Ribonuclease Oy

Overview
NameRibonuclease Oy
Smed IDSMED30005325
Length (bp)840
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ribonuclease Oy (SMED30005325) t-SNE clustered cells

Violin plots show distribution of expression levels for Ribonuclease Oy (SMED30005325) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ribonuclease Oy (SMED30005325) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ribonuclease Oy (SMED30005325) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005325

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Human
Match: RNASET2 (ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686])

HSP 1 Score: 89.3521 bits (220), Expect = 1.998e-20
Identity = 57/187 (30.48%), Postives = 89/187 (47.59%), Query Frame = 2 
Query:  104 RPHTEWDYLVFTQTWASTFCKF--NKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLN-FENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNRN 646
            R + EW  L+  Q W  T C+   N C  P D    WTIHGLWP ++ G     C     FN + I+D+   +   WP++++ F N   FW HEW KHGTC+       ++  YF   L L  ++ + S+     I  S +  Y  +D  +A+  V  V   ++C+   + E    +  +E+CL + 
Sbjct:   29 RDNHEWKKLIMVQHWPETVCEKIQNDCRDPPDY---WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSIN-YYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQIELCLTKQ 206
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Human
Match: RNASET2 (ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686])

HSP 1 Score: 88.9669 bits (219), Expect = 2.333e-20
Identity = 57/187 (30.48%), Postives = 89/187 (47.59%), Query Frame = 2 
Query:  104 RPHTEWDYLVFTQTWASTFCKF--NKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLN-FENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNRN 646
            R + EW  L+  Q W  T C+   N C  P D    WTIHGLWP ++ G     C     FN + I+D+   +   WP++++ F N   FW HEW KHGTC+       ++  YF   L L  ++ + S+     I  S +  Y  +D  +A+  V  V   ++C+   + E    +  +E+CL + 
Sbjct:   29 RDNHEWKKLIMVQHWPETVCEKIQNDCRDPPDY---WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSIN-YYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQIELCLTKQ 206
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Human
Match: RNASET2 (ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686])

HSP 1 Score: 88.9669 bits (219), Expect = 2.333e-20
Identity = 57/187 (30.48%), Postives = 89/187 (47.59%), Query Frame = 2 
Query:  104 RPHTEWDYLVFTQTWASTFCKF--NKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLN-FENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNRN 646
            R + EW  L+  Q W  T C+   N C  P D    WTIHGLWP ++ G     C     FN + I+D+   +   WP++++ F N   FW HEW KHGTC+       ++  YF   L L  ++ + S+     I  S +  Y  +D  +A+  V  V   ++C+   + E    +  +E+CL + 
Sbjct:   29 RDNHEWKKLIMVQHWPETVCEKIQNDCRDPPDY---WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSIN-YYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQIELCLTKQ 206
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Human
Match: AL159163.1 (novel protein)

HSP 1 Score: 80.8777 bits (198), Expect = 5.786e-18
Identity = 44/123 (35.77%), Postives = 61/123 (49.59%), Query Frame = 2 
Query:   98 QARPHTEWDYLVFTQTWASTFCKF--NKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLN-FENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNL 457
            + R + EW  L+  Q W  T C+   N C  P D    WTIHGLWP ++ G     C     FN + I+D+   +   WP++++ F N   FW HEW KHGTC+       ++  YF   L L
Sbjct:    8 RLRDNHEWKKLIMVQHWPETVCEKIQNDCRDPPDY---WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLEL 122
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Human
Match: RNASET2 (ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686])

HSP 1 Score: 80.8777 bits (198), Expect = 1.392e-17
Identity = 53/177 (29.94%), Postives = 83/177 (46.89%), Query Frame = 2 
Query:  134 FTQTWASTFCKF--NKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLN-FENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNRN 646
              Q W  T C+   N C  P D    WTIHGLWP ++ G     C     FN + I+D+   +   WP++++ F N   FW HEW KHGTC+       ++  YF   L L  ++ + S+     I  S +  Y  +D  +A+  V  V   ++C+   + E    +  +E+CL + 
Sbjct:    1 MVQHWPETVCEKIQNDCRDPPDY---WTIHGLWPDKSEG-----CNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSIN-YYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQIELCLTKQ 168
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Celegans
Match: rnst-2 (pep chromosome:WBcel235:V:1061595:1067908:1 gene:WBGene00019624.1 transcript:K10C9.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:rnst-2)

HSP 1 Score: 102.449 bits (254), Expect = 1.565e-25
Identity = 65/211 (30.81%), Postives = 104/211 (49.29%), Query Frame = 2 
Query:   80 IVCVELQARPHTE-WDYLVFTQTWASTFCKFN------KCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQK-FNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKS-TLECV--KIENRWYLSAVEICLNRNLDFIDCPRHKK 679
            I C+ L      E +DYL+FT  + +  C+ +       C  PS     W+IHGLWP+   G++P NC    + F+   I+ I   L V WPNL   +    FW HE+ KHGTC+  + +F +EL+YF   + +        +    + V  +++   +SD+ NA+  V   K+    C+  K   ++ L  + +CLN++L   DCP   K
Sbjct:    9 ISCIPLAYSHDGEPFDYLMFTTIYPTAVCRADDDSVPESCEIPS-GTPQWSIHGLWPNFENGSYPQNCRGTPRHFDENLIKSIEDRLVVVWPNLYPKKTIQSFWKHEYDKHGTCAQSEKLFESELAYFTEVMKV---FDSIDVAGGLKSVGPSEKPITSSDLKNALSGVTSGKTFQFHCLRDKKTKQFLLGDIRLCLNKDLTIRDCPTDGK 215
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Fly
Match: RNaseX25 (gene:FBgn0010406 transcript:FBtr0076752)

HSP 1 Score: 95.1301 bits (235), Expect = 2.372e-22
Identity = 62/200 (31.00%), Postives = 92/200 (46.00%), Query Frame = 2 
Query:   92 ELQARPHTEWDYLVFTQTWASTFCKF-------NKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRW--YLSAVEICLNRNLDFIDC 664
            E+  + H  WD L+FTQ W  T C          +C  P      WTIHG+WP++     P  C     F+   +  I   L   WP+L   ++    W HEW KHGTC++      NEL YF+ GL  + +  +  I  +S I    D +   + + NAI   L    ++ C+        YLS + IC +++L+ IDC
Sbjct:   68 EMSVQDHN-WDVLIFTQQWPVTTCYHWREENPDQECSLPQKK-EFWTIHGIWPTKLHQMGPNFCNNSANFDPSKLNPIEDRLETFWPDLKGMDSTEWLWKHEWQKHGTCAMLVEELDNELKYFEQGLTWREEYIMSRILDASDI--HPDSNNTVAAINNAIVKALGKNPSIHCLYDGKHGISYLSEIRICFSKSLELIDC 263
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Zebrafish
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:791890])

HSP 1 Score: 114.005 bits (284), Expect = 4.492e-30
Identity = 74/208 (35.58%), Postives = 99/208 (47.60%), Query Frame = 2 
Query:   62 FVLILTIV--CVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRW---YLSAVEICLNRNLDFIDCPR 670
            F +I + V  C      P  EW  L+ TQ W  TFCK   C       S WT+HGLWP+  V      C     FNA  IEDI   +   WP+LL   +P  FW +EW+KHGTC+       +E  YF   L L  K  + S+   +QIV S ++ Y   DV  AI S   VK  ++CV          L  +EIC++R+   + C +
Sbjct:    6 FAVIFSAVYLCSSAFTHPRGEWTKLILTQHWPQTFCKMEHC---KTDFSYWTLHGLWPNTGV-----RCNTSWHFNASLIEDILPEMEKFWPDLLEPSSP-KFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPS-EKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK 203
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Zebrafish
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:791890])

HSP 1 Score: 114.005 bits (284), Expect = 4.492e-30
Identity = 74/208 (35.58%), Postives = 99/208 (47.60%), Query Frame = 2 
Query:   62 FVLILTIV--CVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRW---YLSAVEICLNRNLDFIDCPR 670
            F +I + V  C      P  EW  L+ TQ W  TFCK   C       S WT+HGLWP+  V      C     FNA  IEDI   +   WP+LL   +P  FW +EW+KHGTC+       +E  YF   L L  K  + S+   +QIV S ++ Y   DV  AI S   VK  ++CV          L  +EIC++R+   + C +
Sbjct:    6 FAVIFSAVYLCSSAFTHPRGEWTKLILTQHWPQTFCKMEHC---KTDFSYWTLHGLWPNTGV-----RCNTSWHFNASLIEDILPEMEKFWPDLLEPSSP-KFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPS-EKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK 203
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Zebrafish
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:791890])

HSP 1 Score: 114.005 bits (284), Expect = 4.492e-30
Identity = 74/208 (35.58%), Postives = 99/208 (47.60%), Query Frame = 2 
Query:   62 FVLILTIV--CVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRW---YLSAVEICLNRNLDFIDCPR 670
            F +I + V  C      P  EW  L+ TQ W  TFCK   C       S WT+HGLWP+  V      C     FNA  IEDI   +   WP+LL   +P  FW +EW+KHGTC+       +E  YF   L L  K  + S+   +QIV S ++ Y   DV  AI S   VK  ++CV          L  +EIC++R+   + C +
Sbjct:    6 FAVIFSAVYLCSSAFTHPRGEWTKLILTQHWPQTFCKMEHC---KTDFSYWTLHGLWPNTGV-----RCNTSWHFNASLIEDILPEMEKFWPDLLEPSSP-KFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPS-EKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK 203
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Zebrafish
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:791890])

HSP 1 Score: 114.005 bits (284), Expect = 4.492e-30
Identity = 74/208 (35.58%), Postives = 99/208 (47.60%), Query Frame = 2 
Query:   62 FVLILTIV--CVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRW---YLSAVEICLNRNLDFIDCPR 670
            F +I + V  C      P  EW  L+ TQ W  TFCK   C       S WT+HGLWP+  V      C     FNA  IEDI   +   WP+LL   +P  FW +EW+KHGTC+       +E  YF   L L  K  + S+   +QIV S ++ Y   DV  AI S   VK  ++CV          L  +EIC++R+   + C +
Sbjct:    6 FAVIFSAVYLCSSAFTHPRGEWTKLILTQHWPQTFCKMEHC---KTDFSYWTLHGLWPNTGV-----RCNTSWHFNASLIEDILPEMEKFWPDLLEPSSP-KFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPS-EKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK 203
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Zebrafish
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:791890])

HSP 1 Score: 114.005 bits (284), Expect = 4.492e-30
Identity = 74/208 (35.58%), Postives = 99/208 (47.60%), Query Frame = 2 
Query:   62 FVLILTIV--CVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRW---YLSAVEICLNRNLDFIDCPR 670
            F +I + V  C      P  EW  L+ TQ W  TFCK   C       S WT+HGLWP+  V      C     FNA  IEDI   +   WP+LL   +P  FW +EW+KHGTC+       +E  YF   L L  K  + S+   +QIV S ++ Y   DV  AI S   VK  ++CV          L  +EIC++R+   + C +
Sbjct:    6 FAVIFSAVYLCSSAFTHPRGEWTKLILTQHWPQTFCKMEHC---KTDFSYWTLHGLWPNTGV-----RCNTSWHFNASLIEDILPEMEKFWPDLLEPSSP-KFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPS-EKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK 203
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Xenopus
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:780173])

HSP 1 Score: 64.6994 bits (156), Expect = 8.494e-12
Identity = 50/153 (32.68%), Postives = 67/153 (43.79%), Query Frame = 2 
Query:  206 WTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRWYLSAVEICLNRNLDFIDC 664
            WT+HGLWP +       N +P   F    I+DI   L   WP++L+  N    W HEW KHGTC+        +  YF  GL L +K+ + S+   S IV ST                 QV+    C   EN   L  +EIC  + L   +C
Sbjct:   60 WTLHGLWPDK--AQMCNNSWP---FEYSEIQDILPELNHYWPDILH-PNKSQLWKHEWQKHGTCAASLECLNTQHKYFSKGLELYTKVDLNSVLEKSGIVPST--------------KYYQVR----CYLGENVQTLGQIEICFTKELQLRNC 188
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Mouse
Match: Rnaset2a (ribonuclease T2A [Source:MGI Symbol;Acc:MGI:1915445])

HSP 1 Score: 86.6557 bits (213), Expect = 1.384e-19
Identity = 58/189 (30.69%), Postives = 92/189 (48.68%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFCK-FNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFE-NPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNR-NLDFIDC 664
            EW  L+ TQ W  T CK  N C    D++  WTIHGLWP R       +C     FN   I+D+   + + WP++++   N   FW HEW KHGTC+       +E  YF   L+L  +I + S+     I  S +  Y  +D  +A+  +  V   ++C+   + E+   +  +E+C  + +L   +C
Sbjct:   38 EWKKLILTQHWPPTVCKEVNSCQ---DSLDYWTIHGLWPDRAE-----DCNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNC 217
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Mouse
Match: Rnaset2a (ribonuclease T2A [Source:MGI Symbol;Acc:MGI:1915445])

HSP 1 Score: 86.6557 bits (213), Expect = 1.384e-19
Identity = 58/189 (30.69%), Postives = 92/189 (48.68%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFCK-FNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFE-NPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNR-NLDFIDC 664
            EW  L+ TQ W  T CK  N C    D++  WTIHGLWP R       +C     FN   I+D+   + + WP++++   N   FW HEW KHGTC+       +E  YF   L+L  +I + S+     I  S +  Y  +D  +A+  +  V   ++C+   + E+   +  +E+C  + +L   +C
Sbjct:   38 EWKKLILTQHWPPTVCKEVNSCQ---DSLDYWTIHGLWPDRAE-----DCNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNC 217
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Mouse
Match: Gm49673 (predicted gene, 49673 [Source:MGI Symbol;Acc:MGI:6215117])

HSP 1 Score: 86.6557 bits (213), Expect = 1.384e-19
Identity = 58/189 (30.69%), Postives = 92/189 (48.68%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFCK-FNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFE-NPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNR-NLDFIDC 664
            EW  L+ TQ W  T CK  N C    D++  WTIHGLWP R       +C     FN   I+D+   + + WP++++   N   FW HEW KHGTC+       +E  YF   L+L  +I + S+     I  S +  Y  +D  +A+  +  V   ++C+   + E+   +  +E+C  + +L   +C
Sbjct:   38 EWKKLILTQHWPPTVCKEVNSCQ---DSLDYWTIHGLWPDRAE-----DCNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNC 217
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Mouse
Match: Gm49721 (predicted gene, 49721 [Source:MGI Symbol;Acc:MGI:6215195])

HSP 1 Score: 86.6557 bits (213), Expect = 1.384e-19
Identity = 58/189 (30.69%), Postives = 92/189 (48.68%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFCK-FNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFE-NPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNR-NLDFIDC 664
            EW  L+ TQ W  T CK  N C    D++  WTIHGLWP R       +C     FN   I+D+   + + WP++++   N   FW HEW KHGTC+       +E  YF   L+L  +I + S+     I  S +  Y  +D  +A+  +  V   ++C+   + E+   +  +E+C  + +L   +C
Sbjct:   38 EWKKLILTQHWPPTVCKEVNSCQ---DSLDYWTIHGLWPDRAE-----DCNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNC 217
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Mouse
Match: Rnaset2b (ribonuclease T2B [Source:MGI Symbol;Acc:MGI:3702087])

HSP 1 Score: 86.6557 bits (213), Expect = 1.384e-19
Identity = 58/189 (30.69%), Postives = 92/189 (48.68%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFCK-FNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFE-NPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNR-NLDFIDC 664
            EW  L+ TQ W  T CK  N C    D++  WTIHGLWP R       +C     FN   I+D+   + + WP++++   N   FW HEW KHGTC+       +E  YF   L+L  +I + S+     I  S +  Y  +D  +A+  +  V   ++C+   + E+   +  +E+C  + +L   +C
Sbjct:   38 EWKKLILTQHWPPTVCKEVNSCQ---DSLDYWTIHGLWPDRAE-----DCNQSWHFNLDEIKDLLRDMKIYWPDVIHRSSNRSQFWKHEWVKHGTCAAQVDALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSIN-YYQLADFKDALTRIYGVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNC 217
[Close]
BLAST of Ribonuclease Oy vs. UniProt/SwissProt
Match: sp|B8XY56|RNT2_DANRE (Ribonuclease T2 OS=Danio rerio OX=7955 GN=rnaset2 PE=2 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 3.391e-29
Identity = 74/208 (35.58%), Postives = 99/208 (47.60%), Query Frame = 2 
Query:   62 FVLILTIV--CVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRW---YLSAVEICLNRNLDFIDCPR 670
            F +I + V  C      P  EW  L+ TQ W  TFCK   C       S WT+HGLWP+  V      C     FNA  IEDI   +   WP+LL   +P  FW +EW+KHGTC+       +E  YF   L L  K  + S+   +QIV S ++ Y   DV  AI S   VK  ++CV          L  +EIC++R+   + C +
Sbjct:    6 FAVIFSAVYLCSSAFTHPRGEWTKLILTQHWPQTFCKMEHC---KTDFSYWTLHGLWPNTGV-----RCNTSWHFNASLIEDILPEMEKFWPDLLEPSSP-KFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPS-EKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEK 203
[Close]
BLAST of Ribonuclease Oy vs. UniProt/SwissProt
Match: sp|Q7M456|RNOY_CRAGI (Ribonuclease Oy OS=Crassostrea gigas OX=29159 PE=1 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 3.929e-29
Identity = 66/187 (35.29%), Postives = 90/187 (48.13%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSR-TVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNRNLDFIDC 664
            +W+Y  F Q W    C  +K  F  D++  W IHGLWPS  T    P NC     F+  N+  +   L   WPNL        FW HEWSKHGTC+   P  +NEL YF  GL L +K  I  I  +  I+ S    Y  ++   A++  L V + +ECV   +   +  L  + ICL +  + I C
Sbjct:    2 DWNYFTFAQQWPIAVCAEHKSCFIPDSVVGWGIHGLWPSSDTESKGPENCNGSWPFDINNVMPLVPELKKYWPNLYPDTKANSFWEHEWSKHGTCATSLPATSNELKYFGMGLKLHAKYNISRILVNQGILPSKTAGYMINETEAAVKRELGVDAVIECVYDKEKTKKQLLYEISICLTKEFELISC 188
[Close]
BLAST of Ribonuclease Oy vs. UniProt/SwissProt
Match: sp|Q7M438|RNDI_DICDI (Ribonuclease DdI OS=Dictyostelium discoideum OX=44689 GN=ddiA PE=1 SV=3)

HSP 1 Score: 107.457 bits (267), Expect = 7.556e-27
Identity = 67/198 (33.84%), Postives = 104/198 (52.53%), Query Frame = 2 
Query:   77 TIVCVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRWYLSAVEICLNRN-LDFIDCP 667
            + V +   ++P  ++D+ +F Q W  ++C    C   +     +TIHGLWP  + G++P  C  G  FN   I+D+   L  +WP+L        FWTHE+SKHGTCS+  PI T+   YF TG+ L ++  I +   S  I  S   +Y   D+ NAI +    K  ++C   +    LS V +C+++N L  +DCP
Sbjct:   19 STVTIYESSKPG-DFDFYLFVQQWIYSYCDSQTC-IQNKEREAFTIHGLWPENSDGSYPSFC-SGPSFNVNAIQDLEDQLNFDWPSLTGPNTD--FWTHEFSKHGTCSITGPI-TDIHDYFATGIKLYTEFNITAALESENIYPSDSNTYKPVDITNAITTHFGGKPGIQCSSGQ----LSTVAVCIDKNSLSIMDCP 206
[Close]
BLAST of Ribonuclease Oy vs. UniProt/SwissProt
Match: sp|O80324|RNS6_PYRPY (Ribonuclease S-6 OS=Pyrus pyrifolia OX=3767 PE=1 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 4.143e-25
Identity = 65/208 (31.25%), Postives = 101/208 (48.56%), Query Frame = 2 
Query:   62 FVLILTIVCVELQARPHTEWDYLVFTQTWASTFCKFNK--CHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQI-VQSTDESYNTSDVVNAIQ-SVLQVKSTLECVKIENRWYLSAVEICLNRNL-DFIDCPR 670
            F LI+ I C          ++Y  FTQ +    C  N   C  P D +  +T+HGLWPS  VG  P+ C   +   +Q I ++ + L + WPN+L+  + + FW  +W+KHG+C    P   +E+ YF+T + +            S+  ++   +     D++NAI+      K  L+C K      L  + IC +RNL  FIDCPR
Sbjct:   14 FSLIVLISCSSTMG-----YNYFQFTQQYQPAVCNSNPTPCKDPPDKL--FTVHGLWPSNDVGDDPIYCK-NKTIKSQQIGNLTAQLIIIWPNVLDRTDHVGFWNRQWNKHGSCG-KAPTIKDEMHYFKTVIKMYITQKQNVSEILSRAKIEPEGKIRRRDDIINAIRLGTKDKKPKLKCQKNNQTTELVEITICSDRNLTQFIDCPR 212
[Close]
BLAST of Ribonuclease Oy vs. UniProt/SwissProt
Match: sp|O61887|RNST2_CAEEL (Ribonuclease T2 protein rnst-2 OS=Caenorhabditis elegans OX=6239 GN=rnst-2 PE=1 SV=2)

HSP 1 Score: 102.449 bits (254), Expect = 1.990e-24
Identity = 65/211 (30.81%), Postives = 104/211 (49.29%), Query Frame = 2 
Query:   80 IVCVELQARPHTE-WDYLVFTQTWASTFCKFN------KCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQK-FNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKS-TLECV--KIENRWYLSAVEICLNRNLDFIDCPRHKK 679
            I C+ L      E +DYL+FT  + +  C+ +       C  PS     W+IHGLWP+   G++P NC    + F+   I+ I   L V WPNL   +    FW HE+ KHGTC+  + +F +EL+YF   + +        +    + V  +++   +SD+ NA+  V   K+    C+  K   ++ L  + +CLN++L   DCP   K
Sbjct:    9 ISCIPLAYSHDGEPFDYLMFTTIYPTAVCRADDDSVPESCEIPS-GTPQWSIHGLWPNFENGSYPQNCRGTPRHFDENLIKSIEDRLVVVWPNLYPKKTIQSFWKHEYDKHGTCAQSEKLFESELAYFTEVMKV---FDSIDVAGGLKSVGPSEKPITSSDLKNALSGVTSGKTFQFHCLRDKKTKQFLLGDIRLCLNKDLTIRDCPTDGK 215
[Close]
BLAST of Ribonuclease Oy vs. TrEMBL
Match: A0A4Z2DFD4 (Ribonuclease Oy OS=Schistosoma japonicum OX=6182 GN=EWB00_001525 PE=3 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 4.982e-36
Identity = 72/207 (34.78%), Postives = 109/207 (52.66%), Query Frame = 2 
Query:   53 IRKFVLILTIVCVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENR---WYLSAVEICLNRNLDFIDC 664
            I   +LIL ++     ++   +W+Y VFT TW  TFC + KC  P   ++ +TIHGLWPS   G  P NC    +F+   ++ I + L   W NLLN+ENP PFW HEW KHG C +++ + +NEL+YF T + LK K+ + +   S  I  +       S  +N ++    V + ++C     +     L+ +  C N  L  IDC
Sbjct:    6 INSLILILFMIVHMSDSQKDGDWNYFVFTLTWPPTFCSYKKCKLPP-GLNDFTIHGLWPSIWPGKQPTNCSAHSRFDIHRLQSIRNKLDYTWANLLNYENPSPFWEHEWYKHGQCGIENVLISNELNYFNTAVELKEKLNLLTQLKSYGIQPNNSVVIEKSHFLNVLKQAYNVSAVVKCKSKRRKDKLTKLAEIRFCFNVKLQLIDC 211
[Close]
BLAST of Ribonuclease Oy vs. TrEMBL
Match: Q5DC79 (SJCHGC05678 protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 6.302e-36
Identity = 72/207 (34.78%), Postives = 108/207 (52.17%), Query Frame = 2 
Query:   53 IRKFVLILTIVCVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENR---WYLSAVEICLNRNLDFIDC 664
            I   +LIL ++     ++   +W+Y VFT TW  TFC + KC  P   ++ +TIHGLWPS   G  P NC    +F+   ++ I + L   W NLLN+ENP PFW HEW KHG C +++ +  NEL+YF T + LK K+ + +   S  I  +       S  +N ++    V + ++C     +     L+ +  C N  L  IDC
Sbjct:    6 INSLILILFMIVHMSDSQKGGDWNYFVFTLTWPPTFCSYKKCKLPP-GLNDFTIHGLWPSIWPGKQPTNCSAHSRFDIHRLQSIRNKLDYTWANLLNYENPTPFWEHEWYKHGQCGIENVLIRNELNYFNTAVELKEKLNLLTQLKSYGIQPNNSVVIEKSHFLNVLKQAYNVSAVVKCKSKRRKDKLTKLAEIRFCFNVKLQLIDC 211
[Close]
BLAST of Ribonuclease Oy vs. TrEMBL
Match: A0A4Z2DFD7 (Ribonuclease Oy isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_001528 PE=3 SV=1)

HSP 1 Score: 132.494 bits (332), Expect = 2.417e-33
Identity = 77/206 (37.38%), Postives = 113/206 (54.85%), Query Frame = 2 
Query:   53 IRKFVLILTIVCVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENR-WYLSAVEICLNRNLDFIDCP 667
            + +FVL  T VC E Q      WDYLV++  W  T+C  + C  P + I+ + IHGLWPS      P NC     F    I+ IY+ L  EW NL +F++P  FW HEW KHG C+L DPI +NEL YF   L +KSK+ +     S +I+ S   +     ++N ++ +  V   + C  I ++   L+ + +CLN +++FI CP
Sbjct:    9 VARFVLC-THVCGERQ------WDYLVYSLEWPPTYCFTHTCKLPYN-INNFNIHGLWPSIWPSGSPTNCPNHMPFEIDTIKPIYTELQKEWANLDDFDDPKAFWKHEWQKHGVCALSDPIISNELDYFNISLIMKSKVNLLRRLESIKIIPSDSVTLKRDVLLNQLKKLFNVDVLMYCFLIHHKPAKLAEIRLCLNPSMEFISCP 206
[Close]
BLAST of Ribonuclease Oy vs. TrEMBL
Match: A0A4Z2DG04 (Ribonuclease Oy isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_001528 PE=3 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 5.907e-33
Identity = 77/206 (37.38%), Postives = 113/206 (54.85%), Query Frame = 2 
Query:   53 IRKFVLILTIVCVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENR-WYLSAVEICLNRNLDFIDCP 667
            + +FVL  T VC E Q      WDYLV++  W  T+C  + C  P + I+ + IHGLWPS      P NC     F    I+ IY+ L  EW NL +F++P  FW HEW KHG C+L DPI +NEL YF   L +KSK+ +     S +I+ S   +     ++N ++ +  V   + C  I ++   L+ + +CLN +++FI CP
Sbjct:   29 VARFVLC-THVCGERQ------WDYLVYSLEWPPTYCFTHTCKLPYN-INNFNIHGLWPSIWPSGSPTNCPNHMPFEIDTIKPIYTELQKEWANLDDFDDPKAFWKHEWQKHGVCALSDPIISNELDYFNISLIMKSKVNLLRRLESIKIIPSDSVTLKRDVLLNQLKKLFNVDVLMYCFLIHHKPAKLAEIRLCLNPSMEFISCP 226
[Close]
BLAST of Ribonuclease Oy vs. TrEMBL
Match: T2MJ99 (Ribonuclease T2 OS=Hydra vulgaris OX=6087 GN=RNASET2 PE=2 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 5.635e-32
Identity = 76/191 (39.79%), Postives = 103/191 (53.93%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFCKF-------NKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIEN-RWYLSAVEICLNRNLDFIDC 664
            EWDY +    W  + C++       + C  P DA++ WTIHGLWPS   G  P  C P  KF+   ++D+   L + WPN+     P  FW HE+ KHGTC+     F  E  YFQ  L L+ K  I  + S S+IV STD SY  SD+  A++S    K   EC  I++ +  LSA  +CLN+ L+ IDC
Sbjct:   42 EWDYFMLVTEWPQSSCEYVNATHQHHTCVIP-DAVNGWTIHGLWPSVEKGEQPFFCEPW-KFDEDKVKDLEGNLELYWPNIFVETTPQSFWKHEYEKHGTCASSVKGFETEHDYFQKALELREKFDIMRVLSESKIVPSTDSSYQFSDIEEALKSGYSAKVCFECSGIKHSQQVLSAGYVCLNKQLEQIDC 230
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Cavefish
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:103036121])

HSP 1 Score: 98.9821 bits (245), Expect = 2.578e-24
Identity = 63/188 (33.51%), Postives = 92/188 (48.94%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRWYLSAV---EICLNRNLDFIDCPR 670
            +W  L+ T  W  TFC  ++C   +   S WT+HG WP+  VG     C     FNA  IED+   +   WP+LL   +   FW HEW KHGTC+  D    ++  YF   L L  K+ +  +   SQIV S ++ Y  +D+  +I S   V   ++CV    R  +  V   EIC+++     DC +
Sbjct:   25 DWTKLILTHHWPKTFCMIDQC---TTNFSYWTLHGFWPN--VGNM---CNSSWHFNASLIEDLLPEMKTYWPDLLKPAS-TQFWKHEWEKHGTCAAKDEDLDSQHKYFSKALELYHKLDLDGVLKKSQIVPS-EKYYKLADLEESIVSSFGVTPKIQCVLEAKRAEVQTVGQIEICVDKQFQLTDCEK 202
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Cavefish
Match: rnaset2l (ribonuclease Oy-like [Source:NCBI gene;Acc:103022964])

HSP 1 Score: 80.8777 bits (198), Expect = 1.429e-17
Identity = 54/167 (32.34%), Postives = 83/167 (49.70%), Query Frame = 2 
Query:  119 WDYLVFTQTWASTFC----KFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENR 607
            W  ++FT  W  +FC      N C  P + I  WTIHGLWP RT G     C+P  + + Q++E   S L   WP+L+  ++   FW  EW KHGTC+       +   YF+T L L++   + +  +++ I  S + SY   ++  A+   L     ++CVK E  
Sbjct:   44 WTCMIFTIQWPGSFCLSLENRNICRIPEN-IHNWTIHGLWPIRTYGC--CFCWPVFQSHLQDLEPELSQL---WPSLIKSKSNFSFWKDEWFKHGTCAACVESMGSPAHYFRTSLKLRTLFDVDNALANTGIKPSCNISYKHEEIHAALGPFLGNNYVVQCVKDEKE 204
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Sea Lamprey
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:791890])

HSP 1 Score: 99.7525 bits (247), Expect = 2.533e-25
Identity = 62/217 (28.57%), Postives = 102/217 (47.00%), Query Frame = 2 
Query:   65 VLILTIVCVELQARPHTEWDYLVFTQTWASTFC-----KFNKCHFPSDAISPWTIHGLWPS-RTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKI---ENRWYLSAVEICLNRNLDFIDCPRHKKKSI 688
            + ++  V V   AR + +W  L+ TQ W  +FC     + + C  PS ++  W+IHGLW + RT       C     F+ + IED+   L   WP+L    N    W HEW +HGTC+       ++ +YF   + L  K+ I    S + +  S    Y    ++ A  +   VK+ L+C+ +   EN   L  +++C +R    ++C RH +  I
Sbjct:   11 IFVIAAVSVPSYARRYEDWSQLILTQHWPQSFCMSQWSEKHNCTIPS-SVKSWSIHGLWTNHRTF------CNKSWHFDVKEIEDLLPQLDQFWPDLEK-TNGTDLWKHEWIRHGTCAATLEALNSQHNYFSKTMELYQKLDISKALSDAGVTPSNTVFYKEEQILEAFSTAFGVKAKLQCLTVPQEENTQLLGQIQMCWSREFSLVNCSRHAEAGI 219
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Nematostella
Match: EDO48543 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ98])

HSP 1 Score: 95.9005 bits (237), Expect = 1.414e-23
Identity = 65/229 (28.38%), Postives = 105/229 (45.85%), Query Frame = 2 
Query:   53 IRKFVLILTIVCVELQARPHT----EWDYLVFTQTWASTFCKF------------------NKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIP--FWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKI-ENRWYLSAVEICLNRNLDFIDC 664
            +R   +I T+V +   ++  +    +WDY VF+Q W  + C +                  N C  P+D ++ WT+HGLWP+    A PVNC     F    I+D+   +   W    +         W+HEW KHGTC+ D    +NE SYF   L L S   +    +S  I+ S D+ Y    V  AI +    K  + C++  +++  L+ + ICL+++    +C
Sbjct:    1 MRTGCVIATLVIILTASQAFSLESHKWDYFVFSQWWPQSQCYYRNGQTMDDKWRFTSGNARNDC-VPAD-VTTWTLHGLWPTVGGKAEPVNCNSSWPFVESEIQDLEDRMMQRWLAFPDSSKSSARDLWSHEWKKHGTCATDLAQTSNEHSYFSMALALNSNCGLLRALASENIIPSDDQMYTVKQVERAISNKYGAKGRVICLRGPDDQQLLAGIRICLDKSFRPRNC 227
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Nematostella
Match: EDO48544 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ99])

HSP 1 Score: 87.8113 bits (216), Expect = 1.276e-20
Identity = 57/184 (30.98%), Postives = 81/184 (44.02%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFCKF------------------NKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIP--FWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENR 607
            +WDY VF+Q W  + C +                  N C  P+D ++ WT+HGLWP+    A PVNC     F    I+D+   +   W    +         W+HEW KHGTC+ D    +NE SYF   L L S   +    +S  I+ S D+ Y    V  AI +    K  + C++   R
Sbjct:   19 KWDYFVFSQWWPQSQCYYRNGQTMDDKWRFTSGNARNDC-VPAD-VTTWTLHGLWPTVGGKAEPVNCNSSWPFVESEIQDLEDRMMQRWLAFPDSSKSSARDLWSHEWKKHGTCATDLAETSNEHSYFSMALALNSNCGLLRALASENIIPSDDQMYTVKQVERAISNKYGAKGRVICLRGPAR 200
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Medaka
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:101163650])

HSP 1 Score: 108.612 bits (270), Expect = 4.477e-28
Identity = 69/210 (32.86%), Postives = 99/210 (47.14%), Query Frame = 2 
Query:   68 LILTIVCVELQA--RPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNRNLDFIDCPRHKKK 682
            L+    CV   A   PH  W  L+ T  W +TFC    CH     IS WT+HGLWP + +     +C     FN   IED+   +   WP+L N  + + FW +EW KHGTC+       ++  YF   L L  K+ + S+     I  S D+ Y  S V  AI++V   K  ++CV   K  +   L  +EIC + +   +DC +   K
Sbjct:    8 LLALCACVSWAAVISPHHMWSKLILTHHWPNTFCSMEHCH---PNISYWTLHGLWPDKGM-----DCNSSWHFNPSLIEDLLPDMNKSWPDLRN-RSSVSFWKYEWHKHGTCAAKAESLNSQHKYFSKALELYHKLDLSSVLVKFGITPS-DKYYPFSQVEGAIENVYGFKPKIQCVHSSKGGDFQSLGQIEICFDSDFTLMDCEKQSAK 207
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Medaka
Match: rnaset2 (ribonuclease T2 [Source:NCBI gene;Acc:101163650])

HSP 1 Score: 108.612 bits (270), Expect = 4.477e-28
Identity = 69/210 (32.86%), Postives = 99/210 (47.14%), Query Frame = 2 
Query:   68 LILTIVCVELQA--RPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNRNLDFIDCPRHKKK 682
            L+    CV   A   PH  W  L+ T  W +TFC    CH     IS WT+HGLWP + +     +C     FN   IED+   +   WP+L N  + + FW +EW KHGTC+       ++  YF   L L  K+ + S+     I  S D+ Y  S V  AI++V   K  ++CV   K  +   L  +EIC + +   +DC +   K
Sbjct:    8 LLALCACVSWAAVISPHHMWSKLILTHHWPNTFCSMEHCH---PNISYWTLHGLWPDKGM-----DCNSSWHFNPSLIEDLLPDMNKSWPDLRN-RSSVSFWKYEWHKHGTCAAKAESLNSQHKYFSKALELYHKLDLSSVLVKFGITPS-DKYYPFSQVEGAIENVYGFKPKIQCVHSSKGGDFQSLGQIEICFDSDFTLMDCEKQSAK 207
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Medaka
Match: rnaset2l (ribonuclease Oy [Source:NCBI gene;Acc:101170531])

HSP 1 Score: 83.1889 bits (204), Expect = 1.944e-18
Identity = 67/223 (30.04%), Postives = 106/223 (47.53%), Query Frame = 2 
Query:   62 FVLILTIVCVELQ--AR-------PHTE-----WDYLVFTQTWASTFCK--FNK--CHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNRNLDFIDCP 667
             V++L +V +E Q  AR       P T      W  ++FT  W   FC   +N+  C  P D ++ WTIHGLWP         NC+P  + + Q ++D    L   WP+LL  ++   FW  EW+KHG C+     F +   YFQ  L L+    I+ +   + I  S +  Y  ++V + +   +  +  ++CV   K    W+   V+I L+R+L  + CP
Sbjct:   16 LVILLPLVAMETQEEARGCRGASPPQTSEHDCAWRCIIFTLQWPGGFCASLYNQTLCRIP-DTVTDWTIHGLWPLHAQRC--CNCWPMFQSDVQELKD---ELVENWPSLLKTKSSFQFWEQEWAKHGACAACVEGFNSPQKYFQISLKLRKWFEIQRVLEDAGIAPSCERRYKVAEVQSILTPHVGDQYEIQCVLDHKDRQVWF--QVKIRLSRDLT-LGCP 229
[Close]
BLAST of Ribonuclease Oy vs. Ensembl Medaka
Match: rnaset2l (ribonuclease Oy [Source:NCBI gene;Acc:101170531])

HSP 1 Score: 83.1889 bits (204), Expect = 1.944e-18
Identity = 67/223 (30.04%), Postives = 106/223 (47.53%), Query Frame = 2 
Query:   62 FVLILTIVCVELQ--AR-------PHTE-----WDYLVFTQTWASTFCK--FNK--CHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV---KIENRWYLSAVEICLNRNLDFIDCP 667
             V++L +V +E Q  AR       P T      W  ++FT  W   FC   +N+  C  P D ++ WTIHGLWP         NC+P  + + Q ++D    L   WP+LL  ++   FW  EW+KHG C+     F +   YFQ  L L+    I+ +   + I  S +  Y  ++V + +   +  +  ++CV   K    W+   V+I L+R+L  + CP
Sbjct:   16 LVILLPLVAMETQEEARGCRGASPPQTSEHDCAWRCIIFTLQWPGGFCASLYNQTLCRIP-DTVTDWTIHGLWPLHAQRC--CNCWPMFQSDVQELKD---ELVENWPSLLKTKSSFQFWEQEWAKHGACAACVEGFNSPQKYFQISLKLRKWFEIQRVLEDAGIAPSCERRYKVAEVQSILTPHVGDQYEIQCVLDHKDRQVWF--QVKIRLSRDLT-LGCP 229
[Close]
BLAST of Ribonuclease Oy vs. Planmine SMEST
Match: SMESG000016389.1 (SMESG000016389.1)

HSP 1 Score: 154.066 bits (388), Expect = 2.073e-46
Identity = 82/183 (44.81%), Postives = 111/183 (60.66%), Query Frame = 2 
Query:   53 IRKFVLILTIVCVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIE 601
            + K ++IL++V V L A     WDYL +T  W  TFCK+N+C++    ++ W IHGLWPS   G  P  C  G  FN  ++  I+  L V+W NLL F NP  FWTHEW+KHG C++  P+FTNELSYF   L LK  +++  I S + I  S D+ Y+T  V  ++ S L V   LEC+KIE
Sbjct:    1 MLKLLIILSVVGVSLSAN----WDYLTYTLLWPQTFCKYNQCNYDKTKVTGWNIHGLWPSNITGKDPSKC-KGDPFNINDLNSIFPDLVVQWANLLEFTNPAEFWTHEWTKHGLCAILPPLFTNELSYFSRSLQLKQFVSLDKILSDNDIQPSDDKQYDTDSVSKSVSSKLGVLPKLECIKIE 178
[Close]
BLAST of Ribonuclease Oy vs. Planmine SMEST
Match: SMESG000046228.1 (SMESG000046228.1)

HSP 1 Score: 115.546 bits (288), Expect = 4.823e-31
Identity = 64/157 (40.76%), Postives = 91/157 (57.96%), Query Frame = 2 
Query:  200 SPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIE-DIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECV-KIENRWYLSAVEICLNRNLDFIDC 664
            S W IHGLWP +  G    NC  G+ F  Q +   IY  L + W NL NF  P  FW +EW KHGTCS+ D +F+NE  YF   L LK  I++K + S+  I+ + D++YN   + NAI+  L +   L+C  K +N W L ++ IC +R+++  DC
Sbjct:   18 SRWNIHGLWPYKIHGNDTFNC-DGEPFQRQLVLISIYEELLLNWANLKNFSKPEKFWGYEWHKHGTCSIKDKLFSNEFGYFYHTLRLKKNISMKKLLSNHNILPNNDKAYNIQQIHNAIKVELGIIPMLQCFQKQDNEWNLLSIGICFDRSMNLKDC 173
[Close]
BLAST of Ribonuclease Oy vs. Planmine SMEST
Match: SMESG000048912.1 (SMESG000048912.1)

HSP 1 Score: 114.005 bits (284), Expect = 3.636e-30
Identity = 66/214 (30.84%), Postives = 106/214 (49.53%), Query Frame = 2 
Query:   53 IRKFVLILTIVCVELQARPHTEWDYLVFTQTWASTFC-----KFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRWYLSAVEICLNRNLDFIDCP-RHK 676
            I+ F+LI+  +          +WDYLV    W  +FC     K   C   +  ++ W +HGLWPS + G+ P+ C     ++ + ++ I   L  EW  L N      FW HEW  HGTC+  + +   EL YF   + +K  + + +I   + +    ++ Y  SD VN I+ V +V+  L+C   + + Y+ A+E C +  L+ I CP RHK
Sbjct:    4 IKYFLLIILSIYTSSIWMKDEDWDYLVMAVEWPPSFCYTFPKKIQCCD--TSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD--FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHK 213
[Close]
BLAST of Ribonuclease Oy vs. Planmine SMEST
Match: SMESG000048912.1 (SMESG000048912.1)

HSP 1 Score: 111.694 bits (278), Expect = 1.952e-29
Identity = 62/193 (32.12%), Postives = 98/193 (50.78%), Query Frame = 2 
Query:  116 EWDYLVFTQTWASTFC-----KFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRWYLSAVEICLNRNLDFIDCP-RHK 676
            +WDYLV    W  +FC     K   C   +  ++ W +HGLWPS + G+ P+ C     ++ + ++ I   L  EW  L N      FW HEW  HGTC+  + +   EL YF   + +K  + + +I   + +    ++ Y  SD VN I+ V +V+  L+C   + + Y+ A+E C +  L+ I CP RHK
Sbjct:    5 DWDYLVMAVEWPPSFCYTFPKKIQCCD--TSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD--FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHK 193
[Close]
BLAST of Ribonuclease Oy vs. Planmine SMEST
Match: SMESG000048912.1 (SMESG000048912.1)

HSP 1 Score: 100.138 bits (248), Expect = 3.567e-25
Identity = 57/183 (31.15%), Postives = 92/183 (50.27%), Query Frame = 2 
Query:  146 WASTFC-----KFNKCHFPSDAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLLNFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLXXXXXXXXXXXXXQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRWYLSAVEICLNRNLDFIDCP-RHK 676
            W  +FC     K   C   +  ++ W +HGLWPS + G+ P+ C     ++ + ++ I   L  EW  L N      FW HEW  HGTC+  + +   EL YF   + +K  + + +I   + +    ++ Y  SD VN I+ V +V+  L+C   + + Y+ A+E C +  L+ I CP RHK
Sbjct:    5 WPPSFCYTFPKKIQCCD--TSHVTGWNLHGLWPSSSKGSDPLCCKNASAYDEKKLKPIMEDLLKEWNPLGNCSKD--FWKHEWKFHGTCASHNKLLHTELQYFNETIQMKKHVDLTNILHQNNVKPDNNKMYKVSDFVNVIKKVYKVEPKLQCTHYKGKIYILAMEFCFDTKLNIIMCPKRHK 183
The following BLAST results are available for this feature:
BLAST of Ribonuclease Oy vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RNASET21.998e-2030.48ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686... [more]
RNASET22.333e-2030.48ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686... [more]
RNASET22.333e-2030.48ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686... [more]
AL159163.15.786e-1835.77novel protein[more]
RNASET21.392e-1729.94ribonuclease T2 [Source:HGNC Symbol;Acc:HGNC:21686... [more]
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BLAST of Ribonuclease Oy vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnst-21.565e-2530.81pep chromosome:WBcel235:V:1061595:1067908:1 gene:W... [more]
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BLAST of Ribonuclease Oy vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
RNaseX252.372e-2231.00gene:FBgn0010406 transcript:FBtr0076752[more]
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BLAST of Ribonuclease Oy vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnaset24.492e-3035.58ribonuclease T2 [Source:NCBI gene;Acc:791890][more]
rnaset24.492e-3035.58ribonuclease T2 [Source:NCBI gene;Acc:791890][more]
rnaset24.492e-3035.58ribonuclease T2 [Source:NCBI gene;Acc:791890][more]
rnaset24.492e-3035.58ribonuclease T2 [Source:NCBI gene;Acc:791890][more]
rnaset24.492e-3035.58ribonuclease T2 [Source:NCBI gene;Acc:791890][more]
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BLAST of Ribonuclease Oy vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnaset28.494e-1232.68ribonuclease T2 [Source:NCBI gene;Acc:780173][more]
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BLAST of Ribonuclease Oy vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rnaset2a1.384e-1930.69ribonuclease T2A [Source:MGI Symbol;Acc:MGI:191544... [more]
Rnaset2a1.384e-1930.69ribonuclease T2A [Source:MGI Symbol;Acc:MGI:191544... [more]
Gm496731.384e-1930.69predicted gene, 49673 [Source:MGI Symbol;Acc:MGI:6... [more]
Gm497211.384e-1930.69predicted gene, 49721 [Source:MGI Symbol;Acc:MGI:6... [more]
Rnaset2b1.384e-1930.69ribonuclease T2B [Source:MGI Symbol;Acc:MGI:370208... [more]
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BLAST of Ribonuclease Oy vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|B8XY56|RNT2_DANRE3.391e-2935.58Ribonuclease T2 OS=Danio rerio OX=7955 GN=rnaset2 ... [more]
sp|Q7M456|RNOY_CRAGI3.929e-2935.29Ribonuclease Oy OS=Crassostrea gigas OX=29159 PE=1... [more]
sp|Q7M438|RNDI_DICDI7.556e-2733.84Ribonuclease DdI OS=Dictyostelium discoideum OX=44... [more]
sp|O80324|RNS6_PYRPY4.143e-2531.25Ribonuclease S-6 OS=Pyrus pyrifolia OX=3767 PE=1 S... [more]
sp|O61887|RNST2_CAEEL1.990e-2430.81Ribonuclease T2 protein rnst-2 OS=Caenorhabditis e... [more]
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BLAST of Ribonuclease Oy vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Z2DFD44.982e-3634.78Ribonuclease Oy OS=Schistosoma japonicum OX=6182 G... [more]
Q5DC796.302e-3634.78SJCHGC05678 protein OS=Schistosoma japonicum OX=61... [more]
A0A4Z2DFD72.417e-3337.38Ribonuclease Oy isoform 2 OS=Schistosoma japonicum... [more]
A0A4Z2DG045.907e-3337.38Ribonuclease Oy isoform 1 OS=Schistosoma japonicum... [more]
T2MJ995.635e-3239.79Ribonuclease T2 OS=Hydra vulgaris OX=6087 GN=RNASE... [more]
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BLAST of Ribonuclease Oy vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rnaset22.578e-2433.51ribonuclease T2 [Source:NCBI gene;Acc:103036121][more]
rnaset2l1.429e-1732.34ribonuclease Oy-like [Source:NCBI gene;Acc:1030229... [more]
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BLAST of Ribonuclease Oy vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnaset22.533e-2528.57ribonuclease T2 [Source:NCBI gene;Acc:791890][more]
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BLAST of Ribonuclease Oy vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ribonuclease Oy vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO485431.414e-2328.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO485441.276e-2030.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ribonuclease Oy vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
rnaset24.477e-2832.86ribonuclease T2 [Source:NCBI gene;Acc:101163650][more]
rnaset24.477e-2832.86ribonuclease T2 [Source:NCBI gene;Acc:101163650][more]
rnaset2l1.944e-1830.04ribonuclease Oy [Source:NCBI gene;Acc:101170531][more]
rnaset2l1.944e-1830.04ribonuclease Oy [Source:NCBI gene;Acc:101170531][more]
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BLAST of Ribonuclease Oy vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000016389.12.073e-4644.81SMESG000016389.1[more]
SMESG000046228.14.823e-3140.76SMESG000046228.1[more]
SMESG000048912.13.636e-3030.84SMESG000048912.1[more]
SMESG000048912.11.952e-2932.12SMESG000048912.1[more]
SMESG000048912.13.567e-2531.15SMESG000048912.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005325 ID=SMED30005325|Name=Ribonuclease Oy|organism=Schmidtea mediterranea sexual|type=transcript|length=840bp
ATCTTGGAAAATATTTTATTAATTCCTTTATTATTTGTCGATGTCATCAT
CAATTAGAAAGTTCGTTTTGATTCTTACGATAGTTTGTGTGGAACTTCAG
GCCCGTCCACATACGGAGTGGGACTACCTGGTCTTTACACAGACATGGGC
GTCTACATTCTGTAAATTCAATAAATGCCATTTTCCATCCGATGCAATCA
GTCCGTGGACAATCCATGGATTGTGGCCTAGTAGAACTGTCGGTGCATTC
CCAGTTAATTGTTACCCAGGTCAGAAATTCAATGCCCAAAATATTGAAGA
TATTTATTCAACCTTAACTGTTGAATGGCCAAATCTATTAAACTTTGAGA
ACCCTATCCCATTCTGGACCCACGAGTGGTCAAAACATGGAACATGCTCA
CTAGATGACCCTATATTCACGAATGAGTTGTCTTACTTCCAAACTGGATT
AAATTTGAAATCAAAAATTGCAATTAAAAGTATCTTCTCCAGTAGCCAAA
TTGTTCAGAGTACCGATGAATCCTATAATACTTCTGATGTTGTAAACGCA
ATCCAAAGCGTTCTTCAAGTCAAATCAACATTAGAATGCGTCAAAATTGA
GAACCGATGGTATTTAAGTGCTGTTGAAATATGTCTCAACCGAAATCTGG
ATTTCATTGACTGCCCAAGACATAAAAAGAAGTCCATTCAATATTCTGAA
TACGAATCTTTGTATGAAAAAAGTTCTGATGCTGATATGGTAGGAAAAGT
AAATGACCAAAGACGAAAGGTGCAAGTTGCCAATATGCCTTGTGGTGATA
ACAGATTCTTCTTGCCTTGAAATTAAAATATAATCCTTTG
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protein sequence of SMED30005325-orf-1

>SMED30005325-orf-1 ID=SMED30005325-orf-1|Name=SMED30005325-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=260bp
MSSSIRKFVLILTIVCVELQARPHTEWDYLVFTQTWASTFCKFNKCHFPS
DAISPWTIHGLWPSRTVGAFPVNCYPGQKFNAQNIEDIYSTLTVEWPNLL
NFENPIPFWTHEWSKHGTCSLDDPIFTNELSYFQTGLNLKSKIAIKSIFS
SSQIVQSTDESYNTSDVVNAIQSVLQVKSTLECVKIENRWYLSAVEICLN
RNLDFIDCPRHKKKSIQYSEYESLYEKSSDADMVGKVNDQRRKVQVANMP
CGDNRFFLP*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR036430RNase_T2-like_sf
IPR033697Ribonuclease_T2_eukaryotic
IPR001568RNase_T2-like
IPR033130RNase_T2_His_AS_2
IPR018188RNase_T2_His_AS_1
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0033897ribonuclease T2 activity
Vocabulary: biological process
TermDefinition
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR036430Ribonuclease T2-like superfamilyGENE3DG3DSA:3.90.730.10coord: 19..250
e-value: 1.8E-56
score: 193.4
IPR036430Ribonuclease T2-like superfamilySUPERFAMILYSSF55895Ribonuclease Rh-likecoord: 27..214
IPR001568Ribonuclease T2-likePFAMPF00445Ribonuclease_T2coord: 27..208
e-value: 3.7E-48
score: 164.2
IPR001568Ribonuclease T2-likePANTHERPTHR11240RIBONUCLEASE T2coord: 10..230
NoneNo IPR availablePANTHERPTHR11240:SF22RIBONUCLEASE T2coord: 10..230
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.673
IPR033130Ribonuclease T2, His active site 2PROSITEPS00531RNASE_T2_2coord: 108..119
IPR018188Ribonuclease T2, His active site 1PROSITEPS00530RNASE_T2_1coord: 56..63
IPR033697Ribonuclease T2, eukaryoticCDDcd01061RNase_T2_eukcoord: 27..215
e-value: 1.48222E-57
score: 180.221