CIP29
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30005428 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of CIP29 vs. Ensembl Human
Match: SARNP (SAP domain containing ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:24432]) HSP 1 Score: 71.2478 bits (173), Expect = 4.676e-14 Identity = 77/248 (31.05%), Postives = 118/248 (47.58%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGL 784 +L KLK+ +L+++C GL G K +LI R+Q L+ + + D +LGD T E + + I+ P+ E EEP K +D+ K+ K+ T + + ++ Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ TS G + KK RA RFG+ Sbjct: 7 ELHKLKLAELKQECLARGLETKGIKQDLIHRLQ------------------AYLEEHAEEEANEED---VLGDETEEEETK----------PIELPVKE-------EEPPEKT--VDVAAEKKVVKI-TSEIPQTERMQKRAERFNVPVSL--ESKKAARAARFGISSVPTKGLSSDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTS--SAGTGTTEDTEAKKRKRAERFGI 209
BLAST of CIP29 vs. Ensembl Human
Match: SARNP (SAP domain containing ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:24432]) HSP 1 Score: 71.2478 bits (173), Expect = 4.676e-14 Identity = 77/248 (31.05%), Postives = 118/248 (47.58%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGL 784 +L KLK+ +L+++C GL G K +LI R+Q L+ + + D +LGD T E + + I+ P+ E EEP K +D+ K+ K+ T + + ++ Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ TS G + KK RA RFG+ Sbjct: 7 ELHKLKLAELKQECLARGLETKGIKQDLIHRLQ------------------AYLEEHAEEEANEED---VLGDETEEEETK----------PIELPVKE-------EEPPEKT--VDVAAEKKVVKI-TSEIPQTERMQKRAERFNVPVSL--ESKKAARAARFGISSVPTKGLSSDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTS--SAGTGTTEDTEAKKRKRAERFGI 209
BLAST of CIP29 vs. Ensembl Human
Match: SARNP (SAP domain containing ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:24432]) HSP 1 Score: 65.855 bits (159), Expect = 3.839e-12 Identity = 74/246 (30.08%), Postives = 115/246 (46.75%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARF 778 +L KLK+ +L+++C GL G K +LI R+Q L+ + + D +LGD T E + + I+ P+ E EEP K +D+ K+ K+ T + + ++ Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ TS S G D + + RF Sbjct: 7 ELHKLKLAELKQECLARGLETKGIKQDLIHRLQ------------------AYLEEHAEEEANEED---VLGDETEEEETK----------PIELPVKE-------EEPPEKT--VDVAAEKKVVKI-TSEIPQTERMQKRAERFNVPVSL--ESKKAARAARFGISSVPTKGLSSDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTS----SAGTGTTEDTEVKIYLERF 205
BLAST of CIP29 vs. Ensembl Human
Match: AC023055.1 (novel protein) HSP 1 Score: 67.0106 bits (162), Expect = 9.325e-12 Identity = 74/243 (30.45%), Postives = 114/243 (46.91%), Query Frame = 2 Query: 71 KVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGL 784 K+ +L+++C GL G K +LI R+Q L+ + + D +LGD T E + + I+ P+ E EEP K +D+ K+ K+ T + + ++ Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ TS G + KK RA RFG+ Sbjct: 325 KLAELKQECLARGLETKGIKQDLIHRLQ------------------AYLEEHAEEEANEED---VLGDETEEEETKP----------IELPVKE-------EEPPEKT--VDVAAEKKVVKI-TSEIPQTERMQKRAERFNVPV--SLESKKAARAARFGISSVPTKGLSSDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTS--SAGTGTTEDTEAKKRKRAERFGI 522
BLAST of CIP29 vs. Ensembl Zebrafish
Match: sarnp (SAP domain containing ribonucleoprotein [Source:ZFIN;Acc:ZDB-GENE-050522-161]) HSP 1 Score: 74.3294 bits (181), Expect = 2.335e-15 Identity = 52/109 (47.71%), Postives = 66/109 (60.55%), Query Frame = 2 Query: 470 QDRAARFGI-ITNDTEENKKLARAQRFGLDVSKSNGDVT----VDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFG 781 Q RA RF + +T D NKK ARA RFG+ +S+ + VD+E LKKR ERFG++VS K D+EK KR ERFG+ TS S GG + ++ KK RA RFG Sbjct: 99 QKRAERFNVPLTGD---NKKAARAARFGVTAPESSKGASTKTNVDVEVLKKRAERFGMNVSSVSKKVEDDEKLKKRKERFGIVTS--ASSSGGGDDSEAKKRKRAERFG 202
BLAST of CIP29 vs. Ensembl Xenopus
Match: sarnp (SAP domain containing ribonucleoprotein [Source:NCBI gene;Acc:549238]) HSP 1 Score: 70.4774 bits (171), Expect = 7.670e-14 Identity = 51/119 (42.86%), Postives = 69/119 (57.98%), Query Frame = 2 Query: 452 SEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVT-----VDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDD---KKAVRAARFGL 784 SE K Q RA RF + + ++KK ARA RFGL S G+++ V ++KLK+R +RFG+SVS K+ D+EK KR ERFG+ TS ++ DD KK RA RFG+ Sbjct: 97 SETDKLQKRAERFNVPA--SVDSKKAARAIRFGLSTSDKKGEISDAKSPVSMDKLKERAQRFGLSVSPVSKKSEDDEKLKKRKERFGIVTS-------SASVTDDTEAKKRKRAERFGI 206
BLAST of CIP29 vs. Ensembl Xenopus
Match: sarnp (SAP domain containing ribonucleoprotein [Source:NCBI gene;Acc:549238]) HSP 1 Score: 55.4546 bits (132), Expect = 1.650e-8 Identity = 71/220 (32.27%), Postives = 99/220 (45.00%), Query Frame = 2 Query: 80 DLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQ--VVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKV------LTIDNSEEKKKQDRAARFGIITN--DTEENKKLARAQRFGLDVSKSNGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTS 709 +L+++C GL + GNKS+LISR+Q E +E NE ++LGE + Q V+ V E+ EP + P T+ E+ KI ETDK+ + S + KK RA R GII E Q F S+ V ++KLK+R +RFG+SVS K+ D+EK KR ERFG+ TS Sbjct: 24 ELKQECLARGLEVKGNKSDLISRLQAYIEEHAEEEA-NEEDVLGEETEEEEQKSSVAAVKEE--------------------------EP-DDKPADTNAEKKLVKIS----SSASETDKLQKRAERFNVPASVDSKKAARAIRLGIIWFIFKLTELYFHINLQWFIFSGEISDAKSPVSMDKLKERAQRFGLSVSPVSKKSEDDEKLKKRKERFGIVTS 211
BLAST of CIP29 vs. Ensembl Mouse
Match: Sarnp (SAP domain containing ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1913368]) HSP 1 Score: 76.6406 bits (187), Expect = 3.170e-16 Identity = 79/249 (31.73%), Postives = 120/249 (48.19%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLT-IDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGL 784 +L KLK+ +L+++C GL G K +LI+R+Q + +E +E+ +LGD T E + + I+ P+ E EEP K +DM K+ K+ + I +E + Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ TS G + KK RA RFG+ Sbjct: 7 ELHKLKLAELKQECLARGLETKGIKQDLINRLQAYLEDHAEE---------------------EANEEDVLGDETEEEEPKP----------IELPVKE-------EEPPEKA--VDMASEKKVVKITSGIPQTE--RMQKRAERFNVPV--SLESKKAARAARFGISSVPTKGLSSDTKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTSSA--GTGTTEDTEAKKRKRAERFGI 209
BLAST of CIP29 vs. Ensembl Mouse
Match: Sarnp (SAP domain containing ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1913368]) HSP 1 Score: 63.1586 bits (152), Expect = 4.382e-12 Identity = 46/113 (40.71%), Postives = 63/113 (55.75%), Query Frame = 2 Query: 470 QDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDD---KKAVRAARFGL 784 Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ V S G +D KK RA RFG+ Sbjct: 21 QKRAERFNVPV--SLESKKAARAARFGISSVPTKGLSSDTKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGI-----VTSSAGTGTTEDTEAKKRKRAERFGI 126 HSP 2 Score: 59.6918 bits (143), Expect = 7.322e-11 Identity = 46/101 (45.54%), Postives = 58/101 (57.43%), Query Frame = 2 Query: 437 LTIDNSEEKKKQDRAARFGI-------ITNDTEENKKL----ARAQRFGLDVSKSNGDVTVDIEKLKKREERFGVSVSDKLSKAAD--EEKKLKRAERFGV 700 + S E KK RAARFGI +++DT+ L RAQRFGL+VS S + D EKLKKR+ERFG+ S + + E KK KRAERFG+ Sbjct: 27 FNVPVSLESKKAARAARFGISSVPTKGLSSDTKPMVNLDKLKERAQRFGLNVS-SISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEAKKRKRAERFGI 126
BLAST of CIP29 vs. UniProt/SwissProt
Match: sp|Q9D1J3|SARNP_MOUSE (SAP domain-containing ribonucleoprotein OS=Mus musculus OX=10090 GN=Sarnp PE=1 SV=3) HSP 1 Score: 76.6406 bits (187), Expect = 2.218e-15 Identity = 79/249 (31.73%), Postives = 120/249 (48.19%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLT-IDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGL 784 +L KLK+ +L+++C GL G K +LI+R+Q + +E +E+ +LGD T E + + I+ P+ E EEP K +DM K+ K+ + I +E + Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ TS G + KK RA RFG+ Sbjct: 7 ELHKLKLAELKQECLARGLETKGIKQDLINRLQAYLEDHAEE---------------------EANEEDVLGDETEEEEPKP----------IELPVKE-------EEPPEKA--VDMASEKKVVKITSGIPQTE--RMQKRAERFNVPV--SLESKKAARAARFGISSVPTKGLSSDTKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTSSA--GTGTTEDTEAKKRKRAERFGI 209
BLAST of CIP29 vs. UniProt/SwissProt
Match: sp|Q498U4|SARNP_RAT (SAP domain-containing ribonucleoprotein OS=Rattus norvegicus OX=10116 GN=Sarnp PE=1 SV=3) HSP 1 Score: 73.559 bits (179), Expect = 2.956e-14 Identity = 79/249 (31.73%), Postives = 120/249 (48.19%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLT-IDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGL 784 +L KLK+ +L+++C GL G K +LI+R+Q L+ + + D +LGD T E + + I+ P+ E EEP K+ +DM K+ K+ + I +E + Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ TS G + KK RA RFG+ Sbjct: 7 ELHKLKLAELKQECLARGLETKGIKQDLINRLQ------------------AYLEEHAEEEANEED---VLGDETEEEEPK----------PIELPVKE-------EEPPEKV--VDMASEKKVVKITSGIPQTE--RMQKRAERFNVPVSL--ESKKAARAARFGISSVPTKGLSSDTKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTS--SAGTGTTEDTEAKKRKRAERFGI 209
BLAST of CIP29 vs. UniProt/SwissProt
Match: sp|Q5R4V4|SARNP_PONAB (SAP domain-containing ribonucleoprotein OS=Pongo abelii OX=9601 GN=SARNP PE=2 SV=3) HSP 1 Score: 71.2478 bits (173), Expect = 2.245e-13 Identity = 77/248 (31.05%), Postives = 118/248 (47.58%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGL 784 +L KLK+ +L+++C GL G K +LI R+Q L+ + + D +LGD T E + + I+ P+ E EEP K +D+ K+ K+ T + + ++ Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ TS G + KK RA RFG+ Sbjct: 7 ELHKLKLAELKQECLARGLETKGIKQDLIHRLQ------------------AYLEEHAEEEANEED---VLGDETEEEETK----------PIELPVKE-------EEPPEKT--VDVAAEKKVVKI-TSEIPQTERMQKRAERFNVPVSL--ESKKAARAARFGISSVPTKGLSSDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTS--SAGTGTTEDTEAKKRKRAERFGI 209
BLAST of CIP29 vs. UniProt/SwissProt
Match: sp|P82979|SARNP_HUMAN (SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3) HSP 1 Score: 71.2478 bits (173), Expect = 2.245e-13 Identity = 77/248 (31.05%), Postives = 118/248 (47.58%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNG-----DVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGL 784 +L KLK+ +L+++C GL G K +LI R+Q L+ + + D +LGD T E + + I+ P+ E EEP K +D+ K+ K+ T + + ++ Q RA RF + + E+KK ARA RFG+ + G V+++KLK+R +RFG++VS K+ D+EK KR ERFG+ TS G + KK RA RFG+ Sbjct: 7 ELHKLKLAELKQECLARGLETKGIKQDLIHRLQ------------------AYLEEHAEEEANEED---VLGDETEEEETK----------PIELPVKE-------EEPPEKT--VDVAAEKKVVKI-TSEIPQTERMQKRAERFNVPVSL--ESKKAARAARFGISSVPTKGLSSDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTS--SAGTGTTEDTEAKKRKRAERFGI 209
BLAST of CIP29 vs. UniProt/SwissProt
Match: sp|O74871|YCW3_SCHPO (Uncharacterized protein C31H12.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPCC31H12.03c PE=1 SV=1) HSP 1 Score: 53.9138 bits (128), Expect = 3.532e-7 Identity = 58/227 (25.55%), Postives = 98/227 (43.17%), Query Frame = 2 Query: 50 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPI------KETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSI 712 M D LKV +LR+K + GLS GNK+EL+SR+ + + N A LG+L + ++D+ GD ++ D + TDV +P+ K P KE + +++ + S+ + + EE+++ + + S+ DV + EKL +R +RFG+ V D ++ KK RA RFG+Q + Sbjct: 1 MSDYKSLKVAELREKLAEKGLSTAGNKAELVSRLTAATESNDENTSNNNATDLGDL--------APPEDDIDWGD-----------------MENDT------ISTDVNKPAEPESKETSAPAAAVEIEKENESIISKETSQAPE----------TSTGAEEHQETTEESKQSVSNEVSSPDVAKEQEKLIQRAKRFGIPVDD------EQIKKAARAARFGIQQPL 180
BLAST of CIP29 vs. TrEMBL
Match: H9CXU0 (CIP29 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 479.559 bits (1233), Expect = 1.450e-169 Identity = 261/261 (100.00%), Postives = 261/261 (100.00%), Query Frame = 2 Query: 50 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGLNTDEEKKKARAARFGN 832 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTSESKEEKNENNLSSILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGLNTDEEKKKARAARFGN Sbjct: 1 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTSESKEEKNENNLSSILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGLNTDEEKKKARAARFGN 261
BLAST of CIP29 vs. TrEMBL
Match: A0A3Q0KI39 (SAP domain-containing protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 113.62 bits (283), Expect = 7.178e-26 Identity = 109/300 (36.33%), Postives = 155/300 (51.67%), Query Frame = 2 Query: 50 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVL----NEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKET----DKVL----TIDNSEEKKKQD------------RAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVTVD--------IEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDD-KKAVRAARFGLN-------TDEEKKKARAARFG 829 +EDL KLK++DL+K CK+ L TG K ELISRI + G++ VL +EAELLG+ + DS V+ + ST+ + + N+N S L PV+T + K P ++ P K++ +KVL T D+S + K++ R RF +++ K LARA+RFGL +S + V ++ +EKLKKR ERFGV+ S L K D E+K KR E+FG S S G +ND+ K++RA +FGLN +D EK R ARFG Sbjct: 8 VEDLHKLKLSDLKKICKENKLPSTGTKVELISRITEMH---GNKFVLLQPGDEAELLGDDEDGDSNHVN-------ISHSTTTTMDCSNDNGSPSGLNF-------PVVTANKTVGRKRPASELTPEKDSMTSGEKVLKVAHTTDDSHDNAKEEVTNLSDSERLVCRTKRFM-----SDDEKTLARAKRFGLPISNNINTVCLNNTSTKLDELEKLKKRAERFGVTTSKTLEKLTDLERKAKRLEKFGKPLS---SSSGNTQMNDELAKSIRAQKFGLNLSNNNSISDAEKLSKRQARFG 282
BLAST of CIP29 vs. TrEMBL
Match: G4VN50 (SAP domain-containing protein OS=Schistosoma mansoni OX=6183 GN=Smp_078090.1 PE=4 SV=1) HSP 1 Score: 110.538 bits (275), Expect = 1.061e-24 Identity = 108/300 (36.00%), Postives = 155/300 (51.67%), Query Frame = 2 Query: 50 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVL----NEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKET----DKVL----TIDNSEEKKKQD------------RAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVTVD--------IEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDD-KKAVRAARFGLN-------TDEEKKKARAARFG 829 +EDL KLK++DL+K CK+ L TG K ELISRI + G++ VL +EAELLG+ + DS V+ + ST+ + + N+N S L PV+T + K P ++ P K++ +KVL T D+S + K++ R RF +++ K LARA+RFGL +S + V ++ +EKLKKR ERFGV+ S L K D E+K KR E+FG + S G +ND+ K++RA +FGLN +D EK R ARFG Sbjct: 8 VEDLHKLKLSDLKKICKENKLPSTGTKVELISRITEMH---GNKFVLLQPGDEAELLGDDEDGDSNHVN-------ISHSTTTTMDCSNDNGSPSGLNF-------PVVTANKTVGRKRPASELTPEKDSMTSGEKVLKVAHTTDDSHDNAKEEVTNLSDSERLVCRTKRFM-----SDDEKTLARAKRFGLPISNNINTVCLNNTSTKLDELEKLKKRAERFGVTTSKTLEKLTDLERKAKRLEKFG-KPLSSSSSSGNTQMNDELAKSIRAQKFGLNLSNNNSISDAEKLSKRQARFG 284
BLAST of CIP29 vs. TrEMBL
Match: C1LGG2 (DNA-binding SAP,domain-containing protein OS=Schistosoma japonicum OX=6182 GN=EWB00_003880 PE=2 SV=1) HSP 1 Score: 106.686 bits (265), Expect = 2.780e-23 Identity = 98/291 (33.68%), Postives = 143/291 (49.14%), Query Frame = 2 Query: 50 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVL----NEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKET---DKVLTIDNSEEKKKQDRAARFGIITNDTE------------ENKKLARAQRFGLDVSKSNGDVTV----DIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDD-KKAVRAARFGLN-------TDEEKKKARAARFG 829 +EDL KLK++DL+K CK+ LS TG K ELISRI + G++ VL +EAELLG+ + DS V D + ++ + PV++ + S K P ++ P K+ +K L I ++ E + + +D+E E K LARA+RFGL ++ N + ++EKLK+R ERFG + S L D E+K KR E+FG V S G ++LND+ K++RA +FGL +D EK R ARFG Sbjct: 9 IEDLHKLKLSDLKKICKENKLSSTGTKVELISRITEIH---GNKFVLLQPGDEAELLGDDEDGDSNNVDISHTDTMDCNNNASLNSVNF-----------------PVVSPAKNLSRKRPASELTPEKDLMKDEKALKIAHTIEDSHVSNSKEEMTMLSDSEHLTCRIKRFTTDEEKSLARAKRFGLPINSHNINTATSKSDELEKLKRRAERFGQTTSKTLEMINDLERKAKRLEKFGT----PVSSSGKIHLNDELAKSIRAQKFGLVLSSNDSLSDAEKLSRRQARFG 275
BLAST of CIP29 vs. TrEMBL
Match: C1L4Y5 (DNA-binding SAP,domain-containing protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1) HSP 1 Score: 104.375 bits (259), Expect = 2.053e-22 Identity = 97/291 (33.33%), Postives = 142/291 (48.80%), Query Frame = 2 Query: 50 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVL----NEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKET---DKVLTIDNSEEKKKQDRAARFGIITNDTE------------ENKKLARAQRFGLDVSKSNGDVTV----DIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDD-KKAVRAARFGLN-------TDEEKKKARAARFG 829 +EDL KLK++DL+K CK+ LS TG K ELISRI + G++ VL +EAELLG+ + DS V D + ++ + PV++ + S K P ++ P K+ +K L I ++ E + + +D+E E K LARA+RFGL ++ N + ++EKLK+R ERFG + S L D E+K KR E+FG V S G ++LND+ K++RA +FGL +D K R ARFG Sbjct: 9 IEDLHKLKLSDLKKICKENKLSSTGTKVELISRITEIH---GNKFVLLQPGDEAELLGDDEDGDSNNVDISHTDTMDCNNNASLNSVNF-----------------PVVSPAKNLSRKRPASELTPEKDLMKDEKALKIAHTIEDSHASNSKEEMTMLSDSEHLTCRIKRFTTDEEKSLARAKRFGLPINSHNINTATSKSDELEKLKRRAERFGQTTSKTLEMINDLERKAKRLEKFGT----PVSSSGKIHLNDELAKSIRAQKFGLVLSSNDSLSDAGKLSRRQARFG 275
BLAST of CIP29 vs. Ensembl Cavefish
Match: sarnp (SAP domain containing ribonucleoprotein [Source:NCBI gene;Acc:103027166]) HSP 1 Score: 73.9442 bits (180), Expect = 2.295e-15 Identity = 84/267 (31.46%), Postives = 118/267 (44.19%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSN--------GDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGLNTDEEKKKARAARFGN 832 +L KLK+ +L+++C GL I GNK +LI+R+Q E E +NE E+LGE S +Q E + EP + +P K K+ T +S +++ Q RA RF + +T +NKK ARA RFG+ + S VD+E LKKR ERFG++VS K ++EK KR ERFG+QT +D +A KK+ RA RFGN Sbjct: 6 ELQKLKLAELKQECSLRGLDIKGNKGDLIARLQQYLEE--HEEDVNEEEVLGEFTEEAS-------------------------PKAEEAVQEQETVVEP----------------ETEPKKAVVKI-TAPSSGDERLQKRAERFNL--PETLDNKKAARAARFGIPATASAPSKGASAMSKTNVDVEVLKKRAERFGMNVSSVSKKVEEDEKLKKRKERFGIQTGAAAAG----AGAEDSEA-------------KKRKRAERFGN 209
BLAST of CIP29 vs. Ensembl Sea Lamprey
Match: sarnp (SAP domain containing ribonucleoprotein [Source:ZFIN;Acc:ZDB-GENE-050522-161]) HSP 1 Score: 47.7506 bits (112), Expect = 8.740e-7 Identity = 57/145 (39.31%), Postives = 76/145 (52.41%), Query Frame = 2 Query: 371 VEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVT-------VDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGL 784 VE+P+ K K D VLT SE ++ Q RA RF + N E+ KK ARA RFG+ +++N V+ VD KL++R +RFGV+VS K E K KR ERFGV T+ + + KK RA RFG+ Sbjct: 94 VEKPAVK---------KVQDVVLT---SEAERLQTRAKRFNVEMN--EQAKKAARAARFGIVTTETNKAVSHRMTSVQVDTTKLQERAKRFGVNVSTVAQKIEVEGKLKKRKERFGVVTAAAAVATEDTEI---KKLKRAERFGI 221
BLAST of CIP29 vs. Ensembl Nematostella
Match: EDO48904 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHS5]) HSP 1 Score: 68.9366 bits (167), Expect = 3.158e-13 Identity = 92/281 (32.74%), Postives = 136/281 (48.40%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDST----XXXXXXXXXXXXXXILQIDEPLS------EPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDN--SEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDV----------SKSNGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGLNTDEEKKKARAARFGN 832 ++ KLKV +L+K+ + GL++ GNKS+L +R+ + G L+E E +++G D + DED +L D + + E SS L DE S E P+ + +E + I T LT+++ SE ++K R RFG +E ++KLARA+RFG+++ + + +D+ KLKKR ERFGV VS +S ++EK LKR ERFGV T V AA + E KKK RA RF N Sbjct: 6 NVKKLKVAELKKELQQHGLTVKGNKSDLQARLTEFLQ--GQGVALHEGE---DVEGDDDLDNDDHDEDDVLADDSVDDLVAEESLSEEKKESSSLSADEVKSGKTEKIENPLPANGKEKKSSI----------TAAKLTVNSAASENERKLQRMKRFG--GPVSENDRKLARAERFGINLKETGKQDVNTTSTTQATPIDVNKLKKRAERFGV-VSPAVSNIVEKEKLLKRKERFGVTT------------------VAAA--TADPLEIKKKKRAERFSN 248
BLAST of CIP29 vs. Ensembl Medaka
Match: sarnp (SAP domain containing ribonucleoprotein [Source:NCBI gene;Acc:101168041]) HSP 1 Score: 81.2629 bits (199), Expect = 8.326e-18 Identity = 86/257 (33.46%), Postives = 114/257 (44.36%), Query Frame = 2 Query: 56 DLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQ------PIKETDKVLTIDN--SEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKS-------NGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFG 781 +L KLK+ +LR++C GL GNK ELI+R+Q + L E E +VD D +L + T P T VE S+ K D P E KV+ I S ++ Q RA RF + T E+KK RA RFG + + N VD+++LKKR ERFG++VS K ++EK KR ERFG+ TS S GG + KK RA RFG Sbjct: 32 ELQKLKLAELRQECDARGLETKGNKGELIARLQ---------AYLEEHE-------------DDVDVDEVLAEDT-------------------------PEFTKVE--SSNSIKEDNHTETIAIPESEDKKVVKISPPLSAGERLQKRAERFNMPA--TAESKKALRAARFGSTTASNPTAGLVVNSKAAVDVDQLKKRAERFGMNVSSISQKIEEDEKLKKRKERFGILTSA---SPGGAEDAEAKKRKRAERFG 234
BLAST of CIP29 vs. Planmine SMEST
Match: SMESG000073815.1 (SMESG000073815.1) HSP 1 Score: 477.633 bits (1228), Expect = 2.997e-172 Identity = 260/261 (99.62%), Postives = 260/261 (99.62%), Query Frame = 2 Query: 50 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTXXXXXXXXXXXXXXILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGGVNLNDDKKAVRAARFGLNTDEEKKKARAARFGN 832 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTSESKEEKNENNLSSILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVG VNLNDDKKAVRAARFGLNTDEEKKKARAARFGN Sbjct: 1 MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAELLGELDGSDSQVVSNVDEDLLLGDSTSESKEEKNENNLSSILQIDEPLSEPPVITDVEEPSAKIPKLDMQPIKETDKVLTIDNSEEKKKQDRAARFGIITNDTEENKKLARAQRFGLDVSKSNGDVTVDIEKLKKREERFGVSVSDKLSKAADEEKKLKRAERFGVQTSIQVESVGSVNLNDDKKAVRAARFGLNTDEEKKKARAARFGN 261 The following BLAST results are available for this feature:
BLAST of CIP29 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 4
BLAST of CIP29 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of CIP29 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of CIP29 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of CIP29 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of CIP29 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 2
BLAST of CIP29 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of CIP29 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of CIP29 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of CIP29 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of CIP29 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of CIP29 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of CIP29 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of CIP29 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30005428 ID=SMED30005428|Name=CIP29|organism=Schmidtea mediterranea sexual|type=transcript|length=903bpback to top protein sequence of SMED30005428-orf-1 >SMED30005428-orf-1 ID=SMED30005428-orf-1|Name=SMED30005428-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=262bp MEDLTKLKVNDLRKKCKDLGLSITGNKSELISRIQDRKNEGGDESVLNEAback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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