Protein kinase N2

Overview


Name	Protein kinase N2
Smed ID	SMED30005823
Length (bp)	3674

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein kinase N2 (SMED30005823) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase N2 (SMED30005823) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase N2 (SMED30005823) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase N2 (SMED30005823) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30005823

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30005823	h1SMcG0019698	SmedASXL_007007	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30005823	h1SMcG0019698	SmedASXL_007007	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
muscle cell	SMED30005823	h1SMcG0019698	dd_Smed_v4_7015_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30005823	h1SMcG0019698	dd_Smed_v4_7015_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
zeta neoblast	SMED30005823	h1SMcG0019698	dd_Smed_v4_7015_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
neoblast	SMED30005823	h1SMcG0019698	SMED30005823	smed_20140614	PMID:27523733 Lei et al., 2016
neoblast	SMED30005823	h1SMcG0019698	SMED_04690_V2_2	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30005823	h1SMcG0019698	SMED_04690_V2_2	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30005823	h1SMcG0019698	SMED_04690_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30005823	h1SMcG0019698	SMED_04690_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30005823	h1SMcG0019698	SmWIOct06_027551	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN2 (protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406])

HSP 1 Score: 303.523 bits (776), Expect = 1.795e-86
Identity = 151/323 (46.75%), Postives = 214/323 (66.25%), Query Frame = 2

Query: 2441 TVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
             VLG+GHFGKVLLA+   T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  A FY +C+VL  ++LH+  I+YRDLKLDN+L+D  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+ S+++RLL+R+PE+RLG   +    VK+H FF  IDW+ L  +++ PPFIP +    D   F+ EFT++ P+     +  + SE + E+FR+FD    W
Sbjct:  613 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYIADW 935

[Close]

BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN2 (protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406])

HSP 1 Score: 303.138 bits (775), Expect = 6.214e-86
Identity = 151/323 (46.75%), Postives = 214/323 (66.25%), Query Frame = 2

Query: 2441 TVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
             VLG+GHFGKVLLA+   T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  A FY +C+VL  ++LH+  I+YRDLKLDN+L+D  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+ S+++RLL+R+PE+RLG   +    VK+H FF  IDW+ L  +++ PPFIP +    D   F+ EFT++ P+     +  + SE + E+FR+FD    W
Sbjct:  661 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYIADW 983

[Close]

BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN1 (protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405])

HSP 1 Score: 301.597 bits (771), Expect = 8.490e-86
Identity = 145/304 (47.70%), Postives = 203/304 (66.78%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
            L+  + L VLG+GHFGKVLL++   +  + AIK+++K       E +SL  E+ IL  +    +PFL+NL GCFQ+  H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLH+  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVLLYEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG        VK+  FF ++ W  L +R+L PPF+P L   TD   F+ EFT +  T+
Sbjct:  612 LEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTL 915

[Close]

BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN1 (protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405])

HSP 1 Score: 301.597 bits (771), Expect = 1.062e-85
Identity = 145/304 (47.70%), Postives = 203/304 (66.78%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
            L+  + L VLG+GHFGKVLL++   +  + AIK+++K       E +SL  E+ IL  +    +PFL+NL GCFQ+  H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLH+  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVLLYEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG        VK+  FF ++ W  L +R+L PPF+P L   TD   F+ EFT +  T+
Sbjct:  618 LEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTL 921

[Close]

BLAST of Protein kinase N2 vs. Ensembl Human
Match: PKN3 (protein kinase N3 [Source:HGNC Symbol;Acc:HGNC:17999])

HSP 1 Score: 284.648 bits (727), Expect = 2.952e-80
Identity = 139/299 (46.49%), Postives = 196/299 (65.55%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILST-TPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN 3313
            L     L VLG+GHFGKVLL +   T    AIK+++K    +  E +SL+ E+ IL  +    +PFL++L+ CFQ+  H  F  E+V GGD M  +H+  F E  ARFY++C+VL  +FLH++ IIYRDLKLDN+L+D  G+ K+ DFGL K  + +  +T+TFCGTPEFLAPE++ ++ YTR +DWW LGVLLYEM++GE PFPGD + E+F  I++   P    LS +    I++LL++ PEKRLG G +   ++K   FF + +W  L +R + PPF+P L    D +YFE EFT 
Sbjct:  556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFEGEFTG 854

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: pkn-1 (Protein Kinase N (PKN) homolog [Source:UniProtKB/TrEMBL;Acc:G5EGE3])

HSP 1 Score: 304.294 bits (778), Expect = 1.212e-86
Identity = 149/337 (44.21%), Postives = 209/337 (62.02%), Query Frame = 2

Query: 2390 FRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASI--DWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXXXXXXX-XXLFRNFD 3388
            F S       +++  L++VLG+GHFGKV+L++   T +  A+K ++K       E +SL  E+ I  +  +  +PFL+NL GCFQ+  H+FF +EY  GGD M H+H   F E    FY +C+VL  +FLH  +IIYRD+KLDN+L+D  GY K+ DFGL K NM    KT+TFCGTPEFLAPE++ + +YTR IDWW LGVL++EM++GE PF GDD+ EIF  I+S      + LS ES ++++RLL++ PEKRLGYG      +K   FF  I  +W+KL +R++ PPF P++ +  D   F+ EFT +                   LF NFD
Sbjct:  671 FASSDGAPLTVEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSSRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDDVFDEVRGCFYAACVVLGLDFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRRLLRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPEDVSNFDLEFTQEKARFSAASSTRPITEADQRLFNNFD 1007

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: pkn-1 (Protein Kinase N (PKN) homolog [Source:UniProtKB/TrEMBL;Acc:G5EGE3])

HSP 1 Score: 304.294 bits (778), Expect = 6.742e-86
Identity = 147/327 (44.95%), Postives = 207/327 (63.30%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASI--DWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXXXXXXX-XXLFRNFD 3388
            +++  L++VLG+GHFGKV+L++   T +  A+K ++K       E +SL  E+ I  +  +  +PFL+NL GCFQ+  H+FF +EY  GGD M H+H   F E    FY +C+VL  +FLH  +IIYRD+KLDN+L+D  GY K+ DFGL K NM    KT+TFCGTPEFLAPE++ + +YTR IDWW LGVL++EM++GE PF GDD+ EIF  I+S      + LS ES ++++RLL++ PEKRLGYG      +K   FF  I  +W+KL +R++ PPF P++ +  D   F+ EFT +                   LF NFD
Sbjct:  807 VEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSSRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDDVFDEVRGCFYAACVVLGLDFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRRLLRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPEDVSNFDLEFTQEKARFSAASSTRPITEADQRLFNNFD 1133

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: pkc-2 (Protein kinase C-like 2 [Source:UniProtKB/Swiss-Prot;Acc:P90980])

HSP 1 Score: 262.307 bits (669), Expect = 1.404e-74
Identity = 141/303 (46.53%), Postives = 193/303 (63.70%), Query Frame = 2

Query: 2435 LLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHK-SPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI---KSLSPESTSLIKRLLKRDPEKRLGYGCEG-----TRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
             LTVLG+G FGKVLL +   TK + AIK ++K     D + +    E+ +L L  K +  FL+ L  CFQ+   L+F +E+V GGD M  + +   F E  A FY + I +   FLH + IIYRDLKLDNV+++  G+ K+TDFG+ K N+  D  T TFCGTP+++APEII  + Y + +DWWA GVLL+EM+ G+ PF G+D+ E+F+ I  T  N+   KSLS E+ SL K LL ++P KRL  GC G     +R +KEH FF  IDW K+ +RQ+ PPF PKL    DT  F+SEFT++
Sbjct:  350 FLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPS--FLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAI--TEHNVSYPKSLSKEAVSLCKALLIKNPSKRL--GCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKSADDTSNFDSEFTHE 646

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: pkc-2 (Protein kinase C-like 2 [Source:UniProtKB/Swiss-Prot;Acc:P90980])

HSP 1 Score: 262.692 bits (670), Expect = 2.449e-74
Identity = 141/303 (46.53%), Postives = 193/303 (63.70%), Query Frame = 2

Query: 2435 LLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHK-SPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI---KSLSPESTSLIKRLLKRDPEKRLGYGCEG-----TRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
             LTVLG+G FGKVLL +   TK + AIK ++K     D + +    E+ +L L  K +  FL+ L  CFQ+   L+F +E+V GGD M  + +   F E  A FY + I +   FLH + IIYRDLKLDNV+++  G+ K+TDFG+ K N+  D  T TFCGTP+++APEII  + Y + +DWWA GVLL+EM+ G+ PF G+D+ E+F+ I  T  N+   KSLS E+ SL K LL ++P KRL  GC G     +R +KEH FF  IDW K+ +RQ+ PPF PKL    DT  F+SEFT++
Sbjct:  395 FLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKPS--FLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAI--TEHNVSYPKSLSKEAVSLCKALLIKNPSKRL--GCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKSADDTSNFDSEFTHE 691

[Close]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Match: akt-2 (Serine/threonine-protein kinase akt-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9XTG7])

HSP 1 Score: 253.062 bits (645), Expect = 8.289e-73
Identity = 127/307 (41.37%), Postives = 190/307 (61.89%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHK-SPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIK---SLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
            +D  + L VLGQG FGKV+L +   +  + AIK I+K      +E      E  +L       +PFL  L   FQ++ H+ F +E+  GG+   H+ +   F E   RFY S I+LA  +LH ++I+YRD+KL+N+L+D  G+ K+TDFGL K  +K+  KT+TFCGTPE+LAPE+IE+ +Y R +DWW +GV++YEM+ G  PF   ++ ++F +I  TT ++K    LSPE+ +L+  LL+R P KRLG G +  R+V    FF  +DW     +++ PPF P +   TDT +F+ EFT+ PV +
Sbjct:  177 MDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACV---HPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELI--TTCDLKFPNRLSPEAVTLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTSFFDREFTSMPVQL 478

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0088605)

HSP 1 Score: 294.664 bits (753), Expect = 9.323e-87
Identity = 146/330 (44.24%), Postives = 218/330 (66.06%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXX-XXXXXXXLFRNFDTDLQW 3403
            +D   LL+VLG+GHFGKV+L+++       AIK+++K       E +SL +E+ I  +     +PFL+NL  CFQ+E+H+ F +EY AGGD M H+H   F+E  A FY +C+VL  ++LH+  IIYRDLKLDN+L+D  GY K+ DFGL K  M +  +T TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      + LS E+ ++++RLL+++PE+RLG        VK+ +FF SI W+ L  R++ PPF+P ++ + D   F+ EFT++   +    E    +E +  LF++F    +W
Sbjct:  260 MDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQLLFQDFSYTAEW 589

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0339291)

HSP 1 Score: 296.975 bits (759), Expect = 3.291e-83
Identity = 146/330 (44.24%), Postives = 218/330 (66.06%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXX-XXXXXXXLFRNFDTDLQW 3403
            +D   LL+VLG+GHFGKV+L+++       AIK+++K       E +SL +E+ I  +     +PFL+NL  CFQ+E+H+ F +EY AGGD M H+H   F+E  A FY +C+VL  ++LH+  IIYRDLKLDN+L+D  GY K+ DFGL K  M +  +T TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      + LS E+ ++++RLL+++PE+RLG        VK+ +FF SI W+ L  R++ PPF+P ++ + D   F+ EFT++   +    E    +E +  LF++F    +W
Sbjct:  837 MDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQLLFQDFSYTAEW 1166

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0088601)

HSP 1 Score: 297.36 bits (760), Expect = 3.409e-83
Identity = 146/330 (44.24%), Postives = 218/330 (66.06%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXX-XXXXXXXLFRNFDTDLQW 3403
            +D   LL+VLG+GHFGKV+L+++       AIK+++K       E +SL +E+ I  +     +PFL+NL  CFQ+E+H+ F +EY AGGD M H+H   F+E  A FY +C+VL  ++LH+  IIYRDLKLDN+L+D  GY K+ DFGL K  M +  +T TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      + LS E+ ++++RLL+++PE+RLG        VK+ +FF SI W+ L  R++ PPF+P ++ + D   F+ EFT++   +    E    +E +  LF++F    +W
Sbjct:  860 MDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQLLFQDFSYTAEW 1189

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0088603)

HSP 1 Score: 296.975 bits (759), Expect = 4.382e-83
Identity = 146/330 (44.24%), Postives = 218/330 (66.06%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXX-XXXXXXXLFRNFDTDLQW 3403
            +D   LL+VLG+GHFGKV+L+++       AIK+++K       E +SL +E+ I  +     +PFL+NL  CFQ+E+H+ F +EY AGGD M H+H   F+E  A FY +C+VL  ++LH+  IIYRDLKLDN+L+D  GY K+ DFGL K  M +  +T TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      + LS E+ ++++RLL+++PE+RLG        VK+ +FF SI W+ L  R++ PPF+P ++ + D   F+ EFT++   +    E    +E +  LF++F    +W
Sbjct:  875 MDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQLLFQDFSYTAEW 1204

[Close]

BLAST of Protein kinase N2 vs. Ensembl Fly
Match: Pkn (gene:FBgn0020621 transcript:FBtr0301511)

HSP 1 Score: 297.745 bits (761), Expect = 4.810e-83
Identity = 146/330 (44.24%), Postives = 218/330 (66.06%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXX-XXXXXXXLFRNFDTDLQW 3403
            +D   LL+VLG+GHFGKV+L+++       AIK+++K       E +SL +E+ I  +     +PFL+NL  CFQ+E+H+ F +EY AGGD M H+H   F+E  A FY +C+VL  ++LH+  IIYRDLKLDN+L+D  GY K+ DFGL K  M +  +T TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      + LS E+ ++++RLL+++PE+RLG        VK+ +FF SI W+ L  R++ PPF+P ++ + D   F+ EFT++   +    E    +E +  LF++F    +W
Sbjct:  954 MDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQLLFQDFSYTAEW 1283

[Close]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Match: pkn3 (protein kinase N3 [Source:ZFIN;Acc:ZDB-GENE-030131-1902])

HSP 1 Score: 330.487 bits (846), Expect = 2.878e-96
Identity = 153/319 (47.96%), Postives = 211/319 (66.14%), Query Frame = 2

Query: 2438 LTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPVTIXXXXXXXXXXXXXXLFRNFD 3388
            ++VLG+GHFGKVLLA+   T  + AIK+++K    T  E DSL  E+ I   I    +PFL+NL GCFQ+  H+ F +EY  GGD M H+H + F E  ARFY +C++L  EFLH   I+YRDLKLDN+LMD  G+ ++ DFGL K  M +  +T+TFCGTPEFLAPE++ + NYTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + +SPES S+I++LL+++ EKRLG G +   +VK+H FF  IDW  L ++++ PPF+P +    D   F+ EFT  +PV          S    E F +FD
Sbjct:  598 ISVLGRGHFGKVLLAEFKRTGKLYAIKALKKGDVVTRDEVDSLMCEKRIFETINASRHPFLVNLYGCFQTPDHVCFVMEYSPGGDLMTHIHNNIFSERQARFYSACVLLGLEFLHQNRIVYRDLKLDNLLMDSDGFVRIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDSNYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFMSPESVSVIQKLLQKNSEKRLGAGEQDANEVKKHRFFQGIDWEALLAKRVKPPFLPSIKTAADVSNFDEEFTRLKPVLTPPQTPFFLSAEQQEFFADFD 916

[Close]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Match: pkn3 (protein kinase N3 [Source:ZFIN;Acc:ZDB-GENE-030131-1902])

HSP 1 Score: 330.487 bits (846), Expect = 4.160e-96
Identity = 153/319 (47.96%), Postives = 211/319 (66.14%), Query Frame = 2

Query: 2438 LTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPVTIXXXXXXXXXXXXXXLFRNFD 3388
            ++VLG+GHFGKVLLA+   T  + AIK+++K    T  E DSL  E+ I   I    +PFL+NL GCFQ+  H+ F +EY  GGD M H+H + F E  ARFY +C++L  EFLH   I+YRDLKLDN+LMD  G+ ++ DFGL K  M +  +T+TFCGTPEFLAPE++ + NYTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + +SPES S+I++LL+++ EKRLG G +   +VK+H FF  IDW  L ++++ PPF+P +    D   F+ EFT  +PV          S    E F +FD
Sbjct:  617 ISVLGRGHFGKVLLAEFKRTGKLYAIKALKKGDVVTRDEVDSLMCEKRIFETINASRHPFLVNLYGCFQTPDHVCFVMEYSPGGDLMTHIHNNIFSERQARFYSACVLLGLEFLHQNRIVYRDLKLDNLLMDSDGFVRIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDSNYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFMSPESVSVIQKLLQKNSEKRLGAGEQDANEVKKHRFFQGIDWEALLAKRVKPPFLPSIKTAADVSNFDEEFTRLKPVLTPPQTPFFLSAEQQEFFADFD 935

[Close]

Query: 2438 LTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPVTIXXXXXXXXXXXXXXLFRNFD 3388
            ++VLG+GHFGKVLLA+   T  + AIK+++K    T  E DSL  E+ I   I    +PFL+NL GCFQ+  H+ F +EY  GGD M H+H + F E  ARFY +C++L  EFLH   I+YRDLKLDN+LMD  G+ ++ DFGL K  M +  +T+TFCGTPEFLAPE++ + NYTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + +SPES S+I++LL+++ EKRLG G +   +VK+H FF  IDW  L ++++ PPF+P +    D   F+ EFT  +PV          S    E F +FD
Sbjct:  617 ISVLGRGHFGKVLLAEFKRTGKLYAIKALKKGDVVTRDEVDSLMCEKRIFETINASRHPFLVNLYGCFQTPDHVCFVMEYSPGGDLMTHIHNNIFSERQARFYSACVLLGLEFLHQNRIVYRDLKLDNLLMDSDGFVRIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDSNYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFMSPESVSVIQKLLQKNSEKRLGAGEQDANEVKKHRFFQGIDWEALLAKRVKPPFLPSIKTAADVSNFDEEFTRLKPVLTPPQTPFFLSAEQQEFFADFD 935

[Close]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Match: BX321890.2 (protein kinase N3 [Source:NCBI gene;Acc:323182])

HSP 1 Score: 330.102 bits (845), Expect = 4.592e-96
Identity = 153/319 (47.96%), Postives = 211/319 (66.14%), Query Frame = 2

Query: 2438 LTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPVTIXXXXXXXXXXXXXXLFRNFD 3388
            ++VLG+GHFGKVLLA+   T  + AIK+++K    T  E DSL  E+ I   I    +PFL+NL GCFQ+  H+ F +EY  GGD M H+H + F E  ARFY +C++L  EFLH   I+YRDLKLDN+LMD  G+ ++ DFGL K  M +  +T+TFCGTPEFLAPE++ + NYTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + +SPES S+I++LL+++ EKRLG G +   +VK+H FF  IDW  L ++++ PPF+P +    D   F+ EFT  +PV          S    E F +FD
Sbjct:  617 ISVLGRGHFGKVLLAEFKRTGKLYAIKALKKGDVVTRDEVDSLMCEKRIFETINASRHPFLVNLYGCFQTPDHVCFVMEYSPGGDLMTHIHNNIFSERQARFYSACVLLGLEFLHQNRIVYRDLKLDNLLMDSDGFVRIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDSNYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFMSPESVSVIQKLLQKNSEKRLGAGEQDANEVKKHRFFQGIDWEALLAKRVKPPFLPSIKTAADVSNFDEEFTRLKPVLTPPQTPFFLSAEQQEFFADFD 935

[Close]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Match: PKN2 (zgc:153916 [Source:NCBI gene;Acc:567134])

HSP 1 Score: 303.908 bits (777), Expect = 1.309e-86
Identity = 150/330 (45.45%), Postives = 214/330 (64.85%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
            L   + + VLG+GHFGKVLLA    T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  + FY +C+VL  +FLHD  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      K LS E+ S+++RLL+R+PE+RLG G     +VK H FF  +DW  L ++++ PPF+P +    D   F+ EFT++ P+     +  + +  + +LF +FD    W
Sbjct:  634 LSDFKCVAVLGRGHFGKVLLADYKTTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHADVFSETRSVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFKDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPKYLSTEAISIMRRLLRRNPERRLGAGERDAEEVKRHPFFRDMDWPGLLAKKIRPPFVPTITSREDVSNFDDEFTSEAPILTPPREPRILTLGEQDLFADFDYIADW 963

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: jph3 (junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974])

HSP 1 Score: 314.694 bits (805), Expect = 4.770e-91
Identity = 141/304 (46.38%), Postives = 205/304 (67.43%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
            +D    ++VLG+GHFGKVLL +  ET    AIK+++K    +  E +SL  E+ I   +    +PFL+NL GCFQ++ H  F +EY+ GGD M H+H + F E  ARFY +C+VL  +FLH++ IIYRDLKLDN+LMD  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YT  +DWW LGVL++EM++GE PFPGDD+ E+F  I++      + LS ++ ++I++LL++ PE+RLG G     ++K   FF  IDW+ LY++Q+ PP +P L D  D + F+ EFT Q   +
Sbjct:  520 VDDFTFISVLGRGHFGKVLLGQFKETGKNFAIKALKKRDIVSRDELESLQCEKRIFEAVNSSGHPFLVNLFGCFQTQGHACFVMEYMPGGDLMMHIHSNVFSEPTARFYSACVVLGLQFLHEKKIIYRDLKLDNLLMDASGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTYAVDWWGLGVLIFEMLVGECPFPGDDEEEVFDSIVNEEVRYPRFLSNDAINIIRKLLRKSPERRLGAGVGDAEEIKPQLFFQEIDWDALYAQQVKPPVVPILSDPFDIRNFDEEFTGQKAIL 823

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: jph3 (junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974])

HSP 1 Score: 314.309 bits (804), Expect = 7.205e-91
Identity = 141/304 (46.38%), Postives = 205/304 (67.43%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
            +D    ++VLG+GHFGKVLL +  ET    AIK+++K    +  E +SL  E+ I   +    +PFL+NL GCFQ++ H  F +EY+ GGD M H+H + F E  ARFY +C+VL  +FLH++ IIYRDLKLDN+LMD  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YT  +DWW LGVL++EM++GE PFPGDD+ E+F  I++      + LS ++ ++I++LL++ PE+RLG G     ++K   FF  IDW+ LY++Q+ PP +P L D  D + F+ EFT Q   +
Sbjct:  532 VDDFTFISVLGRGHFGKVLLGQFKETGKNFAIKALKKRDIVSRDELESLQCEKRIFEAVNSSGHPFLVNLFGCFQTQGHACFVMEYMPGGDLMMHIHSNVFSEPTARFYSACVVLGLQFLHEKKIIYRDLKLDNLLMDASGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTYAVDWWGLGVLIFEMLVGECPFPGDDEEEVFDSIVNEEVRYPRFLSNDAINIIRKLLRKSPERRLGAGVGDAEEIKPQLFFQEIDWDALYAQQVKPPVVPILSDPFDIRNFDEEFTGQKAIL 835

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: jph3 (junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974])

HSP 1 Score: 313.923 bits (803), Expect = 9.792e-91
Identity = 141/304 (46.38%), Postives = 205/304 (67.43%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
            +D    ++VLG+GHFGKVLL +  ET    AIK+++K    +  E +SL  E+ I   +    +PFL+NL GCFQ++ H  F +EY+ GGD M H+H + F E  ARFY +C+VL  +FLH++ IIYRDLKLDN+LMD  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YT  +DWW LGVL++EM++GE PFPGDD+ E+F  I++      + LS ++ ++I++LL++ PE+RLG G     ++K   FF  IDW+ LY++Q+ PP +P L D  D + F+ EFT Q   +
Sbjct:  526 VDDFTFISVLGRGHFGKVLLGQFKETGKNFAIKALKKRDIVSRDELESLQCEKRIFEAVNSSGHPFLVNLFGCFQTQGHACFVMEYMPGGDLMMHIHSNVFSEPTARFYSACVVLGLQFLHEKKIIYRDLKLDNLLMDASGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTYAVDWWGLGVLIFEMLVGECPFPGDDEEEVFDSIVNEEVRYPRFLSNDAINIIRKLLRKSPERRLGAGVGDAEEIKPQLFFQEIDWDALYAQQVKPPVVPILSDPFDIRNFDEEFTGQKAIL 829

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: jph3 (junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974])

HSP 1 Score: 314.309 bits (804), Expect = 1.355e-90
Identity = 141/304 (46.38%), Postives = 205/304 (67.43%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
            +D    ++VLG+GHFGKVLL +  ET    AIK+++K    +  E +SL  E+ I   +    +PFL+NL GCFQ++ H  F +EY+ GGD M H+H + F E  ARFY +C+VL  +FLH++ IIYRDLKLDN+LMD  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YT  +DWW LGVL++EM++GE PFPGDD+ E+F  I++      + LS ++ ++I++LL++ PE+RLG G     ++K   FF  IDW+ LY++Q+ PP +P L D  D + F+ EFT Q   +
Sbjct:  560 VDDFTFISVLGRGHFGKVLLGQFKETGKNFAIKALKKRDIVSRDELESLQCEKRIFEAVNSSGHPFLVNLFGCFQTQGHACFVMEYMPGGDLMMHIHSNVFSEPTARFYSACVVLGLQFLHEKKIIYRDLKLDNLLMDASGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTYAVDWWGLGVLIFEMLVGECPFPGDDEEEVFDSIVNEEVRYPRFLSNDAINIIRKLLRKSPERRLGAGVGDAEEIKPQLFFQEIDWDALYAQQVKPPVVPILSDPFDIRNFDEEFTGQKAIL 863

[Close]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Match: jph3 (junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974])

HSP 1 Score: 313.538 bits (802), Expect = 1.457e-90
Identity = 141/300 (47.00%), Postives = 204/300 (68.00%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
            +D    ++VLG+GHFGKVLL +  ET    AIK+++K    +  E +SL  E+ I   +    +PFL+NL GCFQ++ H  F +EY+ GGD M H+H + F E  ARFY +C+VL  +FLH++ IIYRDLKLDN+LMD  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YT  +DWW LGVL++EM++GE PFPGDD+ E+F  I++      + LS ++ ++I++LL++ PE+RLG G     ++K   FF  IDW+ LY++Q+ PP +P L D  D + F+ EFT Q
Sbjct:  542 VDDFTFISVLGRGHFGKVLLGQFKETGKNFAIKALKKRDIVSRDELESLQCEKRIFEAVNSSGHPFLVNLFGCFQTQGHACFVMEYMPGGDLMMHIHSNVFSEPTARFYSACVVLGLQFLHEKKIIYRDLKLDNLLMDASGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTYAVDWWGLGVLIFEMLVGECPFPGDDEEEVFDSIVNEEVRYPRFLSNDAINIIRKLLRKSPERRLGAGVGDAEEIKPQLFFQEIDWDALYAQQVKPPVVPILSDPFDIRNFDEEFTGQ 841

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn1 (protein kinase N1 [Source:MGI Symbol;Acc:MGI:108022])

HSP 1 Score: 304.294 bits (778), Expect = 8.952e-87
Identity = 150/325 (46.15%), Postives = 212/325 (65.23%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXX-XXXXXXXXXXLFRNFD 3388
            L+  + L VLG+GHFGKVLL++   +  + AIK+++K       E +SL  E+ IL  + +  +PFL+NL GCFQ+  H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLH+  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVLLYEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG        VK+  FF S+ W+ L +R+L PPF+P L   TD   F+ EFT +  T+         +  +   FR+FD
Sbjct:  616 LEDFKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFRDFD 940

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn1 (protein kinase N1 [Source:MGI Symbol;Acc:MGI:108022])

HSP 1 Score: 304.294 bits (778), Expect = 9.811e-87
Identity = 150/325 (46.15%), Postives = 212/325 (65.23%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXX-XXXXXXXXXXLFRNFD 3388
            L+  + L VLG+GHFGKVLL++   +  + AIK+++K       E +SL  E+ IL  + +  +PFL+NL GCFQ+  H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLH+  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVLLYEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG        VK+  FF S+ W+ L +R+L PPF+P L   TD   F+ EFT +  T+         +  +   FR+FD
Sbjct:  621 LEDFKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFRDFD 945

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn2 (protein kinase N2 [Source:MGI Symbol;Acc:MGI:109211])

HSP 1 Score: 301.212 bits (770), Expect = 8.940e-86
Identity = 148/323 (45.82%), Postives = 212/323 (65.63%), Query Frame = 2

Query: 2441 TVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
             VLG+GHFGKVLLA+   T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  A FY +C+VL  ++LH+  I+YRDLKLDN+L+D  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+ S+++RLL+R+PE+RLG G +    VK+H FF   DW+ L  +++ PPF+P +    D   F+ EFT++ P+     +  +  E + E+F +FD    W
Sbjct:  612 AVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPREPRILLEEEQEMFHDFDYVADW 934

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn2 (protein kinase N2 [Source:MGI Symbol;Acc:MGI:109211])

HSP 1 Score: 300.442 bits (768), Expect = 3.278e-85
Identity = 148/323 (45.82%), Postives = 212/323 (65.63%), Query Frame = 2

Query: 2441 TVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
             VLG+GHFGKVLLA+   T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  A FY +C+VL  ++LH+  I+YRDLKLDN+L+D  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+ S+++RLL+R+PE+RLG G +    VK+H FF   DW+ L  +++ PPF+P +    D   F+ EFT++ P+     +  +  E + E+F +FD    W
Sbjct:  660 AVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPREPRILLEEEQEMFHDFDYVADW 982

[Close]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Match: Pkn2 (protein kinase N2 [Source:MGI Symbol;Acc:MGI:109211])

HSP 1 Score: 300.056 bits (767), Expect = 3.329e-85
Identity = 148/323 (45.82%), Postives = 212/323 (65.63%), Query Frame = 2

Query: 2441 TVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
             VLG+GHFGKVLLA+   T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  A FY +C+VL  ++LH+  I+YRDLKLDN+L+D  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+ S+++RLL+R+PE+RLG G +    VK+H FF   DW+ L  +++ PPF+P +    D   F+ EFT++ P+     +  +  E + E+F +FD    W
Sbjct:  644 AVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPREPRILLEEEQEMFHDFDYVADW 966

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|Q63433|PKN1_RAT (Serine/threonine-protein kinase N1 OS=Rattus norvegicus OX=10116 GN=Pkn1 PE=1 SV=2)

HSP 1 Score: 306.605 bits (784), Expect = 9.611e-87
Identity = 150/325 (46.15%), Postives = 213/325 (65.54%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXX-XXXXXXXXXXLFRNFD 3388
            L+  + L VLG+GHFGKVLL++   +  + AIK+++K       E +SL  E+ IL  + +  +PFL+NL GCFQ+  H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLH+  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVLLYEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG        VK+  FF ++DW+ L +R+L PPF+P L   TD   F+ EFT +  T+         +  +   FR+FD
Sbjct:  616 LEDFKFLAVLGRGHFGKVLLSEFHSSGELFAIKALKKGDIVARDEVESLMCEKRILATVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRTLDWDALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFRDFD 940

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|P70268|PKN1_MOUSE (Serine/threonine-protein kinase N1 OS=Mus musculus OX=10090 GN=Pkn1 PE=1 SV=3)

HSP 1 Score: 304.294 bits (778), Expect = 6.262e-86
Identity = 150/325 (46.15%), Postives = 212/325 (65.23%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXX-XXXXXXXXXXLFRNFD 3388
            L+  + L VLG+GHFGKVLL++   +  + AIK+++K       E +SL  E+ IL  + +  +PFL+NL GCFQ+  H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLH+  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVLLYEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG        VK+  FF S+ W+ L +R+L PPF+P L   TD   F+ EFT +  T+         +  +   FR+FD
Sbjct:  616 LEDFKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFRDFD 940

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|A7MBL8|PKN2_DANRE (Serine/threonine-protein kinase N2 OS=Danio rerio OX=7955 GN=pkn2 PE=2 SV=1)

HSP 1 Score: 304.294 bits (778), Expect = 8.317e-86
Identity = 150/330 (45.45%), Postives = 214/330 (64.85%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
            L   + + VLG+GHFGKVLLA    T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  + FY +C+VL  +FLHD  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      K LS E+ S+++RLL+R+PE+RLG G     +VK H FF  +DW  L ++++ PPF+P +    D   F+ EFT++ P+     +  + +  + +LF +FD    W
Sbjct:  647 LSDFKCVAVLGRGHFGKVLLADYKTTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHADVFSETRSVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFKDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPKYLSTEAISIMRRLLRRNPERRLGAGERDAEEVKRHPFFRDMDWPGLLAKKIRPPFVPTITSREDVSNFDDEFTSEAPILTPPREPRILTLGEQDLFADFDYIADW 976

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|A1A4I4|PKN1_BOVIN (Serine/threonine-protein kinase N1 OS=Bos taurus OX=9913 GN=PKN1 PE=2 SV=1)

HSP 1 Score: 303.138 bits (775), Expect = 1.538e-85
Identity = 149/325 (45.85%), Postives = 211/325 (64.92%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXX-XXXXXXXXXXLFRNFD 3388
            L+  + L VLG+GHFGKVLL++   +  + AIK+++K       E +SL  E+ IL  +    +PFL+NL GCFQ+  H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLH+  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVLLYEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG        VK+  FF ++ W+ L +R+L PPF+P L   TD   F+ EFT +  T+         +  +   FR+FD
Sbjct:  614 LEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTNAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWDALLARRLPPPFVPTLAGRTDVSNFDEEFTGEAPTLSPPRDARPLTATEQAAFRDFD 938

[Close]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Match: sp|Q16513|PKN2_HUMAN (Serine/threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1)

HSP 1 Score: 303.138 bits (775), Expect = 2.984e-85
Identity = 151/323 (46.75%), Postives = 214/323 (66.25%), Query Frame = 2

Query: 2441 TVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
             VLG+GHFGKVLLA+   T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  A FY +C+VL  ++LH+  I+YRDLKLDN+L+D  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+ S+++RLL+R+PE+RLG   +    VK+H FF  IDW+ L  +++ PPFIP +    D   F+ EFT++ P+     +  + SE + E+FR+FD    W
Sbjct:  661 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYIADW 983

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A5C6NIS9 (Non-specific serine/threonine protein kinase OS=Takifugu flavidus OX=433684 GN=D4764_20G0008470 PE=3 SV=1)

HSP 1 Score: 323.939 bits (829), Expect = 5.638e-97
Identity = 158/340 (46.47%), Postives = 219/340 (64.41%), Query Frame = 2

Query: 2411 HQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSK---------PNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPVTIXXXXXXXXXXXXXXLFRNFDTDL 3397
            H  +D  + ++VLG+GHFGKVLLA+   +  + AIK+++K    +  E DSL  E+ I  +I    +PFL+NL GCFQ+E H+ F + Y  GGD M H+H S F E+ ARFY SC++L  EFLH   IIYRDLKLDN+LMD  G+ ++ DFGL K           M    +T+TFCGTPEFLAPE++ E NYTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LSP+S SLI++LL+++PE RLG G E   +VK H FF + DW+ L ++++ PPF+P +    D   F+ EFT  +PV        V +    ++F +FD  L
Sbjct:   20 HLQMDDFKCISVLGRGHFGKVLLAEFKRSGKLYAIKALKKGDIVSRDEVDSLVCEKRIFEVINASRHPFLVNLHGCFQTEEHVCFVMAYSPGGDLMTHIHTSIFTEKQARFYSSCVLLGLEFLHQNKIIYRDLKLDNLLMDADGFVRIADFGLCKEGMSHVMSCAGMGHGDRTSTFCGTPEFLAPEVLTESNYTRSVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDDVRCPRFLSPQSASLIQQLLQKNPETRLGAGEEDALQVKSHRFFQATDWDALLAKRVKPPFLPVIRSPKDVSNFDEEFTRLRPVLTLPRTACVLTPQQQQIFADFDFSL 359

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A3Q2ZNH1 (Non-specific serine/threonine protein kinase OS=Kryptolebias marmoratus OX=37003 PE=3 SV=1)

HSP 1 Score: 327.791 bits (839), Expect = 9.298e-97
Identity = 152/309 (49.19%), Postives = 212/309 (68.61%), Query Frame = 2

Query: 2402 SVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKS-LSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPV 3322
            S+    +D   L++VLG+GHFGKVLLA+  +T  + AIK+++K    T  E DSL +E+ I  +I    +PFL+NL GCFQ+  H+ F +EY+ GGD M H+H   F E   RFY +C++L  EFLH   IIYRDLKLDN+LMD  G+ K+TDFGL K  M    +T+TFCGTPEFLAPE++ + NYTR +DWW LGVL+YEM++GESPFPG+D+ E+F  I++      + L P++ S++++LLKR+P KRLG G     +VK   F+ +IDW  L S++L PPF+P + ++TD   F+S+FT  QP 
Sbjct:  136 SLSRMQVDDFRLISVLGRGHFGKVLLAEFKKTGRLYAIKALKKRDIVTRDEVDSLMSEKRIFEMINASRHPFLVNLHGCFQTSDHVCFVMEYLPGGDLMIHIHSDVFSEAQTRFYSACVLLGLEFLHLNKIIYRDLKLDNLLMDADGFVKITDFGLCKEGMGHGDRTSTFCGTPEFLAPEVLTDDNYTRAVDWWGLGVLIYEMLVGESPFPGEDEEEVFDSIVNDDVQYPTNLPPDAVSIMQKLLKRNPLKRLGAGERDANEVKGEKFYETIDWEALMSKKLKPPFLPSIKELTDVSNFDSDFTRLQPA 444

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A3Q1CAR4 (Non-specific serine/threonine protein kinase OS=Amphiprion ocellaris OX=80972 PE=3 SV=1)

HSP 1 Score: 320.472 bits (820), Expect = 1.049e-95
Identity = 152/325 (46.77%), Postives = 216/325 (66.46%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPVTIXXXXXXXXXXXXXXLFRNFD 3388
            ++  + ++VLG+GHFGKVLLA+  ++  + AIK+++K    T  E DSL  E++I  +I    +PFL+NL GCFQ+  H+ F + Y  GGD M H+H S F E+  +FY SC++L  EFLH   I+YRDLKLDN+LMD  G+ ++ DFGL K  M    +T+TFCGTPEFLAPE++ + NYTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LSPES SLI++LL+++PE RLG G E   ++K   FF  IDW+ L +++L PPF+P +    D   F+ EFT  +PV        + +    E+F +FD
Sbjct:   24 MEDFKCISVLGRGHFGKVLLAEYKKSGKLYAIKALKKGDIVTRDEVDSLMCEKKIFEVINGTRHPFLVNLYGCFQTADHVCFVMAYSPGGDLMTHIHTSIFTEKQTQFYSSCVLLGLEFLHQNKIVYRDLKLDNLLMDADGFVRIADFGLCKEGMGHGDRTSTFCGTPEFLAPEVLIDNNYTRSVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDDVRYPRFLSPESVSLIQKLLQKNPEMRLGAGEEDASEIKRQKFFQEIDWDALLAKKLKPPFLPVIRAPQDVSNFDKEFTRLKPVLTLPRTPCILTAEQQEIFADFD 348

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A1A8IK28 (Protein kinase N3 (Fragment) OS=Nothobranchius kuhntae OX=321403 GN=PKN3 PE=4 SV=1)

HSP 1 Score: 329.717 bits (844), Expect = 2.041e-95
Identity = 152/304 (50.00%), Postives = 212/304 (69.74%), Query Frame = 2

Query: 2417 VLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIK-SLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPV 3322
            ++D   L++VLG+GHFGKVLLA+  +T  + AIK+++K    T  E DSL +E+ I  +I    +PFL+NL GCFQ+  H+ F +EY+AGGD M H+H   F E   RFY +C++L  EFLH   IIYRDLKLDN+LMD  G+ K+TDFGL K  +    +T+TFCGTPEFLAPE++ + +YTR +DWW LGVL+YEM++GESPFPG+D+ E+F  I++       SL P++ S++++LLK++P KRLG G    ++VK   FF  IDW  L +++L PPF+P + D TD   F+S+FT  QPV
Sbjct:  312 LMDDFRLISVLGRGHFGKVLLAEFKKTGRLYAIKALKKRDIVTRGEVDSLMSEKRIFEMINASRHPFLVNLHGCFQTSDHVCFVMEYLAGGDLMIHIHNDVFSEAQTRFYSACVLLGLEFLHLNKIIYRDLKLDNLLMDADGFVKITDFGLCKEGVGHGDQTSTFCGTPEFLAPEVLTDDSYTRAVDWWGLGVLVYEMLVGESPFPGEDEEEVFDSIVNNDVQYPTSLHPDAVSIMQKLLKKNPLKRLGAGERDAKEVKGEKFFQPIDWEALMTKKLKPPFLPSIKDSTDVSNFDSDFTQLQPV 615

[Close]

BLAST of Protein kinase N2 vs. TrEMBL
Match: A0A1A8KCJ3 (Protein kinase N3 (Fragment) OS=Nothobranchius kuhntae OX=321403 GN=PKN3 PE=4 SV=1)

HSP 1 Score: 317.39 bits (812), Expect = 3.979e-95
Identity = 148/293 (50.51%), Postives = 204/293 (69.62%), Query Frame = 2

Query: 2450 GQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIK-SLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPV 3322
            G+GHFGKVLLA+  +T  + AIK+++K    T  E DSL +E+ I  +I    +PFL+NL GCFQ+  H+ F +EY+AGGD M H+H   F E   RFY +C++L  EFLH   IIYRDLKLDN+LMD  G+ K+TDFGL K  +    +T+TFCGTPEFLAPE++ + +YTR +DWW LGVL+YEM++GESPFPG+D+ E+F  I++       SL P++ S++++LLK++P KRLG G    ++VK   FF  IDW  L +++L PPF+P + D TD   F+S+FT  QPV
Sbjct:    1 GRGHFGKVLLAEFKKTGRLYAIKALKKRDIVTRGEVDSLMSEKRIFEMINASRHPFLVNLHGCFQTSDHVCFVMEYLAGGDLMIHIHNDVFSEAQTRFYSACVLLGLEFLHLNKIIYRDLKLDNLLMDADGFVKITDFGLCKEGVGHGDQTSTFCGTPEFLAPEVLTDDSYTRAVDWWGLGVLVYEMLVGESPFPGEDEEEVFDSIVNNDVQYPTSLHPDAVSIMQKLLKKNPLKRLGAGERDAKEVKGEKFFQPIDWEALMTKKLKPPFLPSIKDSTDVSNFDSDFTQLQPV 293

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: pkn3 (protein kinase N3 [Source:ZFIN;Acc:ZDB-GENE-030131-1902])

HSP 1 Score: 329.717 bits (844), Expect = 1.125e-96
Identity = 153/328 (46.65%), Postives = 214/328 (65.24%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPVTIXXXXXXXXXXXXXXLFRNFDTDL 3397
            ++  + ++VLG+GHFGKVLLA+   T  + AIK+++K    T  E DSL  E+ I   I   ++PFL+NL GCFQ+  H+ F +EY  GGD M H+H S F E   RFY +C++L  EFLH   I+YRDLKLDN+LMD  G+ ++ DFGL K  M +  +T+TFCGTPEFLAPE++ +  YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LSPES S+I++LL+++PEKRLG G +   +VK+H FF  IDW  L ++++ PPF+P +    D   F+ EFT  +PV                +F +FD  L
Sbjct:  534 MEDFKCISVLGRGHFGKVLLAEHKSTGKMYAIKALKKGDVVTRDEVDSLMCEKRIFETINASHHPFLVNLHGCFQTCDHVCFVMEYSPGGDLMTHIHNSIFTERQTRFYAACVLLGLEFLHQNQIVYRDLKLDNLLMDADGFVRIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDSTYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSPESVSIIQKLLQKNPEKRLGAGEQDANEVKKHRFFQGIDWEALLAKRVKPPFLPTIKTSGDVSNFDEEFTRLKPVLTPPQTPFFLGAEQQGIFADFDFSL 861

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: pkn2 (serine/threonine-protein kinase N2 [Source:NCBI gene;Acc:103040528])

HSP 1 Score: 305.834 bits (782), Expect = 6.600e-88
Identity = 157/347 (45.24%), Postives = 226/347 (65.13%), Query Frame = 2

Query: 2387 TFRSRSVCHQ------VLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
            TFR+ ++C        VL   + + VLG+GHFGKVLLA+   T  + AIK+++K    +  E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLH+  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      + LS E+ S+++RLL+R+PE+RLG G     +VK+H FF ++DW  L  +++ PPF+P +   +D   F+ EFT++ PV     D+   S  + E+F +FD    W
Sbjct:  534 TFRA-ALCENLYFFTPVLRDFKCVAVLGRGHFGKVLLAEYSSTGEMFAIKALKKGDIVSRDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRATFYAACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFRDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISVMRRLLRRNPERRLGGGERDAEEVKKHLFFRNMDWTGLLGKKVKPPFVPVIQSPSDVSNFDEEFTSEAPVLTPPRDQRPLSREEQEMFTDFDYIADW 879

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: zgc:153916 (serine/threonine-protein kinase N2 [Source:NCBI gene;Acc:103027669])

HSP 1 Score: 304.294 bits (778), Expect = 1.701e-87
Identity = 150/337 (44.51%), Postives = 220/337 (65.28%), Query Frame = 2

Query: 2399 RSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
            + +C  + D  + + VLG+GHFGKVLLA+   T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLH+  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      + LS E+ S+++RLL+R+P++RLG G     +VK+H F  ++DW  L ++++ PPF+P +    D   F+ EFT++ P+     +  V +  + ELF +FD    W
Sbjct:  537 QQLCFSIRD-FKCVAVLGRGHFGKVLLAEYRSTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHADVFSEPRAVFYAACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYQDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPDRRLGAGERDAEEVKKHPFLRNVDWGALLAKKIQPPFVPTIKGREDVSNFDDEFTSEAPILTPPREPRVLTANEQELFTDFDYIADW 872

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: pkn1a (protein kinase N1a [Source:ZFIN;Acc:ZDB-GENE-061207-17])

HSP 1 Score: 304.294 bits (778), Expect = 2.025e-87
Identity = 145/300 (48.33%), Postives = 204/300 (68.00%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
            L    L+ VLG+GHFGKVLLA+  ++ S+ AIK+++K       E +SL  E+ I   +    +PFL+NL  CFQ+  H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLHD  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+ ++++RLL+R+PE+RLG G +   +VK+ SFF ++DW  L  R+L PPF+P +    D   F+ EFT +
Sbjct:  552 LQDFRLIAVLGRGHFGKVLLAEYKKSGSMYAIKALKKGDIVARDEVESLMCEKRIFETVNTSQHPFLVNLFACFQTPEHVCFVMEYTAGGDLMMHIHADVFTEPRAVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTDGYVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSSEAIAIMRRLLRRNPERRLGSGEKDAEEVKKQSFFRNMDWEALLLRKLPPPFVPSIGGKEDVSNFDEEFTAE 851

[Close]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Match: pkn1b (protein kinase N1b [Source:ZFIN;Acc:ZDB-GENE-070424-87])

HSP 1 Score: 299.671 bits (766), Expect = 4.384e-87
Identity = 151/325 (46.46%), Postives = 213/325 (65.54%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFD 3388
            L    L+ VLG+GHFGKVLL++   + ++ AIK+++K       E +SL  E+ I   +   ++PFL+NL  CFQ++ H+ F +EY AGGD M H+H   F E  + FY +C+VL  +FLHD  I+YRDLKLDN+L+D  G+ K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+ SL++RLL+R+PE+RLG        VK+  FF +IDW  L  R++VPPF+P L    D   F++EFT + P      +    S  D E FR+FD
Sbjct:  396 LQDFRLVAVLGRGHFGKVLLSEYKRSGTLYAIKALKKGDIIARDEVESLMCEKRIFETVNSSHHPFLVNLFACFQTDEHVCFVMEYTAGGDLMMHIHADVFSEPRSVFYAACVVLGLQFLHDNKIVYRDLKLDNLLLDTDGFVKIADFGLCKEGMGFGDRTSTFCGTPEFLAPEVLTDSSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISLMRRLLRRNPERRLGSTERDAEDVKKQPFFRNIDWEALLQRKVVPPFVPSLGGREDVSNFDAEFTTEAPALTPPRERRTLSRKDQEWFRDFD 720

[Close]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 243.817 bits (621), Expect = 1.116e-70
Identity = 123/317 (38.80%), Postives = 190/317 (59.94%), Query Frame = 2

Query: 2387 TFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEED-ARFYISCIVLAFEFLH-DQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
            T  S+      ++  + L +LG+G FGKV+L +   T    A+K ++K       E      E  +L   +   +PFL  L   FQ+   L F +EYV GG+   H+ +     ED  RFY + IV A ++LH +++++YRDLKL+N+++D  G+ K+ DFGL K  +       TFCGTPE+LAPE++E+ +Y R +DWW LGV++YEM+ G  PF   D  ++F +IL       ++LS ++ +L+  LLK+DP++RLG G +  +++  HSFFA I W  +Y R++ PPF P++   TDT+YF+ EFT Q +TI
Sbjct:  136 TILSKPKSKVTMNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVL---QTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFDEEFTAQTITI 449

[Close]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399])

HSP 1 Score: 243.047 bits (619), Expect = 6.922e-70
Identity = 120/287 (41.81%), Postives = 179/287 (62.37%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVH---KSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKL 3268
            LD   LL VLG+G FGKV+LA++ E     AIK+++K       + +    E+ +L++  +H  PFL +L G FQ++ HLFF +E++ GGD M H+    K        RFY + ++   +FLH  +IIYRDLKLDNVL+D  G+ K+ DFG+ K ++      TTFCGTP+++APEI+  + Y   +DWW++GVL+YEM++G+SPF G D+ E+F  I   TP+  + LS  S +++  L +RD  KRLG        ++ H FF +IDW  L +R++ PPF PK+
Sbjct:  249 LDHFHLLKVLGKGSFGKVMLAELKEQGKFFAIKALKKEVVLMGDDVECTMVEKRVLLMACEH--PFLTHLCGTFQTKEHLFFVMEFLTGGDLMFHIQDKGKFDLPTGTNRFYAAEVICGLQFLHSHNIIYRDLKLDNVLLDREGHVKIADFGMCKEHVGAGNLATTFCGTPDYIAPEILLGRAYGTSVDWWSMGVLIYEMLIGQSPFYGSDEDELFEAIKGHTPHYPRWLSDSSRNILSCLFERDHTKRLG----AVGDIRLHPFFKNIDWPSLEARKITPPFKPKV 529

[Close]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399])

HSP 1 Score: 222.246 bits (565), Expect = 7.818e-66
Identity = 113/270 (41.85%), Postives = 172/270 (63.70%), Query Frame = 2

Query: 2468 KVLLAKV-IETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVH-KSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKL 3268
            +V LA++    ++  AIK+++K       + +    E+ IL L   H  P+L +L   FQ++ HL F +EY+ GGD M H+  K  F  + A FY + IV   +FLHDQ IIYRDLKLDN+L+D  G+ K+ DFG+ K N+  D +  TFCGTP+++APEI+  + Y   +DWW+ GVLLYEM++G+SPF GDD+ E+F  I ++ P   + ++ +S  ++  LL+R+P KRLG     T ++++H FF +I+W  L  R+L PPF P++
Sbjct:    1 QVFLAELKSRPRNFFAIKALKKDVVIMSDDVECTLVEKRILSLAWGH--PYLAHLYSTFQTKEHLMFVMEYLNGGDLMFHIQVKGRFEIDRATFYAAEIVSGLQFLHDQGIIYRDLKLDNILLDKDGHVKIADFGMCKENIVGDVRAGTFCGTPDYIAPEIVIGQKYNCSVDWWSFGVLLYEMLIGQSPFRGDDEEELFESIRTSVPYYPRWITKDSRDILPLLLEREPMKRLGV----TGEIRQHPFFRTINWEALEKRELEPPFKPRV 264

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BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 222.246 bits (565), Expect = 8.778e-64
Identity = 114/302 (37.75%), Postives = 180/302 (59.60%), Query Frame = 2

Query: 2429 LELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHK-SPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPEST-SLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
             + LTVLG+G FGKVLLAK        A+K ++K+      E   + AER +L+   +H  PFL+ L   FQS   L+F ++YV GG+   H+ +   F E  A+FY + I  A  +LH  +I+YRDLK +N+L+D  G+  LTDFGL K  +   + T TFCGTPE+LAPE++++  Y R +DWW LG +LYEM+ G  PF   + ++++  IL     ++  +  +  S+++ LL +DP +RLG       ++K H FF++I+WN L ++++  P+ P +    D   F+  FT +P+++
Sbjct:   92 FDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRH--PFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLG-ATSDILEIKNHVFFSTINWNDLDAKRIPSPYNPGVSGPCDLHNFDPAFTAEPLSM 390

[Close]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 197.593 bits (501), Expect = 6.742e-57
Identity = 105/266 (39.47%), Postives = 153/266 (57.52%), Query Frame = 2

Query: 2507 CAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHK-SPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKS-LSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFE 3298
             ++K+ ++ +     + +    E+ IL  I   + PFL+ L   F+   +L+  LEYV GG+   H+ +   F E  +RFY + IVLAFE+LH  D+IYRDLK +N+L+D  GY ++TDFG +K   +   +T T CGTPE+LAPEII  K Y + +DWWALGVL+YEM  G  PF  D   +I+  I+S      S  S +   L++ LL+ D  KR G    G   +K H +F++ DW  +Y R++  PFIPK     D   F+
Sbjct:    7 VSLKATKRTKVVKLKQVEHTLNEKRILQAI---SFPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFD 266

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: PKC1 (Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC) [Source:SGD;Acc:S000000201])

HSP 1 Score: 290.812 bits (743), Expect = 4.602e-82
Identity = 133/304 (43.75%), Postives = 202/304 (66.45%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIK-SLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTI 3328
            LD   LL VLG+G+FGKV+L+K   T  +CAIK ++K     + + +S  AE+++ +L  K  +PFL NL   FQ+E  ++FA+E++ GGD M HV         A+FY + ++LA ++ HD  +IYRDLKL+N+L+   G+ K+ D+GL K  M +  +T+TFCGTPEF+APEI++E+ YT+ +DWWA GVLLY+M+L +SPF GDD+ E+F+ IL+  P     ++ E   + + LL +DPEKRLG G     +V E  FF +I+++ + + ++ PP+IP++    DT YFE EFT+ P T+
Sbjct:  821 LDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTL 1124

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609])

HSP 1 Score: 234.572 bits (597), Expect = 1.033e-65
Identity = 119/302 (39.40%), Postives = 182/302 (60.26%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHK-SPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI--KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
            +D  +LL V+G+G FGKV+  +  +T+ V A+K+I+K+   + +E     AER +L  +   + PF++ L   FQS   L+F L ++ GG+   H+ K   F    ARFY + ++ A + LH  D++YRDLK +N+L+D  G+  L DFGL K NMK D KT TFCGTPE+LAPE++    YT+ +DWW LGVLLYEM+ G  P+  +D  +++  IL   P +       ++  L+  LL RDP +RLGY   G  +++ H FF+ + W +L  +  +PP+ P + +  DT  F+ EFT +
Sbjct:  344 IDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARV---DCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ-EPLVFPDGFDRDAKDLLIGLLSRDPTRRLGY--NGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTRE 639

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: SCH9 (AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248])

HSP 1 Score: 235.728 bits (600), Expect = 3.435e-65
Identity = 124/312 (39.74%), Postives = 188/312 (60.26%), Query Frame = 2

Query: 2387 TFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSP-FIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPE-IIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKS--LSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFT 3310
            T++     H      E+L +LG+G FG+V   K  +T+ + A+K + K       E      ER IL+     ++PF++ L   FQ+   L+   +Y++GG+   H+ K   F E+ A+FYI+ +VLA E LHD DI+YRDLK +N+L+D +G   L DFGLSK ++K   +T TFCGT E+LAPE +++E  YT+++D+W+LGVL++EM  G SPF  +++++++  I           LS E  S +K LL R+P+ RLG   +G R+++ H FFA IDW  L  +++ PPF P L   TDT  F+ EFT
Sbjct:  398 TYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLK--DRTNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDG-RELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFT 706

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710])

HSP 1 Score: 231.491 bits (589), Expect = 1.053e-64
Identity = 119/303 (39.27%), Postives = 180/303 (59.41%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHV-HKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTT---PNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
            +D  +LL V+G+G FGKV+  +  +T+ + A+K+++KA   +  E     AER +L  +   + PF++ L   FQS   L+  L ++ GG+   H+ H+  F    +RFYI+ ++ A + LH  D+IYRDLK +N+L+D  G+  L DFGL K NMK + KT TFCGTPE+LAPEI+  + YT+ +DWW LG+LLYEM+ G  P+  ++   ++  IL      P+     P +  L+  LL RDP +RL  G  GT +++ H FF  I W KL  +  +PP+ P +    DT  F+ EFT +
Sbjct:  341 IDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARV---DCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPD--GFDPAAKDLLIGLLSRDPSRRL--GVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKE 636

[Close]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Match: KIN82 (Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000000687])

HSP 1 Score: 206.453 bits (524), Expect = 5.327e-56
Identity = 126/324 (38.89%), Postives = 176/324 (54.32%), Query Frame = 2

Query: 2375 SFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMG--HVHKSPFI-EEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLS-------KPNMK----WDTK-------TTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTT---PNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDD 3274
            SF   F+  +V  Q  +K+ LL   GQG  GKV L +  +T  + A+K + K       +   +  E+EIL      ++PF++ L   FQ++ +L+  +EY  GG+F       KS  I EEDA+FY S +V A E+LH    IYRDLK +N+L+   G+  L+DF LS       KP MK     DTK       T +F GT E+LAPE+I    +T  +DWW LG+L+YEM+ G +PF GD+  E FS IL+     P+ K +S     LIK+LL ++  KRLG    G   +K H FF  + W+ L  R   PP IP L+D
Sbjct:  309 SFGNKFQDITVEPQSFEKIRLL---GQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILAT---SDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLG-SKSGAADIKRHPFFKKVQWSFL--RNQDPPLIPALND 623

[Close]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO43312 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYZ0])

HSP 1 Score: 297.745 bits (761), Expect = 3.646e-85
Identity = 143/337 (42.43%), Postives = 217/337 (64.39%), Query Frame = 2

Query: 2402 SVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPE-IIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
            +  H  +     ++VLG+GHFGKV+LA+   T  + AIK+++K       E +SL AE+ I +   K  +PFL+NL  CFQ++ H+ F +EY  GGD M H+H   F E    FY +C+VL  ++LHD +I+YRDLKLDN+L+D  GY K+ DFGL K +M +  +T TFCGTPEFLAPE ++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      + LS E+ ++++RLL+R+PE+RLG   +   +VK+  FF  + W+ L +R++ PPF+P++    D   F+ EFT+ +P+     +    +  +  LF +F+    W
Sbjct:  603 NTSHMSMSNFRCISVLGRGHFGKVILAEYRNTNELFAIKALKKGDIIAREEVESLLAEKRIFLTANKTRHPFLVNLFACFQTQEHVCFVMEYAPGGDLMMHIHADVFAESRTVFYTACVVLGLQYLHDHEIVYRDLKLDNLLLDSEGYVKIADFGLCKEDMGYGARTGTFCGTPEFLAPEMLVTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIAIMRRLLRRNPERRLGAAEKDAEEVKKQPFFRDMRWDDLLARKIRPPFVPQVKHAEDVSNFDEEFTSEEPILTPPKEARSLNPDEQGLFADFNYTADW 939

[Close]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO35585 (Protein kinase C [Source:UniProtKB/TrEMBL;Acc:A7SL27])

HSP 1 Score: 253.447 bits (646), Expect = 1.604e-71
Identity = 137/312 (43.91%), Postives = 192/312 (61.54%), Query Frame = 2

Query: 2393 RSRSVCHQV-LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKS-PFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKS-LSPESTSLIKRLLKRDPEKRLGYGCEGTR-KVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
            R R V  ++ L     + VLG+G FGKVLLA+   T  V AIK ++K     D + +    ER +L L   H  PFL +L   FQ+   LFF +EYV GGD M  + KS  F E  +RFY + +VLA +FLH   +IYRDLKLDNVL+D  G+ KL DFG+ K NM     TTTFCGTP+++APEI++E+ Y   +DWWALGVL+YEM+ G+ PF  +++ ++F  IL         LS E+ S++K  + ++  KRLG     T   ++EH+FF  I++ KL +RQ+ PPF PK+   TD   F+++FT +
Sbjct:  370 RRRHVLRKMTLKDFTFIKVLGKGSFGKVLLAERKGTDEVYAIKILKKESVLQDDDVECTMIERRVLALSAGH--PFLTSLHSSFQTVERLFFVMEYVNGGDLMFQIQKSRKFDENRSRFYAAEVVLALQFLHQNGVIYRDLKLDNVLLDADGHIKLADFGMCKENMAPGKTTTTFCGTPDYIAPEILQEQPYGFSVDWWALGVLMYEMMAGQPPFEAENEEDLFESILHDDVLYPVWLSREAVSILKGFMTKNYLKRLGCTPTSTESSIREHAFFRLINFEKLEARQINPPFKPKIRSRTDVGNFDTDFTKE 679

[Close]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO44938 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU22])

HSP 1 Score: 243.817 bits (621), Expect = 1.522e-69
Identity = 125/313 (39.94%), Postives = 196/313 (62.62%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEED-ARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPF--------PGDDDRE-IFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLG-YGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPV 3322
            ++   L+ V+G+G + KV+L ++ +TK + A+K ++K     D + D +  E+ +    +  N+PFL+ L  CFQ+   LFF +EYV+GGD M H+ +   + ED ARFY + I  A  FLH++ +IYRDLKLDNVL+D  G+ KLTD+G+ K  ++    T+TFCGTP ++APEI+  ++Y   +DWWALGVLLYEM+ G SPF        P  +  + +F +IL     I +SLS ++ S++K  L ++P +RLG +   G   +  H+FF ++ W +L +RQ+ PPF P+ +D    + F+ +FTN+ V
Sbjct:  219 VNDFNLIRVIGRGSYAKVMLVELKKTKRIYAMKVVKKELVNDDEDIDWVQTEKHVFE--QASNHPFLVGLHSCFQTSSRLFFVIEYVSGGDLMYHMQRQRRLPEDHARFYSAEICCALNFLHEKGVIYRDLKLDNVLLDSDGHIKLTDYGMCKEGIRPGDVTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDIVGSADNPDQNTEDYLFQVILEKPIRIPRSLSVKAASILKGYLNKNPTERLGCHPQTGFADITSHAFFRTVSWEQLEARQVTPPFKPRQEDPYGLENFDPQFTNEDV 529

[Close]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO31895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWM6])

HSP 1 Score: 239.965 bits (611), Expect = 6.048e-68
Identity = 121/302 (40.07%), Postives = 190/302 (62.91%), Query Frame = 2

Query: 2426 KLELLTVLGQGHFGKVLLAKVI---ETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKS-PFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKS-LSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
            + ELL VLGQG FGKV L + +   +  ++ A+K ++KA         ++  ER+IL+ ++   +PF++ L   FQ+E  ++  L+++ GGD    + K   F EED +FY++ + LA + LH   IIYRDLK +N+L+D  G+  LTDFGLSK + + D KT +FCGT E++APE++  + +++  DWW+ GVL++EM+ G  PF G D ++  +MIL     +   L+PE+ SL+++L KR+P  RLG G  G   +K+H FF++I+W  LY R++ PPF P      D  YF+ EFT++
Sbjct:    8 QFELLKVLGQGSFGKVFLVRKVIGADAGTLYAMKVLKKATLKVRDRMRTM-KERDILVDVQ---HPFIVRLNYAFQTEGKVYLILDFLRGGDLFTRLSKEIMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDASGHVALTDFGLSKES-EHDQKTYSFCGTVEYMAPEVVNRRGHSQAADWWSYGVLMFEMLTGSLPFQGKDRKDTMNMILKAKLGMPQFLTPEAQSLLRQLFKRNPLNRLGAGDLGIEDIKKHPFFSTINWELLYKREIKPPFKPAAGRADDAFYFDPEFTSK 304

HSP 2 Score: 89.3521 bits (220), Expect = 3.914e-18
Identity = 59/220 (26.82%), Postives = 109/220 (49.55%), Query Frame = 2

Query: 2387 TFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFI-EEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVL-MDIHGYA---KLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPF 3031
             F  R+ C  +LD+ E+   +G+G +              C  K+  K  A    E        E+ IL+R  ++P +++L   +++ + ++  +E + GG+ +  + K   + E +A   +  +     FLH++ +++RDLK  N++  D  G     ++ DFG +K     +    T C T  F+APE+++++ Y    D W+LGVLLY M+ G +PF
Sbjct:  344 AFPIRTTC--ILDEYEIKEEIGKGAYSSC---------RRCVNKADGKEYAVKIFEKPKKDPSEEMEILLRFGHHPNIVHLRDAYEAGKQVYIVMELMRGGELLDRILKHKCLSEREAGNIMYTLTSTIAFLHEEGVVHRDLKPSNIMYADDSGTPESLRIVDFGFAKQMRATNGLLMTPCYTANFVAPEVLKKQGYDAACDIWSLGVLLYTMLSGLTPF 552

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BLAST of Protein kinase N2 vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2])

HSP 1 Score: 230.335 bits (586), Expect = 1.754e-66
Identity = 117/298 (39.26%), Postives = 177/298 (59.40%), Query Frame = 2

Query: 2435 LLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEED-ARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKS-LSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPV 3322
             L V+G+G FGKV L+K  +     AIK + K+      E   + AER +L+    H  PFL+ L   FQ++  L+F L+YV GG+   H+ +  +  E  ARFY + I  A  +LH   IIYRDLK +N+L+D  G+  LTDFGL K  +     T+TFCGTPE+LAPE++ +++Y + +DWW LG +LYEM+ G  PF   D  E++  IL     +++ +S  +  +++ LL++D  KRLG G      ++ HSFF SI+W +L +R + PP+ P +    D ++F+ EF  +PV
Sbjct:   76 FLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTH--PFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPYNPNVSGQLDLKHFDPEFVREPV 371

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BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: pkn3 (serine/threonine-protein kinase N2 [Source:NCBI gene;Acc:101157143])

HSP 1 Score: 315.849 bits (808), Expect = 3.766e-91
Identity = 152/325 (46.77%), Postives = 208/325 (64.00%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTN-QPVTIXXXXXXXXXXXXXXLFRNFD 3388
            ++  + L+VLG+GHFGKVLLA+  ++  + AIK+++K    T  E DSL  E+ I   I K  +PFL+NL GCFQ+  H+ F + Y +GGD M H+H   F      FY SC++L  EFLH   I+YRDLKLDN+LMD  G+ K+ DFGL K  M    +T+TFCGTPEFLAPE++ + +YTR +DWW LGVL+YEM+LGE PFPGDD+ EIF  I++       SLS E+ SLI++LL++DP  RLG G E   ++K H FF  ++W+ L +++L PPF P +    D   F+ EFT  +PV          +    ELF +FD
Sbjct:  599 MEDFQCLSVLGRGHFGKVLLAEYKKSGKLYAIKALKKGEIVTRDEIDSLMCEKRIFEAINKAQHPFLVNLHGCFQTADHVCFVMAYSSGGDLMKHIHNHIFNRNQTLFYSSCVLLGLEFLHQNKIVYRDLKLDNLLMDAEGFVKIADFGLCKEGMGHGDRTSTFCGTPEFLAPEVLIDNSYTRCVDWWELGVLIYEMLLGECPFPGDDEEEIFDSIVNEEVRCPASLSKEAQSLIQQLLQKDPTLRLGAGEEDASEIKRHPFFQGMNWDALLAKKLKPPFQPVIRAPQDVSNFDEEFTQLKPVLTLPRTPCPLTSEQQELFADFD 923

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BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: pkn2 (protein kinase N2 [Source:NCBI gene;Acc:101158798])

HSP 1 Score: 310.457 bits (794), Expect = 8.078e-89
Identity = 151/330 (45.76%), Postives = 215/330 (65.15%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ-PVTIXXXXXXXXXXXXXXLFRNFDTDLQW 3403
            L     + VLG+GHFGKVLLA+   T  + AIK+++K       E DSL  E+ I   +    +PFL+NL  CFQ+  H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLHD  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ E +YTR +DWW LGVL++EM++GESPFPGDD+ E+F  I++      + LS E+ S+++RLL+R PE+RLG G +   +VK+H FF ++DW  L ++++ PPF+P + D  D   F+ EFT++ P+     +  + +  +  LF +FD    W
Sbjct:  645 LQDFRCVAVLGRGHFGKVLLAEYKSTGEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTPEHVCFVMEYAAGGDLMMHIHADVFSEPRAVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYRDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRSPERRLGAGEKDAEEVKKHPFFRNMDWGGLLAKKVKPPFVPTIQDANDVSNFDEEFTSEAPILTPPREPRMLNSEEQGLFSDFDYIADW 974

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BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: pkn1a (protein kinase N1 [Source:NCBI gene;Acc:101164700])

HSP 1 Score: 303.523 bits (776), Expect = 3.481e-88
Identity = 144/297 (48.48%), Postives = 203/297 (68.35%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEF 3307
            L    L+ VLG+GHFGKVLL++  +T ++ AIK+++K       E DSL  E+ I  ++   ++PFLINL  CFQ+ +H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLHD  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG G +   +VK+  FF S+DW  L  R++ PPF+P +    D   F+ EF
Sbjct:  429 LQDFRLIAVLGRGHFGKVLLSEYKKTGTMYAIKALKKGDIIARDEVDSLMCEKRIFEIVNMSHHPFLINLFACFQTSQHVCFVMEYTAGGDLMMHIHTDVFTEPRAVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTDGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRRLLRRNPERRLGSGEKDAEEVKKQPFFRSVDWEALLQRKVPPPFVPSIRGKEDVSNFDEEF 725

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BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: pkn1a (protein kinase N1 [Source:NCBI gene;Acc:101164700])

HSP 1 Score: 305.064 bits (780), Expect = 1.012e-87
Identity = 144/297 (48.48%), Postives = 203/297 (68.35%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEF 3307
            L    L+ VLG+GHFGKVLL++  +T ++ AIK+++K       E DSL  E+ I  ++   ++PFLINL  CFQ+ +H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLHD  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG G +   +VK+  FF S+DW  L  R++ PPF+P +    D   F+ EF
Sbjct:  547 LQDFRLIAVLGRGHFGKVLLSEYKKTGTMYAIKALKKGDIIARDEVDSLMCEKRIFEIVNMSHHPFLINLFACFQTSQHVCFVMEYTAGGDLMMHIHTDVFTEPRAVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTDGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRRLLRRNPERRLGSGEKDAEEVKKQPFFRSVDWEALLQRKVPPPFVPSIRGKEDVSNFDEEF 843

[Close]

BLAST of Protein kinase N2 vs. Ensembl Medaka
Match: pkn1a (protein kinase N1 [Source:NCBI gene;Acc:101164700])

HSP 1 Score: 305.064 bits (780), Expect = 2.495e-87
Identity = 144/297 (48.48%), Postives = 203/297 (68.35%), Query Frame = 2

Query: 2420 LDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEF 3307
            L    L+ VLG+GHFGKVLL++  +T ++ AIK+++K       E DSL  E+ I  ++   ++PFLINL  CFQ+ +H+ F +EY AGGD M H+H   F E  A FY +C+VL  +FLHD  I+YRDLKLDN+L+D  GY K+ DFGL K  M +  +T+TFCGTPEFLAPE++ + +YTR +DWW LGVL+YEM++GESPFPGDD+ E+F  I++      + LS E+  +++RLL+R+PE+RLG G +   +VK+  FF S+DW  L  R++ PPF+P +    D   F+ EF
Sbjct:  602 LQDFRLIAVLGRGHFGKVLLSEYKKTGTMYAIKALKKGDIIARDEVDSLMCEKRIFEIVNMSHHPFLINLFACFQTSQHVCFVMEYTAGGDLMMHIHTDVFTEPRAVFYAACVVLGLQFLHDHKIVYRDLKLDNLLLDTDGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIGIMRRLLRRNPERRLGSGEKDAEEVKKQPFFRSVDWEALLQRKVPPPFVPSIRGKEDVSNFDEEF 898

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BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000014536.1 (SMESG000014536.1)

HSP 1 Score: 1981.84 bits (5133), Expect = 0.000e+0
Identity = 1027/1073 (95.71%), Postives = 1028/1073 (95.81%), Query Frame = 2

Query:  281 MYFLFNRIHIESAYISSLNKSFVYGLKIKSNKKDNEKLNNLRLYSVEKKKLFAVSLKLLLQENLCMNTAGMTLERITDLLLENLDNGIMNIYDYIYQECSICNKNHETCQLESGPFCFCRLKSLNINESQHYSGIIKFKFCSFMGMYSTSYLKEILINNAPRLVDNQFKSEYNTK---------------TKRRCEVVIKEQIVCSDWTTGPLMISGEFEVYNAKEIEVQVWEDPKEIGETKHXXXXXXXXXXXXIENKHHSNSINISMEPDGFMTGLVKYTPIKRSISENPELNKENRPLLRKIGVKRRMNIMAKLTGHRLARHVEAHIPVSLWLDWFQNHVDRLAIPVDSNRNEPEQKENKISGLCRMVRRFVIKSFGLNNKKLLITPCKSPLVNKIANESYRQISKSPMPNRVPKTPKFNQTNPRAICKFNHPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKKNKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVTRSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSILQSPFPLDSQYDFIPNSCRSVSRSMIS----------------ASTHSKHCNNISQASTKTNQTADKCVHHDWXXXXXXXXXXLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDGHGDIETEVANXXXXXXXXXXXXXXXXXNNSFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXXXXXXXXXLFRNFDTDLQWQ 3406
            MYFLFNRIHIESAYISSLNKSFVYGLKIKSNKKDNEKLNNLRLYSVEKKKLFAVSLKLLLQENLCMNTAGMTLERITDLLLENLDNGIMNIYDYIYQECSICNKNHETCQLESGPFCFCRLKSLNINESQHYSGIIKFKFCSFMGMYSTSYLKEILINNAPRLVDNQFKSEYN+K               TKRRCEVVIKEQIVCSDWTTGPLMISGEFEVYNAKEIEVQVWEDPKEIGETKHLVAVAVVSLQALIENKHHSNSINISMEPDGFMTGLVKYTPIKRSISENPELNKENRPLLRKIGVKRRMNIMAKLTGHRLARHVEAHIPVSLWLDWFQNHVDRLAIPVDSNRNEPEQKENK              SFGLNNKKLLITPCKSPLVNKIANESYRQISKSPMPNRVPKTPKFNQTNPRAICKFNHPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKKNKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVTRSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSILQSPFPLDSQYDFIPNSCRSVSRSMIS                ASTHSKHCNNISQASTKTNQTADKCVHHDWDSCCYDDSSYLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDGHGDIETEVANGDGEGEREEDEEDIDIDNNSFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIEHDDEEVDSEFDDELFRNFDTDLQWQ
Sbjct:    1 MYFLFNRIHIESAYISSLNKSFVYGLKIKSNKKDNEKLNNLRLYSVEKKKLFAVSLKLLLQENLCMNTAGMTLERITDLLLENLDNGIMNIYDYIYQECSICNKNHETCQLESGPFCFCRLKSLNINESQHYSGIIKFKFCSFMGMYSTSYLKEILINNAPRLVDNQFKSEYNSKDCLNVFHRNLNYPAKTKRRCEVVIKEQIVCSDWTTGPLMISGEFEVYNAKEIEVQVWEDPKEIGETKHLVAVAVVSLQALIENKHHSNSINISMEPDGFMTGLVKYTPIKRSISENPELNKENRPLLRKIGVKRRMNIMAKLTGHRLARHVEAHIPVSLWLDWFQNHVDRLAIPVDSNRNEPEQKENK--------------SFGLNNKKLLITPCKSPLVNKIANESYRQISKSPMPNRVPKTPKFNQTNPRAICKFNHPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKKNKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVTRSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSILQSPFPLDSQYDFIPNSCRSVSRSMISVTTVSLCAIELIFTVQASTHSKHCNNISQASTKTNQTADKCVHHDWDSCCYDDSSYLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDGHGDIETEVANGDGEGEREEDEEDIDIDNNSFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIEHDDEEVDSEFDDELFRNFDTDLQWQ 1059

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BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000014533.1 (SMESG000014533.1)

HSP 1 Score: 1853.57 bits (4800), Expect = 0.000e+0
Identity = 962/1008 (95.44%), Postives = 963/1008 (95.54%), Query Frame = 2

Query:  476 MNTAGMTLERITDLLLENLDNGIMNIYDYIYQECSICNKNHETCQLESGPFCFCRLKSLNINESQHYSGIIKFKFCSFMGMYSTSYLKEILINNAPRLVDNQFKSEYNTK---------------TKRRCEVVIKEQIVCSDWTTGPLMISGEFEVYNAKEIEVQVWEDPKEIGETKHXXXXXXXXXXXXIENKHHSNSINISMEPDGFMTGLVKYTPIKRSISENPELNKENRPLLRKIGVKRRMNIMAKLTGHRLARHVEAHIPVSLWLDWFQNHVDRLAIPVDSNRNEPEQKENKISGLCRMVRRFVIKSFGLNNKKLLITPCKSPLVNKIANESYRQISKSPMPNRVPKTPKFNQTNPRAICKFNHPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKKNKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVTRSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSILQSPFPLDSQYDFIPNSCRSVSRSMIS----------------ASTHSKHCNNISQASTKTNQTADKCVHHDWXXXXXXXXXXLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDGHGDIETEVANXXXXXXXXXXXXXXXXXNNSFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXXXXXXXXXLFRNFDTDLQWQ 3406
            MNTAGMTLERITDLLLENLDNGIMNIYDYIYQECSICNKNHETCQLESGPFCFCRLKSLNINESQHYSGIIKFKFCSFMGMYSTSYLKEILINNAPRLVDNQFKSEYN+K               TKRRCEVVIKEQIVCSDWTTGPLMISGEFEVYNAKEIEVQVWEDPKEIGETKHLVAVAVVSLQALIENKHHSNSINISMEPDGFMTGLVKYTPIKRSISENPELNKENRPLLRKIGVKRRMNIMAKLTGHRLARHVEAHIPVSLWLDWFQNHVDRLAIPVDSNRNEPEQKENK              SFGLNNKKLLITPCKSPLVNKIANESYRQISKSPMPNRVPKTPKFNQTNPRAICKFNHPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKKNKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVTRSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSILQSPFPLDSQYDFIPNSCRSVSRSMIS                ASTHSKHCNNISQASTKTNQTADKCVHHDWDSCCYDDSSYLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDGHGDIETEVANGDGEGEREEDEEDIDIDNNSFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIEHDDEEVDSEFDDELFRNFDTDLQWQ
Sbjct:    1 MNTAGMTLERITDLLLENLDNGIMNIYDYIYQECSICNKNHETCQLESGPFCFCRLKSLNINESQHYSGIIKFKFCSFMGMYSTSYLKEILINNAPRLVDNQFKSEYNSKDCLNVFHRNLNYPAKTKRRCEVVIKEQIVCSDWTTGPLMISGEFEVYNAKEIEVQVWEDPKEIGETKHLVAVAVVSLQALIENKHHSNSINISMEPDGFMTGLVKYTPIKRSISENPELNKENRPLLRKIGVKRRMNIMAKLTGHRLARHVEAHIPVSLWLDWFQNHVDRLAIPVDSNRNEPEQKENK--------------SFGLNNKKLLITPCKSPLVNKIANESYRQISKSPMPNRVPKTPKFNQTNPRAICKFNHPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKKNKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVTRSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSILQSPFPLDSQYDFIPNSCRSVSRSMISVTTVSLCAIELIFTVQASTHSKHCNNISQASTKTNQTADKCVHHDWDSCCYDDSSYLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDGHGDIETEVANGDGEGEREEDEEDIDIDNNSFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIEHDDEEVDSEFDDELFRNFDTDLQWQ 994

[Close]

BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000014536.1 (SMESG000014536.1)

HSP 1 Score: 1237.25 bits (3200), Expect = 0.000e+0
Identity = 646/662 (97.58%), Postives = 646/662 (97.58%), Query Frame = 2

Query: 1469 MPNRVPKTPKFNQTNPRAICKFNHPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKKNKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVTRSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSILQSPFPLDSQYDFIPNSCRSVSRSMIS----------------ASTHSKHCNNISQASTKTNQTADKCVHHDWXXXXXXXXXXLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDGHGDIETEVANXXXXXXXXXXXXXXXXXNNSFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIXXXXXXXXXXXXXXLFRNFDTDLQWQ 3406
            MPNRVPKTPKFNQTNPRAICKFNHPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKKNKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVTRSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSILQSPFPLDSQYDFIPNSCRSVSRSMIS                ASTHSKHCNNISQASTKTNQTADKCVHHDWDSCCYDDSSYLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDGHGDIETEVANGDGEGEREEDEEDIDIDNNSFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIEHDDEEVDSEFDDELFRNFDTDLQWQ
Sbjct:    1 MPNRVPKTPKFNQTNPRAICKFNHPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKKNKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVTRSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSILQSPFPLDSQYDFIPNSCRSVSRSMISVTTVSLCAIELIFTVQASTHSKHCNNISQASTKTNQTADKCVHHDWDSCCYDDSSYLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDGHGDIETEVANGDGEGEREEDEEDIDIDNNSFNGTFRSRSVCHQVLDKLELLTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIEHDDEEVDSEFDDELFRNFDTDLQWQ 662

[Close]

BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000065035.1 (SMESG000065035.1)

HSP 1 Score: 285.034 bits (728), Expect = 1.249e-80
Identity = 140/294 (47.62%), Postives = 198/294 (67.35%), Query Frame = 2

Query: 2438 LTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
            ++VLG+GHFGKVLLA+        AIK+++KA      E ++L +E+ I   I +  +PFL+NL+ CFQS  H+ F +EY  GGD M H+    F E  A FY  CIVL  +FLH + I+YRDLKLDN+L+D  GY K+ DFGL K NM    +T+TFCGTPEFLAPE++ E++YTR +DWW LGVL+YEM++GE PFPGD++ EIF  I++      + LS E+T +++RL++R PE RLG        VK+  FF S++++ L ++++ P F+PKL +  D   F+SEFT +
Sbjct:  574 ISVLGRGHFGKVLLAQYKSNGKYYAIKALKKAEILARNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQE 867

[Close]

BLAST of Protein kinase N2 vs. Planmine SMEST
Match: SMESG000065035.1 (SMESG000065035.1)

HSP 1 Score: 284.648 bits (727), Expect = 1.255e-80
Identity = 140/294 (47.62%), Postives = 198/294 (67.35%), Query Frame = 2

Query: 2438 LTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREILILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDARFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMKWDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPGDDDREIFSMILSTTPNI-KSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKVKEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQ 3316
            ++VLG+GHFGKVLLA+        AIK+++KA      E ++L +E+ I   I +  +PFL+NL+ CFQS  H+ F +EY  GGD M H+    F E  A FY  CIVL  +FLH + I+YRDLKLDN+L+D  GY K+ DFGL K NM    +T+TFCGTPEFLAPE++ E++YTR +DWW LGVL+YEM++GE PFPGD++ EIF  I++      + LS E+T +++RL++R PE RLG        VK+  FF S++++ L ++++ P F+PKL +  D   F+SEFT +
Sbjct:  559 ISVLGRGHFGKVLLAQYKSNGKYYAIKALKKAEILARNELETLTSEKRIFQTITESKHPFLVNLLSCFQSTEHVLFVMEYARGGDLMMHIQTDIFEEPRAVFYAGCIVLGIDFLHSKKIVYRDLKLDNLLLDEQGYVKMADFGLCKENMGHGDRTSTFCGTPEFLAPEVLVERDYTRSVDWWGLGVLIYEMLVGECPFPGDNEEEIFDSIVNHEIRYPRHLSMEATLIMRRLMRRTPENRLGASARDAEDVKKQPFFRSLNFDDLLAKRVKPTFVPKLANEEDVSNFDSEFTQE 852

The following BLAST results are available for this feature:

BLAST of Protein kinase N2 vs. Ensembl Human
BLAST of Protein kinase N2 vs. Ensembl Celegans
BLAST of Protein kinase N2 vs. Ensembl Fly
BLAST of Protein kinase N2 vs. Ensembl Zebrafish
BLAST of Protein kinase N2 vs. Ensembl Xenopus
BLAST of Protein kinase N2 vs. Ensembl Mouse
BLAST of Protein kinase N2 vs. UniProt/SwissProt
BLAST of Protein kinase N2 vs. TrEMBL
BLAST of Protein kinase N2 vs. Ensembl Cavefish
BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
BLAST of Protein kinase N2 vs. Ensembl Yeast
BLAST of Protein kinase N2 vs. Ensembl Nematostella
BLAST of Protein kinase N2 vs. Ensembl Medaka
BLAST of Protein kinase N2 vs. Planmine SMEST

BLAST of Protein kinase N2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PKN2	1.795e-86	46.75	protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:940...	[more]
PKN2	6.214e-86	46.75	protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:940...	[more]
PKN1	8.490e-86	47.70	protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:940...	[more]
PKN1	1.062e-85	47.70	protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:940...	[more]
PKN3	2.952e-80	46.49	protein kinase N3 [Source:HGNC Symbol;Acc:HGNC:179...	[more]

BLAST of Protein kinase N2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pkn-1	1.212e-86	44.21	Protein Kinase N (PKN) homolog [Source:UniProtKB/...	[more]
pkn-1	6.742e-86	44.95	Protein Kinase N (PKN) homolog [Source:UniProtKB/...	[more]
pkc-2	1.404e-74	46.53	Protein kinase C-like 2 [Source:UniProtKB/Swiss-P...	[more]
pkc-2	2.449e-74	46.53	Protein kinase C-like 2 [Source:UniProtKB/Swiss-P...	[more]
akt-2	8.289e-73	41.37	Serine/threonine-protein kinase akt-2 [Source:Uni...	[more]

BLAST of Protein kinase N2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pkn	9.323e-87	44.24	gene:FBgn0020621 transcript:FBtr0088605	[more]
Pkn	3.291e-83	44.24	gene:FBgn0020621 transcript:FBtr0339291	[more]
Pkn	3.409e-83	44.24	gene:FBgn0020621 transcript:FBtr0088601	[more]
Pkn	4.382e-83	44.24	gene:FBgn0020621 transcript:FBtr0088603	[more]
Pkn	4.810e-83	44.24	gene:FBgn0020621 transcript:FBtr0301511	[more]

BLAST of Protein kinase N2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pkn3	2.878e-96	47.96	protein kinase N3 [Source:ZFIN;Acc:ZDB-GENE-030131...	[more]
pkn3	4.160e-96	47.96	protein kinase N3 [Source:ZFIN;Acc:ZDB-GENE-030131...	[more]
pkn3	4.160e-96	47.96	protein kinase N3 [Source:ZFIN;Acc:ZDB-GENE-030131...	[more]
BX321890.2	4.592e-96	47.96	protein kinase N3 [Source:NCBI gene;Acc:323182]	[more]
PKN2	1.309e-86	45.45	zgc:153916 [Source:NCBI gene;Acc:567134]	[more]

BLAST of Protein kinase N2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
jph3	4.770e-91	46.38	junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974]	[more]
jph3	7.205e-91	46.38	junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974]	[more]
jph3	9.792e-91	46.38	junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974]	[more]
jph3	1.355e-90	46.38	junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974]	[more]
jph3	1.457e-90	47.00	junctophilin 3 [Source:Xenbase;Acc:XB-GENE-987974]	[more]

BLAST of Protein kinase N2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pkn1	8.952e-87	46.15	protein kinase N1 [Source:MGI Symbol;Acc:MGI:10802...	[more]
Pkn1	9.811e-87	46.15	protein kinase N1 [Source:MGI Symbol;Acc:MGI:10802...	[more]
Pkn2	8.940e-86	45.82	protein kinase N2 [Source:MGI Symbol;Acc:MGI:10921...	[more]
Pkn2	3.278e-85	45.82	protein kinase N2 [Source:MGI Symbol;Acc:MGI:10921...	[more]
Pkn2	3.329e-85	45.82	protein kinase N2 [Source:MGI Symbol;Acc:MGI:10921...	[more]

BLAST of Protein kinase N2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q63433\|PKN1_RAT	9.611e-87	46.15	Serine/threonine-protein kinase N1 OS=Rattus norve...	[more]
sp\|P70268\|PKN1_MOUSE	6.262e-86	46.15	Serine/threonine-protein kinase N1 OS=Mus musculus...	[more]
sp\|A7MBL8\|PKN2_DANRE	8.317e-86	45.45	Serine/threonine-protein kinase N2 OS=Danio rerio ...	[more]
sp\|A1A4I4\|PKN1_BOVIN	1.538e-85	45.85	Serine/threonine-protein kinase N1 OS=Bos taurus O...	[more]
sp\|Q16513\|PKN2_HUMAN	2.984e-85	46.75	Serine/threonine-protein kinase N2 OS=Homo sapiens...	[more]

BLAST of Protein kinase N2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5C6NIS9	5.638e-97	46.47	Non-specific serine/threonine protein kinase OS=Ta...	[more]
A0A3Q2ZNH1	9.298e-97	49.19	Non-specific serine/threonine protein kinase OS=Kr...	[more]
A0A3Q1CAR4	1.049e-95	46.77	Non-specific serine/threonine protein kinase OS=Am...	[more]
A0A1A8IK28	2.041e-95	50.00	Protein kinase N3 (Fragment) OS=Nothobranchius kuh...	[more]
A0A1A8KCJ3	3.979e-95	50.51	Protein kinase N3 (Fragment) OS=Nothobranchius kuh...	[more]

BLAST of Protein kinase N2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pkn3	1.125e-96	46.65	protein kinase N3 [Source:ZFIN;Acc:ZDB-GENE-030131...	[more]
pkn2	6.600e-88	45.24	serine/threonine-protein kinase N2 [Source:NCBI ge...	[more]
zgc:153916	1.701e-87	44.51	serine/threonine-protein kinase N2 [Source:NCBI ge...	[more]
pkn1a	2.025e-87	48.33	protein kinase N1a [Source:ZFIN;Acc:ZDB-GENE-06120...	[more]
pkn1b	4.384e-87	46.46	protein kinase N1b [Source:ZFIN;Acc:ZDB-GENE-07042...	[more]

BLAST of Protein kinase N2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000008480.1	1.116e-70	38.80	pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1...	[more]
PRKCD	6.922e-70	41.81	protein kinase C delta [Source:HGNC Symbol;Acc:HGN...	[more]
PRKCD	7.818e-66	41.85	protein kinase C delta [Source:HGNC Symbol;Acc:HGN...	[more]
ENSPMAT00000006766.1	8.778e-64	37.75	pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 g...	[more]
ENSPMAT00000001814.1	6.742e-57	39.47	pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gen...	[more]

BLAST of Protein kinase N2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
PKC1	4.602e-82	43.75	Protein serine/threonine kinase; essential for cel...	[more]
YPK1	1.033e-65	39.40	S/T protein kinase; phosphorylates, downregulates ...	[more]
SCH9	3.435e-65	39.74	AGC family protein kinase; functional ortholog of ...	[more]
YPK2	1.053e-64	39.27	Protein kinase similar to S/T protein kinase Ypk1p...	[more]
KIN82	5.327e-56	38.89	Putative serine/threonine protein kinase; implicat...	[more]

BLAST of Protein kinase N2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO43312	3.646e-85	42.43	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35585	1.604e-71	43.91	Protein kinase C [Source:UniProtKB/TrEMBL;Acc:A7S...	[more]
EDO44938	1.522e-69	39.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31895	6.048e-68	40.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37800	1.754e-66	39.26	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein kinase N2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pkn3	3.766e-91	46.77	serine/threonine-protein kinase N2 [Source:NCBI ge...	[more]
pkn2	8.078e-89	45.76	protein kinase N2 [Source:NCBI gene;Acc:101158798]	[more]
pkn1a	3.481e-88	48.48	protein kinase N1 [Source:NCBI gene;Acc:101164700]	[more]
pkn1a	1.012e-87	48.48	protein kinase N1 [Source:NCBI gene;Acc:101164700]	[more]
pkn1a	2.495e-87	48.48	protein kinase N1 [Source:NCBI gene;Acc:101164700]	[more]

BLAST of Protein kinase N2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000014536.1	0.000e+0	95.71	SMESG000014536.1	[more]
SMESG000014533.1	0.000e+0	95.44	SMESG000014533.1	[more]
SMESG000014536.1	0.000e+0	97.58	SMESG000014536.1	[more]
SMESG000065035.1	1.249e-80	47.62	SMESG000065035.1	[more]
SMESG000065035.1	1.255e-80	47.62	SMESG000065035.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30005823 ID=SMED30005823|Name=Protein kinase N2|organism=Schmidtea mediterranea sexual|type=transcript|length=3674bp
ATCTATATAAATCTTATATGACATCAATCTAATAAATATGAACGAGGCTG
AAGCTAAAACCAAGAACTTAAATGTACTGAAAAGTCAAATGGTTGATGTC
ATTGATAGTCTTAGACTGAACCATGCAGTTCATGAATTATTACCTTTGTT
AAATTTGCTACAAACCTTAGAAAACAATATCACTAATATTAATTCATTAG
ATTTCCAAAGCTGGAATACTTTAAATGTATTAGAGATGAATCACAAATTG
GGATTTGATAAGATTAATCTCACTCAAAAAATGTATTTCCTATTCAATAG
AATACATATCGAAAGTGCTTATATTTCATCTTTGAACAAGTCTTTTGTGT
ATGGGCTAAAGATAAAATCCAATAAGAAAGACAATGAAAAGCTAAATAAT
TTGCGACTGTATTCCGTTGAAAAGAAGAAATTATTTGCAGTTTCATTGAA
ACTGTTGCTACAGGAAAATTTATGTATGAACACTGCTGGAATGACTCTGG
AAAGAATAACCGACTTGCTTTTGGAGAACCTTGATAATGGAATAATGAAC
ATTTATGATTACATTTACCAGGAATGTAGCATTTGCAATAAGAATCACGA
AACTTGCCAACTGGAATCGGGACCGTTCTGCTTCTGTAGGTTGAAGTCTC
TCAACATAAACGAAAGCCAGCACTATTCAGGAATAATAAAATTCAAATTT
TGCTCATTTATGGGAATGTACTCGACAAGTTATCTGAAAGAAATCCTTAT
AAACAACGCACCAAGATTGGTAGATAACCAATTCAAGAGCGAATATAACA
CAAAGACCAAACGCCGTTGCGAAGTCGTTATAAAAGAACAAATAGTTTGT
TCTGATTGGACAACTGGTCCATTGATGATTTCTGGGGAGTTCGAAGTGTA
CAATGCCAAGGAAATTGAAGTTCAAGTTTGGGAGGATCCTAAAGAAATCG
GCGAAACGAAACATCTCGTTGCAGTCGCTGTCGTTTCTTTGCAAGCGTTG
ATCGAGAACAAACACCATTCGAATTCAATCAACATCTCGATGGAACCCGA
CGGTTTCATGACAGGCCTGGTGAAATATACCCCGATCAAAAGATCGATCT
CGGAAAATCCAGAATTGAACAAAGAAAACCGACCGCTTTTACGCAAAATC
GGAGTCAAGCGCAGAATGAATATCATGGCTAAACTCACCGGGCACCGCTT
GGCACGTCATGTCGAGGCTCATATTCCCGTATCGTTATGGCTAGATTGGT
TCCAGAACCATGTCGACAGGCTGGCCATCCCGGTTGATAGCAACAGGAAC
GAACCGGAACAGAAGGAAAATAAGATCTCAGGCCTGTGCAGAATGGTCAG
ACGGTTTGTCATTAAAAGCTTCGGTTTGAACAATAAAAAACTTTTGATTA
CTCCTTGCAAAAGTCCATTGGTGAACAAAATAGCCAATGAAAGTTATCGA
CAGATTTCTAAGTCACCAATGCCAAACCGAGTGCCCAAAACTCCGAAATT
CAATCAGACCAATCCCAGGGCTATTTGTAAATTTAATCATCCTAAAGAGA
TCCGATTTGCAGACCAGGATTCTGTGTCGGCTATGAACGAGACATCGGAA
TGTCAATCAGAATTCATGATTTCCACCCCTCTCAAAACCAAAAGTTCAAT
CTCAAATGACCGTACTCCGTTTTTCGAAGCCAAGAAAAATAAGCTCGACA
ATCTGATGTCACCTATACACCCGATTAATCGCAAAACACCCCAGAGACTC
ACTACTTATTATAATGAACAAATAAATCCTCATATAAACGATATTCTCAG
AGCTACCACAGGCTTTATGGCCGATTGCTCGGTGACAAGGAGCAACATAA
ATTTAACCGATATCAATGAATTTGATTCAACTCGAATGACAAAATGCAAC
TCCATAAACAACTCTAAAACCAAACTCGACGATAGTGATGAACCGAGAGA
TATGAGACAAGCAACAATTTGCCACAAGAGCATTTTACAATCACCTTTTC
CACTGGACTCTCAATATGATTTCATTCCAAACTCATGTAGATCTGTGTCG
AGGAGTATGATCTCGGCGAGCACCCATTCCAAGCATTGCAATAACATTTC
CCAGGCATCGACAAAGACCAATCAGACAGCAGATAAGTGCGTTCATCATG
ATTGGGATTCGTGTTGTTATGATGATTCATCGTATCTTAGTGAGAAGAAC
ATCACTAAGAACTCGTTTAAGCAAGGGATCGATATCAGATGTCTGGAATC
TTCCATTGGTGCCAGTGATCATGGTAGTTTCGATGGTCATGGGGATATTG
AGACTGAGGTCGCTAATGGCGATGGAGAGGGGGAGCGGGAGGAAGACGAG
GAGGACATTGATATCGATAACAACTCGTTCAATGGTACATTTAGATCTCG
ATCCGTTTGCCACCAAGTTCTCGATAAGTTGGAATTGTTGACTGTGCTCG
GTCAAGGACATTTCGGCAAAGTCCTGCTTGCGAAAGTCATAGAAACGAAA
AGCGTCTGTGCAATTAAAAGCATCCAGAAAGCAAGAGCAGCCACAGATAC
GGAATATGATAGCCTGTTTGCCGAGAGGGAGATTTTAATTTTGATCAGGA
AACACAATAATCCGTTTCTCATCAATTTGATTGGATGTTTTCAATCAGAG
CGTCACTTATTCTTCGCCCTAGAATATGTGGCCGGGGGAGATTTCATGGG
CCACGTGCATAAAAGTCCATTCATTGAAGAGGATGCGAGATTTTATATAA
GTTGTATTGTCCTAGCATTTGAGTTCTTGCACGACCAAGATATTATATAC
AGAGATCTGAAACTGGACAATGTCCTAATGGACATACACGGCTATGCGAA
ACTAACAGATTTCGGCCTCAGCAAACCAAACATGAAGTGGGATACTAAAA
CGACAACATTTTGTGGAACTCCAGAGTTTCTCGCTCCGGAAATCATCGAA
GAGAAAAATTATACTCGAGTCATTGATTGGTGGGCTTTGGGAGTTCTGCT
TTATGAAATGATTCTCGGGGAGTCTCCATTTCCCGGCGATGACGACAGGG
AGATATTCTCGATGATTTTATCGACTACTCCTAACATTAAAAGTCTTTCT
CCAGAATCTACATCTCTCATCAAGCGGTTATTAAAAAGAGATCCCGAAAA
GCGACTCGGATACGGGTGTGAAGGGACTCGTAAAGTGAAAGAACATTCGT
TTTTTGCTTCCATAGACTGGAATAAGTTATATTCTCGACAGCTCGTGCCT
CCTTTCATTCCTAAATTGGATGACGTCACCGATACTCAGTATTTCGAAAG
CGAATTCACTAATCAGCCAGTGACCATTGAGCATGACGACGAGGAGGTAG
ATTCAGAATTCGATGACGAGCTATTCAGGAATTTCGACACGGATTTGCAG
TGGCAATGATGATAACAATAAAAATGATAATATTATATTGCTGAAATTTT
GCATTTTTTTTTCGTTTTTGATAACTATTATTAGTAATTTTCTAGTGTAA
TGTTATCTCGTCACTGATGTTCATATTACTGACAAATGTTATCCAATCGC
ATTACTTGCACCGGCCGCTAGTCTCCAGCCACATTTTGTAATGCTGCTTT
TAATAACAATAAACATTTTTATGTTTACCCGCACACTTTTTATATCATTC
TCATCATTTCCGCAGATCGGAAGA

protein sequence of SMED30005823-orf-1

>SMED30005823-orf-1 ID=SMED30005823-orf-1|Name=SMED30005823-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1124bp
MNEAEAKTKNLNVLKSQMVDVIDSLRLNHAVHELLPLLNLLQTLENNITN
INSLDFQSWNTLNVLEMNHKLGFDKINLTQKMYFLFNRIHIESAYISSLN
KSFVYGLKIKSNKKDNEKLNNLRLYSVEKKKLFAVSLKLLLQENLCMNTA
GMTLERITDLLLENLDNGIMNIYDYIYQECSICNKNHETCQLESGPFCFC
RLKSLNINESQHYSGIIKFKFCSFMGMYSTSYLKEILINNAPRLVDNQFK
SEYNTKTKRRCEVVIKEQIVCSDWTTGPLMISGEFEVYNAKEIEVQVWED
PKEIGETKHLVAVAVVSLQALIENKHHSNSINISMEPDGFMTGLVKYTPI
KRSISENPELNKENRPLLRKIGVKRRMNIMAKLTGHRLARHVEAHIPVSL
WLDWFQNHVDRLAIPVDSNRNEPEQKENKISGLCRMVRRFVIKSFGLNNK
KLLITPCKSPLVNKIANESYRQISKSPMPNRVPKTPKFNQTNPRAICKFN
HPKEIRFADQDSVSAMNETSECQSEFMISTPLKTKSSISNDRTPFFEAKK
NKLDNLMSPIHPINRKTPQRLTTYYNEQINPHINDILRATTGFMADCSVT
RSNINLTDINEFDSTRMTKCNSINNSKTKLDDSDEPRDMRQATICHKSIL
QSPFPLDSQYDFIPNSCRSVSRSMISASTHSKHCNNISQASTKTNQTADK
CVHHDWDSCCYDDSSYLSEKNITKNSFKQGIDIRCLESSIGASDHGSFDG
HGDIETEVANGDGEGEREEDEEDIDIDNNSFNGTFRSRSVCHQVLDKLEL
LTVLGQGHFGKVLLAKVIETKSVCAIKSIQKARAATDTEYDSLFAEREIL
ILIRKHNNPFLINLIGCFQSERHLFFALEYVAGGDFMGHVHKSPFIEEDA
RFYISCIVLAFEFLHDQDIIYRDLKLDNVLMDIHGYAKLTDFGLSKPNMK
WDTKTTTFCGTPEFLAPEIIEEKNYTRVIDWWALGVLLYEMILGESPFPG
DDDREIFSMILSTTPNIKSLSPESTSLIKRLLKRDPEKRLGYGCEGTRKV
KEHSFFASIDWNKLYSRQLVPPFIPKLDDVTDTQYFESEFTNQPVTIEHD
DEEVDSEFDDELFRNFDTDLQWQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0017049	GTP-Rho binding
GO:0005524	ATP binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0000166	nucleotide binding
GO:0004697	protein kinase C activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0046872	metal ion binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000429	neoblast
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR000719	Prot_kinase_dom
IPR000961	AGC-kinase_C
IPR017441	Protein_kinase_ATP_BS
IPR008271	Ser/Thr_kinase_AS
IPR011009	Kinase-like_dom_sf

Vocabulary: **biological process**
Term	Definition
GO:0006468	protein phosphorylation
GO:0007165	signal transduction
GO:0016310	phosphorylation
GO:0035556	intracellular signal transduction

Vocabulary: **cellular component**
Term	Definition
GO:0005622	intracellular

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000961	AGC-kinase, C-terminal	SMART	SM00133	pkinase_C_6	coord: 1063..1121 e-value: 8.5E-12 score: 55.2
IPR000961	AGC-kinase, C-terminal	PROSITE	PS51285	AGC_KINASE_CTER	coord: 1063..1129 score: 14.859
IPR000719	Protein kinase domain	SMART	SM00220	serkin_6	coord: 804..1062 e-value: 6.4E-85 score: 298.1
IPR000719	Protein kinase domain	PFAM	PF00069	Pkinase	coord: 806..1062 e-value: 1.5E-61 score: 208.1
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 804..1062 score: 45.658
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 890..1093 e-value: 9.4E-111 score: 371.8
None	No IPR available	GENE3D	G3DSA:3.30.200.20		coord: 802..1112 e-value: 9.4E-111 score: 371.8
None	No IPR available	PANTHER	PTHR24356	SERINE/THREONINE-PROTEIN KINASE	coord: 296..1128
None	No IPR available	PANTHER	PTHR24356:SF210	SERINE/THREONINE-PROTEIN KINASE N	coord: 296..1128
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 810..833
IPR008271	Serine/threonine-protein kinase, active site	PROSITE	PS00108	PROTEIN_KINASE_ST	coord: 925..937
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 800..1106