Cytochrome P450 2K1-like protein

Query:   98 GYRKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLE---KLPKFVRFLFWC-SEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            G  +LP G      IGN+++L  + +   L N SK++GP+F +  G + +VVL     + +   + G   S R    + E  N  + ILF +   W   R   L  L+NF   ++ + + V EE   L+++++       +   +   +  N++  +I + RF+ + + +  L E   EN +I        L  PW++     P  + +L    ++   N+    S+  E I+EH+   D MN   + ID FL +      N +     +   LI    ++F    E   T L + ++L+ ++ E+  ++ EEI  ++GR++ P + ++  +PYT AV+ EI RY  L+P  LPH +T D++   YLI K + +  +  +V  +   +  P+ F P HFL    +G+ K +  D  MPF  G   C+GE   + +LF+ LT+I+QNF +K
Sbjct:   25 GRGRLPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKFNENLRI--------LSSPWIQVCNNFPALIDYLPGSHNKIAENFAYIKSYVLERIKEHQESLD-MNSARDFIDCFLIKMEQEKHNQQ--SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLD--KSGNFKKS--DYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLK 459          

Query:  104 RKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWC-----SEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVF 1525
            RKLP G      IGN++++  + +     N SK++GP+F +  G   +VV      + +   + G   S R    + +     + I+  +   W   R   L  L+NF   ++ + + V EE   L+++++       +   +   +  N++  ++   RF+ + +N+  L +   EN +I N         PW++    F   L  C     ++  +N  +  S+ +E ++EH+   D +N   + ID FL +     +N +    I +  L+    +LF+   E   T L + ++L+ +H E+  ++ EEI  +IGR + P + ++  +PYT AV+ EI RYS LVP  +PH +T D +   YLI K + +     +V  D   +  P+ F P HFL    NG+ K +  D  MPF  G   C GE   + +LF+ LT+I+QNF +K   ++   N+ ++   T G++  P +  + F
Sbjct:   27 RKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNS--------PWIQVCNNF-PLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLD-VNNPRDFIDCFLIKMEQEKDNQKSEFNIEN--LVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLD--KNGNFKKS--DYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAV---TKGIVSLPPSYQICF 487          

Query:   98 GYRKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFL--FWCSEYK--RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFL----KEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            G  KLP G      IGN++++  + +   L N SK++GP+F L  G + +VVL     + +   + G   S R    L E  N    I+F +   W   R   L  L+NF   ++ + + V EE   L+++++       +   +   +  N++  II + RF+ + + +  L E + EN +I        L  PW++    F   +  F  +  K  +N     S+  E ++EH+   D MN  ++ ID FL    KE++N      I        L    ++LF    E   T L ++++L+ +H E+  ++ EEI ++IGR++ P + ++  +PYT AV+ E+ RY  L+P +LPH +T DI+   YLI K + + ++  +V  D   +  P+ F P HFL     G+ K +     MPF  G   C+GE     +LF+ LTSI+QNF +K
Sbjct:   25 GRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKI--------LSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMD-MNNPQDFIDCFLMKMEKEKHNQPSEFTI------ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLD--EGGNFKKS--KYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLK 459          

Query:   92 PIGYRKLPEGKEWSFIGN--LIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIK-NMLIKTMLLFPWLEK-LPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNF----------KIKFRREIT 1450
            P G  +LP      F+GN  L+   +  L   L+ K   +G +F L +G    V+++    I +   +   N   R    + E    +  ++      W  +R   L  L+NF   ++ L E + EE   L + IK+  G+  +       ++ NI+  I    RFE +   ++ L ++++E + ++ +   +   +FPW+ K LP   + LF       N+K    F   +I++H++ ++   +  + IDA+LKE +    N        +  LI + ++LF    E   T L W+++ MA + EIQE++  EI ++IG+ + P+   + S+PYT AVI E+ R  +++P+ +P ++T D  L  Y + K +++  N  A+HRD   W  PD F P+HFL+   NG  K   R+  MPF IG   CLGE+  + +LF+  TS++Q F           +KFR  IT
Sbjct:   44 PPGPWRLP------FLGNFFLVDFEQSHLEVQLFVKK--YGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLF------SNWKKLKLFVSHMIDKHRKDWNPA-ETRDFIDAYLKEMSKHTGNP--TSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLE---NGQFKK--REAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRMGIT 488          

Query:  143 NLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNY-KILNEIIEENSQIKNMLIKTMLLFP-WLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFL----KEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKI 1429
            NL+++ R  L        + +G +F + +G R VV+L     I +   +K    S R    + + +     ++F +   W + R   +  +++F   ++ + E + EE   L+++++   G  ++   LF+    NI+  I+   RF  + + + K+LN   +  S I ++  +   LF  +L+  P   R ++      +N +  N++    +E+H+   D  +  ++LID +L    KE++N           S   L  N + LF    E   T L +  +LM ++  + ER++ EI Q+IG  + P L ++  +PYT+AVI EI R+S L+P+ +PH +T+      Y+I K++ VF+       D   +EKPD F P+HFL    NG +K T  +  +PF +G   CLGE   + +LF+  T+I+QNF +
Sbjct:   42 NLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFSGFLKYFPGAHRQVY------KNLQEINAYIGHSVEKHRETLDP-SAPKDLIDTYLLHMEKEKSNAHSE------FSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLD--ANGALKKT--EAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSM 459          

Query:  104 RKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKG---VNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNF-----ISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERE-SKNYKILNEIIEENSQIKNMLIKTML-LFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFK 1426
            RK P+G     F GNL++   + +  HL   SK +GP F  +      VVL+    I + F  +G   VN ++R P+ILF+ +     ++F     W I+R   LK+L++F     + +EQ +  +   E L  L+ I D   K ++     +  + N++++ +    ++ E +  ++   ++++ + +I       ++  FPWL  LP      +     K N K    F +E +    + +D  ++ EN + A++++    G  N     +    L  + ++ ++   E     L W +  M ++ E+Q+++  EI + IG  ++P++ +K+++PYTQAVI E+ R S++VPI   H  TED+ + E+ I   +L+F   ++V ++  V+E+   F P+ +L +     +  T  +  +PF +G   C+GE   + +LF+I ++++Q ++
Sbjct:   24 RKYPKGPFPLPFFGNLLQFPADNIQEHLDKLSKTYGPCFT-VWTPLPAVVLTDYEHIKEAFVTQGDAFVNRAQRLPEILFQPH-PNTGVVFSSGDNWKIQRRTALKILRDFGLGRNLMEEQVMRSV--HEMLAQLEHISD--KKNVDMYWPIQLCVGNVINESLFGYHYKYEDAGRFEKFVKVVDRHLKIAQGNASLLVSAFPWLRHLPVIGNLGY--HSIKNNIKSYQQFIEEEVTSQLKNYDGESEPENFVHAYMQQMKQTGNPN-----LDMTNLCASVLDFWLAGMETASNSLRWHLAFMMKYPEVQDKVRNEIFENIGTARLPSMSDKQNMPYTQAVIHEVQRCSNMVPILATHMNTEDVLVKEHNIPTGTLLFAQIWSVLKNDPVFEENSKFNPDRYL-MPDGKTLNKTVLERTIPFSVGKRNCVGEGLARMELFLIFSALIQKYE 461          

Query:  107 KLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNL---SERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISK----EQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERE-SKNYKILNEIIEENSQIKNMLIKTMLL---FPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNG-DIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFK 1426
            K P+G     FIGN+ +   + +  +    SK +GP F + +     +VL+    I   F N+G      + R P+ L   ++    IL  D   W ++R   LK+L++F       E+++I  V+E  LI L++I D   K ++     +  + N++++ +    ++ E S+ +K   +I++++  ++++  K  LL   FPWL+ +P      +     K N    ++F +E +    +K+D  ++ EN + A++++    G       G+    L    ++ ++   E     L W +  M ++ E+Q+++ +EI+  +G  ++P++ +K ++PYTQAVI E+ R S+++P    H+  E+ E+H   +   SLVF   ++V R+  V+E P+ F P  +L+  ++G        ++ +PF IG   C+GE   + +LF+I ++++Q ++
Sbjct:   25 KYPKGPLPLPFIGNIHQFPPDNVQKYFDVLSKTYGPCFTIWIPF-PAIVLTDYEHIKDAFVNQGDTFTYRAHRSPETLLPVHD-HTGILASDGDHWRLQRRTSLKILRDFGLGRNLMEEQVIRSVHE-MLIQLENIND--KKNVDVFWPIQLCVGNVINETLFGFHYKYEDSEKFKTFVKIVDKH--LRHLQGKMPLLVSAFPWLKHVPIVGDIGY--HNIKNNISSYHTFIEEEVATQVKKYDGESEPENFVHAYMQQMKQTGN-----PGLDITNLCATVLDFWLAGMETTSNSLRWHLAFMMKYPEVQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPFLGSHQCKEETEIHGNRVPAGSLVFAQLWSVMRNDTVFEDPETFNPSRYLQ--SDGKTFDKAVLEKTIPFSIGKRNCVGEGLARMELFLIFSALIQKYE 461          

Query:  104 RKLPEGK-EWSFIGNLIRLFREPLWSHLYNK-SKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERW----PDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCG---KEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQ-IKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNS---FFKEIIEEHKRKF-DSM--NKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEE 1456
            R+LP G   W   GN+           L+    + +G IF + +G   +V++S   TI K F     + S RW     D + E  N  + I   D   W  +R   L  L++F   +  + +++  E   L+  ++  CG   KE++        + NI++ ++  LRF +++     L++++++ S  +   ++   + FP   K+P          E+ R   I+N    F +  IE H+  + D M   + E+L  A++ E      N   +    D QL    ++LF    E   T L W+ +LMA++ ++Q+ +  E+   IG+  I  + ++  LPY QA I+EI R ++++PI L   + EDIE+  Y  +K  L+      +  D +++E P++F P  FL    + D      DE +PF IG  QCLGE   + +L+++  +++QNF  +   ++T E
Sbjct:   54 RRLPNGPVPWLVAGNMPSFINVNNVDVLFQSWKQQYGGIFTVWIGPIPLVMVSDLPTIKKYFIQHADSFSNRWRNFVTDSIMEGSNGIVQI---DGNKWREQRRFALHTLRDFGVGKPLMEQMITLEVTSLMNHMEKSCGLDGKELHLCPSIAVCVGNIINNMLFGLRFNQDNSYMHRLHQLLDDQSHTVMQPIMGAYIAFPVTSKIP------IINGEWNRLMGIKNELLEFLETQIEGHRMNWKDEMIEQEPEDLTYAYMIEVEKRKRNGEDVGFFDDQQLKMLLLDLFFAGMETTVTTLKWAFLLMAKNQKVQKNVQAELDS-IGQPMI-EIQHRTRLPYVQATINEIQRIANILPINLLRTVAEDIEIDGYNFKKGDLIIPQISILMNDPEIFENPEEFNPSRFL----DEDNNVKKIDEFLPFSIGRRQCLGESLARAELYLVFANLIQNFNFEVADDVTTE 505          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFR-EPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETY-NCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRF-ERESKNYKILNEIIEENS-QIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFD-SMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKI 1429
            P G   LP       IGNL+ L    P +      +  +G I+   +G R  +++SS   + + F   G   +++ P    E++      ++  +  +W   R   +   ++F   + ++ + +  E   +  +     G+ ++  ++F +++ N++++++   RF E  +  ++ +      NS +  +  ++     PW+  +      L    +Y++ +     FF   IE HK++ D  + +  + ++AFLKEQ    E +   +  S  QL    ++L+  A       ++W       + + Q+++HEE+ ++IG ++  N  +K +LPYT A I+EI R ++LVP+ L H  T D  L  Y I K + V      V  D +V+ +P  F PE FL    + D K    ++L+PF +G  QCLGE   + +LF+ + +    +++
Sbjct:   26 PAGPTPLP------LIGNLLSLRNPAPGYKAFARWTAKYGDIYTFWLGTRPYILVSSYEALKETFIKDGETYADKKPMAFQESFRGGSYGVVETNGPFWREHRRFAIHQFRDFGLGKDRMEQRIMLEVEDIFNNCDKTIGEGVDLTDIFDRAVGNVINQMLFGYRFDETRADEFRTIRAFFNFNSGEFASFSMRVQFFLPWMGYIMPGPTILDRFKKYQKGF---TEFFGTQIENHKKEIDFELEENSDYVEAFLKEQRKR-EASGDFESFSTKQLSNMCLDLWFAALMTTSNTMTWCFAYTLNYLDAQQKLHEELDRVIGSERHINTADKPNLPYTNAYINEIQRTANLVPLNLLHMTTRDTVLKGYNIPKGTGVVAQISTVMYDENVFPEPYIFKPERFL----DDDGKLKKVEQLVPFSVGKRQCLGEGLARMELFLFIANFFNRYRV 462          

Query:  107 KLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKG---VNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNF-----ISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERE-SKNYKILNEIIEEN-SQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFK 1426
            K P+G     FIGN++++  E +  +L + SK +GP F L       +VL+    + + F  +G   +  ++R P+ L + +     +LF +   W  +R   LK+L++F     + +EQ +  +   E L  L+ I D   K ++     +  + N++++ + +  ++ E SK ++   ++++++   ++   I  M  FPWL+  P      +     K+N +    F  + +    + +D  ++ EN + A++++    G  N  ++      L  + I+ ++   E     L W +  M ++ EIQ+++ +EI+  +G  ++P++ +K ++PYTQAVI E+ R S+++PI   H   +DI L    I   +LVF   ++V ++  V+E+   F P+ +L +     I  +  +  +PF +G   C+GE   + +LF+I ++++Q ++
Sbjct:   25 KYPKGPFPLPFIGNILQIPSENIQEYLDDLSKTYGPCFTLWTPL-PAIVLTDYEHVKEAFVTQGDAFIYRADRPPETLLQPH-LNTGVLFSNGDNWRFQRRTALKILRDFGLGRNLMEEQVMRSV--HEMLAQLERIAD--KKNVDMFWPIQLCVGNVINESLFSYHYKYEDSKKFETFVKVLDKHLKTVQGKTIFLMSAFPWLKHFPVIGELGY--HRIKKNIQSYQEFINDEVTSQIKHYDGESEPENFVHAYMQQMKQSGNPNLDMN-----NLCASVIDFWLAGMETTSNSLRWHLAFMMKYPEIQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPILGTHTNRDDILLKGKKIPTGTLVFAQIWSVLKNDPVFEESSKFNPDRYL-MADGKTINKSVLERTIPFSVGKRNCVGEGLARMELFLIFSALIQKYE 461          

Query:  104 RKLPEGKEWSF--IGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFI-----SKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNML-----IKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKE---QNNLGENNRIIDGIS-DWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKF 1435
            RKLP G  W    IG L+ +  E   +     +K +G +F   +G +  VV+S    I + F+ +    + R PD  F        I+      W  +R  +   L+ F      + +Q++ + +  E    +  +    G+ ++   +   ++ N++  ++++ RF  +   ++  N +IEE  ++   +     I TM  FP +             ++  +N      F++++I++HKR FD  N + +L+D +L E       G +  + DG + + QL++  I+LF    E I+T L W  V M R+ +   R+ +E+ Q++GR ++P + + + LP T++ I E  R SS+VP+   H  T D+EL+ Y I   S V     +VH D ++WEKP++F P  F+   T G ++    +  +PFG+G   CLG+   + +LF+   S +  F I  
Sbjct:   51 RKLPPGP-WGLPVIGYLLFMGSEK-HTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGR-PDTPFMQTLNGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAK---------NKIAQNRAEMQRFYQDVIDDHKRSFDP-NNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFID--TEGKVRKP--EYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIAL 491          

Query:  104 RKLPEGKEWSF--IGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFI-----SKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNML-----IKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKE---QNNLGENNRIIDGIS-DWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKF 1435
            RKLP G  W    IG L+ +  E   +     +K +G +F   +G +  VV+S    I + F+ +    + R PD  F        I+      W  +R  +   L+ F      + +Q++ + +  E    +  +    G+ ++   +   ++ N++  ++++ RF  +   ++  N +IEE  ++   +     I TM  FP +             ++  +N      F++++I++HKR FD  N + +L+D +L E       G +  + DG + + QL++  I+LF    E I+T L W  V M R+ +   R+ +E+ Q++GR ++P + + + LP T++ I E  R SS+VP+   H  T D+EL+ Y I   S V     +VH D ++WEKP++F P  F+   T G ++    +  +PFG+G   CLG+   + +LF+   S +  F I  
Sbjct:   51 RKLPPGP-WGLPVIGYLLFMGSEK-HTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGR-PDTPFMQTLNGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAK---------NKIAQNRAEMQRFYQDVIDDHKRSFDP-NNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFID--TEGKVRKP--EYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIAL 491          

Query:  215 FKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILF---ETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKD----VCGKE--INTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKL-PKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRS-LPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKI 1429
            + L +G  +VV+  +N+ I ++  N+ ++     PD +F    T+N  + +L  D   W  +R  IL+ LKNF      +++IV+ E   LL+D+KD      GK+  I   +L    ++N L  ++   R+E  S     L E   E  +  +M+      FP L  + P F  +  +   ++  Y    +F  + IE H+  + + ++  +L+D++L+ Q+   E N      SD  L+   +++F+   E     L +  + +    EIQER  +EI +++G ++IP     R+ LPY +A+  E  R   L    +PH+   D  L  Y I K+++V   F  +  +   +  P+ F P+ +   L +G +K    +   PFG G  +C+G+   +  LF+  T+++QNFK+
Sbjct:   71 YGLKIGKDKVVIAYTNDAISEMMTNEDIDGR---PDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLY----TFMSKEIELHRLTYKNYDEPRDLMDSYLRAQD---EGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRY---LFDGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:  215 FKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILF---ETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKD----VCGKE--INTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKL-PKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRS-LPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKI 1429
            + L +G  +VV+  +N+ I ++  N+ ++     PD +F    T+N  + +L  D   W  +R  IL+ LKNF      +++IV+ E   LL+D+KD      GK+  I   +L    ++N L  ++   R+E  S     L E   E  +  +M+      FP L  + P F  +  +   ++  Y    +F  + IE H+  + + ++  +L+D++L+ Q+   E N      SD  L+   +++F+   E     L +  + +    EIQER  +EI +++G ++IP     R+ LPY +A+  E  R   L    +PH+   D  L  Y I K+++V   F  +  +   +  P+ F P+ +   L +G +K    +   PFG G  +C+G+   +  LF+  T+++QNFK+
Sbjct:   71 YGLKIGKDKVVIAYTNDAISEMMTNEDIDGR---PDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLY----TFMSKEIELHRLTYKNYDEPRDLMDSYLRAQD---EGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRY---LFDGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:  353 NILFKDKAWWTIRRSLILKVLKNF-ISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIK-----NMLI----------KTMLLFPWLEKL-PKFVRFLFWCSEYKRNYK--IQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPR-DELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSP 1504
             I F+D   W  +R  IL+ L++F   +    +E+V +E L  + D+     K  +  E+ +     +L  ++ N  F   +  Y + NE +      K      M I          K + + PW+  + P+      W    K N        FF + ++++   ++   +  N +D ++ E    G       G +  QLI   ++    AF  I   LS  +  +  +  +  R+  EI +++G  ++PNL ++++LP+T+A I E  R  +LVP  +PHK  ED EL  Y I K+++V  + YA H D  +W  P+ F PE FL    + D K   + D  +PFG G   C GE F +  LF++  ++ Q+F          +    +    NG+I SP
Sbjct:  116 GIFFQDGPLWKEQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFN-PFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPE------WSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVE-RNFMDVYIAEMRR-GPGY----GFNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFL----DADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLG---PNDRLPDLSQNLNGLIISP 499          

Query:  101 YRKLPEG-KEWSFIGNLIRLFREPL----------------------WSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKA-WWTIRRSLILKVLKNFISKEQKLIEIVNEECLIL---LKDIKDVCGKE-INTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIK-NMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFL-----KEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 1534
            Y  +P G K W  +GN       P                        + L   SK++G IF + +G + +VVL+  + +     N     S+R    L         I+F      W   R      L++F      L   ++E   I+   L+ + +  G   I+   L   ++ NI+S + +  RF  E K ++ + +++    +I  N  I  + +FPWL  LP  V       E +R      +F K II  H+   D  N   + ID +L     K++    E N      S+  L     +LFI   +     + WS++ M+ + ++QE++ +EI  ++G +++P+L +K SLPYT+A I E+ R + +VP+++PH  +E  E   + I K +++  N ++VHRD  VWE PDDF P  FL    +   K   +D  +PFG+G   C+GE+  K +LF++ TS++Q F  +F    T  +    +H   G+  +P    V  + R
Sbjct:   40 YANIPPGPKPWPIVGNFGGFLVPPFILKRFVKNSKEFAKVVSNPLSPQAGLIEMSKLYGNIFSIFVGPQLMVVLTGYDAVRDAMLNHTETFSDRPHIPLVTIITKRKGIVFAPYGPLWRTNRRFCHSTLRSFGFGRMSLEPCIHEGLAIIKTELQSLIETAGPSGIDLTPLISNAVSNIISLMSLGQRFHHEDKEFRNMRDLMSHGLEISVNTSILLVNVFPWLYYLPFGV-----FKELRRAELDITAFLKRIIARHRATLDPENP-RDFIDMYLVEMLAKQKEGSSEENLF----SEDDLFYIIGDLFIAGTDTTTNSMLWSILYMSLYPDVQEKVQKEIDAVVGSERVPSLTDKSSLPYTEATIMEVIRMTVVVPLSIPHMASETTEFRGFTIPKGTVIIPNLWSVHRDPTVWENPDDFNPSRFL----DDQGKILRKDCFIPFGLGRRVCMGEQLAKMELFLMFTSLMQTFTFRFPEGATAPS----MHGRFGLTLAPCPFTVCVKTR 533          

Query:  173 WSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQ-IKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSF--FKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIG-RDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPL 1507
            +  L+  SK +GP++ + MG R VVVLS    + +   N      ER    +F+ +N    I+F +   W   R   L  L++F   +++  E++ EE   L ++I+   GK   TK     ++ N+++ I+ ++RFE  S  +        EN++ + +  ++   +FPWL         LF  ++ +    +Q SF    EI+   K+  +  +    + D FL +Q    E+ +     +    +     LF    +   T L W ++L+A++ EIQ ++H+EI  +IG R  +P+  ++++LPYT AVI EI R++ ++PI L  + + D+ L+ YLI+K + VF    +V RD + WE PD F P+HFL    N   ++  +D  MPFG G   C+GE   + +LF+  TS++Q+F       ++E+  +  L    G   SP+
Sbjct:   62 YMSLWKLSKQYGPVYTVHMGPRTVVVLSGYKAVKEALVNLSEEFGERDISPIFQDFNEGYGIVFSNGENWKEMRRFALSNLRDFGMGKKRSEELITEEIKYLKEEIERFGGKPFETKLPLAMAISNVIALIVYSIRFEYNSPKFHRAIVRANENAKLVGSPSVQLYNMFPWLR--------LFVANQKRVVDNVQESFKQIGEIVNGLKKTLNPQSP-RGIADKFLIQQQKDKESGKTDSLYNSNNFLTTINNLFGAGIDTTVTTLRWGLLLIAKYPEIQAKVHDEIDSVIGERQPVPD--DRKNLPYTDAVIHEIQRFADILPIGLLRQTSCDVYLNGYLIKKGTSVFPLIASVLRDENEWETPDSFNPKHFL----NKQGQFVKKDAFMPFGAGRRLCIGESLARMELFLFFTSLLQHFCFTPPPGVSEDELD--LTPVVGFTLSPM 493          

Query:  194 SKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPD----ILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFE-RESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQN--SFFK---EIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEEN 1459
            SK +GPI+ + +G ++VV+LS      K+ K   VNLSE + D     +F  +N    I F +   W   R   L  L++F    ++  E++ EE   + ++ +   G    TK     ++ NI++ I+ ++RFE   +K ++++    E      +  ++   +FPWL  +              RN  ++N    FK   E+I    +  D  N    ++D+FL  Q    E+ +     +   L      LF    +   T L W ++LMA++ EIQ ++ +EI ++IG  + P + ++++LPYT AVI EI R++ + PI  P + T D+ L+ Y I+K + VF    +V RD + WE PD F P+HFL    N   ++  +D  MPFG G   C+GE   + +LF+  TS++Q F+      ++E++
Sbjct:   71 SKKYGPIYTVYLGPKKVVILSG----YKIVKEALVNLSEEFGDRDISPIFHDFNRGYGIAFSNGENWREMRRFALSTLRDFGMGRKRSEELIIEEIKYVKEEFEKFGGNPFETKLPLALAISNIIASIVFSVRFEYSNTKLHRMVGRAYENMKLTGSPSVQIYNMFPWLRPIVA-----------NRNQIVKNLRDTFKQNEELINGVMKTLDPFNP-RGIVDSFLIRQQKDEESGKTDSLYNSNNLYCTVNNLFGAGTDTTVTTLRWGLLLMAKYPEIQAKVQDEIERVIG-GRQPVVEDRKNLPYTDAVIHEIQRFADISPIGAPRQTTCDVHLNGYFIKKGTPVFPLLVSVLRDENEWETPDSFNPKHFL----NKQGQFVKKDAFMPFGAGRRVCIGESLARMELFLFFTSLLQYFRFTPPPGVSEDD 481          

Query:  194 SKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPD----ILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFE-RESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQN--SFFK---EIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEEN 1459
            SK +GPI+ + +G ++VV+LS      K+ K   VNLSE + D     +F  +N    I F +   W   R   L  L++F    ++  E++ EE   + ++ +   G    TK     ++ NI++ I+ ++RFE   +K ++++    E      +  ++   +FPWL  +              RN  ++N    FK   E+I    +  D  N    ++D+FL  Q    E+ +     +   L      LF    +   T L W ++LMA++ EIQ ++ +EI ++IG  + P + ++++LPYT AVI EI R++ + PI  P + T D+ L+ Y I+K + VF    +V RD + WE PD F P+HFL    N   ++  +D  MPFG G   C+GE   + +LF+  TS++Q F+      ++E++
Sbjct:   71 SKKYGPIYTVYLGPKKVVILSG----YKIVKEALVNLSEEFGDRDISPIFHDFNRGYGIAFSNGENWREMRRFALSTLRDFGMGRKRSEELIIEEIKYVKEEFEKFGGNPFETKLPLALAISNIIASIVFSVRFEYSNTKLHRMVGRAYENMKLTGSPSVQIYNMFPWLRPIVA-----------NRNQIVKNLRDTFKQNEELINGVMKTLDPFNP-RGIVDSFLIRQQKDEESGKTDSLYNSNNLYCTVNNLFGAGTDTTVTTLRWGLLLMAKYPEIQAKVQDEIERVIG-GRQPVVEDRKNLPYTDAVIHEIQRFADISPIGAPRQTTCDVHLNGYFIKKGTPVFPLLVSVLRDENEWETPDSFNPKHFL----NKQGQFVKKDAFMPFGAGRRVCIGESLARMELFLFFTSLLQYFRFTPPPGVSEDD 481          

Query:  104 RKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML-LFPWLEKLPKFVRFLFW--CSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEE 1456
            ++ P  K    +GNL+ L     +   +  SK +G +F++ +G  + VVL    T+ +   N      +R     F   N E  ILF +   W   R   L  L++F   ++   E + EE   L  +     GK  +T +    ++ NI+S I+   RFE     +  + +   EN ++   +   +  +FPWL    K  R +         +  K+  +  + +     R F         +D+FL  + +  ++ +      +  L+     LFI   +   T L W ++LMA++  IQ+R+ EEI ++IG  + P + +++ LPYT AVI EI R +++VP++LPH+ T DI  + Y I+K + V     +V +D   WEKP+ FYPEHFL    +   ++  RD  MPF  G   CLGE   + +LF+  TS++Q+++      ++E+
Sbjct:   43 KEPPGPKPLPLVGNLLTLDLTRPFDTFFKLSKTYGNVFQVYLGPEKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMNDEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMWLYDIFPWLGPFLKNKRIIVENIIQSRVQMTKLITALLETLNPNDPRGF---------VDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIG-GRQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFL----DEKGQFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSED 482          

Query:  113 PEGKEWSFIGNLIRL-FREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSE-YKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            P  K    IGN+  +  + P  ++L    K +GPIF++ +G +++VVL    T+     N     SER    +F     E  I+F     W + R   L  L++F    + + + +NEEC  L++  K   GK  +   +   ++ NI+  I++  RF+ +   +  L  +I EN ++      T++L+      P  +R+L    +   +N      F +E   +HK K D +N   NL+DAFL +Q     N       +   L+ N   LF+   E   T + W ++LM ++ EIQ+ +  EI ++IG+ + P   +++S+PYT AVI EI R+ +++P+ LPH   +D+    Y + K + V     +V  D   +EKP +FYP+HFL    + +  +   +  +PF  G   C GE   K +LF+  TS++QNF  +
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYL-ELWKKYGPIFRVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVVPIFLDVVKEYGIIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPKFLRLMSLINENLRLTGS--PTVMLY---NVFPSVMRWLPGNHQTVGKNAAENQRFIRETFIKHKEKLD-VNDQRNLVDAFLVKQQEKKGNAVYFHDDNLTMLVSN---LFVAGMETTSTSVRWGLLLMMKYPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFL----DSEGNFVKNEAFLPFSAGKRSCAGENLAKMELFLFFTSLLQNFTFQ 462          

Query:  113 PEGKEWSFIGNLIRL-FREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSE-YKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            P  K    IGN+  +  + P  ++L    K +GPIF++ +G +++VVL    T+     N     SER    +F     E  I+F     W + R   L  L++F    + + + +NEEC  L++  K   GK  +   +   ++ NI+  I++  RF+ +   +  L  +I EN ++      T++L+      P  +R+L    +   +N      F +E   +HK K D +N   NL+DAFL +Q     N       +   L+ N   LF+   E   T + W ++LM ++ EIQ+ +  EI ++IG+ + P   +++S+PYT AVI EI R+ +++P+ LPH   +D+    Y + K + V     +V  D   +EKP +FYP+HFL    + +  +   +  +PF  G   C GE   + +LF+  TS++QNF  +
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYL-ELWKKYGPIFRVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVVPIFLDVVKEYGIIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPKFLRLMSLINENLRLTGS--PTVMLY---NVFPSVMRWLPGNHQTVGKNAAENQRFIRETFIKHKEKLD-VNDQRNLVDAFLVKQQEKKGNAVYFHDDNLTMLVSN---LFVAGMETTSTSVRWGLLLMMKYPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFL----DSEGNFVKNEAFLPFSAGKRSCAGENLARMELFLFFTSLLQNFTFQ 462          

Query:  113 PEGKEWSFIGNLIRL-FREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSE-YKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            P  K    IGN+  +  + P  ++L    K +GPIF++ +G +++VVL    T+     N     SER    +F     E  I+F     W + R   L  L++F    + + + +NEEC  L++  K   GK  +   +   ++ NI+  I++  RF+ +   +  L  +I EN ++      T++L+      P  +R+L    +   +N      F +E   +HK K D +N   NL+DAFL +Q     N       +   L+ N   LF+   E   T + W ++LM ++ EIQ+ +  EI ++IG+ + P   +++S+PYT AVI EI R+ +++P+ LPH   +D+    Y + K + V     +V  D   +EKP +FYP+HFL    + +  +   +  +PF  G   C GE   + +LF+  TS++QNF  +
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYL-ELWKKYGPIFRVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVVPIFLDVVKEYGIIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPKFLRLMSLINENLRLTGS--PTVMLY---NVFPSVMRWLPGNHQTVGKNAAENQRFIRETFIKHKEKLD-VNDQRNLVDAFLVKQQEKKGNAVYFHDDNLTMLVSN---LFVAGMETTSTSVRWGLLLMMKYPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFL----DSEGNFVKNEAFLPFSAGKRSCAGENLARMELFLFFTSLLQNFTFQ 462          

Query:  113 PEGKEWSFIGNLIRL-FREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSE-YKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFL-KEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            P  K    IGNL  +  ++P  + +    K +G +F + +G  +VVVL   +T+     N     SER    +FE ++  + ++F     W + R   L  L++F   ++ + E ++EE   L++ IK   GK  +   +   ++ NI+  I++N RF+ +      L  I+ +N +I    I  ++L+      P  VR++    +    N      F +E   +H+ + D +N   +LIDAFL K+Q     + +     +   L+ N   LF+   E   T L W ++LM ++ +IQ+++ +EI ++IG  + P L +++ +PYT AVI EI R++++ PI+LPH  T D+    Y I K++ V +   +V +D D ++KP++FYPEHFL    N    +   +  +PF  G   C GE   K +LF+  T ++QNF  +
Sbjct:   32 PGPKPLPLIGNLHMMNMKKPHLTFMELAEK-YGSVFSVHLGTEKVVVLCGTDTVRDALINHAEEFSERAKMPIFEDFSKGLGVVFGHGENWKVMRRFTLSTLRDFGMGKKTIEERISEESDCLVETIKSYEGKPFDNTLIMNAAVANIIVHILLNHRFDYQDPTLLKLINIVIDNIKIGGSPI--VMLY---NTYPSVVRWIPGSHKTLGENTAQLYKFLEETFTQHREQLD-VNDQRDLIDAFLVKQQEEKPSSAKFFHNENLVALLAN---LFVAGMETSSTTLRWGLLLMMKYPDIQKKVQDEIDKVIGSAE-PRLEHRKLMPYTDAVIHEIQRFANIAPISLPHATTTDVTFRGYFIPKDTQVMIVLTSVLQDKDYFKKPEEFYPEHFL----NSKGNFVKNEAFLPFSAGRRICAGETLAKMELFLFFTKLLQNFTFQ 459          

Query:  101 YRKLPEG-KEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSE-YKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            Y+  P G K    IGN+  L R+  +       K +G IF + +G +++VVL    T+     N G   SER    +F        ++F     W + R   L  L++F   ++ + + +NEEC  L++ ++   GK          ++ NI+  +++  RF+ E   +  L  ++  N+  + M    ++L+      P  +R+L    +   +N      F +E   + + K D +N   NLIDAFL  Q    E+       +   L+ N   LF    E   + L W ++LM ++ EIQ+ +  EI ++IG+ + P   +++S+PYT AVI EI R+ +++P+ LPH   +D+    Y + K + V     +V  D D +EKP++FYP+HFL    + +  +   +  +PF  G   C GE   K QLF+  TS++QNF  +
Sbjct:   31 YQHFPPGPKPLPIIGNIHILNRKRPYLTFLELWKKYGSIFSVQIGSQKMVVLCGYETVKDALVNHGEEFSERPEIPIFHVIAKGYGVIFSHGENWKVMRRFTLSTLRDFGMGKKSIEDKINEECDSLVEKLRSYGGKAFENSVTINAAVANIIVSLLLGRRFDYEDPTFLRLMSLM--NANFRLMGSPMVMLY---NLYPSIIRWLPGSHKTVGKNAAETQRFIRETFTKRREKLD-VNDQRNLIDAFLVRQQETKEDGCYFHDDNLTVLVSN---LFAAGMETTSSTLRWGLLLMMKYPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTYVIPLLTSVLYDKDHFEKPNEFYPQHFL----DSEGNFVRNEAFLPFSAGKRSCAGENLAKMQLFLFFTSLLQNFTFQ 462          

Query:   98 GYRKLPEG-KEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYK----RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            G  +LP G K    +GNL++L  + L + L   SK +G +F + +G R V+VLS   T+ +   +KG   S R    +F  +     I F D   W I R   +++L+NF   ++ + E + EE   LL+ ++ + GK  +   +  +S+ NI+  ++   RF+ + +    +   I +N +I +         PW E    F   L W         RN+          + EH+   D  N   + ID FL +     E    +   +   L+     L     E + T L  + +++ ++ ++Q R+ EEI +++GR ++P L ++ S+PYT AVI E+ R++ ++P+ LPH++T D     +LI K + V      VH D D ++ P +F PEHFL    N   K +P    MPF  G   CLGE   + +LF+  TSI+QNF ++
Sbjct:   26 GKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSS--------PWGEMYNIFPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDP-NSPRDFIDCFLTKMAQ--EKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLD--DNHSFKKSP--AFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQ 460          

Query:   98 GYRKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWC--SEYK--RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVV 1522
            G   LP G   +  IGN +++  + +   L N SK +GP+F L +G R  VVL     + +   + G   S+R    + E  N  + I+F +   W   R   L  L+N    ++ + + V EE   L+++++   G   +   +   +  N++  II   RF+ + K++ +L E + EN +I        L  PWL+    F   + +C  S +K  +N K   S+  E I+EH+   D  N   + ID +L +Q       +    + +     N   LF    E   T L ++++L+ ++ ++  ++ EEI  +IGR + P + ++  +PYT A+I E+ R+ +LVP  +P  +T DI+   YLI K + V  +  +V  D   +  P+ F P HFL    NG+ K +  D  MPF  G   C GE   + +LF+ LT+I+QNFK+K    +       ++   NG+I  P +  V 
Sbjct:   25 GRGSLPPGPTPFPIIGNFLQIDIKNVSQSLTNFSKAYGPVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKINNGLGIVFSNGNRWKEIRRFTLTTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYKDKDFLMLMEKLNENVKI--------LSSPWLQVCNNFPLLIDYCPGSHHKVLKNVKYIRSYLLEKIKEHQESLDVTNP-RDFIDYYLIKQKQANHIQQAEFSLENLACTIN--NLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRSPCMQDRNHMPYTDAMIHEVQRFINLVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLD--ANGNFKKS--DHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLK---SLVHPKDIDMIPFVNGLIALPPHYQVC 486          

Query:  107 KLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWC--SEYK--RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVF 1525
            +LP G   +  IGN +++  +     L N SK +GP+F L +G R +VVL     + +   + G   S R    + E  N  + I F +   W   R   L  L+N    ++ + + V EE   L+++++   G   +   +   +  N++  II   RF+ + K++ +L + + EN +I        L  PWL+    F   + +C  S +K  +N+K   S+  E ++EH+   D  N   + ID FL +Q       +    + +     N   LF    E   T L ++++L+ ++ ++  ++ EEI  ++GR + P + ++  +PYT A+I E+ R+ +LVP  LPH +T DI+   Y+I K + V  +  +V  D   +  P+ F P HFL    NG+ K +  D  M F  G   C GE   + +LF+ILT+I+QNFK+K    +       ++   NG+I  P +  + F
Sbjct:   28 RLPPGPTPFPIIGNFLQIDVKNFNQSLTNFSKTYGPVFTLYLGSRPIVVLHGYEAVKEALIDHGEEFSGRENIPMSEKINNGLGITFSNGNSWKETRRFTLMTLRNLGMGKRNIEDRVREEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYKDKDFLMLMKKLNENVKI--------LSSPWLQVCNNFPLLIDYCPGSHHKVLKNFKYIRSYLLEKVKEHQESLDVTNP-RDFIDYFLIKQKQANHIEQAEYSLENLVCTIN--NLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVVGRHRSPCMQDRSRMPYTDAMIHEVQRFINLVPNNLPHAVTCDIKFRNYIIPKGTTVVTSLTSVLHDSKEFPNPEMFDPGHFLD--ANGNFKKS--DYFMTFSAGKRVCAGEGLARMELFLILTTILQNFKLK---SLVHPKDIDMIPFVNGLITLPPHYQLCF 487          

Query:  104 RKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKR----NYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVF 1525
            R LP G      IGN+++L  + +   L N SK++GP+F L +G    VVL     + + F + G   + R    +F+ +     ++F     W   R   L  L+NF    + + + + EE   L+ +++   G+  +   +   +  N++  I+   RF+ + + +    +I+ EN +I        L  PW++    F   + +     R    N+     +F   +++H+   D +N   + ID FL +      N +     +   L+    +LF    E   T L +S++L+ ++ E+  ++ EEI  +IGR + P + ++ S+PYT AV+ EI RY  L+P +LPH +T D++  EYLI K + V  +  +V  D   +  P+ F P HFL    +   K+   D   PF  G   C+GE   + +LF+ LT+I+QNF +K   ++ + ++  +    NG    P    + F
Sbjct:   27 RNLPPGPTPLPIIGNILQLDLKDISKSLRNFSKVYGPVFTLYLGRNPAVVLHGYEAVKEAFTDHGEEFAGRGVFPVFDKFKKNCGVVFSSGRTWKEMRRFSLMTLRNFGMGRRSIEDRIQEEARCLVDELRKTKGEPCDPTFILGCAPCNVICSIVFQNRFDYKDQEFLTFLDILNENVEI--------LSSPWIQICNNFPAVIDYLPGRHRKLHKNFAFAEHYFLSKVKQHQESLD-INNPRDFIDCFLIKMEQEKHNPKT--EFTCENLVFTASDLFAAGTETTSTTLRYSLLLLLKYPEVTAKVQEEIDCVIGRHRSPCMQDRHSMPYTDAVLHEIQRYIDLLPTSLPHAVTRDVKFREYLIPKGTTVIASLTSVLYDDKEFPNPEKFDPSHFL----DERGKFKKSDYFFPFSTGKRICVGEGLARAELFLFLTTILQNFNLKSPVDLKDLDTTPV---ANGFASVPPKFQICF 487          

Query:   98 GYRKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWC--SEYK--RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGI-ELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            G  KLP G      IGN +++  + +     N SK +GP+F L +G +  V+L     + +   ++G   + R    + E       ++F +   W   R   L  L+N    ++ + + V EE   L+++++   G   +   +   +  N++  II   RF+ + K + IL + I EN +I        L  PWL+    F   + +C  S +K  +N+    S+  E I+EHK   D  N   + ID +L +Q  +   N I       + + + I +LF    E   T L ++++L+ ++ ++  ++ EEI +++GR + P + ++  +PYT A+I E+ R+  L+P +LPH +T DI+  +YLI K + V  +  +V  D   +  P+ F P HFL    NG+  +   D  MPF  G   C GE   + +LF+ILT+I+QNFK+K
Sbjct:   25 GRGKLPPGPTPLPIIGNFLQIDVKNISQSFTNFSKAYGPVFTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLILMDKINENVKI--------LSSPWLQVCNSFPSLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLDVTNP-RDFIDYYLIKQKQV---NHIEQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSPCMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSKEFPNPEMFDPGHFL----NGNGNFKKSDYFMPFSTGKRICAGEGLARMELFLILTTILQNFKLK 459          

Query:   98 GYRKLPEG-KEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYK----RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKI 1429
            G  +LP G K    +GNL++L  + L + L   SK +G +F + +G R V+VLS   T+ +   +KG   S R    +F  +     I F D   W I R   +++L+NF   ++ + E + EE   LL  ++   GK  +   +  +S+ NI+  +I   RF+ + +    +   I +N QI +         PW E    F   L W         RN+          + EH+   D  N   + ID FL +   + E    +   +   L+     L     E + T L  + +++ ++ ++Q R+ EEI  ++GR ++P L ++ S+PYT AVI E+ R++ ++P+ LPH++  D     +LI K + V      VH D D ++ P +F PEHFL    N   K +P    MPF  G   CLGE   + +LF+ LTSI+QNF +
Sbjct:   26 GKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSKDYGSVFTVYLGPRRVIVLSGYQTVKEALVDKGEEFSGRGSYPIFFNFTKGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLDVLRKTEGKPFDPVFILSRSVSNIICSVIFGSRFDYDDERLLTIIHFINDNFQIMSS--------PWGEMYNIFPSLLDWVPGPHRRVFRNFGGMKDLIARSVREHQDSLDP-NSPRDFIDCFLTKM--VQEKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDCVVGRSRMPTLEDRASMPYTDAVIHEVQRFADVIPMNLPHRVIRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLD--ANQSFKKSP--AFMPFSAGRRLCLGEPLARMELFIYLTSILQNFTL 459          

Query:   98 GYRKLPEG-KEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYK----RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            G  +LP G K    +GNL++L  + L + L   SK +G +F + +G R V+VLS   T+ +   +KG   S R    +F  +     I F D   W I R   +++L+NF   ++ + E + EE   LL+ ++ + GK  +   +  +S+ NI+  ++   RF+ + +    +   I +N +I +         PW E    F   L W         RN+          + EH+   D  N   + ID FL +     E    +   +   L+     L     E + T L  + +++ ++ ++Q R+ EEI +++GR ++P L ++ S+PYT AVI E+ R++ ++P+ LPH++T D     +LI K + V      VH D D ++ P +F PEHFL    N   K +P    MPF  G   CLGE   + +LF+  TSI+QNF ++
Sbjct:   26 GKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSS--------PWGEMYNIFPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDP-NSPRDFIDCFLTKMAQ--EKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLD--DNHSFKKSP--AFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQ 460          

Query:   98 GYRKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWC--SEYK--RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVV 1522
            G   LP G   +  IGN +++  + +   L N SK +GP+F L +G R  VVL     + +   + G   S+R    + E  N  + I+F +   W   R   L  L+N    ++ + + V EE   L+++++   G   +   +   +  N++  II   RF+ + K++ +L E + EN +I        L  PWL+    F   + +C  S +K  +N K   S+  E I+EH+   D  N   + ID +L +Q       +    + +     N   LF    E   T L ++++L+ ++ ++  ++ EEI  +IGR + P + ++  +PYT A+I E+ R+ +LVP  +P  +T DI+   YLI K + V  +  +V  D   +  P+ F P HFL    NG+ K +  D  MPF  G   C GE   + +LF+ LT+I+QNFK+K    +       ++   NG+I  P +  V 
Sbjct:   25 GRGSLPPGPTPFPIIGNFLQIDIKNVSQSLTNFSKAYGPVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKINNGLGIVFSNGNRWKEIRRFTLTTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYKDKDFLMLMEKLNENVKI--------LSSPWLQVCNNFPLLIDYCPGSHHKVLKNVKYIRSYLLEKIKEHQESLDVTNP-RDFIDYYLIKQKQANHIQQAEFSLENLACTIN--NLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRSPCMQDRNHMPYTDAMIHEVQRFINLVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLD--ANGNFKKS--DHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLK---SLVHPKDIDMIPFVNGLIALPPHYQVC 486          

Query:  107 KLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWC--SEYK--RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVF 1525
            +LP G   +  IGN +++  +     L N SK +GP+F L +G R +VVL     + +   + G   S R    + E  N  + I F +   W   R   L  L+N    ++ + + V EE   L+++++   G   +   +   +  N++  II   RF+ + K++ +L + + EN +I        L  PWL+    F   + +C  S +K  +N+K   S+  E ++EH+   D  N   + ID FL +Q       +    + +     N   LF    E   T L ++++L+ ++ ++  ++ EEI  ++GR + P + ++  +PYT A+I E+ R+ +LVP  LPH +T DI+   Y+I K + V  +  +V  D   +  P+ F P HFL    NG+ K +  D  M F  G   C GE   + +LF+ILT+I+QNFK+K    +       ++   NG+I  P +  + F
Sbjct:   28 RLPPGPTPFPIIGNFLQIDVKNFNQSLTNFSKTYGPVFTLYLGSRPIVVLHGYEAVKEALIDHGEEFSGRENIPMSEKINNGLGITFSNGNSWKETRRFTLMTLRNLGMGKRNIEDRVREEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQDRFDYKDKDFLMLMKKLNENVKI--------LSSPWLQVCNNFPLLIDYCPGSHHKVLKNFKYIRSYLLEKVKEHQESLDVTNP-RDFIDYFLIKQKQANHIEQAEYSLENLVCTIN--NLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVVGRHRSPCMQDRSRMPYTDAMIHEVQRFINLVPNNLPHAVTCDIKFRNYIIPKGTTVVTSLTSVLHDSKEFPNPEMFDPGHFLD--ANGNFKKS--DYFMTFSAGKRVCAGEGLARMELFLILTTILQNFKLK---SLVHPKDIDMIPFVNGLITLPPHYQLCF 487          

Query:   98 GYRKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWC--SEYK--RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGI-ELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            G  KLP G      IGN +++  + +     N SK +GP+F L +G +  V+L     + +   ++G   + R    + E       ++F +   W   R   L  L+N    ++ + + V EE   L+++++   G   +   +   +  N++  II   RF+ + K + IL + I EN +I        L  PWL+    F   + +C  S +K  +N+    S+  E I+EHK   D  N   + ID +L +Q  +   N I       + + + I +LF    E   T L ++++L+ ++ ++  ++ EEI +++GR + P + ++  +PYT A+I E+ R+  L+P +LPH +T DI+  +YLI K + V  +  +V  D   +  P+ F P HFL    NG+  +   D  MPF  G   C GE   + +LF+ILT+I+QNFK+K
Sbjct:   25 GRGKLPPGPTPLPIIGNFLQIDVKNISQSFTNFSKAYGPVFTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLILMDKINENVKI--------LSSPWLQVCNSFPSLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLDVTNP-RDFIDYYLIKQKQV---NHIEQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSPCMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSKEFPNPEMFDPGHFL----NGNGNFKKSDYFMPFSTGKRICAGEGLARMELFLILTTILQNFKLK 459          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLF-WCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVF 1525
            P G ++ P       +G +I   +EP+ ++L   SK HGPIF++ +G R+V++LS+ + I K   + G N S RW   L      +  I+FKD   W+ +RS +LKVL++F   + K +++V  EC  LL++++ + GK I+  ++      NI+SK I+N RFERE+     + +++ E  + K+++    ++FP  +    F   +  + S++K   +IQN +FKE I+EH +  D  ++ E+L+D FL +QN L + N  +   +DWQLIR+ +ELF   +E   T L WS + M++H +IQ+++H EII++IG++++P + +K+S+ YTQAV+DEIFR SS+ P+ L H+   D  +  Y I KN+L+F N YA H D D+WEKP  FYPEHFL    NG++KYTPRDEL+ F IG  QCLGE   + + F+  TSI+Q F++K  +E+ E+     L   +G+IR  + +D +F
Sbjct:   27 PKGLKETPIEYGLPILG-IIHKIKEPMHNYLLKLSKKHGPIFRIKLGMRDVLILSNYDIIKKALVDDGQNFSGRWRMKLISLITHDSGIIFKDGQDWSTQRSFVLKVLRDFGLGKSKSVDLVQNECSFLLEELESLEGKIIDFSKIIPIYTANIISKFIMNKRFERENPKIARIEKMLSEEIKKKDIIQLLHIMFPKCDTSGLFCELIINFTSKWKEFLEIQN-YFKEEIDEHLKTIDFNSEGEDLMDRFLIKQNQLKQQNIDVGSFNDWQLIRSSLELFYAGYETTSTTLCWSFLFMSKHQDIQQKVHNEIIEIIGKERLPTMNDKKSMNYTQAVMDEIFRMSSVAPLALIHRTLNDANIDGYFIPKNTLIFPNLYACHFDRDIWEKPMIFYPEHFLTEDDNGNLKYTPRDELILFSIGKRQCLGESLARMEFFIFFTSILQRFRVKLVKELNEKEYEEALLGKDGIIRGSIVNDFIF 503          

Query:   68 RFYLDQTPPIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIR 1498
            R +  ++ P G ++ P    W  +G +I   + P+ ++L   S+ HGPIF++ +G R+VV+L +  TI K   +     S RW   L      +  I+FKD   W+ +RS ILKVL++F   +    +IV  ECL LL ++  + G+ I+  ++      NI+SK I+N RF+R     K +   I + S+  +++ +  L+FP  +K     +F  W +   + +      F + IEEHK   D  ++ ++LID FL EQN L ++  I++  +D QLI    E+F   +E   T L WSM+ M+R+ +IQ++++EEI+ +IG +++P + +K+SL YTQAV+DEI R SS+ P+ + H+   D  +  Y I KNSLVF N+YA H D D+W KP +FYPEHFL    N ++KY+PR+EL+PFGIG  QC+GE   + + F+   SI+Q +++ F   I++      L    G+IR
Sbjct:   19 RVFKRRSIPNGLKETPIEYGWPILG-IIPKIKGPMQNYLLELSRKHGPIFRIRLGMRDVVILGNYQTIRKALVDDAQIFSGRWKMKLVSVVTHDSGIVFKDGPVWSTQRSFILKVLRDFGMGKSISQDIVQGECLFLLNELDSLQGEIIDFSKIIPIYTANIISKFIMNKRFDRSDPRIKFIEYAIFQTSKQSDIVQRLHLMFPIFDKSTIISKFNLWITSKLQLFSKVERVFHDEIEEHKTNLDYNSEGDDLIDRFLLEQNRLSQSTGIVESFTDKQLIFMTFEMFGAGYETTSTTLGWSMLFMSRYKDIQKKVYEEILNVIGEERMPTMNDKKSLNYTQAVMDEILRLSSVAPLGIFHRTFNDTSVDNYFIPKNSLVFANYYACHTDPDIWLKPVEFYPEHFLIKCENDELKYSPREELIPFGIGKRQCIGESLARMEYFIFFVSILQRYQVDFSENISDSLFEETLRGNEGIIR 494          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML-LFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFL-KEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDV 1519
            P G R LP       IGNL  +  +  +  +   SK +GP+F + MG R++VVLS  +T+ +   NK    + R    L E       ++F D   W + R   L  L++F   ++ + + V EE   L   I+   GK +    +   ++ N++  I++  R++ E   +K L  ++ EN +I      +M  +FP L  L K  +F      + +N K  N+F K    EH +  D  N   + ID FL ++Q   G  N      +  +++RN   LFI   E   T L W  +LM ++ EIQ+++ EEI Q+IG +  P + ++  +PYT AV+ EI R+++++P+ LPH+ T D+ L  Y I K + +     +V RD   WEKPD FYPEHFL    N + K+  +D  MPF  G   C GE   K +LF+  TS++Q F   FR       S+  L  + G+  +P+  +V
Sbjct:   25 PPGPRPLP------IIGNLHIIDLKRPYRTMLELSKKYGPVFSIQMGLRKIVVLSGYDTVKEALVNKAGAFAGRPKIPLLEDIGKGKGVIFSDGENWKVMRRFTLTTLRDFGMGKKAIEDRVVEEYKCLADIIEAQKGKPLEMTLMMNAAIANVIVSILLGKRYDYEDPTFKRLLSLVNENIRIFGTPSVSMYNIFPLLGFLLKDHKF------FIQNVKEINAFIKVTFIEHLKALDR-NDQRSFIDTFLVRQQEENGNANGYFHNENLIEVVRN---LFIAGMETTSTTLRWGFLLMMKYPEIQKKVQEEIEQVIGSNP-PRIEHRTQMPYTDAVVHEIQRFANILPLNLPHETTADVTLKGYFIPKGTYIVPLLASVLRDKSQWEKPDVFYPEHFL----NSEGKFVKKDAFMPFSAGQRSCAGETLAKMELFLFFTSLLQRF--TFRPPPGVSISDLDLSPSIGLTIAPVTHEV 479          

Query:   83 QTPPIGYRKLPEGK-EWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML-LFPWL-EKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKI 1429
            Q+P  G  KLP G   +  IGN+++L ++ L  H+   S+ +GPIF + +G   VVVL     + +     G   S R    LFET      I F +   W   R  +L  LK+F   ++ + E + EE   L++ +++  G+ +N + L      NI+  I+   RF+ E KN+  L  +I ENS+++      +   FP L + +P     +F      +N++    F +E +  HK   D      + IDAFL +     +N+  +   ++  L+R+ ++LF+       T L + ++++ +  EI+ ++HEEI  +IGR + P++ ++  +PYT AV+ EI R+ ++VP+ +PH +T+D+ L +Y+I K++ +F    +V  D   +  P+ F P HFL    NG  K +  D  MPF  G   CLGE   + +LF+ LT+I+QNF +
Sbjct:   81 QSP--GSGKLPPGPVAFPLIGNMLQLRKKSLPLHIEELSRTYGPIFTIYLGSERVVVLHGYEIVKEALVGLGDEFSRRGRMPLFETATKGSGIAFTNGEQWKQLRRFVLMTLKDFGMGKKSIEERIQEETRFLVERLRNTHGRPLNPRLLLTHVFSNIICSIVFGDRFDYEDKNFVTLISLILENSKLQQSPWAALYNFFPTLMDYIPGPHHGVF------KNFEECRIFVQERVNMHKESLDPTCP-RDFIDAFLIKMEEEQKNSDSV--FTEESLVRSTVDLFVTGTGTSSTTLYFGLLVLLKFPEIEAKVHEEIDSVIGRSRSPSMADRSQMPYTDAVLHEIQRFLAIVPLGIPHAVTKDVHLKQYVIPKHTTIFAALKSVLYDSREFPNPEQFNPGHFLD--ENGAFKKS--DFFMPFSTGKRMCLGESLARMELFLALTAILQNFTL 517          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQI-KNMLIKTMLLFPWLEKLPKFVRFLFWCSEYK---RNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFL-KEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDV 1519
            P G R LP       IGNL  +  +  +  +   SK +GP+F + MG R++VVLS  +T+ +   N+    + R    +FE       ++F D   W + R   L  L++F   ++ + + V EE   L   I+   GK +    +   ++ N++  I++  R++ E   +K L  ++  N +I  +  +    +FP L          F   ++K   RN +  N+F K    EH +  D  N   + IDAFL K+Q   G+ N      +  +++RN   LF+   E   T L W ++LM ++ EIQ+++ EEI ++IG + +P   ++  +PYT AV+ EI R++++VP  LPH+ T D+ L  Y I K + +     +V RD   WEKPD FYPEHFL    + + K+  +D  MPF  G   C GE   K +LF+  TS++Q F   F        S+  L  + G+  SP+  +V
Sbjct:   34 PPGPRPLP------IIGNLHMMDLKRPYLTMLELSKTYGPVFSIQMGLRKMVVLSGYDTVKEALVNQADAFAGRPKIQIFEETGKGKGVIFSDGENWKVMRRFTLTTLRDFGMGKKAIEDRVVEEYGCLADTIESQKGKPLEMTLMMNAAVANVIVSILLGKRYDYEDPTFKKLLSLVNINVRIFGSTSVSIYNMFPVLG---------FLLKDHKIFIRNVEEVNAFIKVTFIEHLKALDR-NDQRSFIDAFLVKQQEENGKANGYFHNENLTEVVRN---LFVAGMETTSTTLRWGLLLMMKYPEIQKKVQEEIERVIGSN-LPRTEHRTQMPYTDAVVHEIQRFANIVPSNLPHETTADVTLKGYFIPKGTYIIPLLTSVLRDKSQWEKPDIFYPEHFL----DSEGKFVKKDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRF--TFHPPPGVSISDLDLSPSAGITASPVTYEV 488          

Query:  113 PEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKA-WWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML-LFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKE---QNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 1534
            P  K   ++GN+++LF+EP+   L    + +G +  L +G + ++VL+    + + F N G   S R    L E     + I+       W  +R   L  L++F   ++ + E V EE   L++++    GK          S+ NI+  I+   RF+ E K +  L +++ E   +   +I  +  L P+++  P   + +       RN      F +EI+EEH++  D  N + + IDA+L E   Q  + E+        +  +I +  +LF+   +   T L W ++ M  H ++QER H EI++++G D+ P + ++  LPYT A I EI R S+++PI  PH+ T+  +LH Y I   + +  N  A+  D + W+ PD F PE+FL    +   ++   D  +PF +G   CLGE   + +LF+  TS++Q  K  +       N N I+    G++R P   + +   R
Sbjct:   41 PGPKSLPYVGNVMQLFKEPM--DLIRSMENYGEMSCLFLGRKPMIVLNKMEIVKEAFVNNGSVFSGRPQVPLLEWVTNGLGIVMAPYGNSWKQQRRFALHTLRDFGLGKKSVEERVAEEARYLVEEMLKHEGKAFFPIHPIMNSVSNIICSIVFGDRFDYEDKRFAHLLKLLNEYVGLPGSMIGQIFNLAPFIKHFPGPHQKVL------RNANSLKGFIREIVEEHRKTLDPEN-LRDFIDAYLVEMTKQKAMEEST-----FHEENMIISTTDLFLAGTDTTATTLRWGLIYMMDHPDVQERCHNEIVRVLGFDRSPCMDDRAQLPYTHATIHEILRCSNIIPIGPPHETTQSTQLHGYHIPAGTQILANSTAIMTDRNHWKHPDVFNPENFL----DEKGQFCKNDFFLPFSMGQRVCLGESLARTELFIFFTSLIQRLKFSWPPGEPRPNMNGIM----GLVRCPFPYNTICSSR 497          

Query:  104 RKLPEG-KEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKA-WWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML-LFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFL--------KEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 1534
            R+ P G K   F+GNL++L ++P+   L    + +G +  L +G R +++L+    + + F + G   S R    + +     + I+       W  +R   L  L++F   ++ + E V EE   L++++    GK          S+ NI+  I+   RF+ E K +  L ++I EN  +   ++  +  L P+++  P   + ++      RN      F +E++EEH++  D  N + + IDA+L        KE++   E N II   SD         LF+   +   T L W ++ +  H ++QER HEEI+Q++G D+ P + ++  LPYT A + EI R S++ P    H+ T+  +LH Y I   + V  NF A+  D + W+ PD F PE+FL    +   ++   D  +PF +G   CLGE   + +LF+  TS++Q  K  +       N + +L    GMIRSP   + +   R
Sbjct:   37 RRFPPGPKPLPFVGNLMQLLKDPM--ALVRSMETYGEMSCLYLGGRPIIMLNKMEIVKQAFVHNGSVFSGRPHVPIMDWITEGLGIVMAPYGNAWKQQRRFALHTLRDFGLGKKSVEERVAEEARYLVEEMLKHEGKAFFPIHPIMNSVSNIICSIVFGDRFDYEDKRFAHLLKLINENIWLAGSIVAQVFNLVPFIKHFPGPHQKIW------RNACSLKGFIREVVEEHRKTLDPEN-LRDFIDAYLVEMTKQEAKEESTFHEENMIIS-TSD---------LFLAGTDTTATTLRWGLIYIMDHPDVQERCHEEIVQVLGFDRSPCMDDRAQLPYTHATVQEILRCSNISPFGGVHETTQPTQLHGYHIPAGTQVLANFTAIMSDRNHWKHPDVFNPENFL----DEKGQFCKNDFFLPFSMGPRVCLGESLARTELFIFFTSLIQRLKFSWPPGEPRPNMDGVL----GMIRSPFPYNTICSSR 497          

Query:  110 LPEG-KEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDK--AWWTIRRSLILKVLKNFISK-----------EQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML--LFPWLEKLP-----KFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            LP G + W  +GNL ++  E L   L +   ++G +F++ MG  EVVVLS  +TI +    +G   + R     F   +   ++ F +K    WT+ + +    L+ F              E+++ E V E   +L +  + V  + ++   L   S+ N+   +    R+   S N +    I+  N+++  +     L   FP    LP     K V+++             N F ++ I+EH   FD  N + ++ DA ++   +  E+ R    ++D Q+I   I++F   F+ I T L WS++ + +   I+ RI +EI   +G +++P   +K  +PYT+A + E+FR++S +P TLPH  TE+I L+ Y I K++ VF+N Y V+ D ++W  PD F PE FL    +  I     ++++ FG+G  +C+G++F + ++F+ LT+++Q   I+
Sbjct:   42 LPPGPRAWPVVGNLFQM-GEQLHLSLTHLGAVYGDVFRVKMGSLEVVVLSGLSTIRQALVRQGEAFAGRPELFTFTAVSDGNSMTFSEKYGEAWTLHKKICKNALRTFSQAKARNSSSSCLLEERITEEVLEMVEVLREQGEKVGDEGLDPTALLAISVANVACALCFGKRY---SHNDEQFLTIVNINNEVLKIFASGNLADFFPVFRYLPSPSLRKVVQYIHR----------MNCFMEDHIKEHLLSFDK-NCIRDITDALIELCEDRQED-RDKAMLTDSQIIHTVIDIFGAGFDTIITGLQWSLLYLIKFPHIRTRICQEIDDQVGLNRLPTFEDKAKMPYTEAFLYEVFRHASYMPFTLPHCTTENITLNGYFIPKDTCVFINQYQVNHDPEIWSDPDSFQPERFLS--PSSQINKDVVEKVLIFGMGKRRCVGDRFARLEMFMFLTTVLQRLHIE 485          

Query:  194 SKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQI---KNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEE 1456
            +K +G +FK+  G ++VVVL+   T+ +   N      ER    +F+ YN E  ILF +   W   R   L  L++F   ++   E + EE   L +  +   GK  +T +    ++ NI+S I+   RFE     +K +     EN +I    ++L+  M  FPW  +  + V+ LF  +E  R   +Q    +E+++  +   ++  +    +D+FL  +  + E+N      ++  LI     LF+   +   T L W ++LMA++  IQ+R+HEEI ++IG  ++  + +++SLPYT AVI EI R +++VP++LPH  + D+  + + I+K + V+    +V RD   WE P  F P+HFL    +   ++  +D  MPF  G   CLGE   + +LF+  TS++Q+F+      +TE+
Sbjct:   70 AKTYGSVFKVYFGPKKVVVLAGYKTVKQALVNHAEEFGEREVSPMFKKYNEEHGILFSNGENWREMRRFALSNLRDFGMGKRGSEEKIIEEIQYLKEVFESFGGKAFDTTQPVNNAVSNIISSIVYGSRFEYSDPQFKEMVNRANENVRIGGSASVLVYNM--FPWTGRFLRSVQKLFVNNEKNR---VQ---IRELVKGLQETLNTEER-RGFVDSFLLRK-QIDESNEKASYFNEKNLIVTVGNLFVAGTDTSGTTLRWGLLLMAKNPHIQDRVHEEIDRVIGGRQVV-VEDRKSLPYTDAVIHEIQRCANIVPMSLPHVTSCDVHFNGFFIKKGTTVYPLLTSVLRDESEWESPRTFNPDHFL----DKQGQFLKKDAFMPFSAGRRVCLGESLARMELFLFFTSLLQHFRFTPPPGLTED 478          

Query:  104 RKLPEG-KEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSER--WPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML-LFPWLEKLPKFVRFLFWCSEYKRNYKIQNS---FFKEIIEEHKRKFDSMNKVENLIDAFLKE---QNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 1534
            R+ P G K   F+GN ++L ++P+   L    + +G +  L +G R ++VL+    + + F + G   S R   P + + T    + ++    AW   RR   L  L++F   ++ + E V EE   L++++    GK          S+ NI+  I+   R++ E K +  L +++ EN ++    +  +  L P+++  P           +++ +K  NS   F ++I+EEH+   D  N + + IDA+L E   Q  + E+        +  +I +  +LF+   +   T L W ++ M  H ++QER HEEI++++G D+ P++ ++  LPYT A + EI R S++VP+ + H+ T+  +LH Y I   + V  NF A+  + + W+ PD F PE+FL    +   ++   +  +PF +G   CLGE   + +LF+  TS++Q  K  + +     N + ++    G++RSP   + +   R
Sbjct:   37 RRFPPGPKPLPFVGNTMQLLKDPM--DLIRSMENYGEMSCLFLGGRPIIVLNKMEIVKEAFVHNGAVFSGRPHMPVLDWITDGLGIIMVSYGNAWKQQRR-FALHTLRDFGLGKKSVEERVTEEARYLVEEMLKHEGKAFFPIHPIMNSVSNIICSIVFGDRYDYEDKRFAHLLKLVTENVRLTGSFVGQVFNLVPFIKHFP---------GPHQKIWKNANSLKCFIRDIVEEHRNTLDPEN-LRDFIDAYLVEMTKQEAIEEST-----FHEENMIMSTADLFLAGTDTTATTLRWGIIYMMDHPDVQERCHEEIVRVLGFDRSPSMDDRAQLPYTHATLHEIMRRSNIVPLGVGHETTQPTQLHGYHIPAGTQVVANFTAIMSERNHWKYPDVFNPENFL----DEKGQFCKNEFFLPFSMGPRVCLGETLARTELFIFFTSLIQRLKFSWPKGEPRPNMDGVM----GIVRSPFPYNTICSSR 497          

Query:  113 PEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILF-ETYNCEMNILFKDKA-WWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML-LFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNG 1489
            P  K   F+GN + LF++P  + L   +K +G +  +++G   +V +S    + +V  ++G   ++R P+  F +  N  + I+F     +W   R   L  L+NF   +  + + +  E   L++  K   G   +       ++ NI+  ++   R+E   K ++    ++E N Q+++ L+ T+  +FP+L   P   + +F      ++      F ++II E     D + K   LIDA+L +   L + +      S+  LI   ++LFI   E   T L W ++ M  H EIQ + HEEI +++G D++P + ++ SLPY  AVI EI R+S++VP   PH  T D++  +YLI K +++ VN  +V  D + W+ P +F PE+FL    + D K+   D  +PF  G   CLGE   K +LF+   S++Q+F+  +   ++      IL  T  
Sbjct:   55 PGPKVIPFLGN-VSLFKKPDVA-LDEVTKQYGEVCSVMVGKISMVFVSGYQAVKEVLVHQGHEFADR-PNTPFNKKVNGGLGIIFAPYGKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGFLIEAFKQK-GSAFDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVENNLQLQSGLLGTLCNIFPFLMDFPGPQQIIF------KSMAKSKQFIRDIISERHATRDPI-KPMCLIDAYLSQ---LEKEDNPNSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGSDRLPCMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFL----DEDGKFVKPDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFEFYWPDLVSAPTLGYILQITKA 498          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDI-LFETYNCEMNILFKDKAW-WTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIK-NMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVE----NLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPF-GIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            P G R LP       +GNL +L  + L + L   S+ +GPI+ + +G   VVVL  N  I +    +     +R P+I +F+        L     W W  RR   L +L+NF    + + E + EE   L++ I++   K  +      KS  N++  I    R++  +K +  L +II EN ++  N   +    FP L+  P   +         +N  + N+F +  IEEH      M +++    + +DAF+ ++  + ++       SD  LI     LF+   E     L W ++LM  + ++QE++ EEI +++G ++ P   ++  +PYT A + EI RY++++P+  PH  T D +L  Y + K + V    ++  R+  +WE P+ F P HFL +    D  +  R++ M F  +G   CLG+   + ++F+  T+++Q F  +
Sbjct:   41 PPGPRGLP------LVGNLFQLDLKALPASLDKLSETYGPIYSVSLGQTRVVVLVGNEIIKEALVTQAEMFIDR-PEIPVFKKSLGNYEGLLLSHGWQWRARRRFTLMMLRNFGMGTKSIEEKIAEEAEFLVRAIENKQEKPFDAHSEINKSAANVICSITFGDRYDWNNKTFVKLMDIITENVELSGNDWSQIFNSFPVLKYFPGPHQ------RINKNKVVLNAFIQARIEEH-----DMARIQGEPRDYLDAFIDKR--IEDSMNPDTAFSDIALINTTANLFVAGSETTSATLKWGILLMLTYPKVQEQVQEEIDRVVGSNRRPACADRACMPYTNATVHEIQRYANILPMAFPHATTCDTKLRGYFLPKGTQVIALIHSALREKSLWEAPEQFNPGHFLDI----DGNFYNRNDFMAFSAVGPRICLGKNLARMEVFLFFTALLQRFSFQ 471          

Query:   98 GYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDK--AWWTIRRSLILKVLKNFISKEQK-------LIEIVNEECLILLKDIKDVCGKE--INTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEH-KRKFDSMNK--VENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            G R LP    W  +GN+++L+ +P    L      +G +F++ +G   VVVLS   TI +     G   + R P            + F       W   + L    L+NF +   +       L E V EE   LL   K    +    +       ++ N++  ++   R+      +  +    EE SQ+       +  FP+L  +P         +   R  K+ ++     +E H K  + S  K  V ++ DA +          R + G+SD +++   +++F   F+ I T L+W ++ +  H ++Q ++  EI + IGRD+ P   ++ +L   +A + E+FR+S+ VP T+PH  T+D+ L+   I +++ VFVN + V+ D  VW  P+ F P+ FL      ++     +++  FG+G  +CLG+   + +LFV+L +++Q    +
Sbjct:   54 GARPLPGPVRWPIVGNILQLWPDPHLK-LTRMCDRYGDVFRVHLGSVPVVVLSGLETIKRALVKNGDAFAGRPPFYSLSLVGNGDTLTFTRAYDGCWKAHKRLARSALRNFCAAPARREGYACLLEECVCEEAERLLLACKGGGAQPGGFDPVPSITCAVANVMCALVFGKRYPHGDPTFLQIVGFNEEASQLSGA-GNLVDFFPFLRHVP---------NAQLRALKVLSARLLAFMEGHIKEHYSSYQKGHVRDITDALIAMCAEQEHALREV-GLSDERVVATALDIFGAGFDTIITGLTWCLLYLCIHPDVQHKLQREIDETIGRDRTPRFEDRANLRRVEAFLTEMFRHSAFVPFTIPHSTTQDVVLNGMFIPRDTCVFVNLHQVNHDPTVWSDPERFDPDRFLS-HDGKEVNKEMVEKVQIFGLGKRRCLGDMVARQELFVVLVTLLQGLSFR 499          

Query:  194 SKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKA-WWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIK-NMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFK 1426
            +K +G +  +++G   VV++S    + +V  N+G   ++R    +F      + I        W  +R   L  L+NF   +  + + ++ E   L++  K       +       ++ NI+  ++   R++ +++ ++ L  ++E   Q++   L+    +FP+L KLP       W   +  + K+Q     +I+ EH+   D  N   +LID++L + +   +N       +   LI+  IELFI   E     L W ++ M  + +IQ R H EI +++G ++ P + ++RSLPY  AVI EI R+ +++P+ + H  ++D++ ++YL  K + V VN  +   D   W+ P+ F P+HFL    + D +    D  +PF  G   CLGE   K ++F+  TS++Q+F+
Sbjct:   67 AKKYGEVCTIMLGSTPVVLVSGYEAVKEVLVNRGHEFADRPITPIFTKLTQNIGIALAPYGDPWKQQRRFALSTLRNFGFGKATIADKISIEAKYLIETFKQETSA-FDPHLNLNNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILCNVFPFLLKLPGP-----WQKVFHIHSKLQ-CLLNDIVSEHRATKDQHNP-RDLIDSYLAQIDKEKDNPN--SSFTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSERPPCMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFL----DKDGQCIQSDAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHFE 465          

Query:  539 SMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLF-PWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMV-LMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPL 1507
            ++ NI+  I+   RF+ + K ++ L  +  EN +I+      + +F PWLE  P   + +F      RN    N FF+E I EH++  ++  +  +LIDA+L E     E+       +D  L+    +LFI   E   T L W+++ +MA      ER   EI ++IG D+ PN  ++ +LPYT AVI E  R +++ P+ + H  T D++   Y I K + V +N  +V  D   W+ P++F P+HFL    +   ++   D  + F  G   CLGE   + +LF+  TS++Q FK  +    +  N         G+ R+P+
Sbjct:   13 AVSNIICSIVFGNRFDYDDKRFRNLLHLFAENFRIEGGWRGKICIFMPWLEDWPGPHQLIF------RNADKVNLFFQERIREHRQTREA-GQPRDLIDAYLDEMEK--ESQDPESTFTDGNLLNVVGDLFIAGTETSSTTLRWALLYMMAYPQIQAERCQREIDEVIGGDRSPNTTDRANLPYTDAVIHEAQRMANVAPLGVLHSTTTDVKFRGYNIPKGTKVLLNLTSVLHDETQWKTPNEFNPDHFL----DNTGQFVKPDAFLAFSAGPRVCLGENLARMELFLFFTSLLQRFKFHWPDATSRPN----FVAAEGLSRAPV 320          

Query: 1082 YTQAVIDEIFRYSSLVPITLPHKITEDIELHE-YLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVIL 1402
            YT  VI E  RY   V + +P+ + ++  +   Y   K +++    Y    D +V+E PD+F PE +++    G      +   + FG G   CLG+ +       +L
Sbjct:  388 YTNMVIKETLRYRPPV-LMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVE----GSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALL 490          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVN-------------LSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDG-ISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKY-TPRDE-LMPFGIGSMQCLGEKFTKFQLFVILTSIVQNF 1423
            P G   LP       IGNL+ +    +   L N +K HG I  + +   ++VV++S     +V   K +N             +S+ + DI    Y+  +        W   +R ++   L+ +      L + + +E   L   +    G  +++K+ F   ++NI+   +    F++E   +    E++ +     +M    +  FP+L   P     L     +KR  ++++     I+  HK  F+  N + +L DAFLK + ++   ++   G ++D ++    +++++   E   T L W +  +  + E+Q R+   I  +IG D+ P + +++ LPY +A++ E+ R S  +P+ LPHK   D  +  Y I K + V  N +A+H D   W +PD F P+ F+    N D K+  P D   +PF  G   CLGE   K +LF+I+T ++Q F
Sbjct:    2 PPGPTPLP------LIGNLLSIKSSNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGL-------VW---KRKIVHSGLRKYFPS---LGDTIAKELAKLEDKLNSDVGVPVDSKDEFFLLVLNIICSFLSGKAFDKEDPEFSETLELVTKTVDTLSMSASILDAFPFLIHFP-----LQASKNFKRIAELRDKLMGNILTFHKETFNE-NHIRDLTDAFLKAKLDIEREDKKAAGEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIG-DRRPLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFI----NEDGKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQF 431          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLS-------------ERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWL-EKLPKFVRFLFWCSEYKRNYKIQNSFF---KEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRII-DGISDWQLIRNG-IELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFK 1426
            P G R LP       IGNL  L    +        K +G IF++ +  + ++VLS  + I +    +  N +             +RW   LF     E          W I R L    +K  +  E +L E++NEE   L K +++   K I+  + F  ++ N++   I   R++     ++ L  I ++++++        +   WL E  P    FL +  + K   ++    F   +   +EH   FD  N + +  DA LK +    E ++   +   +  +I  G + LF+   E   T LSW++  +  +  +Q R+H+EI Q+IG+D  P L  ++++P  +A   E  R S+LVP++LPHK T D  L  Y I K + VF N +++H D  +W++PD F  + FL     G  +       +PFG G   CLGE   + +LF+ L +++Q+F+
Sbjct:    1 PPGPRPLP------LIGNL-NLLSNQMHLDFAALEKTYGKIFRVYLAHKPIIVLS-GDAIKEALVRQPRNFAGRPLLPITEEIVDKRWGPALFAMDYGER---------WRIFRKLGHSTIK--VYGEDRLQEVINEEVSELCKRLEESDEKPIDITKQFGTAVTNVICTKIFGNRYDINDPEFQRLYYINDKSTRLN-------IGEGWLKEAFPFLKPFLPYSQQVKEIKELDQERFVIMRAKYDEHVETFDP-NHIRDYTDALLKAKQEAEEEDKSSKEHFGEGPIIMAGLVTLFLAGSETTTTTLSWAIAYLLHNPGVQARLHKEIDQVIGKDVSPKLSQRKNIPVLEAFTAETQRLSNLVPLSLPHKTTSDCTLLGYEIAKGTTVFTNLWSLHHDPSIWKEPDTFNLDRFLD--AKGKFQAPVGGTFLPFGAGPRVCLGEVLARSELFLFLATLLQHFE 435          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVN-------------LSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLG-ENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKY-TPRDE-LMPFGIGSMQCLGEKFTKFQLFVILTSIVQNF 1423
            P G   LP       IGNL+ +    +   L N +K HG I  + +   ++VV++S     +V   K +N             +S+ + DI    Y+  +        W   +R ++   L+ +      L + + +E   L   +    G  +++K+ F   ++NI+   +    F++E   +    E +       +M    +  FP+L   P     L     +KR  ++++     I+  HK  F+  N + +L DAFLK + ++  E+ +  + ++D ++    +++++   E   T L W +  +  + E+Q R+   I  +IG D+ P + +++ LPY +A++ E+ R S  +P+ LPHK   D  +  Y I K + V  N +A+H D   W +PD F P+ F+    N D K+  P D   +PF  G   CLGE   K +LF+I+T ++Q F
Sbjct:    2 PPGPTPLP------LIGNLLSIKSSNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGL-------VW---KRKIVHSGLRKYFPS---LGDTIAKELAKLEDKLNSDVGVPVDSKDEFFLLVLNIICSFLTGKAFDKEDPEFSETLEFVTMTVDTISMSASILDAFPFLIHFP-----LQASKNFKRIAELRDKLMGNILTFHKETFNE-NHIRDLTDAFLKAKLDIEREDKKAAEEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIG-DRRPLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFI----NEDGKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQF 431          

Query:  194 SKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMN---ILFKD-KAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML-LFPWLEKLP-KFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFL----KLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFK 1426
            +K +G +F+L +G   +VV++S     +    +  + + R   +L+       N   I F D    W  +R +    L+ F S  + L E +  E   L+K +  V G+  N K+    +++NI+   +   R++ +   +  + +  E+   ++     +++  FPWL  LP K +R      + K   + ++   ++  +EH   ++    + +L DA L       E +  +    D  +I    ++F    E   T + WS+V + R+ ++QE++H++I +++GRD+ P L ++ +LP  +A I E+ R SSLVP+  PH  T D  L  Y + K+++V  N + +H D   W  PD+F P  FL    K +    + Y      +PF  G   CL E   K QLF+ ++ ++  F+
Sbjct:   16 AKSYGEVFRLKVGSHRIVVVNSIEAAREALVRRANDFAGR--PMLYTASLISRNGTDIAFGDFGPLWKQQRKIAHSALRMFGSGLKPLEEKITVEADELIKRLSLVEGRAHNPKDDVNLAVLNIICSFVFGSRYDMDDPEFHTVVDYTEQF--VQGFRAASLVDYFPWLRHLPNKGLR------QIKEACQNRDVVLQKKYQEHLVTYEH-GVIRDLTDALLSANKASQEESAYLPMTED-HIIMTMNDIFSAGLETTATSILWSLVYLIRNPKVQEQLHQQIDEVVGRDRAPELSDRENLPLIEATIAEVLRSSSLVPLLFPHSTTTDTHLRGYEVPKDTIVLFNVWNMHHDPQRWSNPDEFDPTRFLDDKGKFICPATLSY------LPFSAGRRVCLAESLGKMQLFLFISRLLHKFR 418          

Query:  101 YRKLPEG---KEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWP--DILFETYNCEMNILFKD-KAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEE---NSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRN---YKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDG--ISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSP 1504
            +R +P G   K   F+GNL  +  E   S L    + +G +F   +G  +VV   +   I ++  +K  + + R P    L ET   + +I F +  + W + R L    L+ ++S    L   V E+   LLK ++    +  +  ++   S+ +++  I     F    K++K   ++  +   ++++ N L    L +        F R+ F  S YK N   +       + ++EE K  +D+  +V+NL+   LK ++     N       +SD  LI +  ++    +E     L WS+V +  + ++Q  I  E+ +++G +++P++ ++  LPYTQAVI E  R  ++   ++PH    D  L  Y I K+++V V+  A+HR    W+ P  F P   L    NG++  T +   +PF  G   C GE   K +LF+ L+ ++Q F   F  E  E  +  I+    G  ++P
Sbjct:   38 FRGMPPGPRLKYLPFVGNLFDILYED--SSLKGLKQKYGEVFSFQVGSWKVVQAGTPEAIKEILISKSADYAGRPPFYSFLVETLGGK-DIAFGNYGSAWKLHRKLFSTCLRQYVSNVPLLESCVGEQAKKLLKFLEYQKEQPFDPSDILMTSIADVICGITFGKYFGSWHKDFKTFLKLTNKSFGDTELNNQLFLLDLFY--------FTRY-FPFSAYKENQADFDTVLGIIRRVLEEGKAHYDT-KQVDNLMMGLLKARSEAEHENEEEKKALLSDDYLIGSLYDMMAAGYETTAATLKWSIVYLVNYPDVQTTIQAELTKVVGPNRMPSINDRPHLPYTQAVIMETLRLGNVADQSIPHYTLCDTTLTGYRIPKDTVVNVDLEALHRHPVCWDNPTLFEPRRHLD--ANGEL-VTSQGNWLPFSAGRRVCSGEALAKAELFLFLSWMLQKF--HFVPEEGEGQTPPIIKAVKGFTQNP 501          

Query:   83 QTPPIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNM-LIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNF 1423
            Q PP G R LP       IGNL+++  +  +  L   SK +GP+F +  G  +VVVL+   T+     N      ER    + +  N  + +L+ +   W   R   L  L++F   ++   + + EEC  LL+  K   G   +T +    ++ NI+  ++   RFE +   +  + +    N Q+     ++   + PWL K     R +  C+   R    QN    + I  H ++  +       +DAFL +   L ++       +D  L+   I LF    E   T L W ++LMA++ +IQ+++ +E+ ++IG D++  + ++++LP+T AVI EI R +S+VP  LPHK ++D+    Y I+K + VF    +V  D + WEKP  FYP HFL    + D K+  R+  +PF  G   CLGE   + +LF+  T+++QNF
Sbjct:   39 QEPP-GPRPLP------IIGNLMQIDLKRPYKTLEEFSKTYGPVFTVFFGGEKVVVLAGYKTVKNALVNHDEEFGERAIPPIIQELNKGLGVLWSNGDIWRDIRRFALTNLRDFGMGKKACEDKITEECQYLLEVFKKFKGNAFDTTKPLNYAVSNIICSMVYGSRFEYDDPKFTSMVDRTNRNIQLSGSPTLQAYNMVPWLFKWVASRREVHECAAANRK---QN----QSIFSHLKETLNPQMCRGFVDAFLVKGQTLEKSGVTNSAFNDENLLMTVIHLFAAGTETTSTTLRWGLLLMAKYPKIQDQVQDELRRVIG-DRMVQVSDRKNLPFTDAVIHEIQRLASIVPTALPHKTSKDVTFQGYFIKKGTTVFPLLTSVLHDANEWEKPHTFYPAHFL----DKDGKFVKREAFIPFSAGRRICLGESLARMELFMFFTTLLQNF 467          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNK--SKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYK-ILNEIIEENSQIKNMLIKTMLLFPWL-EKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKE-QNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSP 1504
            P G R LP      FIG+L R+   P   HL  K  +  +G +F L +   + VVL+    + +    KG +  +R    LF        I+  +   W  +R   L  L+NF   ++ + + + EEC  + +   +  GK  + + L   ++ NI+  ++   RFE   K Y+ IL ++ E      +       +FPWL ++ P  ++ LF   +     KI + F K  IEEHK   D     ++ ID+FL E + N GE+     G     L    ++LF    E   T L W ++ M  + +IQE +H EI  +IG  + P++ +K ++PYT AVI EI R   +VPI +    + D  L  Y I K +++    + V  D  VWE P  F P+HFL    N D  +  R+   PFG G   CLGE+  + +LF+  TS +Q F        T       L    G IRSP
Sbjct:   41 PPGPRSLP------FIGDLHRI--RPTILHLQFKEFAAKYGNVFSLNIFGGKTVVLNGTKLLKEALIQKGDDFVDRPQIPLFSDLIENKGIVMTNGIQWKHQRRFALHTLRNFGLGKKTMEKYIQEECHYITQAFAEHQGKPFDAQPLLNSAVSNIICCLVFGERFEYSDKEYQQILQDLTEVVKLQGSFSALAYNVFPWLMKRFPGPLQKLFTLVD-----KIMD-FVKIKIEEHKENLDPACP-KDYIDSFLIEMEKNQGEDF----GFDIKNLCACTLDLFGAGSETTTTTLYWGLLFMIHYPDIQEEVHAEIDAVIGSSRQPSMADKENMPYTDAVIHEIQRMGDIVPIGVARMASRDTMLDNYTIPKGTMIMPALHTVLHDESVWETPHSFNPQHFL----NQDGTFKKREAFFPFGAGKRVCLGEQLARMELFLFFTSFLQRFSFS-----TAGGEKPPLEGRMGTIRSP 488          

Query:  137 IGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNY----KILNEIIEENSQIKNMLIKTMLLFPWL-EKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNF 1423
            IGNL++L ++  +  +   SK +GP+  + MG +  V L   + + +   ++  +   R P            I   +   W   R   L  L++F    + + + + EE   +   I  + GK  +   L   ++ N++  ++   RF  + K +    K+++EI+  N   K  +     LFPWL E+LP     +F   E  RN      F K+ I+EHK   D  +   + ID FL   +   E +          L+   + LF+   E   + + +++ ++ +H +IQE++ EEI  +IGR++ P++ +++SLP+T AVI E+ R+  L P +LPH   +DI    Y I K++++F   ++V R+  +W  P  F P++FL    NG+ K  P    +PF  G   C+GE   + +LFV + S++QNF
Sbjct:   40 IGNLLQLDKKRPFRTIVELSKTYGPVMTIYMGWQRAVALVGYDAVKEALVDQADDFVGRAPLPFLYRATRGYGIGISNGERWRQLRRFALTTLRDFGMGRKGMEQWIQEESRHIRAHINSLKGKPFDPTFLLSCAVSNVICCLVYGERFNYDDKQFLELLKMISEILGFNGGPKGAMYN---LFPWLMERLPGHQHTIFGYIEDIRN------FAKKKIQEHKDTLDP-SSPRDFIDCFLLRMDQ--EKDNPTSEFHYENLVSTVLNLFLAGTETTSSTIRYALSVLIKHPKIQEKMQEEIDSVIGRERCPSMEDRKSLPFTDAVIHEVQRFMDLAPFSLPHYSLKDISFRGYTIPKDTMIFPMLHSVLREDKLWSSPWSFNPQNFLD--QNGNFKKNP--GFVPFSAGKRACVGESLARMELFVFIVSLLQNF 457          

Query:  137 IGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNY----KILNEIIEENSQIKNMLIKTMLLFPWL-EKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNF 1423
            IGNL++L ++  +  +   SK +GP+  + MG +  V L   + + +   ++  +   R P            I   +   W   R   L  L++F    + + + + EE   +   I  + GK  +   L   ++ N++  ++   RF  + K +    K+++EI+  N   K  +     LFPWL E+LP     +F   E  RN      F K+ I+EHK   D  +   + ID FL   +   E +          L+   + LF+   E   + + +++ ++ +H +IQE++ EEI  +IGR++ P++  ++SLP+T AVI E+ R+  L P +LPH   +DI    Y I K++++F   ++V R+  +W  P  F P++FL    NG+ K  P    +PF  G   C+GE   + +LFV + S++QNF
Sbjct:   40 IGNLLQLDKKRPFRTIVELSKTYGPVMTIYMGWQRAVALVGYDAVKEALVDQADDFVGRAPLPFLYRATRGYGIGISNGERWRQLRRFALTTLRDFGMGRKGMEQWIQEESRHIRAHINSLKGKPFDPTFLLSCAVSNVICCLVYGERFNYDDKQFLELLKMISEILGFNGGPKGAMYN---LFPWLMERLPGHQHTIFGYIEDIRN------FAKKKIQEHKDTLDP-SSPRDFIDCFLLRMDQ--EKDNPTSEFHYENLVSTVLNLFLAGTETTSSTIRYALSVLIKHPKIQEKMQEEIDSVIGRERCPSMEERKSLPFTDAVIHEVQRFMDLTPFSLPHYSLKDISFRGYTIPKDTMIFPMLHSVLREDKLWSSPWSFNPQNFLD--QNGNFKKNP--GFVPFSAGKRACVGESLARMELFVFIVSLLQNF 457          

Query:  137 IGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDK--AWWTIRRSLILKVLKNF------------------ISKEQKLIEIVNEEC--LILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTML--LFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIK 1432
            +GNL ++  +   S    ++K HG +FKL +G   VVVLS  NTI +    +G + + R     F       ++ F +K    W + + L    L++F                   ++  +++E++ E+   + L  ++ D   K ++  +    S+ N++  +    R++   K +     I+  N+++  +     L   FP     P          E  +  +  N F +  IEEH   FD  N + ++ DA +    +  E ++ +  +SD Q+I + I++F   F+ I   L WS++ + +  ++Q RIH+EI + IG  ++PN  +K  +P+T+A I E+FR+++ VP T+PH  T    L+ Y I K++ VF+N Y V+ D D+W  P+ F P+ FL    +G +     ++++ FG+G  +CLG+ F + ++FV L +++   +I+
Sbjct:   68 VGNLFQMGNQMHLSLTLLRAK-HGDVFKLRLGSLPVVVLSGYNTIRQALVRQGEDFAGRPELFTFSAVADGTSMTFSEKFGPAWLLHKKLCKNALRSFSQAAPRGSGATCLLEEHVCAEAAEMLEMIREQSAKVELDSEMTDGASKGVDPVKPLVTSVANVVCALCFGKRYDHNDKEFLT---IVNINNEVLKLFAAGNLADFFPVFRYFPSL-----SLKELVQYIRRMNGFMERRIEEHMHTFDK-NYIRDITDALIALCEDR-EKSKEMSLLSDTQIIHSVIDIFGAGFDTIIAGLQWSLLYLIKFPDVQRRIHQEIDEHIGSARMPNFSDKSKMPFTEAFIYEVFRHAAYVPFTIPHCTTRHTTLNGYFIPKDTCVFINQYQVNHDKDLWGDPEQFCPDRFLG--HSGQLNKELTEKVLIFGMGKRRCLGDGFARLEMFVFLATLLHGLRIE 510          

Query:  227 MGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 1534
            MGCREV+VLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGI+DWQLIRNGIELFIVAFEKIRTLLSWSMVLMARHSEIQERIHEEIIQLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR
Sbjct:    1 MGCREVIVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGITDWQLIRNGIELFIVAFEKIRTLLSWSMVLMARHSEIQERIHEEIIQLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 436          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 1534
            P G + L     W  IGNL  + +EPLWS LY ++  +GP+FK  MGCR++VV+SSN  + K  K KG+  S RW +I+  T      ILF D  WW  +RS  LKVLK+F   +Q+  EI++ EC  LLK+I++ CGK I+ + LF K  VN+++K+ +N+RFER++ N+K L   +E  +Q KN ++  +L++P LE+ P+  + L   S  ++ ++  ++ F+ IIEEHK++F+  N+ E+ ID FL+E+  L     +    +DWQL+R   ELF+  +E   T L+W+M+LMA++ EIQ+++H+EI+ +IG ++IPN+ +K+SLPYTQAV+DEIFR +S+VP++LPH++ E+ E++   I KNS++F N YA HRD +VW++P +FYPEHFL   +NG IKY+P DEL+PF IG  QCLGE   + + F+  TSI+Q FK+KF +EI+ +    +   T+G IR+PL+SDVVFE+R
Sbjct:   30 PKGLKPLQGPSGWPLIGNLFTI-KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAITLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWTMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTEESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 509          

Query:   62 IRRFYLDQTPPIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 1534
            I++F+ +Q+       L     W  IGN I  F EPLW  LY  SK +G +FK  MG R++V+LSS+  + K  K +G N S R+ + L +       ILF +K WW  +RS  LKVL++F   +Q+  EIV+ EC+ILLKDI++ CGK ++ + LF K+ VN+++K+++N+RFE +SK++  L ++IE+  Q  N ++    ++P L+ +P    FL W S   +  KI + F   II++HK++F+  N+ E+ ID FLKEQ+ L E        +D QLIR  +ELF   +E   T LSWSM+L+A+H  IQE++++EI+ L+G +K+PN  +K+ L YTQAV+DEI R S++VP+++ H++ E+ E+    I K+S++F N +A HRD +VWEKP +FYPEHFL +  +G +KYTPRDEL+PF IG  QCLGE   + + F+ LT I+Q FKI+F  EI+EE    I   T+G IR+PL+SDVVFE+R
Sbjct:   18 IKKFFFNQSASKNLNLLQGPTGWPLIGN-INSFNEPLWMVLYKYSKHYGSLFKYTMGRRDIVILSSSKMLFKTLKEQGNNFSGRFQNFLIKARTRNSGILFTEKEWWATQRSFALKVLRDFGFGKQRSQEIVSNECMILLKDIEEECGKVVSARSLFPKATVNVIAKLVMNMRFESDSKDFTELTKLIEKAIQNNNFILTLFQMYPILDNMPFIAPFLLWWSGRNKTAKITSKFINNIIDDHKKRFNIENEGEDFIDIFLKEQHKLNEEKVKNHTFTDQQLIRVVLELFFAGYETTSTTLSWSMLLLAKHPNIQEKVYQEIVDLLGTEKLPNFADKKCLQYTQAVMDEILRVSTVVPLSISHRVFENTEVDGVYIPKDSIIFPNLFACHRDENVWEKPFEFYPEHFLNINNSGQLKYTPRDELVPFSIGKRQCLGEGLARIEFFIFLTGIIQKFKIRFENEISEEEFAKITRGTDGGIRAPLSSDVVFELR 507          

Query:   92 PIGYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKF-VRFLFWCSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 1534
            PIG R L     W  +GNL  + +EPLWS  Y  +K +G IFK  +G RE+V+++S+  + K  K++GVN S R  + L +    +  I+FK+K WW+ +RS  LKVL++F   +Q+ IEIVN EC ILL+++++  GK I TK  F    VNI++K+++N+RFE+ S  +    +IIE+ +  ++ L+   +LF  +  LP F + F+   S  + +    ++F   II E K+ F   N+ ++ ID FL E++ L   N      +DWQLIR  +ELF   FE   T LSW+MVL+ARH+EIQ+++H+EII LIG DKIP+L NK+ L YTQAV+DEI R S++ P+ +PH++  D E+  + I K+S +F N YA HRD  VWEKP DFYPEHFL  L NG++KYTPR+EL+PF  G  QC GE   + + FV LTSI+Q FKIKF + I +     I   T+G +R+PL+ D++FEMR
Sbjct:   30 PIGLRPLQGPSGWPLVGNLFSI-KEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLV---ILFQ-IYTLPHFTIPFIARFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 506          

Query:   71 FYLDQTPPI--GYRKLPEGKEWSFIGNLIRLFREPLWSHLYNKSKIHGPIFKLIMGCREVVVLSSNNTICKVFKNKGVNLSERWPDILFETYNCEMNILFKDKAWWTIRRSLILKVLKNFISKEQKLIEIVNEECLILLKDIKDVCGKEINTKELFRKSMVNILSKIIINLRFERESKNYKILNEIIEENSQIKNMLIKTMLLFPWLEKLPKFVRFLFW-CSEYKRNYKIQNSFFKEIIEEHKRKFDSMNKVENLIDAFLKEQNNLGENNRIIDGISDWQLIRNGIELFIVAFEKIRTLLSWSMVLMAXXXXXXXXXXXXXXXLIGRDKIPNLVNKRSLPYTQAVIDEIFRYSSLVPITLPHKITEDIELHEYLIQKNSLVFVNFYAVHRDGDVWEKPDDFYPEHFLKLLTNGDIKYTPRDELMPFGIGSMQCLGEKFTKFQLFVILTSIVQNFKIKFRREITEENSNSILHETNGMIRSPLNSDVVFEMR 1534
            +++ + PPI  G +++P       IG + ++   P+  +L    +  GPIF++ +G R++VVL++   I K   +   N S RW     +    +  I+FKD   W  +RS ILKVL++F   + K IEIV  EC   L ++  + G+ ++  EL      NI+S+ I+N RF R+  N +++ E I  +++ K+++   +L+FP  +      + ++   S++K   KIQN +F E IEEH+   D  ++ E+L+D FL +Q+ L ++   ++   DWQLIR  +ELFI  +E   T L+W  + M+++ +IQE++H+EI ++IG++++P + +K++L YTQAV+DE+ R SS+ P+ L H+  +D  ++ + I K+SL+F N YA H D ++WE P  FYPEHFL L +NG  KY PR+EL+PF +G  QCLGE   + + F+   S+VQ F+I F  EI+E+  +  +    G+IR+    + +F+ R
Sbjct:   18 YWVCRKPPIPKGLKEIPMESGLPIIGAIHKI-EPPMHHYLLKLGRKLGPIFRIKLGMRKIVVLNNYEMIKKALIDDANNFSGRWSQRFIKEITHDSGIIFKDGKIWATQRSFILKVLRDFGLGKSKSIEIVQNECFNFLDELDTLSGQIVDFSELIPIYTTNIISRFIMNKRFTRDDPNIQLIEETINNSTKNKDIIQLILLMFPCFDNSSLICQLIYLLTSKWKSFVKIQN-YFGEEIEEHRTNLDLTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRTSVELFIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFAEEISEDKYSQTIIGNEGVIRTSDIKNFLFKRR 506