI 286
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 178.333 bits (451), Expect = 5.058e-52
Identity = 112/275 (40.73%), Postives = 161/275 (58.55%), Query Frame = 1 
Query:  334 RIQRVNADQQDYCNW--GEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF-SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            R++RV    ++   W   E   +TY E  NC PPP  I  I+L+++ VFIYY +       +   +T  TG+   SPL Y P +R EAWRF+ YMF+H G  H++ N +MQL+LG  LE+VHK + V +VY+ GVLAGSLA S FD    LVGASGG YAL+G +F   + N+  M+          +  GVFR+++++L+ G D G A+Y RF   E    + F AHIGG +AG  IG     N   +  +   FW+ +V Y +F++ ++IFN+
Sbjct:   27 RVRRVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR----------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNI 286
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 178.333 bits (451), Expect = 5.058e-52
Identity = 112/275 (40.73%), Postives = 161/275 (58.55%), Query Frame = 1 
Query:  334 RIQRVNADQQDYCNW--GEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF-SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            R++RV    ++   W   E   +TY E  NC PPP  I  I+L+++ VFIYY +       +   +T  TG+   SPL Y P +R EAWRF+ YMF+H G  H++ N +MQL+LG  LE+VHK + V +VY+ GVLAGSLA S FD    LVGASGG YAL+G +F   + N+  M+          +  GVFR+++++L+ G D G A+Y RF   E    + F AHIGG +AG  IG     N   +  +   FW+ +V Y +F++ ++IFN+
Sbjct:   27 RVRRVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR----------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNI 286
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 178.333 bits (451), Expect = 5.058e-52
Identity = 112/275 (40.73%), Postives = 161/275 (58.55%), Query Frame = 1 
Query:  334 RIQRVNADQQDYCNW--GEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF-SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            R++RV    ++   W   E   +TY E  NC PPP  I  I+L+++ VFIYY +       +   +T  TG+   SPL Y P +R EAWRF+ YMF+H G  H++ N +MQL+LG  LE+VHK + V +VY+ GVLAGSLA S FD    LVGASGG YAL+G +F   + N+  M+          +  GVFR+++++L+ G D G A+Y RF   E    + F AHIGG +AG  IG     N   +  +   FW+ +V Y +F++ ++IFN+
Sbjct:   27 RVRRVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR----------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNI 286
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 178.333 bits (451), Expect = 5.058e-52
Identity = 112/275 (40.73%), Postives = 161/275 (58.55%), Query Frame = 1 
Query:  334 RIQRVNADQQDYCNW--GEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF-SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            R++RV    ++   W   E   +TY E  NC PPP  I  I+L+++ VFIYY +       +   +T  TG+   SPL Y P +R EAWRF+ YMF+H G  H++ N +MQL+LG  LE+VHK + V +VY+ GVLAGSLA S FD    LVGASGG YAL+G +F   + N+  M+          +  GVFR+++++L+ G D G A+Y RF   E    + F AHIGG +AG  IG     N   +  +   FW+ +V Y +F++ ++IFN+
Sbjct:   27 RVRRVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR----------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNI 286
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Xenopus
Match: eif4a1 (eukaryotic translation initiation factor 4A1 [Source:Xenbase;Acc:XB-GENE-491256])

HSP 1 Score: 172.555 bits (436), Expect = 1.374e-49
Identity = 104/252 (41.27%), Postives = 147/252 (58.33%), Query Frame = 1 
Query:  397 TYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF-SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            TY E  NC PPP  I +++++++ VFIYY + +     +   +T  TGV   SP IY P +R EAWRFI YM +H G  H+I N  +QL+LG  LE+VHK  R+ +VY+ GV+ GSLA S FDS   LVGASGG YALIG +F  V+ N+  M   +          G+FR++V++ + G D G A+Y R+ S E    + F AH  G LAG  IG  V    +    +   FW+ +  Y  F+I +++FN+
Sbjct:   48 TYLERANCLPPPIFIISVSIAELAVFIYYAVWM----PQKQWITLDTGV-WNSPFIYRPDKREEAWRFISYMMVHAGMTHIIGNLALQLLLGIPLELVHKGHRIGLVYLAGVIGGSLASSVFDSGLALVGASGGVYALIGGYFMNVLVNFKDMIPLF----------GIFRILVIITIVGTDVGFALYRRYISHETGQKVSFVAHFAGGLAGMSIGYTVFSCFDKNLIKDPRFWICIAAYAAFVIFAVLFNI 284
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Xenopus
Match: rhbdf2 (rhomboid 5 homolog 2 [Source:NCBI gene;Acc:100036646])

HSP 1 Score: 55.4546 bits (132), Expect = 1.449e-7
Identity = 26/86 (30.23%), Postives = 46/86 (53.49%), Query Frame = 1 
Query:  610 MFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQW 867
            +FLH G IH   + + Q+ +   LE +  + R++I+YIL  + G+LA + F   +  VG +G  + L+   F  +  +W  + K W
Sbjct:  596 LFLHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLASALFLPYRAEVGPAGSQFGLLACLFVELFQSWQILAKPW 681
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Xenopus
Match: rhbdf2 (rhomboid 5 homolog 2 [Source:NCBI gene;Acc:100036646])

HSP 1 Score: 55.4546 bits (132), Expect = 1.455e-7
Identity = 26/86 (30.23%), Postives = 46/86 (53.49%), Query Frame = 1 
Query:  610 MFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQW 867
            +FLH G IH   + + Q+ +   LE +  + R++I+YIL  + G+LA + F   +  VG +G  + L+   F  +  +W  + K W
Sbjct:  586 LFLHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLASALFLPYRAEVGPAGSQFGLLACLFVELFQSWQILAKPW 671
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Xenopus
Match: rhbdf2 (rhomboid 5 homolog 2 [Source:NCBI gene;Acc:100036646])

HSP 1 Score: 55.4546 bits (132), Expect = 1.458e-7
Identity = 26/86 (30.23%), Postives = 46/86 (53.49%), Query Frame = 1 
Query:  610 MFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQW 867
            +FLH G IH   + + Q+ +   LE +  + R++I+YIL  + G+LA + F   +  VG +G  + L+   F  +  +W  + K W
Sbjct:  631 LFLHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLASALFLPYRAEVGPAGSQFGLLACLFVELFQSWQILAKPW 716
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Xenopus
Match: rhbdf2 (rhomboid 5 homolog 2 [Source:NCBI gene;Acc:100036646])

HSP 1 Score: 55.4546 bits (132), Expect = 1.510e-7
Identity = 26/86 (30.23%), Postives = 46/86 (53.49%), Query Frame = 1 
Query:  610 MFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQW 867
            +FLH G IH   + + Q+ +   LE +  + R++I+YIL  + G+LA + F   +  VG +G  + L+   F  +  +W  + K W
Sbjct:  633 LFLHAGVIHCCVSVVFQMTVLRDLEKLAGWLRISIIYILSGITGNLASALFLPYRAEVGPAGSQFGLLACLFVELFQSWQILAKPW 718
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Mouse
Match: Rhbdl2 (rhomboid like 2 [Source:MGI Symbol;Acc:MGI:3608413])

HSP 1 Score: 179.489 bits (454), Expect = 2.858e-52
Identity = 110/265 (41.51%), Postives = 152/265 (57.36%), Query Frame = 1 
Query:  382 EGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVP---TPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKN 1167
            E   +TY E  NC PPP  I  I+L+++ VFIYY +       +   +T  TG+ L SPL Y P +R EAWRFI YM +H G  H++ N +MQ+VLG  LE+VHK  RV +VY+ GVLAGSLA S FD  K LVGASGG YAL+G +F  V+ N+  M   +          G+ RL+V++L+   D G A+Y RF   VP   +P+ F+AHI G  AG  IG  V    +    +   FW+++  Y   ++ ++ FN+     N
Sbjct:   55 EPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPAF----------GIVRLLVIILIVASDMGFALYRRFF--VPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIFLSPAN 302
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Mouse
Match: Rhbdl2 (rhomboid like 2 [Source:MGI Symbol;Acc:MGI:3608413])

HSP 1 Score: 179.489 bits (454), Expect = 2.858e-52
Identity = 110/265 (41.51%), Postives = 152/265 (57.36%), Query Frame = 1 
Query:  382 EGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVP---TPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKN 1167
            E   +TY E  NC PPP  I  I+L+++ VFIYY +       +   +T  TG+ L SPL Y P +R EAWRFI YM +H G  H++ N +MQ+VLG  LE+VHK  RV +VY+ GVLAGSLA S FD  K LVGASGG YAL+G +F  V+ N+  M   +          G+ RL+V++L+   D G A+Y RF   VP   +P+ F+AHI G  AG  IG  V    +    +   FW+++  Y   ++ ++ FN+     N
Sbjct:   55 EPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPAF----------GIVRLLVIILIVASDMGFALYRRFF--VPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIFLSPAN 302
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Mouse
Match: Rhbdl3 (rhomboid like 3 [Source:MGI Symbol;Acc:MGI:2179276])

HSP 1 Score: 165.622 bits (418), Expect = 6.128e-46
Identity = 118/386 (30.57%), Postives = 196/386 (50.78%), Query Frame = 1 
Query:   70 ENNFRPLFDQKE--VTGGIPLVELRTSL--RESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPI---GFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            E++++ LF++ +   TG I   + R+ L    SKL P+K    L  AD   +  I Y++F + ++ + S +  +                   L+L +R+IR+      P  I R                K Y ++Y C PPP+ +  ITL ++ +F+Y  + L   D     VT     +L++ L+Y P  R +AWR++ Y+F+H G   L  N  +QL++G  LE+VH   R+ +VY+ GV+AGSLA S  D T  +VG+SGG YAL+ AH A +V NW  M+ Q+           + R+ V L+    + G A++ RF      P     F AH+GG   G  +G+ VLRN E +  ++  +W+ + +Y +F++ ++ +N+
Sbjct:   36 EDHWKVLFEKFDPGSTGYISTGKFRSLLESHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDR----------------KWYYDSYTCCPPPWFMITITLLEVALFLYNGVLL---DQFVLQVTHPR--YLKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQF----------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVTMYTIFVLFAVFWNI 390
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Mouse
Match: Rhbdl1 (rhomboid like 1 [Source:MGI Symbol;Acc:MGI:2384891])

HSP 1 Score: 152.91 bits (385), Expect = 1.489e-41
Identity = 108/356 (30.34%), Postives = 173/356 (48.60%), Query Frame = 1 
Query:  148 RESKLPPNKVNRFLNNADKDQNSLITYEEFYD-------------------QLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTP---IGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
             E  L P K++  +  A  ++   + Y+E  D                    L R+       L++ KR +R     + P  + R                + Y   +   PPP  + ++TL+QI VF+ Y  +LN    +T         +++SPL+Y P  R  AWRF+ YMF+H G   L FN ++QL++G  LE+VH   R++++Y+ GVLAGSL  S  D    +VG SGG YAL  AH A VV NW  M+  +           + R+++ L+    + G A++ RFS  +P       F AH+ GA+ G  +G+ +LR+ E +  ++  +WV L+ Y  F++ +I +NV
Sbjct:   35 HELPLDPTKLDMLVALAQSNERGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDEPGLSVYKRFVRYVAYEILPCEVDR----------------RWYFYRHRTCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPE-----YMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPY----------KLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNV 359
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Mouse
Match: Rhbdl1 (rhomboid like 1 [Source:MGI Symbol;Acc:MGI:2384891])

HSP 1 Score: 140.198 bits (352), Expect = 6.339e-37
Identity = 104/360 (28.89%), Postives = 169/360 (46.94%), Query Frame = 1 
Query:  148 RESKLPPNKVNRFLNNADKDQNSLITYEEFYD-----------------------QLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTP---IGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
             E  L P K++  +  A  ++   + Y+E  D                        L R+       L++ KR +R     + P  + R                + Y   +   PPP  + ++TL+QI VF+ Y  +LN    +T         +++SPL+Y P  R  AWRF+ YMF+H G   L FN ++QL++G  LE+VH   R++++Y+ GVLA        D    +VG SGG YAL  AH A VV NW  M+  +           + R+++ L+    + G A++ RFS  +P       F AH+ GA+ G  +G+ +LR+ E +  ++  +WV L+ Y  F++ +I +NV
Sbjct:   35 HELPLDPTKLDMLVALAQSNERGQVCYQELVDLVSAMISSKRSSSFKRAIANGQRALPRDGLLDEPGLSVYKRFVRYVAYEILPCEVDR----------------RWYFYRHRTCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPE-----YMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLA--------DMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPY----------KLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNV 355
[Close]
BLAST of EF-hand domain-containing protein vs. UniProt/SwissProt
Match: sp|A2AGA4|RHBL2_MOUSE (Rhomboid-related protein 2 OS=Mus musculus OX=10090 GN=Rhbdl2 PE=1 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 1.999e-51
Identity = 110/265 (41.51%), Postives = 152/265 (57.36%), Query Frame = 1 
Query:  382 EGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVP---TPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKN 1167
            E   +TY E  NC PPP  I  I+L+++ VFIYY +       +   +T  TG+ L SPL Y P +R EAWRFI YM +H G  H++ N +MQ+VLG  LE+VHK  RV +VY+ GVLAGSLA S FD  K LVGASGG YAL+G +F  V+ N+  M   +          G+ RL+V++L+   D G A+Y RF   VP   +P+ F+AHI G  AG  IG  V    +    +   FW+++  Y   ++ ++ FN+     N
Sbjct:   55 EPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREMIPAF----------GIVRLLVIILIVASDMGFALYRRFF--VPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIFLSPAN 302
[Close]
BLAST of EF-hand domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NX52|RHBL2_HUMAN (Rhomboid-related protein 2 OS=Homo sapiens OX=9606 GN=RHBDL2 PE=1 SV=2)

HSP 1 Score: 174.096 bits (440), Expect = 2.673e-49
Identity = 110/263 (41.83%), Postives = 154/263 (58.56%), Query Frame = 1 
Query:  382 EGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDR-FSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKN 1167
            E +  TY E  NC PPP  I +I+L+++ VFIYY +       +   +T  TG+ L SP IYSP +R EAWRFI YM +H G  H++ N  MQLVLG  LE+VHK  RV +VY+ GV+AGSLA S FD  +YLVGASGG YAL+G +F  V+ N+  M   +          G+FRL++++L+   D G A+Y R F  E  +P+ F+AHI G  AG  IG  V    +    +   FW+++  Y   ++ ++ FN+     N
Sbjct:   56 EKSRGTYLERANCFPPPVFIISISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAF----------GIFRLLIIILIIVLDMGFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYLACVLFAVFFNIFLSPAN 303
[Close]
BLAST of EF-hand domain-containing protein vs. UniProt/SwissProt
Match: sp|P58872|RHBL3_HUMAN (Rhomboid-related protein 3 OS=Homo sapiens OX=9606 GN=RHBDL3 PE=2 SV=1)

HSP 1 Score: 167.548 bits (423), Expect = 9.395e-46
Identity = 116/388 (29.90%), Postives = 193/388 (49.74%), Query Frame = 1 
Query:   70 ENNFRPLFDQKEV--TGGIPLVELRTSL--RESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPI---GFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVIC 1155
            E++++ LFDQ +   TG I   + R+ L    SKL P+K    L  AD   +  I Y++F   ++ + S +  +                   L+L +R+IR+      P  I R                K Y ++Y C PPP+ +  +TL ++  F+Y  + L     +          +L++ L+Y P  R + WR++ Y+F+H G  HL  N ++QL++G  LE+VH   R+ +VY+ GV+AGSLA S  D T  +VG+SGG YAL+ AH A +V NW  M+ Q+           + R+ V L+    + G A++ RF      P     F AH+GG   G  +G+ VLRN E +  ++  +W+ + +Y +F++ ++ +N+  
Sbjct:   36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDR----------------KWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPR-----YLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQF----------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFA 392
[Close]
BLAST of EF-hand domain-containing protein vs. UniProt/SwissProt
Match: sp|P58873|RHBL3_MOUSE (Rhomboid-related protein 3 OS=Mus musculus OX=10090 GN=Rhbdl3 PE=2 SV=1)

HSP 1 Score: 165.622 bits (418), Expect = 4.287e-45
Identity = 118/386 (30.57%), Postives = 196/386 (50.78%), Query Frame = 1 
Query:   70 ENNFRPLFDQKE--VTGGIPLVELRTSL--RESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPI---GFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            E++++ LF++ +   TG I   + R+ L    SKL P+K    L  AD   +  I Y++F + ++ + S +  +                   L+L +R+IR+      P  I R                K Y ++Y C PPP+ +  ITL ++ +F+Y  + L   D     VT     +L++ L+Y P  R +AWR++ Y+F+H G   L  N  +QL++G  LE+VH   R+ +VY+ GV+AGSLA S  D T  +VG+SGG YAL+ AH A +V NW  M+ Q+           + R+ V L+    + G A++ RF      P     F AH+GG   G  +G+ VLRN E +  ++  +W+ + +Y +F++ ++ +N+
Sbjct:   36 EDHWKVLFEKFDPGSTGYISTGKFRSLLESHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDR----------------KWYYDSYTCCPPPWFMITITLLEVALFLYNGVLL---DQFVLQVTHPR--YLKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQF----------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVTMYTIFVLFAVFWNI 390
[Close]
BLAST of EF-hand domain-containing protein vs. UniProt/SwissProt
Match: sp|Q19821|RHOM1_CAEEL (Rhomboid-related protein 1 OS=Caenorhabditis elegans OX=6239 GN=rom-1 PE=2 SV=2)

HSP 1 Score: 152.91 bits (385), Expect = 7.108e-41
Identity = 124/379 (32.72%), Postives = 179/379 (47.23%), Query Frame = 1 
Query:   64 EIENNFRPLFDQKEVTGG---IPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRT--NDVTARTGVHLRSP---LIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICD--SKNL 1170
            +    +R  F+Q   TG    IP+  L + +   K+P       L N       +   +E  D+L   D    +K+   K   R+ ++ +  D    + +D Q         V +Y ++Y+  PPP  +  IT+ Q+G+F +Y     +D  R+   D       H  +     I++P  R EAWRF  YMFLH G  HL+ N I+QL++G  LE+ HK WR+  +Y+L V +GSL     D    LVGAS G YALI AH A V+ NW  M  +W+            R++VL +    D G AI+ RF       +   AHI GA+ G   G  VL N+     EKI  +V L LY  F   +IIF ++    SKNL
Sbjct:    7 KFRKTYRHQFNQLR-TGDETEIPMSTLASRIETRKIP-------LTNGQ-----IHAIKEAPDELVDIDG--FQKIVTSKAAQRSTIKRIMYDMADPIMSDSQKI------EVHSYIDSYSWCPPPIFMLLITIIQVGIFFFY---WESDGGRSIWTDCAGCFVHHNHTAPGIFIFAPKLRGEAWRFTSYMFLHAGLNHLLGNVIIQLLVGIPLEVAHKIWRIGPIYLLAVTSGSLLQYAIDPNSLLVGASAGVYALIFAHVANVILNWHEMPLRWI------------RVLVLFVFIFLDFGGAIHRRFYTNDCDSVSHLAHIAGAVTGLFFGYVVLYNVVEHRIEKIIRYVCLFLYSAFFATTIIFVIVRQPYSKNL 349
[Close]
BLAST of EF-hand domain-containing protein vs. TrEMBL
Match: A0A564YNU8 (EF-hand domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS8134 PE=3 SV=1)

HSP 1 Score: 421.394 bits (1082), Expect = 8.674e-142
Identity = 203/393 (51.65%), Postives = 274/393 (69.72%), Query Frame = 1 
Query:   37 SRKSQKIIDEIENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPD--------RIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKNLCYATNFN 1191
            +R  ++  + ++ NF+P F+  E  GG+PL  L+  L +S +PP +  RF   AD +++  + Y+EF  Q+  EDS+ L KLA  KR +  AV  VAP         ++QR   D+ D  NWGE  V  Y EAY+C+PPP  IP IT SQI VF+YY I L+ DD+  NDVTA +GV ++SPLIY P +R +AWRF+ YMF+H GY HLIFNCI+Q  LGT LE+VHKFWRV IVY+LGVLAGSLAHS  D    L GASGGCYALIGAH AT++TNW TMQ  WL++P+NFLSSG  RL ++LL+AG DTG AIY+RF+    + +GF++H+GG  AG L+G+PVLRNLE++ WEK+CFW+ + L+ +FM  +++FN  C+ +  C  T+++
Sbjct:    5 TRGEREFREHLDVNFKPPFEAYEREGGMPLGVLQRLLHDSGIPPARTKRFFRKADLNRDERVNYDEFLRQIMFEDSQFLHKLAFGKRALNRAVIAVAPQMARRKQRIQMQRNGIDETDLYNWGEENVNNYIEAYDCRPPPIFIPLITFSQIAVFVYYAIVLSQDDNPFNDVTATSGVPMKSPLIYLPTKRYQAWRFVSYMFIHNGYYHLIFNCILQFALGTFLELVHKFWRVGIVYVLGVLAGSLAHSVSDPFLALAGASGGCYALIGAHVATIITNWKTMQVGWLKSPLNFLSSGAVRLSIILLIAGADTGFAIYERFNNPNESKVGFASHLGGFAAGVLVGVPVLRNLEIERWEKVCFWICIFLFAVFMSAAVLFNGFCEEQGWCPPTDWS 397
[Close]
BLAST of EF-hand domain-containing protein vs. TrEMBL
Match: A0A158QE63 (EF-hand domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS6938 PE=3 SV=1)

HSP 1 Score: 414.461 bits (1064), Expect = 4.640e-139
Identity = 202/382 (52.88%), Postives = 265/382 (69.37%), Query Frame = 1 
Query:   70 ENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPD--------RIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKNLCYATNFN 1191
            E  FR   D  E  GG+PL  L+  L +S +PP +  RF   AD +++  + Y+EF  Q+  EDS+ L KLA  KR +  AV  VAP         ++QR   D+ D  NWGE  V  Y EAY+C+PPP  IP IT SQI VF+YY I L+ DD+  NDVTA +GV ++SPLIY P +R +AWRF+ YMF+H GY HLIFNCI+Q  LGT LE+VHKFWRV IVY+LGVLAGSLAHS  D    L GASGGCYALIGAH AT++TNW TMQ  WL++P+NFLSSG  RL ++LL+AG DTG AIY+RF+    + +GF++H+GG  AG L+G+PVLRNLE++ WEK+CFW+ + L+ +FM  +++FN  C+ +  C  T+++
Sbjct:    8 EREFREHLDVYEREGGMPLGVLQRLLHDSGIPPARTKRFFRKADLNRDERVNYDEFLRQIMFEDSQFLHKLAFGKRALNRAVIAVAPQMARRKQRIQMQRNGIDETDLYNWGEENVNNYIEAYDCRPPPIFIPLITFSQIAVFVYYAIVLSQDDNPFNDVTATSGVPMKSPLIYLPTKRYQAWRFVSYMFIHNGYYHLIFNCILQFALGTFLELVHKFWRVGIVYVLGVLAGSLAHSVSDPFLALAGASGGCYALIGAHVATIITNWKTMQVGWLKSPLNFLSSGAVRLSIILLIAGADTGFAIYERFNNPNESKVGFASHLGGFAAGVLVGVPVLRNLEIERWEKVCFWICIFLFAVFMSAAVLFNGFCEEQGWCPPTDWS 389
[Close]
BLAST of EF-hand domain-containing protein vs. TrEMBL
Match: A0A0R3TLJ4 (EF-hand domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS8120 PE=3 SV=1)

HSP 1 Score: 410.223 bits (1053), Expect = 1.615e-137
Identity = 201/384 (52.34%), Postives = 262/384 (68.23%), Query Frame = 1 
Query:   55 IIDEIENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPD--------RIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKNLCYAT 1182
            ++   E  FR   D  E  GG+PL  L+  L  S + P +  +F   AD +++  + Y+EF  Q+  EDS+ L KLA  KR +  AV  VAP         ++Q+   D+ D  NWGE  V  Y EAY+C+PPP  IP ITLSQI VF+YY I  + DD+  NDVTA +GV +RSPLIY P +R +AWRF+ YMF+H GY HLIFNCI+Q VLGT LE+VHKFWRV IVY+LGVLAGSLAHS  D    L GASGGCYALIGAH AT++TNW TMQ  WL+ P+NFLSSG  RL ++LL+AG DTG AIY+RF+    + +GF++H+GG  AG L+G+PVLRNLE++ WEK+CFW+ + L+ +FM  +++FN  C+ +  C  T
Sbjct:    3 VLTRGEREFREHLDAHEREGGMPLEVLQGLLHNSSISPARTKQFFKKADLNRDERVNYDEFLRQIMFEDSQFLHKLAFGKRALNRAVIAVAPQMARRKQRIQMQKNGIDETDLYNWGEENVNNYVEAYDCRPPPIFIPLITLSQIVVFVYYAIVASQDDNPYNDVTATSGVPMRSPLIYLPTKRYQAWRFVSYMFIHNGYYHLIFNCILQFVLGTFLELVHKFWRVGIVYLLGVLAGSLAHSVSDPFLALAGASGGCYALIGAHVATIITNWKTMQANWLKTPLNFLSSGAVRLFIILLIAGVDTGFAIYERFNNPSESKVGFASHLGGFAAGVLVGVPVLRNLEIERWEKVCFWICVFLFAVFMSAAVLFNGFCEEQGWCPPT 386
[Close]
BLAST of EF-hand domain-containing protein vs. TrEMBL
Match: A0A4V3SFL2 (Rhomboid domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_004034 PE=3 SV=1)

HSP 1 Score: 403.675 bits (1036), Expect = 7.692e-135
Identity = 199/392 (50.77%), Postives = 265/392 (67.60%), Query Frame = 1 
Query:   31 MKSRKSQKIIDEIENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAP--------DRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKNLCYAT 1182
            M   +   +   ++ NF+P FD+ +  G IPL EL++ L +S LP  +++  +  ADKD N  I Y+EF  Q+  ED    ++L +R R++  AV  + P        D + +   D  D  NWGE  V  Y EAY+C+PPP  IP ITL +IGVFIYY +    D D  NDVTA +GV + SPLIY P +R EAWRF+ YMF+H GY+HL FNCI+QLVLG LLE+VHKFWR  +VY+LG++AGSLAHS  D    L GASGGCYALIGAH A+++ NW  MQ +WL NP+NFLSSGV RL ++LLLAG DTG+AIY R+   + T +GFSAH+GG +AG L+GIP+LRNL+V+ WEK+CFW+ +V++  F+  +I+FN  C   N C A+
Sbjct:    1 MSVVRRDSLRRHLDKNFKPAFDEYDADG-IPLAELKSLLADSDLPERQISVLVKAADKDGNQRIAYDEFVRQIMSEDEGVWKRLRIRARVLNRAVLAIDPAAGRRHQQDVMVKSGIDSPDTYNWGEADVDNYVEAYDCRPPPIFIPVITLVEIGVFIYYALLHAWDSDPYNDVTAASGVPIYSPLIYDPRKRHEAWRFLTYMFIHNGYVHLAFNCILQLVLGMLLELVHKFWRCGLVYLLGIIAGSLAHSITDPYVLLAGASGGCYALIGAHLASIIINWKAMQDKWLDNPINFLSSGVVRLFLILLLAGSDTGLAIYARYKNPLGTRVGFSAHLGGFVAGILLGIPILRNLQVEKWEKVCFWICIVIFACFVTAAILFNGFCIRVNYCPAS 391
[Close]
BLAST of EF-hand domain-containing protein vs. TrEMBL
Match: W6U9J4 (Rhomboid-related protein OS=Echinococcus granulosus OX=6210 GN=EGR_09968 PE=3 SV=1)

HSP 1 Score: 402.519 bits (1033), Expect = 4.553e-134
Identity = 202/382 (52.88%), Postives = 254/382 (66.49%), Query Frame = 1 
Query:   70 ENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPD--------RIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKNLCYATNFN 1191
            E   R   D  E  GG+PL  L+  L ES +PP +  RF   AD + +  + Y+EF  Q+  EDS  L+KLA     +  AV  VAP         ++Q+   D+ D  NWGE  V  Y EAY+C+PPP  IP IT +QI VF YY +    D D  NDVTA +GV   SPLIY P +R +AWRF+ YMF+H GY+HLIFNC++QL LGTLLE+VHKFWRV IVY+LGV+AGSLAHS  D    L GASGGCYALIGAH AT++TNW TMQ  WL+NP+NFLSSG  RL  +LLLAG DTG AIY+RF+      +GF AH+GG  AG L+GIPVLRNLEV+ WEK+CFWV + L+  FM  +++FN  C+ +  C  T+++
Sbjct:   37 ERELRERLDTYEREGGMPLDVLQRLLNESDIPPTRTKRFFKKADVNCDQRVNYDEFLRQIMFEDSAFLQKLAFGSIALNKAVIAVAPQTARRKQRLQMQKSGIDETDLYNWGEADVNNYIEAYDCRPPPIFIPFITFAQIAVFTYYAVVAAHDVDPFNDVTASSGVPFYSPLIYLPQKRYQAWRFLSYMFIHNGYVHLIFNCVLQLALGTLLELVHKFWRVGIVYLLGVVAGSLAHSVSDPFIALAGASGGCYALIGAHVATIITNWKTMQAGWLKNPMNFLSSGAVRLTFILLLAGADTGFAIYERFTNPSVAKVGFVAHLGGFAAGVLVGIPVLRNLEVERWEKVCFWVCIFLFAAFMSAAVLFNGFCEEQGWCPPTDWS 418
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Cavefish
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:103039963])

HSP 1 Score: 174.096 bits (440), Expect = 2.425e-49
Identity = 128/408 (31.37%), Postives = 205/408 (50.25%), Query Frame = 1 
Query:   25 FSMKS-----RKSQKIIDEIENNFRPLFDQKEVTGGIPLVELRTSLRE--SKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF---SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDS 1161
            FSMK+        QK+ + ++  + P     E +G I     R  L    S+L P+K+   L  AD + +  I Y++F + ++ + S +  +                   L L +R++R+      P  + R                K Y ++Y   PPP++I AIT++++ VF+YY ++L   D     V++ +   L+SPL Y P  R +AWR++ Y+F+H G  HL  N  MQL++G  LE+VH   R+ ++Y+ GVLAGSLA S  D T  +VG+SGG YAL+ AH A VV NW  M+ Q+           +FR+ + L+    + G A++ RF   +        F AH+GG + G  +G+ VL+N E +  E+  FW+   +Y LF+   I +N+   S
Sbjct:    6 FSMKTFGDSINARQKLAELLQKKYDP-----ESSGFISTERFRDLLEAHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSNKRSNSFRRAILQGSRQLKNSSLTEEVGLGLSQRLVRHVAYETLPREVDR----------------KWYFDSYTYCPPPWLILAITIAEMVVFVYYGLQL---DRWVLQVSSPS--FLKSPLPYHPQHRAQAWRYLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGAARIGLIYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWSGMKCQF----------KLFRMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVVVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYALFIFCGIFWNIFAYS 377
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Cavefish
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:103039963])

HSP 1 Score: 174.096 bits (440), Expect = 3.094e-49
Identity = 125/390 (32.05%), Postives = 200/390 (51.28%), Query Frame = 1 
Query:   70 ENNFRPLFDQ--KEVTGGIPLVELRTSLRE--SKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF---SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDS 1161
            E+ ++ LFD+   E +G I     R  L    S+L P+K+   L  AD + +  I Y++F + ++ + S +  +                   L L +R++R+      P  + R                K Y ++Y   PPP++I AIT++++ VF+YY ++L   D     V++ +   L+SPL Y P  R +AWR++ Y+F+H G  HL  N  MQL++G  LE+VH   R+ ++Y+ GVLAGSLA S  D T  +VG+SGG YAL+ AH A VV NW  M+ Q+           +FR+ + L+    + G A++ RF   +        F AH+GG + G  +G+ VL+N E +  E+  FW+   +Y LF+   I +N+   S
Sbjct:   36 EDQWKSLFDKYDPESSGFISTERFRDLLEAHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSNKRSNSFRRAILQGSRQLKNSSLTEEVGLGLSQRLVRHVAYETLPREVDR----------------KWYFDSYTYCPPPWLILAITIAEMVVFVYYGLQL---DRWVLQVSSPS--FLKSPLPYHPQHRAQAWRYLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGAARIGLIYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWSGMKCQF----------KLFRMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVVVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYALFIFCGIFWNIFAYS 394
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Cavefish
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:103039963])

HSP 1 Score: 174.096 bits (440), Expect = 3.094e-49
Identity = 125/390 (32.05%), Postives = 200/390 (51.28%), Query Frame = 1 
Query:   70 ENNFRPLFDQ--KEVTGGIPLVELRTSLRE--SKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF---SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDS 1161
            E+ ++ LFD+   E +G I     R  L    S+L P+K+   L  AD + +  I Y++F + ++ + S +  +                   L L +R++R+      P  + R                K Y ++Y   PPP++I AIT++++ VF+YY ++L   D     V++ +   L+SPL Y P  R +AWR++ Y+F+H G  HL  N  MQL++G  LE+VH   R+ ++Y+ GVLAGSLA S  D T  +VG+SGG YAL+ AH A VV NW  M+ Q+           +FR+ + L+    + G A++ RF   +        F AH+GG + G  +G+ VL+N E +  E+  FW+   +Y LF+   I +N+   S
Sbjct:   36 EDQWKSLFDKYDPESSGFISTERFRDLLEAHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSNKRSNSFRRAILQGSRQLKNSSLTEEVGLGLSQRLVRHVAYETLPREVDR----------------KWYFDSYTYCPPPWLILAITIAEMVVFVYYGLQL---DRWVLQVSSPS--FLKSPLPYHPQHRAQAWRYLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGAARIGLIYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWSGMKCQF----------KLFRMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVVVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYALFIFCGIFWNIFAYS 394
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Cavefish
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:103039963])

HSP 1 Score: 168.318 bits (425), Expect = 2.197e-47
Identity = 120/377 (31.83%), Postives = 192/377 (50.93%), Query Frame = 1 
Query:  103 EVTGGIPLVELRTSLRE--SKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF---SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDS 1161
             ++G I     R  L    S+L P+K+   L  AD + +  I Y++F + ++ + S +  +                   L L +R++R+      P  + R                K Y ++Y   PPP++I AIT++++ VF+YY ++L   D     V++ +   L+SPL Y P  R +AWR++ Y+F+H G  HL  N  MQL++G  LE+VH   R+ ++Y+ GVLAGSLA S  D T  +VG+SGG YAL+ AH A VV NW  M+ Q+           +FR+ + L+    + G A++ RF   +        F AH+GG + G  +G+ VL+N E +  E+  FW+   +Y LF+   I +N+   S
Sbjct:   10 SISGFISTERFRDLLEAHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSNKRSNSFRRAILQGSRQLKNSSLTEEVGLGLSQRLVRHVAYETLPREVDR----------------KWYFDSYTYCPPPWLILAITIAEMVVFVYYGLQL---DRWVLQVSSPS--FLKSPLPYHPQHRAQAWRYLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGAARIGLIYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWSGMKCQF----------KLFRMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVVVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYALFIFCGIFWNIFAYS 355
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Cavefish
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:103039963])

HSP 1 Score: 169.088 bits (427), Expect = 2.281e-47
Identity = 121/377 (32.10%), Postives = 192/377 (50.93%), Query Frame = 1 
Query:  103 EVTGGIPLVELRTSLRE--SKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF---SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDS 1161
            E +G I     R  L    S+L P+K+   L  AD + +  I Y++F + ++ + S +  +                   L L +R++R+      P  + R                K Y ++Y   PPP++I AIT++++ VF+YY ++L   D     V++ +   L+SPL Y P  R +AWR++ Y+F+H G  HL  N  MQL++G  LE+VH   R+ ++Y+ GVLAGSLA S  D T  +VG+SGG YAL+ AH A VV NW  M+ Q+           +FR+ + L+    + G A++ RF   +        F AH+GG + G  +G+ VL+N E +  E+  FW+   +Y LF+   I +N+   S
Sbjct:   41 ESSGFISTERFRDLLEAHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSNKRSNSFRRAILQGSRQLKNSSLTEEVGLGLSQRLVRHVAYETLPREVDR----------------KWYFDSYTYCPPPWLILAITIAEMVVFVYYGLQL---DRWVLQVSSPS--FLKSPLPYHPQHRAQAWRYLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGAARIGLIYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWSGMKCQF----------KLFRMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVVVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYALFIFCGIFWNIFAYS 386
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Sea Lamprey
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 168.703 bits (426), Expect = 4.174e-49
Identity = 108/253 (42.69%), Postives = 148/253 (58.50%), Query Frame = 1 
Query:  394 KTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF-SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
            + Y E  NC PPP  I  I+L ++GVFIYY +       +   +T  +G+   SP IY P RR EAWRF+ YM +H G  H+I N I+QL+LG  LE+VHK  RV +VY+ GV+AGSLA S FD    LVGASGG YALIG +F  VV N+  M+  +          GVFRL+ +  +   D G+AIY RF +KE+   + F AHI G LAG  +G  V  + +    +   FWV L+ + +  + ++ FN+
Sbjct:   53 EKYLERANCLPPPIFIMLISLLELGVFIYYAVW----KPQKQWITLDSGIS-NSPFIYRPDRRQEAWRFVSYMLVHAGVQHIINNLIVQLILGLPLELVHKGHRVGLVYLAGVVAGSLASSVFDPCVQLVGASGGGYALIGGYFMNVVVNFKEMKPLF----------GVFRLLFIGSIVLSDVGVAIYRRFIAKEIAQQVSFVAHIAGGLAGVSMGYVVFTSYDQSLVKDPRFWVCLLGFAICTLVAVAFNI 290
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Nematostella
Match: EDO39142 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB02])

HSP 1 Score: 51.6026 bits (122), Expect = 4.929e-7
Identity = 29/102 (28.43%), Postives = 50/102 (49.02%), Query Frame = 1 
Query:  586 EAWRFIGYMFLH--------QGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQW 867
            + +R +  +FLH         G IHL+ N I Q+++G ++EI     R A +Y++  L GSL    F      VG+SG  + LI    A     + ++++ +
Sbjct:  278 QGYRLMSAVFLHLGNYGNCLHGIIHLLLNLIFQVIIGRMIEIEIGTIRTACIYLVSGLGGSLVSGVFTPLTPQVGSSGALFGLIALMLAHYCYYYPSLRRPY 379
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Medaka
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:101157837])

HSP 1 Score: 174.096 bits (440), Expect = 2.402e-49
Identity = 119/358 (33.24%), Postives = 185/358 (51.68%), Query Frame = 1 
Query:  154 SKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF---SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDS 1161
            S+L P+K+   L  AD + +  I Y++F + ++ + S +  +                   L L +R++R+      P  + R                K Y ++Y   PPP+ I AIT++++ VFIYY  KL   D     V++ +   L+SPL Y P  R +AWR+  Y+F+H G  HL  N  MQL++G  LE+VH   R+ +VY+ GVLAGSLA S  D T  +VG+SGG YAL+ AH A VV NW  M+ Q+           +FR+ + L+    + G A++ RF   +        F AH+GG L G  +G+ VL+N E +  E+  FW+   +Y LF++ ++ +N+   S
Sbjct:   54 SELDPHKLEVLLALADGNADGKICYQDFVNLMSNKRSNSFRRAILQGSRQLKGCSLSDEAGLGLSQRLVRHVAYETLPREVDR----------------KWYFDSYTYCPPPWFILAITIAEVAVFIYYGFKL---DRLVLQVSSPS--FLKSPLPYHPQLRAQAWRYFSYIFMHTGIEHLSLNMAMQLLVGVPLEMVHGALRIGLVYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWSGMKCQF----------KLFRMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVLVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYTLFVLCAVFWNIFAYS 380
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Medaka
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:101157837])

HSP 1 Score: 174.481 bits (441), Expect = 2.728e-49
Identity = 119/358 (33.24%), Postives = 185/358 (51.68%), Query Frame = 1 
Query:  154 SKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF---SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDS 1161
            S+L P+K+   L  AD + +  I Y++F + ++ + S +  +                   L L +R++R+      P  + R                K Y ++Y   PPP+ I AIT++++ VFIYY  KL   D     V++ +   L+SPL Y P  R +AWR+  Y+F+H G  HL  N  MQL++G  LE+VH   R+ +VY+ GVLAGSLA S  D T  +VG+SGG YAL+ AH A VV NW  M+ Q+           +FR+ + L+    + G A++ RF   +        F AH+GG L G  +G+ VL+N E +  E+  FW+   +Y LF++ ++ +N+   S
Sbjct:   71 SELDPHKLEVLLALADGNADGKICYQDFVNLMSNKRSNSFRRAILQGSRQLKGCSLSDEAGLGLSQRLVRHVAYETLPREVDR----------------KWYFDSYTYCPPPWFILAITIAEVAVFIYYGFKL---DRLVLQVSSPS--FLKSPLPYHPQLRAQAWRYFSYIFMHTGIEHLSLNMAMQLLVGVPLEMVHGALRIGLVYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWSGMKCQF----------KLFRMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVLVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYTLFVLCAVFWNIFAYS 397
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Medaka
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:101157837])

HSP 1 Score: 174.481 bits (441), Expect = 3.192e-49
Identity = 119/358 (33.24%), Postives = 185/358 (51.68%), Query Frame = 1 
Query:  154 SKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEK-------------------LALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRF---SKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDS 1161
            S+L P+K+   L  AD + +  I Y++F + ++ + S +  +                   L L +R++R+      P  + R                K Y ++Y   PPP+ I AIT++++ VFIYY  KL   D     V++ +   L+SPL Y P  R +AWR+  Y+F+H G  HL  N  MQL++G  LE+VH   R+ +VY+ GVLAGSLA S  D T  +VG+SGG YAL+ AH A VV NW  M+ Q+           +FR+ + L+    + G A++ RF   +        F AH+GG L G  +G+ VL+N E +  E+  FW+   +Y LF++ ++ +N+   S
Sbjct:   79 SELDPHKLEVLLALADGNADGKICYQDFVNLMSNKRSNSFRRAILQGSRQLKGCSLSDEAGLGLSQRLVRHVAYETLPREVDR----------------KWYFDSYTYCPPPWFILAITIAEVAVFIYYGFKL---DRLVLQVSSPS--FLKSPLPYHPQLRAQAWRYFSYIFMHTGIEHLSLNMAMQLLVGVPLEMVHGALRIGLVYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWSGMKCQF----------KLFRMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVLVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYTLFVLCAVFWNIFAYS 405
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Medaka
Match: rhbdl2 (rhomboid like 2 [Source:NCBI gene;Acc:101175267])

HSP 1 Score: 166.007 bits (419), Expect = 2.443e-47
Identity = 100/252 (39.68%), Postives = 143/252 (56.75%), Query Frame = 1 
Query:  394 KTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
              Y E  NC PPP  I  I+++++ VFIYY +       +   VT   G+   SPL Y P  R EAWRF+ YMF+H G  H++ N +MQL++G  LE+VHK + V +VY+ GV+AGSLA S FD    LVGASGG YAL+G +F   + N+  M      NP+      VFR+++++ + GGD G A+Y RF       + F AH+GG  AG  IG         K  +   FWV +  Y +F+  ++++N+
Sbjct:   52 SVYLEKANCFPPPIFIILISIAELAVFIYYAVW----KPQKQWVTLDEGI-WNSPLTYRPDHRQEAWRFVSYMFVHAGVEHIVGNLLMQLLVGIPLEMVHKGFEVGMVYMAGVIAGSLASSIFDPFSGLVGASGGVYALLGGYFMNAIVNFREM------NPI----FRVFRIVIIVFIVGGDFGFALYRRFVAHDNLQVSFVAHLGGIAAGMTIGFVFFSAYNQKLLKDFRFWVCIAGYIVFLFFAVVYNI 288
[Close]
BLAST of EF-hand domain-containing protein vs. Ensembl Medaka
Match: rhbdl2 (rhomboid like 2 [Source:NCBI gene;Acc:101175267])

HSP 1 Score: 150.984 bits (380), Expect = 1.028e-41
Identity = 97/252 (38.49%), Postives = 137/252 (54.37%), Query Frame = 1 
Query:  394 KTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNV 1149
              Y E  NC PPP  I  I+++++ VFIYY +       +   VT   G+   SPL Y P  R EAWRF+ YMF+H G  H++ N +MQL++G  LE+VHK + V +VY+ GV+AGSLA S FD    LVGASGG YAL+G +F   +     +  Q+    ++FLS           + GGD G A+Y RF       + F AH+GG  AG  IG         K  +   FWV +  Y +F+  ++++N+
Sbjct:   48 SVYLEKANCFPPPIFIILISIAELAVFIYYAVW----KPQKQWVTLDEGI-WNSPLTYRPDHRQEAWRFVSYMFVHAGVEHIVGNLLMQLLVGIPLEMVHKGFEVGMVYMAGVIAGSLASSIFDPFSGLVGASGGVYALLGGYFMNAIVVRGCI--QFCSIKLHFLS-----------IVGGDFGFALYRRFVAHDNLQVSFVAHLGGIAAGMTIGFVFFSAYNQKLLKDFRFWVCIAGYIVFLFFAVVYNI 281
[Close]
BLAST of EF-hand domain-containing protein vs. Planmine SMEST
Match: SMESG000001621.1 (SMESG000001621.1)

HSP 1 Score: 777.704 bits (2007), Expect = 0.000e+0
Identity = 389/389 (100.00%), Postives = 389/389 (100.00%), Query Frame = 1 
Query:   31 MKSRKSQKIIDEIENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKNLCYATNFNFP 1197
            MKSRKSQKIIDEIENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHIGGALAGFLIGIPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKNLCYATNFNFP
Sbjct:    1 MKSRKSQKIIDEIENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPDRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHIGGALAGFLIGIPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKNLCYATNFNFP 389
[Close]
BLAST of EF-hand domain-containing protein vs. Planmine SMEST
Match: SMESG000053833.1 (SMESG000053833.1)

HSP 1 Score: 265.774 bits (678), Expect = 3.573e-84
Identity = 150/380 (39.47%), Postives = 227/380 (59.74%), Query Frame = 1 
Query:   67 IENNFRPLFDQKEVTGGIPLVELRTSLRESKL--PPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPDRI--------QRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQ---NPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHXXXXXXXXXXXXPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKN 1167
            ++  F+ +FD+ + + G+P   L   LR   L  P  ++NRF+   D +++  +TYEEF   +   + R    ++  K+I+ +      PD I        +     +++         ++Y +AY+C PPP  IP I ++Q+  F++Y ++L  +DD  N ++  TG+  +SPLI+  ++RIE WRF  YM +HQGY+H+IFNC++QL+LG  LE+VHKFWRV  VY+ GVLAGSLA S  D    LVG+SGG YALIGAHFA V+ NWD +Q+ WL+   N +NF++SGV RL+ L+     D G ++Y R   ++      ++HIGG +AG L GIP LRN+  K WE   FWVSL +Y   +  +I++N+     N
Sbjct:   46 LDQTFKTMFDEYD-SMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPR---DISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCLIQLLLGIPLELVHKFWRVGPVYLSGVLAGSLASSIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGYN 421
[Close]
BLAST of EF-hand domain-containing protein vs. Planmine SMEST
Match: SMESG000066428.1 (SMESG000066428.1)

HSP 1 Score: 53.9138 bits (128), Expect = 1.890e-7
Identity = 27/94 (28.72%), Postives = 45/94 (47.87%), Query Frame = 1 
Query:  586 EAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQW 867
            + +R    +FLH G +HL    +MQ       E +  + R A++YIL  + G+L  + F   K   G SG C+A +G      + +W  ++  W
Sbjct:  473 QIYRLFISLFLHVGIVHLAITVLMQAFFLRDFEKLMGWLRTALIYILSGVMGNLMSAVFLPYKVEAGPSGSCFAFLGIIIIEFLKSWKLIKSPW 566
[Close]
BLAST of EF-hand domain-containing protein vs. Planmine SMEST
Match: SMESG000032990.1 (SMESG000032990.1)

HSP 1 Score: 53.5286 bits (127), Expect = 2.579e-7
Identity = 31/108 (28.70%), Postives = 55/108 (50.93%), Query Frame = 1 
Query:  565 YSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNF 888
            Y   R  + +RF+  +F++     LI    +QL +   LE +  + R++I+YIL  + G++    F   +   GASG  +A++   FA  + +W  +Q+ W   PV F
Sbjct:  496 YDQNRPDQFYRFLIAIFVNSSLGSLIVTLCIQLSIMRDLEKMSGWHRISIIYILSGIMGNMCSGIFLPYQVQTGASGSIFAMLAMTFAEFLQSWKIVQRPW---PVFF 600
The following BLAST results are available for this feature:
BLAST of EF-hand domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RHBDL25.567e-5041.83rhomboid like 2 [Source:HGNC Symbol;Acc:HGNC:16083... [more]
RHBDL25.567e-5041.83rhomboid like 2 [Source:HGNC Symbol;Acc:HGNC:16083... [more]
RHBDL31.956e-4629.90rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502... [more]
RHBDL31.526e-4429.76rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502... [more]
RHBDL11.424e-4130.06rhomboid like 1 [Source:HGNC Symbol;Acc:HGNC:10007... [more]
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rom-15.588e-4232.72Rhomboid-related protein 1 [Source:UniProtKB/Swis... [more]
rom-22.511e-3132.50Rhomboid-related protein 2 [Source:UniProtKB/Swis... [more]
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rho-41.443e-5332.70gene:FBgn0030318 transcript:FBtr0073519[more]
rho-41.443e-5332.70gene:FBgn0030318 transcript:FBtr0073518[more]
stet2.882e-4632.32gene:FBgn0020248 transcript:FBtr0072712[more]
stet4.241e-4537.41gene:FBgn0020248 transcript:FBtr0072713[more]
rho9.555e-3635.74gene:FBgn0004635 transcript:FBtr0072694[more]
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rhbdl25.058e-5240.73rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
rhbdl25.058e-5240.73rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
rhbdl25.058e-5240.73rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
rhbdl25.058e-5240.73rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
rhbdl25.058e-5240.73rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
eif4a11.374e-4941.27eukaryotic translation initiation factor 4A1 [Sour... [more]
rhbdf21.449e-730.23rhomboid 5 homolog 2 [Source:NCBI gene;Acc:1000366... [more]
rhbdf21.455e-730.23rhomboid 5 homolog 2 [Source:NCBI gene;Acc:1000366... [more]
rhbdf21.458e-730.23rhomboid 5 homolog 2 [Source:NCBI gene;Acc:1000366... [more]
rhbdf21.510e-730.23rhomboid 5 homolog 2 [Source:NCBI gene;Acc:1000366... [more]
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rhbdl22.858e-5241.51rhomboid like 2 [Source:MGI Symbol;Acc:MGI:3608413... [more]
Rhbdl22.858e-5241.51rhomboid like 2 [Source:MGI Symbol;Acc:MGI:3608413... [more]
Rhbdl36.128e-4630.57rhomboid like 3 [Source:MGI Symbol;Acc:MGI:2179276... [more]
Rhbdl11.489e-4130.34rhomboid like 1 [Source:MGI Symbol;Acc:MGI:2384891... [more]
Rhbdl16.339e-3728.89rhomboid like 1 [Source:MGI Symbol;Acc:MGI:2384891... [more]
back to top
BLAST of EF-hand domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A2AGA4|RHBL2_MOUSE1.999e-5141.51Rhomboid-related protein 2 OS=Mus musculus OX=1009... [more]
sp|Q9NX52|RHBL2_HUMAN2.673e-4941.83Rhomboid-related protein 2 OS=Homo sapiens OX=9606... [more]
sp|P58872|RHBL3_HUMAN9.395e-4629.90Rhomboid-related protein 3 OS=Homo sapiens OX=9606... [more]
sp|P58873|RHBL3_MOUSE4.287e-4530.57Rhomboid-related protein 3 OS=Mus musculus OX=1009... [more]
sp|Q19821|RHOM1_CAEEL7.108e-4132.72Rhomboid-related protein 1 OS=Caenorhabditis elega... [more]
back to top
BLAST of EF-hand domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A564YNU88.674e-14251.65EF-hand domain-containing protein OS=Hymenolepis d... [more]
A0A158QE634.640e-13952.88EF-hand domain-containing protein OS=Hymenolepis d... [more]
A0A0R3TLJ41.615e-13752.34EF-hand domain-containing protein OS=Rodentolepis ... [more]
A0A4V3SFL27.692e-13550.77Rhomboid domain-containing protein OS=Opisthorchis... [more]
W6U9J44.553e-13452.88Rhomboid-related protein OS=Echinococcus granulosu... [more]
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rhbdl32.425e-4931.37rhomboid like 3 [Source:NCBI gene;Acc:103039963][more]
rhbdl33.094e-4932.05rhomboid like 3 [Source:NCBI gene;Acc:103039963][more]
rhbdl33.094e-4932.05rhomboid like 3 [Source:NCBI gene;Acc:103039963][more]
rhbdl32.197e-4731.83rhomboid like 3 [Source:NCBI gene;Acc:103039963][more]
rhbdl32.281e-4732.10rhomboid like 3 [Source:NCBI gene;Acc:103039963][more]
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rhbdl24.174e-4942.69rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO391424.929e-728.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of EF-hand domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rhbdl32.402e-4933.24rhomboid like 3 [Source:NCBI gene;Acc:101157837][more]
rhbdl32.728e-4933.24rhomboid like 3 [Source:NCBI gene;Acc:101157837][more]
rhbdl33.192e-4933.24rhomboid like 3 [Source:NCBI gene;Acc:101157837][more]
rhbdl22.443e-4739.68rhomboid like 2 [Source:NCBI gene;Acc:101175267][more]
rhbdl21.028e-4138.49rhomboid like 2 [Source:NCBI gene;Acc:101175267][more]
back to top
BLAST of EF-hand domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000001621.10.000e+0100.00SMESG000001621.1[more]
SMESG000053833.13.573e-8439.47SMESG000053833.1[more]
SMESG000066428.11.890e-728.72SMESG000066428.1[more]
SMESG000032990.12.579e-728.70SMESG000032990.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005861 ID=SMED30005861|Name=EF-hand domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1410bp
TAAACATTTTATCCAATCTATTGTTTTAGTATGAAATCTCGTAAAAGTCA
AAAAATAATTGATGAAATCGAAAATAATTTCAGGCCATTATTTGATCAAA
AAGAAGTTACTGGAGGAATACCATTAGTTGAATTGCGAACTTCTTTGAGA
GAATCCAAATTACCTCCAAATAAAGTGAATAGATTCTTAAACAATGCAGA
CAAAGATCAAAATTCTTTAATTACATATGAAGAATTTTATGATCAATTAA
CAAGGGAAGACTCACGTACACTGGAAAAATTAGCTTTAAGGAAGAGAATA
ATTCGTAATGCTGTCAGAATAGTAGCACCAGATCGTATTCAAAGAGTGAA
TGCAGATCAACAGGATTATTGTAATTGGGGAGAAGGAACGGTAAAAACAT
ATTCCGAAGCATATAACTGTAAACCTCCACCTTTTATAATACCGGCAATA
ACTTTATCTCAGATAGGAGTTTTCATTTACTATGTTATTAAACTGAACAC
TGATGATGATCGAACAAATGACGTGACAGCTCGAACAGGTGTTCATTTGA
GAAGTCCTCTTATTTACAGTCCATATAGAAGAATAGAAGCATGGAGATTT
ATTGGTTATATGTTTTTGCATCAAGGCTACATACATTTGATTTTTAATTG
CATCATGCAACTGGTGCTGGGAACATTATTAGAAATTGTCCATAAATTCT
GGCGAGTTGCAATAGTTTACATACTTGGTGTTTTAGCAGGTTCTTTGGCT
CATTCTTGCTTTGACTCAACAAAATACCTTGTTGGAGCCAGTGGCGGATG
TTATGCATTAATTGGAGCACATTTTGCTACAGTTGTAACAAATTGGGATA
CAATGCAAAAGCAATGGTTGCAAAATCCTGTTAATTTTCTATCAAGTGGT
GTTTTTCGCTTGATTGTACTACTTCTATTAGCTGGGGGTGACACCGGTAT
TGCTATCTATGATAGGTTTTCTAAAGAAGTACCAACTCCGATTGGATTTA
GTGCTCACATTGGAGGTGCTTTGGCAGGTTTTTTAATTGGTATTCCTGTT
CTACGAAATCTTGAAGTCAAGCCTTGGGAGAAAATCTGTTTTTGGGTCAG
TTTAGTTTTATACTGTTTATTCATGATCGGTTCCATTATTTTTAATGTGA
TTTGTGATTCGAAAAATTTATGTTATGCTACAAATTTTAATTTCCCATAA
AACATTTGATATTGTGTAGAAATTTTCAAGTTTTACTCAGATTGTTTCTT
TAGTGATTATTTGTTGGTATTTGATAAGTGTTATTTCTTTACAATTCTAC
TAAAATAATTTTACATAAACTCTGGCCTTTTGTTTTATACTATGATTTGT
ATTCTATACTATGAAATTTTTTGTAGTGCAATGTAACTGATTCAATAAAT
AAATATCGTT
back to top

protein sequence of SMED30005861-orf-1

>SMED30005861-orf-1 ID=SMED30005861-orf-1|Name=SMED30005861-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=390bp
MKSRKSQKIIDEIENNFRPLFDQKEVTGGIPLVELRTSLRESKLPPNKVN
RFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAP
DRIQRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIY
YVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGY
IHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYL
VGASGGCYALIGAHFATVVTNWDTMQKQWLQNPVNFLSSGVFRLIVLLLL
AGGDTGIAIYDRFSKEVPTPIGFSAHIGGALAGFLIGIPVLRNLEVKPWE
KICFWVSLVLYCLFMIGSIIFNVICDSKNLCYATNFNFP*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002056medial muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR022764Peptidase_S54_rhomboid_dom
IPR011992EF-hand-dom_pair
IPR017213Peptidase_S54_rhomboid_met
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0004252serine-type endopeptidase activity
GO:0005509calcium ion binding
GO:0008233peptidase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis