Phosphatidylinositol 4-kinase type 2-beta

Overview
NamePhosphatidylinositol 4-kinase type 2-beta
Smed IDSMED30005458
Length (bp)1083
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Phosphatidylinositol 4-kinase type 2-beta (SMED30005458) t-SNE clustered cells

Violin plots show distribution of expression levels for Phosphatidylinositol 4-kinase type 2-beta (SMED30005458) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Phosphatidylinositol 4-kinase type 2-beta (SMED30005458) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Phosphatidylinositol 4-kinase type 2-beta (SMED30005458) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005458

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30005458h1SMcG0000961 tr5_11049mu_Smed_v1PMID:25558068
Reuter et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
cephalic gangliaSMED30005458h1SMcG0000961 tr5_11049mu_Smed_v1PMID:25558068
Reuter et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
esophagusSMED30005458h1SMcG0000961 tr5_11049mu_Smed_v1PMID:25558068
Reuter et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
pharynx pouchSMED30005458h1SMcG0000961 tr5_11049mu_Smed_v1PMID:25558068
Reuter et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
ventral nerve cordSMED30005458h1SMcG0000961 tr5_11049mu_Smed_v1PMID:25558068
Reuter et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
posterior region of the whole animalSMED30005458h1SMcG0000961 tr5_11049mu_Smed_v1PMID:25558068
Reuter et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
X1 cellSMED30005458h1SMcG0000961 SmedASXL_008923SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30005458h1SMcG0000961 SmedASXL_008923SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Human
Match: NOC4L (nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461])

HSP 1 Score: 90.8929 bits (224), Expect = 2.161e-19
Identity = 58/210 (27.62%), Postives = 99/210 (47.14%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNEMENQD--------------EEMLLDIKSLQNHFDIEVRNLANEINSKLN 897
            + MWL FLK  +P  L   V++ + D +L  +  P +  D + ++ +      +++L  LF L+  + + Y   Y  LY LL   +F   + +RFF      LSS  +P  +   FAKRL++L  +A     L M++  + NL++ H     L+HR    E++                 E  L ++++LQ H+  EV   A+ IN  L+
Sbjct:  253 QAMWLSFLKHKLPLSLYKKVLLIVHDAILPQLAQPTLMIDFLTRACDLGGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALL-MVLPFICNLLRRHPACRVLVHRPHGPELDADPYDPGEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALS 461
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Human
Match: NOC4L (nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461])

HSP 1 Score: 90.8929 bits (224), Expect = 2.161e-19
Identity = 58/210 (27.62%), Postives = 99/210 (47.14%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNEMENQD--------------EEMLLDIKSLQNHFDIEVRNLANEINSKLN 897
            + MWL FLK  +P  L   V++ + D +L  +  P +  D + ++ +      +++L  LF L+  + + Y   Y  LY LL   +F   + +RFF      LSS  +P  +   FAKRL++L  +A     L M++  + NL++ H     L+HR    E++                 E  L ++++LQ H+  EV   A+ IN  L+
Sbjct:  253 QAMWLSFLKHKLPLSLYKKVLLIVHDAILPQLAQPTLMIDFLTRACDLGGALSLLALNGLFILIHKHNLEYPDFYRKLYGLLDPSVFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALL-MVLPFICNLLRRHPACRVLVHRPHGPELDADPYDPGEEDPAQSRALESSLWELQALQRHYHPEVSKAASVINQALS 461
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Celegans
Match: T20B12.3 (pep chromosome:WBcel235:III:7382115:7383906:1 gene:WBGene00020601.1 transcript:T20B12.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T20B12.3)

HSP 1 Score: 67.3958 bits (163), Expect = 4.753e-12
Identity = 52/211 (24.64%), Postives = 91/211 (43.13%), Query Frame = 1 
Query:  307 HEQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNEMENQD--------------EEMLLDIKSLQNHFDIEVRNLANEINSKLN 897
            ++ +W+  +   + + L L +I  +   V+  +  P   AD   K F+K+   GI+SL A+F+L+  +   Y   YD +Y L    +            + S LSS  +P  I   F KRLS+    A      P++  L+ NL+  H   + L+HR     + +                E  L ++K LQ H++  VR  A+ ++  + 
Sbjct:  194 YDNVWMAVMNGKISDKLTLKLIPYITQNVISKLKAPFKSADFFFKMFDKTDYHGILSLGAIFRLISEHNFEYPKFYDKVYSLTNPSLLYMSQKESILTLLDSFLSSTHLPTYITASFLKRLSRCLLLAPIDAQEPIL-GLIRNLVIRHPNCSELVHREVPQTLYDDPFDNDETDLHKTRALESSLWEMKLLQCHWNQSVRKRAHFVDKSIQ 403
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Fly
Match: CG2875 (gene:FBgn0029672 transcript:FBtr0070586)

HSP 1 Score: 77.0258 bits (188), Expect = 3.407e-15
Identity = 56/197 (28.43%), Postives = 94/197 (47.72%), Query Frame = 1 
Query:  349 EPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEK-SRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSS----NEMENQDE----------EMLLDIKSLQNHFDIEVRNLANEINSKL 894
            E L   +++ L + V+++++DP    D ++ S  +      +++L+ +F L+    I Y  VY+ LY++    +F + + +R F      L+S  +P N+   F KRL++L    S T    +M+R V NL+  H G   LI  + +    ++  NQ E            L +I  LQ H   EV N A  INS L
Sbjct:  247 EKLHRQILVVLLERVINHLNDPIQLTDFLMDSLHQFDGPIALLALQGIFTLMQKQNITYPDVYEKLYNMFYPRMFHNKYKARLFYLADIFLTSTHLPENLVAAFVKRLARLALQ-SPTEDAVIMIRFVCNLLLRHTGLQKLIRASHAVDEVSDPYNQTETDPVKSEAINSSLWEITLLQKHVVPEVANAARFINSSL 442
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Fly
Match: CG2875 (gene:FBgn0029672 transcript:FBtr0333793)

HSP 1 Score: 77.0258 bits (188), Expect = 3.526e-15
Identity = 56/197 (28.43%), Postives = 94/197 (47.72%), Query Frame = 1 
Query:  349 EPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEK-SRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSS----NEMENQDE----------EMLLDIKSLQNHFDIEVRNLANEINSKL 894
            E L   +++ L + V+++++DP    D ++ S  +      +++L+ +F L+    I Y  VY+ LY++    +F + + +R F      L+S  +P N+   F KRL++L    S T    +M+R V NL+  H G   LI  + +    ++  NQ E            L +I  LQ H   EV N A  INS L
Sbjct:  246 EKLHRQILVVLLERVINHLNDPIQLTDFLMDSLHQFDGPIALLALQGIFTLMQKQNITYPDVYEKLYNMFYPRMFHNKYKARLFYLADIFLTSTHLPENLVAAFVKRLARLALQ-SPTEDAVIMIRFVCNLLLRHTGLQKLIRASHAVDEVSDPYNQTETDPVKSEAINSSLWEITLLQKHVVPEVANAARFINSSL 441
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Fly
Match: CG2875 (gene:FBgn0029672 transcript:FBtr0070587)

HSP 1 Score: 77.0258 bits (188), Expect = 3.526e-15
Identity = 56/197 (28.43%), Postives = 94/197 (47.72%), Query Frame = 1 
Query:  349 EPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEK-SRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSS----NEMENQDE----------EMLLDIKSLQNHFDIEVRNLANEINSKL 894
            E L   +++ L + V+++++DP    D ++ S  +      +++L+ +F L+    I Y  VY+ LY++    +F + + +R F      L+S  +P N+   F KRL++L    S T    +M+R V NL+  H G   LI  + +    ++  NQ E            L +I  LQ H   EV N A  INS L
Sbjct:  246 EKLHRQILVVLLERVINHLNDPIQLTDFLMDSLHQFDGPIALLALQGIFTLMQKQNITYPDVYEKLYNMFYPRMFHNKYKARLFYLADIFLTSTHLPENLVAAFVKRLARLALQ-SPTEDAVIMIRFVCNLLLRHTGLQKLIRASHAVDEVSDPYNQTETDPVKSEAINSSLWEITLLQKHVVPEVANAARFINSSL 441
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Zebrafish
Match: noc4l (nucleolar complex associated 4 homolog [Source:NCBI gene;Acc:554096])

HSP 1 Score: 106.301 bits (264), Expect = 7.582e-25
Identity = 65/217 (29.95%), Postives = 114/217 (52.53%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE--------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNL 915
            EQMWL FLK  +P  +   +++ L + +L  + DP +  D +  +++      +++L  LF L+  + ++Y   Y  LY+LL   IF   + +RFF   +  LSS  +P  +   F KRL++L+ +A  T  L +++  + NL++ H     LIHR S+ +        ME +D       E  L +IK+LQNH+  +V   A  IN  L+++ +++
Sbjct:  262 EQMWLLFLKYKLPGSMYKKILVILHESILPQMSDPKLMMDFLSAAYDIGGAISLLALNGLFVLIHEHNLDYPDFYKKLYNLLDPSIFHVKYRARFFHLANIFLSSTHLPVYLVAAFVKRLARLSLTAPPTALL-ILLPFICNLIRRHPSCRVLIHRPSAADEPCDDPYVMEEEDPAQCHALESSLWEIKTLQNHYHPDVSKAATMINEPLSAQEEDI 477
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Xenopus
Match: noc4l (nucleolar complex associated 4 homolog [Source:NCBI gene;Acc:493276])

HSP 1 Score: 97.4413 bits (241), Expect = 1.122e-21
Identity = 61/212 (28.77%), Postives = 109/212 (51.42%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE-------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSR 903
            E++W+ FLK  +   L   V++ L + +L ++  P +  D +  +++      +++L  LF L+  + + Y   Y  LY LL+  IF   + +RFF   +  LSS  +P  +   FAKRL++LT +A     L M++  + NL++ H    +LIHR ++ +       ME QD       E  L +++ LQ H+  +V   AN I+  L+++
Sbjct:  264 ERVWMSFLKHQLSVSLYKKVLLILHESILPHMSKPTLMIDFLTAAYDVGGAISLLALNGLFILIHQHNLEYPDFYKKLYSLLEPSIFHVKYRARFFHLANLFLSSTHLPIYLVAAFAKRLARLTLTAPP-QVLLMIIPFICNLIRRHPACRALIHRPNTGDLATDPYIMEEQDPAKSQALESSLWELEVLQQHYHGDVVRAANVISRALSAQ 474
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Mouse
Match: Noc4l (NOC4 like [Source:MGI Symbol;Acc:MGI:2140843])

HSP 1 Score: 100.523 bits (249), Expect = 8.842e-23
Identity = 60/210 (28.57%), Postives = 102/210 (48.57%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNEMENQD--------------EEMLLDIKSLQNHFDIEVRNLANEINSKLN 897
            ++MWL FLK  +P  L   V++A+ D +L ++  P +  D +  + +      +++L  LF L+  + + Y   Y  LY LL   IF   + +RFF      LSS  +P  +   FAKRL++L  +A     L M++ L+ NL++ H     ++HR    E++                 E  L ++++LQ H+  EV   A+ IN  L+
Sbjct:  253 QEMWLGFLKHKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFLTSACDVGGAISLLALNGLFILIHKHNLEYPDFYQKLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALL-MVLPLICNLLRRHPACRVMVHRPQGPELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSKAASVINQVLS 461
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. UniProt/SwissProt
Match: sp|Q5I0I8|NOC4L_RAT (Nucleolar complex protein 4 homolog OS=Rattus norvegicus OX=10116 GN=Noc4l PE=2 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 3.610e-22
Identity = 60/210 (28.57%), Postives = 102/210 (48.57%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNEMENQD--------------EEMLLDIKSLQNHFDIEVRNLANEINSKLN 897
            ++MWL FLK  +P  L   V++A+ D +L ++  P +  D +  + +      +++L  LF L+  + + Y   Y  LY LL   IF   + +RFF      LSS  +P  +   FAKRL++L  +A     L M++ L+ NL++ H     ++HR    E++                 E  L ++++LQ H+  EV   A+ IN  L+
Sbjct:  253 QEMWLGFLKHKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFLTSACDVGGAISLLALNGLFILIHKHNLEYPDFYQRLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALL-MVLPLICNLLRRHPACRVMVHRPQGPELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSRAASVINQALS 461
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. UniProt/SwissProt
Match: sp|Q8BHY2|NOC4L_MOUSE (Nucleolar complex protein 4 homolog OS=Mus musculus OX=10090 GN=Noc4l PE=2 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 6.185e-22
Identity = 60/210 (28.57%), Postives = 102/210 (48.57%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNEMENQD--------------EEMLLDIKSLQNHFDIEVRNLANEINSKLN 897
            ++MWL FLK  +P  L   V++A+ D +L ++  P +  D +  + +      +++L  LF L+  + + Y   Y  LY LL   IF   + +RFF      LSS  +P  +   FAKRL++L  +A     L M++ L+ NL++ H     ++HR    E++                 E  L ++++LQ H+  EV   A+ IN  L+
Sbjct:  253 QEMWLGFLKHKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFLTSACDVGGAISLLALNGLFILIHKHNLEYPDFYQKLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALL-MVLPLICNLLRRHPACRVMVHRPQGPELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSKAASVINQVLS 461
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. UniProt/SwissProt
Match: sp|Q4VBT2|NOC4L_DANRE (Nucleolar complex protein 4 homolog OS=Danio rerio OX=7955 GN=noc4l PE=2 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 8.498e-22
Identity = 63/217 (29.03%), Postives = 111/217 (51.15%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE--------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNL 915
            EQMWL FL+  +P  +   +++ L + +L  + DP +  D +  +++      + +L  LF  +  + ++Y   Y  LY+LL   IF   + +RFF   +  LSS  +P  +   F KRL++L+ +A  T  L +++  + NL++ H     LIHR S+ +        ME +D       E  L +IK+LQNH   +V   A  IN  L+++ +++
Sbjct:  262 EQMWLLFLRYKLPGSMYKKILVILHESILPQMSDPKLMMDFLSAAYDIGGAISLSALNGLFVPIHEHNLDYPDFYKKLYNLLDPSIFHVKYRARFFHLANIFLSSTHLPVYLVAAFVKRLARLSLTAPPTALL-ILLPFICNLIRRHPSCRVLIHRPSAADEPCDDPYVMEEEDPAQCHALESSLWEIKTLQNHHHPDVSKAATMINEPLSAQEEDI 477
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. UniProt/SwissProt
Match: sp|Q6NU91|NOC4B_XENLA (Nucleolar complex protein 4 homolog B OS=Xenopus laevis OX=8355 GN=noc4l-b PE=2 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.306e-20
Identity = 60/212 (28.30%), Postives = 107/212 (50.47%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE-------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSR 903
            E++W+ FLK  +   L   V++ L + +L ++  P +  D +  +++      +++L  LF L+  + + Y   Y  LY LL+  +F   + +RFF   +  LSS  +P  +   FAKRL++L  +A     L M++  + NL++ H     LIHR S+ +       ME QD       E  L +++ LQ H+  +V   AN I+  L+++
Sbjct:  264 ERVWMSFLKHQLSVSLYKKVLLILHESILPHMSKPSLMIDFLTAAYDVGGAISLLALNGLFILIHQHNLEYPDFYKKLYSLLEPSVFHVKYRARFFHLANLFLSSTHLPVYLVAAFAKRLARLALTAPP-QVLLMIIPFICNLIRRHPACRVLIHRPSAGDLVTDPYIMEEQDPAKSQALESCLWELEVLQQHYHGDVVRAANVISRALSAQ 474
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. UniProt/SwissProt
Match: sp|Q5ZJC7|NOC4L_CHICK (Nucleolar complex protein 4 homolog OS=Gallus gallus OX=9031 GN=NOC4L PE=2 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 1.353e-20
Identity = 62/217 (28.57%), Postives = 105/217 (48.39%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE--------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNL 915
            E+MWL FLK  +P  L   V++ L D +L  +++P +  D +  ++       +++L  LF L+  + + Y   Y  LY LL   I+   + +RFF      LSS  +P  +   F KRLS+L  +A     L M++  + NL + H     L+HR +  +        ME ++       E  L +++SLQNH+  +V   A  +N  L+   D++
Sbjct:  245 ERMWLTFLKHQLPSGLYKKVLVILHDSILPYMNEPTLMIDFLTVAYGVGGAISLLALNGLFILIHQHNLEYPDFYKKLYSLLDPSIYHVKYRARFFHLADLFLSSSHLPAYLVAAFIKRLSRLALTAPPEALL-MVIPFICNLFRRHPACKVLMHRPNGPQDLSEDPYIMEQEEPSESRALESSLWELQSLQNHYHPDVAQAAAILNQSLSEIEDDI 460
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. TrEMBL
Match: A0A2D4N5Z5 (CBF domain-containing protein (Fragment) OS=Micrurus spixii OX=129469 PE=4 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 3.669e-23
Identity = 68/211 (32.23%), Postives = 109/211 (51.66%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHR-NSSNEMENQDEEM--------------LLDIKSLQNHFDIEVRNLANEINSKLN 897
            E++WL FLK  +P  L   V++ L D +L ++++P +  D +  +++      +++L  LF L+L + + Y   Y  LY LL   IF   + +RFF  +   LSS  +P  +   FAKRLS+L  +A     L +++  + NL++ H     LIHR NS  EM +   +M              L +IK+LQNH+  +V   A EIN  L+
Sbjct:  188 ERIWLGFLKYKLPGSLYKKVLVILHDSILPHLNEPTLLMDFLTVAYDVGGAISLLALNGLFVLILQHNLEYPDFYTKLYSLLDPSIFHVKYRARFFRLLDLFLSSSHLPAYLVAAFAKRLSRLALTAPPDGLL-IVIPFICNLLRRHPSCLVLIHRPNSPAEMPDDPYKMDEKDPLESRAVESSLWEIKTLQNHYHPDVAKAAEEINLPLS 397
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. TrEMBL
Match: A0A2D4N4Y7 (CBF domain-containing protein (Fragment) OS=Micrurus spixii OX=129469 PE=4 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 3.840e-23
Identity = 68/211 (32.23%), Postives = 109/211 (51.66%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHR-NSSNEMENQDEEM--------------LLDIKSLQNHFDIEVRNLANEINSKLN 897
            E++WL FLK  +P  L   V++ L D +L ++++P +  D +  +++      +++L  LF L+L + + Y   Y  LY LL   IF   + +RFF  +   LSS  +P  +   FAKRLS+L  +A     L +++  + NL++ H     LIHR NS  EM +   +M              L +IK+LQNH+  +V   A EIN  L+
Sbjct:  182 ERIWLGFLKYKLPGSLYKKVLVILHDSILPHLNEPTLLMDFLTVAYDVGGAISLLALNGLFVLILQHNLEYPDFYTKLYSLLDPSIFHVKYRARFFRLLDLFLSSSHLPAYLVAAFAKRLSRLALTAPPDGLL-IVIPFICNLLRRHPSCLVLIHRPNSPAEMPDDPYKMDEKDPLESRAVESSLWEIKTLQNHYHPDVAKAAEEINLPLS 391
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. TrEMBL
Match: A0A3P8Y1H0 (Nucleolar complex associated 4 homolog OS=Esox lucius OX=8010 PE=4 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 1.679e-22
Identity = 66/217 (30.41%), Postives = 113/217 (52.07%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE--------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNL 915
            E++WL FLK  +P  +   V++ L D +L +I +P +  D +  +++      +++L  LF L+  + ++Y   Y  LY+LL+  +F   + +RFF   +  LSS  +P  +   FAKRLS+L  +A     L M++  + NL++ H     LIHR S+ E        ME +D       E  L ++++LQNH+  +V   A  IN  L+ + D+ 
Sbjct:  266 ERLWLGFLKYKLPSSMYKMVLVILHDSILPHISNPTLMIDFLTAAYDVGGAISLLALNGLFVLIHQHNLDYPDFYKKLYNLLEPSVFHVKYRARFFHLANIFLSSTHLPVYLVAAFAKRLSRLALTAPPAALL-MVLPFICNLIRRHPACRVLIHRPSAAEQACDDPYMMEEEDPARCHALESSLWELQTLQNHYHPDVAKAAMAINKPLSQKEDDF 481
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. TrEMBL
Match: A0A3Q2C6W8 (Nucleolar complex associated 4 homolog OS=Cyprinodon variegatus OX=28743 PE=4 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 4.156e-22
Identity = 68/217 (31.34%), Postives = 116/217 (53.46%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSS-NE-------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNL 915
            E+MWL FLK  +P  +   V++ L D +L ++  P +  D +  +++      +++L  LF L+  + ++Y   Y  LY+LL+  +F   + +RFF   +  LSS  +P  +   FAKRL++L  +A  T  L +++  + NL++ H  A  LIH+ SS NE       ME +D       E  L +IK+LQ H+  +V   A  IN+ L+ + D++
Sbjct:  262 ERMWLGFLKYKLPNSMYKKVLVILHDSILPHMSKPTLMIDFLTAAYDVGGAISLLALNGLFVLIHQHNLDYPDFYKKLYNLLEPSVFHVKYTARFFHLANLFLSSSHLPVYLVAAFAKRLARLALTAPPTALL-IVLPFIYNLIRRHPSARVLIHKPSSENELLEDPYVMEEEDPALCHALESSLWEIKTLQKHYHPDVAKAAMLINTPLSEQEDDI 477
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. TrEMBL
Match: A0A1S3LFH6 (nucleolar complex protein 4 homolog OS=Salmo salar OX=8030 GN=noc4l PE=4 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 6.572e-22
Identity = 65/217 (29.95%), Postives = 112/217 (51.61%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE--------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNL 915
            E++WL FLK  +P  +   V++ L D +L +I +P V  D +  +++      +++L  LF L+  + ++Y   Y  LY LL+  +F   + +RFF   +  LSS  +P  +   FAKRLS+L  +A     L M++  + NL++ H     LIHR S+ +        ME +D       E  L ++++LQ H+  +V   A  IN  L+ + D++
Sbjct:  266 ERLWLGFLKYKLPSSMYKKVLVILHDSILPHISNPTVMIDFLTAAYDVGGAISLLALNGLFVLIHQHNLDYPDFYKKLYSLLEPSVFHVKYRARFFHLANLFLSSTHLPVYLVAAFAKRLSRLALTAPPAALL-MVLPFICNLIRRHPACRVLIHRPSAADEACDDPYLMEEEDPSQCHALESSLWELQTLQKHYHPDVAKAAMAINKPLSQQEDDI 481
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Cavefish
Match: noc4l (nucleolar complex associated 4 homolog [Source:NCBI gene;Acc:103043920])

HSP 1 Score: 103.605 bits (257), Expect = 5.212e-24
Identity = 63/213 (29.58%), Postives = 110/213 (51.64%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE--------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSR 903
            EQMWL FLK  +P  +   V++ L D ++ ++ DP +  D +  +++      +++L  LF L+  + ++Y   Y  LY+LL   +F   + +RFF   +  LSS  +P  +   F KRLS+L  +A  T  L +++  V NL++ H     LIHR S+ +        M+ +D       E  L ++++LQ H++ +V   A  IN  L+ +
Sbjct:  265 EQMWLTFLKYKLPGGMYKKVLVILHDTIMPHMSDPTLMIDFLTAAYDVGGAVSLLALNGLFVLIHKHNLDYPDFYKKLYNLLDPSVFHVKYKARFFHLANIFLSSSHLPVYLVAAFVKRLSRLALTAPPTALL-IVLPFVYNLIRRHPSCRVLIHRPSAADELCNDPYLMDEEDPTKCHALESSLWELQTLQKHYNPDVSKAAKAINEPLSRQ 476
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Yeast
Match: NOC4 (Nucleolar protein; forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006348])

HSP 1 Score: 51.6026 bits (122), Expect = 9.940e-8
Identity = 39/188 (20.74%), Postives = 89/188 (47.34%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSF---EKSRESGIV---SLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNS--SNEMENQDEEMLLDIKSLQNHF 849
            E+ WL  L   +       +++ L   ++ +   P    D +  S+     ++ +G+V   +L  LF+L+    + Y   Y  LY ++  D+    + +RFF  +   LSS  +  ++   F K+L++LT  +  +  +  ++  + NL++ H     ++H  +  SN  +  D+  + ++K+L+ ++
Sbjct:  258 EKNWLSLLNGQLSLQQYKSILLILHKRIIPHFHTPTKLMDFLTDSYNLQSSNKNAGVVPILALNGLFELMKRFNLEYPNFYMKLYQIINPDLMHVKYRARFFRLMDVFLSSTHLSAHLVASFIKKLARLTLESPPSAIV-TVIPFIYNLIRKHPNCMIMLHNPAFISNPFQTPDQ--VANLKTLKENY 442
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Nematostella
Match: EDO43971 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX49])

HSP 1 Score: 90.8929 bits (224), Expect = 4.480e-20
Identity = 61/217 (28.11%), Postives = 99/217 (45.62%), Query Frame = 1 
Query:  319 WLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNEM---ENQD---------------------EEMLLDIKSLQNHFDIEVRNLANEINSKLN 897
            WL     P+ +     V+++L + V+ +++DP +  D +  S+       +++L  LF L+  + ++Y   Y  LY LLQ  IF + + SRFF  +   LSS  +P  +   F KRLS L  SA  +  + ++V  V N++K H     LIHR  +  +   EN D                     +  L ++KSLQ H+  EV  L   +   L 
Sbjct:  260 WLGLTSLPLTQDTHKKVLLSLHNNVIPHMNDPKLLMDYLTDSYNIGGAISLLALNGLFILIHKHNLDYPEFYKKLYGLLQPGIFHAKYLSRFFHLLDLFLSSTHLPAYLVAAFLKRLSGLALSAPPSCVM-LVVTFVANMLKRHPSCQVLIHRKKAGPLFLTENSDTLASEDPFLSEEEDPAKCNALQSSLWELKSLQQHYYPEVSPLVESLQKPLG 475
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Medaka
Match: noc4l (nucleolar complex associated 4 homolog [Source:NCBI gene;Acc:101174683])

HSP 1 Score: 99.7525 bits (247), Expect = 1.250e-22
Identity = 60/217 (27.65%), Postives = 113/217 (52.07%), Query Frame = 1 
Query:  310 EQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE--------MENQD-------EEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNL 915
            E+MWL FLK  +P  +   +++ L D +L ++  P +  D +  ++E      +++L  LF L+  + ++Y   Y  LY+LL+  +F   + +RFF   +  LSS  +P  +   F KRL++L  +A  T  L +++  + NL++ H     L+H+ S+ +        M+ +D       E  L +IK+LQ H+  +V   A  IN+ L+ + +++
Sbjct:  266 EKMWLGFLKYKLPSNMYKKLLVILHDSILPHMSKPALMIDFLTAAYEVGGAISLLALNGLFVLIHQHNLDYPDFYKKLYNLLEPTVFHVKYRARFFHLANLFLSSSHLPLYLVAAFTKRLARLALTAPPTGLL-IVLPFIYNLIRRHPSCRVLLHKPSTEDEPVEDPYLMDEEDPAQCRALESSLWEIKTLQKHYHPDVAKAAMMINTPLSEQEEDI 481
[Close]
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Planmine SMEST
Match: SMESG000074718.1 (SMESG000074718.1)

HSP 1 Score: 670.618 bits (1729), Expect = 0.000e+0
Identity = 355/356 (99.72%), Postives = 355/356 (99.72%), Query Frame = 1 
Query:    1 MKSKPDVKYDAENINKLLESVFIIQKTNIDDILSKLNYVDICYYTIKFLNEKLSSPKGFSYDFYEKVFNVAMNVLGDDSGRXXXXXXXXXXXXXXXXXXXXXHEQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNEMENQDEEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNLIPSQSIENAKNKTNKCRERIQKALSALMGNNCSLPDLQPISNIRNVSMKLF 1068
            MKSKPDVKYDAENINKLLESVFIIQKTNIDDILSKLNYVDICYYTIKFLNEKLSSPKGFSYDFYEKVFNVAMNVLGDDSGRKYLQKENKKNKKMKVCNVLNMHEQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNE ENQDEEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNLIPSQSIENAKNKTNKCRERIQKALSALMGNNCSLPDLQPISNIRNVSMKLF
Sbjct:    1 MKSKPDVKYDAENINKLLESVFIIQKTNIDDILSKLNYVDICYYTIKFLNEKLSSPKGFSYDFYEKVFNVAMNVLGDDSGRKYLQKENKKNKKMKVCNVLNMHEQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFEKSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFDDISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWHCGATSLIHRNSSNETENQDEEMLLDIKSLQNHFDIEVRNLANEINSKLNSRIDNLIPSQSIENAKNKTNKCRERIQKALSALMGNNCSLPDLQPISNIRNVSMKLF 356
The following BLAST results are available for this feature:
BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
NOC4L2.161e-1927.62nucleolar complex associated 4 homolog [Source:HGN... [more]
NOC4L2.161e-1927.62nucleolar complex associated 4 homolog [Source:HGN... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
T20B12.34.753e-1224.64pep chromosome:WBcel235:III:7382115:7383906:1 gene... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CG28753.407e-1528.43gene:FBgn0029672 transcript:FBtr0070586[more]
CG28753.526e-1528.43gene:FBgn0029672 transcript:FBtr0333793[more]
CG28753.526e-1528.43gene:FBgn0029672 transcript:FBtr0070587[more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
noc4l7.582e-2529.95nucleolar complex associated 4 homolog [Source:NCB... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
noc4l1.122e-2128.77nucleolar complex associated 4 homolog [Source:NCB... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Noc4l8.842e-2328.57NOC4 like [Source:MGI Symbol;Acc:MGI:2140843][more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5I0I8|NOC4L_RAT3.610e-2228.57Nucleolar complex protein 4 homolog OS=Rattus norv... [more]
sp|Q8BHY2|NOC4L_MOUSE6.185e-2228.57Nucleolar complex protein 4 homolog OS=Mus musculu... [more]
sp|Q4VBT2|NOC4L_DANRE8.498e-2229.03Nucleolar complex protein 4 homolog OS=Danio rerio... [more]
sp|Q6NU91|NOC4B_XENLA1.306e-2028.30Nucleolar complex protein 4 homolog B OS=Xenopus l... [more]
sp|Q5ZJC7|NOC4L_CHICK1.353e-2028.57Nucleolar complex protein 4 homolog OS=Gallus gall... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2D4N5Z53.669e-2332.23CBF domain-containing protein (Fragment) OS=Micrur... [more]
A0A2D4N4Y73.840e-2332.23CBF domain-containing protein (Fragment) OS=Micrur... [more]
A0A3P8Y1H01.679e-2230.41Nucleolar complex associated 4 homolog OS=Esox luc... [more]
A0A3Q2C6W84.156e-2231.34Nucleolar complex associated 4 homolog OS=Cyprinod... [more]
A0A1S3LFH66.572e-2229.95nucleolar complex protein 4 homolog OS=Salmo salar... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
noc4l5.212e-2429.58nucleolar complex associated 4 homolog [Source:NCB... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
NOC49.940e-820.74Nucleolar protein; forms a complex with Nop14p tha... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO439714.480e-2028.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
noc4l1.250e-2227.65nucleolar complex associated 4 homolog [Source:NCB... [more]
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BLAST of Phosphatidylinositol 4-kinase type 2-beta vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000074718.10.000e+099.72SMESG000074718.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005458 ID=SMED30005458|Name=Phosphatidylinositol 4-kinase type 2-beta|organism=Schmidtea mediterranea sexual|type=transcript|length=1083bp
ATGAAATCAAAACCTGATGTGAAATATGATGCTGAAAACATTAATAAATT
GTTGGAATCAGTGTTCATTATTCAGAAAACTAACATTGACGATATATTGT
CTAAATTAAATTATGTTGACATTTGCTATTATACCATTAAATTCTTAAAT
GAAAAGTTATCCAGTCCAAAGGGGTTCTCTTATGACTTTTACGAGAAAGT
TTTCAATGTTGCTATGAATGTTTTGGGCGATGATTCAGGAAGAAAGTATT
TACAAAAAGAAAATAAAAAAAATAAAAAAATGAAAGTCTGCAATGTACTA
AATATGCACGAGCAAATGTGGCTTAAATTTTTAAAATCTCCAATGCCGGA
GCCTTTAAGACTCGATGTAATAATTGCTTTAGGTGACGAAGTTTTGGATA
ATATTGATGATCCAGGTGTCTTTGCAGACATTATTATTAAATCATTTGAA
AAAAGTAGAGAATCCGGAATTGTCTCTTTAAGAGCATTGTTTAAATTATT
ACTTAACAATAAAATTAACTATACTCCAGTTTATGATGTTTTATACGATT
TATTACAAGAAGATATTTTTAAATCTCCATTTTGTTCACGATTTTTCGAT
GATATCAGTTCGATTCTTTCATCCAAAAGTATGCCCCATAACATAGCAGT
AAAATTCGCTAAACGTCTCTCAAAATTGACTCAATCCGCCTCGTCTACTC
ACTATTTACCGATGATGGTCCGATTGGTTGTCAATCTAATGAAGTGGCAC
TGTGGAGCGACAAGCCTGATTCACCGAAACTCATCGAATGAAATGGAAAA
TCAAGACGAAGAAATGCTTCTGGATATAAAATCCCTTCAAAATCATTTCG
ATATCGAAGTCAGGAATTTGGCCAATGAAATCAACAGCAAATTGAACAGT
CGTATTGACAATTTGATTCCGTCACAAAGCATTGAGAATGCTAAAAATAA
AACGAACAAATGTCGAGAACGCATCCAAAAGGCTCTCAGTGCGTTAATGG
GAAACAATTGCAGCCTGCCGGACTTGCAACCAATCAGCAACATTAGAAAT
GTTTCAATGAAATTGTTTTAAAATATATTTCAT
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protein sequence of SMED30005458-orf-1

>SMED30005458-orf-1 ID=SMED30005458-orf-1|Name=SMED30005458-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=357bp
MKSKPDVKYDAENINKLLESVFIIQKTNIDDILSKLNYVDICYYTIKFLN
EKLSSPKGFSYDFYEKVFNVAMNVLGDDSGRKYLQKENKKNKKMKVCNVL
NMHEQMWLKFLKSPMPEPLRLDVIIALGDEVLDNIDDPGVFADIIIKSFE
KSRESGIVSLRALFKLLLNNKINYTPVYDVLYDLLQEDIFKSPFCSRFFD
DISSILSSKSMPHNIAVKFAKRLSKLTQSASSTHYLPMMVRLVVNLMKWH
CGATSLIHRNSSNEMENQDEEMLLDIKSLQNHFDIEVRNLANEINSKLNS
RIDNLIPSQSIENAKNKTNKCRERIQKALSALMGNNCSLPDLQPISNIRN
VSMKLF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:00044301-phosphatidylinositol 4-kinase activity
GO:0016301kinase activity
Vocabulary: biological process
TermDefinition
GO:0016310phosphorylation
GO:0046854phosphatidylinositol phosphorylation
GO:0042254ribosome biogenesis
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000044cephalic ganglia
PLANA:0000062esophagus
PLANA:0000081pharynx pouch
PLANA:0000097ventral nerve cord
PLANA:0000142posterior region of the whole animal
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR027193Noc4
IPR005612CCAAT-binding_factor
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 311..331
IPR005612CCAAT-binding factorPFAMPF03914CBFcoord: 157..288
e-value: 4.7E-9
score: 36.5
IPR027193Nucleolar complex protein 4PANTHERPTHR12455NUCLEOLAR COMPLEX PROTEIN 4coord: 16..305