Polycomb group ring finger 2

Overview
NamePolycomb group ring finger 2
Smed IDSMED30005538
Length (bp)824
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Polycomb group ring finger 2 (SMED30005538) t-SNE clustered cells

Violin plots show distribution of expression levels for Polycomb group ring finger 2 (SMED30005538) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Polycomb group ring finger 2 (SMED30005538) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Polycomb group ring finger 2 (SMED30005538) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005538

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30005538SMESG000066343.1 SMESG000066342.1 SMESG000066340.1 dd_Smed_v4_1858_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Human
Match: PCGF2 (polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929])

HSP 1 Score: 117.087 bits (292), Expect = 3.686e-30
Identity = 77/237 (32.49%), Postives = 113/237 (47.68%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENG---------IFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     + K                         K  +ENG          FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGARDRDEK-------------------------KGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEVLYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Human
Match: PCGF2 (polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929])

HSP 1 Score: 117.087 bits (292), Expect = 3.686e-30
Identity = 77/237 (32.49%), Postives = 113/237 (47.68%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENG---------IFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     + K                         K  +ENG          FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGARDRDEK-------------------------KGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEVLYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Human
Match: PCGF2 (polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929])

HSP 1 Score: 117.087 bits (292), Expect = 3.686e-30
Identity = 77/237 (32.49%), Postives = 113/237 (47.68%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENG---------IFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     + K                         K  +ENG          FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGARDRDEK-------------------------KGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEVLYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Human
Match: PCGF2 (polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929])

HSP 1 Score: 117.087 bits (292), Expect = 3.686e-30
Identity = 77/237 (32.49%), Postives = 113/237 (47.68%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENG---------IFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     + K                         K  +ENG          FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGARDRDEK-------------------------KGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEVLYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Human
Match: PCGF2 (polycomb group ring finger 2 [Source:HGNC Symbol;Acc:HGNC:12929])

HSP 1 Score: 117.087 bits (292), Expect = 3.686e-30
Identity = 77/237 (32.49%), Postives = 113/237 (47.68%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENG---------IFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     + K                         K  +ENG          FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGARDRDEK-------------------------KGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEVLYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Celegans
Match: mig-32 (pep chromosome:WBcel235:IV:12089247:12092213:-1 gene:WBGene00008684.1 transcript:F11A10.3a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mig-32)

HSP 1 Score: 62.7734 bits (151), Expect = 6.013e-11
Identity = 25/56 (44.64%), Postives = 33/56 (58.93%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEH-NRYCPLCQCLI 219
            K  + VLN  + C +C GY++D T +  C+HTFCKSC+  Y E  N  CP C   I
Sbjct:  317 KYNMEVLNPFITCGICDGYIVDATTIIDCMHTFCKSCLLTYFESDNNTCPTCGTFI 372
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Celegans
Match: mig-32 (pep chromosome:WBcel235:IV:12089286:12092213:-1 gene:WBGene00008684.1 transcript:F11A10.3a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mig-32)

HSP 1 Score: 62.7734 bits (151), Expect = 6.013e-11
Identity = 25/56 (44.64%), Postives = 33/56 (58.93%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEH-NRYCPLCQCLI 219
            K  + VLN  + C +C GY++D T +  C+HTFCKSC+  Y E  N  CP C   I
Sbjct:  317 KYNMEVLNPFITCGICDGYIVDATTIIDCMHTFCKSCLLTYFESDNNTCPTCGTFI 372
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Fly
Match: l(3)73Ah (gene:FBgn0002283 transcript:FBtr0307336)

HSP 1 Score: 92.0485 bits (227), Expect = 3.835e-22
Identity = 42/101 (41.58%), Postives = 63/101 (62.38%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETR-MGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL 351
             +VKL  +N H+ C +CGGY ID T +T+CLHTFCKSC+ K+LE  + CP C  +I ++  +  +S   D  +Q  +YKLVP L + E +    FY++  +
Sbjct:    3 RRVKLKTINPHITCKICGGYFIDATTVTECLHTFCKSCLVKHLEEKKTCPTCDNIIHQSHPLQYISF--DRTMQDIVYKLVPKLQEDESRRERDFYKSRNM 101
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Fly
Match: l(3)73Ah (gene:FBgn0002283 transcript:FBtr0075311)

HSP 1 Score: 92.0485 bits (227), Expect = 3.835e-22
Identity = 42/101 (41.58%), Postives = 63/101 (62.38%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETR-MGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL 351
             +VKL  +N H+ C +CGGY ID T +T+CLHTFCKSC+ K+LE  + CP C  +I ++  +  +S   D  +Q  +YKLVP L + E +    FY++  +
Sbjct:    3 RRVKLKTINPHITCKICGGYFIDATTVTECLHTFCKSCLVKHLEEKKTCPTCDNIIHQSHPLQYISF--DRTMQDIVYKLVPKLQEDESRRERDFYKSRNM 101
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Fly
Match: Psc (gene:FBgn0005624 transcript:FBtr0087798)

HSP 1 Score: 93.9745 bits (232), Expect = 2.631e-21
Identity = 40/95 (42.11%), Postives = 59/95 (62.11%), Query Frame = 1 
Query:   58 VKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQN 342
            V L+ +N H+IC LC GYLI+ T + +CLH+FC SC+  +L   R+CP C+ +I      K ++K D  LQ  +YKLVP L + E+     FY++
Sbjct:  252 VLLTAVNPHIICHLCQGYLINATTIVECLHSFCHSCLINHLRKERFCPRCEMVINN---AKPNIKSDTTLQAIVYKLVPGLYERELMRKRAFYKD 343
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Fly
Match: Psc (gene:FBgn0005624 transcript:FBtr0345196)

HSP 1 Score: 93.9745 bits (232), Expect = 2.631e-21
Identity = 40/95 (42.11%), Postives = 59/95 (62.11%), Query Frame = 1 
Query:   58 VKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQN 342
            V L+ +N H+IC LC GYLI+ T + +CLH+FC SC+  +L   R+CP C+ +I      K ++K D  LQ  +YKLVP L + E+     FY++
Sbjct:  252 VLLTAVNPHIICHLCQGYLINATTIVECLHSFCHSCLINHLRKERFCPRCEMVINN---AKPNIKSDTTLQAIVYKLVPGLYERELMRKRAFYKD 343
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Fly
Match: Psc (gene:FBgn0005624 transcript:FBtr0345375)

HSP 1 Score: 93.9745 bits (232), Expect = 2.631e-21
Identity = 40/95 (42.11%), Postives = 59/95 (62.11%), Query Frame = 1 
Query:   58 VKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQN 342
            V L+ +N H+IC LC GYLI+ T + +CLH+FC SC+  +L   R+CP C+ +I      K ++K D  LQ  +YKLVP L + E+     FY++
Sbjct:  252 VLLTAVNPHIICHLCQGYLINATTIVECLHSFCHSCLINHLRKERFCPRCEMVINN---AKPNIKSDTTLQAIVYKLVPGLYERELMRKRAFYKD 343
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Zebrafish
Match: pcgf1 (polycomb group ring finger 1 [Source:NCBI gene;Acc:368900])

HSP 1 Score: 108.227 bits (269), Expect = 7.354e-28
Identity = 51/101 (50.50%), Postives = 70/101 (69.31%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNE 357
            K+K+  LN H++C LC GY ID T +T+CLHTFCKSCI KYL+ ++YCP+C   I ET+   ++LK D ++Q  +YKLVP L +SE + I  FYQ+  L  
Sbjct:   16 KIKIKDLNEHIVCYLCAGYFIDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQ-PLLNLKLDRVMQDIVYKLVPGLQESEDKRIKEFYQSRGLER 115
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Zebrafish
Match: pcgf1 (polycomb group ring finger 1 [Source:NCBI gene;Acc:368900])

HSP 1 Score: 108.997 bits (271), Expect = 1.024e-27
Identity = 52/106 (49.06%), Postives = 71/106 (66.98%), Query Frame = 1 
Query:   40 NNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNE 357
            N    K+K+  LN H++C LC GY ID T +T+CLHTFCKSCI KYL+ ++YCP+C   I ET+   ++LK D ++Q  +YKLVP L +SE + I  FYQ+  L  
Sbjct:   62 NEEEVKIKIKDLNEHIVCYLCAGYFIDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQ-PLLNLKLDRVMQDIVYKLVPGLQESEDKRIKEFYQSRGLER 166
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Zebrafish
Match: bmi1a (bmi1 polycomb ring finger oncogene 1a [Source:NCBI gene;Acc:321505])

HSP 1 Score: 105.145 bits (261), Expect = 5.386e-26
Identity = 65/228 (28.51%), Postives = 110/228 (48.25%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEE-------LNENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENGIFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+C LCGGY ID T + +CLH+FCK CI +YLE ++YCP+C   + +T+   ++++ D  LQ  +YKLVP L K+EM+    FY            NE+   V+  +K  +  ++        +  +   +                      T    K  + N  +L C   + V  ++K + +K  + P  Y   + Y D+ L   YTL +I ++
Sbjct:    7 TRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKMCIVRYLETSKYCPICDVQVHKTK-PLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAEHPSVDAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDHRAQQQG--------------------CTEERQKEEVNNKRYLQCPAAMTVMHLRKFLRSKMDIPP-TYQIEVMYEDEPLKDYYTLMDIAYI 212
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Zebrafish
Match: bmi1a (bmi1 polycomb ring finger oncogene 1a [Source:NCBI gene;Acc:321505])

HSP 1 Score: 105.145 bits (261), Expect = 5.386e-26
Identity = 65/228 (28.51%), Postives = 110/228 (48.25%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEE-------LNENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENGIFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+C LCGGY ID T + +CLH+FCK CI +YLE ++YCP+C   + +T+   ++++ D  LQ  +YKLVP L K+EM+    FY            NE+   V+  +K  +  ++        +  +   +                      T    K  + N  +L C   + V  ++K + +K  + P  Y   + Y D+ L   YTL +I ++
Sbjct:    7 TRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKMCIVRYLETSKYCPICDVQVHKTK-PLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAEHPSVDAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDHRAQQQG--------------------CTEERQKEEVNNKRYLQCPAAMTVMHLRKFLRSKMDIPP-TYQIEVMYEDEPLKDYYTLMDIAYI 212
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Zebrafish
Match: bmi1b (bmi1 polycomb ring finger oncogene 1b [Source:NCBI gene;Acc:394249])

HSP 1 Score: 104.76 bits (260), Expect = 7.723e-26
Identity = 48/114 (42.11%), Postives = 73/114 (64.04%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL------NENEFNVS 375
            +++K++ LN HL+C LCGGY ID T + +CLH+FCK CI +YLE ++YCP+C   + +T+   ++++ D  LQ  +YKLVP L K+EM+    FY    +      NE+   VS
Sbjct:    5 TRIKITELNPHLMCVLCGGYFIDATTIVECLHSFCKMCIVRYLETSKYCPICDVQVHKTKP-LLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAEHPVDATNGSNEDRGEVS 117
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Xenopus
Match: qprt (quinolinate phosphoribosyltransferase [Source:Xenbase;Acc:XB-GENE-5897181])

HSP 1 Score: 108.997 bits (271), Expect = 2.047e-27
Identity = 64/221 (28.96%), Postives = 112/221 (50.68%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENGIFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+C LCGGY ID T + +CLH+FCK+CI +YLE ++YCP+C   + +TR   ++++ D  LQ  +YKLVP L K EM+    FY     + +  N S+ +                 + +V  E+K               + D + N +  +   +  +L C   + V  ++K + +K  + P  +   + Y ++ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRP-LLNIRADKTLQDIVYKLVPGLFKGEMKRRRDFYAAHP-SADASNGSNED-----------------RGEVADEDK------------RIITDDEIINPMWPLTANDKRYLRCPAALTVMHLRKFLRSKMDI-PSNFQIDVMYEEEPLKDYYTLMDIAYI 193
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Xenopus
Match: vta1 (vesicle (multivesicular body) trafficking 1 [Source:Xenbase;Acc:XB-GENE-984112])

HSP 1 Score: 107.842 bits (268), Expect = 6.363e-27
Identity = 68/231 (29.44%), Postives = 116/231 (50.22%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVME--NGI-FLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFMNKLEYPDG 738
            ++K++ LN HL+CALCGGY ID   + +CLH+FCK+CI +YLE +++CP+C   + + R   +S++ D  LQ  +YKLVP L + EM+    FY +   +++  +    +K+                    SE+                + D + +L+D   +E  N + FL C   + +  + K + NK  + P +Y   + Y ++ L   YTL +I ++    YP G
Sbjct:    6 RIKMTELNPHLMCALCGGYFIDAATIVECLHSFCKTCILRYLEAHKFCPMCDSQVHKGRP-LLSIRSDKTLQDIVYKLVPGLFRDEMKRRRDFYASYSRSKDSSSAEQGQKVLEAGEAPVQEEENISLSIQFSED----------------ARDEIQDLVDSEDLEKRNSLRFLRCPAAMTITHLAKFLRNKMDV-PSKYKVEILYEEEPLKDYYTLMDIAYI----YPWG 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Xenopus
Match: qprt (quinolinate phosphoribosyltransferase [Source:Xenbase;Acc:XB-GENE-5897181])

HSP 1 Score: 107.457 bits (267), Expect = 8.673e-27
Identity = 45/95 (47.37%), Postives = 67/95 (70.53%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFY 336
            +++K++ LN HL+C LCGGY ID T + +CLH+FCK+CI +YLE ++YCP+C   + +TR   ++++ D  LQ  +YKLVP L K EM+    FY
Sbjct:    5 TRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRP-LLNIRADKTLQDIVYKLVPGLFKGEMKRRRDFY 98
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Xenopus
Match: vta1 (vesicle (multivesicular body) trafficking 1 [Source:Xenbase;Acc:XB-GENE-984112])

HSP 1 Score: 104.375 bits (259), Expect = 1.342e-25
Identity = 43/94 (45.74%), Postives = 65/94 (69.15%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFY 336
            ++K++ LN HL+CALCGGY ID   + +CLH+FCK+CI +YLE +++CP+C   + + R   +S++ D  LQ  +YKLVP L + EM+    FY
Sbjct:    6 RIKMTELNPHLMCALCGGYFIDAATIVECLHSFCKTCILRYLEAHKFCPMCDSQVHKGR-PLLSIRSDKTLQDIVYKLVPGLFRDEMKRRRDFY 98
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Xenopus
Match: pcgf3 (polycomb group ring finger 3 [Source:NCBI gene;Acc:549601])

HSP 1 Score: 97.0561 bits (240), Expect = 1.651e-23
Identity = 45/96 (46.88%), Postives = 63/96 (65.62%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQ 339
             K+KL  +NAH+ C LC GYLID T +T+CLHTFC+SC+ KYLE N  CP C+ +I ++   +  +  D  +Q  +YKLVP L ++EM+    FY 
Sbjct:    4 RKIKLWDINAHITCRLCNGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQY-IGHDRTMQDIVYKLVPGLQEAEMRKQREFYH 98
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Mouse
Match: Pcgf2 (polycomb group ring finger 2 [Source:MGI Symbol;Acc:MGI:99161])

HSP 1 Score: 119.783 bits (299), Expect = 2.919e-31
Identity = 78/229 (34.06%), Postives = 115/229 (50.22%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENGI-FLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     E K +                 LT   D    + G+ FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALGDDEIVSLSIEFYEGVRDREEKKN-----------------LTENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEILYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Mouse
Match: Pcgf2 (polycomb group ring finger 2 [Source:MGI Symbol;Acc:MGI:99161])

HSP 1 Score: 119.783 bits (299), Expect = 2.919e-31
Identity = 78/229 (34.06%), Postives = 115/229 (50.22%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENGI-FLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     E K +                 LT   D    + G+ FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALGDDEIVSLSIEFYEGVRDREEKKN-----------------LTENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEILYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Mouse
Match: Pcgf2 (polycomb group ring finger 2 [Source:MGI Symbol;Acc:MGI:99161])

HSP 1 Score: 119.783 bits (299), Expect = 2.919e-31
Identity = 78/229 (34.06%), Postives = 115/229 (50.22%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENGI-FLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     E K +                 LT   D    + G+ FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALGDDEIVSLSIEFYEGVRDREEKKN-----------------LTENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEILYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Mouse
Match: Pcgf2 (polycomb group ring finger 2 [Source:MGI Symbol;Acc:MGI:99161])

HSP 1 Score: 119.783 bits (299), Expect = 2.919e-31
Identity = 78/229 (34.06%), Postives = 115/229 (50.22%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENGI-FLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     E K +                 LT   D    + G+ FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALGDDEIVSLSIEFYEGVRDREEKKN-----------------LTENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEILYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Mouse
Match: Bmi1 (Bmi1 polycomb ring finger oncogene [Source:MGI Symbol;Acc:MGI:88174])

HSP 1 Score: 107.457 bits (267), Expect = 2.247e-28
Identity = 45/95 (47.37%), Postives = 68/95 (71.58%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFY 336
            +++K++ LN HL+C LCGGY ID T + +CLH+FCK+CI +YLE ++YCP+C   + +TR   ++++ D  LQ  +YKLVP L K+EM+    FY
Sbjct:    5 TRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTR-PLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFY 98
[Close]
BLAST of Polycomb group ring finger 2 vs. UniProt/SwissProt
Match: sp|P23798|PCGF2_MOUSE (Polycomb group RING finger protein 2 OS=Mus musculus OX=10090 GN=Pcgf2 PE=1 SV=2)

HSP 1 Score: 119.783 bits (299), Expect = 2.042e-30
Identity = 78/229 (34.06%), Postives = 115/229 (50.22%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENGI-FLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     E K +                 LT   D    + G+ FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALGDDEIVSLSIEFYEGVRDREEKKN-----------------LTENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEILYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. UniProt/SwissProt
Match: sp|P35227|PCGF2_HUMAN (Polycomb group RING finger protein 2 OS=Homo sapiens OX=9606 GN=PCGF2 PE=1 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.770e-29
Identity = 77/237 (32.49%), Postives = 113/237 (47.68%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL-------NENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENG---------IFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +++K++ LN HL+CALCGGY ID T + +CLH+FCK+CI +YLE N+YCP+C   + +TR   +S++ D  LQ  +YKLVP L K EM+    FY    L       NE+   V   EK  L  ++        Y+     + K                         K  +ENG          FL C   + V  + K + NK  + P +Y   + Y D+ L   YTL +I ++
Sbjct:    5 TRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP-LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGARDRDEK-------------------------KGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDV-PSKYKVEVLYEDEPLKEYYTLMDIAYI 214
[Close]
BLAST of Polycomb group ring finger 2 vs. UniProt/SwissProt
Match: sp|Q4QR06|PCGF1_XENLA (Polycomb group RING finger protein 1 OS=Xenopus laevis OX=8355 GN=pcgf1 PE=2 SV=2)

HSP 1 Score: 109.383 bits (272), Expect = 2.791e-27
Identity = 56/115 (48.70%), Postives = 75/115 (65.22%), Query Frame = 1 
Query:   40 NNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNENEFNVSSVE 384
            N  + KVK+  LN H++C LC GY ID T +T+CLHTFCKSCI KYL+ ++YCPLC   I ET+   ++LK D ++Q  +YKLVP L ++E   I  FY +  L E     S+VE
Sbjct:   28 NEEVVKVKIKELNEHIVCYLCAGYFIDATTITECLHTFCKSCIVKYLQTSKYCPLCNIKIHETQ-PLLNLKLDRVMQDIVYKLVPGLQENEDSRIRDFYHSRGL-ERVLQPSAVE 140
[Close]
BLAST of Polycomb group ring finger 2 vs. UniProt/SwissProt
Match: sp|Q28H21|PCGF1_XENTR (Polycomb group RING finger protein 1 OS=Xenopus tropicalis OX=8364 GN=pcgf1 PE=2 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 4.285e-27
Identity = 56/115 (48.70%), Postives = 75/115 (65.22%), Query Frame = 1 
Query:   40 NNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNENEFNVSSVE 384
            N  + KVK+  LN H++C LC GY ID T +T+CLHTFCKSCI KYL+ ++YCPLC   I ET+   ++LK D ++Q  +YKLVP L ++E   I  FY +  L E     S+VE
Sbjct:   28 NEEVVKVKIKELNEHIVCYLCAGYFIDATTITECLHTFCKSCIVKYLQTSKYCPLCNIKIHETQ-PLLNLKLDRVMQDIVYKLVPGLQENEDGRIRDFYHSRGL-ERVLQPSAVE 140
[Close]
BLAST of Polycomb group ring finger 2 vs. UniProt/SwissProt
Match: sp|Q7ZYZ7|PCGF1_DANRE (Polycomb group RING finger protein 1 OS=Danio rerio OX=7955 GN=pcgf1 PE=3 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 4.761e-27
Identity = 52/106 (49.06%), Postives = 71/106 (66.98%), Query Frame = 1 
Query:   40 NNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNE 357
            N    K+K+  LN H++C LC GY ID T +T+CLHTFCKSCI KYL+ ++YCP+C   I ET+   ++LK D ++Q  +YKLVP L +SE + I  FYQ+  L  
Sbjct:   28 NEEEVKIKIKDLNEHIVCYLCAGYFIDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQ-PLLNLKLDRVMQDIVYKLVPGLQESEDKRIKEFYQSRGLER 132
[Close]
BLAST of Polycomb group ring finger 2 vs. TrEMBL
Match: G7YJ33 (Polycomb group RING finger protein 2 (Fragment) OS=Clonorchis sinensis OX=79923 GN=CLF_109230 PE=4 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 2.485e-37
Identity = 66/119 (55.46%), Postives = 83/119 (69.75%), Query Frame = 1 
Query:   37 MNNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYF---------YQNEELNENEF 366
            M+   + VKLS LN HLIC LCGGYLID T+LT+C+H FC+SCI KYL  ++ CPLCQ LIQETR G  +L+PD +LQ+ +YKLVP LLK+EMQ +  F          QN   +ENE+
Sbjct:    1 MSFTGANVKLSTLNGHLICGLCGGYLIDATVLTECVHVFCRSCIVKYLTEHKVCPLCQSLIQETRPGH-ALRPDTVLQRVVYKLVPGLLKTEMQRLTEFCSSMSASETLQNTRASENEY 118
[Close]
BLAST of Polycomb group ring finger 2 vs. TrEMBL
Match: A0A183W0Y8 (RING-type domain-containing protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS6394 PE=4 SV=1)

HSP 1 Score: 139.043 bits (349), Expect = 6.496e-35
Identity = 61/99 (61.62%), Postives = 78/99 (78.79%), Query Frame = 1 
Query:   37 MNNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYF 333
            M  + S VKLS +N HLIC LCGGYLID T+LT+C+H FC+SCI KYL  N+ CPLCQ L+QETR G+ +L+PD+ LQ+ +YKLVP LLK+EM+ I+ F
Sbjct:    1 MTTSYSGVKLSSINGHLICGLCGGYLIDATVLTECIHVFCRSCILKYLSENKICPLCQSLVQETRPGQ-ALRPDVALQRIVYKLVPGLLKTEMKRISEF 98
[Close]
BLAST of Polycomb group ring finger 2 vs. TrEMBL
Match: A0A075A7N0 (RING-type domain-containing protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=T265_12935 PE=4 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 7.937e-35
Identity = 65/123 (52.85%), Postives = 87/123 (70.73%), Query Frame = 1 
Query:   37 MNNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYF---------YQNEELNENEFNVSS 378
            M+   + VKLS LN HLIC LCGGYLID T+LT+C+H FC+SCI KYL  ++ CPLCQ LIQETR G  +L+PD +LQ+ +YKLVP LLK+EMQ +  F          Q+ + +ENE+++ +
Sbjct:    1 MSFTGANVKLSTLNGHLICGLCGGYLIDATVLTECVHVFCRSCIVKYLTEHKVCPLCQSLIQETRPGH-ALRPDTVLQRVVYKLVPGLLKTEMQRLTEFCSSMSASETMQSTQASENEYSLGT 122
[Close]
BLAST of Polycomb group ring finger 2 vs. TrEMBL
Match: A0A4S2M8E6 (RING-type domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_001950 PE=4 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 1.914e-34
Identity = 64/116 (55.17%), Postives = 83/116 (71.55%), Query Frame = 1 
Query:   37 MNNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNENEFNVSSVE 384
            M+   + VKLS LN HLIC LCGGYLID T+LT+C+H FC+SCI KYL  ++ CPLCQ LIQETR G  +L+PD +LQ+ +YKLVP LLK+EMQ +  F  +   +E   +V + E
Sbjct:    1 MSFTGANVKLSTLNGHLICGLCGGYLIDATVLTECVHVFCRSCIVKYLTEHKVCPLCQSLIQETRPGH-ALRPDTVLQRVVYKLVPGLLKTEMQRLTEFCSSMSASETMQSVHAPE 115
[Close]
BLAST of Polycomb group ring finger 2 vs. TrEMBL
Match: A0A183K3Y2 (RING-type domain-containing protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS9700 PE=4 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 4.366e-33
Identity = 60/99 (60.61%), Postives = 78/99 (78.79%), Query Frame = 1 
Query:   37 MNNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYF 333
            M ++   VKLS +N HLIC LCGGYLID T+LT+C+H FC+SCI KYL  ++ CPLCQ LIQETR G+ +L+PD+ LQ+ +YKLVP LLK+EM+ I+ F
Sbjct:    1 MTSSYPGVKLSSINGHLICGLCGGYLIDATVLTECIHVFCRSCILKYLLEHKICPLCQSLIQETRPGQ-ALRPDVALQRIVYKLVPGLLKTEMKRISEF 98
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Cavefish
Match: pcgf1 (polycomb group ring finger 1 [Source:NCBI gene;Acc:103047474])

HSP 1 Score: 108.612 bits (270), Expect = 4.708e-28
Identity = 52/106 (49.06%), Postives = 71/106 (66.98%), Query Frame = 1 
Query:   40 NNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNE 357
            N    K+K+  LN H++C LC GY ID T +T+CLHTFCKSCI KYL+ ++YCP+C   I ET+   ++LK D ++Q  +YKLVP L +SE + I  FYQ+  L  
Sbjct:   28 NEEEVKIKIKDLNEHIVCYLCAGYFIDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQ-PLLNLKLDRVMQDIVYKLVPGLQESEDKRIREFYQSRGLER 132
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Cavefish
Match: pcgf1 (polycomb group ring finger 1 [Source:NCBI gene;Acc:103047474])

HSP 1 Score: 108.227 bits (269), Expect = 7.143e-28
Identity = 51/101 (50.50%), Postives = 70/101 (69.31%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNE 357
            K+K+  LN H++C LC GY ID T +T+CLHTFCKSCI KYL+ ++YCP+C   I ET+   ++LK D ++Q  +YKLVP L +SE + I  FYQ+  L  
Sbjct:   16 KIKIKDLNEHIVCYLCAGYFIDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQ-PLLNLKLDRVMQDIVYKLVPGLQESEDKRIREFYQSRGLER 115
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Cavefish
Match: bmi1a (BMI1 proto-oncogene, polycomb ring finger [Source:NCBI gene;Acc:103025408])

HSP 1 Score: 104.375 bits (259), Expect = 7.402e-26
Identity = 45/95 (47.37%), Postives = 67/95 (70.53%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFY 336
            +++K++ LN HL+C LCGGY ID T + +CLH+FCK CI +YLE ++YCP+C   + +T+   ++++ D  LQ  +YKLVP L KSEM+    FY
Sbjct:    7 TRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKMCIVRYLETSKYCPICDVQVHKTK-PLLNIRSDKTLQDIVYKLVPGLFKSEMKRRRDFY 100
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Cavefish
Match: bmi1b (polycomb complex protein BMI-1-B-like [Source:NCBI gene;Acc:103034194])

HSP 1 Score: 104.375 bits (259), Expect = 1.094e-25
Identity = 44/95 (46.32%), Postives = 67/95 (70.53%), Query Frame = 1 
Query:   52 SKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFY 336
            +++K++ LN HL+C LCGGY ID T + +CLH+FCK CI +YLE ++YCP+C   + +T+   ++++ D  LQ  +YKLVP L K+EM+    FY
Sbjct:    7 TRIKITELNPHLMCVLCGGYFIDATTIVECLHSFCKMCIVRYLETSKYCPICDVQVHKTKP-LLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFY 100
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Cavefish
Match: PCGF3 (polycomb group ring finger 3 [Source:NCBI gene;Acc:103041260])

HSP 1 Score: 96.2857 bits (238), Expect = 2.331e-23
Identity = 45/95 (47.37%), Postives = 64/95 (67.37%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQ 339
            K+KL  +NAH+ C LC GYLID T +T+CLHTFC+SC+ KYLE N  CP C+ +I ++   +  +  D  +Q  +YKLVP L ++E++    FYQ
Sbjct:   13 KIKLWDINAHITCRLCEGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQY-IGHDRTMQDIVYKLVPGLQEAELRKQRDFYQ 106
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Sea Lamprey
Match: bmi1b (bmi1 polycomb ring finger oncogene 1b [Source:NCBI gene;Acc:394249])

HSP 1 Score: 108.612 bits (270), Expect = 3.821e-29
Identity = 68/224 (30.36%), Postives = 110/224 (49.11%), Query Frame = 1 
Query:   43 NNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKI-VMENG-----IFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTL 696
            +  + ++++ LN HLIC LCGGY ID T +T+CLH+FCK+CI +YLE +++CP+C   + +TR   ++L+ D  LQ  +YKLVP L K EM+    FY      +     SS                   + +V  E+K +       S     +    ++   +  V +NG      +L C   + V  ++K + NK  + PH Y   + + ++ L   YTL
Sbjct:    2 HRTTHIRMTELNPHLICVLCGGYFIDATSITECLHSFCKTCIVRYLESSKFCPVCDVQVHKTR-PLLNLRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAGHPEGDGCKGDSS-----------------EARGEVADEDKQNIADDEIISLSIEYTEGPPSSDKGRSEVKQNGEELRKRYLRCPAAMTVMHLQKFLRNKMEI-PHSYQIEVLHEEESLKDYYTL 206
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Sea Lamprey
Match: pcgf1 (polycomb group ring finger 1 [Source:NCBI gene;Acc:368900])

HSP 1 Score: 104.76 bits (260), Expect = 4.673e-27
Identity = 48/100 (48.00%), Postives = 69/100 (69.00%), Query Frame = 1 
Query:   58 VKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNE 357
            VK+  LN H++C LC GY +D T +T+CLHTFCKSCI KYL+ +++CP+C   I ET+   ++LK D ++Q+ +YKLVP L   E + I  FYQ+  L+ 
Sbjct:   34 VKIKDLNEHIVCILCAGYFVDATTITECLHTFCKSCIVKYLQTSKHCPMCNIKIHETQ-PLLNLKLDRVMQEIVYKLVPGLQNDEERRIREFYQSRGLDR 132
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Sea Lamprey
Match: PCGF3 (polycomb group ring finger 3 [Source:HGNC Symbol;Acc:HGNC:10066])

HSP 1 Score: 95.5153 bits (236), Expect = 3.735e-25
Identity = 46/100 (46.00%), Postives = 64/100 (64.00%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELN 354
            K+KL  LNAH+ C LC GYLID T +T+CLHTFCKSC+ +YLE +  CP C+ +I ++   +  +  D  +Q  +YKLVP L ++EM+    FY    L 
Sbjct:    5 KLKLRELNAHITCPLCRGYLIDATTVTECLHTFCKSCLVRYLEDHNTCPTCKIVIHQSHPTQY-IGHDRTMQDIVYKLVPGLQEAEMKRQREFYWTRGLE 103
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Sea Lamprey
Match: pcgf6 (polycomb group ring finger 6 [Source:ZFIN;Acc:ZDB-GENE-060526-178])

HSP 1 Score: 85.1149 bits (209), Expect = 4.837e-20
Identity = 40/98 (40.82%), Postives = 64/98 (65.31%), Query Frame = 1 
Query:   58 VKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL 351
            V L  +N+ + C LC GYL+D T +T+CLHTFCKSCI K+ +++  CP C  ++ +T+    +++ D  +Q  +YKLVPNL ++E + +  FY +  L
Sbjct:    4 VSLVDVNSFITCYLCKGYLVDATTITECLHTFCKSCIVKHFDYSNRCPQCNVVVHQTQ-PLYNIRSDGTMQDIVYKLVPNLEENEKRRMRDFYLSRGL 100
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Sea Lamprey
Match: pcgf5b (polycomb group ring finger 5b [Source:NCBI gene;Acc:692252])

HSP 1 Score: 82.8037 bits (203), Expect = 4.686e-19
Identity = 42/110 (38.18%), Postives = 66/110 (60.00%), Query Frame = 1 
Query:   49 LSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFY---QNEELNENEFN 369
            + + +   LN  + C+LC GYLI PT +T+CLHTFCKSCI ++ E +  CP C   + ET   ++ L+ D  L++ I+KL+P L + E +    F+   +N+E   +E N
Sbjct:    4 VRRARARDLNPFVTCSLCRGYLIKPTAVTECLHTFCKSCIVQHFEESNECPKCGIQVHETNPLEM-LRQDKTLEEIIFKLIPGLRECEEKRERDFWNAQRNQEYRNDEEN 112
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Nematostella
Match: EDO43600 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY97])

HSP 1 Score: 85.1149 bits (209), Expect = 2.810e-21
Identity = 39/88 (44.32%), Postives = 58/88 (65.91%), Query Frame = 1 
Query:   49 LSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSE 312
            L  + L  LN H+IC LCGGYL+D T + +CLH+FC+ CI +YLE +  CP+C   I +TR   ++++ D +LQ  +YK+VP +   E
Sbjct:    2 LRTLSLKELNPHIICVLCGGYLVDATTIIECLHSFCRCCIVRYLETSYRCPVCDAEIHKTR-PLLNIRADNVLQDIVYKVVPGMYFGE 88
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Nematostella
Match: EDO43598 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY97])

HSP 1 Score: 85.1149 bits (209), Expect = 2.810e-21
Identity = 39/88 (44.32%), Postives = 58/88 (65.91%), Query Frame = 1 
Query:   49 LSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSE 312
            L  + L  LN H+IC LCGGYL+D T + +CLH+FC+ CI +YLE +  CP+C   I +TR   ++++ D +LQ  +YK+VP +   E
Sbjct:    2 LRTLSLKELNPHIICVLCGGYLVDATTIIECLHSFCRCCIVRYLETSYRCPVCDAEIHKTR-PLLNIRADNVLQDIVYKVVPGMYFGE 88
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Nematostella
Match: EDO43596 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY94])

HSP 1 Score: 84.3445 bits (207), Expect = 5.737e-21
Identity = 38/88 (43.18%), Postives = 58/88 (65.91%), Query Frame = 1 
Query:   49 LSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSE 312
            L  + L  LN H+IC LCGGYL+D T + +CLH+FC+ CI +YL+ +  CP+C   I +TR   ++++ D +LQ  +YK+VP +   E
Sbjct:    2 LRTLSLKELNPHIICVLCGGYLVDATTIIECLHSFCRGCIVRYLDTSYRCPVCDAEIHKTR-PLLNIRADNVLQDIVYKVVPGMYFGE 88
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Nematostella
Match: EDO37122 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGN9])

HSP 1 Score: 85.8853 bits (211), Expect = 1.055e-20
Identity = 45/102 (44.12%), Postives = 62/102 (60.78%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRY--CPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELN 354
            K++L  LN H+ C LC GYLI PT +T+CLHTFC+SCI    +      CP C  LI ET   ++ L+ D  L+  IYKLVP L + E++    FY++  L+
Sbjct:    3 KLQLRELNPHITCGLCRGYLIKPTTITECLHTFCRSCIILRFQDGEVNLCPTCNILIHETNPLEM-LRSDKTLEDIIYKLVPGLQEDEIRRTKEFYESYSLS 103
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Nematostella
Match: EDO42686 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0J2])

HSP 1 Score: 82.8037 bits (203), Expect = 2.561e-20
Identity = 40/99 (40.40%), Postives = 61/99 (61.62%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEEL 351
            +VK++ LN H IC LC GYLI+P  +T+C+HTFCKSC+ +++     CP+C  +I ET     +++ D  +Q  I K+ P L K E +    FY+ + L
Sbjct:    2 RVKVTDLNPHFICKLCNGYLINPVTITECIHTFCKSCLLRHISLVNRCPVCNEVIHET-TPIYNIRVDRTMQDIINKIFPKLEKEENRRERKFYRTKGL 99
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Medaka
Match: ENSORLT00000040811.1 (polycomb group ring finger 2 [Source:NCBI gene;Acc:101173438])

HSP 1 Score: 105.531 bits (262), Expect = 3.792e-26
Identity = 71/226 (31.42%), Postives = 111/226 (49.12%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFY-QNEELNENE----FNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENG-IFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFM 714
            +VK++ LN HL C LC GYLID T + +CLH+FCK+CI  +L+ N++CP C   +Q++   ++S++ D  LQ  +YKLVP L K EM+    FY +N  L   E    FN++  E + L     + N +   ++  T  +K+                             NG  FL C   + V  + K + +K  + P+ Y   + Y D+ L   YTL +I + 
Sbjct:    8 RVKITELNPHLTCPLCAGYLIDATTIVECLHSFCKTCIVTFLKTNKFCPRCDIQVQKS-CPQLSIRADKTLQDIVYKLVPGLFKDEMKRRRDFYAENRVLEPGEVVETFNIAEDEIISLSIQFYERNKNNERQRPETEGDKA-----------------------------NGKRFLQCPAAMSVMHLAKFLRSKMDI-PNNYRVEVLYGDEPLKDYYTLMDIAYF 202
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Medaka
Match: bmi1a (bmi1 polycomb ring finger oncogene 1a [Source:NCBI gene;Acc:321505])

HSP 1 Score: 105.145 bits (261), Expect = 4.466e-26
Identity = 45/106 (42.45%), Postives = 71/106 (66.98%), Query Frame = 1 
Query:   43 NNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNEN 360
            +  +++K++ LN HLIC LCGGY ID T + +CLH+FCK CI +YLE ++YCP+C   + +T+   ++++ D  LQ  +YKLVP L K+EM+    FY    ++ +
Sbjct:    2 HRTTRIKITELNPHLICVLCGGYFIDATTIIECLHSFCKMCIVRYLETSKYCPICDVQVHKTKP-LLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAEHPVDAS 106
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Medaka
Match: PCGF3 (polycomb group ring finger 3 [Source:NCBI gene;Acc:101171923])

HSP 1 Score: 94.3597 bits (233), Expect = 1.246e-22
Identity = 44/95 (46.32%), Postives = 63/95 (66.32%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQ 339
            K+ L  +NAH+ C LC GYLID T +T+CLHTFC+SC+ KYLE N  CP C+ +I ++   +  +  D  +Q  +YKLVP L ++E++    FYQ
Sbjct:   13 KINLCHINAHITCRLCEGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQY-IGHDRTMQDIVYKLVPGLQEAEIKKQREFYQ 106
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Medaka
Match: PCGF3 (polycomb group ring finger 3 [Source:NCBI gene;Acc:101171923])

HSP 1 Score: 94.3597 bits (233), Expect = 1.810e-22
Identity = 44/95 (46.32%), Postives = 63/95 (66.32%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQ 339
            K+ L  +NAH+ C LC GYLID T +T+CLHTFC+SC+ KYLE N  CP C+ +I ++   +  +  D  +Q  +YKLVP L ++E++    FYQ
Sbjct:   13 KINLCHINAHITCRLCEGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQY-IGHDRTMQDIVYKLVPGLQEAEIKKQREFYQ 106
[Close]
BLAST of Polycomb group ring finger 2 vs. Ensembl Medaka
Match: PCGF3 (polycomb group ring finger 3 [Source:NCBI gene;Acc:101171923])

HSP 1 Score: 94.3597 bits (233), Expect = 3.352e-22
Identity = 44/95 (46.32%), Postives = 63/95 (66.32%), Query Frame = 1 
Query:   55 KVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQ 339
            K+ L  +NAH+ C LC GYLID T +T+CLHTFC+SC+ KYLE N  CP C+ +I ++   +  +  D  +Q  +YKLVP L ++E++    FYQ
Sbjct:   13 KINLCHINAHITCRLCEGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQY-IGHDRTMQDIVYKLVPGLQEAEIKKQREFYQ 106
[Close]
BLAST of Polycomb group ring finger 2 vs. Planmine SMEST
Match: SMESG000066342.1 (SMESG000066342.1)

HSP 1 Score: 397.897 bits (1021), Expect = 1.602e-141
Identity = 244/245 (99.59%), Postives = 245/245 (100.00%), Query Frame = 1 
Query:   37 MNNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNENEFNVSSVEXXXXXXXXXXXXXXXTYKQKVTSENKXXXXXXXXXXXXXXXXXDILTNLIDKIVMENGIFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFMNKLEYPDGLNLLFDFTSSK 771
            MNNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNENEFNVSSVEKLCLL+NDDKLNLSLTYKQKVTSENKSSAPSTNSTSSPENESSDILTNLIDKIVMENGIFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFMNKLEYPDGLNLLFDFTSSK
Sbjct:    1 MNNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELNENEFNVSSVEKLCLLENDDKLNLSLTYKQKVTSENKSSAPSTNSTSSPENESSDILTNLIDKIVMENGIFLLCSTQIKVDQVKKLILNKYHLNPHEYVTSLWYNDDCLNSDYTLSEIMFMNKLEYPDGLNLLFDFTSSK 245
[Close]
BLAST of Polycomb group ring finger 2 vs. Planmine SMEST
Match: SMESG000076466.1 (SMESG000076466.1)

HSP 1 Score: 87.8113 bits (216), Expect = 1.644e-20
Identity = 44/103 (42.72%), Postives = 66/103 (64.08%), Query Frame = 1 
Query:   49 LSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGK-VSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQNEELN 354
            + K+K+S LN  + C +C GYLID   +T+CLHTFCKSCI KYLE N  CP C+ +I  +     +S+  D  +Q+ +YKLVPNL + E +    +Y+  +++
Sbjct:    1 MKKIKVSSLNKFITCFICKGYLIDAVSVTECLHTFCKSCIVKYLEDNNDCPQCKIVIHLSHPENCISI--DRTMQEIVYKLVPNLKECERKRREEYYRGIDVD 101
[Close]
BLAST of Polycomb group ring finger 2 vs. Planmine SMEST
Match: SMESG000072501.1 (SMESG000072501.1)

HSP 1 Score: 86.2705 bits (212), Expect = 1.378e-19
Identity = 40/94 (42.55%), Postives = 61/94 (64.89%), Query Frame = 1 
Query:   61 KLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFYQN 342
            K+  LN  + C LC GYLID T + +C+H+FCK+CI K+LE    CP C+C + ET+   + +K D +LQ  +Y+L P++ K EM++   F+ N
Sbjct:    8 KVKDLNDFVKCNLCYGYLIDATTVIECMHSFCKTCIMKHLEDFNTCPTCECRLHETK-PYLDVKTDKVLQSIVYQLFPSVFKDEMKSRREFHSN 100
[Close]
BLAST of Polycomb group ring finger 2 vs. Planmine SMEST
Match: SMESG000007981.1 (SMESG000007981.1)

HSP 1 Score: 46.2098 bits (108), Expect = 7.233e-6
Identity = 23/57 (40.35%), Postives = 34/57 (59.65%), Query Frame = 1 
Query:   70 VLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRY----CPLCQCLIQET 228
            ++  +L C +C  Y I P ++T C HTFC+SC+ ++    RY    CPLCQ  I+ T
Sbjct:  118 LIEDYLRCQICREYFIKP-VITNCGHTFCQSCLDQWALRTRYGGGNCPLCQHQIEYT 173
[Close]
BLAST of Polycomb group ring finger 2 vs. Planmine SMEST
Match: SMESG000007981.1 (SMESG000007981.1)

HSP 1 Score: 46.2098 bits (108), Expect = 8.759e-6
Identity = 23/57 (40.35%), Postives = 34/57 (59.65%), Query Frame = 1 
Query:   70 VLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEHNRY----CPLCQCLIQET 228
            ++  +L C +C  Y I P ++T C HTFC+SC+ ++    RY    CPLCQ  I+ T
Sbjct:  133 LIEDYLRCQICREYFIKP-VITNCGHTFCQSCLDQWALRTRYGGGNCPLCQHQIEYT 188
The following BLAST results are available for this feature:
BLAST of Polycomb group ring finger 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PCGF23.686e-3032.49polycomb group ring finger 2 [Source:HGNC Symbol;A... [more]
PCGF23.686e-3032.49polycomb group ring finger 2 [Source:HGNC Symbol;A... [more]
PCGF23.686e-3032.49polycomb group ring finger 2 [Source:HGNC Symbol;A... [more]
PCGF23.686e-3032.49polycomb group ring finger 2 [Source:HGNC Symbol;A... [more]
PCGF23.686e-3032.49polycomb group ring finger 2 [Source:HGNC Symbol;A... [more]
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BLAST of Polycomb group ring finger 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
mig-326.013e-1144.64pep chromosome:WBcel235:IV:12089247:12092213:-1 ge... [more]
mig-326.013e-1144.64pep chromosome:WBcel235:IV:12089286:12092213:-1 ge... [more]
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BLAST of Polycomb group ring finger 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
l(3)73Ah3.835e-2241.58gene:FBgn0002283 transcript:FBtr0307336[more]
l(3)73Ah3.835e-2241.58gene:FBgn0002283 transcript:FBtr0075311[more]
Psc2.631e-2142.11gene:FBgn0005624 transcript:FBtr0087798[more]
Psc2.631e-2142.11gene:FBgn0005624 transcript:FBtr0345196[more]
Psc2.631e-2142.11gene:FBgn0005624 transcript:FBtr0345375[more]
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BLAST of Polycomb group ring finger 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pcgf17.354e-2850.50polycomb group ring finger 1 [Source:NCBI gene;Acc... [more]
pcgf11.024e-2749.06polycomb group ring finger 1 [Source:NCBI gene;Acc... [more]
bmi1a5.386e-2628.51bmi1 polycomb ring finger oncogene 1a [Source:NCBI... [more]
bmi1a5.386e-2628.51bmi1 polycomb ring finger oncogene 1a [Source:NCBI... [more]
bmi1b7.723e-2642.11bmi1 polycomb ring finger oncogene 1b [Source:NCBI... [more]
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BLAST of Polycomb group ring finger 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
qprt2.047e-2728.96quinolinate phosphoribosyltransferase [Source:Xenb... [more]
vta16.363e-2729.44vesicle (multivesicular body) trafficking 1 [Sourc... [more]
qprt8.673e-2747.37quinolinate phosphoribosyltransferase [Source:Xenb... [more]
vta11.342e-2545.74vesicle (multivesicular body) trafficking 1 [Sourc... [more]
pcgf31.651e-2346.88polycomb group ring finger 3 [Source:NCBI gene;Acc... [more]
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BLAST of Polycomb group ring finger 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pcgf22.919e-3134.06polycomb group ring finger 2 [Source:MGI Symbol;Ac... [more]
Pcgf22.919e-3134.06polycomb group ring finger 2 [Source:MGI Symbol;Ac... [more]
Pcgf22.919e-3134.06polycomb group ring finger 2 [Source:MGI Symbol;Ac... [more]
Pcgf22.919e-3134.06polycomb group ring finger 2 [Source:MGI Symbol;Ac... [more]
Bmi12.247e-2847.37Bmi1 polycomb ring finger oncogene [Source:MGI Sym... [more]
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BLAST of Polycomb group ring finger 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P23798|PCGF2_MOUSE2.042e-3034.06Polycomb group RING finger protein 2 OS=Mus muscul... [more]
sp|P35227|PCGF2_HUMAN1.770e-2932.49Polycomb group RING finger protein 2 OS=Homo sapie... [more]
sp|Q4QR06|PCGF1_XENLA2.791e-2748.70Polycomb group RING finger protein 1 OS=Xenopus la... [more]
sp|Q28H21|PCGF1_XENTR4.285e-2748.70Polycomb group RING finger protein 1 OS=Xenopus tr... [more]
sp|Q7ZYZ7|PCGF1_DANRE4.761e-2749.06Polycomb group RING finger protein 1 OS=Danio reri... [more]
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BLAST of Polycomb group ring finger 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G7YJ332.485e-3755.46Polycomb group RING finger protein 2 (Fragment) OS... [more]
A0A183W0Y86.496e-3561.62RING-type domain-containing protein OS=Trichobilha... [more]
A0A075A7N07.937e-3552.85RING-type domain-containing protein (Fragment) OS=... [more]
A0A4S2M8E61.914e-3455.17RING-type domain-containing protein OS=Opisthorchi... [more]
A0A183K3Y24.366e-3360.61RING-type domain-containing protein OS=Schistosoma... [more]
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BLAST of Polycomb group ring finger 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pcgf14.708e-2849.06polycomb group ring finger 1 [Source:NCBI gene;Acc... [more]
pcgf17.143e-2850.50polycomb group ring finger 1 [Source:NCBI gene;Acc... [more]
bmi1a7.402e-2647.37BMI1 proto-oncogene, polycomb ring finger [Source:... [more]
bmi1b1.094e-2546.32polycomb complex protein BMI-1-B-like [Source:NCBI... [more]
PCGF32.331e-2347.37polycomb group ring finger 3 [Source:NCBI gene;Acc... [more]
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BLAST of Polycomb group ring finger 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bmi1b3.821e-2930.36bmi1 polycomb ring finger oncogene 1b [Source:NCBI... [more]
pcgf14.673e-2748.00polycomb group ring finger 1 [Source:NCBI gene;Acc... [more]
PCGF33.735e-2546.00polycomb group ring finger 3 [Source:HGNC Symbol;A... [more]
pcgf64.837e-2040.82polycomb group ring finger 6 [Source:ZFIN;Acc:ZDB-... [more]
pcgf5b4.686e-1938.18polycomb group ring finger 5b [Source:NCBI gene;Ac... [more]
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BLAST of Polycomb group ring finger 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Polycomb group ring finger 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO436002.810e-2144.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO435982.810e-2144.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO435965.737e-2143.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371221.055e-2044.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO426862.561e-2040.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Polycomb group ring finger 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000040811.13.792e-2631.42polycomb group ring finger 2 [Source:NCBI gene;Acc... [more]
bmi1a4.466e-2642.45bmi1 polycomb ring finger oncogene 1a [Source:NCBI... [more]
PCGF31.246e-2246.32polycomb group ring finger 3 [Source:NCBI gene;Acc... [more]
PCGF31.810e-2246.32polycomb group ring finger 3 [Source:NCBI gene;Acc... [more]
PCGF33.352e-2246.32polycomb group ring finger 3 [Source:NCBI gene;Acc... [more]
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BLAST of Polycomb group ring finger 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000066342.11.602e-14199.59SMESG000066342.1[more]
SMESG000076466.11.644e-2042.72SMESG000076466.1[more]
SMESG000072501.11.378e-1942.55SMESG000072501.1[more]
SMESG000007981.17.233e-640.35SMESG000007981.1[more]
SMESG000007981.18.759e-640.35SMESG000007981.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005538 ID=SMED30005538|Name=Polycomb group ring finger 2|organism=Schmidtea mediterranea sexual|type=transcript|length=824bp
GTTTAATTATCGTTAATTATTTTGTAACAATTTTAAATGAATAACAATTT
AAGTAAAGTTAAATTATCAGTTTTAAATGCTCATTTAATTTGTGCTCTCT
GTGGAGGATATTTAATTGATCCTACTATGCTTACTCAATGTTTGCATACA
TTTTGCAAAAGTTGCATTTTTAAGTATTTAGAACATAATCGATATTGTCC
TCTATGTCAATGTTTAATTCAAGAAACACGGATGGGAAAAGTCAGTTTAA
AGCCAGATCTCATATTACAAAAAGCTATTTATAAATTAGTTCCTAATCTT
TTGAAATCAGAAATGCAAAATATAAACTATTTTTATCAAAATGAAGAATT
AAATGAAAATGAATTTAATGTTTCATCCGTTGAAAAATTATGCCTTTTAA
AAAATGATGACAAACTAAATTTATCATTGACTTATAAGCAAAAAGTAACT
TCTGAAAACAAGTCTTCAGCTCCCTCTACAAATTCTACATCTTCGCCAGA
AAATGAATCAAGTGACATTCTTACTAATCTCATTGATAAAATTGTAATGG
AAAATGGAATATTTTTACTGTGCTCTACTCAAATAAAGGTTGATCAAGTT
AAAAAATTGATTTTAAATAAATATCATCTGAATCCTCATGAATATGTTAC
AAGCTTATGGTATAATGATGACTGTTTAAATTCCGATTACACTTTAAGTG
AAATTATGTTCATGAATAAATTGGAGTATCCAGATGGATTAAATTTATTA
TTTGATTTTACATCTAGTAAGTAGAACGTTAATTTGTTTCATAGTTCTTG
GCTTATGCTGTATCCTTCCTTGAC
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protein sequence of SMED30005538-orf-1

>SMED30005538-orf-1 ID=SMED30005538-orf-1|Name=SMED30005538-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=246bp
MNNNLSKVKLSVLNAHLICALCGGYLIDPTMLTQCLHTFCKSCIFKYLEH
NRYCPLCQCLIQETRMGKVSLKPDLILQKAIYKLVPNLLKSEMQNINYFY
QNEELNENEFNVSSVEKLCLLKNDDKLNLSLTYKQKVTSENKSSAPSTNS
TSSPENESSDILTNLIDKIVMENGIFLLCSTQIKVDQVKKLILNKYHLNP
HEYVTSLWYNDDCLNSDYTLSEIMFMNKLEYPDGLNLLFDFTSSK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0000122negative regulation of transcription from RNA polymerase II promoter
GO:0009952anterior/posterior pattern specification
GO:0016573histone acetylation
GO:0036353histone H2A-K119 monoubiquitination
GO:0048704embryonic skeletal system morphogenesis
GO:0048706embryonic skeletal system development
GO:0070301cellular response to hydrogen peroxide
GO:2001234negative regulation of apoptotic signaling pathway
Vocabulary: cellular component
TermDefinition
GO:0000790nuclear chromatin
GO:0001739sex chromatin
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0016604nuclear body
GO:0031519PcG protein complex
GO:0035102PRC1 complex
Vocabulary: molecular function
TermDefinition
GO:0003682chromatin binding
GO:0005515protein binding
GO:0008270zinc ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
Vocabulary: INTERPRO
TermDefinition
IPR001841Znf_RING
IPR013083Znf_RING/FYVE/PHD
IPR017907Znf_RING_CS
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001841Zinc finger, RING-typeSMARTSM00184ring_2coord: 19..57
e-value: 3.9E-5
score: 33.1
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 19..58
score: 11.825
NoneNo IPR availableGENE3DG3DSA:3.10.20.90coord: 117..245
e-value: 2.2E-10
score: 42.3
NoneNo IPR availablePFAMPF13923zf-C3HC4_2coord: 19..57
e-value: 5.4E-11
score: 42.2
NoneNo IPR availablePANTHERPTHR10825RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENTcoord: 6..228
NoneNo IPR availableCDDcd16525RING-HC_PCGFcoord: 17..57
e-value: 2.63602E-17
score: 71.122
NoneNo IPR availableCDDcd17082RAWUL_PCGF2_likecoord: 126..226
e-value: 1.34429E-5
score: 41.1683
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..20
score: 0.479
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 11..81
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 3..110
e-value: 3.4E-22
score: 80.3
IPR017907Zinc finger, RING-type, conserved sitePROSITEPS00518ZF_RING_1coord: 35..44