Receptor type tyrosine protein phosphatase

Overview
NameReceptor type tyrosine protein phosphatase
Smed IDSMED30005517
Length (bp)6411
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Receptor type tyrosine protein phosphatase (SMED30005517) t-SNE clustered cells

Violin plots show distribution of expression levels for Receptor type tyrosine protein phosphatase (SMED30005517) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Receptor type tyrosine protein phosphatase (SMED30005517) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Receptor type tyrosine protein phosphatase (SMED30005517) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30005517

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 16

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30005517h1SMcG0015883 SmedASXL_015370SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30005517h1SMcG0015883 Contig38468uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005517h1SMcG0015883 Contig38468newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005517h1SMcG0015883 Contig49491uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005517h1SMcG0015883 Contig49491newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30005517h1SMcG0015883 dd_Smed_v4_10176_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30005517h1SMcG0015883 dd_Smed_v4_10176_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30005517h1SMcG0015883 dd_Smed_v4_10176_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30005517h1SMcG0015883 dd_Smed_v4_10176_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30005517h1SMcG0015883 dd_Smed_v4_10176_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30005517h1SMcG0015883 dd_Smed_v4_10176_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30005517h1SMcG0015883 dd_Smed_v4_10176_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005517h1SMcG0015883 Contig51424newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30005517h1SMcG0015883 Contig51424uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30005517h1SMcG0015883 dd_Smed_v6_10176_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30005517h1SMcG0015883 OX_Smed_1.0.07565ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Human
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668])

HSP 1 Score: 865.144 bits (2234), Expect = 0.000e+0
Identity = 402/610 (65.90%), Postives = 478/610 (78.36%), Query Frame = 1
Query: 4393 DSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            DS    N  ++ +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQF Y  ALEYL SFD + +
Sbjct:  912 DSGYPGNLHSSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT 1505          

HSP 2 Score: 247.669 bits (631), Expect = 3.143e-65
Identity = 204/715 (28.53%), Postives = 320/715 (44.76%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSG------LSAPFIFDIVKTRPGNI 2340
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRS   G++  ++  + D G YEC A N  G+  S    L +R   + P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +               G+H      +E+ I I P  T YR+  L PN+LY+  LAAR+  G+G S T  +              V+ +  TS+ + W    +N  S   FKI     K +E VD                       + +I +L+  ++Y  VL + G+S       ++A    D+++T+P  I
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEELYKEIDGV-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYK-----DGEH-----GEEQRITIEPG-TSYRLQGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIP-ENYNSAMPFKILYDDGKMVEEVDGRAT-------------------QKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFI 694          

HSP 3 Score: 62.7734 bits (151), Expect = 1.049e-8
Identity = 65/269 (24.16%), Postives = 122/269 (45.35%), Query Frame = 1
Query: 2611 YEFSVAAMNTADIGLEVK-LNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK--NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNT--LDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRV 3399
            YEF V A+N    G   + +   T E AP S P  +    ++S ++ + W+ P  E  NG +  Y+V Y     +  N  ++     +    I  L     Y+ +V AFT +G GP SSD+   T   +P  P+N +A   +E  I ++W    ++ I    +++ Y      KD E      + + P T   L  ++ NS Y   + ++   +  GL    +TA+IS    ++ +   +   +  ++ S+ + W+ P+ +++   F++
Sbjct:  379 YEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI--ANYELVY------KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAAR---SPQGL--GASTAEISAR-TMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKI 631          

HSP 4 Score: 55.0694 bits (131), Expect = 1.958e-6
Identity = 137/562 (24.38%), Postives = 217/562 (38.61%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLY----------NGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA--------KGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSI----------DNTVLGLKQIPNIHPWPPDNKNITYNVTD--------LRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQ 1770
            RL V++E   PR G   I + PQ + V    TA   C   GNP   ++             NG  K +     G  L+I   + +D    + +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I          IT + + +P      PG  V    TA         GNP P   ++ Q H+P N     E +    D      Y     +     +  V V V  I + P +       P   Q S EQ P S  P +    M++  +I          +  + G +    + P    N  + +NV D        L P   YSVKV+AF+ ++GD   S  I + T+   P   P +  A  ++ TSI + W PP   +  I +Y + Y ++ +H   Q    E    + R+  L  N+ Y+ ++ A +  G G  +    I  R        NF    +  TS+ L W  P+
Sbjct:  112 RLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIG-ALQIEQSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDV-------RQSANYTCVAMSTLGVIEAIAQ--------ITVKALPKP------PGTPVVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKN----SEELYKEIDGVATTRYSVAGLSPYSDYEFRV-VAVNNIGRGPPS------EPVLTQTS-EQAP-SSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPP--RSDTIANYELVY-KDGEHGEEQRITIEPGTSY-RLQGLKPNSLYYFRLAARSPQGLGASTA--EISARTMQSMFAKNFHVKAVMKTSVLLSWEIPE 621          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Human
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668])

HSP 1 Score: 865.144 bits (2234), Expect = 0.000e+0
Identity = 402/610 (65.90%), Postives = 478/610 (78.36%), Query Frame = 1
Query: 4393 DSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            DS    N  ++ +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQF Y  ALEYL SFD + +
Sbjct:  912 DSGYPGNLHSSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT 1505          

HSP 2 Score: 247.669 bits (631), Expect = 2.812e-65
Identity = 204/715 (28.53%), Postives = 320/715 (44.76%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSG------LSAPFIFDIVKTRPGNI 2340
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRS   G++  ++  + D G YEC A N  G+  S    L +R   + P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +               G+H      +E+ I I P  T YR+  L PN+LY+  LAAR+  G+G S T  +              V+ +  TS+ + W    +N  S   FKI     K +E VD                       + +I +L+  ++Y  VL + G+S       ++A    D+++T+P  I
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSVSIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEELYKEIDGV-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYK-----DGEH-----GEEQRITIEPG-TSYRLQGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIP-ENYNSAMPFKILYDDGKMVEEVDGRAT-------------------QKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFI 694          

HSP 3 Score: 62.7734 bits (151), Expect = 1.049e-8
Identity = 65/269 (24.16%), Postives = 122/269 (45.35%), Query Frame = 1
Query: 2611 YEFSVAAMNTADIGLEVK-LNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK--NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNT--LDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRV 3399
            YEF V A+N    G   + +   T E AP S P  +    ++S ++ + W+ P  E  NG +  Y+V Y     +  N  ++     +    I  L     Y+ +V AFT +G GP SSD+   T   +P  P+N +A   +E  I ++W    ++ I    +++ Y      KD E      + + P T   L  ++ NS Y   + ++   +  GL    +TA+IS    ++ +   +   +  ++ S+ + W+ P+ +++   F++
Sbjct:  379 YEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI--ANYELVY------KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAAR---SPQGL--GASTAEISAR-TMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKI 631          

HSP 4 Score: 57.3806 bits (137), Expect = 3.822e-7
Identity = 137/562 (24.38%), Postives = 218/562 (38.79%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLY----------NGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA--------KGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSI----------DNTVLGLKQIPNIHPWPPDNKNITYNVTD--------LRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQ 1770
            RL V++E   PR G   I + PQ + V    TA   C   GNP   ++             NG  K +  +  G  L+I   + +D    + +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I          IT + + +P      PG  V    TA         GNP P   ++ Q H+P N     E +    D      Y     +     +  V V V  I + P +       P   Q S EQ P S  P +    M++  +I          +  + G +    + P    N  + +NV D        L P   YSVKV+AF+ ++GD   S  I + T+   P   P +  A  ++ TSI + W PP   +  I +Y + Y ++ +H   Q    E    + R+  L  N+ Y+ ++ A +  G G  +    I  R        NF    +  TS+ L W  P+
Sbjct:  112 RLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSVSIG-ALQIEQSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDV-------RQSANYTCVAMSTLGVIEAIAQ--------ITVKALPKP------PGTPVVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKN----SEELYKEIDGVATTRYSVAGLSPYSDYEFRV-VAVNNIGRGPPS------EPVLTQTS-EQAP-SSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPP--RSDTIANYELVY-KDGEHGEEQRITIEPGTSY-RLQGLKPNSLYYFRLAARSPQGLGASTA--EISARTMQSMFAKNFHVKAVMKTSVLLSWEIPE 621          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Human
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668])

HSP 1 Score: 865.144 bits (2234), Expect = 0.000e+0
Identity = 402/610 (65.90%), Postives = 478/610 (78.36%), Query Frame = 1
Query: 4393 DSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            DS    N  ++ +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQF Y  ALEYL SFD + +
Sbjct:  912 DSGYPGNLHSSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT 1505          

HSP 2 Score: 247.669 bits (631), Expect = 2.812e-65
Identity = 204/715 (28.53%), Postives = 320/715 (44.76%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSG------LSAPFIFDIVKTRPGNI 2340
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRS   G++  ++  + D G YEC A N  G+  S    L +R   + P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +               G+H      +E+ I I P  T YR+  L PN+LY+  LAAR+  G+G S T  +              V+ +  TS+ + W    +N  S   FKI     K +E VD                       + +I +L+  ++Y  VL + G+S       ++A    D+++T+P  I
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSVSIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEELYKEIDGV-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYK-----DGEH-----GEEQRITIEPG-TSYRLQGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIP-ENYNSAMPFKILYDDGKMVEEVDGRAT-------------------QKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFI 694          

HSP 3 Score: 62.7734 bits (151), Expect = 1.049e-8
Identity = 65/269 (24.16%), Postives = 122/269 (45.35%), Query Frame = 1
Query: 2611 YEFSVAAMNTADIGLEVK-LNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK--NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNT--LDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRV 3399
            YEF V A+N    G   + +   T E AP S P  +    ++S ++ + W+ P  E  NG +  Y+V Y     +  N  ++     +    I  L     Y+ +V AFT +G GP SSD+   T   +P  P+N +A   +E  I ++W    ++ I    +++ Y      KD E      + + P T   L  ++ NS Y   + ++   +  GL    +TA+IS    ++ +   +   +  ++ S+ + W+ P+ +++   F++
Sbjct:  379 YEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI--ANYELVY------KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAAR---SPQGL--GASTAEISAR-TMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKI 631          

HSP 4 Score: 57.3806 bits (137), Expect = 3.822e-7
Identity = 137/562 (24.38%), Postives = 218/562 (38.79%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLY----------NGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA--------KGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSI----------DNTVLGLKQIPNIHPWPPDNKNITYNVTD--------LRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQ 1770
            RL V++E   PR G   I + PQ + V    TA   C   GNP   ++             NG  K +  +  G  L+I   + +D    + +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I          IT + + +P      PG  V    TA         GNP P   ++ Q H+P N     E +    D      Y     +     +  V V V  I + P +       P   Q S EQ P S  P +    M++  +I          +  + G +    + P    N  + +NV D        L P   YSVKV+AF+ ++GD   S  I + T+   P   P +  A  ++ TSI + W PP   +  I +Y + Y ++ +H   Q    E    + R+  L  N+ Y+ ++ A +  G G  +    I  R        NF    +  TS+ L W  P+
Sbjct:  112 RLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSVSIG-ALQIEQSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDV-------RQSANYTCVAMSTLGVIEAIAQ--------ITVKALPKP------PGTPVVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKN----SEELYKEIDGVATTRYSVAGLSPYSDYEFRV-VAVNNIGRGPPS------EPVLTQTS-EQAP-SSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPP--RSDTIANYELVY-KDGEHGEEQRITIEPGTSY-RLQGLKPNSLYYFRLAARSPQGLGASTA--EISARTMQSMFAKNFHVKAVMKTSVLLSWEIPE 621          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Human
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668])

HSP 1 Score: 865.144 bits (2234), Expect = 0.000e+0
Identity = 402/610 (65.90%), Postives = 478/610 (78.36%), Query Frame = 1
Query: 4393 DSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            DS    N  ++ +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQF Y  ALEYL SFD + +
Sbjct:  912 DSGYPGNLHSSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT 1505          

HSP 2 Score: 247.669 bits (631), Expect = 3.143e-65
Identity = 204/715 (28.53%), Postives = 320/715 (44.76%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSG------LSAPFIFDIVKTRPGNI 2340
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRS   G++  ++  + D G YEC A N  G+  S    L +R   + P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +               G+H      +E+ I I P  T YR+  L PN+LY+  LAAR+  G+G S T  +              V+ +  TS+ + W    +N  S   FKI     K +E VD                       + +I +L+  ++Y  VL + G+S       ++A    D+++T+P  I
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEELYKEIDGV-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYK-----DGEH-----GEEQRITIEPG-TSYRLQGLKPNSLYYFRLAARSPQGLGAS-TAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIP-ENYNSAMPFKILYDDGKMVEEVDGRAT-------------------QKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFI 694          

HSP 3 Score: 62.7734 bits (151), Expect = 1.049e-8
Identity = 65/269 (24.16%), Postives = 122/269 (45.35%), Query Frame = 1
Query: 2611 YEFSVAAMNTADIGLEVK-LNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK--NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNT--LDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRV 3399
            YEF V A+N    G   + +   T E AP S P  +    ++S ++ + W+ P  E  NG +  Y+V Y     +  N  ++     +    I  L     Y+ +V AFT +G GP SSD+   T   +P  P+N +A   +E  I ++W    ++ I    +++ Y      KD E      + + P T   L  ++ NS Y   + ++   +  GL    +TA+IS    ++ +   +   +  ++ S+ + W+ P+ +++   F++
Sbjct:  379 YEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI--ANYELVY------KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAAR---SPQGL--GASTAEISAR-TMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKI 631          

HSP 4 Score: 55.0694 bits (131), Expect = 1.958e-6
Identity = 137/562 (24.38%), Postives = 217/562 (38.61%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLY----------NGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA--------KGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSI----------DNTVLGLKQIPNIHPWPPDNKNITYNVTD--------LRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQ 1770
            RL V++E   PR G   I + PQ + V    TA   C   GNP   ++             NG  K +     G  L+I   + +D    + +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I          IT + + +P      PG  V    TA         GNP P   ++ Q H+P N     E +    D      Y     +     +  V V V  I + P +       P   Q S EQ P S  P +    M++  +I          +  + G +    + P    N  + +NV D        L P   YSVKV+AF+ ++GD   S  I + T+   P   P +  A  ++ TSI + W PP   +  I +Y + Y ++ +H   Q    E    + R+  L  N+ Y+ ++ A +  G G  +    I  R        NF    +  TS+ L W  P+
Sbjct:  112 RLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIG-ALQIEQSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDV-------RQSANYTCVAMSTLGVIEAIAQ--------ITVKALPKP------PGTPVVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKN----SEELYKEIDGVATTRYSVAGLSPYSDYEFRV-VAVNNIGRGPPS------EPVLTQTS-EQAP-SSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPP--RSDTIANYELVY-KDGEHGEEQRITIEPGTSY-RLQGLKPNSLYYFRLAARSPQGLGASTA--EISARTMQSMFAKNFHVKAVMKTSVLLSWEIPE 621          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Human
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668])

HSP 1 Score: 864.759 bits (2233), Expect = 0.000e+0
Identity = 401/604 (66.39%), Postives = 476/604 (78.81%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQF Y  ALEYL SFD + +
Sbjct: 1325 NFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT 1912          

HSP 2 Score: 268.47 bits (685), Expect = 2.366e-71
Identity = 272/1034 (26.31%), Postives = 449/1034 (43.42%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---------GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKL------EIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSP--TSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRHNLV--GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDP-----PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKS 3222
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRS         G++  ++  + D G YEC A N  G+  S    L      E+R  P  P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +               G+H      +E+ I I P  T YR+  L PN+LY+  LAAR+  G+G S   ++ RT    P++P   D+   SP  TSI + W+     +++  I+ + IK         VD  ++   +I  +P      SD  +Y++  LE    Y+I + +    G     +  +++T     VPS PP  + +  +   +          ++W  P+    HG IR Y++ +  +  G       LK   L+   +E + T T +      L     Y  +V A  T   G   K   VST  + P    + I+ T +  ++  I W PP+  +  G L  Y++ +    ++  T    S    +     + +   Y F++ A  KVG G           + +P+      P N+ +       ++++W+   L+  N I +  + + Y    IP  +     L V   T +TL  ++ ++ Y V +++
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVP--PRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEELYKEIDGV-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYK-----DGEH-----GEEQRITIEPG-TSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQ-DISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT------AVDGEDDKPHEILGIP------SDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRT--NEDVPSGPPRKVEVEAVNSTS--------VKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDT-TEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQM--NTALIQWHPPV--DTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGE-----EMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGI-ITKYTLLYRDINIP--LLPMEQLIVPADTTMTLTGLKPDTTYDVKVRA 996          

HSP 3 Score: 163.31 bits (412), Expect = 3.118e-39
Identity = 250/1085 (23.04%), Postives = 442/1085 (40.74%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLY----------NGMKKYV-------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNV-TDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA--------KGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAV--QVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTD--------LRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILP-DRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTP-NLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            RL V++E   PR G   I + PQ + V    TA   C   GNP   ++             NG  K +        PI   L +     +  +    + +C+  N SA  + +A  N+     +++    PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I          IT + + +P      PG  V    TA         GNP P   ++ Q H+P N            T + S+  L+  ++    +   NN   G     V  Q   +     P ++    +  T   + W++  E                 +  + G +    + P    N  + +NV D        L P   YSVKV+AF+ ++GD   S  I + T+   P   P +  A  ++ TSI + W PP   +  I +Y + Y ++ +H   Q    E    + R+  L  N+ Y+ ++ A +  G G  +       +  +P  PPQ  +      +STSI + W PP +       + ++    I    +    +K  EI  +P D T Y + +L   T Y I++ A T+ G G  S ++ +RT   VP+  P  ++V  ++ TS+ + WR  + N++   I  +++  +++++ E         V +     +  + ++ ++ II+ L+   +Y + + +  + G  A     +V T  G +   P L I   Q+            A I W PP+++ G ++ YR++      +  +E L     S K  E + T T+       +  G  Y F ++A N    G E+   +S  E  P  +P ++   G TS SV +SWQPP++   NGI+  Y + Y    +    +     P +    + GL+ +  Y  +VRA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y    + ++++       G  T   + N++    Y   + ++G  N  G + +  TAK +
Sbjct:  112 RLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIE----QSEESDQGKYECVATN-SAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDV-------RQSANYTCVAMSTLGVIEAIAQ--------ITVKALPKP------PGTPVVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP----------------NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPP--RSDTIANYELVY-KDGEHGEEQRITIEPGTSY-RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQ--DISCTSPSSTSILVSWQPPPV----EKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTE-HDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTT-GAVPGKPRLVINHTQMN----------TALIQWHPPVDTFGPLQGYRLKFG----RKDMEPLTTLEFSEK--EDHFTATD-------IHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SAMPFKILYDDGKMVEEVD-------GRATQKLIVNLKPEKSYSFVLTNRG--NSAGGLQHRVTAKTA 1104          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8])

HSP 1 Score: 687.182 bits (1772), Expect = 0.000e+0
Identity = 327/626 (52.24%), Postives = 430/626 (68.69%), Query Frame = 1
Query: 4354 VPLSHS--NGI--VTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHN-RTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +P SHS  NG   V     S+ +N  N     HP +P   LA++I  L+ N+NA F  E+ESI+ G HFTW  S+ ++NK KNRYANV AYDHSRVVLS +   PG DYINANY DGY K  +YIATQGPLPETF  FWRMVWE +   IVM+T LEER RVKCDQYWP+RG+  Y +  + +  LE+V LA+YTMR   L  K+  +P    E R++ H Q+T WPDHGVPD   P L+F+KRV++  P+D+GPI+ HCSAG+GRTGA+IV+D  L +++++  VD+YG V+ LRAQR+YMVQTEEQY+FI+DA+L+A   G+TEV    LH H+  L Q        PS    +G+++EF+HL+ L     +   ANLP NR KNR+++ +PY++ RV ++ +   DGSDYINAS+IDGY+ + AYIATQ P   T  DFWR +W+HNS I+ ML +  E G+E+CS YWP E     G ++VEPM EY+M  + LREFR+  SD  T   RT+RQF F++W + G P + +  +DF+ QVH T  QFG  GPITVHC +G GRT VF+ALSI+LDRMR+E  VD+F TV+LLR +R  M+Q  +QY F YL A EYL+++D F
Sbjct: 1377 LPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGD--IEVTLLESVHLAHYTMRTMRL--KMVGEP----EVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ--------PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRI--SDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYDNF 1984          

HSP 2 Score: 122.865 bits (307), Expect = 1.952e-27
Identity = 175/759 (23.06%), Postives = 317/759 (41.77%), Query Frame = 1
Query:  868 GHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDK---ESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNL-QHPINQWQKSETTRQH--VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVP-NSPIGIDVRTLSPTSIAIRWR-------KGMDNEESISSFKIKVIKLKSIETV-------DNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHN-LVGPQNLIE-SLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMN-TADIGLEVKLNVSTR---ESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTI--RTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPD-PPINIEASRINENQIKVTW 3051
            G  +NLTC A G P P++ W       ++D +     +++L LT +    ++ C A +++G I+    V  K++P  PVNI   ++      I+W+  P+ +     + +        N  L   +  +      +    +  +  L  +  Y   V + +  +G    S  +  +TK   P++ P S  A +    SI VKW P  + NG IT Y VYY+ +L   PI +W++ +         I  L  ++ Y ++V A NS G  P+S    +  R G+P QP       + S  + L W  P   S +V                   ++ E+E+ +      + +T L P+  Y+  +AA ++ G G  +  M  +T   +P +SP  +     S  S+ IRW+        G+     I+ F+++  K  ++E+V       D+S+ +      VP      SD   Y+++DL    +Y+I + +    G        +VKT     VPS P N    +L   T   LT       WD P  ++G +  Y +  + +V  + ++E   K+R + ++   K         E   L     Y F + A N   D     + ++ T+     AP+   VS+D          I W+ P ++ +   +  Y +     G  ++ +  +T    +L   I GL   ++Y   + A  + G+   +++    T V  PD  PI+++   + + +I V+W
Sbjct:   70 GGNINLTCVAVGYPMPRVFWKKTDLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWKP-PKYNEAINKYVV--------NYRLKYSEGRSSRGKTMETLENSLVIDGLVAFQTYEFTVRS-AGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGYTVRY-----------NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVP------SDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLED--VPSAPRNFNA-ELTSATSVKLT-------WDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRY------FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLD-RDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATET-IATPVGSPDGEPIDVQY-EVMKGKIVVSW 782          

HSP 3 Score: 88.5817 bits (218), Expect = 5.862e-17
Identity = 188/904 (20.80%), Postives = 342/904 (37.83%), Query Frame = 1
Query: 1288 VTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVP-PQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEE--------------IKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNV-RTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKL------------KSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIIN-DLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIR---TTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFR-TVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPK-DIESCNTLDV------GPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKV-RSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYL-RILRVTEHLGIIRTYYLII-------EESIHTQKTNFSKYSFESLQSASKPISYSP 3849
            +  L P +RY V+VIA   + GDS  S  + + T++  P  PP       D+   + + W  P+ ++  +  Y V Y  N      +   +    +HV +T L  +  Y+ +V A +  G G  +EP        +P   P     A  +S S+ + W  P Q     VL  Y + Y  +       L + E +              + +  D T Y +++L P + Y I++AA T  G G  +++ V +T   VP++P   +    S TS+ + W        ++  + + + ++            K I  + +S++ + ++ S+   T+    +  +  N D E  +   I+   +      AP I  +   R       PP+  R+     K +   T +     W   + + G   +Y                        V  K V GT+  T    L  G VY+  +AA N           ++T   +PD  P+ +    +    + +SW+PP  E  NG + +Y+       +  T  R       P+  +  E +     Y F+V A T  G GP+S  +        L  PP N+     + +   V W+       K   F + Y  +   + D E    L V       P     + ++  +  Y   + +   +NR G  S+  T   S  P      V +L+   K   S+++ W+     +    F V   G   Y     + +   +    ++VD  +K+ +++    ++ P+M+Y I V       G   ++   Q     T    P FV  P+++  + T     + R+   TE  G I  Y++I+       E+ ++       K + E     ++ +S SP
Sbjct:  305 INGLEPDSRYFVRVIA-QNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDS-RRMQLTWDKPLYSS-PVVGYTVRY--NTSDGEKELTLTSPHEKHV-VTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPE---APEIVSVSLDRD-----EPPVVARIEWKMPKMKPNETPIEKYNLW---LRAQGYPDSY------------------------VKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYE-VMKGKIVVSWRPPSEEKRNGNITSYKA--ILSAMDATADRYEQPVPAPSTSSTFE-VNVRRAYLFKVAAATMKGIGPYSPVLTINPDPAALVGPPTNVRVEATSNSTAVVQWDFESQ---KADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLAVK-NNRQGPCSDPPTVLESVTPT---YMVQNLRVLWKTSNSVQLTWEYNGPRN--VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD--EKHREYL--WTNLRPHMMYTIHVGVRTLPPGARKYWP--QEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSP 1148          

HSP 4 Score: 65.0846 bits (157), Expect = 6.929e-10
Identity = 133/580 (22.93%), Postives = 237/580 (40.86%), Query Frame = 1
Query: 1279 TYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTI-VIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSR--NLQHPINQWQKS------ETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSIN---------LIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMT--ELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPV-SIDITGITSHSVNISWQPPLVENHNGILVNY--QVAYFTYGLKNTTIRTTSTPNLYALIE---------GLQENMLYTFQV 2919
            +Y ++DL PY+ Y + V A   T+    P  +I V++T E  PS+P ++  A   + TS+ + W  P  ANG +  Y VY  R  N +  + +  K       ++++++  +  L  N  Y  ++NA N  G G  SE   II + G+PP+        I S S++         + W  P++      ++    +    G   P    K + +    D TD   T   LW   +Y + LAA    G   + T  + T    P+  PI +    +    I + WR   + + + +    K I L +++   +  E     Q VPA +   S  +E    ++     +K+   ++   G  +P +   +   P  +V  PP N+R+      T        A + WD          ++ +++ +  P N +++ K + L V   +K            +L   K Y F V A+     G       +  ES   +Y V ++ +   TS+SV ++W+     N  G  VN+  +  Y  + L+    +T STP     ++          L+ +M+YT  V
Sbjct:  515 SYVLSDLLPYSSYEITVAA--STMDGYGPESSIRVVKTLEDVPSAP-RNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQ-GIPPE-----APEIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQG--YPDSYVKAKTV----DGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYEVMK-GKIVVSWRPPSEEKRNGNITSYKAI-LSAMDATADRYE-----QPVPAPST--SSTFEV---NVRRAYLFKVAAATMKGIGPYSPVL--TINPDPAALV-GPPTNVRVEATSNST--------AVVQWD---FESQKADSFVVKY-MHEPGNRMDTEKWKQLPVVSIDKE--NPKRFAVVSDLNAHKPYAFCVLAVKNNRQG-PCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRN-VGFYVNHTGRKDYVNHELQE---KTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHV 1045          

HSP 5 Score: 64.6994 bits (156), Expect = 9.145e-10
Identity = 95/417 (22.78%), Postives = 160/417 (38.37%), Query Frame = 1
Query: 1924 YHISLAARTEHGVGVSNT-MNVRTENRVP-NSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVS-TRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYF----------------------TYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIY 3099
            Y  ++ +    GVG+ +  +  +T+   P  +P+    R+L+  SI ++W         I+ +K+             +N++         +   +SD +   IN LE    Y + + +  S G S       V TR G  +P  P  + +  L  +           + WD P+ S   +  Y +R+N        +  K  +L+    +  VTG         L   K Y F VAA +    G   +  +S T  S P S P  +     +S SV I W+ P  +  NG+L  Y++ YF                      +  L   ++   S    Y L + L  +  Y   V A T  G GP SS    +T+  +P  P N  A   +   +K+TW+     N  ++G+ +Y
Sbjct:  213 YEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYY-----------TNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQG--IPGQPPMLTVKALDSRR--------MQLTWDKPLYSSPVV-GYTVRYNTS------DGEKELTLTSPHEKHVVTG---------LHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSS-YEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVY 591          

HSP 6 Score: 55.4546 bits (132), Expect = 5.499e-7
Identity = 79/294 (26.87%), Postives = 127/294 (43.20%), Query Frame = 1
Query: 2653 LEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLV-ENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLP-DPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDV-GPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRD-LSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFV-----DKYIKF 3507
            +E    V  +E  P   PV+I ++ +TS SV I+W+PP   E  N  +VNY++ Y + G +++  +T  T     +I+GL     Y F VR+   VG G  S  V  +T    P   P++ +A  +N + I V W      N  + G+K+YY    +   I      D      M T+  ++ +S Y V + ++  +    L + +  A    +P     L+V +L      R M++ W KP     +  + V  N        T + EK  +   P E   V     DKY  F
Sbjct:  132 IEATTTVIAKELPPP--PVNIVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKY-SEG-RSSRGKTMETLENSLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDS----RRMQLTWDKPLYSSPVVGYTVRYN--------TSDGEKELTLTSPHEKHVVTGLHPDKYYYF 409          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8])

HSP 1 Score: 686.797 bits (1771), Expect = 0.000e+0
Identity = 327/626 (52.24%), Postives = 430/626 (68.69%), Query Frame = 1
Query: 4354 VPLSHS--NGI--VTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHN-RTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +P SHS  NG   V     S+ +N  N     HP +P   LA++I  L+ N+NA F  E+ESI+ G HFTW  S+ ++NK KNRYANV AYDHSRVVLS +   PG DYINANY DGY K  +YIATQGPLPETF  FWRMVWE +   IVM+T LEER RVKCDQYWP+RG+  Y +  + +  LE+V LA+YTMR   L  K+  +P    E R++ H Q+T WPDHGVPD   P L+F+KRV++  P+D+GPI+ HCSAG+GRTGA+IV+D  L +++++  VD+YG V+ LRAQR+YMVQTEEQY+FI+DA+L+A   G+TEV    LH H+  L Q        PS    +G+++EF+HL+ L     +   ANLP NR KNR+++ +PY++ RV ++ +   DGSDYINAS+IDGY+ + AYIATQ P   T  DFWR +W+HNS I+ ML +  E G+E+CS YWP E     G ++VEPM EY+M  + LREFR+  SD  T   RT+RQF F++W + G P + +  +DF+ QVH T  QFG  GPITVHC +G GRT VF+ALSI+LDRMR+E  VD+F TV+LLR +R  M+Q  +QY F YL A EYL+++D F
Sbjct: 1596 LPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGD--IEVTLLESVHLAHYTMRTMRL--KMVGEP----EVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ--------PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRI--SDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYDNF 2203          

HSP 2 Score: 107.842 bits (268), Expect = 7.883e-23
Identity = 90/317 (28.39%), Postives = 143/317 (45.11%), Query Frame = 1
Query:  250 AKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM------KKYVIPIPSGL-MLRIPDVKLTDGKPV---RIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRR----TMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHR-PQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDK---ESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWE 1146
            A+++V P S TV+      FFC+ DGNP   +    NG       +  +  + +GL  LR   V L D   V     D  V NP   E   A L V  P   +P GFP+ +L       + G+   ++C V G    K  W +D  PLD+    R    T+   G++      +ED G YEC A N +G   S    L ++   + P + ++  +   V  G  +NLTC A G P P++ W       ++D +     +++L LT +    ++ C A +++G I+    V  K++P  PVNI   ++      I+W+
Sbjct:   48 ARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFERVSLDDNATVVSCSADNGVANPVVAE---ASLTVV-PRDKVPIGFPQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWKKTDLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWK 360          

HSP 3 Score: 103.605 bits (257), Expect = 1.629e-21
Identity = 140/584 (23.97%), Postives = 245/584 (41.95%), Query Frame = 1
Query: 1384 ETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNL-QHPINQWQKSETTRQH--VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVP-NSPIGIDVRTLSPTSIAIRWR-------KGMDNEESISSFKIKVIKLKSIETV-------DNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIR-HNLVGPQNLIE-SLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMN-TADIGLEVKLNVSTR---ESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTI--RTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPD-PPINIEASRINENQIKVTW 3051
            +TK   P++ P S  A +    SI VKW P  + NG IT Y VYY+ +L   PI +W++ +         I  L  ++ Y ++V A NS G  P+S    +  R G+P QP       + S  + L W  P   S +V                   ++ E+E+ +      + +T L P+  Y+  +AA ++ G G  +  M  +T   +P +SP  +     S  S+ IRW+        G+     I+ F+++  K  ++E+V       D+S+ +      VP      SD   Y+++DL    +Y+I + +    G        +VKT     VPS P N    +L   T   LT       WD P  ++G +  Y +    +V  + ++E   K+R + ++   K         E   L     Y F + A N   D     + ++ T+     AP+   VS+D          I W+ P ++ +   +  Y +     G  ++ +  +T    +L   I GL   ++Y   + A  + G+   +++    T V  PD  PI+++   + + +I V+W
Sbjct:  454 QTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGYTVRY-----------NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVP------SDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLED--VPSAPRNFNA-ELTSATSVKLT-------WDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRY------FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLD-RDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATET-IATPVGSPDGEPIDVQY-EVMKGKIVVSW 1001          

HSP 4 Score: 89.3521 bits (220), Expect = 3.303e-17
Identity = 195/934 (20.88%), Postives = 352/934 (37.69%), Query Frame = 1
Query: 1288 VTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVP-PQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEE--------------IKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNV-RTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKL------------KSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIIN-DLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIR---TTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFR-TVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPK-DIESCNTLDV------GPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKV-RSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYL-RILRVTEHLGIIRTYYLII-------EESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNISFWVGQDIWRSQY 3939
            +  L P +RY V+VIA   + GDS  S  + + T++  P  PP       D+   + + W  P+ ++  +  Y V Y  N      +   +    +HV +T L  +  Y+ +V A +  G G  +EP        +P   P     A  +S S+ + W  P Q     VL  Y + Y  +       L + E +              + +  D T Y +++L P + Y I++AA T  G G  +++ V +T   VP++P   +    S TS+ + W        ++  + + + ++            K I  + +S++ + ++ S+   T+    +  +  N D E  +   I+   +      AP I  +   R       PP+  R+     K +   T +     W   + + G   +Y                        V  K V GT+  T    L  G VY+  +AA N           ++T   +PD  P+ +    +    + +SW+PP  E  NG + +Y+       +  T  R       P+  +  E +     Y F+V A T  G GP+S  +        L  PP N+     + +   V W+       K   F + Y  +   + D E    L V       P     + ++  +  Y   + +   +NR G  S+  T   S  P      V +L+   K   S+++ W+     +    F V   G   Y     + +   +    ++VD  +K+ +++    ++ P+M+Y I V       G   ++   Q     T    P FV  P+++  + T     + R+   TE  G I  Y++I+       E+ ++       K + E     ++ +S SP      S  + +K S     VG D   + Y
Sbjct:  524 INGLEPDSRYFVRVIA-QNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDS-RRMQLTWDKPLYSS-PVVGYTVRY--NTSDGEKELTLTSPHEKHV-VTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPE---APEIVSVSLDRD-----EPPVVARIEWKMPKMKPNETPIEKYNLW---LRAQGYPDSY------------------------VKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYE-VMKGKIVVSWRPPSEEKRNGNITSYKA--ILSAMDATADRYEQPVPAPSTSSTFE-VNVRRAYLFKVAAATMKGIGPYSPVLTINPDPAALVGPPTNVRVEATSNSTAVVQWDFESQ---KADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLAVK-NNRQGPCSDPPTVLESVTPT---YMVQNLRVLWKTSNSVQLTWEYNGPRN--VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD--EKHREYL--WTNLRPHMMYTIHVGVRTLPPGARKYWP--QEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSP------SKKLKRKASE----VGDDSQSASY 1387          

HSP 5 Score: 65.0846 bits (157), Expect = 6.804e-10
Identity = 133/580 (22.93%), Postives = 237/580 (40.86%), Query Frame = 1
Query: 1279 TYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTI-VIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSR--NLQHPINQWQKS------ETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSIN---------LIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMT--ELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPV-SIDITGITSHSVNISWQPPLVENHNGILVNY--QVAYFTYGLKNTTIRTTSTPNLYALIE---------GLQENMLYTFQV 2919
            +Y ++DL PY+ Y + V A   T+    P  +I V++T E  PS+P ++  A   + TS+ + W  P  ANG +  Y VY  R  N +  + +  K       ++++++  +  L  N  Y  ++NA N  G G  SE   II + G+PP+        I S S++         + W  P++      ++    +    G   P    K + +    D TD   T   LW   +Y + LAA    G   + T  + T    P+  PI +    +    I + WR   + + + +    K I L +++   +  E     Q VPA +   S  +E    ++     +K+   ++   G  +P +   +   P  +V  PP N+R+      T        A + WD          ++ +++ +  P N +++ K + L V   +K            +L   K Y F V A+     G       +  ES   +Y V ++ +   TS+SV ++W+     N  G  VN+  +  Y  + L+    +T STP     ++          L+ +M+YT  V
Sbjct:  734 SYVLSDLLPYSSYEITVAA--STMDGYGPESSIRVVKTLEDVPSAP-RNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQ-GIPPE-----APEIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQG--YPDSYVKAKTV----DGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYEVMK-GKIVVSWRPPSEEKRNGNITSYKAI-LSAMDATADRYE-----QPVPAPST--SSTFEV---NVRRAYLFKVAAATMKGIGPYSPVL--TINPDPAALV-GPPTNVRVEATSNST--------AVVQWD---FESQKADSFVVKY-MHEPGNRMDTEKWKQLPVVSIDKE--NPKRFAVVSDLNAHKPYAFCVLAVKNNRQG-PCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRN-VGFYVNHTGRKDYVNHELQE---KTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHV 1264          

HSP 6 Score: 64.3142 bits (155), Expect = 1.117e-9
Identity = 95/417 (22.78%), Postives = 160/417 (38.37%), Query Frame = 1
Query: 1924 YHISLAARTEHGVGVSNT-MNVRTENRVP-NSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVS-TRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYF----------------------TYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIY 3099
            Y  ++ +    GVG+ +  +  +T+   P  +P+    R+L+  SI ++W         I+ +K+             +N++         +   +SD +   IN LE    Y + + +  S G S       V TR G  +P  P  + +  L  +           + WD P+ S   +  Y +R+N        +  K  +L+    +  VTG         L   K Y F VAA +    G   +  +S T  S P S P  +     +S SV I W+ P  +  NG+L  Y++ YF                      +  L   ++   S    Y L + L  +  Y   V A T  G GP SS    +T+  +P  P N  A   +   +K+TW+     N  ++G+ +Y
Sbjct:  432 YEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYY-----------TNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQG--IPGQPPMLTVKALDSRR--------MQLTWDKPLYSSPVV-GYTVRYNTS------DGEKELTLTSPHEKHVVTG---------LHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSS-YEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVY 810          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8])

HSP 1 Score: 686.411 bits (1770), Expect = 0.000e+0
Identity = 327/626 (52.24%), Postives = 430/626 (68.69%), Query Frame = 1
Query: 4354 VPLSHS--NGI--VTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHN-RTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +P SHS  NG   V     S+ +N  N     HP +P   LA++I  L+ N+NA F  E+ESI+ G HFTW  S+ ++NK KNRYANV AYDHSRVVLS +   PG DYINANY DGY K  +YIATQGPLPETF  FWRMVWE +   IVM+T LEER RVKCDQYWP+RG+  Y +  + +  LE+V LA+YTMR   L  K+  +P    E R++ H Q+T WPDHGVPD   P L+F+KRV++  P+D+GPI+ HCSAG+GRTGA+IV+D  L +++++  VD+YG V+ LRAQR+YMVQTEEQY+FI+DA+L+A   G+TEV    LH H+  L Q        PS    +G+++EF+HL+ L     +   ANLP NR KNR+++ +PY++ RV ++ +   DGSDYINAS+IDGY+ + AYIATQ P   T  DFWR +W+HNS I+ ML +  E G+E+CS YWP E     G ++VEPM EY+M  + LREFR+  SD  T   RT+RQF F++W + G P + +  +DF+ QVH T  QFG  GPITVHC +G GRT VF+ALSI+LDRMR+E  VD+F TV+LLR +R  M+Q  +QY F YL A EYL+++D F
Sbjct: 1592 LPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGD--IEVTLLESVHLAHYTMRTMRL--KMVGEP----EVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ--------PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRI--SDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYDNF 2199          

HSP 2 Score: 184.496 bits (467), Expect = 3.598e-46
Identity = 238/980 (24.29%), Postives = 411/980 (41.94%), Query Frame = 1
Query:  250 AKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM------KKYVIPIPSGL-MLRIPDVKLTDGKPV---RIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRR----TMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHR-PQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDK---ESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNL-QHPINQWQKSETTRQH--VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVP-NSPIGIDVRTLSPTSIAIRWR-------KGMDNEESISSFKIKVIKLKSIETV-------DNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHN-LVGPQNLIE-SLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMN-TADIGLEVKLNVSTR---ESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTI--RTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPD-PPINIEASRINENQIKVTW 3051
            A+++V P S TV+      FFC+ DGNP   +    NG       +  +  + +GL  LR   V L D   V     D  V NP   E   A L V  P   +P GFP+ +L       + G+   ++C V G    K  W +D  PLD+    R    T+   G++      +ED G YEC A N +G   S    L ++   + P + ++  +   V  G  +NLTC A G P P++ W       ++D +     +++L LT +    ++ C A +++G I+    V  K++P  PVNI   ++      I+W+  P+ +     + +        N  L   +  +      +    +  +  L  +  Y   V + +  +G    S  +  +TK   P++ P S  A +    SI VKW P  + NG IT Y VYY+ +L   PI +W++ +         I  L  ++ Y ++V A NS G  P+S    +  R G+P QP       + S  + L W  P   S +V                   ++ E+E+ +      + +T L P+  Y+  +AA ++ G G  +  M  +T   +P +SP  +     S  S+ IRW+        G+     I+ F+++  K  ++E+V       D+S+ +      VP      SD   Y+++DL    +Y+I + +    G        +VKT     VPS P N    +L   T   LT       WD P  ++G +  Y +  + +V  + ++E   K+R + ++   K         E   L     Y F + A N   D     + ++ T+     AP+   VS+D          I W+ P ++ +   +  Y +     G  ++ +  +T    +L   I GL   ++Y   + A  + G+   +++    T V  PD  PI+++   + + +I V+W
Sbjct:   48 ARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFERVSLDDNATVVSCSADNGVANPVVAE---ASLTVV-PRDKVPIGFPQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWKKTDLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWKP-PKYNEAINKYVV--------NYRLKYSEGRSSRGKTMETLENSLVIDGLVAFQTYEFTVRS-AGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGYTVRY-----------NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVP------SDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLED--VPSAPRNFNA-ELTSATSVKLT-------WDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRY------FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLD-RDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATET-IATPVGSPDGEPIDVQY-EVMKGKIVVSW 977          

HSP 3 Score: 83.1889 bits (204), Expect = 2.139e-15
Identity = 134/624 (21.47%), Postives = 238/624 (38.14%), Query Frame = 1
Query: 1288 VTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVP-PQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEE--------------IKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNV-RTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKL------------KSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIIN-DLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIR---TTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFR-TVVLLPDPPINIEASRINENQIKVTWEL 3057
            +  L P +RY V+VIA   + GDS  S  + + T++  P  PP       D+   + + W  P+ ++  +  Y V Y  N      +   +    +HV +T L  +  Y+ +V A +  G G  +EP        +P   P     A  +S S+ + W  P Q     VL  Y + Y  +       L + E +              + +  D T Y +++L P + Y I++AA T  G G  +++ V +T   VP++P   +    S TS+ + W        ++  + + + ++            K I  + +S++ + ++ S+   T+    +  +  N D E  +   I+   +      AP I  +   R       PP+  R+     K +   T +     W   + + G   +Y                        V  K V GT+  T    L  G VY+  +AA N           ++T   +PD  P+ +    +    + +SW+PP  E  NG + +Y+       +  T  R       P+  +  E +     Y F+V A T  G GP+S  +        L  PP N+     + +   V W+ 
Sbjct:  500 INGLEPDSRYFVRVIA-QNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDS-RRMQLTWDKPLYSS-PVVGYTVRY--NTSDGEKELTLTSPHEKHV-VTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPE---APEIVSVSLDRD-----EPPVVARIEWKMPKMKPNETPIEKYNLW---LRAQGYPDSY------------------------VKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYE-VMKGKIVVSWRPPSEEKRNGNITSYKA--ILSAMDATADRYEQPVPAPSTSSTFE-VNVRRAYLFKVAAATMKGIGPYSPVLTINPDPAALVGPPTNVRVEATSNSTAVVQWDF 1078          

HSP 4 Score: 64.6994 bits (156), Expect = 9.521e-10
Identity = 95/417 (22.78%), Postives = 160/417 (38.37%), Query Frame = 1
Query: 1924 YHISLAARTEHGVGVSNT-MNVRTENRVP-NSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVS-TRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYF----------------------TYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIY 3099
            Y  ++ +    GVG+ +  +  +T+   P  +P+    R+L+  SI ++W         I+ +K+             +N++         +   +SD +   IN LE    Y + + +  S G S       V TR G  +P  P  + +  L  +           + WD P+ S   +  Y +R+N        +  K  +L+    +  VTG         L   K Y F VAA +    G   +  +S T  S P S P  +     +S SV I W+ P  +  NG+L  Y++ YF                      +  L   ++   S    Y L + L  +  Y   V A T  G GP SS    +T+  +P  P N  A   +   +K+TW+     N  ++G+ +Y
Sbjct:  408 YEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYY-----------TNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQG--IPGQPPMLTVKALDSRR--------MQLTWDKPLYSSPVV-GYTVRYNTS------DGEKELTLTSPHEKHVVTG---------LHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSS-YEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVY 786          

HSP 5 Score: 64.6994 bits (156), Expect = 1.027e-9
Identity = 96/406 (23.65%), Postives = 168/406 (41.38%), Query Frame = 1
Query: 1279 TYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTI-VIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSR--NLQHPINQWQKS------ETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSIN---------LIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMT--ELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWD 2433
            +Y ++DL PY+ Y + V A   T+    P  +I V++T E  PS+P ++  A   + TS+ + W  P  ANG +  Y VY  R  N +  + +  K       ++++++  +  L  N  Y  ++NA N  G G  SE   II + G+PP+        I S S++         + W  P++      ++    +    G   P    K + +    D TD   T   LW   +Y + LAA    G   + T  + T    P+  PI +    +    I + WR   + + + +    K I L +++   +  E     Q VPA +   S  +E    ++     +K+   ++   G  +P +   +   P  +V  PP N+R+      T        A + WD
Sbjct:  710 SYVLSDLLPYSSYEITVAA--STMDGYGPESSIRVVKTLEDVPSAP-RNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQ-GIPPE-----APEIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQG--YPDSYVKAKTV----DGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYEVMK-GKIVVSWRPPSEEKRNGNITSYKAI-LSAMDATADRYE-----QPVPAPST--SSTFEV---NVRRAYLFKVAAATMKGIGPYSPVL--TINPDPAALV-GPPTNVRVEATSNST--------AVVQWD 1077          

HSP 6 Score: 55.4546 bits (132), Expect = 5.614e-7
Identity = 79/294 (26.87%), Postives = 127/294 (43.20%), Query Frame = 1
Query: 2653 LEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLV-ENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLP-DPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVT-MVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRD-LSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFV-----DKYIKF 3507
            +E    V  +E  P   PV+I ++ +TS SV I+W+PP   E  N  +VNY++ Y + G +++  +T  T     +I+GL     Y F VR+   VG G  S  V  +T    P   P++ +A  +N + I V W      N  + G+K+YY    +   I      D      M T+  ++ +S Y V + ++  +    L + +  A    +P     L+V +L      R M++ W KP     +  + V  N        T + EK  +   P E   V     DKY  F
Sbjct:  327 IEATTTVIAKELPPP--PVNIVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKY-SEG-RSSRGKTMETLENSLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDS----RRMQLTWDKPLYSSPVVGYTVRYN--------TSDGEKELTLTSPHEKHVVTGLHPDKYYYF 604          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8])

HSP 1 Score: 686.411 bits (1770), Expect = 0.000e+0
Identity = 327/626 (52.24%), Postives = 430/626 (68.69%), Query Frame = 1
Query: 4354 VPLSHS--NGI--VTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHN-RTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +P SHS  NG   V     S+ +N  N     HP +P   LA++I  L+ N+NA F  E+ESI+ G HFTW  S+ ++NK KNRYANV AYDHSRVVLS +   PG DYINANY DGY K  +YIATQGPLPETF  FWRMVWE +   IVM+T LEER RVKCDQYWP+RG+  Y +  + +  LE+V LA+YTMR   L  K+  +P    E R++ H Q+T WPDHGVPD   P L+F+KRV++  P+D+GPI+ HCSAG+GRTGA+IV+D  L +++++  VD+YG V+ LRAQR+YMVQTEEQY+FI+DA+L+A   G+TEV    LH H+  L Q        PS    +G+++EF+HL+ L     +   ANLP NR KNR+++ +PY++ RV ++ +   DGSDYINAS+IDGY+ + AYIATQ P   T  DFWR +W+HNS I+ ML +  E G+E+CS YWP E     G ++VEPM EY+M  + LREFR+  SD  T   RT+RQF F++W + G P + +  +DF+ QVH T  QFG  GPITVHC +G GRT VF+ALSI+LDRMR+E  VD+F TV+LLR +R  M+Q  +QY F YL A EYL+++D F
Sbjct: 1640 LPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGD--IEVTLLESVHLAHYTMRTMRL--KMVGEP----EVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ--------PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRI--SDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYDNF 2247          

HSP 2 Score: 107.842 bits (268), Expect = 7.993e-23
Identity = 90/317 (28.39%), Postives = 143/317 (45.11%), Query Frame = 1
Query:  250 AKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM------KKYVIPIPSGL-MLRIPDVKLTDGKPV---RIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRR----TMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHR-PQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDK---ESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWE 1146
            A+++V P S TV+      FFC+ DGNP   +    NG       +  +  + +GL  LR   V L D   V     D  V NP   E   A L V  P   +P GFP+ +L       + G+   ++C V G    K  W +D  PLD+    R    T+   G++      +ED G YEC A N +G   S    L ++   + P + ++  +   V  G  +NLTC A G P P++ W       ++D +     +++L LT +    ++ C A +++G I+    V  K++P  PVNI   ++      I+W+
Sbjct:   92 ARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFERVSLDDNATVVSCSADNGVANPVVAE---ASLTVV-PRDKVPIGFPQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWKKTDLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWK 404          

HSP 3 Score: 103.605 bits (257), Expect = 1.384e-21
Identity = 140/584 (23.97%), Postives = 245/584 (41.95%), Query Frame = 1
Query: 1384 ETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNL-QHPINQWQKSETTRQH--VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVP-NSPIGIDVRTLSPTSIAIRWR-------KGMDNEESISSFKIKVIKLKSIETV-------DNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIR-HNLVGPQNLIE-SLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMN-TADIGLEVKLNVSTR---ESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTI--RTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPD-PPINIEASRINENQIKVTW 3051
            +TK   P++ P S  A +    SI VKW P  + NG IT Y VYY+ +L   PI +W++ +         I  L  ++ Y ++V A NS G  P+S    +  R G+P QP       + S  + L W  P   S +V                   ++ E+E+ +      + +T L P+  Y+  +AA ++ G G  +  M  +T   +P +SP  +     S  S+ IRW+        G+     I+ F+++  K  ++E+V       D+S+ +      VP      SD   Y+++DL    +Y+I + +    G        +VKT     VPS P N    +L   T   LT       WD P  ++G +  Y +    +V  + ++E   K+R + ++   K         E   L     Y F + A N   D     + ++ T+     AP+   VS+D          I W+ P ++ +   +  Y +     G  ++ +  +T    +L   I GL   ++Y   + A  + G+   +++    T V  PD  PI+++   + + +I V+W
Sbjct:  498 QTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGYTVRY-----------NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVP------SDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLED--VPSAPRNFNA-ELTSATSVKLT-------WDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRY------FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLD-RDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATET-IATPVGSPDGEPIDVQY-EVMKGKIVVSW 1045          

HSP 4 Score: 90.1225 bits (222), Expect = 2.142e-17
Identity = 195/934 (20.88%), Postives = 352/934 (37.69%), Query Frame = 1
Query: 1288 VTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVP-PQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEE--------------IKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNV-RTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKL------------KSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIIN-DLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIR---TTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFR-TVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPK-DIESCNTLDV------GPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKV-RSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYL-RILRVTEHLGIIRTYYLII-------EESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNISFWVGQDIWRSQY 3939
            +  L P +RY V+VIA   + GDS  S  + + T++  P  PP       D+   + + W  P+ ++  +  Y V Y  N      +   +    +HV +T L  +  Y+ +V A +  G G  +EP        +P   P     A  +S S+ + W  P Q     VL  Y + Y  +       L + E +              + +  D T Y +++L P + Y I++AA T  G G  +++ V +T   VP++P   +    S TS+ + W        ++  + + + ++            K I  + +S++ + ++ S+   T+    +  +  N D E  +   I+   +      AP I  +   R       PP+  R+     K +   T +     W   + + G   +Y                        V  K V GT+  T    L  G VY+  +AA N           ++T   +PD  P+ +    +    + +SW+PP  E  NG + +Y+       +  T  R       P+  +  E +     Y F+V A T  G GP+S  +        L  PP N+     + +   V W+       K   F + Y  +   + D E    L V       P     + ++  +  Y   + +   +NR G  S+  T   S  P      V +L+   K   S+++ W+     +    F V   G   Y     + +   +    ++VD  +K+ +++    ++ P+M+Y I V       G   ++   Q     T    P FV  P+++  + T     + R+   TE  G I  Y++I+       E+ ++       K + E     ++ +S SP      S  + +K S     VG D   + Y
Sbjct:  568 INGLEPDSRYFVRVIA-QNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDS-RRMQLTWDKPLYSS-PVVGYTVRY--NTSDGEKELTLTSPHEKHV-VTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPE---APEIVSVSLDRD-----EPPVVARIEWKMPKMKPNETPIEKYNLW---LRAQGYPDSY------------------------VKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYE-VMKGKIVVSWRPPSEEKRNGNITSYKA--ILSAMDATADRYEQPVPAPSTSSTFE-VNVRRAYLFKVAAATMKGIGPYSPVLTINPDPAALVGPPTNVRVEATSNSTAVVQWDFESQ---KADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLAVK-NNRQGPCSDPPTVLESVTPT---YMVQNLRVLWKTSNSVQLTWEYNGPRN--VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD--EKHREYL--WTNLRPHMMYTIHVGVRTLPPGARKYWP--QEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSP------SKKLKRKASE----VGDDSQSASY 1431          

HSP 5 Score: 65.4698 bits (158), Expect = 5.719e-10
Identity = 133/580 (22.93%), Postives = 237/580 (40.86%), Query Frame = 1
Query: 1279 TYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTI-VIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSR--NLQHPINQWQKS------ETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSIN---------LIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMT--ELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPV-SIDITGITSHSVNISWQPPLVENHNGILVNY--QVAYFTYGLKNTTIRTTSTPNLYALIE---------GLQENMLYTFQV 2919
            +Y ++DL PY+ Y + V A   T+    P  +I V++T E  PS+P ++  A   + TS+ + W  P  ANG +  Y VY  R  N +  + +  K       ++++++  +  L  N  Y  ++NA N  G G  SE   II + G+PP+        I S S++         + W  P++      ++    +    G   P    K + +    D TD   T   LW   +Y + LAA    G   + T  + T    P+  PI +    +    I + WR   + + + +    K I L +++   +  E     Q VPA +   S  +E    ++     +K+   ++   G  +P +   +   P  +V  PP N+R+      T        A + WD          ++ +++ +  P N +++ K + L V   +K            +L   K Y F V A+     G       +  ES   +Y V ++ +   TS+SV ++W+     N  G  VN+  +  Y  + L+    +T STP     ++          L+ +M+YT  V
Sbjct:  778 SYVLSDLLPYSSYEITVAA--STMDGYGPESSIRVVKTLEDVPSAP-RNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQ-GIPPE-----APEIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQG--YPDSYVKAKTV----DGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYEVMK-GKIVVSWRPPSEEKRNGNITSYKAI-LSAMDATADRYE-----QPVPAPST--SSTFEV---NVRRAYLFKVAAATMKGIGPYSPVL--TINPDPAALV-GPPTNVRVEATSNST--------AVVQWD---FESQKADSFVVKY-MHEPGNRMDTEKWKQLPVVSIDKE--NPKRFAVVSDLNAHKPYAFCVLAVKNNRQG-PCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRN-VGFYVNHTGRKDYVNHELQE---KTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHV 1308          

HSP 6 Score: 64.6994 bits (156), Expect = 9.233e-10
Identity = 95/417 (22.78%), Postives = 160/417 (38.37%), Query Frame = 1
Query: 1924 YHISLAARTEHGVGVSNT-MNVRTENRVP-NSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVS-TRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYF----------------------TYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIY 3099
            Y  ++ +    GVG+ +  +  +T+   P  +P+    R+L+  SI ++W         I+ +K+             +N++         +   +SD +   IN LE    Y + + +  S G S       V TR G  +P  P  + +  L  +           + WD P+ S   +  Y +R+N        +  K  +L+    +  VTG         L   K Y F VAA +    G   +  +S T  S P S P  +     +S SV I W+ P  +  NG+L  Y++ YF                      +  L   ++   S    Y L + L  +  Y   V A T  G GP SS    +T+  +P  P N  A   +   +K+TW+     N  ++G+ +Y
Sbjct:  476 YEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYY-----------TNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQG--IPGQPPMLTVKALDSRR--------MQLTWDKPLYSSPVV-GYTVRYNTS------DGEKELTLTSPHEKHVVTG---------LHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSS-YEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVY 854          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8])

HSP 1 Score: 686.026 bits (1769), Expect = 0.000e+0
Identity = 327/626 (52.24%), Postives = 430/626 (68.69%), Query Frame = 1
Query: 4354 VPLSHS--NGI--VTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHN-RTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +P SHS  NG   V     S+ +N  N     HP +P   LA++I  L+ N+NA F  E+ESI+ G HFTW  S+ ++NK KNRYANV AYDHSRVVLS +   PG DYINANY DGY K  +YIATQGPLPETF  FWRMVWE +   IVM+T LEER RVKCDQYWP+RG+  Y +  + +  LE+V LA+YTMR   L  K+  +P    E R++ H Q+T WPDHGVPD   P L+F+KRV++  P+D+GPI+ HCSAG+GRTGA+IV+D  L +++++  VD+YG V+ LRAQR+YMVQTEEQY+FI+DA+L+A   G+TEV    LH H+  L Q        PS    +G+++EF+HL+ L     +   ANLP NR KNR+++ +PY++ RV ++ +   DGSDYINAS+IDGY+ + AYIATQ P   T  DFWR +W+HNS I+ ML +  E G+E+CS YWP E     G ++VEPM EY+M  + LREFR+  SD  T   RT+RQF F++W + G P + +  +DF+ QVH T  QFG  GPITVHC +G GRT VF+ALSI+LDRMR+E  VD+F TV+LLR +R  M+Q  +QY F YL A EYL+++D F
Sbjct: 1616 LPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGD--IEVTLLESVHLAHYTMRTMRL--KMVGEP----EVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ--------PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRI--SDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYDNF 2223          

HSP 2 Score: 184.496 bits (467), Expect = 4.435e-46
Identity = 238/980 (24.29%), Postives = 411/980 (41.94%), Query Frame = 1
Query:  250 AKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM------KKYVIPIPSGL-MLRIPDVKLTDGKPV---RIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRR----TMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHR-PQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDK---ESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNL-QHPINQWQKSETTRQH--VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVP-NSPIGIDVRTLSPTSIAIRWR-------KGMDNEESISSFKIKVIKLKSIETV-------DNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHN-LVGPQNLIE-SLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMN-TADIGLEVKLNVSTR---ESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTI--RTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPD-PPINIEASRINENQIKVTW 3051
            A+++V P S TV+      FFC+ DGNP   +    NG       +  +  + +GL  LR   V L D   V     D  V NP   E   A L V  P   +P GFP+ +L       + G+   ++C V G    K  W +D  PLD+    R    T+   G++      +ED G YEC A N +G   S    L ++   + P + ++  +   V  G  +NLTC A G P P++ W       ++D +     +++L LT +    ++ C A +++G I+    V  K++P  PVNI   ++      I+W+  P+ +     + +        N  L   +  +      +    +  +  L  +  Y   V + +  +G    S  +  +TK   P++ P S  A +    SI VKW P  + NG IT Y VYY+ +L   PI +W++ +         I  L  ++ Y ++V A NS G  P+S    +  R G+P QP       + S  + L W  P   S +V                   ++ E+E+ +      + +T L P+  Y+  +AA ++ G G  +  M  +T   +P +SP  +     S  S+ IRW+        G+     I+ F+++  K  ++E+V       D+S+ +      VP      SD   Y+++DL    +Y+I + +    G        +VKT     VPS P N    +L   T   LT       WD P  ++G +  Y +  + +V  + ++E   K+R + ++   K         E   L     Y F + A N   D     + ++ T+     AP+   VS+D          I W+ P ++ +   +  Y +     G  ++ +  +T    +L   I GL   ++Y   + A  + G+   +++    T V  PD  PI+++   + + +I V+W
Sbjct:   92 ARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFERVSLDDNATVVSCSADNGVANPVVAE---ASLTVV-PRDKVPIGFPQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWKKTDLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWKP-PKYNEAINKYVV--------NYRLKYSEGRSSRGKTMETLENSLVIDGLVAFQTYEFTVRS-AGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGYTVRY-----------NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVP------SDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLED--VPSAPRNFNA-ELTSATSVKLT-------WDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRY------FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLD-RDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATET-IATPVGSPDGEPIDVQY-EVMKGKIVVSW 1021          

HSP 3 Score: 89.7373 bits (221), Expect = 2.615e-17
Identity = 195/934 (20.88%), Postives = 352/934 (37.69%), Query Frame = 1
Query: 1288 VTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVP-PQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEE--------------IKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNV-RTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKL------------KSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIIN-DLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIR---TTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFR-TVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPK-DIESCNTLDV------GPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKV-RSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYL-RILRVTEHLGIIRTYYLII-------EESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNISFWVGQDIWRSQY 3939
            +  L P +RY V+VIA   + GDS  S  + + T++  P  PP       D+   + + W  P+ ++  +  Y V Y  N      +   +    +HV +T L  +  Y+ +V A +  G G  +EP        +P   P     A  +S S+ + W  P Q     VL  Y + Y  +       L + E +              + +  D T Y +++L P + Y I++AA T  G G  +++ V +T   VP++P   +    S TS+ + W        ++  + + + ++            K I  + +S++ + ++ S+   T+    +  +  N D E  +   I+   +      AP I  +   R       PP+  R+     K +   T +     W   + + G   +Y                        V  K V GT+  T    L  G VY+  +AA N           ++T   +PD  P+ +    +    + +SW+PP  E  NG + +Y+       +  T  R       P+  +  E +     Y F+V A T  G GP+S  +        L  PP N+     + +   V W+       K   F + Y  +   + D E    L V       P     + ++  +  Y   + +   +NR G  S+  T   S  P      V +L+   K   S+++ W+     +    F V   G   Y     + +   +    ++VD  +K+ +++    ++ P+M+Y I V       G   ++   Q     T    P FV  P+++  + T     + R+   TE  G I  Y++I+       E+ ++       K + E     ++ +S SP      S  + +K S     VG D   + Y
Sbjct:  544 INGLEPDSRYFVRVIA-QNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDS-RRMQLTWDKPLYSS-PVVGYTVRY--NTSDGEKELTLTSPHEKHV-VTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPE---APEIVSVSLDRD-----EPPVVARIEWKMPKMKPNETPIEKYNLW---LRAQGYPDSY------------------------VKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYE-VMKGKIVVSWRPPSEEKRNGNITSYKA--ILSAMDATADRYEQPVPAPSTSSTFE-VNVRRAYLFKVAAATMKGIGPYSPVLTINPDPAALVGPPTNVRVEATSNSTAVVQWDFESQ---KADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLAVK-NNRQGPCSDPPTVLESVTPT---YMVQNLRVLWKTSNSVQLTWEYNGPRN--VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD--EKHREYL--WTNLRPHMMYTIHVGVRTLPPGARKYWP--QEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSP------SKKLKRKASE----VGDDSQSASY 1407          

HSP 4 Score: 65.4698 bits (158), Expect = 6.423e-10
Identity = 133/580 (22.93%), Postives = 237/580 (40.86%), Query Frame = 1
Query: 1279 TYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTI-VIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSR--NLQHPINQWQKS------ETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSIN---------LIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMT--ELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPV-SIDITGITSHSVNISWQPPLVENHNGILVNY--QVAYFTYGLKNTTIRTTSTPNLYALIE---------GLQENMLYTFQV 2919
            +Y ++DL PY+ Y + V A   T+    P  +I V++T E  PS+P ++  A   + TS+ + W  P  ANG +  Y VY  R  N +  + +  K       ++++++  +  L  N  Y  ++NA N  G G  SE   II + G+PP+        I S S++         + W  P++      ++    +    G   P    K + +    D TD   T   LW   +Y + LAA    G   + T  + T    P+  PI +    +    I + WR   + + + +    K I L +++   +  E     Q VPA +   S  +E    ++     +K+   ++   G  +P +   +   P  +V  PP N+R+      T        A + WD          ++ +++ +  P N +++ K + L V   +K            +L   K Y F V A+     G       +  ES   +Y V ++ +   TS+SV ++W+     N  G  VN+  +  Y  + L+    +T STP     ++          L+ +M+YT  V
Sbjct:  754 SYVLSDLLPYSSYEITVAA--STMDGYGPESSIRVVKTLEDVPSAP-RNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQ-GIPPE-----APEIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQG--YPDSYVKAKTV----DGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYEVMK-GKIVVSWRPPSEEKRNGNITSYKAI-LSAMDATADRYE-----QPVPAPST--SSTFEV---NVRRAYLFKVAAATMKGIGPYSPVL--TINPDPAALV-GPPTNVRVEATSNST--------AVVQWD---FESQKADSFVVKY-MHEPGNRMDTEKWKQLPVVSIDKE--NPKRFAVVSDLNAHKPYAFCVLAVKNNRQG-PCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRN-VGFYVNHTGRKDYVNHELQE---KTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHV 1284          

HSP 5 Score: 64.6994 bits (156), Expect = 9.376e-10
Identity = 95/417 (22.78%), Postives = 160/417 (38.37%), Query Frame = 1
Query: 1924 YHISLAARTEHGVGVSNT-MNVRTENRVP-NSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVS-TRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYF----------------------TYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIY 3099
            Y  ++ +    GVG+ +  +  +T+   P  +P+    R+L+  SI ++W         I+ +K+             +N++         +   +SD +   IN LE    Y + + +  S G S       V TR G  +P  P  + +  L  +           + WD P+ S   +  Y +R+N        +  K  +L+    +  VTG         L   K Y F VAA +    G   +  +S T  S P S P  +     +S SV I W+ P  +  NG+L  Y++ YF                      +  L   ++   S    Y L + L  +  Y   V A T  G GP SS    +T+  +P  P N  A   +   +K+TW+     N  ++G+ +Y
Sbjct:  452 YEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYY-----------TNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQG--IPGQPPMLTVKALDSRR--------MQLTWDKPLYSSPVV-GYTVRYNTS------DGEKELTLTSPHEKHVVTG---------LHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSS-YEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVY 830          

HSP 6 Score: 55.8398 bits (133), Expect = 4.556e-7
Identity = 79/294 (26.87%), Postives = 127/294 (43.20%), Query Frame = 1
Query: 2653 LEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLV-ENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLP-DPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDV-GPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRD-LSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFV-----DKYIKF 3507
            +E    V  +E  P   PV+I ++ +TS SV I+W+PP   E  N  +VNY++ Y + G +++  +T  T     +I+GL     Y F VR+   VG G  S  V  +T    P   P++ +A  +N + I V W      N  + G+K+YY    +   I      D      M T+  ++ +S Y V + ++  +    L + +  A    +P     L+V +L      R M++ W KP     +  + V  N        T + EK  +   P E   V     DKY  F
Sbjct:  371 IEATTTVIAKELPPP--PVNIVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKY-SEG-RSSRGKTMETLENSLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDS----RRMQLTWDKPLYSSPVVGYTVRYN--------TSDGEKELTLTSPHEKHVVTGLHPDKYYYF 648          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0305950)

HSP 1 Score: 1120.53 bits (2897), Expect = 0.000e+0
Identity = 725/2040 (35.54%), Postives = 1075/2040 (52.70%), Query Frame = 1
Query:  226 HLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMK------KY-VIPIPSGL-MLRIPDVKLT-DGKPVRIDCIVRNPSAEE-KKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDV-EVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGK-HIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAY---FTYGL---KNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEII-LVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSK-----YSFESLQSASKPIS-YSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACI------------FTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            H+NP     +II  PQ+Q V +G  A F+C   G+P   +    NG K      +Y V+  P G+ +LRI  V+   D  P   +C+  N   +     A L + +  K  P GFP         V +VG  + M C   G       W K+   +D+S PR + L+ G +  +   +ED G YEC A N +G+  S    L ++   + P +   P+ + EV  G  +NL+C A G+P P ++W+  ++   P N++    ++L L +I E A+Y C A +++G I     V+V+ +P  P ++    +  T  ++ W      DL        +      N      +I  I         + Y V  L PYT Y   VIA +  +G   PS      T E    S P++V     + +++ + W PP   NG++T Y VYY+ N   P   W         +  +++L  +  Y ++V A  S G GP+S P  +  + GVP QP NFR   I  T++ L W+ P   S+ ++   +      + + H   ++N E           Y +  L+P+TLY+I LAAR++ G G +   + VRT+  VP  P  +    L+ TSI + W+  ++ + +  I  + I   +L+  E     NE        P K  +  D  E+ +  L+    Y I + ++   G        +VKT PG +   P +++++ +          ++  ++ W+ P  ++G +R YR+R  +       ++LK   LS     K          F  L  G  YEF VA  N   IG E      T E  P   P +I I   T   + ++W PP  E+ NGI+  Y V +     +GL   +N T+R        A+   L+EN  Y F+VRA+TK G GP+S  +   T   +   P++++A   +E   ++ WE   T+  K++G+KI+Y +  + +D++   T  VG      L N++  + Y V I ++   N  G +S   T +I    V  +L    +       SM + W  P     ++ ++++ +    +    G  +   +   P+    +  Y+K    + ++SP   Y+++V  +         Y      +  T MA P+ +  P+   +VN   + + L   + +E  G I  YYL++   +   K+N  K      + + L   +KP    +P + A+F     ++    +F +G       +      T+  L R      +K Y++F+RA +            F+E  S    +  P  +       N+   P ++    K + ++    ++  ++    I   ++ V C +KRRR  +   +P +  +      +  + +   +GP    P+        DM    + NF+   +  HPPIP    A++I  LK+NDN KF++EYESI+PG  FTW  SNLE NK KNRYANV AYDHSRV L  +  + GSDYINANYCDGYRK NAY+ATQGPL ETF  FWRM WE + A IVMMT+LEER R+KCDQYWPTRG+E Y +  ++I   ET ELA Y++R F L ++      G  + R++   QFT WPDHGVPD   P L F++R R+  P +SGP++VHCSAGVGRTG YIV+DS L +++HEK++D+YG V+ LRAQRNYMVQTE+QY+FI+DA+LEA +CG TEV  R+LH H+ KL        +T   +  +GME+EFK LS +     +F TANLP N+ KNRL++ILPYE+ RV L PI   +GSDY+NASFIDGYR + AYIA QGP+ +   DFWRMLW+HNS+IVVML++L+EMGREKC QYWP ERS  +   +V+P+ EYNMP + LREF+V  +  +  +RT+RQFQF+DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGR+GVF+ LSIVL+RM+ EG +D+FQTVR+LR QRP MVQTEDQY FCY  ALEYL SFD +
Sbjct:   14 HVNP----PEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISILRIEPVRAGRDDAP--YECVAENGVGDAVSADATLTIYEGDK-TPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL-----QYYVIQYKPKNANQAFSEISGI-------ITMYYVVRALSPYTEYEFYVIAVNN-IGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHKRISNSEA----------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRD-EGKGFLNE--------PFKF-DVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKT-PGGVPVRPTVSLKIMERE-------PIVSIELEWERPAQTYGELRGYRLRWGVKD-----QALKEEMLSGPQMTKK--------RFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRK-------AVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLLGYKIFYTMTAV-EDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAAR-FKNGLGRLSEKVTVRIKPEDVPLNLRAHDVS----THSMTLSWSPPIRLTPVN-YKISFDAMKVFVDSQGFSQ---TQIVPKREIILKHYVK-THTINELSPFTTYNVNVSAI----PSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILP--QASEEYGPISHYYLVV---VPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFP----QRSIPFTFHLGSGDDYHNF------TNRKLER------EKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREA-PPGERPHRPDPNWPAEPEVSVNRNKDEPEIL--WVVLPLMVSTFIVSTALIVLCVVKRRR--QPCKTPDQAAVT-----RPLMAADLGAGPTPSDPV--------DMR---RLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTIT--ETQELATYSIRTFQLCRQ------GFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLL-------ITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDA-RDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNY 1910          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0331241)

HSP 1 Score: 1112.83 bits (2877), Expect = 0.000e+0
Identity = 721/2031 (35.50%), Postives = 1071/2031 (52.73%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMK------KY-VIPIPSGL-MLRIPDVKLT-DGKPVRIDCIVRNPSAEE-KKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDV-EVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGK-HIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAY---FTYGL---KNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEII-LVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSK-----YSFESLQSASKPIS-YSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACI------------FTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +II  PQ+Q V +G  A F+C   G+P   +    NG K      +Y V+  P G+ +LRI  V+   D  P   +C+  N   +     A L + +  K  P GFP         V +VG  + M C   G       W K+   +D+S PR + L+ G +  +   +ED G YEC A N +G+  S    L ++   + P +   P+ + EV  G  +NL+C A G+P P ++W+  ++   P N++    ++L L +I E A+Y C A +++G I     V+V+ +P  P ++    +  T  ++ W      DL        +      N      +I  I         + Y V  L PYT Y   VIA +  +G   PS      T+     S P++V     + +++ + W PP   NG++T Y VYY+ N   P   W         +  +++L  +  Y ++V A  S G GP+S P  +  + GVP QP NFR   I  T++ L W+ P   S+ ++   +      + + H   ++N E           Y +  L+P+TLY+I LAAR++ G G +   + VRT+  VP  P  +    L+ TSI + W+  ++ + +  I  + I   +L+  E     NE        P K  +  D  E+ +  L+    Y I + ++   G        +VKT PG +   P +++++ +          ++  ++ W+ P  ++G +R YR+R  +       ++LK   LS     K          F  L  G  YEF VA  N   IG E      T E  P   P +I I   T   + ++W PP  E+ NGI+  Y V +     +GL   +N T+R        A+   L+EN  Y F+VRA+TK G GP+S  +   T   +   P++++A   +E   ++ WE   T+  K++G+KI+Y +  + +D++   T  VG      L N++  + Y V I ++   N  G +S   T +I    V  +L    +       SM + W  P     ++ ++++ +    +    G  +   +   P+    +  Y+K    + ++SP   Y+++V  +         Y      +  T MA P+ +  P+   +VN   + + L   + +E  G I  YYL++   +   K+N  K      + + L   +KP    +P + A+F     ++    +F +G       +      T+  L R      +K Y++F+RA +            F+E  S    +  P  +       N+   P ++    K + ++    ++  ++    I   ++ V C +KRRR  +   +P +  +      +  + +   +GP    P+        DM    + NF+   +  HPPIP    A++I  LK+NDN KF++EYESI+PG  FTW  SNLE NK KNRYANV AYDHSRV L  +  + GSDYINANYCDGYRK NAY+ATQGPL ETF  FWRM WE + A IVMMT+LEER R+KCDQYWPTRG+E Y +  ++I   ET ELA Y++R F L ++      G  + R++   QFT WPDHGVPD   P L F++R R+  P +SGP++VHCSAGVGRTG YIV+DS L +++HEK++D+YG V+ LRAQRNYMVQTE+QY+FI+DA+LEA +CG TEV  R+LH H+ KL        +T   +  +GME+EFK LS +     +F TANLP N+ KNRL++ILPYE+ RV L PI   +GSDY+NASFIDGYR + AYIA QGP+ +   DFWRMLW+HNS+IVVML++L+EMGREKC QYWP ERS  +   +V+P+ EYNMP + LREF+V  +  +  +RT+RQFQF+DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGR+GVF+ LSIVL+RM+ EG +D+FQTVR+LR QRP MVQTEDQY FCY  ALEYL SFD +
Sbjct:   37 EIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISILRIEPVRAGRDDAP--YECVAENGVGDAVSADATLTIYEGDK-TPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL-----QYYVIQYKPKNANQAFSEISGI-------ITMYYVVRALSPYTEYEFYVIAVNN-IGRGPPSAPATCTTEM---ESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHKRISNSEA----------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRD-EGKGFLNE--------PFKF-DVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKT-PGGVPVRPTVSLKIMERE-------PIVSIELEWERPAQTYGELRGYRLRWGVKD-----QALKEEMLSGPQMTKK--------RFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRK-------AVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLLGYKIFYTMTAV-EDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAAR-FKNGLGRLSEKVTVRIKPEDVPLNLRAHDVS----THSMTLSWSPPIRLTPVN-YKISFDAMKVFVDSQGFSQ---TQIVPKREIILKHYVK-THTINELSPFTTYNVNVSAI----PSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILP--QASEEYGPISHYYLVV---VPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFP----QRSIPFTFHLGSGDDYHNF------TNRKLER------EKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREA-PPGERPHRPDPNWPAEPEVSVNRNKDEPEIL--WVVLPLMVSTFIVSTALIVLCVVKRRR--QPCKTPDQAAVT-----RPLMAADLGAGPTPSDPV--------DMR---RLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTIT--ETQELATYSIRTFQLCRQ------GFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLL-------ITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDA-RDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNY 1925          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0331242)

HSP 1 Score: 1112.06 bits (2875), Expect = 0.000e+0
Identity = 721/2031 (35.50%), Postives = 1071/2031 (52.73%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMK------KY-VIPIPSGL-MLRIPDVKLT-DGKPVRIDCIVRNPSAEE-KKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDV-EVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGK-HIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAY---FTYGL---KNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEII-LVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSK-----YSFESLQSASKPIS-YSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACI------------FTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +II  PQ+Q V +G  A F+C   G+P   +    NG K      +Y V+  P G+ +LRI  V+   D  P   +C+  N   +     A L + +  K  P GFP         V +VG  + M C   G       W K+   +D+S PR + L+ G +  +   +ED G YEC A N +G+  S    L ++   + P +   P+ + EV  G  +NL+C A G+P P ++W+  ++   P N++    ++L L +I E A+Y C A +++G I     V+V+ +P  P ++    +  T  ++ W      DL        +      N      +I  I         + Y V  L PYT Y   VIA +  +G   PS      T+     S P++V     + +++ + W PP   NG++T Y VYY+ N   P   W         +  +++L  +  Y ++V A  S G GP+S P  +  + GVP QP NFR   I  T++ L W+ P   S+ ++   +      + + H   ++N E           Y +  L+P+TLY+I LAAR++ G G +   + VRT+  VP  P  +    L+ TSI + W+  ++ + +  I  + I   +L+  E     NE        P K  +  D  E+ +  L+    Y I + ++   G        +VKT PG +   P +++++ +          ++  ++ W+ P  ++G +R YR+R  +       ++LK   LS     K          F  L  G  YEF VA  N   IG E      T E  P   P +I I   T   + ++W PP  E+ NGI+  Y V +     +GL   +N T+R        A+   L+EN  Y F+VRA+TK G GP+S  +   T   +   P++++A   +E   ++ WE   T+  K++G+KI+Y +  + +D++   T  VG      L N++  + Y V I ++   N  G +S   T +I    V  +L    +       SM + W  P     ++ ++++ +    +    G  +   +   P+    +  Y+K    + ++SP   Y+++V  +         Y      +  T MA P+ +  P+   +VN   + + L   + +E  G I  YYL++   +   K+N  K      + + L   +KP    +P + A+F     ++    +F +G       +      T+  L R      +K Y++F+RA +            F+E  S    +  P  +       N+   P ++    K + ++    ++  ++    I   ++ V C +KRRR  +   +P +  +      +  + +   +GP    P+        DM    + NF+   +  HPPIP    A++I  LK+NDN KF++EYESI+PG  FTW  SNLE NK KNRYANV AYDHSRV L  +  + GSDYINANYCDGYRK NAY+ATQGPL ETF  FWRM WE + A IVMMT+LEER R+KCDQYWPTRG+E Y +  ++I   ET ELA Y++R F L ++      G  + R++   QFT WPDHGVPD   P L F++R R+  P +SGP++VHCSAGVGRTG YIV+DS L +++HEK++D+YG V+ LRAQRNYMVQTE+QY+FI+DA+LEA +CG TEV  R+LH H+ KL        +T   +  +GME+EFK LS +     +F TANLP N+ KNRL++ILPYE+ RV L PI   +GSDY+NASFIDGYR + AYIA QGP+ +   DFWRMLW+HNS+IVVML++L+EMGREKC QYWP ERS  +   +V+P+ EYNMP + LREF+V  +  +  +RT+RQFQF+DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGR+GVF+ LSIVL+RM+ EG +D+FQTVR+LR QRP MVQTEDQY FCY  ALEYL SFD +
Sbjct:   51 EIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISILRIEPVRAGRDDAPY--ECVAENGVGDAVSADATLTIYEGDK-TPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL-----QYYVIQYKPKNANQAFSEISGI-------ITMYYVVRALSPYTEYEFYVIAVNN-IGRGPPSAPATCTTEM---ESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHKRISNSEA----------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRD-EGKGFLNE--------PFKF-DVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKT-PGGVPVRPTVSLKIMERE-------PIVSIELEWERPAQTYGELRGYRLRWGVKD-----QALKEEMLSGPQMTKK--------RFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRK-------AVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLLGYKIFYTMTAV-EDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAAR-FKNGLGRLSEKVTVRIKPEDVPLNLRAHDVS----THSMTLSWSPPIRLTPVN-YKISFDAMKVFVDSQGFSQ---TQIVPKREIILKHYVK-THTINELSPFTTYNVNVSAI----PSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILP--QASEEYGPISHYYLVV---VPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFP----QRSIPFTFHLGSGDDYHNF------TNRKLER------EKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREA-PPGERPHRPDPNWPAEPEVSVNRNKDEPEIL--WVVLPLMVSTFIVSTALIVLCVVKRRR--QPCKTPDQAAVT-----RPLMAADLGAGPTPSDPV--------DMR---RLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTIT--ETQELATYSIRTFQLCRQ------GFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLL-------ITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDA-RDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNY 1939          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0331240)

HSP 1 Score: 1110.9 bits (2872), Expect = 0.000e+0
Identity = 721/2036 (35.41%), Postives = 1071/2036 (52.60%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMK------KY-VIPIPSGL-MLRIPDVKLT-DGKPVRIDCIVRNPSAEE-KKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDV-EVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELP-----PSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGK-HIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAY---FTYGL---KNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEII-LVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSK-----YSFESLQSASKPIS-YSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACI------------FTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +II  PQ+Q V +G  A F+C   G+P   +    NG K      +Y V+  P G+ +LRI  V+   D  P   +C+  N   +     A L + +  K  P GFP         V +VG  + M C   G       W K+   +D+S PR + L+ G +  +   +ED G YEC A N +G+  S    L ++   + P +   P+ + EV  G  +NL+C A G+P P ++W+  ++   P N++    ++L L +I E A+Y C A +++G I     V+V+ +P  P ++    +  T  ++ W      DL        +      N      +I  I         + Y V  L PYT Y   VIA +  +G   PS      T +         S P++V     + +++ + W PP   NG++T Y VYY+ N   P   W         +  +++L  +  Y ++V A  S G GP+S P  +  + GVP QP NFR   I  T++ L W+ P   S+ ++   +      + + H   ++N E           Y +  L+P+TLY+I LAAR++ G G +   + VRT+  VP  P  +    L+ TSI + W+  ++ + +  I  + I   +L+  E     NE        P K  +  D  E+ +  L+    Y I + ++   G        +VKT PG +   P +++++ +          ++  ++ W+ P  ++G +R YR+R  +       ++LK   LS     K          F  L  G  YEF VA  N   IG E      T E  P   P +I I   T   + ++W PP  E+ NGI+  Y V +     +GL   +N T+R        A+   L+EN  Y F+VRA+TK G GP+S  +   T   +   P++++A   +E   ++ WE   T+  K++G+KI+Y +  + +D++   T  VG      L N++  + Y V I ++   N  G +S   T +I    V  +L    +       SM + W  P     ++ ++++ +    +    G  +   +   P+    +  Y+K    + ++SP   Y+++V  +         Y      +  T MA P+ +  P+   +VN   + + L   + +E  G I  YYL++   +   K+N  K      + + L   +KP    +P + A+F     ++    +F +G       +      T+  L R      +K Y++F+RA +            F+E  S    +  P  +       N+   P ++    K + ++    ++  ++    I   ++ V C +KRRR  +   +P +  +      +  + +   +GP    P+        DM    + NF+   +  HPPIP    A++I  LK+NDN KF++EYESI+PG  FTW  SNLE NK KNRYANV AYDHSRV L  +  + GSDYINANYCDGYRK NAY+ATQGPL ETF  FWRM WE + A IVMMT+LEER R+KCDQYWPTRG+E Y +  ++I   ET ELA Y++R F L ++      G  + R++   QFT WPDHGVPD   P L F++R R+  P +SGP++VHCSAGVGRTG YIV+DS L +++HEK++D+YG V+ LRAQRNYMVQTE+QY+FI+DA+LEA +CG TEV  R+LH H+ KL        +T   +  +GME+EFK LS +     +F TANLP N+ KNRL++ILPYE+ RV L PI   +GSDY+NASFIDGYR + AYIA QGP+ +   DFWRMLW+HNS+IVVML++L+EMGREKC QYWP ERS  +   +V+P+ EYNMP + LREF+V  +  +  +RT+RQFQF+DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGR+GVF+ LSIVL+RM+ EG +D+FQTVR+LR QRP MVQTEDQY FCY  ALEYL SFD +
Sbjct:   37 EIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISILRIEPVRAGRDDAP--YECVAENGVGDAVSADATLTIYEGDK-TPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL-----QYYVIQYKPKNANQAFSEISGI-------ITMYYVVRALSPYTEYEFYVIAVNN-IGRGPPSAPATCTTGDFSFGGTKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHKRISNSEA----------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRD-EGKGFLNE--------PFKF-DVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKT-PGGVPVRPTVSLKIMERE-------PIVSIELEWERPAQTYGELRGYRLRWGVKD-----QALKEEMLSGPQMTKK--------RFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRK-------AVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLLGYKIFYTMTAV-EDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAAR-FKNGLGRLSEKVTVRIKPEDVPLNLRAHDVS----THSMTLSWSPPIRLTPVN-YKISFDAMKVFVDSQGFSQ---TQIVPKREIILKHYVK-THTINELSPFTTYNVNVSAI----PSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILP--QASEEYGPISHYYLVV---VPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFP----QRSIPFTFHLGSGDDYHNF------TNRKLER------EKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREA-PPGERPHRPDPNWPAEPEVSVNRNKDEPEIL--WVVLPLMVSTFIVSTALIVLCVVKRRR--QPCKTPDQAAVT-----RPLMAADLGAGPTPSDPV--------DMR---RLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTIT--ETQELATYSIRTFQLCRQ------GFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLL-------ITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDA-RDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNY 1933          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0112800)

HSP 1 Score: 1102.43 bits (2850), Expect = 0.000e+0
Identity = 734/2121 (34.61%), Postives = 1087/2121 (51.25%), Query Frame = 1
Query:  226 HLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMK------KY-VIPIPSGL-MLRIPDVKLT-DGKPVRIDCIVRNPSAEE-KKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDV-EVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGK-HIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSP-IGIDVRTLSPTSIAIRW--------------------RKGMDNEESIS-----------------SFKIKVIKLKSIETVDNSNEMHVQIQS--------VPAKTKNQSDIYEYIINDLETGQNYKIVLWSV--------GSSGLSAPFIFDIVKTRPGNIV---PSPPLNIRLNQLRQKTESGLTLLLA--------------------------DIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAY---FTYGL---KNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEII-LVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSK-----YSFESLQSASKPIS-YSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACI------------FTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            H+NP     +II  PQ+Q V +G  A F+C   G+P   +    NG K      +Y V+  P G+ +LRI  V+   D  P   +C+  N   +     A L + +  K  P GFP         V +VG  + M C   G       W K+   +D+S PR + L+ G +  +   +ED G YEC A N +G+  S    L ++   + P +   P+ + EV  G  +NL+C A G+P P ++W+  ++   P N++    ++L L +I E A+Y C A +++G I     V+V+ +P  P ++    +  T  ++ W      DL        +      N      +I  I         + Y V  L PYT Y   VIA +  +G   PS      T E    S P++V     + +++ + W PP   NG++T Y VYY+ N   P   W         +  +++L  +  Y ++V A  S G GP+S P  +  + GVP QP NFR   I  T++ L W+ P   S+ ++   +      + + H   ++N E           Y +  L+P+TLY+I LAAR++ G G +   + VRT+  VP +P   I     S T+I++ W                      G +++E+ +                  +KI V+   S+     S+ + ++ Q         V A   N + I+      LE  +N  I  + +        G   L+ PF FD+V T   N+    P    +I++  L +K +   +  +                           ++ W+ P  ++G +R YR+R  +       ++LK   LS     K          F  L  G  YEF VA  N   IG E      T E  P   P +I I   T   + ++W PP  E+ NGI+  Y V +     +GL   +N T+R        A+   L+EN  Y F+VRA+TK G GP+S  +   T   +   P++++A   +E   ++ WE   T+  K++G+KI+Y +  + +D++   T  VG      L N++  + Y V I ++   N  G +S   T +I    V  +L    +       SM + W  P     ++ ++++ +    +    G  +   +   P+    +  Y+K    + ++SP   Y+++V  +         Y      +  T MA P+ +  P+   +VN   + + L   + +E  G I  YYL++   +   K+N  K      + + L   +KP    +P + A+F     ++    +F +G       +      T+  L R      +K Y++F+RA +            F+E  S    +  P  +       N+   P ++    K + ++    ++  ++    I   ++ V C +KRRR  +   +P +  +      +  + +   +GP    P+        DM    + NF+   +  HPPIP    A++I  LK+NDN KF++EYESI+PG  FTW  SNLE NK KNRYANV AYDHSRV L  +  + GSDYINANYCDGYRK NAY+ATQGPL ETF  FWRM WE + A IVMMT+LEER R+KCDQYWPTRG+E Y +  ++I   ET ELA Y++R F L ++      G  + R++   QFT WPDHGVPD   P L F++R R+  P +SGP++VHCSAGVGRTG YIV+DS L +++HEK++D+YG V+ LRAQRNYMVQTE+QY+FI+DA+LEA +CG TEV  R+LH H+ KL        +T   +  +GME+EFK LS +     +F TANLP N+ KNRL++ILPYE+ RV L PI   +GSDY+NASFIDGYR + AYIA QGP+ +   DFWRMLW+HNS+IVVML++L+EMGREKC QYWP ERS  +   +V+P+ EYNMP + LREF+V  +  +  +RT+RQFQF+DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGR+GVF+ LSIVL+RM+ EG +D+FQTVR+LR QRP MVQTEDQY FCY  ALEYL SFD +
Sbjct:   14 HVNP----PEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISILRIEPVRAGRDDAPY--ECVAENGVGDAVSADATLTIYEGDK-TPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL-----QYYVIQYKPKNANQAFSEISGI-------ITMYYVVRALSPYTEYEFYVIAVNN-IGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHKRISNSEA----------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKD-----QALKEEMLSGPQMTKK--------RFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRK-------AVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLLGYKIFYTMTAV-EDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAAR-FKNGLGRLSEKVTVRIKPEDVPLNLRAHDVS----THSMTLSWSPPIRLTPVN-YKISFDAMKVFVDSQGFSQ---TQIVPKREIILKHYVK-THTINELSPFTTYNVNVSAI----PSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILP--QASEEYGPISHYYLVV---VPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFP----QRSIPFTFHLGSGDDYHNF------TNRKLER------EKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREA-PPGERPHRPDPNWPAEPEVSVNRNKDEPEIL--WVVLPLMVSTFIVSTALIVLCVVKRRR--QPCKTPDQAAVT-----RPLMAADLGAGPTPSDPV--------DMR---RLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTIT--ETQELATYSIRTFQLCRQ------GFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLL-------ITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDA-RDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNY 2009          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Zebrafish
Match: ptprfb (protein tyrosine phosphatase receptor type Fb [Source:NCBI gene;Acc:799867])

HSP 1 Score: 853.588 bits (2204), Expect = 0.000e+0
Identity = 391/604 (64.74%), Postives = 474/604 (78.48%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            N++   + +HPPI    LAD+I  LK ND  +F++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRVVL+ ++ +PGSDYIN+NY DGYRKQNAYIATQGPLPET   FWRM+WE R + IVMMT+LEE+ RVKCDQYWP RG+E Y    + +  L+ VELA Y++R F+L K      NGS E R+V  FQF  WPDHGVP+   P+L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +++HEK VD+YG V+ +R+QRNYMVQTE+QY+FI++ALLEA+ CGNTEV  R+L+AH+ KL QP        + +  T MELEFK L+       +F +ANLP N+ KNRL+NI+P+E+ RVCLQPIR  +GSDYINAS IDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP++GE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VDLFQTV+ LR QRP MVQTEDQYQ CY  ALEYL SFD + +
Sbjct: 1319 NYQTPGMREHPPISVSELADHIERLKANDALRFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINSNYIDGYRKQNAYIATQGPLPETLSDFWRMIWEQRASTIVMMTRLEEKSRVKCDQYWPIRGTETYGM--IQVTMLDAVELATYSVRTFALYK------NGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLTQP-------SAGETVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1906          

HSP 2 Score: 277.33 bits (708), Expect = 2.302e-74
Identity = 275/1091 (25.21%), Postives = 475/1091 (43.54%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKY-----VIPIP--SGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLS-EPRRTMLRSG------SIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND--LTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWS-PPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPD-RTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRK--GMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVP-SPPLNIRLNQLRQKTESGLTLLLADIAWDPPINS--HGTIRAYRIRHNLV------GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQG-PWSSDVNFRTVVLLPDP-PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIES-CNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRVTIN 3408
             + +P+ QT + G  A F CQ  G P   ++ +  G K       VI     SG +LRI  ++    + +  +C   N   E   +A L V + ++ +P+GFP   +     V +  +   M C   G    +  WFKD  P+D++   R   LRSG      ++  +   + D G YEC A N  G+  S    L +R   + P++   P + EV PG  VNLTC A G P P ++W+T       D  +    ++L LT+I +  +Y C A +S+G+I+   QV VK +PK P ++T      T   ++W+  NPE   P   + +     + D     +  +              Y++  L PY+ Y  +V+A +  +G   PS+ +   T E  PSSPP  V A   + +++ V+W PP E NG+I  Y +YY+ +L  P++ WQK  T    +  I+ L T  TY ++V    S G GP S+   +  + GVP QP +F       T I L W  P Q P     L Y                + + +I +  D    Y +  L P+TLY  SLAAR+E G GV ++ +  RT    P++ P  + + +LS TSI + W          +I  + +      S + V+  +    ++  + A      D    ++  LE    Y++  W    + +        V+ R    VP +PP  + +  L              + W PP++   HG IR Y++ ++ +      G  N+++      +++   ++ V           L     Y  +VAA  T   G   K  V T   A    P  I I+    ++  I WQPP  ++  G L+ Y++ Y     +N  IR  S  + +  +  L +   Y+F + A  + G G  +  D+   T   +P   P+N++   +  +  ++TWE   LS  N  +++ + + Y      +DI S  N+ +    T +T+  ++ ++ Y + +++        +  +I +  +S  P       +S   +  ++ S+ + W+ P+ + +   F++  N
Sbjct:   37 FVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAI-YECTATNSLGEINTSAKLTVLEENQ-IPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGRIKQLRSGGSPIRGALQIENSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNPE---PVSYYIIQYRAKTSDTNFQEVDGVATTR----------YSIGGLSPYSEYEFRVMAVNN-IGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQDPIIKYELQYWE-------------ADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTV------SYQAVNGEDTERHEVPDIGA------DASSCVLEGLEKWTEYQV--WVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTA--------IRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMD------VALPEAQEAV--------IAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMI-ISTTVGNTALIQWQPP--KDMVGELMGYRLRYKRLEEENYEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIG--TPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNG-RIIHYIVVY------RDINSKQNSTNRTSDTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAF----ATSFGVKAVMKTSVLLTWEVPENYKSQVPFKILYN 1046          

HSP 3 Score: 166.777 bits (421), Expect = 1.364e-40
Identity = 242/1055 (22.94%), Postives = 436/1055 (41.33%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVR---------------IDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND---------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKIP-VNITCLNIGPTDAQISWEQNPESDLPAESFTLM-IADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV--------RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVR---PGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSP-IGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYE-KNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK-NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKG 3228
            +L V++E+  P  G   I + PQ + V    T    C   GNP   ++       K  +P+      RI  ++ + G P+R                +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W      L   E     +  G    +      S  Y C AI+ +G ++    ++ ++  P  P  +     V       V LT  + GNP P   ++ QY    +D          T + SI  L+  +E    +   NN   G     V+ R  ++ P  P +++    +  +   + WE   E +     + +   +DL   +  L   Q  N      D+  +T  ++ L     YS++V+ F+ ++GD  PS  + ++T++  P+ P  S  A A+  T I + W  P++    I  Y + Y          W+     + HV         +  L  +  Y   + A +  G G  + P         P  PPQ  +     ++STSI + W +PP       ++ Y + Y+ ++G+     T + E   I  D +   +  L   T Y + + A T+ G G  +T + +RT   VP +P   ++V  L+ T+I + W+  +  ++   I  +++   +L++ E   + N M V +           +  E +I  L +  +Y + + +  + G  A     +V T     VP  P  I        T  G T L   I W PP +  G +  YR+R+  +  +N              YE +  + T+      +L  G  Y F ++A N A +G E   ++ T E  P  +P+++ + G+T+ +  ++W+PP +   NG +++Y V Y     K N+T RT+ T      I+GL+ +  Y  +V+AFT  G GP S  +  RT+   P    +     + +  + +TWE+   N    V FKI Y  Q++  +++       G +    +  +Q ++DY   + S+G
Sbjct:  123 KLTVLEENQIPH-GFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWF-----KDFLPVDINGNGRIKQLR-SGGSPIRGALQIENSEESDQGKYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEVMPGGSVNLTC-VAVGAPMPYVKWMTGEVELTKDEE----MPVGRNVLELTNIRQSTNYTCVAISSLG-MIEATAQVSVKALPKPPTSL----TVTETTATSVTLTWDS-GNPEPVSYYIIQYRAKTSDTNFQEVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDL---DAPLSAWQKHNT-----DDSRLT-TISSLTTGITYSLRVLGFT-SVGDGPPSDVLQVKTQQGVPAQP-SSFEAEAELDTRILLTWLWPVQ--DPIIKYELQY----------WEADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQ--DVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGED----TERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVAL----------PEAQEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTT--GAVPGKPTMI------ISTTVGNTAL---IQWQPPKDMVGELMGYRLRYKRLEEEN--------------YEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNGRIIHYIVVYRDINSKQNSTNRTSDT---QMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAFATSFGVKAVMKTSVLLTWEVPE-NYKSQVPFKILYNQQSV--EVQ-------GNLKRKLITRLQPDTDYSFVLMSRG 1078          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Zebrafish
Match: ptprfb (protein tyrosine phosphatase receptor type Fb [Source:NCBI gene;Acc:799867])

HSP 1 Score: 853.588 bits (2204), Expect = 0.000e+0
Identity = 391/604 (64.74%), Postives = 474/604 (78.48%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            N++   + +HPPI    LAD+I  LK ND  +F++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRVVL+ ++ +PGSDYIN+NY DGYRKQNAYIATQGPLPET   FWRM+WE R + IVMMT+LEE+ RVKCDQYWP RG+E Y    + +  L+ VELA Y++R F+L K      NGS E R+V  FQF  WPDHGVP+   P+L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +++HEK VD+YG V+ +R+QRNYMVQTE+QY+FI++ALLEA+ CGNTEV  R+L+AH+ KL QP        + +  T MELEFK L+       +F +ANLP N+ KNRL+NI+P+E+ RVCLQPIR  +GSDYINAS IDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP++GE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VDLFQTV+ LR QRP MVQTEDQYQ CY  ALEYL SFD + +
Sbjct: 1326 NYQTPGMREHPPISVSELADHIERLKANDALRFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINSNYIDGYRKQNAYIATQGPLPETLSDFWRMIWEQRASTIVMMTRLEEKSRVKCDQYWPIRGTETYGM--IQVTMLDAVELATYSVRTFALYK------NGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLTQP-------SAGETVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1913          

HSP 2 Score: 288.5 bits (737), Expect = 9.636e-78
Identity = 278/1085 (25.62%), Postives = 475/1085 (43.78%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKY-----VIPIP--SGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLS-EPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND--LTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWS-PPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPD-RTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRK--GMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVP-SPPLNIRLNQLRQKTESGLTLLLADIAWDPPINS--HGTIRAYRIRHNLV------GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQG-PWSSDVNFRTVVLLPDP-PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIES-CNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRVTIN 3408
             + +P+ QT + G  A F CQ  G P   ++ +  G K       VI     SG +LRI  ++    + +  +C   N   E   +A L V + ++ +P+GFP   +     V +  +   M C   G    +  WFKD  P+D++   R   LRSG++  +   + D G YEC A N  G+  S    L +R   + P++   P + EV PG  VNLTC A G P P ++W+T       D  +    ++L LT+I +  +Y C A +S+G+I+   QV VK +PK P ++T      T   ++W+  NPE   P   + +     + D     +  +              Y++  L PY+ Y  +V+A +  +G   PS+ +   T E  PSSPP  V A   + +++ V+W PP E NG+I  Y +YY+ +L  P++ WQK  T    +  I+ L T  TY ++V    S G GP S+   +  + GVP QP +F       T I L W  P Q P     L Y                + + +I +  D    Y +  L P+TLY  SLAAR+E G GV ++ +  RT    P++ P  + + +LS TSI + W          +I  + +      S + V+  +    ++  + A      D    ++  LE    Y++  W    + +        V+ R    VP +PP  + +  L              + W PP++   HG IR Y++ ++ +      G  N+++ +       K+ E     T Y      L     Y  +VAA  T   G   K  V T   A    P  I I+    ++  I WQPP  ++  G L+ Y++ Y     +N  IR  S  + +  +  L +   Y+F + A  + G G  +  D+   T   +P   P+N++   +  +  ++TWE   LS  N  +++ + + Y      +DI S  N+ +    T +T+  ++ ++ Y + +++        +  +I +  +S  P       +S   +  ++ S+ + W+ P+ + +   F++  N
Sbjct:   37 FVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAI-YECTATNSLGEINTSAKLTVLEENQ-IPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGRIKQLRSGALQIENSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNPE---PVSYYIIQYRAKTSDTNFQEVDGVATTR----------YSIGGLSPYSEYEFRVMAVNN-IGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQDPIIKYELQYWE-------------ADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTV------SYQAVNGEDTERHEVPDIGA------DASSCVLEGLEKWTEYQV--WVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTA--------IRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMD-VALPEAQWKIEES----TEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMI-ISTTVGNTALIQWQPP--KDMVGELMGYRLRYKRLEEENYEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIG--TPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNG-RIIHYIVVY------RDINSKQNSTNRTSDTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAF----ATSFGVKAVMKTSVLLTWEVPENYKSQVPFKILYN 1049          

HSP 3 Score: 172.17 bits (435), Expect = 3.482e-42
Identity = 244/1047 (23.30%), Postives = 442/1047 (42.22%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLL-------YNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND---------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKIP-VNITCLNIGPTDAQISWEQNPESDLPAESFTLM-IADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV--------RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVR---PGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSP-IGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYE-KNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK-NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKG 3228
            +L V++E+  P  G   I + PQ + V    T    C   GNP   ++          NG  + +  + SG  L+I + + +D    + +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W      L   E     +  G    +      S  Y C AI+ +G ++    ++ ++  P  P  +     V       V LT  + GNP P   ++ QY    +D          T + SI  L+  +E    +   NN   G     V+ R  ++ P  P +++    +  +   + WE   E +     + +   +DL   +  L   Q  N      D+  +T  ++ L     YS++V+ F+ ++GD  PS  + ++T++  P+ P  S  A A+  T I + W  P++    I  Y + Y          W+     + HV         +  L  +  Y   + A +  G G  + P         P  PPQ  +     ++STSI + W +PP       ++ Y + Y+ ++G+     T + E   I  D +   +  L   T Y + + A T+ G G  +T + +RT   VP +P   ++V  L+ T+I + W+  +  ++   I  +++   +L++ E   + N M V +     K +  ++ YE +I  L +  +Y + + +  + G  A     +V T     VP  P  I        T  G T L   I W PP +  G +  YR+R+  +  +N              YE +  + T+      +L  G  Y F ++A N A +G E   ++ T E  P  +P+++ + G+T+ +  ++W+PP +   NG +++Y V Y     K N+T RT+ T      I+GL+ +  Y  +V+AFT  G GP S  +  RT+   P    +     + +  + +TWE+   N    V FKI Y  Q++  +++       G +    +  +Q ++DY   + S+G
Sbjct:  123 KLTVLEENQIPH-GFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGR-IKQLRSG-ALQIENSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEVMPGGSVNLTC-VAVGAPMPYVKWMTGEVELTKDEE----MPVGRNVLELTNIRQSTNYTCVAISSLG-MIEATAQVSVKALPKPPTSL----TVTETTATSVTLTWDS-GNPEPVSYYIIQYRAKTSDTNFQEVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDL---DAPLSAWQKHNT-----DDSRLT-TISSLTTGITYSLRVLGFT-SVGDGPPSDVLQVKTQQGVPAQP-SSFEAEAELDTRILLTWLWPVQ--DPIIKYELQY----------WEADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQ--DVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGED----TERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKIEESTE-YEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTT--GAVPGKPTMI------ISTTVGNTAL---IQWQPPKDMVGELMGYRLRYKRLEEEN--------------YEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNGRIIHYIVVYRDINSKQNSTNRTSDT---QMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAFATSFGVKAVMKTSVLLTWEVPE-NYKSQVPFKILYNQQSV--EVQ-------GNLKRKLITRLQPDTDYSFVLMSRG 1081          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Zebrafish
Match: ptprfb (protein tyrosine phosphatase receptor type Fb [Source:NCBI gene;Acc:799867])

HSP 1 Score: 853.588 bits (2204), Expect = 0.000e+0
Identity = 391/604 (64.74%), Postives = 474/604 (78.48%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            N++   + +HPPI    LAD+I  LK ND  +F++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRVVL+ ++ +PGSDYIN+NY DGYRKQNAYIATQGPLPET   FWRM+WE R + IVMMT+LEE+ RVKCDQYWP RG+E Y    + +  L+ VELA Y++R F+L K      NGS E R+V  FQF  WPDHGVP+   P+L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +++HEK VD+YG V+ +R+QRNYMVQTE+QY+FI++ALLEA+ CGNTEV  R+L+AH+ KL QP        + +  T MELEFK L+       +F +ANLP N+ KNRL+NI+P+E+ RVCLQPIR  +GSDYINAS IDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP++GE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VDLFQTV+ LR QRP MVQTEDQYQ CY  ALEYL SFD + +
Sbjct: 1328 NYQTPGMREHPPISVSELADHIERLKANDALRFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINSNYIDGYRKQNAYIATQGPLPETLSDFWRMIWEQRASTIVMMTRLEEKSRVKCDQYWPIRGTETYGM--IQVTMLDAVELATYSVRTFALYK------NGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLTQP-------SAGETVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1915          

HSP 2 Score: 281.952 bits (720), Expect = 9.492e-76
Identity = 279/1089 (25.62%), Postives = 474/1089 (43.53%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKY-----VIPIP--SGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLS-EPRRTMLRSG------SIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND--LTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWS-PPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPD-RTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVP-SPPLNIRLNQLRQKTESGLTLLLADIAWDPPINS--HGTIRAYRIRHNLV------GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQG-PWSSDVNFRTVVLLPDP-PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIES-CNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRVTIN 3408
             + +P+ QT + G  A F CQ  G P   ++ +  G K       VI     SG +LRI  ++    + +  +C   N   E   +A L V + ++ +P+GFP   +     V +  +   M C   G    +  WFKD  P+D++   R   LRSG      ++  +   + D G YEC A N  G+  S    L +R   + P++   P + EV PG  VNLTC A G P P ++W+T       D  +    ++L LT+I +  +Y C A +S+G+I+   QV VK +PK P ++T      T   ++W+  NPE   P   + +     + D     +  +              Y++  L PY+ Y  +V+A +  +G   PS+ +   T E  PSSPP  V A   + +++ V+W PP E NG+I  Y +YY+ +L  P++ WQK  T    +  I+ L T  TY ++V    S G GP S+   +  + GVP QP +F       T I L W  P Q P     L Y                + + +I +  D    Y +  L P+TLY  SLAAR+E G GV ++ +  RT    P++ P  + + +LS TSI + W        + S     V    S + V+  +    ++  + A      D    ++  LE    Y++  W    + +        V+ R    VP +PP  + +  L              + W PP++   HG IR Y++ ++ +      G  N+++ +       K+ E     T Y      L     Y  +VAA  T   G   K  V T   A    P  I I+    ++  I WQPP  ++  G L+ Y++ Y     +N  IR  S  + +  +  L +   Y+F + A  + G G  +  D+   T   +P   P+N++   +  +  ++TWE   LS  N  +++ + + Y      +DI S  N+ +    T +T+  ++ ++ Y + +++        +  +I +  +S  P       +S   +  ++ S+ + W+ P+ + +   F++  N
Sbjct:   37 FVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAI-YECTATNSLGEINTSAKLTVLEENQ-IPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGRIKQLRSGGSPIRGALQIENSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNPE---PVSYYIIQYRAKTSDTNFQEVDGVATTR----------YSIGGLSPYSEYEFRVMAVNN-IGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQDPIIKYELQYWE-------------ADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVA----PPAASRHGAIVRYTVSYQAVNGEDTERHEVPDIGA------DASSCVLEGLEKWTEYQV--WVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTA--------IRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMD-VALPEAQWKIEES----TEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMI-ISTTVGNTALIQWQPP--KDMVGELMGYRLRYKRLEEENYEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIG--TPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNG-RIIHYIVVY------RDINSKQNSTNRTSDTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAF----ATSFGVKAVMKTSVLLTWEVPENYKSQVPFKILYN 1055          

HSP 3 Score: 173.711 bits (439), Expect = 1.213e-42
Identity = 244/1055 (23.13%), Postives = 440/1055 (41.71%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVR---------------IDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND---------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKIP-VNITCLNIGPTDAQISWEQNPESDLPAESFTLM-IADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV--------RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVR---PGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSP-IGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYE-KNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK-NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKG 3228
            +L V++E+  P  G   I + PQ + V    T    C   GNP   ++       K  +P+      RI  ++ + G P+R                +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W      L   E     +  G    +      S  Y C AI+ +G ++    ++ ++  P  P  +     V       V LT  + GNP P   ++ QY    +D          T + SI  L+  +E    +   NN   G     V+ R  ++ P  P +++    +  +   + WE   E +     + +   +DL   +  L   Q  N      D+  +T  ++ L     YS++V+ F+ ++GD  PS  + ++T++  P+ P  S  A A+  T I + W  P++    I  Y + Y          W+     + HV         +  L  +  Y   + A +  G G  + P         P  PPQ  +     ++STSI + W +PP       ++ Y + Y+ ++G+     T + E   I  D +   +  L   T Y + + A T+ G G  +T + +RT   VP +P   ++V  L+ T+I + W+  +  ++   I  +++   +L++ E   + N M V +     K +  ++ YE +I  L +  +Y + + +  + G  A     +V T     VP  P  I        T  G T L   I W PP +  G +  YR+R+  +  +N              YE +  + T+      +L  G  Y F ++A N A +G E   ++ T E  P  +P+++ + G+T+ +  ++W+PP +   NG +++Y V Y     K N+T RT+ T      I+GL+ +  Y  +V+AFT  G GP S  +  RT+   P    +     + +  + +TWE+   N    V FKI Y  Q++  +++       G +    +  +Q ++DY   + S+G
Sbjct:  123 KLTVLEENQIPH-GFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWF-----KDFLPVDINGNGRIKQLR-SGGSPIRGALQIENSEESDQGKYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEVMPGGSVNLTC-VAVGAPMPYVKWMTGEVELTKDE----EMPVGRNVLELTNIRQSTNYTCVAISSLG-MIEATAQVSVKALPKPPTSL----TVTETTATSVTLTWDS-GNPEPVSYYIIQYRAKTSDTNFQEVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDL---DAPLSAWQKHNT-----DDSRLT-TISSLTTGITYSLRVLGFT-SVGDGPPSDVLQVKTQQGVPAQP-SSFEAEAELDTRILLTWLWPVQ--DPIIKYELQY----------WEADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQ--DVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGED----TERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKIEESTE-YEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTT--GAVPGKPTMI------ISTTVGNTAL---IQWQPPKDMVGELMGYRLRYKRLEEEN--------------YEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNGRIIHYIVVYRDINSKQNSTNRTSDT---QMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAFATSFGVKAVMKTSVLLTWEVPE-NYKSQVPFKILYNQQSV--EVQ-------GNLKRKLITRLQPDTDYSFVLMSRG 1087          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Zebrafish
Match: ptprfb (protein tyrosine phosphatase receptor type Fb [Source:NCBI gene;Acc:799867])

HSP 1 Score: 853.588 bits (2204), Expect = 0.000e+0
Identity = 391/604 (64.74%), Postives = 474/604 (78.48%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            N++   + +HPPI    LAD+I  LK ND  +F++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRVVL+ ++ +PGSDYIN+NY DGYRKQNAYIATQGPLPET   FWRM+WE R + IVMMT+LEE+ RVKCDQYWP RG+E Y    + +  L+ VELA Y++R F+L K      NGS E R+V  FQF  WPDHGVP+   P+L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +++HEK VD+YG V+ +R+QRNYMVQTE+QY+FI++ALLEA+ CGNTEV  R+L+AH+ KL QP        + +  T MELEFK L+       +F +ANLP N+ KNRL+NI+P+E+ RVCLQPIR  +GSDYINAS IDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP++GE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VDLFQTV+ LR QRP MVQTEDQYQ CY  ALEYL SFD + +
Sbjct: 1322 NYQTPGMREHPPISVSELADHIERLKANDALRFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINSNYIDGYRKQNAYIATQGPLPETLSDFWRMIWEQRASTIVMMTRLEEKSRVKCDQYWPIRGTETYGM--IQVTMLDAVELATYSVRTFALYK------NGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLTQP-------SAGETVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1909          

HSP 2 Score: 288.886 bits (738), Expect = 7.428e-78
Identity = 278/1085 (25.62%), Postives = 475/1085 (43.78%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKY-----VIPIP--SGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLS-EPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND--LTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWS-PPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPD-RTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRK--GMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVP-SPPLNIRLNQLRQKTESGLTLLLADIAWDPPINS--HGTIRAYRIRHNLV------GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQG-PWSSDVNFRTVVLLPDP-PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIES-CNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRVTIN 3408
             + +P+ QT + G  A F CQ  G P   ++ +  G K       VI     SG +LRI  ++    + +  +C   N   E   +A L V + ++ +P+GFP   +     V +  +   M C   G    +  WFKD  P+D++   R   LRSG++  +   + D G YEC A N  G+  S    L +R   + P++   P + EV PG  VNLTC A G P P ++W+T       D  +    ++L LT+I +  +Y C A +S+G+I+   QV VK +PK P ++T      T   ++W+  NPE   P   + +     + D     +  +              Y++  L PY+ Y  +V+A +  +G   PS+ +   T E  PSSPP  V A   + +++ V+W PP E NG+I  Y +YY+ +L  P++ WQK  T    +  I+ L T  TY ++V    S G GP S+   +  + GVP QP +F       T I L W  P Q P     L Y                + + +I +  D    Y +  L P+TLY  SLAAR+E G GV ++ +  RT    P++ P  + + +LS TSI + W          +I  + +      S + V+  +    ++  + A      D    ++  LE    Y++  W    + +        V+ R    VP +PP  + +  L              + W PP++   HG IR Y++ ++ +      G  N+++ +       K+ E     T Y      L     Y  +VAA  T   G   K  V T   A    P  I I+    ++  I WQPP  ++  G L+ Y++ Y     +N  IR  S  + +  +  L +   Y+F + A  + G G  +  D+   T   +P   P+N++   +  +  ++TWE   LS  N  +++ + + Y      +DI S  N+ +    T +T+  ++ ++ Y + +++        +  +I +  +S  P       +S   +  ++ S+ + W+ P+ + +   F++  N
Sbjct:   37 FVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAI-YECTATNSLGEINTSAKLTVLEENQ-IPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGRIKQLRSGALQIENSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNPE---PVSYYIIQYRAKTSDTNFQEVDGVATTR----------YSIGGLSPYSEYEFRVMAVNN-IGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQDPIIKYELQYWE-------------ADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTV------SYQAVNGEDTERHEVPDIGA------DASSCVLEGLEKWTEYQV--WVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTA--------IRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMD-VALPEAQWKIEES----TEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMI-ISTTVGNTALIQWQPP--KDMVGELMGYRLRYKRLEEENYEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIG--TPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNG-RIIHYIVVY------RDINSKQNSTNRTSDTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAF----ATSFGVKAVMKTSVLLTWEVPENYKSQVPFKILYN 1049          

HSP 3 Score: 172.555 bits (436), Expect = 2.987e-42
Identity = 244/1047 (23.30%), Postives = 439/1047 (41.93%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLL-------YNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND---------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKIP-VNITCLNIGPTDAQISWEQNPESDLPAESFTLM-IADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV--------RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVR---PGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSP-IGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYE-KNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK-NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKG 3228
            +L V++E+  P  G   I + PQ + V    T    C   GNP   ++          NG  + +  + SG  L+I + + +D    + +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W      L   E     +  G    +      S  Y C AI+ +G ++    ++ ++  P  P  +     V       V LT  + GNP P   ++ QY    +D          T + SI  L+  +E    +   NN   G     V+ R  ++ P  P +++    +  +   + WE   E +     + +   +DL   +  L   Q  N      D+  +T  ++ L     YS++V+ F+ ++GD  PS  + ++T++  P+ P  S  A A+  T I + W  P++    I  Y + Y          W+     + HV         +  L  +  Y   + A +  G G  + P         P  PPQ  +     ++STSI + W +PP       ++ Y + Y+ ++G+     T + E   I  D +   +  L   T Y + + A T+ G G  +T + +RT   VP +P   ++V  L+ T+I + W+  +  ++   I  +++   +L++ E   + N M V +     K +  ++ YE +I  L +  +Y + + +  + G  A     +V T     VP  P  I        T  G T L   I W PP +  G +  YR+R+  +  +N              YE +  + T+      +L  G  Y F ++A N A +G E   ++ T E  P  +P+++ + G+T+ +  ++W+PP +   NG +++Y V Y     K N+T RT+ T      I+GL+ +  Y  +V+AFT  G GP S  +  RT+   P    +     + +  + +TWE+   N    V FKI Y  Q++            G +    +  +Q ++DY   + S+G
Sbjct:  123 KLTVLEENQIPH-GFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGR-IKQLRSG-ALQIENSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEVMPGGSVNLTC-VAVGAPMPYVKWMTGEVELTKDEE----MPVGRNVLELTNIRQSTNYTCVAISSLG-MIEATAQVSVKALPKPPTSL----TVTETTATSVTLTWDS-GNPEPVSYYIIQYRAKTSDTNFQEVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDL---DAPLSAWQKHNT-----DDSRLT-TISSLTTGITYSLRVLGFT-SVGDGPPSDVLQVKTQQGVPAQP-SSFEAEAELDTRILLTWLWPVQ--DPIIKYELQY----------WEADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQ--DVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGED----TERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKIEESTE-YEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTT--GAVPGKPTMI------ISTTVGNTAL---IQWQPPKDMVGELMGYRLRYKRLEEEN--------------YEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNGRIIHYIVVYRDINSKQNSTNRTSDT---QMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAFATSFGVKAVMKTSVLLTWEVPE-NYKSQVPFKILYNQQSVEVQ---------GNLKRKLITRLQPDTDYSFVLMSRG 1081          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Zebrafish
Match: ptprfb (protein tyrosine phosphatase receptor type Fb [Source:NCBI gene;Acc:799867])

HSP 1 Score: 853.203 bits (2203), Expect = 0.000e+0
Identity = 391/604 (64.74%), Postives = 474/604 (78.48%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            N++   + +HPPI    LAD+I  LK ND  +F++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRVVL+ ++ +PGSDYIN+NY DGYRKQNAYIATQGPLPET   FWRM+WE R + IVMMT+LEE+ RVKCDQYWP RG+E Y    + +  L+ VELA Y++R F+L K      NGS E R+V  FQF  WPDHGVP+   P+L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +++HEK VD+YG V+ +R+QRNYMVQTE+QY+FI++ALLEA+ CGNTEV  R+L+AH+ KL QP        + +  T MELEFK L+       +F +ANLP N+ KNRL+NI+P+E+ RVCLQPIR  +GSDYINAS IDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP++GE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VDLFQTV+ LR QRP MVQTEDQYQ CY  ALEYL SFD + +
Sbjct: 1211 NYQTPGMREHPPISVSELADHIERLKANDALRFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINSNYIDGYRKQNAYIATQGPLPETLSDFWRMIWEQRASTIVMMTRLEEKSRVKCDQYWPIRGTETYGM--IQVTMLDAVELATYSVRTFALYK------NGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLTQP-------SAGETVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1798          

HSP 2 Score: 343.969 bits (881), Expect = 5.509e-95
Identity = 281/1011 (27.79%), Postives = 463/1011 (45.80%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKY-----VIPIP--SGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLS-EPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND--LTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWS-PPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPD-RTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNSP-IGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYE-KNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK-NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKG 3228
             + +P+ QT + G  A F CQ  G P   ++ +  G K       VI     SG +LRI  ++    + +  +C   N   E   +A L V + ++ +P+GFP   +     V +  +   M C   G    +  WFKD  P+D++   R   LRSG++  +   + D G YEC A N  G+  S    L +R   + P++   P + EV PG  VNLTC A G P P ++W+T       D  +    ++L LT+I +  +Y C A +S+G+I+   QV VK +PK P ++T      T   ++W+  NPE   P   + +     + D     +  +              Y++  L PY+ Y  +V+A +  +G   PS+ +   T E  PSSPP  V A   + +++ V+W PP E NG+I  Y +YY+ +L  P++ WQK  T    +  I+ L T  TY ++V    S G GP S+   +  + GVP QP +F       T I L W  P Q P     L Y                + + +I +  D    Y +  L P+TLY  SLAAR+E G GV ++ +  RT   VP +P   ++V  L+ T+I + W+  +  ++   I  +++   +L++ E   + N M V +           +  E +I  L +  +Y + + +  + G  A     +V T     VP  P  I        T  G T L   I W PP +  G +  YR+R+  +  +N              YE +  + T+      +L  G  Y F ++A N A +G E   ++ T E  P  +P+++ + G+T+ +  ++W+PP +   NG +++Y V Y     K N+T RT+ T      I+GL+ +  Y  +V+AFT  G GP S  +  RT+   P    +     + +  + +TWE+   N    V FKI Y  Q++  +++       G +    +  +Q ++DY   + S+G
Sbjct:   37 FVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAI-YECTATNSLGEINTSAKLTVLEENQ-IPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGRIKQLRSGALQIENSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNPE---PVSYYIIQYRAKTSDTNFQEVDGVATTR----------YSIGGLSPYSEYEFRVMAVNN-IGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQDPIIKYELQYWE-------------ADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVAL----------PEAQEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTT--GAVPGKPTMI------ISTTVGNTAL---IQWQPPKDMVGELMGYRLRYKRLEEEN--------------YEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNGRIIHYIVVYRDINSKQNSTNRTSDT---QMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAFATSFGVKAVMKTSVLLTWEVPE-NYKSQVPFKILYNQQSV--EVQ-------GNLKRKLITRLQPDTDYSFVLMSRG 970          

HSP 3 Score: 89.7373 bits (221), Expect = 3.597e-17
Identity = 218/995 (21.91%), Postives = 380/995 (38.19%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLL-------YNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND---------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKI-PVNITCLNIGPTDAQISWEQNPESDLPAESFTL-MIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV--------RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVR---PGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHI--PTLTNKEEEIK------ILPDRTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIG-LEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNG-----ILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVV-LLPDPPINIEASRINENQIKV 3045
            +L V++E+  P  G   I + PQ + V    T    C   GNP   ++          NG  + +  + SG  L+I + + +D    + +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W      L   E     +  G    +      S  Y C AI+ +G ++    ++ ++  P  P  +     V       V LT  + GNP P   ++ QY    +D          T + SI  L+  +E    +   NN   G     V+ R  ++ P   P+++    +  +   + WE   E +     + +   +DL   +  L   Q  N      D+  +T  ++ L     YS++V+ F+ ++GD  PS  + ++T++  P+  P S  A A+  T I + W  P++    I  Y + Y          W+     + HV         +  L  +  Y   + A +  G G  + P         PG PP+        + ST+I + W PP             ++  I G  +    L N E           LP+  +  +  L   T Y +++AA T  G G  S    V T   VP  P  I   T+  T++ I+W+   D    +  ++++  +L+         E + +I+   ++T +      + + DL  G  Y   L +   +GL   ++ DI    P ++    PLN+++         GLT     + W+PP  S    R  RI H +V           R ++ K    N T     T  G L     Y+  V A  +   G +   +   T  ++P ++  S  +  +   SV ++W+ P  EN+       IL N Q       LK              LI  LQ +  Y+F + +      G     V+ RT   L    P+   A + N  ++ +
Sbjct:  123 KLTVLEENQIPH-GFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGR-IKQLRSG-ALQIENSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEVMPGGSVNLTC-VAVGAPMPYVKWMTGEVELTKDEE----MPVGRNVLELTNIRQSTNYTCVAISSLG-MIEATAQVSVKALPKPPTSL----TVTETTATSVTLTWDS-GNPEPVSYYIIQYRAKTSDTNFQEVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDL---DAPLSAWQKHNT-----DDSRLT-TISSLTTGITYSLRVLGFT-SVGDGPPSDVLQVKTQQGVPAQ-PSSFEAEAELDTRILLTWLWPVQ--DPIIKYELQY----------WEADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSVPGAPPR--KLEVEALNSTAIRVTWKPP---------LSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTVGNTAL-IQWQPPKDMVGELMGYRLRYKRLE---------EENYEIREF-SRTDDH-----HTVTDLHKGATYSFHLSARNRAGLGEEYVKDI--GTPEDVPSGFPLNLQV--------VGLTTSTTRLTWEPPALSE---RNGRIIHYIV---------VYRDINSKQNSTNRTSDTQMTIQG-LRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSP-AFATSFGVKAVMKTSVLLTWEVP--ENYKSQVPFKILYNQQSVEVQGNLKR------------KLITRLQPDTDYSFVLMSRGNSAGG-LQQQVSIRTAPDLFKTKPVLYTADQTNNGKLTI 1008          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Xenopus
Match: sema6d (semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070])

HSP 1 Score: 872.078 bits (2252), Expect = 0.000e+0
Identity = 404/604 (66.89%), Postives = 478/604 (79.14%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDYIN+NY DGYRKQNAYIATQGPLPETF  FWRM+WE R A IVMMTKLEER R+KCDQYWP+RG+E Y    + I  L+TVELA YT+R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP +VQTEDQYQFCY   LEYL SFD + +
Sbjct: 1311 NFQTPGMANHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINSNYIDGYRKQNAYIATQGPLPETFGDFWRMMWEQRTATIVMMTKLEERSRIKCDQYWPSRGTETYGL--IQITLLDTVELATYTVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIRHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAVVQTEDQYQFCYRAGLEYLGSFDHYAT 1898          

HSP 2 Score: 285.034 bits (728), Expect = 1.540e-76
Identity = 278/1031 (26.96%), Postives = 452/1031 (43.84%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSG------SIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRHNLV--GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPI----NIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPV----TMVTLGNVQYNSDYQVGIKS 3222
            +I   P  Q  + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   T  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRSG      ++  ++  + D G YEC A N  G+  S    L +R   I P++   P + E+ PG  VN+TC A G+P P ++W+  ++   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +     S +      K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++  T E  PSSPP++V A   + T+I V+W  P E NG+I  Y VYY+ +    IN W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +      Y        G H       EE++  +   T YR+  L PN+LY+  LAAR + G+G S   ++ RT    P++ P  I   + S TSI + W      +++  I  + IK         VD  +    +I S+ ++T+      +Y++  LE    Y+I++ +   VG    S+P +      R    VPS PP  + +  +   +          ++W  P+    HG IR Y++ +  +  G       LK   L+   +E + T T +      L     Y  +V A  T   G   K  + +  +A    P  + I+    ++  I W PP VE   G ++ Y++ +    L   T    S    +     + +  LY F++ A  KVG G    +   + + +  +PP     NI     +   + +TW+  H N  +  G    Y L  + +DI   +     P+    T VTL  ++ ++ Y V +++
Sbjct:   18 RISETPVDQIGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNSVGEVATTTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDYLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRIAPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGVIEAIAQINVKALPKPPGTPMVTESTATSITLTWDSGNPE---PVSYYIIQHKPKSSEEQ---YKEIDGV-------ATTRYSVAGLSPYSEYEFRVVAVNN-IGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHINSWTKHNVADSQITTIGNLEPQKTYSVKVLAFTSVGDGPLSNDIQVITQTGVPSQPLNFKAEPESETSILLSWTPPRSDTISSYDLYYK-----EGDH------AEEQVITIDPATSYRLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQDIRCNSQSSTSILVSWLPPPVEKQNGKIMGYSIKYTG------VDTDDAKSHEILSISSETR------QYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILI-----RTDEDVPSGPPRKVEVEAVNSTS--------VKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEYDDT-TEHEMIISGLQPETAYSITVTAYTTKGDGARSKPKIVSTSAAVPGKPRLV-ISHTQMNTALIQWYPP-VETF-GPVIGYRLKFGRKDLDTLTTLEFSEKEEHFTATDIHKGALYIFKLSARNKVGYG----EEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQ--HPNLEERNGLLTKYTL--MYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRA 982          

HSP 3 Score: 170.244 bits (430), Expect = 1.920e-41
Identity = 263/1090 (24.13%), Postives = 454/1090 (41.65%), Query Frame = 1
Query:  157 IIQIILSNQI-VFAQWFRLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVR---------------IDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCT-AKGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKI-PVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDN---KNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRT-DYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSV---GSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTP-NLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            I + + SN +   A   RL V++E   PR G   I + PQ + V    TA   C   GNP   ++      K Y+    S    RI  ++ + G P+R                +C+  N SA  + +A  N+    + +    PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I  ++ ++  P        P    V      ++T T   GNP P   ++ Q H+P +            T + S+  L+  +E    +   NN   G     V  R  ++ P   P N+    +  T   + WE+  E +   + + +     ++D T        +I+ W   N     IT  + +L P   YSVKV+AF+ ++GD   S  I + T+   PS  P +  A  ++ TSI + W PP   +  I+ Y++YY     H   Q    +    + R+  L  N+ Y+ ++ A    G G  +       +  +P  PPQ  + R    +STSI + W PP  P +      +      +G  + T   K  EI  +   T  Y + +L   T Y I + A T+ G G  S+ + +RT+  VP+  P  ++V  ++ TS+ + WR  + N++   I  +++  +++++ E         V +     +  + ++ +E II+ L+    Y I + +    G    S P I       PG     P L I   Q+            A I W PP+ + G +  YR++    G ++L ++L     S K  E++ T T+       +  G +Y F ++A N    G E+   +S  E  P  +P +I     +S SV I+WQ P +E  NG+L  Y + Y    L +  I     P +    + GL+ +  Y  ++RA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y    +  +++       G  T   + N++  + Y   + ++G  N  G + +  TAK +
Sbjct:   88 IYECVASNSVGEVATTTRLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWF----KDYLPVDTSNNNGRIKQLR-SGGTPIRGALQIEQSEESDQGKYECVATN-SAGTRYSAPANLYVRVRRIA---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDV-------RQSANYTCVAMSTLGVIEAI-AQINVKALP------KPPGTPMVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKSSEEQYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVY---YTMDPT-------QHINSWTKHNVADSQIT-TIGNLEPQKTYSVKVLAFT-SVGDGPLSNDIQVITQTGVPSQ-PLNFKAEPESETSILLSWTPP--RSDTISSYDLYYKEG-DHAEEQVITIDPATSY-RLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQ--DIRCNSQSSTSILVSWLPP--PVEKQNGKIMGYSIKYTG--VDTDDAKSHEILSISSETRQYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILIRTDEDVPSGPPRKVEVEAVNSTSVKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEYDDTTE-HEMIISGLQPETAYSITVTAYTTKGDGARSKPKIVSTSAAVPGK----PRLVISHTQMN----------TALIQWYPPVETFGPVIGYRLK---FGRKDL-DTLTTLEFSEK--EEHFTATD-------IHKGALYIFKLSARNKVGYGEEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQHPNLEERNGLLTKYTLMYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRAHTSKGPGPFSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SALPFKILYDDGKMAMEVD-------GRATQKLITNLKPETSYSFVLTNRG--NSAGGLQHRVTAKTA 1090          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Xenopus
Match: sema6d (semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070])

HSP 1 Score: 872.078 bits (2252), Expect = 0.000e+0
Identity = 404/604 (66.89%), Postives = 478/604 (79.14%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDYIN+NY DGYRKQNAYIATQGPLPETF  FWRM+WE R A IVMMTKLEER R+KCDQYWP+RG+E Y    + I  L+TVELA YT+R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP +VQTEDQYQFCY   LEYL SFD + +
Sbjct: 1317 NFQTPGMANHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINSNYIDGYRKQNAYIATQGPLPETFGDFWRMMWEQRTATIVMMTKLEERSRIKCDQYWPSRGTETYGL--IQITLLDTVELATYTVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIRHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAVVQTEDQYQFCYRAGLEYLGSFDHYAT 1904          

HSP 2 Score: 285.804 bits (730), Expect = 9.546e-77
Identity = 278/1031 (26.96%), Postives = 452/1031 (43.84%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSG------SIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRHNLV--GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPI----NIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPV----TMVTLGNVQYNSDYQVGIKS 3222
            K+   P  Q  + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   T  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRSG      ++  ++  + D G YEC A N  G+  S    L +R   I P++   P + E+ PG  VN+TC A G+P P ++W+  ++   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +     S +      K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++  T E  PSSPP++V A   + T+I V+W  P E NG+I  Y VYY+ +    IN W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +      Y        G H       EE++  +   T YR+  L PN+LY+  LAAR + G+G S   ++ RT    P++ P  I   + S TSI + W      +++  I  + IK         VD  +    +I S+ ++T+      +Y++  LE    Y+I++ +   VG    S+P +      R    VPS PP  + +  +   +          ++W  P+    HG IR Y++ +  +  G       LK   L+   +E + T T +      L     Y  +V A  T   G   K  + +  +A    P  + I+    ++  I W PP VE   G ++ Y++ +    L   T    S    +     + +  LY F++ A  KVG G    +   + + +  +PP     NI     +   + +TW+  H N  +  G    Y L  + +DI   +     P+    T VTL  ++ ++ Y V +++
Sbjct:   24 KLTRTPVDQIGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNSVGEVATTTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDYLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRIAPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGVIEAIAQINVKALPKPPGTPMVTESTATSITLTWDSGNPE---PVSYYIIQHKPKSSEEQ---YKEIDGV-------ATTRYSVAGLSPYSEYEFRVVAVNN-IGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHINSWTKHNVADSQITTIGNLEPQKTYSVKVLAFTSVGDGPLSNDIQVITQTGVPSQPLNFKAEPESETSILLSWTPPRSDTISSYDLYYK-----EGDH------AEEQVITIDPATSYRLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQDIRCNSQSSTSILVSWLPPPVEKQNGKIMGYSIKYTG------VDTDDAKSHEILSISSETR------QYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILI-----RTDEDVPSGPPRKVEVEAVNSTS--------VKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEYDDT-TEHEMIISGLQPETAYSITVTAYTTKGDGARSKPKIVSTSAAVPGKPRLV-ISHTQMNTALIQWYPP-VETF-GPVIGYRLKFGRKDLDTLTTLEFSEKEEHFTATDIHKGALYIFKLSARNKVGYG----EEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQ--HPNLEERNGLLTKYTL--MYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRA 988          

HSP 3 Score: 170.244 bits (430), Expect = 1.924e-41
Identity = 263/1090 (24.13%), Postives = 454/1090 (41.65%), Query Frame = 1
Query:  157 IIQIILSNQI-VFAQWFRLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVR---------------IDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCT-AKGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKI-PVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDN---KNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRT-DYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSV---GSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTP-NLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            I + + SN +   A   RL V++E   PR G   I + PQ + V    TA   C   GNP   ++      K Y+    S    RI  ++ + G P+R                +C+  N SA  + +A  N+    + +    PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I  ++ ++  P        P    V      ++T T   GNP P   ++ Q H+P +            T + S+  L+  +E    +   NN   G     V  R  ++ P   P N+    +  T   + WE+  E +   + + +     ++D T        +I+ W   N     IT  + +L P   YSVKV+AF+ ++GD   S  I + T+   PS  P +  A  ++ TSI + W PP   +  I+ Y++YY     H   Q    +    + R+  L  N+ Y+ ++ A    G G  +       +  +P  PPQ  + R    +STSI + W PP  P +      +      +G  + T   K  EI  +   T  Y + +L   T Y I + A T+ G G  S+ + +RT+  VP+  P  ++V  ++ TS+ + WR  + N++   I  +++  +++++ E         V +     +  + ++ +E II+ L+    Y I + +    G    S P I       PG     P L I   Q+            A I W PP+ + G +  YR++    G ++L ++L     S K  E++ T T+       +  G +Y F ++A N    G E+   +S  E  P  +P +I     +S SV I+WQ P +E  NG+L  Y + Y    L +  I     P +    + GL+ +  Y  ++RA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y    +  +++       G  T   + N++  + Y   + ++G  N  G + +  TAK +
Sbjct:   94 IYECVASNSVGEVATTTRLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWF----KDYLPVDTSNNNGRIKQLR-SGGTPIRGALQIEQSEESDQGKYECVATN-SAGTRYSAPANLYVRVRRIA---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDV-------RQSANYTCVAMSTLGVIEAI-AQINVKALP------KPPGTPMVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKSSEEQYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVY---YTMDPT-------QHINSWTKHNVADSQIT-TIGNLEPQKTYSVKVLAFT-SVGDGPLSNDIQVITQTGVPSQ-PLNFKAEPESETSILLSWTPP--RSDTISSYDLYYKEG-DHAEEQVITIDPATSY-RLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQ--DIRCNSQSSTSILVSWLPP--PVEKQNGKIMGYSIKYTG--VDTDDAKSHEILSISSETRQYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILIRTDEDVPSGPPRKVEVEAVNSTSVKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEYDDTTE-HEMIISGLQPETAYSITVTAYTTKGDGARSKPKIVSTSAAVPGK----PRLVISHTQMN----------TALIQWYPPVETFGPVIGYRLK---FGRKDL-DTLTTLEFSEK--EEHFTATD-------IHKGALYIFKLSARNKVGYGEEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQHPNLEERNGLLTKYTLMYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRAHTSKGPGPFSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SALPFKILYDDGKMAMEVD-------GRATQKLITNLKPETSYSFVLTNRG--NSAGGLQHRVTAKTA 1096          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Xenopus
Match: sema6d (semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070])

HSP 1 Score: 870.537 bits (2248), Expect = 0.000e+0
Identity = 404/609 (66.34%), Postives = 479/609 (78.65%), Query Frame = 1
Query: 4396 SSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            S    N  ++ +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDYIN+NY DGYRKQNAYIATQGPLPETF  FWRM+WE R A IVMMTKLEER R+KCDQYWP+RG+E Y    + I  L+TVELA YT+R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP +VQTEDQYQFCY   LEYL SFD + +
Sbjct: 1324 SGYPRNLHSSSMANHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINSNYIDGYRKQNAYIATQGPLPETFGDFWRMMWEQRTATIVMMTKLEERSRIKCDQYWPSRGTETYGL--IQITLLDTVELATYTVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIRHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAVVQTEDQYQFCYRAGLEYLGSFDHYAT 1916          

HSP 2 Score: 289.656 bits (740), Expect = 6.349e-78
Identity = 273/1024 (26.66%), Postives = 450/1024 (43.95%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRH-NLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPI----NIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPV----TMVTLGNVQYNSDYQVGIKS 3222
            K+   P  Q  + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   T  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRSG++  ++  + D G YEC A N  G+  S    L +R   I P++   P + E+ PG  VN+TC A G+P P ++W+  ++   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +     S +      K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++  T E  PSSPP++V A   + T+I V+W  P E NG+I  Y VYY+ +    IN W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +      Y        G H       EE++  +   T YR+  L PN+LY+  LAAR + G+G S   ++ RT    P++ P  I   + S TSI + W      +++  I  + IK         VD  +    +I S+ ++T+      +Y++  LE    Y+I++ +   VG    S+P +      R    VPS PP  + +  +   +          ++W  P+    HG IR Y++ +  +   +   + + +  +     E  ++G    T          Y  +V A  T   G   K  + +  +A    P  + I+    ++  I W PP VE   G ++ Y++ +    L   T    S    +     + +  LY F++ A  KVG G    +   + + +  +PP     NI     +   + +TW+  H N  +  G    Y L  + +DI   +     P+    T VTL  ++ ++ Y V +++
Sbjct:   32 KLTRTPVDQIGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNSVGEVATTTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDYLPVDTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRIAPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGVIEAIAQINVKALPKPPGTPMVTESTATSITLTWDSGNPE---PVSYYIIQHKPKSSEEQ---YKEIDGV-------ATTRYSVAGLSPYSEYEFRVVAVNN-IGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHINSWTKHNVADSQITTIGNLEPQKTYSVKVLAFTSVGDGPLSNDIQVITQTGVPSQPLNFKAEPESETSILLSWTPPRSDTISSYDLYYK-----EGDH------AEEQVITIDPATSYRLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQDIRCNSQSSTSILVSWLPPPVEKQNGKIMGYSIKYTG------VDTDDAKSHEILSISSETR------QYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILI-----RTDEDVPSGPPRKVEVEAVNSTS--------VKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQEMIISGLQPET---------AYSITVTAYTTKGDGARSKPKIVSTSAAVPGKPRLV-ISHTQMNTALIQWYPP-VETF-GPVIGYRLKFGRKDLDTLTTLEFSEKEEHFTATDIHKGALYIFKLSARNKVGYG----EEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQ--HPNLEERNGLLTKYTL--MYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRA 981          

HSP 3 Score: 167.548 bits (423), Expect = 1.369e-40
Identity = 261/1082 (24.12%), Postives = 451/1082 (41.68%), Query Frame = 1
Query:  157 IIQIILSNQI-VFAQWFRLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM-------KKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCT-AKGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKI-PVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDN---KNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRT-DYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSV---GSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTP-NLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            I + + SN +   A   RL V++E   PR G   I + PQ + V    TA   C   GNP   ++   + +          +  + SG  L+I   + +D    + +C+  N SA  + +A  N+    + +    PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I  ++ ++  P        P    V      ++T T   GNP P   ++ Q H+P +            T + S+  L+  +E    +   NN   G     V  R  ++ P   P N+    +  T   + WE+  E +   + + +     ++D T        +I+ W   N     IT  + +L P   YSVKV+AF+ ++GD   S  I + T+   PS  P +  A  ++ TSI + W PP   +  I+ Y++YY     H   Q    +    + R+  L  N+ Y+ ++ A    G G  +       +  +P  PPQ  + R    +STSI + W PP  P +      +      +G  + T   K  EI  +   T  Y + +L   T Y I + A T+ G G  S+ + +RT+  VP+  P  ++V  ++ TS+ + WR  + N++   I  +++  +++++ E         V +          +D  E II+ L+    Y I + +    G    S P I       PG     P L I   Q+            A I W PP+ + G +  YR++    G ++L ++L     S K  E++ T T+       +  G +Y F ++A N    G E+   +S  E  P  +P +I     +S SV I+WQ P +E  NG+L  Y + Y    L +  I     P +    + GL+ +  Y  ++RA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y    +  +++       G  T   + N++  + Y   + ++G  N  G + +  TAK +
Sbjct:  102 IYECVASNSVGEVATTTRLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDYLPVDTSNNNGRIKQLRSG-ALQIEQSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRIA---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDV-------RQSANYTCVAMSTLGVIEAI-AQINVKALP------KPPGTPMVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKSSEEQYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVY---YTMDPT-------QHINSWTKHNVADSQIT-TIGNLEPQKTYSVKVLAFT-SVGDGPLSNDIQVITQTGVPSQ-PLNFKAEPESETSILLSWTPP--RSDTISSYDLYYKEG-DHAEEQVITIDPATSY-RLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQ--DIRCNSQSSTSILVSWLPP--PVEKQNGKIMGYSIKYTG--VDTDDAKSHEILSISSETRQYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILIRTDEDVPSGPPRKVEVEAVNSTSVKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVML----------ADAQEMIISGLQPETAYSITVTAYTTKGDGARSKPKIVSTSAAVPGK----PRLVISHTQMN----------TALIQWYPPVETFGPVIGYRLK---FGRKDL-DTLTTLEFSEK--EEHFTATD-------IHKGALYIFKLSARNKVGYGEEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQHPNLEERNGLLTKYTLMYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRAHTSKGPGPFSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SALPFKILYDDGKMAMEVD-------GRATQKLITNLKPETSYSFVLTNRG--NSAGGLQHRVTAKTA 1089          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Xenopus
Match: sema6d (semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070])

HSP 1 Score: 870.537 bits (2248), Expect = 0.000e+0
Identity = 404/609 (66.34%), Postives = 479/609 (78.65%), Query Frame = 1
Query: 4396 SSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            S    N  ++ +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDYIN+NY DGYRKQNAYIATQGPLPETF  FWRM+WE R A IVMMTKLEER R+KCDQYWP+RG+E Y    + I  L+TVELA YT+R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP +VQTEDQYQFCY   LEYL SFD + +
Sbjct: 1333 SGYPRNLHSSSMANHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINSNYIDGYRKQNAYIATQGPLPETFGDFWRMMWEQRTATIVMMTKLEERSRIKCDQYWPSRGTETYGL--IQITLLDTVELATYTVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIRHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAVVQTEDQYQFCYRAGLEYLGSFDHYAT 1925          

HSP 2 Score: 291.967 bits (746), Expect = 1.386e-78
Identity = 278/1025 (27.12%), Postives = 452/1025 (44.10%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRHNLV--GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPI----NIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPV----TMVTLGNVQYNSDYQVGIKS 3222
            K+   P  Q  + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   T  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRSG++  ++  + D G YEC A N  G+  S    L +R   I P++   P + E+ PG  VN+TC A G+P P ++W+  ++   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +     S +      K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++  T E  PSSPP++V A   + T+I V+W  P E NG+I  Y VYY+ +    IN W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +      Y        G H       EE++  +   T YR+  L PN+LY+  LAAR + G+G S   ++ RT    P++ P  I   + S TSI + W      +++  I  + IK         VD  +    +I S+ ++T+      +Y++  LE    Y+I++ +   VG    S+P +      R    VPS PP  + +  +   +          ++W  P+    HG IR Y++ +  +  G       LK   L+   +E + T T +      L     Y  +V A  T   G   K  + +  +A    P  + I+    ++  I W PP VE   G ++ Y++ +    L   T    S    +     + +  LY F++ A  KVG G    +   + + +  +PP     NI     +   + +TW+  H N  +  G    Y L  + +DI   +     P+    T VTL  ++ ++ Y V +++
Sbjct:   32 KLTRTPVDQIGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNSVGEVATTTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDYLPVDTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRIAPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGVIEAIAQINVKALPKPPGTPMVTESTATSITLTWDSGNPE---PVSYYIIQHKPKSSEEQ---YKEIDGV-------ATTRYSVAGLSPYSEYEFRVVAVNN-IGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHINSWTKHNVADSQITTIGNLEPQKTYSVKVLAFTSVGDGPLSNDIQVITQTGVPSQPLNFKAEPESETSILLSWTPPRSDTISSYDLYYK-----EGDH------AEEQVITIDPATSYRLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQDIRCNSQSSTSILVSWLPPPVEKQNGKIMGYSIKYTG------VDTDDAKSHEILSISSETR------QYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILI-----RTDEDVPSGPPRKVEVEAVNSTS--------VKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEYDDT-TEHEMIISGLQPETAYSITVTAYTTKGDGARSKPKIVSTSAAVPGKPRLV-ISHTQMNTALIQWYPP-VETF-GPVIGYRLKFGRKDLDTLTTLEFSEKEEHFTATDIHKGALYIFKLSARNKVGYG----EEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQ--HPNLEERNGLLTKYTL--MYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRA 990          

HSP 3 Score: 167.933 bits (424), Expect = 1.031e-40
Identity = 260/1082 (24.03%), Postives = 454/1082 (41.96%), Query Frame = 1
Query:  157 IIQIILSNQI-VFAQWFRLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM-------KKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCT-AKGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKI-PVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDN---KNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRT-DYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSV---GSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTP-NLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            I + + SN +   A   RL V++E   PR G   I + PQ + V    TA   C   GNP   ++   + +          +  + SG  L+I   + +D    + +C+  N SA  + +A  N+    + +    PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I  ++ ++  P        P    V      ++T T   GNP P   ++ Q H+P +            T + S+  L+  +E    +   NN   G     V  R  ++ P   P N+    +  T   + WE+  E +   + + +     ++D T        +I+ W   N     IT  + +L P   YSVKV+AF+ ++GD   S  I + T+   PS  P +  A  ++ TSI + W PP   +  I+ Y++YY     H   Q    +    + R+  L  N+ Y+ ++ A    G G  +       +  +P  PPQ  + R    +STSI + W PP  P +      +      +G  + T   K  EI  +   T  Y + +L   T Y I + A T+ G G  S+ + +RT+  VP+  P  ++V  ++ TS+ + WR  + N++   I  +++  +++++ E         V +     +  + ++ +E II+ L+    Y I + +    G    S P I       PG     P L I   Q+            A I W PP+ + G +  YR++    G ++L ++L     S K  E++ T T+       +  G +Y F ++A N    G E+   +S  E  P  +P +I     +S SV I+WQ P +E  NG+L  Y + Y    L +  I     P +    + GL+ +  Y  ++RA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y    +  +++       G  T   + N++  + Y   + ++G  N  G + +  TAK +
Sbjct:  102 IYECVASNSVGEVATTTRLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDYLPVDTSNNNGRIKQLRSG-ALQIEQSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRIA---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDV-------RQSANYTCVAMSTLGVIEAI-AQINVKALP------KPPGTPMVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKSSEEQYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVY---YTMDPT-------QHINSWTKHNVADSQIT-TIGNLEPQKTYSVKVLAFT-SVGDGPLSNDIQVITQTGVPSQ-PLNFKAEPESETSILLSWTPP--RSDTISSYDLYYKEG-DHAEEQVITIDPATSY-RLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQ--DIRCNSQSSTSILVSWLPP--PVEKQNGKIMGYSIKYTG--VDTDDAKSHEILSISSETRQYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILIRTDEDVPSGPPRKVEVEAVNSTSVKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEYDDTTE-HEMIISGLQPETAYSITVTAYTTKGDGARSKPKIVSTSAAVPGK----PRLVISHTQMN----------TALIQWYPPVETFGPVIGYRLK---FGRKDL-DTLTTLEFSEK--EEHFTATD-------IHKGALYIFKLSARNKVGYGEEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQHPNLEERNGLLTKYTLMYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRAHTSKGPGPFSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SALPFKILYDDGKMAMEVD-------GRATQKLITNLKPETSYSFVLTNRG--NSAGGLQHRVTAKTA 1098          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Xenopus
Match: sema6d (semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070])

HSP 1 Score: 869.766 bits (2246), Expect = 0.000e+0
Identity = 404/609 (66.34%), Postives = 479/609 (78.65%), Query Frame = 1
Query: 4396 SSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            S    N  ++ +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDYIN+NY DGYRKQNAYIATQGPLPETF  FWRM+WE R A IVMMTKLEER R+KCDQYWP+RG+E Y    + I  L+TVELA YT+R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP +VQTEDQYQFCY   LEYL SFD + +
Sbjct: 1310 SGYPRNLHSSSMANHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINSNYIDGYRKQNAYIATQGPLPETFGDFWRMMWEQRTATIVMMTKLEERSRIKCDQYWPSRGTETYGL--IQITLLDTVELATYTVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIRHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAVVQTEDQYQFCYRAGLEYLGSFDHYAT 1902          

HSP 2 Score: 284.648 bits (727), Expect = 2.409e-76
Identity = 278/1031 (26.96%), Postives = 452/1031 (43.84%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSG------SIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRHNLV--GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPI----NIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPV----TMVTLGNVQYNSDYQVGIKS 3222
            K+   P  Q  + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   T  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRSG      ++  ++  + D G YEC A N  G+  S    L +R   I P++   P + E+ PG  VN+TC A G+P P ++W+  ++   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +     S +      K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++  T E  PSSPP++V A   + T+I V+W  P E NG+I  Y VYY+ +    IN W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +      Y        G H       EE++  +   T YR+  L PN+LY+  LAAR + G+G S   ++ RT    P++ P  I   + S TSI + W      +++  I  + IK         VD  +    +I S+ ++T+      +Y++  LE    Y+I++ +   VG    S+P +      R    VPS PP  + +  +   +          ++W  P+    HG IR Y++ +  +  G       LK   L+   +E + T T +      L     Y  +V A  T   G   K  + +  +A    P  + I+    ++  I W PP VE   G ++ Y++ +    L   T    S    +     + +  LY F++ A  KVG G    +   + + +  +PP     NI     +   + +TW+  H N  +  G    Y L  + +DI   +     P+    T VTL  ++ ++ Y V +++
Sbjct:    8 KLTRTPVDQIGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNSVGEVATTTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDYLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRIAPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGVIEAIAQINVKALPKPPGTPMVTESTATSITLTWDSGNPE---PVSYYIIQHKPKSSEEQ---YKEIDGV-------ATTRYSVAGLSPYSEYEFRVVAVNN-IGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHINSWTKHNVADSQITTIGNLEPQKTYSVKVLAFTSVGDGPLSNDIQVITQTGVPSQPLNFKAEPESETSILLSWTPPRSDTISSYDLYYK-----EGDH------AEEQVITIDPATSYRLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQDIRCNSQSSTSILVSWLPPPVEKQNGKIMGYSIKYTG------VDTDDAKSHEILSISSETR------QYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILI-----RTDEDVPSGPPRKVEVEAVNSTS--------VKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEYDDT-TEHEMIISGLQPETAYSITVTAYTTKGDGARSKPKIVSTSAAVPGKPRLV-ISHTQMNTALIQWYPP-VETF-GPVIGYRLKFGRKDLDTLTTLEFSEKEEHFTATDIHKGALYIFKLSARNKVGYG----EEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQ--HPNLEERNGLLTKYTL--MYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRA 972          

HSP 3 Score: 169.088 bits (427), Expect = 4.704e-41
Identity = 263/1090 (24.13%), Postives = 454/1090 (41.65%), Query Frame = 1
Query:  157 IIQIILSNQI-VFAQWFRLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVR---------------IDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCT-AKGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKI-PVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDN---KNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRT-DYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSV---GSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTP-NLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            I + + SN +   A   RL V++E   PR G   I + PQ + V    TA   C   GNP   ++      K Y+    S    RI  ++ + G P+R                +C+  N SA  + +A  N+    + +    PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I  ++ ++  P        P    V      ++T T   GNP P   ++ Q H+P +            T + S+  L+  +E    +   NN   G     V  R  ++ P   P N+    +  T   + WE+  E +   + + +     ++D T        +I+ W   N     IT  + +L P   YSVKV+AF+ ++GD   S  I + T+   PS  P +  A  ++ TSI + W PP   +  I+ Y++YY     H   Q    +    + R+  L  N+ Y+ ++ A    G G  +       +  +P  PPQ  + R    +STSI + W PP  P +      +      +G  + T   K  EI  +   T  Y + +L   T Y I + A T+ G G  S+ + +RT+  VP+  P  ++V  ++ TS+ + WR  + N++   I  +++  +++++ E         V +     +  + ++ +E II+ L+    Y I + +    G    S P I       PG     P L I   Q+            A I W PP+ + G +  YR++    G ++L ++L     S K  E++ T T+       +  G +Y F ++A N    G E+   +S  E  P  +P +I     +S SV I+WQ P +E  NG+L  Y + Y    L +  I     P +    + GL+ +  Y  ++RA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y    +  +++       G  T   + N++  + Y   + ++G  N  G + +  TAK +
Sbjct:   78 IYECVASNSVGEVATTTRLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWF----KDYLPVDTSNNNGRIKQLR-SGGTPIRGALQIEQSEESDQGKYECVATN-SAGTRYSAPANLYVRVRRIA---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDV-------RQSANYTCVAMSTLGVIEAI-AQINVKALP------KPPGTPMVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKSSEEQYKEIDGVATTRYSVAGLSPYSEYEFRVVAVNNIGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVY---YTMDPT-------QHINSWTKHNVADSQIT-TIGNLEPQKTYSVKVLAFT-SVGDGPLSNDIQVITQTGVPSQ-PLNFKAEPESETSILLSWTPP--RSDTISSYDLYYKEG-DHAEEQVITIDPATSY-RLQGLKPNSLYYFRLAARAQVGLGASTAEISARTMQSKPSAPPQ--DIRCNSQSSTSILVSWLPP--PVEKQNGKIMGYSIKYTG--VDTDDAKSHEILSISSETRQYLLEQLEKWTQYRIIMIAYTDVGPGPESSPILIRTDEDVPSGPPRKVEVEAVNSTSVKVSWRSPVANKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEYDDTTE-HEMIISGLQPETAYSITVTAYTTKGDGARSKPKIVSTSAAVPGK----PRLVISHTQMN----------TALIQWYPPVETFGPVIGYRLK---FGRKDL-DTLTTLEFSEK--EEHFTATD-------IHKGALYIFKLSARNKVGYGEEIVKELSIPEEPPSGFPQNIHCDSTSSTSVLITWQHPNLEERNGLLTKYTLMYRDINLPHYPIEVPIVPADTTVTLTGLKPDTTYDVKLRAHTSKGPGPFSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SALPFKILYDDGKMAMEVD-------GRATQKLITNLKPETSYSFVLTNRG--NSAGGLQHRVTAKTA 1080          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Mouse
Match: Ptprd (protein tyrosine phosphatase, receptor type, D [Source:MGI Symbol;Acc:MGI:97812])

HSP 1 Score: 867.84 bits (2241), Expect = 0.000e+0
Identity = 401/604 (66.39%), Postives = 477/604 (78.97%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASF+DGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY  ALEYL SFD + +
Sbjct: 1303 NFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT 1890          

HSP 2 Score: 266.159 bits (679), Expect = 8.335e-71
Identity = 258/1018 (25.34%), Postives = 440/1018 (43.22%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSP--TSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRH-NLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDP-----PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKS 3222
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRSG++  ++  + D G YEC A N  G+  S    L +R   + P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NP      E  +  I      N+    K+I  I           Y+V  L PY+ Y  +V+A +  +G    S+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +                        +E+ I I P  T YR+  L PN+LY+  L+AR+  G+G S   ++ RT    P++P   D+   SP  TSI + W+     +++  I+ + +K         VD  +    +I  +P      SD  +Y++  LE    Y+I + +    G     +  +++T     VPS PP  + +          +      ++W  P+    HG IR Y++ +  +   +   + + +  +     +  ++G    T          Y  +V A  T   G   K   VST  + P    + I+ T +  ++  I W PP+  +  G L  Y++ +    ++  T    S    +     + +   Y F++ A  KVG G           + +P+      P N+ +       ++++W+   L+  N + +  + + Y    +P  +     L V   T +TL  ++ ++ Y V +++
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNP------EPVSYYIIQHKPKNSEEPYKEIDGI-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQ----------GEEQRITIEPG-TSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQ-DISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYA------AVDGEDFKPHEILGIP------SDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRT--DEDVPSGPPRKVEVE--------AVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQDMIISGLQPETS---------YSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQM--NTALIQWHPPV--DTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGE-----EMVKEISVPEEIPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGV-ITKYTLLYRDINVP--LLPMEHLIVPADTSMTLTGLKSDTTYDVKVRA 974          

HSP 3 Score: 166.007 bits (419), Expect = 2.556e-40
Identity = 252/1078 (23.38%), Postives = 445/1078 (41.28%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM-------KKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA--------KGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAV--QVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTD--------LRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQ---HVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXX-XXXXXXISGKHIPTLTNKEEEIKILP-DRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYAL-IEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            RL V++E   PR G   I + PQ + V    TA   C   GNP   ++   + +          +  + SG  L+I   + +D    + +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I          IT + + +P      PG  V    TA         GNP P   ++ Q H+P N            T + S+  L+  ++    +   NN   G     V  Q   +     P ++    +  T   + W++  E                 +  + G +    + P    N  + +NV D        L P   YSVKV+AF+ ++GD   S  I + T+   P   P +  A  ++ TSI + W PP   +  I  Y + Y        +Q ++   T +     R+  L  N+ Y+ +++A +  G G  +       +  +P  PPQ  +      +STSI + W PP +  +  ++    LKY  + G+       K  EI  +P D T Y + +L   T Y I++ A T+ G G  S ++ +RT+  VP+  P  ++V  ++ T++ + WR  + N++   I  +++  +K+++ E         V +          +D  + II+ L+   +Y + + +  + G  A     +V T  G +   P L I   Q+            A I W PP+++ G ++ YR++      +  +E L     S K  E + T T+       +  G  Y F ++A N    G E+   +S  E  P  +P ++   G TS SV +SWQPP++   NG++  Y + Y    +    +     P   ++ + GL+ +  Y  +VRA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y    + ++++       G  T   + N++    Y   + ++G  N  G + +  TAK +
Sbjct:  112 RLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSG-ALQIEQSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDV-------RQSANYTCVAMSTLGVIEAIAQ--------ITVKALPKP------PGTPVVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP----------------NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPP--RSDTIASYELVYRDG-----DQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQ--DISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDF-----KPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVML----------ADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTT-GAVPGKPRLVINHTQMN----------TALIQWHPPVDTFGPLQGYRLKFG----RKDMEPLTTLEFSEK--EDHFTATD-------IHKGASYVFRLSARNKVGFGEEMVKEISVPEEIPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGVITKYTLLYRDINVPLLPMEHLIVPADTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SAMPFKILYDDGKMVEEVD-------GRATQKLIVNLKPEKSYSFVLTNRG--NSAGGLQHRVTAKTA 1082          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Mouse
Match: Ptprd (protein tyrosine phosphatase, receptor type, D [Source:MGI Symbol;Acc:MGI:97812])

HSP 1 Score: 867.07 bits (2239), Expect = 0.000e+0
Identity = 401/604 (66.39%), Postives = 477/604 (78.97%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASF+DGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY  ALEYL SFD + +
Sbjct: 1325 NFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT 1912          

HSP 2 Score: 256.914 bits (655), Expect = 5.678e-68
Identity = 266/1034 (25.73%), Postives = 443/1034 (42.84%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---------GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKL------EIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSP--TSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRHNLV--GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDP-----PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKS 3222
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRS         G++  ++  + D G YEC A N  G+  S    L      E+R  P  P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  I           Y+V  L PY+ Y  +V+A +  +G    S+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +                        +E+ I I P  T YR+  L PN+LY+  L+AR+  G+G S   ++ RT    P++P   D+   SP  TSI + W+     +++  I+ + +K         VD  +    +I  +P      SD  +Y++  LE    Y+I + +    G     +  +++T     VPS PP  + +          +      ++W  P+    HG IR Y++ +  +  G       LK   L+   +E + T T +      L     Y  +V A  T   G   K   VST  + P    + I+ T +  ++  I W PP+  +  G L  Y++ +    ++  T    S    +     + +   Y F++ A  KVG G           + +P+      P N+ +       ++++W+   L+  N + +  + + Y    +P  +     L V   T +TL  ++ ++ Y V +++
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVP--PRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEEPYKEIDGI-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQ----------GEEQRITIEPG-TSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQ-DISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYA------AVDGEDFKPHEILGIP------SDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRT--DEDVPSGPPRKVEVE--------AVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDT-TEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQM--NTALIQWHPPV--DTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGE-----EMVKEISVPEEIPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGV-ITKYTLLYRDINVP--LLPMEHLIVPADTSMTLTGLKSDTTYDVKVRA 996          

HSP 3 Score: 162.155 bits (409), Expect = 4.459e-39
Identity = 253/1089 (23.23%), Postives = 445/1089 (40.86%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLY----------NGMKKYV-------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNV-TDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA--------KGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAV--QVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTD--------LRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQ---HVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXX-XXXXXXISGKHIPTLTNKEEEIKILP-DRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYAL-IEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            RL V++E   PR G   I + PQ + V    TA   C   GNP   ++             NG  K +        PI   L +     +  +    + +C+  N SA  + +A  N+     +++    PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I          IT + + +P      PG  V    TA         GNP P   ++ Q H+P N            T + S+  L+  ++    +   NN   G     V  Q   +     P ++    +  T   + W++  E                 +  + G +    + P    N  + +NV D        L P   YSVKV+AF+ ++GD   S  I + T+   P   P +  A  ++ TSI + W PP   +  I  Y + Y        +Q ++   T +     R+  L  N+ Y+ +++A +  G G  +       +  +P  PPQ  +      +STSI + W PP +  +  ++    LKY  + G+       K  EI  +P D T Y + +L   T Y I++ A T+ G G  S ++ +RT+  VP+  P  ++V  ++ T++ + WR  + N++   I  +++  +K+++ E         V +     +  + ++ ++ II+ L+   +Y + + +  + G  A     +V T  G +   P L I   Q+            A I W PP+++ G ++ YR++      +  +E L     S K  E + T T+       +  G  Y F ++A N    G E+   +S  E  P  +P ++   G TS SV +SWQPP++   NG++  Y + Y    +    +     P   ++ + GL+ +  Y  +VRA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y       D +    +D G  T   + N++    Y   + ++G  N  G + +  TAK +
Sbjct:  112 RLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIE----QSEESDQGKYECVATN-SAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDV-------RQSANYTCVAMSTLGVIEAIAQ--------ITVKALPKP------PGTPVVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP----------------NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPP--RSDTIASYELVYRDG-----DQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQ--DISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDF-----KPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTE-HDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTT-GAVPGKPRLVINHTQMN----------TALIQWHPPVDTFGPLQGYRLKFG----RKDMEPLTTLEFSEK--EDHFTATD-------IHKGASYVFRLSARNKVGFGEEMVKEISVPEEIPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGVITKYTLLYRDINVPLLPMEHLIVPADTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SAMPFKILY------DDGKMVEEVD-GRATQKLIVNLKPEKSYSFVLTNRG--NSAGGLQHRVTAKTA 1104          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Mouse
Match: Ptprd (protein tyrosine phosphatase, receptor type, D [Source:MGI Symbol;Acc:MGI:97812])

HSP 1 Score: 866.685 bits (2238), Expect = 0.000e+0
Identity = 401/604 (66.39%), Postives = 477/604 (78.97%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASF+DGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY  ALEYL SFD + +
Sbjct:  667 NFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT 1254          

HSP 2 Score: 183.341 bits (464), Expect = 8.327e-46
Identity = 144/502 (28.69%), Postives = 227/502 (45.22%), Query Frame = 1
Query:  865 PGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSG------LSAPFIFDIVKTRPGNI 2340
            PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  I           Y+V  L PY+ Y  +V+A +  +G    S+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +                        +E+ I I P  T YR+  L PN+LY+  L+AR+  G+G S T  +              V+ +  TS+ + W    +N  S   FKI     K +E VD                       + +I +L+  ++Y  VL + G+S       ++A    D+++T+P  I
Sbjct:    2 PGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEEPYKEIDGI-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQ----------GEEQRITIEPG-TSYRLQGLKPNSLYYFRLSARSPQGLGAS-TAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIP-ENYNSAMPFKILYDDGKMVEEVDGRAT-------------------QKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFI 457          

HSP 3 Score: 62.003 bits (149), Expect = 1.070e-8
Identity = 64/267 (23.97%), Postives = 117/267 (43.82%), Query Frame = 1
Query: 2611 YEFSVAAMNTADIGLEVK-LNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK--NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRV 3399
            YEF V A+N    G   + +   T E AP S P  +    ++S ++ + W+ P  E  NG +  Y+V Y     +  N  ++     +    I  L     Y+ +V AFT +G GP SSD+   T   +P  P+N +A   +E  I ++W    ++ I        Y L     D      + + P T   L  ++ NS Y   + ++      GL    +TA+IS    ++ +   +   +  ++ S+ + W+ P+ +++   F++
Sbjct:  142 YEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIAS------YELVYRDGDQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQ---GL--GASTAEISAR-TMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKI 394          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Mouse
Match: Ptprd (protein tyrosine phosphatase, receptor type, D [Source:MGI Symbol;Acc:MGI:97812])

HSP 1 Score: 866.3 bits (2237), Expect = 0.000e+0
Identity = 401/604 (66.39%), Postives = 477/604 (78.97%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASF+DGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY  ALEYL SFD + +
Sbjct:  908 NFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT 1495          

HSP 2 Score: 237.269 bits (604), Expect = 2.933e-62
Identity = 203/721 (28.16%), Postives = 317/721 (43.97%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKL------EIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSG------LSAPFIFDIVKTRPGNI 2340
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRS   G++  ++  + D G YEC A N  G+  S    L      E+R  P  P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  I           Y+V  L PY+ Y  +V+A +  +G    S+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +                        +E+ I I P  T YR+  L PN+LY+  L+AR+  G+G S T  +              V+ +  TS+ + W    +N  S   FKI     K +E VD                       + +I +L+  ++Y  VL + G+S       ++A    D+++T+P  I
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVP--PRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEEPYKEIDGI-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQ----------GEEQRITIEPG-TSYRLQGLKPNSLYYFRLSARSPQGLGAS-TAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIP-ENYNSAMPFKILYDDGKMVEEVDGRAT-------------------QKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFI 698          

HSP 3 Score: 62.3882 bits (150), Expect = 8.021e-9
Identity = 64/267 (23.97%), Postives = 118/267 (44.19%), Query Frame = 1
Query: 2611 YEFSVAAMNTADIGLEVK-LNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK--NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRV 3399
            YEF V A+N    G   + +   T E AP S P  +    ++S ++ + W+ P  E  NG +  Y+V Y     +  N  ++     +    I  L     Y+ +V AFT +G GP SSD+   T   +P  P+N +A   +E  I ++W    ++ I        Y L     D      + + P T   L  ++ NS Y   + ++   +  GL    +TA+IS    ++ +   +   +  ++ S+ + W+ P+ +++   F++
Sbjct:  383 YEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIAS------YELVYRDGDQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSAR---SPQGL--GASTAEISAR-TMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKI 635          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Mouse
Match: Ptprd (protein tyrosine phosphatase, receptor type, D [Source:MGI Symbol;Acc:MGI:97812])

HSP 1 Score: 866.3 bits (2237), Expect = 0.000e+0
Identity = 401/604 (66.39%), Postives = 477/604 (78.97%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASF+DGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY  ALEYL SFD + +
Sbjct:  915 NFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT 1502          

HSP 2 Score: 236.498 bits (602), Expect = 6.087e-62
Identity = 203/724 (28.04%), Postives = 317/724 (43.78%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSG------SIFFDRLLKEDSGIYECRAINPVGSILSIKMKL------EIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSG------LSAPFIFDIVKTRPGNI 2340
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRSG      ++  ++  + D G YEC A N  G+  S    L      E+R  P  P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  I           Y+V  L PY+ Y  +V+A +  +G    S+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +                        +E+ I I P  T YR+  L PN+LY+  L+AR+  G+G S T  +              V+ +  TS+ + W    +N  S   FKI     K +E VD                       + +I +L+  ++Y  VL + G+S       ++A    D+++T+P  I
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVP--PRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEEPYKEIDGI-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQ----------GEEQRITIEPG-TSYRLQGLKPNSLYYFRLSARSPQGLGAS-TAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIP-ENYNSAMPFKILYDDGKMVEEVDGRAT-------------------QKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFI 701          

HSP 3 Score: 62.7734 bits (151), Expect = 6.727e-9
Identity = 64/267 (23.97%), Postives = 118/267 (44.19%), Query Frame = 1
Query: 2611 YEFSVAAMNTADIGLEVK-LNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK--NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRV 3399
            YEF V A+N    G   + +   T E AP S P  +    ++S ++ + W+ P  E  NG +  Y+V Y     +  N  ++     +    I  L     Y+ +V AFT +G GP SSD+   T   +P  P+N +A   +E  I ++W    ++ I        Y L     D      + + P T   L  ++ NS Y   + ++   +  GL    +TA+IS    ++ +   +   +  ++ S+ + W+ P+ +++   F++
Sbjct:  386 YEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIAS------YELVYRDGDQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSAR---SPQGL--GASTAEISAR-TMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKI 638          
BLAST of Receptor type tyrosine protein phosphatase vs. UniProt/SwissProt
Match: sp|P16621|LAR_DROME (Tyrosine-protein phosphatase Lar OS=Drosophila melanogaster OX=7227 GN=Lar PE=1 SV=2)

HSP 1 Score: 1100.5 bits (2845), Expect = 0.000e+0
Identity = 731/2112 (34.61%), Postives = 1083/2112 (51.28%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMK------KY-VIPIPSGL-MLRIPDVKLT-DGKPVRIDCIVRNPSAEE-KKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDV-EVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGK-HIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSP-IGIDVRTLSPTSIAIRW--------------------RKGMDNEESIS-----------------SFKIKVIKLKSIETVDNSNEMHVQIQS--------VPAKTKNQSDIYEYIINDLETGQNYKIVLWSV--------GSSGLSAPFIFDIVKTRPGNIV---PSPPLNIRLNQLRQKTESGLTLLLA--------------------------DIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAY---FTYGL---KNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEII-LVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSK-----YSFESLQSASKPIS-YSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACI------------FTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +II  PQ+Q V +G  A F+C   G+P   +    NG K      +Y V+  P G+ +LRI  V+   D  P   +C+  N   +     A L + +  K  P GFP         V +VG  + M C   G       W K+   +D+S PR + L+ G +  +   +ED G YEC A N +G+  S    L ++   + P +   P+ + EV  G  +NL+C A G+P P ++W+  ++   P N++    ++L L +I E A+Y C A +++G I     V+V+ +P  P ++    +  T  ++ W      DL        +      N      +I  I         + Y V  L PYT Y   VIA +  +G   PS      T E    S P++V     + +++ + W PP   NG++T Y VYY+ N   P   W         +  +++L  +  Y ++V A  S G GP+S P  +  + GVP QP NFR   I  T++ L W+ P   S+ ++   +      + + H   ++N E           Y +  L+P+TLY+I LAAR++ G G +   + VRT+  VP +P   I     S T+I++ W                      G +++E+ +                  +KI V+   S+     S+ + ++ Q         V A   N + I+      LE  +N  I  + +        G   L+ PF FD+V T   N+    P    +I++  L +K +   +  +                           ++ W+ P  ++G +R YR+R  +       ++LK   LS     K          F  L  G  YEF VA  N   IG E      T E  P   P +I I   T   + ++W PP  E+ NGI+  Y V +     +GL   +N T+R        A+   L+EN  Y F+VRA+TK G GP+S  +   T   +   P++++A   +E   ++ WE   T+  K++G+KI+Y +  + +D++   T  VG      L N++  + Y V I ++   N  G +S   T +I    V  +L    +       SM + W  P     ++ ++++ +    +    G  +   +   P+    +  Y+K    + ++SP   Y+++V  +         Y      +  T MA P+ +  P+   +VN   + + L   + +E  G I  YYL++   +   K+N  K      + + L   +KP    +P + A+F     ++    +F +G       +      T+  L R      +K Y++F+RA +            F+E  S    +  P  +       N+   P ++    K + ++    ++  ++    I   ++ V C +KRRR  +   +P +  +      +  + +   +GP    P+        DM    + NF+   +  HPPIP    A++I  LK+NDN KF++EYESI+PG  FTW  SNLE NK KNRYANV AYDHSRV L  +  + GSDYINANYCDGYRK NAY+ATQGPL ETF  FWRM WE + A IVMMT+LEER R+KCDQYWPTRG+E Y +  ++I   ET ELA Y++R F L ++      G  + R++   QFT WPDHGVPD   P L F++R R+  P +SGP++VHCSAGVGRTG YIV+DS L +++HEK++D+YG V+ LRAQRNYMVQTE+QY+FI+DA+LEA +CG TEV  R+LH H+ KL        +T   +  +GME+EFK LS +     +F TANLP N+ KNRL++ILPYE+ RV L PI   +GSDY+NASFIDGYR + AYIA QGP+ +   DFWRMLW+HNS+IVVML++L+EMGREKC QYWP ERS  +   +V+P+ EYNMP + LREF+V  +  +  +RT+RQFQF+DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGR+GVF+ LSIVL+RM+ EG +D+FQTVR+LR QRP MVQTEDQY FCY  ALEYL SFD +
Sbjct:   37 EIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISILRIEPVRAGRDDAP--YECVAENGVGDAVSADATLTIYEGDK-TPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL-----QYYVIQYKPKNANQAFSEISGI-------ITMYYVVRALSPYTEYEFYVIAVNN-IGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHKRISNSEA----------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKD-----QALKEEMLSGPQMTKK--------RFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRK-------AVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLLGYKIFYTMTAV-EDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAAR-FKNGLGRLSEKVTVRIKPEDVPLNLRAHDVS----THSMTLSWSPPIRLTPVN-YKISFDAMKVFVDSQGFSQ---TQIVPKREIILKHYVK-THTINELSPFTTYNVNVSAI----PSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILP--QASEEYGPISHYYLVV---VPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFP----QRSIPFTFHLGSGDDYHNF------TNRKLER------EKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREA-PPGERPHRPDPNWPAEPEVSVNRNKDEPEIL--WVVLPLMVSTFIVSTALIVLCVVKRRR--QPCKTPDQAAVT-----RPLMAADLGAGPTPSDPV--------DMR---RLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTIT--ETQELATYSIRTFQLCRQ------GFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLL-------ITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDA-RDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNY 2027          
BLAST of Receptor type tyrosine protein phosphatase vs. UniProt/SwissProt
Match: sp|Q64487|PTPRD_MOUSE (Receptor-type tyrosine-protein phosphatase delta OS=Mus musculus OX=10090 GN=Ptprd PE=1 SV=3)

HSP 1 Score: 867.07 bits (2239), Expect = 0.000e+0
Identity = 401/604 (66.39%), Postives = 477/604 (78.97%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASF+DGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY  ALEYL SFD + +
Sbjct: 1325 NFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHYAT 1912          

HSP 2 Score: 256.914 bits (655), Expect = 3.972e-67
Identity = 266/1034 (25.73%), Postives = 443/1034 (42.84%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---------GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKL------EIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVR-ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSP--TSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRHNLV--GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDP-----PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKS 3222
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRS         G++  ++  + D G YEC A N  G+  S    L      E+R  P  P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  I           Y+V  L PY+ Y  +V+A +  +G    S+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +                        +E+ I I P  T YR+  L PN+LY+  L+AR+  G+G S   ++ RT    P++P   D+   SP  TSI + W+     +++  I+ + +K         VD  +    +I  +P      SD  +Y++  LE    Y+I + +    G     +  +++T     VPS PP  + +          +      ++W  P+    HG IR Y++ +  +  G       LK   L+   +E + T T +      L     Y  +V A  T   G   K   VST  + P    + I+ T +  ++  I W PP+  +  G L  Y++ +    ++  T    S    +     + +   Y F++ A  KVG G           + +P+      P N+ +       ++++W+   L+  N + +  + + Y    +P  +     L V   T +TL  ++ ++ Y V +++
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVP--PRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEEPYKEIDGI-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQ----------GEEQRITIEPG-TSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQ-DISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYA------AVDGEDFKPHEILGIP------SDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRT--DEDVPSGPPRKVEVE--------AVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDT-TEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQM--NTALIQWHPPV--DTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGE-----EMVKEISVPEEIPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGV-ITKYTLLYRDINVP--LLPMEHLIVPADTSMTLTGLKSDTTYDVKVRA 996          

HSP 3 Score: 162.155 bits (409), Expect = 3.119e-38
Identity = 253/1089 (23.23%), Postives = 445/1089 (40.86%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLY----------NGMKKYV-------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNV-TDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA--------KGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAV--QVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTD--------LRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQ---HVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXX-XXXXXXISGKHIPTLTNKEEEIKILP-DRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYAL-IEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            RL V++E   PR G   I + PQ + V    TA   C   GNP   ++             NG  K +        PI   L +     +  +    + +C+  N SA  + +A  N+     +++    PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I          IT + + +P      PG  V    TA         GNP P   ++ Q H+P N            T + S+  L+  ++    +   NN   G     V  Q   +     P ++    +  T   + W++  E                 +  + G +    + P    N  + +NV D        L P   YSVKV+AF+ ++GD   S  I + T+   P   P +  A  ++ TSI + W PP   +  I  Y + Y        +Q ++   T +     R+  L  N+ Y+ +++A +  G G  +       +  +P  PPQ  +      +STSI + W PP +  +  ++    LKY  + G+       K  EI  +P D T Y + +L   T Y I++ A T+ G G  S ++ +RT+  VP+  P  ++V  ++ T++ + WR  + N++   I  +++  +K+++ E         V +     +  + ++ ++ II+ L+   +Y + + +  + G  A     +V T  G +   P L I   Q+            A I W PP+++ G ++ YR++      +  +E L     S K  E + T T+       +  G  Y F ++A N    G E+   +S  E  P  +P ++   G TS SV +SWQPP++   NG++  Y + Y    +    +     P   ++ + GL+ +  Y  +VRA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y       D +    +D G  T   + N++    Y   + ++G  N  G + +  TAK +
Sbjct:  112 RLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIE----QSEESDQGKYECVATN-SAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDV-------RQSANYTCVAMSTLGVIEAIAQ--------ITVKALPKP------PGTPVVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP----------------NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPP--RSDTIASYELVYRDG-----DQGEEQRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQ--DISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDF-----KPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTE-HDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTT-GAVPGKPRLVINHTQMN----------TALIQWHPPVDTFGPLQGYRLKFG----RKDMEPLTTLEFSEK--EDHFTATD-------IHKGASYVFRLSARNKVGFGEEMVKEISVPEEIPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGVITKYTLLYRDINVPLLPMEHLIVPADTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SAMPFKILY------DDGKMVEEVD-GRATQKLIVNLKPEKSYSFVLTNRG--NSAGGLQHRVTAKTA 1104          
BLAST of Receptor type tyrosine protein phosphatase vs. UniProt/SwissProt
Match: sp|P23468|PTPRD_HUMAN (Receptor-type tyrosine-protein phosphatase delta OS=Homo sapiens OX=9606 GN=PTPRD PE=1 SV=2)

HSP 1 Score: 864.759 bits (2233), Expect = 0.000e+0
Identity = 401/604 (66.39%), Postives = 476/604 (78.81%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD+I  LK NDN KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+LS +  IPGSDY+NANY DGYRKQNAYIATQG LPETF  FWRM+WE R A +VMMTKLEER RVKCDQYWP+RG+E +    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQF Y  ALEYL SFD + +
Sbjct: 1325 NFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGL--VQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT 1912          

HSP 2 Score: 268.47 bits (685), Expect = 1.136e-70
Identity = 272/1034 (26.31%), Postives = 449/1034 (43.42%), Query Frame = 1
Query:  268 PQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---------GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKL------EIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSP--TSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRHNLV--GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDP-----PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKS 3222
            P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + +P GFP   +     V +  +   M C   G    +  WFKD  P+D S    R   LRS         G++  ++  + D G YEC A N  G+  S    L      E+R  P  P++   P + E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L L D+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE        +  I      N+    K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS+ ++ +T E  PSS P+ V A   + T+I V+W  P E NG+I  Y VYY+ +    +N W K       +  I +L    TY +KV A  S G GP+S    +I + GVP QP NF+    + TSI L W+PP+  +               G+H      +E+ I I P  T YR+  L PN+LY+  LAAR+  G+G S   ++ RT    P++P   D+   SP  TSI + W+     +++  I+ + IK         VD  ++   +I  +P      SD  +Y++  LE    Y+I + +    G     +  +++T     VPS PP  + +  +   +          ++W  P+    HG IR Y++ +  +  G       LK   L+   +E + T T +      L     Y  +V A  T   G   K   VST  + P    + I+ T +  ++  I W PP+  +  G L  Y++ +    ++  T    S    +     + +   Y F++ A  KVG G           + +P+      P N+ +       ++++W+   L+  N I +  + + Y    IP  +     L V   T +TL  ++ ++ Y V +++
Sbjct:   30 PVDQTGVSGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNNVGEISVSTRLTVLREDQ-IPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVP--PRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP------VSYYIIQHKPKNSEELYKEIDGV-------ATTRYSVAGLSPYSDYEFRVVAVNN-IGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYK-----DGEH-----GEEQRITIEPG-TSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQ-DISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT------AVDGEDDKPHEILGIP------SDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRT--NEDVPSGPPRKVEVEAVNSTS--------VKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDT-TEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQM--NTALIQWHPPV--DTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGE-----EMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGI-ITKYTLLYRDINIP--LLPMEQLIVPADTTMTLTGLKPDTTYDVKVRA 996          

HSP 3 Score: 163.31 bits (412), Expect = 1.497e-38
Identity = 250/1085 (23.04%), Postives = 442/1085 (40.74%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLY----------NGMKKYV-------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNV-TDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA--------KGNPPPQLRWLTQYHRPIND----------LTDKESILLLTDITEPASYICRANN-SMGVIQHAV--QVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTD--------LRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFP---IIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILP-DRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTP-NLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKIS 3279
            RL V++E   PR G   I + PQ + V    TA   C   GNP   ++             NG  K +        PI   L +     +  +    + +C+  N SA  + +A  N+     +++    PRF +    +    G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I +I          IT + + +P      PG  V    TA         GNP P   ++ Q H+P N            T + S+  L+  ++    +   NN   G     V  Q   +     P ++    +  T   + W++  E                 +  + G +    + P    N  + +NV D        L P   YSVKV+AF+ ++GD   S  I + T+   P   P +  A  ++ TSI + W PP   +  I +Y + Y ++ +H   Q    E    + R+  L  N+ Y+ ++ A +  G G  +       +  +P  PPQ  +      +STSI + W PP +       + ++    I    +    +K  EI  +P D T Y + +L   T Y I++ A T+ G G  S ++ +RT   VP+  P  ++V  ++ TS+ + WR  + N++   I  +++  +++++ E         V +     +  + ++ ++ II+ L+   +Y + + +  + G  A     +V T  G +   P L I   Q+            A I W PP+++ G ++ YR++      +  +E L     S K  E + T T+       +  G  Y F ++A N    G E+   +S  E  P  +P ++   G TS SV +SWQPP++   NGI+  Y + Y    +    +     P +    + GL+ +  Y  +VRA T  G GP+S  V FRT+ +      N     + +  + ++WE+    N   + FKI Y    + ++++       G  T   + N++    Y   + ++G  N  G + +  TAK +
Sbjct:  112 RLTVLREDQIPR-GFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIE----QSEESDQGKYECVATN-SAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDV-------RQSANYTCVAMSTLGVIEAIAQ--------ITVKALPKP------PGTPVVTESTATSITLTWDSGNPEPVSYYIIQ-HKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP----------------NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTPP--RSDTIANYELVY-KDGEHGEEQRITIEPGTSY-RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQ--DISCTSPSSTSILVSWQPPPV----EKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTE-HDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTT-GAVPGKPRLVINHTQMN----------TALIQWHPPVDTFGPLQGYRLKFG----RKDMEPLTTLEFSEK--EDHFTATD-------IHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYN-SAMPFKILYDDGKMVEEVD-------GRATQKLIVNLKPEKSYSFVLTNRG--NSAGGLQHRVTAKTA 1104          
BLAST of Receptor type tyrosine protein phosphatase vs. UniProt/SwissProt
Match: sp|A7MBJ4|PTPRF_BOVIN (Receptor-type tyrosine-protein phosphatase F OS=Bos taurus OX=9913 GN=PTPRF PE=2 SV=1)

HSP 1 Score: 855.514 bits (2209), Expect = 0.000e+0
Identity = 393/604 (65.07%), Postives = 475/604 (78.64%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            N++   +  HPPIP   LAD I  LK ND  KF++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRV+L++++ +PGSDYINANY DGYRKQNAYIATQGPLPET   FWRMVWE R A +VMMT+LEE+ RVKCDQYWP RG+E Y    + +  L+TVELA YT+R F+L K      +GS E R++  FQF  WPDHGVP+   P+L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +++HEK VD+YG V+ +RAQRNYMVQTE+QYVFI++ALLEA++CG+TEV  R+L+AH+ KL Q        P  +  T MELEFK L+       +F +ANLP N+ KNRL+NI+PYE  RVCLQPIR  +GSDYINASF+DGYR QKAYIATQGPLA +  DFWRMLW+HNS+I+VML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP++GE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV+ LR QRP MVQTEDQYQ CY  ALEYL SFD + +
Sbjct: 1311 NYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETYGL--IQVTLLDTVELATYTVRTFALYK------SGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRAQRNYMVQTEDQYVFIHEALLEAAMCGHTEVPARNLYAHIQKLGQ-------VPPGESVTAMELEFKLLANSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTRLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1898          

HSP 2 Score: 263.077 bits (671), Expect = 4.512e-69
Identity = 257/1093 (23.51%), Postives = 464/1093 (42.45%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKY-----VIPIP--SGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLD--LSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPI--NDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEE--EIKILPDRT-DYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRW-------RKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPINS--HGTIRAYRIRH-NLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDP-----PINIEASRINENQIKVTWE--LSHTNNIKVVGFKIYYCLQTIPKDIESCNTL-DVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRVTING 3411
             +  P+ QT L G  A F CQ  G P   ++ +  G K       VI     +G +LRI  +++   + +  +C   N   E   +A L+V +  + LP GFP   +     V +  +   M C   G    + +WFKD  P+D   S  R   LRSG++  +   + D G YEC A N  G+  S    L +R   + P++   P   EV PG  VNLTC A G P P ++W+         +++    ++L L+++   A+Y C A +S+G+I+   QV VK +PK P+++       T   ++W+    +  P   + +       +     +  +              Y++  L P++ Y+ +V+A + ++G   PS+ +   T E  PSSPP+ V A   + +++ V+W PP E NG +  Y VYY+ + + P++ W K  T    +  +  L    TY ++V A  + G GP S    +  + GVP QP +F+    + T I L W  PPQ              + I    +     ++E  + K+  D T  Y + +L P+TLY   LAAR+E GVGV + T+  RT    P++ P  +   ++  T++ + W       R G+  + S+           + E VD  +     +  +  +  +  D+       LE    Y++ + +   VG    S+P +      R    VPS PP  + +  L              ++W  P+ S  HG IR Y++ +  L   +     + +  +  +  E  ++G    T          Y  +VAA  T   G   K  + T   A    P  + ++    ++  + W PP  +   G L+ Y++ Y        +       + +  + GL +   Y F++ A  + G G       F   +  P+      P N+    +  +  ++ W+  +    N ++  + + Y      +DI S   L +V   T +TL  ++ ++ Y + ++++       L  +I +  +     +  +   + + E  ++ S+ + W+ P ++ +   FR+  NG
Sbjct:   35 FVKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAI-YECTATNSLGEINTSAKLSVLE-EEQLPLGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPAASNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSG--NSEPVSYYGIQYRPAGAEGPFQEVDGVATTR----------YSIGGLSPFSEYAFRVLAVN-SIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVDSDTRIQLSWLLPPQ--------------ERIVKYELVYWAAEDEGQQHKVTFDPTSSYTVEDLKPDTLYRFQLAARSELGVGVFTPTIEARTAQSTPSAPPQKVTCVSVGSTTVRVSWVPPPADSRNGVITQYSV-----------AYEAVDGEDRGRHVVDGI-GREHSSWDLV-----GLEKWTEYRVWVRAHTDVGPGPESSPVL-----VRTDEDVPSGPPRKVEVEPLNSTA--------VRVSWKLPVPSKQHGQIRGYQVTYVRLENGEPRGAPIIQDVMLAEAQETTISGLTPET---------TYSITVAAYTTKGDGARSKPKIVTTTGAVPGRPTMM-VSTTAMNTALLQWHPP--KELPGELLGYRLQYRRADEARPSTIDFGKDDQHFTVTGLHKGATYIFRLTAKNRAGLGE-----EFEKEITTPEDVPSGFPQNLRVIGLTTSTTELIWDPPVLAERNGRITNYTVVY------RDINSQQELQNVTADTHLTLSGLKPDTTYDIKVRARTSKGAGPLSPSIQSRTMP----VEQVFAKNFRVEAAMKTSVLLSWEVPDSYKSAVPFRILYNG 1041          
BLAST of Receptor type tyrosine protein phosphatase vs. UniProt/SwissProt
Match: sp|A4IFW2|PTPRF_DANRE (Receptor-type tyrosine-protein phosphatase F OS=Danio rerio OX=7955 GN=ptprf PE=2 SV=1)

HSP 1 Score: 853.588 bits (2204), Expect = 0.000e+0
Identity = 391/604 (64.74%), Postives = 474/604 (78.48%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            N++   + +HPPI    LAD+I  LK ND  +F++EYESIDPG  FTW  SNLE+NKPKNRYANVIAYDHSRVVL+ ++ +PGSDYIN+NY DGYRKQNAYIATQGPLPET   FWRM+WE R + IVMMT+LEE+ RVKCDQYWP RG+E Y    + +  L+ VELA Y++R F+L K      NGS E R+V  FQF  WPDHGVP+   P+L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +++HEK VD+YG V+ +R+QRNYMVQTE+QY+FI++ALLEA+ CGNTEV  R+L+AH+ KL QP        + +  T MELEFK L+       +F +ANLP N+ KNRL+NI+P+E+ RVCLQPIR  +GSDYINAS IDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP++GE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VDLFQTV+ LR QRP MVQTEDQYQ CY  ALEYL SFD + +
Sbjct: 1322 NYQTPGMREHPPISVSELADHIERLKANDALRFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINSNYIDGYRKQNAYIATQGPLPETLSDFWRMIWEQRASTIVMMTRLEEKSRVKCDQYWPIRGTETYGM--IQVTMLDAVELATYSVRTFALYK------NGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLTQP-------SAGETVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1909          

HSP 2 Score: 288.886 bits (738), Expect = 5.607e-77
Identity = 278/1085 (25.62%), Postives = 475/1085 (43.78%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKY-----VIPIP--SGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLS-EPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND--LTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWS-PPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPD-RTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRK--GMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVP-SPPLNIRLNQLRQKTESGLTLLLADIAWDPPINS--HGTIRAYRIRHNLV------GPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQG-PWSSDVNFRTVVLLPDP-PINIEASRINENQIKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIES-CNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVR-SMEIQWQKPKTHDNLSKFRVTIN 3408
             + +P+ QT + G  A F CQ  G P   ++ +  G K       VI     SG +LRI  ++    + +  +C   N   E   +A L V + ++ +P+GFP   +     V +  +   M C   G    +  WFKD  P+D++   R   LRSG++  +   + D G YEC A N  G+  S    L +R   + P++   P + EV PG  VNLTC A G P P ++W+T       D  +    ++L LT+I +  +Y C A +S+G+I+   QV VK +PK P ++T      T   ++W+  NPE   P   + +     + D     +  +              Y++  L PY+ Y  +V+A +  +G   PS+ +   T E  PSSPP  V A   + +++ V+W PP E NG+I  Y +YY+ +L  P++ WQK  T    +  I+ L T  TY ++V    S G GP S+   +  + GVP QP +F       T I L W  P Q P     L Y                + + +I +  D    Y +  L P+TLY  SLAAR+E G GV ++ +  RT    P++ P  + + +LS TSI + W          +I  + +      S + V+  +    ++  + A      D    ++  LE    Y++  W    + +        V+ R    VP +PP  + +  L              + W PP++   HG IR Y++ ++ +      G  N+++ +       K+ E     T Y      L     Y  +VAA  T   G   K  V T   A    P  I I+    ++  I WQPP  ++  G L+ Y++ Y     +N  IR  S  + +  +  L +   Y+F + A  + G G  +  D+   T   +P   P+N++   +  +  ++TWE   LS  N  +++ + + Y      +DI S  N+ +    T +T+  ++ ++ Y + +++        +  +I +  +S  P       +S   +  ++ S+ + W+ P+ + +   F++  N
Sbjct:   37 FVRSPEDQTGISGGVASFVCQAAGEPKPRITWMKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAI-YECTATNSLGEINTSAKLTVLEENQ-IPHGFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGRIKQLRSGALQIENSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELTNIRQSTNYTCVAISSLGMIEATAQVSVKALPKPPTSLTVTETTATSVTLTWDSGNPE---PVSYYIIQYRAKTSDTNFQEVDGVATTR----------YSIGGLSPYSEYEFRVMAVNN-IGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWLWPVQDPIIKYELQYWE-------------ADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTV------SYQAVNGEDTERHEVPDIGA------DASSCVLEGLEKWTEYQV--WVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTA--------IRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMD-VALPEAQWKIEES----TEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMI-ISTTVGNTALIQWQPP--KDMVGELMGYRLRYKRLEEENYEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIG--TPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNG-RIIHYIVVY------RDINSKQNSTNRTSDTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAF----ATSFGVKAVMKTSVLLTWEVPENYKSQVPFKILYN 1049          

HSP 3 Score: 172.555 bits (436), Expect = 2.255e-41
Identity = 244/1047 (23.30%), Postives = 439/1047 (41.93%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLL-------YNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND---------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKIP-VNITCLNIGPTDAQISWEQNPESDLPAESFTLM-IADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV--------RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVR---PGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSP-IGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYE-KNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK-NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKG 3228
            +L V++E+  P  G   I + PQ + V    T    C   GNP   ++          NG  + +  + SG  L+I + + +D    + +C+  N SA  + +A  N+    + +P   PRF +    +    G ++ + C V  G P+ +  W      L   E     +  G    +      S  Y C AI+ +G ++    ++ ++  P  P  +     V       V LT  + GNP P   ++ QY    +D          T + SI  L+  +E    +   NN   G     V+ R  ++ P  P +++    +  +   + WE   E +     + +   +DL   +  L   Q  N      D+  +T  ++ L     YS++V+ F+ ++GD  PS  + ++T++  P+ P  S  A A+  T I + W  P++    I  Y + Y          W+     + HV         +  L  +  Y   + A +  G G  + P         P  PPQ  +     ++STSI + W +PP       ++ Y + Y+ ++G+     T + E   I  D +   +  L   T Y + + A T+ G G  +T + +RT   VP +P   ++V  L+ T+I + W+  +  ++   I  +++   +L++ E   + N M V +     K +  ++ YE +I  L +  +Y + + +  + G  A     +V T     VP  P  I        T  G T L   I W PP +  G +  YR+R+  +  +N              YE +  + T+      +L  G  Y F ++A N A +G E   ++ T E  P  +P+++ + G+T+ +  ++W+PP +   NG +++Y V Y     K N+T RT+ T      I+GL+ +  Y  +V+AFT  G GP S  +  RT+   P    +     + +  + +TWE+   N    V FKI Y  Q++            G +    +  +Q ++DY   + S+G
Sbjct:  123 KLTVLEENQIPH-GFPTIDMGPQLKVVERTRTTTMLCAASGNPDPEITWFKDFLPVDINGNGR-IKQLRSG-ALQIENSEESDQG--KYECVATN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNHEVMPGGSVNLTC-VAVGAPMPYVKWMTGEVELTKDEE----MPVGRNVLELTNIRQSTNYTCVAISSLG-MIEATAQVSVKALPKPPTSL----TVTETTATSVTLTWDS-GNPEPVSYYIIQYRAKTSDTNFQEVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSEPVETRTGEQAPSSPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDL---DAPLSAWQKHNT-----DDSRLT-TISSLTTGITYSLRVLGFT-SVGDGPPSDVLQVKTQQGVPAQP-SSFEAEAELDTRILLTWLWPVQ--DPIIKYELQY----------WEADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQ--DVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGED----TERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKIEESTE-YEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTT--GAVPGKPTMI------ISTTVGNTAL---IQWQPPKDMVGELMGYRLRYKRLEEEN--------------YEIREFSRTDDHHTVTDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNGRIIHYIVVYRDINSKQNSTNRTSDT---QMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSPAFATSFGVKAVMKTSVLLTWEVPE-NYKSQVPFKILYNQQSVEVQ---------GNLKRKLITRLQPDTDYSFVLMSRG 1081          
BLAST of Receptor type tyrosine protein phosphatase vs. TrEMBL
Match: A0A1S3HSZ8 (receptor-type tyrosine-protein phosphatase delta isoform X5 OS=Lingula unguis OX=7574 GN=LOC106157176 PE=4 SV=1)

HSP 1 Score: 1202.96 bits (3111), Expect = 0.000e+0
Identity = 757/2018 (37.51%), Postives = 1078/2018 (53.42%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNG-------MKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKT-AYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQW-IHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYH--RPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYS-----RNL-QHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRW-------RKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIP-KDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNIS--FWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIF-TEITSFANDDFYPCTDSSWSRLFNFEES--PAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            II +PQS+    G    FFC+  GNP+  +    NG        +  V  +P G +LRI  V+      +   C   N   E     A L V     ++P   P+  +  +    +  +   M C  EG  P +  W KD  P+D+S+PR T+  SG++      K D G YEC A N  G   S    L +R   + P++ I  P+ ++V PG  +N+TC A G+P P +RW        P+ D    +++L+L D+ + A+Y C A + +G I+   QV+VK +P  PV++    +  T  ++SW++   ++ P +S+ +           +  K I  I           + +T L  YT Y  +V+A +  +G   PS+     T E  PS+PP++V A   + +++ V+W  P   NG I  Y VYY+      NL + P   WQ    T +   I +L  N TY + V    S G GP SE   ++ R GVP QP N +        I + W  P+    ++    +       GK           + I P    Y + +L P T+Y+I + A++E G G  S  +   T+  +P  P  + V T++ T+I +RW       R G+     +   KI +  ++ I     S + H         T +   + E +I  L+   +YK  + +V   G        I KT     VP  P + R+N + +         +  + W  P N +G ++AY++ +  VG  +  E++   +L  + Y++ VT          L  G  YEF ++A NT D G +   N+ T +S P  YP++  ++  TS    +SW+PP  +  NG ++ Y++ Y+   L +    + +   +   + GL+ N +Y FQ++A+T  G GPWS    F+T   LP  P NI+  R + + I+VTW   +  N  + G++I+Y   + P +D++      + PVT   L  +  +S Y V ++++ +D R+G +S+       + P I     S    +     + + W  P T   + K+++   G      +   +   +S    R  + V         + ++ P   Y  ++   +  DG    Y      + R ++ RP+F    E   +           L+    +G +  Y++++    H      +++    LQS   P      + A+F      +G+N+   F +        Y            R    D  + YK+FLRA     E+TS           S +S  F+ +    P  + L P     ++ V ++A +I L +  +I       + RR+ KR   +P+   +  DP+            PP      H     TD     + NF+   +  HPPIP   LA++I  LK  DN KF++EYESI+PG  FTW  SNLE+NKPKNRYANVIAYDHSRV+L  L+ I GSDYINANY DGYRKQNAYIATQGPLPETF  FWRMVWE R A IVMMTKLEER R+KCDQYWP RG+E Y    ++I  L+ ++LA YT+R F L+++      G  E R+V  FQFT WPDHGVPD   PLLMF++RV++  P DSGP++ HCSAGVGRTGA+IV+D+ L +I+HE+ VD+YG V+ LRAQRNYMVQTE+QY+FI+DALLEA  CGNTE+  R+L+AH+ KL QP P        +  TGMELEFK L+     P +F +ANLP N+ KNRL+NILPYEN RVCLQPIR  DGSDYINAS+IDGYR + AYIATQGPL  T  DFWRMLW+HNS+I+VML++LREMGREKC QYWP+ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ALSIVL+RMR EG VDLFQTVR+LR QRP MVQTEDQYQFCY  ALEYL SFD +
Sbjct:   52 IIQSPQSKKAPNGGIVSFFCKASGNPAPDIKWQKNGNDLGTSKQRYLVFDMPFGSVLRIEPVRQRRDDAM-FTCTATNGVGEAASAQAQLTVYPNDMEMPRTAPKIVVQPNLKSVEKDRPASMQCATEGTPPPRIYWLKDYIPVDISDPRITVSESGTLNIMNSRKSDQGKYECVAENEAGVAYSYAANLYVRVRNVAPRFSIQPPEMLDVMPGGDINITCVAVGSPMPVVRWKLGVTDLAPVADAPLGKNVLILKDVQQSANYTCFAASDLGNIEAITQVKVKALPNPPVHLEISEVTATSVKLSWDEG--NNDPIDSYIINYKPKYKQG--VESKSISGI-------VETEHTITGLVSYTIYEFRVVAVN-NIGRGRPSEPKECTTGEQQPSTPPRNVRARPLSTSTLYVQWDEPEIPNGLILGYQVYYTLKEEGENLAERPYYTWQNMAVTDKVANIRNLSPNRTYVVCVLGRTSVGDGPPSEYVEVLTRQGVPEQPRNLQTEVRGPDQIYVTWEKPENSDDIITSYELYYQSPSRGK---------VRVTIQPPVESYLLEDLIPATVYNIHVLAKSERGTGPESPVVQATTQEFIPGRPERVRVETVNSTAIRVRWSSPAPDKRNGIIRAYVVIYGKIDISSMQLI----GSRKRH---------TISGGQVTETVITGLQPDSSYKFQVAAVTGKGDGIYSKGKIAKTL--GAVPERPRSFRVNLINEDPP------MVQLVWQRPRNIYGALQAYKLEYGKVG-SDKFETI---ALEAEQYQRTVTS---------LDRGAEYEFRLSARNTVDYGEKAVQNIKTPDSVPYGYPMNFTMSAKTSTVAQLSWKPPPADQCNGRIIMYEIEYYK-KLDDINSFSLNVSQMETEVSGLETNEVYLFQIKAYTSKGPGPWSPKYQFKTYKQLPAAPTNIKLRRTSHSTIQVTW---NAPNFPIKGYRIFYS--SFPNRDMDLWTKKTIPPVTATDLIQLT-DSCYYVRVQAQSLDGRFGNLSD-QEENCEQPPEIPQCVRSFTAVDTSSDYVVLDWDPPLT-PGVVKYKILYEG-----SQRDILVHPRSEITVRNQERVK--------ISELFPETRYTFNISAQF-LDGSLGPYVYTLAETQRGVLERPQFRKMNEDKTIGFQ--------LKSRSRIGKVDYYWVVVVPKSHFDIKEPNEFEENELQSDISPA----YIAAQF------EGNNLPDMFSLSDGNMYGNY------------RNKRLDENEEYKVFLRAVTTENEVTS-----------SDYSEPFSLKRGVPPRRSPLTPAGGGFIWIVGVVAAVILLIIFIVIVFF----VVRRKSKRKEKAPEPTKVFVDPT------------PPG---PQHP----TDPVEMRRMNFQTPAMISHPPIPVEQLAEHIDRLKAQDNLKFSQEYESIEPGQQFTWDNSNLEVNKPKNRYANVIAYDHSRVILQPLDAITGSDYINANYMDGYRKQNAYIATQGPLPETFCDFWRMVWEQRSATIVMMTKLEERSRIKCDQYWPLRGTENYGVMQVTI--LDIMDLATYTIRTFQLSRQ------GYPEKREVKQFQFTAWPDHGVPDHPTPLLMFMRRVKASTPPDSGPMITHCSAGVGRTGAFIVIDAMLERIRHERTVDIYGHVTCLRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEIPARNLYAHLQKLTQPEP-------GETVTGMELEFKRLAHTKANPSRFVSANLPVNKFKNRLVNILPYENTRVCLQPIRGVDGSDYINASYIDGYRYRGAYIATQGPLGETTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPSERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFIALSIVLERMRYEGVVDLFQTVRMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHY 1910          
BLAST of Receptor type tyrosine protein phosphatase vs. TrEMBL
Match: A0A1S3HQ62 (receptor-type tyrosine-protein phosphatase F isoform X3 OS=Lingula unguis OX=7574 GN=LOC106157176 PE=4 SV=1)

HSP 1 Score: 1151.35 bits (2977), Expect = 0.000e+0
Identity = 750/2039 (36.78%), Postives = 1075/2039 (52.72%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNG-------MKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKT-AYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQW-IHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYH--RPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNIT---YNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRIT-----------DLFTNNTYHIKVNAVNSAGPGPVSEPFPII------VRPGVPPQPHNFRGAGITSTSINLIWSPP-------QLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSPTSIAIRW-------RKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIP-KDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNIS--FWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIF-TEITSFANDDFYPCTDSSWSRLFNFEES--PAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            II +PQS+    G    FFC+  GNP+  +    NG        +  V  +P G +LRI  V+      +   C   N   E     A L V     ++P   P+  +  +    +  +   M C  EG  P +  W KD  P+D+S+PR T+  SG++      K D G YEC A N  G   S    L +R   + P++ I  P+ ++V PG  +N+TC A G+P P +RW        P+ D    +++L+L D+ + A+Y C A + +G I+   QV+VK+    P N+    +  +   + W+   E ++P           ++      L + P  + W   N  +T    N+ +L P   Y V V+  + ++GD  PS+ + + T++  P  P +++         I V W  P  ++  IT Y +YY    Q P         +R  VR+T           DL     Y+I V A +  G GP S   P++        P  PPQ  +  G    +T+I + WSPP       Q+    +        + +    + T+  +++ + I       R  ++W  T Y I + A T  G G ++  + VRT+  VP  P  + V T++ T+I +RW       R G+     +   KI +  ++ I     S + H         T +   + E +I  L+   +YK  + +V   G        I KT     VP  P + R+N + +         +  + W  P N +G ++AY++ +  VG  +  E++   +L  + Y++ VT          L  G  YEF ++A NT D G +   N+ T +S P  YP++  ++  TS    +SW+PP  +  NG ++ Y++ Y+   L +    + +   +   + GL+ N +Y FQ++A+T  G GPWS    F+T   LP  P NI+  R + + I+VTW   +  N  + G++I+Y   + P +D++      + PVT   L  +  +S Y V ++++ +D R+G +S+       + P I     S    +     + + W  P T   + K+++   G      +   +   +S    R  + V         + ++ P   Y  ++   +  DG    Y      + R ++ RP+F    E   +           L+    +G +  Y++++    H      +++    LQS   P      + A+F      +G+N+   F +        Y            R    D  + YK+FLRA     E+TS           S +S  F+ +    P  + L P     ++ V ++A +I L +  +I       + RR+ KR   +P+   +  DP+            PP      H     TD     + NF+   +  HPPIP   LA++I  LK  DN KF++EYESI+PG  FTW  SNLE+NKPKNRYANVIAYDHSRV+L  L+ I GSDYINANY DGYRKQNAYIATQGPLPETF  FWRMVWE R A IVMMTKLEER R+KCDQYWP RG+E Y    ++I  L+ ++LA YT+R F L+++      G  E R+V  FQFT WPDHGVPD   PLLMF++RV++  P DSGP++ HCSAGVGRTGA+IV+D+ L +I+HE+ VD+YG V+ LRAQRNYMVQTE+QY+FI+DALLEA  CGNTE+  R+L+AH+ KL QP P        +  TGMELEFK L+     P +F +ANLP N+ KNRL+NILPYEN RVCLQPIR  DGSDYINAS+IDGYR + AYIATQGPL  T  DFWRMLW+HNS+I+VML++LREMGREKC QYWP+ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ALSIVL+RMR EG VDLFQTVR+LR QRP MVQTEDQYQFCY  ALEYL SFD +
Sbjct:   52 IIQSPQSKKAPNGGIVSFFCKASGNPAPDIKWQKNGNDLGTSKQRYLVFDMPFGSVLRIEPVRQRRDDAM-FTCTATNGVGEAASAQAQLTVYPNDMEMPRTAPKIVVQPNLKSVEKDRPASMQCATEGTPPPRIYWLKDYIPVDISDPRITVSESGTLNIMNSRKSDQGKYECVAENEAGVAYSYAANLYVRVRNVAPRFSIQPPEMLDVMPGGDINITCVAVGSPMPVVRWKLGVTDLAPVADAPLGKNVLILKDVQQSANYTCFAASDLGNIEAITQVKVKEPSTPPRNVRARPLSTSTLYVQWD---EPEIPNGLILGYQVYYTLKEEGENLAERP-YYTW--QNMAVTDKVANIRNLSPNRTYVVCVLGRT-SVGDGPPSEYVEVLTRQGVPEQP-RNLQTEVRGPDQIYVTWEKPENSDDIITSYELYY----QSP---------SRGKVRVTIQPPVESYLLEDLIPATVYNIHVLAKSERGTGPES---PVVQATTQEFTPSAPPQ--DVTGEIEGATAIIIKWSPPPLNARNGQITEYKIRYVETESGQQLQEASVVTVLGEKDSVVI-------RNLKIW--TKYTIWVQAATRVGPGPNSVPIVVRTDEAVPGRPERVRVETVNSTAIRVRWSSPAPDKRNGIIRAYVVIYGKIDISSMQLI----GSRKRH---------TISGGQVTETVITGLQPDSSYKFQVAAVTGKGDGIYSKGKIAKTL--GAVPERPRSFRVNLINEDPP------MVQLVWQRPRNIYGALQAYKLEYGKVG-SDKFETI---ALEAEQYQRTVTS---------LDRGAEYEFRLSARNTVDYGEKAVQNIKTPDSVPYGYPMNFTMSAKTSTVAQLSWKPPPADQCNGRIIMYEIEYYK-KLDDINSFSLNVSQMETEVSGLETNEVYLFQIKAYTSKGPGPWSPKYQFKTYKQLPAAPTNIKLRRTSHSTIQVTW---NAPNFPIKGYRIFYS--SFPNRDMDLWTKKTIPPVTATDLIQLT-DSCYYVRVQAQSLDGRFGNLSD-QEENCEQPPEIPQCVRSFTAVDTSSDYVVLDWDPPLT-PGVVKYKILYEG-----SQRDILVHPRSEITVRNQERVK--------ISELFPETRYTFNISAQF-LDGSLGPYVYTLAETQRGVLERPQFRKMNEDKTIGFQ--------LKSRSRIGKVDYYWVVVVPKSHFDIKEPNEFEENELQSDISPA----YIAAQF------EGNNLPDMFSLSDGNMYGNY------------RNKRLDENEEYKVFLRAVTTENEVTS-----------SDYSEPFSLKRGVPPRRSPLTPAGGGFIWIVGVVAAVILLIIFIVIVFF----VVRRKSKRKEKAPEPTKVFVDPT------------PPG---PQHP----TDPVEMRRMNFQTPAMISHPPIPVEQLAEHIDRLKAQDNLKFSQEYESIEPGQQFTWDNSNLEVNKPKNRYANVIAYDHSRVILQPLDAITGSDYINANYMDGYRKQNAYIATQGPLPETFCDFWRMVWEQRSATIVMMTKLEERSRIKCDQYWPLRGTENYGVMQVTI--LDIMDLATYTIRTFQLSRQ------GYPEKREVKQFQFTAWPDHGVPDHPTPLLMFMRRVKASTPPDSGPMITHCSAGVGRTGAFIVIDAMLERIRHERTVDIYGHVTCLRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEIPARNLYAHLQKLTQPEP-------GETVTGMELEFKRLAHTKANPSRFVSANLPVNKFKNRLVNILPYENTRVCLQPIRGVDGSDYINASYIDGYRYRGAYIATQGPLGETTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPSERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFIALSIVLERMRYEGVVDLFQTVRMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHY 1917          

HSP 2 Score: 109.768 bits (273), Expect = 6.812e-20
Identity = 212/947 (22.39%), Postives = 378/947 (39.92%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV--------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDV--GQNMKMNCDVEGGLPIKFNWFK----DNAPLDLSEPRRTMLRSGSIFFDRLLK--EDSGIYECRAINPVGSILSI-KMKLEIRNTPITPQWIHRPQDVEVRP---------------------GHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYIC----RANNSMGVIQHAVQVRVKK-IPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPI--EANGKITDYNVYYSRNLQHPINQWQKSETT-----RQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGK----HIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNV-RTENRVPNSPIGIDVRTLS--PTSIAIRWRKGMDNEESISSFKIKVIKLKS--IETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPP--INSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIG-LEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTST 2859
            +L V    +   + A KI+V P  ++V     A   C  +G P   +  L    K Y+        I +     L I + + +D    + +C+  N    E   AY    +    + N  PRF  I+   + DV  G ++ + C V  G P+    +K    D AP+  +   + +L         +LK  + S  Y C A + +G+I +I ++K++  +TP        P++V  RP                     G+ V  T   +G    +  + T  +  + D      +  + +++   +Y+     R +   G     V+V  ++ +P+ P N+     GP    ++WE+   SD    S+ L     S     + ++        PP     +Y + DL P T Y++ V+A S+  G    S  +   T+E  PS+PPQ V    +  T+I +KW+PP     NG+IT+Y + Y         Q Q++        +  V I +L     Y I V A    GPGP S P  +     VP +P   R   + ST+I + WS    P+       +  Y VI GK     +  + +++         T+  +T L P++ Y   +AA T  G G+ +   + +T   VP  P    V  ++  P  + + W++  +   ++ ++K++  K+ S   ET+    E                  Y+  +  L+ G  Y+  L +  +       + +I KT P ++    P+N         T S  T  +A ++W PP     +G I  Y I +        ++ +   SL+V   E  V+G         L   +VY F + A  +   G    K    T +  P + P +I +   +  ++ ++W  P     N  +  Y++ Y ++  ++  + T  T
Sbjct:  139 QLTVYPNDMEMPRTAPKIVVQPNLKSVEKDRPASMQCATEGTPPPRIYWL----KDYIPVDISDPRITVSESGTLNIMNSRKSDQG--KYECVAEN----EAGVAYSYAANLYVRVRNVAPRFS-IQPPEMLDVMPGGDINITC-VAVGSPMPVVRWKLGVTDLAPVADAPLGKNVL---------ILKDVQQSANYTCFAASDLGNIEAITQVKVKEPSTP--------PRNVRARPLSTSTLYVQWDEPEIPNGLILGYQVYYTLKEEGENLAERPYYTWQNMAVTD-----KVANIRNLSPNRTYVVCVLGRTSVGDGPPSEYVEVLTRQGVPEQPRNLQTEVRGPDQIYVTWEKPENSDDIITSYELYYQSPSRGKVRVTIQ--------PPVE---SYLLEDLIPATVYNIHVLAKSER-GTGPESPVVQATTQEFTPSAPPQDVTGEIEGATAIIIKWSPPPLNARNGQITEYKIRYVETESG--QQLQEASVVTVLGEKDSVVIRNLKIWTKYTIWVQAATRVGPGPNSVPIVVRTDEAVPGRPERVRVETVNSTAIRVRWSS---PAPDKRNGIIRAYVVIYGKIDISSMQLIGSRKRHTISGGQVTETVITGLQPDSSYKFQVAAVTGKGDGIYSKGKIAKTLGAVPERPRSFRVNLINEDPPMVQLVWQRPRNIYGALQAYKLEYGKVGSDKFETIALEAEQ-----------------YQRTVTSLDRGAEYEFRLSARNTVDYGEKAVQNI-KT-PDSVPYGYPMNF--------TMSAKTSTVAQLSWKPPPADQCNGRIIMYEIEY-----YKKLDDINSFSLNVSQMETEVSG---------LETNEVYLFQIKAYTSKGPGPWSPKYQFKTYKQLPAA-PTNIKLRRTSHSTIQVTWNAP-----NFPIKGYRIFYSSFPNRDMDLWTKKT 987          
BLAST of Receptor type tyrosine protein phosphatase vs. TrEMBL
Match: A0A2T7NQE6 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_16668 PE=4 SV=1)

HSP 1 Score: 1079.7 bits (2791), Expect = 0.000e+0
Identity = 738/2085 (35.40%), Postives = 1077/2085 (51.65%), Query Frame = 1
Query:  244 GAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRI-----------DCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTA-----------KGNPPPQLRWLTQY---HRPINDLTDKESIL----LLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDL---PAESFTLMIA--DLSIDNTVL-GLKQIPNIHPWPP---------DNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRIT-----------DLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQP-HNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKE---------EEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIY-----EYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAY--FTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSM-EIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLII----EESIHTQKTNFS--KYSFESLQSASKPISYSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFAND-----DFYPCTDSSWSRLFNFEESPAINKL--LPKKQ-------TDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            G  +I++ P+ ++V  G + I  C+  G P   +  L    K YV P+     L  P ++L +   ++I           +C+  N    E   AY         +    PRF ++ +      G ++ + C V  G P+    ++  A  DL++     +  G    +     +S  Y C A + +G+I  +   +                 VE  PG    LT +             G+  P   ++ Q+   H    D T+K +I+     +T++     Y  R          AV    +  P  P+ +T   + P          P  ++    A S T++++  +  I N ++ G K    + P  P          N N    ++ L P   Y++ ++A+S ++G    S  I + T +  P  P  +++A A +   I VKW  P EA+  I  Y +YY  N  H          TRQ+VR +           DL  +  YHI+V+A +S G GP +    +     VP  P  +  G  I    I + W PP             +   ++G  I  + N+          + +      +       W  T Y I + A T  G G  S  + V+T+  VP  P  + V  ++ T I + W +  +    I  +++  I++       NSN+     + +P + +   D +     E +I  L+    Y I +      G        I+ T+    VP+PP N+ +N +++   S        + W  P +++G++  Y+I   + GPQ   E  + + +S  VY       +Y T    L  G  YEF V+A N  D G      + T + AP   P +   TG+T  SV ++W  P     NG +V YQ+ Y      +    +  T T   +  I GL+ +  Y F+++A+T  G GPWS+ ++FRT   +P PP N++  R +   I+VTW+     N  V G+KIYY +   P  +     ++ GP T+  +G ++ ++ Y V +++K +D R+G +S   T  + E  V RD  V +     ++ ++  + W  P     ++ + +  +G  +Y +E G+V++      P+EV    +   + +  K++ P M ++ ++  +++ DGE+   G   + +  TL+  P +V  P +  V     +I L++ R +E  G I  Y++++      S++   ++F+     ++++    KP S  P + A F            F++G      +Y        + + RP+  D    Y++FLRA         ++D     D    + SS  R  +   S    K+  LP+ Q        D+    +     G  +I  I  A+   M RR+     N  + ++M  +P  K  +    V  PP  V          D     + +++   +  HPPIP   L ++I  LK  DN KF++EYESI+PG  FTW  SNLE+NKPKNRYANVIAYDHSRV+L  ++ +PGSDYINANY DGYRKQNAYIATQGPLPETF  FWRMVWE R A +VMMTKLEER R+KCDQYWP+RG+E Y    + +  +E  ELA YT+R F L++       G  E R+V  FQFT WPDHGVPD   PLLMF++RV+   P D+G ++VHCSAGVGRTGA+IV+D+ L +I+HEK VD+YG V+ LRAQRNYMVQTE+QY+FI+DALLEA  CGNTEV  R+L AH+ KL QP P        +  TGMELEFK L+ +   P +F +ANLP N+ KNRL+NILPYE+ RVCLQPIR  DGSDYINASFIDGYR +KAY+ATQGPLA T  DFWRMLW+HNS+I+VML++LREMGREKC QYWP+ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQ+QFCY  ALEYL SFD +
Sbjct:  119 GYPRILLHPKLKSVEKGLSTIMQCEAAGEPDPTIMWL----KDYV-PVD----LSDPRIQLLESGYLQIHNSQESDEATYECLAEN----ELGVAYSYPAMMYVKVRRVPPRFSILPEDQNVMPGSDVNLTC-VAVGSPMPLVKWRQGA-YDLTDEDNVPV--GKNVLELKDVRESKNYTCEASSDLGNIEHVVQVI-----------------VEALPGSPTRLTASEVTASSVKLSWDSGSREPVYSYIIQFKPKHDAAADYTEKRNIVHNVYTVTNLKAFTDYQFRVV--------AVSNIARSTPSAPLEVTTGELAPG--------TPPRNIRARAASSTTIVVSWDEPEIPNGIIQGYKVFYTLKPEDPVFFWEQQEVKNDNRLTTISGLEPNQTYTISILAYS-SIGPGPMSHPIQVLTTQGVPYQP-LNLHAEAISPNEIVVKWDAPQEAD-SIISYELYY--NDSH----------TRQNVRFSIHPPVSSYRLEDLTPDTVYHIQVSAKSSRGEGPRTPTVQVKTHAFVPEAPPQDVSGRPIDEHQIKVSWKPP---------IANKQNGALAGYKIYFVANEAGKTDNDAIMKNVDSSSLSSILDGLSTW--TEYKIWVVAYTAVGDGPASPPIVVQTDEDVPGEPRKVKVEAINSTGIFVEWTEPKEPNGKIRGYQVYYIEV-------NSND-----EPIPGRAERYHDTFSGSTKEAVITGLDPDTRYLIQVAGYTRKGDGMRSNPRIITTK--GAVPTPPRNLHVNLIQEDPPS------VKVTWQRPRDTYGSLENYKI---IWGPQG--ERYEEKIMSADVY-------SYVT--STLDRGTTYEFRVSAKNNVDYGERAVDTIRTPDGAPSGAPQNFTATGLTETSVRLTWDLPARNLRNGDIVMYQITYHKLADAINEEDLNITDT---FVDIVGLEMDTDYIFKIKAYTSRGAGPWSNRLHFRTFGRMPPPPQNVKVRRTSSTSIEVTWD---EPNFPVAGYKIYYNMFATPA-MYVWQQMETGPYTVADIGGLEPHTVYAVRVQAKSVDGRFGNLSETVTTDVKE--VQRDNVVQNFHVTQRLTNLVRLSW-SPSEKPGVNIYLLKYSGVKTY-RENGQVKQINQD--PQEVRIPGQMTSWTV--KNLQPKMKFEFNISVIFQ-DGET---GPDVHITTETLINAPPYVEAPVVSAVE--GGTIVLKLERASEKNGPISHYHIVVVPLKSGSVNKMPSDFTMDDLIYDNM-GMDKPAS-RPYIAARFEAQALPP----QFYLGNG---QEY-------GAFVNRPL--DKDDKYRVFLRAYSVDPRLYKSSDYSDEIDISGVSGSSNVRTTSTAGSNGSGKVSTLPRGQEVQDFDEKDMLLTIVAPTCSGAVLIICICAAITYLMMRRK-----NKSKSVMM--EPEAKALM----VDVPPYLV----------DPVEMRRQHYQTPAMISHPPIPIERLGEHIEMLKAADNLKFSQEYESIEPGQQFTWDNSNLEVNKPKNRYANVIAYDHSRVILQPIDGVPGSDYINANYMDGYRKQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTKLEERSRIKCDQYWPSRGAETYGL--MHVQLVEVTELATYTIRTFHLSRY------GCPEKREVRQFQFTAWPDHGVPDHPTPLLMFMRRVKVSNPPDTGSMIVHCSAGVGRTGAFIVIDAMLERIKHEKTVDIYGHVTCLRAQRNYMVQTEDQYIFIHDALLEAVQCGNTEVPARNLAAHIQKLTQPEP-------GETVTGMELEFKRLANVKASPNRFISANLPVNKFKNRLVNILPYESTRVCLQPIRGVDGSDYINASFIDGYRYKKAYVATQGPLAETTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPSERSARYQYFVVDPMTEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKMLRTQRPAMVQTEDQFQFCYRAALEYLGSFDHY 2017          

HSP 2 Score: 305.064 bits (780), Expect = 1.872e-79
Identity = 271/1031 (26.29%), Postives = 459/1031 (44.52%), Query Frame = 1
Query:  238 RKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNG-------MKKYVIPIPSGLMLRIPDVKLT--DGKPVRIDCIVRNPSAEEKKTAYLNV---TDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKE------SILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIA---DLSIDNTVLGLKQIPNIHPWPPDNKNITYN---VTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQH--VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSH--SVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEG-LQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPD-PPINIEASRINENQIKVTWELSHTN--NIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKS 3222
            R G  KI +AP+SQ V    TA FFC+  GNP+  ++    G        +  ++ +P   +LRI  V+    DG      C+  N   E +  A L V    + + + P+G+PR  L       + G +  M C+  G       W KD  P+DLS+PR  +L SG +      + D   YEC A N +G   S    + ++   + P++   P+D  V PG  VNLTC A G+P P ++W    +    DLTD++      ++L L D+ E  +Y C A++ +G I+H VQV V+ +P  P  +T   +  +  ++SW+    S  P  S+ +      D + D T               + +NI +N   VT+L+ +T Y  +V+A S  +  S PS  + + T EL P +PP+++ A A + T+I V W  P   NG I  Y V+Y+   + P+  W++ E    +    I+ L  N TY I + A +S GPGP+S P  ++   GVP QP N     I+   I + W  PQ          +      +  H    T +     I P  + YR+ +L P+T+YHI ++A++  G G  + T+ V+T   VP + P  +  R +    I + W+  + N++  +++ +KI  +  ++ +T +++   +V   S+ +     S   EY I        + +   +VG    S P +    +  PG      P  +++  +     +G+      + W  P   +G IR Y++ +  V   +  E +  R+   + Y    +G+        L     Y   VA       G+     + T + A  + P ++ +  I     SV ++WQ P   +  G L NY++ +   G +        + ++Y+ +   L     Y F+V A   V  G  + D   RT    P   P N  A+ + E  +++TW+L   N  N  +V ++I Y       + E  N  D    T V +  ++ ++DY   IK+
Sbjct:   11 RGGPPKITLAPKSQKVAEDGTASFFCKASGNPAPSIAWEKRGKTIVSRRTRYEIVDVPHMSVLRIKPVRAAREDG---LYTCVATNSLGEARANATLYVYKKDEVNGEFPSGYPRILLHPKLKSVEKGLSTIMQCEAAGEPDPTIMWLKDYVPVDLSDPRIQLLESGYLQIHNSQESDEATYECLAENELGVAYSYPAMMYVKVRRVPPRFSILPEDQNVMPGSDVNLTCVAVGSPMPLVKWRQGAY----DLTDEDNVPVGKNVLELKDVRESKNYTCEASSDLGNIEHVVQVIVEALPGSPTRLTASEVTASSVKLSWDSG--SREPVYSYIIQFKPKHDAAADYT---------------EKRNIVHNVYTVTNLKAFTDYQFRVVAVS-NIARSTPSAPLEVTTGELAPGTPPRNIRARAASSTTIVVSWDEPEIPNGIIQGYKVFYTLKPEDPVFFWEQQEVKNDNRLTTISGLEPNQTYTISILAYSSIGPGPMSHPIQVLTTQGVPYQPLNLHAEAISPNEIVVKWDAPQ-----EADSIISYELYYNDSH----TRQNVRFSIHPPVSSYRLEDLTPDTVYHIQVSAKSSRGEGPRTPTVQVKTHAFVPEAPPQDVSGRPIDEHQIKVSWKPPIANKQNGALAGYKIYFVANEAGKTDNDAIMKNVDSSSLSSILDGLSTWTEYKI--------WVVAYTAVGDGPASPPIVVQTDEDVPGE-----PRKVKVEAI---NSTGIF-----VEWTEPKEPNGKIRGYQVYYIEVNSND--EPIPGRA---ERYHDTFSGSTKEAVITGLDPDTRYLIQVAGYTRKGDGMRSNPRIITTKGAVPTPPRNLHVNLIQEDPPSVKVTWQRP--RDTYGSLENYKIIWGPQGERYE--EKIMSADVYSYVTSTLDRGTTYEFRVSAKNNVDYGERAVDT-IRTPDGAPSGAPQNFTATGLTETSVRLTWDLPARNLRNGDIVMYQITYHKLADAINEEDLNITD----TFVDIVGLEMDTDYIFKIKA 972          
BLAST of Receptor type tyrosine protein phosphatase vs. TrEMBL
Match: A0A1S3HRJ8 (tyrosine-protein phosphatase Lar isoform X2 OS=Lingula unguis OX=7574 GN=LOC106157176 PE=4 SV=1)

HSP 1 Score: 1034.63 bits (2674), Expect = 0.000e+0
Identity = 653/1682 (38.82%), Postives = 918/1682 (54.58%), Query Frame = 1
Query: 1285 NVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRIT-----------DLFTNNTYHIKVNAVNSAGPGPVSEPFPII------VRPGVPPQPHNFRGAGITSTSINLIWSPP-------QLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSPTSIAIRW-------RKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIP-KDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNIS--FWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIF-TEITSFANDDFYPCTDSSWSRLFNFEES--PAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            N+ +L P   Y V V+  + ++GD  PS+ + + T++  P  P +++         I V W  P  ++  IT Y +YY    Q P         +R  VR+T           DL     Y+I V A +  G GP S   P++        P  PPQ  +  G    +T+I + WSPP       Q+    +        + +    + T+  +++ + I       R  ++W  T Y I + A T  G G ++  + VRT+  VP  P  + V T++ T+I +RW       R G+     +   KI +  ++ I     S + H         T +   + E +I  L+   +YK  + +V   G        I KT     VP  P + R+N + +         +  + W  P N +G ++AY++ +  VG  +  E++   +L  + Y++ VT          L  G  YEF ++A NT D G +   N+ T +S P  YP++  ++  TS    +SW+PP  +  NG ++ Y++ Y+   L +    + +   +   + GL+ N +Y FQ++A+T  G GPWS    F+T   LP  P NI+  R + + I+VTW   +  N  + G++I+Y   + P +D++      + PVT   L  +  +S Y V ++++ +D R+G +S+       + P I     S    +     + + W  P T   + K+++   G      +   +   +S    R  + V         + ++ P   Y  ++   +  DG    Y      + R ++ RP+F    E   +           L+    +G +  Y++++    H      +++    LQS   P      + A+F      +G+N+   F +        Y            R    D  + YK+FLRA     E+TS           S +S  F+ +    P  + L P     ++ V ++A +I L +  +I       + RR+ KR   +P+   +  DP+            PP      H     TD     + NF+   +  HPPIP   LA++I  LK  DN KF++EYESI+PG  FTW  SNLE+NKPKNRYANVIAYDHSRV+L  L+ I GSDYINANY DGYRKQNAYIATQGPLPETF  FWRMVWE R A IVMMTKLEER R+KCDQYWP RG+E Y    ++I  L+ ++LA YT+R F L+++      G  E R+V  FQFT WPDHGVPD   PLLMF++RV++  P DSGP++ HCSAGVGRTGA+IV+D+ L +I+HE+ VD+YG V+ LRAQRNYMVQTE+QY+FI+DALLEA  CGNTE+  R+L+AH+ KL QP P        +  TGMELEFK L+     P +F +ANLP N+ KNRL+NILPYEN RVCLQPIR  DGSDYINAS+IDGYR + AYIATQGPL  T  DFWRMLW+HNS+I+VML++LREMGREKC QYWP+ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ALSIVL+RMR EG VDLFQTVR+LR QRP MVQTEDQYQFCY  ALEYL SFD +
Sbjct:  482 NIRNLSPNRTYVVCVLGRT-SVGDGPPSEYVEVLTRQGVPEQP-RNLQTEVRGPDQIYVTWEKPENSDDIITSYELYY----QSP---------SRGKVRVTIQPPVESYLLEDLIPATVYNIHVLAKSERGTGPES---PVVQATTQEFTPSAPPQ--DVTGEIEGATAIIIKWSPPPLNARNGQITEYKIRYVETESGQQLQEASVVTVLGEKDSVVI-------RNLKIW--TKYTIWVQAATRVGPGPNSVPIVVRTDEAVPGRPERVRVETVNSTAIRVRWSSPAPDKRNGIIRAYVVIYGKIDISSMQLI----GSRKRH---------TISGGQVTETVITGLQPDSSYKFQVAAVTGKGDGIYSKGKIAKTL--GAVPERPRSFRVNLINEDPP------MVQLVWQRPRNIYGALQAYKLEYGKVG-SDKFETI---ALEAEQYQRTVTS---------LDRGAEYEFRLSARNTVDYGEKAVQNIKTPDSVPYGYPMNFTMSAKTSTVAQLSWKPPPADQCNGRIIMYEIEYYK-KLDDINSFSLNVSQMETEVSGLETNEVYLFQIKAYTSKGPGPWSPKYQFKTYKQLPAAPTNIKLRRTSHSTIQVTW---NAPNFPIKGYRIFYS--SFPNRDMDLWTKKTIPPVTATDLIQLT-DSCYYVRVQAQSLDGRFGNLSD-QEENCEQPPEIPQCVRSFTAVDTSSDYVVLDWDPPLT-PGVVKYKILYEG-----SQRDILVHPRSEITVRNQERVK--------ISELFPETRYTFNISAQF-LDGSLGPYVYTLAETQRGVLERPQFRKMNEDKTIGFQ--------LKSRSRIGKVDYYWVVVVPKSHFDIKEPNEFEENELQSDISPA----YIAAQF------EGNNLPDMFSLSDGNMYGNY------------RNKRLDENEEYKVFLRAVTTENEVTS-----------SDYSEPFSLKRGVPPRRSPLTPAGGGFIWIVGVVAAVILLIIFIVIVFF----VVRRKSKRKEKAPEPTKVFVDPT------------PPG---PQHP----TDPVEMRRMNFQTPAMISHPPIPVEQLAEHIDRLKAQDNLKFSQEYESIEPGQQFTWDNSNLEVNKPKNRYANVIAYDHSRVILQPLDAITGSDYINANYMDGYRKQNAYIATQGPLPETFCDFWRMVWEQRSATIVMMTKLEERSRIKCDQYWPLRGTENYGVMQVTI--LDIMDLATYTIRTFQLSRQ------GYPEKREVKQFQFTAWPDHGVPDHPTPLLMFMRRVKASTPPDSGPMITHCSAGVGRTGAFIVIDAMLERIRHERTVDIYGHVTCLRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEIPARNLYAHLQKLTQPEP-------GETVTGMELEFKRLAHTKANPSRFVSANLPVNKFKNRLVNILPYENTRVCLQPIRGVDGSDYINASYIDGYRYRGAYIATQGPLGETTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPSERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFIALSIVLERMRYEGVVDLFQTVRMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHY 1997          

HSP 2 Score: 242.662 bits (618), Expect = 2.281e-60
Identity = 260/1022 (25.44%), Postives = 428/1022 (41.88%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNG-------MKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKT-AYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQW-IHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYH--RPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYS-----RNL-QHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNL--VGPQNLIESLKRRSLS-VKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHS--VNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLP-DPPINIEASRINENQIKVTWELSHTN--NIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVT-LGNVQYNSDYQVGIKS 3222
            II +PQS+    G    FFC+  GNP+  +    NG        +  V  +P G +LRI  V+      +   C   N   E     A L V     ++P   P+  +  +    +  +   M C  EG  P +  W KD  P+D+S+PR T+  SG++      K D G YEC A N  G   S    L +R   + P++ I  P+ ++V PG  +N+TC A G+P P +RW        P+ D    +++L+L D+ + A+Y C A + +G I+   QV+VK +P  PV++    +  T  ++SW++   ++ P +S+ +           +  K I  I           + +T L  YT Y  +V+A +  +G   PS+     T E  PS+PP++V A   + +++ V+W  P   NG I  Y VYY+      NL + P   WQ    T +   I +L  N TY + V    S G GP SE   ++ R GVP QP N +        I + W  P+    ++    +       GK           + I P    Y + +L P T+Y+I + A++E G G  S  +   T+   P++ P  +       T+I I+W     N  +  I+ +KI+ ++ +S +         +Q  SV      +  +   +I +L+    Y I + +   VG    S P +      R    VP  P  +R+  +        T +    +   P   +G IRAY + +    +    LI S KR ++S  +V E  +TG         L     Y+F VAA+     G+  K  ++    A    P S  +  I      V + WQ P   N  G L  Y++ Y   G                 +  L     Y F++ A   V  G  +   N +T   +P   P+N   S       +++W+    +  N +++ ++I Y      K ++  N+  +    M T +  ++ N  Y   IK+
Sbjct:   36 IIQSPQSKKAPNGGIVSFFCKASGNPAPDIKWQKNGNDLGTSKQRYLVFDMPFGSVLRIEPVRQRRDDAM-FTCTATNGVGEAASAQAQLTVYPNDMEMPRTAPKIVVQPNLKSVEKDRPASMQCATEGTPPPRIYWLKDYIPVDISDPRITVSESGTLNIMNSRKSDQGKYECVAENEAGVAYSYAANLYVRVRNVAPRFSIQPPEMLDVMPGGDINITCVAVGSPMPVVRWKLGVTDLAPVADAPLGKNVLILKDVQQSANYTCFAASDLGNIEAITQVKVKALPNPPVHLEISEVTATSVKLSWDEG--NNDPIDSYIINYKPKYKQG--VESKSISGI-------VETEHTITGLVSYTIYEFRVVAVN-NIGRGRPSEPKECTTGEQQPSTPPRNVRARPLSTSTLYVQWDEPEIPNGLILGYQVYYTLKEEGENLAERPYYTWQNMAVTDKVANIRNLSPNRTYVVCVLGRTSVGDGPPSEYVEVLTRQGVPEQPRNLQTEVRGPDQIYVTWEKPENSDDIITSYELYYQSPSRGKV---------RVTIQPPVESYLLEDLIPATVYNIHVLAKSERGTGPESPVVQATTQEFTPSAPPQDVTGEIEGATAIIIKWSPPPLNARNGQITEYKIRYVETESGQ--------QLQEASVVTVLGEKDSV---VIRNLKIWTKYTIWVQAATRVGPGPNSVPIV-----VRTDEAVPGRPERVRVETVNS------TAIRVRWSSPAPDKRNGIIRAYVVIYGKIDISSMQLIGSRKRHTISGGQVTETVITG---------LQPDSSYKFQVAAVTGKGDGIYSKGKIAKTLGAVPERPRSFRVNLINEDPPMVQLVWQRP--RNIYGALQAYKLEYGKVGSDKFETIALEAEQYQRTVTSLDRGAEYEFRLSARNTVDYGEKAVQ-NIKTPDSVPYGYPMNFTMSAKTSTVAQLSWKPPPADQCNGRIIMYEIEYY-----KKLDDINSFSLNVSQMETEVSGLETNEVYLFQIKA 996          
BLAST of Receptor type tyrosine protein phosphatase vs. TrEMBL
Match: A0A1S3HQ57 (tyrosine-protein phosphatase Lar isoform X1 OS=Lingula unguis OX=7574 GN=LOC106157176 PE=4 SV=1)

HSP 1 Score: 1033.86 bits (2672), Expect = 0.000e+0
Identity = 653/1682 (38.82%), Postives = 918/1682 (54.58%), Query Frame = 1
Query: 1285 NVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRIT-----------DLFTNNTYHIKVNAVNSAGPGPVSEPFPII------VRPGVPPQPHNFRGAGITSTSINLIWSPP-------QLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNT-MNVRTENRVPNSPIGIDVRTLSPTSIAIRW-------RKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIP-KDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNIS--FWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIF-TEITSFANDDFYPCTDSSWSRLFNFEES--PAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            N+ +L P   Y V V+  + ++GD  PS+ + + T++  P  P +++         I V W  P  ++  IT Y +YY    Q P         +R  VR+T           DL     Y+I V A +  G GP S   P++        P  PPQ  +  G    +T+I + WSPP       Q+    +        + +    + T+  +++ + I       R  ++W  T Y I + A T  G G ++  + VRT+  VP  P  + V T++ T+I +RW       R G+     +   KI +  ++ I     S + H         T +   + E +I  L+   +YK  + +V   G        I KT     VP  P + R+N + +         +  + W  P N +G ++AY++ +  VG  +  E++   +L  + Y++ VT          L  G  YEF ++A NT D G +   N+ T +S P  YP++  ++  TS    +SW+PP  +  NG ++ Y++ Y+   L +    + +   +   + GL+ N +Y FQ++A+T  G GPWS    F+T   LP  P NI+  R + + I+VTW   +  N  + G++I+Y   + P +D++      + PVT   L  +  +S Y V ++++ +D R+G +S+       + P I     S    +     + + W  P T   + K+++   G      +   +   +S    R  + V         + ++ P   Y  ++   +  DG    Y      + R ++ RP+F    E   +           L+    +G +  Y++++    H      +++    LQS   P      + A+F      +G+N+   F +        Y            R    D  + YK+FLRA     E+TS           S +S  F+ +    P  + L P     ++ V ++A +I L +  +I       + RR+ KR   +P+   +  DP+            PP      H     TD     + NF+   +  HPPIP   LA++I  LK  DN KF++EYESI+PG  FTW  SNLE+NKPKNRYANVIAYDHSRV+L  L+ I GSDYINANY DGYRKQNAYIATQGPLPETF  FWRMVWE R A IVMMTKLEER R+KCDQYWP RG+E Y    ++I  L+ ++LA YT+R F L+++      G  E R+V  FQFT WPDHGVPD   PLLMF++RV++  P DSGP++ HCSAGVGRTGA+IV+D+ L +I+HE+ VD+YG V+ LRAQRNYMVQTE+QY+FI+DALLEA  CGNTE+  R+L+AH+ KL QP P        +  TGMELEFK L+     P +F +ANLP N+ KNRL+NILPYEN RVCLQPIR  DGSDYINAS+IDGYR + AYIATQGPL  T  DFWRMLW+HNS+I+VML++LREMGREKC QYWP+ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ALSIVL+RMR EG VDLFQTVR+LR QRP MVQTEDQYQFCY  ALEYL SFD +
Sbjct:  498 NIRNLSPNRTYVVCVLGRT-SVGDGPPSEYVEVLTRQGVPEQP-RNLQTEVRGPDQIYVTWEKPENSDDIITSYELYY----QSP---------SRGKVRVTIQPPVESYLLEDLIPATVYNIHVLAKSERGTGPES---PVVQATTQEFTPSAPPQ--DVTGEIEGATAIIIKWSPPPLNARNGQITEYKIRYVETESGQQLQEASVVTVLGEKDSVVI-------RNLKIW--TKYTIWVQAATRVGPGPNSVPIVVRTDEAVPGRPERVRVETVNSTAIRVRWSSPAPDKRNGIIRAYVVIYGKIDISSMQLI----GSRKRH---------TISGGQVTETVITGLQPDSSYKFQVAAVTGKGDGIYSKGKIAKTL--GAVPERPRSFRVNLINEDPP------MVQLVWQRPRNIYGALQAYKLEYGKVG-SDKFETI---ALEAEQYQRTVTS---------LDRGAEYEFRLSARNTVDYGEKAVQNIKTPDSVPYGYPMNFTMSAKTSTVAQLSWKPPPADQCNGRIIMYEIEYYK-KLDDINSFSLNVSQMETEVSGLETNEVYLFQIKAYTSKGPGPWSPKYQFKTYKQLPAAPTNIKLRRTSHSTIQVTW---NAPNFPIKGYRIFYS--SFPNRDMDLWTKKTIPPVTATDLIQLT-DSCYYVRVQAQSLDGRFGNLSD-QEENCEQPPEIPQCVRSFTAVDTSSDYVVLDWDPPLT-PGVVKYKILYEG-----SQRDILVHPRSEITVRNQERVK--------ISELFPETRYTFNISAQF-LDGSLGPYVYTLAETQRGVLERPQFRKMNEDKTIGFQ--------LKSRSRIGKVDYYWVVVVPKSHFDIKEPNEFEENELQSDISPA----YIAAQF------EGNNLPDMFSLSDGNMYGNY------------RNKRLDENEEYKVFLRAVTTENEVTS-----------SDYSEPFSLKRGVPPRRSPLTPAGGGFIWIVGVVAAVILLIIFIVIVFF----VVRRKSKRKEKAPEPTKVFVDPT------------PPG---PQHP----TDPVEMRRMNFQTPAMISHPPIPVEQLAEHIDRLKAQDNLKFSQEYESIEPGQQFTWDNSNLEVNKPKNRYANVIAYDHSRVILQPLDAITGSDYINANYMDGYRKQNAYIATQGPLPETFCDFWRMVWEQRSATIVMMTKLEERSRIKCDQYWPLRGTENYGVMQVTI--LDIMDLATYTIRTFQLSRQ------GYPEKREVKQFQFTAWPDHGVPDHPTPLLMFMRRVKASTPPDSGPMITHCSAGVGRTGAFIVIDAMLERIRHERTVDIYGHVTCLRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEIPARNLYAHLQKLTQPEP-------GETVTGMELEFKRLAHTKANPSRFVSANLPVNKFKNRLVNILPYENTRVCLQPIRGVDGSDYINASYIDGYRYRGAYIATQGPLGETTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPSERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFIALSIVLERMRYEGVVDLFQTVRMLRTQRPAMVQTEDQYQFCYRAALEYLGSFDHY 2013          

HSP 2 Score: 243.047 bits (619), Expect = 2.284e-60
Identity = 260/1022 (25.44%), Postives = 428/1022 (41.88%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNG-------MKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKT-AYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQW-IHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYH--RPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYS-----RNL-QHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNL--VGPQNLIESLKRRSLS-VKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHS--VNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLP-DPPINIEASRINENQIKVTWELSHTN--NIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVT-LGNVQYNSDYQVGIKS 3222
            II +PQS+    G    FFC+  GNP+  +    NG        +  V  +P G +LRI  V+      +   C   N   E     A L V     ++P   P+  +  +    +  +   M C  EG  P +  W KD  P+D+S+PR T+  SG++      K D G YEC A N  G   S    L +R   + P++ I  P+ ++V PG  +N+TC A G+P P +RW        P+ D    +++L+L D+ + A+Y C A + +G I+   QV+VK +P  PV++    +  T  ++SW++   ++ P +S+ +           +  K I  I           + +T L  YT Y  +V+A +  +G   PS+     T E  PS+PP++V A   + +++ V+W  P   NG I  Y VYY+      NL + P   WQ    T +   I +L  N TY + V    S G GP SE   ++ R GVP QP N +        I + W  P+    ++    +       GK           + I P    Y + +L P T+Y+I + A++E G G  S  +   T+   P++ P  +       T+I I+W     N  +  I+ +KI+ ++ +S +         +Q  SV      +  +   +I +L+    Y I + +   VG    S P +      R    VP  P  +R+  +        T +    +   P   +G IRAY + +    +    LI S KR ++S  +V E  +TG         L     Y+F VAA+     G+  K  ++    A    P S  +  I      V + WQ P   N  G L  Y++ Y   G                 +  L     Y F++ A   V  G  +   N +T   +P   P+N   S       +++W+    +  N +++ ++I Y      K ++  N+  +    M T +  ++ N  Y   IK+
Sbjct:   52 IIQSPQSKKAPNGGIVSFFCKASGNPAPDIKWQKNGNDLGTSKQRYLVFDMPFGSVLRIEPVRQRRDDAM-FTCTATNGVGEAASAQAQLTVYPNDMEMPRTAPKIVVQPNLKSVEKDRPASMQCATEGTPPPRIYWLKDYIPVDISDPRITVSESGTLNIMNSRKSDQGKYECVAENEAGVAYSYAANLYVRVRNVAPRFSIQPPEMLDVMPGGDINITCVAVGSPMPVVRWKLGVTDLAPVADAPLGKNVLILKDVQQSANYTCFAASDLGNIEAITQVKVKALPNPPVHLEISEVTATSVKLSWDEG--NNDPIDSYIINYKPKYKQG--VESKSISGI-------VETEHTITGLVSYTIYEFRVVAVN-NIGRGRPSEPKECTTGEQQPSTPPRNVRARPLSTSTLYVQWDEPEIPNGLILGYQVYYTLKEEGENLAERPYYTWQNMAVTDKVANIRNLSPNRTYVVCVLGRTSVGDGPPSEYVEVLTRQGVPEQPRNLQTEVRGPDQIYVTWEKPENSDDIITSYELYYQSPSRGKV---------RVTIQPPVESYLLEDLIPATVYNIHVLAKSERGTGPESPVVQATTQEFTPSAPPQDVTGEIEGATAIIIKWSPPPLNARNGQITEYKIRYVETESGQ--------QLQEASVVTVLGEKDSV---VIRNLKIWTKYTIWVQAATRVGPGPNSVPIV-----VRTDEAVPGRPERVRVETVNS------TAIRVRWSSPAPDKRNGIIRAYVVIYGKIDISSMQLIGSRKRHTISGGQVTETVITG---------LQPDSSYKFQVAAVTGKGDGIYSKGKIAKTLGAVPERPRSFRVNLINEDPPMVQLVWQRP--RNIYGALQAYKLEYGKVGSDKFETIALEAEQYQRTVTSLDRGAEYEFRLSARNTVDYGEKAVQ-NIKTPDSVPYGYPMNFTMSAKTSTVAQLSWKPPPADQCNGRIIMYEIEYY-----KKLDDINSFSLNVSQMETEVSGLETNEVYLFQIKA 1012          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Cavefish
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668])

HSP 1 Score: 868.611 bits (2243), Expect = 0.000e+0
Identity = 405/604 (67.05%), Postives = 476/604 (78.81%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD++  LK NDN KF++EYESIDPG  FTW  SNLE+NK KNRYANVIAYDHSRV+LS ++ IPGSDYINANY DGYRKQNAYIATQG LPETF  FWRMVWE R A IVMMTKLEER RVKCDQYWPTRG+E Y    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QYVFI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY   LEYL SFD + +
Sbjct: 1325 NFQTPGMASHPPIPIMDLADHLERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKAKNRYANVIAYDHSRVLLSAIDGIPGSDYINANYIDGYRKQNAYIATQGSLPETFGDFWRMVWEQRSANIVMMTKLEERSRVKCDQYWPTRGTETYGL--IQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLANTKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFDHYAT 1912          

HSP 2 Score: 266.929 bits (681), Expect = 3.476e-71
Identity = 276/1042 (26.49%), Postives = 452/1042 (43.38%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKL------EIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQH-VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHI--PTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIK-VIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRH-NLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKN----TTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQ----IKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIESCNT----LDVGPVTMVTLGNVQYNSDYQV---GIKSKG 3228
            K +  P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   T  L V    + LP GFP   +     V +  +   M C   G      +WFKD  P++ +    R   LRSG++  ++  + D G YEC A N  G+  S    L      E+R  P  P++   P D E+ PG  VN+TC A G+P P ++W+  ++   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P  +       T   ++W+  NPE   P   + +       +++    K+I  +           Y+V  L PY+ Y  +V+A +  +G    S+ I  +T E  PS+ P+ V     + T+  + W  P EANG+I  Y VYY+ +    +NQW+K      + + I  L  N TY+IKV A  S G GP+S    II + GVP QP +F+    + TSI L W +PPQ            +   I+G  +       KEE+       T Y + +L P T Y   LAAR+ HG+G  +N ++  T    P++ P  +   + S T+I + W+      E  +   IK  I+  + E  D +     +I  +P +        +Y++ +LE    Y++ + +    G     +  +++T     VPS PP  + +  +   +          + W  P+    HG IR Y++ +  +   + +   + +  L      +    T Y     +L     Y  +VAA  T   G   K   V+T  + P+   + +  T +   +  + W PP   N +G L  Y++    +G K+    T I      N Y   E + +   YTF++ A  KVG G    +   + +    D P     S + E+     I+V+W+   L+  N     G  I Y LQ   KDI S  +        P + V L  ++ ++ Y +      SKG
Sbjct:   30 KFLRTPNDQTGVQGGVASFICQATGDP--RPKIVWNKKGKRVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNTVGEISATTRLTVLREDQ-LPAGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTTNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRELREVRRVP--PRFSIPPTDSEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGVIEAVAQITVKALPKPPGVLVVTERTATSITLTWDSGNPE---PVSYYIIQHKSKYSEDS---YKEIDGV-------ATTRYSVGGLSPYSDYEFRVVAVNN-IGRGPASEAIEDKTAEQAPSTAPRQVRGRMLSATTAIIHWEEPEEANGQIMGYRVYYTMDPSQHVNQWEKQIVRNANFLTIQGLTPNKTYYIKVLAYTSVGDGPLSSDLQIIAKTGVPSQPMDFKAEAKSETSILLSWVAPPQ----------SGQDNQITGYELLYKRKDEKEEKRVSFESTTTYLLKDLRPFTTYSFQLAARSRHGIGAYTNEISAETPQTQPSAPPQEVTCSSPSSTNILVSWKP--PPVELQNGIIIKYTIQYAATEGEDTTTR---EISEIPPEN------VQYLLENLEKWTEYRVTVTAHTDVGPGPESLPQLIRTE--EDVPSGPPRKVEVEAVNSSS--------VKVLWRSPVPNRQHGQIRGYQVHYVRMFNGEPVGHPVIKDILIDDAQWEYDDSTEYEMVLTDLQAETTYSVTVAAYTTKGDGARSKPKLVTTMGAVPEKPRLMVSPTNM--GTALLQWHPP--PNTHGPLQGYRL---RFGRKDVEPLTVIEFPERENHYTTKE-IHKGASYTFRLSARNKVGFG----EETVKEISTSEDTPSGFPQSIVAESATTTTIQVSWQPVLLAERN-----GIIIKYALQY--KDINSPRSPSELFIAAPESTVILDGLKADTTYDIKMCAFTSKG 1001          

HSP 3 Score: 159.458 bits (402), Expect = 2.356e-38
Identity = 249/1091 (22.82%), Postives = 444/1091 (40.70%), Query Frame = 1
Query:  205 RLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM-------KKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTA---YLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEV---RPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKE---------SILLLTDITEPASYICRANN-SMGVIQHAVQVR-VKKIPKI-PVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYN-----VTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEA--NGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGP----VSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMN-VRTENRVPNSP-IGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNL--VGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGL-KNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKV 3336
            RL V++E   P  G   I + PQ + V    TA   C   GNP   +S   + +          +  + SG  L+I   + +D    + +C+  N            Y+      + +P   PRF +         G ++ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I ++          IT + + +P  V V   R    + LT  + GNP P   ++ Q+    ++ + KE         S+  L+  ++    +   NN   G    A++ +  ++ P   P  +    +  T A I WE+  E++     + +             +    +++ W    K I  N     +  L P   Y +KV+A++ ++GD   S  + I  K   PS P     A A + TSI + W  P ++  + +IT Y + Y R  +    +     TT   ++  DL    TY  ++ A +  G G     +S   P   +P  PPQ      +  +ST+I + W PP  P +L     +      +       T +E   +I P+   Y +  L   T Y +++ A T+ G G  +    +RTE  VP+ P   ++V  ++ +S+ + WR  + N +   I  +++  +++ + E V +     + I     +  + ++ YE ++ DL+    Y + + +  + G  A     +V T     VP  P   RL  +   T  G  LL     W PP N+HG ++ YR+R     V P  +IE  +R +             +Y T+  E+  G  Y F ++A N    G E    +ST E  P  +P SI     T+ ++ +SWQP L+   NGI++ Y + Y      ++ +    + P    +++GL+ +  Y  ++ AFT  G GP+S  + FRT  L      N       +  + +TWE+    N       +Y   Q++  D         G +T   + N+Q  + Y   + ++G ++  GL   ++T    ++   +   +     +G V
Sbjct:  117 RLTVLREDQLP-AGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTTNNNGRIKQLRSG-ALQIEQSEESDQG--KYECVATNNDGTRYSAPANLYVRELREVRRVP---PRFSIPPTDSEIMPGGSVNITC-VAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDV-------RQSANYTCVAMSTLGVIEAVAQ--------ITVKALPKPPGVLVVTERTATSITLTWDS-GNPEPVSYYIIQHKSKYSEDSYKEIDGVATTRYSVGGLSPYSDYEFRVVAVNNIGRGPASEAIEDKTAEQAPSTAPRQVRGRMLSATTAIIHWEEPEEANGQIMGYRVYYT----------MDPSQHVNQW---EKQIVRNANFLTIQGLTPNKTYYIKVLAYT-SVGDGPLSSDLQIIAKTGVPSQP-MDFKAEAKSETSILLSWVAPPQSGQDNQITGYELLYKRKDEKEEKRVSFESTTTYLLK--DLRPFTTYSFQLAARSRHGIGAYTNEISAETPQ-TQPSAPPQ--EVTCSSPSSTNILVSWKPP--PVELQNGIIIKYTIQYAATEGEDTTTREIS-EIPPENVQYLLENLEKWTEYRVTVTAHTDVGPGPESLPQLIRTEEDVPSGPPRKVEVEAVNSSSVKVLWRSPVPNRQHGQIRGYQVHYVRMFNGEPVGHPVIKDILIDDAQWEYDDSTE-YEMVLTDLQAETTYSVTVAAYTTKGDGARSKPKLVTTM--GAVPEKP---RL--MVSPTNMGTALL----QWHPPPNTHGPLQGYRLRFGRKDVEPLTVIEFPEREN-------------HYTTK--EIHKGASYTFRLSARNKVGFGEETVKEISTSEDTPSGFPQSIVAESATTTTIQVSWQPVLLAERNGIIIKYALQYKDINSPRSPSELFIAAPESTVILDGLKADTTYDIKMCAFTSKGPGPYSPSIQFRTQPLDQVFAKNFHVKAAMKTSVLLTWEIPDNYNPAQPFTILYDNGQSVEVD---------GKLTQKLITNLQPETQYSFLLTNRG-NSAGGLQHRVSTMTAPDILRTKPYLIGKTNSDGMV 1123          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Cavefish
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668])

HSP 1 Score: 868.611 bits (2243), Expect = 0.000e+0
Identity = 405/604 (67.05%), Postives = 476/604 (78.81%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD++  LK NDN KF++EYESIDPG  FTW  SNLE+NK KNRYANVIAYDHSRV+LS ++ IPGSDYINANY DGYRKQNAYIATQG LPETF  FWRMVWE R A IVMMTKLEER RVKCDQYWPTRG+E Y    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QYVFI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY   LEYL SFD + +
Sbjct: 1322 NFQTPGMASHPPIPIMDLADHLERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKAKNRYANVIAYDHSRVLLSAIDGIPGSDYINANYIDGYRKQNAYIATQGSLPETFGDFWRMVWEQRSANIVMMTKLEERSRVKCDQYWPTRGTETYGL--IQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLANTKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFDHYAT 1909          

HSP 2 Score: 270.396 bits (690), Expect = 2.619e-72
Identity = 274/1036 (26.45%), Postives = 451/1036 (43.53%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQH-VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHI--PTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIK-VIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRH-NLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKN----TTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQ----IKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIESCNT----LDVGPVTMVTLGNVQYNSDYQV---GIKSKG 3228
            K +  P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   T  L V    + LP GFP   +     V +  +   M C   G      +WFKD  P++ +    R   LRSG++  ++  + D G YEC A N  G+  S    L +R   + P++   P D E+ PG  VN+TC A G+P P ++W+  ++   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P  +       T   ++W+  NPE   P   + +       +++    K+I  +           Y+V  L PY+ Y  +V+A +  +G    S+ I  +T E  PS+ P+ V     + T+  + W  P EANG+I  Y VYY+ +    +NQW+K      + + I  L  N TY+IKV A  S G GP+S    II + GVP QP +F+    + TSI L W +PPQ            +   I+G  +       KEE+       T Y + +L P T Y   LAAR+ HG+G  +N ++  T    P++ P  +   + S T+I + W+      E  +   IK  I+  + E  D +     +I  +P +        +Y++ +LE    Y++ + +    G     +  +++T     VPS PP  + +  +   +          + W  P+    HG IR Y++ +  +   + +   + +  L      +    T Y     +L     Y  +VAA  T   G   K   V+T  + P+   + +  T +   +  + W PP   N +G L  Y++    +G K+    T I      N Y   E + +   YTF++ A  KVG G    +   + +    D P     S + E+     I+V+W+   L+  N     G  I Y LQ   KDI S  +        P + V L  ++ ++ Y +      SKG
Sbjct:   30 KFLRTPNDQTGVQGGVASFICQATGDP--RPKIVWNKKGKRVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNTVGEISATTRLTVLREDQ-LPAGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTTNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDSEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGVIEAVAQITVKALPKPPGVLVVTERTATSITLTWDSGNPE---PVSYYIIQHKSKYSEDS---YKEIDGV-------ATTRYSVGGLSPYSDYEFRVVAVNN-IGRGPASEAIEDKTAEQAPSTAPRQVRGRMLSATTAIIHWEEPEEANGQIMGYRVYYTMDPSQHVNQWEKQIVRNANFLTIQGLTPNKTYYIKVLAYTSVGDGPLSSDLQIIAKTGVPSQPMDFKAEAKSETSILLSWVAPPQ----------SGQDNQITGYELLYKRKDEKEEKRVSFESTTTYLLKDLRPFTTYSFQLAARSRHGIGAYTNEISAETPQTQPSAPPQEVTCSSPSSTNILVSWKP--PPVELQNGIIIKYTIQYAATEGEDTTTR---EISEIPPEN------VQYLLENLEKWTEYRVTVTAHTDVGPGPESLPQLIRTE--EDVPSGPPRKVEVEAVNSSS--------VKVLWRSPVPNRQHGQIRGYQVHYVRMFNGEPVGHPVIKDILIDDAQWEYDDSTEYEMVLTDLQAETTYSVTVAAYTTKGDGARSKPKLVTTMGAVPEKPRLMVSPTNM--GTALLQWHPP--PNTHGPLQGYRL---RFGRKDVEPLTVIEFPERENHYTTKE-IHKGASYTFRLSARNKVGFG----EETVKEISTSEDTPSGFPQSIVAESATTTTIQVSWQPVLLAERN-----GIIIKYALQY--KDINSPRSPSELFIAAPESTVILDGLKADTTYDIKMCAFTSKG 997          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Cavefish
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668])

HSP 1 Score: 867.84 bits (2241), Expect = 0.000e+0
Identity = 405/604 (67.05%), Postives = 476/604 (78.81%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPPIP   LAD++  LK NDN KF++EYESIDPG  FTW  SNLE+NK KNRYANVIAYDHSRV+LS ++ IPGSDYINANY DGYRKQNAYIATQG LPETF  FWRMVWE R A IVMMTKLEER RVKCDQYWPTRG+E Y    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QYVFI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY   LEYL SFD + +
Sbjct:  895 NFQTPGMASHPPIPIMDLADHLERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKAKNRYANVIAYDHSRVLLSAIDGIPGSDYINANYIDGYRKQNAYIATQGSLPETFGDFWRMVWEQRSANIVMMTKLEERSRVKCDQYWPTRGTETYGL--IQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLANTKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFDHYAT 1482          

HSP 2 Score: 243.047 bits (619), Expect = 3.968e-64
Identity = 204/721 (28.29%), Postives = 324/721 (44.94%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQH-VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHI--PTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSG---------LSAPFIFDIVKTRP 2331
            K +  P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   T  L V    + LP GFP   +     V +  +   M C   G      +WFKD  P++ +    R   LRSG++  ++  + D G YEC A N  G+  S    L +R   + P++   P D E+ PG  VN+TC A G+P P ++W+  ++   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P  +       T   ++W+  NPE   P   + +       +++    K+I  +           Y+V  L PY+ Y  +V+A +  +G    S+ I  +T E  PS+ P+ V     + T+  + W  P EANG+I  Y VYY+ +    +NQW+K      + + I  L  N TY+IKV A  S G GP+S    II + GVP QP +F+    + TSI L W +PPQ            +   I+G  +       KEE+       T Y + +L P T Y   LAAR+ HG+G  +N ++  T   +        V+    TS+ + W    DN      F I     +S+E VD                     + + +I +L+    Y  +L + G+S          ++AP   DI++T+P
Sbjct:   15 KFLRTPNDQTGVQGGVASFICQATGDP--RPKIVWNKKGKRVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNTVGEISATTRLTVLREDQ-LPAGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTTNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDSEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGVIEAVAQITVKALPKPPGVLVVTERTATSITLTWDSGNPE---PVSYYIIQHKSKYSEDS---YKEIDGV-------ATTRYSVGGLSPYSDYEFRVVAVNN-IGRGPASEAIEDKTAEQAPSTAPRQVRGRMLSATTAIIHWEEPEEANGQIMGYRVYYTMDPSQHVNQWEKQIVRNANFLTIQGLTPNKTYYIKVLAYTSVGDGPLSSDLQIIAKTGVPSQPMDFKAEAKSETSILLSWVAPPQ----------SGQDNQITGYELLYKRKDEKEEKRVSFESTTTYLLKDLRPFTTYSFQLAARSRHGIGAYTNEISAETPQTLFAK--NFHVKAAMKTSVLLTWEIP-DNYNPAQPFTILYDNGQSVE-VDGK-------------------LTQKLITNLQPETQYSFLLTNRGNSAGGLQHRVSTMTAP---DILRTKP 681          

HSP 3 Score: 60.077 bits (144), Expect = 3.089e-8
Identity = 48/175 (27.43%), Postives = 82/175 (46.86%), Query Frame = 1
Query: 2611 YEFSVAAMNTADIG-LEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYG-------LKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTW---ELSHTNNIKVVGFKIYY 3102
            YEF V A+N    G     +   T E AP + P  +    +++ +  I W+ P  E  NG ++ Y+V Y+T          +   +R  +    +  I+GL  N  Y  +V A+T VG GP SSD+       +P  P++ +A   +E  I ++W     S  +N ++ G+++ Y
Sbjct:  366 YEFRVVAVNNIGRGPASEAIEDKTAEQAPSTAPRQVRGRMLSATTAIIHWEEP--EEANGQIMGYRV-YYTMDPSQHVNQWEKQIVRNAN----FLTIQGLTPNKTYYIKVLAYTSVGDGPLSSDLQIIAKTGVPSQPMDFKAEAKSETSILLSWVAPPQSGQDN-QITGYELLY 532          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Cavefish
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668])

HSP 1 Score: 867.84 bits (2241), Expect = 0.000e+0
Identity = 406/609 (66.67%), Postives = 477/609 (78.33%), Query Frame = 1
Query: 4396 SSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            S   SN   + +  HPPIP   LAD++  LK NDN KF++EYESIDPG  FTW  SNLE+NK KNRYANVIAYDHSRV+LS ++ IPGSDYINANY DGYRKQNAYIATQG LPETF  FWRMVWE R A IVMMTKLEER RVKCDQYWPTRG+E Y    + +  L+TVELA Y +R F+L K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L +I+HEK VD+YG V+ +RAQRNYMVQTE+QYVFI+DALLEA  CGNTEV  R+L+A++ KL Q         + +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY   LEYL SFD + +
Sbjct: 1331 SGYPSNLHLSSMASHPPIPIMDLADHLERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKAKNRYANVIAYDHSRVLLSAIDGIPGSDYINANYIDGYRKQNAYIATQGSLPETFGDFWRMVWEQRSANIVMMTKLEERSRVKCDQYWPTRGTETYGL--IQVTLLDTVELATYCVRTFALYK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ-------IETGENVTGMELEFKRLANTKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFDHYAT 1923          

HSP 2 Score: 271.166 bits (692), Expect = 1.972e-72
Identity = 274/1036 (26.45%), Postives = 451/1036 (43.53%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQH-VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHI--PTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIK-VIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRH-NLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKN----TTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQ----IKVTWE---LSHTNNIKVVGFKIYYCLQTIPKDIESCNT----LDVGPVTMVTLGNVQYNSDYQV---GIKSKG 3228
            K +  P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   T  L V    + LP GFP   +     V +  +   M C   G      +WFKD  P++ +    R   LRSG++  ++  + D G YEC A N  G+  S    L +R   + P++   P D E+ PG  VN+TC A G+P P ++W+  ++   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P  +       T   ++W+  NPE   P   + +       +++    K+I  +           Y+V  L PY+ Y  +V+A +  +G    S+ I  +T E  PS+ P+ V     + T+  + W  P EANG+I  Y VYY+ +    +NQW+K      + + I  L  N TY+IKV A  S G GP+S    II + GVP QP +F+    + TSI L W +PPQ            +   I+G  +       KEE+       T Y + +L P T Y   LAAR+ HG+G  +N ++  T    P++ P  +   + S T+I + W+      E  +   IK  I+  + E  D +     +I  +P +        +Y++ +LE    Y++ + +    G     +  +++T     VPS PP  + +  +   +          + W  P+    HG IR Y++ +  +   + +   + +  L      +    T Y     +L     Y  +VAA  T   G   K   V+T  + P+   + +  T +   +  + W PP   N +G L  Y++    +G K+    T I      N Y   E + +   YTF++ A  KVG G    +   + +    D P     S + E+     I+V+W+   L+  N     G  I Y LQ   KDI S  +        P + V L  ++ ++ Y +      SKG
Sbjct:   30 KFLRTPNDQTGVQGGVASFICQATGDP--RPKIVWNKKGKRVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNTVGEISATTRLTVLREDQ-LPAGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTTNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDSEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGVIEAVAQITVKALPKPPGVLVVTERTATSITLTWDSGNPE---PVSYYIIQHKSKYSEDS---YKEIDGV-------ATTRYSVGGLSPYSDYEFRVVAVNN-IGRGPASEAIEDKTAEQAPSTAPRQVRGRMLSATTAIIHWEEPEEANGQIMGYRVYYTMDPSQHVNQWEKQIVRNANFLTIQGLTPNKTYYIKVLAYTSVGDGPLSSDLQIIAKTGVPSQPMDFKAEAKSETSILLSWVAPPQ----------SGQDNQITGYELLYKRKDEKEEKRVSFESTTTYLLKDLRPFTTYSFQLAARSRHGIGAYTNEISAETPQTQPSAPPQEVTCSSPSSTNILVSWKP--PPVELQNGIIIKYTIQYAATEGEDTTTR---EISEIPPEN------VQYLLENLEKWTEYRVTVTAHTDVGPGPESLPQLIRTE--EDVPSGPPRKVEVEAVNSSS--------VKVLWRSPVPNRQHGQIRGYQVHYVRMFNGEPVGHPVIKDILIDDAQWEYDDSTEYEMVLTDLQAETTYSVTVAAYTTKGDGARSKPKLVTTMGAVPEKPRLMVSPTNM--GTALLQWHPP--PNTHGPLQGYRL---RFGRKDVEPLTVIEFPERENHYTTKE-IHKGASYTFRLSARNKVGFG----EETVKEISTSEDTPSGFPQSIVAESATTTTIQVSWQPVLLAERN-----GIIIKYALQY--KDINSPRSPSELFIAAPESTVILDGLKADTTYDIKMCAFTSKG 997          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Cavefish
Match: ptprfb (protein tyrosine phosphatase receptor type Fb [Source:NCBI gene;Acc:799867])

HSP 1 Score: 858.596 bits (2217), Expect = 0.000e+0
Identity = 394/604 (65.23%), Postives = 474/604 (78.48%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            N++   + +HPPIP   LAD+I  LK ND  +F++EYESIDPG  FTW  SN+E+NKPKNRYANVIAYDHSRV+L++++ +PGSDYINANY DGYRKQNAYIATQGPLPET   FWRMVWE R + IVMMT+LEE+ RVKCDQYWP RG+E Y    + +  L+TVELA Y++R F+L K      NGS E R++  FQF  WPDHGVP+   P+L F++RV++C P D+GP+VVHCSAGVGRTG  IV+D+ L +++HEK VD+YG V+ +R+QRNYMVQTE+QYVFI++ALLEA+ CGNTEV  R+L+AH+ KL QP       P     T MELEFK L+       +F +ANLP N+ KNRL+NI+P+E  RVCLQPIR  +GSDYINAS IDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RTIRQFQF DW EQGVP++GE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VDLFQTV+ LR QRP MVQTEDQYQ CY  ALEYL SFD + +
Sbjct: 1224 NYQTPGMREHPPIPVSDLADHIERLKANDGLRFSQEYESIDPGQQFTWENSNMEVNKPKNRYANVIAYDHSRVILTSVDAVPGSDYINANYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTRLEEKSRVKCDQYWPIRGTETYGM--IQVTMLDTVELATYSVRTFALYK------NGSSEKREIRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCLIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGNTEVPARNLYAHIQKLSQP-------PPGDTVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFETSRVCLQPIRGVEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1811          

HSP 2 Score: 171.785 bits (434), Expect = 4.076e-42
Identity = 137/496 (27.62%), Postives = 228/496 (45.97%), Query Frame = 1
Query:  256 IIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKY-----VIPIP--SGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDN--APLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKE------SILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHV-RITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPG 1692
             +  P+ QT + G  A F CQ  G+P   ++ +  G K       VI     SG +LRI  ++    + +  +C   N + +   +A L V                +++ Y G     +K+ C   G       W  ++  +PL  S P    + SG++  +   + D G YEC A+N  G+  S    L +R   + P++   P + EV PG  +NLTC A G P P ++W+        +LT +E      ++L LT+I + A+Y C A +S+G+++   QV VK +PK P ++T      T   ++W+  NPE   P   + +     + DN+   +  +              Y++  L PY+ Y  +V+A +  +G   PS  +   T E  PSSPP SV A   + +++ V+W PP E NG+I  Y +YY+ +    ++ W K  T    +  I+ L T+ TY ++V    S G GP S+   +  + G
Sbjct:    4 FVKTPEDQTGISGGVASFVCQAVGDPKPRITWMKKGKKVSSQRFEVIEFDGGSGSVLRIQPLRTHRDEAI-YECTATNSAGDINTSAKLTV----------------LEEQYFGVF---VKL-CGGAGRPRDAVGWRMNSIYSPLFCS-PAIHQVSSGALQIENSEESDQGKYECVAMNSAGTRYSAPANLYVRVRRVPPRFSIPPTNQEVMPGGSINLTCVAVGAPMPYVKWMVGE----VELTKEEEMPIGRNVLELTNIRQSANYTCVAISSLGMVETVAQVTVKALPKPPTSLTVTETTATSVTLTWDSGNPE---PVSYYMIQYRSKATDNSFQEVDGVATTR----------YSIGGLSPYSEYEFRVMAVNN-IGRGPPSDPVETRTGEQAPSSPPLSVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTTDPDTQLSAWHKHNTDDSRLTTISGLITDVTYSLRVLGFTSVGDGPPSDVLQVKTQQG 459          

HSP 3 Score: 130.183 bits (326), Expect = 1.584e-29
Identity = 213/915 (23.28%), Postives = 365/915 (39.89%), Query Frame = 1
Query:  445 RIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPIND---------LTDKESILLLTDITEPASYICRANN-SMGVIQHAVQVRV-KKIPKIP-VNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFT---SITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVR---PGVPPQPHNFRGAGITSTSINLIW-SPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNSP-IGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTI 3117
            + +C+  N SA  + +A  N+    + +P   PRF +         G ++ + C V  G P+ +  W      L   E     +  G    +      S  Y C AI+ +G + ++  ++ ++  P  P  +     V       V LT  + GNP P   ++ QY     D          T + SI  L+  +E    +   NN   G     V+ R  ++ P  P +++    +  +   + WE       P E     I    I  T     Q+   H    D+  +T  ++ L     YS++V+ F+ ++GD  PS  + ++T++       Q++Y           I V + P             +Y+                     +  L  N  Y   + A +  G G  ++P         P  PPQ  + R   ++STSI + + +PP       ++ Y + Y+  SG+     T + E   I  D   Y +  L   T Y + + A T+ G G  S  + ++T   VP +P   ++V  L+ T+I + W+  + N++   I  +++   +L++ E     N + V +           +  E +I  L +  +Y + + +  + G  A     ++KT     VP  P  I        T  G T L   I W PP +  G +  Y++R+  V      E+   R L        VTG         L  G  Y F ++A N A  G E    +ST+E AP  +P++  + G+T+ +  ++W+PP +   NG +VNY V Y     +  +  T ST      I GL+ +  Y  +V+AFT  G GP S  +  RT+   P    +     + +  + +TWEL   N    V FKI Y  Q++
Sbjct:  153 KYECVAMN-SAGTRYSAPANLYVRVRRVP---PRFSIPPTNQEVMPGGSINLTC-VAVGAPMPYVKWMVGEVELTKEEE----MPIGRNVLELTNIRQSANYTCVAISSLGMVETVA-QVTVKALPKPPTSL----TVTETTATSVTLTWDS-GNPEPVSYYMIQYRSKATDNSFQEVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSDPVETRTGEQAPSSPPLSVQARMLSASTMLVQWE-------PPEEPNGQIRGYRIYYTTDPDTQLSAWHKHNTDDSRLT-TISGLITDVTYSLRVLGFT-SVGDGPPSDVLQVKTQQ--GGCDLQTLYFFKFMLFFFPQILVTFDP-----------AGFYA---------------------VEGLKPNTLYKFSLAARSDMGLGVFTKPIEARTAQSTPSAPPQ--DVRLESLSSTSIKVSYVAPPAASRHGAIVRYSISYQAASGED----TERHEVKDIGVDTLSYVLDGLEKWTEYKVCVRAHTDVGPGPESPAVRIKTREDVPGAPPRKLEVEALNSTAIRVTWKPPLSNKQHGQIRGYQVIYSRLENGEPRGQPNILDVAL----------PEAQEAVITGLLSETSYSVTVAAYTTKGDGARSKAKVIKTT--GAVPGKPTMI------ISTTVGNTAL---IQWQPPKDMVGELVGYQLRYKRVDE----EAFTVRELRRTDDHYTVTG---------LYKGATYTFHLSARNRAGNGEEHVKEISTQEEAPSGFPLNFSVVGLTTTTTRLTWEPPALSERNGRIVNYVVVYRDINSQQNS--TNSTAETQMTIHGLKPDTTYDIRVQAFTSRGGGPISPSIQSRTMSTSPAFATSFGVKAVMKTSVLLTWELPE-NFKSQVPFKILYNQQSV 966          

HSP 4 Score: 58.151 bits (139), Expect = 1.219e-7
Identity = 107/447 (23.94%), Postives = 166/447 (37.14%), Query Frame = 1
Query:  538 FPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLR----SGSIFFDRLLK--EDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRW-LTQYHRP------INDLTDKESILLLTDITEPASYICRANNSMGVIQHA---VQVRVKKIP---KIP-----------VNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNV--YYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLI-WSPPQLPS 1779
             P F    +   G  G      C   G    +  W K      +S  R  ++     SGS+   + L+   D  IYEC A N  G I +   KL +    +  Q+           G  V L C   G P   + W +   + P      I+ ++     +  ++ ++   Y C A NS G    A   + VRV+++P    IP           +N+TC+ +G     + W    E +L  E       ++ I   VL L                    T++R    Y+   I+   +LG  +    + +  K LP   PP S+  T  T TS+T+ W      N +   Y +  Y S+   +   +     TTR    I  L   + Y  +V AVN+ G GP S+P         P  P     A + S S  L+ W PP+ P+
Sbjct:    1 MPTFVKTPEDQTGISGGVASFVCQAVGDPKPRITWMKKGK--KVSSQRFEVIEFDGGSGSVLRIQPLRTHRDEAIYECTATNSAGDI-NTSAKLTV----LEEQYF----------GVFVKL-CGGAGRPRDAVGWRMNSIYSPLFCSPAIHQVSSGALQIENSEESDQGKYECVAMNSAGTRYSAPANLYVRVRRVPPRFSIPPTNQEVMPGGSINLTCVAVGAPMPYVKWMVG-EVELTKEE------EMPIGRNVLEL--------------------TNIRQSANYTCVAIS---SLGMVETVAQVTV--KALP--KPPTSLTVTETTATSVTLTWD---SGNPEPVSYYMIQYRSKATDNSFQEVDGVATTR--YSIGGLSPYSEYEFRVMAVNNIGRGPPSDPVETRTGEQAPSSPPLSVQARMLSASTMLVQWEPPEEPN 390          

HSP 5 Score: 54.299 bits (129), Expect = 1.814e-6
Identity = 73/310 (23.55%), Postives = 118/310 (38.06%), Query Frame = 1
Query: 1078 IPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPI--EANGKITDYNVYYSRNLQHPINQWQKS--ETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIP-TLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRT 1992
            +P  P  I    +G T A I W+  P  D+  E     +    +D     ++++           +  Y VT L     Y+  + A ++     +  K I   T+E  PS  P +      T T+  + W PP   E NG+I +Y V Y       IN  Q S   T    + I  L  + TY I+V A  S G GP+S           P    +F    +  TS+ L W   +LP                   +P  +   ++ +++  +     +T L P+T Y   L +R     G+   +++RT
Sbjct:  733 VPGKPTMIISTTVGNT-ALIQWQ--PPKDMVGELVGYQLRYKRVDEEAFTVREL--------RRTDDHYTVTGLYKGATYTFHLSARNRAGNGEEHVKEI--STQEEAPSGFPLNFSVVGLTTTTTRLTWEPPALSERNGRIVNYVVVY-----RDINSQQNSTNSTAETQMTIHGLKPDTTYDIRVQAFTSRGGGPISPSIQSRTMSTSPAFATSFGVKAVMKTSVLLTW---ELPENFK-------------SQVPFKILYNQQSVEVQGNLKRKLITGLKPDTNYSFVLMSRGNSAGGLQQQVSIRT 1008          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Sea Lamprey
Match: ptpra (protein tyrosine phosphatase receptor type A [Source:ZFIN;Acc:ZDB-GENE-020107-1])

HSP 1 Score: 543.117 bits (1398), Expect = 1.413e-171
Identity = 276/597 (46.23%), Postives = 382/597 (63.99%), Query Frame = 1
Query: 4435 KHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGH-HFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQG--PLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            K+PP+    L +       +DN  F EE+ S+       T   ++ E NK KNRY N++ YD+ RV L++L  +P SDYINA+Y +GY+++N +IA QG  P  ET   +WRM+WE   A IVM+T L+ER   KC QYWP +G   Y    +S+  +    L  YT+RKF L + +   PN  K  R +  F FT WPD GVP   + +L F+K+V++C P  +GPIVVHCSAGVGRTG +IV+D+ L  IQ E+ VDV+G V+R+RAQR  MVQT+ QYVFIY ALLE  L G+TE+ +  L +H+ KL         TP+    TG+E EFK L+ +  +  +  T NLP N  KNR++ I+PY+  RV +   R ++ +DYIN SFIDGYR + A++A QGPL  T+ DFWRM+W+  S  +VML++L E G+EKC++YWPTE + T+G II+E   E +  S+ +R+F V ++  E  +R IRQF F  W E G+P  G+ +I  I  V K ++  G   PITVHCSAG GRTG F AL  +L+R+++EG +D+FQTV+ LR QRP MVQT +QY+FCY    EY+ +F  +
Sbjct:  163 KYPPLAVDRLEEEFNRRSADDNKLFREEFNSLPSCPIQATCEAASKEENKEKNRYVNILPYDNFRVHLTSLEGVPDSDYINASYVNGYQEKNKFIAAQGKGPKEETLNDYWRMIWELNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNLRVSVEDVTV--LVDYTIRKF-LIQVVGDIPN-KKPPRLITQFHFTSWPDFGVPFAPIGMLKFLKKVKTCNPPYAGPIVVHCSAGVGRTGTFIVIDAMLDMIQTERKVDVFGFVTRIRAQRCQMVQTDMQYVFIYQALLEFQLYGDTELEVTSLESHLQKLYNK-----NTPTG--CTGLEDEFKKLTTVKIQNEKMRTGNLPANMKKNRVLQIIPYDFNRVIIPMKRGEEFTDYINGSFIDGYRQKDAFLAGQGPLQQTVEDFWRMVWEWRSCSIVMLTELEERGQEKCARYWPTEGTITYGDIIIELKQENSHDSYTVRDFSVSNT-RENKSRQIRQFHFHGWPEIGIPEDGKGMISLIAAVQKQQQHTGNH-PITVHCSAGAGRTGTFCALCTILERVKTEGILDVFQTVKSLRTQRPHMVQTLEQYEFCYKVVQEYIEAFSDY 746          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Sea Lamprey
Match: ptprsa (protein tyrosine phosphatase receptor type Sa [Source:ZFIN;Acc:ZDB-GENE-020107-3])

HSP 1 Score: 483.411 bits (1243), Expect = 3.553e-152
Identity = 245/447 (54.81%), Postives = 303/447 (67.79%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPS--DSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDV--YGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRS-QKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGR 5736
            N +   +  HPPIP    A ++  LK NDN  F++EYESIDPG  FTW  SNLEINK KNRYANV+AYDHSRV+L T++ +PGSDYINANY DGYR+ NAYIA+QGPL +T   FWRMVWE R + IVMMTKLEER RVKCDQYWP RGSE+Y    +++   +TVELA Y+ R F+LT+      +G  E RDV  FQFT WPDHGVP+   P+L F++RVR+   S  D GP++VHC       G + V      Q  H   + V  Y  V+ +RAQRNYMVQTEEQY F++ AL+EA   G TE   R LHAH+ +L Q      V+ +   +TG+ LEF+ L     R     +  LP N+LKNRL+ ++P ++ RV LQ IR   GSDYINAS+IDGYRS Q+AYIATQGPL  T  D WRMLW+ NS+IVVML++LREMGR
Sbjct:  168 NHQTPGMEMHPPIPVSEFAGHVERLKANDNMLFSQEYESIDPGQQFTWDHSNLEINKHKNRYANVVAYDHSRVILHTIDGVPGSDYINANYIDGYRRHNAYIASQGPLADTVADFWRMVWEQRSSTIVMMTKLEERARVKCDQYWPNRGSESYGLVQVTLT--DTVELATYSTRSFTLTR------SGCTERRDVRQFQFTAWPDHGVPEFPTPVLAFLRRVRAAWGSSADGGPLIVHCRQRSDVCGCFFV--GLFMQEGHYGCITVSLYLQVTCMRAQRNYMVQTEEQYAFVHTALVEAVSSGCTETPARSLHAHLQRLSQ-----SVSHTEPRTTGLHLEFQRLQMSKLRVSTAPSGALPCNKLKNRLLTVIPPDSSRVALQAIRGTQGSDYINASYIDGYRSQQRAYIATQGPLPETTEDLWRMLWEQNSTIVVMLTKLREMGR 599          

HSP 2 Score: 188.348 bits (477), Expect = 3.110e-50
Identity = 97/247 (39.27%), Postives = 138/247 (55.87%), Query Frame = 1
Query: 5464 FNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSS 6204
            ++ +NL  N+ KNR  N++ Y++ RV L  I    GSDYINA++IDGYR   AYIA+QGPLA+T+ DFWRM+W+  SS +VM+++L E  R KC QYWP   S ++G + V       + ++  R F +  S   T  R +RQFQF  W + GVP     ++ F+ +V          GP+ VHC       G F     + +      TV L+  V  +R QR  MVQTE+QY F +   +E +SS
Sbjct:  215 WDHSNLEINKHKNRYANVVAYDHSRVILHTIDGVPGSDYINANYIDGYRRHNAYIASQGPLADTVADFWRMVWEQRSSTIVMMTKLEERARVKCDQYWPNRGSESYGLVQVTLTDTVELATYSTRSFTLTRSGC-TERRDVRQFQFTAWPDHGVPEFPTPVLAFLRRVRAAWGSSADGGPLIVHCRQRSDVCGCFFVGLFMQEGHYGCITVSLYLQVTCMRAQRNYMVQTEEQYAFVHTALVEAVSS 460          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Sea Lamprey
Match: ca16b (carbonic anhydrase XVI b [Source:ZFIN;Acc:ZDB-GENE-080818-1])

HSP 1 Score: 398.282 bits (1022), Expect = 8.738e-121
Identity = 236/615 (38.37%), Postives = 336/615 (54.63%), Query Frame = 1
Query: 4447 IPSGHLADYIAALKTNDNAKFTEEYESI-----DPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTL--NDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSL-TKKL------SSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHC--SAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPL------PVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSA------TFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGE-SLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSS 6204
            +P    A ++  +       F++E+E +     D G   T   SN   NK KNRY N++AYDHSRV L  L   D   SDYINANY DGY +Q AYIA QGPL  TF  FWRMVWE    +IVM+T L E+ R KCDQYWP+  +E Y    +++    T  LA YT+R F++   KL       S   G +  R V  F +T WPD G PD ALP+L F+++  +      GP+VVHC  SAGVGRTG YIVLDS L QI+    V+V G +  +R QRNY+VQ +EQY FI+++LLEA L G TEV+   LHA+ T +  P       PV+  T     +T +E +F+ +++ S R  +F +A    N+ KNR  +I+P E  RV L  +   +G+DYINAS+I GY     +I TQ PL +T  DFWRM+W HN+ I+VML   + +  ++ S YWP    A      T   I  + +   N    ++ +F +     + +   +R +Q   W +   P S    +I+ I +   T+     +GP  +H   G    G F AL+ +L ++  + +VD+FQ  +++ + RP +    +QY F Y  AL  + +
Sbjct:   71 LPVKLFARHVGEMHEGALHSFSQEFEEVQRCTADLG--ITAEHSNHPENKHKNRYVNIVAYDHSRVRLRPLPGKDSKHSDYINANYVDGYNRQKAYIAAQGPLKATFADFWRMVWEQNTGIIVMITNLVEKGRRKCDQYWPSESNEEYGNILVTLKSTRT--LACYTVRHFTIRNTKLRKGTSQKSSARGRQNERLVVQFHYTQWPDMGTPDYALPVLTFVRKSSATRTDLMGPVVVHCRRSAGVGRTGTYIVLDSMLQQIRDSGTVNVLGFLKHIRTQRNYLVQPQEQYTFIHESLLEAVLTGETEVAPGQLHAYYTSILSPAATDVTRPVVTATE----NTHLEKQFRLVTQCSVRQSEFFSATKHCNKEKNRNSSIVPVERSRVGLSSLSGLEGTDYINASYITGYYRSNEFIVTQHPLPHTTRDFWRMIWDHNAQIIVMLPDGQGLAEDE-SVYWPGREEAMNCDDFTVTLINEDRLCLANEEQLVIHDF-ILECLQDDYVLEVRHYQCPRWPDTEGPLSNAFEIINVIREEATTR-----DGPTILHDEFGGVSAGTFCALTTLLHQLEEQESVDVFQVCKMVNLMRPGVFTDIEQYHFVYRAALSLIGT 670          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Sea Lamprey
Match: ptprk (protein tyrosine phosphatase receptor type K [Source:ZFIN;Acc:ZDB-GENE-030131-9834])

HSP 1 Score: 416.772 bits (1070), Expect = 3.371e-120
Identity = 236/594 (39.73%), Postives = 339/594 (57.07%), Query Frame = 1
Query: 4438 HPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELS--TRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPS-FILREFRVRH-SDSETHNRTIRQFQFLDW-AEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSS 6204
            HP +    L ++I  +KT +   F EEYES   G    W  +  + N+ KNRY N+IAYDHSRV+L+ L++   SDYINANY DGY + + YIATQGPLP+T   FWRM+W+ R A I+M+T L E  R+KC +YWP  GS+ Y +  + +   +T  L+ Y +R F + +       G ++ R+V  F FTGWPDHGVP  A  LL FI+R+++  P  +GP+VVHCSAG GRTG Y+V+D  L   + E V+D+Y  V  LR +R  MVQTEEQYVFI+DA+LEA LCG+T +      A   ++ +P P          S  ++ EF+ L+ ++   R    + A LP N  KNR  ++LP  +R +      N D S+YINA+ +D YR   A+I TQ PL NT+ DFWR+++ ++ + +VML++L     + C QYWP E     G I VE  V +NM    I R FR+ + +  +   R + QF +L W A + VP S  S +  +    + +E++G +G   VHC     R      LS++         + + + V  +      +V  + QYQFCY  ALEYL +
Sbjct:  895 HPAVRVADLLEHIGQMKTGEGYGFKEEYESFFEGQSAPWDVAKRDENRAKNRYGNIIAYDHSRVMLNVLDEEQNSDYINANYVDGYYRTHHYIATQGPLPDTVGGFWRMIWQERSASIIMVTNLVEVGRIKCCKYWPD-GSDVYGD--IKVTLADTEMLSEYIIRTFRVERA------GQEDIREVRQFHFTGWPDHGVPYHATGLLAFIRRIKALDPPHAGPLVVHCSAGAGRTGCYMVIDIMLDMAESEGVIDIYNCVRELRTRRVNMVQTEEQYVFIHDAMLEACLCGDTCIPAGDFRAAYAEMLRPDP-------QSSSNHIKDEFQTLNMVTPPLRVEDCSIALLPRNHEKNRYHDVLP-PDRCLPFLITINGDSSNYINAALMDSYRQPSAFIVTQHPLPNTVKDFWRLVFDYHCTSIVMLNELDS--NKYCPQYWPEEGMLCHGPIQVE-FVAFNMEGDIITRTFRICNVARPQDGCRMVEQFHYLGWPAGREVPTSRHSFLRLVLAAERWREEYGMDGRTVVHCLNPPPRLLSLPLLSLMATANNHMYQIIITELVEKIMAIYKGLVNLQSQYQFCYDVALEYLET 1468          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002738.1 (pep scaffold:Pmarinus_7.0:GL477626:22501:55781:-1 gene:ENSPMAG00000002497.1 transcript:ENSPMAT00000002738.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 379.793 bits (974), Expect = 4.273e-116
Identity = 223/584 (38.18%), Postives = 322/584 (55.14%), Query Frame = 1
Query: 4441 PPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCD--GYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHC--SAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSEL--STRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDG--SDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRV----RHSDSETHNRTIRQFQFLDW-AEQGVPRSGESLIDFIGQVHKTKEQFG-QEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQ 6150
            P I    L  +I  +K+ +   F EEYES   G    W  +  + N+ +NRY N+IA  HS+ +      +   DY  A Y +  GY+KQ  YIATQGPL ET   FWRMVW+ + + IVM+T L E  RVKC +YWP    +      +++  L T  LA Y +R FS+ +K      G  +  +V  F FTGWPDHGVP  A  LL F++RV++  P ++GPI+ HC  SAG GRTG Y+V+D  L     E V+DVY  V  LR QR  MVQTEEQYVFI+D LLEA LCG+T +   +  +   +L +  P         +ST ++ EF  L+ +  + R    + A LP N  KNR+   LP +    CL  +   +G  S+YINA+ +D Y    A+I TQ PL NT+ DFWR+++ ++ + V+ML+++R    E C QYWP E S  +G + VE +        I R FR+    R  D     + ++  Q+L W + +  P S  S +   G+V +   +   +EG   VHC +G GR+G + A+S++ D ++ +  VD+F  V+ LR  +P MV+
Sbjct:    1 PAIRVADLLQHIGQMKSTEGCGFKEEYESFLDGQSAPWQVAKKDENRGRNRYGNIIALKHSQKLKVRKQRVLSQDYTEA-YVEQHGYQKQRQYIATQGPLQETAVDFWRMVWQEKSSSIVMVTNLVEVGRVKCFKYWP---DDTQQLGDIAVTLLHTELLAEYVIRTFSVKRK------GYFDALEVRQFHFTGWPDHGVPAFATGLLSFVRRVKASNPPEAGPIITHCRDSAGAGRTGCYVVIDVMLEMAGREGVIDVYNCVRELRLQRVNMVQTEEQYVFIHDVLLEACLCGDTAIPAANFRSAYLELTRLDP-------QTHSTPLKEEFMTLNTVTPALRAEDCSIALLPRNSSKNRVKEALPPDR---CLPFLLTLEGDSSNYINAALLDSYHRPSAFIVTQHPLPNTVKDFWRLVFDYHCTSVIMLNEMRP--SETCPQYWPEEGSLQYGAVHVETLSCCRDGDIISRIFRIHNISRPQDGHREVQHVQHLQYLGWPSHRDAPASPLSFLRVAGRVRRWHAELAEEEGRTLVHCLSGGGRSGTYCAVSVLCDMVKGQSVVDVFTAVKTLRNNKPDMVE 562          

HSP 2 Score: 167.548 bits (423), Expect = 1.533e-43
Identity = 99/267 (37.08%), Postives = 149/267 (55.81%), Query Frame = 1
Query: 5410 GMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENR---RVCLQPIRNQDGSD-YINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHC--SAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALE 6192
            G + E++   +  + P Q   A   ENR +NR  NI+  ++    +V  Q + +QD ++ Y+      GY+ Q+ YIATQGPL  T VDFWRM+WQ  SS +VM++ L E+GR KC +YWP + +   G I V  +    +  +++R F V+          +RQF F  W + GVP     L+ F+ +V  +     + GPI  HC  SAG GRTG ++ + ++L+    EG +D++  VR LR+QR  MVQTE+QY F +   LE
Sbjct:   22 GFKEEYESFLDGQSAPWQ--VAKKDENRGRNRYGNIIALKHSQKLKVRKQRVLSQDYTEAYVEQH---GYQKQRQYIATQGPLQETAVDFWRMVWQEKSSSIVMVTNLVEVGRVKCFKYWPDD-TQQLGDIAVTLLHTELLAEYVIRTFSVKRK-GYFDALEVRQFHFTGWPDHGVPAFATGLLSFVRRVKASNPP--EAGPIITHCRDSAGAGRTGCYVVIDVMLEMAGREGVIDVYNCVRELRLQRVNMVQTEEQYVFIHDVLLE 279          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Yeast
Match: PTP1 (Phosphotyrosine-specific protein phosphatase; dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation [Source:SGD;Acc:S000002389])

HSP 1 Score: 130.568 bits (327), Expect = 4.666e-33
Identity = 99/287 (34.49%), Postives = 137/287 (47.74%), Query Frame = 1
Query: 4576 NKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCD----------GYRKQNAYIATQGPLPETFEAFWRMVWESRCAL----IVMMTKLEERLRVKCDQYWPTRGSEAYAE------------------SGLSINHLETVELA-YYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQI-----------QHEKVVDVYG------IVSRLRAQRNYMVQTEEQYVFIYDA 5286
            N  +NRY N++ Y+ +RV L TL+   G+DYINA+Y            GY     YIATQGP  +T++ FW+M + + C L    IVM+T L E  R KC QYWP  G +                      S L I  +   ++  YYT+    LT    +DP      + V HF F  W D   P+  +P++       S   S   PI+VHCSAGVGRTG +I LD  +                ++  + Y       IV +LR+QR  MVQT++Q++FIY A
Sbjct:   52 NDARNRYVNIMPYERNRVHLKTLS---GNDYINASYVKVNVPGQSIEPGY-----YIATQGPTRKTWDQFWQMCYHN-CPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLT---PTDP-LVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLN-SRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHA 324          

HSP 2 Score: 125.946 bits (315), Expect = 1.667e-31
Identity = 96/294 (32.65%), Postives = 135/294 (45.92%), Query Frame = 1
Query: 5482 PENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFID----------GYRSQKAYIATQGPLANTIVDFWRMLWQH---NSSIVVMLSQLREMGREKCSQYWP---TERSATFGQIIVEPMVEYNM---PSFILREFRVRHSDSETHN----------------RTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVL----------------DRMRSEGTVDLFQTVRL-LRMQRPCMVQTEDQYQFCYLTALEYLSSF 6207
            P N  +NR +NI+PYE  RV L+ +    G+DYINAS++           GY     YIATQGP   T   FW+M + +   ++ ++VM++ L E  REKC QYWP    + +         P    +M   PS +  EF   H   + +                 +T+  F F  W +   P     +++     H       +  PI VHCSAGVGRTG F+AL  ++                DR   E T DL + + L LR QR  MVQT+DQ+ F Y  A +YL+S 
Sbjct:   50 PRNDARNRYVNIMPYERNRVHLKTL---SGNDYINASYVKVNVPGQSIEPGY-----YIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLN---SRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAA-KYLNSL 331          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Yeast
Match: PTP2 (Nuclear phosphotyrosine-specific phosphatase involved in osmosensing; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; with Msg5p co-regulates the calcium signaling pathway [Source:SGD;Acc:S000005734])

HSP 1 Score: 98.9821 bits (245), Expect = 4.112e-21
Identity = 89/328 (27.13%), Postives = 130/328 (39.63%), Query Frame = 1
Query: 4585 KNRYANVIAYDHSRVVLSTLNDIPG-----------------------------SDYINANYCD--GYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSI-NHLETV-ELAYYTMRKFSLTKKLSSDPNGSK------------------ETRDVFHFQFTGWPD------------HGVPDTAL--PLLMFIKRVRSCCPSD---------------SGPIVVHCSAGVGRTGAYIVLDSQLSQI----QHEKVVDVYG--------IVSRLRAQRNYMVQTEEQYVFIYDALL 5292
            KNRY+N++ Y+HSRV L      P                              +DYINANY           YIATQ PLP T + FW+++  ++  +I+ +   +E    K D YW    + +Y+   + + N  E +  +    +R F + K    + N S+                  E   V+  Q+  W D            H V ++ L  P        +  C  D               S P++VHCSAG GRTG ++ LD  LS +     H   +DV+         IV+ LR QR  MVQ   QY+  Y+ALL
Sbjct:  411 KNRYSNILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLTQINPDFKYIATQAPLPSTMDDFWKVITLNKVKVIISLNSDDELNLRKWDIYW---NNLSYSNHTIKLQNTWENICNINGCVLRVFQVKKTAPQNDNISQDCDLPHNGDLTSITMAVSEPFIVYQLQYKNWLDSCGVDMNDIIKLHKVKNSLLFNPQSFITSLEKDVCKPDLIDDNNSELHLDTANSSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIACYEALL 735          

HSP 2 Score: 82.4185 bits (202), Expect = 5.412e-16
Identity = 84/335 (25.07%), Postives = 127/335 (37.91%), Query Frame = 1
Query: 5497 KNRLINILPYENRRVCLQ-------------------------PIRNQDGS----DYINASFIDGYRSQK--AYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVE--YNMPSFILREFRVRHSDSETHNRT-----------------------IRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQF--------------------------------GQEGPITVHCSAGVGRTGVFLALSIVLDRM----RSEGTVD--------LFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLS 6201
            KNR  NILPYE+ RV L                          P+  ++ S    DYINA+++   +      YIATQ PL +T+ DFW+++  +   +++ L+   E+   K   YW    S +   I ++   E   N+   +LR F+V+ +  +  N +                       + Q Q+ +W +      G  + D I ++HK K                                       P+ VHCSAG GRTGVF+ L  +L  +         +D        +F  V  LR QR  MVQ   QY  CY   L Y +
Sbjct:  411 KNRYSNILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLTQINPDFKYIATQAPLPSTMDDFWKVITLNKVKVIISLNSDDELNLRKWDIYW-NNLSYSNHTIKLQNTWENICNINGCVLRVFQVKKTAPQNDNISQDCDLPHNGDLTSITMAVSEPFIVYQLQYKNWLDS----CGVDMNDII-KLHKVKNSLLFNPQSFITSLEKDVCKPDLIDDNNSELHLDTANSSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIACYEALLNYFA 739          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Yeast
Match: PTP3 (Phosphotyrosine-specific protein phosphatase; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm [Source:SGD;Acc:S000000877])

HSP 1 Score: 56.6102 bits (135), Expect = 4.098e-8
Identity = 42/126 (33.33%), Postives = 57/126 (45.24%), Query Frame = 1
Query: 4990 DVFHFQFTGWPDHGVPDTALPLLMFIKR---------VRSCCPSDSGP-IVVHCSAGVGRTGAYIVLDSQLSQ------IQHE--------KVVD-VYGIVSRLRAQRNYMVQTEEQYVFIYDALL 5292
            ++   Q   WPD G     + +L  I            R+   +D  P I+VHCSAG GRTG    +DS LS       +Q E        K+ D +   ++  R QR  MVQ   Q++FIYD LL
Sbjct:  751 ELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARNYYQNDQLPTILVHCSAGCGRTGTLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDPISWTINIFRKQRISMVQNINQFIFIYDCLL 876          

HSP 2 Score: 53.5286 bits (127), Expect = 3.572e-7
Identity = 40/127 (31.50%), Postives = 58/127 (45.67%), Query Frame = 1
Query: 4555 IQSNLEINKPKNRYANVIAYDHSRVVL--------------STLNDIPGSDYINANYCDGYR---KQNA-------------YIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYW 4845
            I S +E+   KNRY ++  Y+HSRV+L              ST +     +YINANY    R   +QN+             YIATQ P+P T   F+  +  +   L++ +T   E    KC +YW
Sbjct:  521 ISSGVELGA-KNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVEQNSSFQTTTTTTRRVRYIATQAPMPSTVHDFYTCILNNGVPLVLSLTNDFENGIEKCYRYW 646          

HSP 3 Score: 49.2914 bits (116), Expect = 7.005e-6
Identity = 36/117 (30.77%), Postives = 56/117 (47.86%), Query Frame = 1
Query: 5497 KNRLINILPYENRRVCLQP-------IRNQ----DGS---DYINASFIDGYR----------------SQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYW 5757
            KNR  +I PYE+ RV L+        I++     DG    +YINA+++   R                 +  YIATQ P+ +T+ DF+  +  +   +V+ L+   E G EKC +YW
Sbjct:  530 KNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVEQNSSFQTTTTTTRRVRYIATQAPMPSTVHDFYTCILNNGVPLVLSLTNDFENGIEKCYRYW 646          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Nematostella
Match: EDO46961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNP0])

HSP 1 Score: 708.753 bits (1828), Expect = 0.000e+0
Identity = 346/602 (57.48%), Postives = 433/602 (71.93%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            NF+   +  HPPI    L  +IA LK ++N++FT+EYESI+PG  FT   S +E NK KNRY N+ AYDHSRV LS +N I GSDYINAN+CDGYRK+ AYIATQGP+  T   FWRMVWE R   IVM+T+ EER RVKCDQYWPT G++ Y   G+ ++ ++ VELA YT+    + K+ +S P      R+V HFQFTGWPDHGVP    P L F++RV+   P D+GPIVVHCSAGVGRTG +IV+DS L +++HE+ VD+YG V+ LR QRNYMVQT+EQY+F +DA+LEA  CGNTEV  R+L  H+ KL +    LG        TG+E EFK +     +  ++  A L  NR KNRL NILPYE  RV + P+R  +GSDYINASFIDGYR +  +IATQGPL +T+ DFWRML + NS+I+VML+QL E   EKC +YWPT+RSA     IV+P+ E+  P F++R+F+V+ + S+T  R I+QF FL W E GVP+SGE +ID IGQV +  EQ  +EGPITVHCS GVGRTGVF AL IVL+RMRSEG VDLFQTV+LLR QRP MVQ+++QY FCY TALEYL SFD +
Sbjct: 1288 NFQTPAMIDHPPISVLDLPKHIAILKADNNSQFTQEYESIEPGQTFTADSSQMECNKGKNRYPNIHAYDHSRVRLSYINGIEGSDYINANFCDGYRKERAYIATQGPMQHTAADFWRMVWEQRTFTIVMLTREEERGRVKCDQYWPTDGTDVY--EGIEVSLVDWVELANYTISTLQICKEGASQP------REVKHFQFTGWPDHGVPAHPTPFLAFLRRVKFYNPPDAGPIVVHCSAGVGRTGCFIVIDSMLERLRHEETVDIYGHVTVLRTQRNYMVQTQEQYIFSHDAILEAVSCGNTEVHARNLLHHIKKLTE----LG----KGEVTGLEEEFKVVDPSQAKKHKYGAATLAINRPKNRLANILPYETTRVHISPVRGVEGSDYINASFIDGYRQRGLFIATQGPLQDTVDDFWRMLMEQNSNIIVMLTQLHEGEWEKCYKYWPTDRSARHQYYIVDPIAEHEYPQFVIRDFKVKDARSDT-VRNIKQFHFLGWPETGVPKSGEGIIDLIGQVQRAYEQQEEEGPITVHCSDGVGRTGVFTALFIVLERMRSEGVVDLFQTVKLLRTQRPAMVQSQEQYLFCYKTALEYLGSFDHY 1872          

HSP 2 Score: 211.846 bits (538), Expect = 8.968e-55
Identity = 232/1021 (22.72%), Postives = 420/1021 (41.14%), Query Frame = 1
Query:  307 FFCQIDGNPSFHLSLLYNGM-----KKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSG-SIFFDRLLKEDSGIYECRAINPVGSILSIK-------MKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILP--DRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRT-ENRVPNSPIGIDVRTLSPTSIAIRW-------RKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSH-GTIRAYRIRHNLVGPQN-----LIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMN-TADIGLEVKLNVSTRESAPDSYPVSID-ITGITSHSVNISWQPPLVENHNGILVNYQVAYF------------TYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIK--VVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGI 3231
              C + G+P   L+   NG      +  +  +P G ++RI  ++    K    +C   N      + +   +   +   P GFPR      F     G ++   C   G       WFKD  P+ L++PR ++L  G  +    L + D+G Y C A N +G + S +       + L +      P++  RPQD  V P   V L C+A+G+P P + W     R    ++ +   L++  I    +Y C A+++MG +Q    V V+ +P  P      +I     +I+W       + +      +   +    +  ++ + ++             V+ LRP++ Y  +V A + +LG S PS      T E  P S P+++ A   + TS    W PPI ANG+I  Y +YYS +L   I+QW+   ++     +T L    T+  ++ A N AG GP+SE   +  + GVP QP + + + ++ST+I + WSPP+ P              I G  +    +K++   ++         +  L P T+Y +++AA+++ GVG +S  +  RT E+R  ++P  I  R+   T++ I W       R G+    +I  ++ K  +     TVD +                       ++++L+   NY I + +    G   PF      +   ++    P ++R   +R    + +T     + W+PP     G I  Y + +  V  Q        +   + S+S + ++ ++TG         L     Y+  VAA     D    V     T   +PD   V ++  +G     V ++W+     +  G+ + Y+V Y                +K    ++ +T   +   + L   + Y F V   TK G  P +S            PP+N+ A  ++   ++VTW      N    ++G+ + Y       D+   N      +  V L  ++   +Y+V +++ G+
Sbjct:   20 MICNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRIGPLRAKIHKAT-YECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGRKLRITDLRESDNGKYSCVARNALGMVFSSQAMPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSR----ISGQNGELIIRGIQRSGNYSCIADSNMGRVQAYAYVTVRLLPFAPSRPNAASITSDAIKITWHPRGAHVVTSYEVQYRLKGKTEWQEITNVRGMQSL------------VVSGLRPFSSYEFRVFAVN-SLGRSRPSLMAEYTTSETKPGSAPRNIEAMGVSDTSFKAGWLPPISANGRIRGYRLYYSLDLLEDISQWRFMASSTNSTTVTGLTRQTTHFFRILAYNIAGDGPLSEVVAVKTQKGVPGQPRSVQLSVLSSTAIRVTWSPPRYPG-----------DGIFGYDVYYNKSKQDMDTVIGAFQMNTKEIMGLTPYTVYKVAVAAKSDKGVGPMSFVLTARTDEDRPSDAPQNIQGRSRDSTTLEISWDPPRPEHRNGLITHFTI-KYRAKGQRGAKYLTVDATKT-------------------SVVLHNLDKFTNYFIWVQASTKQG-DGPFSDKHTVSTAEDVPNGAPRDVR---IRVHNSTTMT-----VKWNPPTTKQDGKILGYMVFYTRVDDQGNQLRPPAQPESKDSMSEENHKVHLTG---------LAPETTYQIEVAAYTIKGDGARSVTRLAKTMAQSPDPPFVYLERASGDPISDVTLAWR----TSATGV-IEYKVRYAKSVRRLRGRDQGNLKMKEIKFKSHTTKQKF---QSLANGIWYLFNVSLRTKAGWSPETSRWIEIPPGPPSGPPLNVRAVAVSSTSVEVTWSAPDIWNRGGPILGYSVMYNPANKRGDVTVKNVTSPN-IFKVVLKRLKKFREYEVRVRAIGM 964          

HSP 3 Score: 93.5893 bits (231), Expect = 8.636e-19
Identity = 203/955 (21.26%), Postives = 375/955 (39.27%), Query Frame = 1
Query:  244 GAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM-----KKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGF------------PRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKG-------NPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICR--ANNSMGVIQHAVQVRVK----KIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWP--PDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHP---INQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVR-----PGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPN-SPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLK-NTTIRTTSTPNLYALI-EGLQENMLYTFQVRAFTKVGQGPWSSDVNFRT 2976
            G  +I   P  +    G+   F C   G P+ +++   + +        V  +  G  LRI D++ +D    +  C+ RN          L +   S+ +P               P F L       D   ++++ C   G       W  D +        R   ++G +    + +  SG Y C A + +G + +    + +R  P  P    RP    +     + +T   +G           +L+  T++   I ++   +S L+++ +   +SY  R  A NS+G  + ++         K    P NI  + +  T  +  W       LP  S    I    +      L  + +I  W     + N T  VT L   T +  +++A++   GD   S+ + ++T++  P  P +SV  +  + T+I V W+PP      I  Y+VYY+++ Q     I  +Q +        I  L     Y + V A +  G GP+S  F +  R     P   PQ  N +G    ST++ + W PP+   +  L+ +        G+         + + +   +T   +  L   T Y I + A T+ G G  S+   V T   VPN +P  + +R  + T++ ++W      ++     KI    +      D  N++    Q   +K     + ++  +  L     Y+I + +    G  A  +  + KT   +  P PP  + L +      S +TL     AW    ++ G I  Y++R+     +++     R   ++K+ E          +F  L  G  Y F+V+    A    E    +      P   P+++    ++S SV ++W  P + N  G ++ Y V Y     + + T++  ++PN++ ++ + L++   Y  +VRA   +G GP S     RT
Sbjct:  100 GFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGRKLRITDLRESDNG--KYSCVARNA---------LGMVFSSQAMPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGS--------RISGQNGELIIRGIQR--SGNYSCIADSNMGRVQAYAY-VTVRLLPFAPS---RPNAASI-TSDAIKITWHPRGAHVVTSYEVQYRLKGKTEWQE-ITNVRGMQS-LVVSGLRPFSSYEFRVFAVNSLGRSRPSLMAEYTTSETKPGSAPRNIEAMGVSDTSFKAGW-------LPPISANGRIRGYRL---YYSLDLLEDISQWRFMASSTNST-TVTGLTRQTTHFFRILAYN-IAGDGPLSEVVAVKTQKGVPGQP-RSVQLSVLSSTAIRVTWSPPRYPGDGIFGYDVYYNKSKQDMDTVIGAFQMNTK-----EIMGLTPYTVYKVAVAAKSDKGVGPMS--FVLTARTDEDRPSDAPQ--NIQGRSRDSTTLEISWDPPRPEHRNGLITHFTIKYRAKGQR------GAKYLTVDATKTSVVLHNLDKFTNYFIWVQASTKQGDGPFSDKHTVSTAEDVPNGAPRDVRIRVHNSTTMTVKWNPPTTKQDG----KILGYMVFYTRVDDQGNQLRPPAQP-ESKDSMSEENHKVHLTGLAPETTYQIEVAAYTIKGDGARSVTRLAKTMAQS--PDPPF-VYLERASGDPISDVTL-----AWR--TSATGVIE-YKVRY----AKSVRRLRGRDQGNLKMKEIKFKSHTTKQKFQSLANGIWYLFNVSLRTKAGWSPETSRWIEIPPGPPSGPPLNVRAVAVSSTSVEVTWSAPDIWNRGGPILGYSVMYNPANKRGDVTVKNVTSPNIFKVVLKRLKKFREYEVRVRAIGMLGMGPASEPFIDRT 978          

HSP 4 Score: 70.4774 bits (171), Expect = 8.123e-12
Identity = 131/568 (23.06%), Postives = 227/568 (39.96%), Query Frame = 1
Query: 1279 TYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPI--EANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVP-PQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXI--SGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNSP-IGIDVRTLSPTS-IAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPP--INSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTN-YCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGP 2949
            T  +  L PYT Y V V A S   G    S  +   T E  PS  PQ++   +   T++ + W PP     NG IT + + Y    Q    ++   + T+  V + +L     Y I V A    G GP S+   +     VP   P + R     ST++ + W+PP       +L Y++ Y  +   G  +      E +  +  +     +T L P T Y I +AA T  G G  S T   +T  + P+ P + ++  +  P S + + WR       +    + KV   KS+  +   ++ +++++ +  K+      ++ + N           +W + +  L     +    +R   I P PP    LN +R    S  ++   ++ W  P   N  G I  Y + +N   P N     KR  ++V    KNVT  N +      L   + YE  V A+    +G   +  +   +     +   +    + S  V + W PP ++   GI         T+  +      T+    +  ++GL  +M YT ++ A   +G+GP
Sbjct:  533 TKEIMGLTPYTVYKVAVAAKSDK-GVGPMSFVLTARTDEDRPSDAPQNIQGRSRDSTTLEISWDPPRPEHRNGLITHFTIKYRAKGQRGA-KYLTVDATKTSVVLHNLDKFTNYFIWVQASTKQGDGPFSDKHTVSTAEDVPNGAPRDVRIRVHNSTTMTVKWNPPTTKQDGKILGYMVFYTRVDDQGNQLRPPAQPESKDSMSEENHKVHLTGLAPETTYQIEVAAYTIKGDGARSVTRLAKTMAQSPDPPFVYLERASGDPISDVTLAWRT-----SATGVIEYKVRYAKSVRRLRGRDQGNLKMKEIKFKSHTTKQKFQSLANG----------IWYLFNVSLRTKAGWSPETSRWIEIPPGPPSGPPLN-VRAVAVSSTSV---EVTWSAPDIWNRGGPILGYSVMYN---PAN-----KRGDVTV----KNVTSPNIFKVVLKRLKKFREYEVRVRAIGMLGMGPASEPFIDRTKEDGKCHCRDVRPRTVGSDWVILEWLPPRID--AGIDTP-----LTHADEVRVDALTADVQTFK-VQGLVPHMKYTVRLSASNAMGEGP 1059          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Nematostella
Match: EDO43854 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXI9])

HSP 1 Score: 593.964 bits (1530), Expect = 0.000e+0
Identity = 296/591 (50.08%), Postives = 391/591 (66.16%), Query Frame = 1
Query: 4447 IPSGHLADYIAALKTNDNAKFTEEYESIDPGHH-FTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            IP    A ++  +  + +  F+EEYE + P    FTW  S    NK KNRYAN++AYDHSRV+L+ L  +  SDYINANY DGY +  A+IA+QGPLPETF+ FWRMVWE   A+IVM+T+LEER R KCDQYWP RG+  Y    ++ N  ET  ++YY +R F     L S     +E R V  + +T WPDHGVP    PLL  ++ V S  P  +GP++VHCSAGVGRTG +I LDS L +   E  +DV+G V ++R +RN MVQTE QYVFI+DAL+EA +CG TEV    L + + +L++  P +G       +T M+LEF+ L+     P QF +A L  N  KNR  NILPYE  RV L     + GSDYINASFIDG    KAYIATQ P+  T  DFWRMLW+  S+++VML++  E G+ KC +YWP++ S  + +I+VE   E     ++LR+F + H++ E  +R +RQFQ  DW + G+P SG  LID IGQV K ++Q G    ITVHCS GVGRTGVF A+SI+++R+++EG +D+FQTV+ LR+QRP MVQT+DQY+FCY T  EYL SFD +
Sbjct:    2 IPVEAFAMHVRRMHMDGDIGFSEEYEMVQPNDETFTWHHSLHPANKYKNRYANIVAYDHSRVLLTPLEGVLESDYINANYIDGYNRSGAFIASQGPLPETFDDFWRMVWEQGSAIIVMLTQLEERGRRKCDQYWPDRGTRNYGALRVTAN--ETFHMSYYVLRTF-----LVSHMQEEEEPRQVRQYHYTSWPDHGVPAHPAPLLSMVRTVSSANPPTAGPMIVHCSAGVGRTGTFITLDSMLQRAAQEGTIDVFGFVRQMRNKRNLMVQTESQYVFIHDALVEAVICGVTEVDANKLASRIRELREVDPNIG-------TTYMDLEFERLTRDERHPTQFKSAMLSCNAAKNRYANILPYERTRVALHMRPGEVGSDYINASFIDGNHRLKAYIATQAPVPRTFEDFWRMLWEQESAVIVMLTREEEAGKLKCHRYWPSDGSRLYDKILVELTEELTYSDYVLRQFSLTHTE-EKSSRIVRQFQCTDWPDSGLPESGVGLIDLIGQVEKWQQQSGNTC-ITVHCSGGVGRTGVFCAVSILIERVKAEGLIDVFQTVQHLRLQRPAMVQTKDQYEFCYTTIQEYLESFDLY 576          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Nematostella
Match: EDO45382 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT25])

HSP 1 Score: 563.918 bits (1452), Expect = 0.000e+0
Identity = 281/591 (47.55%), Postives = 384/591 (64.97%), Query Frame = 1
Query: 4447 IPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSC-CPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            +P     +++  L  N    F++EY +       T   S  + N+ KNRY N+ A+DH RV+L  +   P SDYINANY DGYRKQ  YIA QGPLPET   FWRMVWE    +IVM+T  EER R+KC QYWP+ GS+ Y    + +N + TVEL+ YT+R F + +      +GS E R V  + +T WPDHGVP++   +L F+++  +     D GP+VVHCSAGVGRTG Y+V+D+QL +IQ E  VDVY  V  LR QRN MVQ E+QYV I+D LLEA  CG+TE+  R L   + +L +P    G        T M+ EF+ LS     P +F +ANLP N+ KNR  N+LPY++ RV L      +GSDYINA++IDGY S+KA+IATQ P+ +TI DFWRM+W+ +   +VMLSQ  E G+ K  +YWP ++  + G ++VE + +     +I+REF+V ++  E+ +R +RQ+QF  W + G P SG  LID IGQV + +++ G +    VHCSAGVGRTGVF A+SI+++R+++E  VD+FQTV+ LR QRP MVQT++QY+FCY T  EYL SFD +
Sbjct:    1 MPVDEFEEHVRRLHANGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGV--IHVNMMSTVELSDYTIRSFGVKR------SGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMRPSTDTG-------QTEMDAEFQRLSRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNT-KESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQ-LTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDPY 574          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Nematostella
Match: EDO48187 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK45])

HSP 1 Score: 533.872 bits (1374), Expect = 1.564e-170
Identity = 271/583 (46.48%), Postives = 366/583 (62.78%), Query Frame = 1
Query: 4471 YIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGES---LIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFD 6210
            ++A ++ + +  FT EYE I    H T   S   +N+ KNRY N++AYDHSRV L    D PGSDYINAN+  GYR+ NAYIA QGPL ET   FWRMVWE     I+M+T L+ER R KC QYWP+RGS +Y +  ++++ +   EL  Y +R  S+ ++      G  + R V  F FT WPDHGVP +   LL F++      P  +GP+VVHCSAGVGRTG +IV+D  L QI  EK VD+ G VS LR  RN MVQTE+QY+FI+DALL+A + G TE S   L +H+ +L++  P  G TP       M  EF+ LS         N A  P N+ KNR  N+LPY+  RV L      +GSDYINA++IDGY +++ +IATQ P+  TI DFWRM+W+ N   +V L+Q  E  + K  +YWP ++  TFG ++VE   +      ++R F++ +++    +R +RQF +  W E+     G S   LID IGQV   + + G+  PI VHCSAGVGRTGVF A+SI+++R+++E  VD+FQTV+ LR QRP MVQT+ QY FCY   LEYL+SF+
Sbjct:    9 HVARMRRSGDLFFTTEYERIPVPEHVTATHSLDPVNQHKNRYINIVAYDHSRVKLQDFEDEPGSDYINANFLPGYRRDNAYIAAQGPLAETCRDFWRMVWEQNSRTIIMLTNLKERCRDKCAQYWPSRGSLSYEDITVTLDSV--TELTPYIVRTLSVQRE------GCDDVRQVKQFHFTSWPDHGVPTSVCNLLAFVRDSTRADPPGAGPMVVHCSAGVGRTGTFIVIDVMLQQIHEEKTVDILGFVSTLRRHRNLMVQTEQQYIFIHDALLDAIISGETETSASDLRSHIRRLQEQDPESGYTP-------MFTEFQKLSRCINSSLSLNAATHPVNKRKNRYANVLPYDVTRVRLSMQVGVEGSDYINANYIDGYMAKRTFIATQAPIPETIPDFWRMVWEQNCCTIVTLAQEVEQAKAKMHRYWPGKQPITFGSLVVEMQDKVKSGHLVVRIFKLTNTEVSA-SRDVRQFHYTSWTEENPLEDGLSRCQLIDLIGQVQYWQAESGRH-PIIVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKGQYDFCYQVVLEYLASFE 574          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Nematostella
Match: EDO45081 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTS6])

HSP 1 Score: 523.857 bits (1348), Expect = 4.602e-166
Identity = 273/636 (42.92%), Postives = 379/636 (59.59%), Query Frame = 1
Query: 4444 PIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAY--------------DHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQ------------------------------YWPTERS-ATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQF 6216
            PIP   LA+Y     +  N  F EE+  I    +F+W  S  E NKPKNRY N++A               DH+RV +S L+ IPGSDYINAN+ DGY  +N +IATQGP+  TF+ FWRMVWE  C+ IVM+T + ER ++KC +YWP+   E Y    L +  LE  EL++Y +RKF +     ++ +     R++  + +T WPDHGVP  A  LL FI+R+R+    D+GPIVVHCSAGVGRTG YIVLD+ L Q+  E  VD++G VS  R QRN MVQTE QY+FI+DAL+EA+ CGNTE  ++ LH  +  L+   P  G        T +  EFK+L    +    F++A++PEN+ KNR + +LPY+  RV L P     GSDYINASFID Y+ ++A++ATQ PL  TI DFWRMLW++ S  VVML++  E  + +  Q                              Y P +     +G ++VE   E     +I R+ ++ ++ S +  R +  FQ+ DW E GVP+ G+ +ID +  + + ++Q G  GPITVHCS G GRTG F A+SI L+R++ + T+D+FQTVR LR QRP MVQT +QY+FCY     ++ +F  +
Sbjct:    1 PIPVNKLAEYCQIHHSTGNKSFKEEFMCIRTPGNFSWDHSLKEENKPKNRYQNIVACKLFRLTNPCVNSVDDHTRVAISELDGIPGSDYINANFIDGYNHRNKFIATQGPVSNTFDDFWRMVWEHGCSCIVMVTNIVERGKLKCQKYWPSANPEEYGR--LVVTPLEEEELSHYVIRKFCIE---IANSDVESPAREIVQYHYTAWPDHGVPTHATSLLAFIRRIRNSVSRDAGPIVVHCSAGVGRTGTYIVLDAMLDQMSKEGAVDIFGFVSHTRLQRNMMVQTEAQYIFIHDALMEAAKCGNTEFKVQDLHDRIKALQSRDPDSG-------ETYIAKEFKNLDIGDSDVETFDSASMPENKSKNRFL-VLPYDRTRVKLWPYPGVLGSDYINASFIDSYQQREAFLATQAPLETTINDFWRMLWEYESYTVVMLNKDSENIKVRLKQTPGKTEIIIVQQRFFFLLISPKHVLYQGQSYLPDKGEFVVYGLLMVEVESEERQEGYIKRQLKISNTKS-SEVRNVFHFQYEDWPEDGVPQDGKLVIDMLKHIARAQQQTGN-GPITVHCSDGSGRTGTFCAISIALERVKLDATIDMFQTVRNLRTQRPIMVQTPEQYKFCYEVVRHFVEAFSDY 621          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Medaka
Match: PTPRD (receptor-type tyrosine-protein phosphatase delta [Source:NCBI gene;Acc:101165843])

HSP 1 Score: 869.766 bits (2246), Expect = 0.000e+0
Identity = 407/623 (65.33%), Postives = 483/623 (77.53%), Query Frame = 1
Query: 4354 VPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            +PL H     TD     + NF+   +  HPPIP   LAD++  LK NDN KF++EYESIDP   FTW  SNLE+NKPKNRYANVIAYDHSR++LS ++ IPGSDYINANY DGYRKQNAYIATQGPLPETF  FWRM+WE R A++VMMTKLEER RVKCDQYWPTRG+E Y    + ++ L+TVELA Y +R FSL K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L + +HEK VD+YG V+ +RAQRNYMVQTE+QYVFI+DALLEA  CG TEV  R+L+A++ KL Q           +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY   LEYL SFD + +
Sbjct: 1319 MPLHHP----TDPVELRRLNFQTPGMANHPPIPISELADHLERLKANDNLKFSQEYESIDPAQQFTWEHSNLEVNKPKNRYANVIAYDHSRILLSAIDGIPGSDYINANYIDGYRKQNAYIATQGPLPETFGEFWRMIWEQRSAVVVMMTKLEERSRVKCDQYWPTRGTETYGL--IQVSLLDTVELATYCVRTFSLFK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERNKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVNCGTTEVPARNLYAYIQKLTQ-------IEGGENVTGMELEFKRLANTKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFDHYAT 1921          

HSP 2 Score: 271.166 bits (692), Expect = 1.859e-72
Identity = 287/1113 (25.79%), Postives = 483/1113 (43.40%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQH-VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGI--DVRTLSPTS--IAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRH-NLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKN----TTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWE--LSHTNNIKVVGFKIYYCLQTIPKDIESCNT----LDVGPVTMVTLGNVQYNSDYQV---GIKSKGIDNRYGLISNIATAKISELPVIRDLSV-SSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKP 3471
            K +  P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + LP GFP   +     V +  +   M C   G      +WFKD  P++ S    R   LRSG++  ++  + D G YEC A N  G+  S    L +R   + P++   P D E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +       D+     K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS++I  +T E  PS+ P+ V     + T+  ++W  P EANG+I  Y VYY+ +    +N W+K      + V I  L  N TY+IKV A  S G GP+S    II + GVP QP +F+G   + TS+ L W+    PS+    + V  Y++I  K      +KEE+       T Y + +L P T Y   LAAR++HGVG + T  +  E      P G   +V+  SP+S  I + WR       +  I+ + +      S    +  +    QI ++P ++       +Y++ +LE    Y++ + +    G     +  +++T     VPS PP  + +  +   +          + W  P+    HG IR Y++ +  +V  +   + + +  L      +    T +      L     Y  +VAA  T   G   K   ++T  + P+   + +  T +   +  + W PP V   +G L  Y++    +G K+    T I      N Y   E + +   YTF++ A  KVG G  +         +    P NI+A     + I+V+W+  L    N K+V + + Y      KDI S  +        P + V L  ++ ++ Y +      SKG    Y       T  + +    ++  V +++K      S+ + W+ P T++    F +  +   S   +    +K  +  +P
Sbjct:   41 KFLRTPNDQTGVQGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNTVGEISASTRLTVLREDQ-LPPGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELTDVQQSANYTCVAMSTLGVIEAVAQITVKALPKAPGIPVVTERTATSITLTWDSGNPE---PVTYYIIQHKSKYSDDL---YKEINGV-------ATTRYSVGGLSPYSDYEFRVVAVNN-IGRGPPSESIEAKTAEQAPSTAPRHVRGHMMSATTAVIQWDEPEEANGQIMGYRVYYTMDPTQHVNIWEKQIVRGSNFVTIHGLIPNKTYNIKVLAYTSVGDGPLSPDLQIIAKTGVPSQPTDFKGEAKSETSVLLSWN---TPSQTGQENQVTGYELIYRKR----DDKEEKQISFEPTTTYLLKDLKPFTTYTFRLAARSKHGVG-AYTSEISAETPQTPEPAGPPEEVKCSSPSSTKILVSWRAPPVELRNGIITQYTV------SYAPTEGEDTAARQISNIPPESS------QYLLENLEKWTEYRVTVTAHTDVGAGPESLPHLIRTE--EDVPSGPPRKVEVEAVNSSS--------IKVIWRSPVPTKQHGQIRGYQVHYVRMVNGEPTGQPVIKDILIDDAQWEFEDSTEHEMIITGLMAETTYSVTVAAYTTKGDGARSKPKLITTTGAVPEKPRLMVSTTNM--GTALLQWHPPAVT--HGPLQGYRL---RFGRKDVDPLTVIEFQERDNHYTTSE-IHKGASYTFRLSARNKVGFGEETVKEITTNEDVPSGYPQNIKAEGATTSTIQVSWQPVLLAERNGKIVKYALQY------KDINSPRSPSELFITAPESTVVLDGLRPDTTYDIKMCAFTSKG-SGPYSPSVQFRTQPVDQAVFAKNFHVRAAMKS-----SVLLTWEIPDTYNPAQPFTILYDKGQSVEVDGRLTQKLITGLQP 1085          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Medaka
Match: PTPRD (receptor-type tyrosine-protein phosphatase delta [Source:NCBI gene;Acc:101165843])

HSP 1 Score: 868.611 bits (2243), Expect = 0.000e+0
Identity = 407/623 (65.33%), Postives = 483/623 (77.53%), Query Frame = 1
Query: 4354 VPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            +PL H     TD     + NF+   +  HPPIP   LAD++  LK NDN KF++EYESIDP   FTW  SNLE+NKPKNRYANVIAYDHSR++LS ++ IPGSDYINANY DGYRKQNAYIATQGPLPETF  FWRM+WE R A++VMMTKLEER RVKCDQYWPTRG+E Y    + ++ L+TVELA Y +R FSL K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L + +HEK VD+YG V+ +RAQRNYMVQTE+QYVFI+DALLEA  CG TEV  R+L+A++ KL Q           +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY   LEYL SFD + +
Sbjct: 1180 MPLHHP----TDPVELRRLNFQTPGMANHPPIPISELADHLERLKANDNLKFSQEYESIDPAQQFTWEHSNLEVNKPKNRYANVIAYDHSRILLSAIDGIPGSDYINANYIDGYRKQNAYIATQGPLPETFGEFWRMIWEQRSAVVVMMTKLEERSRVKCDQYWPTRGTETYGL--IQVSLLDTVELATYCVRTFSLFK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERNKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVNCGTTEVPARNLYAYIQKLTQ-------IEGGENVTGMELEFKRLANTKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFDHYAT 1782          

HSP 2 Score: 328.176 bits (840), Expect = 3.905e-90
Identity = 278/972 (28.60%), Postives = 444/972 (45.68%), Query Frame = 1
Query:  235 PRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQH-VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNSPIGIDVRTLSPTS--IAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNL--VGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGL-KNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNN 3072
            P     K +  P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + LP GFP   +     V +  +   M C   G      +WFKD  P++ S    R   LRSG++  ++  + D G YEC A N  G+  S    L +R   + P++   P D E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +       D+     K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS++I  +T E  PS+ P+ V     + T+  ++W  P EANG+I  Y VYY+ +    +N W+K      + V I  L  N TY+IKV A  S G GP+S    II + GVP QP +F+G   + TS+ L W+    PS+    + V  Y++I  K      +KEE+       T Y + +L P T Y   LAAR++HGVG  ++ ++  T    P  P   +V+  SP+S  I + WR       +  I+ + +      S    +  +    QI ++P ++       +Y++ +LE    Y++ + +   VG+   S P +      R    VP  P   RL  +   T  G  LL     W PP  +HG ++ YR+R     V P  +IE  +R +             +Y T   E+  G  Y F ++A N    G E    ++T E  P  YP +I   G T+ ++ +SWQP L+   NG +V Y + Y      ++ +    + P    +++GL+ +  Y  ++ AFT  G GP+S  V FRT  +      N       ++ + +TWE+  T N
Sbjct:   11 PNPAPPKFLRTPNDQTGVQGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNTVGEISASTRLTVLREDQ-LPPGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELTDVQQSANYTCVAMSTLGVIEAVAQITVKALPKAPGIPVVTERTATSITLTWDSGNPE---PVTYYIIQHKSKYSDDL---YKEINGV-------ATTRYSVGGLSPYSDYEFRVVAVNN-IGRGPPSESIEAKTAEQAPSTAPRHVRGHMMSATTAVIQWDEPEEANGQIMGYRVYYTMDPTQHVNIWEKQIVRGSNFVTIHGLIPNKTYNIKVLAYTSVGDGPLSPDLQIIAKTGVPSQPTDFKGEAKSETSVLLSWN---TPSQTGQENQVTGYELIYRKR----DDKEEKQISFEPTTTYLLKDLKPFTTYTFRLAARSKHGVGAYTSEISAETPQTQPAGPPE-EVKCSSPSSTKILVSWRAPPVELRNGIITQYTV------SYAPTEGEDTAARQISNIPPESS------QYLLENLEKWTEYRVTVTAHTDVGAGPESLPHLI-----RTEEDVPEKP---RL--MVSTTNMGTALL----QWHPPAVTHGPLQGYRLRFGRKDVDPLTVIEFQERDN-------------HYTT--SEIHKGASYTFRLSARNKVGFGEETVKEITTNEDVPSGYPQNIKAEGATTSTIQVSWQPVLLAERNGKIVKYALQYKDINSPRSPSELFITAPESTVVLDGLRPDTTYDIKMCAFTSKGSGPYSPSVQFRTQPVDQVFAKNFHVRAAMKSSVLLTWEIPDTYN 915          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Medaka
Match: PTPRD (receptor-type tyrosine-protein phosphatase delta [Source:NCBI gene;Acc:101165843])

HSP 1 Score: 866.685 bits (2238), Expect = 0.000e+0
Identity = 403/609 (66.17%), Postives = 477/609 (78.33%), Query Frame = 1
Query: 4396 SSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            SS   N   + +  HPPIP   LAD++  LK NDN KF++EYESIDP   FTW  SNLE+NKPKNRYANVIAYDHSR++LS ++ IPGSDYINANY DGYRKQNAYIATQGPLPETF  FWRM+WE R A++VMMTKLEER RVKCDQYWPTRG+E Y    + ++ L+TVELA Y +R FSL K      NGS E R+V  FQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+ L + +HEK VD+YG V+ +RAQRNYMVQTE+QYVFI+DALLEA  CG TEV  R+L+A++ KL Q           +  TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE+ RVCLQPIR  +GSDYINASFIDGYR QKAYIATQGPLA T  DFWRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPI+VHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP MVQTEDQYQFCY   LEYL SFD + +
Sbjct: 1343 SSHPRNLHLSSMANHPPIPISELADHLERLKANDNLKFSQEYESIDPAQQFTWEHSNLEVNKPKNRYANVIAYDHSRILLSAIDGIPGSDYINANYIDGYRKQNAYIATQGPLPETFGEFWRMIWEQRSAVVVMMTKLEERSRVKCDQYWPTRGTETYGL--IQVSLLDTVELATYCVRTFSLFK------NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERNKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVNCGTTEVPARNLYAYIQKLTQ-------IEGGENVTGMELEFKRLANTKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFDHYAT 1935          

HSP 2 Score: 270.781 bits (691), Expect = 2.452e-72
Identity = 290/1116 (25.99%), Postives = 484/1116 (43.37%), Query Frame = 1
Query:  253 KIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQH-VRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGI--DVRTLSPTS--IAIRWRKGMDNEES--ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWS---VGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYRIRH-NLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN-VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKN----TTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWE--LSHTNNIKVVGFKIYYCLQTIPKDIESCNT----LDVGPVTMVTLGNVQYNSDYQV---GIKSKGIDNRYGLISNIATAKISELPVIRDLSV-SSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKP 3471
            K +  P  QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C+  N   E   +  L V    + LP GFP   +     V +  +   M C   G      +WFKD  P++ S    R   LRSG++  ++  + D G YEC A N  G+  S    L +R   + P++   P D E+ PG  VN+TC A G+P P ++W+   +   P +D+    ++L LTD+ + A+Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +       D+     K+I  +           Y+V  L PY+ Y  +V+A +  +G   PS++I  +T E  PS+ P+ V     + T+  ++W  P EANG+I  Y VYY+ +    +N W+K      + V I  L  N TY+IKV A  S G GP+S    II + GVP QP +F+G   + TS+ L W+    PS+    + V  Y++I  K      +KEE+       T Y + +L P T Y   LAAR++HGVG + T  +  E      P G   +V+  SP+S  I + WR       +  I+ + +      S    +  +    QI ++P ++       +Y++ +LE    Y++ + +   VG+   S P +      R    VPS PP  + +  +   +          + W  P+    HG IR Y++ +  +V  +   + + +  L      +    T +      L     Y  +VAA  T   G   K   ++T  + P+   + +  T +   +  + W PP V   +G L  Y++    +G K+    T I      N Y   E + +   YTF++ A  KVG G  +         +    P NI+A     + I+V+W+  L    N K+V + + Y      KDI S  +        P + V L  ++ ++ Y +      SKG    Y       T  + +    ++  V +++K      S+ + W+ P T++    F +  +   S   +    +K  +  +P
Sbjct:   41 KFLRTPNDQTGVQGGVASFICQATGDP--RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECVASNTVGEISASTRLTVLREDQ-LPPGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELTDVQQSANYTCVAMSTLGVIEAVAQITVKALPKAPGIPVVTERTATSITLTWDSGNPE---PVTYYIIQHKSKYSDDL---YKEINGV-------ATTRYSVGGLSPYSDYEFRVVAVNN-IGRGPPSESIEAKTAEQAPSTAPRHVRGHMMSATTAVIQWDEPEEANGQIMGYRVYYTMDPTQHVNIWEKQIVRGSNFVTIHGLIPNKTYNIKVLAYTSVGDGPLSPDLQIIAKTGVPSQPTDFKGEAKSETSVLLSWN---TPSQTGQENQVTGYELIYRKR----DDKEEKQISFEPTTTYLLKDLKPFTTYTFRLAARSKHGVG-AYTSEISAETPQTPEPAGPPEEVKCSSPSSTKILVSWRAPPVELRNGIITQYTV------SYAPTEGEDTAARQISNIPPESS------QYLLENLEKWTEYRVTVTAHTDVGAGPESLPHLI-----RTEEDVPSGPPRKVEVEAVNSSS--------IKVIWRSPVPTKQHGQIRGYQVHYVRMVNGEPTGQPVIKDILIDDAQWEFEDSTEHEMIITGLMAETTYSVTVAAYTTKGDGARSKPKLITTTGAVPEKPRLMVSTTNMG--TALLQWHPPAVT--HGPLQGYRL---RFGRKDVDPLTVIEFQERDNHYTTSE-IHKGASYTFRLSARNKVGFGEETVKEITTNEDVPSGYPQNIKAEGATTSTIQVSWQPVLLAERNGKIVKYALQY------KDINSPRSPSELFITAPESTVVLDGLRPDTTYDIKMCAFTSKG-SGPYSPSVQFRTQPVDQAVFAKNFHVRAAMKS-----SVLLTWEIPDTYNPAQPFTILYDKGQSVEVDGRLTQKLITGLQP 1085          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Medaka
Match: PTPRD (receptor-type tyrosine-protein phosphatase delta [Source:NCBI gene;Acc:101165944])

HSP 1 Score: 858.981 bits (2218), Expect = 0.000e+0
Identity = 395/604 (65.40%), Postives = 475/604 (78.64%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPP+P   L D+I  LK NDN KF++EYES+DPG  FTW  SNLE+NKPKNRYANVIAYDHSRVVLS++  +PGSDYINANY DGYR+QNAYIATQG LPETF  FWRMVWE   A I+MMTKLEE+ RVKCDQYWPTRG+E Y    + +  L+TVELA Y++R F+L K      NGS E R+V HFQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+   +I+HEK +DVYG V+ +R+QRNYMVQTE+QY+FI+DA+LEA  CGNTEV  R+L++++ +L Q  P   V       TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE  RVCLQPIR  +GSDYINASFIDGYR Q+AYIATQGPLA T  D+WRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP  VQTEDQYQFCY  +LEYL SFD + +
Sbjct:  910 NFQTPGMASHPPVPISELTDHIERLKANDNLKFSQEYESVDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLSSIEGVPGSDYINANYIDGYRRQNAYIATQGALPETFGDFWRMVWEQHSANIIMMTKLEEKSRVKCDQYWPTRGTETYGL--IQVTLLDTVELATYSVRTFALYKV-----NGSNEKREVRHFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMTERIKHEKTIDVYGHVTLMRSQRNYMVQTEDQYIFIHDAVLEAVTCGNTEVPARNLYSYIQRLTQIEPGENV-------TGMELEFKRLASAKAHTSRFVSANLPCNKFKNRLVNIMPYETTRVCLQPIRGVEGSDYINASFIDGYRQQRAYIATQGPLAETTEDYWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPATVQTEDQYQFCYRASLEYLGSFDHYAT 1498          

HSP 2 Score: 246.514 bits (628), Expect = 3.648e-65
Identity = 178/612 (29.08%), Postives = 285/612 (46.57%), Query Frame = 1
Query:  214 VMKEHLNPR-KGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYV---------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSET-TRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHI--PTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRT 1992
            ++    NP  + + +    P+ QT + G  A F CQ  G+P     +++N   K V             SG +LRI  ++    + +  +C   N + E   +  L+V    + LP GFP   +     V +  +   M C   G    + +WFKD  P++ S    R   LRSG++  +   + D G YEC A N  G+  S    L +R   + P++   P D E+ PG  +N+TC A G+P P ++W+   +   P +D+    ++L LTD+ +  +Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +       ++     K+I  I           Y+V  L PY+ Y  +V AF+ T+G   PS+ +   T E  PSSPP+ V     + T+  + W  P E NG++  Y VYY+ +   P+NQW K    +   + I DL  N TY+I+V A  S G GP+S+   II + GVP QP  F+G   + TSI L W  P                 I+G  +    + + EE+       T Y +  L P + Y   LAA++++G+G  +N +++ T
Sbjct:   11 ILASFFNPSDRTSPRFTRTPEDQTGVQGGVASFVCQAAGDP--QPKIMWNKKGKRVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAI-YECHASNSAGEITASTRLSVLREDQ-LPAGFPTIDMGPQLKVVERSRTATMLCAASGNPDPEISWFKDFLPVNTSSNNGRIKQLRSGALQIEMSEESDQGKYECVATNSDGTRYSTPANLYVRVRRVPPRFSIPPADSEIMPGGNINITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELTDVRQSNNYTCVAMSTLGVIEAMAQITVKALPKAPGMPMVTERTATSITLTWDSGNPE---PVSYYVIQYRGKGSEDP---FKEIDGI-------ATTRYSVGGLSPYSHYDFRVAAFN-TIGQGPPSEVVEARTAEQAPSSPPRQVIGRMLSATTAMIHWDEPEEPNGQVVGYRVYYTSDNMLPVNQWDKQMVRSTSFITIQDLTPNKTYYIRVLAFTSVGDGPLSQDLQIIAKTGVPSQPSEFKGEAKSETSILLSWVAPS--------TQGGPESQITGYELVYRRVNDSEEKKVTFEPTTSYLLKNLKPFSTYTFQLAAKSKNGIGAYTNEVSIGT 596          

HSP 3 Score: 62.3882 bits (150), Expect = 6.004e-9
Identity = 61/217 (28.11%), Postives = 95/217 (43.78%), Query Frame = 1
Query: 2611 YEFSVAAMNTADIGLEVKL-NVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGL------KNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNN---IKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDY--QVGIKSK 3225
            Y+F VAA NT   G   ++    T E AP S P  +    +++ +  I W  P  E  NG +V Y+V Y +  +          +R+TS    +  I+ L  N  Y  +V AFT VG GP S D+       +P  P   +    +E  I ++W    T      ++ G+++ Y  + +    E   T +  P T   L N++  S Y  Q+  KSK
Sbjct:  376 YDFRVAAFNTIGQGPPSEVVEARTAEQAPSSPPRQVIGRMLSATTAMIHWDEP--EEPNGQVVGYRVYYTSDNMLPVNQWDKQMVRSTS----FITIQDLTPNKTYYIRVLAFTSVGDGPLSQDLQIIAKTGVPSQPSEFKGEAKSETSILLSWVAPSTQGGPESQITGYELVY--RRVNDSEEKKVTFE--PTTSYLLKNLKPFSTYTFQLAAKSK 582          

HSP 4 Score: 53.9138 bits (128), Expect = 2.714e-6
Identity = 83/372 (22.31%), Postives = 140/372 (37.63%), Query Frame = 1
Query: 1960 VGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIG-LEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENH-NGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTN 3069
            +GV   M   T   +P +P    V   + TSI + W  G  N E +S +   VI+ +   + D            P K  +      Y +  L    +Y   + +  + G   P   ++V+ R     PS P        RQ     L+   A I WD P   +G +  YR+ +                L V  ++K +  +       +L   K Y   V A  +   G L   L +  +   P S P        +  S+ +SW  P  +      +  Y++ Y      +   + T  P    L++ L+    YTFQ+ A +K G G ++++V+  T   L      ++AS   +N I ++WE+   N
Sbjct:  295 LGVIEAMAQITVKALPKAPGMPMVTERTATSITLTWDSG--NPEPVSYY---VIQYRGKGSED------------PFKEIDGIATTRYSVGGLSPYSHYDFRVAAFNTIGQGPPS--EVVEARTAEQAPSSPP-------RQVIGRMLSATTAMIHWDEPEEPNGQVVGYRVYYT-----------SDNMLPVNQWDKQMVRSTSFITIQDLTPNKTYYIRVLAFTSVGDGPLSQDLQIIAKTGVP-SQPSEFKGEAKSETSILLSWVAPSTQGGPESQITGYELVYRRVN-DSEEKKVTFEPTTSYLLKNLKPFSTYTFQLAAKSKNGIGAYTNEVSIGTPQTLFATNFRVKASM--KNSILLSWEIRDKN 625          
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Medaka
Match: PTPRD (receptor-type tyrosine-protein phosphatase delta [Source:NCBI gene;Acc:101165944])

HSP 1 Score: 855.129 bits (2208), Expect = 0.000e+0
Identity = 394/604 (65.23%), Postives = 475/604 (78.64%), Query Frame = 1
Query: 4411 NFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            NF+   +  HPP+P   L D+I  LK NDN KF++EYES+DPG  FTW  SNLE+NKPKNRYANVIAYDHSRVVLS++  +PGSDYINANY DGYR+QNAYIATQG LPETF  FWRMVWE   A I+MMTKLEE+ RVKCDQYWPTRG+E Y    + +  L+TVELA Y++R F+L K      +GS E R+V HFQFT WPDHGVP+   P L F++RV++C P D+GP+VVHCSAGVGRTG +IV+D+   +I+HEK +DVYG V+ +R+QRNYMVQTE+QY+FI+DA+LEA  CGNTEV  R+L++++ +L Q  P   V       TGMELEFK L+       +F +ANLP N+ KNRL+NI+PYE  RVCLQPIR  +GSDYINASFIDGYR Q+AYIATQGPLA T  D+WRMLW+HNS+IVVML++LREMGREKC QYWP ERSA +   +V+PM EYNMP +ILREF+V  +  +  +RT+RQFQF DW EQGVP+SGE  IDFIGQVHKTKEQFGQ+GPITVHCSAGVGRTGVF+ LSIVL+RMR EG VD+FQTV++LR QRP  VQTEDQYQFCY  +LEYL SFD + +
Sbjct: 1230 NFQTPGMASHPPVPISELTDHIERLKANDNLKFSQEYESVDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLSSIEGVPGSDYINANYIDGYRRQNAYIATQGALPETFGDFWRMVWEQHSANIIMMTKLEEKSRVKCDQYWPTRGTETYGL--IQVTLLDTVELATYSVRTFALYK------SGSNEKREVRHFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMTERIKHEKTIDVYGHVTLMRSQRNYMVQTEDQYIFIHDAVLEAVTCGNTEVPARNLYSYIQRLTQIEPGENV-------TGMELEFKRLASAKAHTSRFVSANLPCNKFKNRLVNIMPYETTRVCLQPIRGVEGSDYINASFIDGYRQQRAYIATQGPLAETTEDYWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDA-RDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPATVQTEDQYQFCYRASLEYLGSFDHYAT 1817          

HSP 2 Score: 237.654 bits (605), Expect = 2.595e-62
Identity = 221/839 (26.34%), Postives = 359/839 (42.79%), Query Frame = 1
Query:  526 LPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSE--PRRTMLRS---------GSIFFDRLLKEDSGIYECRAINPVGSILSIKMKL------EIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWL--TQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQ-NPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSET-TRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHI--PTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGV-SNTMNVRTENRVPNS-PIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIE-TVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDPPI--NSHGTIRAYR---IRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQG 2946
            LP GFP   +     V +  +   M C   G    + +WFKD  P++ S    R   LRS         G++  +   + D G YEC A N  G+  S    L      E+R  P  P++   P D E+ PG  +N+TC A G+P P ++W+   +   P +D+    ++L LTD+ +  +Y C A +++GVI+   Q+ VK +PK P          T   ++W+  NPE   P   + +       ++     K+I  I           Y+V  L PY+ Y  +V AF+ T+G   PS+ +   T E  PSSPP+ V     + T+  + W  P E NG++  Y VYY+ +   P+NQW K    +   + I DL  N TY+I+V A  S G GP+S+   II + GVP QP  F+G   + TSI L W  P                 I+G  +    + + EE+       T Y +  L P + Y   LAA++++G+G  +N +++ T    P++ P  I   + S TSI + W            F+  +I   SI+ T    N+   +I  +P ++        Y++ +LE    Y I + +   +G     +  +++T     VPS PP  +    +              + W  P     HG IR Y+   +R N   PQ    S+K   +    +E       Y    G+L     Y  SV A      G   K  ++   + P      + +T   S +  + W PP   N    ++ Y++ +    +    +    T      ++ +Q+   Y F++ +  K+G G
Sbjct:   14 LPAGFPTIDMGPQLKVVERSRTATMLCAASGNPDPEISWFKDFLPVNTSSNNGRIKQLRSESFGGTPIRGALQIEMSEESDQGKYECVATNSDGTRYSTPANLYVRELREVRRVP--PRFSIPPADSEIMPGGNINITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELTDVRQSNNYTCVAMSTLGVIEAMAQITVKALPKAPGMPMVTERTATSITLTWDSGNPE---PVSYYVIQYRGKGSEDP---FKEIDGI-------ATTRYSVGGLSPYSHYDFRVAAFN-TIGQGPPSEVVEARTAEQAPSSPPRQVIGRMLSATTAMIHWDEPEEPNGQVVGYRVYYTSDNMLPVNQWDKQMVRSTSFITIQDLTPNKTYYIRVLAFTSVGDGPLSQDLQIIAKTGVPSQPSEFKGEAKSETSILLSWVAPS--------TQGGPESQITGYELVYRRVNDSEEKKVTFEPTTSYLLKNLKPFSTYTFQLAAKSKNGIGAYTNEVSIGTPQTPPSAPPQDISCTSPSSTSILVSW------APPPLEFRNGIITGYSIQYTTMEGNKTSKRIDGIPPESS------PYLLENLEKWTEYGITVRASTEAGEGPESLQLLIRTE--EDVPSGPPRGVEAETVNASA--------IRVKWRAPAPERQHGQIRGYQVHYVRMNYGEPQGQ-PSIKDILIDDSQWEYG-DSVEYEVILGDLKSDTAYSVSVGAYTAKGDGARSK-PITECTALPLPEKPRLMVTVSDSGTALLHWYPP--SNPPTPILGYRLTFGRVDVLPFVVVEFPTKETRYTVQDIQKGAKYEFRLCSHNKMGYG 801          

HSP 3 Score: 146.362 bits (368), Expect = 1.986e-34
Identity = 237/999 (23.72%), Postives = 398/999 (39.84%), Query Frame = 1
Query:  244 GAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLY----------NGMKKYV-------IPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTA---YLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKF-NWF---KDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQY-----HRPINDL----TDKESILLLTDITEPASYICRANN-SMGVIQHAVQVR-VKKIPKIP-VNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVT--DLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANG---KITDYNVYYSRNLQHPINQWQKSETTRQHVR---ITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQ--PHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIK-----ILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNSP-IGIDVRTLSPTSIAIRWRKGMDNEE--SISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQP-PLVENHNGILVNYQVAYFTYGLK-NTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTN 3069
            G   I + PQ + V    TA   C   GNP   +S             NG  K +        PI   L + + +    +    + +C+  N       T    Y+      + +P   PRF +         G N+ + C V  G P+ +  W    +D  P D     R +L    +         S  Y C A++ +G I ++  ++ ++  P  P     P   E R    + LT  + GNP P   ++ QY       P  ++    T + S+  L+  +     +   N    G     V+ R  ++ P  P   +    +  T A I W++  E +     + +       DN +        ++ W       T  +T  DL P   Y ++V+AF+ ++GD   S+ + I  K   PS P +     A + TSI + W  P    G   +IT Y + Y R     +N  ++ + T +      + +L   +TY  ++ A +  G G  +    I   P  PP   P +      +STSI + W+PP L           +  +I+G  I   T +  +       I P+ + Y +  L   T Y I++ A TE G G  S  + +RTE  VP+ P  G++  T++ ++I ++WR      +   I  +++  +++   E     +   + I     +  +  + YE I+ DL++   Y + + +  + G       D  +++P     + PL  +   +   ++SG  LL     W PP N    I  YR+    V             L   V E     T Y  +  ++  G  YEF + + N    G E    V+T E AP  YP +I +    + S++++W+  PL+E  NG +V Y V Y     + N +      P   A +EGL  + +Y  +V AFT VG GP+S  V FRT  L      N       +N I ++WE+   N
Sbjct:   17 GFPTIDMGPQLKVVERSRTATMLCAASGNPDPEISWFKDFLPVNTSSNNGRIKQLRSESFGGTPIRGALQIEMSE----ESDQGKYECVATNSDGTRYSTPANLYVRELREVRRVP---PRFSIPPADSEIMPGGNINITC-VAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELTDV-------RQSNNYTCVAMSTLGVIEAMA-QITVKALPKAPGM---PMVTE-RTATSITLTWDS-GNPEPVSYYVIQYRGKGSEDPFKEIDGIATTRYSVGGLSPYSHYDFRVAAFNTIGQGPPSEVVEARTAEQAPSSPPRQVIGRMLSATTAMIHWDEPEEPNGQVVGYRVYYTS---DNML-------PVNQWDKQMVRSTSFITIQDLTPNKTYYIRVLAFT-SVGDGPLSQDLQIIAKTGVPSQPSE-FKGEAKSETSILLSWVAPSTQGGPESQITGYELVYRR-----VNDSEEKKVTFEPTTSYLLKNLKPFSTYTFQLAAKSKNGIGAYTNEVSIGT-PQTPPSAPPQDISCTSPSSTSILVSWAPPPL---------EFRNGIITGYSIQYTTMEGNKTSKRIDGIPPESSPYLLENLEKWTEYGITVRASTEAGEGPESLQLLIRTEEDVPSGPPRGVEAETVNASAIRVKWRAPAPERQHGQIRGYQVHYVRMNYGEPQGQPSIKDILIDDSQWEYGDSVE-YEVILGDLKSDTAYSVSVGAYTAKG-------DGARSKPITECTALPLPEKPRLMVTVSDSGTALL----HWYPPSNPPTPILGYRLTFGRVD-----------VLPFVVVEFPTKETRYTVQ--DIQKGAKYEFRLCSHNKMGYGEEAVKEVTTPEDAPSGYPENIILEDAYATSLHLAWKSVPLIE-QNGKIVKYSVLYKDINSRGNASEVVVPAPGSSAKLEGLIADTVYDVRVCAFTAVGPGPYSPSVRFRTQRLDQVFATNFRVKASMKNSILLSWEIRDKN 941          
BLAST of Receptor type tyrosine protein phosphatase vs. Planmine SMEST
Match: SMESG000041927.1 (SMESG000041927.1)

HSP 1 Score: 4217.54 bits (10937), Expect = 0.000e+0
Identity = 2066/2074 (99.61%), Postives = 2069/2074 (99.76%), Query Frame = 1
Query:    1 MLLNFLWVSKILEIIFYVKIHVYVLYKISYFNICKCLVWNYPLVGYKWKTFLIIQIILSNQIVFAQWFRLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            MLLNFLWVSKILEIIFYVKIHVYVLYKISYFNICKCLVWNYPLVGYKWKTFLIIQIILSNQIVFAQWFRLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFK IKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECR INPVGSILS KMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYT+YSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTI+AYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPIS SPILVAEFSNDIFKKGSNISFWVGQDIWRSQY KPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTVSIIAIIIGLGVIALISIAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGT+DLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS
Sbjct:    1 MLLNFLWVSKILEIIFYVKIHVYVLYKISYFNICKCLVWNYPLVGYKWKTFLIIQIILSNQIVFAQWFRLQVMKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKSIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRVINPVGSILSSKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTKYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIKAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISDSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYSKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTVSIIAIIIGLGVIALISIAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTIDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 2074          
BLAST of Receptor type tyrosine protein phosphatase vs. Planmine SMEST
Match: SMESG000041927.1 (SMESG000041927.1)

HSP 1 Score: 4063.46 bits (10537), Expect = 0.000e+0
Identity = 1994/2002 (99.60%), Postives = 1997/2002 (99.75%), Query Frame = 1
Query:  217 MKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            MKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFK IKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECR INPVGSILS KMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYT+YSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTI+AYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPIS SPILVAEFSNDIFKKGSNISFWVGQDIWRSQY KPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTVSIIAIIIGLGVIALISIAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGT+DLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS
Sbjct:    1 MKEHLNPRKGAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKSIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRVINPVGSILSSKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTKYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIKAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISDSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYSKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTVSIIAIIIGLGVIALISIAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTIDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 2002          
BLAST of Receptor type tyrosine protein phosphatase vs. Planmine SMEST
Match: SMESG000041927.1 (SMESG000041927.1)

HSP 1 Score: 4047.28 bits (10495), Expect = 0.000e+0
Identity = 1985/1993 (99.60%), Postives = 1988/1993 (99.75%), Query Frame = 1
Query:  244 GAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            GAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFK IKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECR INPVGSILS KMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYT+YSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTI+AYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPIS SPILVAEFSNDIFKKGSNISFWVGQDIWRSQY KPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTVSIIAIIIGLGVIALISIAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGT+DLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS
Sbjct:   22 GAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKSIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRVINPVGSILSSKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTKYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIKAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISDSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYSKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTVSIIAIIIGLGVIALISIAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTIDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 2014          
BLAST of Receptor type tyrosine protein phosphatase vs. Planmine SMEST
Match: SMESG000041927.1 (SMESG000041927.1)

HSP 1 Score: 4042.27 bits (10482), Expect = 0.000e+0
Identity = 1985/1993 (99.60%), Postives = 1988/1993 (99.75%), Query Frame = 1
Query:  244 GAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 6222
            GAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFK IKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECR INPVGSILS KMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYT+YSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTI+AYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPIS SPILVAEFSNDIFKKGSNISFWVGQDIWRSQY KPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTVSIIAIIIGLGVIALISIAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGT+DLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS
Sbjct:   35 GAAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKSIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRVINPVGSILSSKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTKYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIKAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESLQSASKPISDSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYSKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTVSIIAIIIGLGVIALISIAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPSYVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTIDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFLS 2027          
BLAST of Receptor type tyrosine protein phosphatase vs. Planmine SMEST
Match: SMESG000068618.1 (SMESG000068618.1)

HSP 1 Score: 1165.98 bits (3015), Expect = 0.000e+0
Identity = 717/1951 (36.75%), Postives = 1060/1951 (54.33%), Query Frame = 1
Query:  250 AKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSLLYNGM-------KKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKMNCDVEGGLPIKFNWFKD-NAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQY---------HRPINDLTDKESILLLTDITEPASYICRANNSMGVIQHAVQVRVKKIPKIPVNITCLNIGPTDAQISW---EQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPP-----DNKNITYNVTDLRPYTRYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSXXXXXXXXXXXXXISGKHIPTLTNKEEEIKIL-----PDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQ-LRQKTESGLTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTI-RTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNN------IKVVGFKIYYCLQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETG--EVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIEESIHTQKTNFSKYSFESL-QSASKPISYSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYP-KPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTE--ITSFANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTXXXXXXXXXXXXXXXXXXAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQ-AVSGP--PSYV---------------------PLSHSNGIVTDMDSSIKSNFKNTIVNK---------------------------HPPIPSGHLADYIAALKTNDNAKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPN---GSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMV 5808
            A I   P   T   G      C+  GNP   +    NG        +K +     G  LR   V++ +   V + CI  N    + K+A + V D + ++P GFP         +   G+  K+ C+V      K  W K+ +  +D +  R  ++ +GS+    + + D G YEC A N VG+++S    L+IR +P+TPQ +     +EV  G G NLTC A+G+P P + W  Q          +RP+ D     S + LTDITE  SY+C A N MG+I+   Q+ VKK P  P  ++   +  T A I W   + NP    P +S+TL+I D S  +  LGL+QI N++ +PP     ++K +++ +T+L+ YT Y V+V+A S  +G+SDPS  I  +T ELPPSSPP  ++A A +  SI V W PP++ NG+I  Y +YY+  L   I+ W   E       + +L  N TY++KVNA N AG GPVS+ FPI+V  GVPP P N RGA +++TSI ++W+ P +          +    + G  +    + +E+ K+      P +T Y +  L P   YHISLA +T+ GVGVS  +   T++ +P+ P  + ++ ++ TS  I W+  M   +++   K  +I+ +  E  + S    V   +V     N +++YE+I+N+L   + YKI + +    G  +P  F+I+KT     VPS P  +R+ Q ++  +  G   L   +AW+PP  SHG I  YR+  +L+GP   ++ LK     VK+Y    T T    E  ++G GK Y F V A+N+ + G   ++N +  E  P + P  ++I G    +V + W PP ++  NGI+  Y++ YF       T+  T +      +I  LQEN  Y F++RA  K G GPWS    +         P NIE   +N+ QIKV+W      N       +V GF +         D +      VGP T   +  + Y + Y + +++   D R    SNI T  + +     + ++  L C G+  S+++ W+KP  +  +  F + ++GY  +    G  ++EK K+     E  F ++   +   + ++ PN  YD+S++ +Y     S      + TSC TLM +PK + +P  + + + S  I LR+ R  E LG+I  YYLI+     T  T       E+  Q+ +     S  + A+F+  +F+  S + F +G     S  P +  ++ D + ++ +    K + K FLRAC+  E   +   +     CT S WS  F    S  IN     ++  VFT ++IA I  +  +  I I   CF+KR   K   + P   + + DP LKQ L+ Q  +SG   P Y                       L  ++G++T +++    +  N +  +                            PPIP   L   I  L+ NDN  F++EYESIDPG  FTW  SNLEIN+ KNRYANVIAYDHSR++L  +N + GSDYINANY DGY++ NAYIATQGPL  TF  FWRMVWE   A IVMMTKLEER R+KCDQYWP +G+E+YA+  +++   +T ELAYYT+R F ++   SS+ +    +K+ R++  +QFT WPDHGVPD  +PLLMF+KR+R+  P  S PI+VHCSAGVGRTGA+IV+D+ L +I+HE  VD++G VS +RAQRNYMVQTE+QYVF+++ +L+A    NTEVS++++  HV KL +       T   Q +TG+ELEF+ LS+      +  +ANLP NRLKNRL+NILPYE  R+CLQPIR  +GSDYINAS+IDGY++ KAYIATQ PL  TI DFWRM+W+HNS+I+VML++LREMGREKC +YWPTERS+ F   +V+PM+
Sbjct:   29 AMITEHPLDTTAQAGFFIFLICKAQGNPKPTVQFKINGKVQSNDSHRKIIRSFDFGASLR-QQVQMDNNNDV-VQCIAENHLGVDTKSATITVIDSNAEVPAGFPIITSGPIDVLSQFGKIAKIRCEVSADPSAKVTWIKNSHEKVDSNNERFQVVGTGSLTIKNVRETDGGSYECMATNKVGTVISQSGMLQIRQSPMTPQIVDFKSKIEVSTGQGANLTCNAEGSPIPLVHWEVQIGNPNSPNPENRPLGDEQPSSSTIHLTDITESGSYVCHAKNKMGLIKKEAQIIVKKKPMAPTLVSYSKVEATSAVIEWLPVKSNP----PIDSYTLLIKDTSNKDPHLGLRQIANLY-FPPQKLSSESKKVSFQITELKAYTNYEVQVVAVSNNIGNSDPSLPIRFQTLELPPSSPPTDLFAKAISPDSIKVTWKPPLQQNGRIKGYRLYYTERLWSAIDNWHIREVQDTPYYLNNLIHNATYYVKVNAYNLAGDGPVSDAFPILVVVGVPPVPQNLRGASLSTTSIQIMWTHPAM----------VDDHKLEGYELKYRLDGDEKGKMFKEHIEPYQTQYLIDNLKPGKAYHISLAGKTKFGVGVSAQLTETTKDEIPDKPEAVSIKVINSTSSKISWKGPM---KTLDQVKYYIIEWR--ELSNKSKNSKVFNVTVDINKSNPNNVYEHILNNLLPNKYYKIEVLAASRKGKGSPEKFEIIKTHGNFKVPSMPRELRMTQSVKIPSFKGPKRLAVYLAWNPPQISHGLILGYRVAISLIGPPEFVKELK----PVKIYRNVSTETYKSDEEAKIGPGKTYLFEVQALNSVNFGETARINYTIPEERPSAPPNKLEIQG-EKKTVTLKWHPPPIDYRNGIITKYKIQYFDMKEPVLTLKETETESKTTEMITNLQENTNYVFKIRAVNKEGDGPWSPGTPYYISSEFFPAPENIETKALNDYQIKVSWNFPEKANQVTDLLSQVNGFHVQVSTNRDFPDGKITFKKIVGPFTSTVMEKI-YPNHYFIRVQAIIRDKRIAEWSNIHTLTVFKSKYT-ERNIKGLNCIGQTNSIKVTWEKPDDYTEIKSFLIELSGYRKFRNIYGAYKIEKIKARTSRIEF-FGEEQSTYNYSIPNLEPNTNYDLSIKILY--SSISKLESISKTTSCVTLMEQPKSILSPMPVPLRKVSNEIILRLSRTNEILGMISHYYLIVSPIKETHVTPHDVNIDETFTQTKNLKAMNSRYVAAQFTPALFRSKSYVDFVLG-----SNSPIESFHSNDWIFLKRLPVKKKTNLKAFLRACVIPEGLTSDLKSIPVERCTSSEWSMTF----STDIN-----REIQVFTAAVIAGIGSIVFLVFICIGFACFLKRSHSK--ISRP---LGSTDPCLKQPLMMQPGLSGGNLPQYTNIVNIGNSSRHGYTDSLRTNSDLCATSGVMTPINNHQPLSVSNPMFEQRSLELKKISNTQAPDLVQNALSISNSVRPPIPVHRLESQINELRANDNFLFSQEYESIDPGQQFTWENSNLEINRAKNRYANVIAYDHSRILLQYINGVLGSDYINANYIDGYKRPNAYIATQGPLSNTFGDFWRMVWEQGTASIVMMTKLEERTRIKCDQYWPNKGTESYADGAITVTITDTKELAYYTIRTFIISANYSSNSSEFCSNKDKREIRQYQFTAWPDHGVPDNPMPLLMFLKRIRAGNPLSSRPIIVHCSAGVGRTGAFIVIDTTLERIRHEMTVDIFGQVSIMRAQRNYMVQTEDQYVFVHEVVLDAVRASNTEVSLQNISTHVQKLMR----ADCTTGTQRATGIELEFQKLSQFKPNNARCTSANLPVNRLKNRLVNILPYEFNRICLQPIRGCEGSDYINASYIDGYQNVKAYIATQAPLMETIEDFWRMIWEHNSTIIVMLTKLREMGREKCHRYWPTERSSRFQYFVVDPMM 1924          

HSP 2 Score: 210.69 bits (535), Expect = 4.615e-54
Identity = 108/250 (43.20%), Postives = 153/250 (61.20%), Query Frame = 1
Query: 5473 ANLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATF--GQIIV-----EPMVEYNMPSFILREFRVRHSD---SETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALE 6192
            +NL  NR KNR  N++ Y++ R+ LQ I    GSDYINA++IDGY+   AYIATQGPL+NT  DFWRM+W+  ++ +VM+++L E  R KC QYWP + + ++  G I V     + +  Y + +FI+      +S    S    R IRQ+QF  W + GVP +   L+ F+ ++        +  PI VHCSAGVGRTG F+ +   L+R+R E TVD+F  V ++R QR  MVQTEDQY F +   L+
Sbjct: 1510 SNLEINRAKNRYANVIAYDHSRILLQYINGVLGSDYINANYIDGYKRPNAYIATQGPLSNTFGDFWRMVWEQGTASIVMMTKLEERTRIKCDQYWPNKGTESYADGAITVTITDTKELAYYTIRTFIISANYSSNSSEFCSNKDKREIRQYQFTAWPDHGVPDNPMPLLMFLKRIRAGNPLSSR--PIIVHCSAGVGRTGAFIVIDTTLERIRHEMTVDIFGQVSIMRAQRNYMVQTEDQYVFVHEVVLD 1757          
The following BLAST results are available for this feature:
BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PTPRD3.143e-6565.90protein tyrosine phosphatase receptor type D [Sour... [more]
PTPRD2.812e-6565.90protein tyrosine phosphatase receptor type D [Sour... [more]
PTPRD2.812e-6565.90protein tyrosine phosphatase receptor type D [Sour... [more]
PTPRD3.143e-6565.90protein tyrosine phosphatase receptor type D [Sour... [more]
PTPRD2.366e-7166.39protein tyrosine phosphatase receptor type D [Sour... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ptp-31.952e-2752.24Tyrosine-protein phosphatase Lar-like [Source:Uni... [more]
ptp-37.883e-2352.24Tyrosine-protein phosphatase Lar-like [Source:Uni... [more]
ptp-33.598e-4652.24Tyrosine-protein phosphatase Lar-like [Source:Uni... [more]
ptp-37.993e-2352.24Tyrosine-protein phosphatase Lar-like [Source:Uni... [more]
ptp-34.435e-4652.24Tyrosine-protein phosphatase Lar-like [Source:Uni... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lar0.000e+035.54gene:FBgn0000464 transcript:FBtr0305950[more]
Lar0.000e+035.50gene:FBgn0000464 transcript:FBtr0331241[more]
Lar0.000e+035.50gene:FBgn0000464 transcript:FBtr0331242[more]
Lar0.000e+035.41gene:FBgn0000464 transcript:FBtr0331240[more]
Lar0.000e+034.61gene:FBgn0000464 transcript:FBtr0112800[more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ptprfb2.302e-7464.74protein tyrosine phosphatase receptor type Fb [Sou... [more]
ptprfb9.636e-7864.74protein tyrosine phosphatase receptor type Fb [Sou... [more]
ptprfb9.492e-7664.74protein tyrosine phosphatase receptor type Fb [Sou... [more]
ptprfb7.428e-7864.74protein tyrosine phosphatase receptor type Fb [Sou... [more]
ptprfb5.509e-9564.74protein tyrosine phosphatase receptor type Fb [Sou... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sema6d1.540e-7666.89semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070][more]
sema6d9.546e-7766.89semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070][more]
sema6d6.349e-7866.34semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070][more]
sema6d1.386e-7866.34semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070][more]
sema6d2.409e-7666.34semaphorin 6D [Source:Xenbase;Acc:XB-GENE-967070][more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ptprd8.335e-7166.39protein tyrosine phosphatase, receptor type, D [So... [more]
Ptprd5.678e-6866.39protein tyrosine phosphatase, receptor type, D [So... [more]
Ptprd8.327e-4666.39protein tyrosine phosphatase, receptor type, D [So... [more]
Ptprd2.933e-6266.39protein tyrosine phosphatase, receptor type, D [So... [more]
Ptprd6.087e-6266.39protein tyrosine phosphatase, receptor type, D [So... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P16621|LAR_DROME0.000e+034.61Tyrosine-protein phosphatase Lar OS=Drosophila mel... [more]
sp|Q64487|PTPRD_MOUSE3.972e-6766.39Receptor-type tyrosine-protein phosphatase delta O... [more]
sp|P23468|PTPRD_HUMAN1.136e-7066.39Receptor-type tyrosine-protein phosphatase delta O... [more]
sp|A7MBJ4|PTPRF_BOVIN4.512e-6965.07Receptor-type tyrosine-protein phosphatase F OS=Bo... [more]
sp|A4IFW2|PTPRF_DANRE5.607e-7764.74Receptor-type tyrosine-protein phosphatase F OS=Da... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3HSZ80.000e+037.51receptor-type tyrosine-protein phosphatase delta i... [more]
A0A1S3HQ626.812e-2036.78receptor-type tyrosine-protein phosphatase F isofo... [more]
A0A2T7NQE61.872e-7935.40Uncharacterized protein OS=Pomacea canaliculata OX... [more]
A0A1S3HRJ82.281e-6038.82tyrosine-protein phosphatase Lar isoform X2 OS=Lin... [more]
A0A1S3HQ572.284e-6038.82tyrosine-protein phosphatase Lar isoform X1 OS=Lin... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PTPRD3.476e-7167.05protein tyrosine phosphatase receptor type D [Sour... [more]
PTPRD2.619e-7267.05protein tyrosine phosphatase receptor type D [Sour... [more]
PTPRD3.968e-6467.05protein tyrosine phosphatase receptor type D [Sour... [more]
PTPRD1.972e-7266.67protein tyrosine phosphatase receptor type D [Sour... [more]
ptprfb4.076e-4265.23protein tyrosine phosphatase receptor type Fb [Sou... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ptpra1.413e-17146.23protein tyrosine phosphatase receptor type A [Sour... [more]
ptprsa3.553e-15254.81protein tyrosine phosphatase receptor type Sa [Sou... [more]
ca16b8.738e-12138.37carbonic anhydrase XVI b [Source:ZFIN;Acc:ZDB-GENE... [more]
ptprk3.371e-12039.73protein tyrosine phosphatase receptor type K [Sour... [more]
ENSPMAT00000002738.14.273e-11638.18pep scaffold:Pmarinus_7.0:GL477626:22501:55781:-1 ... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
PTP14.666e-3334.49Phosphotyrosine-specific protein phosphatase; deph... [more]
PTP24.112e-2127.13Nuclear phosphotyrosine-specific phosphatase invol... [more]
PTP34.098e-833.33Phosphotyrosine-specific protein phosphatase; invo... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO469618.968e-5557.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO438540.000e+050.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO453820.000e+047.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO481871.564e-17046.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO450814.602e-16642.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PTPRD1.859e-7265.33receptor-type tyrosine-protein phosphatase delta [... [more]
PTPRD3.905e-9065.33receptor-type tyrosine-protein phosphatase delta [... [more]
PTPRD2.452e-7266.17receptor-type tyrosine-protein phosphatase delta [... [more]
PTPRD3.648e-6565.40receptor-type tyrosine-protein phosphatase delta [... [more]
PTPRD2.595e-6265.23receptor-type tyrosine-protein phosphatase delta [... [more]
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BLAST of Receptor type tyrosine protein phosphatase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000041927.10.000e+099.61SMESG000041927.1[more]
SMESG000041927.10.000e+099.60SMESG000041927.1[more]
SMESG000041927.10.000e+099.60SMESG000041927.1[more]
SMESG000041927.10.000e+099.60SMESG000041927.1[more]
SMESG000068618.14.615e-5436.75SMESG000068618.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005517 ID=SMED30005517|Name=Receptor type tyrosine protein phosphatase|organism=Schmidtea mediterranea sexual|type=transcript|length=6411bp
ATGCTCCTGAATTTTTTATGGGTTTCGAAAATTTTGGAAATTATTTTTTA
TGTAAAAATTCACGTTTATGTTTTGTACAAGATTAGTTATTTTAATATTT
GCAAATGTCTCGTTTGGAATTACCCGTTAGTTGGATATAAATGGAAGACT
TTCTTGATTATCCAAATTATTCTTTCAAATCAAATCGTTTTTGCTCAATG
GTTTCGTTTACAGGTGATGAAGGAGCATTTGAATCCGAGAAAAGGAGCGG
CCAAAATTATAGTGGCACCTCAGTCCCAAACTGTTCTTCTGGGAGAAACT
GCAATTTTCTTCTGTCAAATAGATGGCAATCCATCATTTCATCTGAGCTT
ACTTTACAATGGAATGAAGAAATATGTGATTCCTATACCAAGTGGTTTGA
TGTTGAGAATACCAGATGTAAAGTTAACGGATGGTAAGCCAGTCAGAATA
GATTGCATAGTCAGAAATCCCTCTGCCGAAGAAAAGAAAACAGCATATTT
GAATGTTACCGATCCAAGTAAAGATTTACCAAATGGTTTTCCAAGATTCA
AATTAATCAAAGACTTTTATGTGGGAGACGTTGGTCAAAATATGAAAATG
AATTGTGATGTTGAAGGAGGACTTCCAATAAAATTCAATTGGTTCAAAGA
CAATGCTCCATTAGATTTATCCGAACCTAGAAGAACAATGTTAAGATCTG
GATCCATATTTTTCGACAGGTTATTGAAAGAAGACAGCGGAATTTATGAA
TGTCGCGCAATTAATCCAGTAGGCTCAATTCTATCAATTAAAATGAAATT
AGAAATAAGAAATACACCAATTACTCCGCAGTGGATTCATAGACCACAGG
ATGTGGAAGTCCGACCAGGACATGGGGTAAATCTTACGTGTACAGCAAAA
GGCAATCCACCTCCCCAGCTGAGGTGGTTAACCCAATATCATAGGCCAAT
AAATGATTTGACAGATAAAGAGTCAATATTATTGTTGACTGATATTACGG
AACCTGCGTCGTATATTTGTCGGGCAAATAATAGCATGGGCGTAATACAA
CATGCGGTTCAAGTCAGAGTAAAAAAAATACCCAAGATACCAGTAAACAT
AACATGTTTAAATATTGGACCAACAGATGCTCAAATTTCATGGGAGCAAA
ATCCTGAATCAGATTTACCGGCGGAATCGTTTACTCTCATGATTGCGGAT
TTATCCATTGACAATACAGTTCTCGGATTAAAACAAATCCCAAATATTCA
TCCATGGCCGCCTGATAATAAAAATATAACTTACAATGTCACCGATCTAC
GACCATATACAAGATATTCTGTAAAAGTCATCGCTTTCAGTAAAACATTA
GGGGACTCAGATCCAAGCAAAACTATCGTAATAGAAACAAAAGAATTGCC
GCCAAGTTCTCCACCACAATCAGTTTATGCAACTGCTGATACATTTACTT
CAATAACAGTAAAATGGGCTCCACCAATAGAGGCAAATGGGAAGATTACG
GATTATAATGTATATTACAGCAGAAACTTACAGCATCCAATTAATCAGTG
GCAAAAATCCGAAACTACCAGACAACATGTCCGTATAACAGACCTCTTTA
CTAATAATACATATCATATAAAAGTCAATGCAGTTAACAGTGCTGGTCCC
GGACCAGTAAGTGAGCCTTTTCCCATTATAGTGAGGCCTGGAGTTCCTCC
ACAGCCTCACAATTTTAGGGGTGCCGGTATCACATCGACATCAATCAACT
TGATTTGGTCTCCTCCACAATTGCCATCGAAACTAGTGTTATTGGATTAT
GTGTTAAAATACAAAGTCATAAGCGGCAAGCATATTCCGACCCTTACTAA
TAAAGAAGAAGAAATTAAAATTTTACCCGATCGTACAGACTATCGAATGA
CAGAATTATGGCCGAACACGTTGTATCATATCAGTCTGGCCGCTAGAACT
GAGCACGGAGTTGGAGTATCGAATACAATGAATGTTCGCACGGAAAATCG
AGTTCCAAACTCTCCAATCGGAATAGATGTTCGAACTCTCAGTCCGACAT
CAATAGCCATTAGGTGGAGAAAAGGAATGGATAATGAAGAGTCAATTAGT
AGTTTTAAAATTAAAGTGATCAAATTGAAAAGCATCGAAACTGTGGATAA
TAGCAATGAAATGCATGTTCAAATCCAAAGCGTTCCTGCAAAAACGAAAA
ATCAGAGTGATATATACGAGTATATCATAAACGATTTGGAGACAGGTCAA
AACTACAAAATTGTGTTGTGGTCTGTTGGAAGCAGCGGCTTAAGTGCTCC
TTTTATTTTCGACATAGTTAAAACAAGACCGGGCAATATAGTTCCATCTC
CTCCGCTAAATATACGACTTAATCAGTTGAGACAGAAAACGGAAAGTGGA
CTAACACTTCTGTTAGCAGACATTGCTTGGGACCCCCCAATCAATAGTCA
CGGAACAATTAGGGCTTATCGGATTAGACATAACTTAGTCGGACCTCAAA
ATCTCATTGAAAGTTTAAAAAGAAGAAGTCTCTCTGTAAAAGTTTATGAA
AAAAATGTCACTGGAACTAATTATTGTACGGAATTTGGTGAATTGGGTTA
CGGAAAAGTCTACGAATTCTCAGTTGCTGCCATGAATACCGCAGACATTG
GATTAGAAGTCAAATTGAATGTATCAACTAGAGAAAGTGCTCCAGATAGC
TATCCGGTTTCGATAGACATAACAGGAATAACAAGTCACTCTGTGAATAT
ATCTTGGCAGCCTCCCTTAGTTGAAAATCACAATGGAATATTAGTGAATT
ATCAAGTTGCATATTTCACTTATGGATTGAAGAATACGACAATTCGCACA
ACTAGTACACCAAATTTGTACGCTCTCATCGAAGGATTACAAGAGAATAT
GCTATATACTTTTCAAGTCAGAGCTTTTACCAAAGTTGGTCAAGGTCCAT
GGAGTTCTGATGTCAATTTTCGAACTGTTGTTTTATTGCCTGACCCTCCA
ATAAATATTGAGGCTAGCCGAATTAATGAAAACCAAATAAAAGTAACTTG
GGAGTTATCACATACAAACAATATAAAAGTTGTTGGATTTAAAATATATT
ATTGCTTACAAACCATTCCAAAAGACATCGAAAGTTGCAATACCCTTGAC
GTTGGACCTGTAACTATGGTTACATTAGGAAATGTCCAATACAATTCAGA
TTATCAAGTTGGAATAAAGTCCAAGGGAATTGACAATCGCTATGGACTAA
TCAGCAACATAGCGACGGCTAAAATATCGGAACTTCCAGTTATTCGAGAT
TTGTCGGTTAGTAGTTTAAAATGTGAAGGAAAAGTGCGATCTATGGAAAT
TCAATGGCAAAAACCTAAGACTCATGACAATTTGAGTAAATTTCGGGTAA
CAATTAATGGATATGCGTCGTACACTAAAGAAACGGGAGAGGTGGAGAAA
TTTAAGAGTTCCTTTAAGCCCCGAGAAGTTGATTTTGTGGATAAATATAT
AAAATTTGTTCTTGGATTGAAAGATATGTCACCAAATATGGTGTATGATA
TCTCAGTTCAAACGGTATATAAAAGAGATGGTGAATCCTCGTTTTATGGA
GCTATTCAAAATACTAGTTGCCGAACGCTAATGGCTCGACCGAAATTTGT
TTCTACTCCAGAAATTATTCTAGTTAATAGAACATCCCTATCAATTTATC
TACGAATACTACGAGTTACAGAACATTTGGGAATTATACGTACATATTAC
CTTATTATAGAAGAATCAATTCACACTCAAAAGACGAATTTTTCCAAGTA
TTCGTTTGAATCGCTTCAATCTGCATCTAAACCAATATCCTACAGTCCAA
TATTAGTAGCAGAATTTTCAAATGATATTTTTAAGAAAGGATCAAACATA
AGCTTTTGGGTAGGACAAGATATATGGAGATCACAATATCCTAAACCTAT
TTACAATACGGATTCCTTACTAATGAGACCAATCATGTTTGACATGAAAA
AAAGTTATAAAATGTTTCTCAGAGCTTGTATATTCACTGAAATCACAAGT
TTTGCAAATGATGACTTTTATCCTTGTACAGATAGTTCATGGAGTCGATT
GTTCAACTTCGAGGAGTCTCCTGCCATAAATAAACTTCTTCCAAAAAAAC
AAACAGATGTATTTACAGTTTCTATTATTGCTATTATAATCGGATTGGGA
GTTATTGCTTTGATCAGTATTGCCGTTGGTTGTTTTATGAAACGCCGGAG
ACCAAAAAGATATTACAACAGTCCTCAGGAACTCATAATGAACGGTGATC
CAAGTTTAAAACAAGCTCTGATTTCTCAAGCTGTTTCCGGGCCCCCATCA
TATGTTCCATTATCTCACTCAAACGGTATCGTCACTGACATGGATTCATC
AATTAAATCCAACTTCAAAAATACAATTGTGAATAAACATCCTCCGATTC
CATCTGGTCATCTTGCTGATTACATTGCGGCTCTTAAAACTAATGACAAT
GCCAAATTCACAGAAGAATATGAGTCTATAGATCCTGGGCATCATTTTAC
TTGGATTCAATCAAATCTAGAGATTAATAAACCAAAAAACAGATATGCCA
ATGTAATAGCATATGATCACAGTCGAGTTGTCTTATCAACTTTGAATGAT
ATCCCCGGTTCTGATTACATAAATGCAAATTATTGTGATGGATATAGAAA
ACAAAATGCCTATATTGCAACTCAGGGACCGTTGCCTGAAACTTTTGAAG
CCTTTTGGCGTATGGTATGGGAAAGTCGTTGTGCTTTGATTGTCATGATG
ACCAAATTGGAAGAAAGATTAAGGGTCAAGTGTGATCAGTATTGGCCAAC
AAGAGGAAGTGAAGCCTATGCAGAGAGTGGGTTATCTATCAATCACTTAG
AGACTGTAGAACTAGCATATTATACTATGAGAAAATTTAGTCTTACTAAA
AAGTTATCTTCTGACCCCAATGGGAGTAAAGAAACTAGAGATGTTTTTCA
TTTCCAATTTACTGGATGGCCAGATCATGGTGTCCCTGATACTGCGCTTC
CTTTGTTAATGTTTATAAAACGTGTGAGGTCTTGCTGTCCTTCAGACTCC
GGTCCAATAGTCGTTCATTGTTCAGCGGGAGTTGGAAGAACTGGTGCATA
CATTGTACTAGATAGTCAATTATCTCAAATACAGCATGAAAAGGTTGTTG
ATGTATATGGAATCGTAAGTAGATTAAGAGCTCAAAGAAATTATATGGTG
CAGACTGAAGAGCAATATGTATTTATTTATGATGCATTATTAGAGGCATC
ATTATGCGGCAATACTGAAGTTTCAATTAGACATTTGCATGCTCATGTTA
CAAAATTAAAACAACCTTTACCAGTGTTAGGAGTCACTCCTTCAAATCAG
TATTCAACTGGAATGGAATTAGAGTTCAAACATTTGTCAGAACTAAGCAC
AAGACCAAGACAATTCAACACCGCAAACCTTCCAGAAAACCGTTTAAAAA
ACCGTTTGATAAATATTTTACCCTATGAAAATCGAAGAGTTTGTTTGCAG
CCTATTCGCAATCAAGACGGTTCGGATTATATAAATGCTAGCTTCATAGA
TGGATATAGATCACAGAAAGCTTATATAGCTACTCAAGGCCCGTTAGCCA
ATACGATTGTTGACTTTTGGCGGATGTTGTGGCAACATAATTCCAGTATT
GTCGTTATGCTCAGTCAGCTTCGGGAAATGGGACGGGAAAAGTGTTCCCA
GTATTGGCCTACAGAGAGGTCAGCAACGTTTGGCCAAATTATTGTTGAAC
CAATGGTTGAGTATAATATGCCTAGTTTCATTTTGAGAGAATTTAGAGTA
CGTCATTCTGACTCTGAAACCCATAATCGTACAATAAGACAATTTCAATT
TCTTGATTGGGCAGAACAAGGAGTTCCGCGATCTGGCGAAAGTCTAATAG
ATTTCATTGGTCAAGTTCATAAAACAAAAGAACAGTTTGGTCAAGAGGGT
CCAATTACAGTTCATTGCAGCGCTGGTGTTGGCAGAACTGGAGTTTTTCT
AGCACTCTCGATCGTTTTAGATAGAATGCGATCAGAAGGCACAGTTGACT
TATTTCAGACAGTGAGACTTCTGCGGATGCAAAGGCCTTGTATGGTACAA
ACCGAAGATCAGTATCAATTTTGTTATTTAACTGCTTTGGAATATTTGAG
TTCATTCGATCAGTTTCTATCTTAATACTTTTTTCGTTTTTAATGGAATT
TTTAATTTGAAATTATTCGTTATTAGTTGATAATTTTAGAAACACTGTAG
AGTAAAACAATTAGAATTTCGTTATTTGGAATCCACATATTGCCAAGTAA
ATAATGTTATTAAATATTTACAATGAACTAGACAAACTATTTAATTGCAT
TTAATGATTTG
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protein sequence of SMED30005517-orf-1

>SMED30005517-orf-1 ID=SMED30005517-orf-1|Name=SMED30005517-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2075bp
MLLNFLWVSKILEIIFYVKIHVYVLYKISYFNICKCLVWNYPLVGYKWKT
FLIIQIILSNQIVFAQWFRLQVMKEHLNPRKGAAKIIVAPQSQTVLLGET
AIFFCQIDGNPSFHLSLLYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRI
DCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKLIKDFYVGDVGQNMKM
NCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYE
CRAINPVGSILSIKMKLEIRNTPITPQWIHRPQDVEVRPGHGVNLTCTAK
GNPPPQLRWLTQYHRPINDLTDKESILLLTDITEPASYICRANNSMGVIQ
HAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIAD
LSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTRYSVKVIAFSKTL
GDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKIT
DYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGP
GPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDY
VLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAART
EHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESIS
SFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQ
NYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESG
LTLLLADIAWDPPINSHGTIRAYRIRHNLVGPQNLIESLKRRSLSVKVYE
KNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDS
YPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRT
TSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDPP
INIEASRINENQIKVTWELSHTNNIKVVGFKIYYCLQTIPKDIESCNTLD
VGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRD
LSVSSLKCEGKVRSMEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEK
FKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYG
AIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYY
LIIEESIHTQKTNFSKYSFESLQSASKPISYSPILVAEFSNDIFKKGSNI
SFWVGQDIWRSQYPKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITS
FANDDFYPCTDSSWSRLFNFEESPAINKLLPKKQTDVFTVSIIAIIIGLG
VIALISIAVGCFMKRRRPKRYYNSPQELIMNGDPSLKQALISQAVSGPPS
YVPLSHSNGIVTDMDSSIKSNFKNTIVNKHPPIPSGHLADYIAALKTNDN
AKFTEEYESIDPGHHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLND
IPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMM
TKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTK
KLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDS
GPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMV
QTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQ
YSTGMELEFKHLSELSTRPRQFNTANLPENRLKNRLINILPYENRRVCLQ
PIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSI
VVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRV
RHSDSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEG
PITVHCSAGVGRTGVFLALSIVLDRMRSEGTVDLFQTVRLLRMQRPCMVQ
TEDQYQFCYLTALEYLSSFDQFLS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036179Ig-like_dom_sf
IPR036116FN3_sf
IPR000242PTPase_domain
IPR003598Ig_sub2
IPR003595Tyr_Pase_cat
IPR003599Ig_sub
IPR003961FN3_dom
IPR013783Ig-like_fold
IPR029021Prot-tyrosine_phosphatase-like
IPR013098Ig_I-set
IPR016130Tyr_Pase_AS
IPR007110Ig-like_dom
IPR000387TYR_PHOSPHATASE_dom
Vocabulary: molecular function
TermDefinition
GO:0004725protein tyrosine phosphatase activity
GO:0005515protein binding
GO:0016791phosphatase activity
GO:0004721phosphoprotein phosphatase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0006470protein dephosphorylation
GO:0016311dephosphorylation
GO:0035335peptidyl-tyrosine dephosphorylation
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000242PTP type protein phosphatasePRINTSPR00700PRTYPHPHTASEcoord: 1555..1562
score: 71.4
coord: 1663..1680
score: 54.51
coord: 1749..1759
score: 67.54
coord: 1571..1591
score: 67.14
coord: 1702..1720
score: 71.15
coord: 1733..1748
score: 41.14
IPR000242PTP type protein phosphataseSMARTSM00194PTPc_3coord: 1804..2067
e-value: 5.5E-122
score: 421.2
coord: 1502..1768
e-value: 3.8E-119
score: 411.8
IPR000242PTP type protein phosphatasePFAMPF00102Y_phosphatasecoord: 1526..1765
e-value: 3.0E-80
score: 269.2
coord: 1830..2063
e-value: 1.5E-78
score: 263.6
IPR000242PTP type protein phosphatasePROSITEPS50055TYR_PHOSPHATASE_PTPcoord: 1805..2065
score: 58.687
IPR000242PTP type protein phosphatasePROSITEPS50055TYR_PHOSPHATASE_PTPcoord: 1503..1766
score: 56.574
IPR003598Immunoglobulin subtype 2SMARTSM00408igc2_5coord: 288..347
e-value: 0.0015
score: 27.8
coord: 193..258
e-value: 2.9E-5
score: 33.5
IPR003595Protein-tyrosine phosphatase, catalyticSMARTSM00404ptp_7coord: 1961..2064
e-value: 1.6E-39
score: 147.3
coord: 1664..1765
e-value: 7.9E-40
score: 148.3
IPR003961Fibronectin type IIISMARTSM00060FN3_2coord: 669..765
e-value: 0.0012
score: 28.1
coord: 1100..1196
e-value: 3.9
score: 15.0
coord: 997..1082
e-value: 0.0039
score: 26.4
coord: 469..551
e-value: 5.5E-10
score: 49.2
coord: 361..453
e-value: 4.3E-7
score: 39.6
coord: 782..884
e-value: 4.0
score: 14.9
coord: 566..655
e-value: 2.8E-9
score: 46.8
coord: 899..982
e-value: 1.0E-11
score: 55.0
IPR003961Fibronectin type IIIPFAMPF00041fn3coord: 364..449
e-value: 3.7E-6
score: 27.2
coord: 470..553
e-value: 2.8E-11
score: 43.6
coord: 902..985
e-value: 1.8E-12
score: 47.4
coord: 567..655
e-value: 9.6E-9
score: 35.5
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 999..1095
score: 14.691
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 671..778
score: 10.714
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 901..995
score: 20.56
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 363..466
score: 14.73
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 784..899
score: 6.872
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 568..667
score: 13.491
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 471..564
score: 22.233
IPR003961Fibronectin type IIICDDcd00063FN3coord: 997..1070
e-value: 1.24525E-7
score: 49.4171
IPR003961Fibronectin type IIICDDcd00063FN3coord: 361..463
e-value: 1.50003E-9
score: 54.8099
IPR003961Fibronectin type IIICDDcd00063FN3coord: 902..992
e-value: 4.76235E-17
score: 75.9959
IPR003961Fibronectin type IIICDDcd00063FN3coord: 566..664
e-value: 2.44556E-10
score: 57.1211
IPR003961Fibronectin type IIICDDcd00063FN3coord: 470..561
e-value: 1.66429E-17
score: 77.5367
IPR003961Fibronectin type IIICDDcd00063FN3coord: 782..884
e-value: 3.34694E-4
score: 39.4019
IPR003961Fibronectin type IIICDDcd00063FN3coord: 669..775
e-value: 2.3064E-5
score: 42.8687
IPR003599Immunoglobulin subtypeSMARTSM00409IG_3ccoord: 90..170
e-value: 2.6
score: 16.6
coord: 282..358
e-value: 8.9E-7
score: 38.5
coord: 187..270
e-value: 2.4E-5
score: 33.7
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 273..362
e-value: 1.8E-14
score: 55.7
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 997..1096
e-value: 5.0E-10
score: 41.5
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 177..272
e-value: 3.8E-15
score: 57.8
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 888..995
e-value: 9.7E-24
score: 85.6
coord: 776..887
e-value: 1.1E-7
score: 33.6
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 662..775
e-value: 1.4E-7
score: 33.6
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 470..557
e-value: 2.5E-21
score: 78.0
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 363..469
e-value: 1.5E-11
score: 46.4
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 80..176
e-value: 1.6E-6
score: 30.1
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 558..661
e-value: 6.3E-14
score: 54.1
IPR029021Protein-tyrosine phosphatase-likeGENE3DG3DSA:3.90.190.10coord: 1772..2073
e-value: 2.6E-111
score: 373.7
IPR029021Protein-tyrosine phosphatase-likeGENE3DG3DSA:3.90.190.10coord: 1473..1771
e-value: 5.7E-113
score: 379.1
IPR029021Protein-tyrosine phosphatase-likeSUPERFAMILYSSF52799(Phosphotyrosine protein) phosphatases IIcoord: 1480..1766
IPR029021Protein-tyrosine phosphatase-likeSUPERFAMILYSSF52799(Phosphotyrosine protein) phosphatases IIcoord: 1800..2070
IPR013098Immunoglobulin I-setPFAMPF07679I-setcoord: 279..357
e-value: 3.2E-7
score: 30.3
IPR007110Immunoglobulin-like domainPFAMPF13895Ig_2coord: 194..268
e-value: 1.3E-8
score: 35.0
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 181..268
score: 10.68
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 276..356
score: 11.225
NoneNo IPR availablePANTHERPTHR19134:SF203RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE Fcoord: 237..825
NoneNo IPR availablePANTHERPTHR19134PROTEIN-TYROSINE PHOSPHATASEcoord: 1417..2065
coord: 237..825
NoneNo IPR availablePANTHERPTHR19134:SF203RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE Fcoord: 1417..2065
coord: 864..938
NoneNo IPR availablePANTHERPTHR19134PROTEIN-TYROSINE PHOSPHATASEcoord: 864..938
NoneNo IPR availableCDDcd14554R-PTP-LAR-2coord: 1825..2063
e-value: 7.59469E-147
score: 452.364
NoneNo IPR availableCDDcd00096Igcoord: 199..263
e-value: 6.9852E-10
score: 54.9408
NoneNo IPR availableCDDcd14553R-PTPc-LAR-1coord: 1524..1769
e-value: 7.54017E-153
score: 468.8
NoneNo IPR availableTMHMMTMhelixcoord: 1390..1412
IPR016130Protein-tyrosine phosphatase, active sitePROSITEPS00383TYR_PHOSPHATASE_1coord: 2004..2014
IPR016130Protein-tyrosine phosphatase, active sitePROSITEPS00383TYR_PHOSPHATASE_1coord: 1705..1715
IPR000387Tyrosine specific protein phosphatases domainPROSITEPS50056TYR_PHOSPHATASE_2coord: 1983..2056
score: 22.205
IPR000387Tyrosine specific protein phosphatases domainPROSITEPS50056TYR_PHOSPHATASE_2coord: 1686..1757
score: 20.366
IPR036179Immunoglobulin-like domain superfamilySUPERFAMILYSSF48726Immunoglobulincoord: 182..276
IPR036179Immunoglobulin-like domain superfamilySUPERFAMILYSSF48726Immunoglobulincoord: 276..366
IPR036179Immunoglobulin-like domain superfamilySUPERFAMILYSSF48726Immunoglobulincoord: 85..180
IPR036116Fibronectin type III superfamilySUPERFAMILYSSF49265Fibronectin type IIIcoord: 782..992
IPR036116Fibronectin type III superfamilySUPERFAMILYSSF49265Fibronectin type IIIcoord: 564..727
IPR036116Fibronectin type III superfamilySUPERFAMILYSSF49265Fibronectin type IIIcoord: 985..1086
IPR036116Fibronectin type III superfamilySUPERFAMILYSSF49265Fibronectin type IIIcoord: 360..566