slc39a-12

Overview


Name	slc39a-12 (AKN21677.1)
Smed ID	SMED30005645
Length (bp)	1694

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of slc39a-12 (SMED30005645) t-SNE clustered cells

Violin plots show distribution of expression levels for slc39a-12 (SMED30005645) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc39a-12 (SMED30005645) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc39a-12 (SMED30005645) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30005645

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
parapharyngeal region	SMED30005645	SMESG000016243.1	dd_Smed_v4_8605_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30005645	SMESG000016243.1	dd_Smed_v4_8605_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
reproductive organ	SMED30005645	SMESG000016243.1	Contig3329	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30005645	SMESG000016243.1	Contig3329	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30005645	SMESG000061388.1	Contig3329	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30005645	SMESG000061388.1	Contig3329	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of slc39a-12 vs. Ensembl Human
Match: SLC39A14 (solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858])

HSP 1 Score: 201.06 bits (510), Expect = 2.052e-57
Identity = 114/301 (37.87%), Postives = 176/301 (58.47%), Query Frame = 1

Query:  658 SSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXX-----XXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            S++++W YG + VT+I+ C+ LG   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  +  +  SL   +  +  +     N D   ++     + L+             +  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI++
Sbjct:  149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYISL 441

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BLAST of slc39a-12 vs. Ensembl Human
Match: SLC39A14 (solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858])

HSP 1 Score: 200.675 bits (509), Expect = 3.110e-57
Identity = 114/301 (37.87%), Postives = 175/301 (58.14%), Query Frame = 1

Query:  658 SSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTL-----XXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            S++++W YG + VT+I+ C+ LG   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  +  +  SL   +  +  +     N D   ++     + L              +  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI++
Sbjct:  149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYISL 441

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Query:  658 SSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTL-----XXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            S++++W YG + VT+I+ C+ LG   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  +  +  SL   +  +  +     N D   ++     + L              +  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI++
Sbjct:  149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYISL 441

[Close]

BLAST of slc39a-12 vs. Ensembl Human
Match: SLC39A14 (solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858])

HSP 1 Score: 196.823 bits (499), Expect = 9.893e-56
Identity = 111/301 (36.88%), Postives = 177/301 (58.80%), Query Frame = 1

Query:  658 SSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTL-----XXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            S++++W +GF+SV++IN  + LG+L +P   K F+  ++T+ I+L++G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  +  +  SL   +  +  +     N D   ++     + L              +  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI++
Sbjct:  149 SAVEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEAF-------GFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYISL 441

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BLAST of slc39a-12 vs. Ensembl Human
Match: SLC39A8 (solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862])

HSP 1 Score: 176.022 bits (445), Expect = 2.750e-48
Identity = 123/343 (35.86%), Postives = 192/343 (55.98%), Query Frame = 1

Query:  526 FVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNI---SRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            F N+T ++  S F  +   ++ ++    C     + P H K   S  ++W YGF+SVTIIN  + LG++  PL+ K ++  ++TF + LA+G+L  +A+  LIP+A        G+     SY  KA  VFGG Y+ F  ER LK ++    +T+ +      G+ N     +T +PK  +  IN        P +     +   +  +   + +     +    +K  K   +  +AWMI   DALHNFIDGL+IGA+ + + + G+S SIA++CEE PHELGDF ILLNAGM+ +QAL++N LSA +CY+G   G+++G   +    +FA+AGGMFLYI++
Sbjct:   86 FSNAT-QITSSKFSVICPAVLQQLNFHPCE----DRPKH-KTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-------GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLL----KTYGQNGHTHFGNDNFGPQEKTHQPK-ALPAINGVT-CYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFA-PNIIFALAGGMFLYISL 408

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BLAST of slc39a-12 vs. Ensembl Celegans
Match: zipt-15 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:U4PS08])

HSP 1 Score: 180.644 bits (457), Expect = 6.542e-51
Identity = 119/315 (37.78%), Postives = 179/315 (56.83%), Query Frame = 1

Query:  670 MWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQ--LAEL-QHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINS----DNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNST---------------DXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGE-TTSGSTWVFAVAGGMFLYINV 1545
            +W  G + VT+IN CA +GI  +  + K  Y  ++T  + L VGSL+GS+   L+P A    + E+ ++G P +  SY + A +   GVY FF  ++ +K I+  E+R  N+   + H  L+I     P +  ++ +S    D        +++ L     +K + +E   + L                  D           +A VAWMI+FGD LHNFIDG+SIGAAF+ +  +G+S+S+AV+CEE PHELGD AIL+ +GM +KQAL++N+LSA TCY+GF IGV +GE     S + F +AGGMFLYI++
Sbjct:   56 VWGVGLLFVTLINMCAVVGIGVMRYLTKNTYNQIITLFVGLGVGSLSGSSFYHLLPQAHPSLMDEVDENGVPTH--SYLHMAHISILGVYAFFFCDKLIKIIL--EIRKKNQ--HIHHRRLSIE---NPGMTTERSDSTFVTDAGDREEELLRSVLKKGVMSKADIDETEMMTLEDKSGKSMGDQAHGICVHDHSIEFRAGDSAIAAVAWMIVFGDGLHNFIDGISIGAAFAESLHSGLSISLAVLCEEFPHELGDVAILVASGMTLKQALIYNLLSAITCYVGFFIGVGIGELGPDTSKYAFGLAGGMFLYISL 361

[Close]

BLAST of slc39a-12 vs. Ensembl Celegans
Match: zipt-15 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:U4PS08])

HSP 1 Score: 147.132 bits (370), Expect = 8.738e-40
Identity = 95/248 (38.31%), Postives = 141/248 (56.85%), Query Frame = 1

Query:  862 QHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINS----DNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNST---------------DXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGE-TTSGSTWVFAVAGGMFLYINV 1545
            ++G P +  SY + A +   GVY FF  ++ +K I+  E+R  N+   + H  L+I     P +  ++ +S    D        +++ L     +K + +E   + L                  D           +A VAWMI+FGD LHNFIDG+SIGAAF+ +  +G+S+S+AV+CEE PHELGD AIL+ +GM +KQAL++N+LSA TCY+GF IGV +GE     S + F +AGGMFLYI++
Sbjct:    6 ENGVPTH--SYLHMAHISILGVYAFFFCDKLIKIIL--EIRKKNQ--HIHHRRLSIE---NPGMTTERSDSTFVTDAGDREEELLRSVLKKGVMSKADIDETEMMTLEDKSGKSMGDQAHGICVHDHSIEFRAGDSAIAAVAWMIVFGDGLHNFIDGISIGAAFAESLHSGLSISLAVLCEEFPHELGDVAILVASGMTLKQALIYNLLSAITCYVGFFIGVGIGELGPDTSKYAFGLAGGMFLYISL 244

[Close]

BLAST of slc39a-12 vs. Ensembl Celegans
Match: zipt-17 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:Q9XVR4])

HSP 1 Score: 103.99 bits (258), Expect = 7.070e-24
Identity = 47/102 (46.08%), Postives = 71/102 (69.61%), Query Frame = 1

Query: 1234 MIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            +I+FGD +HN +DGL++GA+F  +   G   +IAVIC ELPHE+GD A+L+++G+++  AL+ N+LSA T Y G  I ++LG      T + A+  GMFLY+
Sbjct:  236 IILFGDGVHNLVDGLAMGASFMISVKLGFITTIAVICHELPHEIGDLAVLIDSGLSMCTALILNLLSALTAYAGLFIAIVLGRDEEIETILLAITAGMFLYV 337

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BLAST of slc39a-12 vs. Ensembl Celegans
Match: zipt-16 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:Q8I4G0])

HSP 1 Score: 104.76 bits (260), Expect = 1.313e-23
Identity = 47/104 (45.19%), Postives = 75/104 (72.12%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGET-TSGSTWVFAVAGGMFLYI 1539
            +MIIFG + +NF+DG+S+GAAFS N + G+S+ IAVI ++ P ELG  AIL+ +G+ +K+ L++NM+     ++GF IGV+L     S   ++FA++ GM++YI
Sbjct:  356 YMIIFGSSANNFVDGMSMGAAFSDNLLRGLSIGIAVISQQFPQELGTLAILVKSGLGLKKTLLFNMVPIVLSFLGFSIGVMLDSVDDSYDEYIFAISSGMYMYI 459

HSP 2 Score: 72.7886 bits (177), Expect = 2.621e-13
Identity = 44/150 (29.33%), Postives = 77/150 (51.33%), Query Frame = 1

Query:  667 KMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSL--NISRTPKPKLEIDQINSDNHLIVAPEMKT 1110
            + W  GF  V+  +  A LGIL +P ++K  Y+ +MTF++++ +G+L+GS + I++P A  L   +H        Y  K+ ++   +Y FF ++R L++I+  E R   +     H S   ++  TP  K   +  N+    IV  E  T
Sbjct:   48 QTWGIGFAIVSGCSFSAPLGILLLPCLSKSLYERIMTFLVAVGIGALSGSTIFIMLPQAFHLTSFEH------FEYHTKSLIILCALYAFFTVDRMLQYIL--EFRRRRQTKRRIHASTIASLMNTPTTKRRDNGHNTTEETIVPSEPPT 189

[Close]

BLAST of slc39a-12 vs. Ensembl Celegans
Match: zipt-16 (Zrt (ZRT), Irt-(IRT-) like Protein Transporter [Source:UniProtKB/TrEMBL;Acc:Q8I4G0])

HSP 1 Score: 104.375 bits (259), Expect = 1.468e-23
Identity = 47/104 (45.19%), Postives = 75/104 (72.12%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGET-TSGSTWVFAVAGGMFLYI 1539
            +MIIFG + +NF+DG+S+GAAFS N + G+S+ IAVI ++ P ELG  AIL+ +G+ +K+ L++NM+     ++GF IGV+L     S   ++FA++ GM++YI
Sbjct:  349 YMIIFGSSANNFVDGMSMGAAFSDNLLRGLSIGIAVISQQFPQELGTLAILVKSGLGLKKTLLFNMVPIVLSFLGFSIGVMLDSVDDSYDEYIFAISSGMYMYI 452

HSP 2 Score: 72.7886 bits (177), Expect = 2.645e-13
Identity = 44/150 (29.33%), Postives = 77/150 (51.33%), Query Frame = 1

Query:  667 KMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSL--NISRTPKPKLEIDQINSDNHLIVAPEMKT 1110
            + W  GF  V+  +  A LGIL +P ++K  Y+ +MTF++++ +G+L+GS + I++P A  L   +H        Y  K+ ++   +Y FF ++R L++I+  E R   +     H S   ++  TP  K   +  N+    IV  E  T
Sbjct:   41 QTWGIGFAIVSGCSFSAPLGILLLPCLSKSLYERIMTFLVAVGIGALSGSTIFIMLPQAFHLTSFEH------FEYHTKSLIILCALYAFFTVDRMLQYIL--EFRRRRQTKRRIHASTIASLMNTPTTKRRDNGHNTTEETIVPSEPPT 182

[Close]

BLAST of slc39a-12 vs. Ensembl Fly
Match: foi (gene:FBgn0024236 transcript:FBtr0331418)

HSP 1 Score: 130.954 bits (328), Expect = 1.367e-32
Identity = 57/103 (55.34%), Postives = 76/103 (73.79%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            WMII GD LHNF DG++IGAAF+ N   G S S+AV C ELPHELGDFAIL+ AGM++K A+ +N+L+    +IG I G+  G++   + W+FAVA G+F+YI
Sbjct:  545 WMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYI 647

HSP 2 Score: 28.8758 bits (63), Expect = 1.367e-32
Identity = 14/27 (51.85%), Postives = 21/27 (77.78%), Query Frame = 2

Query: 1613 FIIQNIGLLMGYSILLLMALY-GDKIS 1690
            F++Q +G+L G  I+LL+ALY GD +S
Sbjct:  666 FLLQILGMLSGVGIMLLIALYEGDLMS 692

HSP 3 Score: 62.3882 bits (150), Expect = 7.627e-10
Identity = 34/117 (29.06%), Postives = 60/117 (51.28%), Query Frame = 1

Query:  670 MWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFL-------KWIINKEVRTFNRA 999
            +W+Y FISV        +G+  IP M  ++YK ++ ++++LAVG++TG ALL L+P ++   +        +     K     GG+  F+++E  L       K +  KE +  +RA
Sbjct:  260 VWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQD--------ERGMIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRA 368

[Close]

BLAST of slc39a-12 vs. Ensembl Fly
Match: foi (gene:FBgn0024236 transcript:FBtr0345601)

HSP 1 Score: 130.954 bits (328), Expect = 1.367e-32
Identity = 57/103 (55.34%), Postives = 76/103 (73.79%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            WMII GD LHNF DG++IGAAF+ N   G S S+AV C ELPHELGDFAIL+ AGM++K A+ +N+L+    +IG I G+  G++   + W+FAVA G+F+YI
Sbjct:  545 WMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYI 647

HSP 2 Score: 28.8758 bits (63), Expect = 1.367e-32
Identity = 14/27 (51.85%), Postives = 21/27 (77.78%), Query Frame = 2

Query: 1613 FIIQNIGLLMGYSILLLMALY-GDKIS 1690
            F++Q +G+L G  I+LL+ALY GD +S
Sbjct:  666 FLLQILGMLSGVGIMLLIALYEGDLMS 692

HSP 3 Score: 62.3882 bits (150), Expect = 7.627e-10
Identity = 34/117 (29.06%), Postives = 60/117 (51.28%), Query Frame = 1

Query:  670 MWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFL-------KWIINKEVRTFNRA 999
            +W+Y FISV        +G+  IP M  ++YK ++ ++++LAVG++TG ALL L+P ++   +        +     K     GG+  F+++E  L       K +  KE +  +RA
Sbjct:  260 VWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQD--------ERGMIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRA 368

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BLAST of slc39a-12 vs. Ensembl Fly
Match: foi (gene:FBgn0024236 transcript:FBtr0331417)

HSP 1 Score: 130.954 bits (328), Expect = 1.367e-32
Identity = 57/103 (55.34%), Postives = 76/103 (73.79%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            WMII GD LHNF DG++IGAAF+ N   G S S+AV C ELPHELGDFAIL+ AGM++K A+ +N+L+    +IG I G+  G++   + W+FAVA G+F+YI
Sbjct:  545 WMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYI 647

HSP 2 Score: 28.8758 bits (63), Expect = 1.367e-32
Identity = 14/27 (51.85%), Postives = 21/27 (77.78%), Query Frame = 2

Query: 1613 FIIQNIGLLMGYSILLLMALY-GDKIS 1690
            F++Q +G+L G  I+LL+ALY GD +S
Sbjct:  666 FLLQILGMLSGVGIMLLIALYEGDLMS 692

HSP 3 Score: 62.3882 bits (150), Expect = 7.627e-10
Identity = 34/117 (29.06%), Postives = 60/117 (51.28%), Query Frame = 1

Query:  670 MWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFL-------KWIINKEVRTFNRA 999
            +W+Y FISV        +G+  IP M  ++YK ++ ++++LAVG++TG ALL L+P ++   +        +     K     GG+  F+++E  L       K +  KE +  +RA
Sbjct:  260 VWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQD--------ERGMIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRA 368

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BLAST of slc39a-12 vs. Ensembl Fly
Match: foi (gene:FBgn0024236 transcript:FBtr0076624)

HSP 1 Score: 130.954 bits (328), Expect = 1.367e-32
Identity = 57/103 (55.34%), Postives = 76/103 (73.79%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            WMII GD LHNF DG++IGAAF+ N   G S S+AV C ELPHELGDFAIL+ AGM++K A+ +N+L+    +IG I G+  G++   + W+FAVA G+F+YI
Sbjct:  545 WMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYI 647

HSP 2 Score: 28.8758 bits (63), Expect = 1.367e-32
Identity = 14/27 (51.85%), Postives = 21/27 (77.78%), Query Frame = 2

Query: 1613 FIIQNIGLLMGYSILLLMALY-GDKIS 1690
            F++Q +G+L G  I+LL+ALY GD +S
Sbjct:  666 FLLQILGMLSGVGIMLLIALYEGDLMS 692

HSP 3 Score: 62.3882 bits (150), Expect = 7.627e-10
Identity = 34/117 (29.06%), Postives = 60/117 (51.28%), Query Frame = 1

Query:  670 MWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFL-------KWIINKEVRTFNRA 999
            +W+Y FISV        +G+  IP M  ++YK ++ ++++LAVG++TG ALL L+P ++   +        +     K     GG+  F+++E  L       K +  KE +  +RA
Sbjct:  260 VWIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQD--------ERGMIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKPSRA 368

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BLAST of slc39a-12 vs. Ensembl Fly
Match: Zip71B (gene:FBgn0036461 transcript:FBtr0113171)

HSP 1 Score: 108.227 bits (269), Expect = 1.733e-24
Identity = 47/104 (45.19%), Postives = 73/104 (70.19%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGST-WVFAVAGGMFLYI 1539
            +M+I GD LHN  DGL+IGAAF+ + +TG + + AV+C ELPHELGDFA+LL  G+++++A+  N++S+   ++G  +G+ +     G T W++A   G FLYI
Sbjct:  414 FMVIIGDGLHNLTDGLAIGAAFASDPVTGFATAFAVLCHELPHELGDFALLLQTGVSMRRAVYMNIVSSVLSFVGMSVGLFIAGIGDGMTQWIYAATAGSFLYI 517

HSP 2 Score: 65.4698 bits (158), Expect = 6.348e-11
Identity = 48/159 (30.19%), Postives = 80/159 (50.31%), Query Frame = 1

Query:  385 CFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKAN--FSTECLARRFVNS---TPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAM 846
            C S  S  + +    +L  N + +    L+KN +S  +   ++E     F+NS   TP         L+A I + V    C    + S + +  N      W+Y  I++ I++AC  LGIL +PLM    Y+ ++ F++S+AVG+L G AL+ L+P A+
Sbjct:  148 CLSPKSLLSLIVNHNDLHKNIAYRKL--LIKNDVSSTDGVHNSEEEYNEFINSVRITPRAFMKLCPALLAQIDNGV----CKQPAVRSVNLNDKNQKIWYAWIYASITMLILSACGLLGILLVPLMKSAAYQEILKFLVSIAVGTLAGDALMHLLPHAL 300

[Close]

BLAST of slc39a-12 vs. Ensembl Zebrafish
Match: slc39a14 (solute carrier family 39 member 14 [Source:NCBI gene;Acc:799782])

HSP 1 Score: 193.356 bits (490), Expect = 1.238e-54
Identity = 120/382 (31.41%), Postives = 192/382 (50.26%), Query Frame = 1

Query:  475 KNKLSKANFSTECLARRFV-----NSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKE-------------VRTFNRANS---------LSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            K + ++ N +++CLA   +     +    + +   + +   ++ ++    C   + N  S S    +  ++W YG + VT+I+ C+ +G   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK I+  +                +  +N          L +G    +  P+ + +   +  D+ ++   +      +           ++    S             +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S   W+FA+AGGMFLYI
Sbjct:   80 KTQPTRTN-ASKCLAADTLAVYGMSEQSRIDERGLQQICPTMIQQLDSQACKT-QPNQESESSPRPTEAEVWGYGLLCVTVISLCSLVGASVVPFMRKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFDPMEDYYVPKSAVVFGGFYLFFFTEKILKMILKPKDTGGHGHGHSHFPAERYANSNGDLEDGVMEKLQNGEAGGAALPRAEADGRGVGEDDKMLSTGQTVQDTQSSGGGGTGGCYWLKGRAYSD------------IGTLAWMITLSDGLHNFIDGLAIGASFTASVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGMGFGILAGNNFS-PNWIFALAGGMFLYI 439

[Close]

Query:  475 KNKLSKANFSTECLARRFV-----NSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKE-------------VRTFNRANS---------LSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            K + ++ N +++CLA   +     +    + +   + +   ++ ++    C   + N  S S    +  ++W YG + VT+I+ C+ +G   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK I+  +                +  +N          L +G    +  P+ + +   +  D+ ++   +      +           ++    S             +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S   W+FA+AGGMFLYI
Sbjct:   80 KTQPTRTN-ASKCLAADTLAVYGMSEQSRIDERGLQQICPTMIQQLDSQACKT-QPNQESESSPRPTEAEVWGYGLLCVTVISLCSLVGASVVPFMRKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFDPMEDYYVPKSAVVFGGFYLFFFTEKILKMILKPKDTGGHGHGHSHFPAERYANSNGDLEDGVMEKLQNGEAGGAALPRAEADGRGVGEDDKMLSTGQTVQDTQSSGGGGTGGCYWLKGRAYSD------------IGTLAWMITLSDGLHNFIDGLAIGASFTASVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGMGFGILAGNNFS-PNWIFALAGGMFLYI 439

[Close]

BLAST of slc39a-12 vs. Ensembl Zebrafish
Match: slc39a14 (solute carrier family 39 member 14 [Source:NCBI gene;Acc:799782])

HSP 1 Score: 186.037 bits (471), Expect = 5.556e-52
Identity = 115/382 (30.10%), Postives = 193/382 (50.52%), Query Frame = 1

Query:  475 KNKLSKANFSTECLARRFV-----NSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKE-------------VRTFNRANS---------LSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            K + ++ N +++CLA   +     +    + +   + +   ++ ++    C   + N  S S    +  ++W Y  +SVT+++A A  G+  +PLM  +F + ++ + I+L++G+L  +A+L L+P+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK I+  +                +  +N          L +G    +  P+ + +   +  D+ ++   +      +           ++    S             +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S   W+FA+AGGMFLYI
Sbjct:   80 KTQPTRTN-ASKCLAADTLAVYGMSEQSRIDERGLQQICPTMIQQLDSQACKT-QPNQESESSPRPTEAEVWGYSILSVTLVSAFALTGVFVVPLMRTRFMRRVLVYFIALSIGTLLSTAILQLLPEAF-------GFDPMEDYYVPKSAVVFGGFYLFFFTEKILKMILKPKDTGGHGHGHSHFPAERYANSNGDLEDGVMEKLQNGEAGGAALPRAEADGRGVGEDDKMLSTGQTVQDTQSSGGGGTGGCYWLKGRAYSD------------IGTLAWMITLSDGLHNFIDGLAIGASFTASVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGMGFGILAGNNFS-PNWIFALAGGMFLYI 439

[Close]

BLAST of slc39a-12 vs. Ensembl Zebrafish
Match: LO018202.1 (pep chromosome:GRCz11:14:50034196:50059783:1 gene:ENSDARG00000113547.1 transcript:ENSDART00000190301.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LO018202.1)

HSP 1 Score: 170.244 bits (430), Expect = 6.792e-47
Identity = 113/347 (32.56%), Postives = 183/347 (52.74%), Query Frame = 1

Query:  502 STECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEV-RTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            + E L     ++T  L +     +   +++K ++P C     + P+H++   S L +W Y F++VTIIN  + LG+  +P+  K F+  ++T+ + L VG+L  +  L LIP+A        G+      +  ++  VFGG Y  +++E+ LK ++  E  +  N+  S   G  N   T     EI+   SD  + +A E  +   +    +         NL++                  WMI   DA++NFIDG++IGA+FS + + G S SIA   EELPHELGDF ILLNAG+++ QA  +N+LS+ +CY G ++G++LG T S    +FA++ GMF YI
Sbjct:   74 AEEILVHYGFHNTSVLNEEHLSIVCPALLNKAVLPPC---PTDPPTHTED--SDLHVWGYAFLAVTIINLASLLGMTLVPITKKPFFPKVLTYFLGLGVGTLFSNGALQLIPEAF-------GFDPKADGFVLQSVGVFGGFYALYIVEKILKIVLKPEYEQGHNQCQSSECGQQNPGFTDS---EINLAISDK-ISIASEPASERGSCKWLRGR-------NLSNVKTVA-------------WMISLSDAINNFIDGITIGASFSVSLVNGFSTSIACASEELPHELGDFIILLNAGLSVPQAAFFNLLSSCSCYFGLVVGILLGNTFS-PGLIFALSSGMFFYI 383

[Close]

BLAST of slc39a-12 vs. Ensembl Zebrafish
Match: slc39a10 (solute carrier family 39 member 10 [Source:NCBI gene;Acc:393644])

HSP 1 Score: 140.198 bits (352), Expect = 9.841e-37
Identity = 62/104 (59.62%), Postives = 80/104 (76.92%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSG-STWVFAVAGGMFLYI 1539
            WM+I GD +HNF DGL+IGAAFS N   GIS S+AV C ELPHELGDFA+LL AGM++KQA+++N+LSA   Y G +IG  +G+ T   ++W+FAV  GMFLY+
Sbjct:  689 WMVIMGDGMHNFSDGLAIGAAFSANITGGISTSVAVFCHELPHELGDFAVLLKAGMSVKQAIVYNLLSALMAYAGMVIGTAVGQYTHNVTSWIFAVTAGMFLYV 792

HSP 2 Score: 33.8834 bits (76), Expect = 9.841e-37
Identity = 12/25 (48.00%), Postives = 20/25 (80.00%), Query Frame = 2

Query: 1613 FIIQNIGLLMGYSILLLMALYGDKI 1687
            F++QN G+L G+ I+LL+A++ D I
Sbjct:  817 FVLQNFGMLTGFGIMLLIAIFEDHI 841

HSP 3 Score: 64.3142 bits (155), Expect = 2.790e-10
Identity = 37/107 (34.58%), Postives = 65/107 (60.75%), Query Frame = 1

Query:  658 SSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHG-----YPGYQVSYKY----KATVVFGGVYMFFLLER 951
            SS  +W++GF+S+TII+  + LG++ +P++N+  +K L+TF+++LAVG+L+G ALL L+P +    +  HG      P      K+    K      G+Y+ F++E 
Sbjct:  438 SSGWVWMWGFVSITIISLLSLLGVVLVPILNQSCFKFLLTFLVALAVGTLSGDALLHLLPHSQGDHDHNHGEQMEEEPEVDFLIKFDGVWKGLTALAGIYLLFIIEH 544

[Close]

BLAST of slc39a-12 vs. Ensembl Xenopus
Match: slc8a2 (solute carrier family 8 member A2 [Source:Xenbase;Acc:XB-GENE-992835])

HSP 1 Score: 202.216 bits (513), Expect = 6.170e-58
Identity = 129/375 (34.40%), Postives = 201/375 (53.60%), Query Frame = 1

Query:  430 NLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCN---IIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQI-NSD-NHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            +L  N  +   G   +N +S+   S+   A   + S   +    F+     I+ ++    C      +  +   ++   S  ++W YGF+ VT+I+ C+  G   +P M K  YK L+ F I+LA+G+L  +AL  LIP+A        G+   + SY + ++V+FGG Y+FF  E+ LK ++ ++       +  SH S + S+    +   +++ N D +H+I  P    +            +  +L    +    +K I+   +  +AWMI   D LHNFIDGL+IGA+F+ +   G+S SIA++CEE PHELGDF ILLNAGM+I QAL +N LSA  CY+G   G++ G   S S W+FA+AGGMFLYI
Sbjct:   60 SLLENLEVGKGGGNQRN-MSQCLSSSTLFAAHNLTSGSVVDAEGFQSFCPTILQQLETRACQESPAFQNETTPGAEGRPSPGEVWGYGFLCVTVISLCSLFGAGVVPFMKKACYKRLLLFCIALAIGTLFSNALFQLIPEAF-------GFNPLEDSYVFTSSVIFGGFYLFFFTEKVLKMMLKQK-----HEHGHSHYSADTSKRDAEEGVTEKLQNGDLDHMIPPPHGSES---DLRGDEKAVQQQDLPGQQSSCYWLKGIRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGVSTSIAILCEEFPHELGDFVILLNAGMSIPQALFFNFLSACCCYLGLAFGILAGSHFS-SNWIFALAGGMFLYI 417

[Close]

BLAST of slc39a-12 vs. Ensembl Xenopus
Match: slc8a2 (solute carrier family 8 member A2 [Source:Xenbase;Acc:XB-GENE-992835])

HSP 1 Score: 201.83 bits (512), Expect = 7.058e-58
Identity = 126/375 (33.60%), Postives = 205/375 (54.67%), Query Frame = 1

Query:  430 NLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCN---IIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQI-NSD-NHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            +L  N  +   G   +N +S+   S+   A   + S   +    F+     I+ ++    C      +  +   ++   S  ++W YG ++VT+I+  + LG+ F P + + F++ L+T+ I+L++G+L  +ALL LIP+A        G+   + SY + ++V+FGG Y+FF  E+ LK ++ ++       +  SH S + S+    +   +++ N D +H+I  P    +            +  +L    +    +K I+   +  +AWMI   D LHNFIDGL+IGA+F+ +   G+S SIA++CEE PHELGDF ILLNAGM+I QAL +N LSA  CY+G   G++ G   S S W+FA+AGGMFLYI
Sbjct:   60 SLLENLEVGKGGGNQRN-MSQCLSSSTLFAAHNLTSGSVVDAEGFQSFCPTILQQLETRACQESPAFQNETTPGAEGRPSPGEVWGYGLLAVTVISLASLLGVFFAPCVKRPFFRRLLTYFIALSIGTLLSNALLQLIPEAF-------GFNPLEDSYVFTSSVIFGGFYLFFFTEKVLKMMLKQK-----HEHGHSHYSADTSKRDAEEGVTEKLQNGDLDHMIPPPHGSES---DLRGDEKAVQQQDLPGQQSSCYWLKGIRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGVSTSIAILCEEFPHELGDFVILLNAGMSIPQALFFNFLSACCCYLGLAFGILAGSHFS-SNWIFALAGGMFLYI 417

[Close]

BLAST of slc39a-12 vs. Ensembl Xenopus
Match: SLC39A8 (solute carrier family 39 (zinc transporter), member 8 [Source:NCBI gene;Acc:100487145])

HSP 1 Score: 196.438 bits (498), Expect = 7.008e-56
Identity = 126/361 (34.90%), Postives = 188/361 (52.08%), Query Frame = 1

Query:  502 STECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIIN---KEVRTFNRANSLSHGSLNISRTPKPKLE----------IDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            STE +   +     ++   TFE     I+ ++    C      S   S    S  ++W + F+SVTIIN  + LG+   PL+ K ++  ++T+ + LA+G+L  +A+  LIP+A        G+     +Y  KA  +FGG Y+   +ER LK I+N   + V T    + + H  L+I  +P  K+           + +IN  NHL     +K +  +          +    L S                  WMI   DALHNFIDGL+IGA+F+ + + G+S SIA++CEE PHE GDFAIL+NAGM+I QAL +N LSA +CYIG + G+++G     S  +FA+AGGMFLYI +
Sbjct:   75 STEDIFSIYNIKNDQITNVTFETFCPAILHQIFFHPCT---FESQDESTQRPSPAQVWGFSFLSVTIINLTSLLGLFITPLIKKPYFPKILTYFVGLAIGTLFSNAIFQLIPEAF-------GFDPKVDNYVPKAVAIFGGFYILLFVERLLKLILNIYGEGVHTHLEIDHVPHQELHI-ESPANKIPNGNIIYSNPAVAEINGVNHL---DNIKVSSKDAVEEVYCCKVLKWRPLKSIGTLA-------------WMITLSDALHNFIDGLAIGASFTLSVLQGLSTSIAILCEEFPHEFGDFAILINAGMSIPQALTFNFLSACSCYIGLVFGILVGNNFEPSI-IFAIAGGMFLYIGL 407

[Close]

BLAST of slc39a-12 vs. Ensembl Xenopus
Match: tmem135 (transmembrane protein 135 [Source:Xenbase;Acc:XB-GENE-954105])

HSP 1 Score: 160.999 bits (406), Expect = 3.608e-42
Identity = 102/351 (29.06%), Postives = 177/351 (50.43%), Query Frame = 1

Query:  538 TPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQ-LAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVI-----ELNLNSTDXXXXXXXXXXXXXXX----------XWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGST-WVFAVAGGMFLYI 1539
            TP+        L+  I  +V I H + +  NS   SK  L  L++  +G ++VT+I+A + L + F+PL+ +  ++ L+ F+++LAVG+L G ALL L+P A +     QHG   + +    K   V GG+Y+ FL+E  +  +  ++                + R  KP++       +++     ++ + + +         E++     E+ +   D                          WM++ GD +HNF DGL+IGAAFS     G+S ++AV C ELPHELGDFA+LL +G+ +++ L ++++SA   + G IIG +  + ++  T W+FA   G+FLY+
Sbjct:  196 TPQQFSLLCPALLYQIDSRVCIHHSDELT-NSKPDSKQAL--LQVLGWGALAVTVISAPSLLAVAFVPLLRRPLFRYLLRFLVALAVGTLCGDALLHLMPHAQEDHTGNQHGGKTHAIEPVLKGLSVLGGLYLLFLIENLMGLLKQRQ---------------QLKRLSKPEVPA---GDESYTTALWDLGSPVESEFCEVSRAAEILQRGNEEVEIRRRDEKDAPAPHSHSGHSHNMASKGITEIVWMVLLGDGIHNFTDGLAIGAAFSSGFSGGLSTTVAVFCHELPHELGDFAVLLQSGVPVRKVLFFSLVSAFLSFFGMIIGAVASQNSAQITPWIFAATAGIFLYV 525

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BLAST of slc39a-12 vs. Ensembl Xenopus
Match: tmem135 (transmembrane protein 135 [Source:Xenbase;Acc:XB-GENE-954105])

HSP 1 Score: 160.614 bits (405), Expect = 7.439e-42
Identity = 102/351 (29.06%), Postives = 177/351 (50.43%), Query Frame = 1

Query:  538 TPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQ-LAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVI-----ELNLNSTDXXXXXXXXXXXXXXX----------XWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGST-WVFAVAGGMFLYI 1539
            TP+        L+  I  +V I H + +  NS   SK  L  L++  +G ++VT+I+A + L + F+PL+ +  ++ L+ F+++LAVG+L G ALL L+P A +     QHG   + +    K   V GG+Y+ FL+E  +  +  ++                + R  KP++       +++     ++ + + +         E++     E+ +   D                          WM++ GD +HNF DGL+IGAAFS     G+S ++AV C ELPHELGDFA+LL +G+ +++ L ++++SA   + G IIG +  + ++  T W+FA   G+FLY+
Sbjct:  237 TPQQFSLLCPALLYQIDSRVCIHHSDELT-NSKPDSKQAL--LQVLGWGALAVTVISAPSLLAVAFVPLLRRPLFRYLLRFLVALAVGTLCGDALLHLMPHAQEDHTGNQHGGKTHAIEPVLKGLSVLGGLYLLFLIENLMGLLKQRQ---------------QLKRLSKPEVPA---GDESYTTALWDLGSPVESEFCEVSRAAEILQRGNEEVEIRRRDEKDAPAPHSHSGHSHNMASKGITEIVWMVLLGDGIHNFTDGLAIGAAFSSGFSGGLSTTVAVFCHELPHELGDFAVLLQSGVPVRKVLFFSLVSAFLSFFGMIIGAVASQNSAQITPWIFAATAGIFLYV 566

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BLAST of slc39a-12 vs. Ensembl Mouse
Match: Slc39a14 (solute carrier family 39 (zinc transporter), member 14 [Source:MGI Symbol;Acc:MGI:2384851])

HSP 1 Score: 204.142 bits (518), Expect = 1.169e-58
Identity = 124/360 (34.44%), Postives = 195/360 (54.17%), Query Frame = 1

Query:  484 LSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCN---LSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLX-----XXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            LS    S +  A   ++   ++  S F+     I+ ++    C      S  + +      S++++W YGF+ VT+I+ C+ +G   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A             Q +Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  N  +  +L   +  +  +     N D   ++     + L+            N+  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI
Sbjct:   86 LSTCFSSGDLFAAHNLSERSQIGASEFQEFCPTILQQLDSQACTSENQKSEENEQTEEGKPSAIEVWGYGFLCVTVISLCSLMGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNP--------QDNYVSKSAVVFGGFYLFFFTEKILKMLLKQKNEHHHGHNHFTSETLPSKKDQEEGVTEKLQNGDLDHMIPQHCNSELDGKAPGTDEKVIVNSMSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYI 436

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BLAST of slc39a-12 vs. Ensembl Mouse
Match: Slc39a14 (solute carrier family 39 (zinc transporter), member 14 [Source:MGI Symbol;Acc:MGI:2384851])

HSP 1 Score: 197.978 bits (502), Expect = 1.992e-56
Identity = 121/360 (33.61%), Postives = 196/360 (54.44%), Query Frame = 1

Query:  484 LSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCN---LSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLX-----XXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            LS    S +  A   ++   ++  S F+     I+ ++    C      S  + +      S++++W +GF+SV++IN  + LG+L +P   K F+  ++T+ I+L++G+L  +AL  LIP+A             Q +Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  N  +  +L   +  +  +     N D   ++     + L+            N+  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI
Sbjct:   86 LSTCFSSGDLFAAHNLSERSQIGASEFQEFCPTILQQLDSQACTSENQKSEENEQTEEGKPSAIEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEAFGFNP--------QDNYVSKSAVVFGGFYLFFFTEKILKMLLKQKNEHHHGHNHFTSETLPSKKDQEEGVTEKLQNGDLDHMIPQHCNSELDGKAPGTDEKVIVNSMSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYI 436

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Query:  484 LSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCN---LSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLX-----XXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            LS    S +  A   ++   ++  S F+     I+ ++    C      S  + +      S++++W +GF+SV++IN  + LG+L +P   K F+  ++T+ I+L++G+L  +AL  LIP+A             Q +Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  N  +  +L   +  +  +     N D   ++     + L+            N+  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI
Sbjct:   86 LSTCFSSGDLFAAHNLSERSQIGASEFQEFCPTILQQLDSQACTSENQKSEENEQTEEGKPSAIEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEAFGFNP--------QDNYVSKSAVVFGGFYLFFFTEKILKMLLKQKNEHHHGHNHFTSETLPSKKDQEEGVTEKLQNGDLDHMIPQHCNSELDGKAPGTDEKVIVNSMSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYI 436

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BLAST of slc39a-12 vs. Ensembl Mouse
Match: Slc39a8 (solute carrier family 39 (metal ion transporter), member 8 [Source:MGI Symbol;Acc:MGI:1914797])

HSP 1 Score: 190.274 bits (482), Expect = 1.039e-53
Identity = 128/379 (33.77%), Postives = 208/379 (54.88%), Query Frame = 1

Query:  448 SLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSH------GSLNISRTPKPKLEIDQINS----DNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXX---XXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            S Q A DL +   ++   + +  +    ++  ++  S F  +   I+ ++    C  ++ +   ++K +LS  ++W YGF+SVTIIN  + LG++  PL+ K ++  ++T+ + LA+G+L  +A+  LIP+A        G+     +Y  KA  VFGG YM F +ER LK ++    +T+ + N  +H      GS   +  PK  L +  +N      N  +  P      +           V+ L    T+      +K   ++    +AWMI   DALHNFIDGL+IGA+ + + + G+S SIA++CEE PHELGDF ILLNAGM+ +QAL++N LSA +CY+G   G+++G   +    +FA+AGGMFLYI++
Sbjct:   59 SQQGALDLGQLHFNQCLSAEDIFSLHGFSNVTQITSSNFSAICPAILQQLNFHPCEDLRKH---NAKPSLS--EVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPEAF-------GFNPKIDNYVEKAVAVFGGFYMLFFVERTLKMLL----KTYGQ-NDHTHFRNDDFGSKEKTHQPK-TLPLPAVNGVTCYANPAVTEPNGHIHFDTV--------SVVSLQDGKTEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFA-PNIIFALAGGMFLYISL 410

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Query:  448 SLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSH------GSLNISRTPKPKLEIDQINS----DNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXX---XXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            S Q A DL +   ++   + +  +    ++  ++  S F  +   I+ ++    C  ++ +   ++K +LS  ++W YGF+SVTIIN  + LG++  PL+ K ++  ++T+ + LA+G+L  +A+  LIP+A        G+     +Y  KA  VFGG YM F +ER LK ++    +T+ + N  +H      GS   +  PK  L +  +N      N  +  P      +           V+ L    T+      +K   ++    +AWMI   DALHNFIDGL+IGA+ + + + G+S SIA++CEE PHELGDF ILLNAGM+ +QAL++N LSA +CY+G   G+++G   +    +FA+AGGMFLYI++
Sbjct:   59 SQQGALDLGQLHFNQCLSAEDIFSLHGFSNVTQITSSNFSAICPAILQQLNFHPCEDLRKH---NAKPSLS--EVWGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPEAF-------GFNPKIDNYVEKAVAVFGGFYMLFFVERTLKMLL----KTYGQ-NDHTHFRNDDFGSKEKTHQPK-TLPLPAVNGVTCYANPAVTEPNGHIHFDTV--------SVVSLQDGKTEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFA-PNIIFALAGGMFLYISL 410

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BLAST of slc39a-12 vs. UniProt/SwissProt
Match: sp|Q75N73|S39AE_MOUSE (Metal cation symporter ZIP14 OS=Mus musculus OX=10090 GN=Slc39a14 PE=1 SV=1)

HSP 1 Score: 204.142 bits (518), Expect = 8.180e-58
Identity = 124/360 (34.44%), Postives = 195/360 (54.17%), Query Frame = 1

Query:  484 LSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCN---LSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLX-----XXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            LS    S +  A   ++   ++  S F+     I+ ++    C      S  + +      S++++W YGF+ VT+I+ C+ +G   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A             Q +Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  N  +  +L   +  +  +     N D   ++     + L+            N+  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI
Sbjct:   86 LSTCFSSGDLFAAHNLSERSQIGASEFQEFCPTILQQLDSQACTSENQKSEENEQTEEGKPSAIEVWGYGFLCVTVISLCSLMGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNP--------QDNYVSKSAVVFGGFYLFFFTEKILKMLLKQKNEHHHGHNHFTSETLPSKKDQEEGVTEKLQNGDLDHMIPQHCNSELDGKAPGTDEKVIVNSMSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYI 436

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BLAST of slc39a-12 vs. UniProt/SwissProt
Match: sp|A4IGY6|S39AE_XENTR (Metal cation symporter ZIP14 OS=Xenopus tropicalis OX=8364 GN=slc39a14 PE=2 SV=1)

HSP 1 Score: 202.216 bits (513), Expect = 2.696e-57
Identity = 129/375 (34.40%), Postives = 201/375 (53.60%), Query Frame = 1

Query:  430 NLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCN---IIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQI-NSD-NHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            +L  N  +   G   +N +S+   S+   A   + S   +    F+     I+ ++    C      +  +   ++   S  ++W YGF+ VT+I+ C+  G   +P M K  YK L+ F I+LA+G+L  +AL  LIP+A        G+   + SY + ++V+FGG Y+FF  E+ LK ++ ++       +  SH S + S+    +   +++ N D +H+I  P    +            +  +L    +    +K I+   +  +AWMI   D LHNFIDGL+IGA+F+ +   G+S SIA++CEE PHELGDF ILLNAGM+I QAL +N LSA  CY+G   G++ G   S S W+FA+AGGMFLYI
Sbjct:   52 SLLENLEVGKGGGNQRN-MSQCLSSSTLFAAHNLTSGSVVDAEGFQSFCPTILQQLETRACQESPAFQNETTPGAEGRPSPGEVWGYGFLCVTVISLCSLFGAGVVPFMKKACYKRLLLFCIALAIGTLFSNALFQLIPEAF-------GFNPLEDSYVFTSSVIFGGFYLFFFTEKVLKMMLKQK-----HEHGHSHYSADTSKRDAEEGVTEKLQNGDLDHMIPPPHGSES---DLRGDEKAVQQQDLPGQQSSCYWLKGIRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGVSTSIAILCEEFPHELGDFVILLNAGMSIPQALFFNFLSACCCYLGLAFGILAGSHFS-SNWIFALAGGMFLYI 409

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BLAST of slc39a-12 vs. UniProt/SwissProt
Match: sp|A5D7L5|S39AE_BOVIN (Metal cation symporter ZIP14 OS=Bos taurus OX=9913 GN=SLC39A14 PE=2 SV=1)

HSP 1 Score: 201.445 bits (511), Expect = 8.898e-57
Identity = 116/301 (38.54%), Postives = 179/301 (59.47%), Query Frame = 1

Query:  658 SSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSD-NHLI---VAPEMK-TTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            SS+++W YG + VT+I+ C+ LG   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  +  +  +L   +  +  +     N D +H+I    + E+   T          +  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+++QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI++
Sbjct:  147 SSVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFNPMEDYYVSKSAVVFGGFYLFFFTEKILKMLLKQKNEHHHGHSHYTSETLPSQKDQEEGVTEKLQNGDLDHMIPQHCSGELDGKTPVVDEKVIVGSLSVQDLQASQSACHWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSLQQALFFNFLSACCCYVGLGFGILAGSHFS-ANWIFALAGGMFLYISL 439

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BLAST of slc39a-12 vs. UniProt/SwissProt
Match: sp|Q15043|S39AE_HUMAN (Metal cation symporter ZIP14 OS=Homo sapiens OX=9606 GN=SLC39A14 PE=1 SV=3)

HSP 1 Score: 200.675 bits (509), Expect = 1.493e-56
Identity = 114/301 (37.87%), Postives = 175/301 (58.14%), Query Frame = 1

Query:  658 SSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTL-----XXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            S++++W YG + VT+I+ C+ LG   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  +  +  SL   +  +  +     N D   ++     + L              +  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI++
Sbjct:  149 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYISL 441

[Close]

BLAST of slc39a-12 vs. UniProt/SwissProt
Match: sp|Q5RAB7|S39AE_PONAB (Metal cation symporter ZIP14 OS=Pongo abelii OX=9601 GN=SLC39A14 PE=2 SV=2)

HSP 1 Score: 199.519 bits (506), Expect = 5.030e-56
Identity = 113/301 (37.54%), Postives = 175/301 (58.14%), Query Frame = 1

Query:  658 SSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTL-----XXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            S++++W YG + VT+I+ C+ LG   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK ++ ++    +  +  +  +L   +  +  +     N D   ++     + L              +  V +L  + +    +K ++   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S + W+FA+AGGMFLYI++
Sbjct:  147 SAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASETLPSKKDQEEGVMEKLQNGDLDHMIPQHCNSELDGKAPVVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFS-ANWIFALAGGMFLYISL 439

[Close]

BLAST of slc39a-12 vs. TrEMBL
Match: A0A0H3YFM2 (Slc39a-12 OS=Schmidtea mediterranea OX=79327 GN=slc39a-12 PE=2 SV=1)

HSP 1 Score: 784.637 bits (2025), Expect = 0.000e+0
Identity = 416/416 (100.00%), Postives = 416/416 (100.00%), Query Frame = 1

Query:  298 MRHFSFVDLLAFFISLLMATESTRIDNEICFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            MRHFSFVDLLAFFISLLMATESTRIDNEICFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLNNHCNNKPNNNEVIELNLNSTDIPKIKYIKKKPVAPVAWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV
Sbjct:    1 MRHFSFVDLLAFFISLLMATESTRIDNEICFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLNNHCNNKPNNNEVIELNLNSTDIPKIKYIKKKPVAPVAWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 416

[Close]

BLAST of slc39a-12 vs. TrEMBL
Match: A0A0H3YJE9 (Slc39a-1 OS=Schmidtea mediterranea OX=79327 GN=slc39a-1 PE=2 SV=1)

HSP 1 Score: 272.707 bits (696), Expect = 1.111e-81
Identity = 157/382 (41.10%), Postives = 233/382 (60.99%), Query Frame = 1

Query:  433 LFLNFSLQNAGDLMKNKLSKANFSTEC-----LARRFVNSTPELQKSTFEGLIAM---IVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEV---IELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            LF NF ++   D  K    K N + +C        +F NS  E+     +GL      I+ +++   C  +  +  S      S L++W+YG ++VT+ N  A LGI FIPLM KK Y  +MTFM+SLA+G+L G+++LILIPD+MQ++E+       +  YK+KAT V  G+Y+FFL ER LK + N++        + SH + +    P  K EI ++ + + +    + + +L         + E     ++  +           KK +APVAWM++FGD+LHN +DG+SIGA FS + + G+S+S+AV+CEELPHELGDFA+LL AGM++KQA+ WN++SA TCY+GFIIGVI+G+ TS S W+FA AGGMFLYI++
Sbjct:   45 LFDNFKIKT--DYWKASFGKRNITEKCGPVISYLNKFSNSVVEINNE--KGLKTFNNYILSRLLNNPCGALTTSKESQK---FSVLQIWIYGLLTVTVNNVLAILGIFFIPLMKKKIYNSVMTFMVSLAIGALAGTSILILIPDSMQISEIALKAKHDKNDYKWKATGVVAGLYLFFLTERLLKSLTNQK--------TCSHATAH----PVMKFEIMKLENSDRIQSRTQTENSLLQQMKLNDKDQEKGNDCDVKNSKAKEIIHLDKTKKGIAPVAWMVVFGDSLHNLVDGMSIGAGFSQSVILGVSISLAVLCEELPHELGDFAVLLTAGMSVKQAVFWNLMSAMTCYLGFIIGVIVGDITSASVWIFAFAGGMFLYISL 407

[Close]

BLAST of slc39a-12 vs. TrEMBL
Match: A0A0L8G579 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22000186mg PE=4 SV=1)

HSP 1 Score: 251.136 bits (640), Expect = 2.935e-72
Identity = 153/341 (44.87%), Postives = 211/341 (61.88%), Query Frame = 1

Query:  610 CNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLK----WIINKEV-----------RTFNRANSLSHGSLNISR---TPKPKLEIDQ-----INSDNHLIVAPEMKTTLXXXXXXXXXXXEV-IELNLNST-----DXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            C  + + +  ++K    S + W +GF+ VT+IN CA  G++ +P+MN + YK ++ F+++LAVGSL GS LL+LIP+A +L   Q    GY     + +T + GGVY+FFL+ERFLK    W  N              +  NR  S    + NIS    + K K  +D       +  N+   A +  ++L    +++  + +V  E N N       +   IK  KKKP+  VAWMIIFGDALHNFIDGLSIGAAFS + MTGIS+S+AVICEELPHELGDFAILLN+GM +K+AL++N LSA  CY+G I G++L E T+  TW+F VAGGMFLYI++
Sbjct:  175 CKTVPVGNQKYNK----SAEAWGFGFLFVTLINLCALCGVVVLPVMNTRVYKKVLLFLVALAVGSLAGSGLLVLIPEAFELVGTQEDRHGYL----WMSTTIMGGVYLFFLIERFLKSAFEWKKNNNDDDEAEYSMIMDKNKNRQISCVEENPNISDIVCSVKSKTPVDNDTAKLKDPSNYHASASQCTSSLGRTNSSEFLDIQVKTETNCNDNSRGDYNDCIIKTNKKKPIKTVAWMIIFGDALHNFIDGLSIGAAFSSSVMTGISVSLAVICEELPHELGDFAILLNSGMTLKRALLFNFLSACMCYVGLIFGIVLAEVTAAHTWIFGVAGGMFLYISL 507

[Close]

BLAST of slc39a-12 vs. TrEMBL
Match: A0A1I8I022 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 241.121 bits (614), Expect = 1.152e-69
Identity = 153/392 (39.03%), Postives = 212/392 (54.08%), Query Frame = 1

Query:  571 LIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLA--------------------ELQHGYPGYQVSYK----------YKATVVFGGVYMFFLLERFLKWIINKE----------------VRTFNRANSLSHGSLNISRTPKPKLE--------------IDQINSDNHLIVAPEMKT-TLXXXXXXXXXXXEVIE------LNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            L++ ++  V  P C I +L         +++  MW YG + VT+IN CA LGI+F+P M ++F+K+LMTFM+SLAVGSL G+ALLIL+PD +QLA                     L H       ++K          ++   VFGG+YMFF++ER LK +I K+                V+   ++  + HG  +      P  +                Q ++D     AP   T  L  +        E IE         +  +  +        V PVAWMI+ GDALHNFIDGLSIGAAF+ +T++G+S+ +AV+CEELPHELGDFAILL+AGM++  AL+ N LSA TCY+GF +GV LGE T  S W+FAVA GMFLYI++
Sbjct:   74 LVSTLLGGVQTPDCYIQQL---------VAADDMWGYGLLFVTLINLCAVLGIIFLPFMGRRFFKLLMTFMVSLAVGSLMGTALLILLPDCLQLAFMHEEVNKANSSLIDDDRQLHLFHAENSGHTAWKDFLSQHPWYLWRCCAVFGGIYMFFIIERMLKELIRKKHSSCTTEIIDTMEFLNVQKPEQSGGIGHGRSHSLPAAAPTGDSSSLANFKTAEICFTPQESADQDRSKAPSSPTGELAANGAAIVLPIEAIENGDACYSQTDMVNSNRDVSTWLAKVQPVAWMILLGDALHNFIDGLSIGAAFTRSTLSGVSICLAVLCEELPHELGDFAILLSAGMSMPMALLCNFLSACTCYLGFALGVWLGE-TGASVWIFAVASGMFLYISL 455

[Close]

BLAST of slc39a-12 vs. TrEMBL
Match: A0A1I8GYN7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 241.506 bits (615), Expect = 1.387e-69
Identity = 158/429 (36.83%), Postives = 223/429 (51.98%), Query Frame = 1

Query:  475 KNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSK-----CNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLA--------------------ELQHGYPGYQVSYK----------YKATVVFGGVYMFFLLERFLKWIINKE----------------VRTFNRANSLSHGSLNISRTPKPKLE--------------IDQINSDNHLIVAPEMKT-TLXXXXXXXXXXXEVIE------LNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
             N LS+     EC ++     +    +     L++ ++  V  P C I +L +   S+        + L +W YG + VT+IN CA LGI+F+P M ++F+K+LMTFM+SLAVGSL  +ALLIL+PD +QLA                     L H       ++K          ++   VFGG+YMFF++ER LK +I K+                V+   ++  + HG  +      P  +                Q ++D     AP   T  L  +        E IE         +  +  +        V PVAWMI+ GDALHNFIDGLSIGAAF+ +T++G+S+ +AV+CEELPHELGDFAILL+AGM++  AL+ N LSA TCY+GF +GV LGE T  S W+FAVA GMFLYI++
Sbjct:   42 SNLLSRVTSVMECPSQSQSIESLTWTRDNATHLVSTLLGGVQTPDCYIQQLVAADDSEHGGGHTAQNPLHVWGYGLLFVTLINLCAVLGIIFLPFMGRRFFKLLMTFMVSLAVGSLVATALLILLPDCLQLAFMHEEVNKANSSLIDDDRQLHLFHAENSGHTAWKDFLSQHPWYLWRCCAVFGGIYMFFIIERMLKELIRKKHSSCTTEIIDTMEFLNVQKPEQSGGIGHGRSHSLPAAAPTGDSSSLANFKTAEICFTPQESADQDRSKAPSSPTGELAANGAAIVLPIEAIENGDACYSQTDMVNSNRDVSTWLAKVQPVAWMILLGDALHNFIDGLSIGAAFTRSTLSGVSICLAVLCEELPHELGDFAILLSAGMSMPMALLCNFLSACTCYLGFALGVWLGE-TGASVWIFAVASGMFLYISL 469

[Close]

BLAST of slc39a-12 vs. Ensembl Cavefish
Match: slc39a14 (solute carrier family 39 member 14 [Source:NCBI gene;Acc:799782])

HSP 1 Score: 196.052 bits (497), Expect = 1.800e-56
Identity = 117/320 (36.56%), Postives = 171/320 (53.44%), Query Frame = 1

Query:  610 CNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWII---NKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINS-------DNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            C   +   P  S    +  ++W YGF+ VT+I+ C+ +G   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+   +  Y  K+ VVFGG Y+FF  E+ LK I+   NK     +   +  + + ++      KL+  +          D  +    E    L+       ++         +     +K      +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G   S   W+FA+AGGMFLYI
Sbjct:   45 CRAQQDQEPDSSP-RPTYAEVWGYGFLCVTVISLCSLVGASVVPFMRKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFDPLEAYYVSKSAVVFGGFYLFFFTEKVLKMILKPKNKGGHGHSHFPAEQYSNGDVEDGVMEKLQNGEAGGGVSLPRVDGEIRGVAEEDKMLSTPQQTVQDSQSAGGGGGGTGGCYWLKGRSYSDIGTLAWMITLSDGLHNFIDGLAIGASFTASVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGMAFGILAGNQFS-PNWIFALAGGMFLYI 355

[Close]

BLAST of slc39a-12 vs. Ensembl Cavefish
Match: ENSAMXT00000003334.2 (zinc transporter ZIP8-like [Source:NCBI gene;Acc:103022239])

HSP 1 Score: 183.726 bits (465), Expect = 1.162e-51
Identity = 119/332 (35.84%), Postives = 178/332 (53.61%), Query Frame = 1

Query:  544 ELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
             L +     +   ++++ ++P C  +     +     L    +W YGF++VTIIN  + LG+L IPL  K ++  ++T+ I LA+G+L  +A L LIP+A+       G+     +Y  KA  +FGG Y+ F  E+ LK ++  E           HG  + S    P+     I +          KT++ +         +            +        V  VAWMI   DALHNFIDGL+IGA+F+ + +TG S SIA++CEE PHELGDF ILLNAGM + QA+ +N+LSA +CYIG ++G++LG T +    +FA+AGGMFLYI
Sbjct:   82 HLNQDNLRTICPALLNQALLPTCTPLAAQPQA-----LVQDHVWGYGFLAVTIINLFSLLGLLLIPLTKKPYFPKVLTYFIGLAIGTLFSNAALQLIPEAL-------GFDPKADNYILKAVGIFGGFYLLFFTEKVLKMVLKTEHE---------HGHSHFSPPEVPRQNGGTIIAVTSFSNPSSEKTSIASDPPEDQLTAD------PQVSCMRRVGQHLASVRTVAWMITLSDALHNFIDGLAIGASFTVSILTGFSTSIAIVCEEFPHELGDFVILLNAGMTVPQAIFFNLLSAMSCYIGLVLGILLGSTFA-PNIIFAIAGGMFLYI 385

[Close]

BLAST of slc39a-12 vs. Ensembl Cavefish
Match: ENSAMXT00000004885.2 (zinc transporter ZIP4 [Source:NCBI gene;Acc:103045007])

HSP 1 Score: 149.828 bits (377), Expect = 1.581e-39
Identity = 113/371 (30.46%), Postives = 182/371 (49.06%), Query Frame = 1

Query:  499 FSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHC-NIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMN-KKFYKVLMTFMISLAVGSLTGSALLILIPDAMQL---AELQ---HGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTF---------NRANSLSHGSL--NISRTPKPKLEIDQ---INSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            FS + L   +  ++  L +  F  L   ++ +++   C     + +P+  K  LS+ + ++Y  ++ T+I   A  GI+ +   +   F+++ + F ISLAVGSLTG ALL L+P  + L    E Q   HG+     +Y +K  VV GG+Y F+L+E     I  K                 +   HG +     R  K KL   Q   ++ +N++   PE                   E  L                  + +MI   D +HNF DGL+IGAAFS +  +G++ S+AV+C ELPHELGDFA+LL+ G+++K+AL+ N+ SA T +IG  I + +   ++   W+ AV  G+FLY+ +
Sbjct:  291 FSAQELLMIYRLNSSGLNRDQFTQLSPALIQQLLSKACTETSPITNPTGDK--LSTTERYLYATLANTVICLMAMFGIVMLLCTSCSGFFQLSIQFCISLAVGSLTGDALLHLLPTFLGLHVHGEGQSDGHGHSEENSTYIFKLLVVVGGIYYFYLMETIFSIITRKNSDHHHHHHHHGEEGDPHHCDHGKVLQMYQREKKNKLSTSQAELVDGENNIKSIPEPAP-------------RTREQKL------------------LPYMITISDGIHNFADGLAIGAAFSLSWRSGLATSLAVLCHELPHELGDFAVLLHCGVSVKKALLLNVGSALTSFIGLYIALSVSTDSTAKEWIAAVTTGLFLYVGL 628

HSP 2 Score: 33.4982 bits (75), Expect = 1.581e-39
Identity = 13/27 (48.15%), Postives = 20/27 (74.07%), Query Frame = 2

Query: 1613 FIIQNIGLLMGYSILLLMALYGDKISI 1693
            F +QN+GL  G+ ILLL++ + DKI +
Sbjct:  647 FALQNLGLWTGWGILLLLSFFEDKIGV 673

[Close]

BLAST of slc39a-12 vs. Ensembl Cavefish
Match: slc39a8 (zinc transporter ZIP8 [Source:NCBI gene;Acc:103035991])

HSP 1 Score: 150.599 bits (379), Expect = 1.635e-39
Identity = 120/396 (30.30%), Postives = 207/396 (52.27%), Query Frame = 1

Query:  391 SKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRT----FNRANSLSHGSLNISRTPKPKLEIDQINSD-----NHLIV--APEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            S ++  NF+ L  +     S+ N  + ++N+   +    E LA   +++  E+       +   ++ +V++P C      +P  ++   S  ++W Y F++VTIIN  + LG+L +P   K ++  ++T+ I +A+G+L  +A+L LIP+A+       G+      Y   A  +FGG Y+ F  E+ LK  +  +       F  + +    + + S      L I  I+++     NH I+   P  K +  +   N   +    +          ++      +  VAWMI   DALHNFIDGL+IGA+F+ + + G   SIA+ CEE PHE+GDF ILL++GM++ QA  +N++SA  CY+G  +G++LG   + +  +FA+AGGMFLYI++
Sbjct:   20 STTNLGNFLQLISSRRPPASIDNDANPLRNEECLS--LPELLAVFGLSNVSEVTADQLHLMCPAVLTQVLLPSCPF----TPPLTQTIDS--QVWGYSFLAVTIINLASLLGLLLVPFTKKPYFPKVLTYFIGVAIGTLFSNAVLQLIPEAL-------GFDPKADDYVLNAVGIFGGFYLLFFTEKVLKMALKADSADCHSHFPSSQTTDENATHFSN----DLVISNISNNVNPNINHEIIPNGPREKPSNLSPVVNPVVSPVNEQDACVVLSCRWLRGEHVSNIKTVAWMITLSDALHNFIDGLAIGASFTLSLIAGFGTSIAIFCEEFPHEIGDFVILLSSGMSVPQAAFFNLMSAMCCYLGLALGILLGSNFAPNA-IFAIAGGMFLYISL 395

[Close]

BLAST of slc39a-12 vs. Ensembl Cavefish
Match: ENSAMXT00000045640.1 (zinc transporter ZIP4 [Source:NCBI gene;Acc:103045007])

HSP 1 Score: 149.443 bits (376), Expect = 2.223e-39
Identity = 113/371 (30.46%), Postives = 182/371 (49.06%), Query Frame = 1

Query:  499 FSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHC-NIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMN-KKFYKVLMTFMISLAVGSLTGSALLILIPDAMQL---AELQ---HGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTF---------NRANSLSHGSL--NISRTPKPKLEIDQ---INSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            FS + L   +  ++  L +  F  L   ++ +++   C     + +P+  K  LS+ + ++Y  ++ T+I   A  GI+ +   +   F+++ + F ISLAVGSLTG ALL L+P  + L    E Q   HG+     +Y +K  VV GG+Y F+L+E     I  K                 +   HG +     R  K KL   Q   ++ +N++   PE                   E  L                  + +MI   D +HNF DGL+IGAAFS +  +G++ S+AV+C ELPHELGDFA+LL+ G+++K+AL+ N+ SA T +IG  I + +   ++   W+ AV  G+FLY+ +
Sbjct:  196 FSAQELLMIYRLNSSGLNRDQFTQLSPALIQQLLSKACTETSPITNPTGDK--LSTTERYLYATLANTVICLMAMFGIVMLLCTSCSGFFQLSIQFCISLAVGSLTGDALLHLLPTFLGLHVHGEGQSDGHGHSEENSTYIFKLLVVVGGIYYFYLMETIFSIITRKNSDHHHHHHHHGEEGDPHHCDHGKVLQMYQREKKNKLSTSQAELVDGENNIKSIPEPAP-------------RTREQKL------------------LPYMITISDGIHNFADGLAIGAAFSLSWRSGLATSLAVLCHELPHELGDFAVLLHCGVSVKKALLLNVGSALTSFIGLYIALSVSTDSTAKEWIAAVTTGLFLYVGL 533

HSP 2 Score: 33.4982 bits (75), Expect = 2.223e-39
Identity = 13/27 (48.15%), Postives = 20/27 (74.07%), Query Frame = 2

Query: 1613 FIIQNIGLLMGYSILLLMALYGDKISI 1693
            F +QN+GL  G+ ILLL++ + DKI +
Sbjct:  552 FALQNLGLWTGWGILLLLSFFEDKIGV 578

[Close]

BLAST of slc39a-12 vs. Ensembl Sea Lamprey
Match: slc39a14 (solute carrier family 39 member 14 [Source:NCBI gene;Acc:799782])

HSP 1 Score: 205.682 bits (522), Expect = 1.454e-61
Identity = 121/294 (41.16%), Postives = 175/294 (59.52%), Query Frame = 1

Query:  670 MWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWII-NKEVRTFNRANSLS-HGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            +W YGF+ VTII+ C+ +G   +P M KKFY+ L+ + I+LA+G+L  +AL  LIP+A  L  ++ GY        YK+ VVF G Y+FF  E+ LK ++  K+ R  NRA   S    L    T   K   D     ++    P +    + H  +  + +   E  ++      +K  +   +  +AWMI   D LHNFIDGL+IGA+F+ +   GIS SIA++CEE PHELGDF ILLNAGM+I+QAL +N LSA +CY+G + G++ G   +   W+FA+AGGMFLYI++
Sbjct:   16 VWGYGFLCVTIISLCSLVGASVVPFMRKKFYRRLLMYFIALAIGTLYSNALFQLIPEAFGLDPVKDGY-------VYKSAVVFAGFYLFFFAEKILKMVLKQKDERPPNRAECYSSQPDLEDGATETLKAIEDGTEHQSN-GNPPHLAGGGHGHHTHVTHEHANEEAQVSEGMCYWLKGTRYSRIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSIAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACSCYLGLVCGIVAGSHFA-HNWIFALAGGMFLYISL 300

[Close]

BLAST of slc39a-12 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000371.1 (pep scaffold:Pmarinus_7.0:GL476519:142118:151022:-1 gene:ENSPMAG00000000332.1 transcript:ENSPMAT00000000371.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 138.272 bits (347), Expect = 4.133e-38
Identity = 62/104 (59.62%), Postives = 82/104 (78.85%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGE-TTSGSTWVFAVAGGMFLYI 1539
            WM+I GD +HNF DGL+IGAAFS +T  G+S SIAV C ELPHELGDFA+LL AGM++KQA+++N+LSA   Y+G +IG  +G+ T S +TW+FA   G+FLY+
Sbjct:  741 WMVILGDGVHNFSDGLAIGAAFSDSTSVGLSTSIAVFCHELPHELGDFAVLLKAGMSVKQAIVYNLLSALLGYLGLVIGTAVGQYTHSVTTWIFAATAGIFLYV 844

HSP 2 Score: 37.7354 bits (86), Expect = 4.133e-38
Identity = 16/38 (42.11%), Postives = 26/38 (68.42%), Query Frame = 2

Query: 1580 VEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGDKISI 1693
            V+   +G    F++QN+GLLMG+ I+L++A Y + I I
Sbjct:  858 VDSHSYGRLGCFLLQNLGLLMGFGIMLVIARYEEHIKI 895

HSP 3 Score: 76.2554 bits (186), Expect = 8.718e-15
Identity = 38/108 (35.19%), Postives = 68/108 (62.96%), Query Frame = 1

Query:  658 SSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGY--------QVSYKYKATVVFGGVYMFFLLERFL 957
            S++  W +GF+S+TII+  + LG+  +P+MN+ F+K L+TF+++LAVG+L+G ALL L+P + Q +   +G+  +         +   +K     GG+Y+ F++E  L
Sbjct:  481 SNMPAWGWGFLSITIISMLSLLGVAIVPMMNQVFFKYLLTFLVALAVGTLSGDALLHLLPHS-QNSHSHNGHDDHDHILDSDEHLDGIWKGLTGLGGIYLMFIVEHLL 587

[Close]

BLAST of slc39a-12 vs. Ensembl Sea Lamprey
Match: SLC39A12 (solute carrier family 39 member 12 [Source:HGNC Symbol;Acc:HGNC:20860])

HSP 1 Score: 132.88 bits (333), Expect = 2.043e-36
Identity = 94/353 (26.63%), Postives = 171/353 (48.44%), Query Frame = 1

Query:  547 LQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMN-KKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQV------SYKYKATVVFGGVYMFFLLERFLKWII---NKEVRTFNRANSLSHG-------SLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHEL---GDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            + +  F  L   IV +++   C +      +      ++++ + YG ++V +++  + +G+  I + + ++ Y+V++   I+LAVG+L+G A L LIP  + L +   G+   +       S+ +K   + GG+YMFFL+E+    +I     E     + N   H        S    +  +      +++++    V P    TL     ++     +  L +                     MI+ GD++HNF DGL++GAAFS +   G++ S+A+   E+PHE+   GDFA LLN+GM +  AL+ N +S+ T + G  +G+ L   T    W+F+V  GMF YI++
Sbjct:   18 VARRNFSALAVAIVQQLLSGACWVHGDEEATAPGAAPTTVEKYGYGTLAVLVVSLSSLMGVAVILVTSCQETYRVILQTFIALAVGTLSGDATLHLIPTMLVLHDHSDGHNHAEEDFVEKNSHVWKLMALLGGIYMFFLVEKIFHLLIASSQGEREQQQQQNHCGHSHDLALRDSFRAGKAGRGTASTTRLDTEEEAEVTP----TLVALPKHRGTFKGMSSLAI---------------------MILVGDSIHNFADGLAMGAAFSASNRAGLTTSLAIFFHEVPHEIERSGDFAALLNSGMRVCPALVLNFISSLTAFTGLYVGLSLSNDTIVQQWIFSVTAGMFYYISL 345

HSP 2 Score: 37.7354 bits (86), Expect = 2.043e-36
Identity = 15/27 (55.56%), Postives = 24/27 (88.89%), Query Frame = 2

Query: 1613 FIIQNIGLLMGYSILLLMALYGDKISI 1693
            F +QN+GLL G+SI++L+A++ D+ISI
Sbjct:  364 FALQNVGLLAGWSIMVLLAVFEDQISI 390

[Close]

BLAST of slc39a-12 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009266.1 (pep scaffold:Pmarinus_7.0:GL483721:1641:4019:1 gene:ENSPMAG00000008381.1 transcript:ENSPMAT00000009266.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.219 bits (256), Expect = 2.881e-26
Identity = 52/106 (49.06%), Postives = 72/106 (67.92%), Query Frame = 1

Query: 1234 MIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV*N 1551
            M++ GD LHNF DGL++GAAFS +   G++  +AV   ELPHE+  F+ILLN G++I+ AL  N+LSA T  IGF IG  + E  +   W+ A A GMFLY+++ N
Sbjct:    1 MVLIGDGLHNFADGLALGAAFSLSLSDGLATMLAVALHELPHEIDIFSILLNTGLSIQAALGLNLLSALTALIGFYIGASVSENETAMQWIIAFATGMFLYLSINN 106

[Close]

BLAST of slc39a-12 vs. Ensembl Yeast
Match: YKE4 (Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family [Source:SGD;Acc:S000001285])

HSP 1 Score: 62.3882 bits (150), Expect = 5.455e-11
Identity = 31/75 (41.33%), Postives = 45/75 (60.00%), Query Frame = 1

Query: 1258 HNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGE 1482
            H+  DG+++  +F  +T  GI  SIAV   E+PHELGDFAILL++G    QA+    ++A    +G  IG  + E
Sbjct:  197 HHITDGIALATSFYSSTQVGIMTSIAVTFHEIPHELGDFAILLSSGFTFPQAIRAQAVTAFGAVVGTSIGCWMNE 271

[Close]

BLAST of slc39a-12 vs. Ensembl Nematostella
Match: EDO37361 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG18])

HSP 1 Score: 136.346 bits (342), Expect = 8.561e-38
Identity = 58/102 (56.86%), Postives = 83/102 (81.37%), Query Frame = 1

Query: 1234 MIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            M++ GD++HNF+DGL+IGAAFS++ + G S S+A+ CEE+PHELGDFA+LL+ GM ++QAL +N LSA  C++G  IG++LG TT    W++A+AGGMF+YI
Sbjct:    1 MVLLGDSMHNFLDGLAIGAAFSNSIIEGFSTSLAIFCEEVPHELGDFAVLLSGGMTVRQALGFNFLSACVCFVGMAIGLLLGYTTHAVKWIYALAGGMFVYI 102

[Close]

BLAST of slc39a-12 vs. Ensembl Nematostella
Match: EDO29311 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T403])

HSP 1 Score: 128.257 bits (321), Expect = 8.677e-35
Identity = 54/105 (51.43%), Postives = 82/105 (78.10%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            W I+ GD +HNFIDG++IGAAFS + + GIS ++A+I EE+PHELGDFA+LL++GM  + A+++N+LS   CY G ++G++L   T+   W++A+A GMFLYI++
Sbjct:    7 WTIVIGDCVHNFIDGVAIGAAFSSSVVEGISTALAIIGEEVPHELGDFAVLLSSGMKYRHAVLFNLLSGVICYTGLVLGLLLAYATASVQWIYAIAAGMFLYISL 111

[Close]

BLAST of slc39a-12 vs. Ensembl Nematostella
Match: EDO47899 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLA9])

HSP 1 Score: 129.413 bits (324), Expect = 2.087e-34
Identity = 53/105 (50.48%), Postives = 82/105 (78.10%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            W I+ GD +HNFIDG++IGAAFS + + GIS ++A++ EE+PHELGDFA+LL++GM  + A+++N+LS   CY G ++G++L   T+   W++A+A GMFLYI++
Sbjct:  121 WTIVIGDCVHNFIDGVAIGAAFSSSVVEGISTALAILGEEVPHELGDFAVLLSSGMKYRHAVLFNLLSGVICYTGLVLGLLLAYATASVQWIYAIAAGMFLYISL 225

HSP 2 Score: 35.039 bits (79), Expect = 2.087e-34
Identity = 18/41 (43.90%), Postives = 27/41 (65.85%), Query Frame = 2

Query: 1565 EDKDSVEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGDKI 1687
            E K SV    +   KTF +QN G+L+G+SI+L++A+Y   I
Sbjct:  239 EGKHSV----WSNLKTFALQNSGMLVGFSIMLVLAIYAHDI 275

HSP 3 Score: 60.8474 bits (146), Expect = 2.797e-10
Identity = 35/113 (30.97%), Postives = 56/113 (49.56%), Query Frame = 1

Query:  499 FSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIP 837
            FST  L   +  +   + ++TF  +   +V +V    C  +              LK W YGF++ TI+N    +G+  +P M+   YK ++ FM+SLAVG L G ++  LIP
Sbjct:    2 FSTSSLLAVYGLNETLVNETTFARVCPAVVQQVSNQACRRVAGEKRDDHVFKEPELKAWGYGFLATTIVNIAPLIGVTVVPFMSVAVYKTVLLFMVSLAVGVLCGGSVFHLIP 114

[Close]

BLAST of slc39a-12 vs. Ensembl Nematostella
Match: EDO47900 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLB0])

HSP 1 Score: 125.176 bits (313), Expect = 1.093e-33
Identity = 60/107 (56.07%), Postives = 84/107 (78.50%), Query Frame = 1

Query: 1231 WMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV*N 1551
            WMI+ GDALHNFIDGL+IGA +S + + G S ++A+ CEELPHELGDFA+LLN GM  KQA+ +N +SA TC++G ++G++LG  T    W++A+A GMF+YI++ N
Sbjct:    6 WMIVLGDALHNFIDGLAIGAGYSSSILEGASTALAIFCEELPHELGDFAVLLNGGMTYKQAMFFNFISACTCFLGLVMGLLLGYATPAVKWIYALAAGMFIYISLVN 112

[Close]

BLAST of slc39a-12 vs. Ensembl Nematostella
Match: EDO49001 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHM0])

HSP 1 Score: 122.094 bits (305), Expect = 1.304e-32
Identity = 62/106 (58.49%), Postives = 79/106 (74.53%), Query Frame = 1

Query: 1234 MIIFGDALHNFIDGLSIGAAFSHNTMTGISLSI----AVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            MII GD +HN  DGL+IGAAFS    +GIS  I    AV C ELPHELGDFA+LL AGM++K AL+ N+LSA +CY+G IIG+++G+      W+FAVAGGMF+Y+
Sbjct:    1 MIIIGDTIHNISDGLAIGAAFSEGGSSGISGGISTSIAVFCHELPHELGDFAVLLTAGMSVKMALLANLLSACSCYLGLIIGIVIGQQMEVRLWIFAVAGGMFIYV 106

[Close]

BLAST of slc39a-12 vs. Ensembl Medaka
Match: slc39a14 (solute carrier family 39 member 14 [Source:NCBI gene;Acc:101159804])

HSP 1 Score: 192.971 bits (489), Expect = 1.275e-54
Identity = 113/293 (38.57%), Postives = 167/293 (57.00%), Query Frame = 1

Query:  661 SLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            +L +W YG + VT+I+ C+ +G   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+      Y  K+ VVFGG Y+FF  E+ LK ++ ++  +    ++  H S      P    E  Q N +   +   ++ +       + P   +V     +      +K      +  +AWMI   D LHNFIDGL+IGA+F+ +   G+S S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G + S   W+FA+AGGMFLYI
Sbjct:  154 TLLLWGYGILCVTLISLCSLIGASVVPFMRKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFDPLVDFYVSKSAVVFGGFYLFFFTEKVLKVLLKQKRGSHAHFSAPDHYS-----APDGDAEKLQQNGEAGALARDKVDSGEGELMLSPPQTLQVC----SHGGCYWLKRTAYSDIGTLAWMITLSDGLHNFIDGLAIGASFTASVFQGVSTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGMGFGILAGNSFS-PNWIFALAGGMFLYI 429

[Close]

BLAST of slc39a-12 vs. Ensembl Medaka
Match: slc39a14 (solute carrier family 39 member 14 [Source:NCBI gene;Acc:101159804])

HSP 1 Score: 191.43 bits (485), Expect = 5.599e-54
Identity = 114/309 (36.89%), Postives = 174/309 (56.31%), Query Frame = 1

Query:  637 SHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPK-------LEIDQINS-DNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            + S    +  ++W YG + VT+I+ C+ +G   +P M K FYK L+ + I+LA+G+L  +AL  LIP+A        G+      Y  K+ VVFGG Y+FF  E+ LK ++ ++  +    ++  H S       K +       L  D+++S +  L+++P             P + +    + +      +K      +  +AWMI   D LHNFIDGL+IGA+F+ +   G+S S+A++CEE PHELGDF ILLNAGM+I+QAL +N LSA  CY+G   G++ G + S   W+FA+AGGMFLYI
Sbjct:  146 TDSASRPTDAEVWGYGILCVTLISLCSLIGASVVPFMRKTFYKRLLLYFIALAIGTLYSNALFQLIPEAF-------GFDPLVDFYVSKSAVVFGGFYLFFFTEKVLKVLLKQKRGSHAHFSAPDHYSAPDGDAEKLQQNGEAGALARDKVDSGEGELMLSPPQT-------LQDPQSPDTRGRSSSHGGCYWLKRTAYSDIGTLAWMITLSDGLHNFIDGLAIGASFTASVFQGVSTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGMGFGILAGNSFS-PNWIFALAGGMFLYI 439

[Close]

BLAST of slc39a-12 vs. Ensembl Medaka
Match: slc39a8 (solute carrier family 39 member 8 [Source:NCBI gene;Acc:101159549])

HSP 1 Score: 186.808 bits (473), Expect = 5.404e-53
Identity = 115/325 (35.38%), Postives = 183/325 (56.31%), Query Frame = 1

Query:  583 IVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNR----ANSLSHGSLNISRTPKPK--LEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            ++ +V++P C        +          +W YGF++VTIIN  + LG+L IP   K ++  ++++ I LA+G+L  +A+L LIP+A+       G+     SY   +  +FGG Y+ F +E+ LK  +  +    +     A+  +   L     P+ K  + + QI +D +    P+  T                E+ ++ T    ++  +   +  VAWMI  GDALHNFIDGL+IGA+F+ + +TG S S A+ CEE PHELGDF ILLN+GM++ QA+ +N+LSA +CYIG + G++LG + + +  +FA+AGGMFLYI
Sbjct:  106 VLTQVLLPSCPYT-----APPPLPPLDYSVWGYGFLAVTIINLASLLGLLLIPFTKKSYFPKVLSYFIGLAIGTLFSNAVLQLIPEAL-------GFNPNADSYVENSVAIFGGFYLLFFVEKVLKMCLGLDGEHGHSHSSPADPPTESYLQNGGVPEKKDSVVLAQIVTDRNYPEPPQTPTQ---------------EVQVSGTMCHWLRGQRITNIKTVAWMITLGDALHNFIDGLAIGASFTVSVLTGFSTSTAIFCEEFPHELGDFVILLNSGMSVPQAVFFNLLSAMSCYIGLVFGILLGSSFAPNA-IFAIAGGMFLYI 402

[Close]

BLAST of slc39a-12 vs. Ensembl Medaka
Match: slc39a8 (solute carrier family 39 member 8 [Source:NCBI gene;Acc:101159549])

HSP 1 Score: 186.808 bits (473), Expect = 1.340e-52
Identity = 115/325 (35.38%), Postives = 183/325 (56.31%), Query Frame = 1

Query:  583 IVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNR----ANSLSHGSLNISRTPKPK--LEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI 1539
            ++ +V++P C        +          +W YGF++VTIIN  + LG+L IP   K ++  ++++ I LA+G+L  +A+L LIP+A+       G+     SY   +  +FGG Y+ F +E+ LK  +  +    +     A+  +   L     P+ K  + + QI +D +    P+  T                E+ ++ T    ++  +   +  VAWMI  GDALHNFIDGL+IGA+F+ + +TG S S A+ CEE PHELGDF ILLN+GM++ QA+ +N+LSA +CYIG + G++LG + + +  +FA+AGGMFLYI
Sbjct:  106 VLTQVLLPSCPYT-----APPPLPPLDYSVWGYGFLAVTIINLASLLGLLLIPFTKKSYFPKVLSYFIGLAIGTLFSNAVLQLIPEAL-------GFNPNADSYVENSVAIFGGFYLLFFVEKVLKMCLGLDGEHGHSHSSPADPPTESYLQNGGVPEKKDSVVLAQIVTDRNYPEPPQTPTQ---------------EVQVSGTMCHWLRGQRITNIKTVAWMITLGDALHNFIDGLAIGASFTVSVLTGFSTSTAIFCEEFPHELGDFVILLNSGMSVPQAVFFNLLSAMSCYIGLVFGILLGSSFAPNA-IFAIAGGMFLYI 402

[Close]

BLAST of slc39a-12 vs. Ensembl Medaka
Match: ENSORLT00000030843.1 (solute carrier family 39 member 4 [Source:NCBI gene;Acc:101165941])

HSP 1 Score: 144.821 bits (364), Expect = 1.460e-39
Identity = 93/314 (29.62%), Postives = 161/314 (51.27%), Query Frame = 1

Query:  652 NLSSLKMWVYGFISVTIINACAGLGILFIPLMN-KKFYKVLMTFMISLAVGSLTGSALLILIPDAMQL-----------AELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTF---NRANSLSHGS-LNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
             L+  + ++Y  ++  +I   + LGI+ +   +    +++ + F IS+AVGSLTG ALL L+P  + L              + G P     Y YK     GG+Y+F+L+E     I  +        +  +   HG  L + +  + + + +Q  S+  L+   + K+              V +LN +  +   +            +MI  GD +HNF DGL++GAAFS +  +G++ S+AV+C ELPHE+GDFAILL +GM++ +AL+ N+ SA   ++G  I + +    + + W+ AVAGG+F+Y+ +
Sbjct:  361 GLTEAERYLYATVANVVITLVSMLGIVLLLCTSCTNVFQLCIQFCISMAVGSLTGDALLHLVPMFLGLHVHSDEDSSSDHSHEEGIP----DYTYKMLAALGGIYLFYLMESIFSLITQENHHQHAEESDPHHCDHGRVLEMFQKERRQKDRNQSTSETDLVEIEKQKS--------------VSDLNEDKRETRMLP-----------YMITIGDGIHNFADGLAVGAAFSLSWKSGLATSVAVLCHELPHEVGDFAILLYSGMSVPRALLLNLASAMISFVGLYIALSVATDFATTQWITAVAGGLFMYVGL 645

HSP 2 Score: 38.891 bits (89), Expect = 1.460e-39
Identity = 16/26 (61.54%), Postives = 23/26 (88.46%), Query Frame = 2

Query: 1610 TFIIQNIGLLMGYSILLLMALYGDKI 1687
            TF +QN+GLL G+S+LLL++L+ DKI
Sbjct:  663 TFALQNLGLLTGWSVLLLLSLFEDKI 688

[Close]

BLAST of slc39a-12 vs. Planmine SMEST
Match: SMESG000016243.1 (SMESG000016243.1)

HSP 1 Score: 778.474 bits (2009), Expect = 0.000e+0
Identity = 411/416 (98.80%), Postives = 415/416 (99.76%), Query Frame = 1

Query:  298 MRHFSFVDLLAFFISLLMATESTRIDNEICFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            MRHFSF DLLAFFISLLMATESTRIDNEICFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSS+KMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKW+INKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLNNHCNNKPNNNEVIELNLNSTDIPKIKYIKKKPVAPVAWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI++
Sbjct:    1 MRHFSFGDLLAFFISLLMATESTRIDNEICFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSVKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWMINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLNNHCNNKPNNNEVIELNLNSTDIPKIKYIKKKPVAPVAWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYISL 416

HSP 2 Score: 102.449 bits (254), Expect = 6.829e-23
Identity = 51/51 (100.00%), Postives = 51/51 (100.00%), Query Frame = 2

Query: 1541 MSEMNATLEDKDSVEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGDKISI 1693
            MSEMNATLEDKDSVEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGDKISI
Sbjct:  420 MSEMNATLEDKDSVEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGDKISI 470

[Close]

BLAST of slc39a-12 vs. Planmine SMEST
Match: SMESG000016243.1 (SMESG000016243.1)

HSP 1 Score: 749.199 bits (1933), Expect = 0.000e+0
Identity = 395/399 (99.00%), Postives = 399/399 (100.00%), Query Frame = 1

Query:  349 MATESTRIDNEICFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            MATESTRIDNEICFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSS+KMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKW+INKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLNNHCNNKPNNNEVIELNLNSTDIPKIKYIKKKPVAPVAWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYI++
Sbjct:    1 MATESTRIDNEICFSKSSYDNFVDLFGNLFLNFSLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKVIIPHCNIIKLNSPSHSKCNLSSVKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWMINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLNNHCNNKPNNNEVIELNLNSTDIPKIKYIKKKPVAPVAWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYISL 399

HSP 2 Score: 102.449 bits (254), Expect = 5.358e-23
Identity = 51/51 (100.00%), Postives = 51/51 (100.00%), Query Frame = 2

Query: 1541 MSEMNATLEDKDSVEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGDKISI 1693
            MSEMNATLEDKDSVEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGDKISI
Sbjct:  403 MSEMNATLEDKDSVEVVEFGIFKTFIIQNIGLLMGYSILLLMALYGDKISI 453

[Close]

BLAST of slc39a-12 vs. Planmine SMEST
Match: SMESG000016191.1 (SMESG000016191.1)

HSP 1 Score: 273.092 bits (697), Expect = 2.176e-85
Identity = 157/382 (41.10%), Postives = 233/382 (60.99%), Query Frame = 1

Query:  433 LFLNFSLQNAGDLMKNKLSKANFSTEC-----LARRFVNSTPELQKSTFEGLIAM---IVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEV---IELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            LF NF ++   D  K    K N + +C        +F NS  E+     +GL      I+ +++   C  +  +  S      S L++W+YG ++VT+ N  A LGI FIPLM KK Y  +MTFM+SLA+G+L G+++LILIPD+MQ++E+       +  YK+KAT V  G+Y+FFL ER LK + N++        + SH + +    P  K EI ++ + + +    + + +L         + E     ++  +           KK +APVAWM++FGD+LHN +DG+SIGA FS + + G+S+S+AV+CEELPHELGDFA+LL AGM++KQA+ WN++SA TCY+GFIIGVI+G+ TS S W+FA AGGMFLYI++
Sbjct:   42 LFDNFKIKT--DYWKASFGKRNITEKCGPVISYLNKFSNSVVEINNE--KGLKTFNNYILSRLLNNPCGALTTSKESQK---FSVLQIWIYGLLTVTVNNVLAILGIFFIPLMKKKIYNSVMTFMVSLAIGALAGTSILILIPDSMQISEIALKAKHDKNDYKWKATGVVAGLYLFFLTERLLKSLTNQK--------TCSHATAH----PVMKFEIMKLENSDRIQSRTQTENSLLQQMKLNDKDQEKGNDCDVKNSKAKEIIHLDKTKKGIAPVAWMVVFGDSLHNLVDGMSIGAGFSQSVILGVSISLAVLCEELPHELGDFAVLLTAGMSVKQAVFWNLMSAMTCYLGFIIGVIVGDITSASVWIFAFAGGMFLYISL 404

[Close]

BLAST of slc39a-12 vs. Planmine SMEST
Match: SMESG000016191.1 (SMESG000016191.1)

HSP 1 Score: 272.707 bits (696), Expect = 3.089e-85
Identity = 157/382 (41.10%), Postives = 233/382 (60.99%), Query Frame = 1

Query:  433 LFLNFSLQNAGDLMKNKLSKANFSTEC-----LARRFVNSTPELQKSTFEGLIAM---IVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQINSDNHLIVAPEMKTTLXXXXXXXXXXXEV---IELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            LF NF ++   D  K    K N + +C        +F NS  E+     +GL      I+ +++   C  +  +  S      S L++W+YG ++VT+ N  A LGI FIPLM KK Y  +MTFM+SLA+G+L G+++LILIPD+MQ++E+       +  YK+KAT V  G+Y+FFL ER LK + N++        + SH + +    P  K EI ++ + + +    + + +L         + E     ++  +           KK +APVAWM++FGD+LHN +DG+SIGA FS + + G+S+S+AV+CEELPHELGDFA+LL AGM++KQA+ WN++SA TCY+GFIIGVI+G+ TS S W+FA AGGMFLYI++
Sbjct:   45 LFDNFKIKT--DYWKASFGKRNITEKCGPVISYLNKFSNSVVEINNE--KGLKTFNNYILSRLLNNPCGALTTSKESQK---FSVLQIWIYGLLTVTVNNVLAILGIFFIPLMKKKIYNSVMTFMVSLAIGALAGTSILILIPDSMQISEIALKAKHDKNDYKWKATGVVAGLYLFFLTERLLKSLTNQK--------TCSHATAH----PVMKFEIMKLENSDRIQSRTQTENSLLQQMKLNDKDQEKGNDCDVKNSKAKEIIHLDKTKKGIAPVAWMVVFGDSLHNLVDGMSIGAGFSQSVILGVSISLAVLCEELPHELGDFAVLLTAGMSVKQAVFWNLMSAMTCYLGFIIGVIVGDITSASVWIFAFAGGMFLYISL 407

[Close]

BLAST of slc39a-12 vs. Planmine SMEST
Match: SMESG000016191.1 (SMESG000016191.1)

HSP 1 Score: 271.552 bits (693), Expect = 7.075e-85
Identity = 159/380 (41.84%), Postives = 231/380 (60.79%), Query Frame = 1

Query:  433 LFLNFSLQNAGDLMKNKLSKANFSTEC-----LARRFVNSTPELQKSTFEGLIAM---IVDKVIIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLMNKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYKYKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKPKLEIDQI-NSDNHLIVAPEMKTTLXXXXXXXXXXXEVIELNLNSTDXXXXXXXXXXXXXXXXWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICEELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGSTWVFAVAGGMFLYINV 1545
            LF NF ++   D  K    K N + +C        +F NS  E+     +GL      I+ +++   C  +  +  S      S L++W+YG ++VT+ N  A LGI FIPLM KK Y  +MTFM+SLA+G+L G+++LILIPD+MQ++E+       +  YK+KAT V  G+Y+FFL ER LK + N++        + SH + +    P  K EI ++ NSD    +    +T      +         ++  +           KK +APVAWM++FGD+LHN +DG+SIGA FS + + G+S+S+AV+CEELPHELGDFA+LL AGM++KQA+ WN++SA TCY+GFIIGVI+G+ TS S W+FA AGGMFLYI++
Sbjct:   42 LFDNFKIKT--DYWKASFGKRNITEKCGPVISYLNKFSNSVVEINNE--KGLKTFNNYILSRLLNNPCGALTTSKESQK---FSVLQIWIYGLLTVTVNNVLAILGIFFIPLMKKKIYNSVMTFMVSLAIGALAGTSILILIPDSMQISEIALKAKHDKNDYKWKATGVVAGLYLFFLTERLLKSLTNQK--------TCSHATAH----PVMKFEIMKLENSDR---IQSRTQTEQMKLNDKDQEKGNDCDVKNSKAKEIIHLDKTKKGIAPVAWMVVFGDSLHNLVDGMSIGAGFSQSVILGVSISLAVLCEELPHELGDFAVLLTAGMSVKQAVFWNLMSAMTCYLGFIIGVIVGDITSASVWIFAFAGGMFLYISL 399

The following BLAST results are available for this feature:

BLAST of slc39a-12 vs. Ensembl Human
BLAST of slc39a-12 vs. Ensembl Celegans
BLAST of slc39a-12 vs. Ensembl Fly
BLAST of slc39a-12 vs. Ensembl Zebrafish
BLAST of slc39a-12 vs. Ensembl Xenopus
BLAST of slc39a-12 vs. Ensembl Mouse
BLAST of slc39a-12 vs. UniProt/SwissProt
BLAST of slc39a-12 vs. TrEMBL
BLAST of slc39a-12 vs. Ensembl Cavefish
BLAST of slc39a-12 vs. Ensembl Sea Lamprey
BLAST of slc39a-12 vs. Ensembl Yeast
BLAST of slc39a-12 vs. Ensembl Nematostella
BLAST of slc39a-12 vs. Ensembl Medaka
BLAST of slc39a-12 vs. Planmine SMEST

BLAST of slc39a-12 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC39A14	2.052e-57	37.87	solute carrier family 39 member 14 [Source:HGNC Sy...	[more]
SLC39A14	3.110e-57	37.87	solute carrier family 39 member 14 [Source:HGNC Sy...	[more]
SLC39A14	3.110e-57	37.87	solute carrier family 39 member 14 [Source:HGNC Sy...	[more]
SLC39A14	9.893e-56	36.88	solute carrier family 39 member 14 [Source:HGNC Sy...	[more]
SLC39A8	2.750e-48	35.86	solute carrier family 39 member 8 [Source:HGNC Sym...	[more]

BLAST of slc39a-12 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
zipt-15	6.542e-51	37.78	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]
zipt-15	8.738e-40	38.31	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]
zipt-17	7.070e-24	46.08	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]
zipt-16	1.313e-23	45.19	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]
zipt-16	1.468e-23	45.19	Zrt (ZRT), Irt-(IRT-) like Protein Transporter [S...	[more]

BLAST of slc39a-12 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
foi	1.367e-32	55.34	gene:FBgn0024236 transcript:FBtr0331418	[more]
foi	1.367e-32	55.34	gene:FBgn0024236 transcript:FBtr0345601	[more]
foi	1.367e-32	55.34	gene:FBgn0024236 transcript:FBtr0331417	[more]
foi	1.367e-32	55.34	gene:FBgn0024236 transcript:FBtr0076624	[more]
Zip71B	1.733e-24	45.19	gene:FBgn0036461 transcript:FBtr0113171	[more]

BLAST of slc39a-12 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc39a14	1.238e-54	31.41	solute carrier family 39 member 14 [Source:NCBI ge...	[more]
slc39a14	1.238e-54	31.41	solute carrier family 39 member 14 [Source:NCBI ge...	[more]
slc39a14	5.556e-52	30.10	solute carrier family 39 member 14 [Source:NCBI ge...	[more]
LO018202.1	6.792e-47	32.56	pep chromosome:GRCz11:14:50034196:50059783:1 gene:...	[more]
slc39a10	9.841e-37	59.62	solute carrier family 39 member 10 [Source:NCBI ge...	[more]

BLAST of slc39a-12 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc8a2	6.170e-58	34.40	solute carrier family 8 member A2 [Source:Xenbase;...	[more]
slc8a2	7.058e-58	33.60	solute carrier family 8 member A2 [Source:Xenbase;...	[more]
SLC39A8	7.008e-56	34.90	solute carrier family 39 (zinc transporter), membe...	[more]
tmem135	3.608e-42	29.06	transmembrane protein 135 [Source:Xenbase;Acc:XB-G...	[more]
tmem135	7.439e-42	29.06	transmembrane protein 135 [Source:Xenbase;Acc:XB-G...	[more]

BLAST of slc39a-12 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Slc39a14	1.169e-58	34.44	solute carrier family 39 (zinc transporter), membe...	[more]
Slc39a14	1.992e-56	33.61	solute carrier family 39 (zinc transporter), membe...	[more]
Slc39a14	1.992e-56	33.61	solute carrier family 39 (zinc transporter), membe...	[more]
Slc39a8	1.039e-53	33.77	solute carrier family 39 (metal ion transporter), ...	[more]
Slc39a8	1.039e-53	33.77	solute carrier family 39 (metal ion transporter), ...	[more]

BLAST of slc39a-12 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q75N73\|S39AE_MOUSE	8.180e-58	34.44	Metal cation symporter ZIP14 OS=Mus musculus OX=10...	[more]
sp\|A4IGY6\|S39AE_XENTR	2.696e-57	34.40	Metal cation symporter ZIP14 OS=Xenopus tropicalis...	[more]
sp\|A5D7L5\|S39AE_BOVIN	8.898e-57	38.54	Metal cation symporter ZIP14 OS=Bos taurus OX=9913...	[more]
sp\|Q15043\|S39AE_HUMAN	1.493e-56	37.87	Metal cation symporter ZIP14 OS=Homo sapiens OX=96...	[more]
sp\|Q5RAB7\|S39AE_PONAB	5.030e-56	37.54	Metal cation symporter ZIP14 OS=Pongo abelii OX=96...	[more]

BLAST of slc39a-12 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0H3YFM2	0.000e+0	100.00	Slc39a-12 OS=Schmidtea mediterranea OX=79327 GN=sl...	[more]
A0A0H3YJE9	1.111e-81	41.10	Slc39a-1 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
A0A0L8G579	2.935e-72	44.87	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]
A0A1I8I022	1.152e-69	39.03	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8GYN7	1.387e-69	36.83	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]

BLAST of slc39a-12 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc39a14	1.800e-56	36.56	solute carrier family 39 member 14 [Source:NCBI ge...	[more]
ENSAMXT00000003334.2	1.162e-51	35.84	zinc transporter ZIP8-like [Source:NCBI gene;Acc:1...	[more]
ENSAMXT00000004885.2	1.581e-39	30.46	zinc transporter ZIP4 [Source:NCBI gene;Acc:103045...	[more]
slc39a8	1.635e-39	30.30	zinc transporter ZIP8 [Source:NCBI gene;Acc:103035...	[more]
ENSAMXT00000045640.1	2.223e-39	30.46	zinc transporter ZIP4 [Source:NCBI gene;Acc:103045...	[more]

BLAST of slc39a-12 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
slc39a14	1.454e-61	41.16	solute carrier family 39 member 14 [Source:NCBI ge...	[more]
ENSPMAT00000000371.1	4.133e-38	59.62	pep scaffold:Pmarinus_7.0:GL476519:142118:151022:-...	[more]
SLC39A12	2.043e-36	26.63	solute carrier family 39 member 12 [Source:HGNC Sy...	[more]
ENSPMAT00000009266.1	2.881e-26	49.06	pep scaffold:Pmarinus_7.0:GL483721:1641:4019:1 gen...	[more]

BLAST of slc39a-12 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
YKE4	5.455e-11	41.33	Zinc transporter; localizes to the ER; null mutant...	[more]

BLAST of slc39a-12 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO37361	8.561e-38	56.86	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29311	8.677e-35	51.43	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47899	2.087e-34	50.48	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47900	1.093e-33	56.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49001	1.304e-32	58.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of slc39a-12 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc39a14	1.275e-54	38.57	solute carrier family 39 member 14 [Source:NCBI ge...	[more]
slc39a14	5.599e-54	36.89	solute carrier family 39 member 14 [Source:NCBI ge...	[more]
slc39a8	5.404e-53	35.38	solute carrier family 39 member 8 [Source:NCBI gen...	[more]
slc39a8	1.340e-52	35.38	solute carrier family 39 member 8 [Source:NCBI gen...	[more]
ENSORLT00000030843.1	1.460e-39	29.62	solute carrier family 39 member 4 [Source:NCBI gen...	[more]

BLAST of slc39a-12 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000016243.1	6.829e-23	98.80	SMESG000016243.1	[more]
SMESG000016243.1	5.358e-23	99.00	SMESG000016243.1	[more]
SMESG000016191.1	2.176e-85	41.10	SMESG000016191.1	[more]
SMESG000016191.1	3.089e-85	41.10	SMESG000016191.1	[more]
SMESG000016191.1	7.075e-85	41.84	SMESG000016191.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30005645
GenBank	AKN21677.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30005645 ID=SMED30005645|Name=slc39a-12|organism=Schmidtea mediterranea sexual|type=transcript|length=1694bp
TTAGCATTTCCAGGTATATGCTAAGTATATGCTAATAAATGAAATGATAA
ATAACATTATTTCCCTCATTTTATTAGAATTGTTTGTATTGTAATTTATT
AAAAATGTAATTAAAAGTTGACGATTAATTTGCCGTCAAAAAGTGCTAAT
TATAAATCTCAAGGTAAAGTAAACCGGCTTGTTTTAATTTACTAATACTA
TGATAAGAGCCAAATGAATTTCGAAAAATTTTGACTATAATTATCTATTA
ATTTTTTATCGTTCATATCATAATAATCATCCCAAATTCAATTACCAATG
AGACATTTTTCGTTTGTCGATTTGTTAGCATTTTTTATCAGTTTATTAAT
GGCTACAGAATCCACAAGAATCGACAATGAGATTTGTTTCTCAAAATCTT
CTTATGATAATTTCGTTGATCTTTTCGGAAATTTGTTTCTGAATTTTTCG
TTGCAAAATGCTGGAGATTTGATGAAAAATAAATTGTCAAAGGCTAATTT
TTCGACTGAATGCTTGGCTAGAAGATTCGTCAACTCGACTCCGGAATTAC
AGAAAAGCACATTTGAAGGTCTTATAGCCATGATTGTTGACAAAGTCATA
ATTCCTCATTGCAATATTATCAAACTGAATTCTCCCAGCCATTCTAAGTG
CAATTTATCTTCTCTTAAAATGTGGGTTTACGGATTTATTTCTGTCACCA
TTATCAATGCCTGTGCCGGCCTCGGGATCCTCTTCATTCCTTTGATGAAT
AAGAAGTTTTATAAAGTTTTAATGACATTTATGATATCATTAGCAGTTGG
ATCATTAACTGGCAGCGCCTTGCTGATTTTAATTCCCGATGCAATGCAAC
TGGCGGAACTCCAGCACGGATATCCGGGATATCAAGTGAGCTATAAATAC
AAAGCTACTGTCGTATTCGGAGGAGTGTATATGTTTTTTCTGTTGGAAAG
GTTTCTGAAGTGGATTATCAATAAAGAAGTGAGGACGTTCAACCGGGCCA
ACTCTCTCAGTCACGGCTCACTGAATATCTCGAGAACGCCGAAACCGAAA
TTGGAAATCGACCAAATAAATTCAGACAATCATTTGATAGTTGCACCAGA
GATGAAAACGACACTAAATAATCATTGCAACAATAAGCCTAATAACAATG
AAGTGATTGAACTCAATCTCAATTCAACGGACATTCCAAAGATAAAATAT
ATCAAAAAAAAACCGGTTGCCCCAGTCGCCTGGATGATAATATTTGGAGA
TGCCCTCCATAACTTTATAGATGGGCTGTCTATTGGAGCCGCGTTCTCCC
ATAATACAATGACAGGAATCAGTCTTTCAATTGCCGTCATATGTGAAGAA
CTCCCCCATGAACTCGGAGATTTCGCGATACTTTTGAATGCGGGAATGAA
TATCAAGCAAGCTTTGATGTGGAACATGCTGTCGGCCGCTACCTGTTATA
TTGGGTTTATTATTGGGGTTATTTTGGGGGAGACAACATCAGGATCAACT
TGGGTGTTTGCGGTTGCTGGAGGAATGTTTCTCTATATCAATGTCTGAAA
TGAATGCAACTCTGGAAGATAAAGATAGTGTAGAAGTTGTCGAGTTCGGA
ATCTTCAAGACATTCATCATCCAGAATATTGGGCTTTTGATGGGATACTC
TATATTGCTTTTGATGGCTTTGTATGGGGATAAGATCAGCATCA

protein sequence of SMED30005645-orf-1

>SMED30005645-orf-1 ID=SMED30005645-orf-1|Name=SMED30005645-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=417bp
MRHFSFVDLLAFFISLLMATESTRIDNEICFSKSSYDNFVDLFGNLFLNF
SLQNAGDLMKNKLSKANFSTECLARRFVNSTPELQKSTFEGLIAMIVDKV
IIPHCNIIKLNSPSHSKCNLSSLKMWVYGFISVTIINACAGLGILFIPLM
NKKFYKVLMTFMISLAVGSLTGSALLILIPDAMQLAELQHGYPGYQVSYK
YKATVVFGGVYMFFLLERFLKWIINKEVRTFNRANSLSHGSLNISRTPKP
KLEIDQINSDNHLIVAPEMKTTLNNHCNNKPNNNEVIELNLNSTDIPKIK
YIKKKPVAPVAWMIIFGDALHNFIDGLSIGAAFSHNTMTGISLSIAVICE
ELPHELGDFAILLNAGMNIKQALMWNMLSAATCYIGFIIGVILGETTSGS
TWVFAVAGGMFLYINV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002089	reproductive organ
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR003689	ZIP

Vocabulary: **biological process**
Term	Definition
GO:0055085	transmembrane transport
GO:0030001	metal ion transport

Vocabulary: **molecular function**
Term	Definition
GO:0046873	metal ion transmembrane transporter activity

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003689	Zinc/iron permease	PFAM	PF02535	Zip	coord: 124..414 e-value: 1.7E-54 score: 185.3
None	No IPR available	PANTHER	PTHR12191	SOLUTE CARRIER FAMILY 39	coord: 78..414
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..19 score: 0.773
None	No IPR available	TMHMM	TMhelix		coord: 194..216
None	No IPR available	TMHMM	TMhelix		coord: 128..150
None	No IPR available	TMHMM	TMhelix		coord: 372..394
None	No IPR available	TMHMM	TMhelix		coord: 157..179
None	No IPR available	TMHMM	TMhelix		coord: 399..416