Phosphatidylinositol 4 phosphate 5 kinase type 1
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30005638 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Human
Match: PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [Source:HGNC Symbol;Acc:HGNC:8994]) HSP 1 Score: 350.903 bits (899), Expect = 4.101e-109 Identity = 165/275 (60.00%), Postives = 209/275 (76.00%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLR 962
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L EL ++GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ KP PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R
Sbjct: 51 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQR 325 HSP 2 Score: 56.9954 bits (136), Expect = 1.558e-7 Identity = 38/121 (31.40%), Postives = 53/121 (43.80%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIP 2120
RE + + S TRR A +ST +ESIQ + +D++++ KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP
Sbjct: 325 REPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETDDQFV-------------------------------KKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIP 414
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Human
Match: PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [Source:HGNC Symbol;Acc:HGNC:8994]) HSP 1 Score: 348.977 bits (894), Expect = 9.897e-109 Identity = 165/275 (60.00%), Postives = 209/275 (76.00%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLR 962
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L EL ++GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ KP PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R
Sbjct: 50 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQR 324 HSP 2 Score: 113.235 bits (282), Expect = 1.732e-25 Identity = 62/131 (47.33%), Postives = 81/131 (61.83%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPS--LDQPQIL 2144
RE + + S TRR A +ST +ESIQ + +D+ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP L +P +L
Sbjct: 324 REPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETDDH---MGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPCVHLGRPDVL 451
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Human
Match: PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [Source:HGNC Symbol;Acc:HGNC:8994]) HSP 1 Score: 350.903 bits (899), Expect = 1.000e-108 Identity = 165/275 (60.00%), Postives = 209/275 (76.00%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLR 962
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L EL ++GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ KP PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R
Sbjct: 51 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQR 325 HSP 2 Score: 111.694 bits (278), Expect = 9.691e-25 Identity = 59/121 (48.76%), Postives = 76/121 (62.81%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIP 2120
RE + + S TRR A +ST +ESIQ + +D+ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP
Sbjct: 325 REPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETDDH---MGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIP 442
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Human
Match: PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [Source:HGNC Symbol;Acc:HGNC:8994]) HSP 1 Score: 350.132 bits (897), Expect = 1.399e-108 Identity = 165/275 (60.00%), Postives = 209/275 (76.00%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLR 962
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L EL ++GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ KP PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R
Sbjct: 50 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQR 324 HSP 2 Score: 111.309 bits (277), Expect = 1.081e-24 Identity = 59/121 (48.76%), Postives = 76/121 (62.81%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIP 2120
RE + + S TRR A +ST +ESIQ + +D+ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP
Sbjct: 324 REPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETDDH---MGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIP 441
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Human
Match: PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [Source:HGNC Symbol;Acc:HGNC:8994]) HSP 1 Score: 350.517 bits (898), Expect = 1.920e-108 Identity = 165/275 (60.00%), Postives = 209/275 (76.00%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLR 962
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L EL ++GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ KP PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R
Sbjct: 63 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQR 337 HSP 2 Score: 111.309 bits (277), Expect = 1.191e-24 Identity = 59/121 (48.76%), Postives = 76/121 (62.81%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIP 2120
RE + + S TRR A +ST +ESIQ + +D+ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP
Sbjct: 337 REPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETDDH---MGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIP 454
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Celegans
Match: ppk-1 (PIP Kinase [Source:UniProtKB/TrEMBL;Acc:O01759]) HSP 1 Score: 367.081 bits (941), Expect = 1.328e-114 Identity = 166/285 (58.25%), Postives = 221/285 (77.54%), Query Frame = 3
Query: 135 KSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQE 986
K K+GHRRI+++G V+YKK T+ + +A+QLGI ++ + RD+LL+DF V+ + FP G TPSH DF F+T+APIAFRYFR+ F + D+L SIC + L+ELSNAGASGSIFY++ DD+FIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKF+GL+CYQ++GKNIR ++MNNL+P ++ +HEKYD+KGSTYKR AN+ E+ KP PTLKDLDF +NH + ++++ EALM +I RDC V+ESF IMDYSLL+GIHN++ ++ R E +E
Sbjct: 64 KEKLGHRRIDEQGGVSYKKVPTNALMQAIQLGISNSIGSLASLPNRDVLLQDFEKVDIVAFPAAGSTITPSHSFGDFRFRTYAPIAFRYFRNLFHIKPADFLRSICTEPLKELSNAGASGSIFYVSQDDQFIIKTVQHKEADFLQKLLPGYYMNLNQNPRTLLPKFFGLFCYQSLGKNIRLLVMNNLLPQTVTMHEKYDMKGSTYKRMANKAERAKPHPTLKDLDFLENHKDGIFIDPTALEALMKSISRDCLVMESFKIMDYSLLVGIHNVELGIKERAEQNRE 348 HSP 2 Score: 103.99 bits (258), Expect = 1.506e-22 Identity = 47/78 (60.26%), Postives = 56/78 (71.79%), Query Frame = 3
Query: 1899 IPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQ 2132
+P GG+PARN GDRL+L++GIIDILQ+YR++KKMEH KAI D ISV NP FYA RF F VFKK +L Q
Sbjct: 385 VPHGGVPARNSNGDRLVLYLGIIDILQNYRLLKKMEHTWKAILHDGDTISVHNPNFYASRFLTFMTEKVFKKGTALKQ 462
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Celegans
Match: ppk-2 (PIP Kinase [Source:UniProtKB/TrEMBL;Acc:Q9BL73]) HSP 1 Score: 107.457 bits (267), Expect = 1.804e-24 Identity = 75/234 (32.05%), Postives = 122/234 (52.14%), Query Frame = 3
Query: 342 PSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELR-ELSNAGASGSI--FYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQ-HPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNL-----RMRKENEQEQKNHALSSP 1013
PSH + K + P FR R+ F VD +YL S+ E +L + A S F+I+ D +F+IK++ + + L +L Y+ +++ +TLLP++ GLY G ++M N+ +H K+DLKGST R+A++ EK K PTLKD DF + + L L + + L+ + D L +MDYSLL+GIH+ ++ R ++N +E + +P
Sbjct: 79 PSH----YKVKEYCPNVFRNLREQFGVDNFEYLRSLTSYEPEPDLLDGSAKDSTPRFFISYDKKFVIKSMDSEAVAELHSVLRNYHQYVVEKQGKTLLPQYLGLYRLTIEGSETYLIVMRNVFGRKYGVHTKFDLKGSTVSRAASDKEKAKDLPTLKDNDFLE-QNWKLNLPPEAGKLLIEMLTSDTEWLTRMHLMDYSLLVGIHDCERAAQEAANRPVEQNSEESGDELAPTP 307
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Celegans
Match: ppk-3 (PIP Kinase [Source:UniProtKB/TrEMBL;Acc:G5ED98]) HSP 1 Score: 69.3218 bits (168), Expect = 1.472e-11 Identity = 56/175 (32.00%), Postives = 84/175 (48.00%), Query Frame = 3
Query: 462 LRELSNA-------GASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYY----INLIQHPRTLLPKFYGL----YCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKN-HDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGI 938
+R LSN+ G SGS FY T DD F++K + E K P Y+ + + T L K YG+ Y +T + ++M L + + + +DLKGS R A+ T K+ L D +F K+ ++ LY+ + A+ I D L S IMDYSLL+G+
Sbjct: 1249 IRSLSNSTFWTPQGGKSGSFFYRTQDDRFVVKQMSRFEIQSFVKFAPNYFDYLTTSATESKLTTLCKVYGVFRIGYKSKTTTLKVDILVMEYLFYNHNVSQVWDLKGSLRNRLAS-TGKSANEMVLLDENFVKDLWNQQLYVLPHSKAAMNQAISNDSHFLSSQYIMDYSLLVGV 1422
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Fly
Match: PIP5K59B (gene:FBgn0034789 transcript:FBtr0071900) HSP 1 Score: 366.311 bits (939), Expect = 8.967e-113 Identity = 178/293 (60.75%), Postives = 220/293 (75.09%), Query Frame = 3
Query: 120 KVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTM-GKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQK 992
K KE+ KIGHRR+ + G +TYKK TS+I ++QLGI+ TV +K KRD+L+ DF +E++ FP G TP+H S+F +K +APIAFRYFRD F + D++ S+C LRELSN GASGSIFY+T DDEFIIKTVQHKE FLQKLLP YY+NL Q+PRTLLPKF+GLYC QT KNIR V+MNNL+P S+++H KYDLKGST+KR AN+ E+ K SPT KDLDF + H ++LE +TY AL+ TIQRDC VLESF IMDYSLLLG+HNLD L KE + EQ+
Sbjct: 52 KADKER-KIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVAL---KEKQSEQR 340 HSP 2 Score: 127.102 bits (318), Expect = 1.565e-29 Identity = 63/112 (56.25%), Postives = 83/112 (74.11%), Query Frame = 3
Query: 1794 SRSKST--RRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPS 2123
SR+KS +R+ A ST +ESIQA E ++ DEE +P GGIPAR++ G+RL+L++GIIDILQSYR+ KK+EH K+I D +SV P+FYAQRFQ+F A VF+KIPS
Sbjct: 368 SRNKSVNRQRLVAHSTAMESIQAESEPID----DEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFRKIPS 475
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Fly
Match: PIP5K59B (gene:FBgn0034789 transcript:FBtr0304923) HSP 1 Score: 366.311 bits (939), Expect = 1.716e-112 Identity = 178/293 (60.75%), Postives = 220/293 (75.09%), Query Frame = 3
Query: 120 KVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTM-GKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQK 992
K KE+ KIGHRR+ + G +TYKK TS+I ++QLGI+ TV +K KRD+L+ DF +E++ FP G TP+H S+F +K +APIAFRYFRD F + D++ S+C LRELSN GASGSIFY+T DDEFIIKTVQHKE FLQKLLP YY+NL Q+PRTLLPKF+GLYC QT KNIR V+MNNL+P S+++H KYDLKGST+KR AN+ E+ K SPT KDLDF + H ++LE +TY AL+ TIQRDC VLESF IMDYSLLLG+HNLD L KE + EQ+
Sbjct: 52 KADKER-KIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVAL---KEKQSEQR 340 HSP 2 Score: 127.102 bits (318), Expect = 1.740e-29 Identity = 63/112 (56.25%), Postives = 83/112 (74.11%), Query Frame = 3
Query: 1794 SRSKST--RRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPS 2123
SR+KS +R+ A ST +ESIQA E ++ DEE +P GGIPAR++ G+RL+L++GIIDILQSYR+ KK+EH K+I D +SV P+FYAQRFQ+F A VF+KIPS
Sbjct: 368 SRNKSVNRQRLVAHSTAMESIQAESEPID----DEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFRKIPS 475
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Fly
Match: PIP5K59B (gene:FBgn0034789 transcript:FBtr0290095) HSP 1 Score: 365.925 bits (938), Expect = 2.278e-112 Identity = 178/293 (60.75%), Postives = 220/293 (75.09%), Query Frame = 3
Query: 120 KVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTM-GKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQK 992
K KE+ KIGHRR+ + G +TYKK TS+I ++QLGI+ TV +K KRD+L+ DF +E++ FP G TP+H S+F +K +APIAFRYFRD F + D++ S+C LRELSN GASGSIFY+T DDEFIIKTVQHKE FLQKLLP YY+NL Q+PRTLLPKF+GLYC QT KNIR V+MNNL+P S+++H KYDLKGST+KR AN+ E+ K SPT KDLDF + H ++LE +TY AL+ TIQRDC VLESF IMDYSLLLG+HNLD L KE + EQ+
Sbjct: 52 KADKER-KIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVAL---KEKQSEQR 340 HSP 2 Score: 152.91 bits (385), Expect = 9.663e-38 Identity = 80/159 (50.31%), Postives = 113/159 (71.07%), Query Frame = 3
Query: 1794 SRSKST--RRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFV--HMAMRQNPDRKRTSSVRKENLIPSDKE 2258
SR+KS +R+ A ST +ESIQA E ++ DEE +P GGIPAR++ G+RL+L++GIIDILQSYR+ KK+EH K+I D +SV P+FYAQRFQ+F A VF+KIPSLD P+I G+H R+FR V ++A++ +P ++++ S + I SD E
Sbjct: 368 SRNKSVNRQRLVAHSTAMESIQAESEPID----DEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFRKIPSLDLPEIKGNH-RKFRTLVTSYIALKHSPSKRKSLSKAIQRSIDSDNE 521
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Fly
Match: PIP5K59B (gene:FBgn0034789 transcript:FBtr0304921) HSP 1 Score: 366.311 bits (939), Expect = 3.088e-112 Identity = 178/293 (60.75%), Postives = 220/293 (75.09%), Query Frame = 3
Query: 120 KVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTM-GKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQK 992
K KE+ KIGHRR+ + G +TYKK TS+I ++QLGI+ TV +K KRD+L+ DF +E++ FP G TP+H S+F +K +APIAFRYFRD F + D++ S+C LRELSN GASGSIFY+T DDEFIIKTVQHKE FLQKLLP YY+NL Q+PRTLLPKF+GLYC QT KNIR V+MNNL+P S+++H KYDLKGST+KR AN+ E+ K SPT KDLDF + H ++LE +TY AL+ TIQRDC VLESF IMDYSLLLG+HNLD L KE + EQ+
Sbjct: 52 KADKER-KIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVAL---KEKQSEQR 340 HSP 2 Score: 152.91 bits (385), Expect = 1.059e-37 Identity = 80/159 (50.31%), Postives = 113/159 (71.07%), Query Frame = 3
Query: 1794 SRSKST--RRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFV--HMAMRQNPDRKRTSSVRKENLIPSDKE 2258
SR+KS +R+ A ST +ESIQA E ++ DEE +P GGIPAR++ G+RL+L++GIIDILQSYR+ KK+EH K+I D +SV P+FYAQRFQ+F A VF+KIPSLD P+I G+H R+FR V ++A++ +P ++++ S + I SD E
Sbjct: 368 SRNKSVNRQRLVAHSTAMESIQAESEPID----DEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFRKIPSLDLPEIKGNH-RKFRTLVTSYIALKHSPSKRKSLSKAIQRSIDSDNE 521
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Fly
Match: PIP5K59B (gene:FBgn0034789 transcript:FBtr0339762) HSP 1 Score: 365.925 bits (938), Expect = 4.416e-112 Identity = 178/293 (60.75%), Postives = 220/293 (75.09%), Query Frame = 3
Query: 120 KVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTM-GKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQK 992
K KE+ KIGHRR+ + G +TYKK TS+I ++QLGI+ TV +K KRD+L+ DF +E++ FP G TP+H S+F +K +APIAFRYFRD F + D++ S+C LRELSN GASGSIFY+T DDEFIIKTVQHKE FLQKLLP YY+NL Q+PRTLLPKF+GLYC QT KNIR V+MNNL+P S+++H KYDLKGST+KR AN+ E+ K SPT KDLDF + H ++LE +TY AL+ TIQRDC VLESF IMDYSLLLG+HNLD L KE + EQ+
Sbjct: 52 KADKER-KIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVAL---KEKQSEQR 340 HSP 2 Score: 154.066 bits (388), Expect = 5.579e-38 Identity = 80/163 (49.08%), Postives = 113/163 (69.33%), Query Frame = 3
Query: 1776 SFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFV--HMAMRQNPDRKRTSSVRKENLIPSDKE 2258
S N RS + +R+ A ST +ESIQA E ++ DEE +P GGIPAR++ G+RL+L++GIIDILQSYR+ KK+EH K+I D +SV P+FYAQRFQ+F A VF+KIPSLD P+I G+H R+FR V ++A++ +P ++++ S + I SD E
Sbjct: 368 SRNNAAYRSVNRQRLVAHSTAMESIQAESEPID----DEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFRKIPSLDLPEIKGNH-RKFRTLVTSYIALKHSPSKRKSLSKAIQRSIDSDNE 525
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Zebrafish
Match: pip5k1cb (phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b [Source:ZFIN;Acc:ZDB-GENE-110408-21]) HSP 1 Score: 357.451 bits (916), Expect = 1.092e-109 Identity = 169/278 (60.79%), Postives = 215/278 (77.34%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSI-RIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK 971
KIGHRR++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGSIFY+T DDEFI+KTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P + R+H K+DLKGSTYKR A++ E+ K PT KDLDF ++ + L L+VDTY AL+ T+QRDC VLESF IMDYSLLLG+HN++Q R R+
Sbjct: 55 KIGHRRVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSIFYVTRDDEFILKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRIVVMNNVLPRVFRMHLKFDLKGSTYKRRASKKEREKNRPTYKDLDFMQDVQDGLLLDVDTYNALLKTLQRDCLVLESFKIMDYSLLLGVHNVEQAERERQ 332 HSP 2 Score: 92.8189 bits (229), Expect = 1.034e-18 Identity = 50/102 (49.02%), Postives = 65/102 (63.73%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSL 2126
A +ST +ESIQ + +D+ GGIPA + G+RL+LF+GIIDILQSYR++KK+EH KA+ D +SV P FYA RF F + VFKK SL
Sbjct: 349 ALYSTAMESIQGGAACGDSIDTDDT---MGGIPAVSGKGERLLLFIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPNFYADRFFRFMSANVFKKSTSL 447
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Zebrafish
Match: pip5k1ca (phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a [Source:ZFIN;Acc:ZDB-GENE-050208-358]) HSP 1 Score: 354.369 bits (908), Expect = 3.188e-109 Identity = 170/286 (59.44%), Postives = 215/286 (75.17%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKN 995
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF + + L L+ DTY AL+ T+QRDC VLESF IMDYSLLLG+HN+DQ + ++ E Q N
Sbjct: 62 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRMVVMNNVLPRVVRMHLKYDLKGSTYKRRASKKEREKAKPTFKDLDFMQELPDGLMLDTDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQAAK-EQQMEGSQGN 346 HSP 2 Score: 97.0561 bits (240), Expect = 4.092e-20 Identity = 57/144 (39.58%), Postives = 82/144 (56.94%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSS----VRKENL 2240
A ++T +ESIQ E +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA RF F ++ VF+K SL S +R R + + P ++S +R EN+
Sbjct: 357 ALYTTAMESIQGASACGEGIDTDDT---MGGIPAVNGRGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYADRFLRFMSSTVFRKTSSLKS-----SPSKRGRGGLAVGKYCGPGAAWSASQLPFMRDENI 492
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Zebrafish
Match: pip5k1ca (phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a [Source:ZFIN;Acc:ZDB-GENE-050208-358]) HSP 1 Score: 354.755 bits (909), Expect = 3.192e-109 Identity = 170/286 (59.44%), Postives = 215/286 (75.17%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKN 995
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF + + L L+ DTY AL+ T+QRDC VLESF IMDYSLLLG+HN+DQ + ++ E Q N
Sbjct: 62 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRMVVMNNVLPRVVRMHLKYDLKGSTYKRRASKKEREKAKPTFKDLDFMQELPDGLMLDTDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQAAK-EQQMEGSQGN 346 HSP 2 Score: 97.0561 bits (240), Expect = 4.427e-20 Identity = 57/144 (39.58%), Postives = 82/144 (56.94%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSS----VRKENL 2240
A ++T +ESIQ E +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA RF F ++ VF+K SL S +R R + + P ++S +R EN+
Sbjct: 357 ALYTTAMESIQGASACGEGIDTDDT---MGGIPAVNGRGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYADRFLRFMSSTVFRKTSSLKS-----SPSKRGRGGLAVGKYCGPGAAWSASQLPFMRDENI 492
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Zebrafish
Match: pip5k1ca (phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a [Source:ZFIN;Acc:ZDB-GENE-050208-358]) HSP 1 Score: 355.14 bits (910), Expect = 4.877e-109 Identity = 170/286 (59.44%), Postives = 215/286 (75.17%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKN 995
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF + + L L+ DTY AL+ T+QRDC VLESF IMDYSLLLG+HN+DQ + ++ E Q N
Sbjct: 62 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRMVVMNNVLPRVVRMHLKYDLKGSTYKRRASKKEREKAKPTFKDLDFMQELPDGLMLDTDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQAAK-EQQMEGSQGN 346 HSP 2 Score: 97.0561 bits (240), Expect = 4.775e-20 Identity = 57/144 (39.58%), Postives = 82/144 (56.94%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSS----VRKENL 2240
A ++T +ESIQ E +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA RF F ++ VF+K SL S +R R + + P ++S +R EN+
Sbjct: 357 ALYTTAMESIQGASACGEGIDTDDT---MGGIPAVNGRGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYADRFLRFMSSTVFRKTSSLKS-----SPSKRGRGGLAVGKYCGPGAAWSASQLPFMRDENI 492
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Zebrafish
Match: pip5k1ca (phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a [Source:ZFIN;Acc:ZDB-GENE-050208-358]) HSP 1 Score: 355.14 bits (910), Expect = 5.115e-109 Identity = 170/286 (59.44%), Postives = 215/286 (75.17%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKN 995
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF + + L L+ DTY AL+ T+QRDC VLESF IMDYSLLLG+HN+DQ + ++ E Q N
Sbjct: 62 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRMVVMNNVLPRVVRMHLKYDLKGSTYKRRASKKEREKAKPTFKDLDFMQELPDGLMLDTDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQAAK-EQQMEGSQGN 346 HSP 2 Score: 97.0561 bits (240), Expect = 4.560e-20 Identity = 57/144 (39.58%), Postives = 82/144 (56.94%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSS----VRKENL 2240
A ++T +ESIQ E +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA RF F ++ VF+K SL S +R R + + P ++S +R EN+
Sbjct: 357 ALYTTAMESIQGASACGEGIDTDDT---MGGIPAVNGRGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYADRFLRFMSSTVFRKTSSLKS-----SPSKRGRGGLAVGKYCGPGAAWSASQLPFMRDENI 492
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Xenopus
Match: PIP5K1B (phosphatidylinositol-4-phosphate 5-kinase, type I, beta [Source:NCBI gene;Acc:100380056]) HSP 1 Score: 336.65 bits (862), Expect = 4.208e-105 Identity = 168/287 (58.54%), Postives = 210/287 (73.17%), Query Frame = 3
Query: 171 GTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVK 1028
G TYKK T+S I+ +QLGI TV +K RD+L++DF VVE++ P G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C + L ELSN GASGSIF++T DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q+ G NIR V+MNN++P S+R++ KYDLKGSTYKR A+ E+ K SPT KDLDF ++ E LY + +TY ALM T+QRDCRVLESF IMDYSLLLG+H L KE E E ++++ + +V+
Sbjct: 17 GEKTYKKTTSSAIKGTIQLGIGYTVGNLTSKPDRDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSLCSEPLIELSNPGASGSIFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGINIRIVVMNNVLPRSVRMNYKYDLKGSTYKRRASRKEREKSSPTYKDLDFLQDTPEGLYFDPETYSALMKTLQRDCRVLESFKIMDYSLLLGVHVLGST---SKEKEGESSHYSIDNKRPSVQ 300 HSP 2 Score: 103.219 bits (256), Expect = 1.579e-22 Identity = 51/97 (52.58%), Postives = 67/97 (69.07%), Query Frame = 3
Query: 1827 FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKI 2117
+ST LESIQ P + V+ + GGIPA+N G+R++LFMGIIDILQSYR+MKK+EH+ KA+ D ++SV P+FYA RF F VFKK+
Sbjct: 304 YSTALESIQGPGKDVDSFIKEST---MGGIPAKNHRGERMLLFMGIIDILQSYRLMKKLEHSWKALVYDGDSVSVHRPSFYADRFLKFMNARVFKKV 397
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Xenopus
Match: pip5k1c (phosphatidylinositol-4-phosphate 5-kinase, type I, gamma [Source:NCBI gene;Acc:100145583]) HSP 1 Score: 339.347 bits (869), Expect = 1.455e-104 Identity = 172/287 (59.93%), Postives = 215/287 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK-ENEQEQKN 995
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF E L L+ DT+ AL+ T+QRDC VLESF IMDYSLLLG+HN++Q R R+ E Q Q +
Sbjct: 27 KIGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVRMHFKYDLKGSTYKRRASKKEREKRCPTFKDLDFMNEAPEGLLLDNDTFNALVKTLQRDCLVLESFKIMDYSLLLGVHNMEQQERERQTEGAQSQAD 313 HSP 2 Score: 96.6709 bits (239), Expect = 4.571e-20 Identity = 50/113 (44.25%), Postives = 68/113 (60.18%), Query Frame = 3
Query: 1773 ESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFK 2111
E Q + + A +ST +ESIQ E +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA+RF F N VF+
Sbjct: 306 EGAQSQADEKRPVGQKALYSTAMESIQGGAAHGESIDTDDT---MGGIPAVNGKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFR 415
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Xenopus
Match: pip5k1c (phosphatidylinositol-4-phosphate 5-kinase, type I, gamma [Source:NCBI gene;Acc:100145583]) HSP 1 Score: 338.961 bits (868), Expect = 1.598e-104 Identity = 172/287 (59.93%), Postives = 215/287 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK-ENEQEQKN 995
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF E L L+ DT+ AL+ T+QRDC VLESF IMDYSLLLG+HN++Q R R+ E Q Q +
Sbjct: 27 KIGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVRMHFKYDLKGSTYKRRASKKEREKRCPTFKDLDFMNEAPEGLLLDNDTFNALVKTLQRDCLVLESFKIMDYSLLLGVHNMEQQERERQTEGAQSQAD 313 HSP 2 Score: 97.0561 bits (240), Expect = 4.155e-20 Identity = 50/113 (44.25%), Postives = 68/113 (60.18%), Query Frame = 3
Query: 1773 ESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFK 2111
E Q + + A +ST +ESIQ E +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA+RF F N VF+
Sbjct: 306 EGAQSQADEKRPVGQKALYSTAMESIQGGAAHGESIDTDDT---MGGIPAVNGKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFR 415
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Xenopus
Match: pip5k1c (phosphatidylinositol-4-phosphate 5-kinase, type I, gamma [Source:NCBI gene;Acc:100145583]) HSP 1 Score: 341.273 bits (874), Expect = 2.154e-104 Identity = 172/287 (59.93%), Postives = 215/287 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK-ENEQEQKN 995
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF E L L+ DT+ AL+ T+QRDC VLESF IMDYSLLLG+HN++Q R R+ E Q Q +
Sbjct: 51 KIGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVRMHFKYDLKGSTYKRRASKKEREKRCPTFKDLDFMNEAPEGLLLDNDTFNALVKTLQRDCLVLESFKIMDYSLLLGVHNMEQQERERQTEGAQSQAD 337 HSP 2 Score: 97.8265 bits (242), Expect = 3.176e-20 Identity = 50/113 (44.25%), Postives = 68/113 (60.18%), Query Frame = 3
Query: 1773 ESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFK 2111
E Q + + A +ST +ESIQ E +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA+RF F N VF+
Sbjct: 330 EGAQSQADEKRPVGQKALYSTAMESIQGGAAHGESIDTDDT---MGGIPAVNGKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFR 439
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Xenopus
Match: pip5k1c (phosphatidylinositol-4-phosphate 5-kinase, type I, gamma [Source:NCBI gene;Acc:100145583]) HSP 1 Score: 338.961 bits (868), Expect = 3.943e-104 Identity = 172/287 (59.93%), Postives = 215/287 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK-ENEQEQKN 995
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF E L L+ DT+ AL+ T+QRDC VLESF IMDYSLLLG+HN++Q R R+ E Q Q +
Sbjct: 27 KIGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVRMHFKYDLKGSTYKRRASKKEREKRCPTFKDLDFMNEAPEGLLLDNDTFNALVKTLQRDCLVLESFKIMDYSLLLGVHNMEQQERERQTEGAQSQAD 313 HSP 2 Score: 97.0561 bits (240), Expect = 4.570e-20 Identity = 50/113 (44.25%), Postives = 68/113 (60.18%), Query Frame = 3
Query: 1773 ESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFK 2111
E Q + + A +ST +ESIQ E +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA+RF F N VF+
Sbjct: 306 EGAQSQADEKRPVGQKALYSTAMESIQGGAAHGESIDTDDT---MGGIPAVNGKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMTNTVFR 415
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Mouse
Match: Pip5k1a (phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha [Source:MGI Symbol;Acc:MGI:107929]) HSP 1 Score: 351.673 bits (901), Expect = 6.922e-110 Identity = 167/283 (59.01%), Postives = 212/283 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQE 986
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L ELSN+GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R N+ +
Sbjct: 47 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQREPTSNDTQ 329 HSP 2 Score: 109.383 bits (272), Expect = 2.292e-24 Identity = 61/131 (46.56%), Postives = 80/131 (61.07%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIP--SLDQPQIL 2144
RE + S TRR A +ST +ESIQ + +++ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP L +P +L
Sbjct: 321 REPTSNDTQYSADTRRPAPQKALYSTAMESIQGEARRGGTVETEDH---MGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPYVHLGRPDVL 448
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Mouse
Match: Pip5k1a (phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha [Source:MGI Symbol;Acc:MGI:107929]) HSP 1 Score: 352.443 bits (903), Expect = 1.335e-109 Identity = 167/283 (59.01%), Postives = 212/283 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQE 986
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L ELSN+GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R N+ +
Sbjct: 47 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQREPTSNDTQ 329 HSP 2 Score: 112.079 bits (279), Expect = 5.090e-25 Identity = 74/196 (37.76%), Postives = 104/196 (53.06%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSP 2345
RE + S TRR A +ST +ESIQ + +++ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP P ++FR+ + R P +S L+ S + R +V ++E+ D +LG P+ P
Sbjct: 321 REPTSNDTQYSADTRRPAPQKALYSTAMESIQGEARRGGTVETEDH---MGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSP------TKKFRSGPSFSRRSGPSGNSCTS----QLMASGEHRA----QVTTKAEVEPD--VHLGRPDVLP 497
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Mouse
Match: Pip5k1a (phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha [Source:MGI Symbol;Acc:MGI:107929]) HSP 1 Score: 352.058 bits (902), Expect = 2.176e-109 Identity = 167/283 (59.01%), Postives = 212/283 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQE 986
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L ELSN+GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R N+ +
Sbjct: 48 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQREPTSNDTQ 330 HSP 2 Score: 112.079 bits (279), Expect = 5.082e-25 Identity = 74/196 (37.76%), Postives = 104/196 (53.06%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSP 2345
RE + S TRR A +ST +ESIQ + +++ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP P ++FR+ + R P +S L+ S + R +V ++E+ D +LG P+ P
Sbjct: 322 REPTSNDTQYSADTRRPAPQKALYSTAMESIQGEARRGGTVETEDH---MGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSP------TKKFRSGPSFSRRSGPSGNSCTS----QLMASGEHRA----QVTTKAEVEPD--VHLGRPDVLP 498
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Mouse
Match: Pip5k1a (phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha [Source:MGI Symbol;Acc:MGI:107929]) HSP 1 Score: 352.058 bits (902), Expect = 2.241e-109 Identity = 167/283 (59.01%), Postives = 212/283 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQE 986
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L ELSN+GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R N+ +
Sbjct: 49 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQREPTSNDTQ 331 HSP 2 Score: 112.079 bits (279), Expect = 5.119e-25 Identity = 74/196 (37.76%), Postives = 104/196 (53.06%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSP 2345
RE + S TRR A +ST +ESIQ + +++ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP P ++FR+ + R P +S L+ S + R +V ++E+ D +LG P+ P
Sbjct: 323 REPTSNDTQYSADTRRPAPQKALYSTAMESIQGEARRGGTVETEDH---MGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSP------TKKFRSGPSFSRRSGPSGNSCTS----QLMASGEHRA----QVTTKAEVEPD--VHLGRPDVLP 499
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Mouse
Match: Pip5k1b (phosphatidylinositol-4-phosphate 5-kinase, type 1 beta [Source:MGI Symbol;Acc:MGI:107930]) HSP 1 Score: 342.813 bits (878), Expect = 1.006e-106 Identity = 165/266 (62.03%), Postives = 205/266 (77.07%), Query Frame = 3
Query: 180 TYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKE 974
TYKK +S I+ A+QLGI TV +K +RD+L++DF VVE++ P G TP+H DF FKT+AP+AFRYFR+ F + DYL SIC + L ELSN GASGS+F++T DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q+ G NIR V+MNN++P ++R+H YDLKGSTYKR A+ E+ KP+PT KDLDF ++ E LY + +TY ALM T+QRDCRVLESF IMDYSLLLGIH LD +L+ ++E
Sbjct: 20 TYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFLTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHILDHSLKDKEE 285 HSP 2 Score: 101.293 bits (251), Expect = 8.690e-22 Identity = 56/115 (48.70%), Postives = 72/115 (62.61%), Query Frame = 3
Query: 1827 FSTVLESIQAPVEQ----VELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVR 2159
+ST +ESIQ P + + NP GGIPA++ G++L+LFMGIIDILQSYR+MKK+EH+ KA+ D +SV P+FYA RF F + VFKKI Q LGS R
Sbjct: 304 YSTAMESIQGPGKSADGIIAENPDT-----MGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKI------QALGSRHR 407
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. UniProt/SwissProt
Match: sp|P70182|PI51A_MOUSE (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha OS=Mus musculus OX=10090 GN=Pip5k1a PE=1 SV=2) HSP 1 Score: 352.058 bits (902), Expect = 1.522e-108 Identity = 167/283 (59.01%), Postives = 212/283 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQE 986
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L ELSN+GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R N+ +
Sbjct: 48 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQREPTSNDTQ 330 HSP 2 Score: 112.079 bits (279), Expect = 3.555e-24 Identity = 74/196 (37.76%), Postives = 104/196 (53.06%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSP 2345
RE + S TRR A +ST +ESIQ + +++ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP P ++FR+ + R P +S L+ S + R +V ++E+ D +LG P+ P
Sbjct: 322 REPTSNDTQYSADTRRPAPQKALYSTAMESIQGEARRGGTVETEDH---MGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSP------TKKFRSGPSFSRRSGPSGNSCTS----QLMASGEHRA----QVTTKAEVEPD--VHLGRPDVLP 498
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. UniProt/SwissProt
Match: sp|D3ZSI8|PI51A_RAT (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha OS=Rattus norvegicus OX=10116 GN=Pip5k1a PE=1 SV=1) HSP 1 Score: 351.288 bits (900), Expect = 2.215e-108 Identity = 166/275 (60.36%), Postives = 209/275 (76.00%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLR 962
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L ELSN+GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R
Sbjct: 47 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQR 321 HSP 2 Score: 112.849 bits (281), Expect = 1.634e-24 Identity = 64/148 (43.24%), Postives = 85/148 (57.43%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNP 2201
RE N + S TRR A +ST +ESIQ + +++ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP P ++FR+ + R P
Sbjct: 321 REPMNSETQYSIDTRRPAPQKALYSTAMESIQGEARRGGTVETEDH---MGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSP------TKKFRSGPSFSRRSGP 459
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. UniProt/SwissProt
Match: sp|Q99755|PI51A_HUMAN (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha OS=Homo sapiens OX=9606 GN=PIP5K1A PE=1 SV=1) HSP 1 Score: 350.517 bits (898), Expect = 9.221e-108 Identity = 165/275 (60.00%), Postives = 209/275 (76.00%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLR 962
KIGHR ++ G TYKK T+S ++ A+QLGI TV K +RD+L++DF VVE++ FP G TP+H +DF FKT+AP+AFRYFR+ F + DYL S+C + L EL ++GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q GKNIR V+MNNL+P S+++H KYDLKGSTYKR A++ E+ KP PT KDLDF ++ + L+L+ D Y AL T+QRDC VL+SF IMDYSLL+ IHN+D R
Sbjct: 63 KIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQR 337 HSP 2 Score: 111.309 bits (277), Expect = 5.721e-24 Identity = 59/121 (48.76%), Postives = 76/121 (62.81%), Query Frame = 3
Query: 1770 RESFNRQKSRSKSTRRIAA----FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIP 2120
RE + + S TRR A +ST +ESIQ + +D+ GGIPARN G+RL+L++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RFQ F N VFKKIP
Sbjct: 337 REPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETDDH---MGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIP 454
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. UniProt/SwissProt
Match: sp|Q5CZZ9|PI51B_RAT (Phosphatidylinositol 4-phosphate 5-kinase type-1 beta OS=Rattus norvegicus OX=10116 GN=Pip5k1b PE=1 SV=1) HSP 1 Score: 344.354 bits (882), Expect = 8.499e-106 Identity = 165/266 (62.03%), Postives = 205/266 (77.07%), Query Frame = 3
Query: 180 TYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKE 974
TYKK +S I+ A+QLGI TV +K +RD+L++DF VVE++ P G TP+H DF FKT+AP+AFRYFR+ F + DYL SIC + L ELSN GASGS+F++T DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q+ G NIR V+MNN++P ++R+H YDLKGSTYKR A+ E+ KP+PT KDLDF ++ E LY + +TY ALM T+QRDCRVLESF IMDYSLLLGIH LD +L+ ++E
Sbjct: 20 TYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFLTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHILDHSLKDKEE 285 HSP 2 Score: 101.679 bits (252), Expect = 6.290e-21 Identity = 52/104 (50.00%), Postives = 69/104 (66.35%), Query Frame = 3
Query: 1827 FSTVLESIQAPVEQ----VELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSL 2126
+ST +ESIQ P + + NP GGIPA++ G++L+LFMGIIDILQSYR+MKK+EH+ KA+ D +SV P+FYA RF F + VFKKI +L
Sbjct: 304 YSTAMESIQGPGKSADGIIAENPDT-----MGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQAL 402
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. UniProt/SwissProt
Match: sp|P70181|PI51B_MOUSE (Phosphatidylinositol 4-phosphate 5-kinase type-1 beta OS=Mus musculus OX=10090 GN=Pip5k1b PE=1 SV=1) HSP 1 Score: 343.969 bits (881), Expect = 1.126e-105 Identity = 165/266 (62.03%), Postives = 205/266 (77.07%), Query Frame = 3
Query: 180 TYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKE 974
TYKK +S I+ A+QLGI TV +K +RD+L++DF VVE++ P G TP+H DF FKT+AP+AFRYFR+ F + DYL SIC + L ELSN GASGS+F++T DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKFYGLYC Q+ G NIR V+MNN++P ++R+H YDLKGSTYKR A+ E+ KP+PT KDLDF ++ E LY + +TY ALM T+QRDCRVLESF IMDYSLLLGIH LD +L+ ++E
Sbjct: 20 TYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFLTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHILDHSLKDKEE 285 HSP 2 Score: 101.679 bits (252), Expect = 6.516e-21 Identity = 60/167 (35.93%), Postives = 92/167 (55.09%), Query Frame = 3
Query: 1827 FSTVLESIQAPVEQ----VELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSV------RKENLIPSDKERQNQSREVIDESE 2297
+ST +ESIQ P + + NP GGIPA++ G++L+LFMGIIDILQSYR+MKK+EH+ KA+ D +SV P+FYA RF F + VFKKI A++ +P +KR +S+ +E + +E +++ R+++ E +
Sbjct: 304 YSTAMESIQGPGKSADGIIAENPDT-----MGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKI---------------------QALKASPSKKRCNSIAALKATSQEIVSSISQEWKDEKRDLLTEGQ 444
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. TrEMBL
Match: A0A5K3ESS6 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 427.943 bits (1099), Expect = 2.839e-135 Identity = 197/293 (67.24%), Postives = 239/293 (81.57%), Query Frame = 3
Query: 129 KEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHAL 1004
K KIGHRR+ D+GTVTYKK TSEIQ+A+QLGI ++ K RD+L +DF VVET+ FPR+G K TP+H LSDF F+TFAP+AFR FRD FQ+DI DYL+S+C QELRELSN GASGSIFYI+ DDEFIIKTVQHKEA+FLQKLLPEYY+NL+QH RTLLPKFYGL+CYQ GKNIRFV+MNNL+P S+++HE+YDLKGS+YKR AN+ E K SPTLKDLDF++ H + ++LE DTY+ALM TI+RDCRVLESF IMDYSLLLG+HN DQ R R ++ ++ +
Sbjct: 38 KTNKKIGHRRVTDQGTVTYKKTPTSEIQRAIQLGIHHSIGTLQQKQVRDVLFRDFEVVETVDFPRSGTKTTPAHGLSDFRFRTFAPVAFRSFRDHFQLDIRDYLNSLCSQELRELSNPGASGSIFYISADDEFIIKTVQHKEANFLQKLLPEYYMNLVQHTRTLLPKFYGLHCYQCSGKNIRFVVMNNLLPSSVKMHERYDLKGSSYKRKANDRELAKASPTLKDLDFKERHPDGIWLEADTYDALMKTIERDCRVLESFRIMDYSLLLGVHNFDQAERDRNRKKERSSDNGV 330 HSP 2 Score: 137.502 bits (345), Expect = 3.984e-30 Identity = 68/131 (51.91%), Postives = 91/131 (69.47%), Query Frame = 3
Query: 1746 GNQIIGKPRES---FNRQKSRSK-STRRIAAFSTVLESIQAPVEQVELNPSDE-EYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPS 2123
G +I R S FNR R+K +R+ AFST +ESI+A VE VE+ P+D + GG+PAR+ GDRL LF+GIIDILQSYR+ KKMEH +K++ +D +SVTNP+FYA+RFQ+ +F+KIPS
Sbjct: 357 GGDVITASRRSVSPFNRSAFRTKLGNKRLTAFSTAMESIEAKVEPVEIEPTDPGKATLLGGLPARSASGDRLFLFIGIIDILQSYRMAKKMEHTLKSVVIDAETVSVTNPSFYARRFQNALGTCIFRKIPS 487
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. TrEMBL
Match: A0A5K3ET03 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 428.328 bits (1100), Expect = 7.335e-135 Identity = 197/293 (67.24%), Postives = 239/293 (81.57%), Query Frame = 3
Query: 129 KEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHAL 1004
K KIGHRR+ D+GTVTYKK TSEIQ+A+QLGI ++ K RD+L +DF VVET+ FPR+G K TP+H LSDF F+TFAP+AFR FRD FQ+DI DYL+S+C QELRELSN GASGSIFYI+ DDEFIIKTVQHKEA+FLQKLLPEYY+NL+QH RTLLPKFYGL+CYQ GKNIRFV+MNNL+P S+++HE+YDLKGS+YKR AN+ E K SPTLKDLDF++ H + ++LE DTY+ALM TI+RDCRVLESF IMDYSLLLG+HN DQ R R ++ ++ +
Sbjct: 38 KTNKKIGHRRVTDQGTVTYKKTPTSEIQRAIQLGIHHSIGTLQQKQVRDVLFRDFEVVETVDFPRSGTKTTPAHGLSDFRFRTFAPVAFRSFRDHFQLDIRDYLNSLCSQELRELSNPGASGSIFYISADDEFIIKTVQHKEANFLQKLLPEYYMNLVQHTRTLLPKFYGLHCYQCSGKNIRFVVMNNLLPSSVKMHERYDLKGSSYKRKANDRELAKASPTLKDLDFKERHPDGIWLEADTYDALMKTIERDCRVLESFRIMDYSLLLGVHNFDQAERDRNRKKERSSDNGV 330 HSP 2 Score: 169.474 bits (428), Expect = 1.288e-40 Identity = 82/161 (50.93%), Postives = 110/161 (68.32%), Query Frame = 3
Query: 1746 GNQIIGKPRES---FNRQKSRSK-STRRIAAFSTVLESIQAPVEQVELNPSDE-EYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKR 2213
G +I R S FNR R+K +R+ AFST +ESI+A VE VE+ P+D + GG+PAR+ GDRL LF+GIIDILQSYR+ KKMEH +K++ +D +SVTNP+FYA+RFQ+ +F+KIPSLD PQ+ G RFR H+AM+Q+ R+R
Sbjct: 357 GGDVITASRRSVSPFNRSAFRTKLGNKRLTAFSTAMESIEAKVEPVEIEPTDPGKATLLGGLPARSASGDRLFLFIGIIDILQSYRMAKKMEHTLKSVVIDAETVSVTNPSFYARRFQNALGTCIFRKIPSLDPPQLFGPKAMRFRRLAHLAMKQSSARRR 517
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. TrEMBL
Match: A0A5K3EUV8 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 427.943 bits (1099), Expect = 8.878e-135 Identity = 197/293 (67.24%), Postives = 239/293 (81.57%), Query Frame = 3
Query: 129 KEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHAL 1004
K KIGHRR+ D+GTVTYKK TSEIQ+A+QLGI ++ K RD+L +DF VVET+ FPR+G K TP+H LSDF F+TFAP+AFR FRD FQ+DI DYL+S+C QELRELSN GASGSIFYI+ DDEFIIKTVQHKEA+FLQKLLPEYY+NL+QH RTLLPKFYGL+CYQ GKNIRFV+MNNL+P S+++HE+YDLKGS+YKR AN+ E K SPTLKDLDF++ H + ++LE DTY+ALM TI+RDCRVLESF IMDYSLLLG+HN DQ R R ++ ++ +
Sbjct: 38 KTNKKIGHRRVTDQGTVTYKKTPTSEIQRAIQLGIHHSIGTLQQKQVRDVLFRDFEVVETVDFPRSGTKTTPAHGLSDFRFRTFAPVAFRSFRDHFQLDIRDYLNSLCSQELRELSNPGASGSIFYISADDEFIIKTVQHKEANFLQKLLPEYYMNLVQHTRTLLPKFYGLHCYQCSGKNIRFVVMNNLLPSSVKMHERYDLKGSSYKRKANDRELAKASPTLKDLDFKERHPDGIWLEADTYDALMKTIERDCRVLESFRIMDYSLLLGVHNFDQAERDRNRKKERSSDNGV 330 HSP 2 Score: 169.474 bits (428), Expect = 1.387e-40 Identity = 82/161 (50.93%), Postives = 110/161 (68.32%), Query Frame = 3
Query: 1746 GNQIIGKPRES---FNRQKSRSK-STRRIAAFSTVLESIQAPVEQVELNPSDE-EYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKR 2213
G +I R S FNR R+K +R+ AFST +ESI+A VE VE+ P+D + GG+PAR+ GDRL LF+GIIDILQSYR+ KKMEH +K++ +D +SVTNP+FYA+RFQ+ +F+KIPSLD PQ+ G RFR H+AM+Q+ R+R
Sbjct: 357 GGDVITASRRSVSPFNRSAFRTKLGNKRLTAFSTAMESIEAKVEPVEIEPTDPGKATLLGGLPARSASGDRLFLFIGIIDILQSYRMAKKMEHTLKSVVIDAETVSVTNPSFYARRFQNALGTCIFRKIPSLDPPQLFGPKAMRFRRLAHLAMKQSSARRR 517
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. TrEMBL
Match: A0A183T4D6 (PIPK domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS11334 PE=4 SV=1) HSP 1 Score: 425.246 bits (1092), Expect = 8.910e-135 Identity = 200/295 (67.80%), Postives = 244/295 (82.71%), Query Frame = 3
Query: 90 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK 971
++ G + E K K K+GHRR+ ++GTVTYKK TSEIQ+A+QLGI+ ++++ K RD+L +DF VVET+ FPR+G K TP+H+LSDF F+TFAP+AFR FRD F++DI DYL+S+C QELRELSN GASGSIFYI+ DDEFI+KTVQHKEA FLQKLLPEYY+NL+QH RTLLPKFYGL+CYQ+ GKNIRFV+MNNL+P SI++HEKYDLKGS+YKR A+E E K SPTLKDLDF++ H E + LE DTY+ALM TI+RDCRVLESF IMDYS LLGIHNLDQ R R+
Sbjct: 23 SRSGRWETESKRAK---KLGHRRVTEQGTVTYKKTPTSEIQRAIQLGIQHSISILQQKPVRDVLFRDFEVVETVDFPRSGSKTTPAHNLSDFRFRTFAPVAFRSFRDTFELDIRDYLNSLCSQELRELSNPGASGSIFYISTDDEFILKTVQHKEADFLQKLLPEYYMNLVQHTRTLLPKFYGLHCYQSGGKNIRFVVMNNLLPSSIKMHEKYDLKGSSYKRKASERELAKSSPTLKDLDFKERHPEGILLEADTYDALMKTIERDCRVLESFRIMDYSFLLGIHNLDQAERDRQ 314 HSP 2 Score: 106.686 bits (265), Expect = 3.581e-20 Identity = 56/124 (45.16%), Postives = 80/124 (64.52%), Query Frame = 3
Query: 1686 NQSNAIDGGSPAAVSPESSIGNQIIGKPRES---FNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAIS 2048
N+++A G + +P S GN P ++ F R R+K +RI A+ST +ESI+A E VE+ P + +I GGIPAR+K GDRL L++GIIDILQSYR++KKMEH +K++ D +S
Sbjct: 350 NRASAF--GEARSTTPSSFTGNLRNTTPPKTASPFLRNPFRAKFQKRITAYSTAMESIEAKAEPVEVEPDERSHILMGGIPARSKSGDRLFLYIGIIDILQSYRVIKKMEHTLKSVVTDGVCLS 471
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. TrEMBL
Match: A0A0X3PYS8 (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha OS=Schistocephalus solidus OX=70667 GN=PI51A PE=4 SV=1) HSP 1 Score: 427.943 bits (1099), Expect = 9.559e-135 Identity = 200/295 (67.80%), Postives = 244/295 (82.71%), Query Frame = 3
Query: 90 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK 971
++ G + E K K K+GHRR+ ++GTVTYKK TSEIQ+A+QLGI+ ++++ K RD+L +DF VVET+ FPR+G K TP+H+LSDF F+TFAP+AFR FRD F++DI DYL+S+C QELRELSN GASGSIFYI+ DDEFI+KTVQHKEA FLQKLLPEYY+NL+QH RTLLPKFYGL+CYQ+ GKNIRFV+MNNL+P SI++HEKYDLKGS+YKR A+E E K SPTLKDLDF++ H E + LE DTY+ALM TI+RDCRVLESF IMDYS LLGIHNLDQ R R+
Sbjct: 27 SRSGRWETESKRAK---KLGHRRVTEQGTVTYKKTPTSEIQRAIQLGIQHSISILQQKPVRDVLFRDFEVVETVDFPRSGSKTTPAHNLSDFRFRTFAPVAFRSFRDTFELDIRDYLNSLCSQELRELSNPGASGSIFYISTDDEFILKTVQHKEADFLQKLLPEYYMNLVQHTRTLLPKFYGLHCYQSGGKNIRFVVMNNLLPSSIKMHEKYDLKGSSYKRKASERELAKSSPTLKDLDFKERHPEGILLEADTYDALMKTIERDCRVLESFRIMDYSFLLGIHNLDQAERDRQ 318 HSP 2 Score: 137.887 bits (346), Expect = 4.825e-30 Identity = 71/149 (47.65%), Postives = 96/149 (64.43%), Query Frame = 3
Query: 1686 NQSNAIDGGSPAAVSPESSIGNQIIGKPRES---FNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPS 2123
N+++A G + +P S GN P ++ F R R+K +RI A+ST +ESI+A E VE+ P + +I GGIPAR+K GDRL L++GIIDILQSYR++KKMEH +K++ D +SVTNP FYA RFQ VF+KI S
Sbjct: 354 NRASAF--GEARSTTPSSFTGNLRNTTPPKTASPFLRNPFRAKFQKRITAYSTAMESIEAKAEPVEVEPDERSHILMGGIPARSKSGDRLFLYIGIIDILQSYRVIKKMEHTLKSVVTDGETVSVTNPAFYAHRFQTALGRFVFRKIQS 500
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Cavefish
Match: pip5k1ca (phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like [Source:NCBI gene;Acc:103021640]) HSP 1 Score: 356.681 bits (914), Expect = 5.323e-110 Identity = 172/291 (59.11%), Postives = 218/291 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSS 1010
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFI+KTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L L++DTY AL+ T+QRDC VLESF IMDYSLLLG+HNLDQ E EQ+ + SS
Sbjct: 67 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTKDDEFIVKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRVVVMNNILPRVVRMHLKYDLKGSTYKRRASKKEREKAKPTFKDLDFMQDIADGLLLDLDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNLDQ-----AEREQQTEGSQGSS 352 HSP 2 Score: 95.9005 bits (237), Expect = 7.325e-20 Identity = 50/102 (49.02%), Postives = 67/102 (65.69%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSL 2126
A +ST LESIQ E +++ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA RF F ++ VF+K SL
Sbjct: 362 ALYSTALESIQGASACAEDIDTEDT---MGGIPAVNSKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYADRFFRFMSSTVFRKSTSL 460
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Cavefish
Match: pip5k1cb (phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like [Source:NCBI gene;Acc:103026952]) HSP 1 Score: 354.369 bits (908), Expect = 8.238e-110 Identity = 172/291 (59.11%), Postives = 217/291 (74.57%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSI-RIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSS 1010
KIGHRR++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGSIFY+T DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR ++MNN++P + R+H K+DLKGSTYKR A++ E+ K PT KDLDF + + L L+ DT+ AL+ T+QRDC VLESF IMDYSLLLG+HNLDQ E+EQ+ S
Sbjct: 40 KIGHRRVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSIFYVTRDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCIQSGGKNIRILVMNNVLPRVFRMHLKFDLKGSTYKRRASKKEREKSRPTFKDLDFLQEVPDGLLLDTDTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNLDQ-------AEREQQTEGCQS 323 HSP 2 Score: 84.7297 bits (208), Expect = 1.940e-16 Identity = 46/97 (47.42%), Postives = 61/97 (62.89%), Query Frame = 3
Query: 1821 AAFSTVLESI-QAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVF 2108
A +ST +ESI V ++ D GGIPA + G+RL+LF+GIIDILQSYR++KK+EH KA+ D +SV P FYA RF F ++ VF
Sbjct: 334 ALYSTAMESILGGAVCGDSIDTEDT----MGGIPAVSGKGERLLLFVGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPNFYADRFFKFMSSTVF 426
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Cavefish
Match: pip5k1ca (phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like [Source:NCBI gene;Acc:103021640]) HSP 1 Score: 357.066 bits (915), Expect = 1.140e-109 Identity = 172/291 (59.11%), Postives = 218/291 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSS 1010
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFI+KTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L L++DTY AL+ T+QRDC VLESF IMDYSLLLG+HNLDQ E EQ+ + SS
Sbjct: 67 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTKDDEFIVKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRVVVMNNILPRVVRMHLKYDLKGSTYKRRASKKEREKAKPTFKDLDFMQDIADGLLLDLDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNLDQ-----AEREQQTEGSQGSS 352 HSP 2 Score: 96.2857 bits (238), Expect = 6.897e-20 Identity = 50/102 (49.02%), Postives = 67/102 (65.69%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSL 2126
A +ST LESIQ E +++ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA RF F ++ VF+K SL
Sbjct: 362 ALYSTALESIQGASACAEDIDTEDT---MGGIPAVNSKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYADRFFRFMSSTVFRKSTSL 460
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Cavefish
Match: pip5k1ca (phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like [Source:NCBI gene;Acc:103021640]) HSP 1 Score: 356.681 bits (914), Expect = 1.873e-109 Identity = 172/291 (59.11%), Postives = 218/291 (74.91%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSS 1010
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFI+KTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L L++DTY AL+ T+QRDC VLESF IMDYSLLLG+HNLDQ E EQ+ + SS
Sbjct: 67 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTKDDEFIVKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRVVVMNNILPRVVRMHLKYDLKGSTYKRRASKKEREKAKPTFKDLDFMQDIADGLLLDLDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNLDQ-----AEREQQTEGSQGSS 352 HSP 2 Score: 96.2857 bits (238), Expect = 7.244e-20 Identity = 55/134 (41.04%), Postives = 77/134 (57.46%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSS 2222
A +ST LESIQ E +++ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P+FYA RF F ++ VF+K SL S +R R + + P ++S
Sbjct: 362 ALYSTALESIQGASACAEDIDTEDT---MGGIPAVNSKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPSFYADRFFRFMSSTVFRKSTSLKS-----SPSKRGRGSLAVPKHSGPGAAWSAS 487
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Cavefish
Match: pip5k1cb (phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like [Source:NCBI gene;Acc:103026952]) HSP 1 Score: 356.681 bits (914), Expect = 3.644e-109 Identity = 169/275 (61.45%), Postives = 212/275 (77.09%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSI-RIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLR 962
KIGHRR++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGSIFY+T DDEFIIKTVQHKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR ++MNN++P + R+H K+DLKGSTYKR A++ E+ K PT KDLDF + + L L+ DT+ AL+ T+QRDC VLESF IMDYSLLLG+HNLDQ R
Sbjct: 55 KIGHRRVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSIFYVTRDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCIQSGGKNIRILVMNNVLPRVFRMHLKFDLKGSTYKRRASKKEREKSRPTFKDLDFLQEVPDGLLLDTDTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNLDQAER 329 HSP 2 Score: 84.3445 bits (207), Expect = 3.111e-16 Identity = 47/103 (45.63%), Postives = 63/103 (61.17%), Query Frame = 3
Query: 1803 KSTRRIAAFSTVLESI-QAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVF 2108
K + A +ST +ESI V ++ D GGIPA + G+RL+LF+GIIDILQSYR++KK+EH KA+ D +SV P FYA RF F ++ VF
Sbjct: 343 KPAAQRALYSTAMESILGGAVCGDSIDTEDT----MGGIPAVSGKGERLLLFVGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPNFYADRFFKFMSSTVF 441
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Sea Lamprey
Match: pip5k1ab (phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b [Source:ZFIN;Acc:ZDB-GENE-041111-123]) HSP 1 Score: 326.635 bits (836), Expect = 2.762e-103 Identity = 156/261 (59.77%), Postives = 202/261 (77.39%), Query Frame = 3
Query: 189 KKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMR 968
+ T+S ++ A++LGI TV +K +RD+L++DF VVE++ FP G TP+H SDF FKT+AP+AFRYFR+ F + DYL S+C + L EL+N GASGS+F++T DDEFIIKTV HKEA FLQKLLP YY+NL Q+ RTLLPKFYGLYC Q+ GKNIR V+MNNL+P ++++H K+DLKGSTYKR A+ E+ K +PT KDLDF ++H + L L+ DTY A+ T+QRDC VLESF IMDYSLL+G+HNLDQ+ R R
Sbjct: 1 QTTSSALRGAIELGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYSDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELTNPGASGSVFFVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNVRTLLPKFYGLYCVQSGGKNIRLVVMNNLLPRAMKMHIKFDLKGSTYKRRASRKEREKSNPTFKDLDFIQDHPDGLLLDSDTYNAMSKTLQRDCLVLESFKIMDYSLLIGVHNLDQSQRER 261 HSP 2 Score: 49.6766 bits (117), Expect = 2.138e-6 Identity = 21/44 (47.73%), Postives = 30/44 (68.18%), Query Frame = 3
Query: 1989 IMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIP 2120
++KK+EH+ KA+ D +SV P+FYA+RF F N VF+K P
Sbjct: 312 LIKKLEHSWKALVHDGDTVSVHRPSFYAERFLKFMCNQVFRKTP 355
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Sea Lamprey
Match: pip5k1ab (phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b [Source:ZFIN;Acc:ZDB-GENE-041111-123]) HSP 1 Score: 326.635 bits (836), Expect = 7.370e-103 Identity = 156/261 (59.77%), Postives = 202/261 (77.39%), Query Frame = 3
Query: 189 KKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMR 968
+ T+S ++ A++LGI TV +K +RD+L++DF VVE++ FP G TP+H SDF FKT+AP+AFRYFR+ F + DYL S+C + L EL+N GASGS+F++T DDEFIIKTV HKEA FLQKLLP YY+NL Q+ RTLLPKFYGLYC Q+ GKNIR V+MNNL+P ++++H K+DLKGSTYKR A+ E+ K +PT KDLDF ++H + L L+ DTY A+ T+QRDC VLESF IMDYSLL+G+HNLDQ+ R R
Sbjct: 1 QTTSSALRGAIELGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYSDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELTNPGASGSVFFVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNVRTLLPKFYGLYCVQSGGKNIRLVVMNNLLPRAMKMHIKFDLKGSTYKRRASRKEREKSNPTFKDLDFIQDHPDGLLLDSDTYNAMSKTLQRDCLVLESFKIMDYSLLIGVHNLDQSQRER 261 HSP 2 Score: 102.449 bits (254), Expect = 2.059e-23 Identity = 49/100 (49.00%), Postives = 68/100 (68.00%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIP 2120
A +ST +ESIQA E+ + GG+PA+N G+RL+L++GIIDILQSYR++KK+EH+ KA+ D +SV P+FYA+RF F N VF+K P
Sbjct: 286 ALYSTAMESIQAESRTGATTHQTEDCM--GGVPAKNSKGERLVLYLGIIDILQSYRLIKKLEHSWKALVHDGDTVSVHRPSFYAERFLKFMCNQVFRKTP 383
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Sea Lamprey
Match: pip5k1ab (phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b [Source:ZFIN;Acc:ZDB-GENE-041111-123]) HSP 1 Score: 319.701 bits (818), Expect = 1.232e-100 Identity = 153/251 (60.96%), Postives = 195/251 (77.69%), Query Frame = 3
Query: 219 LQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMR 968
++LGI TV +K +RD+L++DF VVE++ FP G TP+H SDF FKT+AP+AFRYFR+ F + DYL S+C + L EL+N GASGS+F++T DDEFIIKTV HKEA FLQKLLP YY+NL Q+ RTLLPKFYGLYC Q+ GKNIR V+MNNL+P ++++H K+DLKGSTYKR A+ E+ K +PT KDLDF ++H + L L+ DTY A+ T+QRDC VLESF IMDYSLL+G+HNLDQ+ R R
Sbjct: 1 IELGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYSDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELTNPGASGSVFFVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNVRTLLPKFYGLYCVQSGGKNIRLVVMNNLLPRAMKMHIKFDLKGSTYKRRASRKEREKSNPTFKDLDFIQDHPDGLLLDSDTYNAMSKTLQRDCLVLESFKIMDYSLLIGVHNLDQSQRER 251 HSP 2 Score: 93.9745 bits (232), Expect = 1.037e-20 Identity = 40/71 (56.34%), Postives = 55/71 (77.46%), Query Frame = 3
Query: 1908 GGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIP 2120
GG+PA+N G+RL+L++GIIDILQSYR++KK+EH+ KA+ D +SV P+FYA+RF F N VF+K P
Sbjct: 288 GGVPAKNSKGERLVLYLGIIDILQSYRLIKKLEHSWKALVHDGDTVSVHRPSFYAERFLKFMCNQVFRKTP 358
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003871.1 (pep scaffold:Pmarinus_7.0:GL484476:49:10994:1 gene:ENSPMAG00000003543.1 transcript:ENSPMAT00000003871.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 66.6254 bits (161), Expect = 8.301e-12 Identity = 58/182 (31.87%), Postives = 83/182 (45.60%), Query Frame = 3
Query: 432 DYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYY---INLIQHPR-TLLPKFYGLY------CYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPT-LKDLD---FRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLG 935
D++ S+ H + + G SGS FY T D+ FI+K + E + P Y+ N + R T L K G+Y K ++M NL ++ + +DLKGS R+ + E +K P L LD R D+ LY+ AL I RD L S I+DYSLL+G
Sbjct: 106 DFIHSLSHC-MPWQARGGKSGSAFYETQDERFILKQMSRLEVQSFLEFAPHYFHYITNAVTQKRPTALAKILGVYRIGFKNSQTNTEKKQDLLVMENLFYGRKMTQVFDLKGSLRNRNV-KAELSKEGPCELVLLDENLLRVVRDDPLYVRPHCKAALTAAILRDAHFLSSHLIIDYSLLVG 285
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Sea Lamprey
Match: pip5kl1 (phosphatidylinositol-4-phosphate 5-kinase-like 1 [Source:ZFIN;Acc:ZDB-GENE-060526-248]) HSP 1 Score: 60.8474 bits (146), Expect = 2.746e-10 Identity = 50/157 (31.85%), Postives = 78/157 (49.68%), Query Frame = 3
Query: 360 DFTFKTFAPIAFRYFRDFFQVDITDYLDSI----CHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIR-FVIMNNLV-PSIRIHEKYDLKGSTYKRSANETEKTKPS-PTLKDLDF 809
DF +TFA F FR + DY+ S+ C+ L+ +SN+ S + F++T D F +KT +E FL + L EY + ++P TLL K GL+ + + F++M ++ P RI +YD+KG R + P LKD +F
Sbjct: 96 DFVLETFAGPVFASFRQLLGLREDDYVGSLASPGCY--LQFISNS-KSKADFFLTNDKRFFLKTQNRREYRFLLRHLREYVQHFEKYPHTLLVKILGLHRISLSNEPKKYFIVMQSVFYPDERIAVRYDIKGCELGRWTQPAPEGSPVIVVLKDNNF 249
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Yeast
Match: MSS4 (Phosphatidylinositol-4-phosphate 5-kinase; involved in actin cytoskeleton organization and cell morphogenesis; multicopy suppressor of stt4 mutation [Source:SGD;Acc:S000002616]) HSP 1 Score: 129.028 bits (323), Expect = 5.789e-31 Identity = 89/257 (34.63%), Postives = 141/257 (54.86%), Query Frame = 3
Query: 228 GIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQE-LRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLY------CYQTMGKN--IRFVIMNNLVPS-IRIHEKYDLKGSTYKRSAN-ETEKTKPS----PTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQ 953
GI++ V+ K + DF + L F G + TPS + F FK + P FR R F +D DYL S+ + L EL++ G SGS FY + D ++IIKT+ H E L+K + EYY ++ +P TL+ +FYGL+ +Q K+ I F++MNNL P + IH YDLKGST+ R N + E+ P +KDL++ + + + + + + +++D +L + MDYSLL+GIH++++
Sbjct: 395 GIRVAVSRCSGIMK-PLTPADFRFTKKLAFDYHGNELTPSSQYA-FKFKDYCPEVFRELRALFGLDPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRKHIQEYYNHVRDNPNTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDLKGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKK-KTFLTQLKKDVELLAKLNTMDYSLLIGIHDINK 648
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Yeast
Match: FAB1 (1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis [Source:SGD;Acc:S000001915]) HSP 1 Score: 66.2402 bits (160), Expect = 2.599e-11 Identity = 54/173 (31.21%), Postives = 75/173 (43.35%), Query Frame = 3
Query: 474 SNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHP----RTLLPKFYGLYCYQT-------MGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLY---LEVDTYEA--LMNTIQRDCRVLESFSIMDYSLLLGIHN 944
SN G SGS F T DD FIIK + H E K P Y+ + Q T L K +G Y Q + +IM NL + +DLKGS R +T K ++ +N E +Y + V Y+ L ++ D L ++MDYSL++GI N
Sbjct: 2039 SNGGKSGSGFLKTLDDRFIIKELSHAELEAFIKFAPSYFEYMAQAMFHDLPTTLAKVFGFYQIQVKSSISSSKSYKMDVIIMENLFYEKKTTRIFDLKGSMRNRHVEQTGKA------NEVLLDENMVEYIYESPIHVREYDKKLLRASVWNDTLFLAKMNVMDYSLVIGIDN 2205
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Nematostella
Match: EDO41004 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5N2]) HSP 1 Score: 362.073 bits (928), Expect = 1.259e-115 Identity = 168/286 (58.74%), Postives = 220/286 (76.92%), Query Frame = 3
Query: 120 KVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKE 974
KV KSK+GHRR++++G TYKK +S + A+QLGI TV K +RD+L++DF +ET+ FP G ++TPSH SDF FK++AP+AFR+FR+ F + D++ ++C++ L ELSN GASGS+FY+TCDDEFIIKTVQHKEA FLQKLLP YY+NL Q+ RTLLPKF+GL+CYQ GKNIR V+MNNL+P + H KYDLKGSTYKR A++ E+ K PTLKDLDF + E ++LE + Y +L+ T+QRDCRVLESF IMDYS+LLGIHN+D+ R R++
Sbjct: 2 KVTTPKSKLGHRRVDEKGETTYKKTPSSALMSAIQLGIGFTVGRLSAKPERDVLMQDFAQIETVVFPSEGTRETPSHKFSDFKFKSYAPVAFRFFRELFSMRPDDFMMALCNEPLVELSNPGASGSLFYVTCDDEFIIKTVQHKEAEFLQKLLPGYYLNLNQNKRTLLPKFFGLFCYQCGGKNIRLVVMNNLLPRDWKFHFKYDLKGSTYKRRASKAERAKKHPTLKDLDFIVDFPEGIFLEPEIYTSLIKTLQRDCRVLESFKIMDYSILLGIHNIDEAARERQQ 287 HSP 2 Score: 90.1225 bits (222), Expect = 5.731e-19 Identity = 40/72 (55.56%), Postives = 53/72 (73.61%), Query Frame = 3
Query: 1908 GGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPS 2123
G IPARN G++L+LF+GIIDILQSYR+ KK+EH KA+ D +SV P+FY +RF +F + VFKK+P
Sbjct: 328 GSIPARNAKGEKLLLFVGIIDILQSYRLKKKLEHGWKALVHDGDTVSVHRPSFYCKRFLEFMTSNVFKKLPG 399
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Nematostella
Match: EDO28919 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T544]) HSP 1 Score: 281.567 bits (719), Expect = 2.551e-87 Identity = 143/283 (50.53%), Postives = 194/283 (68.55%), Query Frame = 3
Query: 120 KVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDF-FQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMN-NLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLR 962
KV KSK+GHRR++++G TYKK +S + A+QLGI TV K +RD+L++DF +ET+ FP G ++TPSH SDF FK++AP+AFR+F D F D ++C++ L ELSN GASGS+FY+TCDDEFIIKTVQHKEA FLQKLLP YY+ L+Q P+FY + G ++ ++ L ++ +H +GSTYKR A++ E+ K PTLKDLDF + E ++LE + Y +L+ T+QRDCRVLESF IMDYS+LLGIHN+D+ R
Sbjct: 2 KVTTPKSKLGHRRVDEKGETTYKKTPSSALMSAIQLGIGFTVGRLSAKPERDVLMQDFAQIETVVFPSEGTRETPSHKFSDFKFKSYAPVAFRWFYDIRFMPDNM----ALCNEPLVELSNPGASGSLFYVTCDDEFIIKTVQHKEAEFLQKLLPGYYLVLLQRD----PRFYDI-----NGNPLKILVYQVTLCKTVNLHLHKICRGSTYKRRASKAERAKKHPTLKDLDFIVDFPEGIFLEPEIYTSLIKTLQRDCRVLESFKIMDYSILLGIHNIDEAAR 271
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Nematostella
Match: EDO35742 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKP4]) HSP 1 Score: 120.168 bits (300), Expect = 7.407e-29 Identity = 72/208 (34.62%), Postives = 119/208 (57.21%), Query Frame = 3
Query: 333 KDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLI-QHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLD 950
++ PSH F FK + P+ FR R+ F ++ D ++ + S G SG+ F+++ + F +K ++ +E L +L Y+ +++ QH TLLP++ +Y GK ++M ++ + ++IH+KYDLKGST R A+ EKT+ +PT KD DF K+ + L + + L+ I+ D L S +IMDYSLL+GIH+ D
Sbjct: 75 ENLPSH----FKFKEYCPMVFRNLRERFGIEDKDLAEAFQVPPISSDS-PGRSGAKFFLSQNKRFYVKVIESEEVERLHNILQPYHHHIVEQHANTLLPQYLAMYRVTVDGKESYMLVMTSVFSTRLKIHKKYDLKGSTVDRQASLKEKTRDNPTFKDNDFTKD-NVKLVIGDEAKAVLVERIKADVEFLISLNIMDYSLLVGIHDCD 276
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Medaka
Match: pip5k1ca (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma [Source:NCBI gene;Acc:101162441]) HSP 1 Score: 357.451 bits (916), Expect = 9.138e-110 Identity = 169/278 (60.79%), Postives = 213/278 (76.62%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK 971
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L L+ DTY AL+ T+QRDC VLESF IMDYSLLLG+HN+DQ R R+
Sbjct: 61 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRVVVMNNVLPRVVRMHLKYDLKGSTYKRRASKKEREKARPTFKDLDFMQDTPDGLMLDQDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNMDQADRERQ 338 HSP 2 Score: 90.1225 bits (222), Expect = 5.321e-18 Identity = 46/97 (47.42%), Postives = 62/97 (63.92%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFK 2111
A +ST +ESIQ +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P FYA RF F ++ VF+
Sbjct: 357 ALYSTAMESIQGGAACGGSIDTDDT---MGGIPAVNGKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPGFYADRFFKFMSSTVFR 450
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Medaka
Match: pip5k1ca (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma [Source:NCBI gene;Acc:101162441]) HSP 1 Score: 354.369 bits (908), Expect = 1.377e-109 Identity = 169/278 (60.79%), Postives = 213/278 (76.62%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK 971
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L L+ DTY AL+ T+QRDC VLESF IMDYSLLLG+HN+DQ R R+
Sbjct: 13 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRVVVMNNVLPRVVRMHLKYDLKGSTYKRRASKKEREKARPTFKDLDFMQDTPDGLMLDQDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNMDQADRERQ 290 HSP 2 Score: 89.7373 bits (221), Expect = 5.758e-18 Identity = 46/97 (47.42%), Postives = 62/97 (63.92%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFK 2111
A +ST +ESIQ +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P FYA RF F ++ VF+
Sbjct: 309 ALYSTAMESIQGGAACGGSIDTDDT---MGGIPAVNGKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPGFYADRFFKFMSSTVFR 402
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Medaka
Match: pip5k1ca (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma [Source:NCBI gene;Acc:101162441]) HSP 1 Score: 357.066 bits (915), Expect = 2.254e-109 Identity = 169/278 (60.79%), Postives = 213/278 (76.62%), Query Frame = 3
Query: 141 KIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPS-IRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRK 971
KIGHR ++ G TYKK T+S ++ A+QLGI TV +K +RD+L++DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DYL S+C++ L ELSN GASGS+FY+T DDEFIIKTV HKEA FLQKLLP YY+NL Q+PRTLLPKF+GLYC Q+ GKNIR V+MNN++P +R+H KYDLKGSTYKR A++ E+ K PT KDLDF ++ + L L+ DTY AL+ T+QRDC VLESF IMDYSLLLG+HN+DQ R R+
Sbjct: 61 KIGHRGVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQSGGKNIRVVVMNNVLPRVVRMHLKYDLKGSTYKRRASKKEREKARPTFKDLDFMQDTPDGLMLDQDTYNALVKTLQRDCLVLESFKIMDYSLLLGVHNMDQADRERQ 338 HSP 2 Score: 90.1225 bits (222), Expect = 5.221e-18 Identity = 46/97 (47.42%), Postives = 62/97 (63.92%), Query Frame = 3
Query: 1821 AAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFK 2111
A +ST +ESIQ +D+ GGIPA N G+RL+L++GIIDILQSYR++KK+EH KA+ D +SV P FYA RF F ++ VF+
Sbjct: 357 ALYSTAMESIQGGAACGGSIDTDDT---MGGIPAVNGKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHRPGFYADRFFKFMSSTVFR 450
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Medaka
Match: ENSORLT00000046121.1 (phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [Source:NCBI gene;Acc:105355004]) HSP 1 Score: 346.28 bits (887), Expect = 1.478e-108 Identity = 167/283 (59.01%), Postives = 207/283 (73.14%), Query Frame = 3
Query: 135 KSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENE 980
K IGHR I+ +G TYKK ++S ++ A+QLGI TV K +RD+LL+DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DY+ S+C+ L ELSN+GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP Y++NL Q+ RTLLPKFYGLYC Q GKNIR V+MNNL+P ++R+H KYDLKGSTYKR A+ E+ K PT KDLDF ++ E L LE D Y AL TI RDC +L+SF IMDYS LL IHN+DQ R + E
Sbjct: 31 KKTIGHRGIDPQGETTYKKTSSSTLKGAIQLGIAHTVGSLTQKPERDVLLQDFEVVESIFFPSEGSNLTPAHHYGDFKFKTYAPVAFRYFRELFGIRPDDYMYSLCNDGLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYFMNLNQNRRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPNTVRMHSKYDLKGSTYKRRASAKEREKAIPTFKDLDFMQDMQEGLLLEGDKYIALCKTIHRDCLLLQSFKIMDYSFLLAIHNMDQACRDQASEE 313 HSP 2 Score: 68.1662 bits (165), Expect = 1.978e-11 Identity = 34/69 (49.28%), Postives = 47/69 (68.12%), Query Frame = 3
Query: 1827 FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLD 2033
+ST +ESIQA + + TGGIPA N G+RL++++GIIDILQSYR +KK+EH+ KA+ D
Sbjct: 331 YSTAIESIQA----------EGGAMATGGIPAWNSRGERLLVYIGIIDILQSYRFVKKLEHSWKALVHD 389
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Medaka
Match: ENSORLT00000028012.1 (phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [Source:NCBI gene;Acc:105355004]) HSP 1 Score: 348.591 bits (893), Expect = 5.642e-108 Identity = 167/283 (59.01%), Postives = 207/283 (73.14%), Query Frame = 3
Query: 135 KSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVP-SIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENE 980
K IGHR I+ +G TYKK ++S ++ A+QLGI TV K +RD+LL+DF VVE++ FP G TP+H DF FKT+AP+AFRYFR+ F + DY+ S+C+ L ELSN+GASGS+FY++ DDEFIIKTVQHKEA FLQKLLP Y++NL Q+ RTLLPKFYGLYC Q GKNIR V+MNNL+P ++R+H KYDLKGSTYKR A+ E+ K PT KDLDF ++ E L LE D Y AL TI RDC +L+SF IMDYS LL IHN+DQ R + E
Sbjct: 40 KKTIGHRGIDPQGETTYKKTSSSTLKGAIQLGIAHTVGSLTQKPERDVLLQDFEVVESIFFPSEGSNLTPAHHYGDFKFKTYAPVAFRYFRELFGIRPDDYMYSLCNDGLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYFMNLNQNRRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPNTVRMHSKYDLKGSTYKRRASAKEREKAIPTFKDLDFMQDMQEGLLLEGDKYIALCKTIHRDCLLLQSFKIMDYSFLLAIHNMDQACRDQASEE 322 HSP 2 Score: 102.449 bits (254), Expect = 5.179e-22 Identity = 59/133 (44.36%), Postives = 78/133 (58.65%), Query Frame = 3
Query: 1827 FSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSV 2225
+ST +ESIQA + S +E TGGIPA N G+RL++++GIIDILQSYR +KK+EH+ KA+ D +SV P FYA+RF+ F VFKK+P P S RR V A+ P SS+
Sbjct: 340 YSTAIESIQAEGGAMASTGSADE---TGGIPAWNSRGERLLVYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPRFYAERFEKFMCLRVFKKMPLKSSP----SKKRRANGPVKKAVGFGPSLSAQSSI 465
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Planmine SMEST
Match: SMESG000017265.1 (SMESG000017265.1) HSP 1 Score: 1529.61 bits (3959), Expect = 0.000e+0 Identity = 769/769 (100.00%), Postives = 769/769 (100.00%), Query Frame = 3
Query: 90 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADIDNKEVKFVDGENEPLVFNKSAIGGLSKLVKKYKKISPEASSRKDEFIKKLYPIGKQLHSYISVNPKCIIKSVENCVERVFQSVWLDCDKDLYSVVPPXXXXXXXXXXXXXXXXXXXXXXXXDTDVIYNSLIKNSDPDNDENTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSPTDAANANKFALENSPTL 2396
AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADIDNKEVKFVDGENEPLVFNKSAIGGLSKLVKKYKKISPEASSRKDEFIKKLYPIGKQLHSYISVNPKCIIKSVENCVERVFQSVWLDCDKDLYSVVPPVAILSSGSSDASSVIGSEEEISSIDTDVIYNSLIKNSDPDNDENTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSPTDAANANKFALENSPTL
Sbjct: 5 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADIDNKEVKFVDGENEPLVFNKSAIGGLSKLVKKYKKISPEASSRKDEFIKKLYPIGKQLHSYISVNPKCIIKSVENCVERVFQSVWLDCDKDLYSVVPPVAILSSGSSDASSVIGSEEEISSIDTDVIYNSLIKNSDPDNDENTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSPTDAANANKFALENSPTL 773
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Planmine SMEST
Match: SMESG000017265.1 (SMESG000017265.1) HSP 1 Score: 1472.22 bits (3810), Expect = 0.000e+0 Identity = 748/769 (97.27%), Postives = 748/769 (97.27%), Query Frame = 3
Query: 90 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADIDNKEVKFVDGENEPLVFNKSAIGGLSKLVKKYKKISPEASSRKDEFIKKLYPIGKQLHSYISVNPKCIIKSVENCVERVFQSVWLDCDKDLYSVVPPXXXXXXXXXXXXXXXXXXXXXXXXDTDVIYNSLIKNSDPDNDENTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSPTDAANANKFALENSPTL 2396
AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADIDNKEVKFVDGENEPLVFNKSAIGGLSKLVKKYKKISPEASSRKDEFIKKLYPIGKQLHSYISVNPKCIIKSVENCVERVFQSVWLDCDKDLYSVVPPVAILSSGSSDASSVIGSEEEISSIDTDVIYNSLIKNSDPDNDENTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPS MRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSPTDAANANKFALENSPTL
Sbjct: 5 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADIDNKEVKFVDGENEPLVFNKSAIGGLSKLVKKYKKISPEASSRKDEFIKKLYPIGKQLHSYISVNPKCIIKSVENCVERVFQSVWLDCDKDLYSVVPPVAILSSGSSDASSVIGSEEEISSIDTDVIYNSLIKNSDPDNDENTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPS--------------------PMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSPTDAANANKFALENSPTL 753
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Planmine SMEST
Match: SMESG000017265.1 (SMESG000017265.1) HSP 1 Score: 1417.14 bits (3667), Expect = 0.000e+0 Identity = 714/714 (100.00%), Postives = 714/714 (100.00%), Query Frame = 3
Query: 90 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADIDNKEVKFVDGENEPLVFNKSAIGGLSKLVKKYKKISPEASSRKDEFIKKLYPIGKQLHSYISVNPKCIIKSVENCVERVFQSVWLDCDKDLYSVVPPXXXXXXXXXXXXXXXXXXXXXXXXDTDVIYNSLIKNSDPDNDENTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRK 2231
AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADIDNKEVKFVDGENEPLVFNKSAIGGLSKLVKKYKKISPEASSRKDEFIKKLYPIGKQLHSYISVNPKCIIKSVENCVERVFQSVWLDCDKDLYSVVPPVAILSSGSSDASSVIGSEEEISSIDTDVIYNSLIKNSDPDNDENTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRK
Sbjct: 5 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADIDNKEVKFVDGENEPLVFNKSAIGGLSKLVKKYKKISPEASSRKDEFIKKLYPIGKQLHSYISVNPKCIIKSVENCVERVFQSVWLDCDKDLYSVVPPVAILSSGSSDASSVIGSEEEISSIDTDVIYNSLIKNSDPDNDENTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRK 718
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Planmine SMEST
Match: SMESG000017265.1 (SMESG000017265.1) HSP 1 Score: 802.742 bits (2072), Expect = 0.000e+0 Identity = 391/411 (95.13%), Postives = 396/411 (96.35%), Query Frame = 3
Query: 90 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADI---DNKEVKFVDGENEPLVFNKSAIG 1313
AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIAD N + +DG + V +S+IG
Sbjct: 5 AKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQNLRMRKENEQEQKNHALSSPNHAVKDMSVFEDENSKTKNDSPDISQLIIQKDSFLSDENNRNSIKDIESELLLNIKSSENSESTSGDYYCTPGIADTIRGQNNQSNAIDGGSPAAVSPESSIG 415 HSP 2 Score: 501.901 bits (1291), Expect = 1.070e-165 Identity = 243/244 (99.59%), Postives = 244/244 (100.00%), Query Frame = 3
Query: 1665 NTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSPTDAANANKFALENSPTL 2396
+TIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSPTDAANANKFALENSPTL
Sbjct: 388 DTIRGQNNQSNAIDGGSPAAVSPESSIGNQIIGKPRESFNRQKSRSKSTRRIAAFSTVLESIQAPVEQVELNPSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKKIPSLDQPQILGSHVRRFRNFVHMAMRQNPDRKRTSSVRKENLIPSDKERQNQSREVIDESELVKDEFENLGMPEYSPTDAANANKFALENSPTL 631
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Planmine SMEST
Match: SMESG000010509.1 (SMESG000010509.1) HSP 1 Score: 444.121 bits (1141), Expect = 5.044e-145 Identity = 206/274 (75.18%), Postives = 242/274 (88.32%), Query Frame = 3
Query: 132 EKSKIGHRRINDEGTVTYKKKTTSEIQKALQLGIKITVTLAHNKSKRDMLLKDFGVVETLPFPRTGGKDTPSHDLSDFTFKTFAPIAFRYFRDFFQVDITDYLDSICHQELRELSNAGASGSIFYITCDDEFIIKTVQHKEASFLQKLLPEYYINLIQHPRTLLPKFYGLYCYQTMGKNIRFVIMNNLVPSIRIHEKYDLKGSTYKRSANETEKTKPSPTLKDLDFRKNHDESLYLEVDTYEALMNTIQRDCRVLESFSIMDYSLLLGIHNLDQ 953
+K KIGHRR+N EGTVT+KKKTTSEIQKA+QLG+ I+V +NK KRDMLLKDFGVVE + P+TG + TP+H LSDF F+T+APIAFR+FRD F+VD+ +++DSIC ++LRELSN GASGSIFYIT DDEFIIKTV KEA FLQKLLPEYYINL+QHPRTLLPKFYGLYCY+TMGKNIRFVIMNNL+PSI+IHEKYDLKGSTYKR A++ E++K SPTLKDLDF++NH L LE +TY+ALM+TI RDC VLESFSIMD+SLLLGIHN+DQ
Sbjct: 20 KKQKIGHRRVNAEGTVTFKKKTTSEIQKAIQLGVNISVGSINNKPKRDMLLKDFGVVELISIPKTGTRTTPAHQLSDFQFRTYAPIAFRFFRDMFKVDMCEFMDSICTKDLRELSNPGASGSIFYITLDDEFIIKTVDKKEAIFLQKLLPEYYINLMQHPRTLLPKFYGLYCYETMGKNIRFVIMNNLLPSIKIHEKYDLKGSTYKRYASKKERSKSSPTLKDLDFKENHPNGLILEPETYDALMSTISRDCMVLESFSIMDFSLLLGIHNVDQ 293 HSP 2 Score: 123.25 bits (308), Expect = 4.948e-29 Identity = 61/111 (54.95%), Postives = 77/111 (69.37%), Query Frame = 3
Query: 1785 RQKSRSKSTRRIAAFSTVLESIQAPVEQVELN-PSDEEYIPTGGIPARNKGGDRLILFMGIIDILQSYRIMKKMEHNVKAIFLDPSAISVTNPTFYAQRFQDFFANIVFKK 2114
R S +S +RIAA+ T LESIQ +D +P+GGIPARN G+RL L++GIIDILQSY+I KK+EH K++ D AISVTNPTFY QRFQDFF+ VF++
Sbjct: 365 RSSSHGRSVKRIAAYCTPLESIQRDSHTALTEYGNDTNDLPSGGIPARNSKGERLCLYLGIIDILQSYQINKKLEHGFKSLVQDGKAISVTNPTFYKQRFQDFFSKFVFRR 475 The following BLAST results are available for this feature:
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Phosphatidylinositol 4 phosphate 5 kinase type 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30005638 ID=SMED30005638|Name=Phosphatidylinositol 4 phosphate 5 kinase type 1|organism=Schmidtea mediterranea sexual|type=transcript|length=3118bpback to top protein sequence of SMED30005638-orf-1 >SMED30005638-orf-1 ID=SMED30005638-orf-1|Name=SMED30005638-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=774bp MSINAKEGMYYEERKVLKEKSKIGHRRINDEGTVTYKKKTTSEIQKALQLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
