Membrane-bound transcription factor peptidase, site 1

Overview
NameMembrane-bound transcription factor peptidase, site 1
Smed IDSMED30005850
Length (bp)2097
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Membrane-bound transcription factor peptidase, site 1 (SMED30005850) t-SNE clustered cells

Violin plots show distribution of expression levels for Membrane-bound transcription factor peptidase, site 1 (SMED30005850) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Membrane-bound transcription factor peptidase, site 1 (SMED30005850) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Membrane-bound transcription factor peptidase, site 1 (SMED30005850) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005850

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30005850SMESG000010258.1 SmedASXL_012122SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Human
Match: MBTPS1 (membrane bound transcription factor peptidase, site 1 [Source:HGNC Symbol;Acc:HGNC:15456])

HSP 1 Score: 506.908 bits (1304), Expect = 2.413e-166
Identity = 280/611 (45.83%), Postives = 389/611 (63.67%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKN---LTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLCRR-------------PSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGR+KPD+VTYG  +  + + G C+ +SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  PSY+DLTE PYMWPY SQP+Y   MP ++N+TI+N M V+G     P +     +NGD I V+ ++S  LWPW+GYLA+ I+V  + + W+GIA+G+++  V S      KN    T+ +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LG+ F CF++S YGTL++VD EEE+F  E  KL +DV +NGLSL++F++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +G+  + N  + Y SG  I++FP     I+     +  KD G E+LK  +  V +  ILGLY   +I +   GRI +YGDSNCLD + R KDC WLLD+LLQY+  G     LS   +  +   GA    P+R + + L ++S V+++  G+    + LP C R             PSN         + +D   +P+  + RPQ+
Sbjct:  379 ELPGGYGRMKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAEQTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDV-DNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTLANHDMYYASGCSIAKFPEDGVVIT-----QTFKDQGLEVLKQETAVVENVPILGLY---QIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKP-RPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQV 972
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Fly
Match: S1P (gene:FBgn0037105 transcript:FBtr0078466)

HSP 1 Score: 385.185 bits (988), Expect = 1.270e-120
Identity = 240/619 (38.77%), Postives = 341/619 (55.09%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKP--SPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVS-TRVR--DAAILGLYS--GPRIQSG-----------------------------------------------NHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVK-SDLGANKFPPKRCQ----------NSRLFKFSAVIKSQNGEQ 1704
            E+P GYGR+  D+VTYG+Q+  + +   C+ +SGTSV+SP VA A ALL       +G        +PAS+KQ ++ GA +L     N+FEQG GKLNL+ + + LL  +P+ +  P+Y+D T+  YMWPYSSQPLY  +   I N+TI+N +SV+      P +       G  ++VS   S  +WPWTG++++ I V  E   ++G+ +G I  V++S     ++   T +  P+  KV P P R  RILWDQ+H+LRYPP YIPRD+++ + +PLDW  DHIHTNF+D Y +LRN  Y+I++L   F CFN+S+YG L+IVDPE  F + E   L ++V + GL+++VF +WYN  VM  ++FFDENTR WWTPDTGGANIPALN LL PFGI F D V +G  K+ +  + Y SG  I +FP +      ++   +L D G  ++   + ++V   D  I G++      IQS                                                N GRI+VYGDSNCLD T  +K C WLL + L ++   H S  L ++  I +   L     P +  Q          N   FK+ A  K  N E+
Sbjct:  330 ELPLGYGRMGLDIVTYGSQVEGSDVRKGCRRLSGTSVSSPVVAGAAALL------ISGAFQKIDYINPASLKQVLIEGAEKL--PHYNMFEQGAGKLNLLKSMQLLLSYKPKITLIPAYLDFTQN-YMWPYSSQPLYYGSSVAIANVTILNGISVTSHIVGIPKWIPDFENQGQFLQVSAQVSPIVWPWTGWMSVFIAVKKEGENFEGVCKGSITLVLESFKQTTNETHVTEVDFPLTIKVTPKPPRNKRILWDQYHSLRYPPRYIPRDDLKVKLDPLDWRADHIHTNFRDMYTHLRNVGYYIDVLREPFTCFNASDYGALLIVDPERGFGDEEINALQENVYKRGLNVVVFGDWYNTTVMKKIKFFDENTRQWWTPDTGGANIPALNDLLKPFGIAFGDFVGEGHFKLGDHSMYYASGATIVKFPMNP---GDIIVGTKLNDQGLSIINSKTPSKVAKLDVPIFGMFQTKANSIQSNEEIVVNAESNLAEAIPTDYSTFKNRVLLLRTKQRSISFAKSNNHETKNEGRIAVYGDSNCLDSTHLEKACYWLLITFLDFAINSHKSSLLQNLNRITEFHKLERAPLPLRISQSIIKSRSQDNNCEQFKWLAPTKQNNAEE 936
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Zebrafish
Match: mbtps1 (membrane-bound transcription factor peptidase, site 1 [Source:ZFIN;Acc:ZDB-GENE-030131-4909])

HSP 1 Score: 513.072 bits (1320), Expect = 1.086e-168
Identity = 280/611 (45.83%), Postives = 396/611 (64.81%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS---KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGRVKPD+VTYG+ +  + L   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P++     +NGD + V+V++S  LWPW GYLA+ I+V  + + W+GIA+G+++  V S    +SA    +T+ +K+P+K K++PTP R  RILWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LG+   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLIVF++WYN  VM  ++F+DENTR WW PDTGGAN+PALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP        ++ A+ LKD G E+LK  +  V +  +LGLY  P   S   GRI++YGDSNC+D + R KDC WLLD+LLQY+        L+   + +    G ++  P+R + + L+++S V+++  G+    + LP C               PSN         + +D   +P+   YRPQ+
Sbjct:  394 ELPGGYGRVKPDIVTYGSGVRGSGLKEGCRSLSGTSVASPVVAGAVTLLASTV--LNREL---VNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVEKPIWQPYLPQNGDYVDVAVSYSPVLWPWAGYLAVSISVAKKAASWEGIAQGHVMVTVASPAENDSAIGGEMTSTVKLPVKVKIVPTPPRSKRILWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPITCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNDLISVWGMAFSDGLYEGDFTLADHDMYYASGCSIARFPEDG-----IVIAQTLKDQGLEVLKQETAVVENVPVLGLYQTP---SDGGGRIALYGDSNCIDDSHRQKDCFWLLDALLQYTSYSMTPPSLTHSKNRLVPPTGTDRPLPQRLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSVDMDKVVLPNVRAYRPQV 987
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Zebrafish
Match: mbtps1 (membrane-bound transcription factor peptidase, site 1 [Source:ZFIN;Acc:ZDB-GENE-030131-4909])

HSP 1 Score: 513.072 bits (1320), Expect = 1.086e-168
Identity = 280/611 (45.83%), Postives = 396/611 (64.81%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS---KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGRVKPD+VTYG+ +  + L   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P++     +NGD + V+V++S  LWPW GYLA+ I+V  + + W+GIA+G+++  V S    +SA    +T+ +K+P+K K++PTP R  RILWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LG+   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLIVF++WYN  VM  ++F+DENTR WW PDTGGAN+PALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP        ++ A+ LKD G E+LK  +  V +  +LGLY  P   S   GRI++YGDSNC+D + R KDC WLLD+LLQY+        L+   + +    G ++  P+R + + L+++S V+++  G+    + LP C               PSN         + +D   +P+   YRPQ+
Sbjct:  394 ELPGGYGRVKPDIVTYGSGVRGSGLKEGCRSLSGTSVASPVVAGAVTLLASTV--LNREL---VNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVEKPIWQPYLPQNGDYVDVAVSYSPVLWPWAGYLAVSISVAKKAASWEGIAQGHVMVTVASPAENDSAIGGEMTSTVKLPVKVKIVPTPPRSKRILWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPITCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNDLISVWGMAFSDGLYEGDFTLADHDMYYASGCSIARFPEDG-----IVIAQTLKDQGLEVLKQETAVVENVPVLGLYQTP---SDGGGRIALYGDSNCIDDSHRQKDCFWLLDALLQYTSYSMTPPSLTHSKNRLVPPTGTDRPLPQRLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSVDMDKVVLPNVRAYRPQV 987
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Zebrafish
Match: mbtps1 (membrane-bound transcription factor peptidase, site 1 [Source:ZFIN;Acc:ZDB-GENE-030131-4909])

HSP 1 Score: 389.423 bits (999), Expect = 2.389e-122
Identity = 193/440 (43.86%), Postives = 282/440 (64.09%), Query Frame = 1 
Query:  559 DKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS---KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            D + V+V++S  LWPW GYLA+ I+V  + + W+GIA+G+++  V S    +SA    +T+ +K+P+K K++PTP R  RILWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LG+   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLIVF++WYN  VM  ++F+DENTR WW PDTGGAN+PALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP        ++ A+ LKD G E+LK  +  V +  +LGLY  P   S   GRI++YGDSNC+D + R KDC WLLD+LLQY+        L+   + +    G ++  P+R + + L+++S V+++  G+    + LP C               PSN         + +D   +P+   YRPQ+
Sbjct:  465 DYVDVAVSYSPVLWPWAGYLAVSISVAKKAASWEGIAQGHVMVTVASPAENDSAIGGEMTSTVKLPVKVKIVPTPPRSKRILWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPITCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNDLISVWGMAFSDGLYEGDFTLADHDMYYASGCSIARFPEDG-----IVIAQTLKDQGLEVLKQETAVVENVPVLGLYQTP---SDGGGRIALYGDSNCIDDSHRQKDCFWLLDALLQYTSYSMTPPSLTHSKNRLVPPTGTDRPLPQRLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSVDMDKVVLPNVRAYRPQV 894
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Xenopus
Match: inppl1 (inositol polyphosphate phosphatase like 1 [Source:Xenbase;Acc:XB-GENE-1013837])

HSP 1 Score: 513.072 bits (1320), Expect = 1.336e-168
Identity = 277/566 (48.94%), Postives = 375/566 (66.25%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLT---TNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC 1731
            E+P GYGR+KPD+VTYG+ +  + L G C+++SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ A++ L   +PQAS  PSYVDLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P +      NGD I V+ ++S  LWPW+GYLA+ I+V  + S W+GIA+G+I+  V S      KN     + +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF++S YGTL++VD EEEFF  E  KL +DV  NGLSL+VF++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +GD  + N  + Y SG  I+ FP     IS     + LKD G E+LK  ++ V++  +LG+Y  P   S   GRI +YGDSNCLD + R KDC WL+D+LLQY+  G +   LS   +  K   G    PP+R + + L ++S V+++  G+    + LP C
Sbjct:  388 ELPGGYGRMKPDIVTYGSGVRGSGLKGGCRSLSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAFQILNSYKPQASLSPSYVDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPDWQPYLPHNGDNIEVAFSYSSVLWPWSGYLAISISVAKKASSWEGIAQGHIMVTVASPEENESKNGAEQFSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLLVDSEEEFFPEEISKLRRDVA-NGLSLVVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNDLLSVWSMSFSDGIYEGDFTMANHDMYYASGCSIAMFPEEGAVIS-----QSLKDQGLEVLKQETSLVQNVPVLGMYQTP---SEGGGRIVLYGDSNCLDDSHRQKDCFWLMDALLQYTSYGVMPPSLSHSENRQKPPSGEGITPPERLEGNHLHRYSKVLETHLGDPKP-RPLPNC 936
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Xenopus
Match: inppl1 (inositol polyphosphate phosphatase like 1 [Source:Xenbase;Acc:XB-GENE-1013837])

HSP 1 Score: 510.76 bits (1314), Expect = 9.588e-168
Identity = 278/569 (48.86%), Postives = 376/569 (66.08%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLT---TNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKN---KIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC 1731
            E+P GYGR+KPD+VTYG+ +  + L G C+++SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ A++ L   +PQAS  PSYVDLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P +      NGD I V+ ++S  LWPW+GYLA+ I+V  + S W+GIA+G+I+  V S      KN     + +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF++S YGTL++VD EEEFF  E  KL +DV  NGLSL+VF++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +GD  + N   K + Y SG  I+ FP     IS     + LKD G E+LK  ++ V++  +LG+Y  P   S   GRI +YGDSNCLD + R KDC WL+D+LLQY+  G +   LS   +  K   G    PP+R + + L ++S V+++  G+    + LP C
Sbjct:  384 ELPGGYGRMKPDIVTYGSGVRGSGLKGGCRSLSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAFQILNSYKPQASLSPSYVDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPDWQPYLPHNGDNIEVAFSYSSVLWPWSGYLAISISVAKKASSWEGIAQGHIMVTVASPEENESKNGAEQFSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLLVDSEEEFFPEEISKLRRDVA-NGLSLVVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNDLLSVWSMSFSDGIYEGDFTMANHDSKCMYYASGCSIAMFPEEGAVIS-----QSLKDQGLEVLKQETSLVQNVPVLGMYQTP---SEGGGRIVLYGDSNCLDDSHRQKDCFWLMDALLQYTSYGVMPPSLSHSENRQKPPSGEGITPPERLEGNHLHRYSKVLETHLGDPKP-RPLPNC 935
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Xenopus
Match: inppl1 (inositol polyphosphate phosphatase like 1 [Source:Xenbase;Acc:XB-GENE-1013837])

HSP 1 Score: 436.417 bits (1121), Expect = 9.902e-140
Identity = 234/457 (51.20%), Postives = 310/457 (67.83%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLT---TNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRV 1404
            E+P GYGR+KPD+VTYG+ +  + L G C+++SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ A++ L   +PQAS  PSYVDLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P +      NGD I V+ ++S  LWPW+GYLA+ I+V  + S W+GIA+G+I+  V S      KN     + +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF++S YGTL++VD EEEFF  E  KL +DV  NGLSL+VF++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +GD  + N  + Y SG  I+ FP     IS+ L  +    L D LL+  S  V
Sbjct:  388 ELPGGYGRMKPDIVTYGSGVRGSGLKGGCRSLSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAFQILNSYKPQASLSPSYVDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPDWQPYLPHNGDNIEVAFSYSSVLWPWSGYLAISISVAKKASSWEGIAQGHIMVTVASPEENESKNGAEQFSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLLVDSEEEFFPEEISKLRRDVA-NGLSLVVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNDLLSVWSMSFSDGIYEGDFTMANHDMYYASGCSIAMFPEEGAVISQSLKDQDCFWLMDALLQYTSYGV 836
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Xenopus
Match: inppl1 (inositol polyphosphate phosphatase like 1 [Source:Xenbase;Acc:XB-GENE-1013837])

HSP 1 Score: 394.045 bits (1011), Expect = 2.979e-124
Identity = 192/395 (48.61%), Postives = 265/395 (67.09%), Query Frame = 1 
Query:  559 DKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLT---TNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC 1731
            DK++V+ ++S  LWPW+GYLA+ I+V  + S W+GIA+G+I+  V S      KN     + +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF++S YGTL++VD EEEFF  E  KL +DV  NGLSL+VF++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +GD  + N  + Y SG  I+ FP     IS     + LKD G E+LK  ++ V++  +LG+Y  P   S   GRI +YGDSNCLD + R KDC WL+D+LLQY+  G +   LS   +  K   G    PP+R + + L ++S V+++  G+    + LP C
Sbjct:  441 DKVKVAFSYSSVLWPWSGYLAISISVAKKASSWEGIAQGHIMVTVASPEENESKNGAEQFSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLLVDSEEEFFPEEISKLRRDVA-NGLSLVVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNDLLSVWSMSFSDGIYEGDFTMANHDMYYASGCSIAMFPEEGAVIS-----QSLKDQGLEVLKQETSLVQNVPVLGMYQTP---SEGGGRIVLYGDSNCLDDSHRQKDCFWLMDALLQYTSYGVMPPSLSHSENRQKPPSGEGITPPERLEGNHLHRYSKVLETHLGDPKP-RPLPNC 825
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Xenopus
Match: inppl1 (inositol polyphosphate phosphatase like 1 [Source:Xenbase;Acc:XB-GENE-1013837])

HSP 1 Score: 347.051 bits (889), Expect = 4.168e-106
Identity = 181/392 (46.17%), Postives = 248/392 (63.27%), Query Frame = 1 
Query:  571 VSVTHSQFLWPWTG----YLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC 1731
            V +T   ++WP+      Y  +   V        G+  G IV   +SKN A      + +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF++S YGTL++VD EEEFF  E  KL +DV  NGLSL+VF++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +GD  + N  + Y SG  I+ FP     IS     + LKD G E+LK  ++ V++  +LG+Y  P   S   GRI +YGDSNCLD + R KDC WL+D+LLQY+  G +   LS   +  K   G    PP+R + + L ++S V+++  G+    + LP C
Sbjct:  498 VDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVT-GRIVD--KSKNGAEQ---FSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLLVDSEEEFFPEEISKLRRDVA-NGLSLVVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNDLLSVWSMSFSDGIYEGDFTMANHDMYYASGCSIAMFPEEGAVIS-----QSLKDQGLEVLKQETSLVQNVPVLGMYQTP---SEGGGRIVLYGDSNCLDDSHRQKDCFWLMDALLQYTSYGVMPPSLSHSENRQKPPSGEGITPPERLEGNHLHRYSKVLETHLGDPKP-RPLPNC 873

HSP 2 Score: 125.176 bits (313), Expect = 5.456e-29
Identity = 82/155 (52.90%), Postives = 108/155 (69.68%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSG 510
            E+P GYGR+KPD+VTYG+ +  + L G C+++SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ A++ L   +PQAS  PSYVDLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G
Sbjct:  388 ELPGGYGRMKPDIVTYGSGVRGSGLKGGCRSLSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAFQILNSYKPQASLSPSYVDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTG 535
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Mouse
Match: Mbtps1 (membrane-bound transcription factor peptidase, site 1 [Source:MGI Symbol;Acc:MGI:1927235])

HSP 1 Score: 504.982 bits (1299), Expect = 9.536e-166
Identity = 272/566 (48.06%), Postives = 374/566 (66.08%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSA---NDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC 1731
            E+P GYGRVKPD+VTYG  +  + + G C+ +SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P +     +NGD I V+ ++S  LWPW+GYLA+ I+V  + + W+GIA+G+I+  V S       +    T+ +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF+++ YGTL++VD EEE+F  E  KL +DV +NGLSL++F++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +G+  + N  + Y SG  I++FP     I+     +  KD G E+LK  +  V +  ILGLY   +I S   GRI +YGDSNCLD + R KDC WLLD+LLQY+  G     LS   +  +   GA   PP+R + + L ++S V+++  G+    + LP C
Sbjct:  379 ELPGGYGRVKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASVKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHIMITVASPAETELHSGAEHTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDATQYGTLLLVDSEEEYFPEEIAKLRRDV-DNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFVLANHDMYYASGCSIAKFPEDGVVIT-----QTFKDQGLEVLKQETAVVENVPILGLY---QIPSEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEAHLGDPKP-RPLPAC 927
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Mouse
Match: Mbtps1 (membrane-bound transcription factor peptidase, site 1 [Source:MGI Symbol;Acc:MGI:1927235])

HSP 1 Score: 504.982 bits (1299), Expect = 9.536e-166
Identity = 272/566 (48.06%), Postives = 374/566 (66.08%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSA---NDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC 1731
            E+P GYGRVKPD+VTYG  +  + + G C+ +SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P +     +NGD I V+ ++S  LWPW+GYLA+ I+V  + + W+GIA+G+I+  V S       +    T+ +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF+++ YGTL++VD EEE+F  E  KL +DV +NGLSL++F++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +G+  + N  + Y SG  I++FP     I+     +  KD G E+LK  +  V +  ILGLY   +I S   GRI +YGDSNCLD + R KDC WLLD+LLQY+  G     LS   +  +   GA   PP+R + + L ++S V+++  G+    + LP C
Sbjct:  379 ELPGGYGRVKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASVKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHIMITVASPAETELHSGAEHTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDATQYGTLLLVDSEEEYFPEEIAKLRRDV-DNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFVLANHDMYYASGCSIAKFPEDGVVIT-----QTFKDQGLEVLKQETAVVENVPILGLY---QIPSEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEAHLGDPKP-RPLPAC 927
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. UniProt/SwissProt
Match: sp|Q9WTZ3|MBTP1_RAT (Membrane-bound transcription factor site-1 protease OS=Rattus norvegicus OX=10116 GN=Mbtps1 PE=1 SV=2)

HSP 1 Score: 507.679 bits (1306), Expect = 5.549e-166
Identity = 274/566 (48.41%), Postives = 375/566 (66.25%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKN---LTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC 1731
            E+P GYGRVKPD+VTYG  +  + + G C+ +SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P +     +NGD I V+ ++S  LWPW+GYLA+ I+V  + + W+GIA+G+I+  V S      KN    T+ +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF+++ YGTL++VD EEE+F  E  KL +DV +NGLSL+VF++WYN  VM  ++F+DENTR WW PDTGGAN+PALN LL+ + + FSD + +G+  + N  + Y SG  I+RFP     I+     +  KD G E+LK  +  V +  ILGLY   +I +   GRI +YGDSNCLD + R KDC WLLD+LLQY+  G     LS   +  +   GA   PP+R + + L ++S V+++  G+    + LP C
Sbjct:  379 ELPGGYGRVKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASVKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHIMITVASPAETELKNGAEHTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDATQYGTLLMVDSEEEYFPEEIAKLRRDV-DNGLSLVVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNELLSVWNMGFSDGLYEGEFALANHDMYYASGCSIARFPEDGVVIT-----QTFKDQGLEVLKQETAVVDNVPILGLY---QIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEAHLGDPKP-RPLPAC 927
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. UniProt/SwissProt
Match: sp|Q9Z2A8|MBTP1_CRIGR (Membrane-bound transcription factor site-1 protease OS=Cricetulus griseus OX=10029 GN=MBTPS1 PE=1 SV=2)

HSP 1 Score: 507.679 bits (1306), Expect = 6.582e-166
Identity = 273/566 (48.23%), Postives = 375/566 (66.25%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKN---LTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC 1731
            E+P GYGRVKPD+VTYG  +  + + G C+ +SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P +     +NGD I V+ ++S  LWPW+GYLA+ I+V  + + W+GIA+G+I+  V S      KN    T+ +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF+++ YGTL++VD EEE+F  E  KL +DV +NGLSL++F++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +G+  + N  + Y SG  I++FP     I+     +  KD G E+LK  +  V +  ILGLY   +I +   GRI +YGDSNCLD + R KDC WLLD+LLQY+  G     LS   +  +   GA   PP+R + + L ++S V+++  G+    + LP C
Sbjct:  379 ELPGGYGRVKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASVKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHIMITVASPAETEAKNGAEHTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDATQYGTLLMVDSEEEYFPEEIAKLRRDV-DNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFALANHDMYYASGCSIAKFPEDGVVIT-----QTFKDQGLEVLKQETAVVENVPILGLY---QIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEAHLGDPKP-RPLPAC 927
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. UniProt/SwissProt
Match: sp|Q14703|MBTP1_HUMAN (Membrane-bound transcription factor site-1 protease OS=Homo sapiens OX=9606 GN=MBTPS1 PE=1 SV=1)

HSP 1 Score: 506.908 bits (1304), Expect = 1.159e-165
Identity = 280/611 (45.83%), Postives = 389/611 (63.67%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKN---LTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLCRR-------------PSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGR+KPD+VTYG  +  + + G C+ +SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  PSY+DLTE PYMWPY SQP+Y   MP ++N+TI+N M V+G     P +     +NGD I V+ ++S  LWPW+GYLA+ I+V  + + W+GIA+G+++  V S      KN    T+ +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LG+ F CF++S YGTL++VD EEE+F  E  KL +DV +NGLSL++F++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +G+  + N  + Y SG  I++FP     I+     +  KD G E+LK  +  V +  ILGLY   +I +   GRI +YGDSNCLD + R KDC WLLD+LLQY+  G     LS   +  +   GA    P+R + + L ++S V+++  G+    + LP C R             PSN         + +D   +P+  + RPQ+
Sbjct:  379 ELPGGYGRMKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAEQTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDV-DNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTLANHDMYYASGCSIAKFPEDGVVIT-----QTFKDQGLEVLKQETAVVENVPILGLY---QIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKP-RPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQV 972
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. UniProt/SwissProt
Match: sp|Q9WTZ2|MBTP1_MOUSE (Membrane-bound transcription factor site-1 protease OS=Mus musculus OX=10090 GN=Mbtps1 PE=1 SV=1)

HSP 1 Score: 504.982 bits (1299), Expect = 6.671e-165
Identity = 272/566 (48.06%), Postives = 374/566 (66.08%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSA---NDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC 1731
            E+P GYGRVKPD+VTYG  +  + + G C+ +SGTSVASP VA AV LL+              +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P +     +NGD I V+ ++S  LWPW+GYLA+ I+V  + + W+GIA+G+I+  V S       +    T+ +K+PIK K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+ F CF+++ YGTL++VD EEE+F  E  KL +DV +NGLSL++F++WYN  VM  ++F+DENTR WW PDTGGANIPALN LL+ + + FSD + +G+  + N  + Y SG  I++FP     I+     +  KD G E+LK  +  V +  ILGLY   +I S   GRI +YGDSNCLD + R KDC WLLD+LLQY+  G     LS   +  +   GA   PP+R + + L ++S V+++  G+    + LP C
Sbjct:  379 ELPGGYGRVKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQK-----RELVNPASVKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHIMITVASPAETELHSGAEHTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDATQYGTLLLVDSEEEYFPEEIAKLRRDV-DNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFVLANHDMYYASGCSIAKFPEDGVVIT-----QTFKDQGLEVLKQETAVVENVPILGLY---QIPSEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEAHLGDPKP-RPLPAC 927
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. UniProt/SwissProt
Match: sp|Q0WUG6|SBT61_ARATH (Subtilisin-like protease SBT6.1 OS=Arabidopsis thaliana OX=3702 GN=SBT6.1 PE=1 SV=1)

HSP 1 Score: 410.994 bits (1055), Expect = 3.526e-129
Identity = 234/515 (45.44%), Postives = 322/515 (62.52%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKN-LTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPL 1584
            E+P GYGRVKPDVV YG  I+ + +   CK++SGTSVASP VA  V LL+              +PAS+KQA++ GA +L  S  N++EQG G+++L+ +Y  L    P+AS +PS +D  + PY WP+  QPLY+ AMPII N TI+N M V G    PP +H  ++  G+ + +   +   +WPWTGYLAL + + +E +++ G  EG +   V S  ++ +     +   + +K KVIPTP R  RILWDQFH+++YPPGYIPRD++  R + LDW GDH+HTNF   Y+ LR+  Y+IE LGS   CF++  YGTL++VD E+++F  E  KL  DV   GL L+VFAEWYNV  M  +RFFD+NTR WWTP TGGANIPALN LLA FGI F D++L+GD  I  +  +Y SGT I RFP      +  L           LL   +++  D A+LGL     ++ G  GR+ VYGDSNCLD +    +C WLL  +L +S + +I +P+
Sbjct:  374 ELPHGYGRVKPDVVAYGRDIMGSKISTGCKSLSGTSVASPVVAGIVCLLVSVIP--EARRKDLLNPASMKQALVEGAAKL--SGPNMYEQGAGRVDLLESYEILKSYHPRASIFPSILDYNDCPYSWPFCRQPLYAGAMPIIFNTTILNGMGVIGYIESPPTWHP-ANEEGNLLSIHFKYPDVIWPWTGYLALHMQIKEEGAQFTGEIEGNVTVKVYSPPASGESGPRRSTCSLQLKLKVIPTPPRAKRILWDQFHSIKYPPGYIPRDSLDVRNDILDWHGDHLHTNFHIMYNMLRDAGYYIETLGSPLTCFDAQQYGTLLMVDLEDDYFPEEIEKLRDDVINTGLGLVVFAEWYNVDTMVKMRFFDDNTRSWWTPVTGGANIPALNNLLASFGIAFGDKILNGDFSIDGEQSRYASGTNIVRFPAGGFLHTFPLLDSSESGATQNLLLTEASK-EDPAVLGL-----LEIG-EGRVGVYGDSNCLDSSHMVTNCYWLLKKMLDFSSS-NIKDPV 875
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. TrEMBL
Match: A0A3Q4BVM7 (Membrane-bound transcription factor peptidase, site 1 OS=Mola mola OX=94237 PE=4 SV=1)

HSP 1 Score: 525.783 bits (1353), Expect = 2.866e-170
Identity = 287/610 (47.05%), Postives = 396/610 (64.92%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSAND--KNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P+GYGRVKPD+VTYG+ +  + +   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+LI AY+ L    PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P++     +NGD I V+V+HS  LWPW+GYLA+ I+V  + + W+GIA+G+++  V S  + ND    LT+ +K+PIK K++PTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LG+   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLI+F++WYN  VM  ++F+DENTR WW PDTGGAN+PALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP        ++ AK+LKD G E+LK  +  V    ILGLY  P   S   GRI +YGDSNC+D + R KDC WLLD+LLQY+        LS   S V +  G  +  P+R + + L+++S V+++  G+    + LP C               PSN         + +D  ++P    YRPQ+
Sbjct:  391 ELPWGYGRVKPDIVTYGSGVRGSGMKEGCRSLSGTSVASPVVAGAVTLLASTV--LNREL---VNPASMKQALIASARRLPG--VNMFEQGHGKLDLIRAYQILNSYRPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPIWQPYLPQNGDHIDVAVSHSPVLWPWSGYLAVSISVAKKAASWEGIAQGHVIVTVASP-AENDVGSELTSTVKLPIKVKIVPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPLTCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNDLISVWGMAFSDGLYEGDFTLADHDMYYASGCSIARFPEDG-----IVIAKKLKDQGLEVLKQETAVVEGVPILGLYQTP---SDGGGRIVLYGDSNCIDDSHRQKDCFWLLDALLQYTSYSMTPSSLSHSHSRVAAPTGNERLLPQRLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPVNETAPSNLWKHQKLLSVDLDKVALPHAKVYRPQV 982
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. TrEMBL
Match: A0A3P9MUD8 (Membrane-bound transcription factor peptidase, site 1 OS=Poecilia reticulata OX=8081 PE=4 SV=1)

HSP 1 Score: 520.39 bits (1339), Expect = 1.806e-169
Identity = 286/611 (46.81%), Postives = 395/611 (64.65%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS---KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGRVKPD+VTYG+ +  + L   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+LI AY+ L    PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P++     +NGD I V+V++S  LWPW GYLA+ I+V  + + W+GIA+G+++  V S    +S     LT+ +K+PIK K++PTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDH+HTNF+D Y +LR+  YF+E+LG+   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLI+F++WYN  VM  ++F+DENTR WW PDTGGAN+PALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP        ++ AK LKD G E+LK  +  V    ILGLY  P   S   GRI +YGDSNC+D + R KDC WLLD+LLQY+        LS   S V   +GA +  P+R + + L+++S V+++  G+    + LP C               PSN         + +D  ++P+  +YRPQ+
Sbjct:  280 ELPGGYGRVKPDIVTYGSGVRGSGLKEGCRSLSGTSVASPVVAGAVTLLASTV--LNREL---VNPASMKQALIASARRLPG--VNMFEQGHGKLDLIRAYQILNSYRPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPIWQPYLPQNGDNIDVAVSYSPVLWPWAGYLAVSISVAKKAASWEGIAQGHVMVTVASPAENDSEVGGELTSTVKLPIKVKIVPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPLTCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNDLISVWGMAFSDGLYEGDFTLADHDMYYASGCSIARFPEDG-----IVIAKNLKDQGLEVLKQETAVVEGVPILGLYQTP---SEGGGRIVLYGDSNCIDDSHRQKDCFWLLDALLQYTSYSMTPPSLSHSHSRVAPPVGAERPLPQRLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSVDLDKVALPNMKSYRPQV 873
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. TrEMBL
Match: G3NFI3 (Membrane-bound transcription factor peptidase, site 1 OS=Gasterosteus aculeatus OX=69293 PE=4 SV=1)

HSP 1 Score: 521.931 bits (1343), Expect = 2.482e-169
Identity = 286/611 (46.81%), Postives = 396/611 (64.81%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS---KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGRVKPD+VTYG+ +  + +   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+LI AY+ L   +PQAS  PSY+DLTE+PYMWPY SQP+Y   MP I+N+TI+N M V+G     PV+     +NGD + V+V+++  LWPW GYLA+ I+V  + + W+G+A+G+++  V S    +S     LT+ +K+PIK K++PTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNFKD Y +LR+  YF+E+LG+   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLIVF++WYN  VM  ++F+DENTR WW PDTGGAN+PALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP        ++ AK LKD G E+LK  +  V    ILGLY  P   S   GRI++YGDSNC+D + R KDC WLLD+LLQY+        LS   S V    GA +  P+R + + L+++S V+++  G+    + LP C               PSN         + +D  ++P+   YRPQ+
Sbjct:  343 ELPGGYGRVKPDIVTYGSGVRGSGMKEGCRSLSGTSVASPVVAGAVTLLASTV--LNREL---VNPASMKQALIASARRLPG--VNMFEQGHGKLDLIRAYQILNSYKPQASLSPSYIDLTESPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPVWQPYLPQNGDHVDVAVSYAPVLWPWAGYLAVSISVAKKAASWEGVAQGHVMVTVASPAENDSEAGGELTSTVKLPIKVKIVPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFKDMYQHLRSMGYFVEVLGAPITCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNDLISVWGMAFSDGLYEGDFTLADHDMYYASGCSIARFPEDG-----IVIAKNLKDQGLEVLKQETAVVEGVPILGLYQTP---SDGGGRIALYGDSNCIDDSHRQKDCFWLLDALLQYTSYSMTPPSLSHSHSRVAPPTGAERPLPQRLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSVDLDKVALPNMRAYRPQV 936
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. TrEMBL
Match: A0A3Q1GFJ6 (Membrane-bound transcription factor peptidase, site 1 OS=Acanthochromis polyacanthus OX=80966 PE=4 SV=1)

HSP 1 Score: 521.931 bits (1343), Expect = 2.500e-169
Identity = 288/611 (47.14%), Postives = 395/611 (64.65%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS---KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGRVKPD+VTYG+ +  + +   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+LI AY+ L    PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P++     +NGD I V+V++S  LWPW GYLA+ I+V  + + W+GIA+G+++  V S    +S     LT+ +K+PIK K++PTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LG+   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLIVF++WYN  VM  ++F+DENTR WW PDTGGAN+PALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP        ++ AK LKD G E+LK  +T V    ILGLY  P   S   GRI++YGDSNC+D + R KDC WLLD+LLQY+        LS   S V    GA +  P+R + + L+++S V+++  G+    + LP C               PSN         + +D  ++P+   YRPQ+
Sbjct:  403 ELPGGYGRVKPDIVTYGSGVRGSGMKEGCRSLSGTSVASPVVAGAVTLLASTV--LNREL---VNPASMKQALIASARRLPG--VNMFEQGHGKLDLIRAYQILNSYRPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPIWQPYLPQNGDHIDVAVSYSPVLWPWAGYLAVSISVAKKAASWEGIAQGHVMVTVASPAENDSEVGGELTSTVKLPIKVKIVPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPITCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNDLISVWGMAFSDGLYEGDFTLADHDMYYASGCSIARFPEDG-----IVIAKNLKDQGLEVLKQETTVVEGVPILGLYQTP---SDGGGRIALYGDSNCIDDSHRQKDCFWLLDALLQYTSYSMTPPSLSHSHSRVAPPTGAERPLPQRLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPVNETAPSNLWKHQKLLSVDLDKVALPNVRAYRPQV 996
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. TrEMBL
Match: A0A1S3HYQ9 (membrane-bound transcription factor site-1 protease-like OS=Lingula unguis OX=7574 GN=LOC106159410 PE=4 SV=1)

HSP 1 Score: 521.546 bits (1342), Expect = 3.688e-169
Identity = 285/600 (47.50%), Postives = 394/600 (65.67%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNL-TTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLCRRPSNTEMRIDNFSIPDESTYRPQLLIKKKEYNVPL 1839
            E+PFGYGR+KPD+VTYG+Q+  +++ G C+++SGTSVASP VA AV LL  A       ++    PAS+KQA+++ A RL  S  N+FEQG GKL+L+ AY+ L   +PQAS  PSYVDLTE PYMWPY +QP+Y  AMP+I+N+TI+N M VSG     P++   + + G+ I V+ ++   LWPW+GYLA+ I+V    + W GIA+G +   V S     +K+  T+ +K+PIKAK+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LRN  Y++E+LGS F CF++S YGTL+IVD EEE+F  E  KL +D+ +NGLSLI+FA+WYN+ VM  ++F+DENTR WW PDTGGANIPA+N LL+P G+ FSD+V +G+  +    + Y SGT I++FP        LL  + LKD G E++KG S       ILGL+ G        GR+++YGDSNCLD +   KDC WLL +LL+++  G I    +   +  K+ L  N   P+R + + L ++S V+++  G Q + + LP C           N S P       +LL    + N+PL
Sbjct:  353 ELPFGYGRMKPDIVTYGSQVRGSAMRGGCRSLSGTSVASPVVAGAVTLLYSAVLNRAHVVN----PASMKQALMASAKRLPGS--NMFEQGHGKLDLVKAYQVLRSYKPQASLSPSYVDLTECPYMWPYCTQPMYYGAMPVIVNVTILNGMGVSGKILEKPLWQPYTPQFGNYIEVAFSYPTELWPWSGYLAVSISVSKGAANWDGIAQGLVTLTVTSPPEDGEKSARTSTIKLPIKAKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYTHLRNSGYYVEVLGSPFTCFDASQYGTLLIVDAEEEYFPGEVTKLKQDI-DNGLSLIIFADWYNISVMKKVKFYDENTRQWWMPDTGGANIPAINDLLSPLGMAFSDEVYEGEFTLGEHEMYYASGTSIAKFPEDG-----LLITQSLKDQGYEVVKGESITADKVPILGLHEGK--SPSRQGRVALYGDSNCLDNSHIQKDCYWLLSALLEFTAHGQIPPSFTEKKADHKTILLKNDL-PERMEGNHLHRYSKVLENHLGAQRS-RPLPACPHLVWAAPSPLNTSAPSNLVQHQKLLSISYDVNLPL 936
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Cavefish
Match: mbtps1 (membrane bound transcription factor peptidase, site 1 [Source:NCBI gene;Acc:103032608])

HSP 1 Score: 514.612 bits (1324), Expect = 3.214e-170
Identity = 283/610 (46.39%), Postives = 393/610 (64.43%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS--KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGRVKPD+VTYG+ +  + +   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L    PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P++     +NGD I V+V++S  LWPW GYL + I+V  + + W+GIA+G+++  V S  +N ++   +T+ +K+P+K K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LGS   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLI+F++WYN  VM  ++F+DENTR WW PDTGGANIPALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP     I     A+ LKD G E+LK  +  V    +LGLY  P   S   GRI++YGDSNC+D + R KDC WLLD+LLQY+  G     L    + V    G +K  P+R + + L+++S V+++  G+    + LP C               PSN         + +D   +P+   YRPQ+
Sbjct:  319 ELPGGYGRVKPDIVTYGSGVRGSGMKEGCRSLSGTSVASPVVAGAVTLLASTV--LNREL---VNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILNSYRPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPIWQPYLPQNGDHIDVAVSYSPVLWPWAGYLGVSISVAKKAASWEGIAQGHVMLTVASPAENDSSVGEMTSTVKLPVKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGSPITCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNDLISVWGMAFSDGLYEGDFTMADHDMYYASGCSIARFPEDGVVI-----AQTLKDQGLEVLKQETAVVDSVPVLGLYQTP---SEGGGRIALYGDSNCIDDSHRQKDCFWLLDALLQYTSYGVTPPSLLHSQNKVTPPTGTDKPLPERLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSVDMDKVELPNVRAYRPQV 911
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Cavefish
Match: mbtps1 (membrane bound transcription factor peptidase, site 1 [Source:NCBI gene;Acc:103032608])

HSP 1 Score: 514.612 bits (1324), Expect = 5.383e-170
Identity = 283/610 (46.39%), Postives = 393/610 (64.43%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS--KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGRVKPD+VTYG+ +  + +   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L    PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P++     +NGD I V+V++S  LWPW GYL + I+V  + + W+GIA+G+++  V S  +N ++   +T+ +K+P+K K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LGS   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLI+F++WYN  VM  ++F+DENTR WW PDTGGANIPALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP     I     A+ LKD G E+LK  +  V    +LGLY  P   S   GRI++YGDSNC+D + R KDC WLLD+LLQY+  G     L    + V    G +K  P+R + + L+++S V+++  G+    + LP C               PSN         + +D   +P+   YRPQ+
Sbjct:  339 ELPGGYGRVKPDIVTYGSGVRGSGMKEGCRSLSGTSVASPVVAGAVTLLASTV--LNREL---VNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILNSYRPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPIWQPYLPQNGDHIDVAVSYSPVLWPWAGYLGVSISVAKKAASWEGIAQGHVMLTVASPAENDSSVGEMTSTVKLPVKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGSPITCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNDLISVWGMAFSDGLYEGDFTMADHDMYYASGCSIARFPEDGVVI-----AQTLKDQGLEVLKQETAVVDSVPVLGLYQTP---SEGGGRIALYGDSNCIDDSHRQKDCFWLLDALLQYTSYGVTPPSLLHSQNKVTPPTGTDKPLPERLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSVDMDKVELPNVRAYRPQV 931
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Cavefish
Match: mbtps1 (membrane bound transcription factor peptidase, site 1 [Source:NCBI gene;Acc:103032608])

HSP 1 Score: 514.998 bits (1325), Expect = 2.140e-169
Identity = 283/610 (46.39%), Postives = 393/610 (64.43%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS--KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGRVKPD+VTYG+ +  + +   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L    PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P++     +NGD I V+V++S  LWPW GYL + I+V  + + W+GIA+G+++  V S  +N ++   +T+ +K+P+K K+IPTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LGS   CF++S YGTL++VD EEE+F  E  KL +D+ +NGLSLI+F++WYN  VM  ++F+DENTR WW PDTGGANIPALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP     I     A+ LKD G E+LK  +  V    +LGLY  P   S   GRI++YGDSNC+D + R KDC WLLD+LLQY+  G     L    + V    G +K  P+R + + L+++S V+++  G+    + LP C               PSN         + +D   +P+   YRPQ+
Sbjct:  405 ELPGGYGRVKPDIVTYGSGVRGSGMKEGCRSLSGTSVASPVVAGAVTLLASTV--LNREL---VNPASMKQALIASARRLPG--VNMFEQGHGKLDLLRAYQILNSYRPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPIWQPYLPQNGDHIDVAVSYSPVLWPWAGYLGVSISVAKKAASWEGIAQGHVMLTVASPAENDSSVGEMTSTVKLPVKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGSPITCFDASQYGTLLMVDSEEEYFPEEITKLRRDI-DNGLSLIIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNDLISVWGMAFSDGLYEGDFTMADHDMYYASGCSIARFPEDGVVI-----AQTLKDQGLEVLKQETAVVDSVPVLGLYQTP---SEGGGRIALYGDSNCIDDSHRQKDCFWLLDALLQYTSYGVTPPSLLHSQNKVTPPTGTDKPLPERLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSVDMDKVELPNVRAYRPQV 997
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Sea Lamprey
Match: mbtps1 (membrane-bound transcription factor peptidase, site 1 [Source:ZFIN;Acc:ZDB-GENE-030131-4909])

HSP 1 Score: 499.59 bits (1285), Expect = 3.856e-166
Identity = 272/598 (45.48%), Postives = 389/598 (65.05%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS---KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFP-PKRCQNSRLFKFSAVIKSQNGEQLTYKELPLCRRPSNTEMRIDNFSIPDESTYRPQLLIKKKE 1824
            E+P GYGR+KPD+VTYG+ +  + ++G C+++SGTSVASP V  AV LL  +    +       +PAS+KQA+++ A RL     N+FEQG GKL+L+ AY+ L   +PQAS  P+YVDLTE PYMWPY SQP+Y   MP I+N+TI+N M+V+G     PV+     +NGD I V+ ++SQ LWPW+GYLAL I+V  + + W+GIA G++   + S     + +    T+++++P++ KVIPTP R  RILWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LG+   CF++S YGTL++VD EEE+F  E  KL +DV ++GLS+I+ ++WYN  VM  ++F+DENTR WW PDTGGAN+PALN LL P+ + FSD+V +GD  I +  + Y SG+ I+RFP     I+     + LKD G ++L+  +  V    ILGLY   +      GRI +YGDSNCLD + R KDC W+LD+LLQY+    +S   S   +        ++ P P R + + L+++S V+++  G+    + LP C   S  + +  N + P     +P+LL    E
Sbjct:  236 ELPGGYGRMKPDIVTYGSGVRGSGINGGCRSLSGTSVASPVVTGAVTLLASSVQNRD-----IINPASMKQALMASARRLPG--VNMFEQGHGKLDLLRAYQVLNSYKPQASLSPNYVDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMAVTGRIVDKPVWQPYLPQNGDSIEVAFSYSQTLWPWSGYLALSISVAKKAAGWEGIAHGHVSLTIASPANSQAEDSSEQTSSVRLPVRVKVIPTPPRSKRILWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSNGYFLEVLGAPITCFDASQYGTLVLVDSEEEYFPEEVSKLKRDV-DHGLSVIIVSDWYNTSVMQKVKFYDENTRQWWMPDTGGANVPALNDLLTPWNMAFSDRVFEGDFTIGDHEMYYASGSSIARFPKDGIVIT-----QTLKDQGMDVLRQEAYTVEGVPILGLY---QASGDGAGRIVLYGDSNCLDDSHRQKDCFWMLDALLQYTAYDVLSPVFSEANARGAIQQITHEGPLPTRMEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNQTAPSNLWKQPKLLAMDPE 816
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Medaka
Match: mbtps1 (membrane bound transcription factor peptidase, site 1 [Source:NCBI gene;Acc:101164978])

HSP 1 Score: 520.776 bits (1340), Expect = 7.382e-172
Identity = 286/610 (46.89%), Postives = 395/610 (64.75%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQS--KNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIR-RPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLC-------------RRPSN-------TEMRIDNFSIPDESTYRPQL 1806
            E+P GYGRVKPD+VTYG+ +  + L   C+++SGTSVASP VA AV LL       N  L    +PAS+KQA+++ A RL     N+FEQG GKL+LI AY+ L    PQAS  PSY+DLTE PYMWPY SQP+Y   MP I+N+TI+N M V+G     P++     +NGD I V++++S  LWPW GYLA+ I+V  + + W+G+A+G+++  V S  +N ++   LT+ +K+PIK K++PTP R  R+LWDQ+HNLRYPPGY PRDN+R + +PLDW GDHIHTNF+D Y +LR+  YF+E+LG+   CF++S YGTL++VD EEE+F  E  KL +DV +NGLSLIVF++WYN  VM  ++F+DENTR WW PDTGGAN+PALN L++ +G+ FSD + +GD  + +  + Y SG  I+RFP        ++ AK LKD G E+LK  +  V    ILGLY  P   S   GRI +YGDSNC+D + R KDC WLLD+LLQY+        LS   S V    G+    P+R + + L+++S V+++  G+    + LP C               PSN         + +D  ++P+  +YRPQ+
Sbjct:  393 ELPGGYGRVKPDIVTYGSGVRGSGLKEGCRSLSGTSVASPVVAGAVTLLASTV--LNRELV---NPASMKQALIASARRLPG--VNMFEQGHGKLDLIRAYQILNSYRPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIIDKPIWQPYLPQNGDHIDVAISYSPVLWPWAGYLAVSISVAKKAASWEGVAQGHVMVTVASPAENDSDVGELTSTVKLPIKVKIVPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPITCFDASQYGTLLMVDGEEEYFPEEITKLRRDV-DNGLSLIVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNDLISVWGMAFSDGLYEGDFSLADHDMYYASGCSIARFPEDG-----IVIAKNLKDQGLEVLKQETAVVEGVPILGLYQTP---SEGGGRIVLYGDSNCIDDSHRQKDCFWLLDALLQYTSYSMTPPSLSHSHSRVSPPTGSEHPLPQRLEGNHLYRYSKVLEAHLGDPKP-RPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSVDLDKVALPNVKSYRPQV 985
[Close]
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Planmine SMEST
Match: SMESG000010258.1 (SMESG000010258.1)

HSP 1 Score: 1292.33 bits (3343), Expect = 0.000e+0
Identity = 678/679 (99.85%), Postives = 678/679 (99.85%), Query Frame = 1 
Query:   46 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTXXXXXXXXXXXXXXXXXXXXFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPXXXXXXXXXSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIRRPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLCRRPSNTEMRIDNFSIPDESTYRPQLLIKKKEYNVPLGIGFRNYSPYQSVNLDNRHSRVPRIVLQHSEIIGPRLYWLYXXXXXXXXXXXXXXXXRRLRPKFKEIRPILSAAPHLIFRK 2082
            EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTSVASPSVAAAVALLICAANAFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPIIINITIINSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIRRPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLCRRPSNTEMRIDNFSIPDESTYRPQLLIKKKEYNVPLGIGFRNYSP QSVNLDNRHSRVPRIVLQHSEIIGPRLYWLYVICVCSVCCVVICVFCRRLRPKFKEIRPILSAAPHLIFRK
Sbjct:  245 EIPFGYGRVKPDVVTYGNQIVSTSLHGNCKTISGTSVASPSVAAAVALLICAANAFNGPLDAKPSPASIKQAILSGATRLTSSQANIFEQGMGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPIIINITIINSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYLALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLTTNLKIPIKAKVIPTPLRKMRILWDQFHNLRYPPGYIPRDNIRRPEPLDWTGDHIHTNFKDTYDYLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTENGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPFGIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDLGDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDKDCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFKFSAVIKSQNGEQLTYKELPLCRRPSNTEMRIDNFSIPDESTYRPQLLIKKKEYNVPLGIGFRNYSPNQSVNLDNRHSRVPRIVLQHSEIIGPRLYWLYVICVCSVCCVVICVFCRRLRPKFKEIRPILSAAPHLIFRK 923
The following BLAST results are available for this feature:
BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
MBTPS12.413e-16645.83membrane bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
S1P1.270e-12038.77gene:FBgn0037105 transcript:FBtr0078466[more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
mbtps11.086e-16845.83membrane-bound transcription factor peptidase, sit... [more]
mbtps11.086e-16845.83membrane-bound transcription factor peptidase, sit... [more]
mbtps12.389e-12243.86membrane-bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inppl11.336e-16848.94inositol polyphosphate phosphatase like 1 [Source:... [more]
inppl19.588e-16848.86inositol polyphosphate phosphatase like 1 [Source:... [more]
inppl19.902e-14051.20inositol polyphosphate phosphatase like 1 [Source:... [more]
inppl12.979e-12448.61inositol polyphosphate phosphatase like 1 [Source:... [more]
inppl14.168e-10646.17inositol polyphosphate phosphatase like 1 [Source:... [more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Mbtps19.536e-16648.06membrane-bound transcription factor peptidase, sit... [more]
Mbtps19.536e-16648.06membrane-bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9WTZ3|MBTP1_RAT5.549e-16648.41Membrane-bound transcription factor site-1 proteas... [more]
sp|Q9Z2A8|MBTP1_CRIGR6.582e-16648.23Membrane-bound transcription factor site-1 proteas... [more]
sp|Q14703|MBTP1_HUMAN1.159e-16545.83Membrane-bound transcription factor site-1 proteas... [more]
sp|Q9WTZ2|MBTP1_MOUSE6.671e-16548.06Membrane-bound transcription factor site-1 proteas... [more]
sp|Q0WUG6|SBT61_ARATH3.526e-12945.44Subtilisin-like protease SBT6.1 OS=Arabidopsis tha... [more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3Q4BVM72.866e-17047.05Membrane-bound transcription factor peptidase, sit... [more]
A0A3P9MUD81.806e-16946.81Membrane-bound transcription factor peptidase, sit... [more]
G3NFI32.482e-16946.81Membrane-bound transcription factor peptidase, sit... [more]
A0A3Q1GFJ62.500e-16947.14Membrane-bound transcription factor peptidase, sit... [more]
A0A1S3HYQ93.688e-16947.50membrane-bound transcription factor site-1 proteas... [more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
mbtps13.214e-17046.39membrane bound transcription factor peptidase, sit... [more]
mbtps15.383e-17046.39membrane bound transcription factor peptidase, sit... [more]
mbtps12.140e-16946.39membrane bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mbtps13.856e-16645.48membrane-bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mbtps17.382e-17246.89membrane bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor peptidase, site 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000010258.10.000e+099.85SMESG000010258.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005850 ID=SMED30005850|Name=Membrane-bound transcription factor peptidase, site 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2097bp
CATCTCGGGGCATGACGACATGGAACAAATGAACATGGATAATAGGAAAT
ACCGTTCGGTTACGGACGCGTCAAGCCCGATGTTGTGACTTACGGCAATC
AGATAGTCAGCACGAGTCTCCATGGCAACTGCAAGACGATTTCCGGCACC
AGCGTAGCCAGTCCGTCTGTGGCTGCTGCTGTTGCGCTATTGATTTGCGC
TGCTAATGCATTCAACGGGCCGCTCGATGCCAAGCCCTCTCCTGCCAGTA
TTAAACAGGCCATTCTGTCTGGGGCTACTCGACTCACCAGTTCACAGGCA
AATATATTCGAACAGGGAATGGGAAAGCTCAATCTCATTGCAGCATATCG
AGCGCTGCTTGAATCCGAGCCTCAGGCGAGTGCTTATCCGAGCTATGTCG
ATCTCACTGAGGCCCCTTACATGTGGCCTTATTCCTCACAGCCGCTCTAC
AGCACCGCAATGCCGATAATCATTAATATCACAATTATCAATAGCATGTC
TGTATCTGGAATATTCCCCATTCCCCCGGTATATCACGCCATATCCAGCA
GAAATGGCGATAAAATTCGTGTTTCTGTAACTCATTCACAATTTTTATGG
CCTTGGACTGGATATTTAGCCCTTGAAATTACTGTTCCCGATGAATTTTC
TCGCTGGCAAGGTATCGCCGAGGGATACATTGTAGCAGTTGTTCAATCGA
AAAACTCAGCCAATGATAAGAACCTCACGACGAACCTTAAAATTCCGATT
AAAGCCAAGGTGATCCCAACTCCATTGCGTAAGATGCGAATCCTATGGGA
TCAATTCCATAATTTGCGGTATCCTCCAGGCTACATTCCTCGCGATAACA
TCCGTAGGCCGGAGCCATTAGATTGGACTGGTGATCACATTCATACGAAT
TTCAAAGACACTTATGATTACCTCCGCAATAAGGATTATTTCATTGAAAT
CCTCGGCAGCCATTTCGGTTGTTTTAACTCATCAAACTATGGAACACTAA
TTATCGTCGATCCAGAGGAAGAATTTTTCAATCACGAACAAATGAAATTG
TTTAAAGATGTCACGGAAAATGGACTATCCTTAATAGTCTTTGCCGAGTG
GTACAATGTCAAGGTCATGAATCATCTGAGGTTCTTCGATGAAAATACCA
GAATGTGGTGGACTCCCGATACGGGAGGGGCTAATATTCCAGCCCTGAAT
GGTTTGCTGGCTCCATTTGGGATAGAGTTCAGTGATCAAGTTTTGGACGG
CGACATCAAAATAAAAAATAAAATAATTCAATACAATTCTGGCACTCGAA
TTTCTCGTTTTCCCAATAGCAAAAAATATATTTCTCGACTTTTGTATGCA
AAACAATTGAAAGACCTCGGCGATGAGTTACTAAAAGGCGTTTCAACACG
TGTAAGAGACGCTGCAATCCTTGGGCTTTATTCTGGTCCTAGAATACAGT
CAGGAAATCACGGAAGGATTTCTGTCTACGGAGACTCAAATTGTCTTGAT
ATGACTTTTCGAGATAAAGATTGTCTCTGGCTGTTGGATAGTTTACTGCA
GTACTCCAGAACCGGTCATATATCTGAGCCTTTGTCTTCAGTAGTGTCTA
TCGTCAAGTCAGATCTTGGGGCAAATAAATTCCCACCCAAACGATGTCAA
AACAGTCGGCTGTTTAAATTTTCTGCGGTTATTAAATCACAAAATGGCGA
ACAACTGACTTATAAGGAGCTTCCTCTTTGTAGGAGACCTTCAAACACGG
AAATGCGCATAGACAACTTCTCGATCCCCGATGAATCGACTTATCGACCG
CAGCTGTTGATAAAGAAAAAAGAGTACAATGTTCCACTGGGAATCGGATT
CAGAAATTATTCTCCCTATCAATCCGTTAATCTTGACAACAGGCATTCCC
GAGTTCCCAGAATCGTGCTCCAGCATTCAGAAATCATCGGACCTCGGTTG
TACTGGTTGTACGTCATTTGTGTTTGCAGCGTGTGCTGCGTTGTCATTTG
TGTTTTCTGTCGTCGATTGCGTCCCAAATTCAAGGAAATTCGCCCAATTT
TATCAGCAGCTCCGCATCTTATTTTTAGAAAATAAAATATGTTTTTT
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protein sequence of SMED30005850-orf-1

>SMED30005850-orf-1 ID=SMED30005850-orf-1|Name=SMED30005850-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=589bp
MGKLNLIAAYRALLESEPQASAYPSYVDLTEAPYMWPYSSQPLYSTAMPI
IINITIINSMSVSGIFPIPPVYHAISSRNGDKIRVSVTHSQFLWPWTGYL
ALEITVPDEFSRWQGIAEGYIVAVVQSKNSANDKNLTTNLKIPIKAKVIP
TPLRKMRILWDQFHNLRYPPGYIPRDNIRRPEPLDWTGDHIHTNFKDTYD
YLRNKDYFIEILGSHFGCFNSSNYGTLIIVDPEEEFFNHEQMKLFKDVTE
NGLSLIVFAEWYNVKVMNHLRFFDENTRMWWTPDTGGANIPALNGLLAPF
GIEFSDQVLDGDIKIKNKIIQYNSGTRISRFPNSKKYISRLLYAKQLKDL
GDELLKGVSTRVRDAAILGLYSGPRIQSGNHGRISVYGDSNCLDMTFRDK
DCLWLLDSLLQYSRTGHISEPLSSVVSIVKSDLGANKFPPKRCQNSRLFK
FSAVIKSQNGEQLTYKELPLCRRPSNTEMRIDNFSIPDESTYRPQLLIKK
KEYNVPLGIGFRNYSPYQSVNLDNRHSRVPRIVLQHSEIIGPRLYWLYVI
CVCSVCCVVICVFCRRLRPKFKEIRPILSAAPHLIFRK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0001889liver development
GO:0051216cartilage development
GO:0006508proteolysis
GO:0008202steroid metabolic process
GO:0008203cholesterol metabolic process
GO:0031293membrane protein intracellular domain proteolysis
GO:0034976response to endoplasmic reticulum stress
GO:0036500ATF6-mediated unfolded protein response
GO:0042157lipoprotein metabolic process
GO:0042990regulation of transcription factor import into nucleus
GO:0006629lipid metabolic process
GO:0007040lysosome organization
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR000209Peptidase_S8/S53_dom
IPR023828Peptidase_S8_Ser-AS
Vocabulary: molecular function
TermDefinition
GO:0004252serine-type endopeptidase activity
GO:0004175endopeptidase activity
GO:0004222metalloendopeptidase activity
GO:0008233peptidase activity
GO:0008236serine-type peptidase activity
GO:0016787hydrolase activity
Vocabulary: cellular component
TermDefinition
GO:0000139Golgi membrane
GO:0005783endoplasmic reticulum
GO:0005788endoplasmic reticulum lumen
GO:0005789endoplasmic reticulum membrane
GO:0005794Golgi apparatus
GO:0005795Golgi stack
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePANTHERPTHR43806:SF31coord: 2..391
NoneNo IPR availablePANTHERPTHR43806FAMILY NOT NAMEDcoord: 2..391
NoneNo IPR availableTMHMMTMhelixcoord: 544..563