Cytoplasmic dynein 2 heavy chain 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30005692 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 23Note: Hover over icons to view figure legend
Homology
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Human
Match: DYNC2H1 (dynein cytoplasmic 2 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2962]) HSP 1 Score: 4532.63 bits (11755), Expect = 0.000e+0 Identity = 2338/4334 (53.95%), Postives = 3110/4334 (71.76%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHFPNQNSKFVNE---ECLD--KFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVP-------PTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAE-ITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLS--ADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLL-EMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVS-LLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVV------NGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RK IF T+++F + + CL+ F D+ + +L V+ D FSN + D LVF K P +IT +N++ I+V+++ E+PISSLY ++ ++ P+LL D DPK+Q L+SELE GLG ++R+ + +K + E GI + DE FW + + ++ R N + + E + S SL E +E +++D+W+ +T + +YP+SRM L++II R +Q +L L WED Y LVKESL I +C W+ +C+ L + W++Y+PH W + + + RL E+ ++RT+HE+ LP E + + F+ F + P+ YNPYTEP+WK AV ++ + I PAE I +LK E + PQQLL+ F +Y +L+ RP IS L+ ERETLLA+LV K R DF +R R +P KN S+ ++ IVW +QLE K+++ + I +L DL GF F + K+ L+++ + QEQF+ W++++ L DS + G+ ++ R+MEL DGLL V+YSDRLV L+REVR LS LG+ I + A+ QKF +A+ILKQVA FYN+I+ QMI Q+ MML +A+ FE+++K+ + S K+ + W+NP+EL +I KLQ A+ + ++NR LRK H CEK+V LM IDLLRQQQ+WKD L E+R L +E Q + WK+H +HQLYKALE+QY +GLEALNENLPEI +DL Y+QGRLQF P FEEI++KY++EMK+FI +PNQFKG+ ++ G++ IF +I+RNA+GF+ + KAE LF+RLSA L++ KEWI++G +D+E V++H + D+EKNFKA+K KGKE E+LP+ +K+DC+ +NC P+K +D LIQ +FD L+ SL+K+I+ + +D ++T ++++L+ PQ+++EI +A L +++ + + I ++E N LLRTVAGGG++T+S L+ KWDKFELMMES Q+M+++QIEVMK N+ SR + + Q++ KF RW LKPG D++++G + + IK+KK+E ++L + + L DC HF++E F+L I KDI+ +W+ +EE+Q G Q +A EDW++FR++ YLFEEFL W ++LR E + MT++LQ E+D YK +IPILK++RGE LS DHWL++FRLL +PRG +LE L +L A I+ A +K+LN +AQGEVTIREA+REL+LWG GAVF L++Y DSQ+ ++ LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK ++WE KLA+LDEYLQNLN IQRKWVYLEPIFG+ ALPKE++RF RVDEDFRSIM+D+ ++NRV +L + +G++N L T++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQSTNP VI+SHLKKLF GI V F++ +HI MKSL+GEVV +N+V +++ VE WL +L EMK TL L + R S + ++ +PSQILCL+E I FT E + ++++ ++ +LV KL YTN S ++ + +LKLK+LILD +HNID++ QL + +W W KQLRFY KS D C +QMVD+EF YTYEYQGNA KLV+TPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEE+VLSAVSMQIQ IQD +KN LL + V V+ NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMS PDN+LIAEVIL S+GFK+AK L RKLVAIFNLSRELLTPQQHYDWGLRALKTVL+G+ NLL +++KS N E+ ++VQALR+NT+SK T+ D F++LIKDVFP I++KE+EYD L++A+++V +E N + Q KK LE+YEQL QRMGVVIVGPSG+GKST+W++LR AL K G+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQ++ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+ SL+ SWL+ Q ++ L ++ D+F K+L W+ K+N++ + TS VGTV NGLS+L ++ F + LI+GLGGNLN SR F V+ E P+ +K ++ Y++ + RL TY + E+L+ D + + P+I T D+QR LDYFK WL+SDT+QPFIL GPEGCGK ++L + F +L+S Q+ T+HCSAQTT H+LQKL+Q C++I++NTGRVYRPK+ ERL+LYLKDINLPKLDKWGTS L++FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ +GR L+TRFTSIVRLCSI YP ++QL IY AYL+PVL + + H IW +SK+ LLA +M++VY Q+++KFTVDDYSHY FTP LTQWVL L RYDL S N + +LEIV+YE+ R+F+D++V + D IL + +W ++ D+++D ++VTWG+R A A P GK LGKL S LKD I +GL+ Y R+ ++LDI+LF EV + ++++DRVL+ PGGS+LLAG+SGVGRRT + LVSHMH L SPK+ RGYELKQFKNDLK LQ AG+E + +VLLLED+QF+ P +LE+INSLL+SGEVPGLYT EELEP+L+ LKD A++ G G + NYF RI+ LHI+LIMD +N NF+INC+SNPA K C V W+E WS SM KIP ML ++ E + + K D L S+ L +H++C +T Y+ F+ +Y I KK E+ RQ+H+Q G+ K++EAK +V EL KA EQS LL KQ EAD AL+ IT MQ A+E+K E+E+L + EE V + +RK IDDEL ++P V +A+ AV +IK LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+I TFDAR I++E R VEELL + K SFDPKNAKRAS AAAPLAAWVKAN++YS+ LE+I PLE EQ L+ NL+ E + + LE+ ++ V + V+ ++ F+ T++AAKLE E+ A ETI AAE L+ +L+ E +RWN Q+VE+ EL+ L ++ LAAA + Y+ ++PE RK ++ W + GLEKFD+R+FL TE EQL WK EGL SD+LS+ENALVILQ + PFLIDPSS AT WLK H KD +LE++NQQDSNF T LEL+VRFGKTLIIQE+DG+EPVLYPLLR DL++QGPR VVQ+GDK+IDYN +F+LFL+TRNP P +PPDA +IV+ VNFTTT++GL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+K+EESLL+ LA + GNIL NKDL+ SLN+TK SS I +SL+ES KLQ+SLD+ERDA+LPLAE S ++F+ISDLSKINNMYRFSL +FLRLFQRAL + S ++ R SLI+ L+ +VYEY+CR +FK+D+LMFALH P+LF+ EW+ FTG + D K+D + P WID +R+ A++ L A+P L+ L +D LW + +S CE+E P L K+SLFQ+IL++QALRPDRLQSA++ F C L LK +SP +NL ++Y+ ET+ EPILIIISPGADPSQ+LQEL+ E Y+QVAMGQGQAD+ + +L +C++NGDWLCLKNLHLV SWLPVLEKELN+L+P FRLW+TAE H F+ ILLQSSLKITYE+PPG+K NL+R+Y++W+ + ISK + RA+ALFSLAWFHA QERRN+IPQGWTKFYEFS++DLRAG I+D++ + +++QW+F+HGL ENAI+GGR+DN FD+RVL SY+K++FN SV+ N F + LP + S DY A+I ++ + + PSFF LP NI RSSQR+ISSQVI QLRIL R G+KFD++IWS EL+PVLN WK LNQ N+I +P R SP+++F+ LE++N+I+LV+ VH SL +LSKV++G+ LL+ EVQ L+ LL + P W +WEGPE+P Y+R L+ +A A++ W + +EK LLS LDL ELFHPDTFLNALRQ TAR + S+D LKFV W G AK +KI L +EGC FDG ++E DS S+ + P +GW+ ++ YS D+ ISLP+Y RD++VT ID+PC G QD+WIQ G ALFLK+
Sbjct: 7 DVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGISFSNTIEFGDTKDKVLVFFKLRPEVITDENLHDNILVSSMLESPISSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRRSDTNLTKLKFKEDDTRGILTPSDEFQFWIEQAHRGNKQISKERANYFKELFETIAREFYNLDSLSLLEVVDLVETTQDVVDDVWR-QTEHDHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNHLTGQVWQRYVPHPWKNEKYFPET-LDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTRVFEPFTGLNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDS--PQQLLQAFLKYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCR--GIPGDASGPLSGKNLSEVVNSIVWVRQLELKVDDTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDIQSGLSDSRS-GLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDLLRQQQRWKDGLQELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALNENLPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEA--GDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGA---VDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKS-DHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNAN-----------ESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQNDYVVETSLVGTVMNGLSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP--MDTYYDSTRGRLATYVLKKPEDLTADDFSNG--LTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLL-IHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYK-ETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGA-KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQG--SPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVYTSAERDRVVTNIDVPC-GGNQDQWIQCGAALFLKN 4306
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Human
Match: DYNC2H1 (dynein cytoplasmic 2 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2962]) HSP 1 Score: 4526.85 bits (11740), Expect = 0.000e+0 Identity = 2339/4341 (53.88%), Postives = 3111/4341 (71.67%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHFPNQNSKFVNE---ECLD--KFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVP-------PTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAE-ITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLS--ADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLL-EMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVS-LLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGI-------LIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVV------NGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RK IF T+++F + + CL+ F D+ + +L V+ D FSN + D LVF K P +IT +N++ I+V+++ E+PISSLY ++ ++ P+LL D DPK+Q L+SELE GLG ++R+ + +K + E GI + DE FW + + ++ R N + + E + S SL E +E +++D+W+ +T + +YP+SRM L++II R +Q +L L WED Y LVKESL I +C W+ +C+ L + W++Y+PH W + + + RL E+ ++RT+HE+ LP E + + F+ F + P+ YNPYTEP+WK AV ++ + I PAE I +LK E + PQQLL+ F +Y +L+ RP IS L+ ERETLLA+LV K R DF +R R +P KN S+ ++ IVW +QLE K+++ + I +L DL GF F + K+ L+++ + QEQF+ W++++ L DS + G+ ++ R+MEL DGLL V+YSDRLV L+REVR LS LG+ I + A+ QKF +A+ILKQVA FYN+I+ QMI Q+ MML +A+ FE+++K+ + S K+ + W+NP+EL +I KLQ A+ + ++NR LRK H CEK+V LM IDLLRQQQ+WKD L E+R L +E Q + WK+H +HQLYKALE+QY +GLEALNENLPEI +DL Y+QGRLQF P FEEI++KY++EMK+FI +PNQFKG+ ++ G++ IF +I+RNA+GF+ + KAE LF+RLSA L++ KEWI++G +D+E V++H + D+EKNFKA+K KGKE E+LP+ +K+DC+ +NC P+K +D LIQ +FD L+ SL+K+I+ + +D ++T ++++L+ PQ+++EI +A L +++ + + I ++E N LLRTVAGGG++T+S L+ KWDKFELMMES Q+M+++QIEVMK N+ SR + + Q++ KF RW LKPG D++++G + + IK+KK+E ++L + + L DC HF++E F+L I KDI+ +W+ +EE+Q G Q +A EDW++FR++ YLFEEFL W ++LR E + MT++LQ E+D YK +IPILK++RGE LS DHWL++FRLL +PRG +LE L +L A I+ A +K+LN +AQGEVTIREA+REL+LWG GAVF L++Y DSQ+ ++ LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK ++WE KLA+LDEYLQNLN IQRKWVYLEPIFG+ ALPKE++RF RVDEDFRSIM+D+ ++NRV +L + +G++N L T++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQSTNP VI+SHLKKLF GI V F++ +HI MKSL+GEVV +N+V +++ VE WL +L EMK TL L + R S + ++ +PSQILCL+E I FT E + ++++ ++ +LV KL YTN S ++ + +LKLK+LILD +HNID++ QL + +W W KQLRFY KS D C +QMVD+EF YTYEYQGNA KLV+TPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEE+VLSAVSMQIQ IQD +KN LL + V V+ NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMS PDN+LIAEVIL S+GFK+AK L RKLVAIFNLSRELLTPQQHYDWGLRALKTVL+G+ NLL +++KS N E+ ++VQALR+NT+SK T+ D F++LIKDVFP I++KE+EYD L++A+++V +E N + Q KK LE+YEQL QRMGVVIVGPSG+GKST+W++LR AL K G+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQ++ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+ SL+ SWL+ Q ++ L ++ D+F K+L W+ K+N++ + TS VGTV NGLS+L ++ F + LI+GLGGNLN SR F V+ E P+ +K ++ Y++ + RL TY + E+L+ D + + P+I T D+QR LDYFK WL+SDT+QPFIL GPEGCGK ++L + F +L+S Q+ T+HCSAQTT H+LQKL+Q C++I++NTGRVYRPK+ ERL+LYLKDINLPKLDKWGTS L++FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ +GR L+TRFTSIVRLCSI YP ++QL IY AYL+PVL + + H IW +SK+ LLA +M++VY Q+++KFTVDDYSHY FTP LTQWVL L RYDL S N + +LEIV+YE+ R+F+D++V + D IL + +W ++ D+++D ++VTWG+R A A P GK LGKL S LKD I +GL+ Y R+ ++LDI+LF EV + ++++DRVL+ PGGS+LLAG+SGVGRRT + LVSHMH L SPK+ RGYELKQFKNDLK LQ AG+E + +VLLLED+QF+ P +LE+INSLL+SGEVPGLYT EELEP+L+ LKD A++ G G + NYF RI+ LHI+LIMD +N NF+INC+SNPA K C V W+E WS SM KIP ML ++ E + + K D L S+ L +H++C +T Y+ F+ +Y I KK E+ RQ+H+Q G+ K++EAK +V EL KA EQS LL KQ EAD AL+ IT MQ A+E+K E+E+L + EE V + +RK IDDEL ++P V +A+ AV +IK LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+I TFDAR I++E R VEELL + K SFDPKNAKRAS AAAPLAAWVKAN++YS+ LE+I PLE EQ L+ NL+ E + + LE+ ++ V + V+ ++ F+ T++AAKLE E+ A ETI AAE L+ +L+ E +RWN Q+VE+ EL+ L ++ LAAA + Y+ ++PE RK ++ W + GLEKFD+R+FL TE EQL WK EGL SD+LS+ENALVILQ I + PFLIDPSS AT WLK H KD +LE++NQQDSNF T LEL+VRFGKTLIIQE+DG+EPVLYPLLR DL++QGPR VVQ+GDK+IDYN +F+LFL+TRNP P +PPDA +IV+ VNFTTT++GL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+K+EESLL+ LA + GNIL NKDL+ SLN+TK SS I +SL+ES KLQ+SLD+ERDA+LPLAE S ++F+ISDLSKINNMYRFSL +FLRLFQRAL + S ++ R SLI+ L+ +VYEY+CR +FK+D+LMFALH P+LF+ EW+ FTG + D K+D + P WID +R+ A++ L A+P L+ L +D LW + +S CE+E P L K+SLFQ+IL++QALRPDRLQSA++ F C L LK +SP +NL ++Y+ ET+ EPILIIISPGADPSQ+LQEL+ E Y+QVAMGQGQAD+ + +L +C++NGDWLCLKNLHLV SWLPVLEKELN+L+P FRLW+TAE H F+ ILLQSSLKITYE+PPG+K NL+R+Y++W+ + ISK + RA+ALFSLAWFHA QERRN+IPQGWTKFYEFS++DLRAG I+D++ + +++QW+F+HGL ENAI+GGR+DN FD+RVL SY+K++FN SV+ N F + LP + S DY A+I ++ + + PSFF LP NI RSSQR+ISSQVI QLRIL R G+KFD++IWS EL+PVLN WK LNQ N+I +P R SP+++F+ LE++N+I+LV+ VH SL +LSKV++G+ LL+ EVQ L+ LL + P W +WEGPE+P Y+R L+ +A A++ W + +EK LLS LDL ELFHPDTFLNALRQ TAR + S+D LKFV W G AK +KI L +EGC FDG ++E DS S+ + P +GW+ ++ YS D+ ISLP+Y RD++VT ID+PC G QD+WIQ G ALFLK+
Sbjct: 7 DVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGISFSNTIEFGDTKDKVLVFFKLRPEVITDENLHDNILVSSMLESPISSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRRSDTNLTKLKFKEDDTRGILTPSDEFQFWIEQAHRGNKQISKERANYFKELFETIAREFYNLDSLSLLEVVDLVETTQDVVDDVWR-QTEHDHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNHLTGQVWQRYVPHPWKNEKYFPET-LDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTRVFEPFTGLNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDS--PQQLLQAFLKYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCR--GIPGDASGPLSGKNLSEVVNSIVWVRQLELKVDDTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDIQSGLSDSRS-GLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDLLRQQQRWKDGLQELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALNENLPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEA--GDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGA---VDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKS-DHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNAN-----------ESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQNDYVVETSLVGTVMNGLSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP--MDTYYDSTRGRLATYVLKKPEDLTADDFSNG--LTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLL-IHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYK-ETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGA-KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQG--SPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVYTSAERDRVVTNIDVPC-GGNQDQWIQCGAALFLKN 4313
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Human
Match: DNAH2 (dynein axonemal heavy chain 2 [Source:HGNC Symbol;Acc:HGNC:2948]) HSP 1 Score: 1213.36 bits (3138), Expect = 0.000e+0 Identity = 962/3538 (27.19%), Postives = 1707/3538 (48.25%), Query Frame = 3
Query: 2787 ITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLR----TVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNL---------EKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWS-------QFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIF----GKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNK-----DIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLR-MSNQSNYGINADKYPSQILCLSEMIHFTA---RC----EELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQT-------VKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDW-------IAKRNEFTISTSNVGTVYNGLSNLKAIKNKAH-----------FSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQ--VTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPK-HPIWSQNSKVKL-LANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTS-EYLKDTIDRGLLQY--SRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLAN-----ESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSY----FLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISE--------------AKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRC-KDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKM-QLWMEK------TGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF--TGTFISDKSDRNITVPKWI-DA--DRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLK---PHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANA-LFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQ---LPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTD-------SP--VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNV--SAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYY------DILRDKIVTKIDIPCQSGQQDKWIQSGVALFL 12986
+ ++C+ +K S+ + LR+ G + + YL + + +S+ PQ ++E+ + D + + +QI + +L V ++ + L +W F+ + + M+++ E KT ++ F++ + ++ G + G A Q EE ++ NL KD ++ + E + + EI +D ++N W Q E +T L FR L +E+ K RN EI T + +I+ +K +P++ +R L + HW ++ + E+ TL I++ + +H E I E++ A E+ I A++ + +V Y D ++ + +E + + DNQ L ++K S + + F+ WE L+ + E ++ + +QR+W+YLE IF + LP E + F +V+ ++++IM +N++N L G+ + L M L+ QK+L+ YLE KR +FPRFYF+ +DDLLEILGQS NP+ ++ HLKK F I + K + M S DGE ++ + V + VE+WLG++ M+ TL D L LR N+ + + ++ Q++ + I +TA +C +E ++ + +KK V LN Y+ A + + T I+ LK+ +L+ +H D++++L V ++WL QLRFY + CVI+ + +F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC EG+D KSMGR++ GL + G+WGCFDEFNR+ VLS V+ QI I + + +N+ + IFIT+NP GY GR +LP+NLK +FRP+AM PD+ LIAE+IL +GF N K L +K+ +++L+ + L+ Q HYD+GLRAL ++L+ A K + Q + T E V ++ ++R ++KLT D F ++++D+FPNI++ I+Y L +E+ I++ + S K+ ++YE R +IVG +GSGK+ W++L+ +L+ + + V+ + +NPKA+ +L G D+ T EW+DG+L+ R + + + WI+ DG +D WIE++NSV+DDN++LT+ +GERI V+ +FE DL+ ASPAT+SR GM++ K V SWL+K+ + + L + K L + + E++ TS + +Y+ L+ + N A F +I + +++E R+ ++ E+ + P NK V Y+ + K ++ + + KI+ P T D R +Y L ++ Q P +L GP G GK+ + Q L S Q V ++ SAQTT +V + + T VY P + +I ++ D+N+P D +G+ + ++ I Y +YD + + + + GR+ +S R S + ++++P+K Q+ I+ + L+ + PI + ++ L + NT+++ + +K HYLF D+++ +LR + ++++ L I +E R+F DRLV + + GI+ + + S D+ F + + K LT LK ++ L +Y S + ++LF+E +++ ++ RV+ +P G++LL G G GR++ + L S + + ++ + Y ++F++D+K + AGVE + + D Q + +LE IN++L+SGEVP LY +E E I + D A ES SL Y +R+++ LHI+L + F + PA ++ W +W ++++L++ + I + G+Q + + +T ++ Y L+L + T Y+ + Y ++ +K+ E+ + N ++ G+ KI E AK+ VAE + + E ++ +++ EAD+ K +T A K +E++ + +N A D E AL P +++A A+ + D+ EI++ PP + +++ V+++ G + +W + LG++ + + FD I+ + ++++ C + F P R S+AA L WV+A Y + P N L + + + ++ + +V + + +K +++ A +L + + + A LV L E RW + + L +L L LLAAA + YM + R E + Q+W+ K F + FL + +W +GL SD S EN +++ +G +IDP + A W+KN + L+I++ Q S++ +LE ++ FG +++Q V + L+P L P+L + G R ++++GDK ++YN +F+ ++ T+ P P+ A + VNF + GL+ QLL + ++ +P+LEE+K +L+ K +L ++E+ +L+ L ATG++L++ L+ +L+ +K ++ +++ LE S +++ D R+A+ P A+ S LFFV++D+ I+ MY+FSL +++ LF +++ S S R L VY Y CR++F+ +L+F+ HM C + E+ F G + + + W+ DA D + L + + S D WH + ++ E+ +P +N + Q++LI+++LR DR+ ++ F L + + P +N+ + E T P++ I+SPG DP+ L +L+ + ++R++ +++GQGQA I LL + G W+ L N HL SW+P L+K + L+ PH FRLW+++ PH F +LQ S+K+T E P G+K N+ R Y SE S+ + LFSL +FH+++ ER+ F+ GW Y F+ +D +L + + W + L +GG V + +D R+L++YI YF D ++ + ++ +P S Y I+ L + P F N D +SQ + + L LQ + T+ +RE K+L + +K +P+ + T SP VV +++RYN+ L++ + SL L K ++G +++ ++ + C+ P +W + + + + R L ++ + E WA + I L P FL A+ Q +AR +S+D L + V SN+ K V + L++EG +D C ++ + L+ + + S M S P YY R V ID+ + D WI+ G AL +
Sbjct: 1013 VLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEF--KGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGL-------FRRLTKLAKEY------KDRNWEIIETT---RSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMD--QHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEE---VFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVK--EWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEA---IRGNLTKIMR-LKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNP---GYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGK-------KRRLQPDLTDEEV---------LLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITS-LCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI-EGSFP--NKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVP---TVDTVR-YNYLVSSLVAN-QNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESR---VEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKM------HYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWI--HECFRVFSDRLVDAADTEAFMGIISDKL---------GSFFDLTFHHLCPSKRPPIFGDFLKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESS--DSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCL--IGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRH---NYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVT-----ANSEKIAVEEIKCQALADN-------AQKDLEEAL--PALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN-EPTWAEAKRQLGEQNFIKSLINFDKDNISDKV---LKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHM--CAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRD--WHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDST-PRSPLVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEET-PWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP-QITPTRAGGQ--TREE-------KVLELAAD-VKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT--LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQFELWASRARP----PVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRK--NSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLM 4423
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Human
Match: DNAH2 (dynein axonemal heavy chain 2 [Source:HGNC Symbol;Acc:HGNC:2948]) HSP 1 Score: 1213.36 bits (3138), Expect = 0.000e+0 Identity = 962/3538 (27.19%), Postives = 1707/3538 (48.25%), Query Frame = 3
Query: 2787 ITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLR----TVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNL---------EKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWS-------QFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIF----GKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNK-----DIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLR-MSNQSNYGINADKYPSQILCLSEMIHFTA---RC----EELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQT-------VKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDW-------IAKRNEFTISTSNVGTVYNGLSNLKAIKNKAH-----------FSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQ--VTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPK-HPIWSQNSKVKL-LANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTS-EYLKDTIDRGLLQY--SRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLAN-----ESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSY----FLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISE--------------AKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRC-KDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKM-QLWMEK------TGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF--TGTFISDKSDRNITVPKWI-DA--DRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLK---PHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANA-LFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQ---LPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTD-------SP--VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNV--SAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYY------DILRDKIVTKIDIPCQSGQQDKWIQSGVALFL 12986
+ ++C+ +K S+ + LR+ G + + YL + + +S+ PQ ++E+ + D + + +QI + +L V ++ + L +W F+ + + M+++ E KT ++ F++ + ++ G + G A Q EE ++ NL KD ++ + E + + EI +D ++N W Q E +T L FR L +E+ K RN EI T + +I+ +K +P++ +R L + HW ++ + E+ TL I++ + +H E I E++ A E+ I A++ + +V Y D ++ + +E + + DNQ L ++K S + + F+ WE L+ + E ++ + +QR+W+YLE IF + LP E + F +V+ ++++IM +N++N L G+ + L M L+ QK+L+ YLE KR +FPRFYF+ +DDLLEILGQS NP+ ++ HLKK F I + K + M S DGE ++ + V + VE+WLG++ M+ TL D L LR N+ + + ++ Q++ + I +TA +C +E ++ + +KK V LN Y+ A + + T I+ LK+ +L+ +H D++++L V ++WL QLRFY + CVI+ + +F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC EG+D KSMGR++ GL + G+WGCFDEFNR+ VLS V+ QI I + + +N+ + IFIT+NP GY GR +LP+NLK +FRP+AM PD+ LIAE+IL +GF N K L +K+ +++L+ + L+ Q HYD+GLRAL ++L+ A K + Q + T E V ++ ++R ++KLT D F ++++D+FPNI++ I+Y L +E+ I++ + S K+ ++YE R +IVG +GSGK+ W++L+ +L+ + + V+ + +NPKA+ +L G D+ T EW+DG+L+ R + + + WI+ DG +D WIE++NSV+DDN++LT+ +GERI V+ +FE DL+ ASPAT+SR GM++ K V SWL+K+ + + L + K L + + E++ TS + +Y+ L+ + N A F +I + +++E R+ ++ E+ + P NK V Y+ + K ++ + + KI+ P T D R +Y L ++ Q P +L GP G GK+ + Q L S Q V ++ SAQTT +V + + T VY P + +I ++ D+N+P D +G+ + ++ I Y +YD + + + + GR+ +S R S + ++++P+K Q+ I+ + L+ + PI + ++ L + NT+++ + +K HYLF D+++ +LR + ++++ L I +E R+F DRLV + + GI+ + + S D+ F + + K LT LK ++ L +Y S + ++LF+E +++ ++ RV+ +P G++LL G G GR++ + L S + + ++ + Y ++F++D+K + AGVE + + D Q + +LE IN++L+SGEVP LY +E E I + D A ES SL Y +R+++ LHI+L + F + PA ++ W +W ++++L++ + I + G+Q + + +T ++ Y L+L + T Y+ + Y ++ +K+ E+ + N ++ G+ KI E AK+ VAE + + E ++ +++ EAD+ K +T A K +E++ + +N A D E AL P +++A A+ + D+ EI++ PP + +++ V+++ G + +W + LG++ + + FD I+ + ++++ C + F P R S+AA L WV+A Y + P N L + + + ++ + +V + + +K +++ A +L + + + A LV L E RW + + L +L L LLAAA + YM + R E + Q+W+ K F + FL + +W +GL SD S EN +++ +G +IDP + A W+KN + L+I++ Q S++ +LE ++ FG +++Q V + L+P L P+L + G R ++++GDK ++YN +F+ ++ T+ P P+ A + VNF + GL+ QLL + ++ +P+LEE+K +L+ K +L ++E+ +L+ L ATG++L++ L+ +L+ +K ++ +++ LE S +++ D R+A+ P A+ S LFFV++D+ I+ MY+FSL +++ LF +++ S S R L VY Y CR++F+ +L+F+ HM C + E+ F G + + + W+ DA D + L + + S D WH + ++ E+ +P +N + Q++LI+++LR DR+ ++ F L + + P +N+ + E T P++ I+SPG DP+ L +L+ + ++R++ +++GQGQA I LL + G W+ L N HL SW+P L+K + L+ PH FRLW+++ PH F +LQ S+K+T E P G+K N+ R Y SE S+ + LFSL +FH+++ ER+ F+ GW Y F+ +D +L + + W + L +GG V + +D R+L++YI YF D ++ + ++ +P S Y I+ L + P F N D +SQ + + L LQ + T+ +RE K+L + +K +P+ + T SP VV +++RYN+ L++ + SL L K ++G +++ ++ + C+ P +W + + + + R L ++ + E WA + I L P FL A+ Q +AR +S+D L + V SN+ K V + L++EG +D C ++ + L+ + + S M S P YY R V ID+ + D WI+ G AL +
Sbjct: 1013 VLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEF--KGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGL-------FRRLTKLAKEY------KDRNWEIIETT---RSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMD--QHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEE---VFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVK--EWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEA---IRGNLTKIMR-LKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNP---GYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGK-------KRRLQPDLTDEEV---------LLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITS-LCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI-EGSFP--NKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVP---TVDTVR-YNYLVSSLVAN-QNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESR---VEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKM------HYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWI--HECFRVFSDRLVDAADTEAFMGIISDKL---------GSFFDLTFHHLCPSKRPPIFGDFLKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESS--DSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCL--IGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRH---NYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVT-----ANSEKIAVEEIKCQALADN-------AQKDLEEAL--PALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN-EPTWAEAKRQLGEQNFIKSLINFDKDNISDKV---LKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHM--CAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRD--WHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDST-PRSPLVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEET-PWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP-QITPTRAGGQ--TREE-------KVLELAAD-VKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT--LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQFELWASRARP----PVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRK--NSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLM 4423
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Human
Match: DNAH6 (dynein axonemal heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:2951]) HSP 1 Score: 1204.5 bits (3115), Expect = 0.000e+0 Identity = 895/3263 (27.43%), Postives = 1580/3263 (48.42%), Query Frame = 3
Query: 3378 EHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKE-----DWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFR-----LLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLL---STMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDF------------------NKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFT---ARCEELLNENNIITLKKELVKKLNI-YTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLAL---------NKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWL----KKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTIS---TSNVGTVYNGLSNLKAIKNKAH---------------FSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEM---NKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQ---VTTLHCSAQTTPVHVLQKLNQACIIINSNTGR----VYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSN-LEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVD-----DYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTI--HSEWSVEVQDSLNDVW----FVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANE----SGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAK---PKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEK----LTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKT-GLE-----KFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLM--FALHMSHCCRPDLFKPQEWELF-TGTFISDKSDRNITVPKWIDADRTVAISNLASAMP----------------ELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNK--------LSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPH----KD-FRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTR-ANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFN------DSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVI-LQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLK-RSSTDSPVVAFLQ-------------LERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPF-DYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF 12671
++F++E +F LEE+ ++ QL+W F E+ Q K D + + +F+TQ + L + +L+ +++ K+ +P++ +R L HW + + L++ LTLE L+ H+ D EI ++++ +A GE + ++++E F ++ + DS++ + ++ DI + D+ + +L S Y + + W+ +LA ++ L+ QR W+YLE IF + LP E F +VD+ ++ IM VNR L + G+ + ++DQ+Q+C L YLE KR +FPRFYF+ +D+LLEIL Q+ NPQ ++ HL+K F I ++F I+ M S +GE V L + VE WLG + M T+L A+ D + ++++ + +PSQ++ I + C E + N+I LK +K+N NA ++ S +H L +LI VH DI+ +L+ ++V ++W +QLR+Y CV +M +++ Y YEY G P+LV TPLTD+CYL L + + LGG P GPAGTGKTE+ K L Q +VFNC +G+D K MGR F GL + G+W CFDEFNR++ VLS ++ Q+ I++ K+ R + + A FIT+NP GY GR +LPDNLK LFRP AM P+ LIAEVIL S+GF+++K L RK+ ++ L E L+ Q HYD+G+RA+K+VL A +L K + D E+V ++++AL+ + L K D + F +I D+FP + I E +Y L S I +V+ QN+ +K+++ YE + R GV++VGP+G GK+T++++L L N Q VK YV+NPK+I +L G ++ T EW DG++ S R V + E WII DG +D WIE++N+VLDDN++L + + ERI+ P ++ +FE DL ASPAT+SR GM+F+ E V +W+ KK E Q + + + L +I K+ I S V T+ L +L K+ + F C + LGGNL EN ++F ++ D+ P+ N ++ + + + RL + E + + D L+ T D R + L + + +G G GKS++ K++ L+ SAQT+ + II S R + ++R+++++ D+N+P+LD++G+ I L+Q + GFYD N L + + V I+ S + GR+ ++ RF + + PS+ L I+ A L L P VK A++++E ++ +K +VD SHY+F DL++ V +L+ D + + + + +E R+F DRL++++ + IL H +++++ LN F+ +G+ + P K T+ L+D +D L +E + ++ F++ ++V+++ R++ + G+ LL G G G+++ + L +H+ K + ++ RGY F DL+ + AGVE +++V L D Q + ++LE IN++L SGEVP L+ +ELE +L + + A E G+R + YF +++ LHI+L M F C+ P+ C++ W QW R+++L + +++ + G++ + L+ S Y+ +L ++T Y+ I +Y+ + +K+ +I + ++ ++ G+ K+ E +V ++K + +L K + + ++K+ + A + + +++ VK E I + +D+ L P + A A+ + +D+SEIR PPD++ ++E + +++ W S + LG + + +D I + ++++ + F P+ ++ S A + WV+A YS ++ + P + + L+ +++ + + V+ + + +++K + L + + A L LE+E RW + I + E+S +T +AAA V Y + R+ ++ W++ LE F + L E +W +GL D +S EN +++ QG P +IDP A W++N L+I+ DSNF +LE S+R G ++++E+ + L+P L P+L + G R +++LGD IDY+ +F+ ++ T+ P P P+ V+ +NFT TK+GL+ QLL+ ++ KP+LEE++ L+ K +L +EE +L+ L + GNIL+N++L+ +L +K +S I LEE+ + ++ R+ + P+A GS ++FVI+ LS+I+ MY++SL F +LF + TS + + R L+ Y V R +F+ +L+ F L + + EW F G+ +K W+ A +L + P L S + W ++K ++ + Q + LS F K+++I+ + +++ AL+ F + L + + ++L +Y+ + N P++ I+S G+DP Q + + SER +++GQGQ I ++ ++G+W+ L+N HL SW+ +E+ + + KD FRL++++ P F +LQ+S+K+T E P G++ N+ R++ + F + G + +F + +FHAIIQER+ F P GW YEF+ +D L K+ I W + + +GGRV + +D R L + +KR+F+ D + SG ++ P A S +++ I L + P F + +N + Q +S +I L + R S G D +I+ + + ++ +P+ L+ +++S V LQ ++R+N+ L+K +H+SL +L+K + G ++++E++ + L Q P +W +P +++ LIL+ V+ W + + + F P FL Q AR + +DEL F
Sbjct: 867 KNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVP---QLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEI-------QDISGQASGEAALEAILKKVEDSWKTTEFVILPHRDSKD--VFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKC---LEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAG--HPSQVILTVSQIMWCRDLTECLETEHSNHIQALKN--FEKVNFERLNALAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNP---GYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSL--------KRENPDLNEDV--------VLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDD-NPDARLPNSGDLWSIHMDFDTKRLDPW----ERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLA--VKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQE-------IIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTII-SACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPP---------AVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREE--IQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEK-----TANVLQDYLDDYNLTNPKEVK---LVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQV--DAGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRY---YTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEAL----PALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNA-KPDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYIN--NPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMS-CNTPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKEG--KIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYSESGIYFA----PMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSSTGGEGKSND-------------EIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNN--LLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYW-----ISGFFFPQGFLTGTLQNHARKYNLPIDELSF 4018
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Celegans
Match: che-3 (Cytoplasmic dynein 2 heavy chain 1 [Source:UniProtKB/Swiss-Prot;Acc:Q19542]) HSP 1 Score: 2952.54 bits (7653), Expect = 0.000e+0 Identity = 1713/4317 (39.68%), Postives = 2631/4317 (60.95%), Query Frame = 3
Query: 99 SKIEDQRKDTIFLITKSHFPNQN---SKFVNEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNA--LVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDTDPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHR---ERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRL-FQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTL-PWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRN-AEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLN-ENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSR-HYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGL-EKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSY---DNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGN--FYGKIQLPSAASKRDYLAIINQ-LSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLK 12989
S +DQRK T FL S+ N K + E L+ F D+ + N+LV + K SN++ ++ N +VF KT + DN S + V + + +QN++G L + ++ ++ELE L + + + G S+ DEI W ++D NE LQ + E M+ + + L+E E+ +++W T YPQ+RMK L+E A+ L I +++ W + V + L AI+VC + + L + WK+ + H W D + + +++ F+ RL EI SL+++ Q+ ++L R E E IE A + + PLAYNP+TEP WK + R IE I L ++ + A A Q + L ++ + R I L ERE L +LV Q ++F +S Q + ++ ++IVW +Q +++ I S++ +L ++ + F + F+E++ +E F+ W +E T L D+ N+ I L+ G++M L + L VNYSDRL+ L++EVR L LG++I +++ A+NG+K+Y VILKQ+A FYNTI+ QMIP QQ++ML+ AI FEKLV S + + V WN+P++L +FI +LQ A + ++NR LR H + E + LM +++++Q +WK+ + +IR + + E +N + PW H D QLYKAL QY G+E++ L I V LV+ ++Q PT EEI+SKY+KE+ +F+ +P++F+G+ + + + +IER+ Y+KAE L ++ C F +W+++ +DLEE ++++ D+E FK +K K +EAE+LP+E+K +CI V+ A +K +++ IQ ++DAL +LR +I T S+ +L+ +I++L+ PQ+IDEIAEA H F ++ R++ + E+ LLR+VAG G++ + L+Q WD+FELM++ Q M+++Q+EV+K+N+ + K + + K RW+ KP D L G + L A+Q IK+K+++ ++L + +EK+C F +EP + +++EI +DI Q + W +E + L +++E+W+ FRS+ YLF+EFL +W EKL+ T M++RL K+++ +K++ LK+ RG+ LS DHW EMFR L +PRG T+E L +L + II + + +K+LN +AQGEV IR+AI+EL LW A F L +Y S ++ +IKEW++ I+ + D+Q LLQSLK SPYY F DK AVWE +LADLD +L +N+IQRKW+YLEPIFG+ ALP E SRF RVD ++R+I++DV+++ R++SLCS +K L ++DQL RCQKALN++LE+KR+ FPRFYFIGDDDLLEILGQSTNPQVI++H+KKLFQGI V F+ + II+M S +GE V L V I +VE+WL L++EM+ TL D + A+ D + S KYPSQ+LCL+E + F+A E LN +++ + K +L++KL YTN K+ V DLKLKSLILD +H+ID++DQLL +S+ W W +QLRFY + G V++ V +EF YTYEYQGN KLVHTPLTDKCYLTLTQ M+MGLGGNPYGPAGTGKTESVKAL +L GRQVLVFNCDEGIDV SMGRIF G+V+CG+WGCFDEFNRL+ VLSAVSMQIQ IQ IK++ T + V V+ NSAIF+TLNPAGKGYGGRQK+PDNLKQLFR V M +PDN+LI+ IL S+GF +A L RK+V++F LSR++L+ QQHYDWGLRALK VL G L +TQ N ET L+VQAL +NTLSKLT++D F SLI D+F N+ + +++ L + +E + Q +K+ ++YEQ+RQR+GVV+VG +GSGKSTIWK+L+ +L + +K NPKA+ R++LLG++D+DTREWSDG++T +AR+V K+ + WI+CDGDIDPEW+E+LNSVLDDNRLLTMPSGERIQFG NVNF+FET L ASPAT+SRMGMI++S E K +V SWL K E + +++++ F++ L W+ R+ ++ + NGL++LKA K K F V L G + +R+ FA V M+ + N ++E+ + +++Y+ + + ++ +++ +++ L P + TAD QR D WL S ++ F+++G GCGK +L HCFQ Q+ +L+CSAQ++ H+LQ + Q C+ ++ TGRV+RPK+ +IL+LK INLP DK+GT++L++ LQQ++TY+GF+D NLE+V ++ +Q V SMN S+S R S++R S++ QL IY YL P+L+ + +NS++ +AN M+++Y++++S F D +LF+P DLT WV+SLLR++L L ++ +E+ RIF DRL + + + + + IL N I + E V +VT G+ P + P+ ++ ++ L +I+R ++ E + + L ++ A +DRVLT PGG + L G+ G GRR + LV+HMHNI++ SP + + KQF N+LK+ + A EH+VL+LEDHQ + +L+ INSLLASG VPGL+T +EL+ ++ + + AN++ G+L + A RI+ +H++LI++ +F IN NPA K+C+V + +++ R+S+++IP KI E +T +D + + F D+ P S Y F++ + ++ K+ + R ++ G+ K++EA++ VA+++ KA ++SKLL EKQ EAD+ALK IT M GA ++K ME+L T +ENV + ++KA ID++L ++P + +AR AV IKS LSEIR+LRAPP+ +RDIL+ VLL MG +DTSW +MR FL K G++++I FDA RIT E +V L+ + +SF+ NAKRAS AAAPLAAWVKAN++YS LEKIAPLE E+N+L +NL+ AEK+M++L KG+ VD+ V ++ FE +A +++ +L +TI A LV L EFERW QI E S + + SL+ +A + Y+ E RK ++ + + F F + E EQL WK +GL +D+LS+EN ++ P +ID S + +L + K E + T +EL++RFGKT+II ++ + L P+LR DL SQGPRQV+ G K ID+NPDFK++ TR+ + + P++ ++ VNFTTT + L QLL + + KP+LEER ++LL++ E K+EL +E+ LLQ+LA++ GN+L N LL SLNK+KES+ I++S+ ES +L L ++D ++PL+ SSLFF S+L N MY +S+ + + LF + + + E S+ R +L ++ V+ ++ R IF+ DRLMFA+ + P +F+P+EWELFTG + + +D + +WI DR +++ + + +P L++ I+DD W++F+K+ +CE P++++ K++ FQK+L IQA++P+RL + L F L + ++P + L I++ E+ S EPIL I++ GADPSQ+L E ++ + + Y+ ++MGQGQ + + + G+WLCL NLHL+ +P + K L+ PH++FRLW+T E F +++LQ SLKIT+E PPGV+NNLLR+Y D +++ I+ ++F LAW HA++QERR FIPQGWTKFYEF +D+R ++Q+ + W+F+ G+ + I+GGR++N FD +VL SY+ F D +NG I L + + ++Y+ I++ + + P F LP+NI S Q + + + I +R L ++ TK S +++ +++ WK L Q ++ K LP +++ + P+ L LE N++ L+K +H S+ ++K +K L + VQ + L+ QTP+ W W GP +P DY+ +++ K + + E S+ LLS+ +D +LF+P+ FLNALRQ T+R IKI +D+L W S + AK V++ L ++G FD + + E S + P V + W ++ +S + I +P+Y R ++ +++PC+ D+W + VALFL+
Sbjct: 3 SDSKDQRK-TYFLRVASYLLGLNIVEEKLKSTEPLEIFLDS-NTNLLVFSRSEQKLELSNKMKSSAPSANVFRVVFYKTQSVPLNNDNFKSVVNVISANGTLNHVFLKSVQNVFGKELTEGNNMQLIAAVNELEESLLATVE---------------MSGGGSLHDEIRSWKGQTGKPAND-----YNEAFKQLQLLVETMEERSIDELSELVECFEDT---CDELWNCGT---PYPQNRMKMLIEYGASYLCETITFKIDDSAIWRNDK--VADQLRSAIDVCDQMLIIVRLLTAQTWKRNVEHTWEGDA-MEMKFLNGFKDRLDEILSLKSLGGQLEELLEERGVREETEKTIETAMR---GMAPLAYNPFTEPNWKSRLLVSERSIE---GTIDRTLPILKQRLAPANGDSQSIVLSLEKLKSFLCRSNIKEKLQHEREMFLNRLVSMLSQKNQEFNEKSLQVDAKNFQFLTEVAARIVWIRQQTSQMESIRSLSKMMLNNISNYSAFASKLDEFIEKLQYAEKECFDDWCRE-TVGLIDNKNETINLETTGKIMYLEASNRELNVNYSDRLLRLLKEVRQLISLGFNIPSKIMSCANNGEKYYRFGVILKQIAHFYNTIDQQMIPSQQSLMLEEAIAFEKLVIPRKDASNSASKVTWNDPKQLEEFIVQLQSAEQKLSNRNRRLRNVHMELIEMVEKLMDLNIVKQNNEWKEIILKIRSKMKEEEIVHGAVKNNMKPWLIHWDFQLYKALLIQYEWGIESIQSQLSTISVSLVFADQKIQLRPTIEEIRSKYYKELCRFLRIPDKFRGVQEDENSTKF-YAQMIERSMHLLPTVYEKAEQLMMKVETCDAIFVDWLVISQVDLEELIEENLKTAADWESQFKILKGKAREAERLPHELKFECILVSTAGVKSAIEDAIQRLYDALSWTLRHSISTTSQSISTFLSQAIEVLNTVPQSIDEIAEANAKHVIFAENNRRLKEEWKVMEEQLTLLRSVAGTGMEQIDNLEQTWDRFELMLDGHQSMIKDQVEVLKSNVETSVKGMKDEAEKLKARWEQFKPRNDALQ-GDREEMLKAIQFIKEKRVQWQQLSDGREKIEKECGQFGLEPPKMDIIDEIDEDIKQFEDNWLIYEMFNNELDTMSQEEWIVFRSKTYLFDEFLQKWMEKLKGTGSQTHMSVRLMKDVEHFKEVSSALKFCRGDVLSADHWHEMFRFLGLPRGTTIEKLKFADLLSVSKNIIENTDQLKQLNSRAQGEVAIRDAIQELTLWAAQTEFTLADYKHSNGQNLKIIKEWKESINSLKDSQALLQSLKSSPYYSQFTDKTAVWETRLADLDVFLAQMNEIQRKWIYLEPIFGRGALPSEASRFSRVDSEYRAILNDVSKDARLVSLCSRQSLKKSLEQIVDQLNRCQKALNQFLEQKRTAFPRFYFIGDDDLLEILGQSTNPQVIQTHMKKLFQGINRVQFSSTGETIISMVSSEGETVPLSKAVRIVPQVESWLQELSDEMRRTLKDLTAQAVADAQPS--------LAKYPSQVLCLAEEVKFSASIENNLNGSSDLNSFKSQLLEKLKAYTNMKVDDK------VSDLKLKSLILDLIHHIDVVDQLLTNQAKSINSWTWQRQLRFYL--VNGGIVLRQVSSEFEYTYEYQGNYAKLVHTPLTDKCYLTLTQAMYMGLGGNPYGPAGTGKTESVKALAALMGRQVLVFNCDEGIDVTSMGRIFTGIVECGAWGCFDEFNRLDSTVLSAVSMQIQTIQGAIKSRAGSCTFGGKNVQVNPNSAIFVTLNPAGKGYGGRQKMPDNLKQLFRAVVMGKPDNELISSTILYSEGFVDATALARKIVSVFQLSRQMLSKQQHYDWGLRALKVVLGGCGAL-------RRTQTNKN---------ETDLVVQALLLNTLSKLTFSDSERFNSLIDDIFSNVTKEMTKFEELVEPLGVAAQEMGIKLGDKQMEKVFQLYEQMRQRIGVVVVGAAGSGKSTIWKILQRSLILTKKPLKVTQFNPKAVNRSKLLGNMDMDTREWSDGIITMAAREVTKDTS-VHHWIVCDGDIDPEWVEALNSVLDDNRLLTMPSGERIQFGSNVNFLFETDSLQFASPATVSRMGMIYISEEDVTPKDIVASWLVKTTEDLHADMPSWIEEHFWRCLKWV--RSHKISGITSFAILKNGLTHLKASKTKTQFLVLLFNGFLPTVTPENRQEFAKGVV------FQGMSVPDPKNICYDERIDGIMSYTDDVSQNVTKEEV--EREDLRPFVQTADTQRYSDIIGSWLQSGNRESFLITGTTGCGKQQLLKHCFQNDPESQLASLYCSAQSSSSHLLQLIQQNCVQASNPTGRVWRPKDRPNMILFLKGINLPAPDKYGTNELLALLQQLLTYQGFFDHNLEWVSIENIQFVGSMNPIGDGAAVSISNRLFSLLRCVSLNTTDSSQLTSIYRTYLTPILEE------VGERNSEI--IANRMVDIYNKVQSNFRPTDSVVFLFSPRDLTNWVVSLLRHEL------DQGKLEAVICFEARRIFADRLPTENDKLKFEEILRNVIPISQANETVIFKEKV-YVTTGTVVPGESNTGLPLTPINMSDF-NQLLAKSINR----FAFEIANFNCPLTSQLAFFCACIDRVLTGPGGHLFLPGRPGFGRRDSVRLVAHMHNIQVFSPPVTANFSAKQFDNELKNAITQAVTNNEHVVLILEDHQLRKNIFLQAINSLLASGNVPGLFTQQELDGLVALVSEAANQASFTGALQQFLAHRIRSLVHVVLILEVEANDFKINITENPAILKHCNVIFADRFDRNSLVEIP-----KIQMESQG------------ITTTDAILTGFNDVLVNLPEHLSIQPIKYRQFVENFFQLLGYKRLTLSVRLERLKGGVSKLNEARDEVAKMQKKAGKKSKLLAEKQAEADEALKAITESMSGAEDQKLSMEQLKAATEKENVRIEEQKAKIDEQLKEVQPLIDEARRAVGSIKSESLSEIRSLRAPPEAVRDILQAVLLFMGILDTSWEAMRKFLSKSGVKDDIMNFDANRITNEIHKKVTALVKQKSNSFEEANAKRASAAAAPLAAWVKANLEYSKILEKIAPLEGEKNKLVKNLKKAEKQMENLSKGLQSVDEVVGELKRKFEVLMKEATQIKVDLDREQDTIRIAGTLVESLSGEFERWKIQIETFGEEQSKMELCSLITSAFITYLGGCSEKDRKSLLKSMCKMFNMPPTFKPLSFASLETEQLNWKTKGLPADQLSLENGSILFTSCHAPLIIDRSGQVSLFLSKFLE--KSETFKAAQPDLMTQIELAIRFGKTIIIDDIVEFDSALIPILRKDLSSQGPRQVISFGGKSIDFNPDFKIYFCTRDEKVDIRPNSYVQLNIVNFTTTISALSAQLLDVAIHLEKPELEERSSSLLRDAELKKLELEGLEQLLLQQLASSQGNLLENTALLDSLNKSKESAEIITKSIVESEQLHKELTTQKDIYVPLSLFTSSLFFSFSNLQFHNPMYNYSVNTIMHLFGKTIKSCE--DKSSTRVETLARQMQLTVFYHISRGIFRQDRLMFAVAFINATMPKMFQPKEWELFTGVLVDESTDLSALRVQWISPDRLQSLARIRTHLPSLFNNFQIQDDATWNEFSKTLQCENAFPKNVELKMTHFQKVLFIQAVKPERLYNCLMDFVLKTLNIPSINPPAFELKHIFQ-ESESTEPILFILADGADPSQELSEFASSM--NVPYHSISMGQGQEIAAYEAIRESASKGEWLCLNNLHLMLQAVPSIFKHLSLTTPHENFRLWLTTEGDARFPSMMLQQSLKITFEPPPGVRNNLLRTYTQIDRSTKNVIT-------CQSIFVLAWLHALLQERRTFIPQGWTKFYEFGASDVRVAKSFVEQL---TANKADWEFVRGILKFVIYGGRIENDFDFKVLDSYLNVLFCDEKINGRAGSQLVKGIDLLATTNVQEYIGHISKSVPSVDEPYLFGLPENIKYSWQIVEADRTISSIRTL---ALGDTKNALSDQSDKISQIVSLWKKLCQSDDLPKRELPTAIRSA---DPISEVLCLETINALSLIKQLHRSIGHVAKSMKTPSLASPAVQKTIQSLVFQQTPDEWDSMWAGPSDPADYLNVVVKKTRGTLQLFESSKSSSLLSSPIDFSDLFYPNIFLNALRQTTSRQIKIPLDQLILSSAWTPSQLPAKQCVQVQGLLLQGATFD-SFLRETTVSSAAYSQAPIVFLAWT--SESSSTITGEQIQVPVYSSSERSDLICSVNMPCRGA--DQWNIAAVALFLR 4171
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Celegans
Match: dhc-1 (Dynein heavy chain, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q19020]) HSP 1 Score: 718.383 bits (1853), Expect = 0.000e+0 Identity = 521/2030 (25.67%), Postives = 1010/2030 (49.75%), Query Frame = 3
Query: 6894 LILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKE-SERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY-DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEW--SVEVQDSLN-DVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIP-----YMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCP------------VEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMG-TMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEK---TGLE-KFDMRK--FLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEIS--TDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHC-CRPDLFKP---QEWELFTGT--FISDKSDRNITVPKWID-----ADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIP---QSLKNKLS----LFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSS-MNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQG----QADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILD---QIIKKSNRNIQ-----WKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFN------DSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQ-LRILQR---FSVHGTKFDKDIWSRELNPVLNRW-KILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEE--PFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGC 12746
++ T D R+ WL +P +L GP G GK++ L + + ++V ++ S+ TTP +L+ + C + G V P + S+ L+++ +INLP DK+GT ++ISFL+Q++ GFY S+ +V L+ +Q V + N + GR +++RF V + + YP + L IY + + +LK + Q L N M++VY + FT DD HY+++P +LT+WV + P+ S +A L+ + ++E++R+FQDRLV+ + R+ D ++ T + + + ++L + + W SR +T E L+D + L + E D+ ++LF ++ D+V ++DR+ + G +LL G +G G+ T S V+ ++ + + K+H Y F D+++ L+ AG E + ++++ L+ +LE +N+LLA+GEVPGL+ +E ++ +K+ A G L +F ++ LH++ M+ S ++PA F C + W WS +++ ++ M +++ E +LT + +Q T D + + +H T V T RH+++FIK ++ ++ +K++++E + H+ +G+ KISE +E V EL+ +S L EK+ A+ LK++ Q A E K E+L + E+ +A++K ++++LA +EP V +A+ AV IK S L E++++ +PP ++ LE + +++G + T W ++R + K I FD +T E Q+E+ + FD N RAS+A P+ W +A + YS L K+ PL NE +L++ ++ K ++ ++++++++ Y++++ + A ++ +L + E ++ + +L+ L +E +RW+ + ++ +L +LL++A + Y + R E W GL + D+ + +L+T ++L+W+ L D+L ENA+++ + P +IDPS A ++ F + ++ + D +F LE ++RFG +L++Q+V+ +P+L P+L ++ G R ++ +GD+ ID +P F++F+ TR+ + PD + V+ VNFT T + L Q L ++ +P +++++ +LL+ + + + L +E++LL L + G IL++ ++ +L K K + ++Q E+ K+ +D + L+ S ++ + L++I+ +Y +SL + +F L T E+S TD R + L + V+ V R + +D+++ AL + R + P Q ++L G F++ + + T+P +D +++A + +++ L + + + E +P KLS ++++ ALRPDRL ++ + + + +++ I ++E +EP+L+ + G D S +++L+ + + + +A+G QAD L +++G W+ LKN+HL SWL LEK L+S+KPH FRL++TAE H + +L++S + +E G+K NLLRS + ++K + R+ + W HA++QER + P GW+ YEFS ADLR + LD + + N++ W + L I+GG++DN FD +L ++ F D V+ + + P+ + K + + +L + P++ LP+N ++ ++ L++ F+ G + K W +L + +W ++L + + ++ ++ + P+ F + E +L+K + L +S V + + E + L+ L G+ P W +++ P E D+M L + K + + + D L LG F P+ ++ A RQ A+ S+++L G ++ + + +I + I G
Sbjct: 2510 VVPTIDTVRHEMLLAAWLAE--HKPLVLCGPPGSGKTMTLLAALRSQQEMEVVNVNFSSSTTPELLLRTFDHYCEYRRTPNGVVLAPVQLSQWLVIFCDEINLPAPDKYGTQRVISFLRQLVELNGFYRTSDHSWVSLERIQFVGACNPPTDPGRHPMTSRFLRHVPIVYVDYPGQTSLQQIYGTFNRAMLKMTPAVRGLADQ------LTNAMVDVYLASQEHFTQDDQPHYVYSPRELTRWVRGISEAITPLES-LSAEQLVRLWAHEAIRLFQDRLVTEEEREWTDKLVDTTAERYFGNACRLDEALKRPLLYSCWLSRNYV--------------PVTREELQDYVSARLKGFYEEELDVKLVLFDQMLDHVLRIDRIYRQSQGHLLLIGTAGAGKTTLSRFVAWLNGLSVFQLKVHSKYTAADFDEDMRTVLRRAGCRNEKLCFIMDESNMLDTGFLERLNTLLANGEVPGLFEGDEHTTLMTQIKEGAQRQGLILDSHDELYKWFTQQVMRNLHVVFTMNPSGSGLRERASTSPALFNRCVLNWFGDWSENALYQVGSELTRTMDLDRTDYEGSVRLTPSCELVPSQPTYRDAVVNTLCLVHKTVQKFNEMETKKGHRVMACTPRHFLDFIKQFMSLFHEKRSDLEEEKIHLNIGLNKISETEEQVKELQKSLKLKSNELQEKKEAANLKLKEMLGDQQKAEEEKKFSEQLQKELAEQLKQMAEKKTFVENDLAQVEPAVAEAQTAVQGIKKSQLVEVKSMSSPPVTVKLTLEAICILLGENVGTDWKAIRQVMMKDDFMTRILQFDTELLTPEILKQMEKYIQNPDWEFDKVN--RASVACGPMVKWARAQLLYSTMLHKVEPLRNELKRLEQEAAKKTQEGKVVDVRITELEESIGKYKEEYAQLIGQAENIKQDLLSVQEKVNRSTELLSSLRSERDRWSSGSAGFSQQMDSLVGDALLSSAFLAYAGYYDQMLRDEIFHKWFNHVVNAGLHFRHDLARIEYLSTVDDRLQWQLNSLPVDDLCTENAIMLHRFNRYPLIIDPSGQAVEYIMKQFAGKNIQKTSFLDESFRKNLESALRFGNSLLVQDVEAYDPILNPVLNREVKRAGGRVLITIGDQDIDLSPSFQIFMITRDSTVEFSPDICSRVTFVNFTVTSSSLASQCLNQVLRSERPDVDKKRNDLLKLQGEFAVRLRHLEKALLAALNESKGKILDDNSVIETLEKLKNEAAEVAQKSAETDKVMAEVDAVSAQYQRLSTACSHIYHTLQQLNEIHFLYHYSLDFLVEIFTHVLKTPELSSTTDYAKRLRIITTSLFQTVFRRVSRGMLHTDKVLLALLLMRIHIRSNPSAPAYEQHFDLLLGRSDFVAKNDEADSTIPGGLDFLTVENKKSIAKARKVVGFENVFAHLQ-HNSAAVTSWLTNDNPESNVPVVWDDADGKLSPLCIAMNSLIVVHALRPDRLMASAHRVVSTAFDDHFMQQDKVVDILSIVDNEVSPSEPVLLCSATGYDASGKIEDLAVET--NRQLTSIAIGSAEGFNQADSALG---TATKSGRWVLLKNVHLAPSWLAQLEKRLHSMKPHAQFRLFLTAEIHPKLPSSILRASRVVVFEPATGLKANLLRSLSSIPPQRLTKAPT-ERSRLYLLVCWLHALVQERLRYTPLGWSTAYEFSDADLRVACDTLDAAVDAVAQGRPNVEPERLPWTTLRTLLSQCIYGGKIDNQFDQVLLDCVLENLFTAKSFEQDHVLIPKYDGDDSLFTPNMSKKDQMIGWVEELKNEQLPAWLGLPNNAEKVLLTKRGESMLRNMLKVTDEELAFNEDGKEEVKPQWMAQLGELAKQWLQLLPKEIVKMRRTV------ENIKDPLFRFFEREVNLGSQLLKDIRRDLNEISAVCRAEKKQNNETRALAASLQKGEVPTGW-KRYTVPREVTVMDWMTDLNERLKQLIR---IGGADNLKRETFWLGGTFSPEAYITATRQQVAQANTWSLEQLNLHIHIGRTDSTDVF--RISGIDIRGA 4495 HSP 2 Score: 694.115 bits (1790), Expect = 0.000e+0 Identity = 404/1072 (37.69%), Postives = 625/1072 (58.30%), Query Frame = 3
Query: 3372 DCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIR----LQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVE--NWLGNLNNEMKTTLSDQLSYALQDL-RMSNQS----NYGINADKYPSQILCLSEMIHFTARCEELLNEN-NIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKD----QGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIK-NKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMV--SLKGQH-----KKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKF-YVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQV---VKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWL 6488
D H E ++ T+ E ++ + +W + TG+ ++ WLS + R + L + +L+ + T + +++ + Y + ++ ++ E L + HW +M + M L LTL + DA +I+RH IK++ AQGE+ + E +RE+ + +LV Y N LIK W D+ +++ ++Q L ++K SPYY+ F++ A W+ KL ++ +QR+WVYLE +F +A LP E SRF + D ++M V + R+L + +M G + LL + D L + QKAL EYLE +RS FPRFYF+GD+DLLEI+G S + I+ HLKK+F GI +D N++ + I S +GE V+L +++ T +V +WL L EMK TL+ QL+ +L +M+ Q+ +Y DK+P+Q++ L+ I + E+ L + +++ +VK L + ++ + + K+++LI + VH D +L+ ++ ++ WL+ +RFY K + CV++M +++F Y +EY G +LV TPLTD+CYLT+TQ +H LGG+P+GPAGTGKTESVKALG GR VLVFNCDE D ++MGRI +GL + G+WGCFDEFNRLEE +LSAVS QIQ IQ+ ++ + L+ +R+NV+ N IFIT+NP GY GR LPDNLKQLFR +AM++PD LIA+V+L S GF+ A+ L K+V +F L +E L+ Q HYD+GLRALK VL A N+ + K+ G+ +E+V E ++++Q++ + KL D SL+ DVFP I + L + V E ++ ++G+ K+L++Y+ G+++VG SGSGK+ WK+L AL + +V++ KA+ + L G +D +TREW+DG+ T R++ V+ + + WII DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV IFE DL A+ AT+SR GM++ S E + L +L
Sbjct: 1275 DSAHAPSEGDKLTVATE---ELAAMKDVWKALQPVYTGIDEAKEKTWLSVQPRK--IRQSLDELMNQLKQLPVKCRTYKSYEHVKQMLHTYGKMNMLVAELKSEALKERHWHQMMK--EMRVNWNLSDLTLGQVWDA--DILRHEHTIKKILLVAQGEMALEEFLREMREYWQNYEVELVNY----QNKTRLIKGWDDLFNKLKEHQNSLSAMKLSPYYKQFEESAQSWDEKLNKINAMFDVWIDVQRRWVYLEGLFSGSAEISTLLPFESSRFATITTDVLALMKKVAASPRILDVVNMQGAQRLLERLADMLAKIQKALGEYLERERSSFPRFYFVGDEDLLEIMGNSKDITRIQKHLKKMFAGITAIDINEEDRSITAFHSREGEKVDLV-KIVSTKDVRINDWLQALEAEMKHTLARQLAASLTHFSKMNIQTMTTDDYVEWLDKFPAQVITLTAEIWWCDEMEKTLADGKGAENVEQAVVKTLELLADSVLKEQPP----IRRKKMEALITELVHKRDTCRKLVSMKIRAANDFGWLQCMRFYFDPKQVDPVRCCVVKMANSQFFYGFEYLGIQERLVRTPLTDRCYLTMTQALHSRLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRILVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQTIQEAVRAGGDMSVDLVGKRLNVNSNIGIFITMNP---GYSGRSNLPDNLKQLFRSLAMTQPDRQLIAQVMLFSQGFRTAETLANKIVPLFILCKEQLSDQCHYDFGLRALKYVLVSAGNI---KRDKLDKMGSAALEDVA----EQQMLIQSVCETLVPKLVNEDIALLFSLLSDVFPGIHYTANQMRELRQQLSTVCDEHLLIYSDVQGEMGSMWLDKVLQLYQITNLNHGLMLVGSSGSGKTMAWKVLLKALERWENVEGVAHVIDAKAMSKDSLYGVMDPNTREWTDGLFTSVIRKIIDNVRGEADRRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSIPPNVRIIFEVADLKYATLATVSRCGMVWFSEEVVTSEMLFERYL 2318 HSP 3 Score: 72.4034 bits (176), Expect = 1.201e-11 Identity = 99/439 (22.55%), Postives = 172/439 (39.18%), Query Frame = 3
Query: 789 YPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLI---------------KRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPH---------RERQEFKIEE-------------AFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIH-RSRQG-KVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVL-----KDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRR---LDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQ 1964
YP R L+E I+ +L + L+ A E ++Q + S W D DK I K WK HK + RL +I R HEQ ++ RER++ I+ A+++ N+ L + P W+ A K++ I ET I TRLK + S+ ++ +F RYN L RP+I + + + L+ ++ +L+ F R QG K+ T +KI+W + E +L + +VL +DG + + NF +++ Q F++W + + + L + R+ + GR M+L L +NY L +EV L +G+ + ++ A + A L + A+ + ++N + Q
Sbjct: 368 YPLQRALRLVEAISRDLNSQLLKVLSSYNLMRTPIAEFNEIMSQCQALFSKWDDEYDKFIALLRDINKKKRDDPSKLSWKVTAVHK-------------RLETRLMQILQFRKQHEQFRTVIERVLRPVGNGSREREQLMIDSSEGEKSPDEQVDIAYEFLKNVDFLDVD---SPAWENAFKRYEDQIGVVETAITTRLK---SQLESSRNSNEMFSIFSRYNALFIRPRIRGAIYEYQTRLINRVKEDINELQARFTKARGEQGVKIMQTVGLPPFSAKIMWIRNYERQLQRYMKRVEDVLGKQWENHVDG-RQLKADGDNFKVKLNT--QPMFDEWVESVQSQNWTLPNKILTVDRVQVDGR-MQLQ-----LKINYHSDSSVLYKEVSHLKSMGFRVPLKIVNWAHQANQMRPSATSLIEAARTFASVNAALASVQ 778
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Celegans
Match: dhc-1 (Dynein heavy chain, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q19020]) HSP 1 Score: 718.383 bits (1853), Expect = 0.000e+0 Identity = 521/2030 (25.67%), Postives = 1010/2030 (49.75%), Query Frame = 3
Query: 6894 LILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKE-SERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY-DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEW--SVEVQDSLN-DVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIP-----YMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCP------------VEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMG-TMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEK---TGLE-KFDMRK--FLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEIS--TDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHC-CRPDLFKP---QEWELFTGT--FISDKSDRNITVPKWID-----ADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIP---QSLKNKLS----LFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSS-MNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQG----QADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILD---QIIKKSNRNIQ-----WKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFN------DSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQ-LRILQR---FSVHGTKFDKDIWSRELNPVLNRW-KILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEE--PFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGC 12746
++ T D R+ WL +P +L GP G GK++ L + + ++V ++ S+ TTP +L+ + C + G V P + S+ L+++ +INLP DK+GT ++ISFL+Q++ GFY S+ +V L+ +Q V + N + GR +++RF V + + YP + L IY + + +LK + Q L N M++VY + FT DD HY+++P +LT+WV + P+ S +A L+ + ++E++R+FQDRLV+ + R+ D ++ T + + + ++L + + W SR +T E L+D + L + E D+ ++LF ++ D+V ++DR+ + G +LL G +G G+ T S V+ ++ + + K+H Y F D+++ L+ AG E + ++++ L+ +LE +N+LLA+GEVPGL+ +E ++ +K+ A G L +F ++ LH++ M+ S ++PA F C + W WS +++ ++ M +++ E +LT + +Q T D + + +H T V T RH+++FIK ++ ++ +K++++E + H+ +G+ KISE +E V EL+ +S L EK+ A+ LK++ Q A E K E+L + E+ +A++K ++++LA +EP V +A+ AV IK S L E++++ +PP ++ LE + +++G + T W ++R + K I FD +T E Q+E+ + FD N RAS+A P+ W +A + YS L K+ PL NE +L++ ++ K ++ ++++++++ Y++++ + A ++ +L + E ++ + +L+ L +E +RW+ + ++ +L +LL++A + Y + R E W GL + D+ + +L+T ++L+W+ L D+L ENA+++ + P +IDPS A ++ F + ++ + D +F LE ++RFG +L++Q+V+ +P+L P+L ++ G R ++ +GD+ ID +P F++F+ TR+ + PD + V+ VNFT T + L Q L ++ +P +++++ +LL+ + + + L +E++LL L + G IL++ ++ +L K K + ++Q E+ K+ +D + L+ S ++ + L++I+ +Y +SL + +F L T E+S TD R + L + V+ V R + +D+++ AL + R + P Q ++L G F++ + + T+P +D +++A + +++ L + + + E +P KLS ++++ ALRPDRL ++ + + + +++ I ++E +EP+L+ + G D S +++L+ + + + +A+G QAD L +++G W+ LKN+HL SWL LEK L+S+KPH FRL++TAE H + +L++S + +E G+K NLLRS + ++K + R+ + W HA++QER + P GW+ YEFS ADLR + LD + + N++ W + L I+GG++DN FD +L ++ F D V+ + + P+ + K + + +L + P++ LP+N ++ ++ L++ F+ G + K W +L + +W ++L + + ++ ++ + P+ F + E +L+K + L +S V + + E + L+ L G+ P W +++ P E D+M L + K + + + D L LG F P+ ++ A RQ A+ S+++L G ++ + + +I + I G
Sbjct: 2510 VVPTIDTVRHEMLLAAWLAE--HKPLVLCGPPGSGKTMTLLAALRSQQEMEVVNVNFSSSTTPELLLRTFDHYCEYRRTPNGVVLAPVQLSQWLVIFCDEINLPAPDKYGTQRVISFLRQLVELNGFYRTSDHSWVSLERIQFVGACNPPTDPGRHPMTSRFLRHVPIVYVDYPGQTSLQQIYGTFNRAMLKMTPAVRGLADQ------LTNAMVDVYLASQEHFTQDDQPHYVYSPRELTRWVRGISEAITPLES-LSAEQLVRLWAHEAIRLFQDRLVTEEEREWTDKLVDTTAERYFGNACRLDEALKRPLLYSCWLSRNYV--------------PVTREELQDYVSARLKGFYEEELDVKLVLFDQMLDHVLRIDRIYRQSQGHLLLIGTAGAGKTTLSRFVAWLNGLSVFQLKVHSKYTAADFDEDMRTVLRRAGCRNEKLCFIMDESNMLDTGFLERLNTLLANGEVPGLFEGDEHTTLMTQIKEGAQRQGLILDSHDELYKWFTQQVMRNLHVVFTMNPSGSGLRERASTSPALFNRCVLNWFGDWSENALYQVGSELTRTMDLDRTDYEGSVRLTPSCELVPSQPTYRDAVVNTLCLVHKTVQKFNEMETKKGHRVMACTPRHFLDFIKQFMSLFHEKRSDLEEEKIHLNIGLNKISETEEQVKELQKSLKLKSNELQEKKEAANLKLKEMLGDQQKAEEEKKFSEQLQKELAEQLKQMAEKKTFVENDLAQVEPAVAEAQTAVQGIKKSQLVEVKSMSSPPVTVKLTLEAICILLGENVGTDWKAIRQVMMKDDFMTRILQFDTELLTPEILKQMEKYIQNPDWEFDKVN--RASVACGPMVKWARAQLLYSTMLHKVEPLRNELKRLEQEAAKKTQEGKVVDVRITELEESIGKYKEEYAQLIGQAENIKQDLLSVQEKVNRSTELLSSLRSERDRWSSGSAGFSQQMDSLVGDALLSSAFLAYAGYYDQMLRDEIFHKWFNHVVNAGLHFRHDLARIEYLSTVDDRLQWQLNSLPVDDLCTENAIMLHRFNRYPLIIDPSGQAVEYIMKQFAGKNIQKTSFLDESFRKNLESALRFGNSLLVQDVEAYDPILNPVLNREVKRAGGRVLITIGDQDIDLSPSFQIFMITRDSTVEFSPDICSRVTFVNFTVTSSSLASQCLNQVLRSERPDVDKKRNDLLKLQGEFAVRLRHLEKALLAALNESKGKILDDNSVIETLEKLKNEAAEVAQKSAETDKVMAEVDAVSAQYQRLSTACSHIYHTLQQLNEIHFLYHYSLDFLVEIFTHVLKTPELSSTTDYAKRLRIITTSLFQTVFRRVSRGMLHTDKVLLALLLMRIHIRSNPSAPAYEQHFDLLLGRSDFVAKNDEADSTIPGGLDFLTVENKKSIAKARKVVGFENVFAHLQ-HNSAAVTSWLTNDNPESNVPVVWDDADGKLSPLCIAMNSLIVVHALRPDRLMASAHRVVSTAFDDHFMQQDKVVDILSIVDNEVSPSEPVLLCSATGYDASGKIEDLAVET--NRQLTSIAIGSAEGFNQADSALG---TATKSGRWVLLKNVHLAPSWLAQLEKRLHSMKPHAQFRLFLTAEIHPKLPSSILRASRVVVFEPATGLKANLLRSLSSIPPQRLTKAPT-ERSRLYLLVCWLHALVQERLRYTPLGWSTAYEFSDADLRVACDTLDAAVDAVAQGRPNVEPERLPWTTLRTLLSQCIYGGKIDNQFDQVLLDCVLENLFTAKSFEQDHVLIPKYDGDDSLFTPNMSKKDQMIGWVEELKNEQLPAWLGLPNNAEKVLLTKRGESMLRNMLKVTDEELAFNEDGKEEVKPQWMAQLGELAKQWLQLLPKEIVKMRRTV------ENIKDPLFRFFEREVNLGSQLLKDIRRDLNEISAVCRAEKKQNNETRALAASLQKGEVPTGW-KRYTVPREVTVMDWMTDLNERLKQLIR---IGGADNLKRETFWLGGTFSPEAYITATRQQVAQANTWSLEQLNLHIHIGRTDSTDVF--RISGIDIRGA 4495 HSP 2 Score: 694.115 bits (1790), Expect = 0.000e+0 Identity = 404/1072 (37.69%), Postives = 625/1072 (58.30%), Query Frame = 3
Query: 3372 DCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIR----LQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVE--NWLGNLNNEMKTTLSDQLSYALQDL-RMSNQS----NYGINADKYPSQILCLSEMIHFTARCEELLNEN-NIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKD----QGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIK-NKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMV--SLKGQH-----KKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKF-YVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQV---VKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWL 6488
D H E ++ T+ E ++ + +W + TG+ ++ WLS + R + L + +L+ + T + +++ + Y + ++ ++ E L + HW +M + M L LTL + DA +I+RH IK++ AQGE+ + E +RE+ + +LV Y N LIK W D+ +++ ++Q L ++K SPYY+ F++ A W+ KL ++ +QR+WVYLE +F +A LP E SRF + D ++M V + R+L + +M G + LL + D L + QKAL EYLE +RS FPRFYF+GD+DLLEI+G S + I+ HLKK+F GI +D N++ + I S +GE V+L +++ T +V +WL L EMK TL+ QL+ +L +M+ Q+ +Y DK+P+Q++ L+ I + E+ L + +++ +VK L + ++ + + K+++LI + VH D +L+ ++ ++ WL+ +RFY K + CV++M +++F Y +EY G +LV TPLTD+CYLT+TQ +H LGG+P+GPAGTGKTESVKALG GR VLVFNCDE D ++MGRI +GL + G+WGCFDEFNRLEE +LSAVS QIQ IQ+ ++ + L+ +R+NV+ N IFIT+NP GY GR LPDNLKQLFR +AM++PD LIA+V+L S GF+ A+ L K+V +F L +E L+ Q HYD+GLRALK VL A N+ + K+ G+ +E+V E ++++Q++ + KL D SL+ DVFP I + L + V E ++ ++G+ K+L++Y+ G+++VG SGSGK+ WK+L AL + +V++ KA+ + L G +D +TREW+DG+ T R++ V+ + + WII DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV IFE DL A+ AT+SR GM++ S E + L +L
Sbjct: 1275 DSAHAPSEGDKLTVATE---ELAAMKDVWKALQPVYTGIDEAKEKTWLSVQPRK--IRQSLDELMNQLKQLPVKCRTYKSYEHVKQMLHTYGKMNMLVAELKSEALKERHWHQMMK--EMRVNWNLSDLTLGQVWDA--DILRHEHTIKKILLVAQGEMALEEFLREMREYWQNYEVELVNY----QNKTRLIKGWDDLFNKLKEHQNSLSAMKLSPYYKQFEESAQSWDEKLNKINAMFDVWIDVQRRWVYLEGLFSGSAEISTLLPFESSRFATITTDVLALMKKVAASPRILDVVNMQGAQRLLERLADMLAKIQKALGEYLERERSSFPRFYFVGDEDLLEIMGNSKDITRIQKHLKKMFAGITAIDINEEDRSITAFHSREGEKVDLV-KIVSTKDVRINDWLQALEAEMKHTLARQLAASLTHFSKMNIQTMTTDDYVEWLDKFPAQVITLTAEIWWCDEMEKTLADGKGAENVEQAVVKTLELLADSVLKEQPP----IRRKKMEALITELVHKRDTCRKLVSMKIRAANDFGWLQCMRFYFDPKQVDPVRCCVVKMANSQFFYGFEYLGIQERLVRTPLTDRCYLTMTQALHSRLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRILVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQTIQEAVRAGGDMSVDLVGKRLNVNSNIGIFITMNP---GYSGRSNLPDNLKQLFRSLAMTQPDRQLIAQVMLFSQGFRTAETLANKIVPLFILCKEQLSDQCHYDFGLRALKYVLVSAGNI---KRDKLDKMGSAALEDVA----EQQMLIQSVCETLVPKLVNEDIALLFSLLSDVFPGIHYTANQMRELRQQLSTVCDEHLLIYSDVQGEMGSMWLDKVLQLYQITNLNHGLMLVGSSGSGKTMAWKVLLKALERWENVEGVAHVIDAKAMSKDSLYGVMDPNTREWTDGLFTSVIRKIIDNVRGEADRRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSIPPNVRIIFEVADLKYATLATVSRCGMVWFSEEVVTSEMLFERYL 2318 HSP 3 Score: 72.4034 bits (176), Expect = 1.201e-11 Identity = 99/439 (22.55%), Postives = 172/439 (39.18%), Query Frame = 3
Query: 789 YPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLI---------------KRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPH---------RERQEFKIEE-------------AFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIH-RSRQG-KVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVL-----KDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRR---LDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQ 1964
YP R L+E I+ +L + L+ A E ++Q + S W D DK I K WK HK + RL +I R HEQ ++ RER++ I+ A+++ N+ L + P W+ A K++ I ET I TRLK + S+ ++ +F RYN L RP+I + + + L+ ++ +L+ F R QG K+ T +KI+W + E +L + +VL +DG + + NF +++ Q F++W + + + L + R+ + GR M+L L +NY L +EV L +G+ + ++ A + A L + A+ + ++N + Q
Sbjct: 368 YPLQRALRLVEAISRDLNSQLLKVLSSYNLMRTPIAEFNEIMSQCQALFSKWDDEYDKFIALLRDINKKKRDDPSKLSWKVTAVHK-------------RLETRLMQILQFRKQHEQFRTVIERVLRPVGNGSREREQLMIDSSEGEKSPDEQVDIAYEFLKNVDFLDVD---SPAWENAFKRYEDQIGVVETAITTRLK---SQLESSRNSNEMFSIFSRYNALFIRPRIRGAIYEYQTRLINRVKEDINELQARFTKARGEQGVKIMQTVGLPPFSAKIMWIRNYERQLQRYMKRVEDVLGKQWENHVDG-RQLKADGDNFKVKLNT--QPMFDEWVESVQSQNWTLPNKILTVDRVQVDGR-MQLQ-----LKINYHSDSSVLYKEVSHLKSMGFRVPLKIVNWAHQANQMRPSATSLIEAARTFASVNAALASVQ 778
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Celegans
Match: dhc-1 (Dynein heavy chain, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q19020]) HSP 1 Score: 715.301 bits (1845), Expect = 0.000e+0 Identity = 521/2030 (25.67%), Postives = 1010/2030 (49.75%), Query Frame = 3
Query: 6894 LILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKE-SERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY-DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEW--SVEVQDSLN-DVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIP-----YMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCP------------VEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMG-TMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEK---TGLE-KFDMRK--FLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEIS--TDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHC-CRPDLFKP---QEWELFTGT--FISDKSDRNITVPKWID-----ADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIP---QSLKNKLS----LFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSS-MNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQG----QADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILD---QIIKKSNRNIQ-----WKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFN------DSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQ-LRILQR---FSVHGTKFDKDIWSRELNPVLNRW-KILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEE--PFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGC 12746
++ T D R+ WL +P +L GP G GK++ L + + ++V ++ S+ TTP +L+ + C + G V P + S+ L+++ +INLP DK+GT ++ISFL+Q++ GFY S+ +V L+ +Q V + N + GR +++RF V + + YP + L IY + + +LK + Q L N M++VY + FT DD HY+++P +LT+WV + P+ S +A L+ + ++E++R+FQDRLV+ + R+ D ++ T + + + ++L + + W SR +T E L+D + L + E D+ ++LF ++ D+V ++DR+ + G +LL G +G G+ T S V+ ++ + + K+H Y F D+++ L+ AG E + ++++ L+ +LE +N+LLA+GEVPGL+ +E ++ +K+ A G L +F ++ LH++ M+ S ++PA F C + W WS +++ ++ M +++ E +LT + +Q T D + + +H T V T RH+++FIK ++ ++ +K++++E + H+ +G+ KISE +E V EL+ +S L EK+ A+ LK++ Q A E K E+L + E+ +A++K ++++LA +EP V +A+ AV IK S L E++++ +PP ++ LE + +++G + T W ++R + K I FD +T E Q+E+ + FD N RAS+A P+ W +A + YS L K+ PL NE +L++ ++ K ++ ++++++++ Y++++ + A ++ +L + E ++ + +L+ L +E +RW+ + ++ +L +LL++A + Y + R E W GL + D+ + +L+T ++L+W+ L D+L ENA+++ + P +IDPS A ++ F + ++ + D +F LE ++RFG +L++Q+V+ +P+L P+L ++ G R ++ +GD+ ID +P F++F+ TR+ + PD + V+ VNFT T + L Q L ++ +P +++++ +LL+ + + + L +E++LL L + G IL++ ++ +L K K + ++Q E+ K+ +D + L+ S ++ + L++I+ +Y +SL + +F L T E+S TD R + L + V+ V R + +D+++ AL + R + P Q ++L G F++ + + T+P +D +++A + +++ L + + + E +P KLS ++++ ALRPDRL ++ + + + +++ I ++E +EP+L+ + G D S +++L+ + + + +A+G QAD L +++G W+ LKN+HL SWL LEK L+S+KPH FRL++TAE H + +L++S + +E G+K NLLRS + ++K + R+ + W HA++QER + P GW+ YEFS ADLR + LD + + N++ W + L I+GG++DN FD +L ++ F D V+ + + P+ + K + + +L + P++ LP+N ++ ++ L++ F+ G + K W +L + +W ++L + + ++ ++ + P+ F + E +L+K + L +S V + + E + L+ L G+ P W +++ P E D+M L + K + + + D L LG F P+ ++ A RQ A+ S+++L G ++ + + +I + I G
Sbjct: 1578 VVPTIDTVRHEMLLAAWLAE--HKPLVLCGPPGSGKTMTLLAALRSQQEMEVVNVNFSSSTTPELLLRTFDHYCEYRRTPNGVVLAPVQLSQWLVIFCDEINLPAPDKYGTQRVISFLRQLVELNGFYRTSDHSWVSLERIQFVGACNPPTDPGRHPMTSRFLRHVPIVYVDYPGQTSLQQIYGTFNRAMLKMTPAVRGLADQ------LTNAMVDVYLASQEHFTQDDQPHYVYSPRELTRWVRGISEAITPLES-LSAEQLVRLWAHEAIRLFQDRLVTEEEREWTDKLVDTTAERYFGNACRLDEALKRPLLYSCWLSRNYV--------------PVTREELQDYVSARLKGFYEEELDVKLVLFDQMLDHVLRIDRIYRQSQGHLLLIGTAGAGKTTLSRFVAWLNGLSVFQLKVHSKYTAADFDEDMRTVLRRAGCRNEKLCFIMDESNMLDTGFLERLNTLLANGEVPGLFEGDEHTTLMTQIKEGAQRQGLILDSHDELYKWFTQQVMRNLHVVFTMNPSGSGLRERASTSPALFNRCVLNWFGDWSENALYQVGSELTRTMDLDRTDYEGSVRLTPSCELVPSQPTYRDAVVNTLCLVHKTVQKFNEMETKKGHRVMACTPRHFLDFIKQFMSLFHEKRSDLEEEKIHLNIGLNKISETEEQVKELQKSLKLKSNELQEKKEAANLKLKEMLGDQQKAEEEKKFSEQLQKELAEQLKQMAEKKTFVENDLAQVEPAVAEAQTAVQGIKKSQLVEVKSMSSPPVTVKLTLEAICILLGENVGTDWKAIRQVMMKDDFMTRILQFDTELLTPEILKQMEKYIQNPDWEFDKVN--RASVACGPMVKWARAQLLYSTMLHKVEPLRNELKRLEQEAAKKTQEGKVVDVRITELEESIGKYKEEYAQLIGQAENIKQDLLSVQEKVNRSTELLSSLRSERDRWSSGSAGFSQQMDSLVGDALLSSAFLAYAGYYDQMLRDEIFHKWFNHVVNAGLHFRHDLARIEYLSTVDDRLQWQLNSLPVDDLCTENAIMLHRFNRYPLIIDPSGQAVEYIMKQFAGKNIQKTSFLDESFRKNLESALRFGNSLLVQDVEAYDPILNPVLNREVKRAGGRVLITIGDQDIDLSPSFQIFMITRDSTVEFSPDICSRVTFVNFTVTSSSLASQCLNQVLRSERPDVDKKRNDLLKLQGEFAVRLRHLEKALLAALNESKGKILDDNSVIETLEKLKNEAAEVAQKSAETDKVMAEVDAVSAQYQRLSTACSHIYHTLQQLNEIHFLYHYSLDFLVEIFTHVLKTPELSSTTDYAKRLRIITTSLFQTVFRRVSRGMLHTDKVLLALLLMRIHIRSNPSAPAYEQHFDLLLGRSDFVAKNDEADSTIPGGLDFLTVENKKSIAKARKVVGFENVFAHLQ-HNSAAVTSWLTNDNPESNVPVVWDDADGKLSPLCIAMNSLIVVHALRPDRLMASAHRVVSTAFDDHFMQQDKVVDILSIVDNEVSPSEPVLLCSATGYDASGKIEDLAVET--NRQLTSIAIGSAEGFNQADSALG---TATKSGRWVLLKNVHLAPSWLAQLEKRLHSMKPHAQFRLFLTAEIHPKLPSSILRASRVVVFEPATGLKANLLRSLSSIPPQRLTKAPT-ERSRLYLLVCWLHALVQERLRYTPLGWSTAYEFSDADLRVACDTLDAAVDAVAQGRPNVEPERLPWTTLRTLLSQCIYGGKIDNQFDQVLLDCVLENLFTAKSFEQDHVLIPKYDGDDSLFTPNMSKKDQMIGWVEELKNEQLPAWLGLPNNAEKVLLTKRGESMLRNMLKVTDEELAFNEDGKEEVKPQWMAQLGELAKQWLQLLPKEIVKMRRTV------ENIKDPLFRFFEREVNLGSQLLKDIRRDLNEISAVCRAEKKQNNETRALAASLQKGEVPTGW-KRYTVPREVTVMDWMTDLNERLKQLIR---IGGADNLKRETFWLGGTFSPEAYITATRQQVAQANTWSLEQLNLHIHIGRTDSTDVF--RISGIDIRGA 3563 HSP 2 Score: 692.575 bits (1786), Expect = 0.000e+0 Identity = 404/1072 (37.69%), Postives = 625/1072 (58.30%), Query Frame = 3
Query: 3372 DCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIR----LQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVE--NWLGNLNNEMKTTLSDQLSYALQDL-RMSNQS----NYGINADKYPSQILCLSEMIHFTARCEELLNEN-NIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKD----QGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIK-NKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMV--SLKGQH-----KKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKF-YVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQV---VKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWL 6488
D H E ++ T+ E ++ + +W + TG+ ++ WLS + R + L + +L+ + T + +++ + Y + ++ ++ E L + HW +M + M L LTL + DA +I+RH IK++ AQGE+ + E +RE+ + +LV Y N LIK W D+ +++ ++Q L ++K SPYY+ F++ A W+ KL ++ +QR+WVYLE +F +A LP E SRF + D ++M V + R+L + +M G + LL + D L + QKAL EYLE +RS FPRFYF+GD+DLLEI+G S + I+ HLKK+F GI +D N++ + I S +GE V+L +++ T +V +WL L EMK TL+ QL+ +L +M+ Q+ +Y DK+P+Q++ L+ I + E+ L + +++ +VK L + ++ + + K+++LI + VH D +L+ ++ ++ WL+ +RFY K + CV++M +++F Y +EY G +LV TPLTD+CYLT+TQ +H LGG+P+GPAGTGKTESVKALG GR VLVFNCDE D ++MGRI +GL + G+WGCFDEFNRLEE +LSAVS QIQ IQ+ ++ + L+ +R+NV+ N IFIT+NP GY GR LPDNLKQLFR +AM++PD LIA+V+L S GF+ A+ L K+V +F L +E L+ Q HYD+GLRALK VL A N+ + K+ G+ +E+V E ++++Q++ + KL D SL+ DVFP I + L + V E ++ ++G+ K+L++Y+ G+++VG SGSGK+ WK+L AL + +V++ KA+ + L G +D +TREW+DG+ T R++ V+ + + WII DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV IFE DL A+ AT+SR GM++ S E + L +L
Sbjct: 343 DSAHAPSEGDKLTVATE---ELAAMKDVWKALQPVYTGIDEAKEKTWLSVQPRK--IRQSLDELMNQLKQLPVKCRTYKSYEHVKQMLHTYGKMNMLVAELKSEALKERHWHQMMK--EMRVNWNLSDLTLGQVWDA--DILRHEHTIKKILLVAQGEMALEEFLREMREYWQNYEVELVNY----QNKTRLIKGWDDLFNKLKEHQNSLSAMKLSPYYKQFEESAQSWDEKLNKINAMFDVWIDVQRRWVYLEGLFSGSAEISTLLPFESSRFATITTDVLALMKKVAASPRILDVVNMQGAQRLLERLADMLAKIQKALGEYLERERSSFPRFYFVGDEDLLEIMGNSKDITRIQKHLKKMFAGITAIDINEEDRSITAFHSREGEKVDLV-KIVSTKDVRINDWLQALEAEMKHTLARQLAASLTHFSKMNIQTMTTDDYVEWLDKFPAQVITLTAEIWWCDEMEKTLADGKGAENVEQAVVKTLELLADSVLKEQPP----IRRKKMEALITELVHKRDTCRKLVSMKIRAANDFGWLQCMRFYFDPKQVDPVRCCVVKMANSQFFYGFEYLGIQERLVRTPLTDRCYLTMTQALHSRLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRILVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQTIQEAVRAGGDMSVDLVGKRLNVNSNIGIFITMNP---GYSGRSNLPDNLKQLFRSLAMTQPDRQLIAQVMLFSQGFRTAETLANKIVPLFILCKEQLSDQCHYDFGLRALKYVLVSAGNI---KRDKLDKMGSAALEDVA----EQQMLIQSVCETLVPKLVNEDIALLFSLLSDVFPGIHYTANQMRELRQQLSTVCDEHLLIYSDVQGEMGSMWLDKVLQLYQITNLNHGLMLVGSSGSGKTMAWKVLLKALERWENVEGVAHVIDAKAMSKDSLYGVMDPNTREWTDGLFTSVIRKIIDNVRGEADRRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSIPPNVRIIFEVADLKYATLATVSRCGMVWFSEEVVTSEMLFERYL 1386
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Celegans
Match: dhc-3 (Dynein Heavy Chain [Source:UniProtKB/TrEMBL;Acc:G5EDV4]) HSP 1 Score: 87.8113 bits (216), Expect = 2.322e-16 Identity = 116/576 (20.14%), Postives = 239/576 (41.49%), Query Frame = 3
Query: 3573 LRNAEITTMTIRLQKEIDM--YKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKN----ALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNL-LSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDG-EVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKY----PSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSM--GRIFIG 5258
++ E T+ L+ EI + ++ ++P+L I + + HW + L + + +E L L I A+ +++ +A+ E + +I +++ A F + Q + + + + + +Q +L SP+ D W + L +L+ ++ Q +W +E +F +P E F+++ + I + + +L + NL LS + R + + YL +KR++FPR + + D+ +L ++ S P KS++ LF + D N ++ I L+ +V+ N L VE W+ L++++K TL ++ ++ + NY ++ + P Q+ + I FT + E + +N++ L EL + +A + F+ L + + H ++++L+++ + ++ W QLR+Y + I++ Y YE QG ++ L D+ H G G G + ALG F + + ++ ID K + G + G
Sbjct: 667 IKEHETTSKEALLKIEIVLAEFEKLLPVLGAISCQAMKDRHWKMI--LQDSETSVKVEGNPLVSEL-LEMNFIEKADKFEQVGAQAEKERVLETSIEKMKSQWVTATF-----VTHQGGELLTTELNVQMQAHLARSQTIL----SSPHAFSILDHIRHWLDTLLNLNTFVHLYKQCDTRWRKIEGVFSTEDIAYQMPHEFRTFKKISLRWLHINNQITEERPILEQMDLVQQLNLELSELEVLFGRMENGFHAYLRKKRAVFPRLFALSDELVLSLICDSREPANCKSYIPLLFPSLTTFDQNTKMEIISVSTKLETISLVKPVNVNLSKRHVEKWMHELDSQIKYTLRTRIRLLIEKM------NYKLSPVETILNEPIQVAAVYLKIAFTWQMENSMKQNSLTILASELKICIRDCQHAVLHKHDRWEFLP---VLYHIYKSSTH---LVNKLMNEQVIFIDDYRWTSQLRYYWHL--ENVFIRVGTVSTRYDYEVQG-VDCMIDNQLVDEAVKYFICMNHFGFNGFVNGMDVNLARQIAGALGKPFA----ICDTEQEIDCKMLIEGALLFG 1211 HSP 2 Score: 86.6557 bits (213), Expect = 5.412e-16 Identity = 87/363 (23.97%), Postives = 165/363 (45.45%), Query Frame = 3
Query: 8751 KKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKI---TSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGT------------MDTSWVSMRNFLGKRGIQEEIQTFDARRITRES-RIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAP----LENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQ 9779
KK+ E+ + G++K+ A+E VA ++ + L +E + I T ++ A E E K E KA + ELA P ++ A +A+ + SD+S ++ +R PP +R +E V +++G ++ WVS + L +I++F +++++ ++ E+ L+ K+ FDP+N K+ S+AA L WV A Y+ + + P L + +K++L+ E K K L K V + + G F + +LE ++ + + AE LV L E ++W +I + E S S+ ++ ++ P DQR+++++
Sbjct: 2113 KKREEVRKTMTKYEKGMEKMKRAEEQVAGMQGELLRLQPQLVRTSIETSMLMSTIEKETIDVENAREVVAANEN---KANEAATKAQSLKAESEAELASAIPALESAVEALETMTQSDVSSLKTMRFPPYAVRLCMEAVCILLGVKPAKITNEIGEVVNDYWVSGQKLLSDIHFLAKIRSFARDTVSKKTVKLIREKYLS--KEEFDPENVKQCSLAAEGLCRWVLAIDMYNQISKIVEPKRERLRKAEVLVKQHLKQLEVKRKALLK----VTEKLQGLSDQFSQMCQKKQELESQISSCEVRMERAERLVQALSGEKDKWKNKITYITHEDSLSVPYSVGSSLALHVFGKLPIDQREKELR 2466
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Fly
Match: btv (gene:FBgn0023096 transcript:FBtr0273418) HSP 1 Score: 1987.62 bits (5148), Expect = 0.000e+0 Identity = 1370/4324 (31.68%), Postives = 2326/4324 (53.79%), Query Frame = 3
Query: 366 VTTLSENPISSLYNIIQNIYGP----ILLSDTDPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSL---SASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFS-YLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMT--------RRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPN-EIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQME--PEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQ-STNPQVIKSHLKKLFQGIYDVDFNK---------DIQH--IITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKD----------QGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFT--ISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQ--PFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQN---SKVKL--LANTMIEVYSQLKSKFT--VDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSH-MHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQF-LEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGL-EKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQ-------GILIPFLIDPSSNATAWLKNHFK--DRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIA-CLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNIT------VPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWF--HAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRN-IQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYG-KIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWS-----------------RELNPVLNRWKILNQGLNIIKASLPDSLKRSSTD---SPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGS-ELLTKEVQNLSECLLTGQTPNVWLQQWEGP--EEPFDYMRILILKAKAVEKWAELSEKDEL-LSTILDLG--ELFHPDTFLNALRQLTARTIKISMDELKF-VCRWGGSNVSAKYS---VKIGNLHIEGCLFDGTMITECN--------RDSNSIVLLPPVSVGWVDKNQPNSYSEDDMIS---LPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLK 12989
+ TL + S+YN + ++ P S+ P++ ++ L LGS + P S GI S+ +EI +W L S+S D+ +++ I L+ + +++ I + + + +L++ L+++W+ + NYPQ RM L++II L+ + TQL W + + V ++Q+I+ WI +CD L + +W Y+ H W D+++ F+ RL+EI S++ +++QI +L E QE E+A NI + + W A++ F + ++P + I LK S P+Q++ +F +Y LI RP + L ERE L L I + LR+ + + + P T + S ++ W K ++ ++ EI + S+++ +GF+K K + EE + + FE W+ + + R DD + ++ + +GR L+ V ++ +LV ++VR LGY++ + AAA + K+ A L+Q+A F+NTI +MIPCQ+ +ML A+ ++LV+S V W + + +++D LQ A + S N LL H ++ LM DL Q Q WKD L +R+++ +E Q + + +K H DHQLYK LEYQY +GL +N LP+I V LV RQ L F+P EEI+ YF ++++FI P F GL++ S Q +F S++ N F YQ+A LF +L + WI LG +D+++ H + D+++NF++ K ++ KL E IDCI +N P++ ++ + + +++L NSLR I + + +L ++++ L P I+++ + + + +I ++ ++ L + +S + +W++ + ++E+ +++Q Q++++K ++ + + + KF RW+ + + + LD ++ + +L+E T L ++C F ME E T EI + +++ W ++ + T LQ + E+W +R R Y+ EF+ +W E +A I + R++++++ + +PIL+ ++ E LS+ HW +F+LLN L ++ L+ IL + A+ I + ++A E +R+A+ EL+ W A +L+ D+ S+SLIK+++++++++GDNQ LLQS +S + F D+A +WE++L LD L +LN QR+WVYLEP+FG L E++ F+R+D+DFR +M ++ + RV SL ++ + +++ + QL RCQ+ L Y+ +KR+ FPRFYF+GDDDLLE+LGQ S + +VI+ H++KLF G + + + D+ I ++ S +G+ ++L V + ++E WL L ++ TL DQ+ + + KY SQ+L + +HFT + E+ + ++ LK++L ++ + A + S + T I LKL++L+LD VH + +QL N ++W WL QLR+Y K Q CV +MV AEF Y YE+ G A KLVHT LT +CYL LTQ MHMGLGGNP+GPAGTGKTE VKALG++ GR VLVFNCDE +D +SM I GL +CG+WGCFDEFNRL+EA LS++SM IQ IQ +K + + + ER++ ++ + IF+TLNPAG YGGRQKLP N++ LFRP+ M +P+ IA V+L +GF A + ++V +F LS ++L+ Q+HYDWGLR LKTVL L + ++ ++ N N ++FE ++V+ LR +T+SKL D FE L+++VFP I L ++ + + + Q +K L+++EQL++RMGVV+VGP G GKSTI LL+ AL G +K + ++PK++ R QLLG +D DTR+W DGVLT++A V +E ++ SWI+CDG IDPEWIE+LNSVLDDN+LLT+PSG RIQFG NVNFIFET D+ ASPATISRMG++ +S + ++ L K+ D LL +Y+D F +++WI + T + + + L L ++ + ++ L G + + + FA + + + N + +Y +N L E+ ++D + + +K + LI+T+ ++ LD + L + + PF+L GP G GK+L+L + Q+ T++CS Q TP ++L L C+ ++ GR YRPK++ RL+L++K+++L + D WG +++ L Q+ GFY NLE++G+ G+Q+ S ++ R+ +I + +S P+ + +I L+P+L+ +H S+N S V L ++ ++++ + +L++ FT +HY F+P + + + +L+ Y P + N A+ E + +F+DRL+S + ++ +GIL T+ + E V+FV + L LT + + + R + + E + + +E+ +VA++ RVL++ +L+ G+SG GR ++ + K+++ + Y+L F NDLK +QTA +E + LL+E P L+ I +LL E+ L+ ++LE + +LK A G++ S+ YF R + YLHII+++D ++ + PA + + ++ SR+++ +P I +L S G S+F D+ D P E TS+ Y I+ Y +Y NEI+ R +Q+G+ K++ A +V LKS AA Q + L EK+ A++AL+ I+ M+ A E+K M +L +T + + L R+ I ELA +EP + +A +AV IKS LSEIR+LRAPP+ +RDILEGVL +MG DTSW SM+ FL KRG++E+I++ D RI+ E+ VE LL DS++ KNAKRAS AAAPLAAWV+A+V+YS ++ I PLE EQN+L++NL AE +M++L G+ DVDK V + +T +AA LE +L+ A+ T+ AAE LV KL E+ W+ Q+ EL L K+LL A ++ Y +QR ++ L FD+R L TE++Q+ W+ +GL+ D +E+A ++ + IP L+DP+ A AWL H K R E+ + LEL+VRFGKTL++ + + L P + LL+G + + ++ + +G KL+D + F+L L +++ + LP + + ++ + FT T AGL QL++ + +LE+++ LLQ+E L + +M++ LL++L+ + G+IL N+ LL SLN+ K+ S I ++L++S +++ +L + + L+ ++ + + + Y S ++ LF AL+ S+ R+ S + CL + VY + R+ + +L +L + H PD P+EWELF F+ SD ++ +P + + + ++ L P+L S L ++ D +W F E + L S FQ++LI Q RPD + L + D+L + + + ++ Q+ + ++ + PIL++ DP+ +L++ + +++Y ++A+G+G L+ + + + +G WLC+KN+HLV +L +E+EL+ ++ KDFRLW+ E GFS + LK+ YE P G+K ++R N++ + K + ++ + L +F A++Q+RR FIPQGW+K+YEF ADL+A IL + ++ N W + L E +GGRV+N D+ +L++Y+ ++ + V++ + G + +P++ +DY A + +L D + PS + L + + + + +VI +LR L +G KD +++ P+LN W+ L II+ ++K + TD SP F+ E L VH +L + LK S E+ ++ L+E Q P WL+ W GP D++R LI++A+A AEL ++++ L + D+ ++F+ + L+ L+ L +R + +S + L+ C G SN+ + S +K+ L I+G + + + N +D V S KN + YS + S LP+Y RDK++ +++ +G ++ + +G AL ++
Sbjct: 91 ILTLEGGMVKSIYNSVSRVFSPSANSARRSEYGPELSGILENLHQNLGSSLGLPQS-------------GITSLRNEIKYWQQKLGQKSSSRLDREAAQV--FIGVLENMEKQISTIDGANPSGTIEEFLDHAHTNLDELWR---LPYNYPQQRMADLLDIIGKRLLEVCLTQLLAEDVWSLNSSHVNNLMSQSIDTVDAWIQLCDSLTRLFWPNYVKHPWLGDSHVP-KRGQQFKERLSEIRSIKQLYKQIATLLEDTELQEMFQEQAPFTEFNIFDTS--SLGQNKWHKALQHFEQVLQPIDERIAAALKRQLHNHLSN--PRQVIFIFSKYETLIQRPAVLELLTIEREQFLQSLHILLQDLRKAMVDSNME---PDTGHLSVICNECRWLKVVQHQIQEIEKV-SHLISGREGFDKINKAVQEIKEETESLLRTNFEIWSGQCSTAVKSGELRLRDDQAV--VKFEKEGR--------QLMRVTFNPKLVTFCQDVREFENLGYNVPLELRAAATHAAKYMCYARRLQQIATFHNTIGDRMIPCQRPIMLKNALELQRLVQS--------ETVAWQDESSVQRYVDILQAAVSKLSSDNTLLVGYHEQAKRSVLKLMSTDLFTQNQIWKDELRHLRELVATLERQGYTHLDA--FKLHWDHQLYKVLEYQYILGLLDMNNKLPDIHVKLVLRQRELVFSPPEEEIRELYFSQLRRFIERPCNFHGLSEHS---QELFKSMVTVNRHHFGPLYQRAAELFDKLQDFKTIWLPWIALGCVDVDQLCGIHLNEAGDWDRNFRSCKHFSQQLAKLQQAEESIDCIVINVLPLRSDIEYISRRYWESLANSLRTAILTDVSLIQEFLQSALQFLQNVPMDEGSISQSGMKYEKIMSKLPQIEKTLEAVRAKDSCLGGWCKERVTALSGILLQWEQLQPLLENHAVILQRQVDMIKNQAETQLQNLKNEAEKFLLRWESTISELE----ANEHSTLDVFKERRLHWQQLQEKK---TQLLEECSKFNMEFPAEMLTPFTEIEEQMEKQSKQWQVYDSFLTELQPVLHEEWAIYRRRPYVLNEFIGKW-EGSVHASIDLPSKRIRQQVEQLQSALPILQQLQSESLSERHWARIFQLLNHKETKPLHSILLQDILQDFDVLQSAAQEISSIVRQASSEQIVRQALIELDQWSVTAQLKLITRTDASGQSVSLIKDYQEVLNKIGDNQSLLQSANNSAAFESFSDQAELWESRLNTLDALLSSLNHSQRRWVYLEPVFGSGTLQHEQALFKRIDKDFRFVMREIEMDPRVTSLTKINNITTIVNALETQLARCQQNLMSYITDKRNSFPRFYFLGDDDLLELLGQASKDAEVIQRHIRKLFPGCHSLSIRQVGPNPATSSDVNQYSITSVHSAEGDELKLSQPVEMKGDIERWLNQLVTVVQDTLRDQIYECYTGTTGGSDNLDEKILKKYASQVLATARALHFTRQAEQAIGSMSLGKLKQQLKDEIT-HLAALKNKSENGTLI--SLKLRALLLDLVHYSGVTEQLQKHNVVHTSDWHWLCQLRYYLGKKGGTSGEVNANRQVCV-RMVYAEFEYAYEFLGQASKLVHTRLTHRCYLILTQAMHMGLGGNPFGPAGTGKTECVKALGAMLGRLVLVFNCDENVDTESMSLILTGLARCGAWGCFDEFNRLQEATLSSISMLIQPIQSALKERANSVQIGERQIQLNQHCGIFVTLNPAGAEYGGRQKLPGNIQALFRPIVMQQPEPGEIARVMLFVEGFTEASAIASRIVELFELSGKMLSAQRHYDWGLRELKTVLMVCGEGL---RDQLTSEDN----NQSSANFEMSVVVRCLRSSTMSKLAPHDVNRFEMLLRNVFPEIGSSPAPETQLHQSLSAAFAQLGLCRSERQIEKALQLHEQLQKRMGVVLVGPPGCGKSTIISLLKQAL--CGTQLKVHTISPKSMSRIQLLGRLDADTRQWQDGVLTHTAVAVNQESSQVHSWIVCDGSIDPEWIEALNSVLDDNKLLTLPSGWRIQFGSNVNFIFETDDVRHASPATISRMGIVNMSYDYYPADGILKHELSKEPYGD--LLQSYVDGNFQYAVNWIESQLLLTHLPGINRAHLLRSLLLQLHGTQSLEEYGAATLRALFGYMPNDRQREFAQLILKHANLYVANPNYAELTHY--ESSRNSL--------EQYAVDAIETPEKG-SQLIITSYMKSYLDILETLLKTQGTRLPPFMLIGPSGSGKTLLLQRAVLENSGYQLATINCSTQLTPRYILHTLKTHCVTVSGIKGREYRPKQA-RLVLFMKNLDLCQQDSWGACEVVELLFQLAQRGGFYAENLEWIGVSGLQLCA----SIGGNTGKIAPRYFAINQFVRVSRPTSQDMLEIVQRRLEPLLE----EHFRGSENRGRSGVNLQHVSESLMDCFEKLQATFTNVGGRQAHYQFSPKCIMKLLDALVFY--PASDFNEALYC------ELLGMFRDRLISEEHVQQFEGILKQTMRKYYGKE------KVFFVPKSPK-----------SRGHLHCLTHDEWMEEVQRQVTICNTENYSITAPITEELLSHVARITRVLSRTDAHMLILGQSG-GRHLDAIFTAATFQEAKVVTLQGGPSYDLTDFYNDLKVAMQTAALEQQMSYLLIEQCWLSYVPDILKPIEALLEGSEILELF-GDDLETVASTLKQAAQLEGYQESMGTYFLKRARDYLHIIIVLDPNSAKVQDYFNNFPALHRQMDLLYVRGESRETIAILPKQFI---------ELLNESIAGGGSGRGKVPTCSHFADISDELPSE-ETSQRYYQLIRTYFHMYNNAANEIDQRLGKLQMGVDKLASAHALVDTLKSNAAAQEQALGEKRQLANEALEMISFTMRNANEQKSSMLELKQQTQKSSEQLKIRQKEIQQELAEVEPILAEASNAVGQIKSEALSEIRSLRAPPEAVRDILEGVLRLMGIRDTSWNSMKTFLAKRGVKEDIRSLDPARISPENCEAVERLLLAKGDSYEAKNAKRASAAAAPLAAWVQASVRYSRVIQSIKPLEREQNELQKNLNAAEDEMQELASGLDDVDKRVKQLSAKLQTYTQEAAVLELKLQEASGTLQAAELLVEKLSAEYTTWSLQLTELKKAHKTLDAKTLLIAIAINYCAGLGLEQRCSSLKRLAADFHLPSDFDLRGSLLTEQQQIIWESQGLARDAQIIESAALLREMLSLPYGACPIPLLLDPTQTAAAWLMAHLKGSGRPCELTTHGNDRLPYQLELAVRFGKTLLVTDCEQLRPPVLQLLQGHVFVRFNKRQLAIGSKLVDLHESFQLVLISKSHRLDLPEEQRSQLNVLKFTVTAAGLADQLMSKAIVLKNGELEQQRIELLQKEGHLLKQRMEMQDKLLEQLSKSEGDILKNEQLLESLNEIKQGSTQIDEALKQSGQIRDTLLAQFGSLRELSSRAATFY------AGLIQGYELSPLVYIELFLGALSKSQ-------RDESKVYDCLVRSVYMNLARATSRDSQLSLSLWVCHQAYPDRLNPKEWELFVNNFMGS-SDGSMVLSQLGKLPDCMPKEAQLKLAMLLQLFPDLRSKLQLEKDYIWRGF-----IEAQADDVLPALGSSFQRVLIAQIFRPDLMLHQLRKVSSDLLGISPDASTQPSVEQLLQ-QSSCDRPILMVSHAENDPTTELRKWA-----NQKYREMAIGKGVEKRVLSEMRQAAIDGHWLCVKNVHLVPEFLTQMERELSEIQKSKDFRLWLLCESTEGFSEAAIYKCLKVRYEQPKGLKQIVMRLLQNFAAEQDQKLKNQPKSLKM-RLVYFVLTAVLQQRRQFIPQGWSKYYEFGEADLKAALGILRMMDQQLNSGKCDWLLMQRLSEALAYGGRVNNQRDLEILTTYLNQFCSADVLSNRWSPLGLSLSIPTSGQLQDYYAALEKLPDTDEPSMYGLANQAQQQREIEQAKRVIKELRGLH----YGRGLAKDSGGAGESKGNDQLTGRQKLEQQIKPLLNLWRKLAASCTIIQ-----TMKEAKTDVGESPWALFVLAELKLGADLYGIVHQTLSQMHAWLKESQEVDGSTLRTLAE----QQIPASWLKLWPGPGSNSAVDFLRALIVRAQA----AELRFREQMHLDFVEDINFVQVFNCENLLSCLKLLQSRKLAVSTERLELQTC--GSSNLESDSSDIILKLAPLKIDGA---QSGMGKSNPFYIKYKIKDEVQNVSHTTTSSSKYGKN--SLYSTQNAESKPKLPLYSRSSRDKLICHLNVDIVTGTAEQILLAGTALIVE 4234
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Fly
Match: Dhc64C (gene:FBgn0261797 transcript:FBtr0332745) HSP 1 Score: 1382.85 bits (3578), Expect = 0.000e+0 Identity = 1018/3530 (28.84%), Postives = 1777/3530 (50.34%), Query Frame = 3
Query: 3087 VSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQME--------PEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRL---------QKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITS--EVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINA-----DKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTF----IVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFY----QKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQE------ITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANL----LEMHKSKMKTQGNDTIE--NVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHK------KMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKI-GQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQ-EI--QSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATI-----------------------SRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHL-----LSTYLDDFFYKSLDWIAKRN-EFTISTSNVG--TVYNGLSNLKAIKNKAHFSV---------------------------CLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEK------QNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESER-LILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY-DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAV-SLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX-XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQN---SAKP--KTQLTGSDNLNSYFLDLHDTCPVEFS------------TSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENE----QNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMR------KFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTS---EISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFT--GTFISDKSD--RNITVPKWIDADRTVAISNLASAMP----ELWSVLNIKDDDLWHQFAKSSECEREIPQ------SLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHL--SPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQG----QADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSN--------RNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFND----------SVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRF----------------SVHGTKFD-KDIWSRELNPVLNRW-KILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPE--EPFDYMRILILKAKAVEKWAEL---SEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRD----SNSIVLLPPVSV-GWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQD-KWIQSGVALF 12983
V ++ +W F +++ +Q Q+ ++ I++ K + + F + W+ KP +G DA+Q+++ + + L + N+ K E +++ E + E +D+ + +WS+ + T + ++ WLS + R L Q E + A++ + RL +K I Y + ++ ++ + L + HW ++ + L + L L+L + D + ++ +K++ AQGE+ + E ++++ L+ Y N +I+ W D+ ++V ++ + ++K SPYY+ F+++A WE KL ++ +QR+WVYLE IF +A LP E SRF+ + +F +M V ++ +V+ + ++ ++ L + D L + QKAL EYLE +R+ FPRFYF+GD+DLLEI+G S N ++ H KK+F G+ + N++ I+ + S +GE V N V ++ WL + +M+ TL+ L+ A+QD++ A DKY +QI+ L+ I ++ E L + + K + + L + +++ ADS + KL+ LI + VH + +LL+ S ++WL ++RFY Q Q I M +A F Y +EY G +LV TPLTD+CYLT+TQ + LGG+P+GPAGTGKTESVKALG+ GR VLVFNCDE D ++MGRIF+GL + G+WGCFDEFNRLEE +LSA S QIQ IQ+ +K ++ + L+ ++V V + AIFIT+NP GY GR LPDNLK+LFR +AM+ PD LIAEV+L S GF++A++L K+V F L E L+ Q HYD+GLRALK+VL A N+ + K +MK +G++ I+ +V ++ E ++++Q++ + KL D SL+ DVFPN+ E L I +V +E +V +G + K+L++Y+ G+++VGPSGSGKST WK L AL + G +V++PKAI + L G +D +TREW+DG+ T+ R+++ + EI + WII DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV +FE DL A+ AT+ SR+ I L D ++ K++E L ++ L FF S D I R E+ + ++ T LS+L ++ N+A +V ++ G+ R +V +T P +++Y N N++ E + S D I+ P T D R+ WL +P +L GP G GK++ L + L ++V L+ S+ TTP +L+ + C + G V P + + L+L+ +INLP +D +GT ++ISFL+Q++ +KGFY S+ +V L+ +Q V + N + GR LS RF V + + YP + L IY + + +L RL+P + + L N M+E Y + +FT D HY+++P ++T+WV + P+ D+ V L+ + ++E++R+FQDRLV R+ W+ E D + F E K + E L++ + L + E D+ ++LF EV D+V ++DR+ +P G +LL G SG G+ T S V+ M+ + + K+H Y + F DL+ L+ +G + E I +L++ L+ +LE +N+LLA+GEVPGL+ +E ++ K+ A G L +F ++ LH++ M+ S ++PA F C + W WS ++ ++ ++ E+ + + S P T D + + + +H T + T RHY++FI ++++Y +K++++E +Q H+ VG+ KI+E E V E++ A + + L K A+ LK++ Q A ++K + +++ ++ ++ V + +++ + +LA +EP V A+ AVS IK L+E+R++ PP V++ LE V ++ T W ++R L K I + +IT + R +++ D ++ + RAS+A P+ W A ++Y+ L+++ PL E + Q NL +A K+ KDL V +++++A Y++++ + + A ++ +L+N + + L+ L E ERW +++S + LL+AA + Y + R W + R ++L+ E+L W+ L +D+L ENA+++ + P +IDPS AT +L N + +K+ + D +F LE ++RFG L++Q+V+ +P+L P+L +L G R ++ LGD+ ID +P F +FL+TR+P + PPD + V+ VNFT T++ L+ Q L ++ +P ++E++++LL+ + + ++ L ++E+SLLQ L +A G IL++ ++ +L K+ + I+Q ++E+ K+ ++ +LPL+ S+++F + L++++ +Y++SL FL +F L + E TD + R + L ++ YE V R + DRL FAL M C+ L E L F+ + N T + + A++ +++ LA +P L V +I + W Q S E+ +PQ +L S ++L+IQA RPDR+ +A VL + + ++ + + + N P L+ PG D S + +L+ + +++ + +A+G QA+ +N+ + G W+ LKN+HL WL LEK+++SL+PH FRL++T E + LL++ +E PPG++ NLLR++ + KT S RA F LAWFHAI+QER ++P GW K YEF+ +DLR + LD I + + W + L +I+GG++DN FD R+L+S++K+ F + V+G+ I +P + +L I L+D +PS+ LP+N ++ + ++ +L +Q+ S G D + W + L+ W ++L + L ++K ++ + P+ + + E + +L++ V L + + +G + T +++ L+ G P W +++ P ++ + + ++K ++L + EL + LG L +P+ ++ A RQ A+ S++EL + G N + L ++G +C + +++I++ PV++ W+ + S+ ++LP+Y + R +++ +D+ +GQ+ + + GVA+
Sbjct: 1214 VDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKP------TGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDL---RGVWSELSKVWTQIDETREKPWLSVQPRK------LRQQLEAMM-AQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRV--NWVLSDLSLGQVWDV--NLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINY----QNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFRDGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLG-NVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNP---GYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFVGVIKPAKDKEEEVSPSLQVQRDIALLLLPFF--SADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAPIIDYEVNMSGDWVPWSNKVPVIEVETHKVASPD-------IVVP---TLDTVRHESLLYTWLAE--HKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAML-RLMP-----ALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPL--DSLPVEGLVRLWAHEALRLFQDRLVDDSERR-------------WTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCPLVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVSSIKKKHLAEVRSMANPPAVVKLALESVCELLNESATDWKAIRGILVKDSFISSIVNLETDKITDDVREKMKSKYLSNPD-YNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASA-KETKDL---VEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLM---CKIHLKGTSESNLDAEFNFFLRSREGLLANPTPVEGLSAEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQ---QSSPEQVVPQLWDESKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAE--QNKQISSIAIGSAEGFNQAERAINM---ACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPS-ERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQLEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTV------ENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGW-KRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGA--------QCKNNELLLASTIMMDLPVTILKWIKISSEPRISK---LTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAVL 4645 HSP 2 Score: 76.2554 bits (186), Expect = 8.355e-13 Identity = 87/428 (20.33%), Postives = 176/428 (41.12%), Query Frame = 3
Query: 780 NPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKL-------IKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQIL-----PHRE-----------RQEFKIEEAFKYFLNILPLAYNPYTE-----------PIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETK------NFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGL-LYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFY 1931
N YP R L+E I+ +L + + L + + + Q E+ S W D DKL +K+ ++L W Q R+ + R HEQ+ ++ P + +Q + ++ A + + LAY E W+ AVK++ I+ ET I L+ + +A+ ++ R+F R+N L RP I + + + L+ ++ + L E F +S+ ++ ++ I+W++Q++ +L L +VL G+E ++ K +F ++S + F +W +++ R + + G ++ + + + L L VN+ ++ L +EVR + LG+ + +++ A + Y A+ L + + Y
Sbjct: 369 NTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVS-----PAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPTKPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLR---DQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGK--GWETHIEGQKLKADGDSFRAKLSI--SDVFHEWARKVQER--NFGSTGRIFTIESTRSRIGRGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTY 782
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Fly
Match: Dhc64C (gene:FBgn0261797 transcript:FBtr0273370) HSP 1 Score: 1382.85 bits (3578), Expect = 0.000e+0 Identity = 1018/3530 (28.84%), Postives = 1777/3530 (50.34%), Query Frame = 3
Query: 3087 VSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQME--------PEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRL---------QKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITS--EVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINA-----DKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTF----IVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFY----QKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQE------ITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANL----LEMHKSKMKTQGNDTIE--NVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHK------KMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKI-GQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQ-EI--QSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATI-----------------------SRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHL-----LSTYLDDFFYKSLDWIAKRN-EFTISTSNVG--TVYNGLSNLKAIKNKAHFSV---------------------------CLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEK------QNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESER-LILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY-DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAV-SLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX-XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQN---SAKP--KTQLTGSDNLNSYFLDLHDTCPVEFS------------TSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENE----QNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMR------KFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTS---EISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFT--GTFISDKSD--RNITVPKWIDADRTVAISNLASAMP----ELWSVLNIKDDDLWHQFAKSSECEREIPQ------SLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHL--SPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQG----QADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSN--------RNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFND----------SVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRF----------------SVHGTKFD-KDIWSRELNPVLNRW-KILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPE--EPFDYMRILILKAKAVEKWAEL---SEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRD----SNSIVLLPPVSV-GWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQD-KWIQSGVALF 12983
V ++ +W F +++ +Q Q+ ++ I++ K + + F + W+ KP +G DA+Q+++ + + L + N+ K E +++ E + E +D+ + +WS+ + T + ++ WLS + R L Q E + A++ + RL +K I Y + ++ ++ + L + HW ++ + L + L L+L + D + ++ +K++ AQGE+ + E ++++ L+ Y N +I+ W D+ ++V ++ + ++K SPYY+ F+++A WE KL ++ +QR+WVYLE IF +A LP E SRF+ + +F +M V ++ +V+ + ++ ++ L + D L + QKAL EYLE +R+ FPRFYF+GD+DLLEI+G S N ++ H KK+F G+ + N++ I+ + S +GE V N V ++ WL + +M+ TL+ L+ A+QD++ A DKY +QI+ L+ I ++ E L + + K + + L + +++ ADS + KL+ LI + VH + +LL+ S ++WL ++RFY Q Q I M +A F Y +EY G +LV TPLTD+CYLT+TQ + LGG+P+GPAGTGKTESVKALG+ GR VLVFNCDE D ++MGRIF+GL + G+WGCFDEFNRLEE +LSA S QIQ IQ+ +K ++ + L+ ++V V + AIFIT+NP GY GR LPDNLK+LFR +AM+ PD LIAEV+L S GF++A++L K+V F L E L+ Q HYD+GLRALK+VL A N+ + K +MK +G++ I+ +V ++ E ++++Q++ + KL D SL+ DVFPN+ E L I +V +E +V +G + K+L++Y+ G+++VGPSGSGKST WK L AL + G +V++PKAI + L G +D +TREW+DG+ T+ R+++ + EI + WII DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV +FE DL A+ AT+ SR+ I L D ++ K++E L ++ L FF S D I R E+ + ++ T LS+L ++ N+A +V ++ G+ R +V +T P +++Y N N++ E + S D I+ P T D R+ WL +P +L GP G GK++ L + L ++V L+ S+ TTP +L+ + C + G V P + + L+L+ +INLP +D +GT ++ISFL+Q++ +KGFY S+ +V L+ +Q V + N + GR LS RF V + + YP + L IY + + +L RL+P + + L N M+E Y + +FT D HY+++P ++T+WV + P+ D+ V L+ + ++E++R+FQDRLV R+ W+ E D + F E K + E L++ + L + E D+ ++LF EV D+V ++DR+ +P G +LL G SG G+ T S V+ M+ + + K+H Y + F DL+ L+ +G + E I +L++ L+ +LE +N+LLA+GEVPGL+ +E ++ K+ A G L +F ++ LH++ M+ S ++PA F C + W WS ++ ++ ++ E+ + + S P T D + + + +H T + T RHY++FI ++++Y +K++++E +Q H+ VG+ KI+E E V E++ A + + L K A+ LK++ Q A ++K + +++ ++ ++ V + +++ + +LA +EP V A+ AVS IK L+E+R++ PP V++ LE V ++ T W ++R L K I + +IT + R +++ D ++ + RAS+A P+ W A ++Y+ L+++ PL E + Q NL +A K+ KDL V +++++A Y++++ + + A ++ +L+N + + L+ L E ERW +++S + LL+AA + Y + R W + R ++L+ E+L W+ L +D+L ENA+++ + P +IDPS AT +L N + +K+ + D +F LE ++RFG L++Q+V+ +P+L P+L +L G R ++ LGD+ ID +P F +FL+TR+P + PPD + V+ VNFT T++ L+ Q L ++ +P ++E++++LL+ + + ++ L ++E+SLLQ L +A G IL++ ++ +L K+ + I+Q ++E+ K+ ++ +LPL+ S+++F + L++++ +Y++SL FL +F L + E TD + R + L ++ YE V R + DRL FAL M C+ L E L F+ + N T + + A++ +++ LA +P L V +I + W Q S E+ +PQ +L S ++L+IQA RPDR+ +A VL + + ++ + + + N P L+ PG D S + +L+ + +++ + +A+G QA+ +N+ + G W+ LKN+HL WL LEK+++SL+PH FRL++T E + LL++ +E PPG++ NLLR++ + KT S RA F LAWFHAI+QER ++P GW K YEF+ +DLR + LD I + + W + L +I+GG++DN FD R+L+S++K+ F + V+G+ I +P + +L I L+D +PS+ LP+N ++ + ++ +L +Q+ S G D + W + L+ W ++L + L ++K ++ + P+ + + E + +L++ V L + + +G + T +++ L+ G P W +++ P ++ + + ++K ++L + EL + LG L +P+ ++ A RQ A+ S++EL + G N + L ++G +C + +++I++ PV++ W+ + S+ ++LP+Y + R +++ +D+ +GQ+ + + GVA+
Sbjct: 1201 VDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKP------TGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDL---RGVWSELSKVWTQIDETREKPWLSVQPRK------LRQQLEAMM-AQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRV--NWVLSDLSLGQVWDV--NLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINY----QNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFRDGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLG-NVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNP---GYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFVGVIKPAKDKEEEVSPSLQVQRDIALLLLPFF--SADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAPIIDYEVNMSGDWVPWSNKVPVIEVETHKVASPD-------IVVP---TLDTVRHESLLYTWLAE--HKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAML-RLMP-----ALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPL--DSLPVEGLVRLWAHEALRLFQDRLVDDSERR-------------WTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCPLVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVSSIKKKHLAEVRSMANPPAVVKLALESVCELLNESATDWKAIRGILVKDSFISSIVNLETDKITDDVREKMKSKYLSNPD-YNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASA-KETKDL---VEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLM---CKIHLKGTSESNLDAEFNFFLRSREGLLANPTPVEGLSAEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQ---QSSPEQVVPQLWDESKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAE--QNKQISSIAIGSAEGFNQAERAINM---ACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPS-ERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQLEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTV------ENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGW-KRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGA--------QCKNNELLLASTIMMDLPVTILKWIKISSEPRISK---LTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAVL 4632 HSP 2 Score: 76.2554 bits (186), Expect = 8.284e-13 Identity = 87/428 (20.33%), Postives = 176/428 (41.12%), Query Frame = 3
Query: 780 NPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKL-------IKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQIL-----PHRE-----------RQEFKIEEAFKYFLNILPLAYNPYTE-----------PIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETK------NFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGL-LYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFY 1931
N YP R L+E I+ +L + + L + + + Q E+ S W D DKL +K+ ++L W Q R+ + R HEQ+ ++ P + +Q + ++ A + + LAY E W+ AVK++ I+ ET I L+ + +A+ ++ R+F R+N L RP I + + + L+ ++ + L E F +S+ ++ ++ I+W++Q++ +L L +VL G+E ++ K +F ++S + F +W +++ R + + G ++ + + + L L VN+ ++ L +EVR + LG+ + +++ A + Y A+ L + + Y
Sbjct: 369 NTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVS-----PAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPTKPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLR---DQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGK--GWETHIEGQKLKADGDSFRAKLSI--SDVFHEWARKVQER--NFGSTGRIFTIESTRSRIGRGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTY 782
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Fly
Match: Dhc64C (gene:FBgn0261797 transcript:FBtr0073359) HSP 1 Score: 1381.31 bits (3574), Expect = 0.000e+0 Identity = 1017/3531 (28.80%), Postives = 1776/3531 (50.30%), Query Frame = 3
Query: 3087 VSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQME--------PEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRL---------QKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITS--EVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINA-----DKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTF----IVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFY----QKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQE------ITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANL----LEMHKSKMKTQGNDTIE--NVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHK------KMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKI-GQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQ-EI--QSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATI-----------------------SRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHL-----LSTYLDDFFYKSLDWIAKRN-EFTISTSNVG--TVYNGLSNLKAIKNKAHFSV---------------------------CLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEK------QNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESER-LILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY-DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAV-SLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX-XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQN---SAKP--KTQLTGSDNLNSYFLDLHDTCPVEFS------------TSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRG-IQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENE----QNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMR------KFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTS---EISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFT--GTFISDKSD--RNITVPKWIDADRTVAISNLASAMP----ELWSVLNIKDDDLWHQFAKSSECEREIPQ------SLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHL--SPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQG----QADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSN--------RNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFND----------SVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRF----------------SVHGTKFD-KDIWSRELNPVLNRW-KILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPE--EPFDYMRILILKAKAVEKWAEL---SEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRD----SNSIVLLPPVSV-GWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQD-KWIQSGVALF 12983
V ++ +W F +++ +Q Q+ ++ I++ K + + F + W+ KP +G DA+Q+++ + + L + N+ K E +++ E + E +D+ + +WS+ + T + ++ WLS + R L Q E + A++ + RL +K I Y + ++ ++ + L + HW ++ + L + L L+L + D + ++ +K++ AQGE+ + E ++++ L+ Y N +I+ W D+ ++V ++ + ++K SPYY+ F+++A WE KL ++ +QR+WVYLE IF +A LP E SRF+ + +F +M V ++ +V+ + ++ ++ L + D L + QKAL EYLE +R+ FPRFYF+GD+DLLEI+G S N ++ H KK+F G+ + N++ I+ + S +GE V N V ++ WL + +M+ TL+ L+ A+QD++ A DKY +QI+ L+ I ++ E L + + K + + L + +++ ADS + KL+ LI + VH + +LL+ S ++WL ++RFY Q Q I M +A F Y +EY G +LV TPLTD+CYLT+TQ + LGG+P+GPAGTGKTESVKALG+ GR VLVFNCDE D ++MGRIF+GL + G+WGCFDEFNRLEE +LSA S QIQ IQ+ +K ++ + L+ ++V V + AIFIT+NP GY GR LPDNLK+LFR +AM+ PD LIAEV+L S GF++A++L K+V F L E L+ Q HYD+GLRALK+VL A N+ + K +MK +G++ I+ +V ++ E ++++Q++ + KL D SL+ DVFPN+ E L I +V +E +V +G + K+L++Y+ G+++VGPSGSGKST WK L AL + G +V++PKAI + L G +D +TREW+DG+ T+ R+++ + EI + WII DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV +FE DL A+ AT+ SR+ I L D ++ K++E L ++ L FF S D I R E+ + ++ T LS+L ++ N+A +V ++ G+ R +V +T P +++Y N N++ E + S D I+ P T D R+ WL +P +L GP G GK++ L + L ++V L+ S+ TTP +L+ + C + G V P + + L+L+ +INLP +D +GT ++ISFL+Q++ +KGFY S+ +V L+ +Q V + N + GR LS RF V + + YP + L IY + + +L RL+P + + L N M+E Y + +FT D HY+++P ++T+WV + P+ D+ V L+ + ++E++R+FQDRLV R+ W+ E D + F E K + E L++ + L + E D+ ++LF EV D+V ++DR+ +P G +LL G SG G+ T S V+ M+ + + K+H Y + F DL+ L+ +G + E I +L++ L+ +LE +N+LLA+GEVPGL+ +E ++ K+ A G L +F ++ LH++ M+ S ++PA F C + W WS ++ ++ ++ E+ + + S P T D + + + +H T + T RHY++FI ++++Y +K++++E +Q H+ VG+ KI+E E V E++ A + + L K A+ LK++ Q A ++K + +++ ++ ++ V + +++ + +LA +EP V A+ AV I+ L E+R + PP V++ LE + L++G T W S+R + + I + F IT + R +++ D ++ + RAS+A P+ W A ++Y+ L+++ PL E + Q NL +A K+ KDL V +++++A Y++++ + + A ++ +L+N + + L+ L E ERW +++S + LL+AA + Y + R W + R ++L+ E+L W+ L +D+L ENA+++ + P +IDPS AT +L N + +K+ + D +F LE ++RFG L++Q+V+ +P+L P+L +L G R ++ LGD+ ID +P F +FL+TR+P + PPD + V+ VNFT T++ L+ Q L ++ +P ++E++++LL+ + + ++ L ++E+SLLQ L +A G IL++ ++ +L K+ + I+Q ++E+ K+ ++ +LPL+ S+++F + L++++ +Y++SL FL +F L + E TD + R + L ++ YE V R + DRL FAL M C+ L E L F+ + N T + + A++ +++ LA +P L V +I + W Q S E+ +PQ +L S ++L+IQA RPDR+ +A VL + + ++ + + + N P L+ PG D S + +L+ + +++ + +A+G QA+ +N+ + G W+ LKN+HL WL LEK+++SL+PH FRL++T E + LL++ +E PPG++ NLLR++ + KT S RA F LAWFHAI+QER ++P GW K YEF+ +DLR + LD I + + W + L +I+GG++DN FD R+L+S++K+ F + V+G+ I +P + +L I L+D +PS+ LP+N ++ + ++ +L +Q+ S G D + W + L+ W ++L + L ++K ++ + P+ + + E + +L++ V L + + +G + T +++ L+ G P W +++ P ++ + + ++K ++L + EL + LG L +P+ ++ A RQ A+ S++EL + G N + L ++G +C + +++I++ PV++ W+ + S+ ++LP+Y + R +++ +D+ +GQ+ + + GVA+
Sbjct: 1201 VDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKP------TGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDL---RGVWSELSKVWTQIDETREKPWLSVQPRK------LRQQLEAMM-AQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRV--NWVLSDLSLGQVWDV--NLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINY----QNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFRDGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLG-NVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNP---GYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFVGVIKPAKDKEEEVSPSLQVQRDIALLLLPFF--SADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAPIIDYEVNMSGDWVPWSNKVPVIEVETHKVASPD-------IVVP---TLDTVRHESLLYTWLAE--HKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAML-RLMP-----ALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPL--DSLPVEGLVRLWAHEALRLFQDRLVDDSERR-------------WTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCPLVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQLVEVRTMANPPSVVKLALESICLLLGENATDWKSIRAVIMRENFINSIVSNFGTENITDDVREKMKSKYLSNPD-YNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASA-KETKDL---VEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLM---CKIHLKGTSESNLDAEFNFFLRSREGLLANPTPVEGLSAEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQ---QSSPEQVVPQLWDESKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAE--QNKQISSIAIGSAEGFNQAERAINM---ACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPS-ERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQLEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTV------ENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGW-KRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGA--------QCKNNELLLASTIMMDLPVTILKWIKISSEPRISK---LTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAVL 4633 HSP 2 Score: 76.6406 bits (187), Expect = 7.878e-13 Identity = 87/428 (20.33%), Postives = 176/428 (41.12%), Query Frame = 3
Query: 780 NPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKL-------IKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQIL-----PHRE-----------RQEFKIEEAFKYFLNILPLAYNPYTE-----------PIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETK------NFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGL-LYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFY 1931
N YP R L+E I+ +L + + L + + + Q E+ S W D DKL +K+ ++L W Q R+ + R HEQ+ ++ P + +Q + ++ A + + LAY E W+ AVK++ I+ ET I L+ + +A+ ++ R+F R+N L RP I + + + L+ ++ + L E F +S+ ++ ++ I+W++Q++ +L L +VL G+E ++ K +F ++S + F +W +++ R + + G ++ + + + L L VN+ ++ L +EVR + LG+ + +++ A + Y A+ L + + Y
Sbjct: 369 NTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVS-----PAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPTKPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLR---DQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGK--GWETHIEGQKLKADGDSFRAKLSI--SDVFHEWARKVQER--NFGSTGRIFTIESTRSRIGRGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTY 782
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Fly
Match: Dhc64C (gene:FBgn0261797 transcript:FBtr0332747) HSP 1 Score: 1380.93 bits (3573), Expect = 0.000e+0 Identity = 1016/3530 (28.78%), Postives = 1774/3530 (50.25%), Query Frame = 3
Query: 3087 VSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQME--------PEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRL---------QKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITS--EVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINA-----DKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTF----IVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFY----QKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQE------ITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANL----LEMHKSKMKTQGNDTIE--NVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHK------KMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKI-GQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQ-EI--QSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATI-----------------------SRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHL-----LSTYLDDFFYKSLDWIAKRN-EFTISTSNVG--TVYNGLSNLKAIKNKAHFSV---------------------------CLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEK------QNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESER-LILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY-DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX-XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQN---SAKP--KTQLTGSDNLNSYFLDLHDTCPVEFS------------TSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRG-IQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENE----QNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMR------KFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTS---EISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFT--GTFISDKSD--RNITVPKWIDADRTVAISNLASAMP----ELWSVLNIKDDDLWHQFAKSSECEREIPQ------SLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHL--SPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQG----QADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSN--------RNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFND----------SVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRF----------------SVHGTKFD-KDIWSRELNPVLNRW-KILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPE--EPFDYMRILILKAKAVEKWAEL---SEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRD----SNSIVLLPPVSV-GWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQD-KWIQSGVALF 12983
V ++ +W F +++ +Q Q+ ++ I++ K + + F + W+ KP +G DA+Q+++ + + L + N+ K E +++ E + E +D+ + +WS+ + T + ++ WLS + R L Q E + A++ + RL +K I Y + ++ ++ + L + HW ++ + L + L L+L + D + ++ +K++ AQGE+ + E ++++ L+ Y N +I+ W D+ ++V ++ + ++K SPYY+ F+++A WE KL ++ +QR+WVYLE IF +A LP E SRF+ + +F +M V ++ +V+ + ++ ++ L + D L + QKAL EYLE +R+ FPRFYF+GD+DLLEI+G S N ++ H KK+F G+ + N++ I+ + S +GE V N V ++ WL + +M+ TL+ L+ A+QD++ A DKY +QI+ L+ I ++ E L + + K + + L + +++ ADS + KL+ LI + VH + +LL+ S ++WL ++RFY Q Q I M +A F Y +EY G +LV TPLTD+CYLT+TQ + LGG+P+GPAGTGKTESVKALG+ GR VLVFNCDE D ++MGRIF+GL + G+WGCFDEFNRLEE +LSA S QIQ IQ+ +K ++ + L+ ++V V + AIFIT+NP GY GR LPDNLK+LFR +AM+ PD LIAEV+L S GF++A++L K+V F L E L+ Q HYD+GLRALK+VL A N+ + K +MK +G++ I+ +V ++ E ++++Q++ + KL D SL+ DVFPN+ E L I +V +E +V +G + K+L++Y+ G+++VGPSGSGKST WK L AL + G +V++PKAI + L G +D +TREW+DG+ T+ R+++ + EI + WII DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV +FE DL A+ AT+ SR+ I L D ++ K++E L ++ L FF S D I R E+ + ++ T LS+L ++ N+A +V ++ G+ R +V +T P +++Y N N++ E + S D I+ P T D R+ WL +P +L GP G GK++ L + L ++V L+ S+ TTP +L+ + C + G V P + + L+L+ +INLP +D +GT ++ISFL+Q++ +KGFY S+ +V L+ +Q V + N + GR LS RF V + + YP + L IY + + +L RL+P + + L N M+E Y + +FT D HY+++P ++T+WV + P+ S L+ + ++E++R+FQDRLV R+ W+ E D + F E K + E L++ + L + E D+ ++LF EV D+V ++DR+ +P G +LL G SG G+ T S V+ M+ + + K+H Y + F DL+ L+ +G + E I +L++ L+ +LE +N+LLA+GEVPGL+ +E ++ K+ A G L +F ++ LH++ M+ S ++PA F C + W WS ++ ++ ++ E+ + + S P T D + + + +H T + T RHY++FI ++++Y +K++++E +Q H+ VG+ KI+E E V E++ A + + L K A+ LK++ Q A ++K + +++ ++ ++ V + +++ + +LA +EP V A+ AV I+ L E+R + PP V++ LE + L++G T W S+R + + I + F IT + R +++ D ++ + RAS+A P+ W A ++Y+ L+++ PL E + Q NL +A K+ KDL V +++++A Y++++ + + A ++ +L+N + + L+ L E ERW +++S + LL+AA + Y + R W + R ++L+ E+L W+ L +D+L ENA+++ + P +IDPS AT +L N + +K+ + D +F LE ++RFG L++Q+V+ +P+L P+L +L G R ++ LGD+ ID +P F +FL+TR+P + PPD + V+ VNFT T++ L+ Q L ++ +P ++E++++LL+ + + ++ L ++E+SLLQ L +A G IL++ ++ +L K+ + I+Q ++E+ K+ ++ +LPL+ S+++F + L++++ +Y++SL FL +F L + E TD + R + L ++ YE V R + DRL FAL M C+ L E L F+ + N T + + A++ +++ LA +P L V +I + W Q S E+ +PQ +L S ++L+IQA RPDR+ +A VL + + ++ + + + N P L+ PG D S + +L+ + +++ + +A+G QA+ +N+ + G W+ LKN+HL WL LEK+++SL+PH FRL++T E + LL++ +E PPG++ NLLR++ + KT S RA F LAWFHAI+QER ++P GW K YEF+ +DLR + LD I + + W + L +I+GG++DN FD R+L+S++K+ F + V+G+ I +P + +L I L+D +PS+ LP+N ++ + ++ +L +Q+ S G D + W + L+ W ++L + L ++K ++ + P+ + + E + +L++ V L + + +G + T +++ L+ G P W +++ P ++ + + ++K ++L + EL + LG L +P+ ++ A RQ A+ S++EL + G N + L ++G +C + +++I++ PV++ W+ + S+ ++LP+Y + R +++ +D+ +GQ+ + + GVA+
Sbjct: 1214 VDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKP------TGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDL---RGVWSELSKVWTQIDETREKPWLSVQPRK------LRQQLEAMM-AQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRV--NWVLSDLSLGQVWDV--NLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINY----QNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFRDGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLG-NVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNP---GYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFVGVIKPAKDKEEEVSPSLQVQRDIALLLLPFF--SADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAPIIDYEVNMSGDWVPWSNKVPVIEVETHKVASPD-------IVVP---TLDTVRHESLLYTWLAE--HKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAML-RLMP-----ALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPLDSLPVE-GLVRLWAHEALRLFQDRLVDDSERR-------------WTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCPLVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQLVEVRTMANPPSVVKLALESICLLLGENATDWKSIRAVIMRENFINSIVSNFGTENITDDVREKMKSKYLSNPD-YNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASA-KETKDL---VEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLM---CKIHLKGTSESNLDAEFNFFLRSREGLLANPTPVEGLSAEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQ---QSSPEQVVPQLWDESKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAE--QNKQISSIAIGSAEGFNQAERAINM---ACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPS-ERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQLEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTV------ENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGW-KRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGA--------QCKNNELLLASTIMMDLPVTILKWIKISSEPRISK---LTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAVL 4646 HSP 2 Score: 76.6406 bits (187), Expect = 7.620e-13 Identity = 87/428 (20.33%), Postives = 176/428 (41.12%), Query Frame = 3
Query: 780 NPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKL-------IKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQIL-----PHRE-----------RQEFKIEEAFKYFLNILPLAYNPYTE-----------PIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETK------NFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGL-LYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFY 1931
N YP R L+E I+ +L + + L + + + Q E+ S W D DKL +K+ ++L W Q R+ + R HEQ+ ++ P + +Q + ++ A + + LAY E W+ AVK++ I+ ET I L+ + +A+ ++ R+F R+N L RP I + + + L+ ++ + L E F +S+ ++ ++ I+W++Q++ +L L +VL G+E ++ K +F ++S + F +W +++ R + + G ++ + + + L L VN+ ++ L +EVR + LG+ + +++ A + Y A+ L + + Y
Sbjct: 369 NTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVS-----PAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPTKPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLR---DQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGK--GWETHIEGQKLKADGDSFRAKLSI--SDVFHEWARKVQER--NFGSTGRIFTIESTRSRIGRGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTY 782
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Zebrafish
Match: DYNC2H1 (dynein cytoplasmic 2 heavy chain 1 [Source:NCBI gene;Acc:100332402]) HSP 1 Score: 4329.63 bits (11228), Expect = 0.000e+0 Identity = 2234/4333 (51.56%), Postives = 3016/4333 (69.61%), Query Frame = 3
Query: 96 MSKIEDQRKDTIFLITKSHFPNQNSKFVNEEC--LDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPP--TKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRN-AEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYE-----CEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEV--QDSLNDVWFVTWG-SREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGN----FYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNII--KASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLK 12989
M+ D + L T ++ + ++ C LD F D+ + +L V + FSN+L D LVF K P +++ +N+ I+V+++ E+PIS+LY ++ +Y P+LL D D K+Q L+S+LE GLGS++R +K S + I + DE FW D + + R + ++ + S SL E +EN ++D+W+ P YP++RM LM++I L R +Q +L+ L WED Y V+E L + VC W+ C+ L + WK+Y PH+W + + S Q RL E+ +R+V E++ ++L +Q+ ++ F + P+ YNPYTEP+W+ AV +F R I PAE +LK + + + PQQLL++FQ++ DLI R IS L ERETLL +L+ + K LR DF H + K P +N + ++ IVW +QL K+ + L + +L DL GF+ L+ + + E++ ++ QEQFE W +++ L D + + R+MEL DG L + YSDRLV+L+REVR LS LG+ I + AA+ +KFY +A+ILKQVA FYNTI+ QMIP Q+ MML A+ FE+++KS K + + W NP+EL Q+I KLQ A+ + ++NR LRK H +K+V LMG+DLLRQQQ+WKD L ++R +E+Q + W++H +HQLYKALE+QY +GLEALN+NLPEI +DLV++QGRLQF P FEE+++KY++EMK+FI++PNQFKG++++ G + IF +IERNA+GF+ + KAE LF RLS L+KFK+W+++G +D+E V++H + D+E+NFKA+K KGKEAE+LP+ K+DCITVNC P+++SVD LIQ +FDALL SLR++I+G I +D+++ +++ LS RP++IDEI EA H++ + + Q ++E+ N LLR+VAGGG+DT+S L+ KWDKFELMMES Q+M++EQ+EVMK N+ SR + +QQD+ KF RW LKPG DI++SG +A VQ I++++ E EL +T L +DCEHF + + TL + +D+ MW +EE+ +GL+ +A+ DW+SFRS+ ++FEEFL W ++LR E ++M+++LQKE+D YK ++P+LK++RGE LSQ+HWL++FRL+++PRG TLE L R +L A II +K+LN +AQ EV+IREA+RELELWGAGA F L +Y D+Q S+ +IK+WRD+++QVGDN+CLLQSLKDSPYY FQDK ++WE +LADLDEYL NLN IQRKWVYL+PIFG+ ALP+E++RF+RVD+DF +R L + S S + L + QL GI V+F++ Q I MKSL+GE V L N + I+++VE WL L EMK TL L + + N ++ ++PSQ+LCL+E I FTA E + + ++ L+++L KL YT+ S + V +KLK+LILD +HNI ++ L + S +W W KQLRFY + DQ C IQMVDA+F YTYEYQGNA KLVHTPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG LFGRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQ+ +KN LL + V++D NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAM+ PDN+LIAEVIL S+GFK K LGRKLVAIFNL+RELLTPQQHYDWGLRALKTVL+G +LL++ + N+ ++ E+ L+VQALR+NT+SKLT+AD F++L++DVFP +D K++EY+ L SA+ V +E ++ + Q KK +E+YEQLRQRMGVV+VGPSG+GKST+W++LR AL K G+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQE+ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TDV SLV SWLK++DE + L +L+D+F+++L+W+ K+++F + TS VGTV NGLS+L ++ + F + LI+GLGGNL R+ FA V E P+ K L+ Y+++ RL Y + CEEELS D L P+I T D QR+L F WL+++ +QPF+L GPEGCGK ++L F +L+S QV+ +HCSAQT+ HVLQKL C++I+SNTGRVYRPK+ ERL+LYLKDINLPK DKWGTS LI+FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ ++GR +L++RFTSIVR+C+I YP ++QL +Y+AYLKPVL+R + P WS + K+ LA ++++VY Q+K+KF+VDD+SHYLFTP LT+WVL+LLRYDL NT + L M ++ D++ + N +H+ +S S +DV+FVTW S E ++ G P P G+ L +L + L + I +G++ Y R+ R+LDI+LF EV D ++++DRVLT PGGS+LLAG+SGVGRRT + +VSHMH L +PK+ R Y LK FK+DLK+ + +A V+G+ +VLLLEDHQF+ P +LE++NSLL+SGEVPGLY+TEELEP+L SLKD A++ G G + NYF+ R++ LH++LIMDC+N +F INC+SNPA ++ CSVQW+E WS SM KIP ML+++I +E ++ Q K K + L FL +H++C +T Y+NF+++Y IY K+ E+ +Q H+Q G+ K++EAK +V ELK +AAEQS LL KQ EAD AL++IT+ MQ A+++K EMEK+ + E + +RK ID+EL ++P V +A+ AV +IKS LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++EEI TFDAR IT E R VEELL R K SFDPKNAKRAS AAAPLAAWVKANV+YS+ LEKI PL+ E L NL E + LEK ++ V + V ++ F+ T +AAKLE E+ A ETISAAE L+ +L+ E RW Q+ E++ EL L ++ L+AA + Y+P++PEDQR+ + WM +GL+KFD+R FL +E EQL WK EGL SD+LSMENALVILQ PFLIDPSS AT WL+ H K +LE++NQQD+NF TVLEL+VRFGKTLIIQE+DG+EPVLYPLLR DLI+QGPR VVQ+GDK++DYN DF+LFLATRNP P +PPDA ++++ VNFTTT+AGL+GQLLALT+Q KP+LE +KT LLQ+EE+ KI+L+++EESLL+ LA A GNIL NK+L+ SLN+TK SS I QSL +S +LQ SLD+ERDA+LPLAE S ++FVI+DLSKINNMYRFSL SFLRLF RAL T + S + +R ++L + L+ +VYEY+CRS+FK+D+LMFALH P+LF+ EW++FTG + D K+D ++ P WID +R +A++ + S P L+ L + D DLW F +SS CE+EIP + K+SLFQ++L++QALRPDRLQSA++ F L +K LSP +NL +YE ET+ EP+L+IIS GADPSQ+LQEL+ ++G E Y++VAMGQGQAD+ L L +C ++GDWLCLKNLHLVT+WLP+LEKELNS+KP FRLW+TAE H F+ ILLQSSLKITYEAPPG+K NL R+Y++WS + ISK G RA +LF LAWFHA+ QERRN+IPQGWTKFYEFS++DLRAG EI+D++ + + QW F+ GL EN I+GGR+DN D+ VL SY++++FN +++ S F +I LP++ S DY +++ L + + PSFF LP NI+RSSQRIISSQVI QLRIL R G+KFD++IWS L+PVLN WK LNQG ++I K +LP S SP+ +F+QLE++N+++LV+ +H SL SLSKV++G+ LLT +V L+ LL + P W +WEGPE+P Y+R ++ +A A++ W E +E+ LLS +LDL ELFHPDTFLNALRQ TAR + SMD LKFV W G AK VK+G L +EGC FDG ++E + DS S+ +PP + W+ + YS D+ ISLP+Y R +VT + +PC +G D WIQSG ALFLK
Sbjct: 1 MAPGTDDPRKLFILTTAGNYFSLDTAASLSSCRPLDNFLDDGNEFLLSVTRQSEELQFSNKLENMDGDGRVLVFFKPHPCVVSEENLQRCILVSSMLESPISTLYQALRQVYSPVLLQDDKWSQSFDSKLQSLLSDLEIGLGSVLRHSDTKGSGKRN-------IMTPLDEFSFWADVSRSGQKSSERDRATHFCELFTTIEKDYSNLDSFSLVEVLDLIENTREAVDDVWKQNEHTP-YPETRMIRLMDVIGGALGRFVQRKLSDLRLWEDPYFTVREGLKGGVAVCEQWVAACEHLTGQVWKRYAPHQWTGEKHRPQGLHSLAQ-RLEEVVQVRSVCEKLQRLLSG-GKQQISAARVYQPFTGLNPIHYNPYTEPLWRAAVSQFDRLIAPAEQEAAGKLKTFIID--AQDSPQQLLQVFQKHRDLIKRATISKELQPERETLLTRLLDYNKGLRADFESRCHGTPGEKTGPLAGRNLPEVVNNIVWVRQLLLKVEDSLKMADALLSDLSGFQPLLRFSDDLQEQLRSYEQEQFEDWTRDLLSGLSDPKSG-----ISNRVMELDHMDGKLKIQYSDRLVSLLREVRQLSALGFTIPAKIQQAANTAEKFYRQAIILKQVAHFYNTIDQQMIPSQRPMMLGCALAFEQVIKSRDEGGKLQ--MTWENPKELEQYISKLQSAAERLSTENRKLRKWHTDFTDKVVGLMGVDLLRQQQRWKDGLQDLRAGFATLESQGFGAGDMRAWRQHWNHQLYKALEHQYQVGLEALNKNLPEINIDLVFKQGRLQFRPAFEEVRAKYYREMKRFISIPNQFKGVSET--GEEPIFTRMIERNASGFLTIFSKAEHLFSRLSHLLDKFKDWVVVGQVDVEVLVEKHLHSVQDWERNFKALKAKGKEAERLPSSEKVDCITVNCEPVRVSVDDLIQRLFDALLASLRRSIQGHIQVIDSFVNGAMETLSLRPESIDEIGEANAKHSQLQTQKPEVLPQFQQAEEKNRLLRSVAGGGLDTISSLRAKWDKFELMMESHQLMIREQVEVMKGNVESRVQVYQQDLQKFRARWDQLKPGNDIIESGDHEALQRCVQIIRERQAEFSELENTRTKLMEDCEHFNLSSPDGTLASDTLRDLQDCSQMWELYEEFHSGLEEIAQHDWISFRSKTHVFEEFLFAWHDRLRKLEEHSSMSVKLQKEVDRYKAVVPVLKYVRGEHLSQEHWLDLFRLISLPRGSTLETLQFRDLLRVADNIIDKTLELKDLNSRAQAEVSIREALRELELWGAGASFTLTDYTDTQGCSLPVIKDWRDVVNQVGDNRCLLQSLKDSPYYLRFQDKVSLWETRLADLDEYLHNLNTIQRKWVYLQPIFGRGALPREQARFQRVDQDF----------SRFLKIASDSAVLMQLGSSFHQL---------------------------------------------------GISSVEFDQSFQSITAMKSLEGETVPLINTICISNDVEVWLSALAAEMKNTLKHLLCECVNAGKKGN-----VDPTRFPSQVLCLAEQIEFTAAVEISIRQQSLHQLEQQLTAKLENYTSVDTSTDNTTESRVLQMKLKALILDVIHNISLVQSLREAQINSTDDWVWKKQLRFYLNA-DQSCSIQMVDADFRYTYEYQGNAAKLVHTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQDIQNSLKNHRSTCQLLNKEVDLDPNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMTSPDNELIAEVILYSEGFKEGKALGRKLVAIFNLARELLTPQQHYDWGLRALKTVLRGCGSLLQLQR-----LNNNPLK-------ESGLVVQALRLNTMSKLTFADSSRFDALVRDVFPGVDFKDVEYETLKSALLAVYEEAHLEIIPSQLKKAVELYEQLRQRMGVVVVGPSGAGKSTLWRMLRAALGKTGRLVKQYTMNPKAMPRQQLLGHIDMDTREWSDGVLTSSARQVVREPQEVNSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSCASPATISRMGMIFLSDEDTDVGSLVKSWLKREDEDCRMNLENWLNDYFHRALEWVLKQSDFVVDTSLVGTVLNGLSHLSGVRERGEFIMGLIRGLGGNLTLKCRQDFAKEVLSWARESPPDPRKP--LDTYYDQASGRLCVYELQRGEGVCEEELS------DPHNL-PVIHTPDTQRSLHSFSPWLSANHRQPFLLVGPEGCGKGMLLRCAFSQLRSTQVSVVHCSAQTSSRHVLQKLQHTCLLISSNTGRVYRPKDCERLLLYLKDINLPKPDKWGTSNLIAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGAVGRHTLTSRFTSIVRICTIDYPDREQLQTVYSAYLKPVLQRTLGNDPTWSSSGKIHQLAGSLVQVYEQVKAKFSVDDHSHYLFTPCLLTEWVLNLLRYDLSAGELNTLNNSLTSPKTLYMSLYIDQIP-----------IQNILHTGFSCCCICVFSASDVYFVTWAASHEGRSPGQPLPPHGRKLARLNASDLSEIIHKGIVLYGRDNRELDILLFPEVLDYMSRVDRVLTSPGGSLLLAGRSGVGRRTATCVVSHMHGATLFTPKISRSYSLKHFKSDLKTVMHSAAVDGQQVVLLLEDHQFVHPSFLEMVNSLLSSGEVPGLYSTEELEPLLASLKDQASQDGFTGPVLNYFSHRVQQNLHVVLIMDCTNEHFTINCESNPALYRKCSVQWMESWSDSSMKKIPEMLLSRIEEDEKTEDKQR--KKKKSASVHTELYRSFLAIHESCREFGATPSQYLNFLQVYQSIYSSKRKELTHKQQHLQAGVAKLNEAKALVDELKRRAAEQSSLLKTKQAEADAALQEITTSMQNASDQKTEMEKIKERMAHEVSKIEERKKKIDEELREVQPLVDEAKQAVGNIKSESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREEIATFDARSITHEIRQSVEELLHRNKASFDPKNAKRASAAAAPLAAWVKANVQYSHVLEKIEPLQTEHAGLMENLRKTENRKNRLEKELNSVGEKVLELKEKFQCRTTEAAKLESEVSRAQETISAAEKLLQQLDGEHTRWTAQVDEISEELDTLPKRAQLSAAFITYLPAAPEDQRRSSLDHWMSSSGLQKFDLRHFLCSESEQLIWKSEGLPSDDLSMENALVILQSASCPFLIDPSSRATEWLQTHLKAHRLEVINQQDANFMTVLELAVRFGKTLIIQEMDGVEPVLYPLLRRDLIAQGPRYVVQIGDKVMDYNEDFRLFLATRNPSPFIPPDAASVITEVNFTTTRAGLRGQLLALTIQQEKPELESQKTKLLQQEEEKKIQLAQLEESLLETLATAQGNILENKELIESLNQTKASSALIQQSLSQSHRLQTSLDQERDAYLPLAETASKMYFVITDLSKINNMYRFSLASFLRLFHRALQTKQESESTDVRISTLESSLKNMVYEYICRSLFKADQLMFALHFVKGMSPELFQENEWDVFTGLVVGDMVRKTDSQKSLREQFPSWIDQERLMAVALIKSTFPVLYQSLCLSDADLWLTFLRSSCCEQEIPLPVAKKISLFQQMLVVQALRPDRLQSAMAVFASQALGMKQLSPPPLNLKHLYE-ETLETEPVLLIISAGADPSQELQELAGNIVGRENYHEVAMGQGQADVALQALRECVRSGDWLCLKNLHLVTAWLPLLEKELNSMKPKAGFRLWLTAEVHPKFTPILLQSSLKITYEAPPGLKKNLKRTYESWSAEQISKGGLLARAQSLFCLAWFHAVCQERRNYIPQGWTKFYEFSLSDLRAGFEIIDRLF-EGGKAFQWDFVDGLLEN-IYGGRIDNVCDLLVLRSYLQQFFNAQLLSQSRKKTHAFPAQIHLPNSCSIADYRVVVDALPEDDRPSFFGLPANIERSSQRIISSQVISQLRILSRPVAAGSKFDREIWSSALSPVLNLWKRLNQGSSLIHQKVTLPS----ESVGSPIFSFIQLEQFNAVRLVQSIHQSLASLSKVIRGTSLLTADVHKLATALLNQECPLSWQNKWEGPEDPMQYLRAVVSRALAIQGWVERAERGGLLSEMLDLSELFHPDTFLNALRQETARLMSCSMDSLKFVTTWRGQITEAKLQVKVGGLQLEGCSFDGNRLSESHHDSPSVSSVPPCHMAWIPVSAMGCYSPDECISLPVYSSAERVCVVTNVQLPC-AGDHDTWIQSGAALFLK 4203
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Zebrafish
Match: DYNC2H1 (dynein cytoplasmic 2 heavy chain 1 [Source:NCBI gene;Acc:100332402]) HSP 1 Score: 4316.15 bits (11193), Expect = 0.000e+0 Identity = 2231/4333 (51.49%), Postives = 3019/4333 (69.67%), Query Frame = 3
Query: 96 MSKIEDQRKDTIFLITKSHFPNQNSKFVNEEC--LDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPP--TKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRN-AEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYE-----CEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEV--QDSLNDVWFVTWG-SREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGN----FYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNII--KASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLK 12989
M+ D + L T ++ + ++ C LD F D+ + +L V + FSN+L D LVF K P +++ +N+ I+V+++ E+PIS+LY ++ +Y P+LL D D K+Q L+S+LE GLGS++R +K S + I + DE FW D + + R + ++ + S SL E +EN ++D+W+ P YP++RM LM++I L R +Q +L+ L WED Y V+E L + VC W+ C+ L + WK+Y PH+W + + S Q RL E+ +R+V E++ ++L +Q+ ++ F + P+ YNPYTEP+W+ AV +F R I PAE +LK + + + PQQLL++FQ++ DLI R IS L ERETLL +L+ + K LR DF H + K P +N + ++ IVW +QL K+ + L + +L DL GF+ L+ + + E++ ++ QEQFE W +++ L D + + R+MEL DG L + YSDRLV+L+REVR LS LG+ I + AA+ +KFY +A+ILKQVA FYNTI+ QMIP Q+ MML A+ FE+++KS K + + W NP+EL Q+I KLQ A+ + ++NR LRK H +K+V LMG+DLLRQQQ+WKD L ++R +E+Q + W++H +HQLYKALE+QY +GLEALN+NLPEI +DLV++QGRLQF P FEE+++KY++EMK+FI++PNQFKG++++ G + IF +IERNA+GF+ + KAE LF RLS L+KFK+W+++G +D+E V++H + D+E+NFKA+K KGKEAE+LP+ K+DCITVNC P+++SVD LIQ +FDALL SLR++I+G I +D+++ +++ LS RP++IDEI EA H++ + + Q ++E+ N LLR+VAGGG+DT+S L+ KWDKFELMMES Q+M++EQ+EVMK N+ SR + +QQD+ KF RW LKPG DI++SG +A VQ I++++ E EL +T L +DCEHF + + TL + +D+ MW +EE+ +GL+ +A+ DW+SFRS+ ++FEEFL W ++LR E ++M+++LQKE+D YK ++P+LK++RGE LSQ+HWL++FRL+++PRG TLE L R +L A II +K+LN +AQ EV+IREA+RELELWGAGA F L +Y D+Q S+ +IK+WRD+++QVGDN+CLLQSLKDSPYY FQDK ++WE +LADLDEYL NLN IQRKWVYL+PIFG+ ALP+E++RF+RV D + +N ++ +G+ L+ T + C + ++ Q + + +GI V+F++ Q I MKSL+GE V L N + I+++VE WL L EMK TL L + + N ++ ++PSQ+LCL+E I FTA E + + ++ L+++L KL YT+ S + V +KLK+LILD +HNI ++ L + S +W W KQLRFY + DQ C IQMVDA+F YTYEYQGNA KLVHTPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG LFGRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQ+ +KN LL + V++D NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAM+ PDN+LIAEVIL S+GFK K LGRKLVAIFNL+RELLTPQQHYDWGLRALKTVL+G +LL++ + N+ ++ E+ L+VQALR+NT+SKLT+AD F++L++DVFP +D K++EY+ L SA+ V +E ++ + Q KK +E+YEQLRQRMGVV+VGPSG+GKST+W++LR AL K G+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQE+ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TDV SLV SWLK++DE + L +L+D+F+++L+W+ K+++F + TS VGTV NGLS+L ++ + F + LI+GLGGNL R+ FA V E P+ K L+ Y+++ RL Y + CEEELS D L P+I T D QR+L F WL+++ +QPF+L GPEGCGK ++L F +L+S QV+ +HCSAQT+ HVLQKL C++I+SNTGRVYRPK+ ERL+LYLKDINLPK DKWGTS LI+FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ ++GR +L++RFTSIVR+C+I YP ++QL +Y+AYLKPVL+R + P WS + K+ LA ++++VY Q+K+KF+VDD+SHYLFTP LT+WVL+LLRYDL I+ Y++ +F R V+ L IH+ +S S +DV+FVTW S E ++ G P P G+ L +L + L + I +G++ Y R+ R+LDI+LF EV D ++++DRVLT PGGS+LLAG+SGVGRRT + +VSHMH L +PK+ R Y LK FK+DLK+ + +A V+G+ +VLLLEDHQF+ P +LE++NSLL+SGEVPGLY+TEELEP+L SLKD A++ G G + NYF+ R++ LH++LIMDC+N +F INC+SNPA ++ CSVQW+E WS SM KIP ML+++I +E ++ Q K L FL +H++C +T Y+NF+++Y IY K+ E+ +Q H+Q G+ K++EAK +V ELK +AAEQS LL KQ EAD AL++IT+ MQ A+++K EMEK+ + E + +RK ID+EL ++P V +A+ AV +IKS LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++EEI TFDAR IT E R VEELL R K SFDPKNAKRAS AAAPLAAWVKANV+YS+ LEKI PL+ E L NL E + LEK ++ V + V ++ F+ T +AAKLE E+ A ETISAAE L+ +L+ E RW Q+ E++ EL L ++ L+AA + Y+P++PEDQR+ + WM +GL+KFD+R FL +E EQL WK EGL SD+LSMENALVILQ PFLIDPSS AT WL+ H K +LE++NQQD+NF TVLEL+VRFGKTLIIQE+DG+EPVLYPLLR DLI+QGPR VVQ+GDK++DYN DF+LFLATRNP P +PPDA ++++ VNFTTT+AGL+GQLLALT+Q KP+LE +KT LLQ+EE+ KI+L+++EESLL+ LA A GNIL NK+L+ SLN+TK SS I QSL +S +LQ SLD+ERDA+LPLAE S ++FVI+DLSKINNMYRFSL SFLRLF RAL T + S + +R ++L + L+ +VYEY+CRS+FK+D+LMFALH P+LF+ EW++FTG + D K+D ++ P WID +R +A++ + S P L+ L + D DLW F +SS CE+EIP + K+SLFQ++L++QALRPDRLQSA++ F L +K LSP +NL +YE ET+ EP+L+IIS GADPSQ+LQEL+ ++G E Y++VAMGQGQAD+ L L +C ++GDWLCLKNLHLVT+WLP+LEKELNS+KP FRLW+TAE H F+ ILLQSSLKITYEAPPG+K NL R+Y++WS + ISK G RA +LF LAWFHA+ QERRN+IPQGWTKFYEFS++DLRAG EI+D++ + + QW F+ GL EN I+GGR+DN D+ VL SY++++FN +++ S F +I LP++ S DY +++ L + + PSFF LP NI+RSSQRIISSQVI QLRIL R G+KFD++IWS L+PVLN WK LNQG ++I K +LP S SP+ +F+QLE++N+++LV+ +H SL SLSKV++G+ LLT +V L+ LL + P W +WEGPE+P Y+R ++ +A A++ W E +E+ LLS +LDL ELFHPDTFLNALRQ TAR + SMD LKFV W G AK VK+G L +EGC FDG ++E + DS S+ +PP + W+ + YS D+ ISLP+Y R +VT + +PC +G D WIQSG ALFLK
Sbjct: 1 MAPGTDDPRKLFILTTAGNYFSLDTAASLSSCRPLDNFLDDGNEFLLSVTRQSEELQFSNKLENMDGDGRVLVFFKPHPCVVSEENLQRCILVSSMLESPISTLYQALRQVYSPVLLQDDKWSQSFDSKLQSLLSDLEIGLGSVLRHSDTKGSGKRN-------IMTPLDEFSFWADVSRSGQKSSERDRATHFCELFTTIEKDYSNLDSFSLVEVLDLIENTREAVDDVWKQNEHTP-YPETRMIRLMDVIGGALGRFVQRKLSDLRLWEDPYFTVREGLKGGVAVCEQWVAACEHLTGQVWKRYAPHQWTGEKHRPQGLHSLAQ-RLEEVVQVRSVCEKLQRLLSG-GKQQISAARVYQPFTGLNPIHYNPYTEPLWRAAVSQFDRLIAPAEQEAAGKLKTFIID--AQDSPQQLLQVFQKHRDLIKRATISKELQPERETLLTRLLDYNKGLRADFESRCHGTPGEKTGPLAGRNLPEVVNNIVWVRQLLLKVEDSLKMADALLSDLSGFQPLLRFSDDLQEQLRSYEQEQFEDWTRDLLSGLSDPKSG-----ISNRVMELDHMDGKLKIQYSDRLVSLLREVRQLSALGFTIPAKIQQAANTAEKFYRQAIILKQVAHFYNTIDQQMIPSQRPMMLGCALAFEQVIKSRDEGGKLQ--MTWENPKELEQYISKLQSAAERLSTENRKLRKWHTDFTDKVVGLMGVDLLRQQQRWKDGLQDLRAGFATLESQGFGAGDMRAWRQHWNHQLYKALEHQYQVGLEALNKNLPEINIDLVFKQGRLQFRPAFEEVRAKYYREMKRFISIPNQFKGVSET--GEEPIFTRMIERNASGFLTIFSKAEHLFSRLSHLLDKFKDWVVVGQVDVEVLVEKHLHSVQDWERNFKALKAKGKEAERLPSSEKVDCITVNCEPVRVSVDDLIQRLFDALLASLRRSIQGHIQVIDSFVNGAMETLSLRPESIDEIGEANAKHSQLQTQKPEVLPQFQQAEEKNRLLRSVAGGGLDTISSLRAKWDKFELMMESHQLMIREQVEVMKGNVESRVQVYQQDLQKFRARWDQLKPGNDIIESGDHEALQRCVQIIRERQAEFSELENTRTKLMEDCEHFNLSSPDGTLASDTLRDLQDCSQMWELYEEFHSGLEEIAQHDWISFRSKTHVFEEFLFAWHDRLRKLEEHSSMSVKLQKEVDRYKAVVPVLKYVRGEHLSQEHWLDLFRLISLPRGSTLETLQFRDLLRVADNIIDKTLELKDLNSRAQAEVSIREALRELELWGAGASFTLTDYTDTQGCSLPVIKDWRDVVNQVGDNRCLLQSLKDSPYYLRFQDKVSLWETRLADLDEYLHNLNTIQRKWVYLQPIFGRGALPREQARFQRV---------DQDFSNMLIH----TGVMVLIFTFVI----CNACFTHH---------------------VITQICHVWCL------CVKGISSVEFDQSFQSITAMKSLEGETVPLINTICISNDVEVWLSALAAEMKNTLKHLLCECVNAGKKGN-----VDPTRFPSQVLCLAEQIEFTAAVEISIRQQSLHQLEQQLTAKLENYTSVDTSTDNTTESRVLQMKLKALILDVIHNISLVQSLREAQINSTDDWVWKKQLRFYLNA-DQSCSIQMVDADFRYTYEYQGNAAKLVHTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQDIQNSLKNHRSTCQLLNKEVDLDPNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMTSPDNELIAEVILYSEGFKEGKALGRKLVAIFNLARELLTPQQHYDWGLRALKTVLRGCGSLLQLQR-----LNNNPLK-------ESGLVVQALRLNTMSKLTFADSSRFDALVRDVFPGVDFKDVEYETLKSALLAVYEEAHLEIIPSQLKKAVELYEQLRQRMGVVVVGPSGAGKSTLWRMLRAALGKTGRLVKQYTMNPKAMPRQQLLGHIDMDTREWSDGVLTSSARQVVREPQEVNSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSCASPATISRMGMIFLSDEDTDVGSLVKSWLKREDEDCRMNLENWLNDYFHRALEWVLKQSDFVVDTSLVGTVLNGLSHLSGVRERGEFIMGLIRGLGGNLTLKCRQDFAKEVLSWARESPPDPRKP--LDTYYDQASGRLCVYELQRGEGVCEEELS------DPHNL-PVIHTPDTQRSLHSFSPWLSANHRQPFLLVGPEGCGKGMLLRCAFSQLRSTQVSVVHCSAQTSSRHVLQKLQHTCLLISSNTGRVYRPKDCERLLLYLKDINLPKPDKWGTSNLIAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGAVGRHTLTSRFTSIVRICTIDYPDREQLQTVYSAYLKPVLQRTLGNDPTWSSSGKIHQLAGSLVQVYEQVKAKFSVDDHSHYLFTPCLLTEWVLNLLRYDLS-----------NILQYKASHVF--RCVN----------LLLVIHTGFSCCCICVFSASDVYFVTWAASHEGRSPGQPLPPHGRKLARLNASDLSEIIHKGIVLYGRDNRELDILLFPEVLDYMSRVDRVLTSPGGSLLLAGRSGVGRRTATCVVSHMHGATLFTPKISRSYSLKHFKSDLKTVMHSAAVDGQQVVLLLEDHQFVHPSFLEMVNSLLSSGEVPGLYSTEELEPLLASLKDQASQDGFTGPVLNYFSHRVQQNLHVVLIMDCTNEHFTINCESNPALYRKCSVQWMESWSDSSMKKIPEMLLSRIEEDEKTEDKQRKKKKSVH----TELYRSFLAIHESCREFGATPSQYLNFLQVYQSIYSSKRKELTHKQQHLQAGVAKLNEAKALVDELKRRAAEQSSLLKTKQAEADAALQEITTSMQNASDQKTEMEKIKERMAHEVSKIEERKKKIDEELREVQPLVDEAKQAVGNIKSESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREEIATFDARSITHEIRQSVEELLHRNKASFDPKNAKRASAAAAPLAAWVKANVQYSHVLEKIEPLQTEHAGLMENLRKTENRKNRLEKELNSVGEKVLELKEKFQCRTTEAAKLESEVSRAQETISAAEKLLQQLDGEHTRWTAQVDEISEELDTLPKRAQLSAAFITYLPAAPEDQRRSSLDHWMSSSGLQKFDLRHFLCSESEQLIWKSEGLPSDDLSMENALVILQSASCPFLIDPSSRATEWLQTHLKAHRLEVINQQDANFMTVLELAVRFGKTLIIQEMDGVEPVLYPLLRRDLIAQGPRYVVQIGDKVMDYNEDFRLFLATRNPSPFIPPDAASVITEVNFTTTRAGLRGQLLALTIQQEKPELESQKTKLLQQEEEKKIQLAQLEESLLETLATAQGNILENKELIESLNQTKASSALIQQSLSQSHRLQTSLDQERDAYLPLAETASKMYFVITDLSKINNMYRFSLASFLRLFHRALQTKQESESTDVRISTLESSLKNMVYEYICRSLFKADQLMFALHFVKGMSPELFQENEWDVFTGLVVGDMVRKTDSQKSLREQFPSWIDQERLMAVALIKSTFPVLYQSLCLSDADLWLTFLRSSCCEQEIPLPVAKKISLFQQMLVVQALRPDRLQSAMAVFASQALGMKQLSPPPLNLKHLYE-ETLETEPVLLIISAGADPSQELQELAGNIVGRENYHEVAMGQGQADVALQALRECVRSGDWLCLKNLHLVTAWLPLLEKELNSMKPKAGFRLWLTAEVHPKFTPILLQSSLKITYEAPPGLKKNLKRTYESWSAEQISKGGLLARAQSLFCLAWFHAVCQERRNYIPQGWTKFYEFSLSDLRAGFEIIDRLF-EGGKAFQWDFVDGLLEN-IYGGRIDNVCDLLVLRSYLQQFFNAQLLSQSRKKTHAFPAQIHLPNSCSIADYRVVVDALPEDDRPSFFGLPANIERSSQRIISSQVISQLRILSRPVAAGSKFDREIWSSALSPVLNLWKRLNQGSSLIHQKVTLPS----ESVGSPIFSFIQLEQFNAVRLVQSIHQSLASLSKVIRGTSLLTADVHKLATALLNQECPLSWQNKWEGPEDPMQYLRAVVSRALAIQGWVERAERGGLLSEMLDLSELFHPDTFLNALRQETARLMSCSMDSLKFVTTWRGQITEAKLQVKVGGLQLEGCSFDGNRLSESHHDSPSVSSVPPCHMAWIPVSAMGCYSPDECISLPVYSSAERVCVVTNVQLPC-AGDHDTWIQSGAALFLK 4206
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Zebrafish
Match: dnah2 (dynein, axonemal, heavy chain 2 [Source:ZFIN;Acc:ZDB-GENE-130530-910]) HSP 1 Score: 1251.88 bits (3238), Expect = 0.000e+0 Identity = 1146/4583 (25.01%), Postives = 2094/4583 (45.69%), Query Frame = 3
Query: 180 NEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGP-ILLSDTDPK---------IQKLISELENG----LGSIIRKPLSKKSKYQTDETI----------------------VLGIFSIDD---------EIMFWN------DSLSASSHDQNQSRINEL-----------------------------ISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNY--PQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQ-------ILP--------HRERQEFKIEEAFKYFLNILPLAYN--PYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSI--TSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSI------ISQNRLLRKQHFLICEKI-----VNLMGIDLLR--------------QQQKWKDTLNEIRQILFQIENQKHL--PENTLPWKRHL---DHQLYKALEYQYHIGLEALNENL---------PEIRVDLVY------RQGRLQFNPTFEE-------IKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERN----------AAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCL---DLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLI---QNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLR----TVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWS---QFE----EYQTG-LQNLAKE-----DWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNK----DIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQL---SYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTA-------RCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQT-------VKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTV------YNGLSNLKAIKNKAH-----------FSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTL--HCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPK-HPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYS-HYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKD-TIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDN-----LNSYFLDLHDTCPVEFS-------------TSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKI--------------SEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKM-QLWMEKTG-LE-----KFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF--TGTFISDKSDRNITVPKWIDADRTVAISNL--ASAMPELWSVLNIKDDDLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEK---ELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSE-DFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQL-----PSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTD-------SP--VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNV--SAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRD------KIVTKIDIPCQSGQQDKWIQSGVALFL 12986
NE+ LDKF + +LVV ++ + V FI+ S+IT ++ S + ++ I L ++ ++ P + LS T P+ + + +++L + LGS + + +++ +E + VL S+ D EI FW DS+S I E+ ++FL + E + +A E L ++ L+ IW +N +Y + R+ L+ I+NE++R+ +++ ++ K+ L I+ C W ++ + + K + W+ D + + +F R ++ + +Q + LP ++ IE F L +L + P W +F ++ E + + F+ E QLL +FQ L R I + +R+T+ + H +L E + R + P + +I W+K L +++ + + ++ L + ++ + + + F W+Q +++ S + + + +G K GLL +N++ L+ L E+ L ++I V ++ ++ + V + YN I + + + + +K ++ S+ + W+ + FI+ + ++ + L +H CE+I V+L G + R Q + ++ +I +I+ ++ HL PE W ++ D L +A L+ L++ + P RV++V ++ F+P+ ++ I S+ K + F LP+ L + S+IE++ AAG V A +L Q +K +E + ++ + F+ ++ +T ++ + +K + + + ++C+P+K S+ Q+ F LL+ + + + + ++L + LS+ PQ + ++ E+ D ++I SQI + +L V ++ + L +W F+ ++ +M+++ + MK+ ++ ++FQ+ F + P GS+ A+Q++ + + +LE L + N+ F +E + + KD+D Q +W Q+E E++ G L +L E F++ + L F + +E + ++ + I+ +K IIP++ +R L + HW ++ + + + TL I+ A + HAE+I +++ A E++I + + + + + D ++ + E + + DNQ L +K S + + F+ + WE L+ + E ++ + +QR+W+YLE IF + L +E + F V ++ IM ++++ L G+ LS M +L+ QK+L+ YLE KR +FPRFYF+ +DDLLEILGQS NP+ ++ HLKK F I + NK + M S DGE V+ + VL+ VE WL ++ M+ TL D L S AL+ + G +P Q+L + I +T +E +++ + +LKK+ V LN Y+ A + + T I+ LK+ +L+ VH D+I +L C V ++WL QLR Y + C+I+ + F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC EG+D KSMGR++ GL + G+WGCFDEFNR+ VLS V+ QI I + + + R++N+ + IFIT+NP GY GR +LPDNLK +FRP++M PD+ LIAE+ L ++GF N K L +K+ +++L+ + L+ Q HYD+GLRAL ++L+ A K + D ++ ++++ +++ ++KL+ D F +I+D+FP ++ I+Y L A+E +++ + + K++++YE R +IVG +GSGK+ W+ L+ L+ + + ++ +NPKA+ +L G ++ T EW+DGVL+ R + + + WI+ DG +D WIES+NSV+DDN++LT+ +GERI V+ +FE DLS ASPAT+SR GM++ K V SW++K+ + + LL + + K+L + + ++ + + V Y L+ + A F LI + +++E R+ ++ E+ + P NK + YY + K ++ + + KI+ P T D R K ++ TQ P +L+GP G GK+ + Q L ++ TL + S+QT+ +V + + + VY P ++++++L D+N+P +D +G+ + L+ I Y +YD + + + GR+ +S R S L ++++P++ Q+ IY + L+ + PI +L +E+Y + S+F HYLF D+++ LLR +++ L I +E R+F DRLV + G+L + S + V + +G ++ + K+L L+D + G++ S ++LF++ D+V +L RV+++ G++LL G G GR++ + L +++ + ++ + Y ++F+ D+K + GVE + V L D Q ++ +LE IN++L+SGEVP LY +EL+ I +L D A + ++ NY +R+++ LHI+L M F + PA ++ W +W RD++L++ ++ + GSD+ + S F+ +H + +FS T +Y+ + Y ++ +K++E+ + + ++ G+ KI EAK+ VAE + + E ++ +++ EAD+ K + GA K E E++ K EN A+R +D+ L P +++A A+ + D++EI++ PP ++ +++ V+++ G + +W + LG+ +++ FD I+ + + T + F P+ R S+AA L WV+A Y + P + L + + + + + +V + + ++ +++ A +L + ++ + A LV L E RW + + L +S L LLAAA + YM + R E + +WM++ LE F FL+ EW +GL SD S EN +++ +G P ++DP A W+KN + L++++ Q +F +LE +V+FG +++Q V + L+P L P+L L G R +++LGDK I+Y+P+F+ ++ T+ P P+ + + VNF + GL+ QLL + ++ +P+LEE+K +L+ K +L ++E+ +L+ L ATG++L++ L+ +L +K ++ +++ LE S + +D R+A+ P A+ S LFFV++DL I+ MY+FSL +++ LF ++ +S S R +L VY Y CR +F+ +L+F+ HM C + E+ F G + K + W+ I+ L + EL + D WH + + E E+ +P +N + QK+LI+++LR DR+ ++ F + L + + P +++ + +++ + P++ ++SPG DP+ L +L+ +R+ +++GQGQA I L+ + NG W+ L N HL SW+ L+K EL + H DFRLW+++ PH F +LQ+ +KIT E P GVK N+ R Y SE F+ + LFSL +FH++I ERR F+ GW Y F+ +D +L + + I W + L +GG V + +D R+L++YI +YF +V++ F+ L P S+ Y+ I+QL P F N D +SQ + + L LQ V T SRE K+L ++++ +P + T SP VV +++RYN+ L+ + SL+ L K +KG +++ ++ C+ + P +W + + + + R L + + +WAE + L L P FL A+ Q +AR +S+D L + V +N+ K V I L +EG +D C ++ + L+ P+ + +M S P YY +R V +D+ + D WI+ G AL +
Sbjct: 95 NEQALDKFISDSSVRLLVVYHDPFTGLYVDYAMPAQVVEQMSYFIRAPDSMITEESFRSSVQFGSVRGGAIEGLLRMMNGVHTPQVTLSTTWPETSKNNYSAELHRFLTKLTDSRFKLLGSTVLYIPLEALQHRPEEAVKNKNLVQRLEMVVIHWTRQIKAVLSAQSVSDIGDTLGPLEEISFWKSRCADLDSISTQLQKPGVRHIQEILQLYTSTYIPPFCKLAKQIQESSLQAQSNVTFLSLLKEPCEELAQLKPCEIAPKLAHILNLIRVIW----VNSSYFNTRDRITALLRKISNEIIRLCCREISLNRIFQGYAVSSKQILNDCIQCCLAWKELYLHTSQLHHK-HSSQGWSLDQISIFALVDSFMQRCKDLIEICECQQQFARWEDGERVPLPCFAGRLGSEVTQKLLYIEATFDKSLQVLQSVQDILDVRNPSWHEDYSRFRAKLKDLEVMMQNLITSTFEMVNCVEEGVQLLDVFQH---LSGREAIKRTI--DRKTVDVYNLFH-SELVEINLVMCRTSSLIPVQ-MPRYAGQIHWTKALHSRVERSMEVLRRAHFLPHVRSADEMHVIYVKLCQTLDEKVRRIFTDWSQSLSKECHSSLDQPLMIRCKG-------KTGLLDINFNKNLLKLFNEIHYWDRLQFEIPHFVTEVYQRREELHNLRENVLLVVRDYNRIIKDLNADELGLFSERIRFLDKKIQPGLSK------LHWSTKGTPSAFINDCRVHANKVQLMVDEYKAANLATSKH---CEQISELLLVHLDGKTVYRDHEFQEDQQTHQHSQMLRLQNAHQDIIKIMARVYGTFHLDGPEVQQHWTSYMEKIDQMLEEAFRVNIKRSLQELSKAINGDGKISPNPLFRVEVVLTPETARSTAQVDFSPSPQKLAHIVNSISSQLIKTISGFKRLPD----LLTRQQSQRKPIHSIIEQDEEICKIQGAIAAGMVT---NASYL-QTYLKTWDKHRE---IWEIEKDSFIQRYQRLNPTVTSFDADIARYTEVANNVQKEETLLSVQFVLLDCSPLKFSLLQHCNEWQSKFTQLLSLMASS---KLKELHSFLQENAVRLSQPPQTLTDLGESLKLLETLQADLNKIESQIPPIHEQYAILTKYEVAVDPAVLELLEALNAEWVWFQQVVIDSDIMLKKHKDTMKSGLILSSEEFQKKTQTFLQSFSSNGP------FGSSVTPHSALQQVSELRAQLEALKEEEQNICSGLNIFTIEQPASKDILALEKDVDYLQQVWEIARQWEDLWAEWKGGHLASLQTEVMDNTAQTMFKTLHKLSRAFKDKHWEIVDSS---------KSRIEQFKKIIPLITDLRNSALRERHWNQIRQEVQQTFDPSSADFTLEKIV--ALGLDHHAESISDISGAASKELSIEQTLEGIMKTWKEMSLDITPHKDKGHHKLRGTDE---VFQALEDNQVTLSVIKASRFVKAFEKEVDHWERCLSLVLEVIEMILTVQRQWMYLENIFLADDIRKQLVRETAEFDAVTSSWKIIMERLDKDKNALRGTHHPGLLEKLSEMNTKLEEIQKSLDMYLETKRQIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKSLRINKVGTGNKSEASGMFSADGEFVDFTHPVLLEGPVEAWLCDVERTMRWTLKDSLRNCSMALKKM----PGKRGKWVRDWPGQMLITASQIQWTTDVTRALMTSKERADKSALKSLKKKQVSMLNQYSEA---IRGNLTKILR-LKIVALVTVEVHARDVISKLAKGGCCDVNAFDWLCQLRLYWEKDVDDCIIRQTNTHFRYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKSLGMYVIVVNCSEGLDFKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSALSAGLNNFSFEGRQINLIWSCGIFITMNP---GYAGRTELPDNLKSMFRPISMVVPDSTLIAEITLFAEGFNNCKVLAKKVFTLYSLAVQQLSKQDHYDFGLRALTSLLRYAG--------KKRRARPDIVDE--------EILLMSMKDMNIAKLSSIDLPLFNGIIQDLFPAVETPTIDYGKLKEAVEAELRQSGLQVIPFTVTKVIQLYETKNSRHSTMIVGKTGSGKTVTWRTLQNTLSTLHRNGEPGFNLIRECPLNPKAVSLGELYGEYNLSTNEWTDGVLSSLMRMACADEKPDEKWIVFDGPVDTLWIESMNSVMDDNKVLTLINGERISMPEQVSLLFEVEDLSVASPATVSRCGMVYSDYSDLGWKPYVQSWMEKRQKVETDLLWQLFERYIDKTLAFKKTHCKELVAITELNGVASLCRLYQSLATAENGVKPADSENYGRMVELWFIFSLIWSVCASVDEEGRKKIDTFLREI-EGSFP--NKDTIYEYYVDTKNKTWASFEDKLPKGWRYASNAPFYKIMVP---TVDTVRYHYLVKALVS--TQHPVLLTGPVGTGKTSVAQSVLQSLDNITWATLTVNMSSQTSSNNVQEIIESR---VEKRIKGVYVPVGGKKMVVFLDDLNMPAVDNFGSQPPLELLRLWIDYGFWYDRQKQTLKYIKDLFLLGSMGPPGGGRTHISGRLQSRFNLINMTFPTESQIKRIYGTMISQKLQEFEEEVKPIGG------ILTQATLELYHAITSRFLPTPAKIHYLFNLRDISKVFQGLLRAHKDFHDTKQSITRLWI--HECFRVFSDRLVDHADMETFVGVLSEKLASHFDVPFHTICPNKQPPLFGDFLRESQIYEDLLDFKALKVHMENQLEDYNLTPGVVPMS-------LVLFRDAIDHVTRLVRVISQLRGNMLLVGIGGSGRQSLTRLAAYICRFTVFQVEVTKQYRKQEFREDIKKLYRLTGVENKPTVFLFNDTQIVDESFLEDINNILSSGEVPNLYKADELDEIQSALSDSARKDNILETPDAMFNYLIERVRNNLHIVLCMSPVGDPFRNRIRQYPALVNCTTIDWFSEWPRDALLEVAERCLDGLS------------------LGSDDGIQTKVASIFVTVHQSV-AQFSHRMKVELKRHNYVTPTNYLELVSGYKKLLSEKRDELGEQVSKLRNGLFKIDDTRTKVEAMSVELEEAKKKVAEFQKQCEEYLVVIVQQKREADEQQKAV-----GAHSEKIEAEEIKCKAMAEN---AQRD--LDEAL----PALEEAMKALESLNKKDMTEIKSYGRPPALVETVMQAVMILRGC-EPTWAEAKRQLGEGNFIKQLVNFDKDNISDRVLKTIGQYCT--QPDFQPEIIGRVSLAAKSLCMWVRAMEVYGRIFRVVEPKRARLHGAMTQLAEKQAALAEAQGKLREVGEKLDHLKRQYDEKLAQKEELRRKSEDMELKLDRAGKLVSGLAGERVRWKETVDGLEKNMSCLVGDCLLAAAFLSYMGPFLSNHRDELVTDIWMKQVRELEVPCSPGFSFAVFLSKPTAVREWNIQGLPSDAFSTENGVIVTRGNRWPLMVDPQGQALKWIKNMEFKQGLKVIDLQMPDFLRILENAVQFGSPVLLQNVQEELDPSLAPILNKSLTRVGGRFLLKLGDKEIEYSPEFRFYMTTKLSNPHYTPEISSKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIASGKRKLQELEDEILRLLNEATGSLLDDVQLVNTLQTSKVTATEVAEQLEISELTESQIDTAREAYRPCAQRASILFFVLNDLGCIDPMYQFSLDAYINLFILSIESSPRSHKLEERINNLNRHHTYAVYRYTCRGLFECHKLLFSFHM--CAKILEASGKLNMDEYNFFLRGGLVLDTKKQMDNPCSHWLSDSNWDNITELDKLTNFHELMASFEQYPRD-WHHWYTNPEPEKAPLPGEWENSCNELQKMLIVRSLRQDRVSLCVTAFVINNLGSQFVEPPILDMKAVV-ADSTTRTPLIFVLSPGVDPTAALLQLAETSGMGQRFFALSLGQGQAPIATRLIKEGVANGHWVFLANCHLSLSWMCELDKLVDELQVQECHPDFRLWLSSSPHPEFPIAILQTGIKITTEPPRGVKWNMKRLYQRVSETQFLRCSRPLLYRKLLFSLCFFHSVILERRKFLQLGWNIIYSFNDSDFEVSENLLSLYLDEYE-EIPWDALKFLIAGINYGGHVTDDWDRRLLTTYINQYFCPAVIDTP--FFKVSSLVSYYVPRDGSQSSYVDYISQLPALEHPELFGQNPNADIASQITEARTLFHTLLSLQP-QVTSTDTTSAGASRED-------KVLELSADVLQ-KIPAEIDYEGTRKLLKDDLSPLNVVLLQEIQRYNT--LLHTIRLSLLELEKGIKGLVVMSSSLEETFNCIHDARVPPLWEKAYPSLKPLASWTRDLCQRVEQFARWAETARPPVLFW----LSGFTFPTGFLTAVLQSSARQNNVSVDTLSWEFSVTTVEDNNLLFPPKDGVLIQGLFLEGAGWDKK--ASCLVEAEPMQLVCPMPTIHFKPVESRKRLAKNMYSCPCYYYPVRSGSSGRQSFVVAVDLKSGAVPYDHWIKRGTALLM 4502
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Zebrafish
Match: dnah2 (dynein, axonemal, heavy chain 2 [Source:ZFIN;Acc:ZDB-GENE-130530-910]) HSP 1 Score: 1234.55 bits (3193), Expect = 0.000e+0 Identity = 970/3576 (27.13%), Postives = 1729/3576 (48.35%), Query Frame = 3
Query: 2700 LTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLI---QNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLL---RTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWS---QFE----EYQTG-LQNLAKE-----DWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIF----GKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNK----DIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQL---SYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTA-------RCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQT-------VKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTV------YNGLSNLKAIKNKAH-----------FSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTL--HCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPK-HPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYS-HYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKD-TIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDN-----LNSYFLDLHDTCPVEFS-------------TSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKI--------------SEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKM-QLWMEKTG-LE-----KFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF--TGTFISDKSDRNITVPKWIDADRTVAISNL--ASAMPELWSVLNIKDDDLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEK---ELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSE-DFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQL-----PSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTD-------SP--VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNV--SAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRD------KIVTKIDIPCQSGQQDKWIQSGVALFL 12986
+T ++ + +K + + + ++C+P+K S+ Q+ F LL+ + + + + ++L + LS+ PQ + ++ E+ D ++I SQI + +L ++ + L +W F+ ++ +M+++ + MK+ ++ ++FQ+ F + P GS+ A+Q++ + + +LE L + N+ F +E + + KD+D Q +W Q+E E++ G L +L E F++ + L F + +E + ++ + I+ +K IIP++ +R L + HW ++ + + + TL I+ A + HAE+I +++ A E++I + + + + + D ++ + E + + DNQ L +K S + + F+ + WE L+ + E ++ + +QR+W+YLE IF + L +E + F V ++ IM ++++ L G+ LS M +L+ QK+L+ YLE KR +FPRFYF+ +DDLLEILGQS NP+ ++ HLKK F I + NK + M S DGE V+ + VL+ VE WL ++ M+ TL D L S AL+ + G +P Q+L + I +T +E +++ + +LKK+ V LN Y+ A + + T I+ LK+ +L+ VH D+I +L C V ++WL QLR Y + C+I+ + F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC EG+D KSMGR++ GL + G+WGCFDEFNR+ VLS V+ QI I + + + R++N+ + IFIT+NP GY GR +LPDNLK +FRP++M PD+ LIAE+ L ++GF N K L +K+ +++L+ + L+ Q HYD+GLRAL ++L+ A K + D ++ ++++ +++ ++KL+ D F +I+D+FP ++ I+Y L A+E +++ + + K++++YE R +IVG +GSGK+ W+ L+ L+ + + ++ +NPKA+ +L G ++ T EW+DGVL+ R + + + WI+ DG +D WIES+NSV+DDN++LT+ +GERI V+ +FE DLS ASPAT+SR GM++ K V SW++K+ + + LL + + K+L + + ++ + + V Y L+ + A F LI + +++E R+ ++ E+ + P NK + YY + K ++ + + KI+ P T D R K ++ TQ P +L+GP G GK+ + Q L ++ TL + S+QT+ +V + + + VY P ++++++L D+N+P +D +G+ + L+ I Y +YD + + + GR+ +S R S L ++++P++ Q+ IY + L+ + PI +L +E+Y + S+F HYLF D+++ LLR +++ L I +E R+F DRLV + G+L + S + V + +G ++ + K+L L+D + G++ S ++LF++ D+V +L RV+++ G++LL G G GR++ + L +++ + ++ + Y ++F+ D+K + GVE + V L D Q ++ +LE IN++L+SGEVP LY +EL+ I +L D A + ++ NY +R+++ LHI+L M F + PA ++ W +W RD++L++ ++ + GSD+ + S F+ +H + +FS T +Y+ + Y ++ +K++E+ + + ++ G+ KI EAK+ VAE + + E ++ +++ EAD+ K + GA K E E++ K EN A+R +D+ L P +++A A+ + D++EI++ PP ++ +++ V+++ G + +W + LG+ +++ FD I+ + + T + F P+ R S+AA L WV+A Y + P + L + + + + + +V + + ++ +++ A +L + ++ + A LV L E RW + + L +S L LLAAA + YM + R E + +WM++ LE F FL+ EW +GL SD S EN +++ +G P ++DP A W+KN + L++++ Q +F +LE +V+FG +++Q V + L+P L P+L L G R +++LGDK I+Y+P+F+ ++ T+ P P+ + + VNF + GL+ QLL + ++ +P+LEE+K +L+ K +L ++E+ +L+ L ATG++L++ L+ +L +K ++ +++ LE S + +D R+A+ P A+ S LFFV++DL I+ MY+FSL +++ LF ++ +S S R +L VY Y CR +F+ +L+F+ HM C + E+ F G + K + W+ I+ L + EL + D WH + + E E+ +P +N + QK+LI+++LR DR+ ++ F + L + + P +++ + +++ + P++ ++SPG DP+ L +L+ +R+ +++GQGQA I L+ + NG W+ L N HL SW+ L+K EL + H DFRLW+++ PH F +LQ+ +KIT E P GVK N+ R Y SE F+ + LFSL +FH++I ERR F+ GW Y F+ +D +L + + I W + L +GG V + +D R+L++YI +YF +V++ F+ L P S+ Y+ I+QL P F N D +SQ + + L LQ V T SRE K+L ++++ +P + T SP VV +++RYN+ L+ + SL+ L K +KG +++ ++ C+ + P +W + + + + R L + + +WAE + L L P FL A+ Q +AR +S+D L + V +N+ K V I L +EG +D C ++ + L+ P+ + +M S P YY +R V +D+ + D WI+ G AL +
Sbjct: 943 VTSFDADIARYTEVANNVQKEETLLSVQFVLLDCSPLKFSLLQHCNEWQSKFTQLLSLMASS---KLKELHSFLQENAVRLSQPPQTLTDLGESLKLLETLQADLNKIESQIPPIHEQYAILTKYEVAVDPVLELLEALNAEWVWFQQVVIDSDIMLKKHKDTMKSGLILSSEEFQKKTQTFLQSFSSNGP------FGSSVTPHSALQQVSELRAQLEALKEEEQNICSGLNIFTIEQPASKDILALEKDVDYLQQVWEIARQWEDLWAEWKGGHLASLQTEVMDNTAQTMFKTLHKLSRAFKDKHWEIVDSS---------KSRIEQFKKIIPLITDLRNSALRERHWNQIRQEVQQTFDPSSADFTLEKIV--ALGLDHHAESISDISGAASKELSIEQTLEGIMKTWKEMSLDITPHKDKGHHKLRGTDE---VFQALEDNQVTLSVIKASRFVKAFEKEVDHWERCLSLVLEVIEMILTVQRQWMYLENIFLADDIRKQLVRETAEFDAVTSSWKIIMERLDKDKNALRGTHHPGLLEKLSEMNTKLEEIQKSLDMYLETKRQIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKSLRINKVGTGNKSEASGMFSADGEFVDFTHPVLLEGPVEAWLCDVERTMRWTLKDSLRNCSMALKKM----PGKRGKWVRDWPGQMLITASQIQWTTDVTRALMTSKERADKSALKSLKKKQVSMLNQYSEA---IRGNLTKILR-LKIVALVTVEVHARDVISKLAKGGCCDVNAFDWLCQLRLYWEKDVDDCIIRQTNTHFRYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKSLGMYVIVVNCSEGLDFKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSALSAGLNNFSFEGRQINLIWSCGIFITMNP---GYAGRTELPDNLKSMFRPISMVVPDSTLIAEITLFAEGFNNCKVLAKKVFTLYSLAVQQLSKQDHYDFGLRALTSLLRYAG--------KKRRARPDIVDE--------EILLMSMKDMNIAKLSSIDLPLFNGIIQDLFPAVETPTIDYGKLKEAVEAELRQSGLQVIPFTVTKVIQLYETKNSRHSTMIVGKTGSGKTVTWRTLQNTLSTLHRNGEPGFNLIRECPLNPKAVSLGELYGEYNLSTNEWTDGVLSSLMRMACADEKPDEKWIVFDGPVDTLWIESMNSVMDDNKVLTLINGERISMPEQVSLLFEVEDLSVASPATVSRCGMVYSDYSDLGWKPYVQSWMEKRQKVETDLLWQLFERYIDKTLAFKKTHCKELVAITELNGVASLCRLYQSLATAENGVKPADSENYGRMVELWFIFSLIWSVCASVDEEGRKKIDTFLREI-EGSFP--NKDTIYEYYVDTKNKTWASFEDKLPKGWRYASNAPFYKIMVP---TVDTVRYHYLVKALVS--TQHPVLLTGPVGTGKTSVAQSVLQSLDNITWATLTVNMSSQTSSNNVQEIIESR---VEKRIKGVYVPVGGKKMVVFLDDLNMPAVDNFGSQPPLELLRLWIDYGFWYDRQKQTLKYIKDLFLLGSMGPPGGGRTHISGRLQSRFNLINMTFPTESQIKRIYGTMISQKLQEFEEEVKPIGG------ILTQATLELYHAITSRFLPTPAKIHYLFNLRDISKVFQGLLRAHKDFHDTKQSITRLWI--HECFRVFSDRLVDHADMETFVGVLSEKLASHFDVPFHTICPNKQPPLFGDFLRESQIYEDLLDFKALKVHMENQLEDYNLTPGVVPMS-------LVLFRDAIDHVTRLVRVISQLRGNMLLVGIGGSGRQSLTRLAAYICRFTVFQVEVTKQYRKQEFREDIKKLYRLTGVENKPTVFLFNDTQIVDESFLEDINNILSSGEVPNLYKADELDEIQSALSDSARKDNILETPDAMFNYLIERVRNNLHIVLCMSPVGDPFRNRIRQYPALVNCTTIDWFSEWPRDALLEVAERCLDGLS------------------LGSDDGIQTKVASIFVTVHQSV-AQFSHRMKVELKRHNYVTPTNYLELVSGYKKLLSEKRDELGEQVSKLRNGLFKIDDTRTKVEAMSVELEEAKKKVAEFQKQCEEYLVVIVQQKREADEQQKAV-----GAHSEKIEAEEIKCKAMAEN---AQRD--LDEAL----PALEEAMKALESLNKKDMTEIKSYGRPPALVETVMQAVMILRGC-EPTWAEAKRQLGEGNFIKQLVNFDKDNISDRVLKTIGQYCT--QPDFQPEIIGRVSLAAKSLCMWVRAMEVYGRIFRVVEPKRARLHGAMTQLAEKQAALAEAQGKLREVGEKLDHLKRQYDEKLAQKEELRRKSEDMELKLDRAGKLVSGLAGERVRWKETVDGLEKNMSCLVGDCLLAAAFLSYMGPFLSNHRDELVTDIWMKQVRELEVPCSPGFSFAVFLSKPTAVREWNIQGLPSDAFSTENGVIVTRGNRWPLMVDPQGQALKWIKNMEFKQGLKVIDLQMPDFLRILENAVQFGSPVLLQNVQEELDPSLAPILNKSLTRVGGRFLLKLGDKEIEYSPEFRFYMTTKLSNPHYTPEISSKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIASGKRKLQELEDEILRLLNEATGSLLDDVQLVNTLQTSKVTATEVAEQLEISELTESQIDTAREAYRPCAQRASILFFVLNDLGCIDPMYQFSLDAYINLFILSIESSPRSHKLEERINNLNRHHTYAVYRYTCRGLFECHKLLFSFHM--CAKILEASGKLNMDEYNFFLRGGLVLDTKKQMDNPCSHWLSDSNWDNITELDKLTNFHELMASFEQYPRD-WHHWYTNPEPEKAPLPGEWENSCNELQKMLIVRSLRQDRVSLCVTAFVINNLGSQFVEPPILDMKAVV-ADSTTRTPLIFVLSPGVDPTAALLQLAETSGMGQRFFALSLGQGQAPIATRLIKEGVANGHWVFLANCHLSLSWMCELDKLVDELQVQECHPDFRLWLSSSPHPEFPIAILQTGIKITTEPPRGVKWNMKRLYQRVSETQFLRCSRPLLYRKLLFSLCFFHSVILERRKFLQLGWNIIYSFNDSDFEVSENLLSLYLDEYE-EIPWDALKFLIAGINYGGHVTDDWDRRLLTTYINQYFCPAVIDTP--FFKVSSLVSYYVPRDGSQSSYVDYISQLPALEHPELFGQNPNADIASQITEARTLFHTLLSLQP-QVTSTDTTSAGASRED-------KVLELSADVLQ-KIPAEIDYEGTRKLLKDDLSPLNVVLLQEIQRYNT--LLHTIRLSLLELEKGIKGLVVMSSSLEETFNCIHDARVPPLWEKAYPSLKPLASWTRDLCQRVEQFARWAETARPPVLFW----LSGFTFPTGFLTAVLQSSARQNNVSVDTLSWEFSVTTVEDNNLLFPPKDGVLIQGLFLEGAGWDKK--ASCLVEAEPMQLVCPMPTIHFKPVESRKRLAKNMYSCPCYYYPVRSGSSGRQSFVVAVDLKSGAVPYDHWIKRGTALLM 4382
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Zebrafish
Match: si:dkeyp-86b9.1 (si:dkeyp-86b9.1 [Source:ZFIN;Acc:ZDB-GENE-060531-163]) HSP 1 Score: 1163.67 bits (3009), Expect = 0.000e+0 Identity = 868/3140 (27.64%), Postives = 1526/3140 (48.60%), Query Frame = 3
Query: 3576 RNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSL---DGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEEL---LNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEP-QEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWI------AKRNEFTISTSNVGTVYNGLSNLKAIKNK---------AHFSVCLIKG----LGGNLNENSRETFALWVYELT------DEKTPEMNKQ------NVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSD---TQQPFILSGPEGCGKSLMLNHCFQKLK--SVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYD----------SNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKL----LANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDN---TAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQ-----YSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINK---IPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEK-------FDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDG-LEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMS-HCCRPDLFKPQ-EWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNI---KDDDLWHQFAKSSECER-EIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKV-IGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSL-KPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRN----IQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYG------KIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSR--ELNPV-------LNRWKILNQGLNIIKASLPD---------SLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTAR 12638
++A ++ L+ + +++ +P+L ++ + L + HW + + TL ++ A E+ ++ I E+ A E+ I + ++E+E F + Y ++ DI+ + D+ LQS+ S + F WE L+ + E ++ +Q+KW+YLE IF ++ LP+E +F +D+ F+ IM+D ++ + C + L + D L+RCQK+LN+YL+ KR+ FPRF+FI DD+LL ILG S+ P ++ H+ K++ I + F+ + + +L +GEV+EL+ V VE+W+ + EM+ T ++L S+Q + Y ++ + + +T E++ +NE LK + KK++ N + + K+ ++++ VH DI+D + + E+EW QLRFY + ++ A+F Y YEY G +LV TPLTD+ YLTLTQ + M LGG P GPAGTGKTES K L G +V NC EG+D ++G+I GL +CG+WGCFDEFNR++ +VLS +S QIQ I++ + +Q + +++D IFIT+NP GY GR +LP+++K LFRPV + PD I E++L S+GF AK L +K+ ++ L+RE L+ Q HYD+GLRALK+VL A L +G+ + E ++++ALR L K + D F LI D+FP +D + Y + A+E +++E + + Q K++++YE + R ++VGP+G GKS + L + ++G K Y +NPKA+ +L G +D TR+W+DG+L+ R + K ++ + +I+ DGD+D W+E++NSV+DDN+LLT+ +GERI+ + +FE DL ASPAT+SR GM+F+ + W+ + ++ L + + ++D I K+ E + T + T N + L + + C ++ LG +L + R+ F ++ +L+ DEK + + +++F+ Q + V +S + + ++ K + L+ T D R WL ++P +L G G K+ + + L + + T++ S++TT + + + L + T + P +RL++++ D+N+P++D++GT Q I+ L+ ++ G YD +L F+ G + GR+ + RF S+ + +I +P ++ L+ IY++ L+ K + I + K+ L T+I+ SKF HY+F DL++ + + L +T+ T + + E +R+F DRL++ + G + N + + ++ ++ D + +G KS ++ + L + L Q Y+ ++++LF + +++ + R++ G LL G G G+++ + L + ++ + RGY F++DLK+ G+E + +V L D E +LELIN++L SG VP L+ +E E +L L+D A +SG + S+ YF ++ + LHI+L M C++ P S+ W W ++ + + + IP+ + + + + L + L + + T ++Y++FI Y + K I + ++ G+ K+ EA +AEL K EQ +L EK + L++I + A E+K E+ + E+N ++ K + LA P ++ AR A+ D+ SD++EIR+ PP ++ + E +L+I G + +W + + + + + D I V+ L S + + S A + + +V+A + Y I P + +L+RN ++++++ ++ + + K + +E + L+ E + + AA+ L+ L +E +RW K + EL L L+ AA + Y + D R E + + LE+ F + LT E E W EGL DELS++N ++ + P IDP A W+K + L+I + D +F LEL++++G + Q+VD ++PV+ +L ++ RQVV LGDK +DY+P+FKL+L T+ P+ P +N+T T GL+ QLL++ + + +LEE++ L+ E + K L +E+SLL+ELA +TGN+L+N +L+ +L++TK + + + L+ + K + +D RD + P A+ G+ LFFV+++++ +++MY++SL SFL +F +L+ S + R ++I L + VY Y C +F+ +L+F+ +M+ + + PQ E E F +S + + + W+ I L P + L K+ + W + E+ P K LS FQK+L+I+ R DR+ A+S + + K++ P ++ I++ + N PI+ I+SPG++P+ DL +L+ G R +AMGQGQ + LL G WL L+N HL+ WL LEK L + KPH DFRLW+T EP F +LQ SLK+ E P G+K N+ +Y S D + + ++ LA+FHA++QERR + GW Y+F+ +D EILD + K+ I W + L ++GGRV + FD R+L+ Y Y D + + F+ ++P+ K+ Y+ I L N+ F L N + + T+ +D+W+ EL P ++R + ++Q I++ LP+ L + + VV +LER+N KL + SL L + L G ++ E+ ++ L GQ P +W + P+ +I + E+++ + E ++ L L P+++L AL Q T R
Sbjct: 1466 KDARALPVSFFLEGRMKEFRESLPLLLDLKNKALRERHWKSLMERTGTNFEMNPNTFTLENMF--AMELHKYGNVISEIVTSAVKELGIEKGVKEVEETWDSMKFTVHRYFKGTQEHGFILGAVDDILQHLDDDAMNLQSMAGSHFVGPFLATVQQWEKNLSLISETIEVWMLVQQKWMYLESIFIGGDIRSQLPEEAKKFDNIDKTFKKIMTDTVKDPGIKRCCLVPNRLADLQNLSDGLERCQKSLNDYLDSKRNAFPRFFFISDDELLSILG-SSEPTCVQEHMIKMYDNIAALRFDTGMNGEMVANALVSAEGEVMELKQPVPAEGRVEDWMTAVLLEMRRT--NRLITKEAIYFYSHQKSRVDWMLDYQGMVVLATNQVWWTYEVEDVFRRMNEGEKQALK-QYAKKMHQQINDLVKRITEPLKKNDRRKINTVLIIDVHARDIVDSFVRDSITDAREFEWESQLRFYWVKEPDELFVRQCSAQFCYGYEYMGLNGRLVITPLTDRIYLTLTQALSMFLGGAPAGPAGTGKTESTKDLAKALGLLCVVTNCGEGMDYMAVGKILSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALMLHLQRFHFEGQEISLDNRIGIFITMNP---GYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLVAKVLAKKMTVLYKLAREQLSKQSHYDFGLRALKSVLVMAGEL---------KRGSPNLS-------EDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPSFNDAVEAILEENRYIMMPSQVDKVVQMYETMMTRHTTMVVGPTGGGKSVVINTLCQSQTRLGLLTKLYSLNPKAMSVIELYGILDPVTRDWTDGILSNIFRDINKPTDKKERRYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQSHCALLFEVGDLQYASPATVSRCGMVFVDPKNLRYAPYWEKWVNSRAPKEKADLCKLFEKYVPSAIDMIVDGVVDGKQTE-KLKTVILQTDLNMVMQLTVMVDSLLENEDFLFEELECCFLEALYCSLGASLLDKGRQKFDAFIKKLSSLNSVHDEKVLAGPGEIPVYLPTLYDFHFDGTQKKWVPWSSMVSKYIHNPEM----KFIDILVPTVDTTR-----ANWLLEQMVKVKRPVVLVGESGTSKTATIQNFLSNLNTDTTIMMTINFSSRTTSMDLQRTLEAN---VEKRTKDTFGPPMGKRLLVFMDDLNMPRVDEYGTQQPIALLKLLLDRGGMYDRGKELNYKLIKDLGFIAAMG---------KAGGGRNEVDPRFISLFSVFNIPFPEEESLHLIYSSILRGHTKPF--EECIRNICDKLTFCTLELYKTIIKDLPPTPSKF------HYIFNLRDLSR-----VYHGLTLTNPERFCTVTQFVRVWRNECLRVFHDRLINETDKIMVQGHVKNLVEEHFKSDLDSAMRDP--ILFGD---------YRTALKSEPRVYEDILDYDASKALFQEILEEYNENKTKMNLVLFDDALEHLTVIHRIIRMDRGHALLVGVGGSGKQSLTKLAAFTAGYEVFEIVLSRGYSETNFRDDLKTLYLKLGIENKKMVFLFTDAHVAEEGFLELINNMLTSGMVPALFADDEKESVLNQLRDEAMKSGCGPSKESIWQYFVNKSANNLHIVLAMSPVGDTLRTRCRNFPGLVNNTSIDWFSPWPLQALYAVAKSFLGESPMIPKSHSEAVIDHVCMVHSSVGDYSKL--FLQTLRRS---NYVTPKNYLDFINTYSNLLEDKDKYILAQYKRLEGGLDKLKEASGQLAELNVKLDEQKVVLAEKTSACEILLEEICANTAVAEEKKTLAEEKAKEIEEQNKVIVVEKKDAESSLAEALPALEAARIALQDLDKSDVTEIRSFTKPPKQVQTVCECILVIRGYKEINWKTAKGMMSEGNFLRSLMEMDCDSINANQVKHVKAYLRNLNTSLE--EMQGISKAGSGMLRFVEAVMGYCEVARDIKPKREKVARLERNFHQSKRELERIQNELGAIQKELRALGDKYEGAMTEKQLLQEEAEVMERRLVAADKLISGLASENKRWIKDLEELKQRRVRLLGDCLICAAFLSYEGAFSWDFRNEMVYKVWQADVLERGIPLSQPFRIENLLTDEVEISRWGSEGLPPDELSVQNGILTTRSSRFPLCIDPQQQALNWVKKKEEKNNLKISSFNDPDFLKGLELAIKYGFPFLFQDVDEYIDPVIDNVLEKNIKGAEGRQVVVLGDKEVDYDPNFKLYLNTKLANPKFLPAVFGKAMVINYTVTLKGLEDQLLSVIVGFERKELEEQRERLILETSENKRLLKDLEDSLLRELATSTGNMLDNVELIQTLDETKSKANEVFEKLKLAEKTAVDIDTLRDGYRPAAKRGAVLFFVLAEMALVSSMYQYSLASFLEVFDLSLSKSLPNPILPSRLKNIIDTLTQNVYNYGCTGLFERHKLLFSFNMTIKIEQAEGRAPQDELEFFFKGNLSLEKSKRKKLLDWLPDQGWEDIIRLMELFPNEFGTLADDIEKNPEEWKNWYDLDAPEQASFPMKYKENLSPFQKLLLIRCFRLDRVYRAVSDYVTLTMGEKYVQPPVISFEAIFDQSS-PNSPIVFILSPGSEPASDLMKLAKHSGFGVNRLKFLAMGQGQEKVAFQLLDTAVARGQWLMLQNCHLLVKWLRDLEKTLERITKPHPDFRLWLTTEPIKDFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHDKLMNCAHPAFRSLVYVLAFFHAVVQERRKYGKIGWNVPYDFNESDFLVCMEILDTYLTKAQNQGDEIIPWGSLKYLIGEVMYGGRVIDSFDRRILTVYTDEYLGDFIFDTFQPFHFFHNADVDYKIPALGPKQVYVDEIESLPLANTAEVFGLHPNAEIG---------------------YYTQAARDMWTHLIELQPQTGDSGGGISRDEYISQVARDIQSKLPEVFDLDVIRKKLGLEISPTSVVLLQELERFN--KLTVRMSRSLAELQRALAGEVGMSSELDEVARALFNGQIPVIWRKL--APDTLKSLGNWMIHFKRRHEQYSSWVNEGE--PYVMWLSGLHIPESYLTALVQATCR 4499
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Xenopus
Match: DYNC2H1 (dynein, cytoplasmic 2, heavy chain 1 [Source:NCBI gene;Acc:100380107]) HSP 1 Score: 4472.54 bits (11599), Expect = 0.000e+0 Identity = 2301/4304 (53.46%), Postives = 3048/4304 (70.82%), Query Frame = 3
Query: 192 LDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQ-TDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPP--TKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSV---GSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAE-ITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLP-VTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHY----LHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNIT----VPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSG-----NFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
L++F D+ + +L + FSN+L+ D N LVF K P +IT DN+ I+++++ E+PI++LY ++ +Y PILL D DPK+Q ++S+LE GLG+I+RK +S K E + GI + +DE FW + ++ S + R + S Q + + + L+E +E ++D+W+ +P YP+ RMK L++II + L R +Q L + W+ + VKE+L I VC W C+ L + W+++ PH W D + I RL E+ S+R VHE++ LP E + + F+ F+ + P+ YNPYTEP+W+ AV ++ R IEPAE I +LK F E + PQQLL+ FQ++ +L+ RP + L ERETLL +L + K + DF H S P +N + ++ IVW +QL+ K+ + + +L DL GF F K K+ L+++ + QEQFE W +E+ L D + G L ++MEL +G L ++YSDRLV L+REVR LS LG I + AA QKFY +A+ILKQVA FYNTI+ QMI Q+ MML++A+ FE+++K+ +S K + WNNP++L +I+KLQ + + ++NR LRK+H EK+V LM IDLLR QQKWKD L EIR L + PW++H +HQLYKALE+QY IGLEALNENLPEI +DL ++QGRLQF P FEEI+SKY++EMK+FI++PNQFKGL+++ G + IF + ERNA GF+ + KAE LF+RL+A L++FKEW+++G +D++ ++++ D+ D+EKNFKA+K +GKEAE+LP+ IKIDCIT+NC P+K VD LIQ +FD+LL SL+K+I+ + +D ++T +++LS RPQ ++EI EA + HA+ + I ++E N LLR+VAGGG+DT+ L+ KWDKFELMMES Q+M++EQIEVMK + SR + + Q+I KF RW LKP D++++G A + + Q IK+KK+E +EL K L +DC HF +E +F L +EI DI+ WS +EE+ G AKEDW+S+RS+ Y FEEF+ W E+LR E TTM+++LQKEID YK ++P+LK++RGE LSQDHWL++FRLL +P+G TLE L +L A I+ A +KELN +AQGE+TIREA+REL+LWGAGA+F L +Y DS + +I LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK VWE KLA+LDEYLQ LNQIQRKWVYLEPIFG+ ALP+E++RF RVDEDFRSIMSD+ R+NRV L S +G++N L T++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQSTNP VI+SHLKKLF G+ VDF+++ +HIITMKSLDGE V L+N++L+TS+VE WL +L +EMK+TL L ++ + +S+ GI+ ++PSQILCL+E I FT E + E + + EL+ KL+ YT+ S+ + + +LKLK+LILD +HNID++ QL S +W W KQLRFY K D+ C ++MVDAE YTYEYQGNAPKLV+TPLTDKCYLTLTQ + MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQD +KN LL + V +D NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMSRPDN+LIAEVIL S+GFK+AK LGRKLVAIFNL+RELLTPQQHYDWGLRALKTVL+G NLL ++K G +T N E+ ++VQALR+NT+SKLT+AD ++LIKDVFP ID K++EY L++A+++ +E N+ + Q KK LE+YEQLRQRMGVVIVGPSG+GKST+W++LR ALNKIG+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+E Q+I SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLS ASPATISRMGMIFLS E TD++SL+ SWL+ Q + +H L ++ D+F K+L+W+ K+N+F + TS +GTV NGLS+L ++ F V LI GLGGNLN SR FA V+ E P+ K L+ +++ K RL+TYS E L+ + + + + P+I T DIQR LDYFK WL DT+QPFIL GPEGCGK ++L + F +L+S + T+HCSAQT+ HVLQKL Q C++I++NTGRVYRPK+ ERL+LYLKDINLPK DKWGTS L++FLQQV+TY GFYD NLE+VGL+ +QIV SM++ S+GR L+TRFTS+VR+C++ YP +DQL I ++YL+PV+ + + HP W SK+ LA +M++VY Q+++KF+VDDYSHYLFTP LTQW++ L RYDL +S + +LEIV+YE+ R+F+DR+V++ D IL + + +W +V D++ D ++VTWG+ A P G+ LG+L S L+D I +G +QYS R+L+I+ F EV D ++++DRVL+ P GS+LLAG+SGVGRRT + LVSHMH L +PK+ RGYELKQFKNDLK +Q AG+EG+ ++ LLEDHQF+ P +LE+INSLL+SGE+PGLYT EELEP+L LK+ A+E G G + YF + ++ LH++LIMDC+N NF INC+SNPAF+K CSVQW+E WS SM KIP M+I +E Q+ K + S+ NS FL +H++C +T Y+ F+++Y +Y K E+ RQ H+Q G+ K++EAK +V ELK KA EQS LL KQ EAD AL++IT+ MQ A+++K EMEK+ K EE V +A+RK I+DEL ++P V +A++AV +IK LSEIR+LRAPPD+IRDILEGVL +MG DTSWVSM++FL KRG++E+I TFD R IT E RI VEELL + SF+ KNA+RAS AAAPLAAWV ANV+YS+ LEKI PLE EQ+++ NA + TA+AAKLE EL A E I AAE L+ +L+ E +RWN Q+VE+ +LSAL ++ LAAA + Y+ ++PEDQRK ++ WM+ GLE FD+R+FL+TE EQL WK EGL SDELS+ENALVILQ + PFLIDPSS AT WLK H K+ ++E++NQQ VR + I+E GL + GPR VVQ+GDK IDYN DF+LFLATRNP P +PPDA + V+ VNFTTT+AGL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+K+EESLL+ LA + GNIL+NKDL+ SLN+TK SS I +SL ES KLQ+SLD+ER+A+LPLAE S ++F+I DLSKINNMYRFSL +FLRLFQR L + S + +R SLI L+ +VYEYVCRS+FK+D+LMFALH +LF+ EW++FTG I D KSD T VP WI+ +R A++ L +++P L+ L+++D +LW F+KSS CE+E PQ++ KLSLFQ++L++QA+RPDRLQSA+ F C LELK LSP +NL ++ ET++ EPILIIISPGADPSQ+LQEL+ +G + +++VAMGQGQADI + L +C+++G+WLCLKNLHLV SWLPVLEKELNSL+P +FRLW+TAE H F+ ILLQSSLKITYEAPPG+K NL+R+Y++W+ + ISK G RA ALFSLAWFHA+ QERRN+IPQGWTKFYEFS+ADLRA +I+D++ + R+ +W F+HGL ENAI+GGRVDN FD+RVL SY++++F+ SG F LP++ S DY A+I + + + P+FF LP NI RSSQR+ISSQVI QLR L R G+KFD+++WS EL+PVLN WK LNQ N+I + +R SP+ +F+ LE++N+I+LV+ +H SL +LSKV++G+ LLT +VQ L+ LL + P W +WEGPE+P Y+R L+ +A A++ W E +E LLS LDL ELFHPDTFLNALRQ TAR + SMD L+FV W G AK VKI L +EGC FDG ++E DS S+ ++PP + W+ + +YS ++ ISLP+Y RD++VT ID+PC G Q+KWIQSG ALFLK+
Sbjct: 35 LERFLDDGNEFILSGSKAGARVRFSNKLDPGDTKENVLVFFKIRPDVITEDNLYGNILISSMLESPINTLYQAVRQVYAPILLKDEKWSKDFDPKLQSMLSDLEAGLGTILRKSVSSHGKPTFGGEDDLQGILTPNDEFQFWTEVSASKSKSSARERASHFTSLFQSIANYYSTLDNLPLSEVVQLVETTQETVDDVWRQTDYDP-YPEHRMKHLLDIIGSALGRSVQRNLGDMDHWKGPFPTVKENLRAGITVCEQWAAACEHLTGQLWRRFTPHPWKIDT-FSSDSIKKLGGRLAEVLSIRMVHEKLLHFLPSGEDNALRSVKVFEPFIGLNPVHYNPYTEPLWRAAVSQYERIIEPAEQKIAVKLKTYFSEFHDS--PQQLLQAFQKHKELVKRPSLKKVLNLERETLLTRLQDYNKDILSDFESRCHGSPGDSSGPLTGRNLPEVVNNIVWVRQLQMKVEDTVKTADALLSDLSGFPSFRKSAKDLLDQLKVYEQEQFEDWLREINAGLSDPKS-GFSLQPNSQVMELDHSNGTLKIHYSDRLVTLLREVRQLSALGLVIPPKIQQAAKTAQKFYKQAIILKQVAHFYNTIDQQMIQSQRPMMLNSALAFEQIIKNTRTSSGESSQKMHITWNNPKDLQDYIEKLQGVAQQLATENRKLRKKHKDFSEKVVALMNIDLLRHQQKWKDGLLEIRSGLRS--------SDMRPWRQHWNHQLYKALEHQYQIGLEALNENLPEINIDLTFKQGRLQFKPPFEEIRSKYYREMKRFISIPNQFKGLSEA--GEEPIFSVMSERNANGFITVFSKAEDLFRRLAATLDRFKEWVVIGQVDIDVLMNKNLHDVHDWEKNFKALKVRGKEAERLPSSIKIDCITINCNPVKSVVDDLIQTLFDSLLISLKKSIQAHLHEIDIFVTEGMEMLSSRPQTVEEIGEANMKHAQLKLRKPEILPLFKEAEDKNRLLRSVAGGGLDTIGNLRAKWDKFELMMESHQLMVKEQIEVMKEKVKSRVQIYTQEIEKFKARWDQLKPSNDLIETGEEDALVKSAQSIKEKKVEFDELEETKRKLIEDCLHFGLEAPDFFLADEIRIDIEDCTKTWSLYEEFYQGFNEKAKEDWISYRSKCYSFEEFILSWHERLRKMEEHTTMSVKLQKEIDRYKTVVPVLKYVRGEHLSQDHWLDLFRLLGLPKGTTLEKLLFGDLLRVADVIVSKASELKELNSRAQGEITIREALRELDLWGAGAIFTLTDYEDSHSRTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVFVWEQKLAELDEYLQYLNQIQRKWVYLEPIFGRGALPREEARFNRVDEDFRSIMSDIKRDNRVTLLTSRAGIRNSLITILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPAVIQSHLKKLFAGVNSVDFDENFKHIITMKSLDGETVPLKNKILVTSDVEVWLSHLASEMKSTLEKLL---VECITAGKKSHSGIDPLQFPSQILCLAEQIQFTEEVEAAIREQRLHQVDIELMAKLDHYTSIDTSMGDTAGAGILELKLKALILDVIHNIDVVKQLNQAQVYSTEDWAWKKQLRFYLKP-DKKCYVKMVDAEMEYTYEYQGNAPKLVYTPLTDKCYLTLTQALKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRSSCDLLGKEVALDPNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNELIAEVILYSEGFKDAKNLGRKLVAIFNLARELLTPQQHYDWGLRALKTVLRGCGNLLH----QLKKNGKETAIN------ESHMVVQALRLNTMSKLTFADCSRCDALIKDVFPGIDFKDVEYMELSAALQQAFEEANLEIIPSQIKKALELYEQLRQRMGVVIVGPSGAGKSTLWRMLRAALNKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVRESQDINSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSSASPATISRMGMIFLSDENTDLQSLIQSWLRGQPANVRHNLENWIGDYFEKALNWVLKQNDFVVETSLIGTVMNGLSHLHGCTDRGQFIVSLIHGLGGNLNMKSRNEFAKEVFSWARESPPDPRKP--LDTFYDAKTGRLMTYSLEKPHNLTTEDFCNPQTL--PVIRTPDIQRGLDYFKPWLGCDTKQPFILVGPEGCGKGMLLRYAFSQLRSTHIATVHCSAQTSSRHVLQKLTQTCLVISTNTGRVYRPKDCERLVLYLKDINLPKPDKWGTSTLVAFLQQVLTYHGFYDDNLEWVGLENIQIVASMSAGGSIGRHKLTTRFTSVVRICAVDYPERDQLQTICSSYLEPVIHKNLKNHPTWGSLSKIHHLAGSMVQVYEQVRAKFSVDDYSHYLFTPCILTQWIIGLFRYDLTGGSSKQSQDCVLEIVAYEARRLFRDRIVTAKELHVFDNILMSVLQGDWGSDVLDNMTDAFYVTWGALHGAGAVIAPGQPLPPHGRPLGRLNSNDLQDVIKKGAIQYSHMNRELEILFFHEVLDYMSRVDRVLSCPSGSLLLAGRSGVGRRTVTSLVSHMHGAVLFTPKVSRGYELKQFKNDLKQVIQMAGIEGQQVLFLLEDHQFVHPDFLEMINSLLSSGEIPGLYTVEELEPLLSPLKNQASEDGFTGPVLGYFTNSKHNFFLQNLHVVLIMDCTNTNFTINCESNPAFYKKCSVQWMEGWSDKSMKKIPEMVILDPNSKEKMQMDPGYKKVSSD---SEFFNS-FLMIHESCKSYGATPSRYMTFLRVYGSLYSSKIAELTKRQRHLQAGVSKLNEAKALVDELKGKAGEQSLLLKTKQAEADSALQEITTSMQNASDQKAEMEKIQQKIAEEAVKIAERKGKIEDELKEVQPLVNEAKEAVGNIKPESLSEIRSLRAPPDIIRDILEGVLRMMGIFDTSWVSMKSFLAKRGVREDIVTFDVRNITSEIRISVEELLKMKRTSFEEKNARRASAAAAPLAAWVIANVQYSHVLEKIQPLEKEQSKIL----NASTR-------------------------TAEAAKLEAELSKAQEVIQAAELLINQLDGENKRWNSQVVEITEQLSALPKRAQLAAAFITYISAAPEDQRKGSIEQWMKCVGLETFDLRRFLSTESEQLIWKSEGLPSDELSIENALVILQSKICPFLIDPSSQATEWLKTHLKESRMEVINQQ-----------VRL--YIYIKEHIGLSCSFFI---------GPRYVVQIGDKTIDYNEDFRLFLATRNPNPFIPPDAASCVTEVNFTTTRAGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILDNKDLIESLNQTKASSALIQESLSESHKLQLSLDQERNAYLPLAESASKMYFIICDLSKINNMYRFSLAAFLRLFQRILIGKQESKSTDVRIKSLIDALKHMVYEYVCRSLFKADQLMFALHFVRGMHSELFQENEWDVFTGVIIGDMFKKSDSQRTLREQVPSWIEQERAWAVALLKTSLPALYQSLSLEDSNLWSHFSKSSACEQEFPQTVAKKLSLFQQLLVVQAIRPDRLQSAMGLFACKNLELKELSPPPLNLKRL-SKETLAIEPILIIISPGADPSQELQELACAEVGRDCFHEVAMGQGQADIAIQSLRECARDGEWLCLKNLHLVISWLPVLEKELNSLQPKGNFRLWLTAEVHPKFTPILLQSSLKITYEAPPGLKKNLMRTYESWTPEQISKNGQTPRAQALFSLAWFHAVCQERRNYIPQGWTKFYEFSLADLRAAYDIIDRLF-EGKRDFKWDFVHGLLENAIYGGRVDNFFDLRVLRSYLEQFFSSHTTGTSGMSKMAAFPLPFSLPNSCSIMDYRAVIESIPEDDQPAFFGLPANIARSSQRMISSQVISQLRTLSRSVTAGSKFDREVWSNELSPVLNLWKKLNQNSNLIHQKVSPPTERHG--SPISSFIILEQFNAIRLVQSIHQSLAALSKVIRGTSLLTSDVQRLASALLEQKCPLAWQNKWEGPEDPLQYLRGLVARAVAIQNWVEKAENQTLLSDTLDLSELFHPDTFLNALRQETARAMNCSMDNLRFVASWRGKIADAKLQVKISGLQLEGCSFDGNRLSENRHDSPSVSVVPPCYMAWIPQQSLGTYSPEECISLPMYTSAERDRLVTNIDLPC-GGNQNKWIQSGAALFLKN 4245
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Xenopus
Match: DYNC2H1 (dynein, cytoplasmic 2, heavy chain 1 [Source:NCBI gene;Acc:100380107]) HSP 1 Score: 4199.82 bits (10891), Expect = 0.000e+0 Identity = 2205/4293 (51.36%), Postives = 2935/4293 (68.37%), Query Frame = 3
Query: 192 LDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPP--TKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAE-ITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTS-DNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFK----PQEWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSG-----NFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
L++F D+ + +L + FSN+L+ D N LVF K P +IT DN+ I+++++ E+PI++LY ++ +Y PILL D DPK+Q ++S+LE GLG+I+RK +S+ I + +DE FW + ++ S + R + S Q + + + L+E +E ++D+W+ +P YP+ RMK L++II + L R +Q L + W+ + VKE+L I VC W C+ L + W+++ PH W D + I RL E+ S+R VHE++ LP E + + F+ F+ + P+ YNPYTEP+W+ AV ++ R IEPAE I +LK F E + PQQLL+ FQ++ +L+ RP + L ERETLL +L + K + DF H S P +N + ++ IVW +QL+ K+ + + +L DL GF F K K+ L+++ + QEQFE W +E+ L D + ++MEL +G L ++YSDRLV L+REVR LS LG I + AA QKFY +A+ILKQVA FYNTI+ QMI Q+ MML++A+ FE+++K V + K + WNNP++L +I+KLQ + + ++NR LRK+H EK+V LM IDLLR QQKWKD L EIR + +E Q + PW++H +HQLYKALE+QY IGLEALNENLPEI +DL ++QGRLQF P FEEI+SKY++EMK+FI++PNQFKGL+++ G + IF + ERNA GF+ + KAE LF+RL+A L++FKEW+++G +D++ ++++ D+ D+EKNFKA+K +GKEAE+LP+ IKIDCIT+NC P+K VD LIQ +FD+LL SL+K+I+ + +D ++T +++LS RPQ ++EI EA + HA+ + I ++E N LLR+VAGGG+DT+ L+ KWDKFELMMES Q+M++EQIEVMK + SR + + Q+I KF RW LKP D++++G A + + Q IK+KK+E +EL K L +DC HF +E +F L +EI DI+ WS +EE+ G AKEDW+S+RS+ Y FEEF+ W E+LR E TTM+++LQKEID YK ++P+LK++RGE LSQDHWL++FRLL +P+G TLE L +L A I+ A +KELN +AQGE+TIREA+REL+LWGAGA+F L +Y DS + +I LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK VWE KLA+LDEYLQ LNQIQRKWVYLEPIFG+ ALP+E++RF NRV D+ R Q A P I L+ IL N I + G+ VDF+++ +HIITMKSLDGE V L+N++L+TS+VE WL +L +EMK+TL L ++ + +S+ GI+ ++PSQILCL+E I FT E + E + + EL+ KL+ YT+ S+ + + +LKLK+LILD +HNID++ QL S +W W KQLRFY K D+ C ++MVDAE YTYEYQGNAPKLV+TPLTDKCYLTLTQ + MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQD +KN LL + V +D NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMSRPDN+LIAEVIL S+GFK+AK LGRKLVAIFNL+RELLTPQQHYDWGLRALKTVL+G NLL ++K G +T N ++VQALR+NT+SKLT+AD ++LIKDVFP ID K++EY L++A+++ +E N+ + Q KK LE+YEQLRQRMGVVIVGPSG+GKST+W++LR ALNKIG+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+E Q+I SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLS ASPATISRMGMIFLS E TD++SL+ SWL+ Q + +H L ++ D+F K+L+W+ K+N+F + TS +GTV NGLS+L ++ F V LI GLGGNLN SR FA V+ E P+ K L+ +++ K RL+TYS E L+ + + + + P+I T DIQR LDYFK WL DT+QPFIL GPEGCGK ++L + F +L+S + T+HCSAQT+ HVLQKL Q C++I++NTGRVYRPK+ ERL+LYLKDINLPK DKWGTS L++FLQQV+TY GFYD NLE+VGL+ +QIV SM++ S+GR L+TRFTS+VR+C++ YP +DQL I ++YL+PV+ + + HP W SK+ LA +M++VY Q+++KF+VDDYSHYLFTP LTQW++ L RYDL ++VS L ++ S F F I L D ++VTWG+ A P G+ LG+L S L+D I +G +QYS R+L+I+ F EV D ++++DRVL+ P GS+LLAG+SGVGRRT + LVSHMH L +PK+ RGYELKQFKNDLK +Q AG+EG+ ++ LLEDHQF+ P +LE+INSLL+SGE+PGLYT EELEP+L LK+ A+E G G + YF +R+ LH++LIMDC+N NF INC+SNPAF+K CSVQW+E WS SM KIP M+I +E Q+ K + S+ NS FL +H++C +T Y+ F+++Y +Y K E+ RQ H+Q G+ K++EAK +V ELK KA EQS LL KQ EAD AL++IT+ MQ A+++K EMEK+ K EE V +A+RK I+DEL ++P V +A++AV +IK LSEIR+LRAPPD+IRDILEGVL +MG DTSWVSM++FL KRG++E+I TFD R IT E RI VEELL + SF+ K + + A V ++ + + P LK L+ VS V + TA+AAKLE EL A E I AAE L+ +L+ E +RWN Q+VE+ +LSAL ++ LAAA + Y+ ++PEDQRK ++ WM+ GLE FD+R+FL+TE EQL WK EGL SDELS+ENALVILQ + PFLIDPSS AT WLK H K+ ++E++NQQ VR + I+E GL + GPR VVQ+GDK IDYN DF+LFLATRNP P +PPDA + V+ VNFTTT+AGL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+K+EESLL+ LA + GNIL+NKDL+ SLN+TK SS I +SL ES KLQ+SLD+ER+A+LPLAE S ++F+I DLSKINNMYRFSL +FLRLFQR L + S + +R SLI L+ +VYEYVCRS+FK+D+LMFALH +LF+ Q+ L G F S ++ R VP WI+ +R A++ L +++P L+ L+++D +LW F+KSS CE+E PQ++ KLSLFQ++L++QA+RPDRLQSA+ F C LELK LSP +NL ++ ET++ EPILIIISPGADPSQ+LQEL+ +G + +++VAMGQGQADI + L +C+++G+WLCLKNLHLV SWLPVLEKELNSL+P +FRLW+TAE H F+ ILLQSSLKITYEAPPG+K NL+R+Y++W+ + ISK G RA ALFSLAWFHA+ QERRN+IPQGWTKFYEFS+ADLRA +I+D++ + R+ +W F+HGL ENAI+GGRVDN FD+RVL SY++++F+ SG F LP++ S DY A+I + + + P+FF LP NI RSSQR+ISSQVI QLR L R G+KFD+++WS EL+PVLN WK LNQ N+I + +R SP+ +F+ LE++N+I+LV+ +H SL +LSKV++G+ LLT +VQ L+ LL + P W +WEGPE+P Y+R L+ +A A++ W E +E LLS LDL ELFHPDTFLNALRQ TAR + SMD L+FV W G AK VKI L +EGC FDG ++E DS S+ ++PP + W+ ++ +YS ++ ISLP+Y RD++VT ID+PC G Q+KWIQSG ALFLK+
Sbjct: 35 LERFLDDGNEFILSGSKAGARVRFSNKLDPGDTKENVLVFFKIRPDVITEDNLYGNILISSMLESPINTLYQAVRQVYAPILLKDEKWSKDFDPKLQSMLSDLEAGLGTILRKSVSR-------------ILTPNDEFQFWTEVSASKSKSSARERASHFTSLFQSIANYYSTLDNLPLSEVVQLVETTQETVDDVWRQTDYDP-YPEHRMKHLLDIIGSALGRSVQRNLGDMDHWKGPFPTVKENLRAGITVCEQWAAACEHLTGQLWRRFTPHPWKIDT-FSSDSIKKLGGRLAEVLSIRMVHEKLLHFLPSGEDNALRSVKVFEPFIGLNPVHYNPYTEPLWRAAVSQYERIIEPAEQKIAVKLKTYFSEFHDS--PQQLLQAFQKHKELVKRPSLKKVLNLERETLLTRLQDYNKDILSDFESRCHGSPGDSSGPLTGRNLPEVVNNIVWVRQLQMKVEDTVKTADALLSDLSGFPSFRKSAKDLLDQLKVYEQEQFEDWLREINAGLSDPKSGF------SQVMELDHSNGTLKIHYSDRLVTLLREVRQLSALGLVIPPKIQQAAKTAQKFYKQAIILKQVAHFYNTIDQQMIQSQRPMMLNSALAFEQIIK-VRTSFIQKMHITWNNPKDLQDYIEKLQGVAQQLATENRKLRKKHKDFSEKVVALMNIDLLRHQQKWKDGLLEIRSVFSNLEYQGLRSSDMRPWRQHWNHQLYKALEHQYQIGLEALNENLPEINIDLTFKQGRLQFKPPFEEIRSKYYREMKRFISIPNQFKGLSEA--GEEPIFSVMSERNANGFITVFSKAEDLFRRLAATLDRFKEWVVIGQVDIDVLMNKNLHDVHDWEKNFKALKVRGKEAERLPSSIKIDCITINCNPVKSVVDDLIQTLFDSLLISLKKSIQAHLHEIDIFVTEGMEMLSSRPQTVEEIGEANMKHAQLKLRKPEILPLFKEAEDKNRLLRSVAGGGLDTIGNLRAKWDKFELMMESHQLMVKEQIEVMKEKVKSRVQIYTQEIEKFKARWDQLKPSNDLIETGEEDALVKSAQSIKEKKVEFDELEETKRKLIEDCLHFGLEAPDFFLADEIRIDIEDCTKTWSLYEEFYQGFNEKAKEDWISYRSKCYSFEEFILSWHERLRKMEEHTTMSVKLQKEIDRYKTVVPVLKYVRGEHLSQDHWLDLFRLLGLPKGTTLEKLLFGDLLRVADVIVSKASELKELNSRAQGEITIREALRELDLWGAGAIFTLTDYEDSHSRTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVFVWEQKLAELDEYLQYLNQIQRKWVYLEPIFGRGALPREEARF-----------------NRV-----------------DEDFRSQGA------------PHLNMI----LMVILLALENYAFI------CYIGVNSVDFDENFKHIITMKSLDGETVPLKNKILVTSDVEVWLSHLASEMKSTLEKLL---VECITAGKKSHSGIDPLQFPSQILCLAEQIQFTEEVEAAIREQRLHQVDIELMAKLDHYTSIDTSMGDTAGAGILELKLKALILDVIHNIDVVKQLNQAQVYSTEDWAWKKQLRFYLKP-DKKCYVKMVDAEMEYTYEYQGNAPKLVYTPLTDKCYLTLTQALKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRSSCDLLGKEVALDPNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNELIAEVILYSEGFKDAKNLGRKLVAIFNLARELLTPQQHYDWGLRALKTVLRGCGNLLH----QLKKNGKETASN--------HMVVQALRLNTMSKLTFADCSRCDALIKDVFPGIDFKDVEYMELSAALQQAFEEANLEIIPSQIKKALELYEQLRQRMGVVIVGPSGAGKSTLWRMLRAALNKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVRESQDINSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSSASPATISRMGMIFLSDENTDLQSLIQSWLRGQPANVRHNLENWIGDYFEKALNWVLKQNDFVVETSLIGTVMNGLSHLHGCTDRGQFIVSLIHGLGGNLNMKSRNEFAKEVFSWARESPPDPRKP--LDTFYDAKTGRLMTYSLEKPHNLTTEDFCNPQTL--PVIRTPDIQRGLDYFKPWLGCDTKQPFILVGPEGCGKGMLLRYAFSQLRSTHIATVHCSAQTSSRHVLQKLTQTCLVISTNTGRVYRPKDCERLVLYLKDINLPKPDKWGTSTLVAFLQQVLTYHGFYDDNLEWVGLENIQIVASMSAGGSIGRHKLTTRFTSVVRICAVDYPERDQLQTICSSYLEPVIHKNLKNHPTWGSLSKIHHLAGSMVQVYEQVRAKFSVDDYSHYLFTPCILTQWIIGLFRYDLTGGRWYRSSVSCLLLLITSSCTFF-----------------FICI-----------LTDAFYVTWGALHGAGAVIAPGQPLPPHGRPLGRLNSNDLQDVIKKGAIQYSHMNRELEILFFHEVLDYMSRVDRVLSCPSGSLLLAGRSGVGRRTVTSLVSHMHGAVLFTPKVSRGYELKQFKNDLKQVIQMAGIEGQQVLFLLEDHQFVHPDFLEMINSLLSSGEIPGLYTVEELEPLLSPLKNQASEDGFTGPVLGYFTNRVLQNLHVVLIMDCTNTNFTINCESNPAFYKKCSVQWMEGWSDKSMKKIPEMVILDPNSKEKMQMDPGYKKVSSD---SEFFNS-FLMIHESCKSYGATPSRYMTFLRVYGSLYSSKIAELTKRQRHLQAGVSKLNEAKALVDELKGKAGEQSLLLKTKQAEADSALQEITTSMQNASDQKAEMEKIQQKIAEEAVKIAERKGKIEDELKEVQPLVNEAKEAVGNIKPESLSEIRSLRAPPDIIRDILEGVLRMMGIFDTSWVSMKSFLAKRGVREDIVTFDVRNITSEIRISVEELLKMKRTSFEEKVPIILIYRLIFIVLALCATVDFTSLVLCMIPF---SVSLK------------LKFSVSVCSVLVPEKILNASTRTAEAAKLEAELSKAQEVIQAAELLINQLDGENKRWNSQVVEITEQLSALPKRAQLAAAFITYISAAPEDQRKGSIEQWMKCVGLETFDLRRFLSTESEQLIWKSEGLPSDELSIENALVILQSKICPFLIDPSSQATEWLKTHLKESRMEVINQQ-----------VRL--YIYIKEHIGLSCSFFI---------GPRYVVQIGDKTIDYNEDFRLFLATRNPNPFIPPDAASCVTEVNFTTTRAGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILDNKDLIESLNQTKASSALIQESLSESHKLQLSLDQERNAYLPLAESASKMYFIICDLSKINNMYRFSLAAFLRLFQRILIGKQESKSTDVRIKSLIDALKHMVYEYVCRSLFKADQLMFALHFVRGMHSELFQENVSTQQNFLLVGYFDSQRTLRE-QVPSWIEQERAWAVALLKTSLPALYQSLSLEDSNLWSHFSKSSACEQEFPQTVAKKLSLFQQLLVVQAIRPDRLQSAMGLFACKNLELKELSPPPLNLKRL-SKETLAIEPILIIISPGADPSQELQELACAEVGRDCFHEVAMGQGQADIAIQSLRECARDGEWLCLKNLHLVISWLPVLEKELNSLQPKGNFRLWLTAEVHPKFTPILLQSSLKITYEAPPGLKKNLMRTYESWTPEQISKNGQTPRAQALFSLAWFHAVCQERRNYIPQGWTKFYEFSLADLRAAYDIIDRLF-EGKRDFKWDFVHGLLENAIYGGRVDNFFDLRVLRSYLEQFFSSHTTGTSGMSKMAAFPLPFSLPNSCSIMDYRAVIESIPEDDQPAFFGLPANIARSSQRMISSQVISQLRTLSRSVTAGSKFDREVWSNELSPVLNLWKKLNQNSNLIHQKVSPPTERHG--SPISSFIILEQFNAIRLVQSIHQSLAALSKVIRGTSLLTSDVQRLASALLEQKCPLAWQNKWEGPEDPLQYLRGLVARAVAIQNWVEKAENQTLLSDTLDLSELFHPDTFLNALRQETARAMNCSMDNLRFVASWRGKIADAKLQVKISGLQLEGCSFDGNRLSENRHDSPSVSVVPPCYMAWIPQSL-GTYSPEECISLPMYTSAERDRLVTNIDLPC-GGNQNKWIQSGAALFLKN 4149
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Xenopus
Match: DYNC2H1 (dynein, cytoplasmic 2, heavy chain 1 [Source:NCBI gene;Acc:100380107]) HSP 1 Score: 3048.07 bits (7901), Expect = 0.000e+0 Identity = 1579/2867 (55.07%), Postives = 2046/2867 (71.36%), Query Frame = 3
Query: 4434 FQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTS-DNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFK----PQEWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSG-----NFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
+ G+ VDF+++ +HIITMKSLDGE V L+N++L+TS+VE WL +L +EMK+TL L ++ + +S+ GI+ ++PSQILCL+E I FT E + E + + EL+ KL+ YT+ S+ + + +LKLK+LILD +HNID++ QL S +W W KQLRFY K D+ C ++MVDAE YTYEYQGNAPKLV+TPLTDKCYLTLTQ + MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQD +KN LL + V +D NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMSRPDN+LIAEVIL S+GFK+AK LGRKLVAIFNL+RELLTPQQHYDWGLRALKTVL+G NLL ++K G +T N ++VQALR+NT+SKLT+AD ++LIKDVFP ID K++EY L++A+++ +E N+ + Q KK LE+YEQLRQRMGVVIVGPSG+GKST+W++LR ALNKIG+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+E Q+I SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLS ASPATISRMGMIFLS E TD++SL+ SWL+ Q + +H L ++ D+F K+L+W+ K+N+F + TS +GTV NGLS+L ++ F V LI GLGGNLN SR FA V+ E P+ K L+ +++ K RL+TYS E L+ + + + + P+I T DIQR LDYFK WL DT+QPFIL GPEGCGK ++L + F +L+S + T+HCSAQT+ HVLQKL Q C++I++NTGRVYRPK+ ERL+LYLKDINLPK DKWGTS L++FLQQV+TY GFYD NLE+VGL+ +QIV SM++ S+GR L+TRFTS+VR+C++ YP +DQL I ++YL+PV+ + + HP W SK+ LA +M++VY Q+++KF+VDDYSHYLFTP LTQW++ L RYDL ++VS L S + + + L++S F I L D ++VTWG+ A P G+ LG+L S L+D I +G +QYS R+L+I+ F EV D ++++DRVL+ P GS+LLAG+SGVGRRT + LVSHMH L +PK+ RGYELKQFKNDLK +Q AG+EG+ ++ LLEDHQF+ P +LE+INSLL+SGE+PGLYT EELEP+L LK+ A+E G G + YF +R+ LH++LIMDC+N NF INC+SNPAF+K CSVQW+E WS SM KIP M+I +E Q+ K +G + FL +H++C +T Y+ F+++Y +Y K E+ RQ H+Q G+ K++EAK +V ELK KA EQS LL KQ EAD AL++IT+ MQ A+++K EMEK+ K EE V +A+RK I+DEL ++P V +A++AV +IK LSEIR+LRAPPD+IRDILEGVL +MG DTSWVSM++FL KRG++E+I TFD R IT E RI VEELL + SF+ K + + A V ++ + + P LK L+ VS V + TA+AAKLE EL A E I AAE L+ +L+ E +RWN Q+VE+ +LSAL ++ LAAA + Y+ ++PEDQRK ++ WM+ GLE FD+R+FL+TE EQL WK EGL SDELS+ENALVILQ + PFLIDPSS AT WLK H K+ ++E++NQQ VR + I+E GL + GPR VVQ+GDK IDYN DF+LFLATRNP P +PPDA + V+ VNFTTT+AGL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+K+EESLL+ LA + GNIL+NKDL+ SLN+TK SS I +SL ES KLQ+SLD+ER+A+LPLAE S ++F+I DLSKINNMYRFSL +FLRLFQR L + S + +R SLI L+ +VYEYVCRS+FK+D+LMFALH +LF+ Q+ L G F S ++ R VP WI+ +R A++ L +++P L+ L+++D +LW F+KSS CE+E PQ++ KLSLFQ++L++QA+RPDRLQSA+ F C LELK LSP +NL ++ ET++ EPILIIISPGADPSQ+LQEL+ +G + +++VAMGQGQADI + L +C+++G+WLCLKNLHLV SWLPVLEKELNSL+P +FRLW+TAE H F+ ILLQSSLKITYEAPPG+K NL+R+Y++W+ + ISK G RA ALFSLAWFHA+ QERRN+IPQGWTKFYEFS+ADLRA +I+D++ + R+ +W F+HGL ENAI+GGRVDN FD+RVL SY++++F+ SG F LP++ S DY A+I + + + P+FF LP NI RSSQR+ISSQVI QLR L R G+KFD+++WS EL+PVLN WK LNQ N+I + +R SP+ +F+ LE++N+I+LV+ +H SL +LSKV++G+ LLT +VQ L+ LL + P W +WEGPE+P Y+R L+ +A A++ W E +E LLS LDL ELFHPDTFLNALRQ TAR + SMD L+FV W G AK VKI L +EGC FDG ++E DS S+ ++PP + W+ ++ +YS ++ ISLP+Y RD++VT ID+PC G Q+KWIQSG ALFLK+
Sbjct: 1368 YIGVNSVDFDENFKHIITMKSLDGETVPLKNKILVTSDVEVWLSHLASEMKSTLEKLL---VECITAGKKSHSGIDPLQFPSQILCLAEQIQFTEEVEAAIREQRLHQVDIELMAKLDHYTSIDTSMGDTAGAGILELKLKALILDVIHNIDVVKQLNQAQVYSTEDWAWKKQLRFYLKP-DKKCYVKMVDAEMEYTYEYQGNAPKLVYTPLTDKCYLTLTQALKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRSSCDLLGKEVALDPNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNELIAEVILYSEGFKDAKNLGRKLVAIFNLARELLTPQQHYDWGLRALKTVLRGCGNLLH----QLKKNGKETASN--------HMVVQALRLNTMSKLTFADCSRCDALIKDVFPGIDFKDVEYMELSAALQQAFEEANLEIIPSQIKKALELYEQLRQRMGVVIVGPSGAGKSTLWRMLRAALNKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVRESQDINSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSSASPATISRMGMIFLSDENTDLQSLIQSWLRGQPANVRHNLENWIGDYFEKALNWVLKQNDFVVETSLIGTVMNGLSHLHGCTDRGQFIVSLIHGLGGNLNMKSRNEFAKEVFSWARESPPDPRKP--LDTFYDAKTGRLMTYSLEKPHNLTTEDFCNPQTL--PVIRTPDIQRGLDYFKPWLGCDTKQPFILVGPEGCGKGMLLRYAFSQLRSTHIATVHCSAQTSSRHVLQKLTQTCLVISTNTGRVYRPKDCERLVLYLKDINLPKPDKWGTSTLVAFLQQVLTYHGFYDDNLEWVGLENIQIVASMSAGGSIGRHKLTTRFTSVVRICAVDYPERDQLQTICSSYLEPVIHKNLKNHPTWGSLSKIHHLAGSMVQVYEQVRAKFSVDDYSHYLFTPCILTQWIIGLFRYDLTGGRWYRSSVSCLVCYSIQYINLL--LLITSSCT-----FFFICI-----------LTDAFYVTWGALHGAGAVIAPGQPLPPHGRPLGRLNSNDLQDVIKKGAIQYSHMNRELEILFFHEVLDYMSRVDRVLSCPSGSLLLAGRSGVGRRTVTSLVSHMHGAVLFTPKVSRGYELKQFKNDLKQVIQMAGIEGQQVLFLLEDHQFVHPDFLEMINSLLSSGEIPGLYTVEELEPLLSPLKNQASEDGFTGPVLGYFTNRVLQNLHVVLIMDCTNTNFTINCESNPAFYKKCSVQWMEGWSDKSMKKIPEMVILDPNSKEKMQMDPGYKKVS---SGDSEFFNSFLMIHESCKSYGATPSRYMTFLRVYGSLYSSKIAELTKRQRHLQAGVSKLNEAKALVDELKGKAGEQSLLLKTKQAEADSALQEITTSMQNASDQKAEMEKIQQKIAEEAVKIAERKGKIEDELKEVQPLVNEAKEAVGNIKPESLSEIRSLRAPPDIIRDILEGVLRMMGIFDTSWVSMKSFLAKRGVREDIVTFDVRNITSEIRISVEELLKMKRTSFEEKVPIILIYRLIFIVLALCATVDFTSLVLCMIPF---SVSLK------------LKFSVSVCSVLVPEKILNASTRTAEAAKLEAELSKAQEVIQAAELLINQLDGENKRWNSQVVEITEQLSALPKRAQLAAAFITYISAAPEDQRKGSIEQWMKCVGLETFDLRRFLSTESEQLIWKSEGLPSDELSIENALVILQSKICPFLIDPSSQATEWLKTHLKESRMEVINQQ-----------VRL--YIYIKEHIGLSCSFFI---------GPRYVVQIGDKTIDYNEDFRLFLATRNPNPFIPPDAASCVTEVNFTTTRAGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILDNKDLIESLNQTKASSALIQESLSESHKLQLSLDQERNAYLPLAESASKMYFIICDLSKINNMYRFSLAAFLRLFQRILIGKQESKSTDVRIKSLIDALKHMVYEYVCRSLFKADQLMFALHFVRGMHSELFQENVSTQQNFLLVGYFDSQRTLRE-QVPSWIEQERAWAVALLKTSLPALYQSLSLEDSNLWSHFSKSSACEQEFPQTVAKKLSLFQQLLVVQAIRPDRLQSAMGLFACKNLELKELSPPPLNLKRL-SKETLAIEPILIIISPGADPSQELQELACAEVGRDCFHEVAMGQGQADIAIQSLRECARDGEWLCLKNLHLVISWLPVLEKELNSLQPKGNFRLWLTAEVHPKFTPILLQSSLKITYEAPPGLKKNLMRTYESWTPEQISKNGQTPRAQALFSLAWFHAVCQERRNYIPQGWTKFYEFSLADLRAAYDIIDRLF-EGKRDFKWDFVHGLLENAIYGGRVDNFFDLRVLRSYLEQFFSSHTTGTSGMSKMAAFPLPFSLPNSCSIMDYRAVIESIPEDDQPAFFGLPANIARSSQRMISSQVISQLRTLSRSVTAGSKFDREVWSNELSPVLNLWKKLNQNSNLIHQKVSPPTERHG--SPISSFIILEQFNAIRLVQSIHQSLAALSKVIRGTSLLTSDVQRLASALLEQKCPLAWQNKWEGPEDPLQYLRGLVARAVAIQNWVEKAENQTLLSDTLDLSELFHPDTFLNALRQETARAMNCSMDNLRFVASWRGKIADAKLQVKISGLQLEGCSFDGNRLSENRHDSPSVSVVPPCYMAWIPQSL-GTYSPEECISLPMYTSAERDRLVTNIDLPC-GGNQNKWIQSGAALFLKN 4149 HSP 2 Score: 1196.03 bits (3093), Expect = 0.000e+0 Identity = 618/1348 (45.85%), Postives = 884/1348 (65.58%), Query Frame = 3
Query: 192 LDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPP--TKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAE-ITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIM 4199
L++F D+ + +L + FSN+L+ D N LVF K P +IT DN+ I+++++ E+PI++LY ++ +Y PILL D DPK+Q ++S+LE GLG+I+RK +S+ I + +DE FW + ++ S + R + S Q + + + L+E +E ++D+W+ +P YP+ RMK L++II + L R +Q L + W+ + VKE+L I VC W C+ L + W+++ PH W D + I RL E+ S+R VHE++ LP E + + F+ F+ + P+ YNPYTEP+W+ AV ++ R IEPAE I +LK F E + PQQLL+ FQ++ +L+ RP + L ERETLL +L + K + DF H S P +N + ++ IVW +QL+ K+ + + +L DL GF F K K+ L+++ + QEQFE W +E+ L D + ++MEL +G L ++YSDRLV L+REVR LS LG I + AA QKFY +A+ILKQVA FYNTI+ QMI Q+ MML++A+ FE+++K V + K + WNNP++L +I+KLQ + + ++NR LRK+H EK+V LM IDLLR QQKWKD L EIR + +E Q + PW++H +HQLYKALE+QY IGLEALNENLPEI +DL ++QGRLQF P FEEI+SKY++EMK+FI++PNQFKGL+++ G + IF + ERNA GF+ + KAE LF+RL+A L++FKEW+++G +D++ ++++ D+ D+EKNFKA+K +GKEAE+LP+ IKIDCIT+NC P+K VD LIQ +FD+LL SL+K+I+ + +D ++T +++LS RPQ ++EI EA + HA+ + I ++E N LLR+VAGGG+DT+ L+ KWDKFELMMES Q+M++EQIEVMK + SR + + Q+I KF RW LKP D++++G A + + Q IK+KK+E +EL K L +DC HF +E +F L +EI DI+ WS +EE+ G AKEDW+S+RS+ Y FEEF+ W E+LR E TTM+++LQKEID YK ++P+LK++RGE LSQDHWL++FRLL +P+G TLE L +L A I+ A +KELN +AQGE+TIREA+REL+LWGAGA+F L +Y DS + +I LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK VWE KLA+LDEYLQ LNQIQRKWVYLEPIFG+ ALP+E++RF RVDEDFR ++
Sbjct: 35 LERFLDDGNEFILSGSKAGARVRFSNKLDPGDTKENVLVFFKIRPDVITEDNLYGNILISSMLESPINTLYQAVRQVYAPILLKDEKWSKDFDPKLQSMLSDLEAGLGTILRKSVSR-------------ILTPNDEFQFWTEVSASKSKSSARERASHFTSLFQSIANYYSTLDNLPLSEVVQLVETTQETVDDVWRQTDYDP-YPEHRMKHLLDIIGSALGRSVQRNLGDMDHWKGPFPTVKENLRAGITVCEQWAAACEHLTGQLWRRFTPHPWKIDT-FSSDSIKKLGGRLAEVLSIRMVHEKLLHFLPSGEDNALRSVKVFEPFIGLNPVHYNPYTEPLWRAAVSQYERIIEPAEQKIAVKLKTYFSEFHDS--PQQLLQAFQKHKELVKRPSLKKVLNLERETLLTRLQDYNKDILSDFESRCHGSPGDSSGPLTGRNLPEVVNNIVWVRQLQMKVEDTVKTADALLSDLSGFPSFRKSAKDLLDQLKVYEQEQFEDWLREINAGLSDPKSGF------SQVMELDHSNGTLKIHYSDRLVTLLREVRQLSALGLVIPPKIQQAAKTAQKFYKQAIILKQVAHFYNTIDQQMIQSQRPMMLNSALAFEQIIK-VRTSFIQKMHITWNNPKDLQDYIEKLQGVAQQLATENRKLRKKHKDFSEKVVALMNIDLLRHQQKWKDGLLEIRSVFSNLEYQGLRSSDMRPWRQHWNHQLYKALEHQYQIGLEALNENLPEINIDLTFKQGRLQFKPPFEEIRSKYYREMKRFISIPNQFKGLSEA--GEEPIFSVMSERNANGFITVFSKAEDLFRRLAATLDRFKEWVVIGQVDIDVLMNKNLHDVHDWEKNFKALKVRGKEAERLPSSIKIDCITINCNPVKSVVDDLIQTLFDSLLISLKKSIQAHLHEIDIFVTEGMEMLSSRPQTVEEIGEANMKHAQLKLRKPEILPLFKEAEDKNRLLRSVAGGGLDTIGNLRAKWDKFELMMESHQLMVKEQIEVMKEKVKSRVQIYTQEIEKFKARWDQLKPSNDLIETGEEDALVKSAQSIKEKKVEFDELEETKRKLIEDCLHFGLEAPDFFLADEIRIDIEDCTKTWSLYEEFYQGFNEKAKEDWISYRSKCYSFEEFILSWHERLRKMEEHTTMSVKLQKEIDRYKTVVPVLKYVRGEHLSQDHWLDLFRLLGLPKGTTLEKLLFGDLLRVADVIVSKASELKELNSRAQGEITIREALRELDLWGAGAIFTLTDYEDSHSRTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVFVWEQKLAELDEYLQYLNQIQRKWVYLEPIFGRGALPREEARFNRVDEDFRMVI 1356
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Xenopus
Match: DNAH2 (dynein, axonemal, heavy chain 2 [Source:NCBI gene;Acc:100170584]) HSP 1 Score: 1251.5 bits (3237), Expect = 0.000e+0 Identity = 941/3399 (27.68%), Postives = 1667/3399 (49.04%), Query Frame = 3
Query: 2778 IDCITVNCAPIKMSVDTLI---QNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLR---TVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKL---------RNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNK----DIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLR-MSNQSNYGINADKYPSQILCLSEMIHFTA-------RCEELLNENNIITLKKELVKKLNIYTNA-KMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLR---LALNKIG----QTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQ--VTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVK----LLANTMIEVYSQLKSKFTVDDYS-HYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRE--CRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFS-------------TSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRC-KDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKT------GLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF-TGTFISDKSDR-NITVPKWI---DADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLK---PHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTG-SGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRD-----YLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQ---RFSVHG---TKFDK--DIWS--RELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF 12671
I + ++C+ +K ++ QN F LL+ + + + YL ++ + + PQ ++E+A++ + + ++++SQI + +L V + T++ L W F+ + + M+++ E KT+++ ++F++ + + P S+ C A+++I + +E L + + F++E L + KD+D QL+W +E++ + +L+ ++ L E + +L +N EI + ++ ID +K +P++ +R L + HW ++ + + P T E TL I++ + +H E I E++ A E+ I + + + + ++ Y D ++ + + D+ + DNQ L ++K SP+ + F+ WE L+ + E ++ + +QR+W+YLE IF + LP+E + F ++ ++ IM + ++N L G+ L M L+ QK+L+ YLE KR +FPRFYFI +DDLLEILGQS NP ++ HLKK F I + K M S +GE V+ + VL+ VE WL ++ M+ TL + L L+ MS++ + + ++ Q+L S I +TA +E + + +KK+ V LN Y++A + +L+ + LKL +L+ VH D+ID++L C V +EWL QLR Y C+I+ + +F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC EG+D KSMGR++ GL + G+WGCFDEFNR+ VLS V+ QI I + + R +N+ + IFIT+NP GY GR +LPDNLK +FRP++M PD+ LIAE+IL +GF N K L +K+ +++L+ + L+ Q HYD+GLRAL ++L+ + K + Q N + E V ++ A++ ++KLT D F +++D+FP I+ ++Y L IE+ +K + K++++YE R ++VG + SGK+TIW+ L+ ALNK G V+ + +NPKA+ +L G D+ T EW+DG+L+ R + + + WI+ DG +D WIES+NSV+DDN++LT+ +GERI V+ +FE DL+ ASPAT+SR GM++ + + V SWL+K + + +YL + ++ F CL+ + +++E R ++ E+ + P +K V YY + K V++ + + I KI+ P + T Q F + Q P +L GP G GK+ + Q L S + V T++ SAQTT +V + + T VY P +RLI +L D+N+P D +G+ + L+ I Y +YD + + + + GR+++S+R S L ++++PS+ Q+ I+ + L+ + +VK L+ +E+Y+ + +F HYLF D+++ +LR + +T S+ + +E R+F DRLV S +D F I SE ++ N + S++P G + LK ++R L + S+ ++LF + +V ++ RV+ +P G++LL G G GR++ + L S++ + K+ ++ RGY ++F+ D+K + AGV+ V LL D Q + +LE +N++L+SGEVP LY +E E I +L + A E SL N+ +R+++ LHI+L M F + PA ++ W +W ++++L++ + EG QL + G + F+ +H + EFS T Y+ + Y + +K+ E+ + ++ G+ KI E +E V ++ + A + E Q + ++ L I + A E++ + + K E + +L P +++A A+ + D++EI++ PP ++ +++ V+++ G + +W + LG+ +++ FD I+ R+ ++++ C F P + S+AA L WV+A Y + P N L + + + + + +V + + + +++ A L E + + A LV L E RW + + L+ +L L LLA+A + YM R+ + +W+++ F + FL++ EW +GL SD S +N +++ +G P ++DP AT W+K+ + L++++ Q ++F LE +V+FG +++Q V + L+P L P+L + G + ++LGDK I YNP+F+ ++ T+ P P+ + + VNF + GL+ QLL ++ +P+LEE+K +L+ K +L ++E+ +L+ L ATG++L++ LL +L +K ++ +S+ LE S + + +D R+A+ P A+ S LFFV++DL +I+ MY+FSL S+ LF +++ S+ S + R +L VY Y CR++F+ +L+F+ M C + E+ F G + D+ ++ + W+ + D + LA+ + S D WHQ+ S E E +P +N S Q++LI+++LR DR+ ++ F + L K P +++ + E +++ P++ ++SPG DP+ L +L+ + ++ ++ +++GQGQA I ++ + ++G W+ L N HL SW+P L+K + L+ PH +FRLW+++ PH F +LQ+S+K+T E P G++ N+ R Y +E S S + LFSL +FH+++ ERR F+ GW Y F+ +D +L + + W+ + L +GG V + +D R+LS+YI YF++ + + FY L + RD Y I+ L + P F N D +SQ + + L LQ S G T+ +K D+ S RE P +I +G + + P+ L VV +++RYN+ L+ + +SL L + ++G +++ E++ + C+ + P +W + + + + R L+L+ + +WA+ + L L P FL A+ Q AR +S+D L +
Sbjct: 974 IQFVLLDCSHLKFALVQHCNEWQNKFTGLLSHM---ASAKLMELHGYLRDNADRVLQPPQTLEELAQSLQLYETLQSELAKVQSQIPPIHEQFAILEKYEVVVDEVLQTLASLNGAWISFQQSLIDSESMLKKSKEKFKTSLIHTAEEFKKKTHSLLEEFTAKGPFL------SSLGCEPALEQISMTREMMETLKAEENTIHLGLSMFKIEQPSSKDLRALEKDLDSLQLVWEATQEWEQRWEEWKSGSFLTLQTD--LMESTAQGLYRRLSKLSRELKEKNWEIVETS---RQRIDQFKRTMPLIADLRNPALRERHWSQVKQEVQGPFDETAEDFTLEKIVELG--LDQHVEKISEISTSATKELFIEQGLENISKTWEATLLDIMPYKDKGHHRL---RGTDDVFQALEDNQVALSTMKASPFVKAFEQDVDRWERCLSHILEVIEMILTVQRQWLYLENIFTGEDIRKQLPQESAEFDDINVSWKVIMGRLTKDNNALRGTHHPGLLEKLGEMNGVLEGIQKSLDMYLETKRHIFPRFYFISNDDLLEILGQSRNPDAVQPHLKKCFDNIKSLKIQKAGIGSKYEAAGMFSAEGEYVDFTHPVLLEGPVEAWLCDIERTMRWTLKELLRNCRLALKKMSSKRDKWVK--EWAGQMLITSSQIQWTADVTKSLMAAKERGEKKILKIMKKKQVSMLNKYSDAIRGNLTKNLR-----LKLVALVTVEVHARDVIDKMLKSGCMDVASFEWLSQLRLYWDKDVDDCLIRQTNTQFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGMYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILTALSANLTRFVFEGREINLVWSCGIFITMNP---GYAGRTELPDNLKSMFRPISMVVPDSTLIAEIILFGEGFNNCKVLAKKVYTLYSLAVQQLSKQDHYDFGLRALTSLLRYSGR-------KRRLQPNLSDEEV---------LIMAMKDMNVAKLTSVDLPLFSGIMQDLFPGIETPTVDYGKLREQIEQELKLSGLQVTPFTVSKVIQLYETKTSRHSTMLVGRTCSGKTTIWRCLQGALSALNKAGDGNYNQVRDFPLNPKALSLGELYGEYDLTTNEWTDGILSSLMRTACADDRPEEKWILFDGPVDTLWIESMNSVMDDNKVLTLINGERIAMPEQVSLLFEVSDLAVASPATVSRCGMVYTDHTSLGWRPYVQSWLEKHPKVNPSDPESYL----------------------RMAELW--------------FLFCLVWSVCASVDEEGRRKIDNYLREM-EGSFP--SKDTVYEYYVDPKTKNWVSFEDKLPKGWRIPTNAPFYKIVVPTVDTVRYQ-----FIVNALVSHQSPVLLVGPVGTGKTSIAQSVLQSLDSSKWAVLTVNMSAQTTTNNVQDIIESR---VEKRTKGVYVPSGGKRLITFLDDLNMPAKDTFGSQPPLELLRLWIDYGFWYDRQNQSIKYIKDMFIMAAMGPPGGGRTAISSRLQSRFNLINMTFPSESQIRRIFGTMMSQKLQDF---------DEEVKPVGDLITQATVELYNAITQRFLPTPAKIHYLFNLRDISKVFQGMLRAQRDL--HDTKQSITRLWVHECFRVFSDRLVDS-----SDADAFVAILSE---KLGSLFNLTYHNLCPSKQPPVFGDFLREPPVYEDITDFQALKTFMNRQLQEQSQRPGAGAKSLVLFTDAIQHVTRIVRVIGQPRGNMLLVGIGGSGRQSLARLASYICDYKVFQLEVTRGYRKQEFREDIKRLYRLAGVDDRPSVFLLTDTQITDESFLEDVNNILSSGEVPNLYKADEFEEIKSALSEKAREQNIPDTPESLFNFLIERVRNNLHIVLCMSPVGDPFRNRIRQYPALVNCTTIDWFSEWPQEALLEVAERYL------EGVQLGAIDG-----IQG--KVARIFVTMHRSV-AEFSHRMKLELRRHNYITPTSYLEVVSRYKSLLAEKRKELGDKATKLRNGLFKIDETREKVEKMSEQLAVARSKVAEFQKQCEEYLVIIVQQRREADEQQKTVAAHSEKIAAEEIKCKALAENAQKDLEEALPALEEAMRALESLNKKDMTEIKSYGRPPALVETVMQAVMILRGN-EPTWAEAKRQLGESNFIKQLIHFDKDNIS--DRV-LKKIGQYCILPDFQPDIIGKVSLAARSLCMWVRAMEVYGRLFRVVEPKRARMNAAMNQLAEKQASLAEAQNKLREVAERLEQLKTQYDEKLAQKEALRAEAELMELKLQRAGTLVTGLAGEKSRWEETVKGLDEDLGFLVGDCLLASAYLSYMGPFLSSYREGILSIWIKEVREMLVPCSAVFSLTNFLSSPTMVREWNLQGLPSDSFSSDNGVIVTRGNRWPLMVDPQGQATKWIKSMESAKGLKVIDLQMTDFMRTLEQAVQFGFPVLLQNVQEELDPSLAPILNKSVTKVGGQLQIRLGDKDIVYNPEFRFYITTKLSNPHYTPEISSQATIVNFAVKEQGLEAQLLGSVVRKERPELEEQKQSLVLNIAAGKRKLQELEDEILRLLNEATGSLLDDVQLLNTLQTSKVTATEVSEQLESSEETEEKIDTAREAYRPCAQRASLLFFVLNDLGRIDPMYQFSLDSYTDLFHLSIDKSKRSANVEERIANLNDWHTYAVYRYTCRALFERHKLLFSFQM--CAKILEVAGKLNMDEYNFFLRGGVVLDREEQMDNPCSAWLSDTNWDNITELDKLANFHGIMNSFEQYPRD--WHQWYTSPEPESACLPGEWENSCSEIQRMLIVRSLRQDRVAFCVTSFIINNLGSKFTEPPVLDMRAVVE-DSLPRSPLVFVLSPGVDPTGALLQLAEQCGMAQNFHALSLGQGQAPIATRMIKEGVKDGHWVFLANCHLSLSWMPQLDKLVEQLQIEDPHPNFRLWLSSSPHPDFPISILQASIKMTTEPPKGLRANMTRLYQLITEQQFSHCAKSSSYRRLLFSLCFFHSVLLERRKFLQLGWNIVYGFNDSDFEVSENLLSLYLDEYEET-PWEALKYLIAGVNYGGHVTDDWDRRLLSTYINDYFSEPAL--TNQFYRLSSLDTYYIPRDGPLASYKEFISLLPAADHPEAFGQHPNADIASQITEARTLFDTLLSLQPQITPSAQGGGQTREEKVLDLLSDVREKIPP----EIDYEGTCKVLSGDPNPLN-------VVLLQEIQRYNA--LLDTIRTSLNDLERGIQGLVVMSAELEEIFTCIYDARVPPLWEKAYPSLKPLAAWTRDLVLRVELFSRWAKTAHPPVLFW----LSAFTFPTGFLTAVLQSAARQNNVSVDSLSW 4218
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Xenopus
Match: DNAH10 (dynein axonemal heavy chain 10 [Source:NCBI gene;Acc:100492440]) HSP 1 Score: 1208.74 bits (3126), Expect = 0.000e+0 Identity = 920/3284 (28.01%), Postives = 1605/3284 (48.87%), Query Frame = 3
Query: 3609 LQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRE-LELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDF----NKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADK--------YPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADS--TFIVHDL------KLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQS-WIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLK-KQDEHDQHLLSTYLDDFFYKSLDWI---------AKRNEFTISTSNVGTVYNGLSNLKAIKNK---------AHFSVCLIKGLGGNLNENSRETFALWVYELT------DEKT----PEMNKQ--NVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDT---QQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDS----------NLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTM----IEVYSQL-------KSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLND-VWFVTWGS--REXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCP------------VEFSTSRHYINFIKMYIRIYLKKKNEIETRQ-NHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEK-------FDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDG-LEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMS-HCCRPDLFKPQ-EWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNI---KDDDLWHQFAKSSECER-EIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKV-IGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSL-KPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKS----NRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSG--NFYGK----IQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSR--ELNPV-------LNRWKILNQGLNIIKASLP-----DSLKRS----STDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPF-DYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIG------NLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDK-----IVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
L+ ++ +K+ IP+L ++ E L HW E+ + E TL ++ A E+ ++A+AI ++ A E++I + ++E L+ W F + YI + S++ +I+ + DN LQS+ S + F + WE L+ + E ++ +QRKW+YLE IF ++ LP E +F +D F+ IMS+ ++ + C S + L + + L+RCQK+LN+YL+ KR+ FPRF+FI DD+LL ILG S++P ++ H+ K++ I + F N +++ M S +GEV+ R V VE+W+ + EM+ T + ++ ++ + DK Y ++ + +T E++ + +KK + L Y KM D T I L K ++++ VH DI+D + + E+EW QLRFY + ++ F Y YEY G +LV TPLTD+ YLTLTQ + M LGG P GPAGTGKTE+ K L G +V NC EG+D K++G+IF GL +CG+WGCFDEFNR++ +VLS +S QIQ I++ + + ++ + + +D IFIT+NP GY GR +LP+++K LFRPV + PD I E++L S+GF AK L +K+ ++ L+RE L+ Q HYD+GLRALK+VL A L K D E+V ++++ALR L K + D F LI D+FP +D + Y + A+EE ++E N + L Q K++++YE + R ++VGP+G GKS + L LA K+G K Y +NPKA+ +L G +D TR+W+DGVL+ R++ K ++ + +I+ DGD+D W+E++NSV+DDN+LLT+ +GERI+ P+ +FE DL ASPAT+SR GM+F+ + W+ +Q + +Q +LS + + ++ I ++ + + +++ V + L A+ K +F + LG L E R F ++ L DE E+ Q + +++F+ ++ + + +S + + ++K + L+ T D R WL ++P +L G G K+ + + L + + +++ S++TT + + + L + T Y P +RL++++ D+N+PK+D++GT Q I+ L+ ++ G YD +L F+ G + GR+ + TRF S+ + ++ +PS++ L+ IY++ LK N +V+ + + + +E+Y + SKF HY+F DL++ V + L P T ++ + E++R+F DRLV+ + K G + + I + ++ + D + F + + E + ++ L E L+ +Y+ ++++LF + +++ ++ R++ G LL G G G+++ + L ++ ++ + RGY F+ DL++ G+E + ++ L D E +LELIN++L SG VP L+ +E E +L ++D A + G + S+ +F ++ + LHI+L M C++ P + W W ++ Y + N S L NS P S+ + + + +HD+ + T ++Y++FI Y R+ L++KN+ Q ++ G+ K+ EA +AEL K AEQ +L EK + L +I++ A E++ E+ + E+N ++A K + LA P ++ A+ + + SD++EIR+ PP ++ + E +L++ G + SW S + + + + D IT+ V L +F+ A S A + +V+A + Y ++I P + +L+RN +++ ++ ++ +S + + + +E + KL+ E + + AA+ L+ L +E +RW + EL L LL +A + Y + D RKE + ++ L + F + LT + E W EGL DELS++N ++ + P IDP A W+K + L+I + D +F LE+++++G + Q+VD ++PV+ +L ++ RQ + LGDK +DY+P+FKL+L T+ P+ P +N+T T GL+ QLL++ + + +LEE++ NL+QE + K L +E+SLL+ELA +TGN+L+N +L+ +L +TK + +S+ L+ + K + +D+ RD + P A+ G+ LFFV+S+++ +N+MY++SL+SFL +F +L S R +++ L VY Y C +F+ +L+F+ +M+ + D PQ E + F IS + + WI I L+ P ++ L + + W + E+ P +KLS FQK+L+++ R DR+ A+S + + K++ P ++ I+E +++ PI+ I+SPG+DP+ DL +L+ + G R +AMGQGQ + L LL G WL L+N HL+ WL LEK L + KPH DFRLW+T +P F +LQ SLK+ E P G+K N+ +Y S + + + ++ LA+FHA++QERR F GW Y+F+ +D + EIL+ + K+ + I W + L ++GGR + FD R+L++Y+ Y D + + +FY ++P +K ++ I L N+P F L N + + T+ +D+W+ EL P ++R + + Q I+ LP D ++++ + + VV +LER+N KL+ + SL+ L + L G ++ E+ ++ L GQ PN+W + + ++M + W SE + ++ L L P+++L AL Q T R +D + + + + G L++EG +D + C S VL+ + V V + + + P+Y +R +V + D+ + W+ GV L L S
Sbjct: 1262 LESKMKEFKESIPLLLDLKNEALRDRHWKELMTKTGTDFEMNPETFTLENMF--AMELHKYADAISDIVASAVKELSIEKGVKEILDTW-ENMKFTVQRYIKGTQDRGSILGTVDEILQILDDNAMNLQSISGSRFVGPFLNTVQQWEKTLSLIGEVIEVWMVVQRKWMYLESIFIGGDIRSQLPDEAKKFDNIDRIFKRIMSETVKDPVIKRCCQASNRLSDLQNLSEGLERCQKSLNDYLDSKRNAFPRFFFISDDELLSILG-SSDPTCVQEHIIKMYDNIASLKFQEGDNGEMK-ATAMVSAEGEVMPFRQVVAAEGRVEDWMTTVLQEMRRT----------NRLITKEAIFRYCEDKSRVDWMLLYQGMVVLAGNQVWWTWEVEDVFRK-----VKKGEKQALKNYAK-KMHQQIDELVTRITKPLSKNDRKKYNTVLIIDVHARDIVDIFVRDSIMDAREFEWESQLRFYWDREPDELNVRQCTGTFAYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYKAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHHLKRFQFEGQEIALDARMGIFITMNP---GYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLQAKNLAKKMTVLYKLAREQLSKQHHYDFGLRALKSVLVMAGEL--------KRGSPDLNEDV--------VLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEEALQENNYILLPTQVDKVVQMYETMLTRHTTMVVGPTGGGKSVVINTLCLAQTKLGLVTKLYTLNPKAMSVIELYGILDPATRDWTDGVLSNIFREINKPTEKKERRYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQPHCALLFEVGDLQYASPATVSRCGMVFVDPKNLKYMPYWQKWVNNRQSKQEQSVLSKLFEKYVPHCIEMIVEGITDGKQGEKLKTIVPQTDLNMVTQLSTMLDALLEKEVDDADVLECYFIEAMYWSLGATLLETGRIKFDEYIKRLASMSAAYDESILAGPGELPYQQPTIYDFHFDGEKKKWIPWSKLVPKYIH----KPEEKFIDILVPTVDTTRT-----TWLLEQMVKIKRPVVLVGESGTSKTATTLNLLRNLNTDMLLSINFSSRTTSMDIQRNLEAN---VEKRTKDNYGPPMGKRLLVFMDDMNMPKVDEYGTQQPIALLKLLLEKGGMYDRGKELNCKYLRDLGFIAAMG---------KAGGGRNEVDTRFISLFSVFNVLFPSEESLSLIYSSILKGHTALF---------NEEVQAICDKLTFCTLELYKMIVRDLPPTPSKF------HYIFNLRDLSR-VYNGLVLTTP-ERFQTVAQMVRVWRNENLRVFHDRLVNEED-KLVQGHIKHLIEEHFQASLEHATRDPILFGDYRTAMSEGEPRVYEDIQDYEAAKALFQEILE--------EYNESKTKMNLVLFDDALEHLTRIHRIIRMDRGHALLVGVGGSGKQSLARLAAYAAGYEVFEIVLSRGYGENSFREDLRNLYIKLGLENKKMIFLFTDAHVAEEGFLELINNMLTSGMVPALFPDDEKESVLSQIRDEATKHGVGPAKESIWQFFVNKSANNLHIVLGMSPVGDTLRTRCRNFPGLVNNTGIDWFLPWPPQAL----YAVAN-------SFLGDNSLIPSQH---SEPVTGHVVMVHDSVGKFSKKFQQKLRRSNYVTPKNYLDFINTYSRL-LEEKNQYNLAQCKRLEGGLDKLKEATVQLAELNVKLAEQKVVLAEKSSACEALLDEISTNTTIAEEKRKLAEEKAAEIEEQNKVIAVEKQEAESALAEALPILEAAKLELQKLDKSDVTEIRSFAKPPRAVQVVCECILVMRGYKEISWKSAKGMMSDPSFLKSLMEIDFDAITQHQVKAVRGFLKTLNTTFEEMEA--ISKAGLGMLKFVEAVMGYCDVAKEIKPKREKVAKLERNYYMSKRDLEKIQAELSTIQNELKALGEKYEAAITEKQKLQEEAEVMERRLIAADKLISGLGSENKRWTNDLEELKVRRVKLLGDCLLCSAFLSYEGAFNWDFRKEMVYTEWQQDILAREIPLSQPFRIESLLTDDVEISRWGSEGLPPDELSIQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLKISSFNDPDFLKQLEMAIKYGFPFLFQDVDEYIDPVIDNVLEKNIKGAQGRQFIILGDKEVDYDPNFKLYLNTKLSNPKYSPSVFGKAMVINYTVTLKGLEDQLLSVIVGFERRELEEQRENLIQETSENKKLLKDLEDSLLRELATSTGNMLDNVELVHTLEETKAKATEVSEKLKLAEKTAVDIDKLRDGYRPAAKRGAILFFVLSEMALVNSMYQYSLSSFLAVFDHSLRKSLPDGILMKRLKNIMDTLTYNVYNYGCTGLFEKHKLLFSFNMTVKIEQADGRVPQEELDFFLKGNISLEKSKRKKPCSWIPDQGWEDIIRLSELFPSMFGSLPSDVERCEAEWKAWYDLDTLEQYPYPLGYNDKLSDFQKLLLLRCFRVDRVYRAVSDYVTVTMGEKYVQPPVISFEAIFE-QSVPTSPIVFILSPGSDPASDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVFRGQWLMLQNCHLLVKWLKDLEKALEMIKKPHPDFRLWLTTDPTKEFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEALDSCQHSAFKSLVYVLAFFHAVVQERRKFGKIGWNVPYDFNESDFQVCMEILNTYLTKAFQQHDTKIPWGSLKYLIGEVMYGGRAIDSFDRRILTTYMDEYLGDFIFDTFQLFHFYKNEEVDYRIPEGTTKDAFVEAIESLPLANTPEVFGLHSNAEIG---------------------YYTQAARDMWTHLLELQPQTGESSTGISRDEYIGQVAKDIENKLPQIFDLDQIRKNLGLEISPTTVVLLQELERFN--KLIIRMSRSLVELQRALAGEVGMSSELDEVARALFNGQIPNIWRRLAPDTLKSLGNWMIHFRRRFNQYTSWVNESEPN-----VMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLYTQVTSFRTPEEVTERPGQGCFISGLYLEGADWD--IANSCLIKSKPKVLVVELPVLKVIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADL-YTTKHNSHWVLQGVCLTLNS 4409
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Mouse
Match: Dync2h1 (dynein cytoplasmic 2 heavy chain 1 [Source:MGI Symbol;Acc:MGI:107736]) HSP 1 Score: 4514.52 bits (11708), Expect = 0.000e+0 Identity = 2339/4344 (53.84%), Postives = 3103/4344 (71.43%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHF----------PNQNSKFVNEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPT-----KNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRN-AEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLS--ADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVS-LLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKI------PREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVV------NGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNII--KASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RK +F T+++F P N VN F D+ + +L V+ + FSN ++ D LVF K P +IT N+++ I+V+++ E+PI+SLY ++ ++ P+LL D DPK+Q L+SELE GLG ++RK + K + E GI + DE FW + S ++ R + + ++ E + S SL E +E +++D+W+ +T + +YP+SRM L+++I R +Q +L L WED Y LVKE+L I +C W+ +C L + W++Y+PH W + + + RL E+ ++RT+HE++ LP E + + F+ F + P+ YNPYTEP+WK AV ++ + I PAE I +LK E + PQQLL+ F +Y +L+ RP IS L+ ERETLLA+L K R DF +R R P+ KN S+ ++ IVW +QLE K+++ + I +L DL GF F + ++ L++ + QEQF+ W++E+ L DS + G+ ++ R+MEL DG L V+YSDRLV L+REVR LS LG+ I + A+ QKF +A+ILKQVA FYN+I+ QMI Q+ MML +A+ FE+++K+ + S K+ + W+NP+EL +I KLQ A+ + ++NR LRK H CEK+V LM IDLLRQQQ+WKD L E+R L + Q + W++H +HQLYKALE+QY +GLEALNENLPEI VDL Y+QGRLQF P FEEI++KY++EMK+FI +PNQFKG+ ++ G++ IF +I+RNA+GF+ Y KAE LF+RLSA L++ KEW+++G +D+E V+++ + D+EKNFKA+K KGKE E+LP+ +K+DC+ +NC+P+K +D LIQ +FD L+ SL+K+I+ I +D ++T ++K+L+ PQ+++EI + + ++ R I ++E N LLRTVAGGG++TVS L+ KWDKFELMMES Q+M+++QIEVMK N+ SR + + Q++ KF RW LKPG DI+++G + + IK+KK+E ++L +I+ L DC HF +E F+L I KDI+ +W+ +EE+Q GLQ++AKEDW+++R++ YLFEEFL W E+LR E + MT++LQ E+D YK IIPILK++RGE LS DHWL++FRLL +PRG +LE L +L A I+ A +K+LN +AQGEVTIREA+REL+LWG GAVF L++Y DSQN++I LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK ++WE KLA LDEYLQNLN IQRKWVYLEPIFG+ ALPKE++RF +VDEDFRSIM D+ +++RV +L + +G++N L T++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQSTNP VI+SHLKKLF GI V F+++ +HI MKSL+GEVV +++VL+++ VE WL +L EMK TL L + R S + I+ +PSQILCL+E I FT E + ++++ ++ +LV KL YT+ S +S + +LKLK+LILD +HNIDI+ QL + +W W KQ+RFY KS D C +QMVD+E YTYEYQGNAPKLV+TPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQD +KN LL + V ++ NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVIL S+GFK+AKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVL+G+ NLL K N T ++V E ++VQALR+NT+SK T+AD F++LIKDVFP ID KE+EYD L+SA+++V +E N + Q KK LE+YEQLRQR GVVIVGPSG+GKST+W++LR AL KIG+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQ++ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+ SL+ SWL+ Q + L ++ D+F K+L W+ K+N++ + TS VGTV NGLS+L K F + LI+GLGGNLN SR F V+ E P+ ++ ++ Y++ + +L +Y + E L+ D S+ IL P+I T D+QR LDYFK WL+SDT+QPFIL GPEGCGK ++L + F +L+S ++ T+HCSAQTT H+LQKL+Q C++I++NTGRVYRPK+ ERL+LYLKDINLPKLDKWGTS L++FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ +GR L+TRFTSIVRLC+I YP ++QL IY AYL+ VL + + H IW +SK+ LLA +M++VY Q+++KFTVD+YSHY FTP LTQWVL L RYDL S N + +LEIV+YE+ R+F+D++V D IL + + +W ++ D++ D ++VTWG+ P GK LGKLTS LKD I +GL+ Y R+ ++LDI+LF+EV + ++++DRVL+ PGGS+LLAG+SGVGRRT + LVSHMH L SPK+ RGYE KQF+NDLK LQ AG+E + +VLLLED+QF+ P +LE+INSLLASGEVPGLYT EELEP+L+ LKD A++ G G + NYF RI+ LHI+LIMD +NLNF++NC+SNPA K C V W+E WS SM KIP ML ++ ++ + +NS P D + S+ L +H++C +T Y+ F+ +Y I KK E+ RQ+H+Q G+ K++EAK +V EL KA EQS LL KQ EAD AL++IT MQ A+E+K E+E+L + EE V + +RK+ IDDEL ++P V +A+ AV +I+ LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+I TFDAR I +E R VEELL + K SFDPKNAKRAS AAAPLAAWVKANV+YS+ LE+I PLE EQ+ L+ NL+ E + + LE ++ V + V+ ++ F+ T++AAKLE E+ A ETI AAE L+ +L+ E RWN Q+ E+ EL+ L ++ LAAA + Y+ ++PE RK ++ W + GLEKFD+R+FL TE EQL WK EGL SD+LS+ENALVILQ + PFLIDPSS AT WLK H KD LE++NQQDSNF T LEL+VRFGKTLIIQE+DG+EPVLYPLLR DL++QGPR VVQ+GDK+IDYN DF+LFL+TRNP P +PPDA +IV+ VNFTTT++GL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+++EESLL+ LA + GNIL NKDL+ SLN+TK SS I SL+ES KLQ+SLD+ERDA+LPLAE S ++F+ISDLSKINNMYRFSL SFLRLFQRAL + S ++ R L+ L+ +VYEY+CR +FK+D+LMFALH P+LF+ EW+ FTG + D K+D + P WID +R+ A++ L ++P L+ L ++D W + S CE+E P L K+SLFQ++L++QALRPDRLQSA++ F C L LK LSP +NL ++Y+ ET+ EPILIIISPGADPSQ+LQEL++ SE Y+QVAMGQGQAD+ + +L +C++NGDWLCLKNLHLV SWLPVLEKELN+L+P FRLW+TAE H F+ ILLQSSLKITYE+PPG+K NL+R+Y++W+ + ISK + RA+ALFSLAWFHA QERRN+IPQGWTKFYEFS++DLRAG ++D++ +++QW+F+HGL EN+I+GGRVDN FD+RVL SY+K++FN S++ N F I LP++ S DY A+I +L + + PSFF LP NI RSSQR+ISSQVI QLRIL R G KFD++IWS EL+PVLN WK LNQ N+I K S P+ + SP+++F+ LE++N+I+LV+ VH SL +LSKV++G+ LL+ EVQ L+ LL + P W +WEGPE+P Y+R L+ + A++ W E +EK LL+ LDL ELFHPDTFLNALRQ TAR S+D LKFV W G AK +KI L +EGC FDG ++E DS S+ + P +GW + YS D+ ISLP+Y R+++VT ID+PC G QD+WIQ G ALFLK+
Sbjct: 7 DVRKLFLFTTTQNYFGLRPELWDQPPLSNCPEVN-----NFLDDGNQMLLRVQRSEAGLAFSNTIDFDDAKDKVLVFFKLRPEVITDGNLHNNILVSSMLESPINSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRKSDTNLPKLKLKEDDTRGILTPSDEFQFWIEQAHRGSKQISKERASYFKELFETISREFYNLDSLSLLEVVDLVETTRDVVDDVWR-QTEHDHYPESRMLHLLDVIGGSFGRFVQKKLGSLKLWEDPYYLVKENLKAGISICEQWVIVCSHLTGQVWQRYVPHPWKSGKYFPET-LDKLGKRLEEVLAIRTIHEKLLYFLPASEERIVCLSRVFEPFTGVNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDS--PQQLLQAFLKYKELVKRPTISKELMLERETLLARLGDSAKDFRLDFENRCRGIPGDPSGPLSGKNLSEVVNNIVWVRQLELKVDDTIKIAEALLSDLSGFRSFHRSAEDLLDQFKLYEQEQFDDWSREVQSGLSDSRS-GLCIEANSRIMELDPNDGALKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANVAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRRLRKWHTTFCEKVVILMNIDLLRQQQRWKDGLQELRTGLATVAAQGFQASDMRAWRQHWNHQLYKALEHQYQVGLEALNENLPEINVDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEA--GDESIFSVMIDRNASGFLTIYSKAEDLFRRLSAVLHQHKEWVVIGQVDMEALVEKNLSTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCSPVKTVIDDLIQKLFDLLVLSLKKSIQTHIHEIDTFVTEAMKVLTVIPQSVEEIGDTNVQYSNLQDRRPEILPLFQEAEDKNRLLRTVAGGGVETVSNLRAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELDKFKARWDQLKPGDDIIETGQQNTMDQSAKSIKEKKIEFDDLEVIRKKLVDDCHHFGLEEPNFSLAYSISKDIESCAQIWALYEEFQQGLQDMAKEDWITYRAKIYLFEEFLINWHERLRKIEEHSVMTVKLQSEVDRYKMIIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVEKASELKDLNSRAQGEVTIREALRELDLWGVGAVFSLIDYEDSQNHTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAQLDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNKVDEDFRSIMMDIRKDSRVTTLTTHAGIRNTLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEESKHITAMKSLEGEVVPFKSKVLLSNNVEAWLNDLALEMKQTLKQLLKECVTAGRSSQGA---IDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIEAQLVAKLERYTSVDTSSEDPGNSESGILELKLKALILDIIHNIDIVKQLNQVQVHTTDDWAWKKQVRFYMKS-DHTCYVQMVDSELQYTYEYQGNAPKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRTVCELLGKEVEINANSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILYSEGFKDAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLKK------NSTKQDVN----ENHIVVQALRLNTMSKFTFADCTRFDALIKDVFPGIDFKEVEYDELSSALKQVFEEANYEVIPNQMKKALELYEQLRQRTGVVIVGPSGAGKSTLWRMLRAALCKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPLEYRSNLENWIGDYFSKALQWVLKQNDYVVETSLVGTVMNGLSHLHGCKYHDQFIINLIRGLGGNLNMKSRLEFTKEVFNWARETPPDSHRP--MDTYYDCDRGQLASYMLKKPESLTADDF-SNGHIL-PVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTEIATIHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCAIDYPEREQLQTIYGAYLEAVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDEYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGVKELHLFDNILTSVLQGDWGSDILDNMADSFYVTWGAHHVSGGKTAPGQPLPPHGKPLGKLTSADLKDVIKKGLIHYGRDNQNLDILLFQEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTVTSLVSHMHGAVLFSPKISRGYEPKQFRNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLASGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANLNFIVNCESNPALHKKCQVLWMEGWSDSSMKKIPEMLFSETDGEEKYEKKRKDEKKRNSVDP-------DFIKSFLL-IHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSILLRIKQDEADSALQEITVSMQDASEQKTELERLKQRIAEEVVKIEERKSKIDDELKEVQPLVNEAKLAVGNIRPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNIPKEIRESVEELLFKNKASFDPKNAKRASTAAAPLAAWVKANVQYSHVLERIQPLETEQSGLELNLKKTEDRKRKLEDLLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLISQLDREHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKAAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSHLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEDFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLARLEESLLETLATSQGNILENKDLIESLNQTKASSALIQDSLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLASFLRLFQRALQNKQDSENTEERIQCLVNSLKHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQRIRDQLPSWIDQERSWAVATLKISLPSLYQTLCLEDGAFWRTYYHHSMCEQEFPSILAKKVSLFQQVLVVQALRPDRLQSAMALFACKALGLKELSPLPLNLKRLYK-ETLEIEPILIIISPGADPSQELQELASAERSSECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDSFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKRDNIHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYHVIDRLF-DGTKDVQWEFVHGLLENSIYGGRVDNYFDLRVLQSYLKQFFNSSIIDVLNQRNKKSIFPYSISLPNSCSILDYRAVIEKLPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSVTAGCKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVSPPNDRQ----GSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLTWQSRWEGPEDPLQYLRGLVARTLAIQNWVEKAEKQVLLADTLDLSELFHPDTFLNALRQETARATGCSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNRLSENQHDSPSVSSVLPCYMGWTPQGSYGPYSPDECISLPVYTSAERERVVTNIDVPC-GGNQDQWIQCGAALFLKN 4305
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Mouse
Match: Dync2h1 (dynein cytoplasmic 2 heavy chain 1 [Source:MGI Symbol;Acc:MGI:107736]) HSP 1 Score: 4514.52 bits (11708), Expect = 0.000e+0 Identity = 2339/4344 (53.84%), Postives = 3103/4344 (71.43%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHF----------PNQNSKFVNEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPT-----KNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRN-AEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLS--ADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVS-LLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKI------PREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVV------NGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNII--KASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RK +F T+++F P N VN F D+ + +L V+ + FSN ++ D LVF K P +IT N+++ I+V+++ E+PI+SLY ++ ++ P+LL D DPK+Q L+SELE GLG ++RK + K + E GI + DE FW + S ++ R + + ++ E + S SL E +E +++D+W+ +T + +YP+SRM L+++I R +Q +L L WED Y LVKE+L I +C W+ +C L + W++Y+PH W + + + RL E+ ++RT+HE++ LP E + + F+ F + P+ YNPYTEP+WK AV ++ + I PAE I +LK E + PQQLL+ F +Y +L+ RP IS L+ ERETLLA+L K R DF +R R P+ KN S+ ++ IVW +QLE K+++ + I +L DL GF F + ++ L++ + QEQF+ W++E+ L DS + G+ ++ R+MEL DG L V+YSDRLV L+REVR LS LG+ I + A+ QKF +A+ILKQVA FYN+I+ QMI Q+ MML +A+ FE+++K+ + S K+ + W+NP+EL +I KLQ A+ + ++NR LRK H CEK+V LM IDLLRQQQ+WKD L E+R L + Q + W++H +HQLYKALE+QY +GLEALNENLPEI VDL Y+QGRLQF P FEEI++KY++EMK+FI +PNQFKG+ ++ G++ IF +I+RNA+GF+ Y KAE LF+RLSA L++ KEW+++G +D+E V+++ + D+EKNFKA+K KGKE E+LP+ +K+DC+ +NC+P+K +D LIQ +FD L+ SL+K+I+ I +D ++T ++K+L+ PQ+++EI + + ++ R I ++E N LLRTVAGGG++TVS L+ KWDKFELMMES Q+M+++QIEVMK N+ SR + + Q++ KF RW LKPG DI+++G + + IK+KK+E ++L +I+ L DC HF +E F+L I KDI+ +W+ +EE+Q GLQ++AKEDW+++R++ YLFEEFL W E+LR E + MT++LQ E+D YK IIPILK++RGE LS DHWL++FRLL +PRG +LE L +L A I+ A +K+LN +AQGEVTIREA+REL+LWG GAVF L++Y DSQN++I LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK ++WE KLA LDEYLQNLN IQRKWVYLEPIFG+ ALPKE++RF +VDEDFRSIM D+ +++RV +L + +G++N L T++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQSTNP VI+SHLKKLF GI V F+++ +HI MKSL+GEVV +++VL+++ VE WL +L EMK TL L + R S + I+ +PSQILCL+E I FT E + ++++ ++ +LV KL YT+ S +S + +LKLK+LILD +HNIDI+ QL + +W W KQ+RFY KS D C +QMVD+E YTYEYQGNAPKLV+TPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQD +KN LL + V ++ NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVIL S+GFK+AKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVL+G+ NLL K N T ++V E ++VQALR+NT+SK T+AD F++LIKDVFP ID KE+EYD L+SA+++V +E N + Q KK LE+YEQLRQR GVVIVGPSG+GKST+W++LR AL KIG+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQ++ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+ SL+ SWL+ Q + L ++ D+F K+L W+ K+N++ + TS VGTV NGLS+L K F + LI+GLGGNLN SR F V+ E P+ ++ ++ Y++ + +L +Y + E L+ D S+ IL P+I T D+QR LDYFK WL+SDT+QPFIL GPEGCGK ++L + F +L+S ++ T+HCSAQTT H+LQKL+Q C++I++NTGRVYRPK+ ERL+LYLKDINLPKLDKWGTS L++FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ +GR L+TRFTSIVRLC+I YP ++QL IY AYL+ VL + + H IW +SK+ LLA +M++VY Q+++KFTVD+YSHY FTP LTQWVL L RYDL S N + +LEIV+YE+ R+F+D++V D IL + + +W ++ D++ D ++VTWG+ P GK LGKLTS LKD I +GL+ Y R+ ++LDI+LF+EV + ++++DRVL+ PGGS+LLAG+SGVGRRT + LVSHMH L SPK+ RGYE KQF+NDLK LQ AG+E + +VLLLED+QF+ P +LE+INSLLASGEVPGLYT EELEP+L+ LKD A++ G G + NYF RI+ LHI+LIMD +NLNF++NC+SNPA K C V W+E WS SM KIP ML ++ ++ + +NS P D + S+ L +H++C +T Y+ F+ +Y I KK E+ RQ+H+Q G+ K++EAK +V EL KA EQS LL KQ EAD AL++IT MQ A+E+K E+E+L + EE V + +RK+ IDDEL ++P V +A+ AV +I+ LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+I TFDAR I +E R VEELL + K SFDPKNAKRAS AAAPLAAWVKANV+YS+ LE+I PLE EQ+ L+ NL+ E + + LE ++ V + V+ ++ F+ T++AAKLE E+ A ETI AAE L+ +L+ E RWN Q+ E+ EL+ L ++ LAAA + Y+ ++PE RK ++ W + GLEKFD+R+FL TE EQL WK EGL SD+LS+ENALVILQ + PFLIDPSS AT WLK H KD LE++NQQDSNF T LEL+VRFGKTLIIQE+DG+EPVLYPLLR DL++QGPR VVQ+GDK+IDYN DF+LFL+TRNP P +PPDA +IV+ VNFTTT++GL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+++EESLL+ LA + GNIL NKDL+ SLN+TK SS I SL+ES KLQ+SLD+ERDA+LPLAE S ++F+ISDLSKINNMYRFSL SFLRLFQRAL + S ++ R L+ L+ +VYEY+CR +FK+D+LMFALH P+LF+ EW+ FTG + D K+D + P WID +R+ A++ L ++P L+ L ++D W + S CE+E P L K+SLFQ++L++QALRPDRLQSA++ F C L LK LSP +NL ++Y+ ET+ EPILIIISPGADPSQ+LQEL++ SE Y+QVAMGQGQAD+ + +L +C++NGDWLCLKNLHLV SWLPVLEKELN+L+P FRLW+TAE H F+ ILLQSSLKITYE+PPG+K NL+R+Y++W+ + ISK + RA+ALFSLAWFHA QERRN+IPQGWTKFYEFS++DLRAG ++D++ +++QW+F+HGL EN+I+GGRVDN FD+RVL SY+K++FN S++ N F I LP++ S DY A+I +L + + PSFF LP NI RSSQR+ISSQVI QLRIL R G KFD++IWS EL+PVLN WK LNQ N+I K S P+ + SP+++F+ LE++N+I+LV+ VH SL +LSKV++G+ LL+ EVQ L+ LL + P W +WEGPE+P Y+R L+ + A++ W E +EK LL+ LDL ELFHPDTFLNALRQ TAR S+D LKFV W G AK +KI L +EGC FDG ++E DS S+ + P +GW + YS D+ ISLP+Y R+++VT ID+PC G QD+WIQ G ALFLK+
Sbjct: 7 DVRKLFLFTTTQNYFGLRPELWDQPPLSNCPEVN-----NFLDDGNQMLLRVQRSEAGLAFSNTIDFDDAKDKVLVFFKLRPEVITDGNLHNNILVSSMLESPINSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRKSDTNLPKLKLKEDDTRGILTPSDEFQFWIEQAHRGSKQISKERASYFKELFETISREFYNLDSLSLLEVVDLVETTRDVVDDVWR-QTEHDHYPESRMLHLLDVIGGSFGRFVQKKLGSLKLWEDPYYLVKENLKAGISICEQWVIVCSHLTGQVWQRYVPHPWKSGKYFPET-LDKLGKRLEEVLAIRTIHEKLLYFLPASEERIVCLSRVFEPFTGVNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDS--PQQLLQAFLKYKELVKRPTISKELMLERETLLARLGDSAKDFRLDFENRCRGIPGDPSGPLSGKNLSEVVNNIVWVRQLELKVDDTIKIAEALLSDLSGFRSFHRSAEDLLDQFKLYEQEQFDDWSREVQSGLSDSRS-GLCIEANSRIMELDPNDGALKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANVAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRRLRKWHTTFCEKVVILMNIDLLRQQQRWKDGLQELRTGLATVAAQGFQASDMRAWRQHWNHQLYKALEHQYQVGLEALNENLPEINVDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEA--GDESIFSVMIDRNASGFLTIYSKAEDLFRRLSAVLHQHKEWVVIGQVDMEALVEKNLSTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCSPVKTVIDDLIQKLFDLLVLSLKKSIQTHIHEIDTFVTEAMKVLTVIPQSVEEIGDTNVQYSNLQDRRPEILPLFQEAEDKNRLLRTVAGGGVETVSNLRAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELDKFKARWDQLKPGDDIIETGQQNTMDQSAKSIKEKKIEFDDLEVIRKKLVDDCHHFGLEEPNFSLAYSISKDIESCAQIWALYEEFQQGLQDMAKEDWITYRAKIYLFEEFLINWHERLRKIEEHSVMTVKLQSEVDRYKMIIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVEKASELKDLNSRAQGEVTIREALRELDLWGVGAVFSLIDYEDSQNHTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAQLDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNKVDEDFRSIMMDIRKDSRVTTLTTHAGIRNTLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEESKHITAMKSLEGEVVPFKSKVLLSNNVEAWLNDLALEMKQTLKQLLKECVTAGRSSQGA---IDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIEAQLVAKLERYTSVDTSSEDPGNSESGILELKLKALILDIIHNIDIVKQLNQVQVHTTDDWAWKKQVRFYMKS-DHTCYVQMVDSELQYTYEYQGNAPKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRTVCELLGKEVEINANSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILYSEGFKDAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLKK------NSTKQDVN----ENHIVVQALRLNTMSKFTFADCTRFDALIKDVFPGIDFKEVEYDELSSALKQVFEEANYEVIPNQMKKALELYEQLRQRTGVVIVGPSGAGKSTLWRMLRAALCKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPLEYRSNLENWIGDYFSKALQWVLKQNDYVVETSLVGTVMNGLSHLHGCKYHDQFIINLIRGLGGNLNMKSRLEFTKEVFNWARETPPDSHRP--MDTYYDCDRGQLASYMLKKPESLTADDF-SNGHIL-PVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTEIATIHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCAIDYPEREQLQTIYGAYLEAVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDEYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGVKELHLFDNILTSVLQGDWGSDILDNMADSFYVTWGAHHVSGGKTAPGQPLPPHGKPLGKLTSADLKDVIKKGLIHYGRDNQNLDILLFQEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTVTSLVSHMHGAVLFSPKISRGYEPKQFRNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLASGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANLNFIVNCESNPALHKKCQVLWMEGWSDSSMKKIPEMLFSETDGEEKYEKKRKDEKKRNSVDP-------DFIKSFLL-IHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSILLRIKQDEADSALQEITVSMQDASEQKTELERLKQRIAEEVVKIEERKSKIDDELKEVQPLVNEAKLAVGNIRPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNIPKEIRESVEELLFKNKASFDPKNAKRASTAAAPLAAWVKANVQYSHVLERIQPLETEQSGLELNLKKTEDRKRKLEDLLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLISQLDREHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKAAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSHLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEDFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLARLEESLLETLATSQGNILENKDLIESLNQTKASSALIQDSLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLASFLRLFQRALQNKQDSENTEERIQCLVNSLKHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQRIRDQLPSWIDQERSWAVATLKISLPSLYQTLCLEDGAFWRTYYHHSMCEQEFPSILAKKVSLFQQVLVVQALRPDRLQSAMALFACKALGLKELSPLPLNLKRLYK-ETLEIEPILIIISPGADPSQELQELASAERSSECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDSFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKRDNIHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYHVIDRLF-DGTKDVQWEFVHGLLENSIYGGRVDNYFDLRVLQSYLKQFFNSSIIDVLNQRNKKSIFPYSISLPNSCSILDYRAVIEKLPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSVTAGCKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVSPPNDRQ----GSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLTWQSRWEGPEDPLQYLRGLVARTLAIQNWVEKAEKQVLLADTLDLSELFHPDTFLNALRQETARATGCSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNRLSENQHDSPSVSSVLPCYMGWTPQGSYGPYSPDECISLPVYTSAERERVVTNIDVPC-GGNQDQWIQCGAALFLKN 4305
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Mouse
Match: Dync2h1 (dynein cytoplasmic 2 heavy chain 1 [Source:MGI Symbol;Acc:MGI:107736]) HSP 1 Score: 4509.9 bits (11696), Expect = 0.000e+0 Identity = 2340/4351 (53.78%), Postives = 3104/4351 (71.34%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHF----------PNQNSKFVNEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPT-----KNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRN-AEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLS--ADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVS-LLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKI------PREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGI-------LIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVV------NGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNII--KASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RK +F T+++F P N VN F D+ + +L V+ + FSN ++ D LVF K P +IT N+++ I+V+++ E+PI+SLY ++ ++ P+LL D DPK+Q L+SELE GLG ++RK + K + E GI + DE FW + S ++ R + + ++ E + S SL E +E +++D+W+ +T + +YP+SRM L+++I R +Q +L L WED Y LVKE+L I +C W+ +C L + W++Y+PH W + + + RL E+ ++RT+HE++ LP E + + F+ F + P+ YNPYTEP+WK AV ++ + I PAE I +LK E + PQQLL+ F +Y +L+ RP IS L+ ERETLLA+L K R DF +R R P+ KN S+ ++ IVW +QLE K+++ + I +L DL GF F + ++ L++ + QEQF+ W++E+ L DS + G+ ++ R+MEL DG L V+YSDRLV L+REVR LS LG+ I + A+ QKF +A+ILKQVA FYN+I+ QMI Q+ MML +A+ FE+++K+ + S K+ + W+NP+EL +I KLQ A+ + ++NR LRK H CEK+V LM IDLLRQQQ+WKD L E+R L + Q + W++H +HQLYKALE+QY +GLEALNENLPEI VDL Y+QGRLQF P FEEI++KY++EMK+FI +PNQFKG+ ++ G++ IF +I+RNA+GF+ Y KAE LF+RLSA L++ KEW+++G +D+E V+++ + D+EKNFKA+K KGKE E+LP+ +K+DC+ +NC+P+K +D LIQ +FD L+ SL+K+I+ I +D ++T ++K+L+ PQ+++EI + + ++ R I ++E N LLRTVAGGG++TVS L+ KWDKFELMMES Q+M+++QIEVMK N+ SR + + Q++ KF RW LKPG DI+++G + + IK+KK+E ++L +I+ L DC HF +E F+L I KDI+ +W+ +EE+Q GLQ++AKEDW+++R++ YLFEEFL W E+LR E + MT++LQ E+D YK IIPILK++RGE LS DHWL++FRLL +PRG +LE L +L A I+ A +K+LN +AQGEVTIREA+REL+LWG GAVF L++Y DSQN++I LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK ++WE KLA LDEYLQNLN IQRKWVYLEPIFG+ ALPKE++RF +VDEDFRSIM D+ +++RV +L + +G++N L T++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQSTNP VI+SHLKKLF GI V F+++ +HI MKSL+GEVV +++VL+++ VE WL +L EMK TL L + R S + I+ +PSQILCL+E I FT E + ++++ ++ +LV KL YT+ S +S + +LKLK+LILD +HNIDI+ QL + +W W KQ+RFY KS D C +QMVD+E YTYEYQGNAPKLV+TPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQD +KN LL + V ++ NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVIL S+GFK+AKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVL+G+ NLL K N T ++V E ++VQALR+NT+SK T+AD F++LIKDVFP ID KE+EYD L+SA+++V +E N + Q KK LE+YEQLRQR GVVIVGPSG+GKST+W++LR AL KIG+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQ++ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+ SL+ SWL+ Q + L ++ D+F K+L W+ K+N++ + TS VGTV NGLS+L K F + LI+GLGGNLN SR F V+ E P+ ++ ++ Y++ + +L +Y + E L+ D S+ IL P+I T D+QR LDYFK WL+SDT+QPFIL GPEGCGK ++L + F +L+S ++ T+HCSAQTT H+LQKL+Q C++I++NTGRVYRPK+ ERL+LYLKDINLPKLDKWGTS L++FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ +GR L+TRFTSIVRLC+I YP ++QL IY AYL+ VL + + H IW +SK+ LLA +M++VY Q+++KFTVD+YSHY FTP LTQWVL L RYDL S N + +LEIV+YE+ R+F+D++V D IL + + +W ++ D++ D ++VTWG+ P GK LGKLTS LKD I +GL+ Y R+ ++LDI+LF+EV + ++++DRVL+ PGGS+LLAG+SGVGRRT + LVSHMH L SPK+ RGYE KQF+NDLK LQ AG+E + +VLLLED+QF+ P +LE+INSLLASGEVPGLYT EELEP+L+ LKD A++ G G + NYF RI+ LHI+LIMD +NLNF++NC+SNPA K C V W+E WS SM KIP ML ++ ++ + +NS P D + S+ L +H++C +T Y+ F+ +Y I KK E+ RQ+H+Q G+ K++EAK +V EL KA EQS LL KQ EAD AL++IT MQ A+E+K E+E+L + EE V + +RK+ IDDEL ++P V +A+ AV +I+ LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+I TFDAR I +E R VEELL + K SFDPKNAKRAS AAAPLAAWVKANV+YS+ LE+I PLE EQ+ L+ NL+ E + + LE ++ V + V+ ++ F+ T++AAKLE E+ A ETI AAE L+ +L+ E RWN Q+ E+ EL+ L ++ LAAA + Y+ ++PE RK ++ W + GLEKFD+R+FL TE EQL WK EGL SD+LS+ENALVILQ I + PFLIDPSS AT WLK H KD LE++NQQDSNF T LEL+VRFGKTLIIQE+DG+EPVLYPLLR DL++QGPR VVQ+GDK+IDYN DF+LFL+TRNP P +PPDA +IV+ VNFTTT++GL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+++EESLL+ LA + GNIL NKDL+ SLN+TK SS I SL+ES KLQ+SLD+ERDA+LPLAE S ++F+ISDLSKINNMYRFSL SFLRLFQRAL + S ++ R L+ L+ +VYEY+CR +FK+D+LMFALH P+LF+ EW+ FTG + D K+D + P WID +R+ A++ L ++P L+ L ++D W + S CE+E P L K+SLFQ++L++QALRPDRLQSA++ F C L LK LSP +NL ++Y+ ET+ EPILIIISPGADPSQ+LQEL++ SE Y+QVAMGQGQAD+ + +L +C++NGDWLCLKNLHLV SWLPVLEKELN+L+P FRLW+TAE H F+ ILLQSSLKITYE+PPG+K NL+R+Y++W+ + ISK + RA+ALFSLAWFHA QERRN+IPQGWTKFYEFS++DLRAG ++D++ +++QW+F+HGL EN+I+GGRVDN FD+RVL SY+K++FN S++ N F I LP++ S DY A+I +L + + PSFF LP NI RSSQR+ISSQVI QLRIL R G KFD++IWS EL+PVLN WK LNQ N+I K S P+ + SP+++F+ LE++N+I+LV+ VH SL +LSKV++G+ LL+ EVQ L+ LL + P W +WEGPE+P Y+R L+ + A++ W E +EK LL+ LDL ELFHPDTFLNALRQ TAR S+D LKFV W G AK +KI L +EGC FDG ++E DS S+ + P +GW + YS D+ ISLP+Y R+++VT ID+PC G QD+WIQ G ALFLK+
Sbjct: 7 DVRKLFLFTTTQNYFGLRPELWDQPPLSNCPEVN-----NFLDDGNQMLLRVQRSEAGLAFSNTIDFDDAKDKVLVFFKLRPEVITDGNLHNNILVSSMLESPINSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRKSDTNLPKLKLKEDDTRGILTPSDEFQFWIEQAHRGSKQISKERASYFKELFETISREFYNLDSLSLLEVVDLVETTRDVVDDVWR-QTEHDHYPESRMLHLLDVIGGSFGRFVQKKLGSLKLWEDPYYLVKENLKAGISICEQWVIVCSHLTGQVWQRYVPHPWKSGKYFPET-LDKLGKRLEEVLAIRTIHEKLLYFLPASEERIVCLSRVFEPFTGVNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDS--PQQLLQAFLKYKELVKRPTISKELMLERETLLARLGDSAKDFRLDFENRCRGIPGDPSGPLSGKNLSEVVNNIVWVRQLELKVDDTIKIAEALLSDLSGFRSFHRSAEDLLDQFKLYEQEQFDDWSREVQSGLSDSRS-GLCIEANSRIMELDPNDGALKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANVAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRRLRKWHTTFCEKVVILMNIDLLRQQQRWKDGLQELRTGLATVAAQGFQASDMRAWRQHWNHQLYKALEHQYQVGLEALNENLPEINVDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEA--GDESIFSVMIDRNASGFLTIYSKAEDLFRRLSAVLHQHKEWVVIGQVDMEALVEKNLSTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCSPVKTVIDDLIQKLFDLLVLSLKKSIQTHIHEIDTFVTEAMKVLTVIPQSVEEIGDTNVQYSNLQDRRPEILPLFQEAEDKNRLLRTVAGGGVETVSNLRAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELDKFKARWDQLKPGDDIIETGQQNTMDQSAKSIKEKKIEFDDLEVIRKKLVDDCHHFGLEEPNFSLAYSISKDIESCAQIWALYEEFQQGLQDMAKEDWITYRAKIYLFEEFLINWHERLRKIEEHSVMTVKLQSEVDRYKMIIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVEKASELKDLNSRAQGEVTIREALRELDLWGVGAVFSLIDYEDSQNHTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAQLDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNKVDEDFRSIMMDIRKDSRVTTLTTHAGIRNTLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEESKHITAMKSLEGEVVPFKSKVLLSNNVEAWLNDLALEMKQTLKQLLKECVTAGRSSQGA---IDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIEAQLVAKLERYTSVDTSSEDPGNSESGILELKLKALILDIIHNIDIVKQLNQVQVHTTDDWAWKKQVRFYMKS-DHTCYVQMVDSELQYTYEYQGNAPKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRTVCELLGKEVEINANSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILYSEGFKDAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLKK------NSTKQDVN----ENHIVVQALRLNTMSKFTFADCTRFDALIKDVFPGIDFKEVEYDELSSALKQVFEEANYEVIPNQMKKALELYEQLRQRTGVVIVGPSGAGKSTLWRMLRAALCKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPLEYRSNLENWIGDYFSKALQWVLKQNDYVVETSLVGTVMNGLSHLHGCKYHDQFIINLIRGLGGNLNMKSRLEFTKEVFNWARETPPDSHRP--MDTYYDCDRGQLASYMLKKPESLTADDF-SNGHIL-PVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTEIATIHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCAIDYPEREQLQTIYGAYLEAVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDEYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGVKELHLFDNILTSVLQGDWGSDILDNMADSFYVTWGAHHVSGGKTAPGQPLPPHGKPLGKLTSADLKDVIKKGLIHYGRDNQNLDILLFQEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTVTSLVSHMHGAVLFSPKISRGYEPKQFRNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLASGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANLNFIVNCESNPALHKKCQVLWMEGWSDSSMKKIPEMLFSETDGEEKYEKKRKDEKKRNSVDP-------DFIKSFLL-IHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSILLRIKQDEADSALQEITVSMQDASEQKTELERLKQRIAEEVVKIEERKSKIDDELKEVQPLVNEAKLAVGNIRPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNIPKEIRESVEELLFKNKASFDPKNAKRASTAAAPLAAWVKANVQYSHVLERIQPLETEQSGLELNLKKTEDRKRKLEDLLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLISQLDREHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKAAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSHLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEDFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLARLEESLLETLATSQGNILENKDLIESLNQTKASSALIQDSLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLASFLRLFQRALQNKQDSENTEERIQCLVNSLKHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQRIRDQLPSWIDQERSWAVATLKISLPSLYQTLCLEDGAFWRTYYHHSMCEQEFPSILAKKVSLFQQVLVVQALRPDRLQSAMALFACKALGLKELSPLPLNLKRLYK-ETLEIEPILIIISPGADPSQELQELASAERSSECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDSFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKRDNIHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYHVIDRLF-DGTKDVQWEFVHGLLENSIYGGRVDNYFDLRVLQSYLKQFFNSSIIDVLNQRNKKSIFPYSISLPNSCSILDYRAVIEKLPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSVTAGCKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVSPPNDRQ----GSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLTWQSRWEGPEDPLQYLRGLVARTLAIQNWVEKAEKQVLLADTLDLSELFHPDTFLNALRQETARATGCSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNRLSENQHDSPSVSSVLPCYMGWTPQGSYGPYSPDECISLPVYTSAERERVVTNIDVPC-GGNQDQWIQCGAALFLKN 4312
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Mouse
Match: Dnah2 (dynein, axonemal, heavy chain 2 [Source:MGI Symbol;Acc:MGI:107731]) HSP 1 Score: 1235.32 bits (3195), Expect = 0.000e+0 Identity = 984/3538 (27.81%), Postives = 1714/3538 (48.45%), Query Frame = 3
Query: 2772 IKIDCITVNCAPIKMSVDTLI---QNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTV----SQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNL---------EKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEE--YQTGLQNLAKEDWLS--FRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGI-----YDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLR-MSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKEL-VKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQT-------VKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDW-------IAKRNEFT--ISTSNVGTVY----NGLSNLKA----IKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQ--VTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIE----VYSQLKSKFTVDDYS-HYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQY--SRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSY----FLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISE--------------AKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRC-KDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKM-QLWMEK------TGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF--TGTFISDKSDRNITVPKWI-DA--DRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLK---PHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSE-DFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFY-----GKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSST-------DSP--VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNV--SAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYY------DILRDKIVTKIDIPCQSGQQDKWIQSGVALFL 12986
+ I + ++C+ +K S+ QN F LL + G + + +YL ++ + +S PQ ++E+ + D + +QI + +L DTV L +W F+ ++ + M+++ E KT ++ F++ + ++ P + G T A Q +E +++NL KD + + E + + EI +D +++ W+Q++ +QT LQ A E FR L +E+ K RN EI T + +I+ +K +P++ +R L + HW ++ + E+ TL I+ + +H E I E++ A E+ I ++ + +V Y D ++ + +E + + DNQ L ++K S + + F+ WE L+ + E ++ + +QR+W+YLE IF + LP E + F +V+ ++++IM +N++N L G+ L M L+ QK+L+ YLE KR +FPRFYF+ +DDLLEILGQS NP+ ++ HLKK F I V + + M S DGE ++ + VL+ VE+WLG++ M+ TL D L L+ N+ + + + Q++ + I +TA + L + KK L V LN Y+ A + + T I+ LK+ +L+ +H D++++L V+ ++WL QLRFY + C+I+ + +F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC EG+D KSMGR++ GL + G+WGCFDEFNR+ VLS V+ QI I + + +N+ + IFIT+NP GY GR +LP+NLK +FRP+AM PD+ LIAE+IL +GF N K L +K+ +++L+ + L+ Q HYD+GLRAL ++L+ A K + Q + + E V ++ ++R ++KLT D F ++++D+FPNI++ I+Y L IE+ I+E + K+L++YE R +IVG +GS K+T WK+L+ +L + + V+ + +NPKA+ +L G D++T EW+DG+L+ R + + + WI+ DG +D WIES+NSV+DDN++LT+ +GERI V+ +FE +L+ ASPAT+SR GM++ K V SWL+K+ + + L + F K L + + E++ IS + TV NG++ A + F +I + +++E+ R+ ++ E+ + P NK V YY N K ++ + + KI+ P T D R +Y L ++ Q P +L GP G GK+ + Q L S Q V ++ SAQTT +V + + T VY P + +I ++ D+N+P D +G+ + ++ I Y +YD + + + + GR+ +S R S + ++++P++ Q+ I+ + L+ +VK + N + E VY+ + +F HYLF D+++ +LR + +++ L I +E R+F DRLV + + GIL + + + + + + +G P + L LT LK ++ L +Y S + ++LF+E +++ ++ RV+ +P G++LL G G GR++ + L S + + ++ + Y ++F++D+K + AGVE + L D Q + +LE IN++L+SGEVP LY ++E E I + D A SL Y +R+++ LHI+L + F + PA ++ W +W R+++L++ I I + G+Q + + +T ++ Y L+L + T +Y+ + Y ++ +K+ E+ + N ++ G+ KI E AK+ VAE + + E ++ +++ EAD+ K +T A K +E++ + +N A D E AL P +++A A+ + D+ EI++ PP + +++ V+++ G + +W + LG++ + + FD I+ + ++++ C + F P R S+AA L WV+A Y + P N L+ + + + ++ + +V + + +K +++ A +L + + + A LV L E RW + + L +L L L+AAA + YM + R E + Q+W+ K +F + FLT + +W +GL SD S EN +++ +G +IDP A W+KN ++ L+I++ Q ++ VLE +++FG +++Q V + L+P L P+L + G R ++++GDK ++YNP+F+ +L T+ P P+ A + VNF + GL+ QLL + ++ +P+LEE+K +L+ K +L ++E+ +L+ L ATG++L++ L+ +L +K ++ +++ LE S ++++D R+A+ P A+ S LFFV++D+ +I+ MY+FSL +++ LF +++ S S R L VY Y CR++F+ +L+F+ HM C + E+ F G + + + W+ DA D + L + + S D WH + +S E+ +P +N + Q++LI+++LR DR+ ++ F L + + P +N+ + E T P++ I+SPG DP+ L +L+ + R++ +++GQGQA I LL + G W+ L N HL SW+P L+K + L+ PH FRLW+++ PH F +LQ+S+K+T E P G+K N+ R Y +E F + LF+L +FH+I+ ER+ F+ GW Y F+ +D +L + + W + L +GG V + +D R+L++YI YF D ++ + FY +P S Y I+ L + P F N D +SQ + + L LQ + T+ SRE K+L + +K +P+ + T SP VV +++RYN KL+K + SL L K ++G +++ ++ + C+ P +W + + + + R L ++ + E WA + L L P FL A+ Q AR IS+D L + V SN+ K V + L++EG +D C ++ + L+ + + S M S P YY R V ID+ S D WI+ G AL +
Sbjct: 1043 LNIQFVMLDCSHLKFSLVQHCNEWQNKFTTLLKEM---AAGRLADLHSYLKDNAEKISHPPQTLEELGVSLQLMDTLQHDLPNLETQIPPIHEQFTILEKYEVPVPDTVLEMLESLNGEWLTFQQILLDSEQMLKKHKEKFKTGLIHAADDFKKKAHNLLEDFEFKGPFTSTV--GHTAALDQIAQMRAMLMAMRDEENNLRSNLGIFKIEQPVSKDLQILEKELDALQQVWEITRDWEES---WNQWKMGCFQT-LQTEAMESMAHGLFRRLTRLAKEY------KDRNWEIIETT---RSKIEQFKRTMPLISDLRNPALRERHWDQVKEEVQREFDQESESFTLEQIVKLGMD--QHVEKIAEISASATKELAIEVGLQNIAKTWDSTQLDIVPYKDKGHHRLRGTEE---VFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMVLTVQRQWMYLENIFLGEDIRKQLPNESALFDQVNNNWKAIMDRMNKDNNALRSTHYPGLLETLIEMNAILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLKIQKVGGSSSKWEAVGMFSGDGEYIDFLHPVLLEGPVESWLGDVERAMRMTLRDLLRNCRVALKKFLNKRDKWVK--DWAGQVVITASQIQWTADVTKCLMTAKERSDKKILKVSILNKYSEA---IRGNLTKIMR-LKIVALVTIEIHARDVLEKLYKSGLMDVSSFDWLSQLRFYWEKDVDDCIIRQTNTQFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQSGAWGCFDEFNRINIEVLSVVAQQILSILSALTANLTRFYFEGFEINLVWSCGIFITMNP---GYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGK-------KRRLQPDLSDEEV---------LLLSMRDMNIAKLTSVDVPLFNAIVQDLFPNIELPVIDYGKLRDTIEQEIREMGLQITPFTLTKVLQLYETKNSRHSTMIVGGTGSSKTTSWKILQASLTSLCRAGEPNYNIVREFPLNPKALSLGELYGEYDLNTNEWTDGILSSVMRVACADEKPDEKWILFDGPVDTLWIESMNSVMDDNKVLTLINGERIAMPEQVSLLFEVENLAVASPATVSRCGMVYTDYVDLGWKPYVQSWLEKRPKTEVEPLQRMFEKFINKILSFKKDNCNELVPVPEYSGIISLCKLYTVLATPENGVNPADAENYSFMVEMTFVFSMIWSVCASVDEDGRKKIDSYLREI-EGSFP--NKDTVYEYYVNPKMRTWTSFEEKLPKSWRYPPNAPFYKIMVP---TVDTVR-YNYLVSTLVAN-QNPVLLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESR---VEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRVKQSIKHIRDMFLMAAMGPPGGGRTVISPRLQSRFNIINMTFPTESQIIRIFGTMINQKLQDF---------EEEVKPIGNVVTEATLDVYNTVVQRFLPTPAKIHYLFNLRDISKVFQGMLRANKDFHDTKASITRLWI--HECFRVFSDRLVDTADMEAFMGILSDKLGTFFDLTFHHLCPNKRPPIFGD------FLKEPKVYEDLVDLT--VLKTAMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYNTFQIEVTKHYRKQEFRDDIKRLYRQAGVELQTTSFLFVDTQIADESFLEDINNILSSGEVPNLYKSDEFEEIQNHIIDQARAEQIPESSDSLFAYLIERVRNNLHIVLCLSPVGDPFRNWIRQYPALVNCTTINWFSEWPREALLEVAEKYI--IGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRR---YNYVTPTNYLELVSGYKKLLGEKRQELLDQANKLRTGLFKIDETREKVEVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVT-----ANSEKIAIEEVKCQALADN-------AQKDLEEAL--PALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN-EPTWAEAKRQLGEQNFIKSLINFDKDNISDKV---LKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAAMAQLQEKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLIAAAFLSYMGPFLTNYRDEIINQIWIRKIRELQVPCSPRFAIDNFLTNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQGQALKWIKNMEGNQGLKIIDLQMHDYLRVLEHAIQFGFPVLLQNVQEYLDPTLNPVLNKSVARIGGRMLIRIGDKEVEYNPNFRFYLTTKLSNPHYNPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLQTSKITATEVTEQLETSETTEINIDLAREAYRPCAQRASVLFFVLNDMGRIDPMYQFSLDAYIGLFILSIDKSHRSNKLEDRIEYLNDYHTYAVYRYTCRTLFERHKLLFSFHM--CAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCTSWLADAYWDNITELDKLTNFHGLMNSFEQYPRD--WHLWYTNSSPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIVSNLGSRFIEPPVLNMKSVMEDST-PRSPLVFILSPGVDPTSALLQLAEHTGMAHRFHALSLGQGQAPIAARLLREGVNQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSSPHPDFPISILQASIKMTTEPPKGLKANMTRLYQLMTEAQFTHCSKPAKYKKLLFALCFFHSILLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEET-PWDALKYLIAGVNYGGHVTDDWDRRLLTTYINDYFCD--LSLTTPFYRLSVLDTYYIPKDGSLASYKEYISMLPSMDPPEAFGQHPNADVASQITEARTLFETLLSLQP-QITPTRVGGQ--SREE-------KVLELAAD-VKQKIPEMIDYEGTRKLLALDPSPLNVVLLQEIQRYN--KLMKTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKVYPSQKPLASWTRDLAVRVEQFETWASRARPPVLFW----LSGFTFPTGFLTAVLQSAARQNNISVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRK--NSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSTDRASFVIGIDLRSGSMTSDHWIKRGTALLM 4452
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Mouse
Match: Dnah2 (dynein, axonemal, heavy chain 2 [Source:MGI Symbol;Acc:MGI:107731]) HSP 1 Score: 1229.93 bits (3181), Expect = 0.000e+0 Identity = 984/3544 (27.77%), Postives = 1719/3544 (48.50%), Query Frame = 3
Query: 2772 IKIDCITVNCAPIKMSVDTLI---QNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTV----SQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNL---------EKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEE--YQTGLQNLAKEDWLS--FRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGI-----YDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLR-MSNQSNYGINADKYPSQILCLSEMIHFTA---RC----EELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQT-------VKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDW-------IAKRNEFT--ISTSNVGTVY----NGLSNLKA----IKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQ--VTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIE----VYSQLKSKFTVDDYS-HYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQY--SRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSY----FLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISE--------------AKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRC-KDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKM-QLWMEK------TGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF--TGTFISDKSDRNITVPKWI-DA--DRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLK---PHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSE-DFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFY-----GKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSST-------DSP--VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNV--SAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYY------DILRDKIVTKIDIPCQSGQQDKWIQSGVALFL 12986
+ I + ++C+ +K S+ QN F LL + G + + +YL ++ + +S PQ ++E+ + D + +QI + +L DTV L +W F+ ++ + M+++ E KT ++ F++ + ++ P + G T A Q +E +++NL KD + + E + + EI +D +++ W+Q++ +QT LQ A E FR L +E+ K RN EI T + +I+ +K +P++ +R L + HW ++ + E+ TL I+ + +H E I E++ A E+ I ++ + +V Y D ++ + +E + + DNQ L ++K S + + F+ WE L+ + E ++ + +QR+W+YLE IF + LP E + F +V+ ++++IM +N++N L G+ L M L+ QK+L+ YLE KR +FPRFYF+ +DDLLEILGQS NP+ ++ HLKK F I V + + M S DGE ++ + VL+ VE+WLG++ M+ TL D L L+ N+ + + + Q++ + I +TA +C +E ++ + +KK+ V LN Y+ A + + T I+ LK+ +L+ +H D++++L V+ ++WL QLRFY + C+I+ + +F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC EG+D KSMGR++ GL + G+WGCFDEFNR+ VLS V+ QI I + + +N+ + IFIT+NP GY GR +LP+NLK +FRP+AM PD+ LIAE+IL +GF N K L +K+ +++L+ + L+ Q HYD+GLRAL ++L+ A K + Q + + E V ++ ++R ++KLT D F ++++D+FPNI++ I+Y L IE+ I+E + K+L++YE R +IVG +GS K+T WK+L+ +L + + V+ + +NPKA+ +L G D++T EW+DG+L+ R + + + WI+ DG +D WIES+NSV+DDN++LT+ +GERI V+ +FE +L+ ASPAT+SR GM++ K V SWL+K+ + + L + F K L + + E++ IS + TV NG++ A + F +I + +++E+ R+ ++ E+ + P NK V YY N K ++ + + KI+ P T D R +Y L ++ Q P +L GP G GK+ + Q L S Q V ++ SAQTT +V + + T VY P + +I ++ D+N+P D +G+ + ++ I Y +YD + + + + GR+ +S R S + ++++P++ Q+ I+ + L+ +VK + N + E VY+ + +F HYLF D+++ +LR + +++ L I +E R+F DRLV + + GIL + + + + + + +G P + L LT LK ++ L +Y S + ++LF+E +++ ++ RV+ +P G++LL G G GR++ + L S + + ++ + Y ++F++D+K + AGVE + L D Q + +LE IN++L+SGEVP LY ++E E I + D A SL Y +R+++ LHI+L + F + PA ++ W +W R+++L++ I I + G+Q + + +T ++ Y L+L + T +Y+ + Y ++ +K+ E+ + N ++ G+ KI E AK+ VAE + + E ++ +++ EAD+ K +T A K +E++ + +N A D E AL P +++A A+ + D+ EI++ PP + +++ V+++ G + +W + LG++ + + FD I+ + ++++ C + F P R S+AA L WV+A Y + P N L+ + + + ++ + +V + + +K +++ A +L + + + A LV L E RW + + L +L L L+AAA + YM + R E + Q+W+ K +F + FLT + +W +GL SD S EN +++ +G +IDP A W+KN ++ L+I++ Q ++ VLE +++FG +++Q V + L+P L P+L + G R ++++GDK ++YNP+F+ +L T+ P P+ A + VNF + GL+ QLL + ++ +P+LEE+K +L+ K +L ++E+ +L+ L ATG++L++ L+ +L +K ++ +++ LE S ++++D R+A+ P A+ S LFFV++D+ +I+ MY+FSL +++ LF +++ S S R L VY Y CR++F+ +L+F+ HM C + E+ F G + + + W+ DA D + L + + S D WH + +S E+ +P +N + Q++LI+++LR DR+ ++ F L + + P +N+ + E T P++ I+SPG DP+ L +L+ + R++ +++GQGQA I LL + G W+ L N HL SW+P L+K + L+ PH FRLW+++ PH F +LQ+S+K+T E P G+K N+ R Y +E F + LF+L +FH+I+ ER+ F+ GW Y F+ +D +L + + W + L +GG V + +D R+L++YI YF D ++ + FY +P S Y I+ L + P F N D +SQ + + L LQ + T+ SRE K+L + +K +P+ + T SP VV +++RYN KL+K + SL L K ++G +++ ++ + C+ P +W + + + + R L ++ + E WA + L L P FL A+ Q AR IS+D L + V SN+ K V + L++EG +D C ++ + L+ + + S M S P YY R V ID+ S D WI+ G AL +
Sbjct: 1043 LNIQFVMLDCSHLKFSLVQHCNEWQNKFTTLLKEM---AAGRLADLHSYLKDNAEKISHPPQTLEELGVSLQLMDTLQHDLPNLETQIPPIHEQFTILEKYEVPVPDTVLEMLESLNGEWLTFQQILLDSEQMLKKHKEKFKTGLIHAADDFKKKAHNLLEDFEFKGPFTSTV--GHTAALDQIAQMRAMLMAMRDEENNLRSNLGIFKIEQPVSKDLQILEKELDALQQVWEITRDWEES---WNQWKMGCFQT-LQTEAMESMAHGLFRRLTRLAKEY------KDRNWEIIETT---RSKIEQFKRTMPLISDLRNPALRERHWDQVKEEVQREFDQESESFTLEQIVKLGMD--QHVEKIAEISASATKELAIEVGLQNIAKTWDSTQLDIVPYKDKGHHRLRGTEE---VFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMVLTVQRQWMYLENIFLGEDIRKQLPNESALFDQVNNNWKAIMDRMNKDNNALRSTHYPGLLETLIEMNAILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLKIQKVGGSSSKWEAVGMFSGDGEYIDFLHPVLLEGPVESWLGDVERAMRMTLRDLLRNCRVALKKFLNKRDKWVK--DWAGQVVITASQIQWTADVTKCLMTAKERSDKKILKVMKKKQVSILNKYSEA---IRGNLTKIMR-LKIVALVTIEIHARDVLEKLYKSGLMDVSSFDWLSQLRFYWEKDVDDCIIRQTNTQFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQSGAWGCFDEFNRINIEVLSVVAQQILSILSALTANLTRFYFEGFEINLVWSCGIFITMNP---GYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGK-------KRRLQPDLSDEEV---------LLLSMRDMNIAKLTSVDVPLFNAIVQDLFPNIELPVIDYGKLRDTIEQEIREMGLQITPFTLTKVLQLYETKNSRHSTMIVGGTGSSKTTSWKILQASLTSLCRAGEPNYNIVREFPLNPKALSLGELYGEYDLNTNEWTDGILSSVMRVACADEKPDEKWILFDGPVDTLWIESMNSVMDDNKVLTLINGERIAMPEQVSLLFEVENLAVASPATVSRCGMVYTDYVDLGWKPYVQSWLEKRPKTEVEPLQRMFEKFINKILSFKKDNCNELVPVPEYSGIISLCKLYTVLATPENGVNPADAENYSFMVEMTFVFSMIWSVCASVDEDGRKKIDSYLREI-EGSFP--NKDTVYEYYVNPKMRTWTSFEEKLPKSWRYPPNAPFYKIMVP---TVDTVR-YNYLVSTLVAN-QNPVLLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESR---VEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRVKQSIKHIRDMFLMAAMGPPGGGRTVISPRLQSRFNIINMTFPTESQIIRIFGTMINQKLQDF---------EEEVKPIGNVVTEATLDVYNTVVQRFLPTPAKIHYLFNLRDISKVFQGMLRANKDFHDTKASITRLWI--HECFRVFSDRLVDTADMEAFMGILSDKLGTFFDLTFHHLCPNKRPPIFGD------FLKEPKVYEDLVDLT--VLKTAMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYNTFQIEVTKHYRKQEFRDDIKRLYRQAGVELQTTSFLFVDTQIADESFLEDINNILSSGEVPNLYKSDEFEEIQNHIIDQARAEQIPESSDSLFAYLIERVRNNLHIVLCLSPVGDPFRNWIRQYPALVNCTTINWFSEWPREALLEVAEKYI--IGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRR---YNYVTPTNYLELVSGYKKLLGEKRQELLDQANKLRTGLFKIDETREKVEVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVT-----ANSEKIAIEEVKCQALADN-------AQKDLEEAL--PALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN-EPTWAEAKRQLGEQNFIKSLINFDKDNISDKV---LKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAAMAQLQEKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLIAAAFLSYMGPFLTNYRDEIINQIWIRKIRELQVPCSPRFAIDNFLTNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQGQALKWIKNMEGNQGLKIIDLQMHDYLRVLEHAIQFGFPVLLQNVQEYLDPTLNPVLNKSVARIGGRMLIRIGDKEVEYNPNFRFYLTTKLSNPHYNPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLQTSKITATEVTEQLETSETTEINIDLAREAYRPCAQRASVLFFVLNDMGRIDPMYQFSLDAYIGLFILSIDKSHRSNKLEDRIEYLNDYHTYAVYRYTCRTLFERHKLLFSFHM--CAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCTSWLADAYWDNITELDKLTNFHGLMNSFEQYPRD--WHLWYTNSSPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIVSNLGSRFIEPPVLNMKSVMEDST-PRSPLVFILSPGVDPTSALLQLAEHTGMAHRFHALSLGQGQAPIAARLLREGVNQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSSPHPDFPISILQASIKMTTEPPKGLKANMTRLYQLMTEAQFTHCSKPAKYKKLLFALCFFHSILLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEET-PWDALKYLIAGVNYGGHVTDDWDRRLLTTYINDYFCD--LSLTTPFYRLSVLDTYYIPKDGSLASYKEYISMLPSMDPPEAFGQHPNADVASQITEARTLFETLLSLQP-QITPTRVGGQ--SREE-------KVLELAAD-VKQKIPEMIDYEGTRKLLALDPSPLNVVLLQEIQRYN--KLMKTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKVYPSQKPLASWTRDLAVRVEQFETWASRARPPVLFW----LSGFTFPTGFLTAVLQSAARQNNISVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRK--NSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSTDRASFVIGIDLRSGSMTSDHWIKRGTALLM 4458
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. UniProt/SwissProt
Match: sp|Q27802|DYHC2_TRIGR (Cytoplasmic dynein 2 heavy chain 1 OS=Tripneustes gratilla OX=7673 GN=DYH1B PE=2 SV=2) HSP 1 Score: 4734.09 bits (12278), Expect = 0.000e+0 Identity = 2344/4304 (54.46%), Postives = 3159/4304 (73.40%), Query Frame = 3
Query: 192 LDKFFDNLDNNVLVVKF----IDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKP-LSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKS--VGSQSKTKNVVQ--WNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNA----EITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSA---DSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSV-EVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQ-------GILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSD--RNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSG-----NFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
L+ F D+ + +VL K + K SN+++ +D + F K P +I+PDN+ S I+ ++ ++P +L + + ++ P+L+ D +PK+Q L+SEL GL S++RK S+ + + GI + DE W++ + + + R +SF + V+ E ++ + SL E+ +E ++D+W+ +P YP+ RM L+E+I + R IQ +L W D + VK++L I +C W+ C+KL +++WK+ H WN +S RL EIS+LRT+HEQ+ ++L E++E ++++ F F + PL YNPYTEP W+ AV ++ R I PAE I +L+ F+ P QLLR FQ+Y +L++R + ++ ERETLL QL ++ K +R+DF R+ + P KN + ++ IVW +QLEAK+ + + +L DL GF +F ++ + L+E+ NWRQ+QF+ W+ EM + D N + L M GRLME K+ L V+YS+RLV L+REVR L LGY ++ + A QKFY VILKQVA F+N+I QMIP Q+ MML +A+ FE+++K+ GS+ + VQ W NP+EL ++I KLQ A+ + ++NR LRK H+ +C+K+V+LM IDLLRQQ +WK+ L EIR I+ +E+Q + ++ WK H D QLYKALE+QY +GLEALNENLPEI+V+L YRQ LQF P EEI++KY++EMKKFI+LP F+G+ D+ G LI+P++IERNA+GF+ Y+ AE LF +L + FK W++LGS+DL++ ++ H +TD+E+NFKA+K +G+++EKLP+++K+ C+TV+ AP+K ++D IQ +FD+LL+SLR++I ++ ++ +L + ++ L+ PQ ++EI A HAE + +R D++E N LLRTVAGGG+D +QL W+KFELMMES Q+M++EQ+ VMK+N+ SR F+ ++ KF+ RW KP ++++SG ++CL AV+ +K+KK+E +E+ K +L DC+HF++E F++ ++ D DQ MW+ +EE+ GL L EDW+ FRS+ Y F++FLT W EKL++ E T MT+RL K+ID YK + P+LK++ + +Q+HW++++R+L MPR T+E +T IL A I+ +A+ +K+L +A+GEV+IREA+REL++WG GA F L EY DS ++ + LIK+W+D+++QVGDNQ LLQSLKDSPYY+ F DKA +WE +LADLDEYLQNLNQIQRKWVYLEPIFG+ ALPKE+ RFRRVD+DFRSIM DV R+NRVLSL SG++ L+T++DQLQRCQKALNE+LEEKRS+ PRFYFIGDDDLLEILGQS NP VI+SHLKKLF GI+ V+F++ +HI MKSL+GEVV L V IT EVE WLG+L EMK+TL L L+D + S+ S G++ KYPSQIL L+ I FT +CE + +N++ L EL ++L YT+A +S +A ++ V +LKLK+LILDT+H++D++ L +N S+ W W KQLR+Y + + +++MVDAEF YTYEYQGNA KLVHTPLTDKCYLTLTQGMHMG+GGNPYGPAGTGKTESVKALG LFGRQVLVFNCDEG+DVKSMGRIFIGLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQ +K K ++ LL+R +++D NS IFITLNPAGKGYGGRQKLPDNLK +FRPVAMSRPDN+ IAEVIL S+GFK+ K LGRKLVAIFNL++ELLTPQQHYDWGLRALKTVL+G NLL++ + Q VQ E KL+VQALRVNTLSKLT++DGI F++L+KDVFP +++K+IEY LA AI + KE N+V ++ Q KK LE+YEQLRQRMGVV+VGPSGSGKST W++LR ALN GQ VK Y MNPKA+PRTQLLGHID+DTREWSDGVLTYSARQVV+EPQEI SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIF+S E T++K LV SWL Q E ++ L+ +++D FY++L+W+ ++ +F + TS VG V NGLS+L+ + + F++ LI+GLG NL E +R FA V+ +T E+ P + + +L+ YF+E+ L TY+ + +ELS + + P+I T D+QR LD+F WL +D +QPFIL GP+GCGK ++L HCF +L+S Q+ T+HC+AQT+P H+LQKL Q C+++++NTGRVYRPK+ E L+LYLKD+NLPK DKWGT QL++FLQQV+TY GFYD LE+VGLDGVQIV SMN++ ++GR LSTRFTSIVR+CSI Y ++QL IY+AYL+PVL R + HP+WS SKV +LA +MI +Y Q++SKFT+DD+SHYLFTP DLTQWVL LLRYDL +S++T+ +LE++SYE+ R+F DRLV +AR R D IL T+ ++W+ ++ +LN ++VTWG+R ++G P GKSLG+L++ LK+ I + ++RE R+LDI +F EV D+VA++DRVLT+P GS+LLAG+SGVGRRT + LV+H H +L SP + R Y LKQFKNDLK+ +Q AGVEG +VLLLEDHQF++PQ+LELINSLL+SGE+PGLY+ EELEP+L ++D A+E G RG+L +Y+A RI LH++LIMD N +F +NCQSNPAF+K CSVQW+E WS++SM +IP +L+ + + ++ K +++G D + FL++H + V ST R Y+ F+ Y+ +Y +KK +E +Q H+Q G+ K++EAK +VAEL SKAA+QS LL EKQ EAD+ALKKI + M+ A E++ E+E L + EENV L KRK ID+ELA IEPQV+ A+ AV IKS LSEIRA+RAPPDVIRDILEGVL +MG DTSWVSM++FL KRG++EEI TFDAR+I ++ R E+LL + SFDP+NAKRAS+AAAPLAAWVKANVKYSYALEKI PLE EQNQLK+NLE A +++ L KG++DVD V Y++ F+K +AAKL++EL+ ETI++AE+L+ KLE E++RWN Q+ ELN EL L K+ AA + Y+ SSPED+RK+K+ W + GLE+FDMR+FL+TE EQL WK EGL SDELS+ENA++ILQ L PFLIDPS AT WLK H K+ +LE++NQQD+NFST LEL+VRFGKTLIIQE+D +EPVLYPLLR DLISQGPR VVQ+GDK+IDY+ DF+LF+ TRNP P++PPDA +I+S +NFTTT+AGL GQLLA T+QH KP+LE RKT LL++EE LKI+L+++EESLL+ LA A GNIL NK LL SLNKTKESS TI+QSL ESV+LQ SLD+ER A+LPLAE+GS+LFFVISDL+K+NNMYRFSL +FLRLF +AL + + MR LI L+ LVYEYVC+S+FK+DRLMFALH+ H P+ FK EWE F G ++D D ++ ++P W+D DR A+++ + P + L++ D+ LW F +SS+CE E P SL+ K+S FQ++L+IQA+RPDRLQSA++ F L +K L+ ++NL ++ + +T+ +EPILIIISPGADP+Q+LQE++ +VIG++ Y++VAMGQGQADI + LLH+CS+NG+WLCLKNLHLVT+WLPVLEKE+N+L PH++FRLW+TAE H F TILLQSSLKITYEAPPG+K NLLRSYD+W+ +FI + + RA ALF+LAWFHAI QERRNFIPQGWTKFYEFS++DLRAG +I+D++ + +Q++FI+GLFENAI+GGRVDNPFDMRVL SY+ +YFN ++ GS G +P ++ +D+ ++++ D + PSFF LP NI+RSSQRIIS QVI QL+IL+R KFD + W+ EL P+L+ WK LNQG N+I+ RS T P+ +F+QLERYN+++LV+FVHS+L +LSKV++G+ LLT EVQ L+ LL +TP W +WEGPE+P Y++ ++ + A++ W E ++++ LLS L+L ELFHPDTFLNALRQ TAR K SMD LKF CRW G+ AKY VKIG LH+EGC FDG ++E RDS S+ +P SV WV K+ PN+Y + ISLP+Y+ R+KIVT + +PC G+QD WIQ+G ALFL++
Sbjct: 37 LNTFLDDGNCSVLSAKLNSSGGNKKVYLSNKVDPSDTGEKVIAFFKLRPDVISPDNVQSSILTVSMMDSPAGALLHAVDKVFAPLLIEDEKYNRSFNPKLQSLLSELRAGLKSLVRKQDPSQGGPVKRGDNDFAGILTPSDEFQHWSEVAMSGRNQDAKERAEHFLSFFETVSREFDVLDTLSLEEAQELVETTQDAVDDVWKQGEFDP-YPEKRMAHLLEVIGSAFGRFIQRKLGEFDLWLDPFHKVKQALLSGIAICEKWVSSCEKLTEQFWKRDPMHPWN-GAKFTPEGLSQLSKRLQEISTLRTIHEQLIRLLSKGEQEEVRLKDVFSAFSGLNPLQYNPYTEPHWRAAVSQYERAINPAERRIAIKLRSQFRNVEGN--PNQLLREFQKYKELVSRESVRKEVVSERETLLGQLQVYLKSIRDDFNVRTSESSPPTGKNLPEVVNNIVWVRQLEAKVEQTSQVADTLLNDLSGFGRFRRDAGDLLDELRNWRQDQFDSWSSEMQAAISDP-NKPLSLQMTGRLMEFETKNNELIVSYSERLVTLMREVRQLQALGYPVAAKIQHTAAIAQKFYKHGVILKQVAHFHNSIAEQMIPSQRNMMLQSALAFERIIKNPRTGSKDAGQGKVQVTWENPKELEEYITKLQAAAEKLTTENRRLRKWHYTVCDKVVSLMSIDLLRQQPRWKEGLQEIRGIMASLESQGYKSQDMKSWKMHWDRQLYKALEHQYQMGLEALNENLPEIKVELTYRQQALQFRPPIEEIRAKYYREMKKFISLPYHFRGIGDT--GEPLIYPAIIERNASGFLNVYKMAEVLFSKLEKAKDIFKNWVVLGSVDLDKLLETHLHTVTDWERNFKALKARGRDSEKLPSQVKVYCVTVSTAPVKGTIDDHIQRLFDSLLSSLRRSITESVTEIEKFLKDGMEALATMPQTVEEIGNANAKHAELEAKKPEMRPMFDRAEAKNKLLRTVAGGGVDQFTQLHAHWEKFELMMESHQLMIKEQVNVMKSNVESRVDAFRAELEKFSARWNHAKPSPEVIESGDKESCLRAVELVKEKKVEFDEMQKTKNSLIFDCKHFELEEPFFSIANDLEVDFDQQTTMWTLYEEFSNGLSVLETEDWIVFRSKTYQFDDFLTTWTEKLKSGGPDVEHTIMTVRLSKDIDKYKTVSPLLKYLSSDIFTQEHWMDLYRMLKMPRSKTVERMTFGDILATADHIVANADGLKDLFNRAKGEVSIREALRELDVWGVGACFSLTEYSDSTDHQLMLIKDWKDLVTQVGDNQSLLQSLKDSPYYKGFADKATIWEQRLADLDEYLQNLNQIQRKWVYLEPIFGRGALPKEQGRFRRVDDDFRSIMMDVARDNRVLSLVGRSGLRTTLTTLLDQLQRCQKALNEFLEEKRSILPRFYFIGDDDLLEILGQSQNPAVIQSHLKKLFAGIHSVEFDQGCKHITAMKSLEGEVVPLLKAVEITPEVEIWLGDLAKEMKSTLRKLLVDCLKD-QQSSSSGVGVDPTKYPSQILGLAAQIQFTEQCETAIRDNSLQDLLIELEQQLEGYTSADISGAAGERNAAIHVLELKLKALILDTIHSLDVVQLLQKENVTSLDNWLWQKQLRYYLDNT-KTAIMRMVDAEFQYTYEYQGNAAKLVHTPLTDKCYLTLTQGMHMGMGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGVDVKSMGRIFIGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQAALKQKKPKVDLLDRTIDIDPNSGIFITLNPAGKGYGGRQKLPDNLKHVFRPVAMSRPDNEQIAEVILFSEGFKDGKSLGRKLVAIFNLAKELLTPQQHYDWGLRALKTVLRGCGNLLQI----ARQQAGQDRSKVQ----EPKLVVQALRVNTLSKLTFSDGIRFDALVKDVFPGVELKDIEYMTLADAIRQHCKEHNLVVMETQVKKALELYEQLRQRMGVVVVGPSGSGKSTTWQILRAALNNTGQVVKQYTMNPKAMPRTQLLGHIDMDTREWSDGVLTYSARQVVREPQEIHSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSCASPATISRMGMIFMSDEDTEIKDLVQSWLSHQAEESRNRLAAWIEDHFYRALEWVMRQGDFVVDTSLVGVVMNGLSHLRGAECISDFTIKLIRGLGANLPEATRMNFAKEVFHMTREQPP--DPRRILDTYFDERTGSLATYTMQDNDELSASDFNNPSSL--PVIRTPDVQRCLDFFNPWLEADNRQPFILVGPDGCGKGMVLRHCFAQLRSTQIATIHCNAQTSPTHLLQKLQQMCMVLSTNTGRVYRPKDCENLVLYLKDLNLPKPDKWGTCQLLAFLQQVLTYHGFYDDKLEWVGLDGVQIVASMNAAHTVGRHPLSTRFTSIVRICSIGYADREQLQGIYSAYLRPVLHRSLGNHPVWSSPSKVSMLAGSMISIYEQVRSKFTIDDHSHYLFTPRDLTQWVLGLLRYDLGGSSESTSEHVLEVLSYEARRLFCDRLVGEEARNRFDNILNGTLQADWNAGQILQNLNGHYYVTWGARTETSSGGSLPPAGKSLGRLSASDLKEVIKKAKKTFARENRELDIQIFHEVLDHVARVDRVLTQPRGSLLLAGRSGVGRRTAASLVAHCHRTELFSPNLSRAYGLKQFKNDLKTAMQQAGVEGNQVVLLLEDHQFIQPQFLELINSLLSSGEIPGLYSPEELEPLLAPIRDQASEEGFRGTLISYYASRILTNLHVVLIMDSKNASFAVNCQSNPAFYKSCSVQWMEGWSKESMKEIPRLLLRHHKGDTKDEGSKEDRKRHRKVSGGDEIIRNFLEIHKSSSVRHSTPRRYMTFLHTYLDVYRRKKQGVEEKQKHLQAGVAKLNEAKALVAELNSKAAKQSALLAEKQKEADEALKKIQTSMEKAGEQRREIEILKQQADEENVKLEKRKRVIDEELAEIEPQVQAAKSAVGSIKSESLSEIRAMRAPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVKEEISTFDARKINKDLREGTEQLLKKHASSFDPQNAKRASVAAAPLAAWVKANVKYSYALEKIEPLETEQNQLKKNLEKAVGRIEKLSKGLADVDHRVDEYKRRFQKLNEEAAKLKYELEKEQETIASAENLIGKLEGEYQRWNNQVSELNTELETLPKKAQCAAGFITYLTSSPEDERKQKLAEWSKLCGLERFDMRRFLSTESEQLTWKGEGLPSDELSVENAVMILQTNDMSIKSSLRPFLIDPSLRATEWLKTHLKEARLEVINQQDANFSTALELAVRFGKTLIIQEMDKIEPVLYPLLRADLISQGPRFVVQIGDKVIDYHEDFRLFMTTRNPNPEIPPDAASIISEINFTTTRAGLTGQLLAATIQHEKPELEVRKTELLKQEEDLKIQLAQLEESLLETLAKAEGNILENKALLESLNKTKESSQTITQSLVESVQLQESLDQERAAYLPLAENGSALFFVISDLAKLNNMYRFSLGAFLRLFSKALQGRMDGSSTEMRIQKLIKSLQMLVYEYVCQSLFKADRLMFALHLVHGMHPNHFKENEWEAFLGQIVADVRDSQQSGSMPSWVDQDRHKALASFMATFPSVGQSLSLTDNGLWGHFNRSSQCEHEFPTSLEKKISPFQQLLLIQAIRPDRLQSAMTFFAQRGLGMKELTTPTINLKRLCQ-DTVPSEPILIIISPGADPTQELQEVAAEVIGADHYHEVAMGQGQADIAMQLLHECSRNGEWLCLKNLHLVTAWLPVLEKEMNALSPHENFRLWLTAESHPKFPTILLQSSLKITYEAPPGIKKNLLRSYDSWTPEFIGRENNVVRAQALFALAWFHAICQERRNFIPQGWTKFYEFSMSDLRAGADIIDRLCHGKGKEVQFEFIYGLFENAIYGGRVDNPFDMRVLRSYLAQYFNKEMLGGSSARRSKKLPGGNSIPVSSYYKDFTELVSKFPDDDKPSFFGLPANIERSSQRIISVQVISQLKILRRSDEAAEKFDTEKWNTELGPILSLWKKLNQGSNLIQTKAQPPSDRSGTQGPIDSFIQLERYNALQLVQFVHSTLAALSKVIRGTSLLTSEVQALASNLLKQETPLSWQSKWEGPEDPVLYLKTIVSRTMAIQGWVEKAQRNNLLSDTLNLSELFHPDTFLNALRQQTARDSKTSMDSLKFACRWSGNISGAKYQVKIGGLHLEGCTFDGQRLSENQRDSPSVCSVPACSVAWVLKDTPNTYHASESISLPVYFTEQREKIVTHLVLPC-GGEQDHWIQTGAALFLQN 4317
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. UniProt/SwissProt
Match: sp|Q8NCM8|DYHC2_HUMAN (Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4) HSP 1 Score: 4532.63 bits (11755), Expect = 0.000e+0 Identity = 2338/4334 (53.95%), Postives = 3110/4334 (71.76%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHFPNQNSKFVNE---ECLD--KFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVP-------PTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAE-ITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLS--ADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLL-EMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVS-LLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVV------NGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RK IF T+++F + + CL+ F D+ + +L V+ D FSN + D LVF K P +IT +N++ I+V+++ E+PISSLY ++ ++ P+LL D DPK+Q L+SELE GLG ++R+ + +K + E GI + DE FW + + ++ R N + + E + S SL E +E +++D+W+ +T + +YP+SRM L++II R +Q +L L WED Y LVKESL I +C W+ +C+ L + W++Y+PH W + + + RL E+ ++RT+HE+ LP E + + F+ F + P+ YNPYTEP+WK AV ++ + I PAE I +LK E + PQQLL+ F +Y +L+ RP IS L+ ERETLLA+LV K R DF +R R +P KN S+ ++ IVW +QLE K+++ + I +L DL GF F + K+ L+++ + QEQF+ W++++ L DS + G+ ++ R+MEL DGLL V+YSDRLV L+REVR LS LG+ I + A+ QKF +A+ILKQVA FYN+I+ QMI Q+ MML +A+ FE+++K+ + S K+ + W+NP+EL +I KLQ A+ + ++NR LRK H CEK+V LM IDLLRQQQ+WKD L E+R L +E Q + WK+H +HQLYKALE+QY +GLEALNENLPEI +DL Y+QGRLQF P FEEI++KY++EMK+FI +PNQFKG+ ++ G++ IF +I+RNA+GF+ + KAE LF+RLSA L++ KEWI++G +D+E V++H + D+EKNFKA+K KGKE E+LP+ +K+DC+ +NC P+K +D LIQ +FD L+ SL+K+I+ + +D ++T ++++L+ PQ+++EI +A L +++ + + I ++E N LLRTVAGGG++T+S L+ KWDKFELMMES Q+M+++QIEVMK N+ SR + + Q++ KF RW LKPG D++++G + + IK+KK+E ++L + + L DC HF++E F+L I KDI+ +W+ +EE+Q G Q +A EDW++FR++ YLFEEFL W ++LR E + MT++LQ E+D YK +IPILK++RGE LS DHWL++FRLL +PRG +LE L +L A I+ A +K+LN +AQGEVTIREA+REL+LWG GAVF L++Y DSQ+ ++ LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK ++WE KLA+LDEYLQNLN IQRKWVYLEPIFG+ ALPKE++RF RVDEDFRSIM+D+ ++NRV +L + +G++N L T++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQSTNP VI+SHLKKLF GI V F++ +HI MKSL+GEVV +N+V +++ VE WL +L EMK TL L + R S + ++ +PSQILCL+E I FT E + ++++ ++ +LV KL YTN S ++ + +LKLK+LILD +HNID++ QL + +W W KQLRFY KS D C +QMVD+EF YTYEYQGNA KLV+TPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEE+VLSAVSMQIQ IQD +KN LL + V V+ NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMS PDN+LIAEVIL S+GFK+AK L RKLVAIFNLSRELLTPQQHYDWGLRALKTVL+G+ NLL +++KS N E+ ++VQALR+NT+SK T+ D F++LIKDVFP I++KE+EYD L++A+++V +E N + Q KK LE+YEQL QRMGVVIVGPSG+GKST+W++LR AL K G+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQ++ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+ SL+ SWL+ Q ++ L ++ D+F K+L W+ K+N++ + TS VGTV NGLS+L ++ F + LI+GLGGNLN SR F V+ E P+ +K ++ Y++ + RL TY + E+L+ D + + P+I T D+QR LDYFK WL+SDT+QPFIL GPEGCGK ++L + F +L+S Q+ T+HCSAQTT H+LQKL+Q C++I++NTGRVYRPK+ ERL+LYLKDINLPKLDKWGTS L++FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ +GR L+TRFTSIVRLCSI YP ++QL IY AYL+PVL + + H IW +SK+ LLA +M++VY Q+++KFTVDDYSHY FTP LTQWVL L RYDL S N + +LEIV+YE+ R+F+D++V + D IL + +W ++ D+++D ++VTWG+R A A P GK LGKL S LKD I +GL+ Y R+ ++LDI+LF EV + ++++DRVL+ PGGS+LLAG+SGVGRRT + LVSHMH L SPK+ RGYELKQFKNDLK LQ AG+E + +VLLLED+QF+ P +LE+INSLL+SGEVPGLYT EELEP+L+ LKD A++ G G + NYF RI+ LHI+LIMD +N NF+INC+SNPA K C V W+E WS SM KIP ML ++ E + + K D L S+ L +H++C +T Y+ F+ +Y I KK E+ RQ+H+Q G+ K++EAK +V EL KA EQS LL KQ EAD AL+ IT MQ A+E+K E+E+L + EE V + +RK IDDEL ++P V +A+ AV +IK LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+I TFDAR I++E R VEELL + K SFDPKNAKRAS AAAPLAAWVKAN++YS+ LE+I PLE EQ L+ NL+ E + + LE+ ++ V + V+ ++ F+ T++AAKLE E+ A ETI AAE L+ +L+ E +RWN Q+VE+ EL+ L ++ LAAA + Y+ ++PE RK ++ W + GLEKFD+R+FL TE EQL WK EGL SD+LS+ENALVILQ + PFLIDPSS AT WLK H KD +LE++NQQDSNF T LEL+VRFGKTLIIQE+DG+EPVLYPLLR DL++QGPR VVQ+GDK+IDYN +F+LFL+TRNP P +PPDA +IV+ VNFTTT++GL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+K+EESLL+ LA + GNIL NKDL+ SLN+TK SS I +SL+ES KLQ+SLD+ERDA+LPLAE S ++F+ISDLSKINNMYRFSL +FLRLFQRAL + S ++ R SLI+ L+ +VYEY+CR +FK+D+LMFALH P+LF+ EW+ FTG + D K+D + P WID +R+ A++ L A+P L+ L +D LW + +S CE+E P L K+SLFQ+IL++QALRPDRLQSA++ F C L LK +SP +NL ++Y+ ET+ EPILIIISPGADPSQ+LQEL+ E Y+QVAMGQGQAD+ + +L +C++NGDWLCLKNLHLV SWLPVLEKELN+L+P FRLW+TAE H F+ ILLQSSLKITYE+PPG+K NL+R+Y++W+ + ISK + RA+ALFSLAWFHA QERRN+IPQGWTKFYEFS++DLRAG I+D++ + +++QW+F+HGL ENAI+GGR+DN FD+RVL SY+K++FN SV+ N F + LP + S DY A+I ++ + + PSFF LP NI RSSQR+ISSQVI QLRIL R G+KFD++IWS EL+PVLN WK LNQ N+I +P R SP+++F+ LE++N+I+LV+ VH SL +LSKV++G+ LL+ EVQ L+ LL + P W +WEGPE+P Y+R L+ +A A++ W + +EK LLS LDL ELFHPDTFLNALRQ TAR + S+D LKFV W G AK +KI L +EGC FDG ++E DS S+ + P +GW+ ++ YS D+ ISLP+Y RD++VT ID+PC G QD+WIQ G ALFLK+
Sbjct: 7 DVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGISFSNTIEFGDTKDKVLVFFKLRPEVITDENLHDNILVSSMLESPISSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRRSDTNLTKLKFKEDDTRGILTPSDEFQFWIEQAHRGNKQISKERANYFKELFETIAREFYNLDSLSLLEVVDLVETTQDVVDDVWR-QTEHDHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNHLTGQVWQRYVPHPWKNEKYFPET-LDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTRVFEPFTGLNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDS--PQQLLQAFLKYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCR--GIPGDASGPLSGKNLSEVVNSIVWVRQLELKVDDTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDIQSGLSDSRS-GLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDLLRQQQRWKDGLQELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALNENLPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEA--GDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGA---VDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKS-DHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNAN-----------ESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQNDYVVETSLVGTVMNGLSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP--MDTYYDSTRGRLATYVLKKPEDLTADDFSNG--LTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLL-IHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYK-ETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGA-KDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQG--SPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVYTSAERDRVVTNIDVPC-GGNQDQWIQCGAALFLKN 4306
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. UniProt/SwissProt
Match: sp|Q9JJ79|DYHC2_RAT (Cytoplasmic dynein 2 heavy chain 1 OS=Rattus norvegicus OX=10116 GN=Dync2h1 PE=1 SV=1) HSP 1 Score: 4517.22 bits (11715), Expect = 0.000e+0 Identity = 2333/4338 (53.78%), Postives = 3099/4338 (71.44%), Query Frame = 3
Query: 105 IEDQRKDTIFLITKSHF---PN--QNSKFVNEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVP-------PTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAE-ITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLS--ADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLL-EMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVS-LLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVV------NGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNII--KASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
+ D RK +F T+++F P + N ++ F D+ + +L V+ D FSN ++ D LVF K P +IT N+++ I+V+++ E+PI+SLY ++ ++ P+LL D DPK+Q L+SELE GLG ++RK + K + E GI + DE FW + S ++ R + + + E + S SL E +E +++D+W+ + + +YP+SRM L+++I R +Q +L L WED Y LVKE+L I +C W+ +C L + W++Y+PH W ++ + + RL E+ ++RT+HE++ LP E + + F+ F + P+ YNPYTEP+WK AV ++ + I PAE I +LK E + PQQLL+ F +Y +L+ RP IS L+ ERETLLA+L K R DF +R R +P KN S+ ++ IVW +QLE K+++ + I +L DL GF F + ++ L++ + QEQF+ W++E+ L DS + G+ ++ R+MEL DG L V+YSDRLV L+REVR LS LG+ I + A+ QKF +A+ILKQVA FYN+I+ QMI Q+ MML +A+ FE+++K+ + S K+ + W+NP+EL +I KLQ A+ + ++NR LRK H CEK+V LM IDLLRQQQ+WKD L E+R L + Q P + W++H +HQLYKALE+QY +GLEALNENLPEI VDL Y+QGRLQF P FEEI++KY++EMK+FI +PNQFKG+ + G++ IF +I+RNA+GF+ Y KAE LF+RLSA L++ KEW+++G +D+E V+++ + D+EKNFKA+K KGKE E+LP+ +K+DC+ +NC+P+K +D LIQ +FD L+ SL+K+I+ I +D ++T ++K+L+ PQ+++EI + L ++ R I ++E N LLRTVAGGG++TVS L+ KWDKFELMMES Q+M+++QIEVMK N+ SR + + Q++ KF RW LKPG DI+++G + + IK+KK+E ++L +I+ L DC HF +E F+L I KDI+ +W+ +EE+Q GLQ +AKEDW+++R++ Y+FEEFL W E+LR E + MT++LQ E+D YK IIPILK++RGE LS DHWL++FRLL +PRG +LE L +L A I+ A +K+LN +AQGEVTIREA+REL+LWG GAVF L++Y DSQN +I LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK ++WE KLA LDEYLQNLN IQRKWVYLEPIFG+ ALPKE++RF +VDEDFRSIM D+ +++RV +L + +G++N L T++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQSTNP VI+SHLKKLF GI V F+++ +HI M+SL+GEVV +++VL+++ VE WL +L EMK TL L + R S + I+ +PSQILCL+E I FT E+ + ++++ ++ +L KL YT+ S +S + +LKLK+LILD +HNIDI+ QL + +W W KQ+RFY KS D C +QMVD+E YTYEYQGNAPKLV+TPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQD +KN LL + V V+ NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVIL S+GFK+AKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVL+G+ NLL ++ KS K N E ++VQALR+NT+SK T+AD F++LIKDVFP ID KE+EY+ L+SA+++V +E N + Q KK LE+YEQLRQR GVVIVGPSG+GKST+W++LR AL KIG+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQ++ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+ SL+ SWL+ Q + L ++ D+F K+L W+ K+N++ + TS VGTV NGLS+L K F + LI+GLGGNLN SR F V+ E P+ ++ ++ YF+ + +L +Y + E L+ D S + P+I T D+QR LDYFK WL+S+T+QPFIL GPEGCGK ++L + F +L+S ++ T+HCSAQTT H+LQKL+Q C++I++NTGRVYRPK+ ERL+LYLKDINLPKLDKWGTS L++FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ +GR L+TRFTSIVRLC++ YP ++QL IY AYL+ VL + + H IW +SK+ LLA +M++VY Q+++KFTVDDYSHY FTP LTQWVL L RYDL S N + +LE+V+YE+ R+F+D++V D IL + + +W ++ D++ D ++VTWG++ A P GK LGKL+S LKD I +GL+ Y R+ ++LDI+LF+EV + ++++DRVL+ PGGS+LLAG+SGVGRRT + LVSHMH L SPK+ RGYE KQF+ DLK L AG+E + +VLLLED+QF+ P +LE+INSLL+SGEVPGLYT EELEP+L+ LKD A++ G G + NYF RI+ LHI+LIMD +NLNF+INC+SNPA K C V W+E WS SM KIP ML ++ EE + + K K+ + D + S+ L +H++C +T Y+ F+++Y I K+ E+ RQ+H+Q G+ K++EAK +V EL KA EQS LL KQ EAD AL++IT MQ A+E+K E+E+L + EE V + +RK+ IDDEL ++P V +A+ AV +I+ LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+I TFDAR I +E R VEELL + K SFDPKNAKRAS AAAPLAAWVKANV+YS+ LE+I PLE EQ+ L+ NL+ E + + LE ++ V + V+ ++ F+ T++AAKLE E+ A ETI AAE L+ +L+ E RWN Q+ E+ EL+ L ++ LAAA + Y+ ++PE RK ++ W + GLEKFD+R+FL TE EQL WK EGL SD+LS+ENALVILQ + PFLIDPSS AT WLK H KD LE++NQQDSNF T LEL+VRFGKTLIIQE+DG+EPVLYPLLR DL++QGPR VVQ+GDK+IDYN DF+LFL+TRNP P +PPDA +IV+ VNFTTT++GL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+++EESLL+ LA + GNIL NKDL+ SLN+TK SS I SL+ES KLQ+SLD ERDA+LPLAE S ++F+ISDLSKINNMYRFSL SFLRLFQRAL + S + R L+ L+ +VYEY+CR +FK+D+LMFALH P+ F+ EW+ FTG + D K+D + P WID +R+ A++ L ++P L+ L +D LW + S CE+E P L K+SLFQ++L++QALRPDRLQSA++ F C L LK LSP +NL ++Y+ ET+ EPILIIISPGADPSQ+LQEL+ SERY+QVAMGQGQAD+ + +L +C++NGDWLCLKNLHLV SWLPVLEKELN+L+P + FRLW+TAE H F+ ILLQSSLKITYE+PPG+K NL+R+Y++W+ + ISK + RA+ALFSLAWFHA QERRNFIPQGWTKFYEFS++DLRAG ++D++ S +++QW+F+HGL EN+I+GGR+DN FD+RVL SY+K++FN S++ N F I LP + S DY A+I +L + + PSFF LP NI RSSQR+ SSQVI QLRIL R G KFD++IWS EL+PVLN WK LNQ N+I K S P+ + SP+++F+ LE++N+I+LV+ VH SL +LSKV++G+ LL+ EVQ L+ LL + P W +WEGPE+P Y+R L+ + A++ W E +EK LL+ LDL ELFHPDTFLNALRQ TAR S+D LKFV W G AK +KI L +EGC FDG+ ++E DS S+ + P +GW + YS D+ ISLP+Y RD +VT ID+PC G QD+WIQ G ALFLK+
Sbjct: 5 LSDVRKLFLFTTTQNYFGLRPELWDQTPLSNCPEVNNFLDDGNQMLLRVQRSDAGLAFSNTIDFDDTKDKVLVFFKLRPEVITDGNLHTNILVSSMLESPINSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGVVLRKSDTNLPKLKLKEDDTRGILTPSDEFQFWIEQAHRGSKQISKERASYFKELFETIAREFYNLDSLSLLEVVDLVETTRDVVDDVWR-QAEHDHYPESRMLHLLDVIGGSFGRFVQKKLGSLKLWEDPYYLVKENLKAGISICEQWVIVCSHLTGQVWQRYVPHPWKSEKYFPET-LDRLGKRLEEVLAIRTIHEKLLYFLPASEERIVCLSRVFEPFTGVNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDS--PQQLLQAFLKYKELVKRPTISKELMLERETLLARLGDSAKDFRLDFENRCR--GIPGDASGPLSGKNLSEVVNNIVWVRQLELKVDDTIKIAEALLSDLSGFRSFHRSAEDLLDQFKLYEQEQFDDWSREVQSGLSDSRS-GLCIEANSRIMELDPNDGALKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANVAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRRLRKWHITFCEKVVILMNIDLLRQQQRWKDGLQELRTGLASVAAQGFQPSDMRAWRQHWNHQLYKALEHQYQMGLEALNENLPEINVDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGGA--GDESIFSVMIDRNASGFLTIYSKAEDLFRRLSAVLHQHKEWVVIGQVDMEALVEKNLSTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCSPVKTVIDDLIQKLFDLLVLSLKKSIQTHIHEIDTFVTEAMKVLTVIPQSVEEIGDTNLQYSNLQDRRPEILPLFQEAEDKNRLLRTVAGGGVETVSNLRAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELDKFKARWDQLKPGDDIIETGQQNTMDQSAKSIKEKKIEFDDLEVIRKKLVDDCHHFGLEESNFSLAYSISKDIESCAQIWALYEEFQQGLQEMAKEDWITYRTKIYIFEEFLINWHERLRKVEEHSVMTVKLQSEVDRYKIIIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVEKASDLKDLNSRAQGEVTIREALRELDLWGVGAVFSLIDYEDSQNRTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAQLDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNKVDEDFRSIMMDIRKDSRVTTLTTHAGIRNTLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEESKHITAMRSLEGEVVPFKSKVLLSNNVEAWLNDLALEMKQTLKQLLKECVTAGRSSQGA---IDPSLFPSQILCLAEQIKFTEDVEDAIRDHSLHQIEAQLAAKLERYTSVDTSSEDPGNSESGILELKLKTLILDIIHNIDIVKQLNQAQVHTTDDWAWKKQVRFYMKS-DHTCYVQMVDSELQYTYEYQGNAPKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRSVCELLGKEVEVNANSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILYSEGFKDAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLKKSGTKQDVN-----------ENHIVVQALRLNTMSKFTFADCTRFDALIKDVFPGIDFKEVEYNELSSALKQVFEEANYEVIPNQMKKALELYEQLRQRTGVVIVGPSGAGKSTLWRMLRAALCKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPVEYRSNLENWIGDYFSKALQWVLKQNDYVVETSLVGTVMNGLSHLHGCKYHDQFIINLIRGLGGNLNMKSRLEFTKEVFNWARETPPDSHRP--MDTYFDCDRGQLASYVLKKPESLTADDFSSGHSL--PVIQTPDMQRGLDYFKPWLSSETKQPFILVGPEGCGKGMLLRYAFSQLRSTEIATIHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCAVDYPEREQLQTIYGAYLEAVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEVVAYEARRLFRDKIVGVKELHLFDNILTSVLQGDWGSDILDNMADSFYVTWGAQHISGAKIAPGQPLPPHGKPLGKLSSADLKDVIKKGLIHYGRDNQNLDILLFQEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTVTSLVSHMHGAVLFSPKISRGYEPKQFRTDLKHVLHLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANLNFIINCESNPALHKKCRVLWMEGWSDSSMKKIPEMLFSEADIEEKYEKKRKDEKKKSSVD-PDFIKSFLL-IHESCKAYGATPSRYMTFLRVYSAISSSKRKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSILLRIKQDEADSALQEITVSMQDASEQKTELERLKHRIAEEVVKIEERKSKIDDELKEVQPLVNEAKLAVGNIRPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNIPKEIRESVEELLFKNKASFDPKNAKRASTAAAPLAAWVKANVQYSHVLERIQPLETEQSGLELNLKKTEDRKRKLEDLLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLISQLDREHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKAAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSHLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEDFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLARLEESLLETLATSQGNILENKDLIESLNQTKASSALIQDSLKESYKLQISLDRERDAYLPLAESASKMYFIISDLSKINNMYRFSLASFLRLFQRALQNKQDSESTEQRIQCLVNSLKHMVYEYICRCLFKADQLMFALHFVRGMHPEFFQENEWDTFTGVVVGDMLRKADSQQRIRDQLPSWIDQERSWAVATLKISLPGLYQTLCFEDGTLWRTYYHHSMCEQEFPSILAKKVSLFQQVLVVQALRPDRLQSAMALFACKALGLKELSPLPLNLKRLYK-ETLEIEPILIIISPGADPSQELQELANAERSSERYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKESFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNIHRAHALFSLAWFHAACQERRNFIPQGWTKFYEFSLSDLRAGYHVIDRLFDGS-KDVQWEFVHGLLENSIYGGRIDNYFDLRVLQSYLKQFFNSSIIDVLNQRNKKSIFPYSISLPDSCSILDYRAVIEKLPEDDKPSFFGLPANIARSSQRMTSSQVISQLRILGRSVTAGCKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVSPPNDRQ----GSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLTWQSKWEGPEDPLQYLRGLVARTLAIQNWVEKAEKQALLADTLDLSELFHPDTFLNALRQETARATGCSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGSRLSENQHDSPSVSSVLPCYMGWTPQGSYGPYSPDECISLPVYTSAERDCVVTNIDVPC-GGNQDQWIQCGAALFLKN 4305
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. UniProt/SwissProt
Match: sp|Q45VK7|DYHC2_MOUSE (Cytoplasmic dynein 2 heavy chain 1 OS=Mus musculus OX=10090 GN=Dync2h1 PE=1 SV=1) HSP 1 Score: 4514.52 bits (11708), Expect = 0.000e+0 Identity = 2339/4344 (53.84%), Postives = 3103/4344 (71.43%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHF----------PNQNSKFVNEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPT-----KNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRN-AEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLS--ADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVS-LLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX----XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKI------PREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD---KSDRNITV----PKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVV------NGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNII--KASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RK +F T+++F P N VN F D+ + +L V+ + FSN ++ D LVF K P +IT N+++ I+V+++ E+PI+SLY ++ ++ P+LL D DPK+Q L+SELE GLG ++RK + K + E GI + DE FW + S ++ R + + ++ E + S SL E +E +++D+W+ +T + +YP+SRM L+++I R +Q +L L WED Y LVKE+L I +C W+ +C L + W++Y+PH W + + + RL E+ ++RT+HE++ LP E + + F+ F + P+ YNPYTEP+WK AV ++ + I PAE I +LK E + PQQLL+ F +Y +L+ RP IS L+ ERETLLA+L K R DF +R R P+ KN S+ ++ IVW +QLE K+++ + I +L DL GF F + ++ L++ + QEQF+ W++E+ L DS + G+ ++ R+MEL DG L V+YSDRLV L+REVR LS LG+ I + A+ QKF +A+ILKQVA FYN+I+ QMI Q+ MML +A+ FE+++K+ + S K+ + W+NP+EL +I KLQ A+ + ++NR LRK H CEK+V LM IDLLRQQQ+WKD L E+R L + Q + W++H +HQLYKALE+QY +GLEALNENLPEI VDL Y+QGRLQF P FEEI++KY++EMK+FI +PNQFKG+ ++ G++ IF +I+RNA+GF+ Y KAE LF+RLSA L++ KEW+++G +D+E V+++ + D+EKNFKA+K KGKE E+LP+ +K+DC+ +NC+P+K +D LIQ +FD L+ SL+K+I+ I +D ++T ++K+L+ PQ+++EI + + ++ R I ++E N LLRTVAGGG++TVS L+ KWDKFELMMES Q+M+++QIEVMK N+ SR + + Q++ KF RW LKPG DI+++G + + IK+KK+E ++L +I+ L DC HF +E F+L I KDI+ +W+ +EE+Q GLQ++AKEDW+++R++ YLFEEFL W E+LR E + MT++LQ E+D YK IIPILK++RGE LS DHWL++FRLL +PRG +LE L +L A I+ A +K+LN +AQGEVTIREA+REL+LWG GAVF L++Y DSQN++I LIK+W+DI++QVGDN+CLLQSLKDSPYY+ F+DK ++WE KLA LDEYLQNLN IQRKWVYLEPIFG+ ALPKE++RF +VDEDFRSIM D+ +++RV +L + +G++N L T++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQSTNP VI+SHLKKLF GI V F+++ +HI MKSL+GEVV +++VL+++ VE WL +L EMK TL L + R S + I+ +PSQILCL+E I FT E + ++++ ++ +LV KL YT+ S +S + +LKLK+LILD +HNIDI+ QL + +W W KQ+RFY KS D C +QMVD+E YTYEYQGNAPKLV+TPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG L GRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQD +KN LL + V ++ NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVIL S+GFK+AKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVL+G+ NLL K N T ++V E ++VQALR+NT+SK T+AD F++LIKDVFP ID KE+EYD L+SA+++V +E N + Q KK LE+YEQLRQR GVVIVGPSG+GKST+W++LR AL KIG+ VK Y MNPKA+PR QLLGHID+DTREWSDGVLT SARQVV+EPQ++ SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+ SL+ SWL+ Q + L ++ D+F K+L W+ K+N++ + TS VGTV NGLS+L K F + LI+GLGGNLN SR F V+ E P+ ++ ++ Y++ + +L +Y + E L+ D S+ IL P+I T D+QR LDYFK WL+SDT+QPFIL GPEGCGK ++L + F +L+S ++ T+HCSAQTT H+LQKL+Q C++I++NTGRVYRPK+ ERL+LYLKDINLPKLDKWGTS L++FLQQV+TY+GFYD NLE+VGL+ +QIV SM++ +GR L+TRFTSIVRLC+I YP ++QL IY AYL+ VL + + H IW +SK+ LLA +M++VY Q+++KFTVD+YSHY FTP LTQWVL L RYDL S N + +LEIV+YE+ R+F+D++V D IL + + +W ++ D++ D ++VTWG+ P GK LGKLTS LKD I +GL+ Y R+ ++LDI+LF+EV + ++++DRVL+ PGGS+LLAG+SGVGRRT + LVSHMH L SPK+ RGYE KQF+NDLK LQ AG+E + +VLLLED+QF+ P +LE+INSLLASGEVPGLYT EELEP+L+ LKD A++ G G + NYF RI+ LHI+LIMD +NLNF++NC+SNPA K C V W+E WS SM KIP ML ++ ++ + +NS P D + S+ L +H++C +T Y+ F+ +Y I KK E+ RQ+H+Q G+ K++EAK +V EL KA EQS LL KQ EAD AL++IT MQ A+E+K E+E+L + EE V + +RK+ IDDEL ++P V +A+ AV +I+ LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+I TFDAR I +E R VEELL + K SFDPKNAKRAS AAAPLAAWVKANV+YS+ LE+I PLE EQ+ L+ NL+ E + + LE ++ V + V+ ++ F+ T++AAKLE E+ A ETI AAE L+ +L+ E RWN Q+ E+ EL+ L ++ LAAA + Y+ ++PE RK ++ W + GLEKFD+R+FL TE EQL WK EGL SD+LS+ENALVILQ + PFLIDPSS AT WLK H KD LE++NQQDSNF T LEL+VRFGKTLIIQE+DG+EPVLYPLLR DL++QGPR VVQ+GDK+IDYN DF+LFL+TRNP P +PPDA +IV+ VNFTTT++GL+GQLLALT+QH KP LEE+KT LLQ+EE KI+L+++EESLL+ LA + GNIL NKDL+ SLN+TK SS I SL+ES KLQ+SLD+ERDA+LPLAE S ++F+ISDLSKINNMYRFSL SFLRLFQRAL + S ++ R L+ L+ +VYEY+CR +FK+D+LMFALH P+LF+ EW+ FTG + D K+D + P WID +R+ A++ L ++P L+ L ++D W + S CE+E P L K+SLFQ++L++QALRPDRLQSA++ F C L LK LSP +NL ++Y+ ET+ EPILIIISPGADPSQ+LQEL++ SE Y+QVAMGQGQAD+ + +L +C++NGDWLCLKNLHLV SWLPVLEKELN+L+P FRLW+TAE H F+ ILLQSSLKITYE+PPG+K NL+R+Y++W+ + ISK + RA+ALFSLAWFHA QERRN+IPQGWTKFYEFS++DLRAG ++D++ +++QW+F+HGL EN+I+GGRVDN FD+RVL SY+K++FN S++ N F I LP++ S DY A+I +L + + PSFF LP NI RSSQR+ISSQVI QLRIL R G KFD++IWS EL+PVLN WK LNQ N+I K S P+ + SP+++F+ LE++N+I+LV+ VH SL +LSKV++G+ LL+ EVQ L+ LL + P W +WEGPE+P Y+R L+ + A++ W E +EK LL+ LDL ELFHPDTFLNALRQ TAR S+D LKFV W G AK +KI L +EGC FDG ++E DS S+ + P +GW + YS D+ ISLP+Y R+++VT ID+PC G QD+WIQ G ALFLK+
Sbjct: 7 DVRKLFLFTTTQNYFGLRPELWDQPPLSNCPEVN-----NFLDDGNQMLLRVQRSEAGLAFSNTIDFDDAKDKVLVFFKLRPEVITDGNLHNNILVSSMLESPINSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRKSDTNLPKLKLKEDDTRGILTPSDEFQFWIEQAHRGSKQISKERASYFKELFETISREFYNLDSLSLLEVVDLVETTRDVVDDVWR-QTEHDHYPESRMLHLLDVIGGSFGRFVQKKLGSLKLWEDPYYLVKENLKAGISICEQWVIVCSHLTGQVWQRYVPHPWKSGKYFPET-LDKLGKRLEEVLAIRTIHEKLLYFLPASEERIVCLSRVFEPFTGVNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDS--PQQLLQAFLKYKELVKRPTISKELMLERETLLARLGDSAKDFRLDFENRCRGIPGDPSGPLSGKNLSEVVNNIVWVRQLELKVDDTIKIAEALLSDLSGFRSFHRSAEDLLDQFKLYEQEQFDDWSREVQSGLSDSRS-GLCIEANSRIMELDPNDGALKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANVAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRRLRKWHTTFCEKVVILMNIDLLRQQQRWKDGLQELRTGLATVAAQGFQASDMRAWRQHWNHQLYKALEHQYQVGLEALNENLPEINVDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEA--GDESIFSVMIDRNASGFLTIYSKAEDLFRRLSAVLHQHKEWVVIGQVDMEALVEKNLSTVHDWEKNFKALKIKGKEVERLPSAVKVDCLNINCSPVKTVIDDLIQKLFDLLVLSLKKSIQTHIHEIDTFVTEAMKVLTVIPQSVEEIGDTNVQYSNLQDRRPEILPLFQEAEDKNRLLRTVAGGGVETVSNLRAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELDKFKARWDQLKPGDDIIETGQQNTMDQSAKSIKEKKIEFDDLEVIRKKLVDDCHHFGLEEPNFSLAYSISKDIESCAQIWALYEEFQQGLQDMAKEDWITYRAKIYLFEEFLINWHERLRKIEEHSVMTVKLQSEVDRYKMIIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVEKASELKDLNSRAQGEVTIREALRELDLWGVGAVFSLIDYEDSQNHTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAQLDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNKVDEDFRSIMMDIRKDSRVTTLTTHAGIRNTLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFDEESKHITAMKSLEGEVVPFKSKVLLSNNVEAWLNDLALEMKQTLKQLLKECVTAGRSSQGA---IDPSLFPSQILCLAEQIKFTEDVENAIKDHSLHQIEAQLVAKLERYTSVDTSSEDPGNSESGILELKLKALILDIIHNIDIVKQLNQVQVHTTDDWAWKKQVRFYMKS-DHTCYVQMVDSELQYTYEYQGNAPKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRTVCELLGKEVEINANSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILYSEGFKDAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLKK------NSTKQDVN----ENHIVVQALRLNTMSKFTFADCTRFDALIKDVFPGIDFKEVEYDELSSALKQVFEEANYEVIPNQMKKALELYEQLRQRTGVVIVGPSGAGKSTLWRMLRAALCKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPLEYRSNLENWIGDYFSKALQWVLKQNDYVVETSLVGTVMNGLSHLHGCKYHDQFIINLIRGLGGNLNMKSRLEFTKEVFNWARETPPDSHRP--MDTYYDCDRGQLASYMLKKPESLTADDF-SNGHIL-PVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQLRSTEIATIHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCAIDYPEREQLQTIYGAYLEAVLHKNLKNHSIWGSSSKIYLLAGSMVQVYEQVRAKFTVDEYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGVKELHLFDNILTSVLQGDWGSDILDNMADSFYVTWGAHHVSGGKTAPGQPLPPHGKPLGKLTSADLKDVIKKGLIHYGRDNQNLDILLFQEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTVTSLVSHMHGAVLFSPKISRGYEPKQFRNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLASGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANLNFIVNCESNPALHKKCQVLWMEGWSDSSMKKIPEMLFSETDGEEKYEKKRKDEKKRNSVDP-------DFIKSFLL-IHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSILLRIKQDEADSALQEITVSMQDASEQKTELERLKQRIAEEVVKIEERKSKIDDELKEVQPLVNEAKLAVGNIRPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNIPKEIRESVEELLFKNKASFDPKNAKRASTAAAPLAAWVKANVQYSHVLERIQPLETEQSGLELNLKKTEDRKRKLEDLLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLISQLDREHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKAAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSHLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEDFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLARLEESLLETLATSQGNILENKDLIESLNQTKASSALIQDSLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLASFLRLFQRALQNKQDSENTEERIQCLVNSLKHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQRIRDQLPSWIDQERSWAVATLKISLPSLYQTLCLEDGAFWRTYYHHSMCEQEFPSILAKKVSLFQQVLVVQALRPDRLQSAMALFACKALGLKELSPLPLNLKRLYK-ETLEIEPILIIISPGADPSQELQELASAERSSECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDSFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKRDNIHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYHVIDRLF-DGTKDVQWEFVHGLLENSIYGGRVDNYFDLRVLQSYLKQFFNSSIIDVLNQRNKKSIFPYSISLPNSCSILDYRAVIEKLPEDDKPSFFGLPANIARSSQRMISSQVISQLRILGRSVTAGCKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVSPPNDRQ----GSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLTWQSRWEGPEDPLQYLRGLVARTLAIQNWVEKAEKQVLLADTLDLSELFHPDTFLNALRQETARATGCSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNRLSENQHDSPSVSSVLPCYMGWTPQGSYGPYSPDECISLPVYTSAERERVVTNIDVPC-GGNQDQWIQCGAALFLKN 4305
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. UniProt/SwissProt
Match: sp|Q9SMH5|DYHC2_CHLRE (Cytoplasmic dynein 2 heavy chain 1 OS=Chlamydomonas reinhardtii OX=3055 GN=DHC1B PE=1 SV=2) HSP 1 Score: 3049.23 bits (7904), Expect = 0.000e+0 Identity = 1702/4353 (39.10%), Postives = 2616/4353 (60.10%), Query Frame = 3
Query: 300 ALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT-------DPKIQKLISELENGLGSIIRK--PLSKKSKYQTDETIVLGIFSIDDEIMFW---NDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSY------LENVFGLLNDIWQSETINPNYP--QSRMKTLMEIIANELVRIIQTQLNPLW------FWEDSYALVKESLTQAIEVCSHWIDMCDKLIK--RYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIF-------------------KECASAEM--PQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF-IHR---SRQGKVPPTKNASDEI-SKIVWSKQLEAKLNEILSITSNVLK-----DLDGFEKFLKETKNFLEEISN----WRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEK-LVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEM-KKFITLPNQFKGLNDSS--PGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDT------VSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNI---LSRQ-KQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILK-WIRGEGLSQDHWLEMFRLLNM----PRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDS---QNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVH---DLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCV-IQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQ--DEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLK-AIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQAC-IIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANE----SGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGI-LIPFLIDPSSNATAWLKNHFK--DRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNT-SEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLK-NKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSER-YNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFY-----GKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTD---SPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVE-KWAELSEKDELLSTI-------LDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVK----IGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQ-DKWIQSGVALFL 12986
++V K I +++ +G+ V T++ +P+SSLY+ ++++Y P++ S T D ++ +L+++++ GLG+ +RK P S + ++ + + + DEI FW +S +A + +++ + L+Q E++ A E S + ++ L W + + Q R + ++ L +Q +++ L W + V+ L A + + W+ L++ R H W + +Y+ +FQ RL EI ++R + +++ +++ E +++ F F + L + + +WK A + F R + P E I +LK +F + A + PQQ+ +RY+ L+ R I+ L E+ETL Q+ H ++ +F HR + KV P + I +I+W Q KL ++ + ++L+ D L+ T + E+ +R+EQ+ W + M+ L + +N +LM ++ + +++D+LV L+REVR L LG+ + K ++ + KFY ++LKQ A FYN I T+M+ CQ+ MML A++FEK L+ +Q K + W N L+ ++ +L + + + +NR LRK H ++ +K+V L G DL+R + KW + E+R+I ++E + + E+ W++H D QLYKALE QY GLE +N+ LPE+ V +V+RQ RLQ++P EE++ ++ K++ F+ LP + KG++D S PG F +++ N G Y AE LF +L+ L K+++W++LG+LDL+EF D + L+++D+E NF+ +K ++AEKLPNEI+I+C V+ AP+K S+D ++ + D L+ SLR+ D ++ ++ N ++ +++ +++I A + +++ + ++ N LLR +AGGG D ++++ WD F ++ F +E K N+ +SRQ ++F+ + N RWQ LKP SG+ L +Q+ + EL E L K+ E F+++ +F L+ E+ D+ + W ++ ++ +A DWLS R + + E+FL +W + + + L +EID Y +P LK +RG G HW ++F LL M P ++ E +TL H L+ A +++HA+ IK L+ +AQGE IR+A+ EL++WG F E S + LIKEWRD +++VGDNQ L+ SLK S YY F+D+ + WENKL+ L E L LNQIQRKWVYLEPIFG+ ALP ++ RFR VDE+FR M+ + +V++ + G+++ L M QL CQ+AL ++LEEKRS FPRFYF+GDDDLLEILGQ+ NP VI+SHLKKLF GI V F++D I M+S++GEVV+L V IT ++E WLG+L MK TL Q + L RM+++ SQ L L E + FT + E L + + KL A++ S F H LK ++L+LD +H D+ + L TEW W +QLR+Y ++ +G V + M +A F+YT+EYQGNA KLV+TPLTDKCYLTLTQGM +G GGNPYGPAGTGKTESVKALG RQVLVFNCDE D KSMGRIF+GLVKCG+WGCFDEFNRL+E VLSAVS QIQ IQ +K + + +++ V VD N+ IF+TLNPAGKGYGGR KLPDNLKQLFR +AM+ P+N+LIAEV+L S+GF +AK+L RKLV++F+LSRELL+PQQHYDWGLRALKTVL A E+ ++ Q NV D++ E ++I++++ L LT+ D F++LI D+FP + + + L A+ E M + Q +ML+++ QR+GV+IVGPSGSGKST+W+LL A ++G+ Y MNPKA+PR QLLG +++DTREWSDGVLT +AR+VVKEP E +SWIICDGD+DPEWIESLNSVLDDNRLLTMP+GERIQF NVNFIFE H L ASPAT+SR GM+F+S EA +V+ ++ WLK Q D D + ++++DFF K+ W A + + T+ G + +GLS+LK +K F L +GLG N+N + R F Y + E +V + L+ E E +D+ L++T ++ +NL W + + PF++ GPEGCGK +L++CF+++ VQV ++CSAQT+ +V+QKL Q C + + +G+ RP ++ R+ILYLKD+NLP+ DK+ T QLISFLQQ+I + G+YD NL+F+ ++ VQIV SM S+GR +LSTRFT++VR+ ++ YP ++ L IYT + +R++ S S L + M+EVYS ++ +FT +DY HY F +L+ W+ + RY L ++L++ +++E +R+F+DRLV D +++ +L+ T+ S + + W+ + + + + K L + + + + L Y RE ++L+++LF EV + V++ DRVL++ GGS+LL G SGVGRR+ LL+++MHN+ I+PKM + Y+LK F+NDLK L+ AGVE + ++L LEDHQ + +LEL+NSLL+ GEVPGL+T EEL L L +E +G S A +F+ RI+ LHI++ MD SN F C++NPA F CSVQWLE WS + +I + ++L ++S P+ G D L ++ + +H + + T+R Y+ + +Y +IY +K+ ++ +QN ++ G+ K++EA V L ++A +Q +L KQ EAD+AL I M A +R+ E+E L +T E V + +R+ +++EL+ ++P + AR AV +IK +++EIR+L+ PPD IRD+LEGVL+++G DTSW +M+ FLGK ++++I +DA +IT E R + +LL +SF+ +R S+AAAP+A W KAN+++S LE+++PLE+E ++L+ +LE +++ +K E+ + +D AVA + +F K T++A L+ + A +S+A L+ L E RW + L +L L + SLLAAA + Y+PS PE+ R + + W G +FD+ +FL++E E L+WK EGL +D LS +NA+VIL P +IDPS+ A+ WLK+H + + +E+ D F+T LEL+VRFGKTL++ EVD +EP+LYPLLR DL QGPR VVQ+GDK DYN F+LFL TRNP P LPPDA ++++ NFT T++GL+GQLL LT+Q +P+LEE+K+ +L++E++ K+ L+++E +LLQ LA +TGNIL NKDLL LN+TK S T+ ++L ES LQ SLD++R+ + P+A GS ++F+++DL +N MY FSL+ FL LF++AL+ + D T R L L +LV+ YV RS+F +DRL F +HM+ +P LF +W F G + D S P W+ ++ A S LA+A P+L + + D LW Q+A S +P + K++ FQ++L+++A RPDRLQSA+S F C L +K +SP +L + E ET +EP+L I +PGADPSQ+L E + + +G ER Y +VAMGQGQA+ + LL +C++NGDWL LKN+HL SWLP LEKEL L+ H +FR+++T+EPH F + LL+ SLK+T+EAPPG+K NL R+Y+ WS ++++ +G RA LF LAWFHA++QERR +IPQGWTKFYEFS ADLR+G +++ + ++ QW + GL ++AI+GGR+DNPFD +VL ++++R F+ V +G K+ +P+ + DY++II+ L D ++P F +PDNIDR++Q++ S++VI QL+ + + F++ W +L P+L W L G + +KA++ D R +TD +P+ F+ LERY LV + +L ++++VLKG++ L+ VQ+ LL P W WEGPE P DY R ++ KA A+E WA + L+L +FHP TFLNALRQ +ART+ SMD LK V W + + A +G L ++G FDG+ ++ ++ + +P +S+ W+ K+ P +Y+ + P+Y R K++ ++ +P ++ D W+ +G++LFL
Sbjct: 79 SVVLSKLRAGPIRTEDVPAGVAVATVAHSPLSSLYHTLKDVYSPLIKSQTAEGVPVLDKRLSELLAQVQAGLGTAVRKGVPASAQEVADPNQAPLQEVVTPLDEINFWAELTNSPNAGPIKSSALQVSSALEPLRQSFEQLSSDAPEGEGGSIGWEGAKELVDLTTNALRAAWPVKLPIGGWAMGQKRADNFLRVVGAALATYVQRRVDRLAAAGRGDLWSAPFGEVRAVLVGASGLMTRWVQESTALVEDWRLGVDTGGHDWEGAAFAD-AYVRSFQERLEEIYNMREMVDELAKLVGREEAGSLGVQQVFAPFQGLQALQVSDFNTHVWKAAHEDFERRMGPIEQRISQKLKELFASVIIPSLTSAIGPGRGGDRAAAGGSLIQPQQVFAEIKRYSSLMGRKNIASALQSEKETLAKQVDRHLDSVQAEFDAHRDSATGGAKVAPVGRVTASIVERIMWCMQTLQKLGKVSEVLKHMLRGGVAGDEGSGGAALRNTLGVVSELQKEVEIFRKEQYSAWEEWMSEELGEMANW-----KNSKLMTFDSQNSHVKTHFNDQLVLLLREVRQLQSLGFGVRKDILNEVEIANKFYRYGMVLKQRANFYNNIATEMVQCQKPMMLKDALDFEKVLMNPKDAQGKE---ITWRNAAALDGYVRRLNEVADRLAEKNRTLRKWHSVLSDKVVTLAGTDLVRHKDKWAAGVKEMREIFGRLEAEGYSRESQQVWRQHWDFQLYKALEVQYLSGLEMINKTLPEVEVKMVFRQHRLQYDPPLEELRIRHVKDLLNTFLGLPLRMKGVSDLSERPG---FFRPIVDANPTGIARVYAAAESLFTQLADELKKYQDWMVLGTLDLDEFADANLLEVSDWELNFRMLKAASRDAEKLPNEIRIECYKVSLAPVKGSIDEHMKKLQDTLVASLRRKTVAEKDQIEDFMKNGRELFTRQANTVEDIGLAGQEAKGLTAKLAEVQAARRRIDEKNKLLRQMAGGGRDAAFAVVDLTEVNNSWDAFTNQLQQFDAH----LEEQKGNLAVQISRQLEEFKGKVAGMNSRWQELKPKSG--PSGNPAVVLAKIQEYANAIKELREES---AKLYKEAEAFKIDVPDFELMTEMETDVMATKAHWDRYADFLRERDEMANRDWLSMRDQVWKIEDFLAKWTKATAGKSDDPIAVILTQEIDNYTLCLPHLKSCLRGAGWEDTHWNQLFGLLGMKTSGPAAVSKETVTLTHFLEKADLVVKHADVIKSLDAQAQGEAVIRKALTELKMWGMAREFTFTESTQSVAGRQRRTPLIKEWRDAMTEVGDNQSLVASLKQSSYYNMFKDEVSSWENKLSFLQEGLTLLNQIQRKWVYLEPIFGRGALPSQQQRFRNVDEEFRRTMTSLESTKKVVTFADIPGIRDKLPQMAQQLDVCQRALADFLEEKRSQFPRFYFLGDDDLLEILGQARNPAVIQSHLKKLFAGIQKVKFSQDQSTIQAMQSMEGEVVDLAPTVRITEQIETWLGDLTRSMKNTLQQQ-NEVLCAGRMNDEFRAAA------SQCLQLKEAVAFTEKAEVALKAGS------SGLAKLVTEMRAQLMKLTGSDFTGHHLLQLKKQALVLDFIHYCDVAEYLAKDKIGGTTEWGWTRQLRYYHRA--EGSVKVAMAEATFDYTWEYQGNAAKLVYTPLTDKCYLTLTQGMALGYGGNPYGPAGTGKTESVKALGQALARQVLVFNCDEEFDFKSMGRIFVGLVKCGAWGCFDEFNRLDEEVLSAVSQQIQTIQLALKEGAKTMMFMDKTVEVDKNAGIFVTLNPAGKGYGGRSKLPDNLKQLFRSIAMTVPNNELIAEVLLLSEGFNHAKDLARKLVSLFSLSRELLSPQQHYDWGLRALKTVLGIAGR--ELRDARKAGQ------NV-DAEIEAEIIIRSVAATKLPTLTFDDNSRFKALINDLFPGAKLTDARNEALEKALAEAAAACKMELTQQQIDRMLQLHLACEQRIGVIIVGPSGSGKSTLWELLEKAYERLGRKPIVYKMNPKAMPRQQLLGSMNMDTREWSDGVLTAAARKVVKEPLEQRSWIICDGDVDPEWIESLNSVLDDNRLLTMPNGERIQFANNVNFIFECHSLEFASPATVSRCGMLFMSDEAMEVERMLQRWLKVQATDNGDPGQMQSWMNDFFDKAFQW-ALSHPRAVETTKGGILDSGLSHLKLGPGSKQEFMAGLCRGLGSNMNPDIRNQF----YNDMARMSGEGGIMDV-----GVATDPLIVLGDELRER-GMDEADGG------LVVTPEVTQNLLMMAPWFKN--RDPFLVVGPEGCGKGALLDYCFKRIMGVQVAVVNCSAQTSAANVVQKLVQVCGKPVTTTSGKALRPPDNTRVILYLKDLNLPRPDKYNTCQLISFLQQLIAHHGYYDENLDFIRVERVQIVGSMTPPGSVGRHALSTRFTALVRIVTMGYPDRENLATIYTN----MAQRVLANSKTASSVSPAAL-SKAMLEVYSSVRERFTPNDYPHYEFNARELSDWINGIQRYSL-----EGGLTLVQAIAHEGLRVFRDRLVG-DHQEQFTSMLYGTLTSLLGYKPDAT---PWYTSTLGASAEERISGDLTKIKML-RWEQDTFAELVAEKLKGYEREHKELNLLLFPEVLERVSRFDRVLSQQGGSLLLCGNSGVGRRSLMLLLAYMHNMDFITPKMTKNYDLKSFRNDLKEVLRRAGVEAKPVMLFLEDHQLVNNAFLELVNSLLSGGEVPGLFTPEELAKELAPLDKARDEDPLYTGPSNSYA-FFSYRIRRNLHIVVSMDPSNEMFRSRCEANPALFTRCSVQWLEGWSVKGLQQIAAARL--------TELVESS--PELMKLGRDKLINHMIHIHASSGSQ--TTREYLALVSLYGQIYNRKRTQVLEQQNFLKGGLGKLAEAAVTVDTLSAEAEKQRVVLKAKQAEADEALVHIQDSMLKAADRRKEVEVLKKRTAIEEVEMKERRVKVEEELSEVQPLIDAARKAVGNIKKDNIAEIRSLKMPPDAIRDVLEGVLMVLGQQDTSWNNMKTFLGKGSVKDDIINYDAHKITPEIRARCAKLLAAKGNSFEDAVIRRVSVAAAPMAQWFKANLEFSKVLERVSPLESELHRLQSSLEESQRLIKQYEEELVQLDAAVASLKAEFSKKTSEAETLKISVDKAESVLSSARQLLDGLRGEKVRWEITVGTLGEQLKELPLSSLLAAAFITYLPSHPEEHRLKVTKDWCAYLGAAEFDVTRFLSSESEMLKWKAEGLPADGLSAQNAVVILNSTSRSPLIIDPSTQASEWLKSHLRVTGQNVEVTTMADQRFTTTLELAVRFGKTLVVAEVDKVEPILYPLLRMDLDRQGPRFVVQIGDKATDYNDTFRLFLVTRNPDPYLPPDARSLLAVTNFTVTRSGLEGQLLGLTLQKERPELEEQKSTMLRQEDECKVALAELERNLLQTLATSTGNILENKDLLDKLNETKTRSATVEKALTESKTLQASLDQQREVYRPIAARGSVMYFLLADLQALNQMYTFSLSVFLNLFKKALDRDTPPGGDVTARIALLAESLLELVFAYVSRSLFNADRLTFGMHMARHLQPSLFPEAQWAFFLGKPVPD-SASPPPKPSWVREEQAGAFSALAAAFPQLVAAAELADSALWAQWA--SGATDALPGKIAGGKVNPFQQLLLVKAFRPDRLQSAMSSFICGTLNIKSVSPPPFSLKALIEGETRPDEPVLFITTPGADPSQELSEYAAQTMGKERWYFEVAMGQGQAEKAVTLLRECAKNGDWLVLKNVHLAVSWLPSLEKELLMLQKHDNFRIFLTSEPHPKFPSTLLEMSLKVTFEAPPGMKKNLQRTYEAWSAEYLA-SGPPIRAQLLFVLAWFHAVVQERRTYIPQGWTKFYEFSFADLRSGMDVI-TLATRAGTAPQWPLLLGLLDDAIYGGRLDNPFDSQVLLTFLRRLFSAETVGAAGGKVRPLPGSKVVVPTTNHRADYVSIISALPDVDTPGLFCMPDNIDRTAQQVNSARVISQLKAMSLRADAAGGFNRAQWQAQLGPLLRLWDQLMSGASALKAAMKDIRARGTTDKGGAPIENFVALERYKGASLVALIDRTLGAIARVLKGTDTLSSGVQSSGAALLADVIPGSWDAAWEGPEAPMDYCRAVVAKALAIEGHWARCQQPGGGGLLDGSGGAGPLELSSVFHPGTFLNALRQQSARTLGCSMDMLKAVTSWETAKLKAAAGGAPVALLGGLIMQGATFDGSRLSPVAAEAPAFRAVPAMSMAWLHKDSPMAYA--SYMEAPLYMTSDRSKLLARVQLPVSGPEEMDGWVLAGLSLFL 4332
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. TrEMBL
Match: A0A1I8GFW0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013490g1 PE=4 SV=1) HSP 1 Score: 5044.94 bits (13085), Expect = 0.000e+0 Identity = 2487/4281 (58.09%), Postives = 3268/4281 (76.34%), Query Frame = 3
Query: 192 LDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKI-EEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSR-QGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSV--GSQSKTKNVVQ--WNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGL-EKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASL-PDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVS-AKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLK 12989
LD+F D+ ++L+ + SN+ K N++ F+K P ITPDN++S I+V++++E+P+S LY+ IQ +Y P+LL + DPK+Q L+++LE+G+ +RK S KSK + I S DE +W + S + D + R + + V+ E ++ ++ ++ ++ +L+++W+ P YP+SRM+ LMEI NE+VR +Q +L+ L W ++Y++VK+SL A++VC W+ C++L ++WK+Y P+ W L+Y+ F+ RL E+ + RTVHEQ+ ++L E+ + ++ EEAF+ + PL +NPYTEP+W+ AV KF H+ PAE + +L+ ++C PQQLL+ FQRY +L+ RP I LL ERE LL QL +H KQLR++F+ R++ G+ P+KN D+ ++I+W++QLE ++ EI + ++L DL GF+ F + FLEE+ NWR++ F+ W EM +DD N + L+ QG+LMEL Q DG L+VNYS+RLV L+REVRTL+ LGY+I K + D KFY A++LKQVA FYNTI+ QMI Q+ MML+ A+ FE+LVKS GS+ K VQ W++PEEL +I LQ+A++ I+ NR LRKQH +I EK+V+LMGIDLLRQQ +WK+ L EIR I+ I Q P+N LPW+ H D QLYKALE+QY +GLEALNENLPEIRVDL +QGRL F P FEEIK+KY++EMKKF+ +PN FKG+++SS G LI+PS+IERNA F C+ KA FLF+RL A L +FK+W++LG LDL+ FV+Q+CL+L +YEKN KA+K KG++AEKLPNEI+IDC+TVNC P+K S+DTLI N+FD+LLN+LR +IK D DA+LT +++ L KRPQ +DEI+EA NHA+F K+R + + ++ +E N LLR VAGGG++ ++ L KW+ FE+MMESFQMM+ EQIE+MKTN+ SR K + QD+ KF+ RW LKPGRDILD G + CL A++ IK+KK E EL + +L DCEHFQME EF L EE+ D+D +L W QFE++ +GLQ+LAKEDW+SFRSRYY+FEEFL QWF++LR E T+MT+RLQKEID YKD++P+LKW+RGE L DHWL++FRL+++PRG TLE LT ++L +SEII +AEA+KELN +AQGEV+IREAIRELELWGAGA FQL +Y DS N +SLIK+W+D++SQVGDNQC+LQSLKDSPYY+ F DKA +WE +LADLDEYLQNLN IQRKWVYLEPIFG+ ALPKE+ RF+RVD+DFR+I+ D+ R++RVLSLC+ SG++N L+TM+DQLQRCQKALNE+LE KRS+FPRFYFIGDDDLLEILGQSTNP VIK+HLKKLFQGI+DV+F++D +HI+ +KSLDGE+V LR ++L+T+EVE+WL L +EMK TL + L L+D++ + ++ YPSQ+LCL+EMI FT+R E L ++ L+ EL K+L+ YT + M S + I+ +LKLK+LILD +HNID++DQL+ N + +W W KQLRFY K D+ C I+MVDA F YTYEYQGNAPKLVHTPLTDKCYLT+TQGM MGLG NPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDV+SMGRIFIGLVK G+WGCFDEFNRLEEAVLSAVSMQIQ+IQDGIKN++ +I LL R ++VD NS IFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDN+ IAEVIL S+GF++ KELGRKLVAIFNLS+ELLT QQHYDWGLRALKTVL+ A L++ K +K N+ +E D E +L+VQALR+NTLSKLT++D F+SL+KDVFP +D K+IEY LA I EV+ EQ +V + Q KK LEVYEQ QRMGVVIVGPSGSGKST+WK+LR A+ K G+ VK YVMNPKA+PRTQLLG ID+DTREWSDGVLT++ARQVVKEPQE+QSWI+CDGDIDPEW+ESLNSVLDDNRLLTMP+GERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS EATD++++V SWL Q E D+ LLS Y++D+FY ++DW+ K N++ + T+ VGTV NGLS+LK ++NKAHF++ LI+GLGGNL E +RE FA V+ +T E P+ + L+ +F+ + RL +YS + + S ++S K P+ILT+ IQRNLD FK WL ++T+QPFI++GP+GCGK ++L +CF +++S+QV LHCSAQTTP H+LQKL Q C++I+SNTGRVYRPK+ ERL+LYLKD+NLPK DKWGTSQL++FLQQV+TY GFYDSNLEFVGL+GVQIVCSMN+S+++GR LSTRFTS+VR+CS+ YP K+QL IY++YLK + +++P+HP+WS +SK+ LA+TM+ ++ ++ +F+ D+ SHYLFTP DLT+WV +LLRYDLP +A ++E+V+YE+ R+F+DRLV SDAR R D +L + I S+WS + D L WFVTWGSREPQAAGAPPP QGK+LGKL+ E L +D+GLLQYSRE +DL+I++FKEV D+VA+ DRVL +PGGS+L+AGKSGVGRR+T+LLV+HMH + +++PK+ RGY +KQFK +LK+ +Q AG++GE ++ LLED Q LE Q+LE+INSLL+SGEVPGLYT EELEP+L L+DLA+ESG RG LAN+ A R++ LHI+LIMD + NF I C+SNPA FK C+VQWL WSR+SM+++ ++L+ ++ REEGS+L + K + L+G ++L FL +H++ P +T R YIN + Y +Y KK++I+ ++ H++ G+ K++EAK++V ELK KAA+Q LLTEKQ EAD+ALK+IT M A E++ EMEKL+ +T EEN +L KR A ID EL + P V++A+ AV IK+ LSEIR+LRAPPD IRDILEGVL +MG +DTSW SM+NFL +RG+ EEI+TF+AR+IT E R +VE+LL R K SFDP NAKRAS+AAAPLA W KANV+YS+ L++I PLE+EQ +LK+NL+ +E + L+ +++VD VAG + F+KF+ DAAKL+ +L ANETI AAE+LV KL+ E +RWN+Q+ +++EL L ++SLLAAA + YMP++PEDQR +++ W+ T + + FD+R+FLT+E EQL WK EGL SD+LS+EN +VILQ L PFLIDPSS AT WLK H KD+KLE +NQQD+NF+T LEL+VRFGKTLIIQEVDG+EPVLYPLLR +LI+QGPR VVQLG+K+IDYNP+F+LFL TRNP P LPPDA AIV+TVNFTTT+AGL GQLLA T+QH KP+LE +K+ LL++EE LKI+L+++EESLL+ELA A GNIL NK+LL SLN+TK SS TI +SL ESV+LQ+SLDEER AFLPLAE GS L+FVI DL+KINNMYRFSL++FL LF RAL + S +MR +L+ L+ LVYEYVCRS+FK+DRLMFALHMS RPDLF+ QEWE F G +SD TVP WI +R + +L ++PEL L +D +LW F++SSECE P L+ +LS FQK+L IQALRPDRL +AL+QF L+L +SP ++NL ++E ET + EP+L++IS G+DPSQ+LQEL+ + IGSE Y+QVAMGQGQ++I L LL CS+ GDWLCLKNLHLVTSWLPVLEKELN L+PH FRLW+TAEPH F ILLQ+SLK+TYEAPPGVK NL R+Y+ W+ F+S GS R+ LF+LAWFHA++QERRNFIPQGWTKFYEFS ADLRAG +I+D+++KK I W+F++GLFENAI+GGRVDN FD+RVL SY+ + F+ + + G I++P + R+++ + L ++++PS+F LP+NIDRSSQRI+SSQVI QLR+LQR V G KFDKD+W++EL+P+LN WK LNQG +I+A P S S + +P+ F+ LER+N+IKLV++VHSSL SLSKV++GS+LLT ++Q L+E LL G+TP WL +W+GPE+P Y+ L+ +A A++ W + + LL++ LDL ELF PDTFLNALRQ TAR SMD LKF C WG + AK + ++ +EGC FDG +TE +RDS S+ +P V++ W+ K + YS D ISLP+YYD RD++V ++D+PC SG QD+WIQ G ALFLK
Sbjct: 34 LDEFLDDGKVSLLIASEYGGRITLSNKPQDQQKQKNSVAFMKLRPDPITPDNLHSDILVSSMTESPLSCLYHSIQKLYAPMLLEGSTTTEKLDPKLQTLLTDLESGIAIALRKDSSSKSKDDSKN--FAHILSPSDEFHYWAEEASRARGDA-KDRAAVFHNIFKSVSGEYSGLSELTIADALDLVDATQDILDELWKQSETTP-YPESRMRHLMEITGNEIVRYLQNRLSSLALWTETYSVVKDSLDLAVQVCDRWLRACEQLTGQFWKRYAPNPWKGSVQ-RLTYLEKFKQRLEEVLAARTVHEQMCRLLTDSEKVDARLGEEAFESLQKVQPLNFNPYTEPLWRAAVSKFESHLAPAEARVVGKLRGQLRQCEG--RPQQLLKEFQRYKELVRRPTIGNELLAEREQLLGQLTLHAKQLRDEFVQRTQGSGRALPSKNVPDQANRILWTRQLELRMKEITDVGHSLLGDLGGFKAFSQTASTFLEELQNWRRDAFDDWASEMQSLIDDP-NKPMSLETQGQLMELRQSDGKLHVNYSERLVTLLREVRTLNSLGYEIPKKIQRVHDVASKFYRHAIVLKQVAHFYNTIDAQMIHSQKPMMLEPAMKFERLVKSPKPGSKQKGSGGVQVTWDSPEELEAYIRVLQEAANDIMGINRKLRKQHHVISEKVVDLMGIDLLRQQHRWKEGLQEIRLIMTSIAAQGVSPDNMLPWRAHWDRQLYKALEHQYRLGLEALNENLPEIRVDLTIKQGRLVFKPPFEEIKAKYYREMKKFVNIPNVFKGVSESSEG--LIYPSIIERNAEAFNNCFVKACFLFKRLEALLTRFKDWVVLGGLDLDAFVEQNCLELAEYEKNVKALKVKGRDAEKLPNEIRIDCVTVNCQPMKNSIDTLINNLFDSLLNALRLSIKRDADECDAFLTRAMETLGKRPQTVDEISEAGSNHAQFGKERPQQKGLLESAEVKNRLLRGVAGGGVEFLAPLNAKWETFEIMMESFQMMILEQIEMMKTNVESRIKAYVQDLEKFSARWNQLKPGRDILDDGDQERCLAAIKVIKEKKEEFSELEKTRESLTSDCEHFQMERPEFPLAEELKADLDTVELEWGQFEKFNSGLQDLAKEDWISFRSRYYVFEEFLGQWFDRLREEEPTSMTVRLQKEIDKYKDVLPVLKWVRGEPLGPDHWLDLFRLIHLPRGTTLERLTFGNLLSVSSEIIANAEALKELNLRAQGEVSIREAIRELELWGAGAQFQLTDYEDSHNRKVSLIKDWKDLVSQVGDNQCILQSLKDSPYYKSFADKATLWETRLADLDEYLQNLNLIQRKWVYLEPIFGRGALPKEQPRFKRVDDDFRAILQDIARDSRVLSLCNQSGLRNNLTTMLDQLQRCQKALNEFLEAKRSIFPRFYFIGDDDLLEILGQSTNPTVIKTHLKKLFQGIHDVEFDQDAKHIVAIKSLDGEIVPLRREILVTAEVESWLSKLADEMKATLRELLVNCLEDMKSARHG--ALDPSAYPSQVLCLAEMITFTSRAESTLKSGSLSNLRSELEKQLDAYTRSDMGQSGEEAAIL-ELKLKALILDMIHNIDVVDQLMAHNTRRQEDWMWQKQLRFYLKPSDKCCEIRMVDAVFEYTYEYQGNAPKLVHTPLTDKCYLTMTQGMFMGLGANPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVQSMGRIFIGLVKSGAWGCFDEFNRLEEAVLSAVSMQIQVIQDGIKNRLPKIELLGRTIDVDPNSGIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNEQIAEVILFSEGFRSGKELGRKLVAIFNLSKELLTQQQHYDWGLRALKTVLRSAGGLVKTAKKALKE--NEKLE----PDAEARLVVQALRINTLSKLTFSDCFRFDSLVKDVFPTVDFKDIEYQVLAEKIREVVAEQKLVLNENQVKKCLEVYEQTSQRMGVVIVGPSGSGKSTLWKVLRQAMIKTGKMVKQYVMNPKAMPRTQLLGSIDLDTREWSDGVLTFAARQVVKEPQEVQSWIVCDGDIDPEWVESLNSVLDDNRLLTMPNGERIQFGPNVNFLFETHDLSCASPATISRMGMIFLSDEATDIRAVVQSWLSDQPEKDRELLSAYIEDYFYSAVDWVLKTNDYCVDTTLVGTVLNGLSHLKGVQNKAHFAISLIRGLGGNLPEATREKFATEVFAITSESPPDSKRP--LDCFFDSEFGRLQSYSNMMDTDFSPSSIISTK---PPVILTSAIQRNLDCFKDWLQAETRQPFIITGPDGCGKGMLLQYCFDQVRSLQVAVLHCSAQTTPTHILQKLGQCCMVISSNTGRVYRPKDCERLVLYLKDVNLPKPDKWGTSQLVAFLQQVLTYNGFYDSNLEFVGLEGVQIVCSMNASTTVGRHKLSTRFTSVVRICSMGYPDKEQLQTIYSSYLKVIFDKIVPRHPVWSSSSKMHALASTMVSIFDSVRGRFSPDERSHYLFTPRDLTRWVRNLLRYDLPAL--ESAEQMMEVVAYEAFRLFRDRLVDSDARGRFDNLLGSIIRSDWSSDAIDQLQSSWFVTWGSREPQAAGAPPPPQGKTLGKLSFEDLSAVVDKGLLQYSRENKDLEIVIFKEVLDHVARADRVLCQPGGSLLMAGKSGVGRRSTALLVAHMHLMTVMTPKIARGYTVKQFKTELKAAIQKAGIDGEQVLFLLEDFQLLELQFLEMINSLLSSGEVPGLYTPEELEPLLTPLRDLASESGFRGPLANFLASRVQANLHIVLIMDFDHPNFTIRCESNPALFKQCAVQWLSDWSRESMVRVAHLLLTRVAREEGSKLRKEEPKQR-HLSGGESLLKLFLHVHESVPAVSATPRRYINLLNTYKSLYSGKKSKIQEKKEHLKAGVSKLNEAKDLVDELKRKAADQQVLLTEKQTEADEALKEITQAMSDAGEQRAEMEKLSEQTAEENKLLQKRNAEIDLELKDVMPLVEEAKKAVGSIKTESLSEIRSLRAPPDTIRDILEGVLTLMGNLDTSWQSMKNFLARRGVTEEIKTFEARKITPELRSKVEDLLRRNKASFDPVNAKRASVAAAPLAEWTKANVQYSHVLQRIQPLESEQAKLKKNLDKSEARRTQLKNALAEVDNKVAGLKDKFQKFSTDAAKLKVDLDKANETIQAAENLVSKLDGEHQRWNQQMQSMDSELDELPVRSLLAAAFICYMPAAPEDQRLSQVKTWLSATEISDHFDLRRFLTSESEQLIWKSEGLPSDDLSVENGIVILQCSLRPFLIDPSSRATDWLKTHLKDQKLEAINQQDANFTTSLELAVRFGKTLIIQEVDGVEPVLYPLLRSELIAQGPRFVVQLGEKVIDYNPEFRLFLTTRNPNPDLPPDAAAIVTTVNFTTTRAGLTGQLLAATIQHEKPELEVKKSELLKQEEDLKIKLAELEESLLEELAKAKGNILENKELLESLNQTKASSTTIQESLSESVRLQVSLDEERSAFLPLAEDGSKLYFVICDLAKINNMYRFSLSAFLSLFHRALASEGESPTPSMRIQALLTRLKHLVYEYVCRSLFKADRLMFALHMSRGMRPDLFREQEWEAFAGLIVSDA--HAGTVPGWISEERRRDVQSLMQSLPELSQELRFEDANLWRDFSRSSECENAFP--LEKRLSAFQKVLAIQALRPDRLFTALNQFAMAALDLNEISPPNVNLKVLFEKETSATEPVLVLISAGSDPSQELQELAGQTIGSENYHQVAMGQGQSEIALKLLRDCSREGDWLCLKNLHLVTSWLPVLEKELNQLRPHAQFRLWLTAEPHPKFPPILLQTSLKVTYEAPPGVKRNLSRTYETWTPQFMSLQGSVVRSCTLFALAWFHAVLQERRNFIPQGWTKFYEFSNADLRAGADIIDRLVKKHQDAIPWEFVYGLFENAIYGGRVDNVFDLRVLKSYLHQCFDPNNLTKGNRRLGPIKVPGTTNHREFVDAVATLPEFDNPSYFGLPENIDRSSQRILSSQVIGQLRVLQRVDVKGVKFDKDLWAQELSPILNLWKKLNQGHQLIQAKANPPS--HSDSANPIKTFVLLERFNAIKLVQYVHSSLASLSKVIRGSQLLTSDIQKLAEALLLGETPLNWLSRWDGPEDPLLYLHGLVGRAVALDTWLDKVMNENLLNSPLDLSELFKPDTFLNALRQQTARQAGCSMDSLKFACSWGRGGIGQAKLTAQLVGFQLEGCTFDGNQLTENSRDSPSVSAVPAVTIAWIAKTSSDVYSPDQCISLPVYYDQNRDRVVARLDLPCNSGTQDQWIQCGAALFLK 4281
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. TrEMBL
Match: K1PYA0 (Cytoplasmic dynein 2 heavy chain 1 OS=Crassostrea gigas OX=29159 GN=CGI_10003816 PE=4 SV=1) HSP 1 Score: 4974.07 bits (12901), Expect = 0.000e+0 Identity = 2480/4339 (57.16%), Postives = 3229/4339 (74.42%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHFPNQNSKFV-----NEECLDKFFDNLDNNV-LVVKFIDNK-----FIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLG-IFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNL--NLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQ----GKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKS--VGSQSKTKNV-VQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMS-LSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTS-DNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSRE-----XXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTC--PVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQ-------GILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD-KSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFN-DSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RKD I T ++F S + L+ F D D N+ L I+ + FSN+L + +VF K SP +ITPDN+++ IV+T+ ++P+S+LY+ +Q IY P++L D DPK+Q LISELE GLGS IRK K + D LG I S DE +W D ++ R ++ + + +++E + + + + +E L+D+W+ + YP+ RMK LM++I L R +Q +L+ + W ++ +VKE L + +C W+ +C+ L ++WK + H W + + NL ++N RL EI +LR VHEQ ++L E+++ + EAF F+ + PL YNPYT P+W AV ++ + + P E I +L+ FK PQQLLR FQRY +LI RP I ++ ERETLL QL ++ ++ +DF R+ Q +P KN + ++ IV+ +QLEAK E + +L DL GF KF K+ + L+E+ WRQEQF+ W +++T R+ D + + L+ GRLMEL+ K G L VNY DRLV L+REVR LSG+G+ + + + QKFY V+LKQVA FYNT++ QMI CQQ MML++AI FEKLVK+ GS++K +NV + W++PEEL+++I KLQKA+ + ++NR LRK H +CEK+ LMG+DLLRQQQKWKD L EIR ++ + Q ++ PWK H D QLYKALE+QY +GLEALNENLPEI+V+L YRQ +LQF P FEEIK+KYF+EMK+FI++PN FKG+ D + LIFP++I+RNA GF+ CY+KA+ LF+RL ++FK+W LG+LDL++FV+ + DL D+EKNFK +K +G++AEKLP++IK+DCITVN P+K +D IQ +FDALLNSLRK I ++S+D +L ++++ LSKRPQ+++EI EA HAEF K + I+ K+E N LLR+VAGGG+D++S LQ WDKFELMMES Q+M++EQ+EVMK N+ SR K F Q++ KF+ RW LKPG D LD G + C AVQ IKDK+ E EL + L DCEHF ME + + E+ D+ + MW +E++ GLQ LAKEDW+SFRS+ Y+FEEFL+ W+EKL++ E TTMT+RLQK+ID YK+++P+LKW+RGE LSQDHW+E+FRLL+MPRG TLE L H+L+A+ EIIR+A+A+KELNQ+AQGEVTIREAIREL+LWGAGAVF L EY DS N I LIK+W+D+++QVGDNQ LLQSLKDSPYY+ F+DKA+VWE +LADLDEYL NLNQIQRKWVYLEPIFG+ ALPKE+ RF+RVD+DFR+IM DV R+NRVLSL S +G++NLL+TM+DQLQRCQK+LNE+LEEKRSLFPRFYFIGDDDLLEILGQSTNP VI++HLKKLF GI+ V+F+ + QHI+ MKSLDGEVV L +V I EVE WLG L +EMK TL + L L+D + S ++ KYPSQILCL+E I FT CE +++ + KEL +L YT+ + S+D+ V DLKLK+LILDT+H ID++ QL+ +S EW W KQLRFY K C I MVDAEF YTYEYQGNA KLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKA+G LFGRQVLVFNCDEGIDVKSMGRIFIGLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ+IQD IKN+ LL R V++D NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMS+PDN+ IAEVIL S+GFK KELGRKLVA+FNLS+ELLTPQQHYDWGLRALKTVL+G NLL+ K K DS FE KL+VQALR+NTLSKLT++D F +L+KDVFP I+ K+IEY+ LA AI V KE N+ + Q KK LE+YEQLRQR GVV+VGPSGSGK+T+W++LR L+K+ + VK Y MNPKA+ RTQLLG IDIDTREW+DGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+K++VTSWL Q E +QH+LS +++D FYK++DW+ K+N+F + TS +G V NGLS+L ++NKAHF+VCLI GLGGNLNE SRE FA V+ T E P+ + L+ +++E RL+TY+ E +LS D + + P++ T D+QR LDYF WL D +QPFIL GPEGCGK ++L HCF++L+S QV +HCSAQT P HVLQKL+Q+C+++N+NTGRVYRPK+ ERL+LYLKD+NLPK DKWGT QL++FLQQVITY GFYD NLE+VGL+GVQIV SMN+ + +GR L+TRFTSIVR+C I YP K+QL IY AYL P+L R + +HP+W +KV LA +M+++Y QL+S+FTVDDYSHYLFTP DLT W LSLLRYDL + + ++ +LEI +YE+ R+F+DR+V ++ + + D IL +T+ ++WS + D+L+ +FVTWG+R AAGAP P GK LGKL ++ L I+RGL YSRE RDLDI++F+EV DN+A++DRVLT PGGS+L+AG+SGVGRRT LLV+HMH + L SPK+ R Y +KQFKNDLK+ +Q AG+EGE +VLLLEDHQF+EPQ+LE+INSLL+SGEVPGLY+ EELEP+L L+D+A+E+G RG+L N+FA RIK LHI +IMDCSN +F +NC+SNPA +K C+VQW+E WSRDSM+K+PYML+ K P+ EG+ + + + + +L+G + L FL +H++C +T R YI F+ Y +Y KK +E RQ+H+Q G+ K++EAK++V ELK KA EQS LL EKQ EAD AL++IT MQ A+++K EME+L + EE+ +L RK AID ELA +EP V+ A+ AV +IK+ LSEIR+LRAPPD IRDILEGVL +MG DTSWVSM++FL KRG++EEIQTFDAR+IT E R VE L+ + KDSF+P AKRAS+AA PLAAWVKANV++SY LE+I PLENEQN+L RNL+ AE +M L++ + +VD VA R FE T +AA+L+ +L NETI AAE LV KLE E++RW++Q+ EL+ EL L ++LLA+A + Y+ +PED R+ M W E G++ FD R+FL+TE EQL WK EGL SDELSMENALVILQ PFLIDPSS AT WLK H KD++LE++NQQD+NF+T LEL+VRFGKTLIIQEVDG+EP+LYPLLRGDL+SQGPR VVQ+G+K IDYN +F+LFL TRNP P++PPDA +IV+ VNFTTT+AGL GQLLA T+Q+ KP+LE RKT LL+ EE LKI+L+KMEESLL+ELANA GNIL NK+LL SLNKTK SSITIS SL ESV+LQ SLD+ER+ +LPLAE GS ++FVISDL+KINNMYRFSL +FLR+FQ+AL T + + + R +L L+ LVYEYVCRS+FK+DRLMFALHM H +P+LF+ EWE FTGT +S+ K+D +P WID +R A++NL + P+L+ VLN D LW F++S+ECE+E P ++ ++SLFQ++L++QA+RPDRLQ+A+ F C L +K LSP S+NL ++ E+ET+ +EPILIIISPGADPSQ+LQ+L+ + IG ++Y+QVAMGQGQ+DI + LL +CSQNG+WLCLKNLHLVT+WLP LEKE+N+LKPH DFRLW+TAE H F TILLQSSLKITYEAPPGVK NL+R+Y++W+ ++ISK+GS RA ALF+LAWFHA++QERR +IPQGWTKFYEFS++DLRAG +I+D++I K+ + +WKF+HGL+E AI+GGRVDN FD+RV+ SY++++F+ +++ G G ++LP++ + RDY+ I +L +++ PS+F LP+NI+RS+QRIIS+QVI QL++LQR KFDK+IW+ EL P+LN WK LNQG +I + + ++ ++P+++F++LE+YN+IKLV+ +H SL SLSK+++G+ LLTKEVQNL+ LL +TP W +W+GPE+P Y+R L+ +A A++ W + ++ LL LDL +LFHPDTFLNALRQ TAR + SMD LKF W G AK VK+G L +EGC FDG ++E RDS S+ +PP V W+ K+ P+ Y DD+IS+P+Y RD IVT++D+PC G Q W+Q G ALFLKS
Sbjct: 5 DSRKDYILATTANYFGLGVSDAAITALQDSTALNSFLD--DGNIDLCAGRIETRGSTKRLGFSNKLEPNESKEKVIVFFKVSPEVITPDNLHTNTIVSTMIDSPLSTLYHAVQKIYAPLMLEDGKWSRTLDPKLQSLISELEAGLGSAIRKQ-DPSFKGKGDNADNLGSILSPVDEFQYWGDMA------RSDERASQFVDLFKPISKEFGGLDTMEMMDVMELVEIAQDTLDDVWKFVDFDA-YPEPRMKHLMDVIGGSLGRYVQRKLSEVDLWTGNFGMVKEDLRSGVAICERWVGVCETLTTQFWKSFRLHPWKGEKYVPENLKQLAN---RLEEILTLRIVHEQQIRLLSSSEQKDLRTAEAFHPFMGLNPLQYNPYTMPLWNAAVAQYDKIMAPVEQKIAGKLRSQFKGLEG--YPQQLLREFQRYKELIKRPSIKKEMVSERETLLGQLNVNLRETEDDFQKRTGQRAGNKGIPKGKNLPEIVNAIVFVRQLEAKTEETIKTAETLLGDLSGFSKFRKDAQELLDELRQWRQEQFDDWTRDITDRISDP-KEPLCLETNGRLMELNHKTGKLQVNYGDRLVTLMREVRQLSGMGFAVPAKIQHVCNTAQKFYRHGVVLKQVAHFYNTLDQQMISCQQPMMLNSAIAFEKLVKNPKTGSKAKGENVEITWDDPEELDKYIHKLQKAAERLTTENRKLRKCHLTVCEKVQTLMGVDLLRQQQKWKDGLMEIRHLMANLVQQGFSSDHMRPWKAHWDRQLYKALEHQYQMGLEALNENLPEIKVELTYRQQQLQFRPPFEEIKAKYFREMKRFISIPNNFKGVGDDT--TNLIFPAIIDRNAEGFITCYRKADALFKRLETAQHQFKQWCALGALDLDQFVEDNLKDLPDWEKNFKGLKARGRDAEKLPSQIKVDCITVNTNPVKAVIDDHIQRLFDALLNSLRKAISTEVNSIDGFLKDAMETLSKRPQSVEEIGEANGKHAEFLKKKKEIQPLFMKAEAKNKLLRSVAGGGVDSLSSLQAFWDKFELMMESHQLMVKEQVEVMKNNVDSRVKAFIQEVEKFSARWHQLKPGDDALD-GDKKKCEAAVQVIKDKRQEFAELEKTRETLVHDCEHFGMELPDLEVANELKADMSNFESMWGLYEQFNNGLQELAKEDWISFRSKAYMFEEFLSSWYEKLKSEEPTTMTVRLQKDIDKYKNVLPVLKWVRGEPLSQDHWMELFRLLHMPRGTTLEKLNFGHVLNASDEIIRNADALKELNQRAQGEVTIREAIRELDLWGAGAVFTLTEYEDSNKNGIMLIKDWKDLVNQVGDNQALLQSLKDSPYYKSFEDKASVWEQRLADLDEYLHNLNQIQRKWVYLEPIFGRGALPKEQGRFKRVDDDFRNIMMDVRRDNRVLSLVSKAGLRNLLTTMLDQLQRCQKSLNEFLEEKRSLFPRFYFIGDDDLLEILGQSTNPNVIQTHLKKLFAGIHSVEFDDNAQHILAMKSLDGEVVPLLRKVKIMPEVEIWLGKLADEMKETLQELLRECLKDAKGGKGS---LDPGKYPSQILCLAEQIRFTEMCEHAISKGTLPQYNKELASQLESYTDVDLGDSSSDTQTHVLDLKLKALILDTIHAIDVVHQLMQAGTRSPDEWMWNKQLRFYMNRKGL-CSINMVDAEFEYTYEYQGNAAKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKAMGGLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQVIQDAIKNRAPMAELLGRNVDIDHNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSKPDNEQIAEVILFSEGFKAGKELGRKLVAVFNLSKELLTPQQHYDWGLRALKTVLRGCGNLLQQAKKKGAK---------VDSKFEAKLVVQALRINTLSKLTFSDCARFNALMKDVFPGIEFKDIEYEELAEAIRSVCKEANLRVNEIQIKKALELYEQLRQRTGVVVVGPSGSGKTTLWRILRQGLHKLNKEVKKYTMNPKAMHRTQLLGQIDIDTREWTDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSCASPATISRMGMIFLSDEDTDIKAVVTSWLSSQPESEQHILSGWIEDHFYKAVDWVLKQNDFVVETSLIGVVLNGLSHLHNVRNKAHFAVCLIHGLGGNLNEGSREAFAKEVFAWTQEMPPDSRRP--LDTFYDENMGRLMTYNMEATRDLSADNFTTGGSL--PVVRTGDVQRGLDYFAPWLQPDNKQPFILVGPEGCGKGMLLKHCFEQLRSTQVAVVHCSAQTNPTHVLQKLSQSCMVLNTNTGRVYRPKDCERLVLYLKDLNLPKPDKWGTCQLVAFLQQVITYNGFYDHNLEWVGLEGVQIVASMNAGTGLGRHKLTTRFTSIVRICCIGYPDKEQLQAIYGAYLTPILNRQLGRHPVWGNPAKVYALAGSMVQLYEQLRSRFTVDDYSHYLFTPRDLTNWCLSLLRYDLNAGAKEGSSDHVLEIWAYEARRLFRDRVVGTEGQNKFDSILMSTVRADWSANIFDNLDTDYFVTWGARHEDGGPAVAAGAPLPSTGKPLGKLNTDDLTAVIERGLKLYSRENRDLDILIFREVLDNIARVDRVLTLPGGSLLMAGRSGVGRRTAVLLVAHMHQMHLFSPKVSRAYGMKQFKNDLKTVMQLAGIEGEQVVLLLEDHQFVEPQFLEMINSLLSSGEVPGLYSPEELEPLLSPLRDMASEAGFRGTLINFFASRIKTNLHIAMIMDCSNNSFTLNCESNPALYKECAVQWMESWSRDSMVKVPYMLLTKPPKIEGASIGEKK-RHQRKLSGGEELLKCFLHVHESCIQANMGATPRRYIAFLNTYQTVYSNKKAGVEKRQHHLQAGVSKLNEAKQLVDELKRKAGEQSVLLAEKQAEADTALREITISMQNASDQKNEMEELKRQAAEEDKVLQTRKKAIDRELAEVEPLVQAAKSAVGNIKTESLSEIRSLRAPPDTIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVKEEIQTFDARKITPEIRKGVEALIRKSKDSFEPAAAKRASVAAEPLAAWVKANVQFSYVLERIEPLENEQNELIRNLKKAESRMDKLKRALDEVDAKVASLRNRFETLTKEAAELKIKLDKENETIQAAETLVTKLEGEYQRWSRQVGELSDELKELPKRALLASAFITYLAQAPEDVRRNFMNTWSEALGVQHFDCRRFLSTESEQLIWKSEGLPSDELSMENALVILQINDIPAGSTQRPFLIDPSSRATDWLKIHLKDQRLEVINQQDANFTTALELAVRFGKTLIIQEVDGVEPILYPLLRGDLVSQGPRFVVQIGEKSIDYNEEFRLFLTTRNPNPEIPPDAFSIVTEVNFTTTRAGLTGQLLAATIQNEKPELEVRKTELLKTEEDLKIQLAKMEESLLEELANAKGNILENKELLDSLNKTKASSITISDSLTESVRLQASLDQERNTYLPLAESGSRMYFVISDLAKINNMYRFSLAAFLRIFQKALKTKQDGSGTDHRIKALTQRLQNLVYEYVCRSLFKADRLMFALHMVHGMKPELFEENEWEGFTGTLVSEMKADGGRGMPSWIDQERQTAVTNLKTNFPKLYQVLNFDDGSLWSSFSRSNECEKEFPSVIEKRISLFQQLLVVQAVRPDRLQTAMGLFACKALGMKELSPPSVNLKRLLETETLPSEPILIIISPGADPSQELQDLAEQTIGGDKYHQVAMGQGQSDIAMQLLRECSQNGEWLCLKNLHLVTAWLPQLEKEINTLKPHDDFRLWLTAEVHPKFPTILLQSSLKITYEAPPGVKRNLMRTYESWNPEYISKSGSVLRAQALFALAWFHAVVQERRMYIPQGWTKFYEFSLSDLRAGADIIDRLI-KTGTDQEWKFVHGLYEFAIYGGRVDNTFDLRVMVSYLRQFFDGNTLSQGRNKRLGPLRLPTSTNFRDYVEAIEELPEFDKPSYFGLPENIERSAQRIISNQVIGQLKVLQRADAKANKFDKEIWATELGPILNLWKKLNQGSQLINSKIKPPSDKTGQEAPIISFIKLEQYNAIKLVQSIHQSLASLSKIIRGTMLLTKEVQNLAAALLNQETPLDWQGKWDGPEDPMQYLRGLVTRATAIQTWVDKADHGNLLRDTLDLSDLFHPDTFLNALRQQTAREVGCSMDSLKFAVSWRGGVQGAKTQVKVGGLQLEGCSFDGARLSENQRDSPSVSAVPPCQVAWIPKDAPDPYGMDDVISIPVYTSSERDHIVTRMDLPC-GGNQSLWLQCGAALFLKS 4304
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. TrEMBL
Match: R7UM87 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_174571 PE=4 SV=1) HSP 1 Score: 4963.28 bits (12873), Expect = 0.000e+0 Identity = 2448/4335 (56.47%), Postives = 3231/4335 (74.53%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHFPNQNSKFVNEEC-----LDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTD--ETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGK---VPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKS--VGSQSKTKNV-VQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSA-------DSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTS-DNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXX-----XKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPV--EFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNIT---VPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRN-IQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVN--GSGN-FYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RK+ I T ++F Q ++ C L+ F D+ VLV + K FS Q++T+ K +VF KT P ITPDN++S + V+T+ ++P+++LY+ +Q +Y PILL D DPK+Q L++ELE GLGS++RK + +D E + GI + DE +W +S A + ++ R LQ + E + S++L E +E L+D+W+ P YPQ RMK L+ +IA R +Q QL L W+ Y VK+ L + +C WI C L ++WK+Y P+ W D + Q RL EI +LR+VHEQ+ ++L H+++Q+ +++AF F +LPL +NPYT+P+W AV ++ R + PAE I +L+ F QQLLR FQRY DL+ RP +S L ER LL L+ +Q R+DF+ R+ G +P KN + ++ IVW +Q+EAK+ E + +L DL GF+ F K+ + LEE+S+WRQ+ F++W++++ +++D N+ I L+ GRLMEL+ +DG LYVNY DRLV L+REVR+L+ LGY I ++ AA+ G KFY VILKQVA FYN+I+ QMIP QQ+MML++A+ FE+++K+ G +SK V V W+ P+EL +I+K+Q A++ + S+NR LRK HF + EK+V +M IDLLRQQQKWKD+L +IRQI+ + Q EN PWK H D QLYKALE+QY +GLE LNENLPEIRV+L +RQ RLQF P EEIK+KYF+EMKKFI +PN FKG+ D++ LIFP++I+RN GF+ CY+KA LF+RL KFK+W++LG LD+++FV QH +L D+E+NFKA+K +G++AEKLPNEIK+DCI V+ P+K +D IQ +FDALL SLRK I + ++ +LT +++ LS+RPQ++ EI EA H EF K + I D +E N LLR+VAG G+D ++ LQ +WDKFELMMES Q+M++EQI+VMK+N+ SR K ++Q + KF+ RW LKPG D LD G + CL AV+ I+++K E +EL + L+ DCEHF +E EF L E++ +D+ + + MW FEE+ GLQ+LAKEDW+SFRSRYY FEE+L+QW+EKL++ + TTMT+RLQ+EI+ YK+++P+LKW+RGE LSQDHW+E+FR+L+MP+ TLE LT I+ A+ II +A +K+LNQ+AQGEVTIREA+REL+LWGAGAVF L +Y DS ++I LIK+W+++++QVGDNQCLLQSLKDSPYY+ F+DKA++WE +LADLDE NLNQIQRKWVYLEPIFG+ ALPKE+ RF+RVD+DFR+IM+DV R+NRVLS+ G+K L+ M+DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQ+TNP+VI++HLKKLF GI+ V F++ QHI+ MKS+DGE+V L+++V I EVE WL L +EMK TL + L L+D + S G++ +KYPSQ+LCL EM+ FT RCEE + N++ + E+ ++L+ YTN M + D +V +LKLK+LILD +HNI++I+ L + + +W W KQLR+Y K V++MVDAEF+YTYEYQGNAPKLVHTPLTDKCYLTLTQ M +GLGGNPYGPAGTGKTESVKALG LFGRQVLVFNCDEGIDVKSMGRIFIGLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ+IQD IK + I LL R ++VD NS IFIT+NPAGKGYGGR KLPDNLKQLFRPVAMS+PDN+LI EVIL S+GFK+A+ LGRKLVAIFNLS+ELLTPQQHYDWGLRALKT+LKG +LL+ +K QG V +D E +L+VQALR+NTLSKLT++D I F+SL+KDVFP + K+IEY+ L ++EV E N++ + Q +K LE YEQ RQRMGVV+VGPSGSGKST+WK++R AL K+G+ V+ YVMNPKA+PRTQLLGHID+DTREWSDGVLTY+ARQVVKEP E+QSWI+CDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLS E TDVK+LV SWL K++E ++ LS +++D+FYK+L+W+ K+ + + TS VGTV NGLS+ +KNK HF+VCL++G+GGNL+E+ RE FA V+ E P+ + L+ ++++ +RL YS + ++ +I+ P+I TAD+QR ++ F WL + +QPFIL+GPEGCGK L+L HCF L+S QV T+HCSAQT+P H+LQKL+Q C+ I++NTGRVY+PK+ ERLILYLKD+NLPK DKWGTSQL +FLQQ++TY GFYDSNLEFVGLDGVQIV SM++ SS+GR L+TRFTS+VRLCSISYP +DQL IY +YL PVL R + KHP+WS SK+ LA+TM++VY Q+++KFTVDDY HYLFTP DLTQWVLSLLRYDL + +NT+ +LEI SYE+ R+F+DR+V + +R D IL + + S+WS + ++L ++VTWG+R A GK+LGKL E L+ I++GLLQYSRE RDLDI++F+EV +N+A++DRVLT PGGS+L+AG++GVGRRT LV+HMH + L++PK+ RGY +K FKNDLK+ +Q G+EGE VLLLEDHQFLEP +LELINSLL++GEVPGLY+ EELEP+L L+DLA+E+ RG+ +FA RI+ LHI LIM+C+N F +NC+SNPAF+K C+V W++ WSR SM+K+P +L+ + P+ EG+ L + + + +L+G D L FL +H++C + +T R Y+ F+ + +Y K I+ RQ H+ G+ K++EAKE+VA+L SKAAEQS++L EKQ EAD++LK+IT MQ A+++K EME L + EEN L KRK ID EL I+P V +A AV IK+ L EIRALRAPPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+IQTF+AR+IT E R VE++L++ SF+PKNAKRAS AAAPLAAWVKANVK+SY LE+I PLE+EQ +L++NL+ AE +M+ L + + +VD+ V G ++ FEK T +AAKL++EL+ A ETI+AAE+LV KL+ E+ERWN Q+ EL+ EL+ L +K+LLA+A + YM S+PED R + ++ W + G+ FD+R+FL+TE EQL WK EGL SD+LSMENALVILQ L PFLIDPSS AT WLK H K+ +LE++NQQD+NFST LEL+VRFGKTLIIQE+DG+EP+LYPLLRGDLI+QGPR VVQ+G+K IDYN +F+LFLATRNP P++PPDA ++V+ VNFTTT+AGL GQLLA T+QH KP+LE RKT LL++EE LKI+L+K+EESLL+ELANA GNIL NK+LL SLN TK SSITIS SL ESV+LQ SLD ER A+LPLAE+GS LFF+ISDL KINNMYRFSL +FLRLFQRAL + + R SL + L LVYEYVCRS+FK+DRLMFALHM H PD+F+ EWE FTG +SD + + VP WI+ DR A+ + S P+L+S LN++D W QFA+SS+CE++ P L+ +LS FQ++L++QA RPDRLQSA+S F C L +K LSP ++NL ++++ ET ++EPILIIIS GADPSQ+L++L+ IGSE+Y QVAMGQGQA+I L LLH+CS+NG+WLCLKNLHLVT+WLP LEKE+NSL+PH+DFRLW+TAE H F TILLQSSLKITYEAPPG+K NL+R+Y++WS +F+SK GS R+ A+F+LAWFHA++QERRN+IPQGWTKFYEF ++DLR+G EI+D++ ++ R IQW F+HGLFE AI+GGRVDNPFD RV+ SY+ ++F+ ++++ GN G +Q+P++ RDY+ I L +++ P++F LP+NI+RSSQRIISS V+ LRIL+R V +KFDKD+W+ EL P+LN WK LNQGLN+I++ + +S TD PV +FL LER+N+I+ V+ +H+SL +LSKV++G++LLT EVQ L+ L+ +TP WL +W GPE+P Y+R LI +A AV +W E E LL+ LDLG LFHPDTFLNA+RQ TAR K SMD LKFV W GS A ++KIGNL +EGC FDGT ++E RDS S+ +P +V ++ KN P YS +++IS+PIYY I RD IVT++D+PC G +W+Q G ALFLKS
Sbjct: 5 DSRKEFILATTGNYFGLQVNEPAVSACHNSKDLNCFLDDGGTGVLVGMLENKKIAFSTQISTSAKDDKLIVFFKTKPEAITPDNLHSTVFVSTMLDSPVTALYHAVQKVYAPILLKDEKWSKNFDPKLQSLLTELEAGLGSVMRKQDASFRGPASDGNEDSLGGILTPADEFQYWAESALAGAKS-SKERAQHFNEILQPITREFLALESQNLQEVLELVEVTQDTLDDLWKQTECEPTYPQPRMKHLLNVIAGAFGRYVQHQLADLDLWKGPYGQVKQRLRSGLMICERWISACHTLTSQFWKRYGPNPWKGDKCTPEGMVQLAQ-RLEEIITLRSVHEQLVRLLDHQDQQDLGVKQAFAPFGGLLPLQHNPYTQPLWNAAVAQYDRAMAPAEKRIANKLRNQFNALEGNS--QQLLREFQRYKDLVKRPSLSEELATERRVLLTVLL---RQTRDDFLQRTSSGAAKGIPKGKNLPESVNNIVWVRQMEAKVEETMKTAEALLGDLPGFKSFRKDASDLLEELSSWRQDTFDEWSRDVQSQMEDQ-NNAICLETNGRLMELNHRDGKLYVNYGDRLVTLLREVRSLTALGYSIPSKILRAAETGNKFYRHGVILKQVAHFYNSIDQQMIPSQQSMMLESALAFERIIKNPKAGHKSKGDGVQVTWDRPDELELYIEKVQSAANRLTSENRRLRKCHFTVAEKVVQMMAIDLLRQQQKWKDSLMDIRQIMANLVQQGFSAENMRPWKSHWDRQLYKALEHQYQMGLEGLNENLPEIRVELTFRQQRLQFRPPLEEIKAKYFREMKKFIAIPNHFKGVGDAT--ENLIFPAIIDRNGVGFITCYKKAGDLFRRLERAAEKFKDWVVLGGLDIDKFVSQHLQNLPDWERNFKALKVRGRDAEKLPNEIKVDCIVVSTTPVKAVIDDHIQRLFDALLTSLRKGITNDFNRIEGFLTQAMETLSQRPQSVQEIGEANAKHGEFTKQKKEILPLFDAAESKNKLLRSVAGAGVDQLNTLQGRWDKFELMMESHQLMVKEQIDVMKSNVESRIKNYEQTLEKFSARWHQLKPGDDALD-GDQEKCLQAVKSIRERKQEFDELDASREALKTDCEHFDLEFPEFELAEDLREDLSKYESMWGLFEEFNNGLQDLAKEDWISFRSRYYQFEEYLSQWYEKLKSDQPTTMTVRLQQEIEKYKNVLPVLKWVRGEPLSQDHWMELFRMLHMPKTTTLEKLTFGQIIAASDHIIANATQLKDLNQRAQGEVTIREALRELDLWGAGAVFALTDYEDSHKHTIMLIKDWKELVNQVGDNQCLLQSLKDSPYYKSFEDKASIWEVRLADLDEIFLNLNQIQRKWVYLEPIFGRGALPKEQGRFKRVDDDFRAIMADVRRDNRVLSIVGKHGLKGQLTQMLDQLQRCQKSLNEFLEEKRSQFPRFYFIGDDDLLEILGQATNPEVIQTHLKKLFAGIHSVQFDEGTQHIVAMKSVDGEIVPLKHKVQIQPEVEVWLSRLADEMKGTLKELLKDCLRDAK----STQGLDPNKYPSQVLCLGEMVQFTERCEEAMKTNSLNSFHGEMQQQLDSYTNVDMGGGSGAPGAEKDPAVVVLELKLKALILDCIHNIEVIEILEKNGVRDIIQWLWQKQLRYYM-GKGSSAVMRMVDAEFDYTYEYQGNAPKLVHTPLTDKCYLTLTQAMAIGLGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQVIQDAIKARAPSIDLLNRAIDVDPNSGIFITMNPAGKGYGGRSKLPDNLKQLFRPVAMSKPDNELIGEVILFSEGFKDARNLGRKLVAIFNLSKELLTPQQHYDWGLRALKTILKGCGSLLQ--NTKQSAQGK-----VSSTD-EARLVVQALRINTLSKLTFSDSIAFDSLVKDVFPGVPFKDIEYETLREKLKEVCAESNLMVNETQIRKCLEFYEQTRQRMGVVVVGPSGSGKSTLWKIMRQALAKVGKVVRQYVMNPKAMPRTQLLGHIDMDTREWSDGVLTYAARQVVKEPVEVQSWIVCDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSDEDTDVKALVNSWLMKKEERERDSLSGWIEDYFYKALEWVLKQGDLVVDTSLVGTVMNGLSHFHNVKNKTHFAVCLVRGIGGNLSESCRENFAKEVFSWVGEHLPDPRRP--LDVTYDDEYSRLTGYSNQMSDQPTIEDFTGSN---LPVIRTADVQRFIESFASWLQPENRQPFILNGPEGCGKGLLLQHCFDSLRSSQVATIHCSAQTSPSHILQKLSQTCMTISTNTGRVYKPKDCERLILYLKDLNLPKPDKWGTSQLTAFLQQLLTYNGFYDSNLEFVGLDGVQIVASMSAGSSLGRHKLTTRFTSVVRLCSISYPDRDQLQAIYASYLTPVLARQLSKHPVWSSASKINALASTMVQVYEQVRAKFTVDDYGHYLFTPRDLTQWVLSLLRYDLAAGANENTSDQVLEIWSYEAHRLFRDRIVGPENIERFDSILMSVVRSDWSGNIFEALQSAFYVTWGARADAGVSATGIGAPLPPHGKALGKLGGEDLQKVIEKGLLQYSRENRDLDIVVFREVLENIARVDRVLTMPGGSLLMAGRTGVGRRTAVTLVAHMHQMTLVTPKISRGYGVKNFKNDLKTAMQLTGIEGEQAVLLLEDHQFLEPSFLELINSLLSAGEVPGLYSPEELEPLLAPLRDLASEANFRGTTMQFFASRIRTNLHIALIMECTNTKFSMNCESNPAFYKQCAVLWMDSWSRQSMVKVPQLLLTRPPKVEGASLGEKKQRQR-KLSGGDELLKGFLHIHESCDTITDVATPRRYMAFVHAFNEVYNNNKKGIQDRQTHLNAGVAKLNEAKELVADLNSKAAEQSRVLAEKQEEADQSLKEITFTMQSASDQKSEMETLKKQAAEENKKLEKRKVEIDKELREIQPLVDEASAAVGAIKNETLGEIRALRAPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVKEDIQTFEARKITPEIRDGVEKMLSKNGASFEPKNAKRASQAAAPLAAWVKANVKFSYVLERIEPLESEQAKLQKNLQKAESRMEKLGRALDEVDRKVEGLKRKFEKTTTEAAKLKYELEKAQETIAAAENLVGKLQGEYERWNGQVGELSQELTELPLKALLASAFITYMSSAPEDVRHQCLEAWKDFVGVRTFDLRRFLSTESEQLIWKGEGLPSDDLSMENALVILQTSLRPFLIDPSSRATDWLKVHLKENRLEVINQQDANFSTALELAVRFGKTLIIQEMDGVEPILYPLLRGDLIAQGPRFVVQIGEKTIDYNEEFRLFLATRNPAPEIPPDAASVVTEVNFTTTRAGLSGQLLAQTIQHEKPQLEVRKTELLKQEEDLKIQLAKLEESLLEELANAKGNILENKELLASLNLTKASSITISDSLTESVRLQTSLDHERSAYLPLAENGSKLFFIISDLCKINNMYRFSLAAFLRLFQRALQGKQEGSSPEHRIKSLNSALLYLVYEYVCRSLFKADRLMFALHMVHSMFPDMFQENEWEAFTGMIVSDVKNEGRSAGQVPNWIEPDRAQAVLLIQSTFPKLFSDLNLQDSSQWSQFARSSQCEQDFPGPLQRQLSAFQQLLVVQATRPDRLQSAMSLFACQTLGMKELSPPNVNLKRLFQKETTASEPILIIISAGADPSQELEDLAKGTIGSEKYRQVAMGQGQAEIALQLLHECSRNGEWLCLKNLHLVTAWLPSLEKEINSLQPHEDFRLWMTAEVHPKFPTILLQSSLKITYEAPPGIKKNLMRTYESWSPEFVSKGGSVARSQAMFALAWFHAVMQERRNYIPQGWTKFYEFGMSDLRSGAEIIDRLCSRAGRGQIQWDFVHGLFEFAIYGGRVDNPFDNRVMVSYLTQFFDPTILSEQSRGNKRLGPLQVPNSTMSRDYIEAIEALPEFDKPAYFGLPENIERSSQRIISSAVVSTLRILKRADVKASKFDKDVWANELGPILNVWKKLNQGLNLIQSKVSPPSDKSGTDPPVKSFLLLERFNAIRTVQSIHASLAALSKVIRGTQLLTSEVQLLASALMNQETPQSWLSKWSGPEDPMLYLRGLIGRAVAVSRWVEKVESRSLLNETLDLGHLFHPDTFLNAVRQQTARESKCSMDSLKFVASWKGSIQGASLNIKIGNLQLEGCSFDGTRLSENQRDSPSVSEIPTCNVAFIPKNAPEPYSANEVISIPIYYSIERDNIVTRMDVPC-GGNHLQWLQCGAALFLKS 4308
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. TrEMBL
Match: V4AES5 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_209197 PE=4 SV=1) HSP 1 Score: 4955.96 bits (12854), Expect = 0.000e+0 Identity = 2449/4331 (56.55%), Postives = 3212/4331 (74.16%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHFP---NQN--SKFVNEECLDKFFDNLDNNVLVVKFIDNK----FIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHR--SRQGK-VPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKN---VVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPV-TSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXX-----KSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTC-PVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQ-------GILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNF--YGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RK + ++F N N N L+ F D+ + +VL DNK F SN++ + + N +VF KT P ++ PDNI+ +IV+++ ++P+S+LY+ +Q +Y PILL D DPK+Q L+SELE GLGS IR+ E + I S DE +W+D ++ S +++ R + + ++++ + + + +E L+DIW+ +P+YP++RMK LM++I L R Q +L+ W ++ ++E+L + +C W+ +C+ L ++W++Y PH W + + I RL EI SLRTVHE I ++L E+++ ++ +AF FL + PL YNPYT+P+W AV ++ R + PAE I +L+ F+ PQQLLR FQRY LI RP I + ERETLL QL ++ +Q+ EDF R R GK +P KN D ++ I++ +QLEAK+ E + +L DL GF+KF K + EE+ +WR++QF++W+++M +DD I L+ GRLMEL+ KDG L VNYS+RLV L+REVR LS +G+ +S + A+ GQKFY V+LKQVA FYNTI+ QMI QQAMMLD+A+ FEKLVK+ S +K K V W+NPEEL +I KLQ A+ + ++NR LRK HF++ +K+ LMGIDLLR Q KWKD L EIRQ++ + Q +N PWK H DHQLYKALE+QY +GLEALNENLPEIRV+L YRQ RLQF P FEEIK+KY++EMKKFI++PN F+G+ +++ +I+ ++I+RNA GF+ CY+K LF RL + +++FK+WIILGSLDL++FV+ + D+ +EKNFKA+K +G++AEKLP++IK+DCITVN P+K +D IQ +FDALLNSLR++I + S+D +L +++ LSKRPQ ++EI EA HAEFN + I+ K+E N LLR+VAGGG++T+SQLQ +WDKFELMMES Q+M++EQ+EVMK N+ SR K + QDI KF+ RW LKPG D LD G C A+ IK+K+ E EL + L DC+HF +E +F +EE+ DI + MW +E + GLQ LAKEDW+SFRS+ YLFEEFL W+EKL+N E TTMT++L K+I+ YK ++P+LKW+RGE LSQDHWLE+FRLL+MP+G TLE L I+ + +II +A+A+KELNQ+AQGEVTIREAIRELELWGA A F L EY DS N+I LIK+W+D+++QVGDNQ LLQSLKDSPY++ F+DKA+VWE +LADLDEYL NLNQIQRKWVYLEPIFG+ ALPKE+ RF+RVD+DFRSIM DV R+ RVLSL + SG++NLLSTM+DQLQRCQK+LNE+LEEKRSLFPRFYFIGDDDLLEILGQSTNP VI++HLKKLF GI+ V+F++ +HI+ MKSLDGEVV L ++ I EVE+WL L +EMK TL + L L+D + S G++ +KYPSQILCL+E I FT CEE + NN+ +EL +L YT+ MS D V +LKLK+LILDT+H+ID++ +L+ N + +EW W+KQLR + KD CV++MVDAEF YTYEYQGNA KLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKA+G LFGRQVLVFNCDEGIDVKSMGRIFIGLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ+IQD IKNKV I LL + ++++ NS IFIT+NPAGKGYGGRQKLPDNLKQLFRPVAMS+PDN+ IAEVIL S+GFK AK +G KLVAIFNLSRELLTPQQHYDWGLRALKTVL+G NLL+ K + N D E KL+VQALR+NTLSKLT++DGI F+SL++DVFP I+ K+IEY++LA A+ EV KE N+ + Q KK LE+YEQLRQRMGVV+VGPSGSGK+T+W++LR ALNK GQ VK YVMNPKA+PRTQLLGHID+DTREW+DGVLTYSARQV+KEPQE+QSWI+CDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E DVK+LV SWL Q E +QHL+S +++D+FY++LDW+ K+N+F + TS VG V NGLS+L IKNKAHF++CLI GLG N++E+ RE FA V+ E PE + L+ Y++E RL+TYS E E L+ D + P+I T+D+QR+LDYF WL+ D +QPFIL GPEGCGK L+L H F+ L+S Q+ +HCSAQT P H+LQKL+Q C+ I+SNTGR+ RPK+ ERL+LYLKDINLPK DKWGT Q+ISFLQQVI Y GFY S LE+VGL+ +QIV SMN+ +++GR L+TRFTSIVR+C + YP +QL IY++YLKP+L + + HP+W +SK+ LA TM++ Y QL+SKFTVDDY HYLF P DLT WVL+LLRYDL ++NT ++L I +YE+ R+F+D++V + R R D +L + + ++WS + D L ++VTWG+R A A K LG L+S+ LK I++G+ Y RE R+LD+++FKEV +N+A++DRVLTKPGGS+L+AG+SGVGRR+ +V++MH ++ SPK RGY LKQFKNDLK+ +Q++G++G +V++LEDHQF+EPQ+LELINSLL++GEVPGLY+ EELEP+L L+D+A+E G RG++ NYFA RI LHI+L+MD +N F +NC+SNPAF+K CSVQW++ WSR+SM+K+PYML+ + P+ EG + + + + +L+G + L FL +H++C PV T R ++ F+ Y ++Y +KK+ IE RQ+H+Q G+ K+++AK +V ELKSKAAEQS L EKQ EADKAL +IT MQ A ++K EME L + EEN L KRK AID EL+ IEP V++ R AV +IK+ LSEIR+LRAPPDVIRDILEGVL +MG DTSWVSM++FL KRG++EEIQTFDAR+I+ E R VE+LL + SFDPKNA+RAS+ A PLAAWV+ANVKYSY LEKI PLE+EQ L++NLE AE KM+ L + + +VD VA R FE FT +AA+L+ +L NETI AAE LV KL+ E++RWN Q+ EL+ EL+AL +LLAA + Y+ S+PED R+ ++ WM+ G+E F++R+FL+TE EQL WK EGL SDELSMENALVILQ L PFL+DPSS AT WLKNH KD +LE+VNQQD+NF+T LEL+VRFGKTLIIQE+D +EPVLYPLLRGDL +QGPR VVQ+G+K IDYN +F+LFL TRNP P++PPDA ++++ VNFTTT+AGL GQLLA+T+QH KP+LE +KT+LL++EE LKI+L+K+E+SLL+ELANA GNIL NK+LL SLN TK SSITIS SL ESV+LQ SLD+ER+ +LPLAE+GS L+FVISDL+KINNMYRFSL SFLR+FQRAL+T + + MR +L L+ ++YEYVC+S+FK+DRLMFA+HM H +P++F EWE FTG ++D P W+D +R A++ + P+L++ +N+ D W FA+SS+CE E P S++ +++ FQ++L+IQA+RPDRLQ+A+S F C +LE+K LS ++NL ++Y+ E+IS EPIL+IISPG DPSQ+LQEL+ + +G +RY+QVAMGQGQ+++ + LLH+C+ G+WLCLKN+HLVT+WL LEKELNSLKPH DFRLW+T E H F TILLQSS K+TYEAPPGVK NLLRSY+ W+ ++IS+ GS R+ ALF+L WFHA++QERR +IPQGWTKFYEFS++DLRAG I+D++ + ++QW+FIHGLFE AI+GGRVDNPFDMRV+ SY+K++F+ SV++ G G +++PS+ S +DY+ I L +++ PS+F LP+NI+RS+QRIISS VI QLRILQR V +KFDK++W+ EL P+LN WK LNQG N+I+ L ++ SP+V+F+ LERYNSI+LV+ VH+SL LSKV++GS+LLT + QNL+ LL +TP WL+ W+GPE+P Y+R L+ +A++++ W E +E LL LDL ELFHPDTFLNALRQ TAR I SMD LKF C W GS A YS+K+G L +EGC FDG+ ++E RDS S+ +P V W+ P+ YS DD +S+PIYY RD IV K+D+PC G Q W+Q G ALFLK+
Sbjct: 4 DSRKQFLLATAANYFSLPINDNVLGSLQNSSALNSFLDDGNCSVLSAS-KDNKSGQSFQLSNKVESGESKDNVIVFFKTKPDVLNPDNIHKNVIVSSMVDSPLSTLYHAVQKVYAPILLEDGRWSRGLDPKLQSLLSELEAGLGSTIRRTDPSFRGKDGSEDNLGNILSPMDEFNYWSD-VAHSGRGESKDRAQCFLDLFKPISKDYGGLETMPFQDVMELVEITQDTLDDIWKQGDYDPSYPENRMKHLMDVIGGSLARYCQKKLSEEDLWNGVFSPIREALRSGLTICERWVSVCETLTLQFWRRYAPHSWKGEKFVP-ENIKKLGERLEEILSLRTVHEHILRLLSSSEQKDLQVTDAFTPFLGLNPLQYNPYTKPLWDAAVAQYERAMGPAEQKIAAKLRGQFRGLDG--YPQQLLREFQRYKALIKRPTIRREMASERETLLGQLTVYVRQISEDFNARIGGRGGKSIPKGKNLPDIVNNIIYVRQLEAKIEETNLVAEMLLGDLTGFQKFRKSASDLSEELQSWRRDQFDEWSRDMQSMIDDPKQP-ISLETNGRLMELNHKDGKLRVNYSERLVTLLREVRQLSAIGFAVSAKIQHVANVGQKFYRHGVVLKQVAHFYNTIDNQMIASQQAMMLDSAMAFEKLVKNPKSGNKAKGDDVQVTWDNPEELESYIKKLQAAADRLTTENRRLRKSHFVVSDKVQQLMGIDLLRHQSKWKDGLMEIRQLMANLVQQGFSADNMRPWKLHWDHQLYKALEHQYQMGLEALNENLPEIRVELTYRQQRLQFRPPFEEIKAKYYREMKKFISIPNNFRGVTETT--GSVIYTAIIDRNAEGFITCYKKGNQLFDRLGSVIHQFKDWIILGSLDLDKFVEDNLTDIHQWEKNFKALKVRGRDAEKLPSQIKVDCITVNTTPVKAVIDDHIQRLFDALLNSLRRSIVSEVGSIDTFLNTAMETLSKRPQTVEEIGEANAKHAEFNATKKEIQPLFQKAEAKNKLLRSVAGGGVETISQLQGRWDKFELMMESHQLMVKEQVEVMKKNVDSRVKTYHQDIEKFSARWHQLKPGDDALD-GDKAKCDHAMNVIKEKREEFAELEATRATLLSDCQHFGLEEPDFGAVEELRNDIKNYESMWGLYENFNNGLQELAKEDWISFRSKAYLFEEFLGGWYEKLKNEETTTMTVKLHKDIEKYKTVLPVLKWVRGEPLSQDHWLELFRLLHMPKGTTLEKLNFGQIIAVSDQIIINADALKELNQRAQGEVTIREAIRELELWGADATFSLTEYEDSNKNNIMLIKDWKDLVNQVGDNQSLLQSLKDSPYFKSFEDKASVWEQRLADLDEYLHNLNQIQRKWVYLEPIFGRGALPKEQGRFKRVDDDFRSIMQDVRRDTRVLSLVNQSGLRNLLSTMLDQLQRCQKSLNEFLEEKRSLFPRFYFIGDDDLLEILGQSTNPNVIQTHLKKLFAGIHSVEFDEASEHILAMKSLDGEVVPLIRKIKIVPEVESWLSKLADEMKDTLKELLLNCLKD---AKSSRGGLDPNKYPSQILCLAEAIRFTQNCEEAIQSNNLRVYLQELEGQLESYTSVDMSAGQDVEAKVLELKLKALILDTIHSIDVVRELMTANIRKTSEWLWMKQLRVNMR-KDGVCVLRMVDAEFEYTYEYQGNAQKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKAMGGLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQVIQDAIKNKVSRIDLLGKNIDINHNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSKPDNEQIAEVILFSEGFKQAKSVGSKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGCGNLLQTTKKAL---------NGVDGKTEAKLVVQALRINTLSKLTFSDGIRFDSLLRDVFPGIEFKDIEYEDLAEAMREVCKETNLSINEKQIKKALELYEQLRQRMGVVVVGPSGSGKTTLWRMLRQALNKRGQVVKQYVMNPKAMPRTQLLGHIDMDTREWTDGVLTYSARQVIKEPQEVQSWIVCDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSCASPATISRMGMIFLSDEDVDVKALVKSWLSTQPESEQHLISGWIEDYFYRALDWVLKQNDFVVETSLVGCVLNGLSHLHNIKNKAHFAICLIHGLGSNISEHHREKFAQEVFSWVGEAPPESRRP--LDAYYDESVGRLMTYSTEVPENLTADHFTISSNL--PVIRTSDVQRSLDYFTPWLDPDNKQPFILVGPEGCGKGLLLRHSFEHLRSTQIAVVHCSAQTNPSHILQKLSQTCMEISSNTGRLLRPKDCERLVLYLKDINLPKPDKWGTCQMISFLQQVIIYNGFYSSTLEWVGLENIQIVASMNAVTTLGRHKLTTRFTSIVRICVVGYPDHEQLQTIYSSYLKPILHKQLAHHPVWGSSSKINTLAGTMVQFYEQLRSKFTVDDYGHYLFAPRDLTSWVLNLLRYDLSSGANENTCDTVLRIWAYEAQRLFRDKIVGLEGRNRFDNMLMSAVRADWSTNIFDELASTFYVTWGARTDSGAPAVAAGAPLPIFGKPLGLLSSDDLKQVIEKGIRIYGRENRELDLLIFKEVLENMARVDRVLTKPGGSLLMAGRSGVGRRSAVAVVANMHQMEFFSPKTSRGYGLKQFKNDLKTVMQSSGIDGNQVVMVLEDHQFVEPQFLELINSLLSAGEVPGLYSPEELEPLLAPLRDMASEVGFRGTMVNYFASRIMSNLHIVLVMDNTNTLFTLNCESNPAFYKQCSVQWMDGWSRESMVKVPYMLLTRPPKIEGGSIGEQKQRQR-KLSGGEELLKSFLHVHESCDPVNL-TPRRFMVFLNTYQQVYNEKKSSIEKRQHHLQAGVSKLNDAKHLVDELKSKAAEQSIQLAEKQREADKALSEITVSMQNAGDQKNEMEVLKQQAAEENKKLEKRKVAIDQELSEIEPLVQETRKAVGNIKTESLSEIRSLRAPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVKEEIQTFDARKISSEIRKSVEDLLRKNGASFDPKNARRASVVAEPLAAWVRANVKYSYVLEKIEPLESEQAMLRKNLEKAESKMERLGRDLDEVDNKVAQLRARFENFTKEAAELKIKLDKENETIQAAETLVSKLDVEYDRWNAQVGELSNELNALPKLALLAAGFITYLSSAPEDVRRSTIKGWMDAIGVESFEIRRFLSTESEQLIWKSEGLPSDELSMENALVILQVNNLPVGSSLRPFLVDPSSRATEWLKNHLKDSRLEVVNQQDANFNTALELAVRFGKTLIIQEIDQIEPVLYPLLRGDLTAQGPRFVVQIGEKTIDYNEEFRLFLTTRNPSPEIPPDAASVITEVNFTTTRAGLTGQLLAVTIQHEKPELEVKKTDLLKQEEDLKIKLAKLEDSLLEELANAKGNILENKELLDSLNMTKASSITISDSLTESVRLQSSLDQERNTYLPLAENGSCLYFVISDLAKINNMYRFSLASFLRIFQRALHTQHDGSGTEMRIKNLSYRLQLMIYEYVCQSLFKADRLMFAMHMVHGMKPNMFAENEWEAFTGILVADVKAEG-GRPNWVDEERGQAVAAFKTNFPQLYNQMNLDDGSTWSNFARSSQCELEFPSSIEKRITPFQQVLLIQAVRPDRLQTAMSHFACSLLEMKELSLPTVNLKKLYQ-ESISTEPILVIISPGVDPSQELQELAVETVGMDRYHQVAMGQGQSEVAMQLLHECAVKGEWLCLKNIHLVTAWLQTLEKELNSLKPHDDFRLWLTTEVHPRFPTILLQSSHKVTYEAPPGVKKNLLRSYETWTPEYISRGGSVIRSQALFALTWFHAVVQERRMYIPQGWTKFYEFSLSDLRAGANIIDRLCSGAGHDVQWQFIHGLFEFAIYGGRVDNPFDMRVMVSYLKQFFDASVLSSQGKSKRVGPLKIPSSTSYKDYIEAIEALPEFDKPSYFGLPENIERSAQRIISSAVISQLRILQRADVKASKFDKEVWANELGPILNLWKKLNQGSNLIQQKLTPPSDKTGKQSPIVSFILLERYNSIRLVQTVHTSLSGLSKVIRGSQLLTSDTQNLAAALLNQETPISWLKSWDGPEDPVQYLRGLVNRAQSMQSWVERAEGGSLLRDTLDLSELFHPDTFLNALRQQTAREIGCSMDSLKFACSWKGSIQGANYSIKLGGLQLEGCSFDGSRMSENQRDSPSVSAIPSCQVAWIPAELPDPYSVDDTMSIPIYYSSTRDHIVAKLDLPC-GGNQSTWLQCGAALFLKN 4303
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. TrEMBL
Match: A0A1S3JIZ4 (cytoplasmic dynein 2 heavy chain 1 OS=Lingula unguis OX=7574 GN=LOC106173688 PE=4 SV=1) HSP 1 Score: 4948.64 bits (12835), Expect = 0.000e+0 Identity = 2463/4337 (56.79%), Postives = 3220/4337 (74.24%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHF---PNQNS--KFVNEECLDKFFDNLDNNVLVVKFIDNK-----FIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQ--TDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPT-KNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKN---VVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLS-ADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXX-----XKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPV-EFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQ-------GILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFI----SDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGS---GNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RKD I T ++F P S N L+ F D+ + N+L + I+ K F N++ +D +VF K P +ITPDNI+ + V+++ ++P+S+LY+ +Q ++ P+LL D DPK+Q L+SELE GLGS+IRK + S Q TDE + GI + DE FW++ + + + R Q ++++ + S +L E +E L+++W+ +P Y +SRM+ LM++I L R IQ +L W+ ++ VKE L + VC W C+ L ++WK+Y PH W D + ++ RL EI++LRTVHEQ+ ++L +E++E + AF F + PL YNPYT+P+WK AV ++ R + PAE I +L+ F+ + QQLLR FQRY +LI RP IS ++ ERETLL QL + KQ+R+DF R+ K PP KN + ++ IVW +QLEAK+ E I +L DL GF F K+ + L+E+ +WRQ+QF++W+++M +++DS + L+ G+LMELS DG L+VNYS+RLV L+REVR LS LG+ I + A QKFY AVILKQVA FYNTI+ QMIP QQ+MML++A+ FEK++K+ S +K K + W+NPEEL +I KLQ A+ + S+NR LRK H ++CEK+V LM DLLR QQ+WKD L +IR ++ + Q N PWK H D QLYKALE+QY +GLEALNENLPEI V+L YRQ RLQF P FEEIK+KYF+EMKKFI +PN FKG+ D++ LIFP++I+RNA GF+ CY+KA LF+RL+A FK+W++ G +DL++FV + ++L D+E+NFKA+K +G++AEKLP++IK+DCITVN P+K S+D IQ +FDALL+SLRK I I ++D +LT +++ L++RPQ ++EI A H+EF K + I+ K E N LLRTVAGGG++ LQ +WDKFELMMESFQ+M++EQ+EVMK+N+ SR K F+Q++ KF RW LKPG D LD G Q C+ AV+ IK++K+E EL L+ DCEHF ME EF EI +D+++ + MW +EE+ GLQ L KEDW+SFRS+ Y+FEEFL W+EKL++ E TTMT+RLQK+ID YK+++P+LKW+RGE LSQDHWLE+FR+L MP+G TLE L IL ++ II +A A+KELNQ+AQGEVTIREAIREL+LWGAGAVF L +Y DS +N I LIK+W+D+++ VGDNQCLLQSLKDSPYY+ F+DKA VWE +LADLDEYL NLNQIQRKWVYLEPIFG+ ALPKE+ RF+RVD+DFR+IM DV R+NRVLSL G++N L TM+DQLQRCQK+LNE+LEEKRS+FPRFYFIGDDDLLEILGQ+TNP+VI++HLKKLF GI+ V+F+ +HI+ MKSL+GEVV L+ +V IT EVE WLG L EMK TL L+ L+D + Q G++ +KYPSQILC +E I+FT +CEE + +++ E+ KL YT +S + +D V +LKLK+LILDT+H+ID+I QL++ +++ +W+W KQLR+Y + +D CV++MVDAEF YTYEYQGNA KLVHTPLTDKCYLTLTQGMH+GLGGNPYGPAGTGKTESVKALG LFGRQVLVFNCDEGIDVKSMGRIFIGLVKCG+WGCFDEFNRLEEAVLSA+S+QIQIIQD IK K LL R V++D NS IFITLNPAGKGYGGRQKLPDNLKQLFRPVAM+RPDN+LIAEVIL S+GFK+AK LGRKLVA+FNLS+ELLTPQQHYDWGLRALKT+LKG NLL+ K ++ E + D+ E KL+VQALR+NTLSKLT++D I F SL+KDVFP + K+IEY+NLA AI EV KE+N+V + Q KK LE+YEQLRQRMGVV+VGPSGSGKST+W++L+ A+ K GQ VK Y MNPKAIPRTQLLGHID+DTREW+DGVLTYSARQVV+EPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TD+K+ +TSW+ E +Q L+ +++D+FYK +DW+ K+ +F + T+ VG V NGLS+L +++K HF+V LI+GLGGNL+E +RE FA V+ T E P+ + L+ Y++ RL++YS E ++L+ D S + P+I T DIQR LDYF WL+++ +QPFIL GPEGCGK ++L +CF++L+S Q+ T+HCSAQT P HVLQKLNQ+C++I++NTGRVYRPK+ ERL+L+LKD+NLPK DKWGTSQLI+FLQQV+TY GFYDSNLE+VGL+GVQIV SMN S++GR LSTRFTS+VR+C+I YP ++QL IY+AYLKPVL + + +HP+W +KV LA +M++VY QL+ KF+VDDYSHYLFTP DLT+WVL LLRYD+ + SD + +LE+ E+ R+F+D++V D R D IL + + +W V + + ++VTWG +A A P GK LGKL+ + K I +GLLQYSRE RDL++++FKEV D++A+LDR L+ PGGS+L+AG+SGVGRR+ L+S MH ++L SPK+ RGY LKQFK DLK+ +Q G++ E +VLLLED+Q + P +LELINSLL++GEVPGLYT EEL+P+L L+D A+E+G+RG L YFA RI+ LH++LIMDC+N NF +NCQSNPAF+K CSVQW++ WSR+SM+K+P++L+ + P+ EGS +++ + K +L+G D L FL +H++C V +T R Y++F+ Y+++Y KKN I RQ+H+Q G+ K++EAK MV +LK KAAEQSKLL EK EAD ALK+IT M A+E+K EME++ + EEN+ L +RK AID EL+ IEP V++A+ AV IK+ LSEIRALRAPPDVIRDILEGVL +MG D SW SM++FL KRG++EEIQ FDAR+IT + R VEELL + K+SFDPKNAKRAS AAAPLA+WV+ANVK+SY LEKI PLE EQ L++NLE AE K+ L+K +S+VD+ V R FEKFT +A L+ EL+ +TI AE+LV KL+ E+ RWN Q+ EL AEL L +++LLA+A + Y+ + PED R+ +Q WM+ G++ FDMR+FL+TE EQL WK EGL SD+LSMENALVILQ L PFL+DPSS AT WLK H K+ KLE+VNQQD NF T LEL+VRFGKTL+IQE+DG+EP+LYPLLRGDL+SQGPR VVQLG+K IDYN DF+LF+ TRNP P++PPDA +I+S VNFTTT+AGL GQLLA T+QH KP+LE RKT LL++EE KIEL+K+EESLL+ LAN+ GNIL +K+LL SLNKTK+SS+TI +SL ESV+LQ SLD+ER A+LPLAE+GS L+FVISDL+KINNMYRFSL +F RLFQRAL T + M+ +L L+ LVYEYVCRS+FK+DRLMFALHM H +P FK EWELFTG + +D S ++ +P W+D +R A+ L S P+L+ LN +D DLW FA+SSECE+E P ++ K+SLFQ++L +QA RPDRLQSA+S F L LSP S+NL ++Y++ET+ EPILI+ISPGADPSQ+L+E++++VIG ++Y+QVAMGQGQADI L LLH C++NG+WLCLKNLHLVTSWLPVLEKE+N++ PH+DFRLW+TAE H F TILLQSSLKITYEAPPGVK NLLR+Y+NWS +FI++ + RA ALF+LAWFHA+ QERRN+IPQGWTKFYEFS +DLRAG++I+D++ K + W F+HGLFE AI+GGRVDN FD RV+ SY+K++F V++GS G G I+LPS RDYL I L +Y+ PS+F LP+NI+RS+Q+ +SS VI QL++++R +V G KFDK++W+ EL+PVLN W+ LNQG +I+ + ++S P+ +F+ LERYN+IKLV+ +H SL +LSKV++G++LLT +VQ L+E LL +TP W ++WEGPE+P Y+ L+ +A A+++W + E LL+ LDL ELFHPDTFLNALRQ TAR IK SMD LKF W GS A+ S K+G L +EGC FDG ++E RDS S+ +PP V W+ K+ P+ Y +++I LPIY+ R+KIV ++IPC G Q +W+ SG ALFLK+
Sbjct: 5 DSRKDFILATTGNYFGISPADGSIADLHNSSELNSFLDDGNVNILAAR-IETKAGGKEVNFCNRVEPSDTNEKVIVFFKIKPDVITPDNIHRDVFVSSMLDSPVSALYHAVQKVFAPLLLKDEKWSKSFDPKLQSLLSELEAGLGSVIRKQDASYSGRQGDTDEDNLGGILTPSDEFQFWSEVAMSGAKLVIKERAQGFQEMFQPISKDFASLDSMALPECLELVELTQDTLDEVWKQTEHDPPYKESRMRHLMDVIGGALGRYIQRKLAQEDIWKGQFSKVKEKLRAGLSVCERWTSACETLTVQFWKRYGPHPWKGDKFVP-ENLTQLAARLEEITTLRTVHEQLVRLLSPQEQEELRTAAAFSSFAGLNPLQYNPYTQPLWKAAVAQYERAMAPAEQRIAGKLRSQFRSMQANS--QQLLREFQRYKELIKRPSISKEMVAERETLLGQLTVFIKQIRDDFTQRTSGDKAPPKGKNMPEVVNCIVWVRQLEAKVEETNIIAEALLGDLSGFHNFRKDLCDLLDELRSWRQDQFDEWSRDMQSQIEDSGKP-LSLETSGQLMELSHSDGKLHVNYSERLVTLLREVRQLSSLGFAIPAKIQHTAATAQKFYHHAVILKQVAHFYNTIDQQMIPSQQSMMLESALAFEKIIKNPKSGAKVKGDSVQITWDNPEELESYIQKLQAAADRLTSENRRLRKSHNIVCEKVVQLMSTDLLRHQQRWKDGLMDIRHLMANLVQQGFSASNMTPWKAHWDRQLYKALEHQYQMGLEALNENLPEIVVELTYRQQRLQFKPPFEEIKAKYFREMKKFIGIPNHFKGVGDAT--EHLIFPTIIDRNADGFITCYKKAGLLFKRLAAVQEMFKDWVVCGGVDLDQFVYDNLVELRDWEQNFKALKIRGRDAEKLPSQIKVDCITVNTNPVKSSIDDHIQRLFDALLSSLRKAIHNDISTIDTFLTTAMETLAQRPQTVEEIGTANAKHSEFAKQKKEIQPLFSKGESKNKLLRTVAGGGVEQFGNLQARWDKFELMMESFQLMVKEQVEVMKSNVESRIKAFEQELEKFGSRWHQLKPGDDALD-GDQQKCMAAVESIKERKVEFTELENTMKTLQTDCEHFDMEMPEFPYAAEIAEDVNKYESMWGLYEEFNNGLQELCKEDWISFRSKAYMFEEFLAGWYEKLKSEEPTTMTVRLQKDIDKYKNVLPVLKWVRGEPLSQDHWLELFRMLGMPKGTTLEKLNFGDILSSSDAIIINATALKELNQRAQGEVTIREAIRELDLWGAGAVFALTDYQDSGSNKIMLIKDWKDLVNAVGDNQCLLQSLKDSPYYKSFEDKATVWETRLADLDEYLHNLNQIQRKWVYLEPIFGRGALPKEQGRFKRVDDDFRAIMYDVARDNRVLSLVGKVGLRNQLVTMLDQLQRCQKSLNEFLEEKRSIFPRFYFIGDDDLLEILGQATNPEVIQTHLKKLFAGIHSVNFDDGCKHIVAMKSLEGEVVPLKKKVQITPEVEVWLGYLAEEMKNTLKQLLTECLKDSKAGGQG--GLDPNKYPSQILCAAEQINFTEQCEEAIKTSSLQEFNIEMENKLESYTGVDLSAAGSDVGVYVLELKLKALILDTIHSIDVIQQLVEAKTRNLEDWQWQKQLRYYTR-RDGICVMRMVDAEFEYTYEYQGNAAKLVHTPLTDKCYLTLTQGMHLGLGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGAWGCFDEFNRLEEAVLSAISIQIQIIQDAIKEKKPTAELLGRNVDIDFNSGIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMARPDNELIAEVILFSEGFKHAKSLGRKLVAVFNLSKELLTPQQHYDWGLRALKTILKGCGNLLQTAKKNLQEG-----EKITDA-IEAKLVVQALRINTLSKLTFSDSIRFNSLLKDVFPGTEFKDIEYENLAQAIREVCKERNLVVNESQVKKALELYEQLRQRMGVVVVGPSGSGKSTLWRVLKEAMLKCGQVVKQYTMNPKAIPRTQLLGHIDMDTREWTDGVLTYSARQVVREPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSCASPATISRMGMIFLSDEDTDIKAFITSWMNTLPEAEQKTLAAWIEDYFYKGMDWVLKQGDFVVETTLVGVVMNGLSHLHGVQDKTHFAVSLIRGLGGNLSEATREAFAKEVFAWTHETPPDPRRP--LDTYYDPSSGRLMSYSVELRDDLTADNFTSSANL--PVIKTGDIQRGLDYFAPWLSAENKQPFILVGPEGCGKGMLLKYCFEQLRSTQIATVHCSAQTNPTHVLQKLNQSCMVISTNTGRVYRPKDCERLVLFLKDLNLPKPDKWGTSQLIAFLQQVLTYNGFYDSNLEWVGLEGVQIVASMNGGSTLGRHQLSTRFTSVVRICAIGYPEREQLQAIYSAYLKPVLHKQLSRHPVWGNPAKVHALAGSMVQVYEQLRGKFSVDDYSHYLFTPRDLTRWVLGLLRYDM-IASDTSVNPVLEVWVNEARRLFRDKIVGVDGLSRFDNILMSAVQGDWGVSGMEGIEGNYYVTWGGHHDASAPAVAPGAPLPPTGKPLGKLSGDDFKSVIQKGLLQYSRENRDLNVIIFKEVLDHMARLDRALSTPGGSLLMAGRSGVGRRSAVTLISFMHQLELFSPKVARGYGLKQFKTDLKTVMQKTGIDDEQVVLLLEDNQLVHPAFLELINSLLSAGEVPGLYTPEELDPLLAPLRDTASEAGYRGPLHGYFASRIQANLHVVLIMDCTNANFSMNCQSNPAFYKQCSVQWMDGWSRESMVKLPHLLLTQGPKMEGSSMSEPKER-KRKLSGGDELLKSFLHIHESCEVFGTATPRRYVSFLHTYMQVYNNKKNVIAERQHHVQAGVSKLNEAKSMVDDLKHKAAEQSKLLAEKTTEADAALKEITERMSNASEQKTEMEQIKAQVAEENIKLEQRKKAIDIELSEIEPLVREAKAAVGSIKTEQLSEIRALRAPPDVIRDILEGVLKLMGINDMSWNSMKSFLAKRGVKEEIQQFDARKITPDYRKLVEELLDKRKESFDPKNAKRASAAAAPLASWVRANVKFSYVLEKIEPLETEQRHLQKNLEKAEAKLAKLQKALSEVDQEVERLRNRFEKFTREAEHLKIELEKEEKTIEDAENLVGKLDGEYRRWNDQVGELTAELGELPMRALLASAFISYLSAEPEDVRRNMLQQWMDMAGVKGFDMRRFLSTESEQLIWKGEGLPSDDLSMENALVILQINNIAAGSSLRPFLVDPSSRATEWLKVHLKEHKLEVVNQQDGNFITALELAVRFGKTLLIQEMDGIEPILYPLLRGDLLSQGPRFVVQLGEKTIDYNEDFRLFMTTRNPAPEIPPDAASIISEVNFTTTRAGLTGQLLAQTIQHEKPELEVRKTELLKQEEDFKIELAKLEESLLENLANSKGNILEDKELLDSLNKTKQSSMTIVESLSESVRLQASLDQERGAYLPLAENGSRLYFVISDLAKINNMYRFSLAAFFRLFQRALKTGQPGASPEMKVKTLNDSLQTLVYEYVCRSLFKADRLMFALHMVHGMKPQEFKENEWELFTGLLVADVKADHSKQSRDIPAWVDQERPQALLLLKSTFPDLYQQLNFQDTDLWSNFARSSECEKEFPSAIAKKISLFQQVLAVQATRPDRLQSAMSLFAVKALSRTELSPPSVNLKRLYQNETLPAEPILIVISPGADPSQELEEMASEVIGKDKYHQVAMGQGQADIALQLLHDCARNGEWLCLKNLHLVTSWLPVLEKEINTMTPHQDFRLWMTAEVHPKFPTILLQSSLKITYEAPPGVKKNLLRTYENWSPEFITRGNNTVRAQALFALAWFHAVCQERRNYIPQGWTKFYEFSSSDLRAGSDIIDRLCNKGKGEVAWNFVHGLFEFAIYGGRVDNQFDNRVMVSYLKQFFEGGVLSGSSSKGKKLGPIKLPSTTHYRDYLDAIEGLPEYDKPSYFGLPENIERSAQKQVSSLVISQLKVVKRATVKGNKFDKEVWAHELSPVLNLWRKLNQGSQLIQMKITAPSEKSDHAMPISSFILLERYNAIKLVQSIHQSLAALSKVIRGTQLLTTDVQKLAEALLNQETPMEWQKKWEGPEDPIQYLHSLVARAMAIQEWVQKVETKMLLNETLDLSELFHPDTFLNALRQQTAREIKCSMDSLKFAASWKGSVQGARLSAKLGGLLLEGCTFDGQRLSENQRDSPSVSSVPPCVVAWIPKDSPDPYPPNEVIPLPIYFSSDREKIVINMNIPC-GGNQSQWLLSGAALFLKA 4317
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Cavefish
Match: DYNC2H1 (dynein cytoplasmic 2 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2962]) HSP 1 Score: 4319.23 bits (11201), Expect = 0.000e+0 Identity = 2219/4281 (51.83%), Postives = 3015/4281 (70.43%), Query Frame = 3
Query: 240 FID--NKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWND---SLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPP--TKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQS-KTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRN-AEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKS--LMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDL-PVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWG-SREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPK-WIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVN--GSGNFYGKIQL------PSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLK 12989
F+D N+FI + D++ LVF K P +IT +N++ ++V+T+ E+P+ +LY ++ ++ P LL D DP++Q L+SELE GLGS++R L K S GI + DE +W + ++ SS + + +EL + N E S SL ++ EN +L+D+W+ P YP+ RM+ LM+II + L R +Q +L L WED Y V+E+L + + +C W+ C+ L + WK+Y PH W D L+ + N RL E+ +R V E++ +L R+ Q+ F+ F + P+ YNPYTEP+W+ AV +F R I PAE +LK+ ++ E PQQ L++FQ++ ++I RP +S L ERE LL +L K LR DF H + K P +N + ++ IVW +QL K+ L + +L L GF F + + E++ + QEQFE W++++ L D + + R+MEL DG L ++YS+RLV+L+REVR LS LG+ I + AA+ +KFY +A+ILKQVA FYNTI+ QMI Q+ M+L+ A+ FE+++K + + K + W N +EL +I +LQ A+ + ++NR LRK H +K+ LMG+DLLRQQQ+WKD L E+R +E+Q + W++H +HQLYKALEYQY +GLEALN+NLPEI +DL+++QGRLQF P FEE+++KY++E+K+FI++PNQF+G+ S PG + IF +IERNA GF+ Y KAE LF RL + + FKEW++LG +D+E ++H D+E+NFK +K KGKE+E+LP+ K+DCITVNC P+K +D LIQ +FD LL +LRK+I+G I ++D+++T +++ LS RP++IDEI +A H++ + + Q ++E+ N LLR+VAGGG+D++S L+ KWDKFELMMES Q+M++EQ+EVMK ++L+R + + QD+ KF+ RW+ L+P D+++SG A +++ I++KK E EL + L +DCEHF +EP + +L + KD+ + MW+ +EE+Q GL +A++DW++FRS+ + FEE L W ++LR E TM++ LQKE+D YK +P+LK++RGE LSQDHWL++FRLL +P+G TLE L R +L+ II A +K+LN +A EV+IREA+RELELWGAGA F L+EY DS ++LI++WR++ SQVGDN+CLLQSLKDSPYY+ F DK ++WE +L+DLD++L +LN IQRKWVYLEPIFG+ ALP+E++RF+RVD+DFR+IM DV R++R+ SL + +GM+N L T+ DQLQRCQK+LN++LEEKRS F RFYFIGDDDLLEILGQ+TNP VI++HLKKLF GI+ VDF+ I MKSL+GE V LRN + I+S+VE WL L+ EMK TL L ++ ++ G++ ++YPSQILCL+E I FT E + + N+ L+ EL+ KL+ YTN S + T V LKLK+L+LD +HN+ ++ +LL+ + +W W KQLRFY S +Q C I MVDA GNA KLVHTPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG LFGRQVLVFNCDEGIDVKSMGRIF+GL+KCG+WGCFDEFNRLEEAVLSAVSMQIQ IQ+ +KN LL + V +D NS +FITLNPAGKGYGGRQKLPDNLKQLFRPVAM+ PDN+LIAEVIL S+GFK KELG KLVAIFNL+RELLTPQQHYDWGLRALKTVL+G +LL++ K + Q N E+ L+VQALR+NT+SKLT+AD F++L++DVFP +D K++EY+ L +A+ +E + + Q KK LE+YEQL+QRMGVV+VGPSG+GKST+WKLLR AL ++ VK + +NPKA+ R QLLGHID+DTREW+DGVLT SARQVV+EPQE+ SWI+CDGD+DPEW+ESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E TDV SL+ +WL++++E ++ L +++D+F+++LD + K+N+F + TS VGTV NGLS+L+ + + F V LI+GLGGNL+ SR+ FA V E P+ K L+ Y++ +RL Y + + L ++ + + P+I TAD+QR L F WL QPF+L GPEGCGK ++L + F KL+S QV LHCSAQT+ + VLQKL+ C+ ++S+TGRVYRP++SE L+LYLKDINLP+ DKWGTS +I+FLQQV+TY GFYD NLE+VGL+ +QIV SM++ ++GR +L++RFTSI + +QL IY+AYL PVL+R + HP WS +V LA +++++Y Q+K+KFTVDDYSHYLFTP LTQWVLSLLRYDL P A S+LE+++YE+ R+F+DR+VSS D IL + I +W +V D+++D +FVTWG S E + P P GK LG+L + L + I +G++ Y RE R+LD++ F EV D ++++DR L+ P GS+LLAG+SGVGRRT +VSHMH + +PK+ R Y LK FK DLK+ +Q AG+EG+ VLLLED+QF+ P +LE++NSLL+SGEVPGLY+ EELEP+L SLKD A++ G G + NYF++R++ LH++LIMDC+N NF INC+SNPA ++ CSVQW+E WS SM KIP ML++ +E KT L +D S FL +H++C +T Y++F+++Y IY K+ E+ RQ H+Q G+ K++EAK +V ELK +AAEQS LL KQ EAD AL++IT MQ A+++K EMEKL K +E + +RK I+DEL ++P V +A+ AV +IKS LSEIR+LR PPDVIRDILEGVL +MG DTSWVSM++FL KRG++E+I TFDAR IT E R VEELL R K SFDPKNAKRAS AAAPLAAWVKANV+YS+ LEKI PLE+EQ L NL E + LE ++ V + V ++ F+ T +AAKLE ++ A ETISAAE L+ +L+ E RW Q+ E++ EL+ L + LAAA + Y+ ++PED R+ K+ WME +GL+KFD+R FL +E EQL WK EGL SD+LSMENALVILQ + PFLIDPSS AT WL+ H K+ +LE++NQQDS+F TVLEL+VRFGKTLIIQEVDG+EPVLYPLLR DLI+QGPR VVQ+GDK++DYN DF+LFLATRNP P +PPDA ++++ VNFTTT+AGL+GQLLALT+QH KP+LE KT LLQ+EE+ KI+L+ +EESLL+ LA A GNIL NK+L+ SLN+TK SS I SL ES +LQ +LD+ERDA+LPLAE S ++FVI+DL +INNMYRFSL SFLR+F RAL T + S + +R +L A L+ +VYEYVCRS+FK+D+LMFALH P+LF+ EW+ FTG + D +P +I ++ P L+ L + D LW F++SS CE+EIP S+ KLSLFQ++L++QALRPDRLQSA++ F L +K LSP +NL ++Y ET+ EP+L+IISPGADPSQ+L EL++ +G + Y+++AMGQGQAD+ L +L +C ++G+WLCLKNLHLVT+WLP+LEKELNS++P FRLW+TAE H F+ ILLQSSLKITYEAPPG+K NLLR+Y++W+ + ISK G RA +LF LAWFHA+ QERRN+IPQGWTKFYEFS++DLRAG +I+D++ + + QW+ +HGL E+AI+GGRVDN D+R + ++ Y+ SV+ + K ++ DY +++ L + + PSFF LP NI+RS+QRI S+QVI QLRIL R G+KFD+++WS L+PVLN WK LNQG ++I+ + S + SPV++F+QLE++N+I+LV+ +H SL SLSKV++G+ LLT +V L+ LL + P W +WEGPE+P Y+R ++ +A AV+ W + EK+ L S LDL ELFHPDTFLNALRQ TAR + SMD LKFV W G +K VK+G L +EGC FDG ++E DS S+ +P + W+ ++ P YSE++ + LP+Y R ++VT + +PC G D+WIQSG ALFLK
Sbjct: 38 FLDDANQFILVTS-SDGDQLQRVLVFFKLHPCVITEENVSRAVLVSTMLESPVHTLYQTLRQVFNPALLQDEKWSQAFDPRLQSLLSELEEGLGSVLRHTLPKDS----------GIVTPSDEFQYWAELGQTVEKSSKRERAAHFSELFKPIDYSNLE-----SLSLLDALELAENSRDVLDDVWRQNEHTP-YPEIRMRRLMDIIGSSLGRFVQKKLCVLHLWEDPYLTVRENLREGVTLCEQWVTACEHLTGQLWKRYSPHLWEGDK-LHPHGLKNLIQRLEEVLQIRAVQEKLQHLLSERQ-QQVSASRVFEPFSGLNPVLYNPYTEPLWRAAVSQFERLIAPAEEEAARKLKIYIRDVQ--ESPQQCLQVFQKHREIIKRPTVSKELQSEREILLTRLQDFCKGLRADFESRCHGAPGEKTGPLAGRNLPEVVNNIVWVRQLLMKVENSLKMGEALLTGLLGFGGFARFCADLQEQLKVYEQEQFEDWSRDLLSGLADPKSG-----ISNRVMELDHMDGKLKIHYSERLVSLLREVRQLSALGFSIPTKIQQAANTAEKFYRQALILKQVAHFYNTIDQQMILSQRPMLLNYALAFEQVIKVLQHHYYRGKMQITWENTKELELYISRLQNAAEKLSAENRKLRKWHTNFIDKVGVLMGVDLLRQQQRWKDGLQELRTGFATLESQGIRVSDMRAWRQHWNHQLYKALEYQYQVGLEALNKNLPEIHIDLIFKQGRLQFRPPFEEVRAKYYRELKRFISIPNQFRGV--SEPGEEPIFSHMIERNANGFLTVYSKAEVLFSRLLSVQDTFKEWVVLGQVDMEALAEKHLHSAQDWERNFKTLKAKGKESERLPSVEKVDCITVNCEPVKTVIDDLIQKLFDTLLATLRKSIQGHIQAIDSFVTGAMETLSTRPESIDEIGDANAKHSQLQAKKPEVVPQFQQAEEKNRLLRSVAGGGVDSISSLRAKWDKFELMMESHQLMIKEQVEVMKESVLTRVQVYLQDLQKFHLRWEQLRPSDDVIESGDHAALQRSLESIQEKKEEFNELEETRKKLLEDCEHFNLEPPDVSLAYDTMKDLQECSEMWALYEEFQNGLNQIAQQDWITFRSKTHEFEELLFAWHDRLRKLQEHNTMSVMLQKEVDKYKAAVPVLKYVRGEHLSQDHWLDLFRLLGLPKGTTLEKLLFRDLLNVTHTIIDKALELKDLNSRAHAEVSIREALRELELWGAGACFSLLEYRDSSGVQLNLIRDWREVFSQVGDNRCLLQSLKDSPYYQSFHDKVSLWETRLSDLDDFLHSLNAIQRKWVYLEPIFGRGALPREQARFQRVDQDFRAIMGDVQRDSRMTSLTARAGMRNTLVTLQDQLQRCQKSLNDFLEEKRSAFSRFYFIGDDDLLEILGQATNPTVIQTHLKKLFAGIHSVDFDTSFSKITAMKSLEGETVPLRNTITISSDVEVWLSGLSTEMKETLKSLLCECVRAVKRG-----GVDPNRYPSQILCLAEQIQFTEDVENAIRQQNLHQLELELIAKLDHYTNTDTSSESGGTSSVLQLKLKALVLDVIHNLSVVRELLETQVHNTDDWLWKKQLRFYLNS-EQHCTIHMVDA---------GNAAKLVHTPLTDKCYLTLTQAMRMGLGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGIDVKSMGRIFVGLMKCGAWGCFDEFNRLEEAVLSAVSMQIQAIQNSLKNHTATCQLLGKEVELDPNSGVFITLNPAGKGYGGRQKLPDNLKQLFRPVAMTTPDNELIAEVILYSEGFKEGKELGCKLVAIFNLARELLTPQQHYDWGLRALKTVLRGCGSLLQLQKKQQNNQNNIK---------ESGLVVQALRLNTMSKLTFADSSRFDALVRDVFPGVDFKDVEYEALNAALLAAYEEARLEVIPSQIKKALELYEQLKQRMGVVVVGPSGAGKSTLWKLLRAALGRLDLQVKQHTLNPKAMQRHQLLGHIDMDTREWTDGVLTASARQVVREPQEVSSWIVCDGDVDPEWVESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSCASPATISRMGMIFLSDEDTDVGSLLKAWLRREEEQNRVNLENWINDYFHRALDLVFKQNDFVVETSLVGTVLNGLSHLRGVCERGQFVVGLIRGLGGNLHLKSRQEFAKEVLSWARESPPDPRKP--LDVYYDSDSSRLRAYELQRGDGLCVEDFSNPYTL--PVIHTADMQRALHVFTHWLRPGHTQPFLLVGPEGCGKGYWMLLRYAFSKLRSTQVAVLHCSAQTSSLQVLQKLSHTCVCLSSSTGRVYRPRDSETLVLYLKDINLPRPDKWGTSNIITFLQQVLTYHGFYDENLEWVGLENIQIVASMSAGGALGRHTLTSRFTSI----RGAIAPLEQLQTIYSAYLSPVLQRTLGNHPTWSSAGRVHQLAGSLVQIYEQVKAKFTVDDYSHYLFTPCVLTQWVLSLLRYDLTPGKCVTPADSVLEVIAYEARRLFRDRIVSSKDLNAFDNILSSVIRGDWGSDVLDNMSDTFFVTWGASHEGRNPNQPLPPYGKPLGRLNTSDLTEVIRKGVVMYGRENRELDLLFFPEVLDFMSRVDRALSSPAGSLLLAGRSGVGRRTAVCVVSHMHGATIYTPKISRSYSLKHFKTDLKTVMQFAGIEGQQTVLLLEDYQFVHPSFLEMVNSLLSSGEVPGLYSAEELEPLLSSLKDQASQDGFTGPIFNYFSNRVQQNLHVVLIMDCTNENFTINCESNPALYRKCSVQWMEGWSESSMKKIPEMLLSGAGEQE----------EKTSLN-ADFFRS-FLRIHESCREFGATPSQYLSFLRVYQSIYSTKQKELTQRQQHLQAGVAKLNEAKSLVDELKRRAAEQSVLLKTKQAEADAALQEITLSMQNASDQKTEMEKLKGKMAQEVAKIEERKEKIEDELKEVQPLVDEAKQAVGNIKSESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNITHEIRQSVEELLHRNKASFDPKNAKRASAAAAPLAAWVKANVQYSHVLEKIQPLESEQAGLMENLRKTESRKNKLEGQLNSVGEKVLELKEKFQCRTTEAAKLEADVSRAQETISAAEKLIHQLDGEHTRWTTQVDEISEELATLPKRVQLAAAFITYLSAAPEDHRRAKLHTWMENSGLQKFDLRHFLCSESEQLIWKSEGLPSDDLSMENALVILQSVACPFLIDPSSRATEWLRIHLKEHRLEVINQQDSSFMTVLELAVRFGKTLIIQEVDGVEPVLYPLLRRDLIAQGPRYVVQIGDKVVDYNEDFRLFLATRNPSPFIPPDAASVITEVNFTTTRAGLRGQLLALTIQHEKPELESEKTKLLQQEEEKKIQLALLEESLLETLATAQGNILENKELIESLNQTKASSALIHDSLSESHRLQTALDQERDAYLPLAERASMMYFVITDLCRINNMYRFSLASFLRIFHRALQTKQESDSTEVRIAALEASLKSMVYEYVCRSLFKADQLMFALHFVKGMHPELFQENEWDAFTGLIVGDMERAEEKLPANFI----SIHFHYRTPRSPSLYQSLCLNDSGLWMSFSRSSTCEQEIPSSIAKKLSLFQQVLVVQALRPDRLQSAMAAFASRALGMKELSPPPLNLRRVY-GETVETEPVLLIISPGADPSQELLELASDTVGRDNYHELAMGQGQADVALQVLRECVRSGEWLCLKNLHLVTAWLPLLEKELNSMQPKAGFRLWLTAEVHANFTPILLQSSLKITYEAPPGLKKNLLRTYESWTSNQISKGGQTARAQSLFCLAWFHAVCQERRNYIPQGWTKFYEFSLSDLRAGFDIIDRLF-EGGKVFQWECVHGLLESAIYGGRVDNVCDLRAV--FVLTYYLSSVLKILCQCKYLIKREMLKYSVCVCVVCVCDYRSVVESLPEDDRPSFFGLPANIERSAQRITSTQVISQLRILSRSVAAGSKFDREVWSSGLSPVLNLWKRLNQGSSLIQQKV--SPPAEAVGSPVLSFVQLEQFNAIRLVQSIHQSLASLSKVIRGTCLLTADVHKLATALLNQECPLSWQSKWEGPEDPMQYLRAVVARALAVQSWVDRVEKNTLRSDTLDLSELFHPDTFLNALRQETARAMGCSMDSLKFVASWKGQITGSKLQVKVGGLQVEGCTFDGNRLSENQHDSPSVCAVPACYMAWIPQSVPGCYSEEECVWLPVYTSAERVRVVTNVQLPC-GGNPDQWIQSGAALFLK 4235
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Cavefish
Match: dnah2 (dynein, axonemal, heavy chain 2 [Source:ZFIN;Acc:ZDB-GENE-130530-910]) HSP 1 Score: 1246.49 bits (3224), Expect = 0.000e+0 Identity = 964/3539 (27.24%), Postives = 1712/3539 (48.38%), Query Frame = 3
Query: 2772 IKIDCITVNCAPIKMSVDTLI---QNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLR----TVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMW-------SQFEEYQTG-LQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIF----GKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNK---DIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLR-MSNQSNYGINADKYPSQILCLSEMIHFTA---RC----EELLNENNIITLKKELVKKLNIYTNA-KMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQT-------VKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTV------YNGLSNLKAIKNKAH-----------FSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDT--QQPFILSGPEGCGKSLMLNHCFQKLKSVQVT--TLHCSAQTTPVHVLQKLNQACI--IINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPK-HPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYS-HYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKD-TIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFS-------------TSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAP----LENEQNQLKRN---LENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKM-QLWMEK-TGLE-----KFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF-TGTFISDKSDR-NITVPKWI---DADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLK---PHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSG-TRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRD-----YLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSST-----DSP----VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDEL--KFVCRWGGSN---VSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRD------KIVTKIDIPCQSGQQDKWIQSGVALFL 12986
+ + + ++C+P+K S+ Q F LL+ + + + ++L ++ LS+ PQ + E+ E D ++I SQI + +L +V D + L +W F+ ++ +M+++ + K+ + ++F++ + + P GS + A+++I + +LE L + + F+ E ++ + KDID +W + ++E++ G +L E+ S Y + L + +L++ + + + I+ +K IP++ +R + HW ++ + + TL I+ E +HAE I E++ A+ E++I +++ + + Y D K ++ + DNQ L ++K S + R F+ + WE L+ + E ++ + +QR+W+YLE IF + LP E + F ++ +++IM +N++N L G+ LS M +L+ QK+L+ YLE KR +FPRFYF+ +DDLLEILGQS NP ++ HLKK F I + NK + M S DGE VE + VL+ VE WL ++ M+ TL D L L+ M+ + + + +P Q+L + I +T +C +E +++ + ++KK+ V L+ Y++A + +LS + LK+ +L+ VH D+ID+L C V ++WL QLR Y + C+I+ + F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC +G+D KSMGR++ GL + G+WGCFDEFNR+ VLS V+ QI I + + R + + + IFIT+NP GY GR +LPDNLK +FRP++M PD+ LIAE+ L +GF N K L +K+ ++ L+ + L+ Q HYD+GLRAL ++L+ A K +++ D ++++ +++ ++KLT D F +I+D+FP ++ I+Y L IEE + + + K++++YE R +IVG +GS KS W++L+ AL+ + + V Y +NPKA+ +L G D+ T EW+DGVL+ R + + + WI+ DG +D WIES+NSV+DDN++LT+ +GERI V+ +FE DL+ ASPAT+SR GM++ K V SW+ K+ + + L D + K++ + + + + + V Y+ L++ + N A F LI + +++E+ R+ ++ E+ + P NK + YY + K ++ + + KI+ P T D R + +NS Q P +L+GP G GK+ + Q L + T T++ S+QTT +V QA I + T Y P ++++ +L D+N+P +D +G+ + L+ I Y +YD ++ +D + + GR+ +S R S L ++++P++ Q+ I+ + L+ + PI S +L +E+Y + ++F HYLF D+++ LLR +++ L I +E R+F DRLV + +L + S + + + + +G + + K+L L+D + G++ S ++LF++ ++V ++ RV+++P G++LL G G GR++ S L +++ + ++ + Y ++F+ D+K + GV+ + V L D Q ++ +LE IN++L+SGEVP LY ++E E + +L D A + ++ NY +R+++ LHI+L M F + PA ++ W +W +D++L++ ++ + + N K +T++ F+ +H + +FS T +Y+ + Y ++ +K+ E+ + + ++ G+ KI + + V + + + K + E Q + ++ L I + A E++ + + K G E + +L P +++A A+ + D++EI++ PP ++ +++ V+++ G + +W + LG+ +++ FD I+ ++ + T + F P+ R S+AA L WV+A Y + P L QL L AE K +++E+ + + E + +E +L A + +S L E RW + + L ++ L LLAAA + YM + R+E + +WM++ LE F+ FL+ +W +GL SD S EN +++ +G P ++DP A W+KN R L++++ Q +F +LE +V+FG +++Q V + L+P L P+L G R +++LGDK ++YNPDF+ ++ T+ P P+ + VNF + GL+ QLL + ++ +P+LEE+K +L+ K +L ++E+ +L+ L ATG++L++ L+ +L +K ++ +S LE S + ++ +D R+A+ P A+ S LFFV++D+ +I+ MY+FSL +++ LF ++ S+ S R +L VY Y CR +F+ +L+F+ HM C + E+ F G + DK + + W+ + D + LA+ + S D WHQ+ SSE E +P + + QK+LI+++LR DR+ ++ F + L + + P +++ + E T + P++ ++SPG DP+ L +L+ ++ +++GQGQA I ++ + +NG W+ L N HL SW+P L+K + L+ H DFRLW+++ PH F +LQ+ +K+T E P GVK+N+ R Y +E S+ LFSL +FH+I+ ER+ F+ GW Y F+ +D +E L + I W + L +GG V + +D R+L++YI YF + VN F+ LP+ RD Y I QL P F N D +SQ + + L LQ V T SRE K+L + ++ +P+ + ST D P VV +++RYN+ L+ + +SL L K +KG +++ ++ + +C+ + P +W + + + + R L + + WAE + L L P FL A+ Q +AR +S+D L +F+ N K V I L++EG +D C ++ + L+ P+ + +M S P YY +R V +D+ + + WI+ G AL +
Sbjct: 999 LSVQFVLLDCSPLKFSLVQHCNEWQGKFTQLLSLMAST---RLKELHSFLQDNAHRLSQPPQTLVELVEGLKLLETLQGDLNKIESQIPPIHEQFAILEKYEVSVEREVQDLLEALNGEWQGFQQVVIDSDIMLKKHKDKFKSGLFFSAEEFKKKMQTTMQDFNSTGP------FGSNVSSEAALEQISVLRAQLESLKEEEGTIRHGLSIFKTEQPTSKDMQNLEKDIDYLLQVWEISQQWDTHWDEWKAGQFASLQTENMESTAQTMY---KNLNKLSRELKDKQWEIVEFS-KNRIEQFKRTIPMILDLRDPAMRDRHWNQIKQEMQRSFDHNSAEFTLEKIVALGLE--QHAERICEISGAARKELSIEQSLEGIAKTWEETSLDIAPYKD---------KGTEEVFQALEDNQVTLSTMKASRFVRAFEKEVDRWERCLSLVLEVIEMILTVQRQWMYLEIIFLGEDIRKQLPHESTEFDDINSSWKTIMDRLNKDNNALRGTHHPGLLEKLSEMNSKLEEIQKSLDMYLETKRQIFPRFYFLSNDDLLEILGQSRNPDAVQPHLKKCFDNIKSLRINKVRNNKSEAAGMFSADGEFVEFTHPVLLEGPVEAWLCDVERTMRWTLKDTLRNCRTALKKMTGKRDKWVK--DWPGQMLITASQIQWTTDVTKCLITGKESADKSALKSMKKKQVSMLHRYSDAIRGNLSK-----ILRLKIVALVTVEVHARDVIDKLAKAGCCDVNAFDWLCQLRLYWEKDVDDCIIRQTNTHFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKGLGMYVIVVNCSDGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSALSAGLTNFIFEGRDICLVSSCGIFITMNP---GYAGRTELPDNLKSMFRPISMVVPDSTLIAEITLFGEGFNNCKVLAKKVFTLYCLAVQQLSKQDHYDFGLRALTSLLRYAGK-----KRRVRPDIAD-----------EEILLMSMKDMNIAKLTSTDLPLFNGIIQDLFPAVETPTIDYGKLKETIEEELHQSGLQVTPFTVTKVIQLYETKNSRHSSMIVGKTGSSKSVTWQILQKALSAMHRKGEPGFNLVHEYPLNPKAVSLGELYGEYDLSTNEWTDGVLSSLMRIACADEKPDEKWIVFDGPVDTLWIESMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAVASPATVSRCGMVYNDYSDLGWKPYVQSWIDKRQKMEVDHLKRLFDRYIKKTISFKRTHCKELVPITELNGVISLCRLYDSLASPENGVNPADNENYGRMVELWFIFSLIWSICASVDEDGRKKIDNFLREM-EGTFP--NKDTIYEYYVDTKNKTWASFEDKLPKGWRYPSNAPFYKIMVP---TVDTVR----YHFLVNSLVCGQYPVLLTGPVGTGKTSVAQSVLQGLDPAKWTMLTINMSSQTTSNNV-----QAIIESRVEKRTKGTYVPVGGKKMLAFLDDLNMPAVDDFGSQPPLELLRLWIDYGFWYDRQMK---MD--MFLLASMGPPGGGRTHISGRLQSRFNLINMTFPAESQIKHIFGTMINQKLQEFQEEVKPIGS------ILTQATLELYYAISARFLPTPAKIHYLFNLRDISKVFQGLLRSHRDFHDTKQSITRLWI--HECFRVFSDRLVDQADTEAFVALLAEKLGSLFDLTYHNICPNKQQPIFGDFLKEPHVYEDLLDFKALKGFMESQLEDYNLTPGVVPMS-------LVLFRDAIEHVTRVVRVISQPRGNMLLVGIGGSGRQSLSRLAAYICEYMVFQVEVTKQYRKQEFREDIKKLYRLTGVDNKPTVFLFNDTQIIDESFLEDINNILSSGEVPNLYKSDEFEEVQSALSDSARKENVLETADAMFNYLIERVRNNLHIVLCMSPVGEPFRNRIRQYPALVNCTTLDWFSEWPQDALLEVAERYLDGL-------ILGNVEKIQTKVA------RIFVTMHQSV-AQFSQRMKLELKRHNYVTPTNYLELVSGYKKLLAEKRAELGEQVSKLRNGLFKIDDTRSKVEAMSVELEDAKKKVAEIQKQCEEYLVVIVQQKREADEQQMAVSAHSEKIGAEEIKCKAMAENAQRDLDEALPALEEAMKALESLNKKDMTEIKSYGRPPALVETVMQAVMILRGC-EPTWAEAKRQLGESNFIKQLVHFDKDNISDRVLKKIGQYCT--QPDFQPEIIGRVSLAAKSLCMWVRAMEVYGRIYRVVEPKRARLHGAMTQLAEKQAALAEAENKRREVEEKLKQLKNQYDEKLNQKEDLRKKSEDMELKLDRAGKLVSG-------LAGERVRWEQTVESLEKDMGYLVGDCLLAAAFLSYMGPFLSNYREELLTNIWMKQFRDLEVPCSPGFNFATFLSKPTAVRDWNIQGLPSDAFSTENGVIVTRGNRWPLMVDPQGQALKWIKNMESKRGLKVIDLQMPDFLRILENAVQFGSPVLLQNVQEELDPSLAPILNKSFTHIGGRVLLKLGDKEVEYNPDFQFYITTKLSNPHYTPEISTKTTIVNFAVKEQGLEAQLLGIVVRRERPELEEQKDSLVINIASGKRKLQELEDEILRLLNEATGSLLDDVQLVNTLQTSKITATEVSDQLETSEQTEIKIDTAREAYRPCAQRASILFFVLNDMGRIDPMYQFSLDAYIDLFNLSIEKSQRSHKLEERIINLNDYHTYAVYRYTCRGLFERHKLLFSFHM--CAKILEVAGKLNMDEYSFFLRGGLVLDKEGQMDNPCTSWLADSNWDNITELDKLANFHGLMSSFEKYPKD--WHQWYTSSEPENAPLPGEWETVCNELQKMLIVRSLRQDRVSFCVNSFIINNLGSRFVEPPVLDMKAVMEDST-TKTPLIFVLSPGVDPTGALVQLAEASGMGPSFHALSLGQGQAPIATRMIKEGVKNGHWVFLANCHLSLSWMPQLDKLVEQLQVEDSHPDFRLWLSSSPHPEFPIAILQAGIKMTTEPPKGVKSNMKRLYQLVTESQFSRCSRPVVYRKLLFSLCFFHSILLERKKFLQLGWNIVYSFNDSDFEV-SENLMSLYLDEYEEIPWDALKYLIAGVNYGGHVTDDWDRRLLTTYINDYFCEGAVNTP--FFKLSSLPTYYIPRDGSQDTYREYIRQLPPVEHPEVFGQHPNADIASQISETRTLFDTLLSLQP-QVTSTTATGAGPSRED-------KVLEISAD-VRQKVPELVDYESTQKLLQDDPSPLNVVLLQEIQRYNA--LLHTIRTSLTELEKGIKGLVVMSSSLEEMFQCIHDARVPPLWEKAYPSLKPLASWTRDLCQRVEQFAHWAETAHPPVLFW----LSGFTFPTGFLTAVLQSSARQHNVSVDTLSWEFIVSTVDDNNLLFPPKDGVFIRGLYLEGAGWDKK--NSCLVEAEPMQLVCPMPTIHFRPVENRKKVAKNMYSCPCYYFPVRSGGAGRPSFVVGVDLKSGAVSYEHWIKRGTALLM 4403
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Cavefish
Match: si:dkeyp-86b9.1 (dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]) HSP 1 Score: 1127.08 bits (2914), Expect = 0.000e+0 Identity = 886/3170 (27.95%), Postives = 1536/3170 (48.45%), Query Frame = 3
Query: 3888 FQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSL---DGEVVELRNQVLITSEVENWLGNLNNEMKTT----LSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTF--IVHDLK------LKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEP-QEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWI---------AKRNEFTISTSNVGTVYNGLSNLKAI---------KNKAHFSVCLIKGLGGNLNENSRETFALWVYELT------DEKTPEMNKQ------NVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSD---TQQPFILSGPEGCGKSLMLNHCFQKLKS--VQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQI----VCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKL----LANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDN---TAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLND-VWFVTWGS--REXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANE--SGH-RGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEEN-VILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEK-------FDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDG-LEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMS-HCCRPDLFKPQ-EWELF-TGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVL------NIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKV-IGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSL-KPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNR----NIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYG------KIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSR--ELNPV-------LNRWKILNQGLNIIKASLPDSL------KRSSTD-SP--VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPF-DYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIG------NLHIEGCLFD---GTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDK-----IVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
F + Y ++ +I + DN LQS+ S + F + WE L+ + E ++ +QRKW+YLE IF ++ LP+E +F +D+ F+ IMSD R+ + C + + L + D L+RCQK+LN+YL+ KR+ FPRF+FI DD+LL ILG S+ P ++ H+ K++ I + F+ +L +GEV+EL+ V VE+W+ + EM+ T + + Y Q ++ ++ ++ Y ++ + +T E++ + + + +K+ +K+ KM D+ I LK L ++++ VH DI+D + + E+EW QLRFY K ++ AEF+Y YEY G +LV TPLTD+ YLTLTQ + M LGG P GPAGTGKTES K L G +V NC EG+D ++G+IF GL +CG+WGCFDEFNR++ +VLS +S QIQ I++ + +++ + +++D IFIT+NP GY GR +LP+++K LFRPV + PD I E++L S+GF AK L +K+ ++ L+RE L+ Q HYD+GLRALK+VL A L K D E+V ++++ALR L K + D F LI D+FP +D + Y N A+E +++E L Q K++++YE + R ++VGP+G GKS + L A ++G K Y +NPKA+ +L G +D TR+W+DG+L+ R + + ++ + +I+ DGD+D W+E++NSV+DDN+LLT+ +GERI+ + +FE DL ASPAT+SR GM+F+ + W+ + +Q L + + ++ + ++ + + +++ V L A+ + + F L LG L E R+ F V +L+ DEKT + + +++F+ + + +S + + D K + L+ T D R WL ++P +L G G K+ + L V T++ S++TT + + + L + + T Y P + L++++ D+N+P++D++GT Q I+ L+ ++ G YD E L+ Q+ + + GR+ + +RF S+ + +I +P ++ L+ IY++ LK + + I + K+ L T+I+ SKF HY+F DL++ + L +T+ T + + E +R+F DRL++ + G + + I + E+ ++ D + F + + E + + L E L+ +Y+ ++++LF + D++ ++ R++ G LL G G G+++ + L + + + RGY F+ DLK+ G+E + V L D E +LELIN++L SG VP L+ +E E +L ++D A + SGH + S+ YF ++ LHI+L M C++ P + W W ++ + + + P + ++ + GS S + T ++Y++FI Y + K I + ++ G+ K+ EA +A+L K AEQ +L EK + L++I++ A E+K E+ + E+N VIL ++K A + LA P ++ AR A+ D+ SD++EIR+ PP ++ + E +L++ G + +W + + + + + D I+ V L S + A S A + + +V+A + Y +I P + +L++N ++++++ ++ + + K + + + + L+ E + + AA+ L+ L +E +RW + + EL + L L++AA + Y + D R E + +K LE+ F + LT E E W E L DELS++N ++ + P IDP A W+K + L+I + D +F LE+++++G + Q+VD ++PV+ +L ++ RQV+ LGDK +DY+P+FKL+L T+ P+ P +N+T T GL+ QLL++ + + +LEE++ L+QE + K L +E+SLL+ELA +TGN+L+N +L+ +L +TK + + + L+ + +D+ RD + P A+ G+ LFFV+++++ +N+MY++SL SFL +F +L S ++ R ++++ L VY Y C +F+ +L+F+ +M+ + + PQ E E F G +KS R W+ I L P + L N K+ W F S + P ++ L++FQK+L+++ R DR+ A+S + + K++ P ++ I+E T N PI+ I+SPG +P+ DL +L+ + G+ R +AMGQGQ + L LL G WL L+N HL+ WL LEK L + KPH DFRLW+T +P F +LQ SLK+ E P G+K N+ +Y + + + ++ LA+FHA++QERR + GW Y+F+ +D EIL+ + K++ +I W + L ++GGR + FD R+L+ Y+ Y D + + F+ ++P SK Y+ I L N+P F L N + + T+ +D+W+ EL P ++R + + Q I+ LP + K+ D SP VV +LER+N +LV + SL L + L G ++ E+ ++ L GQ P +W + + ++M + + W E+ E ++ L L P+++L AL Q T R +D + + K G L++EG +D G ++ ++ +V LP + V ++ ++ + + P+Y +R +V + D+ + W+ GV L+L S
Sbjct: 1281 FSVQRYFKGTQERGYILGSVDEIQQNLDDNAVNLQSMAGSRFIGPFLNVIQQWEKNLSLISEVIEVWMLVQRKWMYLESIFIGGDIRSQLPEEAKKFDHIDKMFKKIMSDTVRDPGIKRCCLVPNRLSDLQNLSDGLERCQKSLNDYLDSKRNAFPRFFFISDDELLSILG-SSEPACVQEHMIKMYDNIASLRFDSGTNGETVAGALVSAEGEVMELKQPVPAEGRVEDWMTAVLLEMRRTNRLITKEAIFYYCQK---KSRVDWMLD---YQGMVVLAGNQVWWTWEVEDVFQK--MSSGEKQAMKQYA----KKMHQQIDNLVRRITQPLKKNDRRKLNTVLIIDVHARDIVDSFVRDSITDAGEFEWESQLRFYWDKKPDDLFVRQCSAEFSYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTESTKDLAKALGLLCVVTNCGEGMDYMAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALILQLKRFQFEGQEISLDSRMGIFITMNP---GYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLLAKVLAKKMTVLYKLAREQLSKQSHYDFGLRALKSVLVMAGEL--------KRGSPDLNEDV--------VLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPNFNDAVETILEENKYSLLPNQVDKVVQMYETMMTRHTTMVVGPTGGGKSVVINTLCQAQTRLGLLTKMYALNPKAMSVIELYGILDPVTRDWTDGILSNIFRDINRPTDKKERRYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQNHCALLFEVGDLQYASPATVSRCGMVFVDPKNLRYAPYWQKWVNSRPPKEQADLRKLFEKYVPSIIEMVVEGITDGKQGEKLKTIVPQTDLNMVVQLSMMLDALLEPEDLSSEELECFFIEALYCSLGAALLETGRKKFDDLVKKLSCLVSVQDEKTLAGPGEIPGYLPTLFDFHFDGTTKKWMPWSSLVAKYIH----NPDTKFIDILVPTVDTTR-----VNWLLEQMVKVKRPVVLVGESGTSKTATTQNFLNNLNPDFTMVLTINFSSRTTSMDLQRSLEAS---VEKRTKETYGPPMGKSLLVFMDDLNMPRVDEYGTQQPIALLKLLLDRGGMYDRGKE---LNCKQLKDLGFIAAMGKAGGGRNEVDSRFISLFSVFNIPFPEEEALHLIYSSILKGHTRPF--EECIRNMCDKLTFCTLELYKTIIKDLPPTPSKF------HYIFNLRDLSR-----VYNGLTLTNAERFLTEAQFVRVWRNECLRVFYDRLINETDKALVQGHIKSLIQEHFGSELDSAMRDPILFGDYRTALSESEPRVYEDIQDYDACKALFQEILE--------EYNENKTRMNLVLFDDALDHLTRVHRIIRMDRGHALLVGVGGSGKQSLTKLAAFTAGCDVFEIVLSRGYSESNFREDLKTLYVKLGIENKRTVFLFTDAHVAEEGFLELINNMLTSGMVPALFPDDEKESVLNQIRDEAVKMGSGHSKESVWQYFINKSASNLHIVLGMSPVGDVLRTRCRNFPGLVNNTGIDWFLPWPPQALHAVAQSFLGESPMIPAAH-SETVIGHVCMVHGSVGEFSTLFQ-QKLRRSNYVTPKNYLDFISTYSTLLQDKDQFILAQCKRLEGGLDKLEEASVQLADLNKKLAEQKVVLAEKSSACESLLQEISTNTAIAEEKKKLAEEKAKEIEEQNKVILVEKKDA-ESSLAEALPALEAARIALQDLDKSDVTEIRSFAKPPKQVQVVCECILVMRGHKEINWKTAKGMMSEANFLRSLMEMDCDSISGGQVKTVRGFLKNLNTSSEEMQA--ISKAGSGMLKFVEAVMGYCDVAREIKPKREKVARLEKNFFQSKRELEKIQSELEAIQKELGALGEKYSAAMGEKQLLQEEAQLMERRLIAADKLISGLGSENQRWTEDLEELKKKRVRLLGDCLISAAFLSYEGAFNWDFRNEMVYEVWQKDVLERGIPLSQPFRIESLLTDEVEISRWGSESLPPDELSVQNGILTTRASRFPMCIDPQQQALNWIKKKEEKNNLKISSFNDPDFLKQLEMAIKYGFPFLFQDVDEYIDPVIDNVLEKNVKGAEGRQVIVLGDKEVDYDPNFKLYLNTKLANPKYSPAVFGKAMVINYTVTLKGLEDQLLSVIVGFERKELEEQRERLIQETSQNKRLLKDLEDSLLRELATSTGNMLDNVELVHTLEETKSKAGEVFEKLKLAETTSADIDKLRDGYRPAAKRGAILFFVLAEMALVNSMYQYSLASFLEVFDYSLRKSLPNSILPKRLSNIMNTLTLNVYNYGCTGLFERHKLLFSFNMTIKIEQAEGRAPQEELEFFLKGNLSLEKSKRKKPC-DWLPDQGWEDIVRLNELFPNEFGALIEDIEKNPKEWKNW--FDLDSPEQAPFPMKYRDSLTVFQKLLLLRCFRVDRVYRAVSDYVTATMGEKYVQPPVISFEAIFEQST-PNSPIVFILSPGCEPANDLMKLAERSGFGTNRLKFLAMGQGQEKVALQLLETAVSRGQWLMLQNCHLLVKWLKDLEKALERITKPHPDFRLWLTTDPIRDFPIGILQKSLKVVTEPPNGLKLNMRATYFKIQLETLMSCPHPAYRSLVYVLAFFHAVVQERRKYGKIGWNVPYDFNESDFLVCMEILNTYLTKAHNQGEGSIPWGSLKYLIGEVMYGGRAIDSFDRRILTVYMDEYLGDFIFDTFQPFHFFHNKDVDYRIPPDGSKEVYVEEIESLPLANTPEVFGLHPNAEIG---------------------YYTQAARDMWTHLIELQPQTGDSGGGISRDEYIAQVARDIQNKLPSAFDLDVIRKKLGPDVSPTSVVLLQELERFN--RLVLRMSRSLSELQRALAGEVGMSSELDEVARALFNGQIPAIWRKLAPDTLKSLGNWMIHFRRRHQQYSSWVEVGE-----PAVMWLSGLHIPESYLTALVQATCRRNGWPLDRSTLYTHVTHYRSEDEVTEKPGQGCYVSGLYLEGADWDVEQGCLVR--SKPKELVVQLPILKVIPIEAHR---LRLQNTLRTPVYTTSMRRNAMGVGLVFEADL-FTTEHHSHWVLQGVCLYLNS 4339
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Cavefish
Match: ENSAMXT00000016172.2 (pep primary_assembly:Astyanax_mexicanus-2.0:4:1379218:1548247:-1 gene:ENSAMXG00000015711.2 transcript:ENSAMXT00000016172.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 1125.92 bits (2911), Expect = 0.000e+0 Identity = 870/3189 (27.28%), Postives = 1541/3189 (48.32%), Query Frame = 3
Query: 3801 IKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG-----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDI-----QHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTA-------RCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDL------KLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVK----FYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQD-EHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAH-------------FSVCLIKGLGGNLNENS----RETFA-LWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYS-----YECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVT--TLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYD-SNLEFVGLDGVQIV-CXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYS-HYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGK------LTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLAN---YFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMG-----TMDTSWVSMRNFLGK-RGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKM---------QLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSH--CCRPDLFKPQEWELFTGTFISDKSDRNITVP-KWIDADRTVAISNLASAMPELWSVLNIKDDDL------WHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIG----SERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKEL--NSLKPHKDFRLWVTAEP------HIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANA-LFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXV---ILQLRILQRFSVHGTKFDKDIWSRELNPVLNR-WKILNQGLNIIKASLPDSLKRSSTDSP--VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILIL-------KAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSN-----VSAKYSVKIGNLHIEGCLFD---GTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKI-VTKIDIPCQSGQQDKWIQSGVALFLK 12989
++ + +A E+ + + + EL+ F Y S+ L+K D++ + DNQ LQ+L S + FF ++ + W+ +L+ D + ++QR W +LE IF ++ LP++ RF +D DF+ + D ++ V+ + G+ + L + +L C+KAL EYL+ KR FPRFYFI DLL+IL T+P ++ HL KLF + F D + I M S + E V T +VE WL + + M+ T+ +++ A+ + + + YP+Q+ I +T+ R EE EN + K+ V +LN T ++ L K+ ++ VH D++ +++ Q ++ + WL QLR +++ C + DA+F Y+YEY GN P+LV TPLTD+CY+TLTQ +H+ + G P GPAGTGKTE+ K LG G V VFNC E +D KS G I+ GL + G+WGCFDEFNR+ VLS V++Q++ IQD I++K + + +N+ + IFIT+NP GY GR +LP+NLK LFRP AM PD +LI E++L ++GF A+ L RK + ++ L +ELL+ Q HYDWGLRA+K+VL A +L + + Q ++++ALR + K+ D F LI D+FP +D+ + + E + + + + K++++ E L R V +VG +G+GKS + K +LNK Q +K + +NPKA+ +L G I+ TREW DG+ + R++ WI+ DGDIDP WIESLN+V+DDN++LT+ S ERI P + +FE L A+PAT+SR G+++++ V+SW+ K++ + ++ L+ D + LD + R + I V L+ + H F I GG L ++ R F+ WV E K P ++ V +YY + + + +S +E + E+ + L+ T + R + YF L + ++P +L G G GKS+++ L + T + + TT + L + + GR Y P S+RLI ++ D+N+P++D +GT Q + ++Q + Y +YD S L+ + VQ V C +S S + R S+ ++S+P D LN IY + L L R + ++ LA ++ + ++ + F HY+F DL+ +L T L+++ +ES R+++D++V D F+ + SE + + + + + E +G+ + E L T+ L Y+ ++++LF + ++ +++R+L P G+ LL G G G+++ + L + + ++++ + +GY + K+DL + AGV+ V L+ D Q + ++L L+N LLASGE+P LY +E+E I+ S+++ G S N +F +R++ L + L + + PA + W +W ++++ + + ++ E ++ + +K + S N S L + ++T + ++ IK+Y + K+ ++ + ++ G++K++ V +LK+K A Q L +K +AD+ ++ + + + K ++ K V++ +++ +++LA EP + A++A++ + ++L+E+++ +P + ++ V+++M D SW + + + K + + F+ I ++ L F P+ S AAA L +WV VK+ ++ P N+ L +A++K+ ++ ++ +++ +A FEK TAD K + E + TIS A LV L +E RW + + + L LL A V Y+ + R E M QL + D L + + W+ EGL +D +S ENA ++ P ++DP W+KN + D L+++ + +E ++ G+ ++I+ + + ++PVL PLL + I +G + +++GDK +YNP F+L L T+ P P+ A + +NFT T+ GL+ QLLA + +P LEE K+NL +++ KI L +E++LL L++A+GN L + +L+ +L TK ++ I + ++E+ + ++E R+ + P A S L+F+++DL+KI+ MY+FSL +F +FQ+A+ + R +LI + V++Y R +F+ D+L + ++ P E + + +T P ++ I L S M E ++ D D+ W +F + E+E PQ KNK SL QK+ +++ALRPDR+ A+ F + L K++ S++ +E E+ + P+ I+SPG DP +D+ E + +G ++ ++ V++GQGQ + L ++ G W+ L+N+HLV WL LEK+L + ++FR++++AEP HI +L++S+KIT E P G+ NL ++ DN+++D + + LFSL +FHA++ ERR F PQGW + Y F+ DL +L + ++N + + + LF ++GG + + +D R+ +Y++ + ++ G LP Y I+ SP + L N + S ++ +L+++ S G+ +D ++ VL + L + N+++ + + SP VVA + ER N L + + SL L+ LKG +T +++NL + Q P+ W ++ + M L L + + +E W+ D L + L F+P +FL A+ Q TAR + +D++ C N + + L +EG +D G ++ D+ L P + V ++ + ++ P+Y R V ++ + KW +GVAL L+
Sbjct: 1259 VRAIVDRAVKEMGMEKVLTELDATWTAMEFG---YESHPRTSVPLLKSDEDLVETLEDNQVQLQNLMSSKHVAFFLEEVSSWQKRLSVADSVISIWFEVQRTWSHLESIFIGSEDIRSQLPEDSKRFEGIDTDFKELAYDAHKTPNVVEATNKPGLYSRLEDIQGRLALCEKALAEYLDTKRLAFPRFYFISSADLLDILSNGTDPHQVQRHLSKLFDNTAKMKFETDADGKPSKTGIGMFSKEEEYVPFNEPCDCTGQVEMWLNRVLDTMRATVRHEMTEAVVAYEDKPREQWLFD---YPAQVALTCTQIWWTSDVGLAFSRLEEGY-ENAMKEYYKKQVSQLNTLI----------TMLIGQLSPGDRQKVMTICTIDVHARDVVAKIIAQKVENSQAFVWLSQLRHRWDEREKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKKRFNFMGEEINLFPSVGIFITMNP---GYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFIEARLLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPERPEDQ----------------VLMRALRDFNVPKIVTDDMPVFMGLIGDLFPALDVPRKRDLDFEKFVRESVLDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGNAGTGKSQVLK----SLNKTYQNMKRRPVWADLNPKAVTNDELFGIINPATREWKDGLFSNIMRELANVSHAGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMRLVFEISHLRTATPATVSRAGILYINQADLGWNPPVSSWIDKREIQSEKANLTILFDKYLPACLDTLRSRFKKIIPIPEQSMVQMLCHLLECLLTPEHTPPDCHKELYELYFVFAAIWAFGGALFQDQLVDYRVEFSKWWVTEFKTIKFP--SQGTVFDYYIDPETKKFEPWSKMVPRFEMDPEIPLQAC---------LVHTTETIR-VSYFMERL-LERRRPIMLVGNAGTGKSVLVGGKLGSLDPDKYTIKNVPFNYYTTSAMLQAVLEKP---LEKKAGRNYGPPGSKRLIYFIDDMNMPEVDAYGTVQPHTLIRQHMDYNHWYDRSKLQLKEIHSVQYVSCMNPTSGSFTINPRLQRHFSVF---ALSFPGVDALNTIYCSILGQHLSREGFSAVVQKSGPQLVQLA---LDFHQRVTATFLPTAIKFHYIFNLRDLSNIFQGMLFCKSECM--KTPQDLVKVYLHESNRVYRDKMVED-----KDFSTFDKLQSEMVGKFYEDMEE-------ALEEAKVMNMYCHFALGIGEPRYMPVQSWESLNKTLLEALDSYNEVNAAMNLVLFGDAMSHICRINRILESPRGNALLVGVGGSGKQSLTRLAAFISSLEVFQITLKKGYGITDLKSDLGALCIKAGVKNIGTVFLMTDAQVADEKFLVLVNDLLASGEIPDLYPDDEVENIINSVRNEVRGQGLLDSRENCWKFFIERVRRQLKVALCFSPVGSKLRVRSRKFPAVVNCTVIDWFHEWPQEALESVSLRFLQEVEHIE-PEVKDSVSKFMAYVHVSVNKTSKDY-LANERRYNYTTPKSFLEQIKLYRNLLALKRKDLTMKMERLENGLQKLNSTSAQVDDLKAKLAAQEVDLKQKNEDADRLIQVVGVETEKVSREKAVADEEEEKVASIAVVVTRKQKDCEEDLAKAEPALIAAQEALNTLNKNNLTELKSFGSPVAAVTNVTAAVMVLMAPGGRVPKDRSWKAAKVMMAKVDAFLDSLMNFNKENIHENCLKAIQPYLQ--DPEFKPELVAAKSNAAAGLCSWVINIVKFYEVYCEVEPKRQALNKANAELASAQEKLSVIKAKINHLNENLAKLTAKFEKATADKLKCQQEAETTARTISLANRLVGGLASENVRWAEAVNNFKQQERTLCGDVLLITAFVSYLGYFTKRYRHELMDNTWKPYLSQLKVPIPVTPGLDPLSMLMDDADVAAWQNEGLPADRMSTENATILTSCERWPLMVDPQLQGIKWIKNKYGD-NLQVIRIGQRGYLDSIERALSAGEVVLIENLEEAVDPVLGPLLGQETIKKG--RYIKIGDKECEYNPRFRLILHTKLANPHYQPELQAQCTLMNFTVTRDGLEDQLLAAVVSMERPDLEELKSNLTKQQNGFKITLKTLEDNLLSRLSSASGNFLGDTELVENLEITKRTAAEIEEKVKEAKVTEAKINEAREHYRPAAARASLLYFIMNDLNKIHPMYQFSLKAFSVVFQKAVLKAAPDEALKQRVLNLIDSITSSVFQYTTRGLFECDKLTYTAQLAFQILLMNKEINPSELDFLLRYPVQP----GVTSPVDFLSHHSWGGIKALCS-MDEFRNL----DRDIESSAKRWKKFVECECPEKEKFPQEWKNKTSL-QKLCMMRALRPDRMNYAIRDFVEEKLGSKYVMGRSVDFAVSFE-ESGAATPMFFILSPGVDPLKDV-EKHGRTMGYTFDNQNFHNVSLGQGQEVVAEQALDLAAREGHWVILQNIHLVAKWLGTLEKKLEQHGEGSSQNFRVFISAEPSSSPEGHI-IPQGILENSIKITNEPPLGMHANLHKALDNFNQDTLEMCARENEFKSILFSLCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNYL-EANSKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLEEFIKPEMMEGELYLAPGFPLPGNMDYNGYHQYIDDALPAESPYLYGLHPNAEIGFLTQTSEKLFRTVLEMQPRDAGSGEGSGTSRD---EKVKAVLEETLEKLPEEFNMVEL-----MGKVEERSPYVVVALQECERMNI--LTQEIKRSLKELNLGLKGELTMTNDMENLQNAIYLDQVPDSWTKR------AYPSMCGLALWFTDLLNRIRELESWS----SDFNLPPAVWLAGFFNPQSFLTAIMQSTARRNEWPLDKMSLQCDVLKKNREDFSSPPREGAYVHGLFMEGARWDTQAGVIV-----DARLKELTPAIPVIFIKAVPVDKQETRNVYQCPVYKTRQRGPTYVWTFNLKTKENPS-KWTLAGVALLLQ 4324
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Cavefish
Match: dnah12 (dynein, axonemal, heavy chain 12 [Source:ZFIN;Acc:ZDB-GENE-090311-9]) HSP 1 Score: 1081.24 bits (2795), Expect = 0.000e+0 Identity = 869/3172 (27.40%), Postives = 1540/3172 (48.55%), Query Frame = 3
Query: 3597 MTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEA-LTLRHILDA-ASEIIRHAEAIKELNQKAQGEVTIREAIREL-ELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKN----ALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDF--NKDIQHIITMKSLDGEVVELRNQVLITSE----VENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHD-------LKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKD-QGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQ--EITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLAL---NKIG----QTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKK-----QDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNL---------------KAIKN--KAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYY---FNEKQNRLVTYSYECE--------EELSIDQLMSDK--KILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNH-CFQKLKSVQVTT--LHCSAQTTPVHVLQKLNQACIIINSNTGR----VYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYD-SNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQ-LKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKS---LGKLTS-EYLKDTIDRGLLQYSRECRD-LDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPI---LMSLKDLANESGHRG------SLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALK--KITSVMQGATER--KGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLI-----------MGTMDT---SWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVE-ELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKT------GLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWE------LFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELST-KVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKP---HKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSY--DNWSE-DFISKTGSGTRA--NALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFY---GKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGL----NIIKASLPDSLKRSST--DSPV--------VAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPF-DYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF 12671
M I++ ++I +K+ IP++ + G+ HW +M ++N LT + TLR +L S + H E I + A E ++ +A++ + E W + + + + +S++ +I + + D Q+++ SP+ + F+ + WE +L + + + ++Q +W+YLEPIF +P+E F+ VD+ +R +M ++ +VL S++G+ L + L++ K LN YLE+KR FPRF+F+ +D++LEIL ++ +P ++ HLKK F+GI +DF N DIQ M S +GE VEL Q++ TSE VE WL + + M +++ D ++ + + +S + ++P Q++ + +++T E + V L Y N S D +V L +L+ VH D++ +++++ T+++WL QLR+Y + + + C+I + + Y YEY GN+P+LV TPLTD+CY TL ++ LGG P GPAGTGKTE+ K L Q +VFNC +G+D +MG+ F GL G+W CFDEFNR+E VLS V+ QI IQ I+ K++ + E R+N +C A IT+NP GY GR +LPDNLK LFR VAM P+ LIAE+ L S GF NAK L K+V + L E L+ Q HYD+G+RA+K VL A NL K K + D L++++++ K D F + D+FP I + +Y +E K+ N+ +K KM++ YE + R G ++VG +GK+ + +L L N+ G + V++ +NPK+I QL G D + EW+DG++ + R+ + W++ DG ID WIES+N+VLDDN+ L + SGE IQ ++ IFE DLS ASPAT+SR GMI++ LVTSWL Q + + LL + +L + K +ST+N TV + L+ L K I+ A F+ L+ +GG+ + +SRE F ++ E+ K E ++ + FN+K + YSYE + E + + DK K+ ++ T D + + + +P + GP G GKS+ + L + ++ SA+T+ NQ+ II + + V+ P ++ I+++ D+N+P ++ +G I L+Q + +YD + + L VQ++ S GR++++ RF +CS++ S D ++ I++ + L+ + +S +++ +A T+ EVY + +++ SHY F D ++ V L L S +++ + +E R+F DRLV R ++ N + + + R P S ++ S E ++ L +Y++ ++ +++++F+ V ++++++ RVL +PGG+ LL G G GR++ + L + M ++ L P++ + Y + +++ DLK L+ AGV+G+ V LL D Q E +LE ++S+L +GEVP L+ +E + I + +++ +A ++G++ +L +F +R + LH+++ F + P+ C++ W + W +++ ++ + + + + + KT T + +L+ FL + + T Y+ I + + K++ + + G+ K++ A+ V E+K + + L + +++ K ++ ++ SV A + + E E + K E + K + +LA P ++ A A+ +K SD++ +++++ PP ++ ++ V ++ GT W + LG +++ +D I ++ E +T FDP +AS AA L W+ A Y + +AP + +++L + + +V+ +A +K E+ T + A+L+F++ + AE L+ L E RW+K +L LT L++A + Y+ + R+ + W + + F + K L + W GL +D S++N +++ P +IDP A W+KN ++ L ++ D+++ LE ++FG L+++ V + L+P L PLL + QG ++LG+ +I+++ DF+ ++ T+ P P+ VS +NF T GL+ QLL + + +P+LEE + L+ + K +L ++E+ +L+ L ++ GNIL ++ + L+ K S IS+ + + K ++ + E R+ + P+A+H S LFF I+DL+ I+ MY++SL F+ L+ ++ S S R LI +Y VCRS+F+ D+L+F+ + C L +E E L TG + +++ P W+ D++ AS +P L + + +P+ +KLS FQK++I + LRPD+++ A+S + L K + P +L + Y +++ S P++ ++SPGADP L + + K +G + +++GQGQ I + ++ + G W+CL+N HL SW+ LEK P H DFRLW+T+ P F +LQ+ +K+T E P G++ NLL+SY D S+ F S + L+ + +FHA++QER+ F P GW Y F+ +DLR L Q+ S + ++ I L +GGRV + +D R+L + + ++N ++ + GK P + DY+ I L P F + +N+D S + Q ++L FD I ++ + L N I+ LP++ S PV V ++ERYN+ L + SL +L K +KG ++ E++ ++ LL G+ P W ++ +P Y+ + + K ++ W + ++ + + L F FL Q AR I +D L F
Sbjct: 716 MCIKVIEQIKEFKEHIPMVSILCNPGIRARHWEQMSEIVN--HDLTPNSGTTLRKVLKQNLSAYMEHFETI---SAAASKEFSLEKALQNMVETWDIISF----SHHAHRESGVSILTAVDEIQTMLDDQIVKTQTMRGSPFIKPFEKEIKAWEERLIRIQDTIDEWLKVQAQWLYLEPIFSSQDIMQQMPEEGQLFQTVDKHWREVMRHCVKDPKVLPATSLTGLLEKLQESNNLLEQIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLDFLPNLDIQ---AMYSSEGERVELI-QLISTSEARGAVEKWLVQVEDVMLSSIRDVINRSRLAYPETKRSQW---VREWPGQVVLCTSQMYWTQEVHEAIRSG---------VGGLKNYYNQLQSQLKDIVELVRGKLPKQTRTTLGALVTIDVHARDVVMEMIEKGVSHETDFQWLAQLRYYWNNDNVRVCII---NCDVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIEMKLEFFDFEGTELRLNPNCFVA--ITMNP---GYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNAKPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNL----KLKFPDENEDI------------LLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGISLPAADYQLFLDCAQECCKKHNVQPVKVFLDKMIQTYEMMIVRHGFMLVGEPFAGKTKVLHVLADTLTLMNERGYNDEEKVQYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFREYASAETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSNQMSLIFEAMDLSQASPATVSRCGMIYMEPSQLGWLPLVTSWLNTLPQPLQTQENSTLLLELFNWLIPPALRMLRKNCREVVSTTNSNTVVS-LTRLFEMLLTEPVTEEPGNKNIRTWIMAAFAFSLVWSIGGSCDRDSRERFDQFLREILSGKLEEHPIPAAVSKWECPFNDK-GLVYDYSYEFKGKGCWIHWNESIKNVTLGDKNTKVQDIIVPTIDTIFCTLFTTLIIFFSPFRPLLFVGPTGTGKSVYVKEKLMNNLNKERYLPFFINFSARTSA-------NQSQNIIMARLDKRRKGVFGPPMGKKCIIFVDDMNMPAMEVFGAQPPIELLRQYFDHGNWYDLKDTSKITLVDVQLI-SAMGPPGGGRNAVTPRFLRHFNICSMNAFSDDTMSRIFSNVVAFYLRNNDFPNDCFSIGNQI--VAATL-EVYKKAMENLLPTPAKSHYTFNLRDFSRVVQGCLL--LKKESLENKRTMIRLFVHEVFRVFYDRLVDDQDRDWLYKLMKNIVKEHFKESFDTVFEHLKLCEEDMRSLLFGDYMTPDVEASERLYAEVPSMESFSQVVESYLTEYNQTHKNRMNLVIFRYVLEHLSRISRVLKQPGGNALLVGVGGSGRQSITRLATFMADMTLFQPEISKNYGMNEWREDLKLLLKKAGVKGQKTVFLLTDAQIKEEAFLEDVDSVLNTGEVPNLFAVDEKQEIMEVMHAVRPIA-QAGNKSLEFSPLALFAFFVNRCRENLHVVVAFSPIGDAFRNRLRQFPSLINCCTINWFQPWPEEALERVANKFLETLEMSDHER-QEVMLICKTFHTSAIHLSEKFLS--ELGRHNYVTPTSYLELIAAFRLLLTNKRDTVMNAKKRYTNGLDKLAFAESQVGEMKKELVDLQPKLEQAKIDNIKMVQVIEVESVQVEAKSKVVRVEEEAASQKAAEAQAL----KNECESDLAEAIPALEAALSALDTLKPSDVTIVKSMKNPPSGVKLVMAAVCVMKDIKPEKINDPAGTGQKILDYWGPSKKLLGDMNFLRDLKVYDKDNIPAPVMHKIRSEYMT--NPDFDPTKVAKASSAAEGLCKWITAMEVYDRVAKVVAPKKANLIVAQQSLAATMALLNQKRAELKEVEDRLAALKKTLEEKTEEQAQLQFQVDLCARKLERAEKLIGGLGGEKTRWSKAADDLQNTYDNLTGDVLISAGVIAYLGAFTAGFRQNCTKEWTKLCKSKNIPSSDDFSLSKTLGDPIKIRAWNISGLPTDSFSIDNGVIVSNSRRWPLMIDPQGQANKWVKNSERENNLNVIKLTDADYMRTLENCIQFGTPLLLENVGEELDPSLEPLLLKQIFKQGGMDCIRLGESVIEFSSDFRFYITTKLRNPHYLPELATKVSLLNFMITPEGLEDQLLGIVVAKERPELEEERNALILQSAANKKQLKEIEDKILETLQSSEGNILEDESAIQILDSAKIMSNEISKKQQIAEKTELKIAESREGYRPIAKHSSILFFSIADLANIDPMYQYSLNWFVNLYINSIQDSNKSKILEKRLRYLINHFTYNLYCNVCRSLFEKDKLLFSFLL---CSNLLLAKKEIEYAEFMFLLTGG-VGLQNNVPNPDPNWLQ-DKSWDEICRASDLPGLQGLRYPPFCHFLPIYDSKEPYNTPLPKPWCDKLSDFQKMIIYRCLRPDKIEPAISNYITGKLGKKFVEPPPFDLSKSY-NDSNSTIPLVFVLSPGADPMASLLKFANDKNMGGANFKSISLGQGQGPIAVKMIQSAMKEGTWVCLQNCHLAVSWMSTLEKICEDFSPETCHPDFRLWLTSYPSPMFPVTILQNGVKMTNEPPTGLRLNLLQSYLSDPVSDPQFFSACSNKELVWEKLLYGVCFFHALVQERKKFGPLGWNIPYGFNESDLRISIRQL-QLFVNSYEEVPFEAITYLTGECNYGGRVTDDWDRRLLLTILADFYNKDIIENPRYMFSPSGKYYSPPKSIYEDYVEFIRNLPATQHPEVFGMHENVDISKD-------LQQTKLL---------FDSLILTQGGGSKGGASSGGDSTLMDIANDIRTKLPENFNIDSALNKFPVLYEESMNTVLVQEMERYNN--LCNTIRVSLQNLLKAIKGLVVMDAELEAIAGSLLVGKVPEKWAKRSYPSLKPLGSYITDFLTRLKFLQDWYDTTKPN-----VFWLSGFFFTQAFLTGAMQNYARKYSIPIDLLSF 3783
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000600.1 (pep scaffold:Pmarinus_7.0:GL477903:500:65413:-1 gene:ENSPMAG00000000525.1 transcript:ENSPMAT00000000600.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 2566.19 bits (6650), Expect = 0.000e+0 Identity = 1255/2533 (49.55%), Postives = 1749/2533 (69.05%), Query Frame = 3
Query: 1815 VRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQ--WNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLL-----DQNCQSVTEWEWLKQ--LRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQN----RLVTYSYECEEELSIDQLMSDKKIL----TPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSD---NTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXX--XXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLAS------GEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPK 9329
VR LS LGY I V+ AA KFY A LKQVA FYNTI+ QMIP Q+ M+L+AA+ FEK++K GS+++ + VQ W++PE+L +I +LQ+A+ ++ QNR LR+ H +C+K+V LM +DLLRQQQ+WK + EIR + E +N PW H DHQLYKALE QY GLE L+ +LP+I +L + QGRLQ P EE++S+Y++E+++F+ P F G+ + G IFP+++ERN F+ Y +AE LF RL+ F+EW++LG +D+E +++H + D+E+NF+++KT+GK+AE+LP ++K+DCI VNC P++ S+DT IQ +F+ LL+SLR +I+ + ++A+++ + LS +PQ ++EI +A HA+ ++ + E N LLR+V G G++ +S L+ +WD F+L + + +++++EQ++ M+ +++R +D+ +F+ RW L+P L+S A L ++ +++++ EL EL+ + L DC HF +E L++E+ D+ Q + MW Q+EE+ T L ++ KEDW+SFRSR ++FEEFL W E+LR A T + IRLQ ++D Y+ ++P+LK++RGE LS DHWLE+FRLL +PRG TLE LT HIL++ I++HA +KELN +AQGEV++REA+RELELWGA A F L E+ + + S+ ++ EWRD++ Q+ D + LLQSL+DSPYYR F+DK VWE++L+DLDE L NLN IQRKW+YLEPIFG+ ALP+E +RF RV DF IM +V+R+ R+L+L + G+K LS M+DQLQRCQKALN++LEEKRS FPRFYFIGDDDLLEILGQ+TNP VI++HLKKLF GI+ V+F+ HI+ M+SLDGE+V LR QV +T++VE WLG L EM+ TL L L+ N + I+ +YPSQ+LCL+E + FT E L + L+ EL +K+ YT + +A T S + + + D +L D + V W +Q ++ SKD C + ++D Y + +GNA +LVHTPLTDKCYLTLTQGM MGLGGNPYGPAGTGKTESVKALG LFGRQVLVFNCDEGIDV+++GRIF+GLVKCG+WGCFDEFNRLEE VLSAVS QI IQD +K + TLL +V +D NS IFITLNPAGKGYGGRQKLPDNLKQLFRPVAM+RPDN+LIA VIL+S+GF +A LG KL AIF+L++E+L+PQQHYDWGLRALKTVL+G +LL+ + + + D E+ L+V+ALRVNTLSKL +AD F++L++DVFP D+ +E+ L +A+ E + + Q +K LE++EQLRQR GVV+VGPSG+GKST+W LLR+AL ++G+TV + +NPKA+PR QLLGH+D+DTREW+DGVLT SAR VV++PQ++QSW++CDGD+DPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLS ASPAT+SRMGMIFLS E TDV++LV SWL +QDE + L +++ FY++L W+ K++E + S VG V +GLS+L + ++ HF+V L++GLG NL +R FA V+ E P+ + L+ + + + RL Y + ++ + P++LTA +R LD F WL+ QPF+L GPEGCGKS +L F +L+SV+V T+HCSAQT P HVLQ L QAC +++S +GR RP++ ERL+L+LKD+NLP+ DKWGTSQL +FLQQV+TY+GFYD LE+VGL+GVQ+V SM + S GR LS R +SI+R+ I YP ++L + AYL VL + P HP+W + VK LA +M+ +Y Q+++KFT DD++HYLFTP +LTQW L LLRYD P + D ++A ++LE+ +YES R F+DRLV S AR D L + +HS+W L D ++VTWG+ + P G+ LG+L+S LK I +GL+ ++RE R L ++LF E+ VA+ +RVL++PGGS+LLAG SGVGRRT + L + MH + L+SP++ R Y KQF+ D+K +Q AGVEG + LLLED Q L P++LE++NSLL+S GEVPGL++ EELEP+L L++ A++ G G + NYF R++ LH++L+MD ++ +F + C SNPA K C+V W++ WS+ +MLKIP M++++ + T+ +L G L FL +H++C +T R Y+ F++ Y + + R+ H+Q G+ K++EA+ +V ELK +AAEQS LL EK+ +AD+AL+ IT+ MQ + +K EME+L +E V++ +RK AID ELA ++P V +A+ AV I+ LSEIR+LR PPD+IRDILEGVL +MGT DTSWVSM++FL +RG++++I TFD+R ITRE R VEELL R SFDPK
Sbjct: 1 VRQLSALGYTIPPKVLQAATTALKFYRHANTLKQVAHFYNTIDQQMIPSQRPMLLEAALAFEKIIKKSGSRAEGGSTVQVTWDSPEQLESYIAELQRAAETLTGQNRRLRRTHLDLCDKVVALMSVDLLRQQQRWKSAVQEIRHSICTKEQGGVRVDNMAPWLLHWDHQLYKALELQYQAGLERLHLHLPDIHTELTFTQGRLQLRPPIEELRSRYYREVRRFLGAPAAFLGVRGIT-GPTAIFPAMVERNEMRFLAVYMRAEALFARLADACTAFQEWVVLGQVDVEALIEKHLHTVADWERNFRSLKTRGKDAERLPTQLKVDCIVVNCGPVRTSIDTHIQQLFEGLLHSLRGSIQAHVQEMEAFISEGSRSLSTQPQTVEEIGDARRQHADLVARTPQLEPLFMEMEAKNRLLRSVGGAGVERLSVLRGEWDGFQLRLHNHELVLKEQVDRMRGAVMARVTSIARDVERFHARWMQLRPNASALESSDRGAGLRCLESLREQRSELHELLATRAVLVSDCHHFDVEEPNSELIDEVTADVAQYEAMWGQYEEFVTALSDMEKEDWISFRSRCHVFEEFLLTWHERLRKAAPTPVMIRLQSDVDRYRLVVPVLKFVRGEHLSADHWLELFRLLALPRGTTLERLTFSHILNSTDVILQHATELKELNSRAQGEVSVREALRELELWGASAAFSLAEHTEVEGGSVPIVCEWRDLLGQLADQRSLLQSLRDSPYYRGFEDKVQVWESRLSDLDESLHNLNLIQRKWLYLEPIFGRGALPREHARFLRVHNDFCDIMREVSRDMRLLTLVARPGIKRTLSAMLDQLQRCQKALNDFLEEKRSTFPRFYFIGDDDLLEILGQATNPTVIQAHLKKLFAGIHSVEFDDGCHHIMAMRSLDGELVPLRQQVEVTADVEVWLGMLAEEMRQTLKQLLVQCLK-----NGKSGDIDPSQYPSQVLCLAERVRFTGDVERALPALGLSQLEVELREKIQAYTRFTGTHTAVLTPPSSGSVRMSPSVCMSLCVPVTDPVLAKLVNDASKHLVITGLWQQQGVVKCLLTSKDI-CRVMLLDL-IQYNFNIEGNAQQLVHTPLTDKCYLTLTQGMRMGLGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGIDVRAIGRIFVGLVKCGAWGCFDEFNRLEETVLSAVSTQIHTIQDALKCRAHSCTLLGSQVVLDHNSGIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMTRPDNELIAAVILHSEGFTDAHALGAKLCAIFSLAKEVLSPQQHYDWGLRALKTVLRGCGSLLQSSRQEGADKKID----------ESGLVVRALRVNTLSKLAFADVALFDALVRDVFPGTDLGGVEHGELHNALLEACTHAGLAVVDAQVRKALELHEQLRQRTGVVVVGPSGAGKSTLWSLLRMALARLGRTVVQHTLNPKALPRAQLLGHLDMDTREWTDGVLTASARAVVRQPQDVQSWVVCDGDVDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSSASPATVSRMGMIFLSDEDTDVRALVGSWLSRQDEAVRDDLGELINEHFYRALSWVTKQSEQVVPCSLVGVVMSGLSHLHSCSHRTHFAVGLVRGLGANLPPRTRLDFAKEVFGWVGESLPDPRRP--LDVFVSSPASSEPPRLCCYDSDTASAVANATATATDAEEAWGPPPVVLTAHARRALDTFGPWLDERHPQPFLLVGPEGCGKSTLLRQAFSRLRSVRVATVHCSAQTAPHHVLQTLAQACALVSSGSGRALRPRDCERLVLHLKDVNLPRPDKWGTSQLSAFLQQVLTYRGFYDEALEWVGLEGVQVVASMTAGGSSGRHPLSPRLSSILRIACIDYPEAEELQAVCCAYLGSVLHAVAPAHPLWVATASVKKLAGSMLTLYQQVRAKFTPDDHNHYLFTPRNLTQWALGLLRYD-PSSGDRASSSADAVLEVWAYESCREFRDRLVGSRARDTFDAALASVLHSDWGSNPLPQLADAYYVTWGAHHMSVSAPGQPLPQHGQPLGRLSSTDLKSVIKKGLVHFAREYRPLRLLLFPELLAAVARAERVLSRPGGSLLLAGPSGVGRRTAATLAASMHGLSLLSPRVSRTYGSKQFRGDVKGLMQQAGVEGLQVGLLLEDFQMLSPEFLEIVNSLLSSGVFASIGEVPGLFSPEELEPLLAPLRESASQDGFTGPIYNYFTRRVQQNLHVVLVMDYTHPDFTLKCDSNPALVKRCAVLWMDGWSKQTMLKIPEMMLSEEEEVGSEEKTKERLG---KLPGGAELIRAFLHVHESCAALGATPRRYLAFVQRYQHVLTHTSTALIHRKGHLQAGVSKLTEARTLVDELKGRAAEQSTLLAEKRADADQALRDITTSMQNVSVQKAEMERLQETILQEAVLIEQRKCAIDLELAEVQPLVDEAKQAVGSIRPESLSEIRSLRMPPDIIRDILEGVLRLMGTFDTSWVSMKSFLARRGVRDDIVTFDSRSITREIRDSVEELLMRNATSFDPK 2509
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Sea Lamprey
Match: DNAH6 (dynein axonemal heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:2951]) HSP 1 Score: 1186.02 bits (3067), Expect = 0.000e+0 Identity = 891/3385 (26.32%), Postives = 1624/3385 (47.98%), Query Frame = 3
Query: 3378 EHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLS----------FRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDF----------NKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFT---ARCEELLNENN---IITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLAL-----------NKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWL-----KKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYN------------GLSNLKAIKNK------AHFSVCLIKGLGGNLNENSRETFALWVY----ELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKI--LTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLK-SVQVTTLHC--SAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEF--------VGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVD-----DYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTS-EYLKDTIDRGLLQYS-RECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANES----GHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGS-QLTQNSAK--PKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATE-RKGEMEK---LTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKT---GL---EKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMS------HCCRPDLFKPQEWELF-TGTFISDKSDRNITVPKWIDADRTVAISNLASAMP-------ELWSV--------LNIK-DDDLWHQFAK------SSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKP-----HKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTR-ANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKR---DYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQ-LRILQRFSVHGTKFDKDIWSREL-NPVLNRW-KILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPF-DYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF------VCRWGGSNVSAKYSVKIG-----NLHI----EGCLFDGTMITECNRDSNSIVLL--------PPVSVGWVDKNQPNSYSEDDMISLPIYYDILR----------DKIVTKIDIPCQSGQQDKWIQSGVALFLK 12989
++F++E F L E+ ++ + Q+MW +E++ + ++WL S + + + Q + L + + L+K+++ ++ +P++ ++R L HW + ++ P LTL +++ E+ +AE I++++ +A GE ++ ++++E A F ++ + DS++ + ++ +I + D+ + ++ S Y + + W+ +L ++ L+ QR W+YLE IF + LP E F +VD+ ++ IM + R L + G+ + L++ QK L YLE KR +FPRFYF+ +D+LLEIL Q+ NPQ ++ HL+K F I ++F I+ M S +GE V L + VE+WLG + M +L A+ + + ++ + ++ PSQ++ + + +C E + ++ + +KE ++LN + L + +H + +LI VH DI+ ++ + ++ +EW +QLR+Y + CV +M +++ Y YEY G P+LV TPLTD+CYL L + + LGG P GPAGTGKTE+ K L Q +VFNC +G+D K MGR F GL + G+W CFDEFNR++ VLS ++ Q+ I++ KV R + + A FIT+NP GY GR +LPDNLK LFRP+AM P+ LIAEVIL S+GF++++ L RK+ ++ L E L+ Q HYD+G+RA+K+VL A +L K + E+V ++++ALR + L K D + F ++ D+FP ++I +Y +L S+IE +K + + ++ K++++YE + R GV++VGP+G GK+T++ L AL N Q V V+NPK+I +L G ++ T EW DG++ S R V + E WI+CDG +D WIE+LN+VLDDN++L + + ERI+ P ++ IFE DL ASPAT+SR GM+++ SE V +W+ K ++ Q++++ + +++ L ++ K+ + ++ V G +LK ++ F C + +GGNL EN + F +V E D K P + ++ +YY + RL + E + +K++ L+ T D R Y L + + + +G G GKS++ K++ Q L+ SAQT+ + + + + +R+I+++ D+N+PKLD++G+ I L+Q + GFYD F +Q C+ + R S++ L S PS+ L I+ A +L + P+ VK +A ++E ++ + + + SHY+F DL++ + +L+ D D + + +E R+F DRL++++ + + +L ++ V+V+ +FV + LT E LK + L Y+ +++ ++ F++ ++V ++ R++ + G+ LL G G G+++ + L HM + ++ RGY F DL+ AGVE + V L D Q + ++LE IN++L SGEVP L+ +ELE +L + + A E+ G+R + +F +R++ LHI+L M F C+ P+ C++ W QW R+++L + P + GS +L +N ++ + ++ ++ Y+ +L ++T Y+ I +Y+ + +K++++ ++ I+ G+ K+ E E+V +L+ + + +L +K + + ++K+ + + A + R+ ME VK E + A + +D+ L P ++ A A+ + SD+SE+R PP+ +R ++E + +++ + W S + LG + + +D I+ E IQ ++ KD F P+ +R S A + WV+A YS L+ + P + L+ + D ++ + V+ + + F+ A+ L + +S A L L +E RW + + + E++ + +A+A V Y + R+ + W+ + G+ F + L E +W +GL D +S EN +++ +G P +IDP A W++N L+I+ D NF LE ++R G ++++E+ + L+P L P+L G R +++LGD +DY+ +F+ ++ T+ P P+ V+ +NFT TK+GL+ QLL+ ++ KP+LEE++ L+ K +L +E+ +L+ L + GNIL+N++L+ +L ++K +S I L+E+ + ++ R+ + P+A GS ++FVI+ LS+I+ MY++SL F +LF + TSE +D R L+ Y + R +F+ +L+F+ + H D EW LF G DK W+ +L +P E+ ++ L I+ + + W K E EI +LS FQK++++++ +++ A++ F + L + ++L +Y+ + S P++ ++S G+DP Q + ++ SER + +++GQGQ I L+ + ++GDW+ L+N HL SW+ +E+ + +L H ++RL++++ P F +LQ+S+K+T E P G++ N+ R++ + F K G +F + +FHAIIQER+ F P GW YEF+ +D +L+ + + I W + + +GGRV + +D R L + +KR+F+ + G Y + A+ ++ D+ I L + P F + +N + + QR + ++ L + R S G D +EL + +L + +IL+ + D R ++ + V+ +++R+N+ L++ + SSL +L K + G ++++E++ + L Q P +W +P +++ L L+ ++ W + + F P FL Q AR + +DEL F V R S A + + G ++ + +G L G + D +V+ PP+ V + Q N + + P+Y R V + IP + D WI G AL +
Sbjct: 823 KNFKVEVTNFDALNEVCDELKRKQMMWDSLDEWE-----VFTKEWLECQFETLDPEQLNSEVAKYAKIVNQLEKGLPPNNVVPL---LKKKVEFIREKLPVVAFLRNPSLKARHWEMLEEIIGAPLRDKETPLTLAGLIEL--EVFHYAEQIQDVSGQASGEASLESILKKVEDGWKTAEFVVLPHRDSKD--VFILAGTDEIQILLDDSIINISTITSSRYVGPIKSRVDEWQRQLLLFNQTLEEWMTCQRNWLYLESIFSAPDIQRQLPAEAKMFMQVDKSWKDIMRKIYRLPNALRAATQPGLLDTFKNNNALLEQIQKCLEAYLESKRVVFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDAIARLEFALAPAEGEQERTFTNDILAMVSPEGEKVSLGKGLKARGNVEDWLGKVEEAMFQSLRRLTKMAIGEYQSMPRTEWVVSG--LPSQVVLTVAQLMWCRDLTQCLEGGDHDHLQSVANFEKENFERLN----SLACLVRGNLPKIHRCIITALITVDVHARDIVTDMVQEKVETANNFEWQRQLRYYWDLELDNCVARMALSQYVYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKVPRFMFEGREIKLIQTCAAFITMNP---GYAGRTELPDNLKALFRPIAMMVPNYALIAEVILYSEGFESSRVLARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSL--------KRENPHLREDV--------VLIRALRDSNLPKFLADDAMLFSGILSDLFPGVEIPNHDYGSLQSSIENALKARKLQAVPSMVHKVIQLYETMLVRHGVMLVGPTGGGKTTVYTALSDALGSLHEAGESKHNPFYQKVHTTVLNPKSISMGELYGEVNNLTLEWRDGLMALSVRVAVADDSEDHKWIVCDGPVDALWIENLNTVLDDNKMLCLANSERIKLTPQIHMIFEVQDLKVASPATVSRCGMVYIDSEELKWMPYVQTWMNGIIDKFGEDTGQYIMALF-ENYVEDGLRFVNKKCTQAMPQVDISKVTTLSCLLESLLLGKGGPDLKMEHSRLTSIVCQTFVFCYLWAVGGNLVENCWDQFDTFVKHQFEENHDAKLP--SSGDLWSYYMDYDSKRLDPW------ERIVPNFRYNKEVPFFEMLVPTTDTMR-FGYLMEKLLA-VKHSVLFTGTTGVGKSVVARGLLDKIQEEAQYVPLYINFSAQTSSTRTQEIIESK---LEKKRKNIIGAPGKKRVIIFVDDLNMPKLDRYGSQPPIELLRQYQDFGGFYDREKMFWKEIQDAREDRGAMQPFCAPPGGGRNPVTPRFIRHFSMLCLPS---PSEHSLKQIFQA----ILTGFLVDFPV-----AVKQVATNIVEAAVEMYGRMSTELLPTPAKSHYIFNLRDLSKCMQGILQCDSGTVRDQNQI--FRLFCHECQRVFHDRLINNEDKDYFNTMLAEMASKQFGVQVEAE----YFVKHPILFGDFMKVGVQRADRVYEDLTDVEKLKGVLQDYLDDYNLSSAKEMKLVFFQDAIEHVTRITRMIRQERGNALLVGVGGTGKQSLTRLACHMCGYRCFQIELSRGYSYDTFHEDLRKLYTIAGVEDKDTVFLFTDTQIVIEEFLEDINNILNSGEVPNLFEKDELEKVLAATRPKAKEAGIPEGNRDEVLQFFINRVRARLHIVLCMSPVGDAFRARCRMFPSIVNCCTIDWFVQWPREALLSVSKTFFT--PVDLGSDELKENLSEMCVEIHMSVTELAEHYYAELRRRY---YTTPTSYLELINLYLSMLGEKRSQLTNSRDRIKNGLTKLLETNELVDKLQLELSALEPVLKQKSEDVEALMEKLATDQENADQVRRVVMEDEAVAKVKAEETQAMAADAQRDLDEAL----PALQAANRALDSLDRSDISEVRVFTNPPEGVRTVMEAICIVL-SKKPDWASAKQLLGDSNFLKRLTDYDKENIS-EDVIQKLKVYINNKD-FVPEKVERVSKACKSMCMWVRAMDLYSRVLKDVGPKRQRLATAQAELDATMAMLNDKQRRLKQVEDQIGALQDQFDMSVAEKESLAKNMALTQARMSRAGKLTSALGDEQIRWQESVAQFQVEINNVIGNVFIASACVAYYGAFTSHYRQMLIDRWISRCQELGIPINANFSLIGILGDPFEIRQWNTDGLPRDTVSTENGILVTRGRRWPLMIDPQDQANRWIRNKEMKNGLKIIKLTDGNFLRTLENAIRLGMPVLLEELKETLDPALEPILLKQTFVSGGRLLIRLGDSDVDYDKNFRFYMTTKMANPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPELEEQRNELIVRINADKNQLKVIEDRILKLLFTSEGNILDNEELIKTLQESKVTSGAIKTRLKEAEATEEMINTAREKYRPVAARGSVMYFVIASLSEIDPMYQYSLKYFKQLFNMTIETSEKRSDLAERLELLLKQTLLATYTNISRGLFEQHKLIFSFMLCIEILRQHGHVSD----AEWNLFLRGAAGMDKERPTKPEIGWLAESTWNLCCDLEDHLPCFKGLKREIVAIPILVTLGRLEIRLNPEAWEGCMKEPLHFTEEVSENEIQGHWNERLSKFQKLVLVKSFMEEKVVFAMTDFVIENLGKAFIENPPVDLATLYQDMSAST-PLVFVLSTGSDPMGAFQRFAREMGYSERVHAISLGQGQGPIAEKLIEEAVKSGDWVFLQNCHLAASWMLAMEEIIKALSEPNAVIHPNYRLFLSSMPTRNFPVTVLQNSVKVTNEPPKGLRANIRRAFTEITPAFFEKNVLGQNWRKIIFGICFFHAIIQERKKFGPLGWNIHYEFNDSDRECA--LLNLNLFCQDGRIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPKTLE-PGYLYSTSGIYYASEEKTLQDHKDYIENLPLNDDPEIFGMHENANLAFQRQETGTLVKTILEVQPRSSGQGAGTSNDEIVKELADSILAKLPEILDMEGAMESLFTRDEKGRINSLTTVLE-QEVDRFNT--LLQVIRSSLHTLKKAIAGFVVMSEEMEKIYNSFLNSQVPVLWSDNAYPSLKPLGGWVKDLALRTTFIDAWIKTGPPKSFW-----ISGFFFPQGFLTGTLQNHARKYNLPIDELGFHYKTLPVYRDQTSVAEAMRTQQFGQELEADIQLPAVQDGVLVHGLFMDASRWDDEDMVMEDALAAQMNPPLPVLHFEPCQ-NYQPDPSLYHAPLYKTSARAGTLSTTGHSTNFVVTVFIPSKR-DSDYWISKGAALLCQ 4108
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006497.1 (pep scaffold:Pmarinus_7.0:GL476875:373:73185:-1 gene:ENSPMAG00000005847.1 transcript:ENSPMAT00000006497.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 748.043 bits (1930), Expect = 0.000e+0 Identity = 610/2399 (25.43%), Postives = 1092/2399 (45.52%), Query Frame = 3
Query: 2745 KEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLR----TVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSG-STQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDW------------LSFRSRYYLFEEFLTQW--FEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIF--GKNA--LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLC-SMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFN-KDIQHIITMKSLDGEVVELRNQVLIT----SEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERR-VNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAH--------------FSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEK------QNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKS-VQVT-TLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY--DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAY--------------LKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLN-DVWFVTWGSREXXXXXXXXXXXXKSLGKL-----TSEYLKDTIDRGLLQYSRECR--DLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSL-----KDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQN--SAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVI--LAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIM-------------GTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCK-DSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLEN-----------EQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISA 9611
++ + LP + + P+K+++ + A +L + + D V A+ K L++ ++++ A AE ++ S I E+ +L T D V L W Q + MK ++L+ +F +D+ F + PG ++G + Q D +Q + + +L + E E F + ++ L+ I +++ Q ++ + + + W L F+++ + L +W FE L+ K+ID + + P+L+ + + + HW + + + + L++I++A ++ + I+++ A E I ++ + + F + S+ + + + ++ + D+ +L SL + Y F+ W KL++ E ++N +Q W+YLE +F G A LP+E RF+ +D+ ++ IM + ++ C + LL +++QL+ CQK+L YLE+KR +FPRF+F+ D LLEILGQ+++P I++HL LF + V F+ K+ + I++++S +GE V L V+ VE WLG+L +++T+ + A + + +P+Q+ L++MI L N N + +K N + ++ +K ++LI VH DI D L+ N +S ++EWLKQ RFY + C+IQ+ D +F+Y EY G +LV TPLTD+CY+TL+Q + M +GG P GPAGTGKTE+ K +G G+ V+VFNC + +D + +GRI+ GL + G+WGCFDEFNR+E VLS + QI I+ KNK + + V +D IF+T+NP GY GRQ+LP+NLK FR VAM PD +I V L S GF++ + L RK ++ L E L+ Q HYD+GLR + +VL+ T G N ++ E ++++ LR LSKL D F SLI D+FP I + + Y L AI K +V K++++YE R R G++ +GPSG+GK+ +L A+ G+ + MNPKAI Q+ G +D+ T +W+DG+ + R+ +K + WI+ DG +D WIE+LNSVLDDN+ LT+ +G+RI PN +FE H++ ASPAT+SR GM+F+SS D + +V +WL+ +L + +D F ++++ + + + LK + +A FS+ G L + +R L + + N ++ Y + R+ ++Y D + IL P ++ F + ++ +L G +G K++M+ K + + +T +L+ S+ TTP ++ Q+ ++ ++ G Y P ++ +++ DIN+P +++WG ++Q++ GFY + EF + VQ V +M R + + + PS ++ I+ + + + L+P Q +KVK+L +KF HY+F DL++ +L + V + LL + +E +R+ DR + + +G + + + S+ +V+FV + P+ G P K+ + L + + L+QY+ R ++D++ F + ++ K+ R++ P G+ LL G G G+++ + L S + + R Y + DLK + G +G+ + + D++ + +LE +N++LASGEV L+ +E++ I L K+ +L +YF R++ LH++L F PA C++ W + W RD++ + + + E ++ + A Q ++ YF + T + Y++FI Y IY +K + + ++ G+ K+ EA++ V++L + + K L AD+ L ++TS Q A K +++K VK + ++ +A KA + +L +P +++A A+ IK +D+ +R L PP +I I++ VLL+ M SW + + G + TF I E V+ L+ + + ++ + A+ A L +W KA V + +++ PL+ Q +L R ++K ++L+ + D AV ++ + DA ++ NA I
Sbjct: 1151 QQVQDLPAHFAVGPVLAMTEPLKLALVQECRTWKRAFGAALNRKASASTDEVLAFSEAMAKHLARPICDLEDVRAAMAALAELRAAEIQMESAIGPVEEAFAMLAKYDLTFRDSSADRVDGLAYCWKNLMTQSVQVQNTLVILQPTMKADLLTGVAEFHKDLSSFQLDYDTQGPG----EAGIAPQEASDRLQMCQMQFDDLWRKFTTYSGGE---ELFGLPVTDYPELQRIRRELALLQKLYGLYNTVIESVDGYYEILWSDLDIEKINNELLDFQNKCRKLPKALKEWQAFEDLK------------KKIDNFNETCPLLEMMANKAMMSRHWERITNVTGHTFDIESDHFALKNIMEAP--LLTFKDDIEDICISATKERDIDAKLKAVVSEWSSQCFTFAPF-KSRGELLLKGSDTAEKVALMEDSLMVLASLMSNRYNVPFKPTIQQWVQKLSNTTEIIENWMMVQNLWIYLEAVFVGGDIAKQLPQEAKRFQNIDKSWQKIMQRAHEIPGIVVCCVGDETLAQLLPHLLEQLEMCQKSLTGYLEKKRLVFPRFFFVSDPALLEILGQASDPHTIQAHLLGLFDNVNQVGFHEKNYEQILSIESQEGESVTLVEPVMAQRGWQGNVETWLGSLLTGVRSTVHAVIRQAAAIIEDGAFKLHEFQTS-FPAQVGLLAQMIWTRDSEVALNNAKNDRKIMPATNQKFLDLLNELIDMTTRDLTKRERVKYETLITIHVHQKDIFDDLVRMNIKSTADFEWLKQSRFYFVEETDKCLIQITDVDFHYCNEYLGCTDRLVITPLTDRCYITLSQALGMSMGGAPAGPAGTGKTETTKDMGKCLGKYVVVFNCSDQMDYRGLGRIYKGLAQSGAWGCFDEFNRIELPVLSVAAQQIYIVLQCKKNKRTQFVFTDGDIVEMDREFGIFLTMNP---GYAGRQELPENLKIQFRTVAMMVPDRAIIMRVKLASAGFRDNQILSRKFYTLYKLCEEQLSKQVHYDFGLRNILSVLR--------------TLGAVKRSNPEEP--EKTVVMRVLRDMNLSKLVDEDEPLFMSLINDLFPGITLDKAGYPELEEAILAQTKAAGLVHHPPWVLKIIQLYETQRVRHGMMALGPSGAGKTCCIHMLMKAMTDCGEPHREMRMNPKAITAPQMFGTLDVATNDWTDGIFSTLWRKTLKAKKGEHIWILLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMSSSVLDWRPIVQAWLQGLPTEQAQVLWSTMDSVFQDLINFVFTAVNPKMDILECMYIKQAIELLKGLLPEADERRLEHSHLQRLLVFSLMWSVGALLELEDRARMEAFLRAHPSHLDLPGSANDDSIFEYVVGDSGGWEHWNTRVPEFAY------PRDTVPEYSAILVP-----NVDNVRTDFLMQCIMKQEKAVLLIGEQGTAKTVMIKGYMNKYDAELHLTKSLNFSSATTP-NMFQRTVES--YVDKRMGTTYGPPAGRKMTIFIDDINMPIINEWGDQITNEIVRQLMENNGFYNLEKPGEFTTIVDVQFVAAMIHPGGGRNDIPQ-RLKRQFCIFNCTLPSNASIDKIFRTFAEGHFCPERGFPEEVNQLAVALVPTTRRLWQATKVKMLPT---------PAKF------HYIFNLRDLSRIWQGMLIMNSEVCRSSDM--LLALFGHECVRVIADRFTAQQDKDWFNGTMSKIMLDDHGTAAAASMEAEVYFVDFMRDAPEPTGEEPDDADLEAPKVYEPIPSFPQLAERLQAFLVQYNESVRGANMDLVFFADAMVHLIKISRIIRTPRGNALLVGVGGSGKQSLTRLASFIAGYSSFQITLSRTYNMSNLMEDLKQLYRKTGQQGKGVTFIFTDNEIKDEAFLEYMNNVLASGEVSNLFARDEIDEITQELIPVLKKEHPRRPPTNENLYDYFLSRVRANLHVVLCFSPVGEKFRARALKFPALISGCTMDWFQSWPRDALTAVAGHFLAEYRVECTPEVKRGVVDAMAVFQDMVAERCVEYFERFRRQT---YVTPKSYLSFIGGYKSIYSEKLSNVALLSERMRTGLSKLQEAEKSVSQLSRELEVKEKELAVASRRADEVLCEVTSKAQAAESVKQQVQK--VKDKAQAIVDEIAADKAVAEKKLEAAKPALEEAEAALQTIKPADIGTVRKLSKPPHLIMRIMDCVLLLFRRRVDTVVPEPERPCMRPSWSEAQKLMNFAGFLNSLLTFSKDTINEE---MVDLLMPYMEMEDYNLETARNVCGNVAGLCSWTKAMVTFFGINKEVLPLKANLIIQESRLAVAQGELDRAQAQLDEKQRELDAVQAMYDTAV----REKQILVDDAEACRRKMNNATALIDG 3463
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001140.1 (pep scaffold:Pmarinus_7.0:GL478666:370:47701:-1 gene:ENSPMAG00000001005.1 transcript:ENSPMAT00000001140.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 732.25 bits (1889), Expect = 0.000e+0 Identity = 591/2164 (27.31%), Postives = 1023/2164 (47.27%), Query Frame = 3
Query: 3606 RLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGK----NALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNK--DIQHIITMKSLDGEVVELRNQVLIT---SEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQ-ILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQ-------TVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQ----DEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTV-------------YNGLSNLKAIKNK-------AHFSVCLIKGLGGNLNENSRETFALWVYELTDE-----------------------KTPEMNKQNVLNYYF-NEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKL---KSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYD-SNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLND--IYTAYLKPVLKRLIPKHPIWSQNSKV-KLLANTMIEVY-SQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHS----------------EWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANE-------SGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQL--TGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSK-AAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGE----ENVILAKR-KAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGT--------------MDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVE-ELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYM 9740
+L+ ++ ++ +P+ + + GL HW + ++ P LT E + L L+ E +++ A E ++ +A+ ++ F L+ Y DS + +S + DI + D+ Q+++ SP+ + F+ WE KL L E L ++Q W+YLEPIF +P+E RF VD+ +R ++ + VL++ S+ M L + L+ K LN+YLE+KR FPRF+F+ +D+LLEIL ++ +P ++ HLKK F+GI V+F + DI H MKS +GEVV+L + + +VE WL L M ++ + + A++ + ++ + +P Q +LC+S+ +T+ E + + + + + N + + L + L +L++ VH D++ LL ++++WL QLR+Y + D +M++A Y YEY GN P+LV TPLTD+CY TL +++ LGG P GPAGTGKTE+ K L +Q +VFNC +G+D ++G+ F GL+ CG+W CFDEFNR++ VLS V+ QI IQ GI + + ++ A+FIT+NP GY GR +LPDNLK LFR VAM PD +IAE++L S GF +A+ L K+VA + L E L+ Q HYD+G+RA+K+VL A NL K K ++ D L+++++ L K D FE + D+FP + + + +Y L AI+E ++ N+ +K+L++YE + R G +IVG GK+ +++L AL I + V+ V+NPKAI QL G D + EWSDGVL S R + W++ DG +D WIE++N+VLDDN+ L + SGE IQ N IFE DL ASPAT+SR GMI++ + L+TSWL + + L+ + L ++ K + TS+ V ++ + +KA+ ++ F L+ +G + + + + F + EL P +V Y F E + R ++ I + M+ I+ P T D R ++ + Q+P + GP G GKS+ + + K + + T++ SAQTT Q N ++ VY P + +R++L++ D+N+P +++G + L+Q + + +YD + + L+ VQI+ GR++++ RF +I ++ +D ++T + + + + + S + + L + +EVY + ++ SHYLF D ++ V+ + LP T A S+ + +E +R+F DRLV R + TIH+ + VE D L + F + + A + L + +L++ S+ + ++++LF+ ++V ++ R+L +P LL G G GR++ + L +HM + +L ++ +GY +++ DLK L+ + ++ V L D Q + +LE IN+LL SGE+P L+ +E + I ++ + + G +L N F DR + LH++L M F + P+ C++ W + W D++ + + + E S+ T S +L T + L+ F + T Y+ I + + KK+ E+ + +VG++K+ A VA ++++ AA Q +L LEA + +V++ +E E++ VK E E + AK K D +LA P ++ A A+ + D++ ++ +++PP ++ ++E + ++ G ++ W + LG + + FD I + + +T + FDP + AS AA L WV A Y + +AP + + NQ + L A ++ ++ + +V +AG ++ E A LE ++ + + AE L+ L E RW + L + LT +L+++ V Y+
Sbjct: 705 QLKSNVEAFRTHLPMAQVLCNPGLRGRHWDALSEVVGFPL-LTQEQVCLEKFLEMNLE--SFLSKFNDISDTASKEYSLEKALEKMVREWDEMQFTLIVYRDSGTSILSAVD---DIQMLLDDHIVKTQTMRGSPFIKPFESDMKEWERKLLLLQEILDEWLKVQATWLYLEPIFSSPDIMAQMPEEGRRFTTVDKTWRDLIKQTLTDTHVLAVVSIDKMLERLQKSTELLELILKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGISRVEFTEALDITH---MKSSEGEVVQLIETISTSKARGQVEKWLLELEAVMIRSVHNVIGEAMEAYPSTPRAEW---VRAWPGQTVLCVSQAF-WTSEVHEAIRGGQQVL--ERYLAQCNGQIDEVVGLVRGQLSQQSRVTLGALVVLDVHARDVLVALLKGGIAHDSDFQWLSQLRYYWE--DGHLQTRMINAGLPYGYEYLGNTPRLVITPLTDRCYRTLFGALNLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYIALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINTGSDTLMFEGTELKLNPTCAVFITMNP---GYAGRSELPDNLKALFRTVAMMVPDYAMIAEIMLYSFGFVSARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNL----KLKYPSENEDI------------LMLRSIVDVNLPKFLAHDLPLFEGITSDLFPGVKLPKPDYVVLLEAIKENCEKMNLQMTDFFAEKILQIYEMMIVRHGFMIVGEPFGGKTCAYRVLAAALGDICEKALMAENKVQITVLNPKAITMGQLYGQFDAISHEWSDGVLAVSYRAFATSTSPDRKWLVFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQLASTTNLIFEPMDLEVASPATVSRCGMIYMEPHILGWRPLLTSWLNARPPPLSAPHKALICALFERLVPCCLQFVRKSTKELSPTSDTNLVCSLMNLMDCQMDDFHDETKIKAMDDRDVSAWIEGIFLFSLVWSVGASCSTHGQVLFDQLLRELMSGPLSADTSKRFHLSENVEPPAEPFSVPFPAAGSVYEYRFIQEGKGRWELWTEALSLAPPIPRDMNFNDIIVP---TLDTIRFTALMEMLVTH--QKPVLFVGPTGTGKSVYITNFLLKHLDKNTYKPLTINFSAQTTAA---QTQNIIMGKLDRRRKGVYGPAQGKRMVLFVDDVNMPAREEYGAQPPVELLRQWLDHSNWYDLKDCSMIKLENVQIL-GAMGPPGGGRNAVTARFLRHFNTVTI-----NEFDDKSMFTIFSRIMGWHFTARFAFPTDFSVLTEQLVQSTMEVYKAATQNLLPTPTKSHYLFNLRDFSR-VIQGVCLSLPETCP-VAASIQRLWVHEVLRVFYDRLVDDADRTWLVAFIRKTIHTYMKEDFTQLFQHDSNGDGQVE-DDDLRSLMFCDFSDSKDDAKRYVEVSDVERLRLVVEGHLEE-----FNNLSK--KPMNLVLFRFAIEHVCRISRILKQPRSHALLVGVGGSGRQSLTRLAAHMADCELFQVEISKGYATNEWREDLKRILRRSTDGEQNGVFLFTDTQIKQESFLEDINNLLNSGEIPNLFAPDEKQEICEKMRQIDRQRDKDKQTDGSPLALLNMFVDRCRDQLHVVLAMSPIGDAFRNRLRKFPSLVNCCTIDWFQSWPGDALQAVATRYLEDV---EVSEETLASCIDMCKLFHTSTIALSQKFQAEQQR--YNYVTPTSYLELISTFKDLLEKKRLEVMRMKRRYEVGLEKLESATSQVAGMQAELAALQPQL-----LEAGIQVVNTMAVIERESEEVSRTERV-VKADEAVANEQAMAAKVIKDECDADLAEALPILRSALAALDTLTQQDITVVKTMKSPPAGVKLVMEAISILKGVKPDRVPDPSGSGRMVEDLWGPAKRLLGDMKFLQSLHDFDKDNIPVAIMKTIRAKYITNLE--FDPDKIRNASTAAEGLCKWVIAMESYDKVAKVVAPKKVKLNQAEAELAVAMGSLRRKQEALREVQDKLAGLQQTLEANKQKKADLENQVDMCTKKLDRAEQLIGGLGGERSRWMEAARLLGIRYNDLTGDTLVSSGIVAYL 2795
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001370.1 (pep scaffold:Pmarinus_7.0:GL479430:457:33677:-1 gene:ENSPMAG00000001214.1 transcript:ENSPMAT00000001370.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 730.709 bits (1885), Expect = 0.000e+0 Identity = 565/2028 (27.86%), Postives = 953/2028 (46.99%), Query Frame = 3
Query: 3951 DIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIF--GKNA--LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLC-SMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDI-QHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELL-NENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERR-VNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKA-IKNKAH------------FSVCLIKGLGGNLNENSRETFALWV--YELTDEKTPEMNK--QNVLNYYFNEKQNRLVTYSYECEE-ELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKL--KSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY--DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDI--------------YTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSS------DARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEY--LKDTIDRGLLQYSRECRD--LDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHN-------IKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRG-----SLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQN--SAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVI--LAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIM-------------GTMDTSW------VSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKD--SFDPKNAKRASIAAAPLAAWVKANVKYSYALEK-IAPLEN----EQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDF---EKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIY 9737
+II+ + D+ +L SL + Y F+ + W + L++ + ++N +Q WVYLE +F G A LPKE RF +D+ + IM+ + N V+ C M LL +++QL+ CQK+L YLE+KR LFPRF+F+ D LLEILGQ+++ I++HL +F I V+F++ + I+ + S +GE V+L V+ VE WL L E + +L + A ++ S S D YP+Q+ L + +T EE L N + + + N +S++ V +K ++LI VH DI D L + +S T++EWLKQ RFY K ++ + D F Y E+ G +LV TPLTD+CY+TL Q + M +GG P GPAGTGKTE+ K +G G+ V+VFNC + +D + +GRIF GL + GSWGCFDEFNR++ VLS + QI I+ K + + T + V ++ IF+T+NP GY GRQ+LP+NLK FR VAM PD +I V L S GF + L RK ++ L E L+ Q ++ +G+ + LK + + H S +++ R ++ K+ D F SLI D+FP I + + Y L +AI +++ +V K++++YE R G++ +GPSG+GK+T L A+ + G + MNPKAI Q+ G +D+ T +W+DG+ + R+ + + WI+ DG +D WIE+LNSVLDDN+ LT+ +G+RI PN +FE H++ ASPAT+SR GM+F+SS D ++ WLK++ ++ L + F + + A F + T + L+ L+ I +K H + L+ + L + R LW+ +E P ++ ++ + Y + V +S EE D IL P ++ F I + + +L G +G K++ML K ++ L+ S+ TTP+ + + ++ G Y P ++L +++ DIN+P +++WG ++Q++ +GFY + EF + VQ V +M R + + + + PS ++ I +T ++ + +L+P Q +K+K+L +KF HY+F DL++ LL V S + LL + +E R+ DR + + R A + ++ V + V F+ + + + Y L+D ++ L QY+ R +D++ F + ++ K VL G L + G +L + + +++P R Y DLK + AG +G+ I L D++ + +LE +N++L+SGEV L+ +E++ IL L + + R +L +F R++ LH++L F PA C++ W +W +D+++ + ++ + ++ Q + Q ++ YF + V T + Y++F++ Y +Y +K E++T N +Q+G++K+ EA E VA L + + K L +ADK LK++T Q A + K E++K VK E ++ ++ KA + +L +P +++A A+ IK SD++ +R L PP +I I++ VLL+ G + SW ++ NFLG ++ F IT E + ELL D ++ A++ A L +W KA + Y + + K + PL++ +Q +L + + + +L+ +++D AGY K ++ DA + +++ A+ IS L E ERW E A++ L L+A A + Y
Sbjct: 49 EIIATMEDSLMVLGSLMSNRYNAPFKSQIQKWVSNLSNTTDIIENWMTVQNLWVYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEMNNVVQCCVGDETMGQLLPHLLEQLELCQKSLTGYLEKKRLLFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKTVEFHEKVYDRILAVCSREGETVQLDKPVMADGNVEVWLNALLKESQQSLHGVIRSAALAVQDSAFSLIEF-LDSYPAQVGLLGIQLLWTRDSEEALANARYNRKAMPQTNQAFLVLLNRLISMTTQDLSAVERIKYETLITIHVHQRDIFDDLCRMHIKSPTDFEWLKQCRFYFKEDVDKLIVWITDVSFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQIAIVLTCKKERRSQFTFTDGDLVEMNPEFGIFLTMNP---GYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFLDNIVLARKFYTLYKLCEEQLSKQVYWVYGILEVMYSLKTCKAMGKAHTSSTAQL----------------FCIRSYRRVSMMKVIDEDEPLFLSLIDDLFPGIALDKAGYPQLEAAINRQVEQAGLVIHAPWKLKVIQLYETQCVRHGMMALGPSGAGKTTCIHTLMRAMTECGSPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTTRAKKGEHIWIVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMSSSVLDWSPILEGWLKQRSPQERETLRSLYAKSFLELYRYAAHSLSFKMDTLEAFVIVQSLNMLQGLIPSKDHGGEVTPEHLGRLYVFALMWSVCAYLELDDRRRMELWLRSHESMRLDLPAVSPHGEDSMFDYMVGADGQWVHWSSRVEEYAYPGDHTPEYNSILVP-----NVDNVRTDFLIHNIAKQGKSVLLMGEQGTAKTVMLKGYLSKYDPETHLAKNLNFSSATTPLMFQRTIES---YVDKKMGTTYGPPAGKKLTVFIDDINMPIINEWGDQVTNEIVRQLMEQRGFYNLEKPGEFTNIVDVQFVAAMIHPGGGRNDIPQ-RLKRQLSIFNCTLPSNASIDKIFGVIGTGHYSAARGFTEGVRALAAQLVPATRRLWQLTKIKMLPT---------PAKF------HYVFNLRDLSRIWQGLLNTTADVVS--SPELLLRLFKHECERVIADRFTCAEDTDWFEERLAAVASEELGAAAGEALAVGERAFFVDFLRDAPEATGDEPEDADFDMPKIYEPIASYDELRDRLNFFLQQYNESVRGARMDLVFFTDAMLHLVKFIPVL----GVTNLTLMTFDGHSLQDILSASLRTDSDPAVLTPVVTPA-SRSYSTSNLLEDLKVLYRVAGQQGKGITFLFTDNEIKDEAFLEYMNNVLSSGEVSNLFARDEMDEILSELAPVMKKQHPRRPPTQENLHEFFMTRVRLNLHVVLCFSPVGERFRTRALRFPALISGCTMDWFSRWPKDALVAVSEHFLSSYTMDCTVEVKQEVVACMGSFQDGVAEKCTDYFQRFRRSTHV---TPKSYLSFVQGYKTVYKEKHTEVQTLANRMQMGLQKLKEASESVAGLSVELEMKEKELQVANEKADKVLKEVTVKAQAAEKVKMEVQK--VKETAERIVDSISVDKAVAEKKLVAAKPALEEAEAALQTIKQSDIATVRTLGRPPHLIMRIMDCVLLLFQRRVNPVRMDPERGCVTPSWQESLKLMTAGNFLGS------LKQFPKDTITEE----MVELLHPYFDMPDYNIDTARKVCGNVAGLCSWTKA-MAYFFGINKEVLPLKSNLVVQQGRLNIAMGDLQSAQAELDAKQAELDLVQAGYEKALREKQELMDDAERCRRKMQTASGLISG-------LAGEKERWTNMSKEFAAQIKRLVGDVLMATAFLSY 2002
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Yeast
Match: DYN1 (Cytoplasmic heavy chain dynein; microtubule motor protein; member of the AAA+ protein family, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p; motility along microtubules inhibited by She1p [Source:SGD;Acc:S000001762]) HSP 1 Score: 854.744 bits (2207), Expect = 0.000e+0 Identity = 688/2561 (26.86%), Postives = 1261/2561 (49.24%), Query Frame = 3
Query: 3549 FLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFR----------LLNMP----RGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCL-LQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVE--NWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWE--WLKQLRFYQKSKD----QGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKI-GQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEP----QEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTY----LDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLG---GNLNENS-RETFALWV-----YELTDEKTPEMNKQNV--LNYYFNEKQNRLVTYS--YECEEELSIDQLMSD--------KKILTP--LILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKES-ERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDS-NLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIIL-IMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKP-------KTQLTGSDNLNSYF-LDLHDTCPVEFS--TSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEME---KLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQV-----EELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQL-------KRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMR--------KFLTTEREQLEWKKEGLSSDELSMENALVILQGI-LIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRA-LNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPK 10925
FL + E R + M L +++M + IL ++ L HW +FR LL+ + + + LTL IL + ++ ++AQ E I +++ ++ + A ++++E+ ++ + L++EW D++ Q L S+K S YY+ F+ E+KL L E N ++Q W+ L I G+N LP E S+F+ + +++ I + + + + + + L ID L+ + +L+ +LE +R FPRFYF+G+DDLL+I+G + + +KK+F I + F +D I ++S++GEV+ L ++ + ++ WL L+ E+K ++ Q L L+ + ++ + KY Q + LS + +T E+ L N KE+ K+ + K++ S+D+ K+++L+++ +H ++I QL +NC + E W K +FYQK+ I Y +EY G +L++TPL + TLT +H GG +GPAGTGKTE+VKA G GR V+VFNCD+ D + + R+ +G+ + G+WGCFDEFNRL+E VLSAVS IQ IQ+G++ ITLLE + ++A+FITLNP GY GR +LP+NLK+ FR +M P + IAE+IL GF+++K L K+V L + HY +GLR LK VL+ + L+ KT +V++L+ L L D + F+ + +F + + + +++ + + KK ++ Y + + +++VG +G GK+ WK + A+ G YV++ K + + L G + T EW DG+ T R+V + + + W++ D D+DPE++E++NSVLDDN++LT+P+GER+ PN +FET +L +PATI+R G+++ S++ + S + L K E + LS + L D S D + N FT S V + G+ ++ +V LI NL++ S ++ L + Y L + T E + + +N YF L YS ++LS S+ +++ P +I T D ++ F LNS ++ IL GP G GK++++N+ + V ++ S TT H+L L++ + ++ G PK + L+L+ +INLPKLDK+G+ ++ FL+Q++ +GF+ + ++V ++ + IV + N + GR +S RFT + + YPS L+ IY Y K + K L+P+ +++ A + +Y++ K++++ SHYLF+P +LT+ V + + T SL+ + +YE+ RIF DRLV + + +L+ T+ + QD L ++ + + ++ L + I+ + E ++ +++ + + D++ ++DR L + G ++L G S G+ + V+ ++ +K++ PK+HR L F LK + ++ L++++ LE +LE +N+LLA+ ++P L+ EE + +L +L++ G L ++F I LH++ I D +N N S+PA F C + W+ W +M ++ +++ IP E + K +T N+ +F + + V + + ++I+ ++ +++ K +++ Q + VG++K++E+ V EL +++S LTEK+ EA L K+ + Q +ERK E K +K EE++ KRK + + IEP + +A+ V +IK L+EIR++ PP ++ ++E V I+G ++W ++ F+ K I +D T + Q+ EE L+ +++ N RAS A PL WV A + +S LE + PL E ++ K NL AE+ +DLE + + + +D E + + ++ N + +IS + L F E ERW + + L ++++ Y E +R + L + K L KF ++ +L T E+++W + GL ++ +EN +++ +PFL+DPSS+ + N++ ++ + +++ + F LE ++RFG +IIQ+ + +P++ L+ + G R V++GD +D + DFKLF+ + +P +P + V V+F T K ++ ++ +T+ +++ ++ +L++ + K++L +E+ LL+EL N+ GN+L N +L+++LN K+ ++ I + L ES + D + + + +H +F ++ + + Y S+ FL F+R + S + + R ++ L + VY ++ K +++ A+ M + D+ + ++++ T I S+ + VPK
Sbjct: 1268 FLRRADELPRAVKQFEMYKSLFSQVNMLTSVNKILVELKDGALKPRHWNMIFRDIGKRQIQKNLLDKLEFSLKDVMVLNLTLNEIL------------LTKIIERAQKEFVIEKSLNRIKKFWKEAQYEVIEH----SSGLKLVREW-DVLEQACKEDLEELVSMKASNYYKIFEQDCLDLESKLTKLSEIQVNWVEVQFYWLDLYGILGENLDIQNFLPLETSKFKSLTSEYKMITTRAFQLDTTIEVIHIPNFDTTLKLTIDSLKMIKSSLSTFLERQRRQFPRFYFLGNDDLLKIIGSGKHHDQVSKFMKKMFGSIESIIFLEDF--ITGVRSVEGEVLNLNEKIELKDSIQAQEWLNILDTEIKLSVFTQFRDCLGQLK--DGTDIEVVVSKYIFQAILLSAQVMWTELVEKCLQTNQFSKYWKEVDMKIKGLLD-KLNKSSDNV----KKKIEALLVEYLHFNNVIGQL--KNCSTKEEARLLWAKVQKFYQKNDTLDDLNSVFISQSGYLLQYKFEYIGIPERLIYTPLLLIGFATLTDSLHQKYGGCFFGPAGTGKTETVKAFGQNLGRVVVVFNCDDSFDYQVLSRLLVGITQIGAWGCFDEFNRLDEKVLSAVSANIQQIQNGLQVGKSHITLLEEETPLSPHTAVFITLNP---GYNGRSELPENLKKSFREFSMKSPQSGTIAEMILQIMGFEDSKSLASKIVHFLELLSSKCSSMNHYHFGLRTLKGVLRNCSPLISEFGEGEKT------------------VVESLKRVILPSLGDTDELVFKDELSKIFDSAGTP-LNSKAIVQCLKDAGQRSGFSMSEEFLKKCMQFYYMQKTQQALILVGKAGCGKTATWKTVIDAMAIFDGHANVVYVIDTKVLTKESLYGSMLKATLEWRDGLFTSILRRVNDDITGTFKNSRIWVVFDSDLDPEYVEAMNSVLDDNKILTLPNGERLPIPPNFRILFETDNLDHTTPATITRCGLLWFSTDVCSISSKIDHLLNKSYEALDNKLSMFELDKLKDLISDSFDMASLTNIFTCSNDLVHIL--GVRTFNKLETAVQLAVHLISSYRQWFQNLDDKSLKDVITLLIKRSLLYALAGDSTGESQRAFIQTINTYFGHDSQELSDYSTIVIANDKLSFSSFCSEIPSVSLEAHEVMRPDIVIPTIDTIKHEKIFYDLLNS--KRGIILCGPPGSGKTMIMNNALRNSSLYDVVGINFSKDTTTEHILSALHRHTNYVTTSKGLTLLPKSDIKNLVLFCDEINLPKLDKYGSQNVVLFLRQLMEKQGFWKTPENKWVTIERIHIVGACNPPTDPGRIPMSERFTRHAAILYLGYPSGKSLSQIYEIYYKAIFK-LVPEFRSYTEP-----FARASVHLYNECKARYSTGLQSHYLFSPRELTRLVRGVYT-AINTGPRQTLRSLIRLWAYEAWRIFADRLVGVKEKNSFEQLLYETVDK--YLPNQD-LGNI---------SSTSLLFSGLLSLDFKEVNKTDLVNFIEERFKTFCDEELEVPMVIHESMVDHILRIDRALKQVQGHMMLIGASRTGKTILTRFVAWLNGLKIVQPKIHRHSNLSDFDMILKKAISDCSLKESRTCLIIDESNILETAFLERMNTLLANADIPDLFQGEEYDKLLNNLRNKTRSLGLLLDTEQELYDWFVGEIAKNLHVVFTICDPTN-NKSSAMISSPALFNRCIINWMGDWDTKTMSQVANNMVDVIPMEFTDFIVPEVNKELVFTEPIQTIRDAVVNILIHFDRNFYQKMKVGVNPRSPGYFIDGLRALVKLVTAKYQDLQENQRFVNVGLEKLNESVLKVNELNKTLSKKSTELTEKEKEARSTLDKML-MEQNESERKQEATEEIKKILKVQEEDI--RKRKEVVMKSIQDIEPTILEAQRGVKNIKKQQLTEIRSMVNPPSGVKIVMEAVCAILGYQFSNWRDIQQFIRKDDFIHNIVHYDT---TLHMKPQIRKYMEEEFLSDPNFTYETIN--RASKACGPLYQWVNAQINFSKVLENVDPLRQEMKRIEFESLKTKANLLAAEEMTQDLEASIEVSKRKYSLLIRDVEAIKTEMSNVQ---ANLDRSISLVKSLTF----EKERWLNTTKQFSKTSQELIGNCIISSIYETYFGHLNERERAD--MLVILKRLLGKFAVKYDVNYRFIDYLVTLDEKMKWLECGLDKNDYFLENMSIVMNSQDAVPFLLDPSSHMITVISNYYGNKTV-LLSFLEEGFVKRLENAIRFGSVVIIQDGEFFDPIISRLISREFNHAGNRVTVEIGDHEVDVSGDFKLFIHSCDPSGDIPIFLRSRVRLVHFVTNKESIETRIFDITLTEENAEMQRKREDLIKLNTEYKLKLKNLEKRLLEELNNSQGNMLENDELMVTLNNLKKEAMNIEKKLSESEEFFPQFDNLVEEYSIIGKHSVKIFSMLEKFGQFHWFYGISIGQFLSCFKRVFIKKSRETRAARTRVDEILWLLYQEVYCQFSTALDKKFKMIMAMTMFCLYKFDI-ESEQYKEAVLTMIGVLSESSDGVPK 3735 HSP 2 Score: 82.0333 bits (201), Expect = 2.162e-15 Identity = 52/195 (26.67%), Postives = 91/195 (46.67%), Query Frame = 3
Query: 11379 LHKCSQNGDWLCLKNLHLVTSWLPV-LEKELNSLKP---HKDFRLWVTAEPHIGFSTI---LLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGT-RANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIK-KSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDS 11936
+ K G W+ L+N+ + SW+ L K + K H+ F++++T H+ + LLQ + + YE PG+ + + D W F + SG F L+WFHA+I R +P G++K Y F+ D + + L+ ++ S NI W + ++GG++D D+ V++ F S
Sbjct: 3829 ISKSKIEGGWILLQNIQMSLSWVKTYLHKHVEETKAAEEHEKFKMFMTC--HLTGDKLPAPLLQRTDRFVYEDIPGILDTV---KDLWGSQFFTGKISGVWSVYCTFLLSWFHALITARTRLVPHGFSKKYYFNDCDFQFASVYLENVLATNSTNNIPWAQVRDHIATIVYGGKIDEEKDLEVVAKLCAHVFCGS 4018
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Nematostella
Match: EDO38992 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBE7]) HSP 1 Score: 4618.53 bits (11978), Expect = 0.000e+0 Identity = 2341/4381 (53.44%), Postives = 3137/4381 (71.60%), Query Frame = 3
Query: 111 DQRKDTIFLITKSHF--PNQNSKFV---NEECLDKFFDNLDNNVLVVKF---IDNKFI-FSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSK--KSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQ------VNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRS-------RQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSV--GSQ--SKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSAD-STFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDL-PVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKS------------------LGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLK----------------------IPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISD-----KSDRNI--TVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNR-NIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSV-VNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNII--KASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
D RKD + ++F P +S F + L+ F D+ ++ +L +F NK + + + +D +VF K P +ITPDN++ + V+++ ++PI++LY+ +Q I+ P+LL D DPK+Q L+SELE GLGS++RK + ++ DE+ + GI + DE +W DS S S +D ++ E F Q+ V+++ + L+++ +E+ L+++W+ E P YP+ RM L+ +I L R +Q +L+ L W+ + VKE++ + + VC W+ C+ L +YWK++ H W + + +S RL E+ +LRTVHEQ+ ++L ERQ+ + EAF F + PL NPYTEP+W+ AV ++ R + PAE I +L+ F++ ++ QLLR FQRY +L+ RP IS L ERETLL QL ++ K +R+DF+ ++ + G P KN + ++ IVW +QL++K+ E+L ++L DL GF F +E + EE+S++ +QFE W+ EM ++D + + L GRLMEL +DG L V+Y DRLV L+REVR L+ LG+ + + + KFY ++LKQVA FYNTI+ QMIP QQ+MMLD+A+ FE+LVK+ GS S + V W+ P EL +I+KLQ A+ + S+NR LRK H+ I +K+VNLM IDLLRQQ +WK+ L ++R+I+ + EN WK H D QLYKALE+QY +GLE LNENLPEI+V+L +RQ RLQF P EEI++KYF+EM+KFI++PN F+G+ + + QL+ ++ NA GF Y KAE LF+RL A FK+W++LGS+DL+ VD+H D+ D+E+NF+A+K +G++AEKLP +K+DCITV+ P+K ++D IQ +FDAL++SLR++I + ++D +LT+ ++ LS RPQ ++EI EA L H E + +I+ +K+E N LLR VAGGG++ + QLQ +WDKFELM+ES ++M++EQ+EVMK+N+ SR + FQQ++ KF RW LKP +DI QAC+ AV +K++K E EL L +C HF + F + +++ +DI + MW FEE+ TGL+ LAKEDW+SFRSR +LF++FLT W E LR E T MT+RLQK+++ YK+++P+LK++RGE LSQDHWLE+FRLL MP+G TLE LT +L++A +I+ HA+ +KELN +AQGEV+IREA+RELELWGAGAVF L Y DS +S+IK+W+++++QVGDNQCLLQSLKDSPYY+ F+DKA++WE +LADLDEYL NLNQIQRKWVYLEPIFG+ ALP+E+ RF+RVD+DFRSIM DV+++NRVLSL G++N L T++DQLQRCQK+LNE+LEEKRSLFPRFYFIGDDDLLEILGQ+TNP VI+SHLKKLF GI+ V F++ + II +KS++GEVV L+ V IT EVE WLG+L EMK TL + L+ L R S G++ K+PSQIL L+E + FT RCE + ++ E+ +L YT+A + S + V +LKLK+LILDT+H+I+++ L+ +S+ EW W KQLRFY + C+I+M DAEF+YTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALG LFGRQVLVFNCDEGIDVKSMGRIFIGLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQ +K+K+ LL R++++D NS IFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDN+LIAE I+ S+GFK AK LGRKLVAIFNLS+ELL+ QQHYDWGLRALKT+LKG NLL+ HK + E V S E +++VQALRVNTLSKLT+AD F++L++DVFP +D+K +EY LA A+ KE N+V ++ Q KK LE+YEQLRQRMGVV++GPSGSGKSTIW+LLRLAL KIGQTVK Y MNPKA+PRTQLLG ID+DTREWSDGVLT +ARQVV+EP +IQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FE+HDLSCASPATISRMGMIFLS E TDVK+LV SWL + E ++ LL T+L+D+FYK+L+W+ K+ + + T+ VG V NGLS++ ++ K F LI+GLG NL+ ++ FA V+ T E P+ + L+ +++ + RL ++ E + LS+D L+S P+I T+D++R LD F WL++D ++PF+L GPEGCGK ++L HCF++L+S QV +HCSAQ++P HVLQKL Q C++I++NTGRVYRPK+ ERL+LYLKD+NLPK DKWGTSQLI+FLQQV+TYKGFYD NLE+VGL+GVQ+V SM++ + MGR S++TRFTSIVR+CSI YP QL IY+AYL+PVL + + HP+W ++ LA +M+ VY Q+++KFTVDDYSHYLFTP DLT WVLSLLRYDL P +SD++A LLE+ +YE+ R+F+DRLV R D IL + + S+WSV D L +FVTWG+ A P +GK+ LGKL + K I +GL Y+RE R+LDI++FKEV DN+A++DR LT PGGS+LLAG+SGVGRRT LV+HMHNI+L++PK+ R Y LKQFKNDLK+ +Q AG++GE + +LEDHQ ++ LELINSLL++GE+PGLY+ EELEP+L L+D A++ G RG++ +YFA R++ LHI+LIMD S+ +F++NC+SNPAFFK C+VQW+EQWS++SM++ IP ML+ +EG +T + AK K + D L F+ +H+ C + + R Y+ F++ Y IY +KK + RQ H+Q GI K+++AK +V LK KA EQS+ L EKQ EAD AL++IT+ MQ A+E K EME L K GEE+V L KRK AI+ EL+ IEP V++A+DAV +IK LSEIR+LR PP+VIRDILE VL +MG DTSWVSM++FL KRG+++EI +FDAR+IT + R VEELLT+ +SFDPK AKRAS+AAAPLAAWV+ANVK+S LEKI PLENEQ QL+RNL+ ++++++ L + + VD VA R FE T +A +L+ EL A ETI+AAE LV KL+ EF RW Q V Y+ S+PED R++ M+ W + LE F++R+FL+TE EQL WK EGL SD+LSMENALVI++ + PFL+DPSS AT WLK + KD++LE++NQQDSNFST LEL+VRFGKTL+IQE+DG++PVLYP+LRGDLISQGPR VVQ+G+K+IDYN DFKLF+ATRNP P LPPDA AI+S VNFTTT+AGL GQLL +T+QH KP+LE +KT LL++EE+LK++L++ME+SLL+ LA+A GNIL NKDLL SLNKTK SS+TI++SL+++ ++Q +LD+ERDA+LPLA+ GS++FFVISDL+K+NNMYRFSL+SFLRLFQR+L T++ S+ + +R +L + L+ LV+EYVCRS+FK+DRLMFALH+ H P+LF+ +EWE F G ++D +S +N+ ++P W+++DR +L + L+ L+++ D W FA+SS+CE+E P + K+ LFQ++L++QA RPDRLQSA++ F L +K LSP ++NL ++ + ET+ EPILI+ISPGADPSQ+LQEL+ +++G +RY+QVAMGQGQADI + LH C++NG+WLCLKNLHLVTSWLP LEKELNSL+PH+ FRLW+TAE H F TILLQSSLK+TYEAPPG+K N+LR+YD+WS +F+ + + TRA ALF L+WFHAI+QERRN+IPQGWTKFYEFS DLRAG EI+D++ S +++W+F+HGLF NAI+GGR+DN FDM+VL SY+ +YF +V GS F +DYL IIN L D + PSFF LP NI+RSSQRIISSQVI QL++L R V KFDK+ WS EL+P+LN WK LNQG +I K S P + +DSPV +F+ LERY+++ LV+ VH+SL +LSKV++G++LL+ EVQ L+ LL + P W WEGP +P ++R L+ K A+ W E SE LL LDL +K +MD LK W G AKY VK+G L IEGC FDG +TE DS S+ +P ++ WV K+ P+ Y E + IS+PIYY+ RD IVT ++PC G Q+ W+Q G ALFLKS
Sbjct: 5 DSRKDFVLTTAANYFGVPISDSAFAEVSDSRELNAFLDDGNSPILAARFDTHQGNKTVELFDHVEPSDSAEKVIVFFKLQPEVITPDNLHQNVFVSSMLDSPINTLYHSVQKIFAPLLLKDEKWSRNFDPKLQSLLSELEAGLGSVVRKQNTSLARAVQPGDESSLGGILTPQDEFQYWADS-SVSGYDLSE---RERAGFFQECFQKGNVSQDFSNLDGLDLDDTLELVESTQDSLDEVWKQEDHKP-YPEHRMCHLLSVIGGALARYVQRKLSALDIWQGPFQNVKEAMRKGVSVCERWVSTCETLTAQYWKRFPAHPWKGEKFVP-ENLSQLAARLEEVLTLRTVHEQLVRLLSSSERQQLRTAEAFHPFSGLNPLHQNPYTEPLWRAAVGQYERGMAPAEQKIAGKLRQQFRDLSAQS--HQLLREFQRYKELVKRPSISKELAPERETLLGQLTVYVKSIRDDFLAKTQSSYSGDKDGGPPKGKNMPEIVNNIVWVRQLDSKVKEVLVTAESLLGDLAGFRGFRREASDLAEELSSYCTDQFESWSSEMLSAIEDPKHP-LGLQTSGRLMELGHQDGKLRVHYGDRLVTLMREVRHLAALGFVVPAKIQHTSQTASKFYRHGMVLKQVAHFYNTIDQQMIPSQQSMMLDSALAFERLVKNPKQGSNDASGHRTQVTWDKPSELEAYINKLQAAAERLTSENRRLRKCHYNISDKVVNLMSIDLLRQQPRWKEALVDLREIMTSLVQHGFKAENMRTWKMHWDRQLYKALEHQYQLGLEGLNENLPEIKVELTFRQQRLQFRPPLEEIRAKYFREMRKFISIPNHFRGVGEDNSFYQLM----VDHNAPGFSTVYSKAEDLFRRLVAVQEMFKDWVVLGSIDLDALVDKHLHDVADWERNFRALKARGRDAEKLPLSVKVDCITVSTVPVKSTIDDHIQQLFDALMSSLRRSITQEVQTIDTFLTSGMEALSTRPQTVEEIGEANLKHTELTSQKPQIQPLFEKAESKNKLLRNVAGGGVEQIGQLQARWDKFELMLESHELMVKEQVEVMKSNVESRVQAFQQELDKFAARWHQLKP-KDIDVDTDRQACIAAVTSVKERKAEFVELEETMKKLIFECSHFGVTEPHFPVADDLRQDISTTEDMWRLFEEFNTGLEELAKEDWISFRSRTFLFDDFLTGWGENLRTKEPTVMTVRLQKDVEKYKNVVPLLKYVRGEALSQDHWLELFRLLKMPKGTTLEKLTFGSVLESADQIVTHADVLKELNSRAQGEVSIREALRELELWGAGAVFSLTSYSDSHEKELSIIKDWKELVNQVGDNQCLLQSLKDSPYYKGFEDKASIWEGRLADLDEYLHNLNQIQRKWVYLEPIFGRGALPREQGRFKRVDDDFRSIMMDVSKDNRVLSLVGRPGIRNTLVTLLDQLQRCQKSLNEFLEEKRSLFPRFYFIGDDDLLEILGQATNPTVIQSHLKKLFAGIHHVGFDEGNKTIIAIKSIEGEVVPLKRPVNITPEVEAWLGHLAVEMKDTLRELLTQCLDISRKGGGS--GVDPSKFPSQILNLAEQVQFTERCEVAIKSGSLQEFLIEMESQLESYTSADVQGSGEPGDSHVLELKLKALILDTIHSIEVVQNLIKAGVKSLDEWMWQKQLRFYMHKGE--CMIRMCDAEFHYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQAALKSKMASTELLGRQIDIDFNSGIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNELIAETIMFSEGFKEAKSLGRKLVAIFNLSKELLSKQQHYDWGLRALKTILKGCGNLLQSHKQ--------SGEKVNPS-IEARVVVQALRVNTLSKLTFADSRRFDALVQDVFPGVDVKGVEYMELAEALRAAAKECNLVVMETQVKKALELYEQLRQRMGVVVIGPSGSGKSTIWRLLRLALGKIGQTVKQYTMNPKAMPRTQLLGQIDMDTREWSDGVLTNAARQVVREPIDIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFESHDLSCASPATISRMGMIFLSDEDTDVKALVKSWLANRPEDERRLLETWLEDYFYKALEWVLKQGDLVVETTLVGMVMNGLSHMFEVRAKQQFVCSLIRGLGANLSVTTQTAFAKEVFHWTHEMPPDPKRP--LDTFYDSDRGRLASFELEVPDSLSVDDLISTTNG-QPVIKTSDVKRGLDMFSPWLHTDYREPFLLVGPEGCGKEMLLRHCFEQLRSTQVAIVHCSAQSSPAHVLQKLQQMCMVISTNTGRVYRPKDCERLVLYLKDLNLPKPDKWGTSQLIAFLQQVLTYKGFYDDNLEWVGLEGVQVVASMSAGTGMGRHSITTRFTSIVRVCSIGYPDHSQLQAIYSAYLQPVLHKTLRSHPVWGSVRNIQTLAGSMVFVYDQIRAKFTVDDYSHYLFTPRDLTNWVLSLLRYDLDPGSSDSSANLLLEVWAYEARRLFRDRLVGKQGLDRFDSILASQLRSDWSVSF-DRLETTYFVTWGAHTAMPANPAPGEEGKADGGAPVLSSGALPPYGRKLGKLETSDFKQVISKGLKTYARENRELDILMFKEVLDNIARVDRTLTVPGGSLLLAGRSGVGRRTAVTLVTHMHNIELVTPKVSRAYGLKQFKNDLKTVMQKAGIDGEQMAFVLEDHQLVDAAILELINSLLSAGEIPGLYSPEELEPLLSPLRDQASQEGFRGTMFSYFASRVRTNLHIVLIMDSSSPSFIVNCESNPAFFKTCAVQWMEQWSKESMIQSKCFVAQFVSASLYGASHHRWPIPRMLMP----DEG--VTADQAKGKK--SSGDELVKSFIAIHEGCDPKDAAPRRYMTFLQNYKAIYTEKKEGLVKRQTHLQAGISKLTDAKNLVDNLKQKAGEQSRKLAEKQEEADTALQEITTSMQRASESKSEMETLKQKQGEESVKLEKRKKAIEIELSEIEPLVQEAKDAVGNIKPESLSEIRSLRMPPEVIRDILEAVLRLMGIFDTSWVSMKSFLAKRGVKDEICSFDARKITPDIRASVEELLTKNANSFDPKLAKRASVAAAPLAAWVRANVKFSVVLEKIEPLENEQAQLQRNLDKSQQRLEKLGRALDKVDHEVAEMRNRFELRTKEATQLKMELDKAQETIAAAETLVSKLDGEFNRWTGQ------------------TGFVTYLSSAPEDVRRDTMKRWCDSMALEGFELRRFLSTESEQLVWKSEGLPSDDLSMENALVIMKSAVRPFLVDPSSRATEWLKTNLKDQRLEVINQQDSNFSTGLELAVRFGKTLLIQEMDGIDPVLYPILRGDLISQGPRFVVQIGEKVIDYNEDFKLFMATRNPNPDLPPDAFAIISEVNFTTTRAGLTGQLLGITIQHEKPQLEVKKTELLRKEEELKVQLAEMEDSLLETLASAEGNILENKDLLDSLNKTKASSLTIAESLQDAHRVQTTLDQERDAYLPLAQSGSTMFFVISDLAKLNNMYRFSLSSFLRLFQRSLETNQDSSSTELRIKALKSSLQLLVHEYVCRSLFKADRLMFALHLVHGTHPELFQEKEWEFFCGLVVTDMFKRQESMKNLRESLPSWMESDRAGPAGSLKNTFTTLYKTLDLESSDTWGSFARSSQCEQEFPSQITKKICLFQQVLVVQAFRPDRLQSAMNMFASKALGMKELSPPTLNLKRLVK-ETVPGEPILIVISPGADPSQELQELAGEIVGIDRYHQVAMGQGQADIAMQQLHNCARNGEWLCLKNLHLVTSWLPTLEKELNSLEPHEKFRLWLTAESHPKFPTILLQSSLKVTYEAPPGIKKNMLRTYDSWSPEFVQRGNNSTRAQALFVLSWFHAIMQERRNYIPQGWTKFYEFSFGDLRAGAEIIDRLCSDSGSGSVRWQFVHGLFANAIYGGRIDNTFDMKVLESYLLQYFEQAVFAQGSCLFV-----------QDYLEIINSLPDVDKPSFFGLPANIERSSQRIISSQVISQLKVLMRSDVVAHKFDKEKWSTELSPILNLWKKLNQGSQLIQMKVSPP---SETGSDSPVTSFVLLERYSAVTLVQTVHASLAALSKVIRGTQLLSAEVQTLAASLLRQEVPQEWTSIWEGPMDPVHWLRALVSKTLALGSWVERSEARTLLKDTLDLA-------------------LKTAMDNLKPAVAWKGGVPGAKYPVKLGGLQIEGCTFDGNALTENQNDSPSVSAVPTATMAWVPKDSPDPYPESECISVPIYYNSDRDSIVTCFNMPC-GGNQNYWLQCGAALFLKS 4293
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Nematostella
Match: EDO34077 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQG6]) HSP 1 Score: 1220.68 bits (3157), Expect = 0.000e+0 Identity = 878/3186 (27.56%), Postives = 1586/3186 (49.78%), Query Frame = 3
Query: 2772 IKIDCITVNCAPIKMSVDTLI---QNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRS-------QIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFE-----------------KLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIF----GKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNK-----DIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENN-------IITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQ-------TVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQ-DEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAH-----------------FSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKL--KSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTM----IEVYSQLKSK-FTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKD-TIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRG---SLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQ-NSAKPKTQLTGS--DNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATER----KGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRC-KDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKE-KMQLWMEKT---GLE---KFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF--TGTFISDKSDRNITVPKWIDA---DRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECER-EIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLK---PHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANA-LFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRD 12002
+ ID + ++C+P+K ++ + QN F LL R+ + ++ +L + K LS P+ +DE+ ++ + D I + Q EK + G +D +S +W F+ + +M+++ E KT ++ ++F++ + D +Q P S+ +A++++ ++ L +T+L + F++E L+ + KD++ + +W+ +E++ E W +++ ++ E +T E K +N EI ++ I+ +K +P+++ ++ + HW ++ + P T + TL I++ + + E I E++ A E++I +AI + + Y D + + K+ ++ Q+ DNQ L ++K S Y + F+ + WE L+ + E ++ + +QR+W+YLE IF + LP+E + F V+ +++ IM +N++ L G+ L+ M +L+ QK+L+ YLE KR +FPRFYF+ +DDLLEILGQS NP+ ++ HLKK F I + + D + M S +GE VE + VL+ VE WL ++ M+ TL + L + L+ S S ++P Q+ S + +T+ C + L+ + + +LKK+ V LN ++ + S + LK+ +L+ VH D+I++L+ C VT +EWL QLR Y CV++ + +F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC EG+D KSMGR++ GL + G+WGCFDEFNR+ VLS V+ QI I + R +N+ + IFIT+NP GY GR +LPDNLK +FRP++M PD+ +IAE+IL ++GF N K L +K+ ++ L+ + L+ Q HYD+GLRAL +VL+ A G N SD E L+ +++ ++KLT D F ++ D+FP I+ I+Y L +AI +K+ K++++YE R ++VG +GSGKS W++L+ A+ ++ + V+ + +NPKA+ +L G D++T EW+DGVL+ RQ + + + WI+ D +D WIES+NSV+DDN++LT+ +GERI V+ +FE DL+ ASPAT+SR GM++ + V SWL ++ D+ L + F K L++ + + TS + +V + A+ + + F CLI + +++E+SR+ ++ EL + K V Y+ + KQ ++ + + + KI+ P + T F ++ ++P +L+GP G GK+ + QKL K+ + ++ SAQT+ V + + + T VY P +++I ++ D N+P D +G+ + ++ I Y +YD + V + + GR +S R S L ++++P + Q+ I+ + L+ VK L + M IE+Y+ + +K HYLF D+++ LLR + + TA+S L + +E R+F DRL+ + R+ +L + + S + + + + +G+ + K++ + + ++D ++ G++ ++++LF++ ++V ++ RV+ +P G++LL G G GR++ + L S++ K+ ++ + Y ++F++DLK AGV+ + V L D Q LE +LE +N++L+SGEVP LY +E E + +L D+A + + S+ ++F +R++ LHI+L M F + PAF ++ W +W D++L++ + I E G + T+ N A+ + S D L+L + T +Y+ + Y + +KK E+ + ++ G+ KI + + V + + + + + E Q + ++ L I + A E+ + EK+ ++ + V+ + +D+ + P +++A A+ + D++EI++ PP ++ ++E V +I+ + +W + LG +++ +D +T RI ++++ T C + F P+ R S+AA L WV+A Y + P + +Q LE + + + + + +V + ++ +++ +A +L + + + A LV L E +RW + L + L L+AAA + Y + R E ++ W+ + G+ F FL EW +GL SD S EN +++ +G P +IDP A W+KN L+I++ Q S++ LE +V+FG +++Q V + L+P L P+L ++ G R +++LGDK ++Y+PDF+ ++ T+ P P+ + VNF + GL+ QLL + ++ +P+LEE+K L+ K +L ++E+ +L+ L A G++L+++ L+ +LN +K +S +++ L S + ++ +D R+ + P A+ S LFFV++D+ +I+ MY+FSL +++ LF ++ S+ S + R +L VY+Y CR +F+ +L+F+ M C + E+ F G + + + +W+ D + L + + S D W+Q+ SSE E +P +N + Q++L++++LRPDR+ + F + L K + P +++ + + + + P++ ++SPG DP+ L +L+ S R++ +++GQGQA I ++ + ++G+W+ L N HL SW+P L+K + L+ PH DFRLW+++ PH F +LQ +K+T E P G+K N+ R Y +E S+ + LF L +FH+++ ERR F+ GW Y F+ +D +L I W + L +GG V + FD R+L SYI FND + +Y LP+ +D
Sbjct: 828 LNIDFVLLDCSPLKFALLSHCNEWQNKFTTLL---REMASQKLTELNNFLKGNAKKLSAPPETLDELGDSLSLLEQLQNDLPNIEAKFAPLHQQFAILEKYEVAIPEEVQGMLDALSG---EWLLFQQCLIDSDVMLKKSKEKFKTGLIHSSEEFKKTVNGLFDDFQSKGP------FSSSIGVKEALEQVTQYHEQVVNLKSQETSLRRGLNIFKIEQALSKDLQNLEKDLEHLEQVWTVTKEWE--------ELWDTWKVGKFV--ELVTTDMETQAQLLFKRLNKIIREVKDKNWEICD---SIKSRIEQFKRTMPLIQDLKNSAMRDRHWSQIKTEVQKPFDHTGDDFTLEKIIELGLD--QFGEQICEISGAASKELSIEQAISGIASIWDQVSLDIGPYKDRGHFRL---KQTDEVFQQLEDNQVTLSTMKASRYVKAFEAEVDKWERTLSLILEVVEMILTVQRQWMYLENIFLGEDIRKQLPRESAEFDDVNANWKIIMQRLNKDPNALRGTHYPGLLETLNDMNTKLEEIQKSLDMYLETKRQIFPRFYFLSNDDLLEILGQSKNPEAVQPHLKKCFDNIKTLKMARVGLTFDKTEAVGMYSAEGEYVEFGHSVLLEGPVEAWLCDVERSMRWTLKELLKHCRLGLKKS-LSKRDKWVKEWPGQLTITSSQMQWTSDCNKALSSSKERGDKKALKSLKKKQVSMLNKFS----EMIRGSLTKMQRLKIVALVTIEVHGRDVIEKLIKAGCNDVTAFEWLSQLRLYWDKDIDDCVVRQTNTQFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGNYVIVVNCSEGLDFKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSALSAGATRFVFEGREINLVWSCGIFITMNP---GYAGRTELPDNLKSMFRPISMCVPDSGMIAEIILFAEGFNNTKVLAKKVHTLYTLAVQQLSKQDHYDFGLRALTSVLRYA--------------GRKKRANPDMSDEEILLL--SMKDMNVAKLTTQDAPLFNGIVSDLFPGIEAPVIDYGKLRNAIVAELKDGGYQPTPNTILKIIQLYETKNSRHSTIVVGQTGSGKSVTWRVLQSAMTRLKRDGEPGFNVVREFPINPKAVSLGELYGEFDLNTNEWTDGVLSSVMRQTCSDEKPEEKWILFDAPVDTLWIESMNSVMDDNKVLTLINGERISMPDMVSLLFEVEDLAVASPATVSRCGMVYTDFRDLGWQPYVDSWLDRRVDKQSVEHLQRLFEKFVPKVLEFRKHHCKEPVPTSELNSVVSLCVLFDALATEENGVRMSNGESYARMLELWFLFCLIWSVCASVDEDSRKKMDNFLRELEGQFPA---KDTVYEYHVDIKQKTWASWEDKLRSGWRYNPSVPFYKIMIPTVDTVRYD-----FLVYNLIQAKRPVLLTGPVGTGKTSVAQKVLQKLDPKTYGLLVINMSAQTSSNDVQEIIESK---VEKRTKGVYVPIGGKQMITFMDDFNMPAKDTFGSQPPLELIRLWIDYGFWYDRMKQTVKYVKDMHLLASMGPPGGGRMVISKRLQSRFNLINMTFPQESQIKRIFGTMINQKLQDF---------EEDVKPLGDIMTQATIEIYNTIVAKMLPTPTRIHYLFNLRDISKIFQGLLRANKDLHDTKTAISRLWV--HECFRVFSDRLIDNTDRESFVTLLSDKLGSMFDLTFHNLCPNKQSPIFGNFMKDDTMYEDLVDFKAIKRYMEDQMEDYNMEPGVIA-------INLVLFRDAIEHVTRIVRVIGQPRGNMLLVGIGGSGRQSLTRLASYIIEYKVFQIEVTKHYRRQEFRDDLKRLYYQAGVDNKPTVFLFNDTQALEEGFLEDVNNILSSGEVPNLYKPDEFEEVRTALSDIAAKEDVQDTPESMFHFFIERVRSNLHIVLCMSPVGDPFRNRIRMYPAFVNCTTIDWFSEWPGDALLEVAERYLENI--ELGDEETKANVAQIFVTVHRSVVDMSARMLLELKRH---NYVTPTNYLELVSGYQSLLAEKKKELGDAASKLRNGLDKIDDTRAKVEVMSVELEDATLKVAEFQKQCEEYLVVIVQQKREADEQQKMVQARSEKIAIEEDKCRVMAENAQHDLDEAI----PALQEAMKALESLNKKDMTEIKSYGRPPALVEKVMEAV-MILRQSEPTWAEAKRQLGDGNFIKQLVNYDKDNMT--DRI-LKKIGTYCAQPDFQPEIIGRVSLAAKSLCMWVRAMEVYGRIYRVVEPKKQRLHQATAQLEEKQAILAEAKAKLKEVTDRMEELKRQYDEKSAQKEELRAKAELLEIKLDRAGKLVSGLAGERDRWEASVTILEENIGYLVGDCLIAAAFMSYAGPFLSNYRDELVLKTWLAQVRQLGVACNPNFSFSGFLAKPTTVREWNIQGLPSDAFSTENGVMVTRGNRWPLMIDPQGQALKWIKNMEGKSGLKIIDLQQSDYLRTLENAVQFGSPVLLQNVQEELDPSLAPILNKSVVKVGGRYLIKLGDKEVEYSPDFRFYITTKLSNPHYTPEISTKTTIVNFAVKEQGLEAQLLGIVVRRERPELEEQKDALVINIAAGKKKLEELEDEILRLLQTAQGSLLDDEQLVNTLNSSKTTSQEVAEQLTVSEQTEIKIDAAREGYRPCAQRASILFFVLNDMGRIDPMYQFSLDAYIDLFNNSIEKSQRSPNLDNRIQNLNEYHTYAVYKYTCRGLFERHKLLFSFQM--CSKILEAAGKLNMDEYNFFLRGGVVLDREGQMDNPCTQWLTDTSWDNVTELDKLPNFHGIVTSFEQYPRD--WNQWYTSSEPENTPLPGEWENACNELQRMLVVRSLRPDRVSFTATSFIVNNLGSKFVEPPVLDMSSVVDDSS-TRTPLIFVLSPGVDPTSALLQLAENCGMSNRFHALSLGQGQAPIATRMIKEGVKDGNWVFLANCHLSLSWMPQLDKLVEQLQVEDPHPDFRLWLSSSPHPEFPISILQVGIKMTTEPPKGLKANMKRLYQLITEQQFSRCHKQDKYKKLLFGLCFFHSVLLERRKFLMLGWNIVYGFNDSDFEVSENLL-SIYLDEYEETPWDALKYLVAGVNYGGHVTDDFDRRLLHSYINEMFNDQAIQTP--YYKLSSLPTYYVPKD 3909
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Nematostella
Match: EDO35852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK91]) HSP 1 Score: 1175.61 bits (3040), Expect = 0.000e+0 Identity = 913/3252 (28.08%), Postives = 1575/3252 (48.43%), Query Frame = 3
Query: 3609 LQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIREL-ELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQH---IITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELL------NENNIITLKKELVKKLN-IYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQ-SWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLK-KQDEHDQHLLSTYLDDFFYKSLDWI---------AKRNEFTISTSNVGTVYNGLSNLKAI-------------KNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQL--------MSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTL----HCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQI-VCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIY----TAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQL-------KSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNA-----KRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEK-------FDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDG-LEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMS-HCCRPD-LFKPQEWELF-TGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNI---KDDDLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKV-IGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSL-KPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRN----IQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNG--SGNFYGKIQLPSAASK---------RD-YLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLP-----DSLKRS---STDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPF-DYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSN---VSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDK-----IVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
L++++ +K+ IP+ ++ E L + HW ++ + M L E TL+++ A E+ ++ I ++ A E+ I + I E+ + W A F + +Y+ ++ +I+ + DN LQS+ S + F + WE L+ + E ++ +QRKW+YLE IF + LP+E +F +D+ F+ IM+D +N +VL C + L +++ L++CQK+LN+YL+ KR+ FPRF+FI DD+LL ILG S +P ++ H+ K+F I + F + M S +GE ++ R V VE+W+ ++ EM+ T ++L NQ +Y + + +T E++ ++ + ++ ++++ + + +LS + K ++++ VH DIID + + E+EW QLRFY +I+ EF Y YEY G +LV TPLTD+ YLT+TQ + M LGG P GPAGTGKTE+ K L G +V NC EG+D KS+G+IF GL +CG+WGCFDEFNR++ +VLS VS QI+ +Q+ + + ++ + + +D IFIT+NP GY GR +LP+++K LFRPV PD I E++L S+GF AK L +K+ ++ L+ L+ Q HYD+GLRALK VL A L K + E+V ++++ALR L K + D F LI D+FP +D + Y N A+E + + + L Q K++++YE + R +IVGP+G GK+ + L +A ++G K YVMN KA +L G +D TR+W+DG+L+ R++ K + + +I+ DGD+D W+E++NSV+DDN+LLT+ +GERI+ + +FE DL ASPAT+SR GM+++ + + W + + ++ L + + S+D I K+ + I +N+ V L A+ +A F LI G L E+ R + + L V Q L Y ++ ++ L + L D K L+ T D R ++ +N +P +L G G K+ + + + Q TTL + S++TT ++V L + T Y P +RL++++ D+N+P++D++GT Q I+ L+ ++ G YD E + + I + GR+ + RF S+ + ++++PS++ L IY T +L+P K + V+ + + +E+Y+ + SKF HY+F DL++ V L P D+ A + + E MR+F DRL + R+ G + + + +S ++ D +G P + + + K + L +Y+ + ++++LF + +++ ++ RV+ G LL G G G+++ + L + + + RGY+ F+ DLK + G+E + +V L D + +LELIN++L SG VP LY +E E I+ ++D AN++G R S+ YF ++ + LHI+L M C++ P L +KIP ++ + + Q G+ + S+ L V ++T ++Y++FI Y R+ K + + + ++ G+ K+ A E +AEL K A Q +TEK +K L +I Q A E+K + E+N ++ K ++ LA P +++A+ A+ D+ SD++EIR+ PP ++ + E ++ + G + SW S + + + + + D IT + +C+D N K S A A L +V A + Y +I P + +L+RN ++++++ +EK + +++ + K ++ + + L+ E + + AA+ L+ L +E RW K + +L + L LL AA + Y+ + D R++ ++ E +++ F + LT + E +W EGL D+LS+EN ++ Q P IDP A W+K + L++V D +F LEL++++G ++ ++VD ++PV+ +L ++ + R+ V LGDK +DY+P F+L+L T+ P+ P + VN+T T GL+ QLL++ + + +LEE++ L+QE + K L +E++LL+ELA + GN+L+N +L+ +L TK ++ +S+ L+ K + +D+ RD + P A+ G+ LFFV+S++S +N+MY++SL S+L +F +L S T + R +++ L VY Y C +F+ +L+F+ M+ D K +E + F G +KS R W+ + L PE++ L +++ W +++ E P + LS FQ++L+++ R DR+ A++ F + K+++P ++ I E T P++ I+SPG+DP+ DL +L+ + G + +AMGQGQ + L LL G WL L+N HL+ WL LEK L + KPH DFRLW+T +P F +LQ SLK+ E P G+K NL +Y S ++ + + +F L +FHA++QERR + GW Y+F+ +D R +L+ + KS +N I W + L ++GGRV + FD RV+ +Y+ Y D + + +FY ++ K RD Y+ I +L N+P F L N + + + L L LQ T D SRE + + + + I+ LP D ++++ T + VV +L+R+N L++ + +SLI+L + L G ++ E+ +S L G PN+W + + ++M + KW E ++ L L PD++L AL Q T R +D V ++ ++ A + L++EG +D + C R VL+ + V V + + + P+Y R +V + D+ + W+ GV L L S
Sbjct: 1177 LEEKMKEFKNSIPLFSDLKNEALRERHWKKLMDMTGMKFDLNPETFTLQNMF--AMELHNFSDVIADITASATKELGIEKGIAEVSDTWNAMK-FTVAKYMKGTQERGFVLGTVDEILQILDDNAMNLQSMSASRFVGPFLETVNKWEKSLSHIGEVVEVWMVVQRKWMYLESIFIGGDIRAQLPEEARKFDDIDKTFKKIMADTAKNPKVLEACHAPNRLDQLQFIVNGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILG-SHDPTCVQEHMIKMFDNIASLRFQEGSNKETLATAMISSEGESMDFRQAVPAEGRVEDWMTSVLKEMRRT--NRLITKEAIYNYCNQITRIEWMMQYQGMVALAGNQVWWTWEVEDVFRKVKKGDKMGMKNYARKCHRQIDDLVVKVRSNLSKNDR-----KKFNTVLIIEVHARDIIDSFVRDSIMDSREFEWESQLRFYWDQAPDELMIRQCTGEFGYGYEYMGLNGRLVITPLTDRIYLTITQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDFKSIGKIFSGLAQCGAWGCFDEFNRIDVSVLSVVSTQIKTLQNSLSSGLKRLQFEGTEIALDARMGIFITMNP---GYAGRTELPESVKALFRPVVCIVPDLQQICEIMLFSEGFLYAKVLAKKMTVLYKLASGQLSKQSHYDFGLRALKAVLVMAGEL--------KRGSPELSEDV--------VLMRALRDMNLPKFVFEDVPLFLGLIADLFPGLDCPRVRYPNFNDAVESSLTDNKYILLPHQADKVVQMYETMLTRHTTMIVGPTGGGKTVVINTLAMAQTRLGMHTKLYVMNAKACTVIELYGTLDPVTRDWTDGLLSNIFREINKPTDKNERKYIVFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQKHCALLFEVADLRYASPATVSRCGMVYVDPKNLGYRPYWQKWCNARSNAKEREELDRLFEKYVPASVDLILEGILDGKQGKKLKTIIPLTNLNMVEQLSHMLDALLPPAESSNFLGPDVTEAIFISSLIWSTGAGLLEDGRIVYDQLIKRLAGIPANPAEGTVVGPGELPSAQPTLYEYYFDSKKLLWVPWLDVVPEYVHNPDLKYNEILVPTVDTVRTTWLLQLMVN--IHRPVLLVGETGTSKTATTANYLRGMD--QDTTLLLNINFSSRTTSINVQHNLEAN---VEKRTKDTYGPPMGKRLLVFMDDMNMPQVDEYGTQQPIALLKLLLEKGGMYDRGKELIWKNVRDIGFVAAMGKPGGGRNEVDPRFISLFSVFNVTFPSEESLRRIYSSILTGHLQPFPKNI---------QDLVEHITTSTLELYTNIIRDLPPTPSKF------HYIFNLRDLSR-VYQGLCLTTPDRFDSPA-KFVRVWRNECMRVFCDRLTNEADRETVSGYISSLVDQNFSEHTDIAMRDPCL--FGDYRNTLTEDPRLYE----DVVDYDATKAIFEEILEEYNMDHAPMNLVLFDDALEHLTRIHRVIRMDQGHALLVGVGGSGKQSLTKLAAFSAGCGVFEITLTRGYDENSFREDLKELYNSLGLENKKMVFLFTDAHVAQEGFLELINNMLTSGMVPALYPDDEKEGIIGQVRDEANKAGVPPARESIWQYFVNKCANNLHIVLAMSPVGDILRTRCRNFPG------------------------LNDKIP-DQYRETVVDHVVFVHQTVGTYS-QSFLQKLRR---VNYTTPKNYLDFISTYNRLLEIKDKYVLEQCHRLEGGLGKLLAASEQLAELNEKLAVQKIAVTEKSEACEKLLVEIQRATQQANEKKEMAIGKKKEIAEQNKVIVVEKTEAEEALAAALPALEEAKLALQDLDKSDVTEIRSFAKPPRAVQMVSECIVALRGYKEISWKSAKAMMSEGNFLKSLTEMDVDGITTGQ-------VKKCRDMLKEMNTTVEEMKEVSKAGAGLFKFVIAVMGYCSVAREIKPKREKVARLERNFHLSKRELEKIEKELKALEEELERLGKQYDDAMREKSSLQEEAEIMERRLIAADKLISGLGSEKIRWTKDLQDLKDQRVRLLGDCLLGAAFLSYLGAFTWDFRRDMLRKQWENDVIQREIPLSKPFKVDVLLTNDVEVSKWTSEGLPPDDLSIENGILTTQASRYPLCIDPQQQALNWIKKKEEKNNLKVVTFNDHDFLKQLELAIKYGFPILFKDVDEYIDPVIDNVLDKNIKGEPGREFVVLGDKEVDYDPSFRLYLNTKLSNPKYTPAHFSRCMVVNYTVTMKGLEDQLLSVIVGVERKELEEQRERLIQETSENKRLLKDLEDTLLRELATSQGNMLDNVELVQTLEDTKTKAVEVSEKLKLGAKTAIDIDKLRDGYRPAAKLGAVLFFVLSEMSVVNSMYQYSLNSYLEVFDLSLRKSLPDTILSKRLKNIMDTLTMNVYNYACTGLFERHKLLFSFQMTIKIMEADGKLKQEELDFFLKGNIALEKSSRQKPY-SWMPDQGWEDVIRLCQVTPEVFGSLADDIERNEKGWREWSDLDAPESHPFPGKYEESLSDFQRLLLLRCFRVDRVYLAITHFVTGRMGEKYVTPPVLSFESILEQST-PFSPVIFILSPGSDPASDLMKLAERSGFGGNKLKFLAMGQGQEKLALQLLETAISRGQWLMLQNCHLLVKWLRTLEKVLERISKPHPDFRLWLTTDPTPEFPIGILQRSLKVVTEPPNGLKLNLRSTYHKISNQMLADCPHQSFSPLVFVLGFFHAVVQERRKYGKIGWNIAYDFNESDFRVCMTLLNTYLTKSLQNTDVKIPWASLKYLIGEVMYGGRVIDDFDRRVVKTYMDEYMGDFIFDTFQPFHFYNNEEVDYCIPKNGENKYDPGRDVYVDYIEELPLANTPDVFGLHPNAEIGYYTNAAKDMWLHLVELQ----PQTAGDSGGISRE--------EFITKIASDIQGKLPPLFDVDRVRKNLSEITPTAVVLLQELDRFNV--LIRRMSTSLINLQRALAGEVGMSSELDEVSRSLFNGMIPNIWRKLAPATLKSLGNWMEHFQKRLDQYNKWVNDGE-----PAVIWLSGLHIPDSYLTALVQATCRKHGWPLDRSTLYTTVTKYHNADEVTERAHSGCFVSGLYLEGASWD--LAESCLRRPKPKVLVEELPVLKVIPIESHRLKLQNTFRTPVYTTSQRRNAMGVGLVFEADL-ATTEHTSHWVLQGVCLTLNS 4308
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Nematostella
Match: EDO47920 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKK0]) HSP 1 Score: 1158.28 bits (2995), Expect = 0.000e+0 Identity = 863/3179 (27.15%), Postives = 1532/3179 (48.19%), Query Frame = 3
Query: 3801 IKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCL-LQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG-----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKD-----IQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFT-------ARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDL------KLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQD-EHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKA-------------HFSVCLIKGLGGNLNENS----RETFA-LWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYS-----YECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKS--VQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYD-SNLEFVGLDGVQ-IVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSK-VKLLANTMIEVYSQLKSKFTVDDYS-HYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLAN---YFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENV-ILAK----RKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTM-----DTSWVSMRNFLGK-RGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQR----KEKMQLWMEKTG-----LEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQE-----LANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVA-ISNLA----SAMPELWSVLNIKDD-----DLWHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKV---IGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLK--PHKDFRLWVTAEP------HIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANA-LFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNR-WKILNQGLNIIKASLPDSLKRSSTDSP--VVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQ-WEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGS--NVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
++ + KA E+ + + ++EL++ + F+ E++ + I L+K ++I + DNQ + LQ+L S Y F ++ W+ KL+ D + ++QR W +LE IF +N LP++ RF +D DF+ + ++ + V+ C+ G+ L + ++L C+KAL EYLE KR FPRFYF+ DLL+IL P + HL KLF + + F +D + + M S +GE VE + +VE WL + + M+ T+ + S ++ + + + +P+Q+ I +T R EE EN I K+ V +L+ N ++ DL K+ ++ VH D++ +L+ Q S + WL QLR + C + DA+F Y+YEY GN P+LV TPLTD+CY+TLTQ +H+ + G P GPAGTGKTE+ K LG G V VFNC E +D KS G I+ GL + G+WGCFDEFNR+ VLS +++Q++ IQD I++K + + + +FIT+NP GY GR +LP+NLK LFRP AM PD +LI E++L ++GF A+ L RK + +++L +ELL+ Q HYDWGLRA+K+VL A +L + + + Q ++++ALR + K+ D F LI D+FP +D+ + + +++ + + + K++++ E L R V ++GP+G+GK+ + + L + + +NPKA+ +L G I+ TREW DG+ + R + + WI+ DGDIDP WIESLN+V+DDN++LT+ S ER+ P++ +FE L A+PAT+SR G++FL+ V+SW+ ++ + ++ L D + LD + R + ++ V L+ + A +F + GG + ++ R F+ WV E K P V +YY + + + V ++ +E + E+ + + L+ TA+ R + + + + ++P +L G G GK++++N FQ L V + + TT + Q L + + GR Y P +++LI ++ D+N+P +D +GT Q + ++Q + Y ++D + L + Q I C ++ S + R ++ +IS+P D L IY + L +K H S SK + + + + + ++ S F HY+F DL+ +L T V + +E R+++D+L+ D +F+ I + + + + L++ + + + + K L E L + L Y+ ++++LF++ +V +++R+L P G+ LL G G G+++ + L + + +++ + +GY + K DL + AG++ V LL D Q E +L LIN LLASGE+PGLY +E+E I+ +++ +G + + N +F +R++ L ++L + + PA ++ W +W +++++ + I + + E ++ A+ + + S N S L + ++T + ++ I +Y + KK E+ + ++ G+ K+ + V +LK+K A Q L +K +ADK ++K+ G K EK E+ V ++AK ++ + +++LA EP + A++A++ + +L+E+++ +PP + ++ V++++ D SW + + +GK +++ +D I + V+ L F+P K S+AA + AWV V++ Y + P L AE+K+ ++ + ++D+ +A +FE+ T++ K + E ++ +TI A LV L +E RW + + + L LL A V Y R +K +++ E D LT W E L +D +S ENA ++ P +IDP W+K + L IV + +E +V G+ ++I+ + + ++PVL L+ + I +G + +++GDK ++Y+ DF++ L T+ P P+ A + +NFT T+ GL+ QLLA + +P LEE K + + ++ L++ L+ A GN L + L+ +L TK ++ I + E+ + ++ +++ R+A+ P A S L+F+++DL+KIN MY+FSL +F +FQ+A+ +E + + R +LI C+ V+ Y R +F+ D+++F ++ + L I + D + P ++ V +SNL+ A+ + N+ D W +FA+S E+E PQ KNK +L QK+ +++ALRPDR+ A+S F + L K++ + +E E+ PI I+SPG DP +D++ K+ ++ ++ V++GQGQ + L ++ G W+ L+N+HLV +WLP LEK+L + + D+R++++AEP HI +L++S+KIT E P G+ NL ++ +N+++D + + LFSL +FHA++ ERR F PQGW + Y F+ DL ++L + ++N + W + LF ++GG + + +D R+ +Y++ Y ++ G N LP + + Y I++ SP + L N + S + L +Q G + ++ VL+ ++ L + N+ P+ + R +P VVAF + ER N L + +SL L LKG +T E+++LS L P W ++ + + L+L+ K +E+W D L ++ L F+P +FL A+ Q AR + +D++ V + N + + L +EG +D T DS L P + V ++ + ++ P+Y R KW +GVAL L S
Sbjct: 1400 VRGIVDKATKELGMEKVLKELDVTWSQMEFEHEEHVRTH---IPLLKSSEELIETLEDNQVVQLQNLMTSKYIGHFLEEVTSWQKKLSTADSVITIWFEVQRTWSHLESIFIGSEDIRNQLPEDSKRFDGIDVDFKELTNEGAKIPNVVECCNRPGLFEKLENLQERLSLCEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNQPVEVARHLSKLFDNMARLKFKEDDAGNVTKDAVGMYSKEGEYVEFDSVCDCDGQVEIWLNRVMDRMRATVRKEQSESVVSYEEKPREQWLFD---FPAQVALCGTQIWWTTEVGIAFGRLEEGY-ENAIKDYYKKQVSQLSTLIN----------MLIGDLSKGDRQKIMTICTIDVHARDVVAKLIQQKVDSAQAFLWLSQLRHRWDDQQSHCFANICDAQFKYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKSCGNIYKGLSQTGAWGCFDEFNRISVEVLSVIAVQVKSIQDAIRDKKERFIFQGEDICLVPTVGLFITMNP---GYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFLEARALARKFITLYSLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRSDRQRPEDQ----------------VLMRALRDFNIPKIVTDDVPVFMGLIGDLFPALDVPRKRDPDFEALVKKSVTDLKLQPEDSFILKIVQLEELLAVRHSVFVLGPAGTGKTQVIRSLNKTYMNQKRKPMMFDLNPKAVTADELFGFINPATREWKDGLFSTIMRDLSNIASDSPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERVPLTPSMRLLFEIGHLKTATPATVSRAGILFLNFADVGWNPYVSSWIDTREVQSEKANLQILFDKYVPVCLDLLRVRFKKITPIPDITMVTTLCYLLECLLTPANTPPDCNKELYELYFVFAAVWAFGGAMFQDQLVDYRTEFSKWWVTEFKTIKFPSAG--TVFDYYIDSETKKFVPWTDKVQKFELDPEVPLQAV---------LVHTAETTRVRFFMDLLM--ENRRPVMLVGGAGTGKTVLVNDYFQSLDPDVSMVGNVPFNYYTTSAMLQQVLEKP---LEKKAGRNYGPPGNKKLIYFIDDMNMPMVDTYGTVQPHTLIRQHLDYSHWFDRTKLTLKDIRNTQYIACMNPTAGSFTINPRLQRHFAVF---AISFPGLDALKTIYLSILNGHMK----VHNFASAVSKFTEKVTDAALAMNQKVTSTFLPTAIKFHYVFNLRDLSNIFQGILFATHECIK--TPVDFARLWMHECNRVYRDKLIDD-----KDMEVFDKIQIDMTKKFFEELDEE--AMYAKPNMFSHFSSGIGEPKYLAVPDWEVLSKLLTEALENYNEVNAVMNLVLFEDAMQHVCRINRILESPRGNALLVGVGGSGKQSLARLAAFISALEVFQITLRKGYGIPDMKLDLANLCTKAGLKNIGTVFLLTDAQVPEENFLVLINDLLASGEIPGLYPDDEVENIISGVRNEVKGAGLQDTRENCWMFFIERVRRNLKVVLCFSPVGATLRVRSRKFPAVTNCTAIDWFHEWPQEALVSVSRRFIEDLEQLE-AEYKPPVAEFMSYVHTSVNEESQMY-LANERRYNYTTPKSFLEQINLYRNLLKKKSKELTQKTERLENGLLKLQSTAQQVDDLKAKLASQEVELKQKNEDADKLIQKV-----GVETEKVSKEKAIADDEEKKVQVIAKDVSEKQRSCEEDLAKAEPALLAAQEALNTLNKGNLTELKSFGSPPGAVVNVCSAVMVLLAPANKIPKDRSWKAAKIMMGKVDAFLDQLINYDKENIHESNLKAVQPYLD--NPEFEPDFIKGKSLAAGGICAWVINIVQFYYIFCDVEPKRKALEAANAELAAAEEKLSKIKAKIQELDENLAELTANFERATSEKLKCQQEAESTAKTIELANRLVGGLASENVRWGESVKSFKEQEKTLPGDVLLTTAFVSYHGCFTRRYRDNLLNDKWLVFLASQNPKIPITEGLDPLSLLTDNATIATWNNENLPADRMSTENATILTNCERWPLMIDPQLQGVKWIKTR-EGNDLRIVRLGQKGYLDTIERAVSNGECVLIENMGENVDPVLDALIGRNTIKKG--RAIKMGDKEVEYHADFRMILHTKLANPHYKPEMQAQTTLINFTVTREGLEDQLLADVVSKERPDLEETKASDRIFPLTQQQNAFTIKLKELEDSLLARLSAAGGNFLGDYALVENLEITKRTAAEIEVQVTEAKQTEIKINDAREAYRPAAARASLLYFILNDLNKINPMYQFSLKAFSVVFQKAIERAEPAEEVKARVVNLIDCITYSVFIYTTRGLFEKDKIIFTAQVAF----------QVLLMKKEIIPHELDFLLRFPAVMNVTSPVDFLSNLSWGGIKALSNMEEFRNLDRDIEGSAKRWKKFAESECPEKEKFPQEWKNKTAL-QKLCMMRALRPDRMTYAVSNFVEEKLGHKYVEDAPTPFAMSFE-ESGPATPIFFILSPGVDPLKDVEAHGKKIGFTFDAKNFHNVSLGQGQEIVAEQCLDLAAKEGHWVILQNVHLVKNWLPKLEKKLEAFSEGSNPDYRVYISAEPAGTPDAHI-IPQGILETSIKITNEPPTGMMANLHKALNNFNQDTLEMCARENEFKSILFSLCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVDVLYNYL-EANAKVPWTDLRYLFGEIMYGGHITDDWDRRLCKTYLEEYMKPEMLEGELNLAPGFPLPPNSDFKGYHLYIDETLPPESPYLYGLHPNAEIGFLTTTSDNLFRTLLEMQPRDAGGGEGASQTREEKVKQVLDDIFEKLPEEFNV-----PEMMARVEDRTPYTVVAFQECERMNM--LTNEMKTSLKQLDLGLKGELTITSEMEDLSNALFLDDVPESWTRRAYPSMFGLAAWFVDLLLRIKELEQWT----SDFCLPNVVWLSGFFNPQSFLTAIEQSMARKNEWPLDKMALQVDVTKKNKEDFNSPPREGAYVHGLFMEGARWDTQ--TGMIADSKLKDLTPAMPVMFIRAIPVDKQDTKNVYECPVYKTRQRGPTYVWNFFLKTRENPSKWTLAGVALLLSS 4471
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Nematostella
Match: EDO31800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWW2]) HSP 1 Score: 1155.97 bits (2989), Expect = 0.000e+0 Identity = 879/3287 (26.74%), Postives = 1588/3287 (48.31%), Query Frame = 3
Query: 3378 EHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEI----TTMTIR-----------LQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFG----KNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLL---STMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQ------------------------HIITMKSLDGEVVELRNQVLITSEVE------NWLGNLNNE-----MKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMI------HFTARCEELLNENNIITLKKELVKKL--NIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQ---------TVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQD----EHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYN-------------GLSNLKAIKNKAHFSVC------LIKGLGGNLNENSRETFALWVYEL----TDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNS--DTQQPFILSGPEGCGKSLM----LNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKF-TVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEW---------SVEVQDSLNDVW--FVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYS-RECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANES----GHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIP-REEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMV-----------AELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKT---GL---EKFDMRKFLTTEREQLEWKKEGLSSDEL-SMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSH--CCRPDLFKPQEWELF---TGTFISDKSDRNITVP-------------------------KWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNE-PILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKEL-----NSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANAL-FSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNF--YGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQ-LRILQRF-SVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKA--SLPDSLKRSSTDSPVVAFLQ-LERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPF-DYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF 12671
++F++E +F LEE+H ++ Q +W+ E+ + +++DW LFEE E L N + T M + L+++++ + +P++ +R L Q HW ++ ++ N E LTL +LD E H E+I+E++ +A E ++ ++++E F ++ + DS++ + ++ DI + + D+ + ++ S + + + W+ +L E + QR W+YLE IF + LP E F VD+ ++ IM VNR L + G+ + ++DQ+Q+C L YLE K +FPRFYF+ +D+LLEIL Q+ NP ++ HL+K F I ++F +Q I+ M S +GE V L +V + +E +WL +++N K +L L Y I + P I+ S I H++ +N NN+ L + ++ KL NI L +LI VH DI+ +++ S +EW+KQLR+Y CV++M ++ + Y YEY G + +LV TPLTD+CYL L + + LGG P GPAGTGKTE+ K L +Q +VFNC EG+D K MGR F GL + G+W CFDEFNR++ VLS ++ Q+ I++ K R + + + A FIT+NP GY GR +LPDNLK LFRP+AM P+ LIAEVIL S+GF+++K L RK+ ++ L E L+ Q HYD+G+RA+K+VL A L K D E+V ++++ALR + L K AD I F +++ D+FP +I + +Y L S IE+ + + + ++ KK++++YE + R GV++VGP+GSGK+T + +L+ L + + V+ +++NPK++ +L G ++ T EW DG++ RQ V+E WI+CDG +D WIE++N+VLDDN++L + + ERI+ ++ +FE DL+ ASPAT+SR GM+++ + V SW++K E + L D + L + +K+ + ++ V G + K H +C + +GGNL E E+F + +L D + P ++ +YY + R+ + E+ + + S+ L+ T D R F ++ + + +G G GKS++ L+ QK + + ++ SAQT+ + + + + +R+++++ D+N+PKLD +G+ I L+Q ++GFYD F +CS + GR+ ++ RF + I ++ L I+ K ++ + P + ++ + +E+Y+++ + SHY+F DL++ + +L+ D V D + + +E+ R+FQDRL++ + D FNTI SE S E +S ++ F+ G+ +P K + L ++YL D Y+ +++ ++ F + ++++++ R++ +P G+ LL G G G+++ + L HM K ++ RGY+ F+ DLK AGV+GE+ V L D Q + ++LE IN++L SGEVP L+ EE E +L + LA E+ G R + +YF R+++ LHI+L M F C+ P+ C++ W +W R+++L + ++ EG + + + S + ++ +L ++T Y+ I +Y+ + +K+ ++ ++ ++ G+KK+ E ++V +LK K+ + KL+ + Q++ ++A K+ +V+Q E K E + I A+ + +D+ L P ++ A+ A+ + SD+SE+R PP+++ ++E + +++G + W S + LG G +++ +D +I + ++++ + K + ++ S A + WV+A Y+ + P + + LE +++ + +++V+ +A + ++ A+ L + + A L L +E RW + + E+ + +AAA V Y + R E + W+E+ G+ + F + L E +W +GL D L ++E+ ++ L + + A W++ L+I+ D+NF LE +R G ++++EV + L+P L P+L QG R +++LGD IDY+ +F+ ++ T+ P P+ V+ +NFT TK+GL+ QLL+ ++ +P LE+++ L+ K +L +E+ +L+ L ++ GNIL+++ L+ +LN++K +S IS L+E+ + + + R+ + P+A GS ++FV++ L++++ MY++SL F +LF + +SE + D R L+ + VY V R +F+ D+L+F+ + + ++ +EW F TG ++ + VP ++ A T+++ NL + + DDD + E P+S +++L+ F++++ I+A + +++ A F C+ L + S++L ++E+ +SN P++ I+S G+DP + + +ER +++GQGQ + L+ S+NGDW+ L+N HL SW+ +E + N + H+DFRL++++ P F +LQ+S+K+T E P G++ N R++ D G R L F + +FHAIIQER+ F P GW YEF+ +D E L + + NI W + + +GGRV + +D R L++ + R+F+ ++ + F G P S DY ++ L + P F + +N + + Q + Q+I L + R S G K + +I + +L + L L++ KA SL ++ + +S Q ++R+N+ L+K + +SL L K +KG +++ E+ + L Q P++W +P +++ L+L+ VE+W + F P FL Q AR + +D+L F
Sbjct: 633 KNFKVEVTKFEELEEVHAELRLKQSLWNSLVEW-----DQSQQDWTE-----TLFEELNP---ETLSNNVMKYAKTVMQLEKGLPPNSVVPILKEKLENMRHKLPVITNLRNPALKQRHWDQIQQIFNY-HFKDEEPLTL-GLLDKI-EAFEHTESIEEVSGQASSEASLEGILKKVEDAWKSTEFIVLPHRDSKD--VFILGGVDDIQAVLDDSMINVSTIAGSRHVGPIRPRVEEWQRQLYLFSETMDEWMTCQRNWLYLESIFSAPDIQRQLPAEAKMFMTVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKC---LEAYLESKCVIFPRFYFLSNDELLEILSQTRNPHAVQPHLQKCFDAIAKLEFGSTVQAPSTPQDQPVTPTGERRKMRYATNDILGMISPEGEKVSL-GKVSYSHSIETLTLCFSWLKDMSNHPLNLHKKISLFSSLMY--------------ITWSRSPQYIITSSTTINALFPSHYSLCIVFPMNLNNLAALVRGVLPKLTRNI--------------------LGALITIDVHARDIVTGMVNAKVDSENNFEWIKQLRYYWDPDLDNCVVRMSNSMYIYGYEYLGASARLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAKQCVVFNCSEGLDFKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLLTIRNAKVAKASRFMFEGREIKLVPSCAAFITMNP---GYAGRTELPDNLKALFRPMAMMVPNYALIAEVILYSEGFESSKNLARKMTQMYRLCSEQLSQQDHYDFGMRAVKSVLVMAGAL--------KRSNPDLEEDV--------VLIRALRDSNLPKFLAADAILFRAILTDLFPGKEIPDHDYGKLQSTIEDCMVAKGLQAIPALVKKVIQLYETMIVRHGVMLVGPTGSGKTTNYMMLQDTLTSLHEQAEDSPYYLPVQTHILNPKSVTMGELYGEVNKLTMEWRDGLMALKVRQCVQETTPDHKWIVCDGPVDALWIENMNTVLDDNKMLCLANSERIKLNNTIHMLFEVQDLAVASPATVSRCGMVYMDPNELGWRPFVRSWMQKHSDKMKEETREYLWNLFDHYVDAGLKFASKKCTQAMQQVDISKVTTMCCLFDSFFFPAKGGPDFNLDPTKLHPLICTAFLFVFLWSIGGNLVETCNESFDTFTRDLFADTHDVRIP--GSGDLYSYYVDFDTRRMEPW----EKIIPAFKYSSEVPYFDLLVPTVDTVR----FGFLMDKLLSVNKSVLYTGTTGVGKSVIAKAILDDISQKSNYMAIM-MNFSAQTSSQRTQEMIETK---LEKKRKNILGAPAGKRMVIFVDDLNMPKLDTYGSQPPIELLRQYQDFRGFYDREKLFWKEIHDMTICSACAPPGGGRNPVTPRFLRHFSMFCIPSSAEHTLGHIF----KSIVSGFLLDFPAEVRECADAIVGAS-VEIYARMSTDLLPTPAKSHYVFNLRDLSKCIQGVLQADPGVIRDKGQI--FRLFCHEASRVFQDRLIN-----KEDKTFFNTIMSEMAHKHFQQARSPEKFESNPILFGDFMKMGA-DPADKLYEELTDLKKVKNLLTDYLDD--------YNMNSSKEMKLVFFMDAIEHISRIARMVRQPRGNALLVGVGGTGKQSLTRLACHMSAYKCFQIELTRGYDYSAFREDLKKLYDVAGVKGENTVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEPEEYEAVLNGTRPLAKEAGIPEGDRDGVFDYFISRVRNNLHIVLCMSPVGDAFRTRCRMFPSLVNCCTIDWFTEWPREALLSVSSNFFEEVDLGAEGVKDKVAEMCVEIHTSVSTMADRFYAELRRRY---YTTPTSYLELITLYLSMLDEKRKQLIGARDRVKNGLKKLLETNDLVDTMQVELVALEPQLKQKSLDVEKLMEKLQVDQEEA-DKVRNVVQAEEAVAKE------KADETSAIAAEAQKDLDEAL----PALEAAQKALDSLDKSDISELRVFTKPPELVMTVMESICILLG-VKPDWPSAKTMLGDAGFLKKLMDYDKDKIPDSTLRKLKKYIDNPKFVV--EVVEKVSKACRSMVMWVRAMDLYARVYRTVEPKRAKLAAAQAELEVVMSTLREKQASLAEVESKIAELQAAYDHSIAEKETLTKNIAQTAARLKRASKLTTALGDEQGRWTENVAAFELEIGNVVGNVFVAAACVAYFGAFTSLYRHELINSWIEQCKELGVPVSDDFSLINVLADPYEIRQWNSDGLPRDSLKAIEDRILKLLNMRSTLFL----KANRWIRTKEAKNGLKIIKLTDNNFLRTLENCIRIGMPVLLEEVGESLDPALEPILLKQTFVQGGRLLIRLGDSDIDYDKNFRFYMTTKLANPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLERPDLEDQRNQLIVRINSDKNQLKAIEDRILKLLFHSEGNILDDEVLINTLNESKVTSGVISTRLKEAERTEEKITIAREKYRPVATRGSVMYFVVASLAEVDPMYQYSLKYFKQLFNACIESSEKTDDLDRRLEILLNNCTESVYVNVARGLFEKDKLVFSFMLCGDIMRQQEIITDEEWNFFLRGTGGLDKERPAKP-DVPWLTDFMWNTCCDLEDVLHSFKGFKGDFVKAPITISMGNLQQS--------EVGDDD-----------QAEKPRSWQDRLTSFERLIFIKAFKEEKVVFAAVDFVCENLGKTFVESPSIDLPVLFEN--VSNMIPLIFILSTGSDPMNAFLRFARDMNYTERIQAISLGQGQGPVAEKLIANASKNGDWVFLQNCHLAASWMLAMETTIKDLTNNEAEVHEDFRLFLSSMPTKAFPVTVLQNSVKVTNEPPKGLRANTKRAFGELMADPFESHVLGVRWRKLVFGICFFHAIIQERKKFGPLGWNIKYEFNDSDRMCALENLKMFL--VDENIPWDALTFITGQITYGGRVTDEWDQRCLTTILGRFFSPKILEDNYKFSESGIYFPPGFESLHDYREYVDNLPLTDEPEVFGMHENANIAFQTQETHQLIYTVLEVQPRLASSGGGKTNDEIVYELADSILGK---LMDVLDMEKAEKSLFETDAKGRYNSLTTVLGQEVDRFNN--LLKVIKNSLTQLQKAIKGLVVMSLELDKVYTSFLNNQVPDMWANSSYPSLKPLGSWVKDLVLRTMFVEQWIIHGPPKSFW-----ISGFFFPQGFLTGTLQNHARKYNLPIDQLTF 3754
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Medaka
Match: DYNC2H1 (dynein cytoplasmic 2 heavy chain 1 [Source:NCBI gene;Acc:101163989]) HSP 1 Score: 3454.07 bits (8955), Expect = 0.000e+0 Identity = 1768/3421 (51.68%), Postives = 2419/3421 (70.71%), Query Frame = 3
Query: 108 EDQRKDTIFLITKSHFPNQNSKFVNEEC-LDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDT------DPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDF---IHRSRQGKVPP--TKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVK---SVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKIVNLMGIDLLRQQQKWKDTLNEIRQILFQIENQKHLPENTLPWKRHLDHQLYKALEYQYHIGLEALNENLPEIRVDLVYRQGRLQFNPTFEEIKSKYFKEMKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRN-AEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSL--SADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFET-KLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXX--XXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIV-ELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQ 10304
ED RK + T + F + + +N+E L+ F D+ + VL ++ N SN++ N LVF K P++IT +N++ ++++++ E+PI++LY ++ ++ P+LL D DPK+ L+SELE GLGS++R +K S + GI + DE FW + L ++ + + R + + +E + + + SL++ +E L+D+W+ P YP++RM LM++I L R +Q +L+ +E+ +A V+++L AI +C HW+ C+ L + WK+Y PH W + S + RL E+ +LR VHE++ ++P ++Q + F+ F+ + PL YNPYTEP+WK AV +F R I P+E + RLK + + PQQLL++FQ++ +LI RP I+ L ERE LLA+L+ + K +F H K P +N + ++K+VW +QL K+ + + I +L DL GF+ F+ + E + + QEQFE W++++ L D + + R+M+L DG L ++YSDRLV+L+REVR LS LG+ + + AA+ KFY +A+ILKQVA FYNTI+ QMIP Q+ MML A+ FE+++K S+ +S K + W+NP+EL +I KLQ A+ + ++NR LRK H +K+V+LM +DLLR QQ+WKD L E+R +E Q ++ W+ H +HQLYKALE+QY GLEALN+NLPEI++DL+++QGRLQF P FEE++ +YF+EMK+FI++PNQFKG+ S G +LIF +I++NA+GF+ + KAE LF RL A +KFKEW++LG +DLE+ V+++ + D+E+NFKA+K +GKE+E+LP++ K+DCITVNC P+K ++D LIQ +FD LL SLRK+I+G + ++D++++ S++ LS RP ++EI A + + + + Q +E+ N LLR VAG G D++S L+ KWDK EL+MES Q+M++EQ+EVM+++ R ++ D+ +F RW LKP + L+ G A L +Q I+DK+ E +EL ++++ L +DC +F ++P +F++ EEI D+++ WS +EE+Q G + A EDW++FRS+ Y+FEEFL W ++LR + T+M+++LQ E+D YK+++P+LK++RGE LSQDHWL+MFR+L +PRG TLE LT +L A I+ A+ +K+LN +AQ EVTIREA+REL+LWGA A F L EY DS +ISLIK+WRD++SQVGDN+CLLQSLKDSPYYR FQDK ++WE +L+DLDEYL NLN IQR+WVYLEPIFG+ ALP+E++RF+RVDEDFRSIMSD+ R+ RV+SL S +G+K+ L ++DQLQRCQK+LNE+LEEKRS FPRFYFIGDDDLLEILGQ+TNP VI+SHLKKLF GI+ V F++ QHI+ M SL+GEVV LR V I+S VE WLG L+ +MK TL L L ++ N ++ +YPSQILCL+E I FT E+ L + ++ L+ EL KL YT + S ++ ++ LKLK+LILD +HNI ++ QL S +W W KQLRFY D+ C IQMVDA+F+YTYEYQGNA KLVHTPLTDKCYLTLTQ M MGLGGNPYGPAGTGKTESVKALG LFGRQVLVFNCDEGIDVKSMGRIF+GLVKCG+WGCFDEFNRLEEAVLSAVSMQIQ IQD +K+ LL + V++D NS +FIT+NPAGKGYGGRQKLPDNLKQLFRPVAMS+PDN+LIAEVIL S+GFKN + LG KLVA+FNL+RELLTPQQHYDWGLRALKTVLK +LL+ + + D + E+ L+VQALR+NT+SKLT+AD F++L+KDVF +D ++E L A+E+V +E + + GQ KK LE+ EQLRQRMGVVIVGPSG+GKST+W++LR AL+ G+ VK Y MNPKA+PR QLLGHID+DTREW+DGVLT+SAR VV+EPQE+ SWI+CDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNF+FETHDLSCASPATISRMGMIFLS E DV +L+ SWL+ Q + + L +L D+F ++LDW+ K+N+F + TS VGTV+N LS+L A+ + F V L++GLGGNLN +R+ FA + E P+ K L+ Y++ K + L Y+++ E L+++Q S +L P+I T +QR L F WL + +QPF++ GPEGCGK ++L + F +L+S QV +HCSAQT+ HVLQKL+Q C++++SNTGRV+RPK+ E L+LYLKDINLPK DKWGTS L +FLQQ +TYKGFYD NLE+V L+ +Q+V SM++ S+ SL++RF SIVR+C+I YP ++QL+ IY+AYL+PVL+ + W+ + LA +M+++Y Q+K+KFTVDD+SHYLFTP LT+WVLSLLRYDL N S+LE+++YE+ R+F+DRLVSS D +L + I +WS + D++ D ++VTWG E P+ GK LG+L S L++ I +G++ Y+R+ ++LD++LF EV D V+++DRVL++ GGS+LLAG+SGVGR T + LVSHMH L + K+ RGY LK F NDLK +Q AG++G+ +VLLLED+QF+ P +LE++NSLL+SGEVPGLYT EELEP+L LKD A++ G G L NYF+ RI+ LHI+LIMDCSN NF INC+SNPAF++ CSVQW+E WS SM KIP +L++K E+G + +L FL +H++C +T Y+ F+ +Y +Y +KKN++ TRQ H+Q G+ K++EAK +V +LK +AAEQS LL KQ EAD AL++IT+ MQ A+++K EMEK+ K E + +RKA I+DEL ++P V +A+ AV +IK LSEIR+LR PPDVIRDILEGVL +MG DT+WVSM++FL KRG++E+I TFDAR IT E R VEELL R K SFDPKNAKRAS AAAPLAAWVKANV+YS+ LE+I PLE EQ L NL E + LE +++V V ++ F++ TA+AAKLE E+ A +TI+AAE L+ +L E RWN Q++ E+ EL L ++LLA+ + Y+ ++ ED+R+ ++ WM ++GL+KFD+R FL +E EQL WK +GL SD+LSMENALVILQ + PFLIDPSS AT WL+ H K+ KLE++NQQD+NF T LEL+VRFGKTLIIQEVDG+EPVLYPLLR D I+QGPR VVQ+GDK+IDYN DF+LFLATRNP +PPDA ++V+ VNFTTT+A K +
Sbjct: 6 EDARKRFLLNTTGNFFAVKPASTLNDEAELNNFLDDENEFVLSIRRRGNDLQLSNKVTQE----NVLVFFKLRPTVITEENLHQNLLISSMLESPINTLYQAVKQVFAPVLLKDERWRSAFDPKLAGLLSELELGLGSVVRSSGAKSS-------VKEGILTPTDEFQFWREVLESAQKNSVRERATYFTEQFKTIQKEYEGLDALSLSDVVELVEQSRETLDDVWRQTEFQP-YPEARMVRLMDVIGGALGRYVQRKLSDSKVFEEPFASVRDNLRMAISICEHWVTGCEFLTGQAWKKYSPHPWKGSKHCPQS-LDCLLKRLNEVVTLRVVHEKLLCLVPGGKQQALTSDRVFEPFIGLNPLHYNPYTEPLWKAAVAQFERLITPSEQEVAGRLKAYIADVQ--DNPQQLLQVFQKHKELIRRPTINKELQTEREMLLARLLDYNKGTNSNFENCCHGGPGDKSGPLSGRNLPEVVNKVVWVRQLTHKVEDSVRIAKALLSDLSGFKTFVHFCDDLSEVLKAYEQEQFEDWSRDILSGLADPKSG-----ISSRVMDLDHADGRLKIHYSDRLVSLLREVRQLSALGFPVPAKIQQAANTADKFYREAIILKQVANFYNTIDQQMIPSQRPMMLSLALAFERVIKNPRSLSKESGGKLQITWDNPKELEGYIAKLQSAAEKLSTENRKLRKWHTDFIDKVVSLMNVDLLRHQQRWKDGLQELRTGFATLEAQGFRSDDMRAWRLHWNHQLYKALEHQYQTGLEALNKNLPEIQIDLIFKQGRLQFRPPFEEVRVRYFREMKRFISIPNQFKGV--SVQGEELIFTIMIDKNASGFLTIFSKAEDLFSRLQAIHHKFKEWVVLGQVDLEKLVEKNLTSVQDWERNFKALKARGKESERLPSQEKVDCITVNCEPVKSTIDDLIQRLFDMLLLSLRKSIQGHLQAIDSFVSESMEALSTRPDNLEEIGAANSKYNQILSRKPEMLPQFQCAEEKNRLLRAVAGAGFDSLSSLRSKWDKLELVMESHQLMIKEQVEVMRSHAAGRISTYRADLERFQLRWDQLKPKDENLEGGDHAALLACLQTIRDKQQEFQELELVRSKLLEDCTYFDLDPPDFSMAEEIKVDMEELSQTWSLYEEWQQGFTDKAHEDWITFRSKTYVFEEFLLTWQDRLRKLKQPTSMSVKLQGEVDKYKNMVPVLKYVRGEHLSQDHWLDMFRMLGLPRGTTLERLTFSDLLAVADTIVEKAKELKDLNSRAQAEVTIREALRELDLWGAAASFTLTEYTDSSGRTISLIKDWRDVVSQVGDNRCLLQSLKDSPYYRSFQDKVSLWEVRLSDLDEYLLNLNAIQRRWVYLEPIFGRGALPREEARFKRVDEDFRSIMSDIQRDTRVVSLSSRAGIKSSLVAILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQATNPSVIQSHLKKLFAGIHSVVFDEQCQHIVAMCSLEGEVVPLRTAVRISSLVEVWLGELSVQMKETLKHLLYECLMAVKKGN-----VDPLRYPSQILCLAEQIQFTEDVEKALKQQHLHQLELELNSKLEHYTRVDTNSDDSPNTESVILQLKLKALILDIIHNISMVKQLNQAGVTSTDDWAWKKQLRFYM-GPDKFCHIQMVDAQFSYTYEYQGNAAKLVHTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQAIQDSLKHHKNICELLGKEVSLDPNSGVFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSKPDNELIAEVILYSEGFKNGEMLGGKLVAVFNLARELLTPQQHYDWGLRALKTVLKACGSLLQQQRRR------------PDKEKESNSLVVQALRLNTMSKLTFADSSRFDALVKDVFTGVDFTDVEDQILIHALEQVYQEAQLELIPGQLKKALELNEQLRQRMGVVIVGPSGAGKSTLWRMLRAALSMTGKVVKQYTMNPKAMPRQQLLGHIDMDTREWADGVLTHSARCVVREPQEVNSWIVCDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSCASPATISRMGMIFLSDEDIDVGALMKSWLRGQSDECRSQLENWLGDYFQRALDWVFKQNDFVVETSLVGTVFNALSHLSAVNERGEFLVGLLRGLGGNLNLKTRQEFAKELLSWAREPPPDARKP--LDTYYDNKSDHLAAYTFQHPESLTLEQF-SHAHML-PVIKTTGMQRGLHGFFPWLTASHRQPFMVVGPEGCGKGMLLRYAFSQLRSTQVAVVHCSAQTSSRHVLQKLSQTCLLLSSNTGRVFRPKDCENLVLYLKDINLPKPDKWGTSNLTAFLQQALTYKGFYDENLEWVSLENIQVVASMSTGGSVCSHSLTSRFCSIVRICAIDYPDREQLHSIYSAYLQPVLQHSLGSQAGWASTGRTHQLAGSMVQLYEQVKAKFTVDDHSHYLFTPCILTEWVLSLLRYDLTAAQSNLTQSVLEVIAYEARRLFRDRLVSSKDLHTFDNMLSSVIRGDWSSDALDNMADGFYVTWGCSEGTVMAPCQPLPPHGKQLGRLDSSDLREVIQKGVMLYNRDNKELDLLLFWEVCDFVSRVDRVLSRLGGSLLLAGRSGVGRHTAACLVSHMHGYALFTLKICRGYTLKHFSNDLKMVMQLAGLDGQQVVLLLEDYQFVHPSFLEIVNSLLSSGEVPGLYTPEELEPLLSPLKDSASQDGFSGPLYNYFSHRIQQNLHIVLIMDCSNSNFTINCESNPAFYRKCSVQWMEGWSESSMKKIPELLLSKT--EDGGINVREK---------HGDLCRLFLMVHESCKEHGATPSQYMAFLHVYTSLYSRKKNQLTTRQQHLQAGVSKLNEAKALVDDLKRRAAEQSALLKTKQQEADAALQEITTSMQNASDQKTEMEKIKEKMAVEVSKIEERKAKIEDELKEVQPLVDEAKRAVGNIKPEALSEIRSLRMPPDVIRDILEGVLRLMGIFDTTWVSMKSFLAKRGVREDIATFDARNITPEIRQSVEELLNRNKASFDPKNAKRASAAAAPLAAWVKANVQYSFVLERIGPLEKEQAGLLENLRKTENRKNKLEDQLNNVGAKVNKLKEKFQRHTAEAAKLEAEVTKAQDTITAAEQLISQLVGEHTRWNAQVMSEIKTELDTLPFRTLLASGFITYLSAASEDRRRHCLETWMSQSGLQKFDLRSFLCSESEQLIWKSQGLPSDDLSMENALVILQSVACPFLIDPSSRATEWLRTHLKEHKLEVINQQDNNFMTSLELAVRFGKTLIIQEVDGVEPVLYPLLRRDFIAQGPRYVVQIGDKVIDYNEDFRLFLATRNPSLFIPPDAASVVTEVNFTTTRAAHKAK 3371 HSP 2 Score: 833.173 bits (2151), Expect = 0.000e+0 Identity = 418/834 (50.12%), Postives = 573/834 (68.71%), Query Frame = 3
Query: 10557 EERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVAI-----------SNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGN---------FYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNII--KASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVE-KWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLK 12989
+ERDA+LPLAE S ++FVI+DLSKINNMYRFSL SFLRLFQRAL + ++ +R +L A L+ +VYEYVCRS+FK+D+LMFA+H P+LF EWE+F G+ + + T +W ++ + + S + P L+ L + D DLW F +SS+CE+EIP S+ K+S FQ++L++QA+RPDRLQSA++ F L +K LSP +NL ++Y +ET+ EP+LIIISPGADPSQ+L EL+ + I +MGQGQAD+ L L +CS+NGDWLCLKNLHLVT+WLP LEKELN L+PH +FRLW+TAE H F ILLQSSLKITYEAPPG+K NLLR+Y++W+ + ISK GS RA +LF LAWFHA+ QERRN+IPQGWTKF+EFS++DLRAG +I+D++ ++ + +QW F+HGLFE+AI+GGR+DNP D+R+L SY+K++F+ ++ G F +I LPS+ S DY +I L + + P+FF LP NI+RSSQRIISSQVI QLRI+ R G+KFD+++WS L+P+LN WK LNQG ++I K P +R SP+++F+ LE++N+I++++ +H SL +LSKV++G++LLT EVQ L+ LL + P W +WEGPEEP Y+R ++ +A A++ W E + + LLS ILDL ELFHPDTFLNALRQ TAR++ SMD L FV W AK +++G L +EGC FDG ++E S S+ +P + WV + + ++ I LP+Y R K+VT I +PC WIQ+G ALFLK
Sbjct: 3406 KERDAYLPLAESASKMYFVITDLSKINNMYRFSLASFLRLFQRALQAKKEEGNTEVRIAALQANLKNMVYEYVCRSLFKADQLMFAMHFVKGMHPELFLENEWEVFVGSIVGEIKTTFRTECRWSLSNYGLNLVFSFIVLPFLTSLFQATFPALYQTLCLSDSDLWLSFMQSSQCEQEIPSSIAKKMSRFQQVLMVQAVRPDRLQSAMTAFASHALSMKELSPPPLNLRRLY-AETMEWEPVLIIISPGADPSQELAELAAETI--------SMGQGQADVALGTLRECSRNGDWLCLKNLHLVTAWLPHLEKELNILRPHANFRLWLTAEVHPKFPPILLQSSLKITYEAPPGLKKNLLRTYESWTPEQISKGGSLARAQSLFCLAWFHAVCQERRNYIPQGWTKFHEFSLSDLRAGFDIIDRLF-EAGKTVQWDFVHGLFESAIYGGRIDNPADLRILRSYLKQFFSAQFLSSVGQRNSREEGNVFPPQIVLPSSCSILDYRRVIENLPEDDRPAFFGLPANIERSSQRIISSQVISQLRIVSRLVATGSKFDRELWSSSLSPILNLWKKLNQGSSLIHQKVDPPVEGQR----SPILSFIVLEQFNAIRMIQSIHQSLAALSKVIRGTQLLTPEVQKLATALLNQECPITWQNKWEGPEEPMQYLRAVVTRALAMQVNWVERASRQALLSNILDLSELFHPDTFLNALRQETARSLGCSMDSLVFVSSWKSPLAQAKLQIQVGGLQLEGCRFDGVHLSENQHHSPSVSAVPTCYMAWVLQVPFYHPASEEKIWLPLYTSSERVKVVTHIPLPC-GANASHWIQTGAALFLK 4224
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Medaka
Match: dnah5 (dynein axonemal heavy chain 5 [Source:NCBI gene;Acc:101171908]) HSP 1 Score: 1119.38 bits (2894), Expect = 0.000e+0 Identity = 897/3259 (27.52%), Postives = 1569/3259 (48.14%), Query Frame = 3
Query: 3609 LQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIK--EWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIF--GKNA--LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMS-GMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDI-QHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGIN-ADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIY----TNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLE-RRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLK--GAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVY---NGLSNLKAIKNKAH----------FSVCLIKGLGGNLNENSRETFALW-----VYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTP---LILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKL-KSVQV-TTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY--DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYT-----------AYLKPVLKRLIPK-----HPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVE---VQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKL-----TSEYLKDTIDRGLLQYSRECR--DLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSL-----KDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAK--PKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIM-------------GTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMK----DLEKGVSDVDKAVAG---YRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEK--------FDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVAIS--NLASAMPELWSVLNIKD-----DDLWHQ-FAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWL-PVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIK--KSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQ--RFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVA---FLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIK-ISMDELKF---VCRWGGSNV--SAKYSVKIGNLHIEGCLFD--GTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPC-------QSGQQDKWIQSGVALF 12983
L++ ID + + P+L+ + + + HW + + + E LR+I++A + +++ E I+++ A E I + ++E+ F + +N L++ ++I+ + D+ +L SL + Y F+ + W L++ + +++ +Q W+YLE +F G A LPKE F +D+ + IM+ + V+ C M LL +++QL CQK+L YLE+KR LFPRF+F+ D LLEILGQ+++ I++HL +F I V F++ I I+ + S + E +EL + VE WL L E + +L + A L + N+ I+ + + +Q+ L + +T EE L + + ++ K N + N + ++ V K ++LI VH DI D L + + +++EWLKQ RFY I + D F+Y E+ G +LV TPLTD+CY+TL Q + M +GG P GPAGTGKTE++K +G G+ V+VFNC + +D + +GRIF GL + GSWGCFDEFNR+E VLS + QI I+ K++ + + V+++ IF+T+NP GY GRQ+LP+NLK FR V+M PD +I V L S GF + +L K ++ L E L+ Q HYD+GLR + +VL+ GAA + SD E+ ++ + L+ LSKL D F SLI+D+FP I++ + Y L +AI++ I+E +++ K++++YE R R G++ +GPSGSGK+T ++L A+ + GQ + MNPKAI Q+ G +D+ T +W+DG+ + R+ +K + WI+ DG +D WIE+LNSVLDDNR LT+ +G+RI PN +FE H++ ASPAT+SR GM+F+SS ++ WLK++ ++ +L F + + + EF + + N L L +K + + L+ G L R+ LW V + + P ++ + +YY + V +S EE + +TP IL ++ F I S + +L G +G K++++ K +Q+ L+ S+ TTP+ + Q+ ++ ++ G Y P +++ + + DIN+P +++WG ++Q++ KGFY + EF + VQ + +M R + + + PS ++ I+ +++ V +R IP+ +W Q +K+K+L +KF HY+F DL++ +L + V N+ LL + +E R+ DR D + D L + + E V D + +FV + P+A G P + K+ + E LKD ++ L QY+ R +D++ F++ ++ K+ R++ PGG+ LL G G G+++ + L S + K+ + R Y DLKS + AG +G+ I + D++ E +LE +N++L+SGEV L+ E++ IL L ++ +L +YF R++H LH++L F PA C++ W +W +D+++++ + ++ + Q+ + Q ++ YFL + V T + Y++FI+ Y IY++K+ E+ + G++K+ EA E VA L + + K L +AD LK++T + + K E++K+ K + KA +++L P +++A A+ IK SD++ +R L PP +I ++ VLL++ + +SW N + E++ F I E+ ++ +++ + A+ AS A L +W KA + +++ P LK NL E ++ DLEK +++D A R ++E+ + L + K + A +L+ L E ERW +Q E A+ L LLA A + Y S P +Q + L + L++ D+ + L EW +GL +DELS+ N +++ + P LIDP + W+KN +L+I + F LE S+ G+ L+I++V + L+PVL +L + I G V++GDK +D FKL++ T+ P P P+ A S ++FT T GL+ QLL + K ++E+ +T+LL++ K ++ ++E++LL L + G++++++ L++ L TK+++ ++Q L+ + Q+ ++ R+ + P+A GS L+F+I+++S +N MY+ SLT FL LF +L S S++++ R S+I + VY Y R +++ + +F L ++ E T I + ++ A+ + +S NL + +LW I D + LW F K + E +P S ++ L F+++L+I+ PDR + ++ D + K+ +++ +E E+ P++ +S G+DP+ + L K+ RY V+MGQGQ LL + NG W L+N HL +++ +++ + + + FRLW+T E H F LLQ S+K T E P G+K L R+Y ++D + + + L+ +A+ H+ +QERR F P GW YEF+ AD A + + + + + + W + + +GGRV + +D R+L+++ K +FN ++ NFY +P +S YLA I L Y++P F L N D + Q + V+ + +Q S G + + SR + +L + + +P +KR P+ FL+ E +++ V S+LI L + G+ ++++ +++ +C+ + P W++ W F + L+ + + + W + T F+P FL A++Q AR K ++D + V +W ++ V + L++EG +D +TE S VL + V W+ Y+E++++ P Y K T+ DI C + + W+ GVAL
Sbjct: 966 LKRTIDEFSECCPLLELMTSKAMMARHWKRITEVTGHNLDVESENFKLRNIMEA--DPLKYKEEIEDICISAVKERDIEQKLKEVITEWDNKTFTFAGF---KNRGELLLRGDSTSELIASLEDSLMVLGSLMSNRYNTPFKAQIQKWVQYLSNTSDIIEHWMIVQNLWIYLEAVFVGGDIAKQLPKEAKLFSSIDKSWMKIMTRAHEMPNVVQSCVGDVTMGQLLPHLLEQLDSCQKSLTGYLEKKRLLFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVQFHEKIYDRILAVSSREKETMELDRPITAEGNVEVWLNALLKESQRSLHLVIRQAA--LAIQNEGFELIDFLNSFSAQVGLLGIQMIWTRDSEEALTNAH---YDRGIMSKTNQHFLNLLNTLIDMTTKDLGAVERTKYETLITIHVHQRDIFDDLCRLHIDNPSDFEWLKQCRFYFNEDSDKMTINITDVSFDYQNEFLGCTERLVITPLTDRCYITLAQALGMCMGGAPAGPAGTGKTETIKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIAIVLTCKKDRHKTFVFTDGDSVDMNPEFGIFLTMNP---GYAGRQELPENLKINFRSVSMMVPDRQIIIRVKLASCGFIDNVKLACKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAA------------------KRANPSDTESTIVKRVLKDMNLSKLIDEDEELFLSLIEDLFPGIELNKEGYPELEAAIDKKIQETGLINHPPWKLKVIQMYETQRVRHGMMALGPSGSGKTTCIQILMKAMTECGQPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLKAKKGEHIWIVLDGPVDAIWIENLNSVLDDNRTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMSSSVLGWSPILEGWLKQRSPNEAEVLRQLFSSSFSELYRFSVQSLEFKMDMLEAFVIMQCINMLQGLIPLKEQCGELPREHLERLYIFALMWSAGALLELEDRKKMELWFRGNDVIRRSLPEIPPGREETMFDYYVT-AEGHWVHWSTRVEEYIYPPD-------VTPKYSSILVPNVDNVRTDFLIDTISKQGKAVLLIGEQGTAKTVIMKSFMSKYDPEIQLGKCLNFSSATTPL-MFQRTVES--YVDKRMGTTYGPPAGKKMSILIDDINMPVVNEWGDQVTNEIVRQLMEQKGFYNLEKPGEFTNIVDVQFLAAMIHPGGGRNDIPQ-RLKRQFSIFNCTLPSNASIDKIFGVIGEGHFCAQRGFIEEV-QRTIPQLVLLTRRLW-QLTKIKMLPT---------PAKF------HYIFNLRDLSRIWQGMLCTNAEVI--NSVHVLLALWKHECKRVIADRFTMPDDVEWFDQTLAKLVEQQLGEEHKKVVDCGVERYFVDFLRDPPEATGEEPEESDFDMPKVYEPIESFESLKDRLNMFLCQYNDSIRGNGMDMVFFQDAMIHLIKVSRIIRTPGGNALLVGVGGSGKQSLTRLASFIAGYKIFQITLTRLYNTTNLMEDLKSLYRIAGHQGKGISFIYTDNEIKEESFLEYMNNVLSSGEVSNLFARNEMDEILSDLVPVMKREFPRRPPTNENLYDYFMSRVRHNLHVVLCFSPVGEKFRNRALKFPALISGCTMDWFSRWPKDALVEVSHHFLSAFDIDCSPQVKSEVVQCMGSFQDCVAEKCVDYFLRYRRSTHV---TPKSYLSFIQGYKTIYVEKRAEV------MNTGLQKLKEASESVAALSKELEVKEKELQIANEKADMVLKEVTVKAEASELVKVEVQKVKDKAQAIVDSITADKAIAEEKLEAARPALEEAEAALQTIKPSDIATVRTLSRPPPLIMQTMDCVLLLLRRRVNPVEINAETNFITSSWQESLNLMTSGSFLSELKQFPKDTINEETVELLQPYFNL--PNYNIERARTASSNVAGLLSWTKAMASFFAINKEVLP-------LKANLAVQENRLAVANLDLEKAQAELDAKQAELNVVRAEYEEAMTEKLTLLEDAKRCRRKMQIASNLISGLAGEKERWTEQSKEFAAQTKRLVGDVLLATAFLSY--SGPFNQEFRSLLLNEWQCELKQRSIPFGNNLDITELLIDASTVSEWNLQGLPNDELSIHNGIIVTKAARFPLLIDPQTQGKTWIKNKEAKNELQITSLNHKYFRNHLEESLSLGRPLLIEDVGEELDPVLDNVLEKNFIKTGSTYKVKIGDKEVDVMKGFKLYMTTKLPNPAYTPEISARTSIIDFTVTIRGLEDQLLGRVILTEKREMEKERTDLLEDVTYNKRKMKELEDNLLYRLTSTQGSLVDDESLIVVLGNTKQTAEEVNQKLQIAGDTQIQINAAREEYRPVATRGSILYFLITEMSMVNVMYQTSLTQFLGLFDLSLARSSKSSNTSERIKSIIEYMTFKVYYYAARGLYEEHKFLFTLLLTLKIDMQGKNVTHKEFL--TLIKGGASLDLKTCPQKPAEWILDMSWLNLVE-LSKLWQFSEILDQISHHEKLWKSWFDKEAPEEEVLPNSYQS-LDCFRRLLLIRCWCPDRTIAQARKYIRDAMGEKYTEGVILDVEGTWE-ESNPRTPLICFLSMGSDPTDSIIALGKKLKIETRY--VSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLNFMDELMDTVIETECINDSFRLWITTEVHKNFPITLLQMSIKFTNEPPQGLKAGLKRTYGGINQDLLDVSNTNQWKPMLYCVAFLHSTVQERRKFGPLGWNIPYEFNQADFNATVQFIQNHLDDMDTKQLVSWNTVQYMIGEIQYGGRVTDDYDKRLLNTFSKVWFNKNMFERDFNFYKGYGIPKCSSVDQYLAYIQGLPAYDTPEVFGLHPNADITFQSKQAKDVLDTILSIQPKDSSSGGGETREAAVSRMADDMLEK---------LPPDYIPFEVKRLQKMGPLKPMNIFLRQEIDRMQRVIMLVRSTLIDLKLAIDGTIIMSENLRDALDCMYDARIPARWMKSWASSTLGFWFTE-LLERNRQFQTWLFKGRPNCFWMT-----GFFNPQGFLTAMKQEIARANKGWALDRMVLCNEVTKWMKDDIPHPPAKGVYVYGLYLEGASWDRNNCRLTE----SKPKVLFEMMPVIWM-------YAENNVVKDPRLYSCPIYKKPTRTDINCIASVGLKTTQPPEHWVLRGVALL 4109
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Medaka
Match: dnah12 (dynein axonemal heavy chain 12 [Source:NCBI gene;Acc:101164478]) HSP 1 Score: 1007.67 bits (2604), Expect = 0.000e+0 Identity = 874/3301 (26.48%), Postives = 1542/3301 (46.71%), Query Frame = 3
Query: 3615 KEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLE---ALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKN----ALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSE----VENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLAL---NKIG----QTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKK-----QDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNK----------------AHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPE-------------MNKQNVLNYYFNE--KQNRLVTYSYECEEELSIDQLMS-DKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSL-----MLNH----CFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYD-SNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKR--LIPKHPIWSQNSKVKLLANTMIEVYSQ-LKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTS----------------EYLKDTIDRGLLQYSRECRD-LDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTL-QTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRG------SLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALK--KITSVMQGATERKGEM--EKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIK-SSDLSEIRALRAPPDVIRDILEGVLLI-----------MGT---MDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVE-ELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKT------GLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXX--XXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKL-------VYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWE------LFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSV-LNIKDDDLWHQFAKSSE-CEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEK---ELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSY--DNWSE-DFISKTGSGTRA--NALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVV-------NGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHG--------TKFD--KDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPF-DYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNVSAKYSVKIGNLHIEGCLFD--GTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKID---------IPCQSGQQDKWIQSGVALFLK 12989
++I +KD IP++ + GL HW +M ++ G L +LR +L E E + ++ A E ++ +A++ + G F + D+ +S+ DI + D Q++ SP+ + FQ + WE +L + E + ++Q +W+YLEPIF +P+E F+ VD ++R IM ++++VL S+ G+ L L++ K LN YLE+KR FP M S +GE VEL Q + TSE VE WL L + M +++ D + + R ++ ++P Q++ + I +T + L K+ ++L N + L L +L+ VH D++ L+++ T++EWL QLR+Y + + + +++ + Y YEY GN+P+LV TPLTD+CY TL H+ LGG P GPAGTGKTE+ K L Q +VFNC +G+D +MG+ F GL G+W CFDEFNR+E VLS V+ Q+ IQ I +K++ + ++ N + IT+NP GY GR +LPDNLK LFR VAM P+ LIAE+ L S GF NAK L K+V + L E L+ Q HYD+G+RA+K VL A NL K K + D L++++++ K D F + D+FP + + +Y A EE K N+ K K+++ YE + R ++VG S +GK+ + +L L N+ G + V F +NPK+I QL G D+ + EW+DGV+ + R+ + W++ DG ID WIES+N+VLDDN+ L + SGE IQ ++ IFE +DLS ASPAT+SR GMI++ K LV SW+ Q ++ L+ SL + + + T+N TV K I ++ A F+ L+ +GG + +SRE F ++ + K E +N++ ++ YF E ++ R + ++ + E +++ ++ + ++I+ P I T +D +Q P + GP G GKS+ +LN+ C+ L + H SA T ++ K+++ V+ P +R +L++ D+N+P +++G + L+Q + + G YD + + L VQ + +M + +RF + + SI+ S D + I+++ + +K+ P+ I + M+EVY + + + SHY F D ++ + L L S +L+ + +E R++ DRLV + R L N+I V+D N + +G + +Q G + E + + L +Y++ ++ +++++F + ++++++ RVL +PGG+ LL G G GR++ + L + M ++ L P++ + Y + ++++DLK L + AGV+G+ V L+ D Q + +LE I+S+L +GEVP L+ +E + I+ +++ +A ++G + +L +F R K LH+++ F + P+ C++ W + W +++ ++ + + E + + KT T ++ L+ + +L + T Y+ I + ++ +K+ I + G+ +++ A+ VA++K + + L + +++ K ++ ++ S+ A R + E +K E + K+ +++LA P ++ A A+ +K SD+S ++A++ PP ++ ++ V ++ GT + W + LG +++ +D I + E +T FDP AS AA L W+ A Y + +AP + + + + +L + + + +V+ + +K FE+ T + A+LE ++++ + AE L+ L E + W+K +L LT L++A + Y+ R+ +LW + F + K L E W GL +D S++N VI++ P +IDP A W+KN KD L ++ D ++ LE ++FG L+++ V + L+P L PLL QG + ++LG+++I+Y+ DF+ ++ TR P P+ VS +NF T GL+ QLL + + +P+LEE +T L+ + K +L ++E+S+L+ L ++ GNIL ++ + K + IT Q ++ + K ++ + E R+ + +A+H S LFF I+DL+ I+ MY++SL F+ L+ I++ +++ L LE L +Y VCRS+F+ D+L+F+ + CC +L +E E L TG + N P W+ D++ AS +P + IK+ + + S E C ++P KL+ QK++I + LRPD + A+++F L K + P + +L + + ++ S P++ ++SPGADP L+ S K + R+ +++GQGQ I ++ QNG W+CL+N HL SW+ LEK + + H+DFRLW+T+ P F +LQ+ +K+T E P G++ NLL+SY D S+ +F + LF L +FHA++QER+ F P GW Y F+ +DL L Q + + ++ + ++ I L +GGRV + +D R+L + + ++ + ++ + SG ++ P +S DY+ I L P F L +N+D S + + L + Q G T +D +I +++L P +R +L + + + S+ L + ++ERYN L + SL +L K LKG ++ E++ ++ L+ G+ P W + +P Y+ + + K ++ W E + + L F FL + Q AR +I +D L F V S + V + L ++G +D G + + R +L + + WV + N D + P+Y R ++ + + WI+ GVA+ L+
Sbjct: 565 EQIQKFKDYIPVVSILCNPGLRGRHWEKMSQI----AGFDLTPNFGTSLRKLLQLKLEPF--LEEFETISVAASKEFSLEKAMQTMTQVWDGVSFHHQPHKDT---GVSIFTALDDIQMMLDDQIVKTQTMMGSPFVKPFQSEMKQWEERLLHIQESIDEWLKLQAQWLYLEPIFSSQDIMQQIPEEGRLFQTVDRNWREIMGHCVKDSKVLQATSLPGLLERLQDSNALLEKIMKGLNAYLEKKRLFFP------------------------------------------------MYSSEGERVELI-QNISTSEANGAVEKWLLQLEDGMISSVRDIIDRS----RAYEKTARNQWVKEWPGQVVLCTSQIFWTLEVHKALG-------LKKYYQQLQNQLNEIVELVRGELPKQTRTTLGALVTIDVHARDVVKDLIEK-VSDETDFEWLAQLRYYWMNDN--VRVHIINCDVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFHLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQVLCIQRAIMHKLEYFDFEGTMLKLNPNCFVSITMNP---GYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNAKPLSAKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLLAAGNL----KLKFPNENEDI------------LLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGVSLPVADYKLFLEAAEECCKIHNVQPTKVFTDKLIQTYEMMIVRH-FMLVGESFAGKTKVLHVLADTLSLMNERGHGEEEKVIFRTLNPKSITMGQLFGQFDLVSHEWTDGVVANTFREFALAETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSNQMSLIFEANDLSQASPATVSRCGMIYMEPSQLGWKPLVISWINTLPDPLQSPDNRSLILDLFHWLIPPSLQMLRRHCREVVPTTNSHTVVALCRLFKMILDEPVKTGPDDESIRTWIMAAFASSLVWSVGGCCDTDSREKFNDFIRQTVSGKNKEHPIPETIERWECPINEKGLVYDYFYEFKEKGRWIHWN-DTIENINLGEINTKGQEIIVPTIDTVRYTYLMDL------CISQGPLLFVGPTGTGKSVYVKDKLLNNLDKDCY--LPFFINFSAHTSANQTQNIIMSKMDK-------RRKGVFGPPLGKRYVLFVDDLNMPAREQFGAQPPVELLRQFLDH-GHYDLKDTSKISLVDVQFIAAMGPPGGGRNAVT-SRFLRHLNIISINPFSDDTMVHIFSSIVAFSMKKNLFSPEFVIVGNQ-----IVTAMMEVYKKAMANLLPTPAKSHYTFNLRDFSRVIQGCLL--LKKGSLEGKQTLIRLFVHEVYRVYHDRLVDDEDRTWLYQ-LMNSI-------VKDHFNVPFDQVFGQLKQGDKLEEKDMQNLLFGDYMNPDLEGDERLYTEVPSIETFAEVVKSCLEEYNQMHKNRMNLVIFY-LLEHLSRISRVLKQPGGNALLVGVGGSGRQSITRLATSMAHMTLFQPEISKNYGMTEWRDDLKQMLLRNAGVKGQKTVFLITDTQIKDEAFLEDIDSVLNTGEVPNLFAVDEKQEIIETIRPIA-QAGKKSVELSPLTLFAFFVARCKENLHVVVAFSPIGKAFRKRLRQFPSLINCCTIDWFQPWPEEALERVANSFLESLEMSENER-QEVITICKTFHTSANQLSDFQAELGR---YNYITPTSYLELIATFQQLISQKRETIMNAKQRYINGLDQLAFAESEVAKMKKELVDLQPKLEQAKIDNTKMMEVIEVESIEVEAKSRVVHVDEEAAAMKANEAQAL----KSECENDLAEALPALEAALTALDTLKQPSDISIVKAMKNPPSGVKLVMAAVCVMKNVKPDRIPDPAGTGKKILDYWGPSKKLLGDMNFLRDLKEYDKDNIPVPVMQTIRNEFMTN--PDFDPSKVANASSAAEGLCKWITAMEVYDKVAKVVAPKKAKLAEAQESLAATKAVLDQKRAELKEVEDRLTALQKTFEEKTEEKARLEMQVESCARKLERAEKLIGGLSGE-KIWSKAADDLQNTYDNLTGDVLISAGVIAYLGPFTSGFRQNCTKLWTTLCQSKNIPSSDDFSLSKTLGNPIEIRAWNIAGLPNDSFSIDNG-VIVRNSRRPLMIDPQGQANKWVKNLEKDNNLNVIKLTDGDYMRTLENCIQFGTPLLLENVGEELDPSLEPLLLKQTFKQG-VESIKLGERVIEYSADFRFYVTTRLKNPHYLPEVATKVSLLNFMITPEGLEDQLLGIVVAK-EPELEEERTALILQSANNKRQLKEIEDSILETLQSSKGNILEDESAIQILDSAKIMSNEITKKQQIQIAEKTELKIAESREGYREVAKHSSILFFSIADLTNIDPMYQYSLIWFVNLY--------INSIQDIKSKVLKQRLEYLKDHFTYNLYCNVCRSLFEKDKLLFSFLL--CC--NLLARKEIEHSDLMFLLTGGIGLQNTVANPD-PSWLQ-DKSWDEICRASELPGFQGLEAFIKNPEDFKLIYDSREPCSIDLPAPWCEKLTDLQKMIIFRCLRPDMV-PAVTKFVTRNLGKKFVQPPAFDLTKSF-LDSNSTIPLVFVLSPGADPMALLKFASDKKMDGSRFQSISLGQGQGPIAAKMIFTAMQNGSWVCLQNCHLAVSWMSNLEKICEDFSLTTCHQDFRLWLTSYPSPKFPVGILQNGVKMTNEQPTGLRLNLLQSYLTDPVSDPNFFNGCPDKKPVWEKLLFGLCFFHALVQERKKFGPLGWNIPYGFNESDLHISMRQLQQFVNEYDK-VPFEAITYLTGECNYGGRVTDDWDRRLLMTTLADFYCEDIIKTFRYPLSPSGKYFA----PPKSSYEDYIQFIENLPISQQPEVFGLHENVDISKDLQQTKLLFDSLLLTQGGGAMGGVSSGGDNTLYDIANNILTQQLPPTFDREAVLLKYPVLYEESMNTVLVQ-----------EMERYN---LCSTICVSLQNLLKALKGLVVMDSELEAVAGNLIVGKVPEKWAKFSYPSLKPLGSYITDFLARLKFLQVWYENGQ-----PKVFWLSGFFFTQAFLTGVMQNFARKYQIPIDLLTFDFEVLPIDKSETPPEDGVYVNGLFLDGARWDKEGVLTEQHPR-----ILFDSMPIIWVKPEKKNMIQTDSLYVCPLYKTSERKGTLSTTGHSTNFVIAMMLSTKKRPQHWIKRGVAMLLQ 3679
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Medaka
Match: dnah5 (dynein axonemal heavy chain 5 [Source:NCBI gene;Acc:101171908]) HSP 1 Score: 934.48 bits (2414), Expect = 0.000e+0 Identity = 762/2763 (27.58%), Postives = 1328/2763 (48.06%), Query Frame = 3
Query: 5061 TPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLER-RVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLK--GAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYN------GLSNLKA-IKNKAHFSVCLIKGL----GGNLNENSRETFALW-----VYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPL---ILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKL-KSVQV-TTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFY--DSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYT-----------AYLKPVLKRLIPK-----HPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVS-LLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVE---VQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKL-----TSEYLKDTIDRGLLQYSRECRD--LDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSL-----KDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAK--PKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIM-------------GTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMK----DLEKGVSDVDKAVAG---YRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEK--------FDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVAIS--NLASAMPELWSVLNIKD-----DDLWHQ-FAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWL-PVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIK--KSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQ--RFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVA---FLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQ-WEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIK-ISMDELKF---VCRWGGSNV--SAKYSVKIGNLHIEGCLFD--GTMITECNRDSNSIVLLPPVSVGWV-DKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPC-------QSGQQDKWIQSGVALF 12983
T L CY+TL Q + M +GG P GPAGTGKTE++K +G G+ V+VFNC + +D + +GRIF GL + GSWGCFDEFNR+E VLS + QI I+ K++ + + V+++ IF+T+NP GY GRQ+LP+NLK FR V+M PD +I V L S GF + +L K ++ L E L+ Q HYD+GLR + +VL+ GAA + SD E+ ++ + L+ LSKL D F SLI+D+FP I++ + Y L +AI++ I+E +++ K++++YE R R G++ +GPSGSGK+T ++L A+ + GQ + MNPKAI Q+ G +D+ T +W+DG+ + R+ +K + WI+ DG +D WIE+LNSVLDDNR LT+ +G+RI PN +FE H++ ASPAT+SR GM+F+SS ++ WLK++ ++ +L F + + + EF + + GL LK +K H I L G L R+ LW V + + P ++ + +YY + V +S EE + + TP IL ++ F I S + +L G +G K++++ K +Q+ L+ S+ TTP+ + Q+ ++ ++ G Y P +++ + + DIN+P +++WG ++Q++ KGFY + EF + VQ + +M R + + + PS ++ I+ +++ V +R IP+ +W Q +K+K+L +KF HY+F DL++ +L + +S N LL + +E R+ DR D + D L + + E V D + +FV + P+A G P + K+ + E LKD ++ L QY+ R +D++ F++ ++ K+ R++ PGG+ LL G G G+++ + L S + K+ + R L+ LKS + AG +G+ I + D++ E +LE +N++L+SGEV L+ E++ IL L ++ +L +YF R++H LH++L F PA C++ W +W +D+++++ + ++ + Q+ + Q ++ YFL + V T + Y++FI+ Y IY++K+ E++ N + G++K+ EA E VA L + + K L +AD LK++T + + K E++K+ K + KA +++L P +++A A+ IK SD++ +R L PP +I ++ VLL++ + +SW N + E++ F I E+ ++ +++ + A+ AS A L +W KA + +++ P LK NL E ++ DLEK +++D A R ++E+ + L + K + A +L+ L E ERW +Q E A+ L LLA A + Y S P +Q + L + L++ D+ + L EW +GL +DELS+ N +++ + P LIDP + W+KN +L+I + F LE S+ G+ L+I++V + L+PVL +L + I G V++GDK +D FKL++ T+ P P P+ A S ++FT T GL+ QLL + K ++E+ +T+LL++ K ++ ++E++LL L + G++++++ L++ L TK+++ ++Q L+ + Q+ ++ R+ + P+A GS L+F+I+++S +N MY+ SLT FL LF +L S S++++ R S+I + VY Y R +++ + +F L ++ E T I + ++ A+ + +S NL + +LW I D + LW F K + E +P S ++ L F+++L+I+ PDR + ++ D + K+ +++ +E E+ P++ +S G+DP+ + L K+ RY V+MGQGQ LL + NG W L+N HL +++ +++ + + + FRLW+T E H F LLQ S+K T E P G+K L R+Y ++D + + + L+ +A+ H+ +QERR F P GW YEF+ AD A + + + + + + W + + +GGRV + +D R+L+++ K +FN ++ NFY +P +S YLA I L Y++P F L N D + Q + V+ + +Q S G + + SR + +L + + +P +KR P+ FL+ E +++ V S+LI L + G+ ++++ +++ +C+ + P W+++ W F + L+ + + + W + T F+P FL A++Q AR K ++D + V +W ++ V + L++EG +D +TE S VL + V W+ +N +S + ++ P Y K T+ DI C + + W+ GVAL
Sbjct: 13 TYLMTWCYITLAQALGMCMGGAPAGPAGTGKTETIKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIAIVLTCKKDRHKTFVFTDGDSVDMNPEFGIFLTMNP---GYAGRQELPENLKINFRSVSMMVPDRQIIIRVKLASCGFIDNVKLACKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAA------------------KRANPSDTESTIVKRVLKDMNLSKLIDEDEELFLSLIEDLFPGIELNKEGYPELEAAIDKKIQETGLINHPPWKLKVIQMYETQRVRHGMMALGPSGSGKTTCIQILMKAMTECGQPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLKAKKGEHIWIVLDGPVDAIWIENLNSVLDDNRTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMSSSVLGWSPILEGWLKQRSPNEAEVLRQLFSSSFSELYRFSVQSLEFKMDMLEAFVIMQCINMLQGLIPLKVRLKLNQHLERLYIFALMWSAGALLELEDRKKMELWFRGNDVIRRSLPEIPPGREETMFDYYVT-AEGHWVHWSTRVEEYIYPPDV-------TPKYSSILVPNVDNVRTDFLIDTISKQGKAVLLIGEQGTAKTVIMKSFMSKYDPEIQLGKCLNFSSATTPL-MFQRTVES--YVDKRMGTTYGPPAGKKMSILIDDINMPVVNEWGDQVTNEIVRQLMEQKGFYNLEKPGEFTNIVDVQFLAAMIHPGGGRNDIPQ-RLKRQFSIFNCTLPSNASIDKIFGVIGEGHFCAQRGFIEEV-QRTIPQLVLLTRRLW-QLTKIKMLPTP---------AKF------HYIFNLRDLSRIWQGMLCTNH--SSRNIIFQVLLALWKHECKRVIADRFTMPDDVEWFDQTLAKLVEQQLGEEHKKVVDCGVERYFVDFLRDPPEATGEEPEESDFDMPKVYEPIESFESLKDRLNMFLCQYNDSIRGNGMDMVFFQDAMIHLIKVSRIIRTPGGNALLVGVGGSGKQSLTRLASFIAGYKIFQITLTRSGLLEGLIAYLKSLYRIAGHQGKGISFIYTDNEIKEESFLEYMNNVLSSGEVSNLFARNEMDEILSDLVPVMKREFPRRPPTNENLYDYFMSRVRHNLHVVLCFSPVGEKFRNRALKFPALISGCTMDWFSRWPKDALVEVSHHFLSAFDIDCSPQVKSEVVQCMGSFQDCVAEKCVDYFLRYRRSTHV---TPKSYLSFIQGYKTIYVEKRAEVQMLANRMNTGLQKLKEASESVAALSKELEVKEKELQIANEKADMVLKEVTVKAEASELVKVEVQKVKDKAQAIVDSITADKAIAEEKLEAARPALEEAEAALQTIKPSDIATVRTLSRPPPLIMQTMDCVLLLLRRRVNPVEINAETNFITSSWQESLNLMTSGSFLSELKQFPKDTINEETVELLQPYFNL--PNYNIERARTASSNVAGLLSWTKAMASFFAINKEVLP-------LKANLAVQENRLAVANLDLEKAQAELDAKQAELNVVRAEYEEAMTEKLTLLEDAKRCRRKMQIASNLISGLAGEKERWTEQSKEFAAQTKRLVGDVLLATAFLSY--SGPFNQEFRSLLLNEWQCELKQRSIPFGNNLDITELLIDASTVSEWNLQGLPNDELSIHNGIIVTKAARFPLLIDPQTQGKTWIKNKEAKNELQITSLNHKYFRNHLEESLSLGRPLLIEDVGEELDPVLDNVLEKNFIKTGSTYKVKIGDKEVDVMKGFKLYMTTKLPNPAYTPEISARTSIIDFTVTIRGLEDQLLGRVILTEKREMEKERTDLLEDVTYNKRKMKELEDNLLYRLTSTQGSLVDDESLIVVLGNTKQTAEEVNQKLQIAGDTQIQINAAREEYRPVATRGSILYFLITEMSMVNVMYQTSLTQFLGLFDLSLARSSKSSNTSERIKSIIEYMTFKVYYYAARGLYEEHKFLFTLLLTLKIDMQGKNVTHKEFL--TLIKGGASLDLKTCPQKPAEWILDMSWLNLVE-LSKLWQFSEILDQVHHHEKLWKSWFDKEAPEEEVLPNSYQS-LDCFRRLLLIRCWCPDRTIAQARKYIRDAMGEKYTEGVILDVEGTWE-ESNPRTPLICFLSMGSDPTDSIIALGKKLKIETRY--VSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLNFMDELMDTVIETECINDSFRLWITTEVHKNFPITLLQMSIKFTNEPPQGLKAGLKRTYGGINQDLLDVSNTNQWKPMLYCVAFLHSTVQERRKFGPLGWNIPYEFNQADFNATVQFIQNHLDDMDTKQLVSWNTVQYMIGEIQYGGRVTDDYDKRLLNTFSKVWFNKNMFERDFNFYKGYGIPKCSSVDQYLAYIQGLPAYDTPEVFGLHPNADITFQSKQAKDVLDTILSIQPKDSSSGGGETREAAVSRMADDMLEK---------LPPDYIPFEVKRLQKMGPLKPMNIFLRQEIDRMQRVIMLVRSTLIDLKLAIDGTIIMSENLRDALDCMYDARIPARWMKESWASSTLGFWFTE-LLERNRQFQTWLFKGRPNCFWMT-----GFFNPQGFLTAMKQEIARANKGWALDRMVLCNEVTKWMKDDIPHPPAKGVYVYGLYLEGASWDRNNCRLTE----SKPKVLFEMMPVIWMYAENNGSSEKKKKIVKDPRLYSCPIYKKPTRTDINCIASVGLKTTQPPEHWVLRGVALL 2683
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Medaka
Match: si:dkeyp-86b9.1 (dynein axonemal heavy chain 10 [Source:NCBI gene;Acc:101170214]) HSP 1 Score: 930.628 bits (2404), Expect = 0.000e+0 Identity = 826/3200 (25.81%), Postives = 1481/3200 (46.28%), Query Frame = 3
Query: 3681 QDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGK----NALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDI--QHII-TMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTT---LSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELL---NENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYN---GLSNLKAIKN------KAHFSVCLIKGLGGNLNENSRETFALWVYELT------DEKTPEMNKQ-----NVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKI-WLNSDT---QQPFILSGPEGCGKSLMLNHCFQKLK--SVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYD--SNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVD-----DYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLND-VWFVTW-GSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINK--IPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFEL-----KNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRK----EKMQLWMEKTGL---EKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQ-QDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGN-IXXXXXXXXXXXXXXESSITISQ-SLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMS-HCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVL--NIKDDDL-WHQFAKSSECERE-IPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSL-KPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRN----IQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYG------KIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPE---EPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGT---MITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDK-----IVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
+DHW ++ + L+ TL + + E+ ++A I E+ A E++I E+ F + + + L+ +I+ + ++ LQ + S + F D WE L E ++ Q+Q KW+ LE IF + LP+E + +++ + F IM + C++ G + L + + L+R QK L +L+ KR+ FPRF+ I DD+LL +LG S +P I+ H+ K++ I + D Q ++ M S +GEV+E R V + + VE+W+ + EMK T ++ + Y D S Q + A++ + +T E + N+ + LKK ++++ + ++ T LK+ ++++ VH DI+D + ++ + V ++EW QLRFY + ++ + +Y YEY G +L TPLT + YLTLTQ + M LGG GPAG GKTE+VK L G +V +C E +D ++G+I GL KCG WGCFDEFNR+ +VLS VS QIQ I++ + + + +++++D + I+IT+NP+ Y R +LP+++K FRPV + PD I E++L S GF AKEL +K+ ++ + L+ Q HYD+GL + K+VLK A KMK D++E +D ++++ALR L KL D F LI D+FP +D + + + +EE++++ N L Q K++++YE + + +IVG + GKS + L A +G K Y +NPKA +L G D +TR+W+DG+ + R++ + + + +I+ DGD+D +W+E++NSVLDDN+LLT+ +G+RI+ + +FE DL ASPAT+SR ++F+ + W+K + L+ + + +D + +E + ++V V L L KN + +F L LG L E+ R F V L+ DEK + + +++F+E Q + V +S E I P + ADI +D + W+ ++P +L G G K+ ++ + + S T++ S++TT + + + L I T Y P ++L+++ DIN+PK+D +GT Q ++ L+ ++ G YD L F + + + +M + RF S+ + +I P+ + L+ IY + +K + + ++ + T+ E +L + D HY F+ +L++ + L P S T + + E +R F DRL + G + + + + + L D + F + +RE ++ + + + + Q LF++ +++ ++ R+L G LL G G + + L + + ++ + RGY F+NDLK+ G+E V L D +E +LE IN++L S VP L+ +E E I+ + A + G + S+ YF + + LHI+L + + C++ P + W WS ++ + ++ IP+ + + L + + L H C ++TS+ +++FI Y + L++KNE + ++ + ++ EA+E + E L +K ++ V+LAK+ A + ++ D ++ + PP ++ + E +L++ G + +W++ + + + G + D I+ S I + L + S + + S A + + +V++ + Y +++ P +++ +L++ ++ +++ ++ ++++ K + ++ +E A LE EL K ++AA+ LV L +E E W K + EL + L L+AAA + Y + D R +K +++ G+ + F + FLT + E + W EGL DE S++N ++ +G P IDP A W+KN KD L+ V+ D +F LELS+++G ++Q+V + ++P++ +L +++ R V+ LGDK ++Y+P+FKLFL T PQ P +N++T + GL+ QLL++T ++ +++ L++E + K L + +SLL EL +TGN + N + + E+S TI + S+ +S ++ + R+ + P+A+ G+ LFF +SD++ +N MY++SLTS+L LF+ +L S + R ++I L V+ Y +F +L+F+++M+ + + PQ+ F +S + +WI I+ LA PE +S L +I+ + W + E+ P LS FQK+L+++ LR DRL A++ + V + P +N IYE T + PI+ I+S G+DP+ DL + + K ++ +A+GQGQ + L LL K G WL L+N HL+ WL LEK L + P+ +FR+W+T F +LQ S K+ E P +K N+ +Y S+ +S + ++ LA+FHA++QER + GW+ F+ +D A E+L + K + I W+ + L ++GGR + FD R+L Y+ YF D + + +F+ ++P K Y I ++ +P LP ++ ++ LR+LQ + G D + + + +N++ L L +S VV +L R+N KLV + S++ L + L G ++KE +L+ P +W + PE D+M L + + W ++ E + ++ L L P+++L A+ Q R +D+ F ++ ++ G +G M C S VL+ + + V Q NS + + P+Y LR +V + D+ + W+ SGV L+L S
Sbjct: 1176 RDHWNKLMERTGKSFDMNLQRFTLETLF--SLELHKYANDIDEIVTSALKELSI-------EMTWKRTKFNMQPQLKVNQERVFLLGAVDNILVNLDNDVMKLQCMAGSRFGGPFLDAIQQWEKNLTLFSETIEIWLQVQHKWMNLENIFCGEDICSQLPEEAKKLKKITKKFTEIMKSTENEPNIKKCCTVPGRLSSLWVLRNDLERIQKNLANHLDSKRNEFPRFFLISDDELLNVLG-SVDPACIQEHVIKMYDNIESLRLGVDSSGQTVVGAMVSNEGEVMEFRKPVPLEARVEDWIMAVLQEMKRTSRLITKEAVYHYVDWIRSYQCMMVLAANR-----------VWWTWEVENAIKNVNKGDKYALKK-YAEQIHRQIDELVTCLGRPTKESDRLKISNVLVTDVHARDIVDNFVGRSIKEVHDFEWESQLRFYWVKEHDSLFVRQCNTSLSYGYEYMGLNGRLAITPLTSRIYLTLTQALSMYLGGALAGPAGAGKTETVKDLAKALGLFCVVTHCTEDMDTITLGKIISGLAKCGFWGCFDEFNRIGASVLSVVSSQIQAIRNALTSHFKMFQFEGQQISLDDHMGIYITMNPS---YERRPELPESVKVFFRPVVVVTPDVQQICEIMLFSQGFLQAKELAKKMTVLYKTAGIQLSKQPHYDFGLHSQKSVLKMAG--------KMK---RDSLELSEDV-----VLMRALRDINLPKLVSEDVPVFLGLISDIFPGLDSSRVGFPSFRETVEEILQKSNYTILPDQVDKVVQIYEIMLTQQATMIVGQTCGGKSVVINTLCQA-QTLGLCTKLYPLNPKATSVDELYGSFDPETRDWTDGIFSKLFREINQSTDKKERYILFDGDVDSQWLENMNSVLDDNKLLTLANGDRIRLQSHCALLFEVGDLQHASPATVSRCAVVFIDPKHLSYTPYWQRWMKNR-------LNRLFEKYVPSCID-VTLNSETIVPRTDVNMVSQLCLMLDVLLESKNSSAEVLECYFLEALYCSLGATLVESGRLKFDKLVKSLSCLSTVDDEKAAAGPGEIPYLPTLYDFHFDETQEKWVPWSSLVPE-----------YIHNPAMKFADILPTVDTTRTHWILEQMVKIKRPVLLVGECGTSKTAIIQNLLKNTSTDSSISLTINFSSKTTSLDLQRNLEAN---IEKRTKDTYGPPIGKKLLVFFDDINMPKVDDFGTQQPVALLRLLLDQGGLYDRKQKLSFKTIKDLGYIAAMRKTGGGRNEVD-PRFLSLFSVFNIPPPATESLHLIYASIIKGHTRPF---------KAAIQEVCQTITECTLKLFTTIITDLPPTPSKFHYTFSQRELSR-IYCGLTLTKPDFSCLTVEQFVRVWRNECLRNFHDRLTDETDKALVHGHIKKLVEEYFETDSEAVLADPILFGDYRAAREECEQ------------RVYEDIGDYDVSKAIFQ-----------LFEDAVEHLTRVHRILRSDRGHALLIGADGSWTQALTKLAAFTADCEVFEIILRRGYNELNFRNDLKTLYLKLGIENRRTVFLFTDAHIVEEGFLEQINNMLISM-VPTLFADDEKESIIKQINSEALQEGAGSSKESVWQYFLRKSANNLHIVLCLSATGDALKTRCRNFP-LMSNTVIDWYLPWSAQALHAVAQCVLENPTIPKAHFGAVIDHICMVHASLC---DFSKQLLLKHQRC--NYATSKSFLDFISSYSTL-LEEKNEHVLQCKCLEGSLNRLREAREQIDE------------------------------------------LNLKLADQKVVLAKKTAT-----------------CTAFLEEIDKNQTISFAKPPKQVQVVCECILVLRGKKELNWLTAKKMMSEAGFLHSLMQMDCDSISN-SHISTIKFLKNLQTSVE--EMQSISKAGSGILKFVESFMSYWDIAKEVQPKKDQVKRLEKEFLQSKAELECIKNDLNNMQKEASSLKEKYED-----ANLEKELQLDEAKLMERRLTAADKLVLGLTSERE-WTKDLEELKQQHECLLGDCLIAAAFLSYAGAFNWDFRNNMVYDKWTQDVKQKGIPLSQPFKIENFLTNQLE-ISWGSEGLPPDEQSVQNGILTTKGSRFPLCIDPQQQALNWIKNKEKDNNLKQVSSLNDPDFLKQLELSIKYGYPFLLQDVNEDIDPIIINVLERNVVVSEGRTVIVLGDKEVNYDPNFKLFLHTTLANPQYSPSVFEKALVINYSTLR-GLEDQLLSVTTGFLEKVFQQQHLLLVEEISENKTLLKSLGDSLLMELGTSTGNMLDNTELIQTLEKTKTEASETIKKLSVAQSKTVEFA--NLREGYRPVAKRGAVLFFALSDMALVNRMYQYSLTSYLSLFELSLQESLAHPNLQQRLENIINTLTYNVHNY----LFGKHKLLFSMNMTVKIEQTEGGVPQKELDFLIKNLSGDGTKVQKPHEWIPDQAWQDITKLAELFPEQFSSLPSDIEQNSTNWKSWWDLRAPEQAPFPLQYSESLSAFQKLLLLRCLRADRLHRAMADYVT-VTMGNCVHPPLINFTTIYERST-AFSPIVFIMSSGSDPTTDLIKFAEK--SGTKFTLIAVGQGQEQVVLKLLEKAVSIGSWLILQNCHLLVKWLKDLEKALEKITNPNINFRMWITTNAIDDFPIGILQKSQKVVAEPPEDIKLNMKATYSKISQQTLSSCQHPAFCSLVYVLAFFHAVVQERSKYGKTGWSVPCNFNDSDFSASLEVLSTYLTKCHEQGDSFIPWESLQYLIGEVVYGGRAIDSFDRRILKVYMDEYFGDFLFSPFQHFHFFRNKDVGYKIPPPGRKHVYTE-IEKMPLITTPEVAGLPSTVEIGYYTQAVEEMWTHLRVLQPETQVGRGIGGDEHISHIAQDIQKQLPELFDINLVGEELGTDLSPTS----VVLLQELRRFN--KLVLCMQQSVVELLRALTGEVGMSKESDDLAHAFCNDLVPAMWKRL--APETLKSLDDWMSHLRRRYEQYSNW-QVREGE---PKVMWLSGLHVPESYLAAVVQAACRKKGWPLDQSTFHTEVTRYRTEDDIDDRLKQCYLSGLFLEGADWDMENGCLARSKPKVLVVELPILKVIPVQKNSLRLRNTLRTPVYTTSLRRNASGAGLVFEADL-FTTMHTSHWVLSGVCLYLNS 4175
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Planmine SMEST
Match: SMESG000008382.1 (SMESG000008382.1) HSP 1 Score: 6964.39 bits (18068), Expect = 0.000e+0 Identity = 3504/3509 (99.86%), Postives = 3506/3509 (99.91%), Query Frame = 3
Query: 2466 MKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFISDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
MKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFELMMESFQMMMQEQIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQKIKDKKLELEELVIIKTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQ NDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCSMNSSSSMGRSSLSTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREPQAAGAPPPIQGKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNLLQEEEKLKIELSKMEESLLQELANATGNILNNKDLLLSLNKTKESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFI DKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQEL+TKVIGSERYNQVAMGQGQADI LNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDRSSQRIISSQVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSE+DMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS
Sbjct: 1 MKKFITLPNQFKGLNDSSPGNQLIFPSVIERNAAGFVVCYQKAEFLFQRLSACLNKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKAMKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTVSQLQQKWDKFELMMESFQMMMQEQIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQKIKDKKLELEELVIIKTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTIRLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMSNQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFIVHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQENDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQDEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNGLSNLKAIKNKAHFSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCSMNSSSSMGRSSLSTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREPQAAGAPPPIQGKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESGHRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGSDNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEKFDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNLLQEEEKLKIELSKMEESLLQELANATGNILNNKDLLLSLNKTKESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCRPDLFKPQEWELFTGTFIGDKSDRNITVPKWIDADRTVAISNLASAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELATKVIGSERYNQVAMGQGQADIALNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDRSSQRIISSQVILQLRILQRFSVHGTKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSVGWVDKNQPNSYSENDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 3509
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Planmine SMEST
Match: SMESG000008384.1 (SMESG000008384.1) HSP 1 Score: 1399.8 bits (3622), Expect = 0.000e+0 Identity = 687/691 (99.42%), Postives = 689/691 (99.71%), Query Frame = 3
Query: 96 MSKIEDQRKDTIFLITKSHFPNQNSKFVNEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDTDPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLICEKI 2168
MSKIEDQRKDTIFLITKSHFPNQNSKFVNEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDTDPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFL +K+
Sbjct: 1 MSKIEDQRKDTIFLITKSHFPNQNSKFVNEECLDKFFDNLDNNVLVVKFIDNKFIFSNQLNTTDKVVNALVFIKTSPSIITPDNINSGIIVTTLSENPISSLYNIIQNIYGPILLSDTDPKIQKLISELENGLGSIIRKPLSKKSKYQTDETIVLGIFSIDDEIMFWNDSLSASSHDQNQSRINELISFLQQVNEEMKLIASESLNESFSYLENVFGLLNDIWQSETINPNYPQSRMKTLMEIIANELVRIIQTQLNPLWFWEDSYALVKESLTQAIEVCSHWIDMCDKLIKRYWKQYLPHKWNTDNNLNLSYISNFQIRLTEISSLRTVHEQITQILPHRERQEFKIEEAFKYFLNILPLAYNPYTEPIWKIAVKKFHRHIEPAETNIGTRLKVIFKECASAEMPQQLLRLFQRYNDLITRPKISVNLLQERETLLAQLVIHRKQLREDFIHRSRQGKVPPTKNASDEISKIVWSKQLEAKLNEILSITSNVLKDLDGFEKFLKETKNFLEEISNWRQEQFEQWNQEMTRRLDDSSNDGIRLDMQGRLMELSQKDGLLYVNYSDRLVNLIREVRTLSGLGYDISKSVIAAADNGQKFYSKAVILKQVAQFYNTINTQMIPCQQAMMLDAAINFEKLVKSVGSQSKTKNVVQWNNPEELNQFIDKLQKASHSIISQNRLLRKQHFLSVKKL 691
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Planmine SMEST
Match: SMESG000038602.1 (SMESG000038602.1) HSP 1 Score: 1346.26 bits (3483), Expect = 0.000e+0 Identity = 957/3418 (28.00%), Postives = 1730/3418 (50.61%), Query Frame = 3
Query: 3453 MWSQFEEYQTGLQNLAKEDWLSFRSRYYLFE-EFLTQWFEKLRNAEITTMTI-RLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIREL-ELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSE--VENWLGNLNNEMKTTLSDQLSYALQDLR-MSNQSN-----YGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFI----VHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCV----IQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGI------KNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANL----LEMHKSKMKTQGNDTIEN-VQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQH-------KKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKI-GQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQV---VKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKK-------QDEHD------------------------QHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVG--TVYNGLSNL-----KAIKNKAHFS----------------------VCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNK-QNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESER-LILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYD-SNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGIL-------FNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAK-------PKTQLTGSDNLNSYFLDLHDTCP------------VEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWM----EKTGLEKFDMRK--FLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRAL-NTSEIST--DSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHC----CRPDLFKPQEWELF----TGTFISDKSDRNITVPKWIDADRTVAISNLA----------------------------SAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVL--ELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTK--------VIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSN--------RNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVN------GSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRILQR-------FSVHGTKFDKDI--------WSRELNPVLNRW-KILNQGLNIIKASLPDSLKRSSTDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGP--------EEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKFVCRWGGSNVSAKYSVKIGNLHIEGCLFDGTMITECNRDSNSIVLLPPVSV---GW--VDKNQP-NSYSEDDMISLPIYYDILRDKIVTKIDIPCQSGQQDKWIQSGVALFLKS 12992
+W++ + ++++ + WLS + R + E LT ++L N+ + ++ + MY + + ++ E + + HW + R LN+ +L L L + D +++++ E I+E+ AQGE + E +R++ E+W V +L Y Q+ S +IK W D+ ++V ++ + S+K SPY++ F+++A WE++L ++ +QR+W+YL+ IF +A LP E RF+ V +F +M V ++ V + +++ ++ L + D L + QK+L EYLE +RS FPRFYF+GD+DLLEI+G S + + ++ H KK+F G++ + ++D + I+ M S +GE + + V I + +WL + EM+ +L+ L+ A++++ +SN + + DKY +QI+ L+ I ++ E L ++L+ + ++ +++ AD+ V KL+ LI++ VH D++ L + S ++W+ Q+RFY K + I + +A+F+Y +EY G +LV TPLTD+CYLT+TQ + LGG+P+GPAGTGKTESVK+LG+ GR VLVFNCDE D ++MGRIF+GL + G+WGCFDEFNRLEE +LSAVS QIQ IQ+ + K + LL ++V+V+ + AIFIT+NP GY GR LPDNLK+LFR +AM++PD LIA+V+L S GF+ A+ L K+V F L E L+PQ HYD+GLRALK+VL A N+ ++ K K+ +G + E + + E ++++Q++ + KL D SL+ DVFP ++ ++ E L + +V + + +V + +K+L++Y+ G+++VGPSGSGK+ ++L AL I G ++++PK+I + L G++D +TREW+DG+ T+ R++ V+ + WI+ DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV +FE DL A+ AT+SR GM++ S E ++T +L + + E D Q +S+ L FF + IAK +++ + ++ T L++L ++I+N ++ ++ + G+ RE + ++ ++ P + +N++++ N Q V +S + + ++ ++ P T D R+ WL +P +L GP G GK++ L + L ++V L+ S+ TTP +L+ +Q C + G V P++ + LI + +INLP +DK+GT ++ISFL+Q++ + GFY +++++V + +Q V + N + GR LS RF V + + YP + L IY+ + + +L R++P S L N M+E + + + +FT D HY+++P ++T+WV + P+ S + L+ I ++E++R+FQDRLV D R D + F I+ E +++ + + W S K +T E L+D + L + E D+ ++LF +V D+V ++DRV +P G +LL G SG G+ T S VS ++ + + K+H Y + F DL++ L+ +G +GE I ++++ ++ +LE +N+LLA+GEVPGL+ +EL ++ K+ A G + L +F +I LH++ M+ S ++PA F C + W WS ++ ++ N++ E ++ P+ + +N+ +H T T RHY++ I Y+++ +K+ ++E +Q H+ G+KKI + + V ++ ++ + L A+ LK++ Q A ++K + L + ++ + +++ + EL +EP V +A+ AV +I+ D+ EI+A++ PP+ ++ +E + L++G T W S+ + K I F+ ++ +R +++ D ++ + +AS A P+ WV A + Y+ L+++ PL NE +L E KK ++ E ++ ++K++A Y +++ + A ++ +L + + + L+ L +E RW+ A+++ + LL++A + Y + R W E L + D+ + +L+ ++L W+ L +D+L +ENA+++ + P +IDPS AT +L N +K++K+ + D +F LE ++RFG L++Q+V+ +P+L P+L ++ G R ++ LGD+ ID +P F +FL+TR+P + PD + V+ VNFT T++ L+ Q L ++ +P +++++++LL+ + + +++L +E+ LLQ L A GN+L N ++ L K + +++ +EE+ + ++ ++PLA+ S+++F + +++I+ +Y++SL L +F L N E++ ++ R + L ++ Y + R + D++ FA ++ P F E++ F T S S++ + + D+ ++ L S +PELW N +D+ + AK +LIIQA+RPDRL ++ +F VL +++L I E E + PIL+ G DPS +++L+++ IGS A G QA+ +N ++ G W+ LKN+HL TSWL LEK+++SL+ H +FRL++T E LL++ + +E PPG+K NLLR+ + + +SK R+ F LAW +AI+QER ++P G++K YEF +D + + +D + + I W + L + I+GG++DN FD R+L+S++ F + + + I P + D L +++L D +PS+ LP++ ++ + +I + +Q+ V +K + I W R+L W +IL + + ++ ++ + P+ + E + L+ V L +++V KG++ T +++ L G P +W++ P ++ D ++ L+ + K ++ L S + LG LF + ++ A RQ A+ K +++EL G V + V I G G+ I + S ++ + + W V+K+Q S D + LPIY + R ++ + D + + GVA+ S
Sbjct: 763 VWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNV--SWSLNELQLGKVWDI--DLVKNEEIIREVLAIAQGEKALEEYLRQITEVW-KNYVLELTNY---QSKS-KIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKDLKKLQKHFKKMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASG--VSLESTMT-----VVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNP---GYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTED-GLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVN-IQGTWVAWSNKVPQIEVETHKITATDVVVP---TMDTVRHEALLYTWLAE--HRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAML-RMLP-----SLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVE-GLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALK-----RPILYSNWLS--------------KDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVF-VHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPD-YNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELANVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKG-----------------MYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGS------AEGFSQAEKAIN---SAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPV-ERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTI------ENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIA----LRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCV------ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYD-FYKRGVAILSSS 4082
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Planmine SMEST
Match: SMESG000038602.1 (SMESG000038602.1) HSP 1 Score: 1327.38 bits (3434), Expect = 0.000e+0 Identity = 935/3330 (28.08%), Postives = 1689/3330 (50.72%), Query Frame = 3
Query: 3453 MWSQFEEYQTGLQNLAKEDWLSFRSRYYLFE-EFLTQWFEKLRNAEITTMTI-RLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIREL-ELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIFGKNA-----LPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHIITMKSLDGEVVELRNQVLITSE--VENWLGNLNNEMKTTLSDQLSYALQDLR-MSNQSN-----YGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKELVKKLNIYTNAKMSLSADSTFI----VHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCV----IQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQIQIIQDGI------KNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANL----LEMHKSKMKTQGNDTIEN-VQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQH-------KKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKI-GQTVKFYVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQV---VKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKK-------QDEHD------------------------QHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVG--TVYNGLSNL-----KAIKNKAHFS----------------------VCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNK-QNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKSVQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESER-LILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYD-SNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPKHPIWSQNSKVKLLANTMIEVYSQLKSKFTVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGIL-------FNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDRGLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG----HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAK-------PKTQLTGSDNLNSYFLDLHDTCP------------VEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIEPQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWM----EKTGLEKFDMRK--FLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEVDGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRAL-NTSEIST--DSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHC----CRPDLFKPQEWELF----TGTFISDKSDRNITVPKWIDADRTVAISNLA----------------------------SAMPELWSVLNIKDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVL--ELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTK--------VIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEKELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANALFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSN--------RNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVN------GSGNFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXV---ILQLRILQRFSVHGTKFDKD--------------------------------------IWSRELNPVLNRWKILNQGLNIIKASLPDSLKRS--STDSPVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGP--------EEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDEL 12665
+W++ + ++++ + WLS + R + E LT ++L N+ + ++ + MY + + ++ E + + HW + R LN+ +L L L + D +++++ E I+E+ AQGE + E +R++ E+W V +L Y Q+ S +IK W D+ ++V ++ + S+K SPY++ F+++A WE++L ++ +QR+W+YL+ IF +A LP E RF+ V +F +M V ++ V + +++ ++ L + D L + QK+L EYLE +RS FPRFYF+GD+DLLEI+G S + + ++ H KK+F G++ + ++D + I+ M S +GE + + V I + +WL + EM+ +L+ L+ A++++ +SN + + DKY +QI+ L+ I ++ E L ++L+ + ++ +++ AD+ V KL+ LI++ VH D++ L + S ++W+ Q+RFY K + I + +A+F+Y +EY G +LV TPLTD+CYLT+TQ + LGG+P+GPAGTGKTESVK+LG+ GR VLVFNCDE D ++MGRIF+GL + G+WGCFDEFNRLEE +LSAVS QIQ IQ+ + K + LL ++V+V+ + AIFIT+NP GY GR LPDNLK+LFR +AM++PD LIA+V+L S GF+ A+ L K+V F L E L+PQ HYD+GLRALK+VL A N+ ++ K K+ +G + E + + E ++++Q++ + KL D SL+ DVFP ++ ++ E L + +V + + +V + +K+L++Y+ G+++VGPSGSGK+ ++L AL I G ++++PK+I + L G++D +TREW+DG+ T+ R++ V+ + WI+ DGD+DPEW+E+LNSVLDDN+LLT+P+GER+ PNV +FE DL A+ AT+SR GM++ S E ++T +L + + E D Q +S+ L FF + IAK +++ + ++ T L++L ++I+N ++ ++ + G+ RE + ++ ++ P + +N++++ N Q V +S + + ++ ++ P T D R+ WL +P +L GP G GK++ L + L ++V L+ S+ TTP +L+ +Q C + G V P++ + LI + +INLP +DK+GT ++ISFL+Q++ + GFY +++++V + +Q V + N + GR LS RF V + + YP + L IY+ + + +L R++P S L N M+E + + + +FT D HY+++P ++T+WV + P+ S + L+ I ++E++R+FQDRLV D R D + F I+ E +++ + + W S K +T E L+D + L + E D+ ++LF +V D+V ++DRV +P G +LL G SG G+ T S VS ++ + + K+H Y + F DL++ L+ +G +GE I ++++ ++ +LE +N+LLA+GEVPGL+ +EL ++ K+ A G + L +F +I LH++ M+ S ++PA F C + W WS ++ ++ N++ E ++ P+ + +N+ +H T T RHY++ I Y+++ +K+ ++E +Q H+ G+KKI + + V ++ ++ + L A+ LK++ Q A ++K + L + ++ + +++ + EL +EP V +A+ AV +I+ D+ EI+A++ PP+ ++ +E + L++G T W S+ + K I F+ ++ +R +++ D ++ + +AS A P+ WV A + Y+ L+++ PL NE +L E KK ++ E ++ ++K++A Y +++ + A ++ +L + + + L+ L +E RW+ A+++ + LL++A + Y + R W E L + D+ + +L+ ++L W+ L +D+L +ENA+++ + P +IDPS AT +L N +K++K+ + D +F LE ++RFG L++Q+V+ +P+L P+L ++ G R ++ LGD+ ID +P F +FL+TR+P + PD + V+ VNFT T++ L+ Q L ++ +P +++++++LL+ + + +++L +E+ LLQ L A GN+L N ++ L K + +++ +EE+ + ++ ++PLA+ S+++F + +++I+ +Y++SL L +F L N E++ ++ R + L ++ Y + R + D++ FA ++ P F E++ F T S S++ + + D+ ++ L S +PELW N +D+ + AK +LIIQA+RPDRL ++ +F VL +++L I E E + PIL+ G DPS +++L+++ IGS A G QA+ +N ++ G W+ LKN+HL TSWL LEK+++SL+ H +FRL++T E LL++ + +E PPG+K NLLR+ + + +SK R+ F LAW +AI+QER ++P G++K YEF +D + + +D + + I W + L + I+GG++DN FD R+L+S++ F + + + I P + D L +++L D +PS+ LP++ ++ +++++ +L L + K +K W R+L W L I+ S+ L+R+ + P+ + E + L+ V L +++V KG++ T +++ L G P +W++ P ++ D ++ L+ + K ++ L S + LG LF + ++ A RQ A+ K +++EL
Sbjct: 763 VWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNV--SWSLNELQLGKVWDI--DLVKNEEIIREVLAIAQGEKALEEYLRQITEVW-KNYVLELTNY---QSKS-KIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKDLKKLQKHFKKMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASG--VSLESTMT-----VVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNP---GYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTED-GLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVN-IQGTWVAWSNKVPQIEVETHKITATDVVVP---TMDTVRHEALLYTWLAE--HRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAML-RMLP-----SLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVE-GLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALK-----RPILYSNWLS--------------KDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVF-VHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPD-YNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELANVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKG-----------------MYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGS------AEGFSQAEKAIN---SAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPV-ERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLAARLKKDVLTLVATDEAATEDAKQEKGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTW------LQILPKSVT-PLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIA----LRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEEL 4000
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Planmine SMEST
Match: SMESG000033128.1 (SMESG000033128.1) HSP 1 Score: 1205.66 bits (3118), Expect = 0.000e+0 Identity = 956/3588 (26.64%), Postives = 1738/3588 (48.44%), Query Frame = 3
Query: 2628 NKFKEWIILGSLDLEEFVDQHCLDLTDYEKNFKA-------MKTKGKEAEKLPNEIKIDCITVNCAPIKMSVDTLIQNIFDALLNSLRKNIKGTIDSVDAYLTNSIKILSKRPQAIDEIAEATLNHAEFNKDRSRIRSQIDKSEKMNNLLRTVAGGGIDTV----SQLQQKWDKFXXXXXXXXXXXXXXIEVMKTNILSRQKQFQQDIMKFNDRWQGLKPGRDILDSGSTQACLDAVQXXXXXXXXXXXXXXXXTNLEKDCEHFQMEPEEFTLLEEIHKDIDQNQLMWSQFEEYQTGLQNLAKEDWLSFRSRYYLFEEFLTQWFEKLRNAEITTMTI--------------RLQKEIDMYKDIIPILKWIRGEGLSQDHWLEMFRLLNMPRGLTLEALTLRHILDAASEIIRHAEAIKELNQKAQGEVTIREAIRELELWGAGAVFQLVEYIDSQNNSISLIKEWRDIISQVGDNQCLLQSLKDSPYYRFFQDKAAVWENKLADLDEYLQNLNQIQRKWVYLEPIF----GKNALPKEKSRFRRVDEDFRSIMSDVNRNNRVLSLCSMSGMKNLLSTMIDQLQRCQKALNEYLEEKRSLFPRFYFIGDDDLLEILGQSTNPQVIKSHLKKLFQGIYDVDFNKDIQHII---TMKSLDGEVVELRNQVLITSEVENWLGNLNNEMKTTLSDQLSYALQDLRMS---NQSNYGINADKYPSQILCLSEMIHFTARCEELLNENNIITLKKEL--VKKLNIYTNAKMSLSADSTFI-VHDLKLKSLILDTVHNIDIIDQLLDQNCQSVTEWEWLKQLRFYQKSKDQGCVIQMVDAEFNYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGSLFGRQVLVFNCDEGIDVKSMGRIFIGLVKCGSWGCFDEFNRLEEAVLSAVSMQI-QIIQDGIKNKVQEITLLERRVNVDCNSAIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILNSDGFKNAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLKGAANLLEMHKSKMKTQGNDTIENVQDSDFETKLIVQALRVNTLSKLTYADGICFESLIKDVFPNIDIKEIEYDNLASAIEEVIKEQNMVSLKGQHKKMLEVYEQLRQRMGVVIVGPSGSGKSTIWKLLRLALNKIGQTVKF-------YVMNPKAIPRTQLLGHIDIDTREWSDGVLTYSARQVVKEPQEIQSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFIFETHDLSCASPATISRMGMIFLSSEATDVKSLVTSWLKKQ-DEHDQHLLSTYLDDFFYKSLDWIAKRNEFTISTSNVGTVYNG---LSNLKAIKNKAH--------------FSVCLIKGLGGNLNENSRETFALWVYELTDEKTPEMNKQNVLNYYFNEKQNRLVTYSYECEEELSIDQLMSDKKILTPLILTADIQRNLDYFKIWLNSDTQQPFILSGPEGCGKSLMLNHCFQKLKS--VQVTTLHCSAQTTPVHVLQKLNQACIIINSNTGRVYRPKESERLILYLKDINLPKLDKWGTSQLISFLQQVITYKGFYDSNLEFVGLDGVQIVCXXXXXXXXXXXXXXTRFTSIVRLCSISYPSKDQLNDIYTAYLKPVLKRLIPK-HPIWSQNSKVKLLANTMIEVYSQLKSKF-TVDDYSHYLFTPSDLTQWVLSLLRYDLPVTSDNTAVSLLEIVSYESMRIFQDRLVSSDARKRADGILFNTIHSEWSVEVQDSLNDVWFVTWGSREXXXXXXXXXXXXKSLGKLTSEYLKDTIDR-GLLQYSRECRDLDIMLFKEVYDNVAKLDRVLTKPGGSVLLAGKSGVGRRTTSLLVSHMHNIKLISPKMHRGYELKQFKNDLKSTLQTAGVEGEHIVLLLEDHQFLEPQYLELINSLLASGEVPGLYTTEELEPILMSLKDLANESG---HRGSLANYFADRIKHYLHIILIMDCSNLNFVINCQSNPAFFKYCSVQWLEQWSRDSMLKIPYMLINKIPREEGSQLTQNSAKPKTQLTGS------DNLNSYFLDLHDTCPVEFSTSRHYINFIKMYIRIYLKKKNEIETRQNHIQVGIKKISEAKEMVAELKSKAAEQSKLLTEKQLEADKALKKITSVMQGATERKGEMEKLTVKTGEENVILAKRKAAIDDELALIE-----PQVKQARDAVSDIKSSDLSEIRALRAPPDVIRDILEGVLLIMGTMDTSWVSMRNFLGKRGIQEEIQTFDARRITRESRIQVEELLTRCKDSFDPKNAKRASIAAAPLAAWVKANVKYSYALEKIAPLENEQNQLKRNLENAEKKMKDLEKGVSDVDKAVAGYRKDFEKFTADAAKLEFELKNANETISAAEDLVFKLENEFERWNKQIVELNAELSALTIKSLLAAASVIYMPSSPEDQRKEKMQLWMEKTGLEK------FDMRKFLTTEREQLEWKKEGLSSDELSMENALVILQGILIPFLIDPSSNATAWLKNHFKDRKLEIVNQQDSNFSTVLELSVRFGKTLIIQEV-DGLEPVLYPLLRGDLISQGPRQVVQLGDKLIDYNPDFKLFLATRNPQPQLPPDALAIVSTVNFTTTKAGLKGQLLALTMQHVKPKLEERKTNXXXXXXXXXXXXXXXXXXXXQELANATGNIXXXXXXXXXXXXXXESSITISQSLEESVKLQMSLDEERDAFLPLAEHGSSLFFVISDLSKINNMYRFSLTSFLRLFQRALNTSEISTDSTMRNTSLIACLEKLVYEYVCRSIFKSDRLMFALHMSHCCR----PDLFKPQEWELF--TGTFISDKSDRNITVPKWIDA---DRTVAISNLASAMPELWSVLNI-KDDDLWHQFAKSSECEREIPQSLKNKLSLFQKILIIQALRPDRLQSALSQFCCDVLELKHLSPSSMNLHQIYESETISNEPILIIISPGADPSQDLQELSTKVIGSERYNQVAMGQGQADITLNLLHKCSQNGDWLCLKNLHLVTSWLPVLEK---ELNSLKPHKDFRLWVTAEPHIGFSTILLQSSLKITYEAPPGVKNNLLRSYDNWSEDFISKTGSGTRANA-LFSLAWFHAIIQERRNFIPQGWTKFYEFSIADLRAGTEILDQIIKKSNRNIQWKFIHGLFENAIFGGRVDNPFDMRVLSSYIKRYFNDSVVNGSG---NFYGKIQLPSAASKRDYLAIINQLSDYNSPSFFSLPDNIDXXXXXXXXXXVILQLRIL--QRFSVHG-TKFDKDIWSRELNPVLNRWKILNQGLNIIKASLPDSL------KRSSTDS---PVVAFLQLERYNSIKLVKFVHSSLISLSKVLKGSELLTKEVQNLSECLLTGQTPNVWLQQWEGPEEPFDYMRILILKAKAVEKWAELSEKDELLSTILDLGELFHPDTFLNALRQLTARTIKISMDELKF---VCRWGGSNVSA--KYSVKIGNLHIEGCLFD--GTMITECNRDSNSIVLLPPVSVGWVD---KNQPNSYSEDDMISLPIYYDILRDKI------VTKIDIPCQSGQQDKWIQSGVALFL 12986
++F+E + L+ EEF+ Q+C DL + + A + K +AE + + + + ++ + +K S+ ++ L N L ++ + Y+ N + +SK PQ ++E+ E+ + N++R+ I+ + ++ +L D + L+++W +F + + M+++ + KT +L + F++ + +Q P ++ +A+ KI + K LE L I + + + F++E + + KD+D + +W E++T +W ++S ++ E T E L N+ T + +D ++ +P++ +R E + HW ++ + TL I+D + +HAE I E++ A E+ I A++ +E +++ + D + N L+ D+ + DN+ L ++K S + + F+ + WE L+ + E ++ L +QR+W+YLE IF + LPKE + F ++++ +R IM+++N+ + G+ + M L+ QK+L+ YLE KR++FPRFYFI +DDLLEILGQS NP + HLKK F I + K + +M S DGE V + ++ + VE WL +L M+ TL D L+D R++ S ++ Q+ S I +TA + L KK L +KK K S + S + LK+ SL++ VH DII++L C + +EWL QLRFY + + CVI+ + F Y YEY GN+ +LV TPLTD+CY+TLT +H+ GG+P GPAGTGKTE+VK LG G V+V NC EG+D KSMGR+F GL + G+WGCFDEFNR+ VLS V+ QI I+ N + R +++ + IFIT+NP GY GR +LPDNLK +FRP+AM PD+ +IAE+ L ++GF K L +K+ +++LS + L+ Q HYD+GLRAL +VL+ A K + N + + ++++ ++ L+KLT D F+ ++ D+FP ID ++Y N+ AIE+ + K++++YE R V+IVG + SGKST W+LL+ AL ++ + + + +NPK++ +L G D++T EW+DGVL+ R+ + + + WII DG +D WIES+NSV+DDN++LT+ +GERI V+ +FE +LS ASPAT+SR GM++ + V SWLK++ D LS D + K ++I I TS +V + L ++N F C+I + +++E+ R+ ++ E+ + P NK + Y+ + K + + + + + KI+ P + T ++ N + N P +L GP G GK+ + + +L + + T++ SAQT+ +V Q + +A + T + P +R++ ++ D N+P D +G+ + ++Q I Y +YD + + GR +S R S L ++++P++ L I+ + + L+ + PI ++ IE+Y+ + KF HYLF D+++ +LR + +++ L I +E+ R+F DR+V + +L + S + + + +G + L K E L + + G++Q +D++LF++ ++++K+ RV+ +P G++LL G G GR++ + L ++M ++ + Y ++F++DLK AGV+ + + L D Q ++ +LE IN++L+SGE+P LY +E++ + L D A G S+ Y DR++ +H++L M F + PAF ++ W +W D++L++ + + G + ++ KP S +++ LD + + T +Y+ + Y + ++K+ ++ N ++ G+ KI E + V + + E K L Q E D L + V Q +R+ + + +V +E + + + K ELAL + P ++ A A+ + D++EI++ PP +++ ++E V+++ G + +W + LG++ +++ FD I+ + ++ + +D F P + S+AA L WV A Y + P + L + ++ + + V + + ++++ + +L + ++ + + A LV L E +RW K + +L ++ L L+A+A + YM D R+ + W E E+ F +FL+ + +W +GL D S+EN +++ +G P ++DP A W+K + +KL++++ +F VLE++++FG+ +++Q V + L+P L P+L ++ G V++LGDK I+YN DF+ ++ T+ P P P+ VNF + GL+ QLL + ++ +P+LEE+K NL+ K +L+++E+ +L+ L A G++L+++ L+ +L +K +S +++ L+ + K + ++D R + A+ S LFFV++DL KI+ MY+F+L +++ LF ++N S S R ++L VY Y CR +F+ +L+F+ + C + E+ F G + ++ + P W+ D + LA+ + S +D +LW + S +P N + FQ++LI+++LRPDR+ + F + L K + P +++ Q+ + + + ++ ++SPG DP+ L +L+ + +++++ +++GQGQA I ++++ ++ G+W+ L N HL SW+P L+K EL +P FRLW+++ PH F +LQS +K+T E P G+K N+ R Y ED S + LFSL +FH+++ ERR F+ GW YEF+ +D +L + + W + L + +GG V + D R+L++YI YF + + + +P S Y I L + + P F N D +SQ + + L L Q SV G +K D K+L NI K LP+++ K STD VV +++RYN + + L L K ++G +++ +++++ + + + P +W + + + + R L+ + + +KWA + + + + P FL A+ Q +AR IS+D L + V +N+++ K V + L+++G +D +++ E + +P + ++ K+Q NSY P YY R I + +++ + W + G AL +
Sbjct: 1045 DQFRE---IWELNKEEFISQYC-DLNPHVYSIDADISRYTEVTNKALDAEAM---VTVKFLQLDFSMLKNSIAAHCRDWQQKLTNLLLAMATKSLMYLHNYMKNMSEKVSKIPQNLEELGESMRLLDKLNEERNHIQEKFHPLDEHFIILDKYEVQYSDDIRLKKQNLEKEWQEFLQALVEAEQMIKKSKDKFKTGLLVQSDDFKKQVSALIMDFQTNGP------FAASIPPQEALAKIANFKSSLESLKIQEQEIRRGLNLFKIEQPPSKEIAALEKDLDNIENIWKLALEWET--------NWTQWKSGRFI--ELKTTEMENLANSSFRKATKFSRDLKDKNWEIIEYTRNRVDQFRRTMPLITDLRNEAMRDRHWFQIKNEIRKQFDEESSDFTLEKIIDLNFD--QHAEMINEVSGAATKELAIENALKGMEKLWESVELEIIPHKDKEKNHF-LLSGIDDLYQTLDDNRNTLSNMKTSRFVKPFEHEVDKWERDLSHIQETVEMLLTVQRQWLYLENIFLGEDIRKQLPKESADFDKINKQWRVIMTELNQIRNARACGKKEGLLETFNAMNTCLEDIQKSLDMYLETKRNIFPRFYFISNDDLLEILGQSKNPDKVLPHLKKCFDNINSLKIEKLMSQGFEASSMFSSDGEEVLFKQKLRLEGPVEAWLCDLEKCMRVTLRD----LLRDCRIALKKAASKRDKWIKEWSGQLCITSSQIQWTADVTKALQNVAQRNDKKPLRIMKKKQKLVLEKFSEAIRSNLTKIQRLKINSLVVIEVHQRDIIEKLYKSGCSDINAFEWLSQLRFYWEKEIDDCVIKQTNTSFQYGYEYLGNSGRLVITPLTDRCYITLTTALHLHRGGSPKGPAGTGKTETVKDLGKSLGAYVIVVNCSEGLDYKSMGRMFSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSALASNAPPKFMFQGRMIDLVPSVGIFITMNP---GYAGRTELPDNLKSMFRPIAMVTPDSAMIAEITLFAEGFSGCKVLAKKVFTLYSLSIQQLSKQDHYDFGLRALVSVLRYAGR---------KKRANPLMP-------DEEILLLSMNDMNLAKLTSVDLPLFKGIVSDLFPGIDSPVMDYTNMKEAIEKCCDNFQLQPTNFTITKVVQLYETKTSRHSVMIVGKTLSGKSTTWRLLQSALAELSKERESQFEKALEFPLNPKSVSLGELYGEFDLNTNEWTDGVLSSVMRKTCADTRPDEKWIIFDGPVDTLWIESMNSVMDDNKILTLINGERISMPEQVSLLFEVENLSVASPATVSRCGMVYNDVNDLGWRPYVESWLKRKVDSVLVEELSRMFDKYIEKIQNFIKMNCIELIRTSPTNSVISLCKLFDCLATVENGCDPSDTDNYSRVIELWFQFCMIWSICCSVDEDGRKKIDNYIREM-EGTFP--NKDTIYEYFVDNKNKSWGHWDEKLKAGWKYNASVPFYKIIVPTVDT--VRYNYLVQNLVCNF---HPVMLVGPVGTGKTSVAVNTLNQLNNDIWTILTINMSAQTSSNNV-QDIIEARV--EKRTKDTFVPVGGKRMLTFMDDFNMPAKDTFGSQPPLELIRQWIDYGFWYDRLKQTQKRIKDMYLFVAMGPPGGGRMMISNRLQSRFNLINMTFPTESNLKRIFGSMINQKLQDFEEELKPIGD------IITQATIEMYNGVVIKFLPTPTKIHYLFNLRDISKIFQGMLRTNKDYHDTKNSITRLWI--HENFRVFADRMVIDKDKVAFVELLSEKLGSLFDQTFHNICPNKQSPIFGDYMSSTDTYEDITDIEKLKKFMKEMLDEYNNTPGVVQ-------MDLVLFRDAIEHISKIIRVIRQPRGNMLLVGIGGSGRQSLTRLAAYMCEYTSFQIEVSKHYRKQEFRDDLKRLYWQAGVDNKPTLFLFNDTQVVDESFLEDINNILSSGEIPNLYKQDEIDDLRNQLSDEAKRDGIEDTTQSIFTYLIDRVRGNMHVVLCMSPVGEPFRNRIRMFPAFVNCTTIDWFSEWPLDALLEVAERYLKDLQLFIGGE--EDRMKPHLATIFSLMHRSVSDMSQRMLD--EMKRHNYVTPTNYLELVSGYKILLVEKRKQLSDSANKLKNGLGKIDETRAKVEVMSIELEEARKKLAIFQKECDDYL--VVIVQQ---KREADDQAKSVMQTQERIKVDEAKCLKMQELALADLAQAMPALEAAMQALESLNKKDITEIKSYGKPPALVQKVMEAVMILRGA-EPTWAEAKKHLGEQDFIKQLINFDKDNISDRTLKKIGTYV--AQDDFQPDMVGKVSLAAKSLCMWVGAMEVYGRVYRVVEPKRQRLQAAESVLREKQAQLAAAQAKLDAVMEEMKRLQQEYNEKMEQKEELRKKAEHTEKMLDRASKLVSGLAGEKDRWEKTVADLENQIGLLPGDCLIASAFLSYMGPFLSDYREALVIKWTEAIKKEQIPANPSFSFIEFLSNPTQIRDWNIQGLPRDGFSVENGVIVTRGSRWPLMVDPQCQAQKWIK-QMEGKKLKVIDLHMPDFIRVLEIAIQFGQPVLLQNVQEKLDPSLDPILNKSIVKIGGATVMKLGDKEIEYNYDFRFYITTKLPNPHYTPEISTKTCIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDNLVMSIAAGKRKLAELEDEILRLLNEAQGSLLDDEQLVNTLQTSKITSTEVTEQLQIAEKTETAIDIARQGYASCAQRASILFFVLNDLGKIDPMYQFALDAYIDLFNMSINKSTKSPKRDERISNLNDYHTYAVYCYACRGLFEKHKLLFSFQI--CAKILQTSGKMNMDEYNFFLKGGVVLDRENQMDNPCPGWLSDQAWDNISELDKLANFHGLITSFEQYPRDWNLW--YTSDSPETSSLPGEWDNATNEFQRMLIVRSLRPDRVSFCATSFIINNLGNKFVEPPVLDMKQVVDDSS-AKTCLIFVLSPGVDPTSGLLQLAESLGMAKKFHALSLGQGQAPIATRMINEGTKEGNWVFLANCHLSLSWMPQLDKIVEELQIEEPDPKFRLWLSSSPHPEFPISILQSGIKMTTEPPKGLKANMKRLYHLIKEDQFSACRKPEKYKKLLFSLCFFHSVLLERRKFLTLGWNIPYEFNDSDFEVSENLLSNYLDQY-ETTPWDALKYLIADINYGGHVTDDLDRRLLNTYIADYFREEAIKEPFFKLSIMSSYYIPRDGSLNSYREFITMLPNIDHPEAFGQHPNADIASQIQETRLLFDTLLSLKPQVVSVGGDSKED---------------KVLEISGNITK-QLPENIDYEGTAKILSTDPCPLNVVLLQEIQRYNF--QLDLIRKQLSDLEKGIQGLVVMSSDLEDIFDSIYDTKVPRLWSKAYPSMKPLASWTRDLVSRIEMFQKWAITAHAPK----VFWVSAFTFPTGFLTAVIQTSARLNNISVDTLNWDFTVLTISEANIASAPKDGVYVKGLYLQGAGWDMKNSILIEAS-PMELTCAMPVIHFKPIENKKKSQKNSY------ICPCYYYPNRAGISDRPSYIESVELKTGEKAPEHWTKRGTALLM 4509 The following BLAST results are available for this feature:
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Cytoplasmic dynein 2 heavy chain 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1 |
