Protein kinase

Overview
NameProtein kinase
Smed IDSMED30005745
Length (bp)775
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein kinase (SMED30005745) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase (SMED30005745) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase (SMED30005745) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase (SMED30005745) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005745

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 18

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30005745h1SMcG0020711 Contig2289GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30005745h1SMcG0020711 Contig2289GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30005745h1SMcG0020711 Contig2289GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
cephalic gangliaSMED30005745h1SMcG0020711 dd_Smed_v4_4170_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30005745h1SMcG0020711 dd_Smed_v4_4170_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30005745h1SMcG0020711 dd_Smed_v4_4322_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30005745h1SMcG0020711 dd_Smed_v4_4322_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30005745h1SMcG0020711 dd_Smed_v4_4322_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30005745h1SMcG0020711 dd_Smed_v4_4322_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005745h1SMcG0020711 Contig34002uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005745h1SMcG0020711 Contig34002newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005745h1SMcG0020712 Contig34002uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005745h1SMcG0020712 Contig34002newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005745h1SMcG0020713 Contig34002uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005745h1SMcG0020713 Contig34002newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30005745h1SMcG0020711 dd_Smed_v4_4170_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Category 4 cellSMED30005745h1SMcG0020711 dd_Smed_v4_4170_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30005745h1SMcG0020711 dd_Smed_v4_4322_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404])

HSP 1 Score: 91.2781 bits (225), Expect = 4.047e-22
Identity = 54/136 (39.71%), Postives = 76/136 (55.88%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSE 398
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  V+  +N+D   RPTA++L+  +
Sbjct:   43 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHK 174
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404])

HSP 1 Score: 92.0485 bits (227), Expect = 1.153e-21
Identity = 54/133 (40.60%), Postives = 75/133 (56.39%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+   L      TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:   19 IHRDIKAANVLLSEQGDVKLADFGVAGQLTD----TQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELL 147
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404])

HSP 1 Score: 91.6633 bits (226), Expect = 5.358e-21
Identity = 53/132 (40.15%), Postives = 74/132 (56.06%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+   L    D      TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:   43 IHRDIKAANVLLSEQGDVKLADFGVAGQL---TDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELL 171
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404])

HSP 1 Score: 91.6633 bits (226), Expect = 5.358e-21
Identity = 53/132 (40.15%), Postives = 74/132 (56.06%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+   L    D      TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:   43 IHRDIKAANVLLSEQGDVKLADFGVAGQL---TDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELL 171
[Close]
BLAST of Protein kinase vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404])

HSP 1 Score: 91.6633 bits (226), Expect = 5.951e-21
Identity = 53/132 (40.15%), Postives = 74/132 (56.06%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+   L    D      TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:   60 IHRDIKAANVLLSEQGDVKLADFGVAGQL---TDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELL 188
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: aak-2 (5'-AMP-activated protein kinase catalytic subunit alpha-2 [Source:UniProtKB/Swiss-Prot;Acc:Q95ZQ4])

HSP 1 Score: 88.5817 bits (218), Expect = 9.022e-20
Identity = 49/138 (35.51%), Postives = 79/138 (57.25%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFP-ADIYSLGVTIYNMMTGNIP---SCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            +HRD+KP N+L+D+ NNVK+ADFGL  ++   +    F  T CGSP++ APE+   K Y+ P  D++S GV +Y ++ G +P        + +KIK    PT  +   +   N++ +M+  D  KR T + ++  E F
Sbjct:  145 VHRDLKPENLLLDEQNNVKIADFGLSNIMTDGD----FLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPT-PDFLERPIVNLLHHMLCVDPMKRATIKDVIAHEWF 277
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: aak-2 (5'-AMP-activated protein kinase catalytic subunit alpha-2 [Source:UniProtKB/Swiss-Prot;Acc:Q95ZQ4])

HSP 1 Score: 88.5817 bits (218), Expect = 9.022e-20
Identity = 49/138 (35.51%), Postives = 79/138 (57.25%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFP-ADIYSLGVTIYNMMTGNIP---SCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            +HRD+KP N+L+D+ NNVK+ADFGL  ++   +    F  T CGSP++ APE+   K Y+ P  D++S GV +Y ++ G +P        + +KIK    PT  +   +   N++ +M+  D  KR T + ++  E F
Sbjct:  145 VHRDLKPENLLLDEQNNVKIADFGLSNIMTDGD----FLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPT-PDFLERPIVNLLHHMLCVDPMKRATIKDVIAHEWF 277
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: aak-2 (5'-AMP-activated protein kinase catalytic subunit alpha-2 [Source:UniProtKB/Swiss-Prot;Acc:Q95ZQ4])

HSP 1 Score: 88.1965 bits (217), Expect = 1.121e-19
Identity = 50/138 (36.23%), Postives = 79/138 (57.25%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFP-ADIYSLGVTIYNMMTGNIP---SCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            +HRD+KP N+L+D+ NNVK+ADFGL  ++   +    F  T CGSP++ APE+   K Y+ P  D++S GV +Y ++ G +P        + +KIK    PT    +R    N++ +M+  D  KR T + ++  E F
Sbjct:  207 VHRDLKPENLLLDEQNNVKIADFGLSNIMTDGD----FLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERP-IVNLLHHMLCVDPMKRATIKDVIAHEWF 339
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: aak-2 (5'-AMP-activated protein kinase catalytic subunit alpha-2 [Source:UniProtKB/Swiss-Prot;Acc:Q95ZQ4])

HSP 1 Score: 88.1965 bits (217), Expect = 1.166e-19
Identity = 50/138 (36.23%), Postives = 79/138 (57.25%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFP-ADIYSLGVTIYNMMTGNIP---SCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            +HRD+KP N+L+D+ NNVK+ADFGL  ++   +    F  T CGSP++ APE+   K Y+ P  D++S GV +Y ++ G +P        + +KIK    PT    +R    N++ +M+  D  KR T + ++  E F
Sbjct:  207 VHRDLKPENLLLDEQNNVKIADFGLSNIMTDGD----FLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERP-IVNLLHHMLCVDPMKRATIKDVIAHEWF 339
[Close]
BLAST of Protein kinase vs. Ensembl Celegans
Match: gck-3 (Germinal center kinase 3 [Source:UniProtKB/Swiss-Prot;Acc:G5EEN4])

HSP 1 Score: 87.4261 bits (215), Expect = 1.645e-19
Identity = 50/150 (33.33%), Postives = 82/150 (54.67%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLM---GPNDRTQFAMTFCGSPSFMAPEINKN-KPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFD---PTL-SESKRKE--------FENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRDIK  N+L+  D  +++ADFG+   L    G   R +   TF G+P +MAPE+ +  + Y F ADI+SLG+    + TG  P      +K + +      PTL + ++RK+        F+ ++++ + +D +KRPTA +L+    F
Sbjct:   80 IHRDIKAGNILLADDGTIQIADFGVSGWLASSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFF 229
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399)

HSP 1 Score: 89.7373 bits (221), Expect = 4.846e-20
Identity = 50/132 (37.88%), Postives = 75/132 (56.82%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            +HRDIK ANVL+ +  +VKLADFG+   L     +     TF G+P +MAPE+ K   Y   ADI+SLG+T   +  G  P+       ++  I  +  P L+ S  K F++ V+  +N+D   RPTA++L+
Sbjct:  130 LHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRN---TFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPQLTGSYTKSFKDFVEACLNKDPENRPTAKELL 258
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: fray (gene:FBgn0023083 transcript:FBtr0083638)

HSP 1 Score: 88.1965 bits (217), Expect = 1.292e-19
Identity = 51/149 (34.23%), Postives = 76/149 (51.01%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPND--RTQFAMTFCGSPSFMAPEI-NKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFD---PTLS---------ESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRDIK  N+LI  D  +++ADFG+   L    D  R +   TF G+P +MAPE+  ++  Y F ADI+S G+T   M TG  P      +K + +      PTL          ++  K F  ++   + ++ SKRPTA +L+    F
Sbjct:  164 IHRDIKAGNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFF 312
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: fray (gene:FBgn0023083 transcript:FBtr0347418)

HSP 1 Score: 88.1965 bits (217), Expect = 1.292e-19
Identity = 51/149 (34.23%), Postives = 76/149 (51.01%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPND--RTQFAMTFCGSPSFMAPEI-NKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFD---PTLS---------ESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRDIK  N+LI  D  +++ADFG+   L    D  R +   TF G+P +MAPE+  ++  Y F ADI+S G+T   M TG  P      +K + +      PTL          ++  K F  ++   + ++ SKRPTA +L+    F
Sbjct:  164 IHRDIKAGNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFF 312
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: fray (gene:FBgn0023083 transcript:FBtr0290210)

HSP 1 Score: 88.1965 bits (217), Expect = 1.292e-19
Identity = 51/149 (34.23%), Postives = 76/149 (51.01%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPND--RTQFAMTFCGSPSFMAPEI-NKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFD---PTLS---------ESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRDIK  N+LI  D  +++ADFG+   L    D  R +   TF G+P +MAPE+  ++  Y F ADI+S G+T   M TG  P      +K + +      PTL          ++  K F  ++   + ++ SKRPTA +L+    F
Sbjct:  164 IHRDIKAGNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFF 312
[Close]
BLAST of Protein kinase vs. Ensembl Fly
Match: fray (gene:FBgn0023083 transcript:FBtr0290107)

HSP 1 Score: 88.1965 bits (217), Expect = 1.292e-19
Identity = 51/149 (34.23%), Postives = 76/149 (51.01%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPND--RTQFAMTFCGSPSFMAPEI-NKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFD---PTLS---------ESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRDIK  N+LI  D  +++ADFG+   L    D  R +   TF G+P +MAPE+  ++  Y F ADI+S G+T   M TG  P      +K + +      PTL          ++  K F  ++   + ++ SKRPTA +L+    F
Sbjct:  164 IHRDIKAGNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFF 312
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: stk25b (serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-GENE-040426-2537])

HSP 1 Score: 92.0485 bits (227), Expect = 2.536e-21
Identity = 55/133 (41.35%), Postives = 76/133 (57.14%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL  S  K F+  V+  +N+D   RPTA++L+
Sbjct:   48 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNTPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELL 176
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: stk25b (serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-GENE-040426-2537])

HSP 1 Score: 92.0485 bits (227), Expect = 5.504e-21
Identity = 55/133 (41.35%), Postives = 76/133 (57.14%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL  S  K F+  V+  +N+D   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNTPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92])

HSP 1 Score: 90.8929 bits (224), Expect = 1.217e-20
Identity = 54/133 (40.60%), Postives = 76/133 (57.14%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +   VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL  S  K F++ V+  +N++   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEHGEVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNAELHPMRVLFLIPKNNPPTLEGSYSKAFKDFVEACLNKEPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: stk24b (serine/threonine kinase 24b (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-040426-2841])

HSP 1 Score: 85.5001 bits (210), Expect = 5.366e-20
Identity = 54/141 (38.30%), Postives = 76/141 (53.90%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRDIK ANVL+ +   VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y   ADI+SLG+T   +  G  P      +  +KV F       PTL  +  K  +  V+  +N++ S RPTA++L+  ++ 
Sbjct:   43 IHRDIKAANVLLSEQGEVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSD---LHPMKVLFLIPKNNPPTLEGNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLI 176
[Close]
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: stk26 (serine/threonine protein kinase 26 [Source:ZFIN;Acc:ZDB-GENE-080516-5])

HSP 1 Score: 87.0409 bits (214), Expect = 3.001e-19
Identity = 50/132 (37.88%), Postives = 75/132 (56.82%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +   VKLADFG+   L     + +   TF G+P +MAPE+ +   Y   ADI+SLG+T   +  G  P+       ++  I  +  PTL+    K F+  V + +N+D + RPTA++L+
Sbjct:  141 IHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRE---TFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFHIPKNTPPTLNGDFSKIFKEFVDSCLNKDPAFRPTAKELL 269
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 90.8929 bits (224), Expect = 1.849e-20
Identity = 54/136 (39.71%), Postives = 76/136 (55.88%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P      +  ++V F       P+L     K F++ V+  +N+D   RPTA++L+
Sbjct:  124 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSD---LHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELL 252
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 90.8929 bits (224), Expect = 1.862e-20
Identity = 54/136 (39.71%), Postives = 76/136 (55.88%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P      +  ++V F       P+L     K F++ V+  +N+D   RPTA++L+
Sbjct:  136 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSD---LHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELL 264
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 90.5077 bits (223), Expect = 1.979e-20
Identity = 54/136 (39.71%), Postives = 76/136 (55.88%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P      +  ++V F       P+L     K F++ V+  +N+D   RPTA++L+
Sbjct:  124 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSD---LHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELL 252
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 90.5077 bits (223), Expect = 2.126e-20
Identity = 54/136 (39.71%), Postives = 76/136 (55.88%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P      +  ++V F       P+L     K F++ V+  +N+D   RPTA++L+
Sbjct:  124 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSD---LHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELL 252
[Close]
BLAST of Protein kinase vs. Ensembl Xenopus
Match: mmp9.1 (matrix metallopeptidase 9 gene 1 [Source:Xenbase;Acc:XB-GENE-876295])

HSP 1 Score: 87.8113 bits (216), Expect = 2.372e-19
Identity = 45/137 (32.85%), Postives = 76/137 (55.47%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCT---KEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            +HRD+KPAN+ +D  NNVKL DFGL R+L   +  + FA TF G+P +M+PE      Y+  +DI+SLG  +Y +   + P      KE+ +KI+      +     +E   ++ NM++     RP+ ++++   + 
Sbjct:  140 LHRDLKPANIFLDAKNNVKLGDFGLARIL---HHDSSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALSPPFTAYNQKELAEKIREGRFRRIPYRYSEELNQVITNMLHLKDYLRPSIEEILQHHLL 273
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Stk25 (serine/threonine kinase 25 (yeast) [Source:MGI Symbol;Acc:MGI:1891699])

HSP 1 Score: 91.2781 bits (225), Expect = 1.314e-20
Identity = 55/136 (40.44%), Postives = 76/136 (55.88%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+     +  ++V F       PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSD---LHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Plk1 (polo like kinase 1 [Source:MGI Symbol;Acc:MGI:97621])

HSP 1 Score: 90.5077 bits (223), Expect = 3.189e-20
Identity = 46/140 (32.86%), Postives = 81/140 (57.86%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIP---SCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSN 413
            IHRD+K  N+ +++D  VK+ DFGL   +    +R +   T CG+P+++APE+   K +SF  D++S+G  +Y ++ G  P   SC KE   +IK + + ++ +       ++++ M+  D + RPT  +L+N E F S 
Sbjct:  173 IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYEGERKK---TLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKN-EYSIPKHINPVAASLIQKMLQTDPTARPTIHELLNDEFFTSG 308
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Stk24 (serine/threonine kinase 24 [Source:MGI Symbol;Acc:MGI:2385007])

HSP 1 Score: 87.0409 bits (214), Expect = 3.932e-19
Identity = 55/144 (38.19%), Postives = 76/144 (52.78%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSN 413
            IHRDIK ANVL+ +   VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y   ADI+SLG+T   +  G  P      +  +KV F       PTL  +  K  +  V+  +N++ S RPTA++L+  +    N
Sbjct:  141 IHRDIKAANVLLSEHGEVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSE---LHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFIIRN 277
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Tssk1 (testis-specific serine kinase 1 [Source:MGI Symbol;Acc:MGI:1347557])

HSP 1 Score: 85.8853 bits (211), Expect = 6.066e-19
Identity = 49/147 (33.33%), Postives = 82/147 (55.78%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLG-RLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPA-DIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNR----DVSKRPTAQQLMNSEIFFSNIQGL 425
            +HRD+K  N+L+DKD N+KL+DFG   R L   + R   + TFCGS ++ APE+ +  PY     DI+SLGV +Y M+ G++P     I K +++  +  ++  + K      K+++ R    DV++R    +++N        +GL
Sbjct:  133 VHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDDSGRLILSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYRMLQPDVNRRLHIDEILNHCWVQPKARGL 279
[Close]
BLAST of Protein kinase vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665])

HSP 1 Score: 86.2705 bits (212), Expect = 6.103e-19
Identity = 51/140 (36.43%), Postives = 75/140 (53.57%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSN 413
            IHRDIK ANVL+ +  +VKLADFG+   L     +     TF G+P +MAPE+ +   Y   ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  +   +N+D S RPTA++L+  +    N
Sbjct:  141 IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRN---TFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKN 277
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|P50528|PLO1_SCHPO (Serine/threonine-protein kinase plo1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=plo1 PE=1 SV=1)

HSP 1 Score: 95.1301 bits (235), Expect = 7.603e-21
Identity = 53/144 (36.81%), Postives = 86/144 (59.72%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEI--NKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVD---FDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFS 410
            IHRD+K  N+++D+ NNVK+ DFGL  LLM   +R    MT CG+P+++APEI  N  + +SF  D++S GV +Y ++ G  P   KE   I +KIK +   F   +  S   E ++++ +++  D S RP+   +++ E F +
Sbjct:  160 IHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEER---KMTICGTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDIS--AEAKDLISSLLTHDPSIRPSIDDIVDHEFFHT 298
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|O00506|STK25_HUMAN (Serine/threonine-protein kinase 25 OS=Homo sapiens OX=9606 GN=STK25 PE=1 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 6.280e-20
Identity = 54/133 (40.60%), Postives = 75/133 (56.39%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q3SWY6|STK25_BOVIN (Serine/threonine-protein kinase 25 OS=Bos taurus OX=9913 GN=STK25 PE=2 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 6.466e-20
Identity = 53/132 (40.15%), Postives = 74/132 (56.06%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+   L    D      TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEQGDVKLADFGVAGQL---TDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q54PX0|Y4251_DICDI (Probable serine/threonine-protein kinase DDB_G0284251 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0284251 PE=3 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 8.559e-20
Identity = 53/145 (36.55%), Postives = 83/145 (57.24%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSNIQGLP 428
            IHRDIK +N+LI K+  +KLADFG+   +   +  +Q   +  G+P +MAPE  +    S  +DI+SLG T+  ++TGN P  T +    + +I  D  P       KEF +  +    +D ++RPTAQ+L+   IFF+ +Q +P
Sbjct:  155 IHRDIKASNILITKEGVIKLADFGVASQI---DSESQLRFSVVGTPYWMAPESIEISGCSSASDIWSLGSTMIELLTGNPPYYTLQPMAAMFRIVSDQHPPFPTDISKEFLDYFQQSFKKDPTQRPTAQELLQHPIFFT-LQKVP 295
[Close]
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q9Z2W1|STK25_MOUSE (Serine/threonine-protein kinase 25 OS=Mus musculus OX=10090 GN=Stk25 PE=1 SV=2)

HSP 1 Score: 91.2781 bits (225), Expect = 9.191e-20
Identity = 55/136 (40.44%), Postives = 76/136 (55.88%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+     +  ++V F       PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSD---LHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. TrEMBL
Match: A0A397UJ66 (Kinase-like domain-containing protein OS=Gigaspora rosea OX=44941 GN=C2G38_2022639 PE=4 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 1.395e-24
Identity = 57/142 (40.14%), Postives = 83/142 (58.45%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFD---PTLS-ESKRKEFENIVKNMVN----RDVSKRPTAQQLMNSEIF 404
            IHRD+K  N+L+D+D  V LADFG+   L    DR  F  TF G+P +MAPE+ K+  Y + ADI+S G+T   + TGN P      +K I V      PTL  +S + ++  + K M++    +D SKR TA++L+N + F
Sbjct:   92 IHRDVKAGNLLVDEDGTVSLADFGVSSSLTENGDRRGFRRTFVGTPCWMAPEVMKHADYDYKADIWSFGITSIELATGNAPFAKYSPIKVIMVTLSNDPPTLDRDSTKHKYSRVFKEMIDQSLQKDPSKRLTAEKLLNHQFF 233
[Close]
BLAST of Protein kinase vs. TrEMBL
Match: A0A1R2D4S7 (Uncharacterized protein OS=Stentor coeruleus OX=5963 GN=SteCoe_246 PE=4 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 1.774e-24
Identity = 60/140 (42.86%), Postives = 88/140 (62.86%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIK------VDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            ++RD+KP N+L+D   +VKLADFGL +  +  N+    AM+FCGSP+++APE+ K      PADIY++GVT+Y  +TGN+P  T  I +  K      V F    SES +    N++K+++N D  KRPT QQ+ + E F
Sbjct:  550 VYRDLKPLNILVDTLGHVKLADFGLAKANVSKNNP---AMSFCGSPAYLAPELIKQSGAHKPADIYTIGVTLYEFITGNLPFSTDNISRLYKEISSGRVKFPNRCSESVK----NLIKSLMNNDPEKRPTIQQVKHHEFF 682
[Close]
BLAST of Protein kinase vs. TrEMBL
Match: A0A1R2BYB7 (Uncharacterized protein OS=Stentor coeruleus OX=5963 GN=SteCoe_17673 PE=4 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 3.340e-23
Identity = 58/140 (41.43%), Postives = 87/140 (62.14%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIK------VDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            ++RD+KP N+L+D   +VKLADFGL +  +  N+    AM+FCGSP+++APE+ K      PADIY++GVT+Y  +TG++P  T  I +  K      V F    SES +    N++K+++N D  KRPT +Q+   E F
Sbjct:  550 VYRDLKPLNILVDSLGHVKLADFGLAKANVSKNNP---AMSFCGSPAYLAPELIKQSGTHKPADIYTIGVTLYEFITGSLPFRTDNISRLYKEISSGRVKFHNRCSESVK----NLIKSLMNNDPEKRPTIEQVKQHEFF 682
[Close]
BLAST of Protein kinase vs. TrEMBL
Match: A0A455B3I9 (serine/threonine-protein kinase Nek11-like OS=Physeter macrocephalus OX=9755 GN=LOC114485731 PE=3 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 7.002e-23
Identity = 53/134 (39.55%), Postives = 80/134 (59.70%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIP---SCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNS 395
            +HRD+KPANV +DK+N +++ D GL ++L       Q A T CG+P+FMAPE+ + KPY  PADI++LG  +    T  +P   S   E+ + I     P L      E   + + M+N+D SKRPT ++++NS
Sbjct:  137 LHRDLKPANVFLDKENYIRVGDLGLSKVL---EFTLQQAKTQCGTPAFMAPELCQGKPYQAPADIWALGCILVQAGTFELPFKGSNFLELTRNICHAPAPMLPRRYSLELRTLCQTMLNKDPSKRPTTKEILNS 267
[Close]
BLAST of Protein kinase vs. TrEMBL
Match: A0A455B8F8 (serine/threonine-protein kinase Nek11-like OS=Physeter macrocephalus OX=9755 GN=LOC114486088 PE=4 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 4.293e-22
Identity = 53/134 (39.55%), Postives = 80/134 (59.70%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIP---SCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNS 395
            +HRD+KPANV +DK+N +++ D GL ++L       Q A T CG+P+FMAPE+ + KPY  PADI++LG  +    T  +P   S   E+ + I     P L      E   + + M+N+D SKRPT ++++NS
Sbjct:   85 LHRDLKPANVFLDKENYIRVGDLGLSKVL---EFTLQQAKTQCGTPAFMAPELCQGKPYQAPADIWALGCILVQAGTFELPFKGSNFLELTRNICHAPAPMLPRRYSLELRTLCQTMLNKDPSKRPTTKEILNS 215
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: stk25a (serine/threonine-protein kinase 25 [Source:NCBI gene;Acc:103021644])

HSP 1 Score: 92.0485 bits (227), Expect = 4.574e-21
Identity = 55/133 (41.35%), Postives = 76/133 (57.14%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +   VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL  S  K F++ V+  +N+D   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEHGEVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGSYSKAFKDFVEACLNKDPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: stk25b (serine/threonine-protein kinase 25-like [Source:NCBI gene;Acc:103039280])

HSP 1 Score: 91.6633 bits (226), Expect = 5.418e-21
Identity = 56/136 (41.18%), Postives = 77/136 (56.62%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+     +  ++V F       PTL  S  K F+  V+  +N+D   RPTA++L+
Sbjct:  141 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSD---LHPMRVLFLIPKNPPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELL 269
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: stk25b (serine/threonine-protein kinase 25-like [Source:NCBI gene;Acc:103039280])

HSP 1 Score: 91.6633 bits (226), Expect = 6.940e-21
Identity = 56/136 (41.18%), Postives = 77/136 (56.62%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDF------DPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+     +  ++V F       PTL  S  K F+  V+  +N+D   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSD---LHPMRVLFLIPKNPPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: stk26 (serine/threonine kinase 26 [Source:NCBI gene;Acc:103024322])

HSP 1 Score: 90.1225 bits (222), Expect = 2.284e-20
Identity = 51/140 (36.43%), Postives = 77/140 (55.00%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSN 413
            IHRDIK ANVL+ +   VKLADFG+   L     + +   TF G+P +MAPE+ +   Y   ADI+SLG+T   +  G  P+       ++  I  +  PTL+    K F+  V + +N+D + RPTA++L+  +    N
Sbjct:  141 IHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRE---TFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFHIPKNTPPTLNGDFSKSFKEFVDSCLNKDPTFRPTAKELLKHKFIVKN 277
[Close]
BLAST of Protein kinase vs. Ensembl Cavefish
Match: stk26 (serine/threonine kinase 26 [Source:NCBI gene;Acc:103024322])

HSP 1 Score: 89.3521 bits (220), Expect = 4.625e-20
Identity = 51/140 (36.43%), Postives = 77/140 (55.00%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSN 413
            IHRDIK ANVL+ +   VKLADFG+   L     + +   TF G+P +MAPE+ +   Y   ADI+SLG+T   +  G  P+       ++  I  +  PTL+    K F+  V + +N+D + RPTA++L+  +    N
Sbjct:  162 IHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRE---TFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFHIPKNTPPTLNGDFSKSFKEFVDSCLNKDPTFRPTAKELLKHKFIVKN 298
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007414.1 (pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1 gene:ENSPMAG00000006689.1 transcript:ENSPMAT00000007414.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.1965 bits (217), Expect = 1.038e-20
Identity = 49/148 (33.11%), Postives = 78/148 (52.70%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMT-------GNIPSCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSNIQGL 425
            +HRDIK  N+ + K   V+L DFG+ R+L   N  T+ A T  G+P +++PEI +NKPY+  +D+++LG  +Y M T       GN+    K +V KI     P +S     E  + +  ++ RD   RP    L++  +  +  Q L
Sbjct:  125 LHRDIKSQNIFLTKAGIVQLGDFGIARVL---NSTTELARTCIGTPYYLSPEICENKPYNHKSDMWALGCVLYEMCTLRHAFEAGNM----KNLVLKIIRGSFPPVSAHYSSELRSTLSGLLRRDPRARPPVAVLLSRPLLMARAQRL 265
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: stk39 (serine threonine kinase 39 [Source:ZFIN;Acc:ZDB-GENE-140106-194])

HSP 1 Score: 88.1965 bits (217), Expect = 1.163e-20
Identity = 50/149 (33.56%), Postives = 79/149 (53.02%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPND--RTQFAMTFCGSPSFMAPEINKN-KPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFD---PTLS---ESKR------KEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRD+K  N+L+ +D  +++ADFG+   L    D  R +   TF G+P +MAPE+ +  + Y F ADI+S G+T   + +G  P      +K + +      PTL    E K       K F  ++   + +D +KRPTA +L+ S+ F
Sbjct:   27 IHRDVKAGNILLGEDGTIQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAMELASGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMVKKYGKSFRKLISQCLQKDPAKRPTAAELLKSKFF 175
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399])

HSP 1 Score: 88.5817 bits (218), Expect = 2.519e-20
Identity = 54/144 (37.50%), Postives = 80/144 (55.56%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIP---SCTKEIVKKIKV---DFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSNI 416
            I+RD+K  NVL+D++ +VK+ADFG+ +  +G  +    A TFCG+P ++APEI   + Y    D +S+GV IY M+ G  P   S   E+ + IK     +   LS+S R    NI+  +  RD +KR  A   +    FF NI
Sbjct:  375 IYRDLKLDNVLLDREGHVKIADFGMCKEHVGAGN---LATTFCGTPDYIAPEILLGRAYGTSVDWWSMGVLIYEMLIGQSPFYGSDEDELFEAIKGHTPHYPRWLSDSSR----NILSCLFERDHTKRLGAVGDIRLHPFFKNI 511
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: nek2 (NIMA-related kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-752])

HSP 1 Score: 87.4261 bits (215), Expect = 3.989e-20
Identity = 50/134 (37.31%), Postives = 73/134 (54.48%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCT----KEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMN 392
            +HRD+KPANV +D  +NVKL DFGL R+L      T FA TF G+P +M+PE      Y+  +DI+SLG  +Y  +   +P  T    K++ +KIK      +      E   I+  M+N     RP+ +Q+M 
Sbjct:  107 LHRDLKPANVFLDARHNVKLGDFGLARIL---QHDTSFAKTFVGTPYYMSPEQFSRMSYNEKSDIWSLGCLLYE-LCALVPPFTAMNQKQLAEKIKEGKFRRIPYRYSDELNEIISKMLNLKDYLRPSIEQIMQ 236
[Close]
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92])

HSP 1 Score: 86.2705 bits (212), Expect = 1.159e-19
Identity = 53/134 (39.55%), Postives = 75/134 (55.97%), Query Frame = 3 
Query:    3 IHRDIK--PANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK   ANVL+ +  +VKLADFG+   L    D      TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL  +  K F+  V + +N+D   RPTA++L+
Sbjct:  143 IHRDIKGPAANVLLSEQGDVKLADFGVAGQL---TDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTLEGNYSKAFKEFVDSCLNKDPQFRPTAKELL 273
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710])

HSP 1 Score: 86.6557 bits (213), Expect = 6.854e-20
Identity = 47/132 (35.61%), Postives = 78/132 (59.09%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTG-------NIPSCTKEIVKKIKV---DFDPTLSESKRKEFENIVKNMVNRDVSKR 368
            I+RD+KP N+L+D   ++ L DFGL +L M  ND+T    TFCG+P ++APEI   + Y+   D ++LG+ +Y MMTG       N+P   K+I+++  +    FDP          ++++  +++RD S+R
Sbjct:  464 IYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTD---TFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAA--------KDLLIGLLSRDPSRR 584
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700])

HSP 1 Score: 83.9593 bits (206), Expect = 4.134e-19
Identity = 43/128 (33.59%), Postives = 76/128 (59.38%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIP---SCTKEIVKKI---KVDFDPTLSESKRKEFENIVKNMVNRDVSKR 368
            I+RD+KP N+L+DK+ ++K+ DFG  + +  P+       T CG+P ++APE+   KPY+   D +S G+ IY M+ G  P   S T +  +KI   ++ F P  +E    + ++++  ++ RD+S+R
Sbjct:  207 IYRDLKPENILLDKNGHIKITDFGFAKYV--PD----VTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNE----DVKDLLSRLITRDLSQR 324
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 82.4185 bits (202), Expect = 1.161e-18
Identity = 41/128 (32.03%), Postives = 70/128 (54.69%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSC------TKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKR 368
            I+RD+KP N+L+DK+ ++K+ DFG  + +           T CG+P ++APE+   KPY+   D +S GV IY M+ G  P        T E +   ++ F P        + ++++K ++ RD+S+R
Sbjct:  208 IYRDLKPENILLDKNGHIKITDFGFAKYV------PDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFF----HPDAQDLLKKLITRDLSER 325
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: MKK2 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061])

HSP 1 Score: 81.6481 bits (200), Expect = 3.246e-18
Identity = 44/143 (30.77%), Postives = 75/143 (52.45%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIK--------VDFDPTLSE------SKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIKP N+L+++   +KL DFG+    +        AMTF G+  +MAPE  + +PYS   D++SLG+T+  +  G  P  + +I + +         + F P L +      S  K F + +   + +D  +RP+ +Q++
Sbjct:  339 IHRDIKPQNILLNEKGEIKLCDFGVSGEAV-----NSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQML 476
[Close]
BLAST of Protein kinase vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603])

HSP 1 Score: 81.6481 bits (200), Expect = 3.875e-18
Identity = 45/140 (32.14%), Postives = 82/140 (58.57%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEI--NKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKV-DFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRD+K  N+  D + N+K+ DFGL  +L   ++R     T CG+P+++APE+   K+  +SF  DI+SLGV +Y ++ G  P   ++   I ++IK  DF     +    E + +++++++ D  +RP+  ++M+   F
Sbjct:  201 IHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESER---KYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWF 337
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO37069 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGU2])

HSP 1 Score: 87.8113 bits (216), Expect = 1.193e-20
Identity = 47/141 (33.33%), Postives = 79/141 (56.03%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIY---NMMTGNIPSCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSNI 416
            +HRD+K  N+ + K+N VKL DFG+ R+LMG +D    A TF G+P +M+PE+ K++ Y+  +DI+SLGV +Y   N+           ++ KI     P LS+    + +     ++++D   RP+A +++       NI
Sbjct:  130 LHRDLKTRNIFL-KNNIVKLGDFGISRILMGTSD---MATTFTGTPYYMSPEVLKHEGYNHKSDIWSLGVVLYELCNLQHAFQGQSLMGVMYKIVEGELPALSDKYSSQLQAFYSRLMDKDPKLRPSANEILKHHFIAENI 266
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO49690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG02])

HSP 1 Score: 85.8853 bits (211), Expect = 8.420e-20
Identity = 44/132 (33.33%), Postives = 76/132 (57.58%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            +HRD+K  N+ + K   +K+ D G+ R+L   +D    A T  G+P +M+PE+  NKPY+  +D+++LG  +Y M T       K+   +V KI     P L +    +  +I+K+M+++D  KRP+A +L+
Sbjct:  128 LHRDLKTQNIFLTKSKIIKVGDLGIARVLESSSD---MATTLIGTPYYMSPELFSNKPYNHKSDVWALGCCLYEMCTLRHAFNAKDMSSLVYKILKGKTPPLPKQYSTDLCSIIKSMLDQDPDKRPSASRLL 256
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO35585 (Protein kinase C [Source:UniProtKB/TrEMBL;Acc:A7SL27])

HSP 1 Score: 87.4261 bits (215), Expect = 1.053e-19
Identity = 39/81 (48.15%), Postives = 54/81 (66.67%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIP 245
            I+RD+K  NVL+D D ++KLADFG+ +  M P   T    TFCG+P ++APEI + +PY F  D ++LGV +Y MM G  P
Sbjct:  504 IYRDLKLDNVLLDADGHIKLADFGMCKENMAPGKTT---TTFCGTPDYIAPEILQEQPYGFSVDWWALGVLMYEMMAGQPP 581
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO37951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE61])

HSP 1 Score: 85.1149 bits (209), Expect = 2.356e-19
Identity = 44/139 (31.65%), Postives = 79/139 (56.83%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGR-LLMGPNDRTQFAMTFCGSPSFMAPEINKNKPY-SFPADIYSLGVTIYNMMTGNIP-------SCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMN 392
            +HRD+K  N+L+DKD N+ ++DFG  R  L     + + + T+CGS ++ APEI K   Y +  AD++S+GV +Y M+ G +P       S  +++ K++       LS++ +     I+  M+  ++ +R T +QL+ 
Sbjct:  172 VHRDLKCENLLLDKDLNIIISDFGFARDCLTTATGKKKLSHTYCGSYAYAAPEILKGIAYDATLADVWSMGVILYTMLCGRLPFDDSNLRSLLQQVHKRVTFSSRVKLSDAAK----AIIHKMLTWNLPERITVEQLLQ 306
[Close]
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO37413 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFU9])

HSP 1 Score: 83.5741 bits (205), Expect = 5.637e-19
Identity = 48/133 (36.09%), Postives = 75/133 (56.39%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVK---KIKVD-FDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            +HRD+KPANV +D + NVKL DFGL R+L   +  T FA TF G+P +M+PE    + Y+  +DI+SLG  +Y +   + P    + ++   KIKV  F P  S         ++ +M+  +   RP+  +L+
Sbjct:  138 LHRDLKPANVFLDANMNVKLGDFGLARVL---SHDTSFAKTFVGTPYYMSPEQVNKRSYNEKSDIWSLGCLMYELCALSPPFTAMDQIRLEAKIKVGRFHPIPSHYS-SSLSQLINSMLQVNDEMRPSIDELL 266
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: stk25b (serine/threonine kinase 25 [Source:NCBI gene;Acc:101157729])

HSP 1 Score: 90.1225 bits (222), Expect = 2.179e-20
Identity = 54/133 (40.60%), Postives = 75/133 (56.39%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNTPPTLEGPYSKPFKEFVEACLNKDPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: stk25b (serine/threonine kinase 25 [Source:NCBI gene;Acc:101157729])

HSP 1 Score: 90.1225 bits (222), Expect = 2.183e-20
Identity = 54/133 (40.60%), Postives = 75/133 (56.39%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAM-TFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKE---IVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +  +VKLADFG+     G    TQ    TF G+P +MAPE+ K   Y F ADI+SLG+T   +  G  P+       ++  I  +  PTL     K F+  V+  +N+D   RPTA++L+
Sbjct:  137 IHRDIKAANVLLSEQGDVKLADFGVA----GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNTPPTLEGPYSKPFKEFVEACLNKDPRFRPTAKELL 265
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: nek2 (NIMA related kinase 2 [Source:NCBI gene;Acc:101168418])

HSP 1 Score: 88.1965 bits (217), Expect = 1.214e-19
Identity = 47/137 (34.31%), Postives = 76/137 (55.47%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCT---KEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            +HRD+KPAN+ +D + NVKL DFGL R+L   N  T FA TF G+P +M+PE      Y+  +DI+SLG  +Y +   + P      KE+ +KI+      +     +E  +++  M+N     RP+ + ++ S + 
Sbjct:  138 LHRDLKPANIFLDANQNVKLGDFGLARIL---NHDTSFAKTFVGTPYYMSPEQINRMSYNEKSDIWSLGCLLYELCALSPPFTAYNQKELAEKIREGKFRRIPFRYSEELNSLISRMLNLKDYLRPSVESILQSSLL 271
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: ENSORLT00000045138.1 (serine/threonine kinase 26 [Source:NCBI gene;Acc:101158974])

HSP 1 Score: 87.4261 bits (215), Expect = 1.901e-19
Identity = 51/135 (37.78%), Postives = 75/135 (55.56%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFD------PTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +   VKLADFG+   L     + +   TF G+P +MAPE+ +   Y   ADI+SLG+T   +  G  P+     +  ++V F       PTLS    K F+   +  +N+D + RPTA++L+
Sbjct:  134 IHRDIKAANVLLSEHGQVKLADFGVAGQLTDTQIKRE---TFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSD---MHPMRVLFHIPKSPPPTLSGDFSKSFKEFTEACLNKDPAFRPTAKELL 262
[Close]
BLAST of Protein kinase vs. Ensembl Medaka
Match: ENSORLT00000004137.2 (serine/threonine kinase 26 [Source:NCBI gene;Acc:101158974])

HSP 1 Score: 87.0409 bits (214), Expect = 2.160e-19
Identity = 51/135 (37.78%), Postives = 75/135 (55.56%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFD------PTLSESKRKEFENIVKNMVNRDVSKRPTAQQLM 389
            IHRDIK ANVL+ +   VKLADFG+   L     + +   TF G+P +MAPE+ +   Y   ADI+SLG+T   +  G  P+     +  ++V F       PTLS    K F+   +  +N+D + RPTA++L+
Sbjct:  128 IHRDIKAANVLLSEHGQVKLADFGVAGQLTDTQIKRE---TFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSD---MHPMRVLFHIPKSPPPTLSGDFSKSFKEFTEACLNKDPAFRPTAKELL 256
[Close]
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000017260.1 (SMESG000017260.1)

HSP 1 Score: 303.908 bits (777), Expect = 6.773e-98
Identity = 143/143 (100.00%), Postives = 143/143 (100.00%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSNIQGLPR 431
            IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSNIQGLPR
Sbjct:  669 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSNIQGLPR 811
[Close]
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000017258.1 (SMESG000017258.1)

HSP 1 Score: 169.474 bits (428), Expect = 4.368e-48
Identity = 82/137 (59.85%), Postives = 103/137 (75.18%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSN 413
            IHRDIKPANVLIDK+NNVKL DFG+GR+L G  ++T FA T CG+P++M PE+   KPYSF ADIYSLG TIY+MMTGNIP   K++ K I+  F  ++   ++K+FE I+K  VN D S RPTAQ+LMN  I +SN
Sbjct:  570 IHRDIKPANVLIDKNNNVKLVDFGIGRILEGTRNQTVFARTCCGTPAYMGPEVFNEKPYSFSADIYSLGATIYHMMTGNIPDPEKDLFKVIQEGFSQSVKSIQQKKFEFILKWTVNPDASMRPTAQKLMNEFINYSN 706
[Close]
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000022974.1 (SMESG000022974.1)

HSP 1 Score: 113.235 bits (282), Expect = 2.079e-28
Identity = 60/142 (42.25%), Postives = 86/142 (60.56%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEINKNKPYSFPADIYSLGVTIYNMMTG-------NIPSCTKEIVKKIKVDFDPTLSESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFF 407
            IHRDI P+N+L+D + N+KL DFG  R++     +   A TFCG+ +++APEI  ++ YSFPADI+S+G TI++M+ G       +I      I+K  K+DF P    S+R     IVK M+N   S RPTA  L+  E+F 
Sbjct:  365 IHRDITPSNILLDANLNIKLTDFGFSRVVKDTGTQN-CAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRR--MSTIVKEMLNYKPSNRPTAASLLKHELFL 503
[Close]
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000016973.1 (SMESG000016973.1)

HSP 1 Score: 108.612 bits (270), Expect = 8.257e-27
Identity = 61/142 (42.96%), Postives = 90/142 (63.38%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEI---NKNKPYSFPADIYSLGVTIYNMMTGNIPSCTK---EIVKKIKVDFDPTL--SESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRDIKPAN+L++++N VKL DFG+ RLL G         T CG+P FMAPE+   + N PY+  ADI+S+G T+ NM+TG+ P+  K   +++ +I  D    L  SE   KE +  ++ M+N D ++RPTA +L+   +F
Sbjct:  385 IHRDIKPANILLNQENCVKLTDFGVSRLLCG---ELSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLIEIANDKKLQLPSSEMMSKEMKTFIEKMMNPDPNERPTATELLTLSLF 523
[Close]
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000017084.1 (SMESG000017084.1)

HSP 1 Score: 104.76 bits (260), Expect = 2.619e-25
Identity = 57/142 (40.14%), Postives = 90/142 (63.38%), Query Frame = 3 
Query:    3 IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMAPEI---NKNKPYSFPADIYSLGVTIYNMMTGNIP--SCT-KEIVKKIKVDFDPTLSESK--RKEFENIVKNMVNRDVSKRPTAQQLMNSEIF 404
            IHRDIKPAN+L+D+ NN+KLADFG+ R LM     +  A TF G+ +F +PE+   + + PY+  +DI+S+G T+ NM++G  P   C   +++ KI  +    L ES+    E ++ ++ M+N D  +RPTA QL+  ++F
Sbjct:  563 IHRDIKPANILMDQLNNIKLADFGVARSLMRTTGLSTRAKTFVGTVNFTSPEVLNADDDSPYTVSSDIWSVGATVINMISGKAPLHDCLPPKVIIKISSEKKLELPESQLMSAEMKSFIEEMLNPDPDQRPTAAQLLKLKLF 704
The following BLAST results are available for this feature:
BLAST of Protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
STK254.047e-2239.71serine/threonine kinase 25 [Source:HGNC Symbol;Acc... [more]
STK251.153e-2140.60serine/threonine kinase 25 [Source:HGNC Symbol;Acc... [more]
STK255.358e-2140.15serine/threonine kinase 25 [Source:HGNC Symbol;Acc... [more]
STK255.358e-2140.15serine/threonine kinase 25 [Source:HGNC Symbol;Acc... [more]
STK255.951e-2140.15serine/threonine kinase 25 [Source:HGNC Symbol;Acc... [more]
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BLAST of Protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
aak-29.022e-2035.515'-AMP-activated protein kinase catalytic subunit ... [more]
aak-29.022e-2035.515'-AMP-activated protein kinase catalytic subunit ... [more]
aak-21.121e-1936.235'-AMP-activated protein kinase catalytic subunit ... [more]
aak-21.166e-1936.235'-AMP-activated protein kinase catalytic subunit ... [more]
gck-31.645e-1933.33Germinal center kinase 3 [Source:UniProtKB/Swiss-... [more]
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BLAST of Protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GckIII4.846e-2037.88gene:FBgn0266465 transcript:FBtr0083399[more]
fray1.292e-1934.23gene:FBgn0023083 transcript:FBtr0083638[more]
fray1.292e-1934.23gene:FBgn0023083 transcript:FBtr0347418[more]
fray1.292e-1934.23gene:FBgn0023083 transcript:FBtr0290210[more]
fray1.292e-1934.23gene:FBgn0023083 transcript:FBtr0290107[more]
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BLAST of Protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk25b2.536e-2141.35serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-G... [more]
stk25b5.504e-2141.35serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-G... [more]
stk25a1.217e-2040.60serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-G... [more]
stk24b5.366e-2038.30serine/threonine kinase 24b (STE20 homolog, yeast)... [more]
stk263.001e-1937.88serine/threonine protein kinase 26 [Source:ZFIN;Ac... [more]
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BLAST of Protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk251.849e-2039.71serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
stk251.862e-2039.71serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
stk251.979e-2039.71serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
stk252.126e-2039.71serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
mmp9.12.372e-1932.85matrix metallopeptidase 9 gene 1 [Source:Xenbase;A... [more]
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BLAST of Protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Stk251.314e-2040.44serine/threonine kinase 25 (yeast) [Source:MGI Sym... [more]
Plk13.189e-2032.86polo like kinase 1 [Source:MGI Symbol;Acc:MGI:9762... [more]
Stk243.932e-1938.19serine/threonine kinase 24 [Source:MGI Symbol;Acc:... [more]
Tssk16.066e-1933.33testis-specific serine kinase 1 [Source:MGI Symbol... [more]
Stk266.103e-1936.43serine/threonine kinase 26 [Source:MGI Symbol;Acc:... [more]
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BLAST of Protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P50528|PLO1_SCHPO7.603e-2136.81Serine/threonine-protein kinase plo1 OS=Schizosacc... [more]
sp|O00506|STK25_HUMAN6.280e-2040.60Serine/threonine-protein kinase 25 OS=Homo sapiens... [more]
sp|Q3SWY6|STK25_BOVIN6.466e-2040.15Serine/threonine-protein kinase 25 OS=Bos taurus O... [more]
sp|Q54PX0|Y4251_DICDI8.559e-2036.55Probable serine/threonine-protein kinase DDB_G0284... [more]
sp|Q9Z2W1|STK25_MOUSE9.191e-2040.44Serine/threonine-protein kinase 25 OS=Mus musculus... [more]
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BLAST of Protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A397UJ661.395e-2440.14Kinase-like domain-containing protein OS=Gigaspora... [more]
A0A1R2D4S71.774e-2442.86Uncharacterized protein OS=Stentor coeruleus OX=59... [more]
A0A1R2BYB73.340e-2341.43Uncharacterized protein OS=Stentor coeruleus OX=59... [more]
A0A455B3I97.002e-2339.55serine/threonine-protein kinase Nek11-like OS=Phys... [more]
A0A455B8F84.293e-2239.55serine/threonine-protein kinase Nek11-like OS=Phys... [more]
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BLAST of Protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk25a4.574e-2141.35serine/threonine-protein kinase 25 [Source:NCBI ge... [more]
stk25b5.418e-2141.18serine/threonine-protein kinase 25-like [Source:NC... [more]
stk25b6.940e-2141.18serine/threonine-protein kinase 25-like [Source:NC... [more]
stk262.284e-2036.43serine/threonine kinase 26 [Source:NCBI gene;Acc:1... [more]
stk264.625e-2036.43serine/threonine kinase 26 [Source:NCBI gene;Acc:1... [more]
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BLAST of Protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000007414.11.038e-2033.11pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1... [more]
stk391.163e-2033.56serine threonine kinase 39 [Source:ZFIN;Acc:ZDB-GE... [more]
PRKCD2.519e-2037.50protein kinase C delta [Source:HGNC Symbol;Acc:HGN... [more]
nek23.989e-2037.31NIMA-related kinase 2 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
stk25a1.159e-1939.55serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of Protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
YPK26.854e-2035.61Protein kinase similar to S/T protein kinase Ypk1p... [more]
TPK14.134e-1933.59cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK31.161e-1832.03cAMP-dependent protein kinase catalytic subunit; p... [more]
MKK23.246e-1830.77MAPKK involved in the protein kinase C signaling p... [more]
CDC53.875e-1832.14Polo-like kinase; controls targeting and activatio... [more]
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BLAST of Protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO370691.193e-2033.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO496908.420e-2033.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO355851.053e-1948.15Protein kinase C [Source:UniProtKB/TrEMBL;Acc:A7S... [more]
EDO379512.356e-1931.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO374135.637e-1936.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk25b2.179e-2040.60serine/threonine kinase 25 [Source:NCBI gene;Acc:1... [more]
stk25b2.183e-2040.60serine/threonine kinase 25 [Source:NCBI gene;Acc:1... [more]
nek21.214e-1934.31NIMA related kinase 2 [Source:NCBI gene;Acc:101168... [more]
ENSORLT00000045138.11.901e-1937.78serine/threonine kinase 26 [Source:NCBI gene;Acc:1... [more]
ENSORLT00000004137.22.160e-1937.78serine/threonine kinase 26 [Source:NCBI gene;Acc:1... [more]
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BLAST of Protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000017260.16.773e-98100.00SMESG000017260.1[more]
SMESG000017258.14.368e-4859.85SMESG000017258.1[more]
SMESG000022974.12.079e-2842.25SMESG000022974.1[more]
SMESG000016973.18.257e-2742.96SMESG000016973.1[more]
SMESG000017084.12.619e-2540.14SMESG000017084.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005745 ID=SMED30005745|Name=Protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=775bp
TTATTCATCGAGATATAAAGCCGGCCAATGTGCTGATAGATAAGGACAAT
AATGTGAAATTGGCAGACTTCGGATTGGGTCGGCTTTTGATGGGGCCAAA
TGACAGGACGCAATTTGCAATGACATTTTGTGGAAGTCCTTCATTTATGG
CTCCAGAAATTAATAAAAATAAACCTTACTCATTTCCGGCAGATATTTAT
TCTTTGGGAGTTACGATTTACAATATGATGACGGGAAACATTCCCAGTTG
CACTAAGGAAATTGTGAAAAAGATAAAGGTAGATTTCGATCCAACGTTAT
CCGAATCTAAACGGAAAGAGTTTGAAAACATTGTAAAGAATATGGTAAAT
AGGGACGTTTCCAAGCGACCGACTGCGCAGCAATTAATGAATTCAGAAAT
ATTCTTTTCTAACATTCAAGGACTTCCAAGATATTTTCTAAAATAAATTT
TAAATATTAAAAAAAAAAAATTTTTTTGGATTAATTGAAATATTTATAAA
CGCGTTGGTGGCGAAGAGTTGAAACGTAGGCCGCTGATCCAGTCTGAAAG
TCACGGCAGCGTGACTGATTCTAAAATCAACTTGATTTTTTATAATAGAT
TATTTTGTTGATGTACATAATTGTAATAAAAAATGATTTTTTTCTTAATA
ATATTGCACGAATTACCAATATAATTCTGTTATTATTCTTAAACGGAAAG
GCTTTTTGTAATAGAGCTTTAATATTTTATTAAAATTAAAACAAAATTTA
CAAGCCAATGTCAATTGTCATTAGG
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protein sequence of SMED30005745-orf-1

>SMED30005745-orf-1 ID=SMED30005745-orf-1|Name=SMED30005745-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=148bp
IHRDIKPANVLIDKDNNVKLADFGLGRLLMGPNDRTQFAMTFCGSPSFMA
PEINKNKPYSFPADIYSLGVTIYNMMTGNIPSCTKEIVKKIKVDFDPTLS
ESKRKEFENIVKNMVNRDVSKRPTAQQLMNSEIFFSNIQGLPRYFLK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000018Category 4 cell
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 1..134
e-value: 7.8E-8
score: -23.4
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 1..134
e-value: 2.6E-33
score: 115.5
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 1..135
score: 27.835
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 1..143
e-value: 1.8E-40
score: 141.1
NoneNo IPR availablePANTHERPTHR24346:SF30NON-SPECIFIC SERINE/THREONINE PROTEIN KINASEcoord: 1..132
NoneNo IPR availablePANTHERPTHR24346MAP/MICROTUBULE AFFINITY-REGULATING KINASEcoord: 1..132
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 1..137