vault protein inter alpha trypsin-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30005772 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 34
Homology
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Human
Match: VWA5A (von Willebrand factor A domain containing 5A [Source:HGNC Symbol;Acc:HGNC:6658]) HSP 1 Score: 270.781 bits (691), Expect = 2.536e-77 Identity = 184/605 (30.41%), Postives = 298/605 (49.26%), Query Frame = 2
Query: 59 YDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDRE---------VFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM-----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
+ + LKS+SV NI ++ + Y+N+ E F FP++ + VY FEALV GKKI+ ++ +A+ YE A +GH A ++E ++S DVF C +GN S+A + LK+ EL P+ ++ RF +LP +L PRY +++G + + V + Y + A I+ IE V S + +KTSA+V L + + +D+++ I Y + PSVV E+G + G AMV F P +N C E + ++DRSGSM+ I AKE L++ LKSLP+ C F IYGFGS ++ F +S Y+ ++ AL K + A+ GGTE++ PL+++Y + F+ TDG V++ V K VR + + R F+ GIG+G S SL+ +A+A G S F+ + + + L ++ V D L WH P +S IF L ++ + G +G+V +K TL G + V+F + + D +HRL AK + + + KKD ++LSL+ +++ +T F+AI+++
Sbjct: 11 HREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQEL---PLEADGALRF--VLPAVLNPRY---QFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPN------MKPGHLMGDPSAMVSFYPNIPEDQPSNTCG-EFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPV-VEDVSLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKP-----DVNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKE 594
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Human
Match: VWA5A (von Willebrand factor A domain containing 5A [Source:HGNC Symbol;Acc:HGNC:6658]) HSP 1 Score: 270.781 bits (691), Expect = 2.536e-77 Identity = 184/605 (30.41%), Postives = 298/605 (49.26%), Query Frame = 2
Query: 59 YDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDRE---------VFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM-----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
+ + LKS+SV NI ++ + Y+N+ E F FP++ + VY FEALV GKKI+ ++ +A+ YE A +GH A ++E ++S DVF C +GN S+A + LK+ EL P+ ++ RF +LP +L PRY +++G + + V + Y + A I+ IE V S + +KTSA+V L + + +D+++ I Y + PSVV E+G + G AMV F P +N C E + ++DRSGSM+ I AKE L++ LKSLP+ C F IYGFGS ++ F +S Y+ ++ AL K + A+ GGTE++ PL+++Y + F+ TDG V++ V K VR + + R F+ GIG+G S SL+ +A+A G S F+ + + + L ++ V D L WH P +S IF L ++ + G +G+V +K TL G + V+F + + D +HRL AK + + + KKD ++LSL+ +++ +T F+AI+++
Sbjct: 11 HREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQEL---PLEADGALRF--VLPAVLNPRY---QFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPN------MKPGHLMGDPSAMVSFYPNIPEDQPSNTCG-EFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPV-VEDVSLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKP-----DVNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKE 594
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Human
Match: VWA5A (von Willebrand factor A domain containing 5A [Source:HGNC Symbol;Acc:HGNC:6658]) HSP 1 Score: 202.986 bits (515), Expect = 1.681e-56 Identity = 139/431 (32.25%), Postives = 216/431 (50.12%), Query Frame = 2
Query: 32 TMFGLCPLK--YDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDRE---------VFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTR 1261
TM C L + + LKS+SV NI ++ + Y+N+ E F FP++ + VY FEALV GKKI+ ++ +A+ YE A +GH A ++E ++S DVF C +GN S+A + LK+ EL P+ ++ RF +LP +L PRY +++G + + V + Y + A I+ IE V S + +KTSA+V L + + +D+++ I Y + PSVV E+G + G AMV F P +N C E + ++DRSGSM+ I AKE L++ LKSLP+ C F IYGFGS ++ F +S Y+ ++ AL K + A+ GGTE++ PL+++Y + F+ TDG V++ V K VR + + R
Sbjct: 16 TMVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQEL---PLEADGALRF--VLPAVLNPRY---QFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPN------MKPGHLMGDPSAMVSFYPNIPEDQPSNTCG-EFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHR 431
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Human
Match: VWA5A (von Willebrand factor A domain containing 5A [Source:HGNC Symbol;Acc:HGNC:6658]) HSP 1 Score: 202.216 bits (513), Expect = 2.381e-56 Identity = 135/420 (32.14%), Postives = 212/420 (50.48%), Query Frame = 2
Query: 59 YDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDRE---------VFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTR 1261
+ + LKS+SV NI ++ + Y+N+ E F FP++ + VY FEALV GKKI+ ++ +A+ YE A +GH A ++E ++S DVF C +GN S+A + LK+ EL P+ ++ RF +LP +L PRY +++G + + V + Y + A I+ IE V S + +KTSA+V L + + +D+++ I Y + PSVV E+G + G AMV F P +N C E + ++DRSGSM+ I AKE L++ LKSLP+ C F IYGFGS ++ F +S Y+ ++ AL K + A+ GGTE++ PL+++Y + F+ TDG V++ V K VR + + R
Sbjct: 11 HREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQEL---PLEADGALRF--VLPAVLNPRY---QFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPN------MKPGHLMGDPSAMVSFYPNIPEDQPSNTCG-EFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHR 415
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Human
Match: VWA5A (von Willebrand factor A domain containing 5A [Source:HGNC Symbol;Acc:HGNC:6658]) HSP 1 Score: 202.216 bits (513), Expect = 2.381e-56 Identity = 135/420 (32.14%), Postives = 212/420 (50.48%), Query Frame = 2
Query: 59 YDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDRE---------VFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTR 1261
+ + LKS+SV NI ++ + Y+N+ E F FP++ + VY FEALV GKKI+ ++ +A+ YE A +GH A ++E ++S DVF C +GN S+A + LK+ EL P+ ++ RF +LP +L PRY +++G + + V + Y + A I+ IE V S + +KTSA+V L + + +D+++ I Y + PSVV E+G + G AMV F P +N C E + ++DRSGSM+ I AKE L++ LKSLP+ C F IYGFGS ++ F +S Y+ ++ AL K + A+ GGTE++ PL+++Y + F+ TDG V++ V K VR + + R
Sbjct: 11 HREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQEL---PLEADGALRF--VLPAVLNPRY---QFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPN------MKPGHLMGDPSAMVSFYPNIPEDQPSNTCG-EFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHR 415
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Zebrafish
Match: si:ch73-265h17.1 (si:ch73-265h17.1 [Source:ZFIN;Acc:ZDB-GENE-131121-358]) HSP 1 Score: 244.588 bits (623), Expect = 1.195e-69 Identity = 176/602 (29.24%), Postives = 299/602 (49.67%), Query Frame = 2
Query: 62 DQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGD-----REVFQVTNHYEYNF--KAVINGTKVIENVSSVNHTLE-IAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQC-KTEIVIVVDRSGSMRG---------SNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMK-SGDVIKCTLSGSANGEPVSFTTE--IRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEE--TLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
++ LKS+SV+ +++ ++S + Y N+ E LF FP+ + V +F A +G ++I+ ++ E AK+ Y+ A G A ++E++ DVF+ +G A + + + EL V+++ RF LP +L PRYTP AG E+ V Y+ ++ K I + S N TL+ + F ++ T A V+L + +D+++ + Y +PS V E G ++ GS + V M+ P+F +M++ + E V V+DRSGSM G I+ AK+ LL+ LKSLP+ C F IYGFGS+F+ F S YS ++ AL + A+ GTE+++PL +Y+ ++ R F+ TDG V N EV LV+ H S R F+ GIG+G S +L+ +A+ G G + F+ + + ME L A+ ++ ++W P+ V+ T I +F + + G G T+ + N +PVS I+ T+ + VHRL A+ I + ++ S E +L+ +++LS+Q + + +T F+ I++D
Sbjct: 11 NEPVPLKSISVEVRVQDHVASVSSTLQYVNEEQRPLEALFVFPLPADAAVCHFSAKIGEQEIVAELQDKETAKDQYDDAVSSGQQAFLLEESAESPDVFRLSVGCLSPGQNAAVTIIYITELA---VQADQSLRF--CLPAVLNPRYTP---AGSDAGIVSEISSVCGAVPYSLTLSVHVSSPKPISKLES-NCTLDPLVFLCSDHTQATVNLSPGHMFDRDVELFLYYQDTHQPSAVVEAGVAT------APSGSLMRNPVVMITLYPEFPEEVMSSMATQGEFVFVMDRSGSMDGMMHRGKEAQHRIESAKDTLLLLLKSLPMGCYFNIYGFGSEFESFFPKSVEYSQDTMDQALKRVMEMRADMCGTEILQPLTHIYSQPCIPEHPRQLFIFTDGEVGNTKEVLDLVKSHAHSHRCFSFGIGEGASTALITGLAREGSGHAQFITGRERMQPKAMESLRFALQPA-VSNISVDWTLPEGVTAETVSPPIDVLFQGQRTLIYAQLKGKSLGGSEGSVTVKYNLNSQPVSNQLHFCIKPTE---ETGLVVHRLAARTIIRSLEQKERSSAESKSLRSSIVELSVQAGVSSVHTAFIGINKD 593
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Zebrafish
Match: si:ch73-265h17.2 (si:ch73-265h17.2 [Source:ZFIN;Acc:ZDB-GENE-131120-39]) HSP 1 Score: 243.047 bits (619), Expect = 4.796e-69 Identity = 177/603 (29.35%), Postives = 302/603 (50.08%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN-----HYEYNFKAVINGTKVIENVSSVNHTLE-IAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQC-KTEIVIVVDRSGSM-----RGS----NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMK-SGDVIKCTLSGSANGEPVSFTTE--IRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEET----------LKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
LKS+SV+ +++ ++S + Y N+ E LF FP+ + V +F A +G ++I+ ++ E AK+ Y+ A G A ++E++ DVFK +G A + + + EL V+++ RF LP +L PRYTP E + V ++++ Y ++ K I + S N TL+ + F ++ T A V+L + +D+++ + Y +PS V E G ++ S + V M+ P+F M++ + E V V+DRSGSM RG I+ AK+ LL+ LKSLP+ C F IYGFGS+F+ F S Y+ + AL K + A+ GGTE+++PL +Y+ ++ R F+ TDG V N EV LV+ H +S R F+ GIG+G S +L+ +A+ G G + F+ ++ + VME L A+ + ++ ++W P+ V+ T I +F + + G G T+ + N +PV+ I+ T+ + VHRL A+ I + ++ S + T L+K ++ LS+Q + + +T F+ I++D
Sbjct: 17 LKSISVEVRVQDHVASVSSTLQYVNEEQRPLEALFVFPLPADAAVCHFSAKIGEQEIVAELQDKETAKDQYDDAVSSGQQAFLLEESAKSPDVFKLSVGCLLPGQNAAVTIIYVTELA---VQADQSLRF--CLPAVLNPRYTP-EGSDAGIVSEISSVCGAAPYSLTLSVHVSSPKPISKLES-NCTLDPLVFLRSDHTQATVNLSPGHMFDRDVELFLYYQDTHQPSAVVEAGVAT------APSDSLMRNPVVMISLYPEFPEEGMSSMANQGEFVFVMDRSGSMDWTMHRGKEAQHRIESAKDTLLLLLKSLPMGCYFNIYGFGSRFESFFPKSVEYNQDKMDQALKKVKEMRADMGGTEILQPLAHIYSQPCIPEHPRQLFIFTDGEVGNTKEVLDLVKSHARSHRCFSFGIGEGASTALITGLAREGSGHAQFITGSERMQPKVMESLRFALQPI-VSNISVDWTLPERVTAETISPPIDVLFQGQRTLIYAQLKGKNLGGSEGSVTVKYNLNSQPVTNQLHFCIKPTE---ETGLVVHRLAARTMIRSLEQKERSPDFTRKKIKRTLAKLRKTIVKLSVQAGVSSVHTAFIGINKD 602
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Zebrafish
Match: vwa5a (von Willebrand factor A domain containing 5A [Source:ZFIN;Acc:ZDB-GENE-040912-181]) HSP 1 Score: 215.312 bits (547), Expect = 2.513e-60 Identity = 146/476 (30.67%), Postives = 238/476 (50.00%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNH----YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNN-QCKTEIVIVVDRSGSM-------RGSN--IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSI 1462
LKS+SV +R +SS Y N+ E LF FP+ + F A VGG++I G ++ + A++ Y+ G ++E++ DVF+ +G P A + ++ EL + E LP +L PRYTP A V QV + Y + A + + I + S + F + T A+V L + + KD+++ + Y+ +PS V E G+++ GS + M+ P+F +++M++ E + +VD+SGSM G+ I+ A++ LL+ LKSLP+ C F IYGFGS F F S LYS+ ++ AL K + A+ GGTE+++PL+ +Y ++ R F+ TDG V N E+ LVR H+ S R F+ GIG+G S +L+ +AK G G + F+ + + VM+ L A+ + ++W P+ VS+
Sbjct: 17 LKSISVQLQVRGHVSSVRATLQYVNEEERPLEALFVFPLPAEAALCSFSATVGGQEIRGELRDKQTARDEYDDGVSAGRQVFLLEESDQSADVFRLSVGCLPAGGAATVSFTYSTELTV-----EEDGGLRYCLPAVLNPRYTP--AAAGAGVPQVCSASVIPYSLSLSADVRSSVPIARLDSSCALEPLQFLDPQHTHAQVSLSAGHRFDKDVELLLYYVDPHQPSAVLEAGAAT------APAGSLMADPLLMLSLYPEFPAAVMSSLTSHGEFIFLVDQSGSMDCPMHHGEGAQMRIESARDTLLLLLKSLPLGCYFNIYGFGSSFQAFFPQSVLYSEQTLQEALQRVKLMRADLGGTEILQPLQHIYRQACIPEHPRQLFIFTDGEVWNTRELLDLVRAHSSSHRCFSFGIGEGASTALITGMAKEGSGHAQFITGSDRMQPKVMQSLRFALQPA-VEELCVDWRLPEGVSV 478
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Zebrafish
Match: vwa5a (von Willebrand factor A domain containing 5A [Source:ZFIN;Acc:ZDB-GENE-040912-181]) HSP 1 Score: 216.083 bits (549), Expect = 2.616e-58 Identity = 149/506 (29.45%), Postives = 247/506 (48.81%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNH----YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNN-QCKTEIVIVVDRSGSM-------RGSN--IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDV 1552
LKS+SV +R +SS Y N+ E LF FP+ + F A VGG++I G ++ + A++ Y+ G ++E++ DVF+ +G P A + ++ EL + E LP +L PRYTP A V QV + Y + A + + I + S + F + T A+V L + + KD+++ + Y+ +PS V E G+++ GS + M+ P+F +++M++ E + +VD+SGSM G+ I+ A++ LL+ LKSLP+ C F IYGFGS F F S LYS+ ++ AL K + A+ GGTE+++PL+ +Y ++ R F+ TDG V N E+ LVR H+ S R F+ GIG+G S +L+ +AK G G + F+ + + VM+ L A+ + ++W P+ VS+ + +F + + G + +V
Sbjct: 17 LKSISVQLQVRGHVSSVRATLQYVNEEERPLEALFVFPLPAEAALCSFSATVGGQEIRGELRDKQTARDEYDDGVSAGRQVFLLEESDQSADVFRLSVGCLPAGGAATVSFTYSTELTV-----EEDGGLRYCLPAVLNPRYTP--AAAGAGVPQVCSASVIPYSLSLSADVRSSVPIARLDSSCALEPLQFLDPQHTHAQVSLSAGHRFDKDVELLLYYVDPHQPSAVLEAGAAT------APAGSLMADPLLMLSLYPEFPAAVMSSLTSHGEFIFLVDQSGSMDCPMHHGEGAQMRIESARDTLLLLLKSLPLGCYFNIYGFGSSFQAFFPQSVLYSEQTLQEALQRVKLMRADLGGTEILQPLQHIYRQACIPEHPRQLFIFTDGEVWNTRELLDLVRAHSSSHRCFSFGIGEGASTALITGMAKEGSGHAQFITGSDRMQPKVMQSLRFALQPA-VEELCVDWRLPEGVSVELLSPPVRSLFQGQRALLYGRLRGQQRSEV 508
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Zebrafish
Match: vwa5b2 (von Willebrand factor A domain containing 5B2 [Source:ZFIN;Acc:ZDB-GENE-070912-216]) HSP 1 Score: 122.094 bits (305), Expect = 1.275e-27 Identity = 90/365 (24.66%), Postives = 169/365 (46.30%), Query Frame = 2
Query: 554 YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVH--LKSKYDGTKDLDININYLAMKEPSVVYEVGSSS--------------PLYSGKDAQGS--------FYHSD-----VAMVKFLPKFDSSLMN-NQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGI--ALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCM---INGMKS 1543
Y+ +F+ ++ G ++ + S H L + + K+++ + L ++ + ++I I +L P V+ E G + + K+A+ YH D V M+ F P S Q E++ ++D S +M NI++ KE +L+ +KSLP I G S +FN S+ +D S+ + AL + + L ++ G L L +Y + R F++ DGN+SN V +LVR++ + R F +G+G L+ +AK G + F+ + L +++ L A+ V TD +++W+ P +V + +P IP ++ L +C ++G+K+
Sbjct: 231 YQLSFQLLVRGACLLAGLESPTHALRADADPSAKSASATYITLAEEHQCDRHVEI-ILHLKSHSPLVILERGRLTFREYEQQIRARRDFIRCARKEAESEKRLEFVRRRYHKDLLLNPVLMLNFCPDLLSEPTELQQASRELIFLIDNSNTMTQHNINKIKEGMLVAIKSLPTRTMLNIAGICSTVRPLFNTSKTCTDVSVTVTQALEFIQKLRSDHGAVNLWSALSWVYRQPVHRSCPRQLFIIMDGNLSNVGRVIELVRRNACNVRCFGLGLGPQACRRLLQGIAKVTGGSTDFLSEEERLQPKLIKCLKKALEPV-LTDVRIDWYVPDNVEALLSPNEIPSLYPGNCLIGYCTLYDVSGLKA 593
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Xenopus
Match: gzma (granzyme A [Source:Xenbase;Acc:XB-GENE-482759]) HSP 1 Score: 254.988 bits (650), Expect = 1.076e-71 Identity = 187/661 (28.29%), Postives = 317/661 (47.96%), Query Frame = 2
Query: 26 ITTMFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN------HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVA-MVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMR-GSN--------IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTCITDDGSSTDDVRHVCSTSSTSSNEMFCIWPYVFSACSTSP 1945
+ FGL + Q L+ +SV+ ++ ++ YKN + E +F FP++ + VY FEA V GK I+ +E E+A Y A KG A +++++ S D+F C +GN P EA++ L F EL P+ ++ RF +LP +L PRYTP ++ + QV Y + A I + S + + + +++KT+A+V L + +D+++ Y+ + +PSV E G DA+ +D A M++F P F ++ E + ++DRSGSM G N I+ AKE L++ LKSLP+ C F I GFGS+F+ F ++ Y+ S+ A+ ++AN GGTE+++PL+ +Y + + D+ R F+ TDG V N +V + V+++ + R F GIG+G S SL+ +++A G F+ + + V++ L A+ + L+W P + V K IF + + + G K G+V ++ + F ++ E +HRL AK I+E+ S E +KK +++ S Q +++ T FVA++++ I D + H C MFC+ P AC+ +P
Sbjct: 1 MAPFFGLIIVCSRQPVPLRGISVEVQVKGFVADVCATLRYKNTEEKPIEAIFVFPLDQDSAVYSFEATVEGKTIVAELQEREQATKTYGEAISKGQQAFLLQEDKSSGDIFSCSVGNLPPGQEAEVKLSFVQEL---PLEADGAVRF--VLPAVLNPRYTPKDHE-ESITAQVPRVPIGQIPYTLDLTAHFQSAYGISKIQSNCNISPVEYTDSDKTAAKVSLAQGHKFERDVELLAYYMDVNKPSVAVEAGLP-------DAKADTLMADPAVMLQFYPSFPTT-QEQSNSGEFLFLMDRSGSMECGMNSEPNAPQRIESAKETLVLLLKSLPLGCYFNIIGFGSRFEFFFPETIEYTQESMDEAVKKVTQMEANMGGTEILQPLKKIYKTAVRPDHPRQLFVFTDGEVGNTKQVIEEVQRNAHNHRCFAFGIGEGASTSLIKGISRAAGGTCEFITGKERMQPKVLKALKNALQPT-VKEISLKWTLPPGMESVLLSKPPSNIFQGHRAIVYAQLKGKVTPGKEGEVSLEYKFKDENFRNSIKFPFKVEKV-----ERPTIHRLGAKALISELENGANSESEEVKKRIVESSTQSGVISSLTAFVAVNKETKAPVQGPPIRRDIPTPGMYLHTCY--------MFCLLPMRPMACNMAP 633
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Xenopus
Match: gzma (granzyme A [Source:Xenbase;Acc:XB-GENE-482759]) HSP 1 Score: 248.825 bits (634), Expect = 1.226e-69 Identity = 187/651 (28.73%), Postives = 316/651 (48.54%), Query Frame = 2
Query: 26 ITTMFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN------HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVA-MVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMR-GSN--------IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD--AP--GEPLVTCITDDGSSTDDVRHVCSTSSTSSNEMF 1903
+ FGL + Q L+ +SV+ ++ ++ YKN + E +F FP++ + VY FEA V GK I+ +E E+A Y A KG A +++++ S D+F C +GN P EA++ L F EL P+ ++ RF +LP +L PRYTP ++ + QV Y + A I + S + + + +++KT+A+V L + +D+++ Y+ + +PSV E G DA+ +D A M++F P F ++ E + ++DRSGSM G N I+ AKE L++ LKSLP+ C F I GFGS+F+ F ++ Y+ S+ A+ ++AN GGTE+++PL+ +Y + + D+ R F+ TDG V N +V + V+++ + R F GIG+G S SL+ +++A G F+ + + V++ L A+ + L+W P + V K IF + + + G K G+V ++ + F ++ E +HRL AK I+E+ S E +KK +++ S Q +++ T FVA++++ AP G P+ I G CS+ + S MF
Sbjct: 1 MAPFFGLIIVCSRQPVPLRGISVEVQVKGFVADVCATLRYKNTEEKPIEAIFVFPLDQDSAVYSFEATVEGKTIVAELQEREQATKTYGEAISKGQQAFLLQEDKSSGDIFSCSVGNLPPGQEAEVKLSFVQEL---PLEADGAVRF--VLPAVLNPRYTPKDHE-ESITAQVPRVPIGQIPYTLDLTAHFQSAYGISKIQSNCNISPVEYTDSDKTAAKVSLAQGHKFERDVELLAYYMDVNKPSVAVEAGLP-------DAKADTLMADPAVMLQFYPSFPTT-QEQSNSGEFLFLMDRSGSMECGMNSEPNAPQRIESAKETLVLLLKSLPLGCYFNIIGFGSRFEFFFPETIEYTQESMDEAVKKVTQMEANMGGTEILQPLKKIYKTAVRPDHPRQLFVFTDGEVGNTKQVIEEVQRNAHNHRCFAFGIGEGASTSLIKGISRAAGGTCEFITGKERMQPKVLKALKNALQPT-VKEISLKWTLPPGMESVLLSKPPSNIFQGHRAIVYAQLKGKIDEGKEGEVSLEYKFKDENFRNSIKFPFKVEKV-----ERPTIHRLGAKALISELENGANSESEEVKKRIVESSTQSGVISSLTAFVAVNKETKAPVQGPPIRRDIPTPGMYLHTSVSKCSSIFSFSGLMF 631
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Xenopus
Match: gzma (granzyme A [Source:Xenbase;Acc:XB-GENE-482759]) HSP 1 Score: 247.669 bits (631), Expect = 2.117e-69 Identity = 183/662 (27.64%), Postives = 315/662 (47.58%), Query Frame = 2
Query: 26 ITTMFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN------HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVA-MVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMR-GSN--------IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTCITDDGSSTDDVRHVCSTSSTSSNEMFCIWPYVFSACSTSPI 1948
+ FGL + Q L+ +SV+ ++ ++ YKN + E +F FP++ + VY FEA V GK I+ +E E+A Y A KG A +++++ S D+F C +GN P EA++ L F EL P+ ++ RF +LP +L PRYTP ++ + QV Y + A I + S + + + +++KT+A+V L + +D+++ Y+ + +PSV E G DA+ +D A M++F P F ++ E + ++DRSGSM G N I+ AKE L++ LKSLP+ C F I GFGS+F+ F ++ Y+ S+ A+ ++AN GGTE+++PL+ +Y + + D+ R F+ TDG V N +V + V+++ + R F GIG+G S SL+ +++A G F+ + + V++ L A+ + L+W P + V K IF + + + G K G+V ++ + F ++ E +HRL AK I+E+ S E +KK +++ S Q +++ T FVA++++ I D + H C + + + F A +P+
Sbjct: 1 MAPFFGLIIVCSRQPVPLRGISVEVQVKGFVADVCATLRYKNTEEKPIEAIFVFPLDQDSAVYSFEATVEGKTIVAELQEREQATKTYGEAISKGQQAFLLQEDKSSGDIFSCSVGNLPPGQEAEVKLSFVQEL---PLEADGAVRF--VLPAVLNPRYTPKDHE-ESITAQVPRVPIGQIPYTLDLTAHFQSAYGISKIQSNCNISPVEYTDSDKTAAKVSLAQGHKFERDVELLAYYMDVNKPSVAVEAGLP-------DAKADTLMADPAVMLQFYPSFPTT-QEQSNSGEFLFLMDRSGSMECGMNSEPNAPQRIESAKETLVLLLKSLPLGCYFNIIGFGSRFEFFFPETIEYTQESMDEAVKKVTQMEANMGGTEILQPLKKIYKTAVRPDHPRQLFVFTDGEVGNTKQVIEEVQRNAHNHRCFAFGIGEGASTSLIKGISRAAGGTCEFITGKERMQPKVLKALKNALQPT-VKEISLKWTLPPGMESVLLSKPPSNIFQGHRAIVYAQLKGKVTPGKEGEVSLEYKFKDENFRNSIKFPFKVEKV-----ERPTIHRLGAKALISELENGANSESEEVKKRIVESSTQSGVISSLTAFVAVNKETKAPVQGPPIRRDIPTPGMYLHTCYMFFQHLHGLCVYMSFFFPAAKATPV 642
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Xenopus
Match: gzma (granzyme A [Source:Xenbase;Acc:XB-GENE-482759]) HSP 1 Score: 247.669 bits (631), Expect = 4.485e-69 Identity = 182/630 (28.89%), Postives = 309/630 (49.05%), Query Frame = 2
Query: 26 ITTMFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN------HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVA-MVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMR-GSN--------IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD--AP--GEPLVTCITDDG 1840
+ FGL + Q L+ +SV+ ++ ++ YKN + E +F FP++ + VY FEA V GK I+ +E E+A Y A KG A +++++ S D+F C +GN P EA++ L F EL P+ ++ RF +LP +L PRYTP ++ + QV Y + A I + S + + + +++KT+A+V L + +D+++ Y+ + +PSV E G DA+ +D A M++F P F ++ E + ++DRSGSM G N I+ AKE L++ LKSLP+ C F I GFGS+F+ F ++ Y+ S+ A+ ++AN GGTE+++PL+ +Y + + D+ R F+ TDG V N +V + V+++ + R F GIG+G S SL+ +++A G F+ + + V++ L A+ + L+W P + V K IF + + + G K G+V ++ + F ++ E +HRL AK I+E+ S E +KK +++ S Q +++ T FVA++++ AP G P+ I G
Sbjct: 1 MAPFFGLIIVCSRQPVPLRGISVEVQVKGFVADVCATLRYKNTEEKPIEAIFVFPLDQDSAVYSFEATVEGKTIVAELQEREQATKTYGEAISKGQQAFLLQEDKSSGDIFSCSVGNLPPGQEAEVKLSFVQEL---PLEADGAVRF--VLPAVLNPRYTPKDHE-ESITAQVPRVPIGQIPYTLDLTAHFQSAYGISKIQSNCNISPVEYTDSDKTAAKVSLAQGHKFERDVELLAYYMDVNKPSVAVEAGLP-------DAKADTLMADPAVMLQFYPSFPTT-QEQSNSGEFLFLMDRSGSMECGMNSEPNAPQRIESAKETLVLLLKSLPLGCYFNIIGFGSRFEFFFPETIEYTQESMDEAVKKVTQMEANMGGTEILQPLKKIYKTAVRPDHPRQLFVFTDGEVGNTKQVIEEVQRNAHNHRCFAFGIGEGASTSLIKGISRAAGGTCEFITGKERMQPKVLKALKNALQPT-VKEISLKWTLPPGMESVLLSKPPSNIFQGHRAIVYAQLKGKIDEGKEGEVSLEYKFKDENFRNSIKFPFKVEKV-----ERPTIHRLGAKALISELENGANSESEEVKKRIVESSTQSGVISSLTAFVAVNKETKAPVQGPPIRRDIPTPG 610
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Xenopus
Match: gzma (granzyme A [Source:Xenbase;Acc:XB-GENE-482759]) HSP 1 Score: 246.514 bits (628), Expect = 5.083e-69 Identity = 183/647 (28.28%), Postives = 315/647 (48.69%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN------HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVA-MVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMR-GSN--------IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM-KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD--AP--GEPLVTCITDDGSSTDDVRHVCSTSSTSSNEMFCIW-PYVFSACSTSPI 1948
L+ +SV+ ++ ++ YKN + E +F FP++ + VY FEA V GK I+ +E E+A Y A KG A +++++ S D+F C +GN P EA++ L F EL P+ ++ RF +LP +L PRYTP ++ + QV Y + A I + S + + + +++KT+A+V L + +D+++ Y+ + +PSV E G DA+ +D A M++F P F ++ E + ++DRSGSM G N I+ AKE L++ LKSLP+ C F I GFGS+F+ F ++ Y+ S+ A+ ++AN GGTE+++PL+ +Y + + D+ R F+ TDG V N +V + V+++ + R F GIG+G S SL+ +++A G F+ + + V++ L A+ + L+W P + V K IF + + + G K G+V ++ + F ++ E +HRL AK I+E+ S E +KK +++ S Q +++ T FVA++++ AP G P+ I G +H+ C++ + F A +P+
Sbjct: 12 LRGISVEVQVKGFVADVCATLRYKNTEEKPIEAIFVFPLDQDSAVYSFEATVEGKTIVAELQEREQATKTYGEAISKGQQAFLLQEDKSSGDIFSCSVGNLPPGQEAEVKLSFVQEL---PLEADGAVRF--VLPAVLNPRYTPKDHE-ESITAQVPRVPIGQIPYTLDLTAHFQSAYGISKIQSNCNISPVEYTDSDKTAAKVSLAQGHKFERDVELLAYYMDVNKPSVAVEAGLP-------DAKADTLMADPAVMLQFYPSFPTT-QEQSNSGEFLFLMDRSGSMECGMNSEPNAPQRIESAKETLVLLLKSLPLGCYFNIIGFGSRFEFFFPETIEYTQESMDEAVKKVTQMEANMGGTEILQPLKKIYKTAVRPDHPRQLFVFTDGEVGNTKQVIEEVQRNAHNHRCFAFGIGEGASTSLIKGISRAAGGTCEFITGKERMQPKVLKALKNALQPT-VKEISLKWTLPPGMESVLLSKPPSNIFQGHRAIVYAQLKGKGKEGEVSLEYKFKDENFRNSIKFPFKVEKV-----ERPTIHRLGAKALISELENGANSESEEVKKRIVESSTQSGVISSLTAFVAVNKETKAPVQGPPIRRDIPTPGMYLHTFQHLHG---------LCVYMSFFFPAAKATPV 629
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Mouse
Match: Vwa5a (von Willebrand factor A domain containing 5A [Source:MGI Symbol;Acc:MGI:1915026]) HSP 1 Score: 246.128 bits (627), Expect = 1.041e-68 Identity = 186/599 (31.05%), Postives = 299/599 (49.92%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGD------REVFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSI-VTAPKSIPPIFSDYFLTAFCMINGM-----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKIN--EMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
LK++SV +I +++ Y+N+ E F FP++ + VY FEALV GKKI+ ++ +A + YE A +GH A ++E++ DVF C +GN ++ + L++ EL P+ ++ R+ LLP IL PRY E + + + + + Y N A I IE V S I + +KTSA+V L + +D+++ I Y + PSV E+G L D S + AMV F P + C E V ++DRSGSM I+ AKE LL+ LKSLP+ C F IYGFGS ++K F +S Y+ ++ A+ K L AN GGTE++ PL ++Y + + F+ TDG VS+ V + V+ ++K R F+ GIG G S SL+ +A+ G +VF+ + + L A+ + L W P +S+ + +P+ + IF L + + G+ +G V +K L G + V+F+ + + D F +HRL AK I + Q S EE K+D++++SLQ +++ +T F+AI+++
Sbjct: 17 LKNISVTLSINEFVAAVVATLNYENEEKVPLEATFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKAHSEYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGAKVAVTLRYVQEL---PLETDGALRY--LLPAILNPRYQLSEQSANSCLNIQKPTVPLEDLPYTLNMTATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYNEVHSPSVAVEMGM---LDMKPD---SLMGAPSAMVSFYPDIPEVEASKAC-GEFVFLMDRSGSMDSPMSTENNSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEKFFPESVKYTQDTMEDAVKRVKALKANLGGTEILTPLCNIYKASSIPGHPLQLFVFTDGEVSDTFSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAVFITGKDRMQTKALGSLKFALQCA-VDNISLSWDLPPGLSVKMLSPEQL-TIFRGQRLIIYAQLTGLMPQVESTGAVCLKHILQGRSLENRVTFSLQPKAND-----NFTIHRLAAKSLIQTKDFGSQEASKEE--KEDVMNISLQSGVLSSFTAFIAINKE 594
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Mouse
Match: Vwa5a (von Willebrand factor A domain containing 5A [Source:MGI Symbol;Acc:MGI:1915026]) HSP 1 Score: 246.128 bits (627), Expect = 1.041e-68 Identity = 186/599 (31.05%), Postives = 299/599 (49.92%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGD------REVFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSI-VTAPKSIPPIFSDYFLTAFCMINGM-----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKIN--EMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
LK++SV +I +++ Y+N+ E F FP++ + VY FEALV GKKI+ ++ +A + YE A +GH A ++E++ DVF C +GN ++ + L++ EL P+ ++ R+ LLP IL PRY E + + + + + Y N A I IE V S I + +KTSA+V L + +D+++ I Y + PSV E+G L D S + AMV F P + C E V ++DRSGSM I+ AKE LL+ LKSLP+ C F IYGFGS ++K F +S Y+ ++ A+ K L AN GGTE++ PL ++Y + + F+ TDG VS+ V + V+ ++K R F+ GIG G S SL+ +A+ G +VF+ + + L A+ + L W P +S+ + +P+ + IF L + + G+ +G V +K L G + V+F+ + + D F +HRL AK I + Q S EE K+D++++SLQ +++ +T F+AI+++
Sbjct: 17 LKNISVTLSINEFVAAVVATLNYENEEKVPLEATFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKAHSEYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGAKVAVTLRYVQEL---PLETDGALRY--LLPAILNPRYQLSEQSANSCLNIQKPTVPLEDLPYTLNMTATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYNEVHSPSVAVEMGM---LDMKPD---SLMGAPSAMVSFYPDIPEVEASKAC-GEFVFLMDRSGSMDSPMSTENNSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEKFFPESVKYTQDTMEDAVKRVKALKANLGGTEILTPLCNIYKASSIPGHPLQLFVFTDGEVSDTFSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAVFITGKDRMQTKALGSLKFALQCA-VDNISLSWDLPPGLSVKMLSPEQL-TIFRGQRLIIYAQLTGLMPQVESTGAVCLKHILQGRSLENRVTFSLQPKAND-----NFTIHRLAAKSLIQTKDFGSQEASKEE--KEDVMNISLQSGVLSSFTAFIAINKE 594
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Mouse
Match: AW551984 (expressed sequence AW551984 [Source:MGI Symbol;Acc:MGI:2143322]) HSP 1 Score: 242.662 bits (618), Expect = 1.776e-67 Identity = 175/597 (29.31%), Postives = 285/597 (47.74%), Query Frame = 2
Query: 74 SLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN-------HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM-----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
+LKS++V +I + ++ + Y+N+ E F FP++ + VY FEA V GKKI+ ++ +A YE A G+ A ++E++ DVF C +GN S+ + L++ EL P+ + R+ +LP IL PRY + D + T Y + A I+ I + S I + NKTSA+V L + +D+++ I Y + PSV E+G SG+ + S + AMV F P +C E V ++DRS SM ID AKE L++ LKSLP+ C F IYGFG+ ++ F DS +Y+ ++ IA+ K L A+ GGTEL+ PL ++ + F+ TDG V V + V +K R F+ GIG+G S SL+ +A+ G + F+ + + + L ++ SV D L W+ P + IF L + ++ G +G+V + L G + E V+F+ + + D+ +HRL AK I + K+D++D+SL+ +++ +T FVAI+++
Sbjct: 16 ALKSIAVTLSINDFVAGVSATLNYENEEKSPLEAFFVFPMDEDSAVYSFEAFVDGKKIVAELQDKYQAHKRYEEALSGGYQAYLLEEDKCSRDVFCCNVGNLQPGSKVSLTLRYVQEL---PLEDDGALRY--VLPAILNPRYHLSDGREDSNLDMKTPIVPLEELPYTLSMVATISSQLGISTIQSNCPLNPIEYTGDNKTSAQVSLAEGHKFDRDVELLIFYRKVHSPSVAVEMG-----MSGRPSD-SLMGAPSAMVSFYPDIPEVETTTKC-GEFVFLMDRSRSMNSPMSSKDKSQLRIDAAKETLILLLKSLPMGCYFNIYGFGATHEEFFPDSVMYNQETMQIAVKKVKRLLADLGGTELLTPLRKIFRKPPIPGHPLQVFVFTDGEVVETFSVIREVMFQSKKHRCFSFGIGEGASTSLIKNLARVSGGTAEFITGNDRMQSKALRSLRRSLQSV-VEDVSLSWNLPPKMFAPMLSPEQTSIFRGQRLIIYSLLIGKIPKEEATGEVCLSYKLHGKSYEEKVTFSLQPKP-----DDNLTIHRLAAKSMIQSKDFGFKETSLMYKRDVLDISLESGVMSSFTAFVAINKE 594
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Mouse
Match: AW551984 (expressed sequence AW551984 [Source:MGI Symbol;Acc:MGI:2143322]) HSP 1 Score: 242.662 bits (618), Expect = 1.776e-67 Identity = 175/597 (29.31%), Postives = 285/597 (47.74%), Query Frame = 2
Query: 74 SLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN-------HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM-----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
+LKS++V +I + ++ + Y+N+ E F FP++ + VY FEA V GKKI+ ++ +A YE A G+ A ++E++ DVF C +GN S+ + L++ EL P+ + R+ +LP IL PRY + D + T Y + A I+ I + S I + NKTSA+V L + +D+++ I Y + PSV E+G SG+ + S + AMV F P +C E V ++DRS SM ID AKE L++ LKSLP+ C F IYGFG+ ++ F DS +Y+ ++ IA+ K L A+ GGTEL+ PL ++ + F+ TDG V V + V +K R F+ GIG+G S SL+ +A+ G + F+ + + + L ++ SV D L W+ P + IF L + ++ G +G+V + L G + E V+F+ + + D+ +HRL AK I + K+D++D+SL+ +++ +T FVAI+++
Sbjct: 16 ALKSIAVTLSINDFVAGVSATLNYENEEKSPLEAFFVFPMDEDSAVYSFEAFVDGKKIVAELQDKYQAHKRYEEALSGGYQAYLLEEDKCSRDVFCCNVGNLQPGSKVSLTLRYVQEL---PLEDDGALRY--VLPAILNPRYHLSDGREDSNLDMKTPIVPLEELPYTLSMVATISSQLGISTIQSNCPLNPIEYTGDNKTSAQVSLAEGHKFDRDVELLIFYRKVHSPSVAVEMG-----MSGRPSD-SLMGAPSAMVSFYPDIPEVETTTKC-GEFVFLMDRSRSMNSPMSSKDKSQLRIDAAKETLILLLKSLPMGCYFNIYGFGATHEEFFPDSVMYNQETMQIAVKKVKRLLADLGGTELLTPLRKIFRKPPIPGHPLQVFVFTDGEVVETFSVIREVMFQSKKHRCFSFGIGEGASTSLIKNLARVSGGTAEFITGNDRMQSKALRSLRRSLQSV-VEDVSLSWNLPPKMFAPMLSPEQTSIFRGQRLIIYSLLIGKIPKEEATGEVCLSYKLHGKSYEEKVTFSLQPKP-----DDNLTIHRLAAKSMIQSKDFGFKETSLMYKRDVLDISLESGVMSSFTAFVAINKE 594
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Mouse
Match: Vwa5b1 (von Willebrand factor A domain containing 5B1 [Source:MGI Symbol;Acc:MGI:1922968]) HSP 1 Score: 142.895 bits (359), Expect = 4.890e-34 Identity = 81/240 (33.75%), Postives = 128/240 (53.33%), Query Frame = 2
Query: 812 HSDVAMVKFLPKFDSSLMN-NQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMI 1528
H V M+ F P S N + E + ++DRS SM +NI KE +L+ LKSL C F I GFGS F VF S++Y++ ++ +A + + + A+ GGT ++ PL+ + L + RL FL+TDG+V+N +V +LVR H STR ++ GIG V LV +A G + F+ + L +++ L AM V +D +EW P+ + +P S +F L + ++
Sbjct: 328 HHSVIMLNFCPDLQSVQPNPRKAHGEFIFLIDRSNSMSKTNIQCIKEAMLVALKSLMPACFFNIIGFGSTFKAVFASSRIYNEENLTMACDCIQRMQADMGGTNMLSPLKWVLRQPLRRGHPRLLFLITDGSVNNTGKVLELVRNHASSTRCYSFGIGPTVCYRLVKGLASVSKGSAEFLMEGERLQPKMVKSLKKAMAPV-LSDVTVEWVFPETTEALISPVSTSSLFPGERLMGYGIV 566
BLAST of vault protein inter alpha trypsin-1 vs. UniProt/SwissProt
Match: sp|O00534|VMA5A_HUMAN (von Willebrand factor A domain-containing protein 5A OS=Homo sapiens OX=9606 GN=VWA5A PE=1 SV=2) HSP 1 Score: 270.781 bits (691), Expect = 1.218e-76 Identity = 184/605 (30.41%), Postives = 298/605 (49.26%), Query Frame = 2
Query: 59 YDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDRE---------VFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM-----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
+ + LKS+SV NI ++ + Y+N+ E F FP++ + VY FEALV GKKI+ ++ +A+ YE A +GH A ++E ++S DVF C +GN S+A + LK+ EL P+ ++ RF +LP +L PRY +++G + + V + Y + A I+ IE V S + +KTSA+V L + + +D+++ I Y + PSVV E+G + G AMV F P +N C E + ++DRSGSM+ I AKE L++ LKSLP+ C F IYGFGS ++ F +S Y+ ++ AL K + A+ GGTE++ PL+++Y + F+ TDG V++ V K VR + + R F+ GIG+G S SL+ +A+A G S F+ + + + L ++ V D L WH P +S IF L ++ + G +G+V +K TL G + V+F + + D +HRL AK + + + KKD ++LSL+ +++ +T F+AI+++
Sbjct: 11 HREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQEL---PLEADGALRF--VLPAVLNPRY---QFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPN------MKPGHLMGDPSAMVSFYPNIPEDQPSNTCG-EFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPV-VEDVSLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKP-----DVNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKE 594
BLAST of vault protein inter alpha trypsin-1 vs. UniProt/SwissProt
Match: sp|Q75WE7|VWA5A_RAT (von Willebrand factor A domain-containing protein 5A OS=Rattus norvegicus OX=10116 GN=Vwa5a PE=2 SV=1) HSP 1 Score: 263.462 bits (672), Expect = 9.818e-74 Identity = 185/602 (30.73%), Postives = 298/602 (49.50%), Query Frame = 2
Query: 65 QKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAG------DREVFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMING------MKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKIN--EMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
+K LKS+SV +I + +++ Y+N+ E +F FP++ + VY FEALV GKKI+ ++ +A + YE A +GH A ++E++ DVF C +GN ++ + L++ EL P+ S+ R+ LLP +L PRY E + + + + Y + A I IE V S I + +KTSA+V L + +D+++ I Y + PSV E G + S + AMV F P + C E V ++DRSGSM+ I+ AKE LL+ LKSLP+ C F IYGFGS +++ F +S Y+ +I A+ K LDA+ GGTE++ PL ++Y + + F+ TDG VS+ V + V+ ++K R F+ GIG G S SL+ +A+ G + F+ + A + L +A+ D L W P +S+ P IF L + + G + +K TL G + V+F+ + + + F +HRL AK+ I ++ S EE KKD++++SLQ +++ +T FVAI+++
Sbjct: 13 EKVPLKSISVTLSINDFVAAVAATLHYENEEKVPIEAMFVFPMDEDSAVYSFEALVDGKKIVAELQDKTKAHSKYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGTKVAVTLRYVQEL---PLESDGALRY--LLPAVLNPRYQLSEQSASSCLNVQKPIVPLEALPYTLSMVATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYREVHSPSVAVEKGMQD------KKRDSLMGAPCAMVSFYPDIPEVNASKVCG-EFVFLMDRSGSMQTPMRTEENSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEQFFPESVKYTQETIEEAVERVKRLDADLGGTEILTPLRNIYKTSSIPGHPLQLFVFTDGEVSDTYSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAEFITGKDRMQAKALGSLKLALQCA-LDDISLSWELPPGLSVNMLSPEQPTIFRGQRLIIYAQLTGPMPQAESRGAVCLKHTLQGKSLENKVAFSLQPKE-----NANFTIHRLAAKFLIQTKDLGSHEVSKEE--KKDVMNISLQSGVLSSFTAFVAINKE 594
BLAST of vault protein inter alpha trypsin-1 vs. UniProt/SwissProt
Match: sp|Q99KC8|VMA5A_MOUSE (von Willebrand factor A domain-containing protein 5A OS=Mus musculus OX=10090 GN=Vwa5a PE=1 SV=2) HSP 1 Score: 246.128 bits (627), Expect = 7.282e-68 Identity = 186/599 (31.05%), Postives = 299/599 (49.92%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGD------REVFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSI-VTAPKSIPPIFSDYFLTAFCMINGM-----KSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKIN--EMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
LK++SV +I +++ Y+N+ E F FP++ + VY FEALV GKKI+ ++ +A + YE A +GH A ++E++ DVF C +GN ++ + L++ EL P+ ++ R+ LLP IL PRY E + + + + + Y N A I IE V S I + +KTSA+V L + +D+++ I Y + PSV E+G L D S + AMV F P + C E V ++DRSGSM I+ AKE LL+ LKSLP+ C F IYGFGS ++K F +S Y+ ++ A+ K L AN GGTE++ PL ++Y + + F+ TDG VS+ V + V+ ++K R F+ GIG G S SL+ +A+ G +VF+ + + L A+ + L W P +S+ + +P+ + IF L + + G+ +G V +K L G + V+F+ + + D F +HRL AK I + Q S EE K+D++++SLQ +++ +T F+AI+++
Sbjct: 17 LKNISVTLSINEFVAAVVATLNYENEEKVPLEATFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKAHSEYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGAKVAVTLRYVQEL---PLETDGALRY--LLPAILNPRYQLSEQSANSCLNIQKPTVPLEDLPYTLNMTATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYNEVHSPSVAVEMGM---LDMKPD---SLMGAPSAMVSFYPDIPEVEASKAC-GEFVFLMDRSGSMDSPMSTENNSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEKFFPESVKYTQDTMEDAVKRVKALKANLGGTEILTPLCNIYKASSIPGHPLQLFVFTDGEVSDTFSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAVFITGKDRMQTKALGSLKFALQCA-VDNISLSWDLPPGLSVKMLSPEQL-TIFRGQRLIIYAQLTGLMPQVESTGAVCLKHILQGRSLENRVTFSLQPKAND-----NFTIHRLAAKSLIQTKDFGSQEASKEE--KEDVMNISLQSGVLSSFTAFIAINKE 594
BLAST of vault protein inter alpha trypsin-1 vs. UniProt/SwissProt
Match: sp|Q54CQ8|Y2740_DICDI (von Willebrand factor A domain-containing protein DDB_G0292740 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0292740 PE=4 SV=1) HSP 1 Score: 202.601 bits (514), Expect = 1.715e-52 Identity = 173/647 (26.74%), Postives = 310/647 (47.91%), Query Frame = 2
Query: 41 GLCPLKY---------DQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENV---SSVNHTLEIAFNNTNKTSAEVHLKSK--YDGTKDL-------DININYLAMKEPSVVYEVGSSSPLY----------SGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQ---CKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFND-SQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIA----MNSVPFTDAK-LEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMI--------NGMKSGDVIKCTLSGSAN-GEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAE-QIESGEETLKKDLIDLSLQVNIVTKYTTFVAI-DQDAPGEPLVTCI 1828
GL P+ Y + +F + S+D + + +C YKN+ E ++ P+ V F GK + G K+ +A+ Y+ A G A + EK+ + F ++GN P +E+ I + M SE+ + L Y R F +++Y ++ +N + I+++ +H+L+ + N KT + K ++ ++ D+N +++ S+ E ++P + K+ + S Y + F PKF+S +N + K E + ++D SGSM G+ ID A+ L I ++SL CKF IY FGS F+K F + S+ Y D S+ + Y N+ AN GGTEL++P++D+ + + +Y R F+LTDG VS++ ++ + V K +K+TR+FT GIG V + LV ++KA G +RN+ ++ VM+LL IA +++V F ++ L+ + +I+ +P I PIF++ + + I N G + T++ G+ +S+ E+ + + +H L A +I ++ E + +S +ET K ++I L + N+V+K+T+ V D D+P E + I
Sbjct: 58 GLAPIAYQYYNVSSFDNNQFKIVDFSIDSKLNDTCLTCVWTQTYKNESKTPVEAVYRIPLSPLSTVSAFSVQFNGKTLHGKIKDSTKAQEKYDDAIASGGQAFLAEKSKDDDNYFNFKLGNIPP-TESSITIHITM-------ISEIGSHLNSL------------HYLLHRYCFPQSSNYNFSLSLSVNLSNSIKSIFFDGDKSHSLQ--YENKEKTKCIIQYKKSLGFNTQPNILIVFELDDLNKPQSFIEKLSINKEDIKNNPHSDSDSDSDDEENKKENEKSSY---AIALNFFPKFES--INKEDIYQKGEFIFLIDCSGSMSGNPIDSARRALEIIIRSLNEQCKFNIYCFGSGFNKAFQEGSRKYDDDSLAVVNRYVSNISANLGGTELLQPIKDILSKEIDPEYPRQIFILTDGAVSDRSKLIEFVSKESKTTRIFTYGIGSSVDVELVVGLSKACKGYYTLIRNSSDMETEVMKLLSIAFEPTLSNVSFDWSQLLDLSNGKSTTIIQSPTQIRPIFNNERMMVYATIELDNDISNNIENHGQPVIVTMNADGPLGDRLSYHVELDFKN--YSQSNSIHTLAAFKRIQDLEEIERKSSKETEKLEIIKLGKKYNLVSKHTSLVVTSDSDSPTEDTMKVI 675
BLAST of vault protein inter alpha trypsin-1 vs. UniProt/SwissProt
Match: sp|Q54DV3|Y2016_DICDI (von Willebrand factor A domain-containing protein DDB_G0292016 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0292016 PE=4 SV=1) HSP 1 Score: 194.897 bits (494), Expect = 5.622e-50 Identity = 161/598 (26.92%), Postives = 281/598 (46.99%), Query Frame = 2
Query: 41 GLCPLK-YDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFN-NTNKTSAEVHLKSKYDG--TKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNN-QCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMI-NGMKSGDVIKC----------TLSGSA-NGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFV 1783
GL LK ++ F LK S++ I + S+ Y ND N E + P+ +V F+ GK I G KE E+A Y A G A + K+ F +GN P K+ + + SE+ D L L RY P YA + +N+ V+ + I+++ + + + N++K A++ KS++ K++ + I + + EP + E Y G S+ + F P F + + K+E + ++D SGSM G +I++A+ + I ++SL K IY FGS F+KVF+ S++Y+D ++ IA ++ + + AN GGTEL+ P+ D+ +S +Y R F+LTDG +S +D++ V K +TR+FT GIG V LV ++KA G ++ + VM+LL++A + ++ KL+W V ++ AP I P+F+ + + MI + + D+I TL+G G +SF + + ++H L A I ++ E ++ K +++L + +V+K+T+++
Sbjct: 47 GLYSLKNHNNVFVLKEFSIETEINDCSSTSIWTQSYSNDSNTPVEAKYQLPLHPTSVVSNFQIEYQGKVIQGKIKEKEKALEKYNDAIASGGQAFMATKSDD--GYFNLTLGNLPPKENVKVRVV---------ISSELGTHTDGQLHYCLH-RYMFPSYA-----------FNFNYNVVLKFSIPIKSIDCDGFDVNVNYKENSSKKEAKITSKSQHTSGVKKNIILIIQPVELNEPKSMIE-------YIGGGDDKSY----ATAINFYPSFKNVNPDEVYQKSEFIFLIDCSGSMSGQSINKARRAMEIIIRSLNEQHKVNIYCFGSSFNKVFDKSRVYNDETLEIAGSFVEKISANLGGTELLPPMVDILSSPNDPEYPRQVFILTDGEISERDKLIDYVAKEANTTRIFTYGIGASVDQELVIGLSKACKGYYEMIKETTNMEKQVMKLLNVAFEPM-LSNIKLDWSSCGLVDVIQAPSHIRPLFNQERMMIYSMIPSNQTNQDIINASIETSKPLIITLTGDGPKGNVLSFPITLDFKNDLSTNSNQIHTLAAFKHIQDLEESERKEKKDNKDKIVELGKKYGLVSKHTSYI 609
BLAST of vault protein inter alpha trypsin-1 vs. TrEMBL
Match: I1ZID1 (Vault protein inter alpha trypsin-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 524.242 bits (1349), Expect = 6.082e-171 Identity = 268/279 (96.06%), Postives = 273/279 (97.85%), Query Frame = 2
Query: 26 ITTMFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMV-KFLPKFDSS 859
++TMFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVF+CRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDR DLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMV K + K + S
Sbjct: 3 LSTMFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFRCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRLDLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVTKLVRKHNKS 281 HSP 2 Score: 411.764 bits (1057), Expect = 1.067e-127 Identity = 199/205 (97.07%), Postives = 203/205 (99.02%), Query Frame = 2
Query: 1223 VTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTCITDD 1837
VTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEE+LKKDLIDLSLQVNIVTKYTTFVAIDQ+APGEPLVT I ++
Sbjct: 271 VTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEESLKKDLIDLSLQVNIVTKYTTFVAIDQNAPGEPLVTNIEEE 475 HSP 3 Score: 107.457 bits (267), Expect = 4.852e-20 Identity = 45/99 (45.45%), Postives = 72/99 (72.73%), Query Frame = 3
Query: 2100 DIIMFLVDLQNINGSWNYDEKIFAYIGIDVNRIKEIQPDKISDIIWSTAVIYQHLMIKEQAREKEWRLFARKAKEWIEQNLNDSAIFNDILNKSAELFH 2396
D+I++LVD QNINGSWN++E I IG+++ + P +IS+ +W T IYQ+L++KE +REKEWRL A+KAK WIE+++ +S + + ++++L H
Sbjct: 588 DVIIYLVDKQNINGSWNFNESILLKIGVNITEFRNKMPGRISEEVWITVAIYQYLVLKESSREKEWRLVAKKAKNWIEKSIAESDLQDLAFREASDLLH 686
BLAST of vault protein inter alpha trypsin-1 vs. TrEMBL
Match: K1Q7V6 (von Willebrand factor A domain-containing protein 5A OS=Crassostrea gigas OX=29159 GN=CGI_10024419 PE=4 SV=1) HSP 1 Score: 329.717 bits (844), Expect = 2.305e-96 Identity = 205/589 (34.80%), Postives = 318/589 (53.99%), Query Frame = 2
Query: 86 LSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEY------NFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSK-YDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVI---KCTLSGSANGEPVSFTTEI-----RNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDAPG 1807
+ V +I L++S E Y +D +E+ E +F FP++ + VY FEA + GK I+ +E +AK Y+ A G+ A + + + D F+ ++GN P + A++ L++ E+ +S S+ + F +LP L PRY P + + + Y N AVI G V+ T + F+ + E+ SK D D I ++Y ++P VV E GS+ D F +DV MV F P F++ + NQ E VI++D SGSM GS +++AKE LL+ LKSLPV CKF I FGS+F +F +S Y ++S+ +A+ QKNL A+ GGTE+++PLE+++ + L +SR FLLTDG V N E+ +LVRK K+TR+FT G+GDG S L+ VAKAG GK+ FV+++ L + VM +L ++ S TD L W P + + P+++P IF +C+I+G + L+G A + + + + TDA D + +HRL AK + EM +I + +E+L ++ LS NI KYT FV +D+ + G
Sbjct: 36 IDVQVSINGLIASVKSELHYVSDKDENTETVFVFPLDSDAAVYEFEAEIDGKTIVAEVQEKSQAKETYQDAVASGYTAVYMSEADNAGDTFRLKLGNLPAKAAARLTLRYVQEVDVS---SDKIGTF--MLPRALNPRYVPNPSDASFRIHTIQSGVTYCPDFTMNLNAVIAG-----GTRMVDLTTKWEFDVLAEKMDEMISSSKQLDNGIDFSIVLHYKGFEQPGVVLETGSA-------DKNNPFLSTDVLMVNFSPNFEN--LENQVPCEFVIIIDCSGSMMGSRMEKAKETLLLILKSLPVNCKFTIIRFGSRFSSLFLESSKYDENSLKVAMQLQKNLQADMGGTEILKPLENVFKNRLSGCHSRQIFLLTDGAVYNVPELVQLVRKQ-KNTRVFTFGMGDGCSTELIRDVAKAGNGKATFVKDSDRLQSKVMSVLKASIQS-EITDVTLTWSLPTGCTAINVPENVPAIFDGEMFILYCIISGNVEESLFGKSSVVLTGHAGDKTLDYKMNFVLGSKKQTDA--DNLYPIHRLAAKASLTEM--EISNVKESL---MVSLSTTTNITCKYTAFVGVDKHSKG 596
BLAST of vault protein inter alpha trypsin-1 vs. TrEMBL
Match: A0A0R3TAC8 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS4016 PE=4 SV=1) HSP 1 Score: 311.997 bits (798), Expect = 6.730e-91 Identity = 204/614 (33.22%), Postives = 327/614 (53.26%), Query Frame = 2
Query: 65 QKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLL-PLILRPRYTPPEYAGDREVFQVTNH---YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPS-DYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCP---QHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIK----------CTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGE----------ETLKKDLIDLSLQVNIVTKYTTFVAIDQD----APGE 1810
+ +L V I N + TC F+Y+N +E E F FP+E VY+ EA++G K+++ C+E EA+ Y A EKGH A +++++ M D FK ++GN P + +I K+ + L L V + + +RF L P++ ++ P G R V + NF A I G I +V+S +HTL++ + N K+ A+V L D ++ I AM +P ++ +SP G +G F FLP S ++ K EI+ V+DRSGSMRGS I ++KE LL+FLKSLP C+FQI FGS+F +F Y++ ++ AL++Q L+AN GGTEL L+ +Y++ + + R +LTDG + NQD+V LVRK+ + R+F +G+G+ VS SL+ +A+AG G + F+R++ L + +L + + D L+W + V I+T P +PP+FS +FLTAF G+ + V TLS N E + T+++ + E +HRL AK ++ E+ + S E E +++ ++D+S+ N++ ++TTFV +D D APG+
Sbjct: 21 ESVALDKYDVSALIINNNADVTCNFLYENTSSELIEAEFIFPLESTAAVYHLEAVIGKKRLVAKCRERVEAEATYNEAVEKGHTAFMMQEDFHMGDTFKMKLGNIPAGDKIEITFKYVVPLYLREVDTSL-ERFKSLKEPVVCV--FSMPGKIGARYGANVPASKLAAKMNFVAEIYGAGGILSVTSPHHTLQVNYLNEEKSRAKVSLSDGVVVENDFEMEI---AMDKPHIL-----ASPCEIGSVEKGGFLGMHCIAASFLPNIAQSRASDGDKCEIIFVLDRSGSMRGSRIQKSKEALLLFLKSLPKKCRFQIVSFGSRFSSLFPQPVDYTEENVKQALDHQSQLEANMGGTELYPALKSIYDTPITGVGWYRQIIVLTDGEIFNQDDVIGLVRKNQVNARVFAIGLGNEVSTSLIWGIARAGRGTASFIRDSDNLRTGALSVLKATLQPM-LKDVSLKWDVKVDGKAVEILTVPSQLPPLFSGHFLTAF----GLTAASVKSNSGSPEVEGTLTLSYKLNEEVHTQTSKVESLGVEY-ENLGLHRLAAKAQLLELVDMYSSLEGRGEEGKKEAEEVRQQIVDISVNANVIARFTTFVGVDPDKIDSAPGK 617
BLAST of vault protein inter alpha trypsin-1 vs. TrEMBL
Match: A0A068WQX3 (von Willebrand factor A domain containing protein OS=Echinococcus granulosus OX=6210 GN=EgrG_001168700 PE=4 SV=1) HSP 1 Score: 315.079 bits (806), Expect = 4.832e-90 Identity = 197/602 (32.72%), Postives = 320/602 (53.16%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLL---------LPLILRPRYTP-PEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLP-SDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCP---QHVSIVTAPKSIPPIFSDYFLTAFCMINGMKS-GDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEE-FRVHRLLAKYKINEMAEQI------------ESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
L+ V I N + +CEF YKN +E E F+FP+E VY+ EA++G K ++ C+E EA+ Y A E GH A +++++ +M D F+ ++GN P K+ ++ + L + V + ++RF L +PL++ RY P P G ++ + +F A I T + +V+S + +++F + K A++ + D + D ++ LA++ P + +P G ++G F FLP S ++ K EI+ V+DRSGSM GS I KE LL+FLKSLP C+FQI GFGS F+ +F Y+ ++ AL YQK L AN GGTE++ L+ +Y++ + + + R LTDG +SNQDEV LV ++ +S RLF +G+GD VS SL+ VA+AG G +VF+R+ L A+ M +L A+ + TD +L+W + I+T P +PP+FS F+TAF + S I+ TL S + E V++E +HRL AK ++ E+ ++ ES + +++ ++D+S N+++ +T+FV +D D
Sbjct: 17 LEKFDVHAVIVNNNADVSCEFAYKNSTSEIIETEFAFPLESTAAVYHLEAIIGKKHLVAHCRERIEAEETYSEAVESGHTAFMMQEDYTMGDTFRMKLGNIPAGETIKLTFRYVVPLYVREV-DKTIERFSGLQEPYVLIFSMPLLIGERYDPNPGAHGCTAAPHLS--AKMSFVADICATGGVLSVTSAHQKFQVSFVDEAKEHAKITVPGNLDLSHDFELE---LALQNPHAL-----CAPCELGCASKGGFLGMHCITAAFLPNISQSPASDGDKREIIFVIDRSGSMSGSKIQNTKESLLLFLKSLPKKCRFQIVGFGSSFNPLFPQPVDYNKENVEQALGYQKTLSANMGGTEVLSVLKFVYDTPVTGAGWYRCIIFLTDGEISNQDEVIGLVTRNQQSARLFAIGLGDEVSTSLIWGVARAGRGTAVFIRSGDNLRAATMSVLGSALQPM-LTDVELKWDVKVDGKAPEILTVPTRLPPLFSGVFMTAFGLFQADDSKSPRIEGTLKLSYKLNDTVHSQETAVQILPVEQENLGLHRLAAKAQLLELVDKHSALHANDGDKVDESAKSEIRQQIVDISTNTNVISPFTSFVGVDPD 606
BLAST of vault protein inter alpha trypsin-1 vs. TrEMBL
Match: W6ULK4 (von Willebrand factor A domain-containing protein 5A OS=Echinococcus granulosus OX=6210 GN=EGR_06108 PE=4 SV=1) HSP 1 Score: 312.768 bits (800), Expect = 1.313e-89 Identity = 196/602 (32.56%), Postives = 319/602 (52.99%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLL---------LPLILRPRYTP-PEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLP-SDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCP---QHVSIVTAPKSIPPIFSDYFLTAFCMINGMKS-GDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEE-FRVHRLLAKYKINEMAEQI------------ESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
L+ V I N + +CEF YKN +E E F+FP+E VY+ EA++G K ++ C+E EA+ Y A E GH A +++++ +M D F+ ++GN P K+ ++ + L + V + ++RF L +PL++ RY P P G ++ + +F A I T + +V+S + +++F + K A++ + D + D ++ LA++ P + +P G ++G F FLP S ++ K EI+ V+DRSGSM GS I KE LL+FLKSLP C+FQI GFGS F+ +F Y+ ++ AL YQK L AN GGTE++ L+ +Y++ + + + R LTDG +SNQDEV LV ++ +S RLF +G+GD VS SL+ VA+AG G +VF+R+ L A+ M +L A+ + TD +L+W + I+ P +PP+FS F+TAF + S I+ TL S + E V++E +HRL AK ++ E+ ++ ES + +++ ++D+S N+++ +T+FV +D D
Sbjct: 17 LEKFDVHAVIVNNNADVSCEFAYKNSTSEIIETEFAFPLESTAAVYHLEAIIGKKHLVAHCRERIEAEETYSEAVESGHTAFMMQEDYTMGDTFRMKLGNIPAGETIKLTFRYVVPLYVREV-DKTIERFSGLQEPYVLIFSMPLLIGERYDPNPGAHGCTAAPHLSA--KMSFVADICATGGVLSVTSAHQKFQVSFVDEAKEHAKITVPGNLDLSHDFELE---LALQNPHAL-----CAPCELGCASKGGFLGMHCITAAFLPNISQSPASDGDKREIIFVIDRSGSMSGSKIQNTKESLLLFLKSLPKKCRFQIVGFGSSFNPLFPQPVDYNKENVEQALGYQKTLSANMGGTEVLSVLKFVYDTPVTGAGWYRCIIFLTDGEISNQDEVIGLVTRNQQSARLFAIGLGDEVSTSLIWGVARAGRGTAVFIRSGDNLRAATMSVLGSALQPM-LTDVELKWDVKVDGKAPEILIVPTRLPPLFSGVFMTAFGLFQADDSKSPRIEGTLKLSYKLNDTVHSQETAVQILPVEQENLGLHRLAAKAQLLELVDKHSALHANDGDKVDESAKSEIRQQIVDISTNTNVISPFTSFVGVDPD 606
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000016124.2 (pep primary_assembly:Astyanax_mexicanus-2.0:8:24927342:24950812:1 gene:ENSAMXG00000015665.2 transcript:ENSAMXT00000016124.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 242.662 bits (618), Expect = 4.306e-68 Identity = 167/605 (27.60%), Postives = 293/605 (48.43%), Query Frame = 2
Query: 41 GLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNH-----YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKT-EIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKIN--EMAEQIESGE-ETLKKDLIDLSLQVNIVTKYTTFVAIDQDA 1801
GL +K ++ LKS+ V+ ++ +++ + Y N+ E LF FP+ + +F A +G ++ + +E E+AK+ Y+ A G A ++E++ DVFK +G+ P A + + EL V+++ RF LP +L PRY+PP ++ Q+T Y +F A ++ I V S LE NT++T+A+V L + + +D+++ + Y +P+ + E G + G+ V M+ P+F ++M++ E V V+DRSGSM + I+ A++ L++ LKSLP+ C F IY FGS + +F S Y++ ++ A+ K + ++ GGTE++ PL ++Y+ ++ R F+ TDG V N +V +LVR + R F+ GIG+G S +L+ +A+ G G + F+ + + VM+ L A+ D W P +S + P + F +I G+V G+ + E+ NT +HRL A+ I E EQ E E E LK +++LS++ + +T F+A+ + +
Sbjct: 6 GLLTVK-NEPVPLKSIEVELQVQGHVATVSSTLQYTNEEQSPLEALFVFPLPAESALCHFSAKIGDQETVAKVQEKEKAKDEYDDAIASGQQAFLLEESDESEDVFKLSVGSLPPGQSAAVTFIYVTELS---VQADHSLRF--CLPAVLNPRYSPP----GTKLPQITERQMLIPYSLSFTATVSSPNPIAKVES-KCALEPLVFNTDRTNAKVSLSAGHKFDRDVELYLYYENAHQPTAIVEAGVPT------AKPGTLMGDPVVMLSLYPEFPEAIMSSMSTCGEFVFVMDRSGSMGCAMHNGPGAKMRIESARDTLVLLLKSLPMGCYFNIYSFGSHYKSLFPKSVEYTEETMDQAVKRVKEMQSDMGGTEILEPLRNIYSQQCIPNHPRQVFIFTDGEVGNTKDVLQLVRNNADHHRCFSFGIGEGASTALIKGMAQEGRGHNQFITGSDRMQPKVMQSLRYALQPA-VIDITEVWSVPAGMSTT----HLSPPLNVLFHGQRALIYAQLKGEVRTPDSQGTITVKYQLAGQEVTNT-------LSIHRLAARSLIRSLERQEQTEGAEKEALKARVVELSVEAGVSCSHTAFIAVHKGS 581
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000043227.1 (pep primary_assembly:Astyanax_mexicanus-2.0:8:24927342:24946352:1 gene:ENSAMXG00000015665.2 transcript:ENSAMXT00000043227.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 243.047 bits (619), Expect = 7.197e-68 Identity = 164/605 (27.11%), Postives = 295/605 (48.76%), Query Frame = 2
Query: 41 GLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNH----YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKT-EIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDV-IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKIN--EMAEQIESGE-ETLKKDLIDLSLQVNIVTKYTTFVAIDQDA 1801
GL +K ++ LKS+ V+ ++ +++ + Y N+ E LF FP+ + +F A +G ++ + +E E+AK+ Y+ A G A ++E++ DVFK +G+ P A + + EL V+++ RF LP +L PRY+PP ++ Q+T Y +F A ++ I V S LE NT++T+A+V L + + +D+++ + Y +P+ + E G + G+ V M+ P+F ++M++ E V V+DRSGSM + I+ A++ L++ LKSLP+ C F IY FGS + +F S Y++ ++ A+ K + ++ GGTE++ PL ++Y+ ++ R F+ TDG V N +V +LVR + R F+ GIG+G S +L+ +A+ G G + F+ + + VM+ L A+ D W P +S + +F + + G G + +K L+G ++++ + +HRL A+ I E EQ E E E LK +++LS++ + +T F+A+ + +
Sbjct: 6 GLLTVK-NEPVPLKSIEVELQVQGHVATVSSTLQYTNEEQSPLEALFVFPLPAESALCHFSAKIGDQETVAKVQEKEKAKDEYDDAIASGQQAFLLEESDESEDVFKLSVGSLPPGQSAAVTFIYVTELS---VQADHSLRF--CLPAVLNPRYSPP----GTKLPQITERQIIPYSLSFTATVSSPNPIAKVES-KCALEPLVFNTDRTNAKVSLSAGHKFDRDVELYLYYENAHQPTAIVEAGVPT------AKPGTLMGDPVVMLSLYPEFPEAIMSSMSTCGEFVFVMDRSGSMGCAMHNGPGAKMRIESARDTLVLLLKSLPMGCYFNIYSFGSHYKSLFPKSVEYTEETMDQAVKRVKEMQSDMGGTEILEPLRNIYSQQCIPNHPRQVFIFTDGEVGNTKDVLQLVRNNADHHRCFSFGIGEGASTALIKGMAQEGRGHNQFITGSDRMQPKVMQSLRYALQPA-VIDITEVWSVPAGMSTTHLSPPLNVLFHGQRALIYAQLKGEVRGTITVKYQLAGQEVTNTLNYSLKPAENSG-----LSIHRLAARSLIRSLERQEQTEGAEKEALKARVVELSVEAGVSCSHTAFIAVHKGS 587
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Cavefish
Match: si:ch73-265h17.1 (von Willebrand factor A domain-containing protein 5A-like [Source:NCBI gene;Acc:103024697]) HSP 1 Score: 240.35 bits (612), Expect = 1.139e-66 Identity = 175/596 (29.36%), Postives = 293/596 (49.16%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEY-AGDREVFQVTNH--YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNN-QCKTEIVIVVDRSGSMR-----GSN----IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM-KSGD-----VIKCTLSGSANGEPVSFTTE-IRNTDAFVDEEFRVHRLLAKYKINEMAEQIES-GEETLKKDLIDLSLQVNIVTKYTTFVAIDQDA 1801
LKS+ V+ ++ +++ + YKN+ E LF FPI + + +F A +G ++I+ +E E+A+ Y+ A G A ++E++ DVFK +G+ P A + + EL V+++ RF LP +L PRY PP +G V+ Y +F A ++ + V S + F N +TSA+V L + KD+++ + Y +P+ + E + QG+ V M+ P F ++M++ + E V V+DRSGSM GS I+ A++ LL+ LKSLP+ C F IYGFGS ++ F S Y+ ++ A+N K++ A+ GGTE++ PL+ +Y ++ R F+ TDG V N +V LV+K KS R FT GIG+G S +L+ +A+ G G + F+ + + VM+ L A++ D W P +S + IF + + G KS D +K L+G +SF+ + NT +HRL A+ I + Q ++ G E LK +++LS++ + +T F+A+ + +
Sbjct: 16 LKSIEVELQVQGHVATVSSTLQYKNEEQSPLEALFVFPIPADAALCHFSAKIGDQEIVSKLQEKEQARYEYDDAIASGQQAFLLEESDESEDVFKLSVGSLPPGQSAAVTFIYVTELS---VQADHSLRF--CLPAVLNPRYLPPGSDSGIVSEITVSESIPYSLSFTATVSSPNPVAKVESKCALDPLVFLNAERTSAKVSLSVGHKFDKDVELYLYYENAHQPTAIVEAAVPT------AKQGTLMGDPVVMLSLYPDFPEAVMSSMSSRGEFVFVMDRSGSMACPMHFGSGAQERIESARDTLLLLLKSLPLGCYFNIYGFGSSYESYFPTSVEYTQKTMDEAVNRVKDMHADLGGTEILEPLKHIYKQKCIPNHPRQVFIFTDGEVGNTKQVISLVKKEAKSHRCFTFGIGEGASTALITGMAQNGRGHAQFITGSDRMQPKVMQSLHYALHPA-VDDITDVWTVPAGMSTTRLSPPLSVIFQGQRALIYAQLKGQCKSSDSEGTVTVKYRLAGQEVSNTLSFSLKPAENTG------LSIHRLAARSLIRSLERQEQTEGPEALKARVVELSVEAGVSCSHTAFIAVHKSS 593
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Cavefish
Match: si:ch73-265h17.1 (von Willebrand factor A domain-containing protein 5A-like [Source:NCBI gene;Acc:103024697]) HSP 1 Score: 239.965 bits (611), Expect = 2.369e-66 Identity = 175/596 (29.36%), Postives = 293/596 (49.16%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEY-AGDREVFQVTNH--YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNN-QCKTEIVIVVDRSGSMR-----GSN----IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM-KSGD-----VIKCTLSGSANGEPVSFTTE-IRNTDAFVDEEFRVHRLLAKYKINEMAEQIES-GEETLKKDLIDLSLQVNIVTKYTTFVAIDQDA 1801
LKS+ V+ ++ +++ + YKN+ E LF FPI + + +F A +G ++I+ +E E+A+ Y+ A G A ++E++ DVFK +G+ P A + + EL V+++ RF LP +L PRY PP +G V+ Y +F A ++ + V S + F N +TSA+V L + KD+++ + Y +P+ + E + QG+ V M+ P F ++M++ + E V V+DRSGSM GS I+ A++ LL+ LKSLP+ C F IYGFGS ++ F S Y+ ++ A+N K++ A+ GGTE++ PL+ +Y ++ R F+ TDG V N +V LV+K KS R FT GIG+G S +L+ +A+ G G + F+ + + VM+ L A++ D W P +S + IF + + G KS D +K L+G +SF+ + NT +HRL A+ I + Q ++ G E LK +++LS++ + +T F+A+ + +
Sbjct: 16 LKSIEVELQVQGHVATVSSTLQYKNEEQSPLEALFVFPIPADAALCHFSAKIGDQEIVSKLQEKEQARYEYDDAIASGQQAFLLEESDESEDVFKLSVGSLPPGQSAAVTFIYVTELS---VQADHSLRF--CLPAVLNPRYLPPGSDSGIVSEITVSESIPYSLSFTATVSSPNPVAKVESKCALDPLVFLNAERTSAKVSLSVGHKFDKDVELYLYYENAHQPTAIVEAAVPT------AKQGTLMGDPVVMLSLYPDFPEAVMSSMSSRGEFVFVMDRSGSMACPMHFGSGAQERIESARDTLLLLLKSLPLGCYFNIYGFGSSYESYFPTSVEYTQKTMDEAVNRVKDMHADLGGTEILEPLKHIYKQKCIPNHPRQVFIFTDGEVGNTKQVISLVKKEAKSHRCFTFGIGEGASTALITGMAQNGRGHAQFITGSDRMQPKVMQSLHYALHPA-VDDITDVWTVPAGMSTTRLSPPLSVIFQGQRALIYAQLKGQCKSSDSEGTVTVKYRLAGQEVSNTLSFSLKPAENTG------LSIHRLAARSLIRSLERQEQTEGPEALKARVVELSVEAGVSCSHTAFIAVHKSS 593
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000052541.1 (pep primary_assembly:Astyanax_mexicanus-2.0:8:24927282:24943774:1 gene:ENSAMXG00000015665.2 transcript:ENSAMXT00000052541.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 236.113 bits (601), Expect = 6.163e-66 Identity = 163/610 (26.72%), Postives = 293/610 (48.03%), Query Frame = 2
Query: 41 GLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNH----YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKT-EIVIVVDRSGSMRGS---------NIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMING------MKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKIN--EMAEQIESGE-ETLKKDLIDLSLQVNIVTKYTTFVAIDQDA 1801
GL +K ++ LKS+ V+ ++ +++ + Y N+ E LF FP+ + +F A +G ++ + +E E+AK+ Y+ A G A ++E++ DVFK +G+ P A + + EL V+++ RF LP +L PRY+PP V ++T Y +F A ++ I V S LE NT++T+A+V L + + +D+++ + Y +P+ + E G + G+ V M+ P+F ++M++ E V V+DRSGSM + I+ A++ L++ LKSLP+ C F IY FGS + +F S Y++ ++ A+ K + ++ GGTE++ PL ++Y+ ++ R F+ TDG V N +V +LVR + R F+ GIG+G S +L+ +A+ G G + F+ + + VM+ L A+ D W P +S + +F + + G + +K L+G ++++ + +HRL A+ I E EQ E E E LK +++LS++ + +T F+A+ + +
Sbjct: 5 GLLTVK-NEPVPLKSIEVELQVQGHVATVSSTLQYTNEEQSPLEALFVFPLPAESALCHFSAKIGDQETVAKVQEKEKAKDEYDDAIASGQQAFLLEESDESEDVFKLSVGSLPPGQSAAVTFIYVTELS---VQADHSLRF--CLPAVLNPRYSPPGTQAGV-VSEITTSASIPYSLSFTATVSSPNPIAKVES-KCALEPLVFNTDRTNAKVSLSAGHKFDRDVELYLYYENAHQPTAIVEAGVPT------AKPGTLMGDPVVMLSLYPEFPEAIMSSMSTCGEFVFVMDRSGSMGCAMHNGPGAKMRIESARDTLVLLLKSLPMGCYFNIYSFGSHYKSLFPKSVEYTEETMDQAVKRVKEMQSDMGGTEILEPLRNIYSQQCIPNHPRQVFIFTDGEVGNTKDVLQLVRNNADHHRCFSFGIGEGASTALIKGMAQEGRGHNQFITGSDRMQPKVMQSLRYALQPA-VIDITEVWSVPAGMSTTHLSPPLNVLFHGQRALIYAQLKGENQTPDSQGTITVKYQLAGQEVTNTLNYSLKPAENSG-----LSIHRLAARSLIRSLERQEQTEGAEKEALKARVVELSVEAGVSCSHTAFIAVHKGS 594
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000973.1 (pep scaffold:Pmarinus_7.0:GL479898:11183:30237:-1 gene:ENSPMAG00000000879.1 transcript:ENSPMAT00000000973.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 220.705 bits (561), Expect = 5.553e-63 Identity = 156/509 (30.65%), Postives = 245/509 (48.13%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGK-KIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEY-----NFKAVINGTKVIEN------VSSVNHTL-EIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLP-KFDSSLMNNQCKTEIVIVVDRSGSMR---------GSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMING 1534
L+S++V ++ ++ +Y N E + FP+ N V+ F A VG + + + + A Y+ A KGHMAA + + DVF C +GN EA++ L+F EL + P + RF LP +L PRY+P + G + +EY N ++ T EN VSS + L +AF KTSA+V L+ + D+++ I+Y +P + E G A+ SF VAM+ F P + + + E + ++D SGSMR + +KE L++ +KSLP+ C F IY FG+++ +F +S Y+ +I AL + K DA+ GGT ++ PL D+Y ++ R FLLTD V N + V + V+ H+ R F GIG GVS L+ +VA+ G G S FV ++ +L A V+ +L AM + + +LEW P V++ P IF + + G
Sbjct: 3 LRSVAVKALVQGFVADVVASMIYHNKEAFPVEPSYFFPLNDNSAVHAFRARVGDRARYVVTTRLTTPAVEEYDDAIAKGHMAAQLSQQCG--DVFHCVLGNLGAGEEAEVTLEFVSELDVGP---DGAVRF--CLPTVLNPRYSP-QGTGFPLCSRSMIPWEYLAPSQNVPYTLSFTLTAENPGGILDVSSPSDLLGPVAFTEPGKTSAQVSLEGDFRFDHDIEVLISYEQKHQPFALVEPGLPV-------AEVSFLADTVAMLNFFPGDMEQTAVPTSEHGEFIFIIDCSGSMREPLSTTAPYDARWRTSKETLILLIKSLPMGCLFNIYRFGTRYISLFGESTPYNQQTIEAALAHVKRADADMGGTNILEPLADIYRQPCKPEHPRKLFLLTDEMVMNTEGVIQKVKNHSMDHRCFAFGIGQGVSTQLIKEVARVGNGLSEFVTSSDQLQAKVLRMLKCAMQPL-LGNPQLEWSLPPGVTVTVVPTLPRSIFMGQKMIVYAQFTG 495
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001499.1 (pep scaffold:Pmarinus_7.0:GL486103:7907:24271:-1 gene:ENSPMAG00000001355.1 transcript:ENSPMAT00000001499.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 145.591 bits (366), Expect = 3.795e-38 Identity = 103/325 (31.69%), Postives = 157/325 (48.31%), Query Frame = 2
Query: 554 YEYNFKAVINGTKVIENVSSVNHTLEIA-FNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLP-KFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAK--ECLLIFLKSLPVYCK-------FQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIF 1495
Y +F I++VSS + L A F +++ SA+V L+ + +D+++ I Y +P + E G + A+ SF VAM+ F P + + + E + ++D SGSM + I AK LLI +++L + K F IY FGS+F ++ +S Y ++ AL + ++DAN GGT +M PL D+Y + R FLLTDG V N V V+ H+ R F GIG GVS L+ +VA G G S FV ++ L V+ +L AM + +LEW P + P+ IF
Sbjct: 7 YTLSFTLTAENPGGIDDVSSPSGLLGPATFAESDRASAQVSLEGNFKFDQDIEVLIYYKQKHQPFALIEPGLPA------TAEVSFLADTVAMLNFFPGEMEEMEVPTAEHGEFIFIIDCSGSMNNNPIMSAKVPRTLLINMETLILLLKSLSLGCLFNIYSFGSRFKSLYTESMPYDQQTMDTALKHVCSMDANMGGTNIMGPLVDIYKQPCKPQHPRKLFLLTDGMVDNTQGVIHTVKHHSMDHRCFAFGIGQGVSTELIKEVAHVGKGLSEFVTSSDRLQGKVLRMLKCAMQPS-LNNPQLEWTLPPGIVATVVPRLPESIF 324
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009885.1 (pep scaffold:Pmarinus_7.0:GL476547:520883:546470:1 gene:ENSPMAG00000008938.1 transcript:ENSPMAT00000009885.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 137.117 bits (344), Expect = 3.913e-33 Identity = 148/605 (24.46%), Postives = 250/605 (41.32%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDR-----EVFQVTNH---YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGT-KDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLA-------FLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVF--VRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSI------VTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEET--------LKKDLIDLSLQVNIVTKYTTFVAIDQ 1795
LK++ V NI + + Y ND E E ++FP++ V FEA + GK I+G KE E A Y A +GH A ++++ + DVF +GN P I + + EL RF L P L P + GD E V H + + + I NV+S H + + A V L S D + + + + EP + E Q S ++ F P+F S +IV+ +D S SM + AK L L+ LP +F + FG+ + ++F + S +I A+++ K L A+ G TEL RPL + SR A LLTDG ++ T+ R++ + R+ G+G+ + ++ +A+ G F +N + ++ L++ A V D +EW ++ + AP+ I +F L + ++ + TL N + F+T + ++ + +HRL A I + + +ET +K +I+LS + +I+T YT+FVA+++
Sbjct: 357 LKAVHVRANILDFTAQVVVMQEYDNDSTEPIEAKYTFPLDEMAAVCSFEAFINGKHIVGQVKEKETAHQQYRNAVSQGHGAYLMDQESP--DVFVVSVGNLPPACRVLIKVTYVCEL----AAEGAAVRFRL--PGNLAP-WQQRLATGDVTQETVETLAVAKHSGRVRLSVQVSVEMPYEIINVTSPTHAIRV---KRTACKAVVELASSDDSLGSEFQLLVFPAQIHEPRMWVE-------------QNPETDSQACILTFYPEFAPSPSEG---VDIVLCLDCSASMTTQPLTDAKRLALFALRHLPPGSRFNVLKFGTHYKELFPVFRESSPSNIATAVSFIKRLHADAGNTELWRPLRSVALLAGGVGGSRDAAAPPVSVLLLTDGVAQSEARATREARENVRLLRVLACGVGETPNRYFLNALARNSGGACEFFTAKNRSTWTDKMLALMEKATQPV-CRDVTVEWQRFDRGALGGDRVEMQAPRMIRSVFCGTRLVVYGIVP-----HCTQATLHAIINNQ--EFSTMVSTSNLQITRGKMLHRLTAHAIIQDYEDGNLHPDETQHEVIIAEMKSRIIELSKEYSIITPYTSFVAVEE 925
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009886.1 (pep scaffold:Pmarinus_7.0:GL476547:520883:541043:1 gene:ENSPMAG00000008938.1 transcript:ENSPMAT00000009886.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 111.694 bits (278), Expect = 2.359e-25 Identity = 110/418 (26.32%), Postives = 170/418 (40.67%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDR-----EVFQVTNH---YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGT-KDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLA-------FLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIG 1282
LK++ V NI + + Y ND E E ++FP++ V FEA + GK I+G KE E A Y A +GH A ++++ + DVF +GN P I + + EL RF L P L P + GD E V H + + + I NV+S H + + A V L S D + + + + EP + E Q S ++ F P+F S +IV+ +D S SM + AK L L+ LP +F + FG+ + ++F + S +I A+++ K L A+ G TEL RPL + SR A LLTDG ++ T+ R++ + R+ G+G
Sbjct: 373 LKAVHVRANILDFTAQVVVMQEYDNDSTEPIEAKYTFPLDEMAAVCSFEAFINGKHIVGQVKEKETAHQQYRNAVSQGHGAYLMDQESP--DVFVVSVGNLPPACRVLIKVTYVCEL----AAEGAAVRFRL--PGNLAP-WQQRLATGDVTQETVETLAVAKHSGRVRLSVQVSVEMPYEIINVTSPTHAIRV---KRTACKAVVELASSDDSLGSEFQLLVFPAQIHEPRMWVE-------------QNPETDSQACILTFYPEFAPSPSEG---VDIVLCLDCSASMTTQPLTDAKRLALFALRHLPPGSRFNVLKFGTHYKELFPVFRESSPSNIATAVSFIKRLHADAGNTELWRPLRSVALLAGGVGGSRDAAAPPVSVLLLTDGVAQSEARATREARENVRLLRVLACGVG 762
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Nematostella
Match: EDO46745 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNW3]) HSP 1 Score: 292.738 bits (748), Expect = 7.634e-86 Identity = 190/607 (31.30%), Postives = 290/607 (47.78%), Query Frame = 2
Query: 41 GLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTP----PEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININ------YLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGD--------VIKCTLSGSANGEPVSFTTEIRNTDAFV-----DEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAID 1792
GL K +K L+S+ V+ I + YKN+G+ E ++ FP++ V F+A + G+ I+ KE EEA+ Y+ A GH A ++E++ D+F+ +GN P N A + LKF EL++ V +LP +L PRYTP P + + V Y + F+ + I +SS +H L + ++ A V L + +D++I I A+ EP + + G F VAMV F+P F + + C E + VVDRSGSM GS I A L +FLKSLP C F I GFGS + +F+ S+ Y+D ++ A N+ +L A+ GGTE++ PL +Y+ L R FLLTDG V N +V LV ++ + R+F+ GIGDG S L+ VA+AG G + FVR +L V++ L A+ TD L W P + +PP+F L A+ + + + +K TL + I NT FV + +HRL AK I+ + K+D+I LS ++ +K+T+F+A+D
Sbjct: 4 GLICKKTKEKIPLQSIKVNAEITGYTAQVAAVLGYKNEGSNPIEAVYIFPLDEQAAVCGFQATIDGRTIVAEIKEKEEARGDYDDAISSGHSAFLLEESDESSDIFQMNVGNLPPNESATLQLKFVTELEVDEENGTV----QFVLPTVLNPRYTPVDQQPSISTEIPASSVAKPYSFEFQMNVKSGSAITEISSTSHKLCFQPDPSDNCHASVTLAESHTFRRDVEIQIKSEDPFVAHALVEPGLPRPSDAPEDKTRGLAISTEFLQKPVAMVNFVPAFKADDLT--C-GEFIFVVDRSGSMSGSRIKDAARTLQLFLKSLPDGCYFNIVGFGSSYKTLFSKSKTYNDETLKTATNHAAHLAADLGGTEILEPLRWVYSQSLIEGAPRQLFLLTDGEVGNTAQVISLVAENASTARVFSFGIGDGASTELIKGVARAGHGSAEFVRGQDKLQVKVIKTLKRALQPA-LTDVALSWALPDGWKLQEVQSKLPPVFKGERLIAYGVFKNLNNDSNAKGIGHATVKATLHEGREAK------HIENTVKFVLLPSQENSLVLHRLAAKRFISSSQSALH------KQDIIQLSKTASVASKFTSFIAVD 590 HSP 2 Score: 50.0618 bits (118), Expect = 4.425e-6 Identity = 32/103 (31.07%), Postives = 51/103 (49.51%), Query Frame = 3
Query: 2100 DIIMFLVDLQNINGSWNYDEKIFAYIGID----VNRIKEIQPDKISDIIWSTAVIYQHLMIKEQAREKEWRLFARKAKEWIEQNLNDSAIFNDILNKSAELFH 2396
D +M LVDLQ GSW + + A + + VN + PD SDI W+T ++ L K R+ EW + A K+K W++ +L + ++ + FH
Sbjct: 696 DKLMTLVDLQKACGSWELTDALAACLNVSKDVLVNAKPQSTPDLGSDI-WATVLVLVWLSGKFFNRKDEWEMIANKSKRWLKSSLPSGVDYGKLM---GDAFH 794
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Nematostella
Match: EDO45203 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTF3]) HSP 1 Score: 272.707 bits (696), Expect = 5.916e-79 Identity = 185/612 (30.23%), Postives = 305/612 (49.84%), Query Frame = 2
Query: 38 FGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDR---EVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKE--PSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKT-EIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIP-PIFSDYFLTAFCMINGMKSGD----VIKCTLSGSANG---------EPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINE----MAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDA 1801
FGL +Q L+ + + + + Y N E ++ P++ V F+A + G+ I+ +E +EA++ Y+ A GH A ++E++ D+F+ +GN P S AK+ L F EL + E R LLP +L PRYTP G+ + +V + YE++F+ ++ I+ ++S + L + ++ +K A V L + D+D+ + L P +E G +G + F + + F+P F +T E + V+DRSGSM G I A+E L +FLKSLP +C F + GFGS ++K+F+ S YSD S+ A N+ KNL+AN GGTE++ PL+ +++ + R FL+TDG V N +V LV+K++ R FT GIG G S +L+ VA+AG G + F+ ++ ++ A V++ L A+ D K+ W P T PK++P +FS + + +++ G K TL + V+F E++ +D +HR+ AK I E M E S + LK +I++S N+V+K T+FVA+D ++
Sbjct: 4 FGLIDSSRNQ-VPLQRIEIRAKVHGYTAEVIATMTYNNKMKNPIEAVYILPLDEEAAVCGFKATIDGRTIVAEVQEKQEARDTYDDAISSGHSAFLLEESDESSDIFQINVGNLPAESTAKVELTFVCELTV-----EKEGRVCFLLPTVLNPRYTP--QGGNSITASLPRVDSAYEFDFELLVQSASEIQEITSPHSKLNVVISSEDKCQATVRLAEPFKF--DVDVKVMILNRDPFLPQATFENG-----VTGSNITQDFLEKPLVTLNFMPDFGK---QEALETGEFIFVIDRSGSMSGDRIKNARETLFLFLKSLPEHCHFNVVGFGSSYEKLFSSSTKYSDSSVNKACNHAKNLEANLGGTEILEPLKYVFSQPVIKGSPRQVFLMTDGEVGNTQQVITLVKKNSTHARCFTFGIGQGASTALIKGVARAGQGTAEFITSSHQMQAKVVKTLRNALQP-SMEDIKVTWDLPHGWDSQTIPKNLPQALFSGNRIIVYGLLSKQGGGRDEELQGKATLQATTRDNTSNMRTITHEVAFKLELKESDGCS----MMHRVAAKRFIQEQQDAMGEDASSWSDDLKAKVINISKAANVVSKVTSFVAVDSES 592
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Nematostella
Match: EDO32379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SV91]) HSP 1 Score: 192.971 bits (489), Expect = 4.834e-52 Identity = 157/613 (25.61%), Postives = 276/613 (45.02%), Query Frame = 2
Query: 38 FGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEA--KNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGD----REVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSK-YDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMY-NSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMI----NGMKSGDVI---KCTLSGSAN--------GEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQ----IESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQ 1795
+GL L+S+ + IR + YKN+ + + ++ FP++ + + F+A + G+ ++ ++ E +N+ + +A I+ N D F+ +G P A + + + EL + +VV +LP ++ PR A R V + Y + + I+ ++S LE N ++K A V L + Y D+ +N+ EP ++ + + D F + + M+ + P+F + + E + +VDRS +M+G NIDRA+E +L+FLKSLP C F + +G+ + K+F S++ S A ++ +L A + PL ++Y ++ + + Y R FL+T G V N ++VT VRK+ + R FT+GI G V ++A+AG G V ++ V + D A V T+ + W P P ++PPI+ + L + ++ N S V K T+S S + V F+ N VD + +HRL AK I E ++ + SG + ++ LS NI++K TTFVA+D+
Sbjct: 4 YGLLDKAVGSSVPLESVWIRAVIRGFTAHVLATLEYKNNSSNPLDAIYVFPVDDHAAICGFQATIDGRSVVAAVQDRGEVLKQNIDSARSTQNGLAVNIDDNA---DNFQIGVGILPSYKTAVLQVTYVAELPVGK-DGQVV----FILPSVINPRVFQEHDARKKNLGRRTASVNSKYSFELDLKVQSATSIQEITSPCGGLEYEINASDKRQASVRLTGESYHFNDDVQVNV---IRSEPFQLHALTENGVTTKSSD---KFLATPIVMLNYFPEFTDC--KERTRGEFIFLVDRSKNMKGENIDRAREVVLLFLKSLPDGCHFNVISYGASYIKLFTQSEVCDHSSRERASDFVWDLKAGIDNARPIDPLREVYSHNLIDTGYPRQVFLVTGGEVGNAEQVTDEVRKNAHTARCFTLGINVGKHSDHVRRIARAGRGTCELVSQLDRVAPKVQSMWDEATQPV-VTNFHVSWTLPDGWVARCIPYNLPPIYRGHTLILYGLLMREDNKQPSYIVAVEGKATISASIQHGDTTKDVHQEVRFSALSGNP---VDRDIFLHRLTAKALIEEEEDKRVWNLTSGGLATRAPIVSLSKSTNIISKATTFVAVDK 596
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Nematostella
Match: EDO37524 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFM5]) HSP 1 Score: 135.191 bits (339), Expect = 4.931e-34 Identity = 116/439 (26.42%), Postives = 186/439 (42.37%), Query Frame = 2
Query: 35 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKK----IIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDL-LLPLILRPRYTPPE---------YAGDREVFQVTNH----YEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKD--LDININYLAMKEPSVVYEVGSSSPLYS-GKDAQGS---------FYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTR 1261
M GL LK+ S+ + + Y N D EGLF FP + V EA V + I + K++Y V + + D+F IG P + FA L+ + S+ R L +LP + PR + E Y + + Y + + + ++ SS H +++ ++ ++ +H+ T D L + ++ +P V+ E G + S +D + S F M+ + P SL ++ E + +VDRSGSM G +I + KE L++FLKSLP C F + GFGS + V+ ++Q+Y + + A NY + + A+ GGT L+ PLE ++N R F+LTDG VSN EV VR++ STR
Sbjct: 1 MTGLVNRHTSYPLQLKASSIFAEVNGFAARVLATLTYYNQCEYDVEGLFVFPQDERTTVVELEATVEERHVYTDIRAQTGQKSTEKSVYSVEERED-------------DLFSLSIGRIPAHCSV-----FAQVTLLTELISDRKTRGSLFILPSVFTPRLSTDEDEQLDSHDLYGSQMLISDIPRKTLEPYSFELQLEVAAPCLLAGCSSPTHAIQVDADSKATNASSIHITIAEPHTYDCELVVLLHLSHPNDPYVLIEEGKKERVDSVEQDVEKSPVPTNLVEEFTKKPSIMINYTP----SLTSSSQIAEFIFLVDRSGSMSGKHIFQVKEMLILFLKSLPANCYFNLIGFGSYYRSVYQETQIYDEETAEHACNYVQKMRADLGGTNLILPLEFIFNQPPKKGIPRFVFMLTDGGVSNTTEVIDFVRRNAYSTR 417
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Nematostella
Match: EDO46659 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPC2]) HSP 1 Score: 109.768 bits (273), Expect = 2.021e-24 Identity = 144/610 (23.61%), Postives = 241/610 (39.51%), Query Frame = 2
Query: 62 DQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYH----------------SDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMY----NSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKS-TRLF---TVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAE--------QIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQ 1795
D+ LK++ + + +L + Y N+ + E + FP++ V FEA + GK IIG KE E+A+ Y A GH A ++++ T DVF +GN P + I + + EL V E++ LP + P +Q T ++ + ++ V E S N + + S E+ + + D+ + + K V E+ L SG Q S M+ F P+F+S ++ E++ V+D S SM+G + AK+ L+ L + F I FGS + ++F SQ ++ A + K++ A G T+L R L +Y NS +DY FL TDG+V+ + +R + R F +G G + L D K+ + V +LS + +L T K+ W QH S P P F + ++ G+ V CT +H+L A+ I + E + E + +K +I LS + +IV+++T+FVAI+
Sbjct: 401 DKPVPLKAVHIRAKLLDLAAQVVVMQAYCNNSDVPIEAKYVFPLDDMAAVCGFEAFINGKHIIGEVKEKEQARKEYREAISAGHGAYLMDEETP--DVFTVNVGNLPPAASVLIKITYVAELT---VEGELIC---FRLPGSVAP-------------WQRTQAHDDVTQTDVDTICVDEENQS---------NTSVQVSVEMPFEIRAILCPGHDVKVKRTSTK---AVVEMAPGGTLGSGFQLQIQLAEIHVPRMWVERHDTEADSQACMLAFYPEFESGPPHH---VEVIFVLDASCSMKGKALQEAKKLTLMCLSLMEEEWAFNIVVFGSNYSELFTQSQKKDKETVARAAKFVKSVKAVKGSTDLWRVLRSLYLLRCNS--TADYPSNVFLFTDGHVTEESTTLAYIRDIRPTCNRHFLRSMARVGAG-AYELFDSKVKSKWERKV----ESQLSKARQPVL---------TSVKVAWQ--QHDSYAKPPVQAPHDIVSLFNGSRQVVYGL----VDNCTQV--------------------------LHQLTARAIIRDWEEGSLDPNHTKHEMAKRDMKDFIISLSKRFSIVSQFTSFVAIEH 926
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Medaka
Match: ENSORLT00000017719.2 (von Willebrand factor A domain-containing protein 5A [Source:NCBI gene;Acc:101161821]) HSP 1 Score: 263.077 bits (671), Expect = 3.520e-75 Identity = 175/587 (29.81%), Postives = 292/587 (49.74%), Query Frame = 2
Query: 83 SLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKT-EIVIVVDRSGSMR---------GSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKI----NEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
S+ V+ +++ +++ Y+N ++ E LF FP+ + V +F A +G I+ KE ++A+ Y+ A G A ++E++ D+F +G+ P A I+L++ +EL V ++ RF LP +L PRY P + Y +F A ++ + + V S + + NT+ T A V L + + +D+++ I Y +PS V E G S G+ V MV P+F S+M+ + E V +VDRSGSM+ + I A++ LL+ LKSLP+ C F IYGFGS++D +F S YS+ S+ AL + + A+ GGTE+++PL+ +Y+ S+ R F+ TDG V N EV LVRK+ S R F+ GIG+G S +L++ +A+ G G + F+ + + A VM+ L A+ V D + W P+ VS I IF + ++G S T++ + P + N + D VHRL A+ I +E E E +K+ +++LS+Q + + +T F+A+++D
Sbjct: 23 SVEVELQVKDHVATVISTLNYQNKEDKPIEALFVFPLPGDAAVCHFSADIGQTHIVAELKEKQQAREEYDDALSSGQQAFLLEESEQSPDIFSLSVGSLPPGESASIMLQYVIELA---VEADGALRF--CLPAVLNPRYQPQGPGVPVSSVPASEIPYSLSFSARVSSPRPVSKVESSCSLEPLQYLNTDHTEAAVKLAAGHKFDRDVELLIYYKDAHQPSAVVEAGQDS------AKPGTLMGDPVVMVSLYPEFPESVMSKRASCGEFVFLVDRSGSMQCPTNNWNQQETRISSARDTLLLLLKSLPMGCYFNIYGFGSRYDHIFPKSVEYSEKSMEEALKKVEVMQADLGGTEILQPLQHIYSQPCISNQPRQLFVFTDGEVGNTKEVLDLVRKNAGSHRCFSFGIGEGASSALINGLAQEGRGHAQFITGSDRMQAKVMQSLKFALQPV-VKDISVTWDLPKGVSATVLSPPITTIFQGQRSLVYAQLSGKSSQTDCSVTVNYTLGDHPYESKQQF-NLNPAKDTGLTVHRLAARILIRSLESEERENRGKSNEDMKRKVVELSVQSGVSSHHTAFIAVNKD 596
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Medaka
Match: ENSORLT00000029480.1 (pep primary_assembly:ASM223467v1:13:27928104:27975128:-1 gene:ENSORLG00000022184.1 transcript:ENSORLT00000029480.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 246.899 bits (629), Expect = 1.511e-69 Identity = 172/586 (29.35%), Postives = 286/586 (48.81%), Query Frame = 2
Query: 86 LSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGD----REVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKT-EIVIVVDRSGSMRGSN---------IDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEET-LKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
+ V+ +++ +++ Y+N ++ E LF FP+ + V +F A +G I+ KE ++A+ Y+ A G A ++E++ D+F +G+ P A I L++ +EL V ++ RF LP +L PRY P G V Y +F A ++ + + V S + + NT+ T A V L + + +D+++ I Y +PS V E G S G+ V MV P+F S+M+ + E V ++DRSGSMR S I A++ LL+ LKSLP+ C F IYGFGS++D++F S Y++ S+ AL K + A+ GGTE+++PL+ +Y+ S+ R F+ TDG V N EV LVRK+ S R F+ GIG+G S +L++ +A+ G G + F+ + + A VM+ L A+ V D + W P+ VS I IF G +S +I L G + D +V +L + + E ++ E + +K+ ++ LS+Q + + +T F+A+++D
Sbjct: 13 VEVELQVKDHVATVISTLNYQNKEDKPIEALFVFPLPGDAAVCHFSADIGQTHIVAELKEKQQAREEYDDALSSGQQAFLLEESEQSPDIFSLSVGSLPPGESASIRLQYVIELA---VEADGALRF--CLPAVLNPRYQPQGSEGPGVPVSSVPASEIPYSLSFSARVSSPRPVSKVESSCSLEPLQYLNTDHTEAAVKLAAGHKFDRDVELLIYYKDAHQPSAVVEAGQDS------AKPGTLMGDPVVMVSLYPEFPESVMSKRTSCGEFVFLLDRSGSMRCSTSNWNQQETCISSARDTLLLLLKSLPMGCYFNIYGFGSRYDQIFPKSVEYNEKSMEEALKKVKVMQADLGGTEILQPLQHIYSQPCISNQPRQLFVFTDGEVGNTKEVLDLVRKNAGSHRCFSFGIGEGASSALINGLAQEGRGHAQFITGSDRMQAKVMQSLKFALQPV-VKDISVTWDLPKRVSATVLSPPITTIF-----------QGQRS--LIYAQLCGKV----------LDKKDRQTRNHLKVCQLETQSRFIEARKKSEGNQHKDMKRKVVKLSVQSGVSSHHTAFIAVNKD 563
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Medaka
Match: ENSORLT00000017722.2 (von Willebrand factor A domain-containing protein 5A-like [Source:NCBI gene;Acc:105355516]) HSP 1 Score: 240.35 bits (612), Expect = 1.175e-67 Identity = 174/583 (29.85%), Postives = 283/583 (48.54%), Query Frame = 2
Query: 77 LKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGD----REVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQ-GSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKIN--EMAEQIESGE--ETLKKDLIDLSLQVNIVTKYTTFVAIDQD 1798
LKS+ V+ +++ +++ Y+N ++ E LF FP+ + V +F A +G I+ KE ++A+ Y+ A G A ++E++ D+F +G+ P A I+L++ +EL V ++ RF LP +L PRY P G V Y +F A ++ + + V S + + NT+ T A V L + + +D+++ I Y +PS V E G S AQ G+ V MV P+F S+M S R S + + LL+ LKSLP+ C F IYGFGS +D +F S YS+ S+ AL + + A+ GGTE+++PL+ +Y+ S+ R F+ TDG V N EV LVRK+ S R F+ GIG+G S +L++ +A+ G G + F+ + + A VM+ L A+ V D + W P+ VS I IF + + G +++ L S S T +F VHRL A+ I E E+ G+ E +K+ +++LS+Q + + +T F+A+++D
Sbjct: 16 LKSVEVELQVKDHVATVISTLNYQNKEDKPIEALFVFPLPGDAAVCHFSADIGQTHIVAELKEKQQAREEYDDALSSGQQAFLLEESEQSPDIFSLSVGSLPPGESASIMLQYVIELA---VEADGALRF--CLPAVLNPRYHPQGSEGPGVPVSSVPASEIPYSLSFSARVSSPRPVSKVESSCSLEPLHYLNTDHTEAAVKLAAGHKFDRDVELLIYYKDAHQPSAVVEAGQDS-------AQPGTLMGDPVVMVSLYPEFPESVM----------------SKRASCGEFCSDTLLLLLKSLPMGCYFNIYGFGSSYDHIFPQSVEYSEKSMEEALKKVEVMQADLGGTEILQPLQHIYSQPCISNQPRQLFVFTDGEVGNTKEVLDLVRKNAGSHRCFSFGIGEGASSALINGLAQEGRGHAQFITGSDRMQAKVMQSLKFALQLV-VKDISVTWDLPKGVSATVLSPPITTIFQGQRSLVYAQLCGKV---LVRSPLEKS------SLTI-----------QFTVHRLAARILIRSLESEERKNRGKSNEDMKRKVVELSVQSGVSSHHTAFIAVNKD 549 HSP 2 Score: 53.5286 bits (127), Expect = 1.126e-6 Identity = 30/104 (28.85%), Postives = 58/104 (55.77%), Query Frame = 3
Query: 2034 DSVDGYMETKSMPKIET--KEKRKDIIMFLVDLQNINGSWNYDEKIFAYIGIDVNRIKEIQPDKISDIIWST--AVIYQHLMIKEQAREKEWRLFARKAKEWIE 2333
D+V G + +++P ++ R+D ++ LV LQ +G W D + + +G +++ +P ++S +W+T A+I+ H K A++ EW L A KA W++
Sbjct: 552 DAVQGPLVCRNVPTPAAVPEQPRRDPLLQLVSLQKASGCWLLDTALASVLGKTSEEVEKSKPAEVSSEVWATILALIWLH-GFKMDAKD-EWELLAVKAASWVQ 653
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Medaka
Match: ENSORLT00000017644.2 (von Willebrand factor A domain-containing protein 5A [Source:NCBI gene;Acc:101161821]) HSP 1 Score: 237.654 bits (605), Expect = 1.391e-66 Identity = 153/495 (30.91%), Postives = 250/495 (50.51%), Query Frame = 2
Query: 83 SLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTN-HYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKT-EIVIVVDRSGSMR---------GSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMING 1534
S+ V+ +++ +++ Y+N ++ E LF FP+ + V +F A +G I+ KE ++A+ Y+ A G A ++E++ D+F +G+ P A I+L++ +EL V ++ RF LP +L PRY P + Y +F A ++ + + V S + + NT+ T A V L + + +D+++ I Y +PS V E G S G+ V MV P+F S+M+ + E V +VDRSGSM+ + I A++ LL+ LKSLP+ C F IYGFGS++D +F S YS+ S+ AL + + A+ GGTE+++PL+ +Y+ S+ R F+ TDG V N EV LVRK+ S R F+ GIG+G S +L++ +A+ G G + F+ + + A VM+ L A+ V D + W P+ VS I IF + ++G
Sbjct: 23 SVEVELQVKDHVATVISTLNYQNKEDKPIEALFVFPLPGDAAVCHFSADIGQTHIVAELKEKQQAREEYDDALSSGQQAFLLEESEQSPDIFSLSVGSLPPGESASIMLQYVIELA---VEADGALRF--CLPAVLNPRYQPQGPGVPVSSVPASEIPYSLSFSARVSSPRPVSKVESSCSLEPLQYLNTDHTEAAVKLAAGHKFDRDVELLIYYKDAHQPSAVVEAGQDS------AKPGTLMGDPVVMVSLYPEFPESVMSKRASCGEFVFLVDRSGSMQCPTNNWNQQETRISSARDTLLLLLKSLPMGCYFNIYGFGSRYDHIFPKSVEYSEKSMEEALKKVEVMQADLGGTEILQPLQHIYSQPCISNQPRQLFVFTDGEVGNTKEVLDLVRKNAGSHRCFSFGIGEGASSALINGLAQEGRGHAQFITGSDRMQAKVMQSLKFALQPV-VKDISVTWDLPKGVSATVLSPPITTIFQGQRSLVYAQLSG 505
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Medaka
Match: ENSORLT00000042884.1 (von Willebrand factor A domain-containing protein 5A [Source:NCBI gene;Acc:101174937]) HSP 1 Score: 237.269 bits (604), Expect = 9.196e-66 Identity = 181/610 (29.67%), Postives = 297/610 (48.69%), Query Frame = 2
Query: 35 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGD----REVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQ-GSFYHSDVAMVKFLPKFDSSLMNNQCKT-EIVIVVDRSGSM--------RGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGM--KSGD---VIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKIN--EMAEQIESGE--ETLKKDLIDLSLQVNIVTKYTTFVAIDQ 1795
+FGL + QK LKS+ V+ +++ +++ Y+N ++ E LF FP+ + V +F A +G I+ KE ++A+ Y+ A G A ++E++ D+F +G+ P A I L++ +EL V ++ RF LP +L PRY P G V Y +F + ++ + + V S + + NT+ T A V L + + +D+++ I Y +PS V E G S AQ G+ V M F P F S+ ++ E V ++DRSGSM + ID AKE LL+ LKSLP+ C F IY FG +F+ +F S YS ++ AL + + A+ GGT+++ PL+ +Y R F+ TDG VSN E+ LV+++ S R F+ GIG G S +LV+ +AK G G + F+ + + M+ L +A+ D L W P V+ +I IF F + G K+G+ +K +++G + + + + + D VH L A I EM E+ GE E +KK L+++S++ + + +T F+A+D+
Sbjct: 4 LFGLVSCER-QKVPLKSVEVELQVKDHVATVISTLNYQNKEDKPIEALFVFPLPGDAAVCHFSADIGQTHIVAELKEKQQAREEYDDALSSGQQAFLLEESEQNPDIFSLSVGSLPPGESASIRLQYVIELA---VEADGALRF--CLPAVLNPRYQPQGSEGPGVPVSSVPASEIPYSLSFSSRVSSPRPVSKVESSCSLEPLHYLNTDHTEAAVKLAAGHKFDRDVELLIYYKDAHQPSAVVEAGQDS-------AQPGTLMGDPVVMASFYPNFPESVQSSSSSCGEFVFLLDRSGSMDFPMADIHHRTRIDSAKETLLLLLKSLPMGCYFNIYSFGDRFEHLFQKSLRYSQKTMKQALKKVEEMSADLGGTDILEPLQHIYRQSCIRGQPRQLFVFTDGEVSNTKEILDLVKENCASYRCFSFGIGPGASSALVNGMAKEGGGHAQFITDNDRMQLKAMQSLRLALQPS-VEDISLTWDLPAGVTAKVLSPTIQNIFQGQRSVVFAQLTGQSSKTGEGSLTVKYSIAGHSCQNQLFLSLKPAPMGSCTD-SLTVHHLAALTLIRRLEMEERGCEGEQSEGVKKKLVEVSVESGVSSAFTAFIAVDK 598
BLAST of vault protein inter alpha trypsin-1 vs. Planmine SMEST
Match: SMESG000053657.1 (SMESG000053657.1) HSP 1 Score: 1202.19 bits (3109), Expect = 0.000e+0 Identity = 587/601 (97.67%), Postives = 592/601 (98.50%), Query Frame = 2
Query: 35 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRP-RYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTCITD 1834
MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVF+CRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRP EYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSS LYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNS+LPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGD+IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEE+LKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVT I +
Sbjct: 1 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFRCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPDTLHQVEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSSLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSHLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDLIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEESLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTNIEE 601
BLAST of vault protein inter alpha trypsin-1 vs. Planmine SMEST
Match: SMESG000053671.1 (SMESG000053671.1) HSP 1 Score: 1201.81 bits (3108), Expect = 0.000e+0 Identity = 582/603 (96.52%), Postives = 591/603 (98.01%), Query Frame = 2
Query: 35 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEV--VDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTCITDD 1837
MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFP+EYNCIVYYFEALVGGKKIIG+CKEIEEAKNLYEVAKEKGHMAAIIE+NTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEV VDRFDL LPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEI FNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMV FLPKFDSSLMNNQCKTEIVIVVDRSGSM GSNIDRAKECLLIFLKSLPVYCKFQIYGFGS+FDK FNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDG+V NQDEVTKLVRKHNKSTRLFTVGIGDGVS SLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEP+SFT EIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEE+LKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVT I ++
Sbjct: 1 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPLEYNCIVYYFEALVGGKKIIGVCKEIEEAKNLYEVAKEKGHMAAIIEQNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVEGVDRFDLSLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIVFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVNFLPKFDSSLMNNQCKTEIVIVVDRSGSMHGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSEFDKAFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGDVGNQDEVTKLVRKHNKSTRLFTVGIGDGVSTSLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPISFTIEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEESLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTNIEEE 603 HSP 2 Score: 103.605 bits (257), Expect = 2.915e-22 Identity = 65/184 (35.33%), Postives = 98/184 (53.26%), Query Frame = 3
Query: 1803 QVNLWSHALLMMGAPQMMCDMYVXXXXXXAMRCSAFGLMSSXXXXXXQYSAMKEQVAIEDFYDDMDCSDNLEAYGCFDSVDGYMETKSMPKIETKEKRK-DIIMFLVDLQNINGSWNYDEKIFAYIGIDVNRIKEIQPDKISDIIWSTAVIYQHLMIKEQAREKEWRLFARKAKEWIEQNLNDS 2351
++N L+ GAPQ++ D Y P PP M+C S + S KE + +D N+ +G S S + E D+I++LVD QNINGSWN++E I IG+++ + P +IS+ +W T IYQ+ ++KE +REKEWRL A+KAK WIE+++ +S
Sbjct: 612 RMNFQCVPLMKAGAPQIVYDRY--EPNPPPMKCPEAKFKKSK-----RTSLKKEDIGY------LDKIKNMFYFGKKASKQNRKSKDSSSEEAVSEPEPVDVIIYLVDKQNINGSWNFNESILLKIGVNITEFRNKMPGRISEEVWITVAIYQYFVLKESSREKEWRLVAKKAKNWIEKSIAES 782
BLAST of vault protein inter alpha trypsin-1 vs. Planmine SMEST
Match: SMESG000053671.1 (SMESG000053671.1) HSP 1 Score: 1199.88 bits (3103), Expect = 0.000e+0 Identity = 582/603 (96.52%), Postives = 591/603 (98.01%), Query Frame = 2
Query: 35 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEV--VDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTCITDD 1837
MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFP+EYNCIVYYFEALVGGKKIIG+CKEIEEAKNLYEVAKEKGHMAAIIE+NTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEV VDRFDL LPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEI FNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMV FLPKFDSSLMNNQCKTEIVIVVDRSGSM GSNIDRAKECLLIFLKSLPVYCKFQIYGFGS+FDK FNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDG+V NQDEVTKLVRKHNKSTRLFTVGIGDGVS SLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEP+SFT EIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEE+LKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVT I ++
Sbjct: 1 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPLEYNCIVYYFEALVGGKKIIGVCKEIEEAKNLYEVAKEKGHMAAIIEQNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVEGVDRFDLSLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIVFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVNFLPKFDSSLMNNQCKTEIVIVVDRSGSMHGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSEFDKAFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGDVGNQDEVTKLVRKHNKSTRLFTVGIGDGVSTSLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPISFTIEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEESLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTNIEEE 603 HSP 2 Score: 102.064 bits (253), Expect = 7.232e-22 Identity = 42/84 (50.00%), Postives = 63/84 (75.00%), Query Frame = 3
Query: 2100 DIIMFLVDLQNINGSWNYDEKIFAYIGIDVNRIKEIQPDKISDIIWSTAVIYQHLMIKEQAREKEWRLFARKAKEWIEQNLNDS 2351
D+I++LVD QNINGSWN++E I IG+++ + P +IS+ +W T IYQ+ ++KE +REKEWRL A+KAK WIE+++ +S
Sbjct: 685 DVIIYLVDKQNINGSWNFNESILLKIGVNITEFRNKMPGRISEEVWITVAIYQYFVLKESSREKEWRLVAKKAKNWIEKSIAES 768
BLAST of vault protein inter alpha trypsin-1 vs. Planmine SMEST
Match: SMESG000053669.1 (SMESG000053669.1) HSP 1 Score: 1199.88 bits (3103), Expect = 0.000e+0 Identity = 582/602 (96.68%), Postives = 590/602 (98.01%), Query Frame = 2
Query: 35 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEV--VDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTCITD 1834
MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFP+EYNCIVYYFEALVGGKKIIG+CKEIEEAKNLYEVAKEKGHMAAIIE+NTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEV VDRFDL LPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEI FNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMV FLPKFDSSLMNNQCKTEIVIVVDRSGSM GSNIDRAKECLLIFLKSLPVYCKFQIYGFGS+FDK FNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDG+V NQDEVTKLVRKHNKSTRLFTVGIGDGVS SLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAF MINGMKSGDVIKCTLSGSANGEP+SFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEE+LKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVT I +
Sbjct: 1 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPLEYNCIVYYFEALVGGKKIIGVCKEIEEAKNLYEVAKEKGHMAAIIEQNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVEGVDRFDLSLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIVFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVNFLPKFDSSLMNNQCKTEIVIVVDRSGSMHGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSEFDKAFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGDVGNQDEVTKLVRKHNKSTRLFTVGIGDGVSTSLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFSMINGMKSGDVIKCTLSGSANGEPISFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEESLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTNIEE 602
BLAST of vault protein inter alpha trypsin-1 vs. Planmine SMEST
Match: SMESG000053657.1 (SMESG000053657.1) HSP 1 Score: 1162.13 bits (3005), Expect = 0.000e+0 Identity = 569/600 (94.83%), Postives = 575/600 (95.83%), Query Frame = 2
Query: 35 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFKCRIGNFPKNSEAKIILKFAMELKLSPVRSEVVDRFDLLLPLILRPRYTPPEYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSPLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSYLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDVIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEETLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTCITD 1834
MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVF+CRIGNFPKNSEAKIILKFAMELKLSPVR +YAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSS LYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNS+LPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGD+IKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEE+LKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVT I +
Sbjct: 1 MFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNDGNEDGEGLFSFPIEYNCIVYYFEALVGGKKIIGLCKEIEEAKNLYEVAKEKGHMAAIIEKNTSMLDVFRCRIGNFPKNSEAKIILKFAMELKLSPVR----------------------KYAGDREVFQVTNHYEYNFKAVINGTKVIENVSSVNHTLEIAFNNTNKTSAEVHLKSKYDGTKDLDININYLAMKEPSVVYEVGSSSSLYSGKDAQGSFYHSDVAMVKFLPKFDSSLMNNQCKTEIVIVVDRSGSMRGSNIDRAKECLLIFLKSLPVYCKFQIYGFGSQFDKVFNDSQLYSDHSIGIALNYQKNLDANFGGTELMRPLEDMYNSHLPSDYSRLAFLLTDGNVSNQDEVTKLVRKHNKSTRLFTVGIGDGVSISLVDQVAKAGLGKSVFVRNAKELSASVMELLDIAMNSVPFTDAKLEWHCPQHVSIVTAPKSIPPIFSDYFLTAFCMINGMKSGDLIKCTLSGSANGEPVSFTTEIRNTDAFVDEEFRVHRLLAKYKINEMAEQIESGEESLKKDLIDLSLQVNIVTKYTTFVAIDQDAPGEPLVTNIEE 578 The following BLAST results are available for this feature:
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of vault protein inter alpha trypsin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of vault protein inter alpha trypsin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of vault protein inter alpha trypsin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of vault protein inter alpha trypsin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30005772 ID=SMED30005772|Name=vault protein inter alpha trypsin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2882bpback to top protein sequence of SMED30005772-orf-1 >SMED30005772-orf-1 ID=SMED30005772-orf-1|Name=SMED30005772-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=189bp MMGAPQMMCDMYVPPPPPPAMRCSAFGLMSSPPAPPPQYSAMKEQVAIEDback to top protein sequence of SMED30005772-orf-2 >SMED30005772-orf-2 ID=SMED30005772-orf-2|Name=SMED30005772-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=659bp VSQFEILNITTMFGLCPLKYDQKFSLKSLSVDCNIRNLLSSCTCEFVYKNback to top Annotated Terms
The following terms have been associated with this transcript:
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