N-chimaerin

Overview


Name	N-chimaerin
Smed ID	SMED30005615
Length (bp)	2272

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of N-chimaerin (SMED30005615) t-SNE clustered cells

Violin plots show distribution of expression levels for N-chimaerin (SMED30005615) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of N-chimaerin (SMED30005615) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for N-chimaerin (SMED30005615) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30005615

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
parenchymal cell	SMED30005615	h1SMcG0017080	dd_Smed_v4_9033_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30005615	h1SMcG0017080	dd_Smed_v4_9033_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of N-chimaerin vs. Ensembl Human
Match: CHN2 (chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944])

HSP 1 Score: 159.844 bits (403), Expect = 2.314e-44
Identity = 67/140 (47.86%), Postives = 101/140 (72.14%), Query Frame = 3

Query: 1098 SEFSGVTSKSS-TNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ S +  +++ T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+
Sbjct:   55 SQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 194

[Close]

BLAST of N-chimaerin vs. Ensembl Human
Match: CHN1 (chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943])

HSP 1 Score: 160.999 bits (406), Expect = 4.743e-44
Identity = 66/140 (47.14%), Postives = 99/140 (70.71%), Query Frame = 3

Query: 1098 SEFSGVTSKSSTNQN-CYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ + +  +++  +N    + EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD+K +K+V+  +LT+L K      PM++   + E+E+RG+  EG+YRVSG S+LI++VK   D+
Sbjct:   24 SQLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR 163

[Close]

BLAST of N-chimaerin vs. Ensembl Human
Match: CHN1 (chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943])

HSP 1 Score: 162.54 bits (410), Expect = 8.386e-44
Identity = 66/140 (47.14%), Postives = 99/140 (70.71%), Query Frame = 3

Query: 1098 SEFSGVTSKSSTNQN-CYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ + +  +++  +N    + EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD+K +K+V+  +LT+L K      PM++   + E+E+RG+  EG+YRVSG S+LI++VK   D+
Sbjct:   57 SQLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR 196

[Close]

BLAST of N-chimaerin vs. Ensembl Human
Match: CHN2 (chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944])

HSP 1 Score: 162.54 bits (410), Expect = 9.196e-44
Identity = 67/140 (47.86%), Postives = 101/140 (72.14%), Query Frame = 3

Query: 1098 SEFSGVTSKSS-TNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ S +  +++ T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+
Sbjct:   55 SQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 194

[Close]

BLAST of N-chimaerin vs. Ensembl Human
Match: CHN1 (chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943])

HSP 1 Score: 160.229 bits (404), Expect = 1.618e-43
Identity = 64/119 (53.78%), Postives = 89/119 (74.79%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD+K +K+V+  +LT+L K      PM++   + E+E+RG+  EG+YRVSG S+LI++VK   D+
Sbjct:   29 EKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR 147

[Close]

BLAST of N-chimaerin vs. Ensembl Celegans
Match: chin-1 (CHImaeriN (Rac-GTPase-activating protein) homolog [Source:UniProtKB/TrEMBL;Acc:Q965N4])

HSP 1 Score: 145.976 bits (367), Expect = 1.624e-37
Identity = 56/117 (47.86%), Postives = 89/117 (76.07%), Query Frame = 3

Query: 1161 KQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLD 1511
            + HNF ++TFK PH+CD+C +F+WGLV QG++C+DCGF AH+KCS++   DC+PD K +KR+FG+++T+L       +P I+   + EVE+RG+++EGIYRVSG+ + ++++K   D
Sbjct:  170 RAHNFTSYTFKAPHYCDYCRNFLWGLVHQGMRCEDCGFAAHKKCSEKTLHDCVPDSKYVKRMFGVDITTLCMAHGADLPPIVPLCIGEVESRGLDVEGIYRVSGSYDHMEKLKQQFD 286

HSP 2 Score: 122.479 bits (306), Expect = 1.564e-29
Identity = 64/162 (39.51%), Postives = 97/162 (59.88%), Query Frame = 3

Query:  102 WRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQMTR----QKPVSTKKN 575
            W+ +LY LQ++APK   V+ +  +  +P ++G E+HG I R+E E ++     G+YL+R+  R R   TL + FD    NYKL+YD   GQ YVG K FD ++ LV DGLI ++++   A  +KR+A+  IYEDSP+  +RY     T     ++PV+   N
Sbjct:   17 WKQNLYLLQEKAPKPNAVLCRKPLQQRPRHFGAEFHGLIDRNEAEKMLLEAGEGSYLVRESNRSRDACTLCMIFDAKVMNYKLYYD---GQFYVGEKRFDTMDLLVADGLISMFVDLHAADYIKRMADEAIYEDSPY--SRYTNAAATTSDIVRRPVTRAHN 173

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BLAST of N-chimaerin vs. Ensembl Celegans
Match: rsf-1 (RASSF (Ras-association domain family) homolog [Source:UniProtKB/TrEMBL;Acc:Q58AA9])

HSP 1 Score: 67.3958 bits (163), Expect = 2.406e-11
Identity = 32/88 (36.36%), Postives = 47/88 (53.41%), Query Frame = 3

Query: 1062 ASLD-NQLLNDT--KSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            A LD N + NDT  +  F  +    +T     A +   H+FKTH+   P WCD C  F+WG++ + +KC+ C +  H +C D V  DC
Sbjct:   68 ADLDSNHVWNDTIERQHFGPLKDLITTGGG--ANKINNHSFKTHSLLHPTWCDKCGDFIWGILKEALKCEHCNYTCHARCRDLVTLDC 153

[Close]

Query: 1062 ASLD-NQLLNDT--KSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            A LD N + NDT  +  F  +    +T     A +   H+FKTH+   P WCD C  F+WG++ + +KC+ C +  H +C D V  DC
Sbjct:   68 ADLDSNHVWNDTIERQHFGPLKDLITTGGG--ANKINNHSFKTHSLLHPTWCDKCGDFIWGILKEALKCEHCNYTCHARCRDLVTLDC 153

[Close]

BLAST of N-chimaerin vs. Ensembl Celegans
Match: rsf-1 (RASSF (Ras-association domain family) homolog [Source:UniProtKB/TrEMBL;Acc:Q58AA9])

HSP 1 Score: 67.0106 bits (162), Expect = 2.895e-11
Identity = 32/88 (36.36%), Postives = 47/88 (53.41%), Query Frame = 3

Query: 1062 ASLD-NQLLNDT--KSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            A LD N + NDT  +  F  +    +T     A +   H+FKTH+   P WCD C  F+WG++ + +KC+ C +  H +C D V  DC
Sbjct:  129 ADLDSNHVWNDTIERQHFGPLKDLITTGGG--ANKINNHSFKTHSLLHPTWCDKCGDFIWGILKEALKCEHCNYTCHARCRDLVTLDC 214

[Close]

BLAST of N-chimaerin vs. Ensembl Celegans
Match: dkf-2 (Serine/threonine-protein kinase dkf-2 [Source:UniProtKB/Swiss-Prot;Acc:O45818])

HSP 1 Score: 65.855 bits (159), Expect = 9.426e-11
Identity = 21/50 (42.00%), Postives = 34/50 (68.00%), Query Frame = 3

Query: 1167 HNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            H    H++K P +CDFC   ++GLV QG+KC  CG   H++C+ ++P++C
Sbjct:  322 HTLFVHSYKVPTFCDFCGELLFGLVKQGLKCFGCGLNYHKRCASKIPNNC 371

HSP 2 Score: 60.077 bits (144), Expect = 5.236e-9
Identity = 23/62 (37.10%), Postives = 36/62 (58.06%), Query Frame = 3

Query: 1167 HNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFG 1352
            H F+ H++K P  C  C   + GL+ QG++C+DC +  H+KCS+ V  DC  + K  +   G
Sbjct:  474 HTFQVHSYKLPTVCQHCKKLLKGLIRQGMQCRDCKYNCHKKCSEHVAKDCSGNTKASQFFLG 535

[Close]

BLAST of N-chimaerin vs. Ensembl Fly
Match: RhoGAP5A (gene:FBgn0029778 transcript:FBtr0070784)

HSP 1 Score: 158.303 bits (399), Expect = 1.526e-41
Identity = 72/148 (48.65%), Postives = 101/148 (68.24%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRG-VPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDAVLSDSNVTAHSNAKTLEMT 1598
            EK H+FK HTFKG +WC+FC +F+WG  AQGVKC+ CGF AH KCS+ VP  C+PD+KR++ VFG +LT++ ++E    +P ++ R VEEVEARGM  EGIYRVSG ++ I+ +K  LD+       +   +D + TA+ N   +  T
Sbjct:  239 EKPHHFKVHTFKGLNWCEFCANFLWGFTAQGVKCEACGFVAHSKCSELVPPKCVPDLKRIRGVFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDR-------EGEKTDMSETAYGNVNVIAGT 379

HSP 2 Score: 86.2705 bits (212), Expect = 2.211e-17
Identity = 48/160 (30.00%), Postives = 83/160 (51.88%), Query Frame = 3

Query:   90 INEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPA---------------YYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGY-KYFDKINDLVQDGLIHLYIESRGAAELKRIAEC--NIYEDSPFF 515
            + +VW+ +LYKLQ +AP   P+  +  +   PA                YG EYHG +   E E ++     G+Y +R   +  G +TL ++F++  K+YKL Y    G +  G  K FD ++D+V DGLI+ +++   +  +++I +   N Y+ SP+ 
Sbjct:   30 VQKVWKPELYKLQLEAPAPCPLRCQRTLPLPPAKSTAEAVEANNLAGRLYGSEYHGLMGHLEAEQLLANARDGSYFVRRSPQSDGYYTLSLRFNKRPKHYKLLYKPGVGHYLRGQDKRFDTVHDMVADGLINFHMQLHASPIIQQINQQTKNCYQQSPYM 189

[Close]

BLAST of N-chimaerin vs. Ensembl Fly
Match: RhoGAP5A (gene:FBgn0029778 transcript:FBtr0070785)

HSP 1 Score: 159.073 bits (401), Expect = 2.372e-41
Identity = 72/148 (48.65%), Postives = 101/148 (68.24%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRG-VPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDAVLSDSNVTAHSNAKTLEMT 1598
            EK H+FK HTFKG +WC+FC +F+WG  AQGVKC+ CGF AH KCS+ VP  C+PD+KR++ VFG +LT++ ++E    +P ++ R VEEVEARGM  EGIYRVSG ++ I+ +K  LD+       +   +D + TA+ N   +  T
Sbjct:  239 EKPHHFKVHTFKGLNWCEFCANFLWGFTAQGVKCEACGFVAHSKCSELVPPKCVPDLKRIRGVFGTDLTTMVQLEPHHQIPFVVRRCVEEVEARGMLQEGIYRVSGFADEIEALKLALDR-------EGEKTDMSETAYGNVNVIAGT 379

HSP 2 Score: 86.6557 bits (213), Expect = 2.252e-17
Identity = 48/160 (30.00%), Postives = 83/160 (51.88%), Query Frame = 3

Query:   90 INEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPA---------------YYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGY-KYFDKINDLVQDGLIHLYIESRGAAELKRIAEC--NIYEDSPFF 515
            + +VW+ +LYKLQ +AP   P+  +  +   PA                YG EYHG +   E E ++     G+Y +R   +  G +TL ++F++  K+YKL Y    G +  G  K FD ++D+V DGLI+ +++   +  +++I +   N Y+ SP+ 
Sbjct:   30 VQKVWKPELYKLQLEAPAPCPLRCQRTLPLPPAKSTAEAVEANNLAGRLYGSEYHGLMGHLEAEQLLANARDGSYFVRRSPQSDGYYTLSLRFNKRPKHYKLLYKPGVGHYLRGQDKRFDTVHDMVADGLINFHMQLHASPIIQQINQQTKNCYQQSPYM 189

[Close]

BLAST of N-chimaerin vs. Ensembl Fly
Match: PKD (gene:FBgn0038603 transcript:FBtr0337037)

HSP 1 Score: 69.3218 bits (168), Expect = 5.426e-13
Identity = 23/52 (44.23%), Postives = 36/52 (69.23%), Query Frame = 3

Query: 1161 KQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            K H+   H++KGP +CDFC   ++GLV QG+KC  CG   H++C  ++P++C
Sbjct:  103 KPHSLNVHSYKGPTFCDFCGEMLFGLVRQGLKCDGCGQNYHKRCVVKIPNNC 154

[Close]

BLAST of N-chimaerin vs. Ensembl Fly
Match: PKD (gene:FBgn0038603 transcript:FBtr0337036)

HSP 1 Score: 69.3218 bits (168), Expect = 5.426e-13
Identity = 23/52 (44.23%), Postives = 36/52 (69.23%), Query Frame = 3

Query: 1161 KQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            K H+   H++KGP +CDFC   ++GLV QG+KC  CG   H++C  ++P++C
Sbjct:  103 KPHSLNVHSYKGPTFCDFCGEMLFGLVRQGLKCDGCGQNYHKRCVVKIPNNC 154

[Close]

BLAST of N-chimaerin vs. Ensembl Fly
Match: PKD (gene:FBgn0038603 transcript:FBtr0330312)

HSP 1 Score: 68.1662 bits (165), Expect = 2.119e-11
Identity = 23/52 (44.23%), Postives = 36/52 (69.23%), Query Frame = 3

Query: 1161 KQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            K H+   H++KGP +CDFC   ++GLV QG+KC  CG   H++C  ++P++C
Sbjct:  103 KPHSLNVHSYKGPTFCDFCGEMLFGLVRQGLKCDGCGQNYHKRCVVKIPNNC 154

HSP 2 Score: 64.3142 bits (155), Expect = 3.702e-10
Identity = 41/144 (28.47%), Postives = 61/144 (42.36%), Query Frame = 3

Query:  900 DESVQNYHQS-----DTSTDRQVDTSSSSSMDTRGETKNSMEESGYTVSTTDTNSLSSDASLDNQLLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            D   QNYH+        + +R  D +S  S   +     S       VST D+   +  +S  N      ++  SG       ++N        H F  HT+  P  C  C   + GL  QG++C+DC +  H+KC D+VP DC
Sbjct:  136 DGCGQNYHKRCVVKIPNNCNRSNDATSRRSFTLQAPRSPSGSSQQSLVSTEDSTGRNDSSSSLNIPGRHQRTHSSG-------SRNGLMVLRIPHTFMVHTYGIPTVCQLCKKLLKGLFKQGLQCRDCQYNTHKKCMDKVPHDC 272

[Close]

BLAST of N-chimaerin vs. Ensembl Zebrafish
Match: chn1 (chimerin 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1934])

HSP 1 Score: 163.696 bits (413), Expect = 2.389e-44
Identity = 64/119 (53.78%), Postives = 90/119 (75.63%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD+K +K+V+  +LT+L K      PM++   + E+EARG++ EG+YR+SG S+LI++VK   D+
Sbjct:   78 EKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHNAKRPMVVDMCIREIEARGLQSEGLYRISGFSDLIEDVKLSFDR 196

[Close]

BLAST of N-chimaerin vs. Ensembl Zebrafish
Match: chn2 (chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5])

HSP 1 Score: 163.31 bits (412), Expect = 3.922e-43
Identity = 71/152 (46.71%), Postives = 102/152 (67.11%), Query Frame = 3

Query: 1116 TSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDA-VLSDSNVTA 1568
            T K    ++C    EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VPSDC PD++R+K+VF  +LT+L K      PM++   + E+E RG++ EG+YRVSG +E I++V+   D+   +  I A +  D N+ A
Sbjct:  182 TLKDGPEKHC--NYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKLVPSDCQPDLRRIKKVFSCDLTTLVKAHNTPRPMVLDMCIREIEHRGLKSEGLYRVSGFTEHIEDVRLSFDRDGEKADISANIYPDINIIA 331

HSP 2 Score: 127.487 bits (319), Expect = 7.450e-31
Identity = 61/139 (43.88%), Postives = 94/139 (67.63%), Query Frame = 3

Query:   84 EYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            +Y   +W++ LY+LQQ+AP+ K +    E+ S+P YYG E+HG I+R++ + ++ A   GAYLIR+  R  GT+TL ++F   T NY+LFYD   G+H+VG K F+ ++DLV DGLI LYIE++ A  + ++    IY+
Sbjct:    4 DYQPPIWKSYLYQLQQEAPRPKRITCPQEMESRPKYYGREFHGLISREQADELL-AGTEGAYLIRESQRQPGTYTLALRFGGQTLNYRLFYD---GKHFVGEKRFESVHDLVTDGLITLYIETKAAEYIAKMTTNPIYQ 138

[Close]

BLAST of N-chimaerin vs. Ensembl Zebrafish
Match: chn1 (chimerin 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1934])

HSP 1 Score: 163.696 bits (413), Expect = 4.349e-43
Identity = 64/119 (53.78%), Postives = 90/119 (75.63%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD+K +K+V+  +LT+L K      PM++   + E+EARG++ EG+YR+SG S+LI++VK   D+
Sbjct:  203 EKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHNAKRPMVVDMCIREIEARGLQSEGLYRISGFSDLIEDVKLSFDR 321

HSP 2 Score: 126.331 bits (316), Expect = 1.975e-30
Identity = 63/139 (45.32%), Postives = 95/139 (68.35%), Query Frame = 3

Query:   84 EYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            EY   VW++ LY+LQQ+AP  + V   +EV ++P YYG EYHG I+R++  +++ +   G+YLIR+  R  GT+TL ++F   T+N++LFYD   G+H+VG K F+ I+DLV DGLI LYIE++ A  + ++    IYE
Sbjct:   10 EYRPPVWKSYLYQLQQEAPHPRRVTCTSEVENRPKYYGREYHGLISRED-GDLLLSVAEGSYLIRESQRQPGTYTLALRFGNQTRNFRLFYD---GKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTINPIYE 144

[Close]

BLAST of N-chimaerin vs. Ensembl Zebrafish
Match: chn2 (chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5])

HSP 1 Score: 163.31 bits (412), Expect = 5.052e-43
Identity = 71/152 (46.71%), Postives = 102/152 (67.11%), Query Frame = 3

Query: 1116 TSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDA-VLSDSNVTA 1568
            T K    ++C    EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VPSDC PD++R+K+VF  +LT+L K      PM++   + E+E RG++ EG+YRVSG +E I++V+   D+   +  I A +  D N+ A
Sbjct:  198 TLKDGPEKHC--NYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKLVPSDCQPDLRRIKKVFSCDLTTLVKAHNTPRPMVLDMCIREIEHRGLKSEGLYRVSGFTEHIEDVRLSFDRDGEKADISANIYPDINIIA 347

HSP 2 Score: 127.487 bits (319), Expect = 9.411e-31
Identity = 61/139 (43.88%), Postives = 94/139 (67.63%), Query Frame = 3

Query:   84 EYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            +Y   +W++ LY+LQQ+AP+ K +    E+ S+P YYG E+HG I+R++ + ++ A   GAYLIR+  R  GT+TL ++F   T NY+LFYD   G+H+VG K F+ ++DLV DGLI LYIE++ A  + ++    IY+
Sbjct:   20 DYQPPIWKSYLYQLQQEAPRPKRITCPQEMESRPKYYGREFHGLISREQADELL-AGTEGAYLIRESQRQPGTYTLALRFGGQTLNYRLFYD---GKHFVGEKRFESVHDLVTDGLITLYIETKAAEYIAKMTTNPIYQ 154

[Close]

BLAST of N-chimaerin vs. Ensembl Zebrafish
Match: myo9ab (myosin IXAb [Source:NCBI gene;Acc:562199])

HSP 1 Score: 83.1889 bits (204), Expect = 8.268e-16
Identity = 41/123 (33.33%), Postives = 71/123 (57.72%), Query Frame = 3

Query: 1149 AEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLP--DMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLD 1511
             E+   H FK+  +  P +C+FC+  +W ++ +   C+ C +  H+KC  R+ + C    D +   R FG+EL+ L   ++R VP+++ +L+  +E  G+  EGIYR SG++  I E+K  LD
Sbjct: 1754 VEEHMGHIFKSTQYSIPTYCEFCSSLIW-MMDKACVCKLCRYACHKKCCLRMTTKCSKKFDPELSSRQFGVELSRLTS-DERSVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELKQGLD 1874

[Close]

BLAST of N-chimaerin vs. Ensembl Xenopus
Match: edem3 (ER degradation enhancer, mannosidase alpha-like 3 [Source:Xenbase;Acc:XB-GENE-5811499])

HSP 1 Score: 162.54 bits (410), Expect = 2.660e-44
Identity = 65/140 (46.43%), Postives = 100/140 (71.43%), Query Frame = 3

Query: 1098 SEFSGVTSKSSTNQN-CYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ + +  +++  +N  +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   ++E+E RG++ EG+YRVSG +E I++VK   D+
Sbjct:   14 SQITSLVRRAAIAKNDNHFNYEKAHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKYVPNDCQPDLKRIKKVYSCDLTTLVKAHNTPRPMVVDMCIQEIEGRGLKSEGLYRVSGFTEHIEDVKMSFDR 153

[Close]

BLAST of N-chimaerin vs. Ensembl Xenopus
Match: edem3 (ER degradation enhancer, mannosidase alpha-like 3 [Source:Xenbase;Acc:XB-GENE-5811499])

HSP 1 Score: 163.696 bits (413), Expect = 1.314e-43
Identity = 63/119 (52.94%), Postives = 90/119 (75.63%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   ++E+E RG++ EG+YRVSG +E I++VK   D+
Sbjct:  137 EKAHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKYVPNDCQPDLKRIKKVYSCDLTTLVKAHNTPRPMVVDMCIQEIEGRGLKSEGLYRVSGFTEHIEDVKMSFDR 255

[Close]

BLAST of N-chimaerin vs. Ensembl Xenopus
Match: edem3 (ER degradation enhancer, mannosidase alpha-like 3 [Source:Xenbase;Acc:XB-GENE-5811499])

HSP 1 Score: 164.081 bits (414), Expect = 1.582e-43
Identity = 68/136 (50.00%), Postives = 97/136 (71.32%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDAVL-SDSNV 1562
            EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   ++E+E RG++ EG+YRVSG +E I++VK   D+   R  I + L  D N+
Sbjct:  163 EKAHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKYVPNDCQPDLKRIKKVYSCDLTTLVKAHNTPRPMVVDMCIQEIEGRGLKSEGLYRVSGFTEHIEDVKMSFDRDGDRADISSTLYPDINI 298

HSP 2 Score: 88.5817 bits (218), Expect = 5.276e-18
Identity = 45/99 (45.45%), Postives = 65/99 (65.66%), Query Frame = 3

Query:  204 YHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            +HG I+R++ + V+     GAYLIR+  R  G +TL ++F   T NY+LFYD   G+H+VG K F+ I+DLV DGLI LYIE++ A  + ++    IYE
Sbjct:   12 FHGIISREQADVVLCGM-EGAYLIRESQRQPGCYTLALRFGHQTLNYRLFYD---GKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTTNPIYE 106

[Close]

BLAST of N-chimaerin vs. Ensembl Xenopus
Match: edem3 (ER degradation enhancer, mannosidase alpha-like 3 [Source:Xenbase;Acc:XB-GENE-5811499])

HSP 1 Score: 163.696 bits (413), Expect = 2.855e-43
Identity = 66/130 (50.77%), Postives = 94/130 (72.31%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDAVL 1547
            EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   ++E+E RG++ EG+YRVSG +E I++VK   D+   R  I + L
Sbjct:  167 EKAHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKYVPNDCQPDLKRIKKVYSCDLTTLVKAHNTPRPMVVDMCIQEIEGRGLKSEGLYRVSGFTEHIEDVKMSFDRDGDRADISSTL 296

HSP 2 Score: 88.5817 bits (218), Expect = 6.460e-18
Identity = 45/99 (45.45%), Postives = 65/99 (65.66%), Query Frame = 3

Query:  204 YHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            +HG I+R++ + V+     GAYLIR+  R  G +TL ++F   T NY+LFYD   G+H+VG K F+ I+DLV DGLI LYIE++ A  + ++    IYE
Sbjct:   16 FHGIISREQADVVLCGM-EGAYLIRESQRQPGCYTLALRFGHQTLNYRLFYD---GKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTTNPIYE 110

[Close]

BLAST of N-chimaerin vs. Ensembl Xenopus
Match: edem3 (ER degradation enhancer, mannosidase alpha-like 3 [Source:Xenbase;Acc:XB-GENE-5811499])

HSP 1 Score: 163.696 bits (413), Expect = 2.994e-43
Identity = 68/136 (50.00%), Postives = 97/136 (71.32%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDAVL-SDSNV 1562
            EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   ++E+E RG++ EG+YRVSG +E I++VK   D+   R  I + L  D N+
Sbjct:  167 EKAHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKYVPNDCQPDLKRIKKVYSCDLTTLVKAHNTPRPMVVDMCIQEIEGRGLKSEGLYRVSGFTEHIEDVKMSFDRDGDRADISSTLYPDINI 302

HSP 2 Score: 88.1965 bits (217), Expect = 7.745e-18
Identity = 45/99 (45.45%), Postives = 65/99 (65.66%), Query Frame = 3

Query:  204 YHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            +HG I+R++ + V+     GAYLIR+  R  G +TL ++F   T NY+LFYD   G+H+VG K F+ I+DLV DGLI LYIE++ A  + ++    IYE
Sbjct:   16 FHGIISREQADVVLCGM-EGAYLIRESQRQPGCYTLALRFGHQTLNYRLFYD---GKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTTNPIYE 110

[Close]

BLAST of N-chimaerin vs. Ensembl Mouse
Match: Chn2 (chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243])

HSP 1 Score: 162.925 bits (411), Expect = 2.421e-45
Identity = 67/136 (49.26%), Postives = 97/136 (71.32%), Query Frame = 3

Query: 1107 SGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S V   + T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+
Sbjct:    4 SLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 139

[Close]

BLAST of N-chimaerin vs. Ensembl Mouse
Match: Chn2 (chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243])

HSP 1 Score: 163.31 bits (412), Expect = 7.256e-45
Identity = 67/136 (49.26%), Postives = 97/136 (71.32%), Query Frame = 3

Query: 1107 SGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S V   + T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+
Sbjct:    4 SLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 139

[Close]

BLAST of N-chimaerin vs. Ensembl Mouse
Match: Chn2 (chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243])

HSP 1 Score: 163.31 bits (412), Expect = 8.396e-45
Identity = 67/136 (49.26%), Postives = 97/136 (71.32%), Query Frame = 3

Query: 1107 SGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S V   + T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+
Sbjct:    9 SLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 144

[Close]

BLAST of N-chimaerin vs. Ensembl Mouse
Match: Chn2 (chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243])

HSP 1 Score: 159.844 bits (403), Expect = 1.328e-44
Identity = 67/140 (47.86%), Postives = 101/140 (72.14%), Query Frame = 3

Query: 1098 SEFSGVTSKSS-TNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ S +  +++ T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+
Sbjct:   55 SQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 194

[Close]

BLAST of N-chimaerin vs. Ensembl Mouse
Match: Chn2 (chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243])

HSP 1 Score: 162.155 bits (409), Expect = 2.696e-44
Identity = 67/140 (47.86%), Postives = 101/140 (72.14%), Query Frame = 3

Query: 1098 SEFSGVTSKSS-TNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ S +  +++ T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+
Sbjct:   55 SQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 194

[Close]

BLAST of N-chimaerin vs. UniProt/SwissProt
Match: sp|Q03070|CHIO_RAT (Beta-chimaerin OS=Rattus norvegicus OX=10116 GN=Chn2 PE=2 SV=1)

HSP 1 Score: 163.696 bits (413), Expect = 7.999e-44
Identity = 67/136 (49.26%), Postives = 97/136 (71.32%), Query Frame = 3

Query: 1107 SGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S V   + T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+
Sbjct:   22 SLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 157

[Close]

BLAST of N-chimaerin vs. UniProt/SwissProt
Match: sp|Q17QN0|CHIN_BOVIN (N-chimaerin OS=Bos taurus OX=9913 GN=CHN1 PE=2 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 2.218e-43
Identity = 67/140 (47.86%), Postives = 99/140 (70.71%), Query Frame = 3

Query: 1098 SEFSGVTSKSSTNQN-CYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ + +  +++  +N    + EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD+K +K+V+  +LT+L K      PM++   + E+EARG+  EG+YRVSG S+LI++VK   D+
Sbjct:   57 SQLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKARTTKRPMVVDMCIREIEARGLNSEGLYRVSGFSDLIEDVKMAFDR 196

[Close]

BLAST of N-chimaerin vs. UniProt/SwissProt
Match: sp|Q80XD1|CHIO_MOUSE (Beta-chimaerin OS=Mus musculus OX=10090 GN=Chn2 PE=1 SV=2)

HSP 1 Score: 162.925 bits (411), Expect = 3.848e-43
Identity = 67/140 (47.86%), Postives = 101/140 (72.14%), Query Frame = 3

Query: 1098 SEFSGVTSKSS-TNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ S +  +++ T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+
Sbjct:   55 SQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 194

[Close]

BLAST of N-chimaerin vs. UniProt/SwissProt
Match: sp|P30337|CHIN_RAT (N-chimaerin OS=Rattus norvegicus OX=10116 GN=Chn1 PE=1 SV=2)

HSP 1 Score: 161.77 bits (408), Expect = 9.893e-43
Identity = 66/140 (47.14%), Postives = 99/140 (70.71%), Query Frame = 3

Query: 1098 SEFSGVTSKSSTNQN-CYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            S+ + +  +++  +N    + EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD+K +K+V+  +LT+L K      PM++   + E+E+RG+  EG+YRVSG S+LI++VK   D+
Sbjct:   57 SQLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDR 196

[Close]

BLAST of N-chimaerin vs. UniProt/SwissProt
Match: sp|P52757|CHIO_HUMAN (Beta-chimaerin OS=Homo sapiens OX=9606 GN=CHN2 PE=1 SV=2)

HSP 1 Score: 164.081 bits (414), Expect = 2.238e-42
Identity = 76/167 (45.51%), Postives = 108/167 (64.67%), Query Frame = 3

Query: 1086 NDTKSEFSGVTSKSS-------TNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDA-VLSDSNV 1562
            N T  E + V   SS       T+ + +   EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VP+DC PD+KR+K+V+  +LT+L K      PM++   + E+EARG++ EG+YRVSG +E I++VK   D+   +  I A V  D N+
Sbjct:  181 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI 347

HSP 2 Score: 124.02 bits (310), Expect = 1.132e-28
Identity = 59/139 (42.45%), Postives = 93/139 (66.91%), Query Frame = 3

Query:   84 EYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            EY   +W++ LY+LQQ+AP+ K ++   EV ++P YYG E+HG I+R++ + ++     GAY++R+  R  G +TL ++F   T NY+LF+D   G+H+VG K F+ I+DLV DGLI LYIE++ A  + ++    IYE
Sbjct:   20 EYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELL-GGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHD---GKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYE 154

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BLAST of N-chimaerin vs. TrEMBL
Match: A0A5K3ESY6 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 331.643 bits (849), Expect = 6.696e-100
Identity = 183/486 (37.65%), Postives = 274/486 (56.38%), Query Frame = 3

Query:   99 VWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQMTRQKPVSTKKNHGHSNNREINEKGSPKTSVNSHSYTIKNKDNESIQIVTCQIDTSNIKLNPFYLKEDSKSSNNPFLASGDHIDQYETN---ICPPIRHSSLISSQLARKKQLQIPSNIPCSDDESVQNYHQSDTSTDRQVDTSSSSSMDTR--GETKNSMEESGYTV----STTDTNSLSSDASLD----NQLLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEAR-GMEIEGIYRVSGNSELIDEVKADLDK 1514
            +W+  LY LQ++APK  P+V   ++   P  YG  YHG ++R   E ++  QP+GAYLIRD  R  G FTL I+FD+STKNYKLFYD  +  H+VG K F+ ++ LV DGLI+LYIESRGA  L++++E N YE SP++K RY+T+      P  T+++   S+   ++    P             + +   +++     T   +L+ F    D ++ N      GD  D  + +   +C PI        + AR   L  P   P  +  +  +   S         +S  +S+++R  G + N   + G ++    S   T  +S D  LD       L+   +      + ++     + + EK H F+ HTF+GPHWCDFCTHF+WGLV+QGV+C DCGFQAH++CS  VP+DCLPDMKRLKRVFG++LTSL + E R VP ++++ + E+E R G+  EG+YRV GN E++++ +  LDK
Sbjct:   10 IWQNKLYNLQREAPKPIPIVCSAQLDHVPKQYGAAYHGPLSRQGTEELLAGQPSGAYLIRDSQRADGAFTLAIRFDDSTKNYKLFYDATSKLHFVGEKKFESVDQLVADGLIYLYIESRGADILQKLSEANNYEYSPYYKTRYHTVNAVPPPP-PTRQSLAPSSRLVVSAISGPN----------HRRQSSVDELLDGYQKTPTTQLSEFNPPVDKEAPN------GDISDSPKNSSAVLCGPIE-------KPARSTSLPFPRP-PLIESSTDSSLSPSAKPGSSTSTSSGDASLNSRQSGGSGNGRRKGGSSIHHHRSLASTLPVSLDGGLDVDGNRASLHVVGAVPPATATAATPLAIIHVDVEKAHAFRVHTFRGPHWCDFCTHFIWGLVSQGVRCVDCGFQAHKRCSISVPNDCLPDMKRLKRVFGVDLTSLVRAENRTVPQVLVKCITELERRGGLMTEGVYRVPGNQEIVEDFRIALDK 470

[Close]

BLAST of N-chimaerin vs. TrEMBL
Match: A0A0R3X7A1 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS9409 PE=4 SV=1)

HSP 1 Score: 324.324 bits (830), Expect = 1.166e-98
Identity = 190/488 (38.93%), Postives = 275/488 (56.35%), Query Frame = 3

Query:  114 LYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQM----TRQKPVS-TKKNHGHSNNREINEKGSPKTSVNSHSYTIKNKDNESIQIVTCQIDTSNIKLNPFYLKEDSKSSNNPFLASGDHIDQYETNICPPIRHSSLISSQLARKKQLQI---PSNIPCSDDESVQNYHQSDTSTDRQVDTSSSSSMDTRGETKNSMEESGYTVSTTDTNSLSSDASLDNQLLND-------TKSEFSGVTSKSSTNQN-----CYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEAR-GMEIEGIYRVSGNSELIDEVKADLDK 1514
            +Y LQ++APK  P+V    +   P  YG  YHG ++R   E ++  QP+GAYLIRD  R  G FTL I+FD+STKNYKLFYD  +  HYVG K F+ ++ LV DGLI+LYIE+RGA  L++++E + YE SP++K RY+T+      TR    S +  N+   ++ E+ + GS K S    + +I++   + I      I     K  P  +   S S + P L S        +++    R +SL  S+   ++ L+    PS  P S  ++    H + +S       S  S    +GE +      G         S+    +L + L  +       T    S   + +S   N      + + EK HNF+ HTF+GPHWCDFCTHF+WGLV+QGVKC DCGFQAH++CS  VP+DCLPDMKRLKRVFG++LTSL + E R VP ++++ + E+E R G+  EG+YRV GN E++++ +  LDK
Sbjct:   27 VYNLQREAPKPVPIVCFEHLSHVPHQYGAAYHGPLSRQGTEELLNGQPSGAYLIRDSQRADGAFTLAIRFDDSTKNYKLFYDSASQLHYVGEKKFESVDQLVADGLIYLYIETRGADILQKLSEASNYEHSPYYKTRYHTVNAVPPPTRPSVASISSANYKRQSSLELLD-GSKKASPIRLTQSIRSAAADEI---ANGIINDPTKKPPAAV---SGSVDKPLLMSFPTFLHAFSSMQ--ARSTSLPFSKPRTERSLESSTSPSAKPNSSTDTSSVAHNNTSSGSSSGHASLKSRQSGKGEDEVDDGSGGENYRRKMIGSVQHHRTLASTLPMNLDGASAHTPGRISSEVAATSPTINPSSTLVHVDVEKAHNFRVHTFRGPHWCDFCTHFIWGLVSQGVKCTDCGFQAHKRCSISVPNDCLPDMKRLKRVFGVDLTSLVRAENRTVPQVLVKCIAELERRGGLVTEGVYRVPGNQEIVEDFRIALDK 505

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BLAST of N-chimaerin vs. TrEMBL
Match: W6UNW5 (N-chimaerin OS=Echinococcus granulosus OX=6210 GN=EGR_01856 PE=4 SV=1)

HSP 1 Score: 323.553 bits (828), Expect = 9.402e-97
Identity = 193/504 (38.29%), Postives = 282/504 (55.95%), Query Frame = 3

Query:  102 WRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQMTRQKPVSTKKNHGHSNNREINEKGSPKTSVNSHSYTIKNKDNESIQIVTCQIDTSNIKLNPFYLKEDSKSSNNPFLASGDHIDQYETNICPPIRHSSLISSQL---ARKKQLQIPSN-IPCSDDESVQNYHQSDTSTD---------RQVDTSSSSSMDTR--------------GETKNSMEESGYTVSTTDTNSLSSDASLDNQLLNDTKSEFSG---VTSKSSTNQN--CYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEAR-GMEIEGIYRVSGNSELIDEVKADLDK 1514
            W+  LY LQ++APK  PVV    +   P  YG  YHG ++R   E ++  QP+GAYLIRD  R  G FTL I+FD+STKNYKLFYD ++  HYVG K F+ ++ LV DGLI+L+IE+RGA  L++++E + YE SP++K RY+T+      P  T+ +                 +++S +Y    +   S+++     D S  K +P  L + ++S+    +A+G   D       PP + S+ +S  +   AR   L      I  +   S     + D STD             +S  +S+ TR              GE++      G     T  ++L    +LD   ++ T    SG   +T  ++T      + + EK HNF+ HTF+GPHWCDFCTHF+WGLV+QGVKC DCGFQAH++CS  VP+DCLPDMKRLKRVFG++LTSL + E R VP ++++ + E+E R G+  EG+YRV GN E++++ +  LDK
Sbjct:   11 WQNKLYNLQREAPKPFPVVCFEHLNHVPHQYGAAYHGPLSRQGTEELLSGQPSGAYLIRDSQRADGAFTLAIRFDDSTKNYKLFYDSSSQLHYVGEKKFESVDQLVADGLIYLHIETRGADILQKLSEASNYEHSPYYKTRYHTVNAV---PPPTRPS---------------VAAISSANY----RRQSSLEL----FDGSK-KPSPIRLIQSTQSAAADEVANGVIND-------PPKKPSAALSGSVDKPARSTSLPFSKQRIELALGPSTAPVAKPDCSTDTTGIARSSTSSGSSSGHASLKTRQPNKGEHTVDDGSGGESRRRKAFGGVQHHRTLASTLP--VNLDGANMH-TPGRISGEVAITCPTATPAPTLVHVDVEKAHNFRIHTFRGPHWCDFCTHFIWGLVSQGVKCTDCGFQAHKRCSLSVPNDCLPDMKRLKRVFGVDLTSLVRAENRTVPQVLVKCITELERRGGLVAEGVYRVPGNQEIVEDFRIALDK 477

[Close]

BLAST of N-chimaerin vs. TrEMBL
Match: A0A564XWJ9 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS660 PE=4 SV=1)

HSP 1 Score: 313.923 bits (803), Expect = 1.084e-93
Identity = 193/529 (36.48%), Postives = 270/529 (51.04%), Query Frame = 3

Query:  114 LYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQMT--------------------RQKPVSTKKNHGHSN--NREINEKGSPKTSVNSHSYTIKNKDNESIQIVTCQIDTSNIKLNPFYLKEDSKSSNNPFLASGDHIDQY---------------ETNICPPIRHSSLISSQ-----------LARKKQLQIPSNIPCSDDESVQNYHQSDTST------------DRQVDTSSSSSMDTRGETKNSMEESGYTVST-TDTNSLSSDASLDNQLLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEAR-GMEIEGIYRVSGNSELIDEVKADLDK 1514
            +Y LQ++APK  PV     +   P  YG  YHG ++R   E ++  QP+GAYLIRD  R  G +TL I+FD+STKNYKLFYD +   HYVG K F+ ++ LV DGLI+LYIE+RGA  L++++E + YE SP+++ RY+T+                       RQ  +     H H N  N   + + SPK      S              T    T+ I ++   L  D   SN   L + D ID+                 T  C   +   L+ S+           LAR   L  P   P  +D S  +     T+              RQ D    +  DT  + K  +        T   T  +S D ++  Q+     S     +   S++     + EK HNF+ HTF+GPHWCDFCTHF+WGLV+QGVKC DCGFQAH++CS  VP+DCLPDMKRLKRVFG++LTSL + E R VP ++++ + E+E R G+ +EG+YRV GN E++++ +  LDK
Sbjct:    4 VYNLQREAPKPFPVECTEPLEHVPEQYGSAYHGPLSRQGTEELLDGQPSGAYLIRDSQRADGAYTLAIRFDDSTKNYKLFYDPSKKLHYVGEKKFESVDLLVADGLIYLYIETRGADILQKLSEASNYEHSPYYRIRYHTVNAIPPSNRPSVSTVSGNKIVPPRRQSSLELLDGHNHWNQSNNTFHHQASPKPPTPISSRQSSTNQQPVGHNSTVATGTTTIHVS---LDTDEGISNGGVLLT-DSIDKKLLKGEKPSKKRPMSESTQSC---QAGPLVPSRNKTAFFRFLWNLARSTSL--PFAKPSCNDHSKHDATDVATAVSSGSSSGHASLKSRQSDKDVFAIDDTETQRKKFIGGGNVHHRTLASTLPVSLDGAMSPQI---PTSPLPPKSVPLSSHHLVVPDVEKAHNFRVHTFRGPHWCDFCTHFIWGLVSQGVKCTDCGFQAHKRCSISVPNDCLPDMKRLKRVFGVDLTSLVRAENRTVPQVLVKCITELERRGGLMMEGVYRVPGNQEIVEDFRIALDK 520

[Close]

BLAST of N-chimaerin vs. TrEMBL
Match: A0A3P6GMB0 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS6710 PE=4 SV=1)

HSP 1 Score: 293.893 bits (751), Expect = 6.679e-85
Identity = 167/447 (37.36%), Postives = 251/447 (56.15%), Query Frame = 3

Query:  216 ITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQMTRQKPVSTKKNHGHSNNREINEKGSPKTSVNSHSYTIKNKDNESIQIVTCQIDTSNIKLNPFYLKEDSKSSNNPFLASGDHIDQYETN---ICPPIRHSSLISSQLARKKQLQIPSNIPCSDDESVQNYHQSDTSTDRQVDTSSSSSMDTR--GETKNSMEESGYTV----STTDTNSLSSDASLD----NQLLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEAR-GMEIEGIYRVSGNSELIDEVKADLDK 1514
            ++R   E ++  QP+GAYLIRD  R  G FTL I+FD+STKNYKLFYD  +  H+VG K F+ ++ LV DGLI+LYIESRGA  L++++E N YE SP++K RY+T+      P  T+++   S+   ++    P             + +   +++     T   +L+ F    D ++ N      GD  D  + +   +C PI        + AR   L  P   P  +  +  +   S         +S  +S+++R  G + N   + G ++    S   T  +S D  LD       L+   +      + ++     + + EK H F+ HTF+GPHWCDFCTHF+WGLV+QGV+C DCGFQAH++CS  VP+DCLPDMKRLKRVFG++LTSL + E R VP ++++ + E+E R G+  EG+YRV GN E++++ +  LDK
Sbjct:    1 MSRQGTEELLAGQPSGAYLIRDSQRADGAFTLAIRFDDSTKNYKLFYDATSKLHFVGEKKFESVDQLVADGLIYLYIESRGADILQKLSEANNYEYSPYYKTRYHTVNAV-PPPPPTRQSLAPSSRLVVSAISGPN----------HRRQSSVDELLDGYQKTPTTQLSEFNPPVDKEAPN------GDISDSPKNSSAVLCGPIE-------KPARSTSLPFPRP-PLIESSTDSSLSPSAKPGSSTSTSSGDASLNSRQSGGSGNGRRKGGSSIHHHRSLASTLPVSLDGGLDVDGNRASLHVVGAVPPATATAATPLAIIHVDVEKAHAFRVHTFRGPHWCDFCTHFIWGLVSQGVRCVDCGFQAHKRCSISVPNDCLPDMKRLKRVFGVDLTSLVRAENRTVPQVLVKCITELERRGGLMTEGVYRVPGNQEIVEDFRIALDK 422

[Close]

BLAST of N-chimaerin vs. Ensembl Cavefish
Match: chn1 (chimerin 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1934])

HSP 1 Score: 165.236 bits (417), Expect = 7.829e-44
Identity = 67/138 (48.55%), Postives = 99/138 (71.74%), Query Frame = 3

Query: 1104 FSGVTSKSSTNQNCYAEQ-EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
             + +  +++  +N  A + EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD+K +K+V+  +LT+L K      PM++   + E+E+RG++ EG+YRVSG SELI++VK   D+
Sbjct:  169 LTSLVRRATLKENDRAPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHNSKRPMVVDMCIREIESRGLKSEGLYRVSGFSELIEDVKLSFDR 306

HSP 2 Score: 105.145 bits (261), Expect = 1.733e-23
Identity = 51/111 (45.95%), Postives = 76/111 (68.47%), Query Frame = 3

Query:  168 EVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            EV ++P YYG EYHG I+R+E + ++     G+YLIR+  R  GT+TL ++F   T+N++L+YD   G+H+VG K F+ I+DLV DGLI LYIE++ A  + ++    IYE
Sbjct:   23 EVENRPKYYGREYHGMISREEADQLLSVA-EGSYLIRESQRQPGTYTLALRFGNQTRNFRLYYD---GKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYE 129

[Close]

BLAST of N-chimaerin vs. Ensembl Cavefish
Match: myo9aa (myosin IXAa [Source:NCBI gene;Acc:100006612])

HSP 1 Score: 78.9518 bits (193), Expect = 1.502e-14
Identity = 39/123 (31.71%), Postives = 71/123 (57.72%), Query Frame = 3

Query: 1149 AEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLP--DMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLD 1511
             E+   H FK+  +  P +C++C+  +W ++ +   C+ C +  HRKC  ++ + C    D +   R FG+E++ L   ++R VP+++ +L+  +E  G+  EGIYR SG++  I E+K  LD
Sbjct: 1859 VEEHNGHIFKSTQYSIPTYCEYCSSLIW-MMDRACVCKLCRYACHRKCCLKMTTKCSKKYDPELSSRQFGVEVSRLTN-DERSVPVVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELKQGLD 1979

[Close]

BLAST of N-chimaerin vs. Ensembl Cavefish
Match: gmip (GEM interacting protein [Source:NCBI gene;Acc:103034590])

HSP 1 Score: 73.9442 bits (180), Expect = 3.692e-13
Identity = 55/197 (27.92%), Postives = 91/197 (46.19%), Query Frame = 3

Query:  927 SDTSTDRQVDTSSSSSMD---------TRGETKNSMEESGYTVSTTDTNSLSSDASLD-NQLLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELI 1487
            S  S  R++  S S SM            G  K     S  T+S+ D +    +A  +    LND+   F  V + S       A   +    K+   K    C  C +F   ++  G++C++CG   HRKC +   ++C  D +R   +FG+E + L + + + VP I+ R   E+E+R + ++G+YRVSG+   I
Sbjct:  451 SSVSDGRRIGYSDSESMGGSLESLSSPAHGNRKLPKAPSTGTMSSDDLDEKDINAEAECGDPLNDSNGSFCKVRTASRA-----ALTHRLRKMKSKMVK----CKQCENF---ILVNGIECEECGLAVHRKCLELCQTEC--DHRR-GNLFGVEFSLLPREQPQDVPFIVQRCTGEIESRALTVQGVYRVSGSKPRI 632

[Close]

BLAST of N-chimaerin vs. Ensembl Cavefish
Match: gmip (GEM interacting protein [Source:NCBI gene;Acc:103034590])

HSP 1 Score: 73.9442 bits (180), Expect = 3.965e-13
Identity = 53/197 (26.90%), Postives = 89/197 (45.18%), Query Frame = 3

Query:  927 SDTSTDRQVDTSSSSSMDTRGETKNSMEESGYTVSTTDTNSLSSDASLDNQ----------LLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELI 1487
            S  S  R++  S S SM    E+ +S       +    +    S   LD +           LND+   F  V + S       A   +    K+   K    C  C +F   ++  G++C++CG   HRKC +   ++C  D +R   +FG+E + L + + + VP I+ R   E+E+R + ++G+YRVSG+   I
Sbjct:  417 SSVSDGRRIGYSDSESMGGSLESLSSPAHGNRKLPKAPSTGTMSSDDLDEKDINAEAECGDPLNDSNGSFCKVRTASRA-----ALTHRLRKMKSKMVK----CKQCENF---ILVNGIECEECGLAVHRKCLELCQTEC--DHRR-GNLFGVEFSLLPREQPQDVPFIVQRCTGEIESRALTVQGVYRVSGSKPRI 598

[Close]

BLAST of N-chimaerin vs. Ensembl Cavefish
Match: gmip (GEM interacting protein [Source:NCBI gene;Acc:103034590])

HSP 1 Score: 73.9442 bits (180), Expect = 4.166e-13
Identity = 53/197 (26.90%), Postives = 89/197 (45.18%), Query Frame = 3

Query:  927 SDTSTDRQVDTSSSSSMDTRGETKNSMEESGYTVSTTDTNSLSSDASLDNQ----------LLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELI 1487
            S  S  R++  S S SM    E+ +S       +    +    S   LD +           LND+   F  V + S       A   +    K+   K    C  C +F   ++  G++C++CG   HRKC +   ++C  D +R   +FG+E + L + + + VP I+ R   E+E+R + ++G+YRVSG+   I
Sbjct:  417 SSVSDGRRIGYSDSESMGGSLESLSSPAHGNRKLPKAPSTGTMSSDDLDEKDINAEAECGDPLNDSNGSFCKVRTASRA-----ALTHRLRKMKSKMVK----CKQCENF---ILVNGIECEECGLAVHRKCLELCQTEC--DHRR-GNLFGVEFSLLPREQPQDVPFIVQRCTGEIESRALTVQGVYRVSGSKPRI 598

[Close]

BLAST of N-chimaerin vs. Ensembl Sea Lamprey
Match: chn2 (chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5])

HSP 1 Score: 157.532 bits (397), Expect = 2.901e-43
Identity = 66/122 (54.10%), Postives = 91/122 (74.59%), Query Frame = 3

Query: 1158 EKQHNFKT-HTFKGPHWCDFCTHFMWGLVAQGVKCQ--DCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            EK HNFK  HTF+GPHWC++C +FMWGL+AQGVKC   DCG   H++C   VP+DC PD +RL +VFG +LT+L K  +  +PM++   + E+EARG++ EG+YRVSG S+L++EV+   DK
Sbjct:   44 EKSHNFKVVHTFRGPHWCEYCANFMWGLIAQGVKCSALDCGLNVHKQCCRLVPTDCQPDPRRLPKVFGCDLTALVKAHRGRLPMVVEMCIGEIEARGLKSEGLYRVSGVSDLVEEVRTAFDK 165

[Close]

BLAST of N-chimaerin vs. Ensembl Sea Lamprey
Match: chn2 (chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5])

HSP 1 Score: 89.7373 bits (221), Expect = 1.668e-20
Identity = 39/84 (46.43%), Postives = 57/84 (67.86%), Query Frame = 3

Query: 1263 DCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            DCG   H++CS  VP DC PD+K +K+V+  +LT+L K   R  PM++   ++E+E RG+  EG+YRVSG SE I++VK   D+
Sbjct:    2 DCGLNVHKQCSKVVPHDCEPDLKHVKKVYSCDLTTLVKAHNRKRPMVVDMCIKEIEMRGLRSEGLYRVSGFSEHIEDVKMAFDR 85

[Close]

BLAST of N-chimaerin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009964.1 (pep scaffold:Pmarinus_7.0:GL476672:413959:431811:1 gene:ENSPMAG00000009003.1 transcript:ENSPMAT00000009964.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.0922 bits (170), Expect = 1.154e-12
Identity = 35/96 (36.46%), Postives = 56/96 (58.33%), Query Frame = 3

Query: 1044 NSLSSDASLDNQLLNDTKSEFSG-----VTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            ++L SD  L  QLL  + S   G     V S S+T ++    Q + H    H++K P +CD+C   +WGLV QG+KC+ CG   H++C+ ++P++C
Sbjct:   20 HNLQSDNIL--QLLTPSDSVQEGDLIEVVLSASATLEDI---QIRPHALFVHSYKSPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNC 110

HSP 2 Score: 57.3806 bits (137), Expect = 9.566e-9
Identity = 22/53 (41.51%), Postives = 33/53 (62.26%), Query Frame = 3

Query: 1167 HNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPD 1325
            H F+  ++  P  C  C   + GL  QGV+C+DC F  H++C+D+V +DCL D
Sbjct:  185 HTFEVRSYTRPTVCQSCKRLLKGLFRQGVQCKDCKFNCHKRCADKVRNDCLGD 237

[Close]

BLAST of N-chimaerin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008732.1 (pep scaffold:Pmarinus_7.0:GL476329:1614832:1658171:1 gene:ENSPMAG00000007889.1 transcript:ENSPMAT00000008732.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.2402 bits (160), Expect = 1.275e-11
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 3

Query: 1167 HNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCL 1319
            H F  H++K P  C FC   + GL  QG++C+DC F  H++C+ +VP DCL
Sbjct:   97 HTFVVHSYKRPTMCQFCKRLLKGLFRQGMQCKDCKFNCHKRCAPKVPKDCL 147

[Close]

BLAST of N-chimaerin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001899.1 (pep scaffold:Pmarinus_7.0:GL483946:1107:7180:-1 gene:ENSPMAG00000001725.1 transcript:ENSPMAT00000001899.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 1.625e-11
Identity = 28/61 (45.90%), Postives = 41/61 (67.21%), Query Frame = 3

Query:  318 KFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            +F   T+N++LFYD   G+H+VG K F+ I+DLV DG I LY+E++ A  + R+    IYE
Sbjct:    1 RFGNQTRNFRLFYD---GKHFVGEKRFESIHDLVTDGFITLYVETKAAEYIARMTINPIYE 58

[Close]

BLAST of N-chimaerin vs. Ensembl Yeast
Match: BEM2 (Rho GTPase activating protein (RhoGAP); involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence; potential GAP for Rho4p [Source:SGD;Acc:S000000957])

HSP 1 Score: 47.7506 bits (112), Expect = 6.678e-6
Identity = 19/58 (32.76%), Postives = 38/58 (65.52%), Query Frame = 3

Query: 1341 RVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            ++FG+ L  + + E   +P I+++L+EE+E RG++  G+YR+ G+   I+ +K   D+
Sbjct: 1963 KIFGVPLEDVCERENTLIPTIVVKLLEEIELRGLDEVGLYRIPGSIGSINALKNAFDE 2020

[Close]

BLAST of N-chimaerin vs. Ensembl Nematostella
Match: EDO42176 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S254])

HSP 1 Score: 154.066 bits (388), Expect = 2.470e-40
Identity = 63/118 (53.39%), Postives = 87/118 (73.73%), Query Frame = 3

Query: 1161 KQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            K HNFKT+TFKGPHWCD C +F+WGL  QGVKCQDCGF AH++C+  +P++C PD K +KR FG++LT+L K+     P ++   + EVE RG++ EG+YRVSG ++ I+ +K   DK
Sbjct:  191 KAHNFKTNTFKGPHWCDHCRNFLWGLTMQGVKCQDCGFNAHKQCTKAIPNNCKPDKKYIKRAFGVDLTTLVKLHNTKRPFVVDICINEVEKRGLDSEGLYRVSGFADDIEALKNSFDK 308

HSP 2 Score: 97.0561 bits (240), Expect = 3.169e-21
Identity = 50/118 (42.37%), Postives = 78/118 (66.10%), Query Frame = 3

Query:   99 VWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIES 452
            VW++ LY+LQQ+AP+   VV  NEV+++       +HG I+R+E + ++  Q  G YL+R+  R    +TL ++FD  TKN++L+YD   G HYVG K F  I++LV DGLI +Y+++
Sbjct:   12 VWKSYLYQLQQKAPQPICVVCNNEVVNRVIAGVTMFHGSISREEADELVSRQD-GCYLVRESQRSPWAYTLTMRFD-GTKNFRLYYD---GMHYVGDKRFQTIHELVADGLITMYMDT 124

[Close]

BLAST of N-chimaerin vs. Ensembl Nematostella
Match: EDO41731 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3I3])

HSP 1 Score: 63.1586 bits (152), Expect = 6.956e-11
Identity = 21/53 (39.62%), Postives = 31/53 (58.49%), Query Frame = 3

Query: 1161 KQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCL 1319
            + H+F   + + P WCD C  F+WGL  Q ++C+ C +  HR+C   V  DCL
Sbjct:    2 RGHSFLPFSLRNPTWCDLCGEFIWGLYKQAIRCKHCKYTCHRRCRIDVDLDCL 54

[Close]

BLAST of N-chimaerin vs. Ensembl Nematostella
Match: EDO41241 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z5])

HSP 1 Score: 64.6994 bits (156), Expect = 1.054e-10
Identity = 23/54 (42.59%), Postives = 33/54 (61.11%), Query Frame = 3

Query: 1167 HNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDM 1328
            H F  H++K P  C  C   + GL  QG +C+DC F  HRKC+++ P +CL D+
Sbjct:  217 HTFAVHSYKKPTMCQICKRLLRGLFRQGFQCKDCKFNCHRKCAEKAPKNCLGDV 270

HSP 2 Score: 62.3882 bits (150), Expect = 5.458e-10
Identity = 21/52 (40.38%), Postives = 34/52 (65.38%), Query Frame = 3

Query: 1161 KQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC 1316
            + H    H++K P +CDFC   ++GLV QG+KC  CG   H++C+ R+ ++C
Sbjct:   99 RSHQLAVHSYKSPTFCDFCGQMLYGLVRQGLKCDGCGGNFHKRCAYRIRNNC 150

[Close]

BLAST of N-chimaerin vs. Ensembl Nematostella
Match: EDO48213 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKA6])

HSP 1 Score: 64.3142 bits (155), Expect = 1.109e-10
Identity = 45/147 (30.61%), Postives = 73/147 (49.66%), Query Frame = 3

Query: 1179 THTFK---GPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDC-LPDMKRLKRVFGIELTS-LGKVEKRG--VPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDAVLSD-SNVTAHSNAKTLEM 1595
            TH FK    P  C  C  +++     G +C+ CG   H++C  R+ + C   +  R    FG++    L   +K+G  VP I+   ++E+  RG+ ++GIYRVSG       VK+ ++K+   +   A L D S V  H  A  L++
Sbjct:  517 THQFKKLRAPSRCRDCDSYVY---FNGAECEQCGLTCHKRCLARLTNKCSYKNRTRRMTTFGVDFYHHLLATDKQGECVPYIVSSCIKEINNRGLHVKGIYRVSG-------VKSRVEKLCQAFENGAELVDLSTVPPHVIAAVLKL 653

[Close]

BLAST of N-chimaerin vs. Ensembl Nematostella
Match: EDO32050 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW72])

HSP 1 Score: 61.6178 bits (148), Expect = 7.800e-10
Identity = 22/51 (43.14%), Postives = 34/51 (66.67%), Query Frame = 3

Query: 1167 HNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCL 1319
            HNF++ + + P +C  C   +WGL  QG+KC+DCG + H +C D + +DCL
Sbjct:   45 HNFESFSTQVPAYCYECEGLLWGLAWQGLKCRDCGVKCHERCKDLLNADCL 95

[Close]

BLAST of N-chimaerin vs. Ensembl Medaka
Match: ENSORLT00000038663.1 (N-chimaerin [Source:NCBI gene;Acc:101159729])

HSP 1 Score: 164.851 bits (416), Expect = 1.179e-43
Identity = 76/183 (41.53%), Postives = 117/183 (63.93%), Query Frame = 3

Query: 1008 EESGYTVSTTDTNSLSSDASLDNQL------------LNDTKSE-FSGVTSKSSTNQNCYAEQ-EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            E  GYT       +L+ + +L NQ+             ND  +E  + +  +++  ++  A + EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD++ +K+V+  +LT+L K      PM++   ++E+EARG++ EG+YR+SG SELI++VK   D+
Sbjct:  148 EHVGYT-------TLNQEPTLKNQVQRCPDEPDAARGRNDCSTERLTSLVRRATLRESDLAPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKVVPNDCQPDLRHVKKVYSCDLTTLVKAHNTKRPMVVDMCIQEIEARGLQSEGLYRISGFSELIEDVKLAFDR 323

HSP 2 Score: 128.257 bits (321), Expect = 3.703e-31
Identity = 64/151 (42.38%), Postives = 102/151 (67.55%), Query Frame = 3

Query:   48 VRVIYNI*FRFMEYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            +R+  N+ F   +Y   VW++ LY+LQQ+AP  + V   +EV ++P YYG E+HG I+R+E + ++ +Q  G+YLIR+  R  GT+TL ++F   T+N++L++D   G+H+VG K F+ I+DLV DGLI LYIE++ A  + ++    IYE
Sbjct:    3 IRMALNV-FDHDDYRPPVWKSYLYQLQQEAPHPRRVTCTSEVENRPKYYGREFHGMISREETDQLL-SQAEGSYLIRESQRQPGTYTLALRFGNQTRNFRLYHD---GKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYE 148

[Close]

BLAST of N-chimaerin vs. Ensembl Medaka
Match: chn2 (chimerin 2 [Source:NCBI gene;Acc:101156676])

HSP 1 Score: 164.466 bits (415), Expect = 1.836e-43
Identity = 70/138 (50.72%), Postives = 97/138 (70.29%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDA-VLSDSNVTA 1568
            EK HNFK HTF+GPHWC++C +FMWGL+AQGV+C DCG   H++CS  VPSDC PD++R+K+VF  +LT+L K      PM++   + E+E RGM+ EG+YRVSG SE I++V+   D+   +  I A   +D N+ A
Sbjct:  209 EKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKLVPSDCQPDLRRIKKVFSCDLTTLVKAHNTMRPMVVDMCIREIELRGMKSEGLYRVSGFSEHIEDVRLSFDRDGEKVDISASAYADINIIA 346

HSP 2 Score: 124.02 bits (310), Expect = 1.275e-29
Identity = 61/139 (43.88%), Postives = 91/139 (65.47%), Query Frame = 3

Query:   84 EYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            +Y   +W++ LY+LQQ+AP+ K V    E+ ++P YYG E+HG I R+  + ++ A   GAYLIR+  R  GT TL ++F + T NY+LFYD   G+H+VG K F+ ++DLV D LI LYIE++ A  + ++    IYE
Sbjct:   20 DYQPPIWKSYLYQLQQEAPRPKRVTCPQEMETRPKYYGREFHGMIPREYADQLL-AGVEGAYLIRESQRQPGTHTLALRFGDQTLNYRLFYD---GKHFVGEKRFESVHDLVTDALITLYIETKAAEYIAKMTTNPIYE 154

[Close]

BLAST of N-chimaerin vs. Ensembl Medaka
Match: ENSORLT00000008037.2 (N-chimaerin [Source:NCBI gene;Acc:101159729])

HSP 1 Score: 164.466 bits (415), Expect = 2.030e-43
Identity = 64/119 (53.78%), Postives = 91/119 (76.47%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            EK HNFK HTF+GPHWC++C +FMWGL+AQGVKC DCG   H++CS  VP+DC PD++ +K+V+  +LT+L K      PM++   ++E+EARG++ EG+YR+SG SELI++VK   D+
Sbjct:  216 EKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKVVPNDCQPDLRHVKKVYSCDLTTLVKAHNTKRPMVVDMCIQEIEARGLQSEGLYRISGFSELIEDVKLAFDR 334

HSP 2 Score: 127.102 bits (318), Expect = 1.089e-30
Identity = 61/139 (43.88%), Postives = 96/139 (69.06%), Query Frame = 3

Query:   84 EYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYE 500
            +Y   VW++ LY+LQQ+AP  + V   +EV ++P YYG E+HG I+R+E + ++ +Q  G+YLIR+  R  GT+TL ++F   T+N++L++D   G+H+VG K F+ I+DLV DGLI LYIE++ A  + ++    IYE
Sbjct:   14 DYRPPVWKSYLYQLQQEAPHPRRVTCTSEVENRPKYYGREFHGMISREETDQLL-SQAEGSYLIRESQRQPGTYTLALRFGNQTRNFRLYHD---GKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYE 148

[Close]

BLAST of N-chimaerin vs. Ensembl Medaka
Match: chn1 (chimerin 1 [Source:NCBI gene;Acc:101163213])

HSP 1 Score: 146.747 bits (369), Expect = 3.245e-38
Identity = 57/119 (47.90%), Postives = 84/119 (70.59%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            EK HNFK H F+GPHWC+ C  FMWGL+AQGVKC DCG   H++CS    +DC P+++ +++V+  +LT+L K      PM++   + E+E+RG++ EG+YR+SG S+ ++EVK   DK
Sbjct:   98 EKVHNFKVHNFRGPHWCEHCARFMWGLMAQGVKCTDCGLNFHKECSALAANDCKPNLRNIRKVYSCDLTTLVKAYNTARPMVVDMCIREIESRGLKSEGLYRISGFSDSVEEVKTGFDK 216

[Close]

BLAST of N-chimaerin vs. Ensembl Medaka
Match: chn1 (chimerin 1 [Source:NCBI gene;Acc:101163213])

HSP 1 Score: 72.7886 bits (177), Expect = 1.360e-13
Identity = 25/34 (73.53%), Postives = 28/34 (82.35%), Query Frame = 3

Query: 1158 EKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKC 1259
            EK HNFK H F+GPHWC+ C  FMWGL+AQGVKC
Sbjct:   78 EKVHNFKVHNFRGPHWCEHCARFMWGLMAQGVKC 111

[Close]

BLAST of N-chimaerin vs. Planmine SMEST
Match: SMESG000066507.1 (SMESG000066507.1)

HSP 1 Score: 1010.36 bits (2611), Expect = 0.000e+0
Identity = 478/478 (100.00%), Postives = 478/478 (100.00%), Query Frame = 3

Query:   81 MEYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQMTRQKPVSTKKNHGHSNNREINEKGSPKTSVNSHSYTIKNKDNESIQIVTCQIDTSNIKLNPFYLKEDSKSSNNPFLASGDHIDQYETNICPPIRHSSLISSQLARKKQLQIPSNIPCSDDESVQNYHQSDTSTDRQVDTSSSSSMDTRGETKNSMEESGYTVSTTDTNSLSSDASLDNQLLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            MEYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQMTRQKPVSTKKNHGHSNNREINEKGSPKTSVNSHSYTIKNKDNESIQIVTCQIDTSNIKLNPFYLKEDSKSSNNPFLASGDHIDQYETNICPPIRHSSLISSQLARKKQLQIPSNIPCSDDESVQNYHQSDTSTDRQVDTSSSSSMDTRGETKNSMEESGYTVSTTDTNSLSSDASLDNQLLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK
Sbjct:    1 MEYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQMTRQKPVSTKKNHGHSNNREINEKGSPKTSVNSHSYTIKNKDNESIQIVTCQIDTSNIKLNPFYLKEDSKSSNNPFLASGDHIDQYETNICPPIRHSSLISSQLARKKQLQIPSNIPCSDDESVQNYHQSDTSTDRQVDTSSSSSMDTRGETKNSMEESGYTVSTTDTNSLSSDASLDNQLLNDTKSEFSGVTSKSSTNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 478

[Close]

BLAST of N-chimaerin vs. Planmine SMEST
Match: SMESG000057671.1 (SMESG000057671.1)

HSP 1 Score: 354.755 bits (909), Expect = 2.014e-112
Identity = 198/494 (40.08%), Postives = 289/494 (58.50%), Query Frame = 3

Query:   81 MEYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDEVENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHYVGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYYTLQMTRQKPVSTKKNHGHSNNREINEKGSPKTSVNSHSYTIKNKDNESIQIVTCQIDT---SNIKLNPFYL-KEDSKSSNNPFLASGDHIDQYETNICPPIRHSSLISSQLARKKQLQIPSNI---PCSDDESVQNYHQSDTSTDRQVDTSSSSSMDTRGETKNSMEESGYTVSTTDTNSL---SSDASLDNQLLNDTKSEFSGVTSKSST------NQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVEARGMEIEGIYRVSGNSELIDEVKADLDK 1514
            M++  E+W  +LYKLQQQAP    +    ++  +   YG EYHGKI R E ++++     GA+LIRD  R  G FTLVI+FD + KNY L+Y+  T QH+VG KYFD I DLVQDGLIH+YIESRGA  L++IAE  +YE +PF+++R+YT+Q         K  H  S N +  +           +  + N+  ++I+      D+   ++++ +   L K DS +  +P L++    D  E     P R  SL  S   R+K  Q PS I   P S++ ++ +              ++ S  +   + +N++ +   ++S  D+  L   + D S  +   +   S  SG++   S        QN + + EK HNFK HTF GP WCDFC HFMWGLVAQGV+C DCGFQAH+KCSD+V +DC P MKR+KRVFGIELTSL K+E R +P++  +L++ +E R +  +G+YR+SGN +LI+EV+ DL+K
Sbjct:    1 MDFSKEIWHCELYKLQQQAPTPLIIKCNRKLDKRLNQYGEEYHGKIDRIETDDILSKHRNGAFLIRDSQRNAGAFTLVIRFDRTCKNYVLYYNPETKQHFVGSKYFDSILDLVQDGLIHMYIESRGAEILRKIAEAQVYESTPFYQSRFYTIQ-------HEKLQHEQSKNYQRIDPSDLYNQTCVKNKHLTNRIPQNIEDFNGSCDSGIFNSLRSDEGILEKGDSSNEPSPQLSTKTTCDNSEDPPVAPPRRKSLYYS--LRQKNSQRPSLILESPSSNNSTLSS------------QMTTGSHYEQIFDCRNNLLDDSMSISVFDSTELPNNTKDLSQSSPGSDRKSSNRSGLSRILSLRTPVIEQQNSFKQLEKSHNFKQHTFVGPQWCDFCAHFMWGLVAQGVQCFDCGFQAHKKCSDKVAADCFPVMKRMKRVFGIELTSLAKMENRAIPLVFEKLIQALEDRDLNSQGLYRISGNIDLIEEVRIDLNK 473

[Close]

BLAST of N-chimaerin vs. Planmine SMEST
Match: SMESG000042667.1 (SMESG000042667.1)

HSP 1 Score: 64.3142 bits (155), Expect = 3.435e-10
Identity = 23/51 (45.10%), Postives = 32/51 (62.75%), Query Frame = 3

Query: 1167 HNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCL 1319
            HNF+  +   P +C  C   +WGL  QGVKCQ+CG + H KC + + +DCL
Sbjct:  971 HNFQVWSATSPTYCYECEGLLWGLARQGVKCQECGVKCHEKCKELLNADCL 1021

[Close]

BLAST of N-chimaerin vs. Planmine SMEST
Match: SMESG000042667.1 (SMESG000042667.1)

HSP 1 Score: 64.3142 bits (155), Expect = 3.443e-10
Identity = 23/51 (45.10%), Postives = 32/51 (62.75%), Query Frame = 3

Query: 1167 HNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCL 1319
            HNF+  +   P +C  C   +WGL  QGVKCQ+CG + H KC + + +DCL
Sbjct:  965 HNFQVWSATSPTYCYECEGLLWGLARQGVKCQECGVKCHEKCKELLNADCL 1015

[Close]

BLAST of N-chimaerin vs. Planmine SMEST
Match: SMESG000042667.1 (SMESG000042667.1)

HSP 1 Score: 64.3142 bits (155), Expect = 3.552e-10
Identity = 23/51 (45.10%), Postives = 32/51 (62.75%), Query Frame = 3

Query: 1167 HNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQAHRKCSDRVPSDCL 1319
            HNF+  +   P +C  C   +WGL  QGVKCQ+CG + H KC + + +DCL
Sbjct:  965 HNFQVWSATSPTYCYECEGLLWGLARQGVKCQECGVKCHEKCKELLNADCL 1015

The following BLAST results are available for this feature:

BLAST of N-chimaerin vs. Ensembl Human
BLAST of N-chimaerin vs. Ensembl Celegans
BLAST of N-chimaerin vs. Ensembl Fly
BLAST of N-chimaerin vs. Ensembl Zebrafish
BLAST of N-chimaerin vs. Ensembl Xenopus
BLAST of N-chimaerin vs. Ensembl Mouse
BLAST of N-chimaerin vs. UniProt/SwissProt
BLAST of N-chimaerin vs. TrEMBL
BLAST of N-chimaerin vs. Ensembl Cavefish
BLAST of N-chimaerin vs. Ensembl Sea Lamprey
BLAST of N-chimaerin vs. Ensembl Yeast
BLAST of N-chimaerin vs. Ensembl Nematostella
BLAST of N-chimaerin vs. Ensembl Medaka
BLAST of N-chimaerin vs. Planmine SMEST

BLAST of N-chimaerin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CHN2	2.314e-44	47.86	chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944]	[more]
CHN1	4.743e-44	47.14	chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943]	[more]
CHN1	8.386e-44	47.14	chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943]	[more]
CHN2	9.196e-44	47.86	chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944]	[more]
CHN1	1.618e-43	53.78	chimerin 1 [Source:HGNC Symbol;Acc:HGNC:1943]	[more]

BLAST of N-chimaerin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
chin-1	1.624e-37	47.86	CHImaeriN (Rac-GTPase-activating protein) homolog ...	[more]
rsf-1	2.406e-11	36.36	RASSF (Ras-association domain family) homolog [So...	[more]
rsf-1	2.406e-11	36.36	RASSF (Ras-association domain family) homolog [So...	[more]
rsf-1	2.895e-11	36.36	RASSF (Ras-association domain family) homolog [So...	[more]
dkf-2	9.426e-11	42.00	Serine/threonine-protein kinase dkf-2 [Source:Uni...	[more]

BLAST of N-chimaerin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RhoGAP5A	1.526e-41	48.65	gene:FBgn0029778 transcript:FBtr0070784	[more]
RhoGAP5A	2.372e-41	48.65	gene:FBgn0029778 transcript:FBtr0070785	[more]
PKD	5.426e-13	44.23	gene:FBgn0038603 transcript:FBtr0337037	[more]
PKD	5.426e-13	44.23	gene:FBgn0038603 transcript:FBtr0337036	[more]
PKD	2.119e-11	44.23	gene:FBgn0038603 transcript:FBtr0330312	[more]

BLAST of N-chimaerin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
chn1	2.389e-44	53.78	chimerin 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1934]	[more]
chn2	3.922e-43	46.71	chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5]	[more]
chn1	4.349e-43	53.78	chimerin 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1934]	[more]
chn2	5.052e-43	46.71	chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5]	[more]
myo9ab	8.268e-16	33.33	myosin IXAb [Source:NCBI gene;Acc:562199]	[more]

BLAST of N-chimaerin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
edem3	2.660e-44	46.43	ER degradation enhancer, mannosidase alpha-like 3 ...	[more]
edem3	1.314e-43	52.94	ER degradation enhancer, mannosidase alpha-like 3 ...	[more]
edem3	1.582e-43	50.00	ER degradation enhancer, mannosidase alpha-like 3 ...	[more]
edem3	2.855e-43	50.77	ER degradation enhancer, mannosidase alpha-like 3 ...	[more]
edem3	2.994e-43	50.00	ER degradation enhancer, mannosidase alpha-like 3 ...	[more]

BLAST of N-chimaerin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Chn2	2.421e-45	49.26	chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243]	[more]
Chn2	7.256e-45	49.26	chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243]	[more]
Chn2	8.396e-45	49.26	chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243]	[more]
Chn2	1.328e-44	47.86	chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243]	[more]
Chn2	2.696e-44	47.86	chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243]	[more]

BLAST of N-chimaerin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q03070\|CHIO_RAT	7.999e-44	49.26	Beta-chimaerin OS=Rattus norvegicus OX=10116 GN=Ch...	[more]
sp\|Q17QN0\|CHIN_BOVIN	2.218e-43	47.86	N-chimaerin OS=Bos taurus OX=9913 GN=CHN1 PE=2 SV=...	[more]
sp\|Q80XD1\|CHIO_MOUSE	3.848e-43	47.86	Beta-chimaerin OS=Mus musculus OX=10090 GN=Chn2 PE...	[more]
sp\|P30337\|CHIN_RAT	9.893e-43	47.14	N-chimaerin OS=Rattus norvegicus OX=10116 GN=Chn1 ...	[more]
sp\|P52757\|CHIO_HUMAN	2.238e-42	45.51	Beta-chimaerin OS=Homo sapiens OX=9606 GN=CHN2 PE=...	[more]

BLAST of N-chimaerin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5K3ESY6	6.696e-100	37.65	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A0R3X7A1	1.166e-98	38.93	Uncharacterized protein OS=Hydatigena taeniaeformi...	[more]
W6UNW5	9.402e-97	38.29	N-chimaerin OS=Echinococcus granulosus OX=6210 GN=...	[more]
A0A564XWJ9	1.084e-93	36.48	Uncharacterized protein OS=Hymenolepis diminuta OX...	[more]
A0A3P6GMB0	6.679e-85	37.36	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]

BLAST of N-chimaerin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
chn1	7.829e-44	48.55	chimerin 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1934]	[more]
myo9aa	1.502e-14	31.71	myosin IXAa [Source:NCBI gene;Acc:100006612]	[more]
gmip	3.692e-13	27.92	GEM interacting protein [Source:NCBI gene;Acc:1030...	[more]
gmip	3.965e-13	26.90	GEM interacting protein [Source:NCBI gene;Acc:1030...	[more]
gmip	4.166e-13	26.90	GEM interacting protein [Source:NCBI gene;Acc:1030...	[more]

BLAST of N-chimaerin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
chn2	2.901e-43	54.10	chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5]	[more]
chn2	1.668e-20	46.43	chimerin 2 [Source:ZFIN;Acc:ZDB-GENE-091020-5]	[more]
ENSPMAT00000009964.1	1.154e-12	36.46	pep scaffold:Pmarinus_7.0:GL476672:413959:431811:1...	[more]
ENSPMAT00000008732.1	1.275e-11	45.10	pep scaffold:Pmarinus_7.0:GL476329:1614832:1658171...	[more]
ENSPMAT00000001899.1	1.625e-11	45.90	pep scaffold:Pmarinus_7.0:GL483946:1107:7180:-1 ge...	[more]

BLAST of N-chimaerin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
BEM2	6.678e-6	32.76	Rho GTPase activating protein (RhoGAP); involved i...	[more]

BLAST of N-chimaerin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO42176	2.470e-40	53.39	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41731	6.956e-11	39.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41241	1.054e-10	42.59	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48213	1.109e-10	30.61	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32050	7.800e-10	43.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of N-chimaerin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000038663.1	1.179e-43	41.53	N-chimaerin [Source:NCBI gene;Acc:101159729]	[more]
chn2	1.836e-43	50.72	chimerin 2 [Source:NCBI gene;Acc:101156676]	[more]
ENSORLT00000008037.2	2.030e-43	53.78	N-chimaerin [Source:NCBI gene;Acc:101159729]	[more]
chn1	3.245e-38	47.90	chimerin 1 [Source:NCBI gene;Acc:101163213]	[more]
chn1	1.360e-13	73.53	chimerin 1 [Source:NCBI gene;Acc:101163213]	[more]

BLAST of N-chimaerin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000066507.1	0.000e+0	100.00	SMESG000066507.1	[more]
SMESG000057671.1	2.014e-112	40.08	SMESG000057671.1	[more]
SMESG000042667.1	3.435e-10	45.10	SMESG000042667.1	[more]
SMESG000042667.1	3.443e-10	45.10	SMESG000042667.1	[more]
SMESG000042667.1	3.552e-10	45.10	SMESG000042667.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30005615 ID=SMED30005615|Name=N-chimaerin|organism=Schmidtea mediterranea sexual|type=transcript|length=2272bp
TATGAAACAATTTAATTATTTAAGTGGTTAAGAATGGATATTATTTAGTT
AGAGTTATTTATAATATTTAATTTAGATTTATGGAATATATAAATGAAGT
TTGGCGCACAGATTTATATAAATTACAACAGCAAGCTCCAAAAGCAAAGC
CTGTAGTTAATAAAAATGAAGTTTTATCAAAGCCTGCTTATTATGGAGTA
GAATATCATGGAAAAATAACTCGAGATGAAGTTGAAAATGTTATGAGAGC
CCAACCAGCAGGGGCTTATCTAATAAGAGATGGATTGAGATGTCGTGGAA
CTTTCACATTAGTTATTAAATTTGATGAATCAACTAAAAATTACAAACTA
TTCTACGATTTTAATACCGGTCAACATTATGTGGGGTACAAATACTTTGA
TAAAATCAATGATTTGGTTCAAGATGGACTTATTCATTTGTATATTGAAT
CTAGAGGAGCTGCAGAATTAAAAAGAATCGCAGAATGTAATATATATGAA
GATTCGCCGTTTTTCAAAGCTCGTTACTATACTCTGCAAATGACAAGGCA
GAAACCAGTCTCAACAAAAAAAAACCATGGTCATTCAAATAATCGGGAAA
TTAATGAAAAAGGTTCACCAAAGACATCAGTAAATTCTCATTCGTATACA
ATTAAAAATAAAGACAATGAATCAATTCAAATTGTCACTTGCCAAATCGA
CACTAGCAATATTAAATTAAATCCTTTTTATTTGAAAGAAGATTCCAAAT
CTTCAAATAATCCATTTCTGGCTTCTGGAGATCATATTGACCAATATGAG
ACTAATATCTGCCCACCTATTCGACACTCATCACTGATAAGCTCTCAGCT
TGCCCGCAAAAAACAATTGCAAATTCCTTCTAATATACCTTGTTCTGATG
ACGAATCAGTACAGAACTATCATCAGTCTGATACAAGTACAGATCGTCAA
GTAGATACGTCTTCATCTTCATCCATGGACACAAGAGGAGAAACCAAAAA
TTCAATGGAAGAATCTGGCTATACAGTTAGCACAACGGATACAAATTCTT
TATCCAGTGATGCATCTTTGGATAATCAACTTTTGAATGATACGAAATCT
GAGTTTTCTGGTGTTACATCAAAATCTTCAACTAATCAAAATTGCTATGC
TGAACAAGAGAAGCAACATAATTTTAAAACACATACTTTCAAAGGTCCTC
ATTGGTGTGATTTTTGCACTCACTTTATGTGGGGTCTTGTAGCTCAGGGT
GTCAAATGTCAGGATTGTGGTTTCCAGGCTCATCGAAAATGCTCAGATAG
AGTTCCTTCAGATTGTTTACCAGATATGAAAAGATTGAAAAGAGTATTTG
GTATTGAATTGACAAGCTTAGGTAAAGTTGAAAAACGAGGTGTTCCAATG
ATTATCATGAGATTGGTAGAAGAGGTTGAAGCTCGTGGTATGGAAATTGA
AGGTATCTACCGAGTTTCGGGAAATTCCGAATTAATAGATGAAGTAAAGG
CAGATTTAGATAAAGTGAAGCTCCGGTGGGCCATTGACGCAGTCTTGTCT
GATTCAAATGTCACAGCACACAGCAACGCTAAAACTTTGGAGATGACAGA
TGACAACTTGAATCTAGCTGAAGCTATCATACTCCTTTTGAAACCTTTGA
AACAAATGTTCATTGTCCTGAGAAATCTAGAAGCATCAAAACCGAATGAC
AGTGCCACCATCCAACAGTGTCGACGCACCATCGGCGCCCAATTATGCCA
ACGTTACTACTCCACTGGATTTAACACACTGAATGGACCCAAGGCCACCG
TGTTTGACCCACGTTACAAACTGTTAAAAAAAATTTCGGAAGAGTCTCGA
CTTGAAACATACGCGGTAGTGCGATCGGAATTAGAAATTATTGGTGCCAA
CACTGCGGAGGAAGCAGATGCAGCAGAACCAACTCCAAAGAAAGCCAGAG
TCGAAAACGAAAATATTTTTGATGACCTTGCTGCTCTGTGTCCCATTCAA
TGTTATGAATTAGCTAGATACCTGGCCGAGACACCTATGTCGATGAACGT
AGATATTTTACTGTTTTGGCGCGACAACACGAAACGGTTTAAAAAACTAT
CTACTCTGGCACGGAAATATTTGTGTGTACCGTATCATTTTCGTCAGAAT
GTGTATTCTCAATAGCTGGTCACATAGTGAATCGTCGATGATCATCTCTG
GCACCTGACACGGTCGATATGCTTGTTTTTCTCAAACGCAACTGTGCTTT
ATGCTTTGAAAAGTAACTTGAA

protein sequence of SMED30005615-orf-1

>SMED30005615-orf-1 ID=SMED30005615-orf-1|Name=SMED30005615-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=695bp
MEYINEVWRTDLYKLQQQAPKAKPVVNKNEVLSKPAYYGVEYHGKITRDE
VENVMRAQPAGAYLIRDGLRCRGTFTLVIKFDESTKNYKLFYDFNTGQHY
VGYKYFDKINDLVQDGLIHLYIESRGAAELKRIAECNIYEDSPFFKARYY
TLQMTRQKPVSTKKNHGHSNNREINEKGSPKTSVNSHSYTIKNKDNESIQ
IVTCQIDTSNIKLNPFYLKEDSKSSNNPFLASGDHIDQYETNICPPIRHS
SLISSQLARKKQLQIPSNIPCSDDESVQNYHQSDTSTDRQVDTSSSSSMD
TRGETKNSMEESGYTVSTTDTNSLSSDASLDNQLLNDTKSEFSGVTSKSS
TNQNCYAEQEKQHNFKTHTFKGPHWCDFCTHFMWGLVAQGVKCQDCGFQA
HRKCSDRVPSDCLPDMKRLKRVFGIELTSLGKVEKRGVPMIIMRLVEEVE
ARGMEIEGIYRVSGNSELIDEVKADLDKVKLRWAIDAVLSDSNVTAHSNA
KTLEMTDDNLNLAEAIILLLKPLKQMFIVLRNLEASKPNDSATIQQCRRT
IGAQLCQRYYSTGFNTLNGPKATVFDPRYKLLKKISEESRLETYAVVRSE
LEIIGANTAEEADAAEPTPKKARVENENIFDDLAALCPIQCYELARYLAE
TPMSMNVDILLFWRDNTKRFKKLSTLARKYLCVPYHFRQNVYSQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036860	SH2_dom_sf
IPR020454	DAG/PE-bd
IPR000980	SH2
IPR002219	PE/DAG-bd
IPR000198	RhoGAP_dom
IPR008906	HATC_C_dom
IPR012337	RNaseH-like_sf
IPR008936	Rho_GTPase_activation_prot

Vocabulary: **biological process**
Term	Definition
GO:0035556	intracellular signal transduction
GO:0007165	signal transduction

Vocabulary: **molecular function**
Term	Definition
GO:0046983	protein dimerization activity
GO:0003676	nucleic acid binding
GO:0046872	metal ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0005622	intracellular

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR020454	Diacylglycerol/phorbol-ester binding	PRINTS	PR00008	DAGPEDOMAIN	coord: 360..374 score: 33.07 coord: 376..385 score: 47.52 coord: 389..400 score: 44.64 coord: 401..413 score: 40.14
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	SMART	SM00109	c1_12	coord: 363..412 e-value: 9.6E-15 score: 65.0
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	PFAM	PF00130	C1_1	coord: 363..412 e-value: 9.7E-13 score: 47.8
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	PROSITE	PS00479	ZF_DAG_PE_1	coord: 363..412
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	PROSITE	PS50081	ZF_DAG_PE_2	coord: 362..412 score: 15.411
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	CDD	cd00029	C1	coord: 363..412 e-value: 1.6066E-18 score: 77.5323
IPR000980	SH2 domain	SMART	SM00252	SH2_5	coord: 39..122 e-value: 1.3E-7 score: 41.3
IPR000980	SH2 domain	PFAM	PF00017	SH2	coord: 42..114 e-value: 1.1E-10 score: 41.4
IPR000980	SH2 domain	PROSITE	PS50001	SH2	coord: 41..114 score: 11.042
IPR000198	Rho GTPase-activating protein domain	PFAM	PF00620	RhoGAP	coord: 439..490 e-value: 2.9E-8 score: 33.7
IPR000198	Rho GTPase-activating protein domain	PROSITE	PS50238	RHOGAP	coord: 425..637 score: 10.392
IPR008906	HAT, C-terminal dimerisation domain	PFAM	PF05699	Dimer_Tnp_hAT	coord: 643..684 e-value: 4.0E-6 score: 26.5
IPR008936	Rho GTPase activation protein	GENE3D	G3DSA:1.10.555.10		coord: 424..510 e-value: 1.0E-14 score: 56.3
IPR008936	Rho GTPase activation protein	SUPERFAMILY	SSF48350	GTPase activation domain, GAP	coord: 421..484
IPR036860	SH2 domain superfamily	GENE3D	G3DSA:3.30.505.10		coord: 19..126 e-value: 1.5E-20 score: 74.7
IPR036860	SH2 domain superfamily	SUPERFAMILY	SSF55550	SH2 domain	coord: 33..124
None	No IPR available	GENE3D	G3DSA:3.30.60.20		coord: 358..423 e-value: 4.6E-24 score: 86.0
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 158..185
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 266..328
None	No IPR available	PANTHER	PTHR46075:SF2	RHO GTPASE ACTIVATING PROTEIN AT 5A, ISOFORM A	coord: 320..485 coord: 4..171
None	No IPR available	PANTHER	PTHR46075	FAMILY NOT NAMED	coord: 4..171 coord: 320..485
None	No IPR available	SUPERFAMILY	SSF57889	Cysteine-rich domain	coord: 361..417
IPR012337	Ribonuclease H-like superfamily	SUPERFAMILY	SSF53098	Ribonuclease H-like	coord: 479..685