Zinc knuckle-domain-containing protein

Overview
NameZinc knuckle-domain-containing protein
Smed IDSMED30005755
Length (bp)497
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Zinc knuckle-domain-containing protein (SMED30005755) t-SNE clustered cells

Violin plots show distribution of expression levels for Zinc knuckle-domain-containing protein (SMED30005755) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Zinc knuckle-domain-containing protein (SMED30005755) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Zinc knuckle-domain-containing protein (SMED30005755) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005755

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30005755SMESG000050169.1 SmedASXL_000560SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Human
Match: ZCCHC10 (zinc finger CCHC-type containing 10 [Source:HGNC Symbol;Acc:HGNC:25954])

HSP 1 Score: 51.6026 bits (122), Expect = 1.666e-8
Identity = 23/53 (43.40%), Postives = 35/53 (66.04%), Query Frame = 3 
Query:   81 PSFLAKKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQET 239
            PS +  +  +   +CQKCLE GHWT+EC  KR +L+R ++  ELK+  K++E 
Sbjct:   31 PSIVISEANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKEN 83
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Human
Match: ZCCHC10 (zinc finger CCHC-type containing 10 [Source:HGNC Symbol;Acc:HGNC:25954])

HSP 1 Score: 51.9878 bits (123), Expect = 3.211e-8
Identity = 23/52 (44.23%), Postives = 35/52 (67.31%), Query Frame = 3 
Query:   81 PSFLAKKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQE 236
            PS +  +  +   +CQKCLE GHWT+EC  KR +L+R ++  ELK+  K++E
Sbjct:   31 PSIVISEANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKE 82
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Human
Match: ZCCHC10 (zinc finger CCHC-type containing 10 [Source:HGNC Symbol;Acc:HGNC:25954])

HSP 1 Score: 51.9878 bits (123), Expect = 3.555e-8
Identity = 23/52 (44.23%), Postives = 35/52 (67.31%), Query Frame = 3 
Query:   81 PSFLAKKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQE 236
            PS +  +  +   +CQKCLE GHWT+EC  KR +L+R ++  ELK+  K++E
Sbjct:   31 PSIVISEANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKE 82
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Human
Match: ZCCHC10 (zinc finger CCHC-type containing 10 [Source:HGNC Symbol;Acc:HGNC:25954])

HSP 1 Score: 48.521 bits (114), Expect = 1.492e-7
Identity = 21/40 (52.50%), Postives = 30/40 (75.00%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQET 239
            +CQKCLE GHWT+EC  KR +L+R ++  ELK+  K++E 
Sbjct:   22 RCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKEN 61
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Human
Match: ZCCHC10 (zinc finger CCHC-type containing 10 [Source:HGNC Symbol;Acc:HGNC:25954])

HSP 1 Score: 49.2914 bits (116), Expect = 2.346e-7
Identity = 21/39 (53.85%), Postives = 30/39 (76.92%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQE 236
            +CQKCLE GHWT+EC  KR +L+R ++  ELK+  K++E
Sbjct:   22 RCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKE 60
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Fly
Match: CG5516 (gene:FBgn0038389 transcript:FBtr0083212)

HSP 1 Score: 47.7506 bits (112), Expect = 5.400e-7
Identity = 18/43 (41.86%), Postives = 31/43 (72.09%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDEL-KELEKKQETVP 245
            +CQKCL+ GHW++ECK KR +++R ++  +L K + +K+   P
Sbjct:   29 RCQKCLQIGHWSYECKEKRKYVHRSSRTKQLSKRMSQKEADAP 71
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Fly
Match: CG5516 (gene:FBgn0038389 transcript:FBtr0302549)

HSP 1 Score: 47.7506 bits (112), Expect = 5.400e-7
Identity = 18/43 (41.86%), Postives = 31/43 (72.09%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDEL-KELEKKQETVP 245
            +CQKCL+ GHW++ECK KR +++R ++  +L K + +K+   P
Sbjct:   29 RCQKCLQIGHWSYECKEKRKYVHRSSRTKQLSKRMSQKEADAP 71
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Zebrafish
Match: zcchc10 (zinc finger, CCHC domain containing 10 [Source:ZFIN;Acc:ZDB-GENE-030131-6172])

HSP 1 Score: 48.1358 bits (113), Expect = 4.249e-7
Identity = 20/43 (46.51%), Postives = 30/43 (69.77%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQETVPA 248
            +CQKCLE GHW++EC  KR +L R ++  E+K+  K +E  P+
Sbjct:   22 RCQKCLEFGHWSYECTGKRKYLYRPSRTAEMKKKLKDKENNPS 64
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Xenopus
Match: unc13c (unc-13 homolog C [Source:Xenbase;Acc:XB-GENE-6044557])

HSP 1 Score: 51.6026 bits (122), Expect = 6.928e-8
Identity = 24/64 (37.50%), Postives = 38/64 (59.38%), Query Frame = 3 
Query:   57 VFENIRKLPSFLAKKDEESIS---KCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQET 239
            +F+    +   +A++  E+     +CQKCLE GHW++EC  KR +L R T+  ELK   K++E 
Sbjct:   40 LFDMATPMHRLIARRQAEANKQNVRCQKCLEMGHWSYECTGKRKYLYRPTRTTELKRALKEKEA 103
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Mouse
Match: Zcchc10 (zinc finger, CCHC domain containing 10 [Source:MGI Symbol;Acc:MGI:1196228])

HSP 1 Score: 50.8322 bits (120), Expect = 5.229e-8
Identity = 22/40 (55.00%), Postives = 31/40 (77.50%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQET 239
            +CQKCLE GHWT+ECK KR +L+R ++  ELK+  K++E 
Sbjct:   22 RCQKCLEFGHWTYECKGKRKYLHRPSRTAELKKALKEKEN 61
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8TBK6|ZCH10_HUMAN (Zinc finger CCHC domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZCCHC10 PE=1 SV=1)

HSP 1 Score: 51.9878 bits (123), Expect = 1.542e-7
Identity = 23/52 (44.23%), Postives = 35/52 (67.31%), Query Frame = 3 
Query:   81 PSFLAKKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQE 236
            PS +  +  +   +CQKCLE GHWT+EC  KR +L+R ++  ELK+  K++E
Sbjct:   31 PSIVISEANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKE 82
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9CX48|ZCH10_MOUSE (Zinc finger CCHC domain-containing protein 10 OS=Mus musculus OX=10090 GN=Zcchc10 PE=2 SV=1)

HSP 1 Score: 50.8322 bits (120), Expect = 3.658e-7
Identity = 22/40 (55.00%), Postives = 31/40 (77.50%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQET 239
            +CQKCLE GHWT+ECK KR +L+R ++  ELK+  K++E 
Sbjct:   22 RCQKCLEFGHWTYECKGKRKYLHRPSRTAELKKALKEKEN 61
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5EB97|ZCH10_RAT (Zinc finger CCHC domain-containing protein 10 OS=Rattus norvegicus OX=10116 GN=Zcchc10 PE=2 SV=2)

HSP 1 Score: 50.8322 bits (120), Expect = 3.996e-7
Identity = 22/40 (55.00%), Postives = 31/40 (77.50%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQET 239
            +CQKCLE GHWT+ECK KR +L+R ++  ELK+  K++E 
Sbjct:   22 RCQKCLEFGHWTYECKGKRKYLHRPSRTAELKKALKEKEN 61
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. TrEMBL
Match: A0A2R7WL34 (Uncharacterized protein OS=Oncopeltus fasciatus OX=7536 GN=OFAS_OFAS009228 PE=4 SV=1)

HSP 1 Score: 55.4546 bits (132), Expect = 2.287e-7
Identity = 27/56 (48.21%), Postives = 35/56 (62.50%), Query Frame = 3 
Query:   96 KKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKCDE----LKELEKKQETVPAV 251
            K  +   +KCQKCLE GHWT+ECK KR FLNR ++  +    LK +E+KQ    A 
Sbjct:   12 KSSQPQTAKCQKCLEVGHWTYECKGKRKFLNRSSRTAQLNKRLKLIEEKQNGTAAT 67
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. TrEMBL
Match: A0A023F769 (Putative zinc finger cchc domain-containing protein 10 OS=Triatoma infestans OX=30076 PE=2 SV=1)

HSP 1 Score: 56.225 bits (134), Expect = 3.647e-7
Identity = 25/47 (53.19%), Postives = 33/47 (70.21%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCD----ELKELEKKQETVPA 248
            KCQKCLE+GHWT+ECK KR FLNR ++       +K LE K++ +P 
Sbjct:   20 KCQKCLESGHWTYECKGKRKFLNRSSRSSLLNKRMKALEDKEKDIPP 66
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. TrEMBL
Match: A0A067R1R1 (Zinc finger CCHC domain-containing protein 10 OS=Zootermopsis nevadensis OX=136037 GN=L798_09284 PE=4 SV=1)

HSP 1 Score: 53.9138 bits (128), Expect = 8.223e-7
Identity = 27/56 (48.21%), Postives = 39/56 (69.64%), Query Frame = 3 
Query:   84 SFLAKKDE--ESISKCQKCLETGHWTFECKNKRVFLNRKTKCDELKE-LEKKQETV 242
              LAKK+      ++CQKCLE GHWTFECK KR +L+R ++  +LK+ L+ ++E V
Sbjct:    7 GMLAKKNSYPPQGARCQKCLEYGHWTFECKGKRKYLHRSSRTSQLKKRLKLREEAV 62
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. TrEMBL
Match: A0A151WN89 (Zinc finger CCHC domain-containing protein 10 (Fragment) OS=Trachymyrmex zeteki OX=64791 GN=ALC60_11615 PE=4 SV=1)

HSP 1 Score: 53.1434 bits (126), Expect = 1.312e-6
Identity = 21/40 (52.50%), Postives = 31/40 (77.50%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQET 239
            +CQKCLE GHW++ECK KR +L+R ++  +LK+  +KQE 
Sbjct:    8 RCQKCLEMGHWSYECKGKRKYLHRSSRTSQLKKAMQKQEN 47
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. TrEMBL
Match: A0A3B6RL00 (Uncharacterized protein OS=Triticum aestivum OX=4565 PE=4 SV=1)

HSP 1 Score: 56.9954 bits (136), Expect = 1.593e-6
Identity = 21/44 (47.73%), Postives = 34/44 (77.27%), Query Frame = 3 
Query:  117 SKCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQETVPA 248
             +CQKC + GHWT+ECKN+RV+++R ++ D+LK+   K+  +PA
Sbjct:   89 GQCQKCFQPGHWTYECKNERVYISRPSRTDQLKDPRLKKAWLPA 132
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000052589.1 (zinc finger CCHC-type containing 10 [Source:NCBI gene;Acc:103022142])

HSP 1 Score: 50.0618 bits (118), Expect = 7.539e-8
Identity = 22/45 (48.89%), Postives = 30/45 (66.67%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDE----LKELEKKQETV 242
            +CQKCLE GHW++EC  KR +L R ++  E    LKE+E K  +V
Sbjct:   22 RCQKCLEYGHWSYECTGKRKYLYRPSRTSEMKKKLKEMENKDPSV 66
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008415.1 (pep scaffold:Pmarinus_7.0:GL476642:71986:80050:-1 gene:ENSPMAG00000007613.1 transcript:ENSPMAT00000008415.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.595 bits (109), Expect = 2.578e-7
Identity = 25/63 (39.68%), Postives = 36/63 (57.14%), Query Frame = 3 
Query:   54 MVFENIRKLPSFLAKKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKCD----ELKELEKK 230
            M     R L    A  D+E++ +CQKCLE GHWT+EC + R +  R T+      +LKEL ++
Sbjct:    1 MATPMHRLLARRKADADKETV-RCQKCLELGHWTYECSSTRAYKQRPTRTALLQRQLKELTQR 62
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Nematostella
Match: EDO28323 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6T1])

HSP 1 Score: 45.8246 bits (107), Expect = 1.038e-7
Identity = 18/32 (56.25%), Postives = 24/32 (75.00%), Query Frame = 3 
Query:  105 EESISKCQKCLETGHWTFECKNKRVFLNRKTK 200
            E    KCQKCL+ GHWT+EC NKR +L+R ++
Sbjct:    1 EAGKQKCQKCLQIGHWTYECTNKRKYLHRMSR 32
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000001697.2 (zinc finger CCHC-type containing 10 [Source:NCBI gene;Acc:101167387])

HSP 1 Score: 47.7506 bits (112), Expect = 4.612e-7
Identity = 20/42 (47.62%), Postives = 30/42 (71.43%), Query Frame = 3 
Query:  120 KCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQETVP 245
            +CQKCLE GHWT+EC  KR +++R ++  E+K+  K+ E  P
Sbjct:   22 RCQKCLELGHWTYECTGKRKYVHRPSRTVEMKKKLKEVENKP 63
[Close]
BLAST of Zinc knuckle-domain-containing protein vs. Planmine SMEST
Match: SMESG000050169.1 (SMESG000050169.1)

HSP 1 Score: 155.221 bits (391), Expect = 4.203e-49
Identity = 135/138 (97.83%), Postives = 137/138 (99.28%), Query Frame = 3 
Query:   54 MVFENIRKLPSFLAKKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQETVPAVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPTVPKKKLKISENK 467
            MVFENIRKLPSFLAKKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQETVPAVDEYAEDSD+LSSDDSSSTSSSNDSSKSNSNAASSSDSDTSSSSDSDTSSSSDSSSSE+P VPKKKLKISENK
Sbjct:    1 MVFENIRKLPSFLAKKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKCDELKELEKKQETVPAVDEYAEDSDTLSSDDSSSTSSSNDSSKSNSNAASSSDSDTSSSSDSDTSSSSDSSSSETPIVPKKKLKISENK 138
The following BLAST results are available for this feature:
BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ZCCHC101.666e-843.40zinc finger CCHC-type containing 10 [Source:HGNC S... [more]
ZCCHC103.211e-844.23zinc finger CCHC-type containing 10 [Source:HGNC S... [more]
ZCCHC103.555e-844.23zinc finger CCHC-type containing 10 [Source:HGNC S... [more]
ZCCHC101.492e-752.50zinc finger CCHC-type containing 10 [Source:HGNC S... [more]
ZCCHC102.346e-753.85zinc finger CCHC-type containing 10 [Source:HGNC S... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG55165.400e-741.86gene:FBgn0038389 transcript:FBtr0083212[more]
CG55165.400e-741.86gene:FBgn0038389 transcript:FBtr0302549[more]
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
zcchc104.249e-746.51zinc finger, CCHC domain containing 10 [Source:ZFI... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
unc13c6.928e-837.50unc-13 homolog C [Source:Xenbase;Acc:XB-GENE-60445... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Zcchc105.229e-855.00zinc finger, CCHC domain containing 10 [Source:MGI... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|Q8TBK6|ZCH10_HUMAN1.542e-744.23Zinc finger CCHC domain-containing protein 10 OS=H... [more]
sp|Q9CX48|ZCH10_MOUSE3.658e-755.00Zinc finger CCHC domain-containing protein 10 OS=M... [more]
sp|Q5EB97|ZCH10_RAT3.996e-755.00Zinc finger CCHC domain-containing protein 10 OS=R... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2R7WL342.287e-748.21Uncharacterized protein OS=Oncopeltus fasciatus OX... [more]
A0A023F7693.647e-753.19Putative zinc finger cchc domain-containing protei... [more]
A0A067R1R18.223e-748.21Zinc finger CCHC domain-containing protein 10 OS=Z... [more]
A0A151WN891.312e-652.50Zinc finger CCHC domain-containing protein 10 (Fra... [more]
A0A3B6RL001.593e-647.73Uncharacterized protein OS=Triticum aestivum OX=45... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSAMXT00000052589.17.539e-848.89zinc finger CCHC-type containing 10 [Source:NCBI g... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000008415.12.578e-739.68pep scaffold:Pmarinus_7.0:GL476642:71986:80050:-1 ... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO283231.038e-756.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSORLT00000001697.24.612e-747.62zinc finger CCHC-type containing 10 [Source:NCBI g... [more]
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BLAST of Zinc knuckle-domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000050169.14.203e-4997.83SMESG000050169.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005755 ID=SMED30005755|Name=Zinc knuckle-domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=497bp
CTAAATTCGATAGCATCGATTTGTTTAAATAATCTCTATCATTTAAAATA
TAAATGGTTTTCGAAAATATAAGAAAGTTGCCATCATTTTTGGCAAAAAA
AGATGAAGAATCTATTTCCAAATGTCAGAAGTGCTTGGAAACCGGTCATT
GGACCTTTGAATGTAAAAACAAAAGAGTATTTCTAAATAGAAAAACTAAA
TGTGATGAATTAAAAGAACTTGAAAAAAAGCAAGAAACTGTACCAGCTGT
CGATGAATATGCAGAAGATTCTGATAGCTTGTCTTCTGACGATAGTAGTT
CTACTTCTAGCAGTAATGATAGTTCCAAATCAAATTCTAATGCAGCCAGT
TCTTCAGATTCTGATACATCCAGTTCATCAGATTCTGATACATCAAGTTC
TTCAGATTCATCAAGTTCAGAATCTCCAACAGTTCCAAAAAAGAAACTTA
AAATATCAGAAAATAAATAATTTTATATTTTTAATAGATTAATTTTG
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protein sequence of SMED30005755-orf-1

>SMED30005755-orf-1 ID=SMED30005755-orf-1|Name=SMED30005755-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=139bp
MVFENIRKLPSFLAKKDEESISKCQKCLETGHWTFECKNKRVFLNRKTKC
DELKELEKKQETVPAVDEYAEDSDSLSSDDSSSTSSSNDSSKSNSNAASS
SDSDTSSSSDSDTSSSSDSSSSESPTVPKKKLKISENK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR036875Znf_CCHC_sf
IPR001878Znf_CCHC
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePFAMPF13917zf-CCHC_3coord: 24..49
e-value: 4.2E-10
score: 39.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 76..126
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 58..138
IPR036875Zinc finger, CCHC-type superfamilySUPERFAMILYSSF57756Retrovirus zinc finger-like domainscoord: 18..52