Ras-related protein Rab-7a

Overview
NameRas-related protein Rab-7a
Smed IDSMED30005661
Length (bp)977
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ras-related protein Rab-7a (SMED30005661) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-related protein Rab-7a (SMED30005661) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-related protein Rab-7a (SMED30005661) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-related protein Rab-7a (SMED30005661) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005661

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30005661h1SMcG0012612 Contig614GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30005661h1SMcG0016245 Contig614GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
protonephridiaSMED30005661h1SMcG0016245 dd_Smed_v4_491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30005661h1SMcG0016245 dd_Smed_v4_491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30005661h1SMcG0016245 dd_Smed_v4_491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30005661h1SMcG0016245 dd_Smed_v4_491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Human
Match: RAB7A (RAB7A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9788])

HSP 1 Score: 337.806 bits (865), Expect = 3.619e-117
Identity = 157/207 (75.85%), Postives = 183/207 (88.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Human
Match: RAB7A (RAB7A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9788])

HSP 1 Score: 270.396 bits (690), Expect = 2.653e-91
Identity = 124/149 (83.22%), Postives = 139/149 (93.29%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDI 530
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNI 149
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Human
Match: RAB7A (RAB7A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9788])

HSP 1 Score: 240.35 bits (612), Expect = 1.897e-79
Identity = 124/207 (59.90%), Postives = 143/207 (69.08%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVL                                               VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVL-----------------------------------------------VATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 160
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Human
Match: RAB9A (RAB9A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9792])

HSP 1 Score: 213.001 bits (541), Expect = 3.985e-68
Identity = 102/202 (50.50%), Postives = 136/202 (67.33%), Query Frame = 3 
Query:   96 KKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            K  L KVI+LGD GVGK+SLMN+YV  KF  Q   TIG +FL KD+ VD   VTMQIWDTAGQERF+SL   FYRG+DCC+L + V   ++F NL +W+ EF+  +  ++P+ FPFV++GNK+D+ ER V++  AQ WC+  GD  YFE SAK+A NV  AF+   R  LA E  +D + +  D +NL   +R+ K S+  C
Sbjct:    4 KSSLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISERQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQ-TDTVNL---HRKPKPSSSCC 201
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Human
Match: RAB9A (RAB9A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9792])

HSP 1 Score: 213.001 bits (541), Expect = 3.985e-68
Identity = 102/202 (50.50%), Postives = 136/202 (67.33%), Query Frame = 3 
Query:   96 KKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            K  L KVI+LGD GVGK+SLMN+YV  KF  Q   TIG +FL KD+ VD   VTMQIWDTAGQERF+SL   FYRG+DCC+L + V   ++F NL +W+ EF+  +  ++P+ FPFV++GNK+D+ ER V++  AQ WC+  GD  YFE SAK+A NV  AF+   R  LA E  +D + +  D +NL   +R+ K S+  C
Sbjct:    4 KSSLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISERQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQ-TDTVNL---HRKPKPSSSCC 201
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Celegans
Match: rab-7 (RAB family [Source:UniProtKB/TrEMBL;Acc:Q23146])

HSP 1 Score: 306.99 bits (785), Expect = 2.528e-105
Identity = 149/206 (72.33%), Postives = 176/206 (85.44%), Query Frame = 3 
Query:   90 SRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDL-GERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQES-EADIINEFPDKINLGDNNREQKTSNCSC 701
            +RKK LLKVIILGDSGVGKTSLMNQYVN++F+NQYKATIGADFLT+DV +DDR VT+QIWDTAGQERFQSLGVAFYRGADCCVL +DVT   +F +L+SWRDEFLIQ+SPRDPDHFPFV++GNKVDL  +R V+S+RAQ WCQ+KG+I Y+E SAKEALNVE AF  +AR ALA+ES E +   EFPD+I L  N + Q+ S C+C
Sbjct:    4 TRKKALLKVIILGDSGVGKTSLMNQYVNRRFSNQYKATIGADFLTRDVNIDDRTVTLQIWDTAGQERFQSLGVAFYRGADCCVLAFDVTNAASFKSLDSWRDEFLIQASPRDPDHFPFVLLGNKVDLESQRAVSSKRAQSWCQTKGNIPYYEVSAKEALNVEAAFLAIARDALARESQETNDFPEFPDQIRLNPNQQNQQNSGCNC 209
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Celegans
Match: rab-7 (RAB family [Source:UniProtKB/TrEMBL;Acc:Q23146])

HSP 1 Score: 306.99 bits (785), Expect = 2.528e-105
Identity = 149/206 (72.33%), Postives = 176/206 (85.44%), Query Frame = 3 
Query:   90 SRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDL-GERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQES-EADIINEFPDKINLGDNNREQKTSNCSC 701
            +RKK LLKVIILGDSGVGKTSLMNQYVN++F+NQYKATIGADFLT+DV +DDR VT+QIWDTAGQERFQSLGVAFYRGADCCVL +DVT   +F +L+SWRDEFLIQ+SPRDPDHFPFV++GNKVDL  +R V+S+RAQ WCQ+KG+I Y+E SAKEALNVE AF  +AR ALA+ES E +   EFPD+I L  N + Q+ S C+C
Sbjct:    4 TRKKALLKVIILGDSGVGKTSLMNQYVNRRFSNQYKATIGADFLTRDVNIDDRTVTLQIWDTAGQERFQSLGVAFYRGADCCVLAFDVTNAASFKSLDSWRDEFLIQASPRDPDHFPFVLLGNKVDLESQRAVSSKRAQSWCQTKGNIPYYEVSAKEALNVEAAFLAIARDALARESQETNDFPEFPDQIRLNPNQQNQQNSGCNC 209
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Celegans
Match: rab-8 (RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5EFC1])

HSP 1 Score: 128.642 bits (322), Expect = 1.078e-35
Identity = 74/206 (35.92%), Postives = 124/206 (60.19%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASR-RAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQ----ESEADIINEFPDKINLGDNNREQKT--SNCSC 701
            L K++++GDSGVGKT ++ ++ +  F N + +TIG DF  + + +D + + +QIWDTAGQERF+++  A+YRGA   +LVYD+T  ++F N+++W    + + +  D +    ++IGNK D+ ER   SR R +Q     G   + E SAK  LN+++AF  +AR   ++    E  A        ++N+G +  ++K+  SN SC
Sbjct:    8 LFKLLLIGDSGVGKTCVLFRFSDDSFNNSFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIILVYDITNERSFENIKNWIRN-IEEHAASDVER---MIIGNKCDIEERREVSRDRGEQLAIEYG-TKFLETSAKANLNIDEAFFTLARDIKSKMEQNEMRAGGSVSNTGRVNVGGSGTQKKSFFSNWSC 208
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Celegans
Match: rab-8 (RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5EFC1])

HSP 1 Score: 128.642 bits (322), Expect = 1.078e-35
Identity = 74/206 (35.92%), Postives = 124/206 (60.19%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASR-RAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQ----ESEADIINEFPDKINLGDNNREQKT--SNCSC 701
            L K++++GDSGVGKT ++ ++ +  F N + +TIG DF  + + +D + + +QIWDTAGQERF+++  A+YRGA   +LVYD+T  ++F N+++W    + + +  D +    ++IGNK D+ ER   SR R +Q     G   + E SAK  LN+++AF  +AR   ++    E  A        ++N+G +  ++K+  SN SC
Sbjct:    8 LFKLLLIGDSGVGKTCVLFRFSDDSFNNSFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIILVYDITNERSFENIKNWIRN-IEEHAASDVER---MIIGNKCDIEERREVSRDRGEQLAIEYG-TKFLETSAKANLNIDEAFFTLARDIKSKMEQNEMRAGGSVSNTGRVNVGGSGTQKKSFFSNWSC 208
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Celegans
Match: unc-108 (pep chromosome:WBcel235:I:3824947:3826514:1 gene:WBGene00006833.1 transcript:F53F10.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-108)

HSP 1 Score: 127.487 bits (319), Expect = 3.780e-35
Identity = 74/188 (39.36%), Postives = 109/188 (57.98%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAAL--AQESEADIINEFPDKINLG 662
            L K II+GD+GVGK+ L+ Q+ +K+F   +  TIG +F  + V +D + + +QIWDTAGQE F+S+  ++YRGA   +LVYD+T   TF +L SW ++    S+     +   ++IGNK DL  R    R   +    +  + + E SAK A NVE+AF + A+      QE   DI NE  + I LG
Sbjct:    6 LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSN----SNMVIMLIGNKSDLEARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRKIQEGVFDINNE-ANGIKLG 188
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Fly
Match: Rab7 (gene:FBgn0015795 transcript:FBtr0084503)

HSP 1 Score: 337.035 bits (863), Expect = 3.938e-117
Identity = 158/207 (76.33%), Postives = 179/207 (86.47%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGD-NNREQKTSNCSC 701
            M+ RKK LLKVIILGDS VGKTSLMNQYVNK+F+NQYKATIGADF TK+V+V+DRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P +F NL+SWRDEFLIQ+SPRDPDHFPFVV+GNKVDL  R V++RRAQQWCQSK DI Y+E SAKE +NVE AFQ +A+ AL  E+EA++IN+FPD+I LG  NNR     NC C
Sbjct:    1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Fly
Match: Rab7 (gene:FBgn0015795 transcript:FBtr0308612)

HSP 1 Score: 337.035 bits (863), Expect = 3.938e-117
Identity = 158/207 (76.33%), Postives = 179/207 (86.47%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGD-NNREQKTSNCSC 701
            M+ RKK LLKVIILGDS VGKTSLMNQYVNK+F+NQYKATIGADF TK+V+V+DRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P +F NL+SWRDEFLIQ+SPRDPDHFPFVV+GNKVDL  R V++RRAQQWCQSK DI Y+E SAKE +NVE AFQ +A+ AL  E+EA++IN+FPD+I LG  NNR     NC C
Sbjct:    1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Fly
Match: Rab7 (gene:FBgn0015795 transcript:FBtr0308611)

HSP 1 Score: 337.035 bits (863), Expect = 3.938e-117
Identity = 158/207 (76.33%), Postives = 179/207 (86.47%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGD-NNREQKTSNCSC 701
            M+ RKK LLKVIILGDS VGKTSLMNQYVNK+F+NQYKATIGADF TK+V+V+DRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P +F NL+SWRDEFLIQ+SPRDPDHFPFVV+GNKVDL  R V++RRAQQWCQSK DI Y+E SAKE +NVE AFQ +A+ AL  E+EA++IN+FPD+I LG  NNR     NC C
Sbjct:    1 MSGRKKSLLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNSFKNLDSWRDEFLIQASPRDPDHFPFVVLGNKVDLDNRQVSTRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNALELEAEAEVINDFPDQITLGSQNNRPGNPDNCQC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Fly
Match: Rab9 (gene:FBgn0032782 transcript:FBtr0081206)

HSP 1 Score: 149.443 bits (376), Expect = 5.674e-43
Identity = 75/165 (45.45%), Postives = 105/165 (63.64%), Query Frame = 3 
Query:   93 RKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLG--ERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAF 581
            +K  LLKV+ILGD GVGK++L+ ++V  ++      TIG +F+ KD++VD    T+QIWDTAGQERF++L   FYRG+D C+L Y +    +   L  WR+EFL   +  D D FPF+V+GNK D+   +R V+S   QQWC  +    + E S+K A NV  AF
Sbjct:    8 QKSKLLKVVILGDGGVGKSALLTRFVANRYEENNFHTIGVEFMNKDIVVDGERYTLQIWDTAGQERFRALRTPFYRGSDICLLCYALDDRDSLKGLGVWRNEFL-NYADVDQDKFPFIVVGNKNDIPAQKRQVSSDAVQQWCAEQKVACHIETSSKAATNVTDAF 171
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Fly
Match: Rab35 (gene:FBgn0031090 transcript:FBtr0333549)

HSP 1 Score: 129.798 bits (325), Expect = 4.277e-36
Identity = 73/197 (37.06%), Postives = 111/197 (56.35%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNC 695
            L K++I+GDSGVGK+SL+ ++ +  F+  Y  TIG DF  + V ++   V +QIWDTAGQERF+++   +YRG    ++VYDVT  ++F N+  W +E  IQ+   + D    V++GNK D  +R V      Q    + DI  FE SAK+ +NVE  F ++ R  L  +       +  D ++L  N +  K   C
Sbjct:    8 LFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEE--IQN---NCDVVKKVLVGNKNDDPDRKVVITEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHKLRTSPNEQQKDTLHLKPNPKGSKGGKC 199
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Zebrafish
Match: rab7a (RAB7a, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040426-1352])

HSP 1 Score: 338.191 bits (866), Expect = 1.850e-117
Identity = 157/207 (75.85%), Postives = 182/207 (87.92%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++  CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDRNDRAKPSAETCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Zebrafish
Match: rab7a (RAB7a, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040426-1352])

HSP 1 Score: 338.191 bits (866), Expect = 1.850e-117
Identity = 157/207 (75.85%), Postives = 182/207 (87.92%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++  CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDRNDRAKPSAETCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Zebrafish
Match: rab7a (RAB7a, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040426-1352])

HSP 1 Score: 338.191 bits (866), Expect = 1.850e-117
Identity = 157/207 (75.85%), Postives = 182/207 (87.92%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++  CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDRNDRAKPSAETCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Zebrafish
Match: rab7a (RAB7a, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040426-1352])

HSP 1 Score: 338.191 bits (866), Expect = 1.850e-117
Identity = 157/207 (75.85%), Postives = 182/207 (87.92%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++  CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDRNDRAKPSAETCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Zebrafish
Match: zgc:100918 (zgc:100918 [Source:ZFIN;Acc:ZDB-GENE-040927-2])

HSP 1 Score: 328.561 bits (841), Expect = 1.185e-113
Identity = 155/206 (75.24%), Postives = 176/206 (85.44%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            M SRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NV+QAFQ +AR AL QESE +   +FPD+I L D+        CSC
Sbjct:    1 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKSNIPYFETSAKEAINVDQAFQTIARNALKQESEVETY-DFPDQIKLRDDRPVSSGDGCSC 205
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Xenopus
Match: rab7a (RAB7A, member RAS oncogene family [Source:NCBI gene;Acc:493388])

HSP 1 Score: 340.117 bits (871), Expect = 4.386e-118
Identity = 159/207 (76.81%), Postives = 182/207 (87.92%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNKVDL  R V ++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKVDLENRQVTTKRAQVWCHSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Xenopus
Match: rab7a (RAB7A, member RAS oncogene family [Source:NCBI gene;Acc:493388])

HSP 1 Score: 288.115 bits (736), Expect = 1.020e-97
Identity = 133/184 (72.28%), Postives = 158/184 (85.87%), Query Frame = 3 
Query:  153 LMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            +++ YVNKKFTNQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNKVDL  R V ++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:   10 VISSYVNKKFTNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKVDLENRQVTTKRAQVWCHSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 193
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Xenopus
Match: MGC75872 (uncharacterized protein mgc75872 [Source:NCBI gene;Acc:394774])

HSP 1 Score: 218.009 bits (554), Expect = 3.785e-70
Identity = 102/181 (56.35%), Postives = 134/181 (74.03%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEAD 626
            M  RK   LK++++G++G GK++LMNQYVN +FTN Y+ATIGADF TK++ V+D+VVT+QIWDTAG ERFQSLG A YRG DCC+LV+DVT P +F  L++W  EFL+Q+ P  P  FPFVVIGNK DL ER V+ R A++WC++  +  YFE SAKE+ NV++AF    + A     E D
Sbjct:    1 MFHRKH--LKLLLIGNAGSGKSALMNQYVNCRFTNYYRATIGADFFTKELRVNDKVVTVQIWDTAGTERFQSLGAALYRGTDCCLLVFDVTSPNSFHALDNWHREFLVQADPVSPGSFPFVVIGNKTDLEERQVSLREAEEWCKTY-NAKYFETSAKESRNVDEAFLEAIKLAFNNHQEPD 178
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Xenopus
Match: vasp (vasodilator stimulated phosphoprotein [Source:Xenbase;Acc:XB-GENE-6454542])

HSP 1 Score: 209.534 bits (532), Expect = 7.780e-67
Identity = 103/205 (50.24%), Postives = 138/205 (67.32%), Query Frame = 3 
Query:   90 SRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEAD-IINEFPDKINLGDNNREQKTSNCSC 701
            S K  LLK+I+LGD GVGK+SLMN+YV  KF  Q   TIG +FL K++ VD  +VTMQIWDTAGQERF+SL   FYRG+DCC+L + V   ++F NL +W+ EF+  +  +DPD FPFV++GNK+D+ +R V+   AQ WC+  G+  YFE SAK+A NV  AF+   R  LA E  +D +IN   D +NL   +R+ K +   C
Sbjct:    2 SAKSSLLKIILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKELEVDGHLVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLTNWKKEFIYYADVKDPDSFPFVILGNKIDITDRQVSVEEAQAWCRDNGNNPYFETSAKDATNVAAAFEEAVRRVLAIEDRSDQLINT--DTVNL---HRKPKPTTACC 201
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Xenopus
Match: rab9b (RAB9B, member RAS oncogene family [Source:NCBI gene;Acc:780136])

HSP 1 Score: 207.994 bits (528), Expect = 3.118e-66
Identity = 97/179 (54.19%), Postives = 127/179 (70.95%), Query Frame = 3 
Query:   90 SRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEAD 626
            S K +LLKVI+LGD GVGK+SLMN+YV  KF +Q   TIG +FL +D+ VD R+VT+QIWDTAGQERF+SL   FYRGADCC+L + V   ++F NL SWR EF++ +  ++PD FPFVV+GNKVD  ER +++  A+ WC   G   Y E SAK+  NV+ AF+   R ALA E + +
Sbjct:    2 SGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRLVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLSSWRKEFILYADVKEPDRFPFVVLGNKVDKSEREISTVDAETWCNENGGYPYLETSAKDDTNVDGAFEEAVRQALAVEEQVE 180
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Mouse
Match: Rab7 (RAB7, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105068])

HSP 1 Score: 337.806 bits (865), Expect = 2.485e-117
Identity = 157/207 (75.85%), Postives = 183/207 (88.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Mouse
Match: Rab7 (RAB7, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105068])

HSP 1 Score: 337.806 bits (865), Expect = 2.485e-117
Identity = 157/207 (75.85%), Postives = 183/207 (88.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Mouse
Match: Rab7 (RAB7, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105068])

HSP 1 Score: 337.806 bits (865), Expect = 2.485e-117
Identity = 157/207 (75.85%), Postives = 183/207 (88.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Mouse
Match: Rab7 (RAB7, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105068])

HSP 1 Score: 337.806 bits (865), Expect = 2.485e-117
Identity = 157/207 (75.85%), Postives = 183/207 (88.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Mouse
Match: Rab7 (RAB7, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105068])

HSP 1 Score: 337.806 bits (865), Expect = 2.485e-117
Identity = 157/207 (75.85%), Postives = 183/207 (88.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. UniProt/SwissProt
Match: sp|P18067|RAB7A_CANLF (Ras-related protein Rab-7a OS=Canis lupus familiaris OX=9615 GN=RAB7A PE=1 SV=1)

HSP 1 Score: 338.191 bits (866), Expect = 1.701e-116
Identity = 157/207 (75.85%), Postives = 183/207 (88.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKTSAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. UniProt/SwissProt
Match: sp|P51150|RAB7A_MOUSE (Ras-related protein Rab-7a OS=Mus musculus OX=10090 GN=Rab7a PE=1 SV=2)

HSP 1 Score: 337.806 bits (865), Expect = 1.738e-116
Identity = 157/207 (75.85%), Postives = 183/207 (88.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. UniProt/SwissProt
Match: sp|P51149|RAB7A_HUMAN (Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1)

HSP 1 Score: 337.806 bits (865), Expect = 1.738e-116
Identity = 157/207 (75.85%), Postives = 183/207 (88.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. UniProt/SwissProt
Match: sp|P09527|RAB7A_RAT (Ras-related protein Rab-7a OS=Rattus norvegicus OX=10116 GN=Rab7a PE=1 SV=2)

HSP 1 Score: 337.806 bits (865), Expect = 2.071e-116
Identity = 157/207 (75.85%), Postives = 182/207 (87.92%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R VA++RAQ WC SK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N R + ++ +CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNERAKASAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. UniProt/SwissProt
Match: sp|H9BW96|RAB7_EPICO (Ras-related protein rab7 OS=Epinephelus coioides OX=94232 GN=rab7 PE=1 SV=1)

HSP 1 Score: 337.421 bits (864), Expect = 2.605e-116
Identity = 157/207 (75.85%), Postives = 181/207 (87.44%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N R + ++  CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDRNERAKPSAETCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. TrEMBL
Match: A0A1S3H716 (ras-related protein Rab-7a OS=Lingula unguis OX=7574 GN=LOC106152747 PE=4 SV=1)

HSP 1 Score: 348.591 bits (893), Expect = 2.945e-118
Identity = 160/206 (77.67%), Postives = 184/206 (89.32%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            M+SRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVTMP TF  L+SWRDEFLIQ+SPRDP+HFPFVVIGNK+DL  R V+++RAQ WC SKGDI YFE SAKEA+NVEQAFQ VA+ ALAQE+E ++ NEFPD+I L + +  +K   C+C
Sbjct:    1 MSSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTMPNTFKTLDSWRDEFLIQASPRDPEHFPFVVIGNKIDLENRAVSTKRAQGWCHSKGDIPYFETSAKEAINVEQAFQTVAKNALAQETEVELYNEFPDQIKLTNADANKKQDGCAC 206
[Close]
BLAST of Ras-related protein Rab-7a vs. TrEMBL
Match: A0A212F3Y1 (Rab7 OS=Danaus plexippus plexippus OX=278856 GN=KGM_204401 PE=4 SV=1)

HSP 1 Score: 347.821 bits (891), Expect = 7.100e-118
Identity = 163/208 (78.37%), Postives = 186/208 (89.42%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPD--KINLGDNNREQKTSNCSC 701
            M+SRKK+LLKVIILGDSGVGKTSLMNQ+VNKKF+NQYKATIGADFLTK+VIVDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF +LESWRDEFLIQ+SPRDPD+FPFV++GNKVDL  R V+++RAQQWCQSK DI YFE SAKEA+NVE AFQ +AR ALAQE+EA++ NEFPD  K+N  DN R +   NC+C
Sbjct:    1 MSSRKKVLLKVIILGDSGVGKTSLMNQFVNKKFSNQYKATIGADFLTKEVIVDDRIVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKSLESWRDEFLIQASPRDPDNFPFVILGNKVDLENRAVSAKRAQQWCQSKNDIPYFETSAKEAVNVELAFQTIARNALAQETEAELYNEFPDQIKLNANDNGRNRDGDNCAC 208
[Close]
BLAST of Ras-related protein Rab-7a vs. TrEMBL
Match: A0A0L7LFE6 (Rab7 OS=Operophtera brumata OX=104452 GN=OBRU01_09328 PE=4 SV=1)

HSP 1 Score: 347.436 bits (890), Expect = 9.232e-118
Identity = 163/208 (78.37%), Postives = 186/208 (89.42%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPD--KINLGDNNREQKTSNCSC 701
            M+SRKK+LLKVIILGDSGVGKTSLMNQ+VNKKF+NQYKATIGADFLTK+VIVDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF +LESWRDEFLIQ+SPRDPD+FPFV++GNKVDL  R V+++RAQQWCQSK DI YFE SAKEA+NVE AFQ +AR ALAQE+EA++ NEFPD  K+N  DN R +   NC+C
Sbjct:    1 MSSRKKVLLKVIILGDSGVGKTSLMNQFVNKKFSNQYKATIGADFLTKEVIVDDRIVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKSLESWRDEFLIQASPRDPDNFPFVILGNKVDLDNRAVSAKRAQQWCQSKNDIPYFETSAKEAVNVELAFQTIARNALAQETEAELYNEFPDQIKLNANDNARNRDGDNCAC 208
[Close]
BLAST of Ras-related protein Rab-7a vs. TrEMBL
Match: A0A2A4K037 (Uncharacterized protein OS=Heliothis virescens OX=7102 GN=B5V51_6840 PE=4 SV=1)

HSP 1 Score: 347.436 bits (890), Expect = 9.645e-118
Identity = 163/208 (78.37%), Postives = 185/208 (88.94%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPD--KINLGDNNREQKTSNCSC 701
            M+SRKK+LLKVIILGDSGVGKTSLMNQ+VNKKF+NQYKATIGADFLTK+VIVDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF +LESWRDEFLIQ+SPRDPD+FPFV++GNKVDL  R V+++RAQQWCQSK DI YFE SAKEA+NVE AFQ +AR ALAQE EA++ NEFPD  K+N  DN R +   NC+C
Sbjct:    1 MSSRKKVLLKVIILGDSGVGKTSLMNQFVNKKFSNQYKATIGADFLTKEVIVDDRIVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKSLESWRDEFLIQASPRDPDNFPFVILGNKVDLDNRAVSAKRAQQWCQSKNDIPYFETSAKEAVNVELAFQTIARNALAQEKEAELFNEFPDQIKLNANDNGRNRDGDNCAC 208
[Close]
BLAST of Ras-related protein Rab-7a vs. TrEMBL
Match: R7V5G0 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_21782 PE=4 SV=1)

HSP 1 Score: 346.665 bits (888), Expect = 1.691e-117
Identity = 162/206 (78.64%), Postives = 185/206 (89.81%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT+P TF  L+SWRDEFLIQ+SPRDP++FPFVVIGNK+DL  R V++RRAQQWCQ+KGDI YFE SAKEA+NVEQAFQ VA+ ALAQE+E ++ NEFPD+I L  N++ +    C C
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTVPNTFKTLDSWRDEFLIQASPRDPENFPFVVIGNKIDLENRAVSTRRAQQWCQTKGDIPYFETSAKEAINVEQAFQTVAKNALAQETEVELYNEFPDQIKLS-NDQNKPKDGCGC 205
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Cavefish
Match: ENSAMXT00000041258.1 (RAB7A, member RAS oncogene family [Source:NCBI gene;Acc:103037857])

HSP 1 Score: 338.191 bits (866), Expect = 1.485e-117
Identity = 157/207 (75.85%), Postives = 181/207 (87.44%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            M SRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+V+DR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P TF  L+SWRDEFLIQ+SPRDPD+FPFVV+GNK+DL  R V ++RAQ WCQSK ++ YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFPD I L  N+R   ++ +CSC
Sbjct:    1 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVEDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPTTFKTLDSWRDEFLIQASPRDPDNFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNMPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPDPIKLDRNDRSSPSAESCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Cavefish
Match: rab7a (ras-related protein rab7 [Source:NCBI gene;Acc:103043048])

HSP 1 Score: 338.191 bits (866), Expect = 1.568e-117
Identity = 157/207 (75.85%), Postives = 182/207 (87.92%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTS-NCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L  N+R + ++  CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDRNDRAKPSAETCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Cavefish
Match: rab7b (ras-related protein rab7-like [Source:NCBI gene;Acc:103037223])

HSP 1 Score: 327.02 bits (837), Expect = 3.343e-113
Identity = 154/206 (74.76%), Postives = 176/206 (85.44%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            M SRKK+LLKVIILGDSGVGKTSLMNQYVN KF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NV+QAFQ +AR AL QESE +   +FPD+I L D+     +  CSC
Sbjct:    1 MASRKKVLLKVIILGDSGVGKTSLMNQYVNNKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNIPYFETSAKEAINVDQAFQTIARNALKQESEVEPY-DFPDQIKLRDDRPASSSDGCSC 205
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Cavefish
Match: ENSAMXT00000002303.2 (RAB7A, member RAS oncogene family [Source:NCBI gene;Acc:103037857])

HSP 1 Score: 312.383 bits (799), Expect = 3.147e-107
Identity = 147/192 (76.56%), Postives = 166/192 (86.46%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINL 659
            M SRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+V+DR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P TF  L+SWRDEFLIQ+SPRDPD+FPFVV+GNK+DL  R V ++RAQ WCQSK ++ YFE SAKEA+NVEQAFQ +AR AL Q S      + P  I+L
Sbjct:    1 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVEDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPTTFKTLDSWRDEFLIQASPRDPDNFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNMPYFETSAKEAINVEQAFQTIARNALKQVSSTP---DIPQHIDL 189
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Cavefish
Match: ENSAMXT00000055036.1 (RAB7A, member RAS oncogene family [Source:NCBI gene;Acc:103037857])

HSP 1 Score: 312.383 bits (799), Expect = 3.147e-107
Identity = 147/192 (76.56%), Postives = 166/192 (86.46%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINL 659
            M SRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+V+DR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVT P TF  L+SWRDEFLIQ+SPRDPD+FPFVV+GNK+DL  R V ++RAQ WCQSK ++ YFE SAKEA+NVEQAFQ +AR AL Q S      + P  I+L
Sbjct:    1 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVEDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTAPTTFKTLDSWRDEFLIQASPRDPDNFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNMPYFETSAKEAINVEQAFQTIARNALKQVSSTP---DIPQHIDL 189
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Sea Lamprey
Match: rab30 (RAB30, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040718-250])

HSP 1 Score: 133.65 bits (335), Expect = 4.203e-38
Identity = 74/182 (40.66%), Postives = 110/182 (60.44%), Query Frame = 3 
Query:  102 ILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGE-RNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFP 644
            +L K++++G++GVGKT L+ ++    F     ATIG DF+ K V VD   + +QIWDTAGQERF+S+  ++YR A   VL YDV+  +TF  L +W  E    +S     H P V++GNK+DL + R V   +A+ + +  G + Y E SAKEA NVE+ F  +AR  LA ++    + + P
Sbjct:    8 LLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVDGTKIKLQIWDTAGQERFRSITQSYYRSAHALVLTYDVSSEETFACLPAWLREMEQHAS----AHVPRVLVGNKLDLADVRQVTREQAEAFARLHG-LRYLETSAKEAENVERLFVELAR-RLALDARQPALGDAP 183
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Sea Lamprey
Match: rab2a (RAB2A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-011212-2])

HSP 1 Score: 129.028 bits (323), Expect = 2.335e-36
Identity = 77/211 (36.49%), Postives = 115/211 (54.50%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALA--QESEADIINEFPDKINLG------------DNNREQKTSNC 695
            L K II+GD+GVGK+ L+ Q+ +K+F   +  TIG +F  + + +D + V +QIWDTAGQE F+S+  ++YRGA   +LVYD+T   TF +L +W ++    S+     +   ++IGNK DL  R    R   +    +  + + E SAK A NVE+AF N A+      QE   DI NE  + I +G              NR+Q+   C
Sbjct:    6 LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNS----NMVIMLIGNKSDLESRREVKREEGEAFAREHGLVFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNE-ANGIKIGPQHAASSPGMASSQNRQQQDGGC 211
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Sea Lamprey
Match: rab8a (RAB8A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-070424-36])

HSP 1 Score: 127.102 bits (318), Expect = 1.075e-35
Identity = 71/201 (35.32%), Postives = 118/201 (58.71%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDK--INLGDNNREQKTSNCSC 701
            L K++++GDSGVGKT ++ ++    F + + +TIG DF  + + +D + + +QIWDTAGQERF+++  A+YRGA   +LVYD+T  K+F N+++W       +S  D +    +++GNK D+ ER   +R   +    +  I + E SAK ++NVE+AF  +AR   A+       N  PD   + +   ++ +KTS   C
Sbjct:    8 LFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIDLDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFENIKNWIRNIEEHASA-DVEK---MILGNKCDMNERRQVTRERGEKLAIEYGIKFMETSAKASINVEEAFFTLARDIKAKMDRKLEGNNTPDSNAVRITAPSQGKKTSFFRC 204
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Sea Lamprey
Match: RAB2B (RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246])

HSP 1 Score: 126.331 bits (316), Expect = 1.290e-35
Identity = 66/164 (40.24%), Postives = 99/164 (60.37%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVAR 596
            L K II+GD+GVGK+ L+ Q+ +K+F   +  TIG +F  + + +D + V +QIWDTAGQE F+S+  ++YRGA   +LVYD+T   TF +L +W ++    SS     +   ++IGNK DL  R    R   +    +  + + E SAK A NVE+AF N A+
Sbjct:   11 LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSS----NMIIMLIGNKSDLESRRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAK 170
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000009.1 (pep scaffold:Pmarinus_7.0:GL476426:408368:444599:1 gene:ENSPMAG00000000008.1 transcript:ENSPMAT00000000009.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 127.487 bits (319), Expect = 1.304e-35
Identity = 75/215 (34.88%), Postives = 117/215 (54.42%), Query Frame = 3 
Query:   63 NQNLITKMTSRKKIL-LKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVAS-RRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDN-NREQKTSNCS 698
            N      + S  KIL  K+++LG+S VGK+SL+ ++V  +F    ++TIGA FLT+ V ++D  V  +IWDTAGQER+ SL   +YRGA   ++VYD+T   TF+  ++W  E   Q+SP    +    + GNK DL  + +     AQ +    G + + E SAK A+NV   F  +A+  L +        +    ++LG   +  Q+ + CS
Sbjct:   11 NGTTAGALASTSKILQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLEDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQDTFSRAKTWVKELQRQASP----NIVIALAGNKADLASKRIVEFEEAQSYADDNG-LLFMETSAKTAMNVNDIFLAIAK-KLPRSEPPGTGTKAHGMVSLGPGPDSHQRRTCCS 219
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Yeast
Match: YPT7 (Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion; localizes to sites of contact between the vacuole and mitochondria (vCLAMPs); interacts with the cargo selection/retromer complex for retrograde sorting; similar to mammalian Rab7 [Source:SGD;Acc:S000004460])

HSP 1 Score: 251.136 bits (640), Expect = 4.321e-84
Identity = 128/215 (59.53%), Postives = 166/215 (77.21%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVD-DRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGE--RNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEAD---IINEFPDKINL---GDNNREQKTSNCSC 701
            M+SRKK +LKVIILGDSGVGKTSLM++YVN K++ QYKATIGADFLTK+V VD D+V TMQ+WDTAGQERFQSLGVAFYRGADCCVLVYDVT   +F N++SWRDEFL+ ++   P+ FPFV++GNK+D  E  + V+ + AQ+  +S GDI  F  SAK A+NV+ AF+ +AR+AL Q+++AD     +++ D IN+   G+NN      +CSC
Sbjct:    1 MSSRKKNILKVIILGDSGVGKTSLMHRYVNDKYSQQYKATIGADFLTKEVTVDGDKVATMQVWDTAGQERFQSLGVAFYRGADCCVLVYDVTNASSFENIKSWRDEFLVHANVNSPETFPFVILGNKIDAEESKKIVSEKSAQELAKSLGDIPLFLTSAKNAINVDTAFEEIARSAL-QQNQADTEAFEDDYNDAINIRLDGENN------SCSC 208
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Yeast
Match: VPS21 (Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication [Source:SGD;Acc:S000005615])

HSP 1 Score: 126.716 bits (317), Expect = 1.250e-35
Identity = 72/208 (34.62%), Postives = 113/208 (54.33%), Query Frame = 3 
Query:  108 LKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDL----GERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVA-----RAALAQESEADIINEFPDKINL-GDNNREQKTSNCSC 701
            +K+++LG++ VGK+S++ ++V+  F    + TIGA FLT+ V +++  V  +IWDTAGQERF SL   +YR A   ++VYDVT P++F     W  E   Q+S          ++GNK+D+    GER VA    ++  + KG + +FE SAK   NV   F  +      + A  Q S ++       +++L   N+     S CSC
Sbjct:    8 IKLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASK----DIIIALVGNKIDMLQEGGERKVAREEGEKLAEEKG-LLFFETSAKTGENVNDVFLGIGEKIPLKTAEEQNSASNERESNNQRVDLNAANDGTSANSACSC 210
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Yeast
Match: YPT6 (Rab family GTPase; required for endosome-to-Golgii, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6 [Source:SGD;Acc:S000004252])

HSP 1 Score: 126.331 bits (316), Expect = 2.112e-35
Identity = 68/209 (32.54%), Postives = 120/209 (57.42%), Query Frame = 3 
Query:  111 KVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLG-ERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALA-QESEADIINEFPDKINLGDNNR----------EQKTSNCSC 701
            K++ LG+ GVGKTSL+ +++   F + Y+ATIG DFL+K + +DD+ + +Q+WDTAGQERF+SL  ++ R +   ++VYD+T  K+F  ++ W ++     + R  ++    ++GNK DL  ER +++   ++  +  G   + E S K   NV+  F+ +A++    Q SE+  ++   +  N  + N+          EQ+ S C C
Sbjct:   12 KIVFLGEQGVGKTSLITRFMYDTFDDHYQATIGIDFLSKTMYLDDKTIRLQLWDTAGQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYIDKWIEDV---KNERGDENVILCIVGNKSDLSDERQISTEEGEKKAKLLGAKIFMETSTKAGYNVKALFKKIAKSLPEFQNSESTPLD--SENANSANQNKPGVIDISTAEEQEQSACQC 215
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Yeast
Match: SEC4 (Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889])

HSP 1 Score: 122.479 bits (306), Expect = 4.550e-34
Identity = 66/170 (38.82%), Postives = 103/170 (60.59%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQE 614
            ++K++++GDSGVGK+ L+ ++V  KF   +  TIG DF  K V ++ + V +Q+WDTAGQERF+++  A+YRGA   +LVYDVT  +TFTN++ W        +    D    +++GNK D+  R V + + +   +  G I + E SAK   NV + F  +A+  L QE
Sbjct:   20 IMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQW----FKTVNEHANDEAQLLLVGNKSDMETRVVTADQGEALAKELG-IPFIESSAKNDDNVNEIFFTLAK--LIQE 182
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Yeast
Match: YPT1 (Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles [Source:SGD;Acc:S000001856])

HSP 1 Score: 119.398 bits (298), Expect = 6.308e-33
Identity = 65/195 (33.33%), Postives = 113/195 (57.95%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVAR---AALAQESEADIINEFPDKINL 659
            M S    L K++++G+SGVGK+ L+ ++ +  +TN Y +TIG DF  K V +D + V +QIWDTAGQERF+++  ++YRG+   ++VYDVT  ++F  ++ W  E    ++         +++GNK DL ++ V      +       + + E SA ++ NVE AF  +AR    +++Q++  +   +  DK N+
Sbjct:    1 MNSEYDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATST----VLKLLVGNKCDLKDKRVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQIKESMSQQNLNETTQKKEDKGNV 191
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Nematostella
Match: EDO45332 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT62])

HSP 1 Score: 332.798 bits (852), Expect = 8.622e-116
Identity = 153/206 (74.27%), Postives = 181/206 (87.86%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            M SRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P +F  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V+++RAQ WC SK DI YFE SAKEA+NVEQAFQ +A+ ALAQE++ ++ N+FPD+I L  + +  K  NC+C
Sbjct:    1 MASRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTQPNSFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRAVSAKRAQAWCHSKNDIPYFETSAKEAINVEQAFQTIAKNALAQETDVELYNDFPDQIKLSGDTKP-KQDNCAC 205
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Nematostella
Match: EDO34695 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNL1])

HSP 1 Score: 187.963 bits (476), Expect = 5.886e-59
Identity = 89/164 (54.27%), Postives = 114/164 (69.51%), Query Frame = 3 
Query:   90 SRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAF 581
            S K  LLKV++LGD GVGK+SLMN++V  KF  Q   TIG +FL KDV +D    T+QIWDTAGQERF+SL   FYRG+D C+LVY V   K+FTNL  W+ EFL  +  RD ++FPF+++GNKVD+  R V+   A  WC+  G + YFE SAK++ NV  AF
Sbjct:    2 SGKSTLLKVVLLGDGGVGKSSLMNRFVCGKFDTQSFHTIGVEFLNKDVKLDGESYTLQIWDTAGQERFKSLRTPFYRGSDLCLLVYAVDDAKSFTNLSMWKKEFLYYADVRDQENFPFILLGNKVDVEGRAVSQEEADSWCRQNGGVPYFETSAKDSTNVNDAF 165
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Nematostella
Match: EDO42144 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2G3])

HSP 1 Score: 134.806 bits (338), Expect = 2.513e-38
Identity = 75/201 (37.31%), Postives = 118/201 (58.71%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGE-RNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVAR-------AALAQESEADIINEFPDKINLG 662
            M S    L K++++GDSGVGK+SL+ ++ +  F+N Y +TIG DF  + + VD + + +QIWDTAGQERF++L  A+YR A   VL+YDV   +TF +L  W +E     S    +    +++GNK DL + R V    A+++ + K DI++ E SAK++ NVE  F+ +A        + L   +  D  +  P K++ G
Sbjct:    1 MNSEYDYLFKLLLIGDSGVGKSSLLLRFADDTFSNTYISTIGVDFKIRTLTVDGKTIKLQIWDTAGQERFRTLTTAYYRSAHGIVLIYDVNESETFLHLSQWLEEV----SEYACEGVNTILVGNKCDLIDCRQVGYNTAKEFAE-KLDISFIETSAKDSTNVESVFRTMAAELKAKLGSPLTSPTAGDSTDACPLKLSDG 196
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Nematostella
Match: EDO33074 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST94])

HSP 1 Score: 134.42 bits (337), Expect = 4.044e-38
Identity = 68/161 (42.24%), Postives = 107/161 (66.46%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGE-RNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQ 584
            L K++++GDSGVGK+SL++++   +F  + K+TIG +F T+ + V+ +++  Q+WDTAGQER++++  A+YRGA   VLVYD+T  KTF ++E W  E    + P        +++GNK DL   R VAS  A+++    G +A+ E SA +A NVE+AFQ
Sbjct:   12 LYKIVLIGDSGVGKSSLLSRFTRNEFDIESKSTIGVEFATRSIQVEGKIIKAQVWDTAGQERYRAITSAYYRGAVGAVLVYDLTKQKTFQDVERWLLEVREHADPT----IVVMLVGNKCDLKHLRAVASDDAKKYGDEHG-LAFIEASALDATNVEEAFQ 167
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Nematostella
Match: EDO47471 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMA6])

HSP 1 Score: 134.035 bits (336), Expect = 4.435e-38
Identity = 73/198 (36.87%), Postives = 117/198 (59.09%), Query Frame = 3 
Query:  105 LLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASR-RAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNC 695
            L K++++GDSGVGKT ++ ++ +  F   + +TIG DF  K + +  + + +QIWDTAGQERF ++  ++YRGA   +LVYD+T  KTF N+  W    L        +    +++GNK D+ +R + SR R +Q  +  G I + E SAK  +N+EQAFQ +A+  L +E   D  +E P   N+  ++++ K   C
Sbjct:    9 LFKLLLIGDSGVGKTCILFRFSDDAFNTTFISTIGIDFKIKTIEMQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITQEKTFDNISKW----LRNIEEHANEDVEKMILGNKCDMDDRRIVSRERGEQIAREHG-IRFLETSAKTNINIEQAFQYLAQDILKKELNKD--SEEPSN-NIHVHDQKDKKGGC 198
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Medaka
Match: rab7a (ras-related protein rab7 [Source:NCBI gene;Acc:101157689])

HSP 1 Score: 336.265 bits (861), Expect = 7.930e-117
Identity = 155/206 (75.24%), Postives = 178/206 (86.41%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NVEQAFQ +AR AL QE+E ++ NEFP+ I L     +  +  CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLRSEPPKPSSEPCSC 206
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Medaka
Match: ENSORLT00000021125.2 (RAB7A, member RAS oncogene family [Source:NCBI gene;Acc:101157360])

HSP 1 Score: 332.028 bits (850), Expect = 4.593e-115
Identity = 155/207 (74.88%), Postives = 181/207 (87.44%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSN-CSC 701
            MTSRKK+LLKVIILGDSGVGKTSLMNQYVNKKF+NQYKATIGADFLTK+V+VDDR+VTMQIWDTAGQERFQSLGVAFYRGADCCVLV+DVT P TF  L+SWRDEFLIQ+SPRDP++FPFVV+GNK+DL  R V ++RAQ WCQSK +I YFE SAKEA+NVEQAFQ +AR AL QE+E +   +FP+ I L  N+R + +++ CSC
Sbjct:    1 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVTTKRAQAWCQSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVEPYPDFPEPIKLDRNDRAKASADSCSC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Medaka
Match: si:dkey-13a21.4 (ras-related protein rab7-like [Source:NCBI gene;Acc:101165549])

HSP 1 Score: 213.386 bits (542), Expect = 1.575e-68
Identity = 98/198 (49.49%), Postives = 133/198 (67.17%), Query Frame = 3 
Query:  102 ILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNC 695
            + LK+I++G+SGVGK+S MN+YVN +FTN Y+AT+G DF +K  ++D   V +QIWDTAG ERFQSLG   YRG+ CC+LV+DVT   +F  L++WR EFL+Q  P DP  FPF+V+GNK DL +R V+SR+AQQWC+  G   YFE SAK  ++VE  F   A+ AL Q  +  + N    +I      + + T  C
Sbjct:    8 LTLKIILIGNSGVGKSSFMNRYVNHRFTNAYRATVGTDFFSKKTVLDGEPVILQIWDTAGTERFQSLGTPLYRGSHCCLLVFDVTSSASFGALDAWRKEFLVQGEPLDPSDFPFIVLGNKTDLSDREVSSRKAQQWCEEVG-AEYFEGSAKADVDVEPPFNRAAKLALQQYKKHTLENTGHFQITCEQPRKTRDTCMC 204
[Close]
BLAST of Ras-related protein Rab-7a vs. Ensembl Medaka
Match: rab9b (RAB9B, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-091118-112])

HSP 1 Score: 206.453 bits (524), Expect = 9.850e-66
Identity = 100/202 (49.50%), Postives = 132/202 (65.35%), Query Frame = 3 
Query:   90 SRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNC 695
            S K +LLKVI+LGD GVGK+SLMN+YV  +F +Q   TIG +FL +D++VD R+VT+QIWDTAGQERF+SL   FYRGADCC+L + V   ++F NL  W+ EF+  S  +DP+ F FVV+GNKVD+  R V    A+ WC+  G   YFE SAK+  NV  AF+   R  LA E + D        I+L  N +  ++S C
Sbjct:   10 SGKNLLLKVILLGDGGVGKSSLMNRYVTDRFDSQSFHTIGVEFLNRDMVVDGRLVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFAVNDSRSFQNLNCWKREFINYSDVKDPERFSFVVLGNKVDVEHREVGEVEARAWCEENGSYPYFETSAKDDTNVAAAFEAAVREVLATEDQMDHA-LLSSTIDLHGNRKTSRSSCC 210
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BLAST of Ras-related protein Rab-7a vs. Ensembl Medaka
Match: si:dkey-13a21.4 (ras-related protein rab7-like [Source:NCBI gene;Acc:101165549])

HSP 1 Score: 206.068 bits (523), Expect = 1.228e-65
Identity = 90/166 (54.22%), Postives = 120/166 (72.29%), Query Frame = 3 
Query:  102 ILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARA 599
            + LK+I++G+SGVGK+S MN+YVN +FTN Y+AT+G DF +K  ++D   V +QIWDTAG ERFQSLG   YRG+ CC+LV+DVT   +F  L++WR EFL+Q  P DP  FPF+V+GNK DL +R V+SR+AQQWC+  G   YFE SAK  ++VE  F    + 
Sbjct:    8 LTLKIILIGNSGVGKSSFMNRYVNHRFTNAYRATVGTDFFSKKTVLDGEPVILQIWDTAGTERFQSLGTPLYRGSHCCLLVFDVTSSASFGALDAWRKEFLVQGEPLDPSDFPFIVLGNKTDLSDREVSSRKAQQWCEEVG-AEYFEGSAKADVDVEPPFNRALKG 172
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BLAST of Ras-related protein Rab-7a vs. Planmine SMEST
Match: SMESG000068863.1 (SMESG000068863.1)

HSP 1 Score: 430.254 bits (1105), Expect = 5.252e-154
Identity = 206/206 (100.00%), Postives = 206/206 (100.00%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC
Sbjct:    1 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 206
[Close]
BLAST of Ras-related protein Rab-7a vs. Planmine SMEST
Match: SMESG000014290.1 (SMESG000014290.1)

HSP 1 Score: 331.643 bits (849), Expect = 4.316e-115
Identity = 170/207 (82.13%), Postives = 182/207 (87.92%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADI-INEFPDKINLGDNNREQKTSNCSC 701
            M SRKKILLK+IILGDSGVGKTSLMNQ+VN+KFTNQYKATIGADFLTKDV+VDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDV MP TF  LESWRDEFLIQS PRDP+ FPFVVIGNKVDL  R VA+RRAQQWCQSKGDI YFECSAK+A+NVEQAF  VARAALAQESE DI  +  PD+I+L D NR  K + C C
Sbjct:    1 MASRKKILLKIIILGDSGVGKTSLMNQFVNRKFTNQYKATIGADFLTKDVMVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVAMPNTFKTLESWRDEFLIQSGPRDPEKFPFVVIGNKVDLESRAVAARRAQQWCQSKGDIPYFECSAKDAINVEQAFNAVARAALAQESEIDICCSVIPDQIHLKDENRNTKQNGCGC 207
[Close]
BLAST of Ras-related protein Rab-7a vs. Planmine SMEST
Match: SMESG000014290.1 (SMESG000014290.1)

HSP 1 Score: 328.946 bits (842), Expect = 4.803e-114
Identity = 169/206 (82.04%), Postives = 181/206 (87.86%), Query Frame = 3 
Query:   84 MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQKTSNCSC 701
            M SRKKILLK+IILGDSGVGKTSLMNQ+VN+KFTNQYKATIGADFLTKDV+VDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDV MP TF  LESWRDEFLIQS PRDP+ FPFVVIGNKVDL  R VA+RRAQQWCQSKGDI YFECSAK+A+NVEQAF  VARAALAQESE DI  +FPD+I+L   N   K + C C
Sbjct:    1 MASRKKILLKIIILGDSGVGKTSLMNQFVNRKFTNQYKATIGADFLTKDVMVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVAMPNTFKTLESWRDEFLIQSGPRDPEKFPFVVIGNKVDLESRAVAARRAQQWCQSKGDIPYFECSAKDAINVEQAFNAVARAALAQESEIDI--DFPDQIHLKAENCNTKQNGCGC 204
[Close]
BLAST of Ras-related protein Rab-7a vs. Planmine SMEST
Match: SMESG000075649.1 (SMESG000075649.1)

HSP 1 Score: 246.128 bits (627), Expect = 2.220e-81
Identity = 119/205 (58.05%), Postives = 149/205 (72.68%), Query Frame = 3 
Query:   90 SRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIAYFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDN-NREQKTSNCSC 701
            S+K  L K+IILGDSGVGKTSL+NQYVNK+F   YKATIG+DF  K+V +++ +VT+QIWDTAGQERFQSLG+AFYRGADCC+LVYDV+   TF NL SW++EF++Q++    + FPFVVIGNK+DL  R V  R AQQWC +  DIAYFE SAK+A+NV+ AF  +  A LA   E  I    P +I L +  N  +  S C C
Sbjct:    8 SKKNNLFKIIILGDSGVGKTSLLNQYVNKRFNTVYKATIGSDFQAKEVEINEHIVTLQIWDTAGQERFQSLGIAFYRGADCCILVYDVSRIDTFKNLNSWKEEFILQANLTAVEGFPFVVIGNKIDLDNRQVTLRTAQQWCLTNDDIAYFETSAKDAINVDNAF--IKAAQLAINHEVHISLPMPKQITLSNKPNETEDNSKCHC 210
[Close]
BLAST of Ras-related protein Rab-7a vs. Planmine SMEST
Match: SMESG000057972.1 (SMESG000057972.1)

HSP 1 Score: 140.969 bits (354), Expect = 5.328e-40
Identity = 67/142 (47.18%), Postives = 92/142 (64.79%), Query Frame = 3 
Query:  102 ILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDVIVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLESWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGD 527
            ILLKVI+LGD  VGK+SLM +YV   +      TIG +FL K+++V+ +   +QIWDTAGQE+++SL   FYRGAD CVL +   M  +F NL+ W  EFL + S ++   FPF+V GNK DL   N+  +   +WC S G+
Sbjct:    6 ILLKVILLGDCYVGKSSLMQRYVTNTYKEDNYHTIGVEFLRKEIVVNKQKYLLQIWDTAGQEKYRSLRTPFYRGADICVLTFSFDMVTSFENLDLWWQEFL-RYSGQENTKFPFIVFGNKCDLNIENIEEKMVLEWCSSHGE 146
The following BLAST results are available for this feature:
BLAST of Ras-related protein Rab-7a vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RAB7A3.619e-11775.85RAB7A, member RAS oncogene family [Source:HGNC Sym... [more]
RAB7A2.653e-9183.22RAB7A, member RAS oncogene family [Source:HGNC Sym... [more]
RAB7A1.897e-7959.90RAB7A, member RAS oncogene family [Source:HGNC Sym... [more]
RAB9A3.985e-6850.50RAB9A, member RAS oncogene family [Source:HGNC Sym... [more]
RAB9A3.985e-6850.50RAB9A, member RAS oncogene family [Source:HGNC Sym... [more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab-72.528e-10572.33RAB family [Source:UniProtKB/TrEMBL;Acc:Q23146][more]
rab-72.528e-10572.33RAB family [Source:UniProtKB/TrEMBL;Acc:Q23146][more]
rab-81.078e-3535.92RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5E... [more]
rab-81.078e-3535.92RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5E... [more]
unc-1083.780e-3539.36pep chromosome:WBcel235:I:3824947:3826514:1 gene:W... [more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rab73.938e-11776.33gene:FBgn0015795 transcript:FBtr0084503[more]
Rab73.938e-11776.33gene:FBgn0015795 transcript:FBtr0308612[more]
Rab73.938e-11776.33gene:FBgn0015795 transcript:FBtr0308611[more]
Rab95.674e-4345.45gene:FBgn0032782 transcript:FBtr0081206[more]
Rab354.277e-3637.06gene:FBgn0031090 transcript:FBtr0333549[more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab7a1.850e-11775.85RAB7a, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab7a1.850e-11775.85RAB7a, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab7a1.850e-11775.85RAB7a, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab7a1.850e-11775.85RAB7a, member RAS oncogene family [Source:ZFIN;Acc... [more]
zgc:1009181.185e-11375.24zgc:100918 [Source:ZFIN;Acc:ZDB-GENE-040927-2][more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab7a4.386e-11876.81RAB7A, member RAS oncogene family [Source:NCBI gen... [more]
rab7a1.020e-9772.28RAB7A, member RAS oncogene family [Source:NCBI gen... [more]
MGC758723.785e-7056.35uncharacterized protein mgc75872 [Source:NCBI gene... [more]
vasp7.780e-6750.24vasodilator stimulated phosphoprotein [Source:Xenb... [more]
rab9b3.118e-6654.19RAB9B, member RAS oncogene family [Source:NCBI gen... [more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rab72.485e-11775.85RAB7, member RAS oncogene family [Source:MGI Symbo... [more]
Rab72.485e-11775.85RAB7, member RAS oncogene family [Source:MGI Symbo... [more]
Rab72.485e-11775.85RAB7, member RAS oncogene family [Source:MGI Symbo... [more]
Rab72.485e-11775.85RAB7, member RAS oncogene family [Source:MGI Symbo... [more]
Rab72.485e-11775.85RAB7, member RAS oncogene family [Source:MGI Symbo... [more]
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BLAST of Ras-related protein Rab-7a vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P18067|RAB7A_CANLF1.701e-11675.85Ras-related protein Rab-7a OS=Canis lupus familiar... [more]
sp|P51150|RAB7A_MOUSE1.738e-11675.85Ras-related protein Rab-7a OS=Mus musculus OX=1009... [more]
sp|P51149|RAB7A_HUMAN1.738e-11675.85Ras-related protein Rab-7a OS=Homo sapiens OX=9606... [more]
sp|P09527|RAB7A_RAT2.071e-11675.85Ras-related protein Rab-7a OS=Rattus norvegicus OX... [more]
sp|H9BW96|RAB7_EPICO2.605e-11675.85Ras-related protein rab7 OS=Epinephelus coioides O... [more]
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BLAST of Ras-related protein Rab-7a vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3H7162.945e-11877.67ras-related protein Rab-7a OS=Lingula unguis OX=75... [more]
A0A212F3Y17.100e-11878.37Rab7 OS=Danaus plexippus plexippus OX=278856 GN=KG... [more]
A0A0L7LFE69.232e-11878.37Rab7 OS=Operophtera brumata OX=104452 GN=OBRU01_09... [more]
A0A2A4K0379.645e-11878.37Uncharacterized protein OS=Heliothis virescens OX=... [more]
R7V5G01.691e-11778.64Uncharacterized protein OS=Capitella teleta OX=283... [more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000041258.11.485e-11775.85RAB7A, member RAS oncogene family [Source:NCBI gen... [more]
rab7a1.568e-11775.85ras-related protein rab7 [Source:NCBI gene;Acc:103... [more]
rab7b3.343e-11374.76ras-related protein rab7-like [Source:NCBI gene;Ac... [more]
ENSAMXT00000002303.23.147e-10776.56RAB7A, member RAS oncogene family [Source:NCBI gen... [more]
ENSAMXT00000055036.13.147e-10776.56RAB7A, member RAS oncogene family [Source:NCBI gen... [more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab304.203e-3840.66RAB30, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab2a2.335e-3636.49RAB2A, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab8a1.075e-3535.32RAB8A, member RAS oncogene family [Source:ZFIN;Acc... [more]
RAB2B1.290e-3540.24RAB2B, member RAS oncogene family [Source:HGNC Sym... [more]
ENSPMAT00000000009.11.304e-3534.88pep scaffold:Pmarinus_7.0:GL476426:408368:444599:1... [more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
YPT74.321e-8459.53Rab family GTPase; GTP-binding protein of the rab ... [more]
VPS211.250e-3534.62Endosomal Rab family GTPase; required for endocyti... [more]
YPT62.112e-3532.54Rab family GTPase; required for endosome-to-Golgii... [more]
SEC44.550e-3438.82Rab family GTPase; essential for vesicle-mediated ... [more]
YPT16.308e-3333.33Rab family GTPase; involved in the ER-to-Golgi ste... [more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO453328.622e-11674.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO346955.886e-5954.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO421442.513e-3837.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO330744.044e-3842.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO474714.435e-3836.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ras-related protein Rab-7a vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab7a7.930e-11775.24ras-related protein rab7 [Source:NCBI gene;Acc:101... [more]
ENSORLT00000021125.24.593e-11574.88RAB7A, member RAS oncogene family [Source:NCBI gen... [more]
si:dkey-13a21.41.575e-6849.49ras-related protein rab7-like [Source:NCBI gene;Ac... [more]
rab9b9.850e-6649.50RAB9B, member RAS oncogene family [Source:ZFIN;Acc... [more]
si:dkey-13a21.41.228e-6554.22ras-related protein rab7-like [Source:NCBI gene;Ac... [more]
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BLAST of Ras-related protein Rab-7a vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000068863.15.252e-154100.00SMESG000068863.1[more]
SMESG000014290.14.316e-11582.13SMESG000014290.1[more]
SMESG000014290.14.803e-11482.04SMESG000014290.1[more]
SMESG000075649.12.220e-8158.05SMESG000075649.1[more]
SMESG000057972.15.328e-4047.18SMESG000057972.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005661 ID=SMED30005661|Name=Ras-related protein Rab-7a|organism=Schmidtea mediterranea sexual|type=transcript|length=977bp
TCTGTAGTTTTACTTCCACTATTACAGATTGACATCACTTTTTTTAGTCC
TGACAACTTTTCAATCAAAACTTAATCACTAAAATGACTTCTAGAAAGAA
AATCTTGTTAAAAGTTATTATTTTGGGTGACAGTGGTGTTGGAAAAACAT
CTTTGATGAATCAGTATGTTAATAAGAAATTCACCAATCAGTATAAAGCA
ACAATTGGAGCAGATTTTTTGACCAAAGATGTAATTGTTGACGACAGAGT
AGTGACTATGCAGATCTGGGACACTGCTGGCCAAGAAAGATTTCAGTCAC
TGGGAGTGGCGTTTTATCGTGGTGCCGATTGCTGTGTACTTGTTTATGAC
GTAACAATGCCTAAAACGTTTACAAATCTGGAGTCATGGAGGGATGAGTT
TTTGATTCAATCAAGTCCTCGTGATCCAGATCATTTTCCATTTGTTGTGA
TAGGAAACAAAGTCGATTTAGGAGAAAGAAATGTTGCATCTCGACGTGCC
CAACAATGGTGTCAGTCGAAAGGTGACATCGCATATTTCGAATGTAGTGC
AAAAGAAGCTTTAAACGTTGAGCAGGCTTTTCAGAATGTGGCTCGAGCCG
CACTCGCTCAGGAAAGTGAGGCAGACATAATCAATGAATTCCCAGACAAG
ATCAACCTGGGTGATAACAACCGGGAACAGAAGACCAGTAATTGTTCATG
TTGACAAATTGACAAATATCGACATTTCCACCGGATCCAGTGAAATGTTT
AACTGTTTTCGTTGTTTATTGATTATTCAATAATAAAATTTAATTTTTAA
TTGATCGAATTTATTTTTGAACATTTATTGAACATTTATTGTTCAAATTG
TAATTATCGATTTACTCAATTAATAATCCATTTATTGTATTTTATCGAAC
TTTCGGAATTTATTGATCATCATTGGATTATTTATCTGCCTGCCTGCCTA
CGTGTGTGTGTGTGTGTGTGTGTGTGT
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protein sequence of SMED30005661-orf-1

>SMED30005661-orf-1 ID=SMED30005661-orf-1|Name=SMED30005661-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=207bp
MTSRKKILLKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKDV
IVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLVYDVTMPKTFTNLE
SWRDEFLIQSSPRDPDHFPFVVIGNKVDLGERNVASRRAQQWCQSKGDIA
YFECSAKEALNVEQAFQNVARAALAQESEADIINEFPDKINLGDNNREQK
TSNCSC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000499cell
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR027417P-loop_NTPase
IPR001806Small_GTPase
Vocabulary: molecular function
TermDefinition
GO:0005525GTP binding
GO:0019003GDP binding
GO:1905394retromer complex binding
GO:0000166nucleotide binding
GO:0003924GTPase activity
GO:0005515protein binding
Vocabulary: biological process
TermDefinition
GO:0007264small GTPase mediated signal transduction
GO:0016042lipid catabolic process
GO:0019076viral release from host cell
GO:0022615protein to membrane docking
GO:0042147retrograde transport, endosome to Golgi
GO:0045022early endosome to late endosome transport
GO:0045732positive regulation of protein catabolic process
GO:0048524positive regulation of viral process
GO:0061724lipophagy
GO:0090383phagosome acidification
GO:0090385phagosome-lysosome fusion
GO:1903542negative regulation of exosomal secretion
GO:1903543positive regulation of exosomal secretion
GO:2000785regulation of autophagosome assembly
GO:0006622protein targeting to lysosome
GO:0006629lipid metabolic process
GO:0006810transport
GO:0006886intracellular protein transport
GO:0006914autophagy
GO:0007174epidermal growth factor catabolic process
GO:0008333endosome to lysosome transport
GO:0015031protein transport
Vocabulary: cellular component
TermDefinition
GO:0030670phagocytic vesicle membrane
GO:0030904retromer complex
GO:0031410cytoplasmic vesicle
GO:0031902late endosome membrane
GO:0032419extrinsic component of lysosome membrane
GO:0033162melanosome membrane
GO:0034045pre-autophagosomal structure membrane
GO:0045335phagocytic vesicle
GO:0070062extracellular exosome
GO:0000421autophagosome membrane
GO:0005737cytoplasm
GO:0005764lysosome
GO:0005765lysosomal membrane
GO:0005768endosome
GO:0005770late endosome
GO:0005794Golgi apparatus
GO:0005811lipid particle
GO:0005829cytosol
GO:0010008endosome membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 9..30
score: 44.25
coord: 116..129
score: 43.0
coord: 32..48
score: 35.95
coord: 151..173
score: 41.61
coord: 50..72
score: 48.77
NoneNo IPR availableSMARTSM00176ran_sub_2coord: 14..200
e-value: 2.3E-9
score: 47.1
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 6..176
e-value: 1.3E-27
score: 107.8
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 9..176
e-value: 4.2E-90
score: 315.3
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 11..176
e-value: 3.4E-14
score: 61.3
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 1..190
e-value: 6.4E-68
score: 229.7
NoneNo IPR availablePANTHERPTHR24073:SF556RAS-RELATED PROTEIN RAB-7Acoord: 6..206
NoneNo IPR availablePANTHERPTHR24073FAMILY NOT NAMEDcoord: 6..206
NoneNo IPR availablePROSITEPS51419RABcoord: 3..206
score: 31.69
NoneNo IPR availableCDDcd01862Rab7coord: 9..179
e-value: 8.59156E-132
score: 365.449
IPR001806Small GTPasePFAMPF00071Rascoord: 10..173
e-value: 3.4E-57
score: 192.6
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 9..169
e-value: 8.8E-24
score: 82.1
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 9..173