Cell number regulator 7

Overview


Name	Cell number regulator 7
Smed ID	SMED30005770
Length (bp)	670

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Cell number regulator 7 (SMED30005770) t-SNE clustered cells

Violin plots show distribution of expression levels for Cell number regulator 7 (SMED30005770) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cell number regulator 7 (SMED30005770) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cell number regulator 7 (SMED30005770) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30005770

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30005770	SMESG000032490.1	Contig671	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30005770	SMESG000060415.1	Contig671	GPL15192	PMID:23079596 Forsthoefel et al., 2012
pharynx	SMED30005770	SMESG000060415.1	dd_Smed_v4_743_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30005770	SMESG000060415.1	dd_Smed_v4_743_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30005770	SMESG000060415.1	dd_Smed_v4_743_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30005770	SMESG000060415.1	dd_Smed_v4_743_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30005770	SMESG000060415.1	dd_Smed_v4_743_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30005770	SMESG000060415.1	dd_Smed_v4_743_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30005770	SMESG000060415.1	dd_Smed_v4_743_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30005770	SMESG000060415.1	dd_Smed_v4_743_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
intestinal phagocyte	SMED30005770	SMESG000060415.1	dd_Smed_v6_743_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Human
Match: PLAC8 (placenta associated 8 [Source:HGNC Symbol;Acc:HGNC:19254])

HSP 1 Score: 60.8474 bits (146), Expect = 1.594e-11
Identity = 38/103 (36.89%), Postives = 49/103 (47.57%), Query Frame = 3

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSM 359
                WQ G+C CF DCG+CL   FC PC  +G    A    CCLCG          T   +R+  R R  IPGS  +D+   L CP CT  Q+ ++     +M
Sbjct:   22 QNSNWQTGMCDCFSDCGVCLCGTFCFPC--LGCQVAADMNECCLCG----------TSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDINRRRAM 112

[Close]

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSM 359
                WQ G+C CF DCG+CL   FC PC  +G    A    CCLCG          T   +R+  R R  IPGS  +D+   L CP CT  Q+ ++     +M
Sbjct:   22 QNSNWQTGMCDCFSDCGVCLCGTFCFPC--LGCQVAADMNECCLCG----------TSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDINRRRAM 112

[Close]

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSM 359
                WQ G+C CF DCG+CL   FC PC  +G    A    CCLCG          T   +R+  R R  IPGS  +D+   L CP CT  Q+ ++     +M
Sbjct:   22 QNSNWQTGMCDCFSDCGVCLCGTFCFPC--LGCQVAADMNECCLCG----------TSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDINRRRAM 112

[Close]

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSM 359
                WQ G+C CF DCG+CL   FC PC  +G    A    CCLCG          T   +R+  R R  IPGS  +D+   L CP CT  Q+ ++     +M
Sbjct:   22 QNSNWQTGMCDCFSDCGVCLCGTFCFPC--LGCQVAADMNECCLCG----------TSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDINRRRAM 112

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Zebrafish
Match: ponzr10 (plac8 onzin related protein 10 [Source:ZFIN;Acc:ZDB-GENE-081107-68])

HSP 1 Score: 46.595 bits (109), Expect = 3.463e-6
Identity = 37/113 (32.74%), Postives = 49/113 (43.36%), Query Frame = 3

Query:   33 QMSDSDYHEYYWQHGLCSCFDDCGLCLVSFF-CPCYTVGMDAKAVGESCCLCGFATITPAAI------FTVPLI----RSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            Q   S   E  W  G+C CF D   C  +++ CPC+     A   GES CL     + PA +      F VP +    R  IR +  I GS   D  V   C  C+  QM++E
Sbjct:    7 QQVPSKPQETLWNSGICDCFQDLNSCCYAYWCCPCFACS-TAGEFGESTCLPLVDILGPAVMASFGVAFCVPPVTMSLRVAIRHKYNIRGSICNDIAVSCCCVMCSWCQMNRE 118

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Zebrafish
Match: BX005027.2 (plac8 onzin related protein 10 [Source:NCBI gene;Acc:100001900])

HSP 1 Score: 46.595 bits (109), Expect = 3.545e-6
Identity = 37/113 (32.74%), Postives = 49/113 (43.36%), Query Frame = 3

Query:   33 QMSDSDYHEYYWQHGLCSCFDDCGLCLVSFF-CPCYTVGMDAKAVGESCCLCGFATITPAAI------FTVPLI----RSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            Q   S   E  W  G+C CF D   C  +++ CPC+     A   GES CL     + PA +      F VP +    R  IR +  I GS   D  V   C  C+  QM++E
Sbjct:    9 QQVPSKPQETLWNSGICDCFQDLNSCCYAYWCCPCFACS-TAGEFGESTCLPLVDILGPAVMASFGVAFCVPPVTMSLRVAIRHKYNIRGSICNDIAVSCCCVMCSWCQMNRE 120

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Xenopus
Match: paqr6 (progestin and adipoQ receptor family member VI [Source:Xenbase;Acc:XB-GENE-5863258])

HSP 1 Score: 49.2914 bits (116), Expect = 2.070e-7
Identity = 32/91 (35.16%), Postives = 41/91 (45.05%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            W    C C +D G+CL   F PC      AK  GE CCL       P    T   +R+ IR+R  I G+   D+   + C  CT  QM +E
Sbjct:   27 WSSDTCDCCNDAGICLCGAFVPCILACRVAKDYGECCCL-------PCLFGTSIAMRTGIRERYHIEGTICNDWACVMCCGPCTLCQMARE 110

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Xenopus
Match: eps15l1 (epidermal growth factor receptor pathway substrate 15-like 1 [Source:Xenbase;Acc:XB-GENE-959469])

HSP 1 Score: 49.2914 bits (116), Expect = 2.070e-7
Identity = 32/91 (35.16%), Postives = 41/91 (45.05%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            W    C C +D G+CL   F PC      AK  GE CCL       P    T   +R+ IR+R  I G+   D+   + C  CT  QM +E
Sbjct:   27 WSSDTCDCCNDAGICLCGAFVPCILACRVAKDYGECCCL-------PCLFGTSIAMRTGIRERYHIEGTICNDWACVMCCGPCTLCQMARE 110

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Xenopus
Match: paqr6 (progestin and adipoQ receptor family member VI [Source:Xenbase;Acc:XB-GENE-5863258])

HSP 1 Score: 49.2914 bits (116), Expect = 2.311e-7
Identity = 32/91 (35.16%), Postives = 41/91 (45.05%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            W    C C +D G+CL   F PC      AK  GE CCL       P    T   +R+ IR+R  I G+   D+   + C  CT  QM +E
Sbjct:   30 WSSDTCDCCNDAGICLCGAFVPCILACRVAKDYGECCCL-------PCLFGTSIAMRTGIRERYHIEGTICNDWACVMCCGPCTLCQMARE 113

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Xenopus
Match: eps15l1 (epidermal growth factor receptor pathway substrate 15-like 1 [Source:Xenbase;Acc:XB-GENE-959469])

HSP 1 Score: 49.2914 bits (116), Expect = 2.455e-7
Identity = 32/91 (35.16%), Postives = 41/91 (45.05%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            W    C C +D G+CL   F PC      AK  GE CCL       P    T   +R+ IR+R  I G+   D+   + C  CT  QM +E
Sbjct:   30 WSSDTCDCCNDAGICLCGAFVPCILACRVAKDYGECCCL-------PCLFGTSIAMRTGIRERYHIEGTICNDWACVMCCGPCTLCQMARE 113

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Xenopus
Match: abtb1 (ankyrin repeat and BTB (POZ) domain containing 1 [Source:Xenbase;Acc:XB-GENE-976579])

HSP 1 Score: 48.1358 bits (113), Expect = 5.056e-7
Identity = 31/95 (32.63%), Postives = 43/95 (45.26%), Query Frame = 3

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            +   W   +  C +D G+CL   F PC      ++  GE CCL       P    +V  +R+ IR+R  I GS   D+    FC  CT  QM +E
Sbjct:   19 NSSQWNSDVFDCCEDMGICLCGTFVPCILACKVSQDFGECCCL-------PCLFGSVLAVRTGIRERYHIEGSICNDWVCLSFCGQCTLCQMARE 106

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Mouse
Match: Plac8 (placenta-specific 8 [Source:MGI Symbol;Acc:MGI:2445289])

HSP 1 Score: 63.929 bits (154), Expect = 7.058e-13
Identity = 38/104 (36.54%), Postives = 51/104 (49.04%), Query Frame = 3

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFCPCYT-VGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMS 362
                WQ  LC CF DCG+CL   F  C+T +G    A    CCLCG          T   +R+  R R  IPGS  +D+ V LFCP C+  Q+ ++     +M+
Sbjct:   19 QNSNWQTSLCDCFSDCGVCLCGTF--CFTCLGCQVAADMNECCLCG----------TTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRDINRRRAMN 110

[Close]

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFCPCYT-VGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMS 362
                WQ  LC CF DCG+CL   F  C+T +G    A    CCLCG          T   +R+  R R  IPGS  +D+ V LFCP C+  Q+ ++     +M+
Sbjct:   19 QNSNWQTSLCDCFSDCGVCLCGTF--CFTCLGCQVAADMNECCLCG----------TTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRDINRRRAMN 110

[Close]

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFCPCYT-VGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMS 362
                WQ  LC CF DCG+CL   F  C+T +G    A    CCLCG          T   +R+  R R  IPGS  +D+ V LFCP C+  Q+ ++     +M+
Sbjct:   19 QNSNWQTSLCDCFSDCGVCLCGTF--CFTCLGCQVAADMNECCLCG----------TTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRDINRRRAMN 110

[Close]

BLAST of Cell number regulator 7 vs. UniProt/SwissProt
Match: sp|Q9JI48|PLAC8_MOUSE (Placenta-specific gene 8 protein OS=Mus musculus OX=10090 GN=Plac8 PE=1 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 4.937e-12
Identity = 38/104 (36.54%), Postives = 51/104 (49.04%), Query Frame = 3

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFCPCYT-VGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMS 362
                WQ  LC CF DCG+CL   F  C+T +G    A    CCLCG          T   +R+  R R  IPGS  +D+ V LFCP C+  Q+ ++     +M+
Sbjct:   19 QNSNWQTSLCDCFSDCGVCLCGTF--CFTCLGCQVAADMNECCLCG----------TTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRDINRRRAMN 110

[Close]

BLAST of Cell number regulator 7 vs. UniProt/SwissProt
Match: sp|Q9NZF1|PLAC8_HUMAN (Placenta-specific gene 8 protein OS=Homo sapiens OX=9606 GN=PLAC8 PE=2 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 7.654e-11
Identity = 38/103 (36.89%), Postives = 49/103 (47.57%), Query Frame = 3

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSM 359
                WQ G+C CF DCG+CL   FC PC  +G    A    CCLCG          T   +R+  R R  IPGS  +D+   L CP CT  Q+ ++     +M
Sbjct:   22 QNSNWQTGMCDCFSDCGVCLCGTFCFPC--LGCQVAADMNECCLCG----------TSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDINRRRAM 112

[Close]

BLAST of Cell number regulator 7 vs. UniProt/SwissProt
Match: sp|Q5REK4|PLAC8_PONAB (Placenta-specific gene 8 protein OS=Pongo abelii OX=9601 GN=PLAC8 PE=3 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 3.443e-10
Identity = 37/103 (35.92%), Postives = 48/103 (46.60%), Query Frame = 3

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSM 359
                WQ G+C CF DCG+CL   FC PC  +G    A    CCLCG          T   +R+  R R  IPGS  +D+     CP CT  Q+ ++     +M
Sbjct:   22 QNSNWQTGMCDCFSDCGVCLCGTFCFPC--LGCQVAADMNECCLCG----------TSVAMRTLYRTRYGIPGSICDDYMATFCCPHCTLCQIKRDINRRRAM 112

[Close]

BLAST of Cell number regulator 7 vs. UniProt/SwissProt
Match: sp|Q3ZCB2|PLAC8_BOVIN (Placenta-specific gene 8 protein OS=Bos taurus OX=9913 GN=PLAC8 PE=3 SV=1)

HSP 1 Score: 55.0694 bits (131), Expect = 9.513e-9
Identity = 36/95 (37.89%), Postives = 45/95 (47.37%), Query Frame = 3

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
                WQ GLC CF DCG+CL   FC        A  + E CCLCG          T   +R+  R R  IPGS  +DF V   CP C+  Q+ ++
Sbjct:   23 QNSNWQTGLCDCFSDCGVCLCGTFCFTCLACQVASDMNE-CCLCG----------TSVAMRTLYRTRYGIPGSICDDFMVTHCCPLCSLCQIKRD 106

[Close]

BLAST of Cell number regulator 7 vs. UniProt/SwissProt
Match: sp|Q6DK99|CNFNB_XENLA (Cornifelin homolog B OS=Xenopus laevis OX=8355 GN=cnfn-b PE=3 SV=1)

HSP 1 Score: 48.521 bits (114), Expect = 2.258e-6
Identity = 32/95 (33.68%), Postives = 42/95 (44.21%), Query Frame = 3

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            +   W   +  C +D G CL   F PC      +K  GE CCL       P    +V  +R+ IR+R  I GS   D+    FC  CT  QM +E
Sbjct:   19 NSSQWNSDVFDCCEDMGTCLCGTFVPCILACKVSKDYGECCCL-------PCLFGSVLAVRTGIRERYHIEGSICNDWVCLSFCAPCTLCQMARE 106

[Close]

BLAST of Cell number regulator 7 vs. TrEMBL
Match: A0A267H0G2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011900g1 PE=4 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 1.279e-30
Identity = 54/105 (51.43%), Postives = 71/105 (67.62%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 380
            +QHGLC C DDC LC++++FCPCYT G +A+AVG SCCLCG   I        P+IR  IR+RQ I GS+ +D+C++LFC  C   Q  QE   F+  +Q+IERE
Sbjct:    8 FQHGLCGCLDDCSLCIITYFCPCYTFGRNAEAVGSSCCLCGVGLILGFGCIIGPMIRGKIRERQGIDGSFCKDWCIWLFCSFCALVQEAQEVKSFAIRAQSIERE 112

[Close]

BLAST of Cell number regulator 7 vs. TrEMBL
Match: A0A1I8JKZ3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018606g1 PE=4 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 1.456e-30
Identity = 54/105 (51.43%), Postives = 71/105 (67.62%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 380
            +QHGLC C DDC LC++++FCPCYT G +A+AVG SCCLCG   I        P+IR  IR+RQ I GS+ +D+C++LFC  C   Q  QE   F+  +Q+IERE
Sbjct:    8 FQHGLCGCLDDCSLCIITYFCPCYTFGRNAEAVGSSCCLCGVGLILGFGCIIGPMIRGKIRERQGIDGSFCKDWCIWLFCGFCALVQEAQEVKSFAIRAQSIERE 112

[Close]

BLAST of Cell number regulator 7 vs. TrEMBL
Match: A0A267EXF1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011533g1 PE=4 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 2.173e-30
Identity = 53/105 (50.48%), Postives = 71/105 (67.62%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 380
            +QHGLC C DDC +C++++FCPCYT G +A+AVG SCCLCG   I        P+IR  IR+RQ I GS+ +D+C++LFC  C   Q  QE   F+  +Q+IERE
Sbjct:    8 FQHGLCGCLDDCSICIITYFCPCYTFGRNAEAVGSSCCLCGLGLILGFGCIIGPMIRGKIRERQGIDGSFCKDWCIWLFCGFCALVQEAQEVKSFAIRAQSIERE 112

[Close]

BLAST of Cell number regulator 7 vs. TrEMBL
Match: A0A1I8HVT9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig016327g1 PE=4 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 1.163e-29
Identity = 51/105 (48.57%), Postives = 68/105 (64.76%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 380
            +QHGLC CFDDCGLC++++F PCYT G +A+AVG+SC LC             P++R  IR+RQ I GS++ DFCV+ FC  C   Q  QE   F+   Q++ERE
Sbjct:    4 FQHGLCGCFDDCGLCIITYFVPCYTFGKNAEAVGDSCMLCALGMACGLGFILGPIVRGKIRERQGIDGSFIGDFCVWFFCGLCALIQEGQEVKSFAMKGQSVERE 108

[Close]

BLAST of Cell number regulator 7 vs. TrEMBL
Match: A0A267GVB5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig020929g1 PE=4 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 7.068e-29
Identity = 52/105 (49.52%), Postives = 71/105 (67.62%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 380
            +QHGL +CFDDCGLCL+++  PCYT GM+A+AVGE+C +CG   +   +    P+IRS IR+RQ IPGS++ D C++ FC  C   Q   E   F++  Q IERE
Sbjct:    4 FQHGLFACFDDCGLCLITYLVPCYTFGMNAEAVGENCFVCGLGMVCGLSFILGPMIRSKIRERQGIPGSFMADCCIWFFCSFCALVQEGLEVKTFAARPQRIERE 108

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 46.9802 bits (110), Expect = 1.352e-6
Identity = 33/106 (31.13%), Postives = 47/106 (44.34%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCL----CGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAI 371
            W  G+C C +D G+C   F+CP   +    K  GE  CL      F  + P   ++   +RS +R+R  I GS  +D CV   C  C   Q+ +E        Q I
Sbjct:   24 WSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYS---MRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKYRRQQPQVI 126

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Cavefish
Match: plac8.1 (placenta associated 8 [Source:NCBI gene;Acc:103039126])

HSP 1 Score: 45.8246 bits (107), Expect = 2.290e-6
Identity = 35/97 (36.08%), Postives = 48/97 (49.48%), Query Frame = 3

Query:   51 YHEYYWQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            +    +Q GL  C DDC  C+  +FC PC    + A  +GE CCLCG           +P IRS  R +  I GS  +DFC+  FC  C   Q+ ++
Sbjct:   10 FARTEFQTGLFECCDDCCTCMYGYFCLPCLGCSI-ASDMGE-CCLCGLG---------MP-IRSVYRTKYNIKGSMCKDFCISQFCLPCAACQLKRD 94

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Cavefish
Match: plac8.1 (placenta associated 8 [Source:NCBI gene;Acc:103039126])

HSP 1 Score: 45.8246 bits (107), Expect = 2.607e-6
Identity = 35/92 (38.04%), Postives = 47/92 (51.09%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
            +Q GL  C DDC  C+  +FC PC    + A  +GE CCLCG           +P IRS  R +  I GS  +DFC+  FC  C   Q+ ++
Sbjct:   22 FQTGLFECCDDCCTCMYGYFCLPCLGCSI-ASDMGE-CCLCGLG---------MP-IRSVYRTKYNIKGSMCKDFCISQFCLPCAACQLKRD 101

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 46.2098 bits (108), Expect = 3.385e-6
Identity = 33/106 (31.13%), Postives = 47/106 (44.34%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCL----CGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAI 371
            W  G+C C +D G+C   F+CP   +    K  GE  CL      F  + P   ++   +RS +R+R  I GS  +D CV   C  C   Q+ +E        Q I
Sbjct:   24 WSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYS---MRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKYRRQQPQVI 126

[Close]

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCL----CGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAI 371
            W  G+C C +D G+C   F+CP   +    K  GE  CL      F  + P   ++   +RS +R+R  I GS  +D CV   C  C   Q+ +E        Q I
Sbjct:   24 WSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYS---MRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKYRRQQPQVI 126

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009354.1 (pep scaffold:Pmarinus_7.0:GL483774:7229:14014:-1 gene:ENSPMAG00000008464.1 transcript:ENSPMAT00000009354.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 43.8986 bits (102), Expect = 2.500e-6
Identity = 31/105 (29.52%), Postives = 45/105 (42.86%), Query Frame = 3

Query:   57 EYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAI 371
            +  W   +  CF D  +C+  FFC        A   GE  C C    + P A+     +R+ IR+R  I G+  +DF     C  CTT QM +E     +   A+
Sbjct:   20 QAQWSSHMMDCFQDTEICVCGFFCLPLLQCKVASDFGE--CFC--VPMLPGALMA---LRTGIRERHHIEGTVFDDFVSLWCCNHCTTCQMARELRHQKNRGTAV 117

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Nematostella
Match: EDO50068 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFB0])

HSP 1 Score: 85.1149 bits (209), Expect = 1.452e-21
Identity = 42/105 (40.00%), Postives = 63/105 (60.00%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAA-IFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIER 377
            W +GL  CF+DCG CL+++  PCYT G +A+AVG+SC LCG A   P   +  +  +R  IR++  I GS++ D    + CP C+  Q  Q+  + +  SQ+I R
Sbjct:    5 WNNGLFGCFNDCGTCLITYIAPCYTFGKNAEAVGDSCLLCGLAFFVPVVDLIVMSSVRGKIREQHGISGSFIGDCAATICCPFCSLVQSAQQV-KGAPGSQSIAR 108

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Nematostella
Match: EDO44794 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUR8])

HSP 1 Score: 79.7221 bits (195), Expect = 1.817e-19
Identity = 41/105 (39.05%), Postives = 58/105 (55.24%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGF-ATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIER 377
            W  G+C CF+D   C +++FCPC   G +A+AVGE+C L GF +T+    IF    IR  IR++  I GS+  D  +  FCP C  +Q  +E        QA+ R
Sbjct:    3 WSSGICGCFEDINTCALTYFCPCVVAGKNAEAVGENCFLHGFLSTLGCVGIFCGAKIREKIREKHGIEGSFGNDCIMHWFCPLCAYSQEARELKARCPSGQAMAR 107

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Nematostella
Match: EDO36116 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJK5])

HSP 1 Score: 67.781 bits (164), Expect = 7.140e-15
Identity = 37/105 (35.24%), Postives = 56/105 (53.33%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITP-AAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIER 377
            + +GL  CF D  LCL ++  PCYT G  A+AVGE C +CG   + P A I+    IR  +R+++ I GS++ D  +   C  C+  Q   E    + +  +I R
Sbjct:    4 FSNGLFGCFSDIPLCLTTYCVPCYTFGKTAEAVGEDCLMCGIVLMVPCANIWFATQIRGKVREQKGIEGSFVNDLLMTWCCGFCSIIQEALEMGVKAPIGNSIAR 108

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Nematostella
Match: EDO42612 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0W1])

HSP 1 Score: 54.6842 bits (130), Expect = 9.279e-10
Identity = 28/97 (28.87%), Postives = 43/97 (44.33%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSS 356
            W  G+C CFDD G CL+ +FCPC+ +   ++ +GE                 +  +R  +R  Q I GS + D+C     P C   Q+ +E      
Sbjct:   54 WHSGMCGCFDDIGSCLLGYFCPCFLLIDVSQRMGEG------CCFPCCCPGALVGLRVKLRVEQNIQGSLINDYCAVQCLPLCVLCQLSRELKHLGR 144

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Nematostella
Match: EDO42647 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0V8])

HSP 1 Score: 45.4394 bits (106), Expect = 1.627e-6
Identity = 32/99 (32.32%), Postives = 42/99 (42.42%), Query Frame = 3

Query:   54 HEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGE----SCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
             +  W  GL  C  D G CLV+F CPC T+   ++ +GE     CC    A  T         +R+ +R  Q I GS   D      C  C   QM +E
Sbjct:   26 QQRDWSSGLFECTKDIGGCLVTFLCPCVTLCQISQRMGEGLAYGCCCADIAAFT---------LRAKLRTEQNIQGSLCNDAIHVSCCMHCALCQMSRE 115

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Medaka
Match: ponzr1 (cornifelin homolog B [Source:NCBI gene;Acc:110017082])

HSP 1 Score: 51.9878 bits (123), Expect = 2.366e-8
Identity = 34/103 (33.01%), Postives = 49/103 (47.57%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAI 371
            W  G+C C  D G C  + +C PC    M  +   +    C    +    + T  L+RS IR+R  IPGS ++D C  +FC  C   QMH+E    S+   A+
Sbjct:   40 WSTGMCECCADVGTCCCAMWCFPC----MQCQTAQKHGWCCAMPLLDICGVVTC-LLRSSIRERHHIPGSCIDDCCKCMFCYPCVWCQMHREVKVRSNAGSAV 137

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Medaka
Match: ENSORLT00000028572.1 (cornifelin homolog [Source:NCBI gene;Acc:101172524])

HSP 1 Score: 45.0542 bits (105), Expect = 4.729e-6
Identity = 29/99 (29.29%), Postives = 44/99 (44.44%), Query Frame = 3

Query:   42 DSDYHEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQE 338
             ++     W  GLCSCF+DC +C + FFCP       A   GE+ CL       P  +     +R+++R    I G+   D  +   C  C   +M +E
Sbjct:   16 GTNVQTGEWSTGLCSCFNDCLICALGFFCPAGLSCYTAHKYGENFCL----GCVPGGM---TAMRTHMRLTYGIQGTVCNDAIMVFCCGLCEMCRMARE 107

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Medaka
Match: ENSORLT00000040567.1 (pep primary_assembly:ASM223467v1:4:15638746:15640366:-1 gene:ENSORLG00000022609.1 transcript:ENSORLT00000040567.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 45.8246 bits (107), Expect = 5.182e-6
Identity = 42/145 (28.97%), Postives = 61/145 (42.07%), Query Frame = 3

Query:   12 NNKVL*DQMSDSDYHEYYWQHGLCSCFDDCGLCLVSFFC-PCYTVGMDAKAVGESCCL-------------CGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE*RAEIYIN 404
            N+ +  +QM+ +   E  W  GLC CF+D   C   F+C PC    +  K  GE  CL             CG     P   F+    RS +R+R  I GS  +D  V   C  C+  QMH+E        + I  +   + ++N
Sbjct:    3 NDVLFQNQMAQNALVE--WNTGLCDCFEDAATCCYGFWCGPCLACSVSGK-FGEFYCLPLCDYFCQSTLNACGIPCFVPPVAFST---RSSMRNRYGIKGSLCKDLVVSCCCVWCSWCQMHRELKHQKKAPEVIHMQ--PQTFVN 139

[Close]

BLAST of Cell number regulator 7 vs. Ensembl Medaka
Match: ponzr1 (cornifelin homolog B [Source:NCBI gene;Acc:110017082])

HSP 1 Score: 44.669 bits (104), Expect = 5.875e-6
Identity = 21/48 (43.75%), Postives = 29/48 (60.42%), Query Frame = 3

Query:  228 LIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAI 371
            L+RS IR+R  IPGS ++D C  +FC  C   QMH+E    S+   A+
Sbjct:   59 LLRSSIRERHHIPGSCIDDCCKCMFCYPCVWCQMHREVKVRSNAGSAV 106

[Close]

BLAST of Cell number regulator 7 vs. Planmine SMEST
Match: SMESG000060415.1 (SMESG000060415.1)

HSP 1 Score: 237.269 bits (604), Expect = 8.232e-81
Identity = 114/115 (99.13%), Postives = 115/115 (100.00%), Query Frame = 3

Query:   36 MSDSDYHEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 380
            MSDS+YHEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE
Sbjct:    1 MSDSEYHEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 115

[Close]

BLAST of Cell number regulator 7 vs. Planmine SMEST
Match: SMESG000060403.1 (SMESG000060403.1)

HSP 1 Score: 200.675 bits (509), Expect = 1.996e-66
Identity = 95/113 (84.07%), Postives = 104/113 (92.04%), Query Frame = 3

Query:   36 MSDSDYHEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIE 374
            MS+SDYH+Y WQHGLCSCFDDCGLCLV+FFCPCYTVG+DA+AVGE+CCLCGFA +TPAA FTVPLIRSYIRDRQKIPGSY EDFCVF +CPCCTTAQMHQETYEFS  S + E
Sbjct:    1 MSESDYHDYDWQHGLCSCFDDCGLCLVAFFCPCYTVGVDAEAVGENCCLCGFAVLTPAACFTVPLIRSYIRDRQKIPGSYCEDFCVFFWCPCCTTAQMHQETYEFSPHSMSRE 113

[Close]

BLAST of Cell number regulator 7 vs. Planmine SMEST
Match: SMESG000023846.1 (SMESG000023846.1)

HSP 1 Score: 105.145 bits (261), Expect = 5.844e-29
Identity = 47/105 (44.76%), Postives = 67/105 (63.81%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 380
            WQHGLC CF DCG CL+S+F PCY VG DA+AVG+SC LCG   +         ++R  +R+++ I G++  D     +CPCC+ AQ HQE    ++ + +IER+
Sbjct:    4 WQHGLCGCFSDCGTCLLSYFVPCYLVGKDAEAVGDSCFLCGLGYLVIYGCVG-AIVRKKVREKRGISGNFCFDLVASCWCPCCSVAQTHQEVLAMNAAAMSIERD 107

[Close]

BLAST of Cell number regulator 7 vs. Planmine SMEST
Match: SMESG000023831.1 (SMESG000023831.1)

HSP 1 Score: 95.1301 bits (235), Expect = 3.761e-25
Identity = 47/105 (44.76%), Postives = 62/105 (59.05%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 380
            WQ G+C CF D G C++++F PCY VG+DA+ V ++C LC  A +      T   IR  +R ++ IPG    D  V LF PCCT AQMH E    S  + A+ERE
Sbjct:    4 WQQGICGCFGDLGTCVLAYFAPCYLVGLDAETVDKNCVLCCIAFLFFPPCITCH-IRGKVRSKRNIPGGSCNDCVVSLFLPCCTVAQMHHEVKHMSGTAMALERE 107

[Close]

BLAST of Cell number regulator 7 vs. Planmine SMEST
Match: SMESG000023842.1 (SMESG000023842.1)

HSP 1 Score: 88.5817 bits (218), Expect = 1.427e-22
Identity = 52/105 (49.52%), Postives = 67/105 (63.81%), Query Frame = 3

Query:   66 WQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLCGFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQETYEFSSMSQAIERE 380
            W+HGLC C DDCG CL+++F PCY +G DA+AVG+SC LCG  ++  A    +  +RS +RDR+ I GS++ D      C CC  AQMHQE       S AIERE
Sbjct:    4 WEHGLCGCCDDCGTCLLTYFVPCYLIGKDAEAVGDSCFLCGCGSLF-AGPCIIAYVRSKVRDRRNITGSFIGDLLCAFCCGCCVVAQMHQEVIAMGGSSMAIERE 107

The following BLAST results are available for this feature:

BLAST of Cell number regulator 7 vs. Ensembl Human
BLAST of Cell number regulator 7 vs. Ensembl Celegans
BLAST of Cell number regulator 7 vs. Ensembl Fly
BLAST of Cell number regulator 7 vs. Ensembl Zebrafish
BLAST of Cell number regulator 7 vs. Ensembl Xenopus
BLAST of Cell number regulator 7 vs. Ensembl Mouse
BLAST of Cell number regulator 7 vs. UniProt/SwissProt
BLAST of Cell number regulator 7 vs. TrEMBL
BLAST of Cell number regulator 7 vs. Ensembl Cavefish
BLAST of Cell number regulator 7 vs. Ensembl Sea Lamprey
BLAST of Cell number regulator 7 vs. Ensembl Yeast
BLAST of Cell number regulator 7 vs. Ensembl Nematostella
BLAST of Cell number regulator 7 vs. Ensembl Medaka
BLAST of Cell number regulator 7 vs. Planmine SMEST

BLAST of Cell number regulator 7 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4


Match Name	E-value	Identity	Description
PLAC8	1.594e-11	36.89	placenta associated 8 [Source:HGNC Symbol;Acc:HGNC...	[more]
PLAC8	1.594e-11	36.89	placenta associated 8 [Source:HGNC Symbol;Acc:HGNC...	[more]
PLAC8	1.594e-11	36.89	placenta associated 8 [Source:HGNC Symbol;Acc:HGNC...	[more]
PLAC8	1.594e-11	36.89	placenta associated 8 [Source:HGNC Symbol;Acc:HGNC...	[more]

BLAST of Cell number regulator 7 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Cell number regulator 7 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Cell number regulator 7 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ponzr10	3.463e-6	32.74	plac8 onzin related protein 10 [Source:ZFIN;Acc:ZD...	[more]
BX005027.2	3.545e-6	32.74	plac8 onzin related protein 10 [Source:NCBI gene;A...	[more]

BLAST of Cell number regulator 7 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
paqr6	2.070e-7	35.16	progestin and adipoQ receptor family member VI [So...	[more]
eps15l1	2.070e-7	35.16	epidermal growth factor receptor pathway substrate...	[more]
paqr6	2.311e-7	35.16	progestin and adipoQ receptor family member VI [So...	[more]
eps15l1	2.455e-7	35.16	epidermal growth factor receptor pathway substrate...	[more]
abtb1	5.056e-7	32.63	ankyrin repeat and BTB (POZ) domain containing 1 [...	[more]

BLAST of Cell number regulator 7 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Plac8	7.058e-13	36.54	placenta-specific 8 [Source:MGI Symbol;Acc:MGI:244...	[more]
Plac8	7.058e-13	36.54	placenta-specific 8 [Source:MGI Symbol;Acc:MGI:244...	[more]
Plac8	7.058e-13	36.54	placenta-specific 8 [Source:MGI Symbol;Acc:MGI:244...	[more]

BLAST of Cell number regulator 7 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9JI48\|PLAC8_MOUSE	4.937e-12	36.54	Placenta-specific gene 8 protein OS=Mus musculus O...	[more]
sp\|Q9NZF1\|PLAC8_HUMAN	7.654e-11	36.89	Placenta-specific gene 8 protein OS=Homo sapiens O...	[more]
sp\|Q5REK4\|PLAC8_PONAB	3.443e-10	35.92	Placenta-specific gene 8 protein OS=Pongo abelii O...	[more]
sp\|Q3ZCB2\|PLAC8_BOVIN	9.513e-9	37.89	Placenta-specific gene 8 protein OS=Bos taurus OX=...	[more]
sp\|Q6DK99\|CNFNB_XENLA	2.258e-6	33.68	Cornifelin homolog B OS=Xenopus laevis OX=8355 GN=...	[more]

BLAST of Cell number regulator 7 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267H0G2	1.279e-30	51.43	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8JKZ3	1.456e-30	51.43	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267EXF1	2.173e-30	50.48	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8HVT9	1.163e-29	48.57	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267GVB5	7.068e-29	49.52	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]

BLAST of Cell number regulator 7 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ponzr6	1.352e-6	31.13	cornifelin homolog [Source:NCBI gene;Acc:103028345...	[more]
plac8.1	2.290e-6	36.08	placenta associated 8 [Source:NCBI gene;Acc:103039...	[more]
plac8.1	2.607e-6	38.04	placenta associated 8 [Source:NCBI gene;Acc:103039...	[more]
ponzr6	3.385e-6	31.13	cornifelin homolog [Source:NCBI gene;Acc:103028345...	[more]
ponzr6	3.385e-6	31.13	cornifelin homolog [Source:NCBI gene;Acc:103028345...	[more]

BLAST of Cell number regulator 7 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000009354.1	2.500e-6	29.52	pep scaffold:Pmarinus_7.0:GL483774:7229:14014:-1 g...	[more]

BLAST of Cell number regulator 7 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Cell number regulator 7 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO50068	1.452e-21	40.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44794	1.817e-19	39.05	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36116	7.140e-15	35.24	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42612	9.279e-10	28.87	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42647	1.627e-6	32.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Cell number regulator 7 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ponzr1	2.366e-8	33.01	cornifelin homolog B [Source:NCBI gene;Acc:1100170...	[more]
ENSORLT00000028572.1	4.729e-6	29.29	cornifelin homolog [Source:NCBI gene;Acc:101172524...	[more]
ENSORLT00000040567.1	5.182e-6	28.97	pep primary_assembly:ASM223467v1:4:15638746:156403...	[more]
ponzr1	5.875e-6	43.75	cornifelin homolog B [Source:NCBI gene;Acc:1100170...	[more]

BLAST of Cell number regulator 7 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000060415.1	8.232e-81	99.13	SMESG000060415.1	[more]
SMESG000060403.1	1.996e-66	84.07	SMESG000060403.1	[more]
SMESG000023846.1	5.844e-29	44.76	SMESG000023846.1	[more]
SMESG000023831.1	3.761e-25	44.76	SMESG000023831.1	[more]
SMESG000023842.1	1.427e-22	49.52	SMESG000023842.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30005770 ID=SMED30005770|Name=Cell number regulator 7|organism=Schmidtea mediterranea sexual|type=transcript|length=670bp
TTTTTTTCAGGAATAATAAAGTTTTATAAGATCAAATGTCTGACTCGGAT
TATCACGAATATTATTGGCAACATGGACTATGCAGTTGTTTTGATGATTG
CGGTTTATGTTTAGTATCATTTTTTTGTCCATGCTACACAGTTGGAATGG
ACGCCAAGGCTGTGGGAGAAAGTTGTTGTCTCTGTGGATTTGCTACAATT
ACACCTGCTGCGATTTTTACAGTTCCACTTATTAGAAGTTATATTCGAGA
CCGACAAAAAATTCCCGGAAGTTATTTAGAAGATTTTTGTGTGTTTCTAT
TTTGTCCATGCTGTACTACTGCTCAGATGCATCAAGAAACTTATGAGTTT
AGTTCAATGTCTCAAGCCATTGAACGAGAGTAAAGAGCCGAAATATATAT
AAATTCTAGATCAGTCTCTTCAGTGGTGATATAAACAAATTTTTCCTCAA
ACCCGTTTTGATTTTAAACATTATAATTGTTTTTGGTACAGCTTTTAAAA
TTTACAATCACTACAGTAAAACAATAAAATGAAATTGTTGTCAGTGTTTA
ATAGATATTATGCAGATATGTGCCTGTATTAGGTTCAGTTATGTAACTTT
AATGGTAATGGAATTGATCTTTGAACTCGAATTAATAAATAAAGTTCAAT
CTATTTTCTTTAAAAAAAAA

protein sequence of SMED30005770-orf-1

>SMED30005770-orf-1 ID=SMED30005770-orf-1|Name=SMED30005770-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=116bp
MSDSDYHEYYWQHGLCSCFDDCGLCLVSFFCPCYTVGMDAKAVGESCCLC
GFATITPAAIFTVPLIRSYIRDRQKIPGSYLEDFCVFLFCPCCTTAQMHQ
ETYEFSSMSQAIERE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000020	protonephridia
PLANA:0000026	gut
PLANA:0000070	intestinal phagocyte
PLANA:0003116	parenchymal cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR006461	PLAC_motif_containing

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006461	PLAC8 motif-containing protein	PFAM	PF04749	PLAC8	coord: 11..101 e-value: 3.1E-19 score: 69.8
IPR006461	PLAC8 motif-containing protein	TIGRFAM	TIGR01571	TIGR01571	coord: 11..101 e-value: 5.4E-20 score: 70.1
IPR006461	PLAC8 motif-containing protein	PANTHER	PTHR15907	FAMILY NOT NAMED	coord: 10..112
None	No IPR available	PANTHER	PTHR15907:SF102		coord: 10..112

Main menu

Cell number regulator 7

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Owlery

blazegraph-runner