Ankyrin repeat domain 50
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30005209 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Ankyrin repeat domain 50 vs. Ensembl Human
Match: ANKRD50 (ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:HGNC:29223]) HSP 1 Score: 705.286 bits (1819), Expect = 0.000e+0 Identity = 393/1038 (37.86%), Postives = 601/1038 (57.90%), Query Frame = 2 Query: 266 LASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDE--NLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIE--VKGILPCEKFGSLNDWSIDDIVKILFESINLVN--------INKLNAKKSFTIFS----TYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 LA HFC A D D+L + FI + + +S + Y + + +L P AFK +LLPLL PP +++Y+L+DS+DE N+ GE+ S S ++ LL+ HH FFP WL L+C+ RK+++ + + F GFRK LDDL K+Y+++D+Q YIL+R+D+++ L+Q + ET E+LN LHIKS+G +YLE VLDG+++ ++ ++ I+ IPG L GLYLW+ + LF Q F V+ I N++L++ + L+ E+Y A+ +++ L + L + LV N H S EWLLDVK CT KY C+ +GH LA+ + L PL+ + FA HLI S + + A+W++++ + + ++P E+ +++++L ++ VN I + ++ +I + +N + ++ A YS SL + ++ L+ G D+ + +G T L +AA+ G T + N L+ GAN D+DGW+ALR A W G+ EVV LL + D D RTALR AAW G DIVL LL G+ +NK D+EGRT L+AA Y +V+ LL++GA ++H+D DGR+A+ VAALC+ ++ + ++ LL+ ++ D +GM LL+AAYEG + +LLE AD+D D R+PL+AAA G+ VV LLFWGAA+ ID G +VLSI+++QGN +++ LL RGLDE HRD+ G TPLH+A+ EG L++ GA+ NEIDN GRIP +L+ QEG+ + L++ +++ + YDG +L++A L + VE L S GAD +D +GR L+I L++Q + L+ N N+ D +GRTA+H++ W+G E+++ LI A ++ DNE R+ L AWQG ++ QLLI+ G +D TC+QGATAL IA+QEGH+++ +L+ GA+ H D RT +VA K H +I LLEK+GA Sbjct: 108 LAFHFCKAQDSDTLCVGGFIRGLVAQICRSGLL-QGYEDKLRDPAVQSLLQPGECERNPAEAFKRCVLLPLLGMKPPQQSLYLLVDSVDEGCNITE---GEQTSTSL-----------SGTVAALLAGHHEFFPPWLLLLCSARKQSKAVTKMFTGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAEMLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQ-FAKVQPILNVILAACRPLTITELYHAVWTKNMSLTLEDFQRKLDILSKLLVDGLGNTKILFHYSFAEWLLDVKHCTQKYLCNAAEGHRMLAMSYTCQAKNLTPLEAQEFALHLINSN--LQLETAELALWMIWNGTPVRDSLSTLIPKEQ----------EVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSL---------DVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLEN-KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLE-----NGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGA 1102 HSP 2 Score: 253.447 bits (646), Expect = 4.485e-68 Identity = 177/553 (32.01%), Postives = 288/553 (52.08%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAF-----SGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 L+ G +N +E+ TS +V LL +GA+ D +G + L A ++G ++VV LL+S+ D + G T L AA G T +V L+ G+NIN D +G T L +A + +V LL G +D D D R+A+ AA + DI+ LL++ +N DNEG L+ AAY G + + + LL++ A++ D+ R+ L AA G+ VV LL+ GA + DK G + L ++A +G+ ++ LL G D H DN G TPL A+ G VN LL GA + ID+ GR L ++ +G +++ L+D + N + G T L +A E L+ +GA DN+GR P ++ + YDC Q+LL+ N +NI+ DGR A+ +A+ +G +I++ L GA ++ KD +GR L++ A + + + ++ G N++ + ++G TAL ++ +GH+E+ +LI + A+V D+ R+ + A H+K+ LL +HGA+VD Sbjct: 500 LVKAGAHVN--SEDDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAW-----GGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE-NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE-----NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVD 1039 HSP 3 Score: 191.045 bits (484), Expect = 1.936e-48 Identity = 142/463 (30.67%), Postives = 229/463 (49.46%), Query Frame = 2 Query: 1979 DIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSC-----QEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +++ LL+ +G+++N +D + A + D + + LL+NGA ++ D++GR+ + AA S LD++ LL+ ++ + D G L +AA +G + L+ A+I+ D+ + L +AA+ G+ EVV LL+ G + C D + L +A G+ I+ LL G + DN G T L A+ G E V LL GA+ N D GR L ++ +G+ + LID E V+ DG T L +A + V+ LL GAD DNNGRTPL + LL ++ +D +GRT + IAS +G+ E++++L+D G + +D+ G T LH+ A++G IC+ LI+ G +E + G +ASQEGH + +L+ +N+ R +VA H I LL HGA V+ K+ Sbjct: 495 EVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSI--RTLLDNGASVNQCDSNGRTLLANAAY-----SGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAE-VDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA-----VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDA 944 HSP 4 Score: 152.91 bits (385), Expect = 1.235e-36 Identity = 99/303 (32.67%), Postives = 164/303 (54.13%), Query Frame = 2 Query: 1670 QNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVE 2569 Q + + L+ GLD N ++ G T L +AA G IC L+ GA ID DG LA G+ + V++LL K + D G DGR ALR AA G DIV LL S G+++N +D++GR L + M + L NGA ++ D +GR+A+ V+ C +++++++L+ Y+ ++N DNE + L AA++G + ++L+E+ A +D + L AA G+ +VV++LL GA + D+ G + + ++A G+SQI+ L G ++ GC+P + ++E Sbjct: 824 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVS--CWQG---HMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLN----GCSPSPVHTME 1117
BLAST of Ankyrin repeat domain 50 vs. Ensembl Human
Match: ANKRD50 (ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:HGNC:29223]) HSP 1 Score: 674.855 bits (1740), Expect = 0.000e+0 Identity = 370/963 (38.42%), Postives = 568/963 (58.98%), Query Frame = 2 Query: 491 PPNENMYILIDSIDE--NLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIE--VKGILPCEKFGSLNDWSIDDIVKILFESINLVN--------INKLNAKKSFTIFS----TYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 PP +++Y+L+DS+DE N+ GE+ S S ++ LL+ HH FFP WL L+C+ RK+++ + + F GFRK LDDL K+Y+++D+Q YIL+R+D+++ L+Q + ET E+LN LHIKS+G +YLE VLDG+++ ++ ++ I+ IPG L GLYLW+ + LF Q F V+ I N++L++ + L+ E+Y A+ +++ L + L + LV N H S EWLLDVK CT KY C+ +GH LA+ + L PL+ + FA HLI S + + A+W++++ + + ++P E+ +++++L ++ VN I + ++ +I + +N + ++ A YS SL + ++ L+ G D+ + +G T L +AA+ G T + N L+ GAN D+DGW+ALR A W G+ EVV LL + D D RTALR AAW G DIVL LL G+ +NK D+EGRT L+AA Y +V+ LL++GA ++H+D DGR+A+ VAALC+ ++ + ++ LL+ ++ D +GM LL+AAYEG + +LLE AD+D D R+PL+AAA G+ VV LLFWGAA+ ID G +VLSI+++QGN +++ LL RGLDE HRD+ G TPLH+A+ EG L++ GA+ NEIDN GRIP +L+ QEG+ + L++ +++ + YDG +L++A L + VE L S GAD +D +GR L+I L++Q + L+ N N+ D +GRTA+H++ W+G E+++ LI A ++ DNE R+ L AWQG ++ QLLI+ G +D TC+QGATAL IA+QEGH+++ +L+ GA+ H D RT +VA K H +I LLEK+GA Sbjct: 3 PPQQSLYLLVDSVDEGCNITE---GEQTSTSL-----------SGTVAALLAGHHEFFPPWLLLLCSARKQSKAVTKMFTGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAEMLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQ-FAKVQPILNVILAACRPLTITELYHAVWTKNMSLTLEDFQRKLDILSKLLVDGLGNTKILFHYSFAEWLLDVKHCTQKYLCNAAEGHRMLAMSYTCQAKNLTPLEAQEFALHLINSN--LQLETAELALWMIWNGTPVRDSLSTLIPKEQ----------EVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSL---------DVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLEN-KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLE-----NGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGA 923 HSP 2 Score: 253.832 bits (647), Expect = 1.892e-68 Identity = 177/553 (32.01%), Postives = 288/553 (52.08%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAF-----SGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 L+ G +N +E+ TS +V LL +GA+ D +G + L A ++G ++VV LL+S+ D + G T L AA G T +V L+ G+NIN D +G T L +A + +V LL G +D D D R+A+ AA + DI+ LL++ +N DNEG L+ AAY G + + + LL++ A++ D+ R+ L AA G+ VV LL+ GA + DK G + L ++A +G+ ++ LL G D H DN G TPL A+ G VN LL GA + ID+ GR L ++ +G +++ L+D + N + G T L +A E L+ +GA DN+GR P ++ + YDC Q+LL+ N +NI+ DGR A+ +A+ +G +I++ L GA ++ KD +GR L++ A + + + ++ G N++ + ++G TAL ++ +GH+E+ +LI + A+V D+ R+ + A H+K+ LL +HGA+VD Sbjct: 321 LVKAGAHVN--SEDDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAW-----GGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE-NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE-----NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVD 860 HSP 3 Score: 191.43 bits (485), Expect = 1.218e-48 Identity = 142/463 (30.67%), Postives = 229/463 (49.46%), Query Frame = 2 Query: 1979 DIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSC-----QEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +++ LL+ +G+++N +D + A + D + + LL+NGA ++ D++GR+ + AA S LD++ LL+ ++ + D G L +AA +G + L+ A+I+ D+ + L +AA+ G+ EVV LL+ G + C D + L +A G+ I+ LL G + DN G T L A+ G E V LL GA+ N D GR L ++ +G+ + LID E V+ DG T L +A + V+ LL GAD DNNGRTPL + LL ++ +D +GRT + IAS +G+ E++++L+D G + +D+ G T LH+ A++G IC+ LI+ G +E + G +ASQEGH + +L+ +N+ R +VA H I LL HGA V+ K+ Sbjct: 316 EVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSI--RTLLDNGASVNQCDSNGRTLLANAAY-----SGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAE-VDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA-----VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDA 765 HSP 4 Score: 153.295 bits (386), Expect = 8.479e-37 Identity = 99/303 (32.67%), Postives = 164/303 (54.13%), Query Frame = 2 Query: 1670 QNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVE 2569 Q + + L+ GLD N ++ G T L +AA G IC L+ GA ID DG LA G+ + V++LL K + D G DGR ALR AA G DIV LL S G+++N +D++GR L + M + L NGA ++ D +GR+A+ V+ C +++++++L+ Y+ ++N DNE + L AA++G + ++L+E+ A +D + L AA G+ +VV++LL GA + D+ G + + ++A G+SQI+ L G ++ GC+P + ++E Sbjct: 645 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVS--CWQG---HMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLN----GCSPSPVHTME 938
BLAST of Ankyrin repeat domain 50 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]) HSP 1 Score: 229.95 bits (585), Expect = 2.162e-60 Identity = 166/579 (28.67%), Postives = 278/579 (48.01%), Query Frame = 2 Query: 1604 STYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S YS S ++ + S + R I NG+DIN N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D + N K+ +G T L IA + +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L ++++EGH ++ L++ GA++ TP VA K +++ NLL + A D Sbjct: 24 SDYSRSSRKSDANA-SYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPD 586 HSP 2 Score: 210.69 bits (535), Expect = 2.228e-54 Identity = 169/638 (26.49%), Postives = 289/638 (45.30%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDD----------------------------DGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNH---IKICNLLEKHGALVDRK 3337 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG + + A L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A+ + + +PL A +V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L ++ + FLL GA +I G TPLH++ + + +LLQ S + + + L +G T +HIA+ K +I +L++ GA + +G +HL A +G + LL+ N++ + G T L +A+QE + + +L+N GA H+D+ + Y + G H IKI N L +H A V+ K Sbjct: 120 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGA---HVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAK 753 HSP 3 Score: 204.142 bits (518), Expect = 2.107e-52 Identity = 152/551 (27.59%), Postives = 257/551 (46.64%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL +N N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L +SA +G+ + + LL G G TPLH+A+ G+ E NLLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G T L A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 271 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG-ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 810 HSP 4 Score: 132.109 bits (331), Expect = 3.593e-30 Identity = 104/398 (26.13%), Postives = 186/398 (46.73%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVV+ LL GA+ + GF+ L+++ QG+ Q++S LL + LH+A+ + + LLL++ + G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL + I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D N + G T L IA ++ +++ LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 71 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDT----KGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRA-AAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 458
BLAST of Ankyrin repeat domain 50 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]) HSP 1 Score: 228.794 bits (582), Expect = 4.504e-60 Identity = 160/547 (29.25%), Postives = 268/547 (48.99%), Query Frame = 2 Query: 1700 IINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 I NG+DIN N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D + N K+ +G T L IA + +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L ++++EGH ++ L++ GA++ TP VA K +++ NLL + A D Sbjct: 44 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPD 575 HSP 2 Score: 217.624 bits (553), Expect = 1.479e-56 Identity = 163/618 (26.38%), Postives = 288/618 (46.60%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV*LFYVIDIG 3370 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG + + A L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A+ + + +PL A +V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L ++ + FLL GA +I G TPLH++ + + +LLQ S + + G T +H+A+ + ++ L+D GA G T LH+ A + I L+++G + + QG ++ +A+QEGH+++ +LL+ ANV + TP +A + + + + +L GA VD + + + +G Sbjct: 109 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSAS-----PDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG 720 HSP 3 Score: 203.756 bits (517), Expect = 2.907e-52 Identity = 152/551 (27.59%), Postives = 257/551 (46.64%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL +N N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L +SA +G+ + + LL G G TPLH+A+ G+ E NLLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G T L A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 260 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG-ASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 799 HSP 4 Score: 162.54 bits (410), Expect = 1.606e-39 Identity = 130/465 (27.96%), Postives = 213/465 (45.81%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ + N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L+ P+ T G TAL AA G+ ++V L+ G+ + + + +TPL + +V+ LL GA + G + L L++ + D+ LL + ++++ +G L +AA G + +LL+ +A D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G +HLA+ EG + V+LLL A N + G PL L+ QE + +AE L++ V+ ++ G T L + + V FLL A + NG TPLH + Q VLLQ++ + N +N G TA+ IA G ++ +L Sbjct: 345 DVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYT-----PLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG-AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVN-----GNTALGIARRLGYISVVDTL 798 HSP 5 Score: 132.109 bits (331), Expect = 3.787e-30 Identity = 104/398 (26.13%), Postives = 186/398 (46.73%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVV+ LL GA+ + GF+ L+++ QG+ Q++S LL + LH+A+ + + LLL++ + G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL + I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D N + G T L IA ++ +++ LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 60 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDT----KGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRA-AAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 447 HSP 6 Score: 129.413 bits (324), Expect = 2.533e-29 Identity = 110/408 (26.96%), Postives = 198/408 (48.53%), Query Frame = 2 Query: 2120 HQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIP-LMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQIC-QLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALV 3328 H+ G+ + A+ + + +L+ ++ +IN+ + G+N L +A+ EG + LL+ A++D + + L A+ +G EVV++L+ GA ++ ++GF+ L ++A + + +++ LL G + G TPL +A +G + V+LLL+ N+ R+P L ++ ++ K A L+ + + +S G T L IA LL+R A N TPLH++ + + ++LL I+ DG T +H + G ++++ L+D A I K G + LH+ A QG + C QLL+ + +D+ + TAL +A+ GH ++ +L++ AN TP +A K N IK+ LL KHGA + Sbjct: 14 HRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQ-NDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGA-----KIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHM-ATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASI 409
BLAST of Ankyrin repeat domain 50 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]) HSP 1 Score: 226.868 bits (577), Expect = 2.987e-59 Identity = 160/547 (29.25%), Postives = 268/547 (48.99%), Query Frame = 2 Query: 1700 IINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 I NG+DIN N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D + N K+ +G T L IA + +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L ++++EGH ++ L++ GA++ TP VA K +++ NLL + A D Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDK-KANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPD 592 HSP 2 Score: 215.312 bits (547), Expect = 1.181e-55 Identity = 172/664 (25.90%), Postives = 300/664 (45.18%), Query Frame = 2 Query: 1526 INLVNINKLNAKK--SFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKI-----------------------------DPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 IN+ N N LNA S + + +N AT + +L + + L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL + D G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG + + A L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A+ + + +PL A +V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L ++ + FLL GA +I G TPLH++ + + +LLQ S + + G T +H+A+ + ++ L+D GA G T LH+ A + I L+++G + + QG ++ +A+QEGH+++ +LL+ ANV + TP +A + + + + +L GA VD Sbjct: 67 INICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQ-QGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASP-----DAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVD 724 HSP 3 Score: 201.06 bits (510), Expect = 2.908e-51 Identity = 152/551 (27.59%), Postives = 257/551 (46.64%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL +N N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L +SA +G+ + + LL G G TPLH+A+ G+ E NLLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G T L A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 277 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD-QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 816 HSP 4 Score: 162.54 bits (410), Expect = 1.868e-39 Identity = 130/465 (27.96%), Postives = 213/465 (45.81%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ + N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L+ P+ T G TAL AA G+ ++V L+ G+ + + + +TPL + +V+ LL GA + G + L L++ + D+ LL + ++++ +G L +AA G + +LL+ +A D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G +HLA+ EG + V+LLL A N + G PL L+ QE + +AE L++ V+ ++ G T L + + V FLL A + NG TPLH + Q VLLQ++ + N +N G TA+ IA G ++ +L Sbjct: 362 DVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYT-----PLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAH-VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVN-----GNTALGIARRLGYISVVDTL 815 HSP 5 Score: 134.035 bits (336), Expect = 1.013e-30 Identity = 108/419 (25.78%), Postives = 196/419 (46.78%), Query Frame = 2 Query: 2096 LNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 + NG I+ + +G +A+ +A S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVV+ LL GA+ + GF+ L+++ QG+ Q++S LL R LH+A+ + + LLL++ + G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL + I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D N + G T L IA ++ +++ LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 61 IKNGVDINICNQNGLNALHLA-----SKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVR----LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNR-AAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 464 HSP 6 Score: 129.798 bits (325), Expect = 2.219e-29 Identity = 102/387 (26.36%), Postives = 175/387 (45.22%), Query Frame = 2 Query: 2354 MAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLN------------------RLPEF-----------VEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLID---------------------------------FGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALV 3328 + AA +G+ E + G I+ +++G + L +++ +G+ +++SELL R + G T LH+AS+ GQ E V +L+ +GA N +G PL ++ QE ++++ + L+D S + + DG T L +A+ RLP LL +A ++ +G TPLHI+ + +LL + + N + T +H+AS +G+ ++K L+D GA+ID K +G T LH GA G Q+ ++L+D + +D+ + TAL +A+ GH ++ +L++ AN TP +A K N IK+ LL KHGA + Sbjct: 46 LRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDN-GASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-----TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASI 426
BLAST of Ankyrin repeat domain 50 vs. Ensembl Celegans
Match: T28D6.4 (pep chromosome:WBcel235:III:11360456:11366214:1 gene:WBGene00012124.1 transcript:T28D6.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T28D6.4) HSP 1 Score: 228.409 bits (581), Expect = 3.305e-61 Identity = 169/528 (32.01%), Postives = 268/528 (50.76%), Query Frame = 2 Query: 1751 LMVAAQNGFTSICNLLLSSGANQLMIDKDG-WSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAA-IHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPL-HISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGA-RIDLKDNEGRTGLHLGAWQGCYQICQLLIDF-GINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 L+ AA G +C L + + G W+ALR A G +E++ LLL + +D D G+ RTALR AAW G+ V LLL +G+ ++++DSE RT LMAA + C +V +++ GA ++ D G +A+ + + + + KLLL +N + + D G L +AAY G L +++LE + +D++D ++PLM AA G E V+ L A + ID +G + L +A G+ +++ L + G DE H+DN G LH A E V L + D +G+ P+M++ G +K+ E L+ + + +N ++G T+L +A + ++ + R D + +D++G TPL H +L + +V L H N + D GRT +H+ + D K L +G + D GRT L W I L+D G++ + T QGATALSIA+Q G ++ NLL+ FGA DS RT VA + I +LL+ Sbjct: 428 LLTAAARGNIEMCRFLADHFPHLVASSCCGEWNALRSAACYGQLEILHLLLEKGVDVDECGHSDRTALRAAAWSGQLAAVQLLLQTGAEVDRRDSEQRTALMAAAFMCHKDVVSVIIQYGADVNAIDKSGATALHLNLSNGSKQEENSETTKLLLEHNADCKIEDANGRVALHLAAYHGDPCL-QLILEKHPIVDVMDNMGQTPLMLAASQGQLEAVQFLTKTAKADVDAIDNNGRTALQWAAINGHPEVVEFLCSVGSDEGHKDNDGAVALHYAVTHDHVELVKHLTNQHTVEAK-DRYGQHPMMIAAANGNLKVLEYLMGI-SDIINQPDHEGRTALSLASMAAHTSIIDLISPRITDWSQRDHDG-TPLAHTLILSNLIFVAEVYLGHGA-----NSSDSDAHGRTCVHVVASTNDVAAAKMLKRIGGVNFEAVDRGGRTALMTAVWAKHVAISVFLLDSCGVDPNRTDRQGATALSIAAQIGDRDLVNLLLKFGAEPEIKDSMGRTAMDVAMISGNEPIVSLLQ 946 HSP 2 Score: 126.716 bits (317), Expect = 3.231e-29 Identity = 131/516 (25.39%), Postives = 229/516 (44.38%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLM-----AATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLEN-NADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNIN--CLDDDGRTAIHIASWKGDGEIIKSLID-VGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLL 3208 L+ G+D++ + T+L AA +G + LLL +GA EV D ++ RTAL AA++ D+V +++ G+++N D G T L + + + KLLL + A +D +GR A+ +AA + ++L+L + ++++DN G L++AA +G + L + AD+D +D R+ L AA +G+ EVV L G+ D G L + + + +++ L + E +D +G P+ +A+ G + + L+ N+ D+ GR L L+ + I + LI + + +DG+ +L+ L E L GA+++ D +GRT +H+ + ++L + I +N +D GRTA+ A W I L+D G + D +G T L + A G + LL+ FG + S G TA+ +A G+ I +LL Sbjct: 477 LLEKGVDVDECGHSDRTALRAAAWSGQLAAVQLLLQTGA----------------------EV-----------DRRDSEQRTALMAAAFMCHKDVVSVIIQYGADVNAIDKSGATALHLNLSNGSKQEENSETTKLLLEHNADCKIEDANGRVALHLAAYHGDP------CLQLILEKHPIVDVMDNMGQTPLMLAASQGQLEAVQFLTKTAKADVDAIDNNGRTALQWAAINGHPEVVEFLCSVGSDEGHKDNDGAVALHYAVTHDHVELVKHLTNQHTVEA-KDRYGQHPMMIAAANGNLKVLEYLMGISDIINQPDHEGRTALSLASMAAHTSIID-LISPRITDWSQRDHDGTPLAHTLILSNLIFVAEVYLGHGANSSDSDAHGRTCVHVVASTNDVAAAKMLKR------IGGVNFEAVDRGGRTALMTAVWAKHVAISVFLLDSCGVDPNRTDRQGATALSIAAQIGDRDLVNLLLKFGAEPEIKDSMGRTAMDVAMISGNEPIVSLL 945 HSP 3 Score: 105.145 bits (261), Expect = 1.760e-22 Identity = 121/453 (26.71%), Postives = 193/453 (42.60%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNG-AYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYD--GSTSLKIAVLNRLPEFVEFLL-SRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDV 3019 + +S +I G D+N ++++G T+L +L LS+G+ Q E KLLL D +GR AL AA+ G + L+L ++ D+ G+TPLM A + V+ L A +D DN+GR+A+ AA+ + + ++++ L + DN+G L A L K L N ++ DR P+M AA +GN +V+ L+ I+ D G + LS+++ ++ I+ + R D RD+ G H + + L GA ++ D HGR + + + A+ L + VNF++ D G T+L AV + FLL S G D D G T L I+ D +LL+ I D GRTA+ +A G+ I+ L V Sbjct: 538 DVVSVIIQYGADVNAIDKSGATAL------------HLNLSNGSKQ----------------EENSETTKLLLEHNADCKIEDANGRVALHLAAYHG-DPCLQLILEKHPIVDVMDNMGQTPLMLAASQGQLEAVQFLTKTAKADVDAIDNNGRTALQWAAI-----NGHPEVVEFLCSVGSDEGHKDNDGAVALHYAVTHDHVELVK-HLTNQHTVEAKDRYGQHPMMIAAANGNLKVLEYLMGISDIINQPDHEGRTALSLASMAAHTSIIDLISPRITDWSQRDHDGTPLAHTLILSNLIFVAEVYLGHGANSSDSDAHGRTCVHVVASTNDVAAAKMLKRIG--GVNFEAVDRGGRTALMTAVWAKHVAISVFLLDSCGVDPNRTDRQGATALSIAAQIGDRDLVNLLLKFGAEPEIK-----DSMGRTAMDVAMISGNEPIVSLLQSV 948
BLAST of Ankyrin repeat domain 50 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 196.438 bits (498), Expect = 3.019e-50 Identity = 172/638 (26.96%), Postives = 274/638 (42.95%), Query Frame = 2 Query: 1688 ISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVV-----------------------------KLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLD----------------------------DDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 ++ L+ NG ++N + NG T L +AAQ + LL GANQ + +DG++ L +A+ G+ VV LLL + +PD T G T L AA G ++ LLL G+N+N Q +PL AT M LLL+ GA ID + D + + AA L + + ++D + LL + ++ + + + L +AA+ G + K+LL+ +AD + + +PL A +VV LLL + AAI +SG + L ++A G I+ LL +G + G TPLHLA+ Q + V +L+++GAK + + PL ++ + G I L+ S N + D + L IA E LL AD T+ G TPLH++ + ++LL+ +I N + +G T +HIA+ K EI +L+ A + K G T LHL A +G +I LLI+ G ++ + G TA+ + +QE H+ + +L N GA + + TP VA + + L ++GA V K Sbjct: 115 VTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANS-NATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEK 751 HSP 2 Score: 192.2 bits (487), Expect = 6.945e-49 Identity = 148/491 (30.14%), Postives = 231/491 (47.05%), Query Frame = 2 Query: 1745 TSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLL 3208 T L VAA G + LLL A+ +G++ L +A I+VV+LLL + + T G T L AA++G +IV+ LL G+N + + G TPL A +V++L+ NGA +D Q + ++ + +A+ N+ DI+ LLL+ N N + + L IAA EG + + ILL++NAD ++ + +PL A+ GN EVVRLLL G + K+ + L ++A N ++ LL G G TPLH+A+ + Q E + LL+ A PN G PL LS QEG+ +I+ LI+ G+D + NNG T +H+ + Q+L +N IN + G T +H+A G ++K L++ GA + K T LH A QG + L++ G + +E + G T LSIA + G++ + L Sbjct: 361 TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNT-----DIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE----------------------------------NGSDVGAKANNGLTAMHLCAQEDHVPVAQILY-----NNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 3 Score: 184.111 bits (466), Expect = 1.837e-46 Identity = 159/566 (28.09%), Postives = 267/566 (47.17%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMA---ATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLAR--GLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 SL + ++ + +LI ++ G T+L +A+ G + I +L+ +GAN + +G++ L +A + EVVK LL + + DG T L A G +V +LL + DS+G+ L A A K D LLL N D G + + +AA + + ++ +LLL N+N ++ L +A G + +LL A ID + +PL AA SG+ +VV LL+ GA I K+G + L ++A + LL +D++ D TPLH+A+ G LLL A PN +G PL ++C++ IK+ E L+ + ++ + G T L +A V +LL +GA+ ++ G TPLH++ +Q D +VL++ N ++ + +T +HIAS G+ +I+ L+ GA + + + LH+ A +G ++ +L+D + +G T L +AS+ G+LE+ LL+ G V TP VA N+ K+ LL ++GA Sbjct: 69 SLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL-------ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAA-----HYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYL--TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLK-YRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIR-----NGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGA 614 HSP 4 Score: 183.726 bits (465), Expect = 2.434e-46 Identity = 155/558 (27.78%), Postives = 261/558 (46.77%), Query Frame = 2 Query: 1739 GTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVA---------ALCLNSNSK------YLDI---------IKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 G+ S + AA+ G LL +G + + +G ++L LA G+ EVV+ L+ ++ D G TAL A+ G++ IV +L+ +G+N+N Q G TPL A + +VK LL +GA DG + + VA A+ L ++SK L I LLL+ N ++ G L IAA+ G + + ++LLE A+++ R SPL A G + LLL GA I K + L +A G+ Q++ L+ +G + G PLH+A+ + LL A +++ PL ++ G++++A+ L+D + N ++ +G T L IA + VE LL A +G TPLH++ + LLQ ++ + G T +H+A+ ++++ LI GA++D + E +T LH+ + G I LL+ G N + T + L IA++EG E+ +L++ A+ + TP +A K ++++ LL + G VD Sbjct: 33 GSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADP-NSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVR-----GETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVD 584 HSP 5 Score: 182.185 bits (461), Expect = 8.368e-46 Identity = 175/623 (28.09%), Postives = 285/623 (45.75%), Query Frame = 2 Query: 1496 DDIVKILFE--SINLVNINKLN--AKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLII-NGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMID---KDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV-KLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDE--MHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 D +V +L E S V + L+ AKK T +T +L ++ + T+ F+ + + QL++ G ++N + + L VA + G T++ NLLLS GA +ID KD + L A +G+ +VV LL+ Q +G L AA D LL + ++ + TPL A + C +V V KLLL+ A D + R+ L + + +++LLL+Y I G+ L +AA+ G+ + LL+ A+ D+ +PL AA + +VVR+L+ GA + + + L I++ GN+ I+ LL G + RDN+ +PLH+A+ EGQ E +LL A + G PL L+ + G +++ L++ V+ + + T L +A + LL GA A NG TPLHI+ ++Q + LLQ N + G T +H+++ +G EI LI+ G+ + K N G T +HL A + + Q+L + G I+ + G T L +A G L + L+ GA+V TP A + H L ++GA Sbjct: 178 DRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQ----NEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGA---IIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAH-CGHVRVAKLLLDRSA-----DPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNY--SPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLER-GTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKS-----RAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGA 779 HSP 6 Score: 174.096 bits (440), Expect = 2.723e-43 Identity = 150/546 (27.47%), Postives = 251/546 (45.97%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRI-PLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 N + L+ G I+ ++ T L AA++G + +LL+ GA K+G + L +A +++ + LL + D D T L AA G + LLL ++ N + G TPL A K +V+LLL A I+ G + + VAA ++I+ LL+ N ++ G L +AA + ++L+ N A +D R +PL A+ GN ++V LLL GA + + +S L I+A +G ++ LL D+ G TPLHLAS G E V LLL+ G P +I+ ++ PL ++ K+A L++ S + +G T L IA E LL AD + G TPLH+S + + +L++ N +++ ++G TA+H+ + + + + L + GA I+ K N G T LH+ G + + L++ G ++ E T L A+Q+GH L+ GA+ + +TP +A + ++ + L Sbjct: 274 NMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFM-----GAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLEN-GASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE-----NGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 7 Score: 143.665 bits (361), Expect = 4.791e-34 Identity = 105/347 (30.26%), Postives = 166/347 (47.84%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPL-MAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 R N + + LI NG ++ T L +A++ G T I LLL +GAN +D +S L +A G EV +LL D G T L A+ G ++V LLL G+ ++ + TPL +AA Y D V + LLL NGA +G + + +AA ++I LL++ + N G L ++A EG K + +L+EN +D+ + L A A + V ++L GA I+ +G++ L ++ G ++ L+ G D + TPLH A+ +G CV LL++GA PNE G+ PL ++ + GY+ + E L Sbjct: 467 RANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAM-LLLENGASAKAAAKNGYTPLHIAA-----KKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 8 Score: 107.842 bits (268), Expect = 4.155e-23 Identity = 103/441 (23.36%), Postives = 196/441 (44.44%), Query Frame = 2 Query: 2030 SEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +EG + A D V LL G I+ + +G +++ +A S + ++++ L++ ++ +G L IA+ G L+ IL+EN A++++ +PL AA + EVV+ LL GA + GF+ L+++ QG+ ++++ LL + + LH+A+ + LLL++ P+ G PL ++ G+ + + L++ +VN+++ + L +A LLSRGA + + TPLH + +L+ I+ +G +H+A+ + ++L+ A +D + T LH+ A G ++ +LL+D + + G T L IA ++ +++ LL+ + A + TP VA I I L + GA D + V Sbjct: 31 AEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLA-----SKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL----ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEK-GANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAP-----ISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETV 456
BLAST of Ankyrin repeat domain 50 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 196.438 bits (498), Expect = 3.019e-50 Identity = 172/638 (26.96%), Postives = 274/638 (42.95%), Query Frame = 2 Query: 1688 ISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVV-----------------------------KLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLD----------------------------DDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 ++ L+ NG ++N + NG T L +AAQ + LL GANQ + +DG++ L +A+ G+ VV LLL + +PD T G T L AA G ++ LLL G+N+N Q +PL AT M LLL+ GA ID + D + + AA L + + ++D + LL + ++ + + + L +AA+ G + K+LL+ +AD + + +PL A +VV LLL + AAI +SG + L ++A G I+ LL +G + G TPLHLA+ Q + V +L+++GAK + + PL ++ + G I L+ S N + D + L IA E LL AD T+ G TPLH++ + ++LL+ +I N + +G T +HIA+ K EI +L+ A + K G T LHL A +G +I LLI+ G ++ + G TA+ + +QE H+ + +L N GA + + TP VA + + L ++GA V K Sbjct: 115 VTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANS-NATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEK 751 HSP 2 Score: 192.2 bits (487), Expect = 6.945e-49 Identity = 148/491 (30.14%), Postives = 231/491 (47.05%), Query Frame = 2 Query: 1745 TSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLL 3208 T L VAA G + LLL A+ +G++ L +A I+VV+LLL + + T G T L AA++G +IV+ LL G+N + + G TPL A +V++L+ NGA +D Q + ++ + +A+ N+ DI+ LLL+ N N + + L IAA EG + + ILL++NAD ++ + +PL A+ GN EVVRLLL G + K+ + L ++A N ++ LL G G TPLH+A+ + Q E + LL+ A PN G PL LS QEG+ +I+ LI+ G+D + NNG T +H+ + Q+L +N IN + G T +H+A G ++K L++ GA + K T LH A QG + L++ G + +E + G T LSIA + G++ + L Sbjct: 361 TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNT-----DIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE----------------------------------NGSDVGAKANNGLTAMHLCAQEDHVPVAQILY-----NNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 3 Score: 184.111 bits (466), Expect = 1.837e-46 Identity = 159/566 (28.09%), Postives = 267/566 (47.17%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMA---ATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLAR--GLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 SL + ++ + +LI ++ G T+L +A+ G + I +L+ +GAN + +G++ L +A + EVVK LL + + DG T L A G +V +LL + DS+G+ L A A K D LLL N D G + + +AA + + ++ +LLL N+N ++ L +A G + +LL A ID + +PL AA SG+ +VV LL+ GA I K+G + L ++A + LL +D++ D TPLH+A+ G LLL A PN +G PL ++C++ IK+ E L+ + ++ + G T L +A V +LL +GA+ ++ G TPLH++ +Q D +VL++ N ++ + +T +HIAS G+ +I+ L+ GA + + + LH+ A +G ++ +L+D + +G T L +AS+ G+LE+ LL+ G V TP VA N+ K+ LL ++GA Sbjct: 69 SLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL-------ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAA-----HYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYL--TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLK-YRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIR-----NGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGA 614 HSP 4 Score: 183.726 bits (465), Expect = 2.434e-46 Identity = 155/558 (27.78%), Postives = 261/558 (46.77%), Query Frame = 2 Query: 1739 GTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVA---------ALCLNSNSK------YLDI---------IKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 G+ S + AA+ G LL +G + + +G ++L LA G+ EVV+ L+ ++ D G TAL A+ G++ IV +L+ +G+N+N Q G TPL A + +VK LL +GA DG + + VA A+ L ++SK L I LLL+ N ++ G L IAA+ G + + ++LLE A+++ R SPL A G + LLL GA I K + L +A G+ Q++ L+ +G + G PLH+A+ + LL A +++ PL ++ G++++A+ L+D + N ++ +G T L IA + VE LL A +G TPLH++ + LLQ ++ + G T +H+A+ ++++ LI GA++D + E +T LH+ + G I LL+ G N + T + L IA++EG E+ +L++ A+ + TP +A K ++++ LL + G VD Sbjct: 33 GSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADP-NSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVR-----GETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVD 584 HSP 5 Score: 182.185 bits (461), Expect = 8.368e-46 Identity = 175/623 (28.09%), Postives = 285/623 (45.75%), Query Frame = 2 Query: 1496 DDIVKILFE--SINLVNINKLN--AKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLII-NGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMID---KDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV-KLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDE--MHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 D +V +L E S V + L+ AKK T +T +L ++ + T+ F+ + + QL++ G ++N + + L VA + G T++ NLLLS GA +ID KD + L A +G+ +VV LL+ Q +G L AA D LL + ++ + TPL A + C +V V KLLL+ A D + R+ L + + +++LLL+Y I G+ L +AA+ G+ + LL+ A+ D+ +PL AA + +VVR+L+ GA + + + L I++ GN+ I+ LL G + RDN+ +PLH+A+ EGQ E +LL A + G PL L+ + G +++ L++ V+ + + T L +A + LL GA A NG TPLHI+ ++Q + LLQ N + G T +H+++ +G EI LI+ G+ + K N G T +HL A + + Q+L + G I+ + G T L +A G L + L+ GA+V TP A + H L ++GA Sbjct: 178 DRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQ----NEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGA---IIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAH-CGHVRVAKLLLDRSA-----DPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNY--SPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLER-GTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKS-----RAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGA 779 HSP 6 Score: 174.096 bits (440), Expect = 2.723e-43 Identity = 150/546 (27.47%), Postives = 251/546 (45.97%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRI-PLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 N + L+ G I+ ++ T L AA++G + +LL+ GA K+G + L +A +++ + LL + D D T L AA G + LLL ++ N + G TPL A K +V+LLL A I+ G + + VAA ++I+ LL+ N ++ G L +AA + ++L+ N A +D R +PL A+ GN ++V LLL GA + + +S L I+A +G ++ LL D+ G TPLHLAS G E V LLL+ G P +I+ ++ PL ++ K+A L++ S + +G T L IA E LL AD + G TPLH+S + + +L++ N +++ ++G TA+H+ + + + + L + GA I+ K N G T LH+ G + + L++ G ++ E T L A+Q+GH L+ GA+ + +TP +A + ++ + L Sbjct: 274 NMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFM-----GAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLEN-GASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE-----NGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 7 Score: 143.665 bits (361), Expect = 4.791e-34 Identity = 105/347 (30.26%), Postives = 166/347 (47.84%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPL-MAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 R N + + LI NG ++ T L +A++ G T I LLL +GAN +D +S L +A G EV +LL D G T L A+ G ++V LLL G+ ++ + TPL +AA Y D V + LLL NGA +G + + +AA ++I LL++ + N G L ++A EG K + +L+EN +D+ + L A A + V ++L GA I+ +G++ L ++ G ++ L+ G D + TPLH A+ +G CV LL++GA PNE G+ PL ++ + GY+ + E L Sbjct: 467 RANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAM-LLLENGASAKAAAKNGYTPLHIAA-----KKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 8 Score: 107.842 bits (268), Expect = 4.155e-23 Identity = 103/441 (23.36%), Postives = 196/441 (44.44%), Query Frame = 2 Query: 2030 SEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +EG + A D V LL G I+ + +G +++ +A S + ++++ L++ ++ +G L IA+ G L+ IL+EN A++++ +PL AA + EVV+ LL GA + GF+ L+++ QG+ ++++ LL + + LH+A+ + LLL++ P+ G PL ++ G+ + + L++ +VN+++ + L +A LLSRGA + + TPLH + +L+ I+ +G +H+A+ + ++L+ A +D + T LH+ A G ++ +LL+D + + G T L IA ++ +++ LL+ + A + TP VA I I L + GA D + V Sbjct: 31 AEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLA-----SKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL----ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEK-GANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAP-----ISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETV 456
BLAST of Ankyrin repeat domain 50 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 194.897 bits (494), Expect = 6.795e-50 Identity = 173/638 (27.12%), Postives = 273/638 (42.79%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVV-----------------------------KLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDND----------------------------GRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGR---IPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDD----------------------------DGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 L+ NG ++N + NG T L +AAQ + LL GANQ + +DG++ L +A+ G+ VV LLL + +PD T G T L AA G ++ LLL G+N+N Q +PL AT M LLL+ GA ID + D ++ +A L + + ++D + LL + ++ + + + L +AA+ G + K+LL+ +AD + + +PL A +VV LLL + AAI +SG + L ++A G I+ LL +G + G TPLHLA+ Q + V +L+++GAK +D R PL ++ + G I L+ S N + D + L IA E LL AD T+ G TPLH++ + ++LL+ +I N + +G T +HIA+ K EI +L+ A + K G T LHL A +G +I LLI+ G ++ + G TA+ + +QE H+ + +L N GA + + TP VA + + L ++GA V K Sbjct: 118 LVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAK---VDAQARELQTPLHIASRLGNTDIVILLLQAGANS-NATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEK 751 HSP 2 Score: 193.741 bits (491), Expect = 1.484e-49 Identity = 148/491 (30.14%), Postives = 231/491 (47.05%), Query Frame = 2 Query: 1745 TSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLL 3208 T L VAA G + LLL A+ +G++ L +A I+VV+LLL + + T G T L AA++G +IV+ LL G+N + + G TPL A +V++L+ NGA +D Q + ++ + +A+ N+ DI+ LLL+ N N + + L IAA EG + + ILL++NAD ++ + +PL A+ GN EVVRLLL G + K+ + L ++A N ++ LL G G TPLH+A+ + Q E + LL+ A PN G PL LS QEG+ +I+ LI+ G+D + NNG T +H+ + Q+L +N IN + G T +H+A G ++K L++ GA + K T LH A QG + L++ G + +E + G T LSIA + G++ + L Sbjct: 361 TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNT-----DIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE----------------------------------NGSDVGAKANNGLTAMHLCAQEDHVPVAQILY-----NNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 3 Score: 185.652 bits (470), Expect = 4.787e-47 Identity = 163/568 (28.70%), Postives = 269/568 (47.36%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMA---ATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELL--ARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDET--CSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 SL + ++ + +LI ++ G T+L +A+ G + I +L+ +GAN + +G++ L +A + EVVK LL + + DG T L A G +V +LL + DS+G+ L A A K D LLL N D G + + +AA + N + +LLL N+N ++ L +A G + +LL A ID + +PL AA SG+ +VV LL+ GA I K+G + L ++A + LL +D++ D TPLH+A+ G LLL A PN +G PL ++C++ IK+ E L+ + ++ + G T L +A V +LL +GA+ ++ G TPLH++ +Q D +VL++ N ++ + +T +HIAS G+ +I+ L+ GA + + + LH+ A +G ++ +L+D N D+T +G T L +AS+ G+LE+ LL+ G V TP VA N+ K+ LL ++GA Sbjct: 69 SLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN-------DSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHEN-----VGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYL--TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLK-YRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIR-----NGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDH--NADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGA 614 HSP 4 Score: 182.956 bits (463), Expect = 2.815e-46 Identity = 175/623 (28.09%), Postives = 285/623 (45.75%), Query Frame = 2 Query: 1496 DDIVKILFE--SINLVNINKLN--AKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIIN-GLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMID---KDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV-KLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDE--MHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 D +V +L E S V + L+ AKK T +T +L ++ + T+ F+ + + QL++ G ++N + + L VA + G T++ NLLLS GA +ID KD + L A +G+ +VV LL+ Q +G L AA D LL + ++ + TPL A + C +V V KLLL+ A D + R+ L + + +++LLL+Y I G+ L +AA+ G+ + LL+ A+ D+ +PL AA + +VVR+L+ GA + + + L I++ GN+ I+ LL G + RDN+ +PLH+A+ EGQ E +LL A + G PL L+ + G +++ L++ V+ + + T L +A + LL GA A NG TPLHI+ ++Q + LLQ + N G T +H+++ +G EI LI+ G+ + K N G T +HL A + + Q+L + G I+ + G T L +A G L + L+ GA+V TP A + H L ++GA Sbjct: 178 DRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQ----NEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGA---IIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAH-CGHVRVAKLLLDRSA-----DPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNY--SPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERG-TPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKA-----DPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGA 779 HSP 5 Score: 175.252 bits (443), Expect = 6.465e-44 Identity = 149/541 (27.54%), Postives = 249/541 (46.03%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRI-PLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 L+ G I+ ++ T L AA++G + +LL+ GA K+G + L +A +++ + LL + D D T L AA G + LLL ++ N + G TPL A K +V+LLL A I+ G + + VAA ++I+ LL+ N ++ G L +AA + ++L+ N A +D R +PL A+ GN ++V LLL GA + + +S L I+A +G ++ LL D+ G TPLHLAS G E V LLL+ G P +I+ ++ PL ++ K+A L++ S + +G T L IA E LL AD + G TPLH+S + + +L++ N +++ ++G TA+H+ + + + + L + GA I+ K N G T LH+ G + + L++ G ++ E T L A+Q+GH L+ GA+ + +TP +A + ++ + L Sbjct: 279 LLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFM-----GAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENG-ASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE-----NGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 6 Score: 145.591 bits (366), Expect = 9.114e-35 Identity = 105/349 (30.09%), Postives = 167/349 (47.85%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPL-MAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAA---AFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 + R N + + LI NG ++ T L +A++ G T I LLL +GAN +D +S L +A G EV +LL D G T L A+ G ++V LLL G+ ++ + TPL +AA Y D V + LLL NGA +G + + +AA ++I LL++ + N G L ++A EG K + +L+EN +D+ + L A A + V ++L GA I+ +G++ L ++ G ++ L+ G D + TPLH A+ +G CV LL++GA PNE G+ PL ++ + GY+ + E L Sbjct: 465 AARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAM-LLLENGASAKAAAKNGYTPLHIAA-----KKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 7 Score: 104.375 bits (259), Expect = 3.753e-22 Identity = 104/441 (23.58%), Postives = 195/441 (44.22%), Query Frame = 2 Query: 2030 SEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +EG + A D V LL G I+ + +G + +L L S + ++++ L++ ++ +G L IA+ G L+ IL+EN A++++ +PL AA + EVV+ LL GA + GF+ L+++ QG+ ++++ LL + + LH+A+ + LLL++ P+ G PL ++ G+ + + L++ +VN+++ + L +A LLSRGA + + TPLH + +L+ I+ +G +H+A+ + ++L+ A +D + T LH+ A G ++ +LL+D + + G T L IA ++ +++ LL+ + A + TP VA I I L + GA D + V Sbjct: 31 AEGSASFLRAARAGDLEKVLELLRAGTDINTSNANG-----LNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL----ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKG-ANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAP-----ISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETV 456
BLAST of Ankyrin repeat domain 50 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 194.897 bits (494), Expect = 6.795e-50 Identity = 173/638 (27.12%), Postives = 273/638 (42.79%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVV-----------------------------KLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDND----------------------------GRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGR---IPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDD----------------------------DGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 L+ NG ++N + NG T L +AAQ + LL GANQ + +DG++ L +A+ G+ VV LLL + +PD T G T L AA G ++ LLL G+N+N Q +PL AT M LLL+ GA ID + D ++ +A L + + ++D + LL + ++ + + + L +AA+ G + K+LL+ +AD + + +PL A +VV LLL + AAI +SG + L ++A G I+ LL +G + G TPLHLA+ Q + V +L+++GAK +D R PL ++ + G I L+ S N + D + L IA E LL AD T+ G TPLH++ + ++LL+ +I N + +G T +HIA+ K EI +L+ A + K G T LHL A +G +I LLI+ G ++ + G TA+ + +QE H+ + +L N GA + + TP VA + + L ++GA V K Sbjct: 118 LVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAK---VDAQARELQTPLHIASRLGNTDIVILLLQAGANS-NATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEK 751 HSP 2 Score: 193.741 bits (491), Expect = 1.484e-49 Identity = 148/491 (30.14%), Postives = 231/491 (47.05%), Query Frame = 2 Query: 1745 TSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLL 3208 T L VAA G + LLL A+ +G++ L +A I+VV+LLL + + T G T L AA++G +IV+ LL G+N + + G TPL A +V++L+ NGA +D Q + ++ + +A+ N+ DI+ LLL+ N N + + L IAA EG + + ILL++NAD ++ + +PL A+ GN EVVRLLL G + K+ + L ++A N ++ LL G G TPLH+A+ + Q E + LL+ A PN G PL LS QEG+ +I+ LI+ G+D + NNG T +H+ + Q+L +N IN + G T +H+A G ++K L++ GA + K T LH A QG + L++ G + +E + G T LSIA + G++ + L Sbjct: 361 TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNT-----DIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE----------------------------------NGSDVGAKANNGLTAMHLCAQEDHVPVAQILY-----NNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 3 Score: 185.652 bits (470), Expect = 4.787e-47 Identity = 163/568 (28.70%), Postives = 269/568 (47.36%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMA---ATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELL--ARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDET--CSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 SL + ++ + +LI ++ G T+L +A+ G + I +L+ +GAN + +G++ L +A + EVVK LL + + DG T L A G +V +LL + DS+G+ L A A K D LLL N D G + + +AA + N + +LLL N+N ++ L +A G + +LL A ID + +PL AA SG+ +VV LL+ GA I K+G + L ++A + LL +D++ D TPLH+A+ G LLL A PN +G PL ++C++ IK+ E L+ + ++ + G T L +A V +LL +GA+ ++ G TPLH++ +Q D +VL++ N ++ + +T +HIAS G+ +I+ L+ GA + + + LH+ A +G ++ +L+D N D+T +G T L +AS+ G+LE+ LL+ G V TP VA N+ K+ LL ++GA Sbjct: 69 SLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN-------DSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHEN-----VGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYL--TPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLK-YRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIR-----NGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDH--NADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGA 614 HSP 4 Score: 182.956 bits (463), Expect = 2.815e-46 Identity = 175/623 (28.09%), Postives = 285/623 (45.75%), Query Frame = 2 Query: 1496 DDIVKILFE--SINLVNINKLN--AKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIIN-GLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMID---KDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV-KLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDE--MHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 D +V +L E S V + L+ AKK T +T +L ++ + T+ F+ + + QL++ G ++N + + L VA + G T++ NLLLS GA +ID KD + L A +G+ +VV LL+ Q +G L AA D LL + ++ + TPL A + C +V V KLLL+ A D + R+ L + + +++LLL+Y I G+ L +AA+ G+ + LL+ A+ D+ +PL AA + +VVR+L+ GA + + + L I++ GN+ I+ LL G + RDN+ +PLH+A+ EGQ E +LL A + G PL L+ + G +++ L++ V+ + + T L +A + LL GA A NG TPLHI+ ++Q + LLQ + N G T +H+++ +G EI LI+ G+ + K N G T +HL A + + Q+L + G I+ + G T L +A G L + L+ GA+V TP A + H L ++GA Sbjct: 178 DRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQ----NEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGA---IIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAH-CGHVRVAKLLLDRSA-----DPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNY--SPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERG-TPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKA-----DPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGA 779 HSP 5 Score: 175.252 bits (443), Expect = 6.465e-44 Identity = 149/541 (27.54%), Postives = 249/541 (46.03%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRI-PLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 L+ G I+ ++ T L AA++G + +LL+ GA K+G + L +A +++ + LL + D D T L AA G + LLL ++ N + G TPL A K +V+LLL A I+ G + + VAA ++I+ LL+ N ++ G L +AA + ++L+ N A +D R +PL A+ GN ++V LLL GA + + +S L I+A +G ++ LL D+ G TPLHLAS G E V LLL+ G P +I+ ++ PL ++ K+A L++ S + +G T L IA E LL AD + G TPLH+S + + +L++ N +++ ++G TA+H+ + + + + L + GA I+ K N G T LH+ G + + L++ G ++ E T L A+Q+GH L+ GA+ + +TP +A + ++ + L Sbjct: 279 LLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFM-----GAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENG-ASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE-----NGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 6 Score: 145.591 bits (366), Expect = 9.114e-35 Identity = 105/349 (30.09%), Postives = 167/349 (47.85%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPL-MAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAA---AFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 + R N + + LI NG ++ T L +A++ G T I LLL +GAN +D +S L +A G EV +LL D G T L A+ G ++V LLL G+ ++ + TPL +AA Y D V + LLL NGA +G + + +AA ++I LL++ + N G L ++A EG K + +L+EN +D+ + L A A + V ++L GA I+ +G++ L ++ G ++ L+ G D + TPLH A+ +G CV LL++GA PNE G+ PL ++ + GY+ + E L Sbjct: 465 AARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAM-LLLENGASAKAAAKNGYTPLHIAA-----KKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807 HSP 7 Score: 104.375 bits (259), Expect = 3.753e-22 Identity = 104/441 (23.58%), Postives = 195/441 (44.22%), Query Frame = 2 Query: 2030 SEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +EG + A D V LL G I+ + +G + +L L S + ++++ L++ ++ +G L IA+ G L+ IL+EN A++++ +PL AA + EVV+ LL GA + GF+ L+++ QG+ ++++ LL + + LH+A+ + LLL++ P+ G PL ++ G+ + + L++ +VN+++ + L +A LLSRGA + + TPLH + +L+ I+ +G +H+A+ + ++L+ A +D + T LH+ A G ++ +LL+D + + G T L IA ++ +++ LL+ + A + TP VA I I L + GA D + V Sbjct: 31 AEGSASFLRAARAGDLEKVLELLRAGTDINTSNANG-----LNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL----ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKG-ANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAP-----ISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETV 456
BLAST of Ankyrin repeat domain 50 vs. Ensembl Fly
Match: CG10011 (gene:FBgn0039590 transcript:FBtr0085319) HSP 1 Score: 439.113 bits (1128), Expect = 2.633e-129 Identity = 239/553 (43.22%), Postives = 349/553 (63.11%), Query Frame = 2 Query: 1712 LDINCVNENGTTSLMVAAQNGFTSICNLLLS------SGANQLM------IDKDGWSALRLAIWNGYIEVVKLLLSQ---KIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKH 3316 +D+ + NG T+L +AA+NG + LLLS G ++ D+DGW+ LR A W G+ EVV+LL++Q KID +GRTALR AAW G DI+ LL+ SG+++N D +GRT L+AA+Y Y +V++LL NGA ++H D DGRSA+ VAALC +S Y +I LL + N + +DN+GM+ LL++++EG+ +C++LLEN AD D+ D R+PL AA +G+ VV+LLLFWG I C+D G +VLSI A+QGN + + +LL RGLDE HRDN G TPLH A+ EG +E LL+SGAK +E DN G+ L L+ QEG + + L+D+ V+ K++DG T+ ++A L + VEFLL D +D + RT L+I L+++ + + LL + N+ ++N D +GRTA+H+A+W+G +++K+LI+ GA ++ D E RT LH AWQG + + +L+ +G D C QGATAL I++QEGH + L+ FGAN D C RTP K+A K + I + E + Sbjct: 1262 IDLEIEDYNGQTALNIAARNGHLEVVKLLLSFSQPCNDGTGRMKRVDVNHADRDGWTPLRSASWGGHSEVVRLLIAQPACKID--LADKEGRTALRAAAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALC--GSSGYSKVISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVVKLLLFWGCGIDCMDSEGRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGAKIDECDNEGKTALHLAAQEGRLHCVQALLDIHSSFVDQKAHDGKTAFRLACLEGHMDTVEFLLKFCCDVNSKDADSRTTLYILALENKLEIVKYLLDMT---NV-DVNIPDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEARTPLHSCAWQGNHDVMNILLYYGALADHACKQGATALGISAQEGHEKCVIALLQFGANPYKSDHCGRTPIKLAAKSSRTSILKIFESY 1806 HSP 2 Score: 206.453 bits (524), Expect = 2.259e-53 Identity = 163/546 (29.85%), Postives = 264/546 (48.35%), Query Frame = 2 Query: 1829 DKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTG--NDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISA---SQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYD-CFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGAR-IDLKDNEGRTGLHLGAWQGCYQICQLLIDF----------------------------------GINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTP-YKVAYKGNHIKICNLLEKHGALVD 3331 D +G +AL +A NG++EVVKLLLS F+ NDG GR V ++N D +G TPL +A++ +V+LL+ A C I+L D EG L AA+ G + + K+L+E+ AD++ VDR + L+AA++ G++++V +LL GA ++ +D G S L ++A S G S+++S LL G + DN G +PL ++S EG E LLL++ A P+ D GR PL +C G+ + KL+ W ++ +G T L I E V LL RG D T +DN G TPLH + + ++ C Q+L + I+ D++G+TA+H+A+ +G +++L+D+ + +D K ++G+T L +G + L+ F ++++ S+G TAL +A+ +GH ++ LI GA+V +D RTP + A++GNH + N+L +GAL D Sbjct: 1268 DYNGQTALNIAARNGHLEVVKLLLS------FSQPCNDG---------TGRMKRV--------DVNHADRDGWTPLRSASWGGHSEVVRLLIAQPA-------------------------------------CKIDLADKEGRTALRAAAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVV-KLLLFWGCGIDCMDSEGRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGA------KIDECDNEGKTALHLAAQEGRLHCVQALLDIHSSFVDQKAHDGKTAFRLACLEGHMDTVEFLLKFCCDVNSKDADSRTTLYILALENKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEARTPLHSCAWQGNH-DVMNILLYYGALAD 1745 HSP 3 Score: 203.756 bits (517), Expect = 1.690e-52 Identity = 121/320 (37.81%), Postives = 181/320 (56.56%), Query Frame = 2 Query: 425 NLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSD-YLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFR--HNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASA 1375 N+ PD FK L PLL PP + +LIDSIDEN +++ L L T HK+R N+++LLS H + FP+WL LVCT +K+ + I + F GF+K LDDL KS+V++D+Q YI+NR++ D M+ E E L+ L+IKSNG I+YLE VL GI D + S + IK IP L GLYL+I + F Q ++ ++ + N++L+S + ++ L + D + L ++ L N + HNS +WL+DVK T K+ C + +GHV +++Y ++ L +R FA+HLI S Sbjct: 744 NIEKNPDECFKKAFLFPLLELTPPKTALLLLIDSIDENYINEGNLISTLKGGRGTVTNHKSR----NVAELLSNHIHLFPKWLFLVCTTKKQTKQITKMFTGFKKITLDDLRKSHVVKDVQEYIINRLNSDFKDSIMLTKEIIESLHQLYIKSNGCILYLEKVLHGIKDNFFSFREIKLIPCTLNGLYLYICQKSFNKKQ-YMKIRPLLNVLLASSGYVDKLFLFNCLRTHNYTIDCQEFEKRLQLMRNILAYDS-NAQRLKIFHNSFADWLVDVKFATKKFICDVNEGHVMISMYYLLVADTLCANTVRRFAYHLIRSG 1057 HSP 4 Score: 162.925 bits (411), Expect = 5.776e-40 Identity = 144/483 (29.81%), Postives = 222/483 (45.96%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIW---NGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGIN 3127 LI +G D+N V+ G TSL+ A+ G I +LL +GAN +D DG SAL +A +GY +V+ LL + D NDG + L +++ G ++ LLL + ++ + D GRTPL AA +VKLLL G ID D++GR+ + + A N ++ ++ LL + DN G L AA+EG +C LLE+ A ID D ++ L AA G +HC+ Q L ++ + +D+ D G T LA +EG + V LLK N D R L + E ++I + L+D+ VN +G T+L +A + V+ L+ GAD D RTPLH Q +D +LL + + + C G TA+ I++ +G + + +L+ GA D+ GRT + L A I ++ + N Sbjct: 1369 LIESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVVKLLLFWGCGIDCMDSEGRTVLSIGAAQGN-----VETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGAKIDECDNEGKTALHLAAQEGR-------------LHCV-----------------QALLDIHSSFVDQKAHD--GKTAFRLACLEGHMDTVEFLLKFCCDVNSKDADSRTTLYILALENKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEARTPLHSCAWQGNHDVMNILLYYGA---LADHAC--KQGATALGISAQEGHEKCVIALLQFGANPYKSDHCGRTPIKLAAKSSRTSILKIFESYTKN 1809 HSP 5 Score: 148.673 bits (374), Expect = 1.505e-35 Identity = 119/408 (29.17%), Postives = 202/408 (49.51%), Query Frame = 2 Query: 1499 DIVKILFESINLVNINKLNAKKSFTI--------FSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLN-NGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLE-NNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKI 2683 DIV+IL E+ VN L+ + + + +S I + +N+ + N L S + + L+ N D + + G T L A G ++ LLL G +D +G + L + G +E V+ LL + +D N G T L AA+ G ++ L LL SG+ I++ D+EG+T L A + V+ LL+ + +++D + +DG++A +A CL ++D ++ LL++ C++N D + L I A E + K LL+ N D++I D R+ L AA+ G+ ++V+ L+ GA ++ +D + L A QGN +++ LL G H G T L +++ EG +CV LL+ GA P + D+ GR P+ L+ + I Sbjct: 1397 DIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVVKLLLFWGCGIDCMDSEGRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGAKIDECDNEGKTALHLAAQEGRLHCVQALLDIHSSFVDQKAHDGKTAFRLA--CLEG---HMDTVEFLLKFCCDVNSKDADSRTTLYILALENKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEARTPLHSCAWQGNHDVMNILLYYGALADHACKQGATALGISAQEGHEKCVIALLQFGANPYKSDHCGRTPIKLAAKSSRTSI 1799
BLAST of Ankyrin repeat domain 50 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303119) HSP 1 Score: 218.394 bits (555), Expect = 1.464e-57 Identity = 165/564 (29.26%), Postives = 270/564 (47.87%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S + R + + + + N +DIN N NG +L +A+++G + + LL GA K G +AL +A G EVVKLLL + +G T L AA +V LLLS+G+N + +G TPL A + +V +LL ++D R + + AL + + + LLL + N ++ G L IA++ G++ + +L++ AD++ + SPL AA G +V LLL G I + G + L +A G+ Q++ LL RG + G PLH+A+ + +LL A +E+ L ++ G++++A+ L+D ++ N ++ +G T L IA + VE LL GA + +G TPLH++ + LLQH + ++ + G T +H+A+ +II+ L+ GA++D + E +T LH+ + G I LL+ G +D T TAL IA++EG E+ +LI GA + TP + K HIK+ LL + A VD Sbjct: 14 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLL---------ESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADA-NARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVR-----GETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVD 562 HSP 2 Score: 203.756 bits (517), Expect = 5.763e-53 Identity = 159/550 (28.91%), Postives = 259/550 (47.09%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAAL--CLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 N +S L+ G +I +G T L AA++G + ++LL GA K+G + L +A +++ ++LL + D D TAL AA G + LLL ++ N + G TPL A K +V+LLL +GA I G + + VAA C+N I+ LL+++ + ++ G L +AA + +ILL N A +D R +PL A+ GN ++V LLL GA + K ++ L I+A +G ++ + L+ G LD + F TPLHL + G + LLL+ A + +G PL ++C ++A L++ S + + +G T L IA + LL GA A + G TPLH+S + + +L++H +N +G T +H+ + + + + + L GA ID+ G T LH+ + G + + L+ G N+D S G T L +Q+GH I NLL+ AN +TP +A K +I + + L+ Sbjct: 252 NMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMN-------IVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGF--TPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKG-ASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAA-----VNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLK 786 HSP 3 Score: 203.371 bits (516), Expect = 7.615e-53 Identity = 169/633 (26.70%), Postives = 282/633 (44.55%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALR---------------------------------TAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV*LFYVIDIGFSSYYILNSF 3400 L+ + +N ++NG T L +AAQ ++ LLLS+GANQ + +DG++ L +A+ G+ +VV +LL ++K D PD T G T L AA G+T++V LLL G NI + +G TPL A +V +LL GA I + +G +A L + + +++D ++LL + ++ + + + L +AA+ G + K+LL+ NAD + + +PL A +VV LLL GA+I +SG + L ++A G I+ LL G TPLHLA+ Q + + +LL++GA+ + + PL ++ + G + I L+ + V+ + D T+L IA E L+ GA G TPLH++ Q+LLQ +++ +G T +H+A + ++ L++ GA G T LH+ A + I L+++G + G T L ++SQEGH EI NLLI A V H TP + + +++ + +LEK+GA +D G++ ++ + F Sbjct: 96 LLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNG-----LAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQ-VDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEA-----DVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANID-------MATKAGYTPLHVASHF 710 HSP 4 Score: 200.29 bits (508), Expect = 7.320e-52 Identity = 176/627 (28.07%), Postives = 291/627 (46.41%), Query Frame = 2 Query: 1496 DDIVKILFESINLVNIN----KLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIIN-GLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV-KLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 D +V +L ES + + AKK +T +L+ ++ + T+ F+ I+ L+I G D+N ++ + L VAA+ G T++ +LLL G N +DG + L A +G+ +VV +LL + +G L AA D +LL + +++ + T L A + C +V V KLLL+ A D + R+ L + L +++LLLR+ +I+ G+ L +AA+ G + LL+++A D+ +PL AA + +++R+LL GA + + + L I++ GN I+ LL G +D +D + T LH+A+ EGQ E +L+++GA + G PL L+ + G+IK+A+ L+ + V+ + +G T L +A + LL +GA NG TPLHI+ ++Q D LL++ N G T +H++S +G EI LI+ A ++ G T +HL A + + ++L G NID G T L +AS G + L+ GANV S TP + H I NLL +H A + + V Sbjct: 156 DKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLD----NDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAH-CGHVRVAKLLLDRNA-----DANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY--TALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEAD-VDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGAL-----ANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTV 764 HSP 5 Score: 125.561 bits (314), Expect = 1.231e-28 Identity = 97/354 (27.40%), Postives = 158/354 (44.63%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPE 2713 + R N + I L+ NG ++ T L +A++ G I LLL GA KD ++AL +A G EV +L+ D G T L A G + LLL ++++ Q G TPL A + + + LLL GA +G + + +AA +DI LL Y N G L +++ EG + +L+E+ A ++ + +P+ A N V +L GA I K+G++ L +++ G + ++ LL G + + G TPLH + +G VNLLL+ A N +G+ PL ++ + GYI + + L + E Sbjct: 443 AARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAA-----RKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKE 791 HSP 6 Score: 115.546 bits (288), Expect = 1.515e-25 Identity = 99/348 (28.45%), Postives = 156/348 (44.83%), Query Frame = 2 Query: 2303 ILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTP-LHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 ++ EN A D + + AA +GN E V L I+ + +G + L +++ G+ ++SELL RG G T LH+AS+ GQ E V LLL+ A N +G PL ++ QE + + L+ + + DG T L +A+ + V LL + R P LHI+ + +LL N +N + G T +HIAS G+ I LI GA ++ + LH+ A G + LL++ G NI+ G T L A++ GH ++ ++L+ GA + P +A +G H+ +L H A VD V Sbjct: 1 MVTENGAQGD--GNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQ-SLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKV-----RLPALHIAAKKDDVKAATLLLD-----NDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTV 335
BLAST of Ankyrin repeat domain 50 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0334061) HSP 1 Score: 217.238 bits (552), Expect = 4.734e-57 Identity = 169/568 (29.75%), Postives = 276/568 (48.59%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIA-VLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMR---TPYKVAYKGNHIKICNLLEKHGALVD 3331 S + R + + + + N +DIN N NG +L +A+++G + + LL GA K G +AL +A G EVVKLLL + +G T L AA +V LLLS+G+N + +G TPL A + +V +LL ++D R + + AL + + + LLL + N ++ G L IA++ G++ + +L++ AD++ + SPL AA G +V LLL G I + G + L +A G+ Q++ LL RG + G PLH+A+ + +LL A +E+ L ++ G++++A+ L+D ++ N ++ +G T L IA NRL + VE LL GA + +G TPLH++ + LLQH + ++ + G T +H+A+ +II+ L+ GA++D + E +T LH+ + G I LL+ G +D T TAL IA++EG E+ +LI GA +D+ + TP + K HIK+ LL + A VD Sbjct: 164 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLL---------ESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADA-NARALNGFTPLHIACKKNRL-KVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVR-----GETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAA---LDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVD 712 HSP 2 Score: 203.756 bits (517), Expect = 8.610e-53 Identity = 159/550 (28.91%), Postives = 259/550 (47.09%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAAL--CLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 N +S L+ G +I +G T L AA++G + ++LL GA K+G + L +A +++ ++LL + D D TAL AA G + LLL ++ N + G TPL A K +V+LLL +GA I G + + VAA C+N I+ LL+++ + ++ G L +AA + +ILL N A +D R +PL A+ GN ++V LLL GA + K ++ L I+A +G ++ + L+ G LD + F TPLHL + G + LLL+ A + +G PL ++C ++A L++ S + + +G T L IA + LL GA A + G TPLH+S + + +L++H +N +G T +H+ + + + + + L GA ID+ G T LH+ + G + + L+ G N+D S G T L +Q+GH I NLL+ AN +TP +A K +I + + L+ Sbjct: 402 NMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMN-------IVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGF--TPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKG-ASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAA-----VNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLK 936 HSP 3 Score: 202.986 bits (515), Expect = 1.386e-52 Identity = 169/633 (26.70%), Postives = 282/633 (44.55%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALR---------------------------------TAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV*LFYVIDIGFSSYYILNSF 3400 L+ + +N ++NG T L +AAQ ++ LLLS+GANQ + +DG++ L +A+ G+ +VV +LL ++K D PD T G T L AA G+T++V LLL G NI + +G TPL A +V +LL GA I + +G +A L + + +++D ++LL + ++ + + + L +AA+ G + K+LL+ NAD + + +PL A +VV LLL GA+I +SG + L ++A G I+ LL G TPLHLA+ Q + + +LL++GA+ + + PL ++ + G + I L+ + V+ + D T+L IA E L+ GA G TPLH++ Q+LLQ +++ +G T +H+A + ++ L++ GA G T LH+ A + I L+++G + G T L ++SQEGH EI NLLI A V H TP + + +++ + +LEK+GA +D G++ ++ + F Sbjct: 246 LLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNG-----LAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQ-VDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEA-----DVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANID-------MATKAGYTPLHVASHF 860 HSP 4 Score: 200.675 bits (509), Expect = 9.138e-52 Identity = 176/627 (28.07%), Postives = 291/627 (46.41%), Query Frame = 2 Query: 1496 DDIVKILFESINLVNIN----KLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIIN-GLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV-KLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 D +V +L ES + + AKK +T +L+ ++ + T+ F+ I+ L+I G D+N ++ + L VAA+ G T++ +LLL G N +DG + L A +G+ +VV +LL + +G L AA D +LL + +++ + T L A + C +V V KLLL+ A D + R+ L + L +++LLLR+ +I+ G+ L +AA+ G + LL+++A D+ +PL AA + +++R+LL GA + + + L I++ GN I+ LL G +D +D + T LH+A+ EGQ E +L+++GA + G PL L+ + G+IK+A+ L+ + V+ + +G T L +A + LL +GA NG TPLHI+ ++Q D LL++ N G T +H++S +G EI LI+ A ++ G T +HL A + + ++L G NID G T L +AS G + L+ GANV S TP + H I NLL +H A + + V Sbjct: 306 DKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLD----NDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAH-CGHVRVAKLLLDRNA-----DANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY--TALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEAD-VDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGAL-----ANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTV 914 HSP 5 Score: 126.331 bits (316), Expect = 8.728e-29 Identity = 97/354 (27.40%), Postives = 158/354 (44.63%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPE 2713 + R N + I L+ NG ++ T L +A++ G I LLL GA KD ++AL +A G EV +L+ D G T L A G + LLL ++++ Q G TPL A + + + LLL GA +G + + +AA +DI LL Y N G L +++ EG + +L+E+ A ++ + +P+ A N V +L GA I K+G++ L +++ G + ++ LL G + + G TPLH + +G VNLLL+ A N +G+ PL ++ + GYI + + L + E Sbjct: 593 AARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAA-----RKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKE 941 HSP 6 Score: 112.464 bits (280), Expect = 1.427e-24 Identity = 95/332 (28.61%), Postives = 150/332 (45.18%), Query Frame = 2 Query: 2351 LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTP-LHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 + AA +GN E V L I+ + +G + L +++ G+ ++SELL RG G T LH+AS+ GQ E V LLL+ A N +G PL ++ QE + + L+ + + + DG T L +A+ + V LL + R P LHI+ + +LL N +N + G T +HIAS G+ I LI GA ++ + LH+ A G + LL++ G NI+ G T L A++ GH ++ ++L+ GA + P +A +G H+ +L H A VD V Sbjct: 165 FLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNG-ANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKV-----RLPALHIAAKKDDVKAATLLLD-----NDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTV 485
BLAST of Ankyrin repeat domain 50 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303117) HSP 1 Score: 217.238 bits (552), Expect = 1.410e-56 Identity = 165/564 (29.26%), Postives = 270/564 (47.87%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S + R + + + + N +DIN N NG +L +A+++G + + LL GA K G +AL +A G EVVKLLL + +G T L AA +V LLLS+G+N + +G TPL A + +V +LL ++D R + + AL + + + LLL + N ++ G L IA++ G++ + +L++ AD++ + SPL AA G +V LLL G I + G + L +A G+ Q++ LL RG + G PLH+A+ + +LL A +E+ L ++ G++++A+ L+D ++ N ++ +G T L IA + VE LL GA + +G TPLH++ + LLQH + ++ + G T +H+A+ +II+ L+ GA++D + E +T LH+ + G I LL+ G +D T TAL IA++EG E+ +LI GA + TP + K HIK+ LL + A VD Sbjct: 14 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLL---------ESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADA-NARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVR-----GETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVD 562 HSP 2 Score: 200.675 bits (509), Expect = 2.100e-51 Identity = 159/550 (28.91%), Postives = 259/550 (47.09%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAAL--CLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 N +S L+ G +I +G T L AA++G + ++LL GA K+G + L +A +++ ++LL + D D TAL AA G + LLL ++ N + G TPL A K +V+LLL +GA I G + + VAA C+N I+ LL+++ + ++ G L +AA + +ILL N A +D R +PL A+ GN ++V LLL GA + K ++ L I+A +G ++ + L+ G LD + F TPLHL + G + LLL+ A + +G PL ++C ++A L++ S + + +G T L IA + LL GA A + G TPLH+S + + +L++H +N +G T +H+ + + + + + L GA ID+ G T LH+ + G + + L+ G N+D S G T L +Q+GH I NLL+ AN +TP +A K +I + + L+ Sbjct: 252 NMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMN-------IVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGF--TPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEK-GASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAA-----VNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLK 786 HSP 3 Score: 200.29 bits (508), Expect = 2.693e-51 Identity = 163/605 (26.94%), Postives = 280/605 (46.28%), Query Frame = 2 Query: 1613 SNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSG--------------------ANQLMIDKD---------GWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S ++++ N ++ L+ + ++N + L+ NG + + E+G T L VA Q G + +LL S A L++D D G++ L +A G + LL+ + D +++ + L AA G+T++V LLL G NI + +G TPL A +V +LL GA I + +G + + +AA +++D ++LL + ++ + + + L +AA+ G + K+LL+ NAD + + +PL A +VV LLL GA+I +SG + L ++A G I+ LL G TPLHLA+ Q + + +LL++GA+ + + PL ++ + G + I L+ + V+ + D T+L IA E L+ GA G TPLH++ Q+LLQ +++ +G T +H+A + ++ L++ GA G T LH+ A + I L+++G + G T L ++SQEGH EI NLLI A V H TP + + +++ + +LEK+GA +D Sbjct: 102 SVNVQSQNGFT-PLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAA-----QGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQ-VDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEA-----DVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANID 694 HSP 4 Score: 198.749 bits (504), Expect = 7.397e-51 Identity = 167/598 (27.93%), Postives = 279/598 (46.66%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALC-------------LNSNSKYLD---------------IIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +L + +++ + L+ N + + +++G T L +A+ G +I NLL+ GA+ K S L +A G +V LLL + + + DG T L AA G +V +LL G+ I+ + G PL A ++LL + A +D D +A+ VAA C ++N++ L+ +++LLLR+ +I+ G+ L +AA+ G + LL+++A D+ +PL AA + +++R+LL GA + + + L I++ GN I+ LL G +D +D + T LH+A+ EGQ E +L+++GA + G PL L+ + G+IK+A+ L+ + V+ + +G T L +A + LL +GA NG TPLHI+ ++Q D LL++ N + G T +H++S +G EI LI+ A ++ G T +HL A + + ++L G NID G T L +AS G + L+ GANV S TP + H I NLL +H A + + V Sbjct: 175 ALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY--TALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEAD-VDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAES-----KAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTV 764 HSP 5 Score: 123.25 bits (308), Expect = 9.763e-28 Identity = 97/352 (27.56%), Postives = 157/352 (44.60%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPE 2713 R N + I L+ NG ++ T L +A++ G I LLL GA KD ++AL +A G EV +L+ D G T L A G + LLL ++++ Q G TPL A + + + LLL GA +G + + +AA +DI LL Y N G L +++ EG + +L+E+ A ++ + +P+ A N V +L GA I K+G++ L +++ G + ++ LL G + + G TPLH + +G VNLLL+ A N +G+ PL ++ + GYI + + L + E Sbjct: 445 RANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAA-----RKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKE 791 HSP 6 Score: 116.316 bits (290), Expect = 1.379e-25 Identity = 99/348 (28.45%), Postives = 156/348 (44.83%), Query Frame = 2 Query: 2303 ILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTP-LHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 ++ EN A D + + AA +GN E V L I+ + +G + L +++ G+ ++SELL RG G T LH+AS+ GQ E V LLL+ A N +G PL ++ QE + + L+ + + DG T L +A+ + V LL + R P LHI+ + +LL N +N + G T +HIAS G+ I LI GA ++ + LH+ A G + LL++ G NI+ G T L A++ GH ++ ++L+ GA + P +A +G H+ +L H A VD V Sbjct: 1 MVTENGAQGD--GNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQ-SLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKV-----RLPALHIAAKKDDVKAATLLLD-----NDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTV 335
BLAST of Ankyrin repeat domain 50 vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303121) HSP 1 Score: 217.238 bits (552), Expect = 1.413e-56 Identity = 165/564 (29.26%), Postives = 270/564 (47.87%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S + R + + + + N +DIN N NG +L +A+++G + + LL GA K G +AL +A G EVVKLLL + +G T L AA +V LLLS+G+N + +G TPL A + +V +LL ++D R + + AL + + + LLL + N ++ G L IA++ G++ + +L++ AD++ + SPL AA G +V LLL G I + G + L +A G+ Q++ LL RG + G PLH+A+ + +LL A +E+ L ++ G++++A+ L+D ++ N ++ +G T L IA + VE LL GA + +G TPLH++ + LLQH + ++ + G T +H+A+ +II+ L+ GA++D + E +T LH+ + G I LL+ G +D T TAL IA++EG E+ +LI GA + TP + K HIK+ LL + A VD Sbjct: 14 SFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLL---------ESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADA-NARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVR-----GETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVD 562 HSP 2 Score: 200.675 bits (509), Expect = 2.104e-51 Identity = 159/550 (28.91%), Postives = 259/550 (47.09%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAAL--CLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 N +S L+ G +I +G T L AA++G + ++LL GA K+G + L +A +++ ++LL + D D TAL AA G + LLL ++ N + G TPL A K +V+LLL +GA I G + + VAA C+N I+ LL+++ + ++ G L +AA + +ILL N A +D R +PL A+ GN ++V LLL GA + K ++ L I+A +G ++ + L+ G LD + F TPLHL + G + LLL+ A + +G PL ++C ++A L++ S + + +G T L IA + LL GA A + G TPLH+S + + +L++H +N +G T +H+ + + + + + L GA ID+ G T LH+ + G + + L+ G N+D S G T L +Q+GH I NLL+ AN +TP +A K +I + + L+ Sbjct: 252 NMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMN-------IVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGF--TPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEK-GASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAA-----VNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLK 786 HSP 3 Score: 200.29 bits (508), Expect = 2.698e-51 Identity = 163/605 (26.94%), Postives = 280/605 (46.28%), Query Frame = 2 Query: 1613 SNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSG--------------------ANQLMIDKD---------GWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S ++++ N ++ L+ + ++N + L+ NG + + E+G T L VA Q G + +LL S A L++D D G++ L +A G + LL+ + D +++ + L AA G+T++V LLL G NI + +G TPL A +V +LL GA I + +G + + +AA +++D ++LL + ++ + + + L +AA+ G + K+LL+ NAD + + +PL A +VV LLL GA+I +SG + L ++A G I+ LL G TPLHLA+ Q + + +LL++GA+ + + PL ++ + G + I L+ + V+ + D T+L IA E L+ GA G TPLH++ Q+LLQ +++ +G T +H+A + ++ L++ GA G T LH+ A + I L+++G + G T L ++SQEGH EI NLLI A V H TP + + +++ + +LEK+GA +D Sbjct: 102 SVNVQSQNGFT-PLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAA-----QGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQ-VDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEA-----DVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANID 694 HSP 4 Score: 198.749 bits (504), Expect = 7.412e-51 Identity = 167/598 (27.93%), Postives = 279/598 (46.66%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALC-------------LNSNSKYLD---------------IIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +L + +++ + L+ N + + +++G T L +A+ G +I NLL+ GA+ K S L +A G +V LLL + + + DG T L AA G +V +LL G+ I+ + G PL A ++LL + A +D D +A+ VAA C ++N++ L+ +++LLLR+ +I+ G+ L +AA+ G + LL+++A D+ +PL AA + +++R+LL GA + + + L I++ GN I+ LL G +D +D + T LH+A+ EGQ E +L+++GA + G PL L+ + G+IK+A+ L+ + V+ + +G T L +A + LL +GA NG TPLHI+ ++Q D LL++ N + G T +H++S +G EI LI+ A ++ G T +HL A + + ++L G NID G T L +AS G + L+ GANV S TP + H I NLL +H A + + V Sbjct: 175 ALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMY--TALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEAD-VDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAES-----KAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTV 764 HSP 5 Score: 123.25 bits (308), Expect = 9.775e-28 Identity = 97/352 (27.56%), Postives = 157/352 (44.60%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPE 2713 R N + I L+ NG ++ T L +A++ G I LLL GA KD ++AL +A G EV +L+ D G T L A G + LLL ++++ Q G TPL A + + + LLL GA +G + + +AA +DI LL Y N G L +++ EG + +L+E+ A ++ + +P+ A N V +L GA I K+G++ L +++ G + ++ LL G + + G TPLH + +G VNLLL+ A N +G+ PL ++ + GYI + + L + E Sbjct: 445 RANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAA-----RKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKE 791 HSP 6 Score: 116.316 bits (290), Expect = 1.381e-25 Identity = 99/348 (28.45%), Postives = 156/348 (44.83%), Query Frame = 2 Query: 2303 ILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTP-LHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 ++ EN A D + + AA +GN E V L I+ + +G + L +++ G+ ++SELL RG G T LH+AS+ GQ E V LLL+ A N +G PL ++ QE + + L+ + + DG T L +A+ + V LL + R P LHI+ + +LL N +N + G T +HIAS G+ I LI GA ++ + LH+ A G + LL++ G NI+ G T L A++ GH ++ ++L+ GA + P +A +G H+ +L H A VD V Sbjct: 1 MVTENGAQGD--GNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQ-SLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKV-----RLPALHIAAKKDDVKAATLLLD-----NDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTV 335
BLAST of Ankyrin repeat domain 50 vs. Ensembl Zebrafish
Match: ANKRD50 (ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:HGNC:29223]) HSP 1 Score: 550.051 bits (1416), Expect = 7.538e-176 Identity = 316/838 (37.71%), Postives = 483/838 (57.64%), Query Frame = 2 Query: 854 LLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVN----------INKLNAKKSFTIFSTYILNITSTYSN--SIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 +LN LHIKS+G +YLE VLDG+++ ++ ++ I+ IPG L GLYLW+ + LF Q F V+ I N++L++ + L+ +E+Y A+ ++ + + + + L+ + H S EWLLDVK CT KY C+ +GH +A+ + +L PL+++ FA HLI S + + ++ A+W++++ P + S + +++++L ++ V+ L + S ++ T SN ++ A YS +L ++ LI ++ V+ +G T+L +AA+ G T + N L+ AN D DGW+ALR A W G+ EVV LL D D RTALR AAW G DIVL LL G+ +NK D+EGRT L+AA Y +V+ LL++GA ++H+D DGR+A+ VAALC+ ++ + ++ LL+ ++ D + M LL+AAYEG + +LLE AD+D D R+PL+AAA G+ VV LLFWGAA+ ID G +VLSI+++QGN +++ LL RGLDE HRD+ G TPLH+AS EG + + L++ G++ E+DN GRIPL+LS QEG+ L++ ++ + YDG +L++A L + VE LLS AD +D +GR L+I L++Q + L+ N N+ D +GRTA+H++ W+G E+++ LI+ A ++ DNE R+ L AWQG +I Q LID G +D TC+QGATAL IA+QEGH+E+ +L+ A+ H D RT +VA KG H I LLEK+GA Sbjct: 1 MLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQ-FAKVQPILNVILAACRPLTVRELYHAVWTKNMTLTMEDFQKKMDILAKLLIDGLGSTKILFHYSFAEWLLDVKHCTQKYLCNAAEGHRMMAMSYTCRAKQLKPLEVQEFAHHLIKSN--LQIEPFNLALWMVWNGT--------PAKDSLSTSIPKEQEVLQLLVKAGAHVSNEDDHASCIVQQALEREDSIRTLLDNGASVNQTDSNGRTLLANAAYSGNL---------EVVNLLISRRANMELVDSHGQTALTLAARQGHTKVVNCLIGCDANINHTDHDGWTALRSAAWGGHSEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHGAVVSLLIDRGAEVDHCDKDCMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMASFEGHRQVCDALIEQGSRSTEVDNDGRIPLVLSAQEGHYDCVHILLEN-KSCIDQRGYDGRNALRVAALEGHRDIVELLLSHEADIDFKDADGRPTLYILALENQLAMAEYFLE-----NGANVEASDMEGRTALHVSCWQGHVEMVRLLINYHADVNSCDNEKRSALQSAAWQGHIKIVQTLIDNGTVVDHTCNQGATALGIAAQEGHIEVVQILLEHSADPNHADQFGRTAMRVAAKGGHTAIIKLLEKYGA 812 HSP 2 Score: 250.366 bits (638), Expect = 8.912e-68 Identity = 172/523 (32.89%), Postives = 279/523 (53.35%), Query Frame = 2 Query: 1796 LLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAF-----SGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDD---DGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 LL +GA+ D +G + L A ++G +EVV LL+S++ + + + G+TAL AA G T +V L+ +NIN D +G T L +A + +V LL GA +D D D R+A+ AA + DI+ LL++ +N DNEG L+ AAY G + + + LL++ A++ D+ R+ L AA G+ VV LL+ GA + DK + L ++A +G+ ++ LL G D H DN G TPL A+ G VN LL GA + ID+ GR L ++ +G +++ L+D + N + G T L +A + + L+ +G+ +T DN+GR PL +S + YDC +LL+ N +C+D DGR A+ +A+ +G +I++ L+ A ID KD +GR L++ A + + + ++ G N++ + +G TAL ++ +GH+E+ LLIN+ A+V D+ R+ + A HIKI L +G +VD Sbjct: 241 LLDNGASVNQTDSNGRTLLANAAYSGNLEVVNLLISRRANMELVDSHGQTALTLAARQGHTKVVNCLIGCDANINHTDHDGWTALRSAAWGGHSEVVSALLYAGAKVDCADADSRTALRAAAW-----GGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHGAVVSLLIDRGAEVDHCDKDCMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE-NHRDDAGWTPLHMASFEGHRQVCDALIEQGSRSTEVDNDGRIPLVLSAQEGHYDCVHILLE--------NKSCIDQRGYDGRNALRVAALEGHRDIVELLLSHEADIDFKDADGRPTLYILALENQLAMAEYFLENGANVEASDMEGRTALHVSCWQGHVEMVRLLINYHADVNSCDNEKRSALQSAAWQGHIKIVQTLIDNGTVVD 749 HSP 3 Score: 183.726 bits (465), Expect = 1.633e-46 Identity = 145/494 (29.35%), Postives = 241/494 (48.79%), Query Frame = 2 Query: 1886 VKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISA-----SQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 ++ LL + T ++GRT L AA+ G ++V LL+S +N+ DS G+T L A + +V L+ A I+H D+DG +A+ AA +S +++ LL ++ D + L AA+ G + + LL++ A+++ D R+ L+AAA+ G+ E+V LL GA ++ D G + LS++A S+G+ ++S L+ RG + H D TPL +A+ EG + V+LLL+ GA + DN+GR PL+ + G+ + V LL GA D+ GRT L I+ Q + + LL L N DD G T +H+AS++G ++ +LI+ G+R DN+GR L L A +G Y +L++ ID+ G AL +A+ EGH +I LL++ A++ D+ R + N + + ++GA V+ ++ Sbjct: 238 IRTLLDNGASVNQTDSNGRTLLANAAYSGNLEVVNLLISRRANMELVDSHGQTALTLAARQGHTKVVNCLIGCDANINHTDHDGWTALRSAAWGGHS-----EVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHGAVVSLLIDRGAEVDHCDKDCMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASV----------------------------------VNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHR-----DDAGWTPLHMASFEGHRQVCDALIEQGSRSTEVDNDGRIPLVLSAQEGHYDCVHILLENKSCIDQRGYDGRNALRVAALEGHRDIVELLLSHEADIDFKDADGRPTLYILALENQLAMAEYFLENGANVEASDM 687 HSP 4 Score: 170.629 bits (431), Expect = 1.911e-42 Identity = 126/427 (29.51%), Postives = 222/427 (51.99%), Query Frame = 2 Query: 2081 MVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVL-----NRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 +++LL+ GA++ ++D D S I AL + D I+ LL ++N D+ G +L AAY G+ + +L+ A++++VD ++ L AA G+ +VV L+ A I+ D G++ L +A G+S+++S LL G D T L A+ G + V LL+ GA+ N+ DN GR L+ + G+ +I E L+D E VN + DG T+L +A L V L+ RGA+ D + TPL ++ + D +LL+ +++ D++GRT + A+ G ++ +L+ GA +D D+EGRT L + + QG ++ + L+D G++ + G T L +AS EGH ++C+ LI G+ +D+ R P ++ + H ++L ++ + +D++ Sbjct: 206 VLQLLVKAGAHVSNED-DHASCIVQQAL------EREDSIRTLLDNGASVNQTDSNGRTLLANAAYSGNLEVVNLLISRRANMELVDSHGQTALTLAARQGHTKVVNCLIGCDANINHTDHDGWTALRSAAWGGHSEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAE-VNHEDVDGRTALSVAALCVPASKGHGAVVSLLIDRGAEVDHCDKDCMTPLLVAAYEGHVDVVDLLLEGGA-----DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMASFEGHRQVCDALIEQGSRSTEVDNDGRIPLVLSAQEGHYDCVHILLENKSCIDQR 619 HSP 5 Score: 107.457 bits (267), Expect = 5.834e-23 Identity = 88/296 (29.73%), Postives = 139/296 (46.96%), Query Frame = 2 Query: 2561 SVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQ-EGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINN------------------------------INCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIA-----SQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 S+ + E + LL+K+GA + D+H + + + E I+ L+D SVN +G T L A + E V L+SR A+ + D++G+T L ++ Q L+ NIN+ ++C D D RTA+ A+W G +I+ +L+ GA ++ DNEGRT L A+ G +I + L+D G ++ G TALS+A + +GH + +LLI+ GA V H D TP VA H+ + +LL + GA VD + Sbjct: 199 SIPKEQEVLQLLVKAGAHVSNEDDHASCIVQQALEREDSIRT---LLDNGA-SVNQTDSNGRTLLANAAYSGNLEVVNLLISRRANMELVDSHGQTALTLAARQGHTKVVNCLI--GCDANINHTDHDGWTALRSAAWGGHSEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHGAVVSLLIDRGAEVDHCDKDCMTPLLVAAYEGHVDVVDLLLEGGADVDHTD 488
BLAST of Ankyrin repeat domain 50 vs. Ensembl Zebrafish
Match: ankrd50l (ankyrin repeat domain 50-like [Source:ZFIN;Acc:ZDB-GENE-041008-117]) HSP 1 Score: 392.119 bits (1006), Expect = 5.654e-115 Identity = 222/566 (39.22%), Postives = 333/566 (58.83%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLL---------SSGANQLM--IDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS---KYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR------SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSG--AKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDF-GINIDETC-SQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 L+ +G D + + G T+L +AA+ G + +LL S A+ L+ D +GW+ALR A W G+ E V+ LL + D +DGRTALR AAW G +I+L LL G+ ++ D EGRTPL+AA Y V++LL+ GA ++ D DGR+A+ VAALC+ S++ + +++ LLL + D +GM LL+A+YEG + + ++LLE AD+D +PL+AAA G+ V +LFWGAA+ ID G + L ++A++G+ +++ LL RGLDE H+D+ G TPLH A+ EG +L + G A+ E+D GR PL+L+ QEG+ L+D ++ ++YDG ++L A L + VE L+ RGAD ++D GR L++ VL+ + D +L++ + D +GRTA+H+A+W+GD E + L+ GA + +D +GR LH AW+G +LL+ G+N+D C QGATALS+A+QEGH EI +L+ GAN H+D RTP KVA K +H I LLE +GA Sbjct: 582 LLCHGADPSLTDNQGQTALTLAAKQGHVGVLQVLLDWVQEQRSKGSAAHTLLEHADSEGWTALRSAAWGGHKEAVRRLLEAGAEVDGCDSDGRTALRAAAWGGHEEILLTLLGHGAEVDHSDREGRTPLIAAAYMGHKETVEILLDAGADLNLADGDGRTALSVAALCVPSSAGGRGHGEVVSLLLERGADPEHKDRDGMTPLLLASYEGHEEVVELLLEAGADVDESSGAHPSSITPLLAAAAMGHTRTVNRMLFWGAAVDGIDGEGRTALCLAAAKGSIEVVRALLDRGLDENHKDDLGWTPLHAAACEGHKSVCAILTERGSMARVGELDVEGRSPLILAAQEGHCSTVRLLLDR-KSPIDHRAYDGHSALSAAALQGHRDIVELLMRRGADTDVRDAEGRPLLYLLVLEGRLDMATLLIEKGGV----PLESKDAEGRTALHVAAWRGDLEGTELLLKYGADPNARDLDGRPPLHSVAWRGHTAAGRLLLRAKGLNVDLACKQQGATALSVAAQEGHSEIVVMLLEKGANPDHVDRYGRTPVKVAGKQSHFTIVRLLESYGA 1142 HSP 2 Score: 244.973 bits (624), Expect = 1.368e-65 Identity = 133/397 (33.50%), Postives = 219/397 (55.16%), Query Frame = 2 Query: 188 KSTICRLLTTELTIDCFKTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLS-DYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASA 1375 K+ +C L + C K L S LA H+C D S+ + +F+ + + L +S G Y + I+S+ + + + PD FK +L PLLS PP +++I++DS+D + +GE S + T S +I++LL H FP W+ LVC+ R++N+ + + F GFRK LDDL K +RD+Q YIL R+D+D L++ + ET E+LNLLHIKS G ++LE V+DG+ +G + ++ I+ IPG L GLYLW+ + LF + F+ ++ + NI+L+S + L+ +++Y + D + + + + V + H+S EWL DVK CT K+ C + DGH+++A+ + +S L+ + A HL+ S Sbjct: 68 KTALCTELVWPQSETC-KAAGLASRCLAWHYCQREDAGSVEVWRFVLALVEQLKESPLLGPNYVKVISSASVATVLEPLHCQRAPDETFKRAVLEPLLSLTPPAHSVFIVVDSVDSGCCGGNGVGEG-SISGSAGTP------SSSIAELLLKHIQLFPPWILLVCSARRQNKAVCKMFSGFRKLCLDDLRKPATVRDVQQYILRRLDQDGALRRQLTPETAEMLNLLHIKSGGCFLFLERVMDGVANGLVGLREIRDIPGTLNGLYLWLCQRLFPR-RLFVHIRPLLNILLASQQPLTAEDLYTIAKSRDCYLGIRDFQAQMGALASLFVDGPEGSKLLFHSSFAEWLTDVKYCTQKFLCCVKDGHLSMAMSLSLRASSLSTEETCQLAHHLLNSG 455 HSP 3 Score: 191.815 bits (486), Expect = 6.259e-49 Identity = 148/493 (30.02%), Postives = 237/493 (48.07%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWI--------GRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNAD---IDIVDRSPLMAAAFSGNFEVVRLLLFWG--AAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFG 3121 + +L+ G +++ + +G T+L AA G I LL GA D++G + L A + G+ E V++LL D + DGRTAL AA G ++V LLL G++ +D +G TPL+ A+Y+ +V+LLL GA +D ++ G + L + + + +L + ++ ID EG L +AA +GS + + LL+ D D + +PL AAA G+ V +L G A + +D G S L ++A +G+ + LL R HR G + L A+++G + V LL++ GA + D GR L L EG + +A LI+ + K +G T+L +A E E LL GAD +D +GR PLH + ++LL+ +N G TA+ +A+ +G EI+ L++ GA D D GRT + + Q + I +LL +G Sbjct: 654 EAVRRLLEAGAEVDGCDSDGRTALRAAAWGGHEEILLTLLGHGAEVDHSDREGRTPLIAAAYMGHKETVEILLDAGADLNLADGDGRTALSVAALCVPSSAGGRGHGEVVSLLLERGADPEHKDRDGMTPLLLASYEGHEEVVELLLEAGADVD--ESSGAHPSSITPLLAAAAMGHTRTVNRMLFWGAAVDGIDGEGRTALCLAAAKGSIEVVRALLDRGLDENHKDDLGWTPLHAAACEGHKSVCAILTERGSMARVGELDVEGRSPLILAAQEGHCSTVRLLLDRKSPIDHRAYDGHSALSAAALQGHRDIVELLMRRGADTDVRDAEGRPLLYLLVLEGRLDMATLLIEKGGVPLESKDAEGRTALHVAAWRGDLEGTELLLKYGADPNARDLDGRPPLHSVAWRGHTAAGRLLLR---AKGLNVDLACKQQGATALSVAAQEGHSEIVVMLLEKGANPDHVDRYGRTPVKVAGKQSHFTIVRLLESYG 1141 HSP 4 Score: 141.739 bits (356), Expect = 2.173e-33 Identity = 107/351 (30.48%), Postives = 166/351 (47.29%), Query Frame = 2 Query: 1697 LIINGLDIN---CVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGS--NINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNA----DIDIVDRSPLMAAAFSGNFEVVRLLLFWGA-----------AIHCI------------------------DKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKP 2617 L+ G D++ + + T L+ AA G T N +L GA ID +G +AL LA G IEVV+ LL + +D + + G T L AA G + +L GS + + D EGR+PL+ A + V+LLL+ + IDH+ DG SA+ AAL + DI++LL+R + ++ D EG +L + EG + +L+E D R+ L AA+ G+ E LLL +GA +H + + G + LS++A +G+S+I+ LL +G + H D +G TP+ +A + + V LL GAKP Sbjct: 799 LLEAGADVDESSGAHPSSITPLLAAAAMGHTRTVNRMLFWGAAVDGIDGEGRTALCLAAAKGSIEVVRALLDRGLDENHKDDLGWTPLHAAACEGHKSVCAILTERGSMARVGELDVEGRSPLILAAQEGHCSTVRLLLDRKSPIDHRAYDGHSALSAAAL-----QGHRDIVELLMRRGADTDVRDAEGRPLLYLLVLEGRLDMATLLIEKGGVPLESKDAEGRTALHVAAWRGDLEGTELLLKYGADPNARDLDGRPPLHSVAWRGHTAAGRLLLRAKGLNVDLACKQQGATALSVAAQEGHSEIVVMLLEKGANPDHVDRYGRTPVKVAGKQSHFTIVRLLESYGAKP 1144 HSP 5 Score: 59.6918 bits (143), Expect = 2.727e-8 Identity = 51/152 (33.55%), Postives = 73/152 (48.03%), Query Frame = 2 Query: 2918 NINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGIN-----------IDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 ++N + LD GRT + A+ G ++ L+ GA L DN+G+T L L A QG + Q+L+D+ ++ S+G TAL A+ GH E L+ GA V DS RT + A G H +I L HGA VD + Sbjct: 554 SVNRTDPLD--GRTLLAAAAHAGLVDVAALLLCHGADPSLTDNQGQTALTLAAKQGHVGVLQVLLDWVQEQRSKGSAAHTLLEHADSEGWTALRSAAWGGHKEAVRRLLEAGAEVDGCDSDGRTALRAAAWGGHEEILLTLLGHGAEVDHSD 703
BLAST of Ankyrin repeat domain 50 vs. Ensembl Zebrafish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 229.95 bits (585), Expect = 1.066e-60 Identity = 165/580 (28.45%), Postives = 280/580 (48.28%), Query Frame = 2 Query: 1601 TSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 T +S + + + S + R + + + G+DIN N+NG +L +A++ G + LL GAN K G +AL +A G EVV+ L++ + + +G T L AA D+V LL + S+ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D + R +PL A+ GN +V+LLL G+ I K G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL+ A +++ N L ++ G+ K+A+ ++D + N K+ +G T L IA + +E LL GA +G TP+H++ + + L H + N N+ G TA+H+A+ G ++++ L+ GA++D+K + +T LH+ + G +I Q L+ G + + G T L ++++EGH EI LL+ G+++ TP VA K +++ NLL + A D Sbjct: 29 TRKHSRDQKKKSDSNASYLRAARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKK-ANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVR-----GETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPD 593 HSP 2 Score: 209.149 bits (531), Expect = 4.002e-54 Identity = 158/550 (28.73%), Postives = 257/550 (46.73%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 ++ + N + L+ G I ++G T L A++G + +LL GA L K+G S L +A ++ V+LLL D ND TAL AA G + +++ +N N + G TPL A K +++LLL +GA + G + I VAA + N I+K L + + N + G L +AA G + + LL+N A +DI D++ L A+ G E+V+ LL GA + SG++ L +SA +G+ +I + LL +G G TPLH+A+ GQ E NLLL+ A P+ G PL ++ ++A L+D S + + +G T L IA E LL GA+ G +PLH++ + D +LL N+N + +G T +H+A+ + + L++ GA ID + G T LH+ G ++ L++ + G T L A+Q+GH I N+L+ +GA+ + T +A + +I + + L Sbjct: 278 KRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHEN-----IVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQG-ASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQA-----NVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTL 816 HSP 3 Score: 190.274 bits (482), Expect = 2.942e-48 Identity = 157/591 (26.57%), Postives = 272/591 (46.02%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALC-------------LNSNSKYLD---------------IIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNAD---IDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLID--VWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 +L + R++ + + L+ N + + +++G T L +AA G ++ LLL+ GA + ++ + L +A G +VKLLL + + DG T L A G +V +LL G+ I + G +PL AT V+LLL + A +D ND +A+ VAA C N N+K L+ +++LLL++ ++ + G+ + +AA+ G + + K L + A ++ + L AA +G +VVR LL GA + K + L I++ G +I+ +LL +G G TPLHL++ EG E LLL+ G+ + G PL ++ + G +++A L+ P++ G T L +A LL +GA NG TPLHI+ ++Q + LL++ N + G + +H+A+ +G +++ L+ A +++ + G T LHL A + ++L++ G ID G T L +A G++++ N L+ A TP A + H I N+L ++GA Sbjct: 206 ALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAA---GKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGA-----ECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGA 788 HSP 4 Score: 189.119 bits (479), Expect = 5.694e-48 Identity = 168/633 (26.54%), Postives = 290/633 (45.81%), Query Frame = 2 Query: 1526 INLVNINKLNA-----KKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAV-LNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 IN+ N N LNA K+ +L + + N AT + +L + + +L+ NG ++N ++NG T L +AAQ + LL + ++Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ G+ ++ TPL A+ + + MVKLLL+ G+ I+ + DG + + A S + ++++LL I G++ L +A +G L C ++LL++NA +D V L A AA G+++V ++++ A + +GF+ L I+ + +++ LL G G TP+H+A+ G V L GA PN + G L ++ + G I + L+ + V+ K+ D T+L IA L +L E V+ LL +GA +G TPLH+S + + +LL+ ++++ G T +H+A+ G E+ L+ A D G T LH+ A ++ LL+D G + G T L IA+++ LEI L+ +GA + +P +A + + + +LL Sbjct: 68 INICNQNGLNALHLASKEGHVEVVAELLKLGA---NVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGA-----RSGHEQVVEMLLDRGAPILSKTKNGLSPLHMAT-QGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAK-VDIKAKDDQTALHIASRLGKL-EIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQG-----SSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLL 684 HSP 5 Score: 161.77 bits (408), Expect = 1.645e-39 Identity = 137/496 (27.62%), Postives = 226/496 (45.56%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 A G +E V L +D + +G AL A+ G ++V LL G+N++ +G T L A+ +V+ L+ NGA ++ Q +G + +++AA +LD+++ LL N + ++ +G L +A +G + +LLEN+ + R P L AA + + LLL KSGF+ L I+A GN + + LL RG +D M R++ TPLH+AS G V LLL G+K + K+ DG T L + + VE LL RGA + NG +PLH++ +C Q+LLQH+ ++ + +D TA+H+A+ G ++ K ++D A + K G T LH+ + ++ +LL+ G ++ G T + +A+ GH I L + GA+ + T +A + I + L ++GA VD K Sbjct: 49 AARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAA-----QENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDI--TPLHVASKRGNGNMVKLLLDRGSK----------------------------------IEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAP-----VDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIK 496 HSP 6 Score: 157.147 bits (396), Expect = 4.965e-38 Identity = 132/468 (28.21%), Postives = 214/468 (45.73%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDV 3019 + TN Y +L + Y ++ + N NG T L +A + + LLL GA+ + + G + + +A + G+ +VK L P+ T G TAL AA G+ D+V LL +G+ ++ + + +T L A+ +V+ LL GA + G + L L++ + +I LLL +++ +G L +AA G + +LL+ A D +S PL AA N V LLL GA+ H K+G++ L I+A + +I + LL G + G +PLHLA+ EG + V+LLL A N + +G PL L+ Q+ + E L++ E ++ ++ G T L +A + FLL A + NG TPLH + Q +LLQ+ + N +N G TA+ IA G ++ +L V Sbjct: 363 DVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYT-----PLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAE-IDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLN-----GNTALSIARRLGYISVVDTLRGV 819 HSP 7 Score: 150.599 bits (379), Expect = 4.441e-36 Identity = 121/419 (28.88%), Postives = 189/419 (45.11%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRT 2845 N + QL +G N N G T+L +AA+ G + LL +GA + KD +AL +A G +E+V+ LL + P+ G T L +A G +I LLL GS+++ +G TPL A + LLL A D G + + VAA L + + L+I LL Y N + +G++ L +AA EGS L +LL A++++ ++ +PL AA V +LL GA I KSG++ L ++ GN ++ + LL + G TPLH A+ +G +N+LL+ GA PNE+ +G L ++ + GYI + + L V E N + + KI V PE + L D ++D+ +T Sbjct: 448 NIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTLRGVTDE--NLTATPITEKHKINV----PETMNEFLDMSDDEAVKDHEAQT 860
BLAST of Ankyrin repeat domain 50 vs. Ensembl Zebrafish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 229.95 bits (585), Expect = 1.066e-60 Identity = 165/580 (28.45%), Postives = 280/580 (48.28%), Query Frame = 2 Query: 1601 TSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 T +S + + + S + R + + + G+DIN N+NG +L +A++ G + LL GAN K G +AL +A G EVV+ L++ + + +G T L AA D+V LL + S+ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D + R +PL A+ GN +V+LLL G+ I K G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL+ A +++ N L ++ G+ K+A+ ++D + N K+ +G T L IA + +E LL GA +G TP+H++ + + L H + N N+ G TA+H+A+ G ++++ L+ GA++D+K + +T LH+ + G +I Q L+ G + + G T L ++++EGH EI LL+ G+++ TP VA K +++ NLL + A D Sbjct: 29 TRKHSRDQKKKSDSNASYLRAARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKK-ANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVR-----GETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPD 593 HSP 2 Score: 209.149 bits (531), Expect = 4.002e-54 Identity = 158/550 (28.73%), Postives = 257/550 (46.73%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 ++ + N + L+ G I ++G T L A++G + +LL GA L K+G S L +A ++ V+LLL D ND TAL AA G + +++ +N N + G TPL A K +++LLL +GA + G + I VAA + N I+K L + + N + G L +AA G + + LL+N A +DI D++ L A+ G E+V+ LL GA + SG++ L +SA +G+ +I + LL +G G TPLH+A+ GQ E NLLL+ A P+ G PL ++ ++A L+D S + + +G T L IA E LL GA+ G +PLH++ + D +LL N+N + +G T +H+A+ + + L++ GA ID + G T LH+ G ++ L++ + G T L A+Q+GH I N+L+ +GA+ + T +A + +I + + L Sbjct: 278 KRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHEN-----IVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQG-ASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQA-----NVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTL 816 HSP 3 Score: 190.274 bits (482), Expect = 2.942e-48 Identity = 157/591 (26.57%), Postives = 272/591 (46.02%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALC-------------LNSNSKYLD---------------IIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNAD---IDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLID--VWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 +L + R++ + + L+ N + + +++G T L +AA G ++ LLL+ GA + ++ + L +A G +VKLLL + + DG T L A G +V +LL G+ I + G +PL AT V+LLL + A +D ND +A+ VAA C N N+K L+ +++LLL++ ++ + G+ + +AA+ G + + K L + A ++ + L AA +G +VVR LL GA + K + L I++ G +I+ +LL +G G TPLHL++ EG E LLL+ G+ + G PL ++ + G +++A L+ P++ G T L +A LL +GA NG TPLHI+ ++Q + LL++ N + G + +H+A+ +G +++ L+ A +++ + G T LHL A + ++L++ G ID G T L +A G++++ N L+ A TP A + H I N+L ++GA Sbjct: 206 ALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAA---GKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGA-----ECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGA 788 HSP 4 Score: 189.119 bits (479), Expect = 5.694e-48 Identity = 168/633 (26.54%), Postives = 290/633 (45.81%), Query Frame = 2 Query: 1526 INLVNINKLNA-----KKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAV-LNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 IN+ N N LNA K+ +L + + N AT + +L + + +L+ NG ++N ++NG T L +AAQ + LL + ++Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ G+ ++ TPL A+ + + MVKLLL+ G+ I+ + DG + + A S + ++++LL I G++ L +A +G L C ++LL++NA +D V L A AA G+++V ++++ A + +GF+ L I+ + +++ LL G G TP+H+A+ G V L GA PN + G L ++ + G I + L+ + V+ K+ D T+L IA L +L E V+ LL +GA +G TPLH+S + + +LL+ ++++ G T +H+A+ G E+ L+ A D G T LH+ A ++ LL+D G + G T L IA+++ LEI L+ +GA + +P +A + + + +LL Sbjct: 68 INICNQNGLNALHLASKEGHVEVVAELLKLGA---NVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGA-----RSGHEQVVEMLLDRGAPILSKTKNGLSPLHMAT-QGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAK-VDIKAKDDQTALHIASRLGKL-EIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQG-----SSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLL 684 HSP 5 Score: 161.77 bits (408), Expect = 1.645e-39 Identity = 137/496 (27.62%), Postives = 226/496 (45.56%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 A G +E V L +D + +G AL A+ G ++V LL G+N++ +G T L A+ +V+ L+ NGA ++ Q +G + +++AA +LD+++ LL N + ++ +G L +A +G + +LLEN+ + R P L AA + + LLL KSGF+ L I+A GN + + LL RG +D M R++ TPLH+AS G V LLL G+K + K+ DG T L + + VE LL RGA + NG +PLH++ +C Q+LLQH+ ++ + +D TA+H+A+ G ++ K ++D A + K G T LH+ + ++ +LL+ G ++ G T + +A+ GH I L + GA+ + T +A + I + L ++GA VD K Sbjct: 49 AARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAA-----QENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDI--TPLHVASKRGNGNMVKLLLDRGSK----------------------------------IEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAP-----VDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIK 496 HSP 6 Score: 157.147 bits (396), Expect = 4.965e-38 Identity = 132/468 (28.21%), Postives = 214/468 (45.73%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDV 3019 + TN Y +L + Y ++ + N NG T L +A + + LLL GA+ + + G + + +A + G+ +VK L P+ T G TAL AA G+ D+V LL +G+ ++ + + +T L A+ +V+ LL GA + G + L L++ + +I LLL +++ +G L +AA G + +LL+ A D +S PL AA N V LLL GA+ H K+G++ L I+A + +I + LL G + G +PLHLA+ EG + V+LLL A N + +G PL L+ Q+ + E L++ E ++ ++ G T L +A + FLL A + NG TPLH + Q +LLQ+ + N +N G TA+ IA G ++ +L V Sbjct: 363 DVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYT-----PLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAE-IDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLN-----GNTALSIARRLGYISVVDTLRGV 819 HSP 7 Score: 150.599 bits (379), Expect = 4.441e-36 Identity = 121/419 (28.88%), Postives = 189/419 (45.11%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRT 2845 N + QL +G N N G T+L +AA+ G + LL +GA + KD +AL +A G +E+V+ LL + P+ G T L +A G +I LLL GS+++ +G TPL A + LLL A D G + + VAA L + + L+I LL Y N + +G++ L +AA EGS L +LL A++++ ++ +PL AA V +LL GA I KSG++ L ++ GN ++ + LL + G TPLH A+ +G +N+LL+ GA PNE+ +G L ++ + GYI + + L V E N + + KI V PE + L D ++D+ +T Sbjct: 448 NIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTLRGVTDE--NLTATPITEKHKINV----PETMNEFLDMSDDEAVKDHEAQT 860
BLAST of Ankyrin repeat domain 50 vs. Ensembl Zebrafish
Match: BX469921.1 (ankyrin 3a [Source:NCBI gene;Acc:103909035]) HSP 1 Score: 229.95 bits (585), Expect = 1.079e-60 Identity = 163/564 (28.90%), Postives = 274/564 (48.58%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S + R + + + G+DIN N+NG +L +A++ G + LL GAN K G +AL +A G EVV+ L++ + + +G T L AA D+V LL + S+ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D + R +PL A+ GN +V+LLL G+ I K G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL+ A +++ N L ++ G+ K+A+ ++D + N K+ +G T L IA + +E LL GA +G TP+H++ + + L H + N N+ G TA+H+A+ G ++++ L+ GA++D+K + +T LH+ + G +I Q L+ G + + G T L ++++EGH EI LL+ G+++ TP VA K +++ NLL + A D Sbjct: 45 SYLRAARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKK-ANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVR-----GETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPD 593 HSP 2 Score: 196.052 bits (497), Expect = 4.560e-50 Identity = 154/555 (27.75%), Postives = 255/555 (45.95%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATA-----LSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 ++ + N + L+ G I ++G T L A++G + +LL GA L K+G S L +A ++ V+LLL D ND TAL AA G + +++ +N N + G TPL A K +++LLL +GA + G + I VAA + N I+K L + + N + G L +AA G + + LL+N A +DI D++ L A+ G E+V+ LL GA + SG++ L +SA +G+ +I + LL +G G TPLH+A+ GQ E NLLL+ A P+ G PL ++ ++A L+D S + + +G T L IA E LL GA+ G +PLH++ + D +LL N+N + +G T +H+A+ + + L++ GA ID + G T LH+ G ++ L++ + + ++Q+GH I N+L+ +GA+ + T +A + +I + + L Sbjct: 278 KRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHEN-----IVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQG-ASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQA-----NVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKVIVNGYFDMLIPFSAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTL 821 HSP 3 Score: 189.889 bits (481), Expect = 3.950e-48 Identity = 168/633 (26.54%), Postives = 290/633 (45.81%), Query Frame = 2 Query: 1526 INLVNINKLNA-----KKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAV-LNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 IN+ N N LNA K+ +L + + N AT + +L + + +L+ NG ++N ++NG T L +AAQ + LL + ++Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ G+ ++ TPL A+ + + MVKLLL+ G+ I+ + DG + + A S + ++++LL I G++ L +A +G L C ++LL++NA +D V L A AA G+++V ++++ A + +GF+ L I+ + +++ LL G G TP+H+A+ G V L GA PN + G L ++ + G I + L+ + V+ K+ D T+L IA L +L E V+ LL +GA +G TPLH+S + + +LL+ ++++ G T +H+A+ G E+ L+ A D G T LH+ A ++ LL+D G + G T L IA+++ LEI L+ +GA + +P +A + + + +LL Sbjct: 68 INICNQNGLNALHLASKEGHVEVVAELLKLGA---NVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGA-----RSGHEQVVEMLLDRGAPILSKTKNGLSPLHMAT-QGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAK-VDIKAKDDQTALHIASRLGKL-EIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQG-----SSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLL 684 HSP 4 Score: 187.578 bits (475), Expect = 1.710e-47 Identity = 162/562 (28.83%), Postives = 267/562 (47.51%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLL----QHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 +L + R++ + + L+ N + + +++G T L +AA G ++ LLL+ GA + ++ + L +A G +VKLLL + + DG T L A G +V +LL G+ I + G +PL AT V+LLL + A +D ND +A+ VAA C + + K+++ N N G L IA + + ++LL++ A + V S P+ AAF G+ +V+ L GA+ + + G + L ++A G ++ LL G +D +D+ T LH+AS G+ E V LL+ GA PN G PL LS +EG+ +IA L++ S++ + G T L +A E LL + A +G TPLH++ + YD +V L Q + H+ +G T +HIA+ K EI +L++ GA + +G + LHL A +G + LL+ N++ G T L +A+Q+ + +L+N GA + TP VA ++K+ N L Sbjct: 206 ALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHC-----GHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDD--QTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQG-SSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVA---AHYDNQRVALLLLDQGASPHSPAK------NGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFL 750 HSP 5 Score: 149.828 bits (377), Expect = 6.926e-36 Identity = 137/531 (25.80%), Postives = 219/531 (41.24%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLL 3208 + TN Y +L + Y ++ + N NG T L +A + + LLL GA+ + + G + + +A + G+ +VK L P+ T G TAL AA G+ D+V L L NGA +D + D ++A+ +A S L+I++ LL+ N G L ++A EG + + +LLE + + + +PL AA G EV LLL AA KSG + L ++A N ++ LL +G G TPLH+A+ + Q E LL+ GA+ N + G PL L+ QEG + + L+ +VN + +G T L +A + E LL+ GA+ Q +G TPLH++ LL++ N K+ + V D+ + A QG I +L+ +G + +E G TALSIA + G++ + + L Sbjct: 363 DVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYL---------------------------------LQNGAKVDIKAKDDQTALHIA-----SRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLL-TKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPN--------------------------AKTKVIVNGYFDML-------IPFSAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTL 821 HSP 6 Score: 148.673 bits (374), Expect = 1.988e-35 Identity = 134/498 (26.91%), Postives = 212/498 (42.57%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 A G +E V L +D + +G AL A+ G ++V LL G+N++ +G T L A+ +V+ L+ NGA ++ Q +G + +++AA +LD+++ LL N + ++ +G L +A +G + +LLEN+ + R P L AA + + LLL KSGF+ L I+A GN + + LL RG +D M R++ TPLH+AS G V LLL G+K + K+ DG T L + + VE LL RGA + NG +PLH++ +C Q+LLQH+ A +D N+ T LH+ A G Y++ ++++D N + G T L IA ++ +++ LL+ GA++ + TP VA H I L HGA + NV Sbjct: 49 AARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAA-----QENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDI--TPLHVASKRGNGNMVKLLLDRGSK----------------------------------IEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHN--------------------------------------APVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNV 465 HSP 7 Score: 130.568 bits (327), Expect = 5.640e-30 Identity = 115/424 (27.12%), Postives = 187/424 (44.10%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHR-----DNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRT 2845 N + QL +G N N G T+L +AA+ G + LL +GA + KD +AL +A G +E+V+ LL + P+ G T L +A G +I LLL GS+++ +G TPL A + LLL A D G + + VAA L + + L+I LL Y N + +G++ L +AA EGS L +LL A++++ ++ +PL AA V +LL GA I KSG++ L ++ GN ++ + LL + + + + ++ +G +N+LL+ GA PNE+ +G L ++ + GYI + + L V E N + + KI V PE + L D ++D+ +T Sbjct: 448 NIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKVIVNGYFDMLIPFSAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTLRGVTDE--NLTATPITEKHKINV----PETMNEFLDMSDDEAVKDHEAQT 865
BLAST of Ankyrin repeat domain 50 vs. Ensembl Xenopus
Match: gart (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:Xenbase;Acc:XB-GENE-993017]) HSP 1 Score: 700.279 bits (1806), Expect = 0.000e+0 Identity = 394/1036 (38.03%), Postives = 598/1036 (57.72%), Query Frame = 2 Query: 266 LASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDE--NLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIE--VKGILPCE--------KFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALV 3328 LA HFC A D D++ + FI + + + + +N + +L P AFK +LLPLL+ P +++++++DS+DE N++ GE H+ S I+DLL+ HH FFP WL L+C+ RK++ + + F GFRK LDDL K+Y+++D+Q YIL+R+D+++ L+Q + ET E+LN LHIKS+G +YLE VLDG+++ ++ ++ I+ IPG L GLYLW+ + LF Q F V+ I N++L++ K L+ E++ A+ +++ + + L + LV+ N H S EWLLDVK CT KY C+ +GH LA+ + +L P++++ FA HLI S + A+W++ + ++ + ++P E K G+ D D I+ +++ + + ++ N + ++ A YS +L + ++ L+ G D+ + NG T+L +AA+ G + N L+ GAN D DGW+ALR A W G+ EVV LL D D RTALR AAW G DIVL LL G+ +NK D+EGRT L+AA Y +V+ LL +GA I+H+D DGR+A+ VAALC+ ++ + ++ LL+ ++ D +GM LL+AAYEG + +LLE AD+D D R+PL+AAA G+ VV LLFWGAA+ ID G +VLSI+++QGN +++ LL RGLDE HRD+ G TPLH+A+ EG L++ GA+ NEIDN GRIPL+L+ QEG+ + L++ +V+ K YDG ++L++A L + VE LLS GAD +D +GR L+I L++Q + L+ N N+ D DGRTA+H++ W+G E+++SLI A ++ DNE R+ L AWQG ++ QLLI+ G +D TC+QGATAL IA+QEGH ++ L+ GA+ H D RT +VA K H +I LLEK+GA + Sbjct: 96 LAYHFCRAQDSDTMCVGSFIRSLVDQICQGGLM-PGFEDKLNDPSVQSLLQPGECERNPSEAFKRCVLLPLLAIKAPAQSLFMVVDSVDEGCNIVE---GE-----------HRPSGLSGTIADLLATHHEFFPPWLLLICSARKQSRTVTKMFTGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAEMLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQ-FAKVQPILNVILAACKPLTTIELFNAVWTKNMSLTMEDFQRKLDVLSKVLVEGLGNTKILFHYSFAEWLLDVKHCTQKYLCNAAEGHRMLAMSYTCRAKELTPIEVQEFALHLIHSN--LQLTNSELALWMILNGTCVKDSLCTLIPKEQEVLQLLVKAGAHVDSEDDRTCCIVRQALEREDSIRTLLDNGASV------NQCDSNGRTLLANTAYSGNL---------DVVNLLVSRGSDLEIEDANGQTALTLAARQGHVKVVNCLIGCGANINHCDHDGWTALRSAAWGGHTEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLGHGAEINHEDVDGRTALSVAALCVPASKGHASVVSLLIEQGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHAAVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPLILAAQEGHYDCVQILLEN-KSAVDQKGYDGRSALRVAALEGHRDIVELLLSNGADLNAKDADGRPTLYILALENQLSMAEYFLE-----NGANVEASDTDGRTALHVSCWQGHLEMVQSLISYKADVNASDNEKRSSLQSAAWQGHVKVVQLLIEHGTLVDNTCNQGATALCIAAQEGHTDVVQFLLENGADPNHADQFGRTAMRVAAKNGHSEIIKLLEKYGASI 1092 HSP 2 Score: 249.98 bits (637), Expect = 6.001e-67 Identity = 171/520 (32.88%), Postives = 277/520 (53.27%), Query Frame = 2 Query: 1796 LLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAF-----SGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 LL +GA+ D +G + L ++G ++VV LL+S+ D + +G+TAL AA G +V L+ G+NIN D +G T L +A + +V LL GA +D D D R+A+ AA + DI+ LL++ +N DNEG L+ AAY G + + + LL + A+I D+ R+ L AA G+ VV LL+ GA + DK G + L ++A +G+ ++ LL G D H DN G TPL A+ G VN LL GA + ID+ GR L ++ +G +++ L+D + N + G T L +A E L+ +GA DN+GR PL ++ + YDC Q+LL+ N + ++ DGR+A+ +A+ +G +I++ L+ GA ++ KD +GR L++ A + + + ++ G N++ + + G TAL ++ +GHLE+ LI++ A+V D+ R+ + A H+K+ LL +HG LVD Sbjct: 519 LLDNGASVNQCDSNGRTLLANTAYSGNLDVVNLLVSRGSDLEIEDANGQTALTLAARQGHVKVVNCLIGCGANINHCDHDGWTALRSAAWGGHTEVVSALLYAGAKVDCADADSRTALRAAAW-----GGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLGHGAEINHEDVDGRTALSVAALCVPASKGHASVVSLLIEQGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHAAVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE-NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPLILAAQEGHYDCVQILLE-----NKSAVDQKGYDGRSALRVAALEGHRDIVELLLSNGADLNAKDADGRPTLYILALENQLSMAEYFLENGANVEASDTDGRTALHVSCWQGHLEMVQSLISYKADVNASDNEKRSSLQSAAWQGHVKVVQLLIEHGTLVD 1027 HSP 3 Score: 168.703 bits (426), Expect = 1.282e-41 Identity = 128/427 (29.98%), Postives = 217/427 (50.82%), Query Frame = 2 Query: 2081 MVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVL-----NRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 +++LL+ GA++D +D D I AL + D I+ LL ++N D+ G +L AY G+ + +L+ +D++I D ++ L AA G+ +VV L+ GA I+ D G++ L +A G+++++S LL G D T L A+ G + V LL+ GA+ N+ DN GR L+ + G+ +I E L+ E +N + DG T+L +A L V L+ +GA+ D +G TPL ++ + D +LL+ +++ D++GRT + A+ G ++ +L+ GA +D D+EGRT L + + QG ++ + L+D G++ + G T L +A+ EGH IC LI GA ID+ R P +A + H +L ++ + VD+K Sbjct: 484 VLQLLVKAGAHVDSED-DRTCCIVRQAL------EREDSIRTLLDNGASVNQCDSNGRTLLANTAYSGNLDVVNLLVSRGSDLEIEDANGQTALTLAARQGHVKVVNCLIGCGANINHCDHDGWTALRSAAWGGHTEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLGHGAE-INHEDVDGRTALSVAALCVPASKGHASVVSLLIEQGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGA-----DVDHTDNNGRTPLLAAASMGHAAVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPLILAAQEGHYDCVQILLENKSAVDQK 897 HSP 4 Score: 148.288 bits (373), Expect = 2.664e-35 Identity = 101/303 (33.33%), Postives = 160/303 (52.81%), Query Frame = 2 Query: 1670 QNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVE 2569 Q + + L+ GLD N ++ G T L +AA G IC L+ GA ID DG L LA G+ + V++LL K D G DGR+ALR AA G DIV LLLS+G+++N +D++GR L + M + L NGA ++ D DGR+A+ V+ C +L++++ L+ Y ++N DNE + L AA++G + ++L+E+ +D + L AA G+ +VV+ LL GA + D+ G + + ++A G+S+I+ L G GC P + ++E Sbjct: 812 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPLILAAQEGHYDCVQILLENKSAVDQKGYDGRSALRVAALEGHRDIVELLLSNGADLNAKDADGRPTLYILALENQLSMAEYFLENGANVEASDTDGRTALHVS--CWQG---HLEMVQSLISYKADVNASDNEKRSSLQSAAWQGHVKVVQLLIEHGTLVDNTCNQGATALCIAAQEGHTDVVQFLLENGADPNHADQFGRTAMRVAAKNGHSEIIKLLEKYGAS----IPSGCNPSPVHTME 1105 HSP 5 Score: 76.6406 bits (187), Expect = 2.290e-13 Identity = 56/187 (29.95%), Postives = 94/187 (50.27%), Query Frame = 2 Query: 2780 EFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 E ++ L+ GA +D+ RT + + D + LL N ++N D +GRT + ++ G+ +++ L+ G+ ++++D G+T L L A QG ++ LI G NI+ G TAL A+ GH E+ + L+ GA V D+ RT + A G H I L +HGA V++ + Sbjct: 483 EVLQLLVKAGAHVDSEDD--RTCCIVRQALEREDSIRTLLD-----NGASVNQCDSNGRTLLANTAYSGNLDVVNLLVSRGSDLEIEDANGQTALTLAARQGHVKVVNCLIGCGANINHCDHDGWTALRSAAWGGHTEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKAD 662 HSP 6 Score: 74.3294 bits (181), Expect = 1.378e-12 Identity = 55/186 (29.57%), Postives = 89/186 (47.85%), Query Frame = 2 Query: 2786 VEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 + LL GA D+NGRT L + D +L+ +++ D +G+TA+ +A+ +G +++ LI GA I+ D++G T L AW G ++ L+ G +D + TAL A+ GH +I L+ GA V D+ RT A H +I L HGA ++ ++V Sbjct: 516 IRTLLDNGASVNQCDSNGRTLLANTAYSGNLDVVNLLVSRG-----SDLEIEDANGQTALTLAARQGHVKVVNCLIGCGANINHCDHDGWTALRSAAWGGHTEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLGHGAEINHEDV 696
BLAST of Ankyrin repeat domain 50 vs. Ensembl Xenopus
Match: tpm4 (tropomyosin 4 [Source:Xenbase;Acc:XB-GENE-6077097]) HSP 1 Score: 226.098 bits (575), Expect = 2.965e-59 Identity = 163/546 (29.85%), Postives = 270/546 (49.45%), Query Frame = 2 Query: 1706 NGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIA-VLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 NG+DIN N+NG +L +A++ G I + L+ GA+ K G +AL +A G EVV++L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL G+ I + G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D + N K+ +G T L IA NRL + +E LL GA +G TP+H++ + L H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G D + G T L ++S+EGH ++ ++L+ GA+ + TP VA K I++ LL + A D Sbjct: 46 NGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRL-KVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVR-----GETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPD 575 HSP 2 Score: 206.068 bits (523), Expect = 5.465e-53 Identity = 157/551 (28.49%), Postives = 255/551 (46.28%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL GA L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL +N N + G TPL A K +++LLL +GA I G + I VAA +++I+ L + + N + G L +AA G + + LL+N A ++ D++PL +A G ++V+ LL GA SG++ L +S+ +G+ + S LL G G TPLH+A+ G+ E V LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G P+H++ + D +LL S N+N + G T +H+A+ + + + L + GA ID T LH+ + G ++ L+ G ++ G T L A+Q+GH I N+L+ GA+ + T +A + +I + + L+ Sbjct: 260 KRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKG-ASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSA-----NVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLK 799 HSP 3 Score: 203.371 bits (516), Expect = 3.991e-52 Identity = 167/637 (26.22%), Postives = 285/637 (44.74%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLID--VWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQ----------------HSLTHNINNINCL------------DDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ G+ ++ TPL A+ + + MVKLLL+ G+ ID + DG + + A L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A+ + + +PL A +V+ LLL GA+I + +SG + + ++A G+ I+S+L G + G T LH+A+ GQ E V LL++GA+ + PL +S + G I ++L+ +P++ Y T L ++ + LL GA I G TPLH++ + + ++LLQ H H N L +G T +HIA+ K +I +L++ GA + +G +HL A +G + LL+ N++ + G T L +A+QE + + +L N GA + TP VA +IK+ L +HG+ V+ K Sbjct: 109 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGY---TPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAK 742 HSP 4 Score: 178.718 bits (452), Expect = 1.300e-44 Identity = 138/470 (29.36%), Postives = 215/470 (45.74%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEF-----VEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ + N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L P+ T G TAL AA G++++V LL +G+ + + + +TPL + +V+ LL GAY D G + L L+S + D+ +LL + + ++ +G L +AA G + K+LL+ NA D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G P+HLA+ EG + V+LLL A N + G PL L+ QE + +AE L + DG+T + L+ + V FLL G+ + NG TPLH + Q VLLQH + N +N G TA+ IA G ++ +L Sbjct: 345 DVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYT-----PLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLAN------QGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVN-----GNTALAIARRLGYISVVDTL 798 HSP 5 Score: 145.976 bits (367), Expect = 1.799e-34 Identity = 131/498 (26.31%), Postives = 213/498 (42.77%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 A +G +E L +D + +G AL A+ G +IV L+ G++++ +G T L A+ +V++L+ NGA ++ Q +G + +++AA +L+++K LL + +L +G L +A +G + +LLEN+ + R P L AA + + LLL KSGF+ L I+A GN + + LL RG +D R++ TPLH+AS G V LLL G+K ++ K+ DG T L + + V LL RGA + NG +PLH++ +C Q+LLQH++ +D N+ T LH+ A G Y++ ++L+D N + G T L IA ++ L++ LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 31 AARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAA-----QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDI--TPLHVASKRGNANMVKLLLDRGSK----------------------------------IDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVP--------------------------------------VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNV 447 HSP 6 Score: 135.576 bits (340), Expect = 2.984e-31 Identity = 116/421 (27.55%), Postives = 202/421 (47.98%), Query Frame = 2 Query: 2081 MVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIP-LMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQIC-QLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALV 3328 M + A H+ G+ + A+ + S L+ L+ +IN+ + G+N L +A+ EG + L++ AD+D + + L A+ +G EVVR+L+ GA ++ ++GF+ L ++A + + +++ LL G + G TPL +A +G + V+LLL+ N+ R+P L ++ ++ K A L+ + + +S G T L IA LL+RGA N TPLH++ + + ++LL + I+ DG T +H + G +++ L+D GA I K G + LH+ A QG + C QLL+ + +D+ + TAL +A+ GH ++ +L++ AN TP +A K N +K+ LL KHGA + Sbjct: 1 MSEETKEKAAKPAHRKRKGKKSDTNASYLRAARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQ-NDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRG-----SKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHM-ATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASI 409
BLAST of Ankyrin repeat domain 50 vs. Ensembl Xenopus
Match: tpm4 (tropomyosin 4 [Source:Xenbase;Acc:XB-GENE-6077097]) HSP 1 Score: 226.098 bits (575), Expect = 3.068e-59 Identity = 163/546 (29.85%), Postives = 270/546 (49.45%), Query Frame = 2 Query: 1706 NGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIA-VLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 NG+DIN N+NG +L +A++ G I + L+ GA+ K G +AL +A G EVV++L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL G+ I + G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D + N K+ +G T L IA NRL + +E LL GA +G TP+H++ + L H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G D + G T L ++S+EGH ++ ++L+ GA+ + TP VA K I++ LL + A D Sbjct: 46 NGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRL-KVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVR-----GETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPD 575 HSP 2 Score: 205.682 bits (522), Expect = 7.620e-53 Identity = 157/551 (28.49%), Postives = 255/551 (46.28%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL GA L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL +N N + G TPL A K +++LLL +GA I G + I VAA +++I+ L + + N + G L +AA G + + LL+N A ++ D++PL +A G ++V+ LL GA SG++ L +S+ +G+ + S LL G G TPLH+A+ G+ E V LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G P+H++ + D +LL S N+N + G T +H+A+ + + + L + GA ID T LH+ + G ++ L+ G ++ G T L A+Q+GH I N+L+ GA+ + T +A + +I + + L+ Sbjct: 260 KRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKG-ASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSA-----NVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLK 799 HSP 3 Score: 202.986 bits (515), Expect = 5.236e-52 Identity = 167/637 (26.22%), Postives = 285/637 (44.74%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLID--VWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQ----------------HSLTHNINNINCL------------DDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ G+ ++ TPL A+ + + MVKLLL+ G+ ID + DG + + A L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A+ + + +PL A +V+ LLL GA+I + +SG + + ++A G+ I+S+L G + G T LH+A+ GQ E V LL++GA+ + PL +S + G I ++L+ +P++ Y T L ++ + LL GA I G TPLH++ + + ++LLQ H H N L +G T +HIA+ K +I +L++ GA + +G +HL A +G + LL+ N++ + G T L +A+QE + + +L N GA + TP VA +IK+ L +HG+ V+ K Sbjct: 109 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGY---TPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAK 742 HSP 4 Score: 178.718 bits (452), Expect = 1.639e-44 Identity = 138/470 (29.36%), Postives = 215/470 (45.74%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEF-----VEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ + N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L P+ T G TAL AA G++++V LL +G+ + + + +TPL + +V+ LL GAY D G + L L+S + D+ +LL + + ++ +G L +AA G + K+LL+ NA D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G P+HLA+ EG + V+LLL A N + G PL L+ QE + +AE L + DG+T + L+ + V FLL G+ + NG TPLH + Q VLLQH + N +N G TA+ IA G ++ +L Sbjct: 345 DVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYT-----PLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLAN------QGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVN-----GNTALAIARRLGYISVVDTL 798 HSP 5 Score: 145.591 bits (366), Expect = 2.313e-34 Identity = 131/498 (26.31%), Postives = 213/498 (42.77%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 A +G +E L +D + +G AL A+ G +IV L+ G++++ +G T L A+ +V++L+ NGA ++ Q +G + +++AA +L+++K LL + +L +G L +A +G + +LLEN+ + R P L AA + + LLL KSGF+ L I+A GN + + LL RG +D R++ TPLH+AS G V LLL G+K ++ K+ DG T L + + V LL RGA + NG +PLH++ +C Q+LLQH++ +D N+ T LH+ A G Y++ ++L+D N + G T L IA ++ L++ LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 31 AARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAA-----QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDI--TPLHVASKRGNANMVKLLLDRGSK----------------------------------IDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVP--------------------------------------VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNV 447 HSP 6 Score: 145.206 bits (365), Expect = 3.390e-34 Identity = 107/377 (28.38%), Postives = 173/377 (45.89%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESV 2719 N +SQL +G N N G T+L +AA+ G + + LL +GA KD + L ++ G ++V+ LL Q PD G T L ++ G D+ +LL G++ +G TPL A +VKLLL A D G + + VAA L + + +DI LL Y + N I +G+ + +AA EG + +LL +A++++ ++S PL AA V +L GA I K ++ L +++ GN ++++ LL G + G TPLH A+ +G +N+LL+ GA PNE+ +G L ++ + GYI + + L V E++ Sbjct: 430 NIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLKVVTEETL 806 HSP 7 Score: 135.191 bits (339), Expect = 3.609e-31 Identity = 116/421 (27.55%), Postives = 202/421 (47.98%), Query Frame = 2 Query: 2081 MVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIP-LMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQIC-QLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALV 3328 M + A H+ G+ + A+ + S L+ L+ +IN+ + G+N L +A+ EG + L++ AD+D + + L A+ +G EVVR+L+ GA ++ ++GF+ L ++A + + +++ LL G + G TPL +A +G + V+LLL+ N+ R+P L ++ ++ K A L+ + + +S G T L IA LL+RGA N TPLH++ + + ++LL + I+ DG T +H + G +++ L+D GA I K G + LH+ A QG + C QLL+ + +D+ + TAL +A+ GH ++ +L++ AN TP +A K N +K+ LL KHGA + Sbjct: 1 MSEETKEKAAKPAHRKRKGKKSDTNASYLRAARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQ-NDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRG-----SKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHM-ATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASI 409
BLAST of Ankyrin repeat domain 50 vs. Ensembl Xenopus
Match: tpm4 (tropomyosin 4 [Source:Xenbase;Acc:XB-GENE-6077097]) HSP 1 Score: 225.713 bits (574), Expect = 3.908e-59 Identity = 170/569 (29.88%), Postives = 283/569 (49.74%), Query Frame = 2 Query: 1715 DINCVNENGTT--SLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVA---------ALCLNSNSK------------YLDIIK---LLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIA-VLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 D +C+++ T S + AA++G L +G + + +++G +AL LA G++E+V L+ + D D + G TAL A+ G+T++V +L+++G+N+N Q G TPL A + +VK LL+NGA DG + + VA +L L +++K D K LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL G+ I + G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D + N K+ +G T L IA NRL + +E LL GA +G TP+H++ + L H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G D + G T L ++S+EGH ++ ++L+ GA+ + TP VA K I++ LL + A D Sbjct: 5 DGDCLSDQSDTNASYLRAARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRL-KVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVR-----GETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPD 566 HSP 2 Score: 205.682 bits (522), Expect = 7.548e-53 Identity = 157/551 (28.49%), Postives = 255/551 (46.28%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL GA L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL +N N + G TPL A K +++LLL +GA I G + I VAA +++I+ L + + N + G L +AA G + + LL+N A ++ D++PL +A G ++V+ LL GA SG++ L +S+ +G+ + S LL G G TPLH+A+ G+ E V LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G P+H++ + D +LL S N+N + G T +H+A+ + + + L + GA ID T LH+ + G ++ L+ G ++ G T L A+Q+GH I N+L+ GA+ + T +A + +I + + L+ Sbjct: 251 KRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKG-ASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSA-----NVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLK 790 HSP 3 Score: 199.519 bits (506), Expect = 5.237e-51 Identity = 162/581 (27.88%), Postives = 269/581 (46.30%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ G+ ++ TPL A+ + + MVKLLL+ G+ ID + DG + + A S + ++ +LL I G++ L +A +G L C ++LL++N +D V L A AA G+++V ++LL A + +GF+ L I+ + +++ LL G G TP+H+A+ G V+ L GA PN + G L ++ + G ++ L+ + V K+ D T L I+ + V+ LL +GA +G TPLH+S + D VLL+H + I + G T +H+A+ G E++K L+ A D G T LH+ A ++ LL+D G + G T L IA+++ ++I L+ +GA+ I P +A + H+ + +LL A V+ N Sbjct: 100 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGA-----RSGHEQVVGMLLDRGAPILSKTKNGLSPLHMAT-QGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQ-VEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGI-----VTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSN 668 HSP 4 Score: 198.749 bits (504), Expect = 1.059e-50 Identity = 164/566 (28.98%), Postives = 266/566 (47.00%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 +L + R++ + L+ N + + +++G T L +AA G ++ LLL+ GA ++ + L +A G +VKLLL + D DG T L A G +V +LL G+ I + G +PL AT V+LLL + +D ND +A+ VAA C + + K+LL N N G L IA + + ++LL++ A I V S P+ AAF G+ +V L GA+ + + G + L ++A G S+++ LL G + TPLH+++ G+ + V LLK GA P+ G PL LS +EG+ +A L++ S + G T L +A E V+ LL + A +G TPLH++ + YD +V L L + + +G T +HIA+ K +I +L++ GA + +G +HL A +G + LL+ N++ + G T L +A+QE + + +L N GA + TP VA +IK+ L +HG+ V+ K Sbjct: 179 ALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHC-----GHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHG-ASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVA---AHYDNQKVALL--LLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAK 733 HSP 5 Score: 178.718 bits (452), Expect = 1.428e-44 Identity = 138/470 (29.36%), Postives = 215/470 (45.74%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEF-----VEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ + N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L P+ T G TAL AA G++++V LL +G+ + + + +TPL + +V+ LL GAY D G + L L+S + D+ +LL + + ++ +G L +AA G + K+LL+ NA D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G P+HLA+ EG + V+LLL A N + G PL L+ QE + +AE L + DG+T + L+ + V FLL G+ + NG TPLH + Q VLLQH + N +N G TA+ IA G ++ +L Sbjct: 336 DVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYT-----PLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLAN------QGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVN-----GNTALAIARRLGYISVVDTL 789 HSP 6 Score: 145.976 bits (367), Expect = 1.732e-34 Identity = 131/498 (26.31%), Postives = 213/498 (42.77%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 A +G +E L +D + +G AL A+ G +IV L+ G++++ +G T L A+ +V++L+ NGA ++ Q +G + +++AA +L+++K LL + +L +G L +A +G + +LLEN+ + R P L AA + + LLL KSGF+ L I+A GN + + LL RG +D R++ TPLH+AS G V LLL G+K ++ K+ DG T L + + V LL RGA + NG +PLH++ +C Q+LLQH++ +D N+ T LH+ A G Y++ ++L+D N + G T L IA ++ L++ LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 22 AARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAA-----QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDI--TPLHVASKRGNANMVKLLLDRGSK----------------------------------IDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVP--------------------------------------VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNV 438 HSP 7 Score: 144.821 bits (364), Expect = 3.720e-34 Identity = 107/377 (28.38%), Postives = 173/377 (45.89%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESV 2719 N +SQL +G N N G T+L +AA+ G + + LL +GA KD + L ++ G ++V+ LL Q PD G T L ++ G D+ +LL G++ +G TPL A +VKLLL A D G + + VAA L + + +DI LL Y + N I +G+ + +AA EG + +LL +A++++ ++S PL AA V +L GA I K ++ L +++ GN ++++ LL G + G TPLH A+ +G +N+LL+ GA PNE+ +G L ++ + GYI + + L V E++ Sbjct: 421 NIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLKVVTEETL 797
BLAST of Ankyrin repeat domain 50 vs. Ensembl Xenopus
Match: tpm4 (tropomyosin 4 [Source:Xenbase;Acc:XB-GENE-6077097]) HSP 1 Score: 225.713 bits (574), Expect = 4.115e-59 Identity = 170/569 (29.88%), Postives = 283/569 (49.74%), Query Frame = 2 Query: 1715 DINCVNENGTT--SLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVA---------ALCLNSNSK------------YLDIIK---LLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIA-VLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 D +C+++ T S + AA++G L +G + + +++G +AL LA G++E+V L+ + D D + G TAL A+ G+T++V +L+++G+N+N Q G TPL A + +VK LL+NGA DG + + VA +L L +++K D K LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL G+ I + G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D + N K+ +G T L IA NRL + +E LL GA +G TP+H++ + L H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G D + G T L ++S+EGH ++ ++L+ GA+ + TP VA K I++ LL + A D Sbjct: 5 DGDCLSDQSDTNASYLRAARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRL-KVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVR-----GETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPD 566 HSP 2 Score: 205.682 bits (522), Expect = 6.524e-53 Identity = 157/551 (28.49%), Postives = 255/551 (46.28%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL GA L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL +N N + G TPL A K +++LLL +GA I G + I VAA +++I+ L + + N + G L +AA G + + LL+N A ++ D++PL +A G ++V+ LL GA SG++ L +S+ +G+ + S LL G G TPLH+A+ G+ E V LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G P+H++ + D +LL S N+N + G T +H+A+ + + + L + GA ID T LH+ + G ++ L+ G ++ G T L A+Q+GH I N+L+ GA+ + T +A + +I + + L+ Sbjct: 251 KRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKG-ASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSA-----NVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLK 790 HSP 3 Score: 199.519 bits (506), Expect = 5.065e-51 Identity = 162/581 (27.88%), Postives = 269/581 (46.30%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ G+ ++ TPL A+ + + MVKLLL+ G+ ID + DG + + A S + ++ +LL I G++ L +A +G L C ++LL++N +D V L A AA G+++V ++LL A + +GF+ L I+ + +++ LL G G TP+H+A+ G V+ L GA PN + G L ++ + G ++ L+ + V K+ D T L I+ + V+ LL +GA +G TPLH+S + D VLL+H + I + G T +H+A+ G E++K L+ A D G T LH+ A ++ LL+D G + G T L IA+++ ++I L+ +GA+ I P +A + H+ + +LL A V+ N Sbjct: 100 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGA-----RSGHEQVVGMLLDRGAPILSKTKNGLSPLHMAT-QGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQ-VEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGI-----VTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSN 668 HSP 4 Score: 198.749 bits (504), Expect = 1.042e-50 Identity = 164/566 (28.98%), Postives = 266/566 (47.00%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 +L + R++ + L+ N + + +++G T L +AA G ++ LLL+ GA ++ + L +A G +VKLLL + D DG T L A G +V +LL G+ I + G +PL AT V+LLL + +D ND +A+ VAA C + + K+LL N N G L IA + + ++LL++ A I V S P+ AAF G+ +V L GA+ + + G + L ++A G S+++ LL G + TPLH+++ G+ + V LLK GA P+ G PL LS +EG+ +A L++ S + G T L +A E V+ LL + A +G TPLH++ + YD +V L L + + +G T +HIA+ K +I +L++ GA + +G +HL A +G + LL+ N++ + G T L +A+QE + + +L N GA + TP VA +IK+ L +HG+ V+ K Sbjct: 179 ALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDITPLHVASKRGNANMVKLLLDRGSKIDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHC-----GHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHG-ASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVA---AHYDNQKVALL--LLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAK 733 HSP 5 Score: 178.718 bits (452), Expect = 1.371e-44 Identity = 138/470 (29.36%), Postives = 215/470 (45.74%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEF-----VEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ + N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L P+ T G TAL AA G++++V LL +G+ + + + +TPL + +V+ LL GAY D G + L L+S + D+ +LL + + ++ +G L +AA G + K+LL+ NA D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G P+HLA+ EG + V+LLL A N + G PL L+ QE + +AE L + DG+T + L+ + V FLL G+ + NG TPLH + Q VLLQH + N +N G TA+ IA G ++ +L Sbjct: 336 DVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYT-----PLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLAN------QGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVN-----GNTALAIARRLGYISVVDTL 789 HSP 6 Score: 145.976 bits (367), Expect = 1.845e-34 Identity = 131/498 (26.31%), Postives = 213/498 (42.77%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 A +G +E L +D + +G AL A+ G +IV L+ G++++ +G T L A+ +V++L+ NGA ++ Q +G + +++AA +L+++K LL + +L +G L +A +G + +LLEN+ + R P L AA + + LLL KSGF+ L I+A GN + + LL RG +D R++ TPLH+AS G V LLL G+K ++ K+ DG T L + + V LL RGA + NG +PLH++ +C Q+LLQH++ +D N+ T LH+ A G Y++ ++L+D N + G T L IA ++ L++ LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 22 AARSGNLEKALDYLKNGVDINICNQNGLNALHLASKEGHVEIVSELIQRGADVDASTKKGNTALHIASLAGQTEVVRVLVTNGANVNAQSQNGFTPLYMAA-----QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFTARNDI--TPLHVASKRGNANMVKLLLDRGSK----------------------------------IDAKTRDGLTPLHCGARSGHEQVVGMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVP--------------------------------------VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRLKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLNHHGASPNTTNV 438 HSP 7 Score: 144.821 bits (364), Expect = 3.549e-34 Identity = 107/377 (28.38%), Postives = 173/377 (45.89%), Query Frame = 2 Query: 1682 NTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESV 2719 N +SQL +G N N G T+L +AA+ G + + LL +GA KD + L ++ G ++V+ LL Q PD G T L ++ G D+ +LL G++ +G TPL A +VKLLL A D G + + VAA L + + +DI LL Y + N I +G+ + +AA EG + +LL +A++++ ++S PL AA V +L GA I K ++ L +++ GN ++++ LL G + G TPLH A+ +G +N+LL+ GA PNE+ +G L ++ + GYI + + L V E++ Sbjct: 421 NIVSQLNHHGASPNTTNVRGETALHMAARAGQSEVVRFLLQNGAQVEAKAKDDQTPLHISARLGKADIVQQLLKQGAYPDAATTSGYTPLHLSSREGHDDVASVLLEHGASFGIVTKKGFTPLHVAAKYGKIEVVKLLLQKNASPDAAGKSGLTPLHVAAHYDNQKVALLLLDKGASPHGAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAITKQGIAPVHLAAQEGHVDMVSLLLTRSANVNVSNKSGLTPLHLAAQEDRVSVAEVLANQGAVIDGTTKMFYTPLHVASHYGNIKMVTFLLQHGSKVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGASPNEVTVNGNTALAIARRLGYISVVDTLKVVTEETL 797
BLAST of Ankyrin repeat domain 50 vs. Ensembl Mouse
Match: Ankrd50 (ankyrin repeat domain 50 [Source:MGI Symbol;Acc:MGI:2139777]) HSP 1 Score: 705.286 bits (1819), Expect = 0.000e+0 Identity = 392/1038 (37.76%), Postives = 602/1038 (58.00%), Query Frame = 2 Query: 266 LASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDE--NLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIE--VKGILPCEKFGSLNDWSIDDIVKILFESINLVN--------INKLNAKKSFTIFS----TYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 LA HFC A D D+L + FI + + +S + Y + + +L P AFK +LLPLL PP +++Y+L+DS+DE N++ GE+ S S +++LL+ HH FFP WL L+C+ RK++ + + F GFRK LDDL K+Y+++D+Q YIL+R+D+++ L+Q + ET E LN LHIKS+G +YLE VLDG+++ ++ ++ I+ IPG L GLYLW+ + LF Q F V+ I N++L++ + L+ E+Y A+ +++ L + L + LV + H+S EWLLDVK CT KY C+ +GH LA+ + L PL+ + FA HLI S + + A+W++++ ++ + ++P E+ +++++L + VN I + ++ +I + +N + ++ A YS SL + ++ L+ G D+ + +G T L +AA+ G T + N L+ GAN D+DGW+ALR A W G+ EVV LL + D D RTALR AAW G DIVL LL G+ +NK D+EGRT L+AA Y +V+ LL++GA ++H+D DGR+A+ VAALC+ ++ + ++ LL+ ++ D +GM LL+AAYEG + +LLE AD+D D R+PL+AAA G+ VV LLFWGAA+ ID G +VLSI+++QGN +++ LL RGLDE HRD+ G TPLH+A+ EG L++ GA+ NEIDN GRIP +L+ QEG+ + L++ +++ + YDG +L++A L + VE L S GAD +D +GR L+I L++Q + L+ N N+ D +GRTA+H++ W+G E+++ LI A ++ DNE R+ L AWQG ++ QLLI+ G +D TC+QGATAL IA+QEGH+++ +L+ GA+ H D RT +VA K H +I LLEK+GA Sbjct: 71 LAFHFCKAQDSDTLCVGGFIRGLVAQICQSGLL-QGYEDKLRDPAVQSLLEPGECERNPAEAFKRCVLLPLLGMKPPPQSLYLLVDSVDEGCNVVE---GEQTSPSL-----------SGTVAELLAGHHEFFPPWLLLLCSARKQSRAVTKMFSGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAETLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQ-FAKVQPILNVILAACRPLTMTELYHAVWTKNMSLTLEDFQRKLDVLSKLLVDGLGSTKILFHHSFAEWLLDVKHCTQKYLCNAAEGHRMLAMSYTCQARNLTPLEAQEFALHLINSN--LQLEPAELALWMIWNGTPVKDSLSTLIPKEQ----------EVLQLLIRAGAHVNSEDDHTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSL---------DVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDESHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLEN-KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNYKDADGRPTLYILALENQLTMAEYFLE-----NGANVEASDAEGRTALHVSCWQGHVEMVRVLIACHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHVDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGA 1065 HSP 2 Score: 248.44 bits (633), Expect = 1.102e-66 Identity = 177/553 (32.01%), Postives = 287/553 (51.90%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAF-----SGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 LI G +N +E+ TS +V LL +GA+ D +G + L A ++G ++VV LL+S+ D + G T L AA G T +V L+ G+NIN D +G T L +A + +V LL G +D D D R+A+ AA + DI+ LL++ +N DNEG L+ AAY G + + + LL++ A++ D+ R+ L AA G+ VV LL+ GA + DK G + L ++A +G+ ++ LL G D H DN G TPL A+ G VN LL GA + ID+ GR L ++ +G +++ L+D + + + G T L +A E L+ +GA DN+GR P ++ + YDC Q+LL+ N +NI+ DGR A+ +A+ +G +I++ L GA ++ KD +GR L++ A + + + ++ G N++ + ++G TAL ++ +GH+E+ +LI A+V D+ R+ + A H+K+ LL +HGA+VD Sbjct: 463 LIRAGAHVN--SEDDHTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAW-----GGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE-SHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE-----NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNYKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHVEMVRVLIACHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVD 1002 HSP 3 Score: 190.66 bits (483), Expect = 1.491e-48 Identity = 142/463 (30.67%), Postives = 228/463 (49.24%), Query Frame = 2 Query: 1979 DIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSC-----QEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +++ LL+ +G+++N +D + A + D + + LL+NGA ++ D++GR+ + AA S LD++ LL+ ++ + D G L +AA +G + L+ A+I+ D+ + L +AA+ G+ EVV LL+ G + C D + L +A G+ I+ LL G + DN G T L A+ G E V LL GA+ N D GR L ++ +G+ + LID E V+ DG T L +A + V+ LL GAD DNNGRTPL + LL ++ +D +GRT + IAS +G+ E++++L+D G +D+ G T LH+ A++G IC+ LI+ G +E + G +ASQEGH + +L+ +N+ R +VA H I LL HGA V+ K+ Sbjct: 458 EVLQLLIRAGAHVNSEDDHTSCIVRQALEREDSI--RTLLDNGASVNQCDSNGRTLLANAAY-----SGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAE-VDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA-----VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDESHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNYKDA 907 HSP 4 Score: 147.517 bits (371), Expect = 3.324e-35 Identity = 97/303 (32.01%), Postives = 163/303 (53.80%), Query Frame = 2 Query: 1670 QNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVE 2569 Q + + L+ GLD + ++ G T L +AA G IC L+ GA ID DG LA G+ + V++LL K + D G DGR ALR AA G DIV LL S G+++N +D++GR L + M + L NGA ++ D +GR+A+ V+ C +++++++L+ + ++N DNE + L AA++G + ++L+E+ A +D + L AA G+ +VV++LL GA + D+ G + + ++A G+SQI+ L G ++ GC+P + ++E Sbjct: 787 QGNVEVVRTLLDRGLDESHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNYKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVS--CWQG---HVEMVRVLIACHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHVDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLN----GCSPSPVHTME 1080
BLAST of Ankyrin repeat domain 50 vs. Ensembl Mouse
Match: Ank3 (ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]) HSP 1 Score: 230.335 bits (586), Expect = 9.422e-61 Identity = 166/579 (28.67%), Postives = 278/579 (48.01%), Query Frame = 2 Query: 1604 STYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S YS S + ++ + S + R I NG+D+N N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D S N K+ +G T L IA +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L +A++EGH ++ L++ GA++ TP VA K +++ +LL + A D Sbjct: 24 SCYSRSSQKSDANA-SYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPD 586 HSP 2 Score: 212.231 bits (539), Expect = 3.893e-55 Identity = 173/638 (27.12%), Postives = 289/638 (45.30%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDG---------------------RSAIFVA-------ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDD----------------------------DGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNH---IKICNLLEKHGALVDRK 3337 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG RSA ++ L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A + + +PL A V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L +A + FLL GA +I G TPLH++ + + +LLQ S + + + L +G T +HIA+ K +I SL++ GA + +G +HL A +G + LL+ N++ + G T L +A+QE + + +L+N GA H+D+ + Y + G H IKI N L +H A V+ K Sbjct: 120 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGA---HVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAK 753 HSP 3 Score: 200.29 bits (508), Expect = 2.209e-51 Identity = 150/551 (27.22%), Postives = 258/551 (46.82%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL ++ N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L ++A +G+ + + LL G G TPLH+A+ G+ E +LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G TAL A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 271 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG-ASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLK 810 HSP 4 Score: 134.42 bits (337), Expect = 3.838e-31 Identity = 96/348 (27.59%), Postives = 157/348 (45.11%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 S R + + QL+ G N +G T L +AA+ G + LL GA+ + K G++ L +A G +EV LLL + PD G G T L AA + LLLL G++ + G TPL A K + LL GA D + + +A++ L + ++D++ LLL N N+NL + G+ L +AA E + ++L+ A +D + +PL GN ++V LL A ++ K+G++ L +A QG++ I +N+LL++ A PNE+ +G L ++ + GYI + + L Sbjct: 500 SARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGA-----DANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHI---------------------------------INVLLQNNASPNELTVNGNTALAIARRLGYISVVDTL 809 HSP 5 Score: 132.88 bits (333), Expect = 1.371e-30 Identity = 105/398 (26.38%), Postives = 186/398 (46.73%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVVR LL GA+ + GF+ L+++ QG+ Q++S LL + + LH+A+ + + LLL++ + G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL S I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D + + G T L IA ++ + + LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 71 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLN-RAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 458
BLAST of Ankyrin repeat domain 50 vs. Ensembl Mouse
Match: Ank3 (ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]) HSP 1 Score: 230.335 bits (586), Expect = 1.032e-60 Identity = 160/547 (29.25%), Postives = 267/547 (48.81%), Query Frame = 2 Query: 1700 IINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 I NG+D+N N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D S N K+ +G T L IA +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L +A++EGH ++ L++ GA++ TP VA K +++ +LL + A D Sbjct: 44 IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPD 575 HSP 2 Score: 219.55 bits (558), Expect = 2.464e-57 Identity = 166/618 (26.86%), Postives = 289/618 (46.76%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDG---------------------RSAIF-------VAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV*LFYVIDIG 3370 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG RSA ++ L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A + + +PL A V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L +A + FLL GA +I G TPLH++ + + +LLQ S + + G T +H+A+ + ++ L+D GA G T LH+ A + I L+++G + + QG ++ +A+QEGH+++ +LL++ ANV + TP +A + + + + +L GA VD + + + +G Sbjct: 109 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSAS-----PDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG 720 HSP 3 Score: 201.06 bits (510), Expect = 1.158e-51 Identity = 150/551 (27.22%), Postives = 258/551 (46.82%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL ++ N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L ++A +G+ + + LL G G TPLH+A+ G+ E +LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G TAL A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 260 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG-ASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLK 799 HSP 4 Score: 160.229 bits (404), Expect = 4.769e-39 Identity = 129/465 (27.74%), Postives = 211/465 (45.38%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L+ P+ T G TAL AA G+ ++V L+ G+ + + + +TPL + +V+ LL GA + G + + +AA + D+ LL + ++++ +G L +AA G + +LL+ +A D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G +HLA+ EG + V+LLL A N + G PL L+ QE + +AE L++ V+ ++ G T L + + V FLL A + NG T LH + Q VLLQ++ + N +N G TA+ IA G ++ +L Sbjct: 345 DVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAA-----REGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG-AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVN-----GNTALAIARRLGYISVVDTL 798 HSP 5 Score: 133.65 bits (335), Expect = 7.892e-31 Identity = 105/398 (26.38%), Postives = 186/398 (46.73%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVVR LL GA+ + GF+ L+++ QG+ Q++S LL + + LH+A+ + + LLL++ + G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL S I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D + + G T L IA ++ + + LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 60 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLN-RAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 447 HSP 6 Score: 125.561 bits (314), Expect = 2.174e-28 Identity = 94/347 (27.09%), Postives = 162/347 (46.69%), Query Frame = 2 Query: 2354 MAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLN------------------RLP-----------EFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 + AA +G+ E + G ++ +++G + L +++ +G+ +++SELL R + G T LH+AS+ GQ E V +L+ +GA N +G PL ++ QE ++++ L+D S + + DG T L +A+ RLP + LL +A ++ +G TPLHI+ + +LL + + N + T +H+AS +G+ ++K L+D GA+ID K +G T LH GA G Q+ ++L+D I G + L +A+Q HL LL+ V + + T VA H K+ +L Sbjct: 29 LRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNG-ASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-----TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 369
BLAST of Ankyrin repeat domain 50 vs. Ensembl Mouse
Match: Ank3 (ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]) HSP 1 Score: 229.18 bits (583), Expect = 2.221e-60 Identity = 160/547 (29.25%), Postives = 267/547 (48.81%), Query Frame = 2 Query: 1700 IINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 I NG+D+N N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D S N K+ +G T L IA +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L +A++EGH ++ L++ GA++ TP VA K +++ +LL + A D Sbjct: 44 IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPD 575 HSP 2 Score: 218.009 bits (554), Expect = 7.011e-57 Identity = 166/618 (26.86%), Postives = 289/618 (46.76%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDG---------------------RSAIF-------VAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV*LFYVIDIG 3370 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG RSA ++ L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A + + +PL A V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L +A + FLL GA +I G TPLH++ + + +LLQ S + + G T +H+A+ + ++ L+D GA G T LH+ A + I L+++G + + QG ++ +A+QEGH+++ +LL++ ANV + TP +A + + + + +L GA VD + + + +G Sbjct: 109 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSAS-----PDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG 720 HSP 3 Score: 199.904 bits (507), Expect = 2.934e-51 Identity = 150/551 (27.22%), Postives = 258/551 (46.82%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL ++ N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L ++A +G+ + + LL G G TPLH+A+ G+ E +LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G TAL A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 260 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG-ASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLK 799 HSP 4 Score: 159.458 bits (402), Expect = 9.236e-39 Identity = 129/465 (27.74%), Postives = 211/465 (45.38%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L+ P+ T G TAL AA G+ ++V L+ G+ + + + +TPL + +V+ LL GA + G + + +AA + D+ LL + ++++ +G L +AA G + +LL+ +A D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G +HLA+ EG + V+LLL A N + G PL L+ QE + +AE L++ V+ ++ G T L + + V FLL A + NG T LH + Q VLLQ++ + N +N G TA+ IA G ++ +L Sbjct: 345 DVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAA-----REGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG-AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVN-----GNTALAIARRLGYISVVDTL 798 HSP 5 Score: 132.88 bits (333), Expect = 1.500e-30 Identity = 105/398 (26.38%), Postives = 186/398 (46.73%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVVR LL GA+ + GF+ L+++ QG+ Q++S LL + + LH+A+ + + LLL++ + G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL S I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D + + G T L IA ++ + + LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 60 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLN-RAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 447 HSP 6 Score: 125.176 bits (313), Expect = 3.251e-28 Identity = 94/347 (27.09%), Postives = 162/347 (46.69%), Query Frame = 2 Query: 2354 MAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLN------------------RLP-----------EFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 + AA +G+ E + G ++ +++G + L +++ +G+ +++SELL R + G T LH+AS+ GQ E V +L+ +GA N +G PL ++ QE ++++ L+D S + + DG T L +A+ RLP + LL +A ++ +G TPLHI+ + +LL + + N + T +H+AS +G+ ++K L+D GA+ID K +G T LH GA G Q+ ++L+D I G + L +A+Q HL LL+ V + + T VA H K+ +L Sbjct: 29 LRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNG-ASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-----TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 369
BLAST of Ankyrin repeat domain 50 vs. Ensembl Mouse
Match: Ank3 (ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]) HSP 1 Score: 229.18 bits (583), Expect = 2.351e-60 Identity = 160/547 (29.25%), Postives = 267/547 (48.81%), Query Frame = 2 Query: 1700 IINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 I NG+D+N N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D S N K+ +G T L IA +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L +A++EGH ++ L++ GA++ TP VA K +++ +LL + A D Sbjct: 44 IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPD 575 HSP 2 Score: 218.009 bits (554), Expect = 6.892e-57 Identity = 166/618 (26.86%), Postives = 289/618 (46.76%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDG---------------------RSAIF-------VAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV*LFYVIDIG 3370 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG RSA ++ L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A + + +PL A V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L +A + FLL GA +I G TPLH++ + + +LLQ S + + G T +H+A+ + ++ L+D GA G T LH+ A + I L+++G + + QG ++ +A+QEGH+++ +LL++ ANV + TP +A + + + + +L GA VD + + + +G Sbjct: 109 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSAS-----PDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG 720 HSP 3 Score: 199.904 bits (507), Expect = 3.639e-51 Identity = 150/551 (27.22%), Postives = 258/551 (46.82%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL ++ N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L ++A +G+ + + LL G G TPLH+A+ G+ E +LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G TAL A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 260 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG-ASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLK 799 HSP 4 Score: 159.458 bits (402), Expect = 1.056e-38 Identity = 129/465 (27.74%), Postives = 211/465 (45.38%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L+ P+ T G TAL AA G+ ++V L+ G+ + + + +TPL + +V+ LL GA + G + + +AA + D+ LL + ++++ +G L +AA G + +LL+ +A D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G +HLA+ EG + V+LLL A N + G PL L+ QE + +AE L++ V+ ++ G T L + + V FLL A + NG T LH + Q VLLQ++ + N +N G TA+ IA G ++ +L Sbjct: 345 DVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAA-----REGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG-AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVN-----GNTALAIARRLGYISVVDTL 798 HSP 5 Score: 132.88 bits (333), Expect = 1.492e-30 Identity = 105/398 (26.38%), Postives = 185/398 (46.48%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVVR LL GA+ + GF+ L+++ QG+ Q++S LL + LH+A+ + + LLL++ + G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL S I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D + + G T L IA ++ + + LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 60 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDT----KGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRA-AAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 447 HSP 6 Score: 124.79 bits (312), Expect = 3.629e-28 Identity = 94/347 (27.09%), Postives = 162/347 (46.69%), Query Frame = 2 Query: 2354 MAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLN------------------RLP-----------EFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 + AA +G+ E + G ++ +++G + L +++ +G+ +++SELL R + G T LH+AS+ GQ E V +L+ +GA N +G PL ++ QE ++++ L+D S + + DG T L +A+ RLP + LL +A ++ +G TPLHI+ + +LL + + N + T +H+AS +G+ ++K L+D GA+ID K +G T LH GA G Q+ ++L+D I G + L +A+Q HL LL+ V + + T VA H K+ +L Sbjct: 29 LRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNG-ASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-----TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 369
BLAST of Ankyrin repeat domain 50 vs. UniProt/SwissProt
Match: sp|Q9ULJ7|ANR50_HUMAN (Ankyrin repeat domain-containing protein 50 OS=Homo sapiens OX=9606 GN=ANKRD50 PE=1 SV=4) HSP 1 Score: 705.286 bits (1819), Expect = 0.000e+0 Identity = 393/1038 (37.86%), Postives = 601/1038 (57.90%), Query Frame = 2 Query: 266 LASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDE--NLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIE--VKGILPCEKFGSLNDWSIDDIVKILFESINLVN--------INKLNAKKSFTIFS----TYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 LA HFC A D D+L + FI + + +S + Y + + +L P AFK +LLPLL PP +++Y+L+DS+DE N+ GE+ S S ++ LL+ HH FFP WL L+C+ RK+++ + + F GFRK LDDL K+Y+++D+Q YIL+R+D+++ L+Q + ET E+LN LHIKS+G +YLE VLDG+++ ++ ++ I+ IPG L GLYLW+ + LF Q F V+ I N++L++ + L+ E+Y A+ +++ L + L + LV N H S EWLLDVK CT KY C+ +GH LA+ + L PL+ + FA HLI S + + A+W++++ + + ++P E+ +++++L ++ VN I + ++ +I + +N + ++ A YS SL + ++ L+ G D+ + +G T L +AA+ G T + N L+ GAN D+DGW+ALR A W G+ EVV LL + D D RTALR AAW G DIVL LL G+ +NK D+EGRT L+AA Y +V+ LL++GA ++H+D DGR+A+ VAALC+ ++ + ++ LL+ ++ D +GM LL+AAYEG + +LLE AD+D D R+PL+AAA G+ VV LLFWGAA+ ID G +VLSI+++QGN +++ LL RGLDE HRD+ G TPLH+A+ EG L++ GA+ NEIDN GRIP +L+ QEG+ + L++ +++ + YDG +L++A L + VE L S GAD +D +GR L+I L++Q + L+ N N+ D +GRTA+H++ W+G E+++ LI A ++ DNE R+ L AWQG ++ QLLI+ G +D TC+QGATAL IA+QEGH+++ +L+ GA+ H D RT +VA K H +I LLEK+GA Sbjct: 108 LAFHFCKAQDSDTLCVGGFIRGLVAQICRSGLL-QGYEDKLRDPAVQSLLQPGECERNPAEAFKRCVLLPLLGMKPPQQSLYLLVDSVDEGCNITE---GEQTSTSL-----------SGTVAALLAGHHEFFPPWLLLLCSARKQSKAVTKMFTGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAEMLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQ-FAKVQPILNVILAACRPLTITELYHAVWTKNMSLTLEDFQRKLDILSKLLVDGLGNTKILFHYSFAEWLLDVKHCTQKYLCNAAEGHRMLAMSYTCQAKNLTPLEAQEFALHLINSN--LQLETAELALWMIWNGTPVRDSLSTLIPKEQ----------EVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSL---------DVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLEN-KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLE-----NGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGA 1102 HSP 2 Score: 253.447 bits (646), Expect = 2.154e-67 Identity = 177/553 (32.01%), Postives = 288/553 (52.08%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAF-----SGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 L+ G +N +E+ TS +V LL +GA+ D +G + L A ++G ++VV LL+S+ D + G T L AA G T +V L+ G+NIN D +G T L +A + +V LL G +D D D R+A+ AA + DI+ LL++ +N DNEG L+ AAY G + + + LL++ A++ D+ R+ L AA G+ VV LL+ GA + DK G + L ++A +G+ ++ LL G D H DN G TPL A+ G VN LL GA + ID+ GR L ++ +G +++ L+D + N + G T L +A E L+ +GA DN+GR P ++ + YDC Q+LL+ N +NI+ DGR A+ +A+ +G +I++ L GA ++ KD +GR L++ A + + + ++ G N++ + ++G TAL ++ +GH+E+ +LI + A+V D+ R+ + A H+K+ LL +HGA+VD Sbjct: 500 LVKAGAHVN--SEDDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAW-----GGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE-NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE-----NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVD 1039 HSP 3 Score: 191.045 bits (484), Expect = 9.295e-48 Identity = 142/463 (30.67%), Postives = 229/463 (49.46%), Query Frame = 2 Query: 1979 DIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSC-----QEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +++ LL+ +G+++N +D + A + D + + LL+NGA ++ D++GR+ + AA S LD++ LL+ ++ + D G L +AA +G + L+ A+I+ D+ + L +AA+ G+ EVV LL+ G + C D + L +A G+ I+ LL G + DN G T L A+ G E V LL GA+ N D GR L ++ +G+ + LID E V+ DG T L +A + V+ LL GAD DNNGRTPL + LL ++ +D +GRT + IAS +G+ E++++L+D G + +D+ G T LH+ A++G IC+ LI+ G +E + G +ASQEGH + +L+ +N+ R +VA H I LL HGA V+ K+ Sbjct: 495 EVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSI--RTLLDNGASVNQCDSNGRTLLANAAY-----SGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAE-VDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA-----VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDA 944 HSP 4 Score: 152.91 bits (385), Expect = 5.930e-36 Identity = 99/303 (32.67%), Postives = 164/303 (54.13%), Query Frame = 2 Query: 1670 QNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVE 2569 Q + + L+ GLD N ++ G T L +AA G IC L+ GA ID DG LA G+ + V++LL K + D G DGR ALR AA G DIV LL S G+++N +D++GR L + M + L NGA ++ D +GR+A+ V+ C +++++++L+ Y+ ++N DNE + L AA++G + ++L+E+ A +D + L AA G+ +VV++LL GA + D+ G + + ++A G+SQI+ L G ++ GC+P + ++E Sbjct: 824 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVS--CWQG---HMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLN----GCSPSPVHTME 1117
BLAST of Ankyrin repeat domain 50 vs. UniProt/SwissProt
Match: sp|G5E8K5|ANK3_MOUSE (Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV=1) HSP 1 Score: 229.18 bits (583), Expect = 1.645e-59 Identity = 160/547 (29.25%), Postives = 267/547 (48.81%), Query Frame = 2 Query: 1700 IINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 I NG+D+N N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D S N K+ +G T L IA +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L +A++EGH ++ L++ GA++ TP VA K +++ +LL + A D Sbjct: 44 IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPD 575 HSP 2 Score: 218.009 bits (554), Expect = 4.821e-56 Identity = 166/618 (26.86%), Postives = 289/618 (46.76%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDG---------------------RSAIF-------VAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV*LFYVIDIG 3370 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG RSA ++ L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A + + +PL A V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L +A + FLL GA +I G TPLH++ + + +LLQ S + + G T +H+A+ + ++ L+D GA G T LH+ A + I L+++G + + QG ++ +A+QEGH+++ +LL++ ANV + TP +A + + + + +L GA VD + + + +G Sbjct: 109 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSAS-----PDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG 720 HSP 3 Score: 199.904 bits (507), Expect = 2.545e-50 Identity = 150/551 (27.22%), Postives = 258/551 (46.82%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL ++ N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L ++A +G+ + + LL G G TPLH+A+ G+ E +LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G TAL A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 260 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG-ASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLK 799 HSP 4 Score: 159.458 bits (402), Expect = 7.385e-38 Identity = 129/465 (27.74%), Postives = 211/465 (45.38%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L+ P+ T G TAL AA G+ ++V L+ G+ + + + +TPL + +V+ LL GA + G + + +AA + D+ LL + ++++ +G L +AA G + +LL+ +A D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G +HLA+ EG + V+LLL A N + G PL L+ QE + +AE L++ V+ ++ G T L + + V FLL A + NG T LH + Q VLLQ++ + N +N G TA+ IA G ++ +L Sbjct: 345 DVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAA-----REGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG-AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVN-----GNTALAIARRLGYISVVDTL 798 HSP 5 Score: 132.88 bits (333), Expect = 1.043e-29 Identity = 105/398 (26.38%), Postives = 185/398 (46.48%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVVR LL GA+ + GF+ L+++ QG+ Q++S LL + LH+A+ + + LLL++ + G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL S I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D + + G T L IA ++ + + LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 60 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDT----KGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRA-AAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 447 HSP 6 Score: 124.79 bits (312), Expect = 2.538e-27 Identity = 94/347 (27.09%), Postives = 162/347 (46.69%), Query Frame = 2 Query: 2354 MAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLN------------------RLP-----------EFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 + AA +G+ E + G ++ +++G + L +++ +G+ +++SELL R + G T LH+AS+ GQ E V +L+ +GA N +G PL ++ QE ++++ L+D S + + DG T L +A+ RLP + LL +A ++ +G TPLHI+ + +LL + + N + T +H+AS +G+ ++K L+D GA+ID K +G T LH GA G Q+ ++L+D I G + L +A+Q HL LL+ V + + T VA H K+ +L Sbjct: 29 LRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNG-ASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-----TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 369
BLAST of Ankyrin repeat domain 50 vs. UniProt/SwissProt
Match: sp|Q12955|ANK3_HUMAN (Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3 PE=1 SV=3) HSP 1 Score: 226.868 bits (577), Expect = 1.435e-58 Identity = 160/547 (29.25%), Postives = 268/547 (48.99%), Query Frame = 2 Query: 1700 IINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 I NG+DIN N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D + N K+ +G T L IA + +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L ++++EGH ++ L++ GA++ TP VA K +++ NLL + A D Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDK-KANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPD 592 HSP 2 Score: 215.312 bits (547), Expect = 5.672e-55 Identity = 172/664 (25.90%), Postives = 300/664 (45.18%), Query Frame = 2 Query: 1526 INLVNINKLNAKK--SFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKI-----------------------------DPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 IN+ N N LNA S + + +N AT + +L + + L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL + D G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG + + A L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A+ + + +PL A +V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L ++ + FLL GA +I G TPLH++ + + +LLQ S + + G T +H+A+ + ++ L+D GA G T LH+ A + I L+++G + + QG ++ +A+QEGH+++ +LL+ ANV + TP +A + + + + +L GA VD Sbjct: 67 INICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQ-QGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASP-----DAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVD 724 HSP 3 Score: 201.06 bits (510), Expect = 1.396e-50 Identity = 152/551 (27.59%), Postives = 257/551 (46.64%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL +N N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L +SA +G+ + + LL G G TPLH+A+ G+ E NLLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G T L A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 277 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD-QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 816 HSP 4 Score: 162.54 bits (410), Expect = 8.972e-39 Identity = 130/465 (27.96%), Postives = 213/465 (45.81%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y L+ + N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L+ P+ T G TAL AA G+ ++V L+ G+ + + + +TPL + +V+ LL GA + G + L L++ + D+ LL + ++++ +G L +AA G + +LL+ +A D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G +HLA+ EG + V+LLL A N + G PL L+ QE + +AE L++ V+ ++ G T L + + V FLL A + NG TPLH + Q VLLQ++ + N +N G TA+ IA G ++ +L Sbjct: 362 DVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYT-----PLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAH-VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVN-----GNTALGIARRLGYISVVDTL 815 HSP 5 Score: 134.035 bits (336), Expect = 4.866e-30 Identity = 108/419 (25.78%), Postives = 196/419 (46.78%), Query Frame = 2 Query: 2096 LNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 + NG I+ + +G +A+ +A S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVV+ LL GA+ + GF+ L+++ QG+ Q++S LL R LH+A+ + + LLL++ + G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL + I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D N + G T L IA ++ +++ LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 61 IKNGVDINICNQNGLNALHLA-----SKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVR----LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNR-AAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 464 HSP 6 Score: 129.798 bits (325), Expect = 1.066e-28 Identity = 102/387 (26.36%), Postives = 175/387 (45.22%), Query Frame = 2 Query: 2354 MAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLN------------------RLPEF-----------VEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLID---------------------------------FGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALV 3328 + AA +G+ E + G I+ +++G + L +++ +G+ +++SELL R + G T LH+AS+ GQ E V +L+ +GA N +G PL ++ QE ++++ + L+D S + + DG T L +A+ RLP LL +A ++ +G TPLHI+ + +LL + + N + T +H+AS +G+ ++K L+D GA+ID K +G T LH GA G Q+ ++L+D + +D+ + TAL +A+ GH ++ +L++ AN TP +A K N IK+ LL KHGA + Sbjct: 46 LRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDN-GASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-----TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASI 426
BLAST of Ankyrin repeat domain 50 vs. UniProt/SwissProt
Match: sp|O70511|ANK3_RAT (Ankyrin-3 OS=Rattus norvegicus OX=10116 GN=Ank3 PE=1 SV=3) HSP 1 Score: 221.476 bits (563), Expect = 6.284e-57 Identity = 159/555 (28.65%), Postives = 267/555 (48.11%), Query Frame = 2 Query: 1700 IINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCN--------INLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 I NG+D+N N+NG +L +A++ G + + LL AN K G +AL +A G EVVK+L++ + + +G T L AA ++V LL +G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N +N G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I + G + L A G+ Q++ LL R + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ L+D + N K+ +G T L IA +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E+++ L+ GA+++ K + +T LH+ A G I Q L+ G + + + G T L ++++EGH ++ L++ GA++ TP VA K +++ +LL + A D Sbjct: 61 IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADIESKMVVNRATESGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVR-----GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPD 600 HSP 2 Score: 211.075 bits (536), Expect = 9.141e-54 Identity = 165/626 (26.36%), Postives = 291/626 (46.49%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKIDPDFTG----ND-----------------GRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDG---------------------RSAIF-------VAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV*LFYVIDIG 3370 L+ NG ++N ++NG T L +AAQ + LL +GA+Q + +DG++ L +A+ G+ +VV LLL ++K D ND G T L AA G ++ LLL+ + ++ TPL A+ + + MVKLLL+ GA ID + DG R+A ++ L + + +L+ ++LLL++N ++ + N+ + L +AA+ G + K+LL+ A+ + + +PL A V+ LLL GA+I + +SG + + ++A G+ I+S+L+ G + G T LH+A+ GQ E V L++ GA+ + PL +S + G I ++L+ S N + G T L ++ + FLL GA +I G TPLH++ + + +LLQ S + + G T +H+A+ + ++ L+D GA G T LH+ A + I L+++G + + QG ++ +A+QEGH+++ +LL++ ANV + TP +A + + + + +L GA VD + + + +G Sbjct: 126 LVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADIESKMVVNRATESGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSAS-----PDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG 745 HSP 3 Score: 202.601 bits (514), Expect = 4.536e-51 Identity = 162/546 (29.67%), Postives = 258/546 (47.25%), Query Frame = 2 Query: 1718 INCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNH---IKICNLLEKHGALVDRK 3337 +N E+G T L +AA G ++ LLL+ A ++ + L +A G +VKLLL + D DG T L A G +V +LL + I + G +PL AT V+LLL + +D ND +A+ VAA C + + K+LL N N G L IA + + ++LL++ A I V S P+ AAF G+ +V L+ GA+ + + G + L ++A G ++++ L+ G + TPLH+++ G+ + V LL+ GA PN G PL LS +EG+ +A L+D S++ + G T L +A E LL + A +G TPLH++ + YD +V L L + + +G T +HIA+ K +I SL++ GA + +G +HL A +G + LL+ N++ + G T L +A+QE + + +L+N GA H+D+ + Y + G H IKI N L +H A V+ K Sbjct: 236 VNRATESGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHC-----GHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG-ASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVA---AHYDNQKVALL--LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGA---HVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAK 767 HSP 4 Score: 200.29 bits (508), Expect = 1.918e-50 Identity = 151/551 (27.40%), Postives = 257/551 (46.64%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 ++ + N + L+ G I+ +G T L A++G + +LL A L K+G S L +A ++ V+LLL + D ND TAL AA G + +LL +N N + G TPL A K +++LLL +GA I G + I VAA +++I+ L+ + + N + G L +AA G + + L+++ A ++ D++PL +A G ++V+ LL GA+ + SG++ L +SA +G+ + + LL G G TPLH+A+ G+ E +LLL+ A P+ G PL ++ K+A L+D S + + +G T L IA + LL GADA G +H++ + D +LL + N+N + G T +H+A+ + + + L++ GA +D + G T LH+G G +I L+ ++ G T L A+Q+GH I N+L+ A+ + T +A + +I + + L+ Sbjct: 285 KRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFM-----GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQG-ASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNA-----NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLK 824 HSP 5 Score: 160.614 bits (405), Expect = 3.821e-38 Identity = 129/455 (28.35%), Postives = 208/455 (45.71%), Query Frame = 2 Query: 1631 TNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKG 2986 TN Y +L + Y L+ + N NG T L +A + + LLL GA+ + + G + + +A + G++ +V L+ P+ T G TAL AA G+ ++V L+ G+ + + + +TPL + +V+ LL GA + G + L L++ + D+ LL + ++++ +G L +AA G + +LL+ +A D +S PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G D G +HLA+ EG + V+LLL A N + G PL L+ QE + +AE L++ V+ ++ G T L + + V FLL A + NG TPLH + Q VLLQ++ + N +N G TA+ IA G Sbjct: 372 TNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYT-----PLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG-AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVN-----GNTALAIARRLG 815 HSP 6 Score: 132.494 bits (332), Expect = 1.464e-29 Identity = 95/348 (27.30%), Postives = 157/348 (45.11%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 S R + + QL+ G N +G T L ++A+ G + LL GA+ + K G++ L +A G +EV LLL + PD G G T L AA + LLLL G++ + G TPL A K + LL GA D + + +A++ L + ++D++ LLL N N+NL + G+ L +AA E + ++L+ A +D + +PL GN ++V LL A ++ K+G++ L +A QG++ I +N+LL++ A PNE+ +G L ++ + GYI + + L Sbjct: 514 SARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGA-----DANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHI---------------------------------INVLLQNNASPNELTVNGNTALAIARRLGYISVVDTL 823 HSP 7 Score: 129.028 bits (323), Expect = 1.764e-28 Identity = 106/406 (26.11%), Postives = 185/406 (45.57%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKP--------NEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L S +++++ LL+ N++ +G L IA+ G + K+L+ N A+++ + +PL AA + EVVR LL GA+ + GF+ L+++ QG+ Q++S LL + LH+A+ + + LLL++ N G PL ++ G I +A L++ +V+F + + T L +A V+ LL RGA + +G TPLH ++LL + I +G + +H+A+ ++ L+ +D N+ T LH+ A G Y++ ++L+D N + G T L IA ++ + + LL+ GA++ + TP VA H+ I + L HGA + NV Sbjct: 77 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDT----KGKVRLPALHIAARKDDTKAAALLLQNDTNADIESKMVVNRATESGFTPLHIAAHYGNINVATLLLNRA-AAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP-----ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNV 472
BLAST of Ankyrin repeat domain 50 vs. UniProt/SwissProt
Match: sp|Q5F478|ANR44_CHICK (Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B OS=Gallus gallus OX=9031 GN=ANKRD44 PE=2 SV=1) HSP 1 Score: 214.542 bits (545), Expect = 1.317e-55 Identity = 173/606 (28.55%), Postives = 286/606 (47.19%), Query Frame = 2 Query: 1685 TISQ-LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALC-----------LNSNSKYLD------------IIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI-----DIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNF-GCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLID------------------------------VGA----RIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFG-ANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 T SQ LI NG +I+CV+++G T L VAA+ G + N L++SGA+ L LA N + + + LLS + D + GRT L AA G + + LL SSG++ NK+D GRTPL A C + ++ L+ GA I+ D+ GR+ + AA + N++ L+ ++ LL+ + N ++ D EG N + AA G + ++LLE N+++ +SPL AA++G+ + + +LL + D+ G + L ++A +G+++ + L+++G +DN TPLH + + G C+ LLL+ P+ D G+ PLML+ G+I L++ SV+ G T+L ++ E V+ LL + +D GRTPLH + + LLQ +L+ + + D+ G T +H A + G I+ L++ +GA ++ KD++GRT LH A+ + QLL+ ++ G TAL +A+Q GH+ + L+N A++ D T +A H K C LL Sbjct: 320 TRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEMKEKEAALCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLE-KEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSE--EDCSLKDNQGYTPLHWACYNGHENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKGHEK-CALL 921 HSP 2 Score: 211.846 bits (538), Expect = 7.676e-55 Identity = 174/632 (27.53%), Postives = 282/632 (44.62%), Query Frame = 2 Query: 1634 NVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLD----------EMH-----------------------RDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLI---------DVWPESV----------NFKSYDGSTSLKIAVLNRLPEF--------VEFLLSRGADATIQDNNG-----------------------------------RTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDN-EGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANV 3229 N++ L ++ S + LI + D+N ++N T L VAA N +++ ++ + D+ G +AL A NG++E+V LLL++ + + R AL AA++G ++V LL++ G+ + +D +G TPL AA +VK LLN G ID + G +A+ +A C N ++ L+ Y N+N +N G L AA LC ++L+ N AD++I +SPL A G F + L+ G I C+DK G + L ++A G+ +++ L+ G D +H D+FG T LH A+ G EC+ LL SGA N+ D GR PL + + E L+ D W + K+ G++ L R E +EFLL A+ +IQD G ++PLH++ + +VLLQ ++ +++ D+ GRTA+ +A++KG E +++LI GA + +KDN RT LH G +LL++ N D T ++G T L +A GH++ +LL+ A+V Sbjct: 72 NMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAAASNGQINIVKHLLNLGVEIDEMNIYGNTALHIA--CYNGQDS---VVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEMKEKEAALCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQ-----SLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLEKEASV 693 HSP 3 Score: 181.8 bits (460), Expect = 3.326e-45 Identity = 138/486 (28.40%), Postives = 237/486 (48.77%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 AI++G E +++L+ + D + + RT L A+++G DI+ LL+ SG+ +N +D+ TPL A V++L+ + A ++ +D + ++ + VAA +K L ++++ ++N+ D G L AA G + +LL A+I D DR L AA+ G+ EVV LL+ GA + C DK G++ L +AS G I+ LL G++ + +G T LH+A GQ VN L+ GA N+ +N+G PL + + + +L+ VN +S DG + L + ++ + L+ G + D +G TPLH++ ++Y ++L+ +T + C +H+A+ + + L+ G ID D+ GRT LH A G + +LL G + ++ +G T L A+ H L+ GAN+ D RTP A + + N+L Sbjct: 15 AIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAA-----NKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAAASNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVA---ARYG-HELLINTLITSGADTAKC-GIHNMFPLHLAALNAHSDCCRKLLSSGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNIL 490 HSP 4 Score: 159.073 bits (401), Expect = 4.501e-38 Identity = 147/512 (28.71%), Postives = 225/512 (43.95%), Query Frame = 2 Query: 1652 LFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAW---IGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYE-CVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIAS 3175 L ++I I LI D+N ++ T L VA+ G I LL+ SGA D + L A+ + E V++L+ D + + +T L AA + +I++ +LSS +N D GRT L A MV LLL GA I+ D R A+ AA +L+++ LL+ + G+++ CK D +PL AAA +G +V+ LL G I ++ G + L I+ G +++EL+ G + +N G TPLH A+ C+ LL+ +GA N G+ PL ++ G ++ LI E ++ DG+T L +A + L++ GAD + PLH++ L + DC + LL I+ D GRT +H A+ G+ E IK L GA + KD GRT LH A + + L+ G NI+ET G T L A+ Sbjct: 12 LVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSS---VNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYM-----GHLEVVALLINH---------------------GAEVTCK---------DKKGYTPLHAAASNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE-IDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGF-----EIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAA 479 HSP 5 Score: 151.754 bits (382), Expect = 8.580e-36 Identity = 144/541 (26.62%), Postives = 249/541 (46.03%), Query Frame = 2 Query: 1679 YNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQD--SEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEI---DNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGST--SLKIAVLNRLPEFVEFLLSRGADATI---QDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVG-ARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGIN----IDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDS 3244 ++ I L+ G +IN ++ G T L AA + N+L +S N +++ + A ++ LL +P +G + AA G + LLL SN+ ++ S ++PL A Y + +++LL + +D +D GR+A+ +AA + + ++ L+ ++ + DN L A+ C ++LLE + D+ D ++PLM A G+ + V LLL A++ D G + L G+ + + LL + + + +D G TPLH A+ G ++ LL+ + DN G PL +C G+ E I+V E F+ + G++ L AV+N L+ DA+I +D+ GRTPLH + +C Q+LL HS +N +D G+TA+ +A+ G + L+++ A + L+D + T LHL + +G ++ C LLI I I+ + T L IA++ G + L+ GA V +D Sbjct: 451 FHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEMKEKEAAL-----CLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAF-----KGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLEKEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGH----ENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIG-AIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSA-----QVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKG-HEKCALLILDKIQEQSLINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAVDE 970 HSP 6 Score: 143.28 bits (360), Expect = 3.131e-33 Identity = 93/304 (30.59%), Postives = 151/304 (49.67%), Query Frame = 2 Query: 2321 ADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEIC-NLLINFGANV 3229 A + + D+ PL+ A FSG+ E +R+L++ ++ +D + L +++ G++ I+ L+ G +DN TPLH A E V +L+K A N D + + PL ++ +K AE +I + SVN G T+L A LN E V LL++GA+ D R LH + + +L+ H + C D G T +H A+ G I+K L+++G ID + G T LH+ + G + LID+G N+++ + G T L A+ H +C LL+N GA+V Sbjct: 2 AVLKLADQPPLVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPML-SSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGA-----EVTCKDKKGYTPLHAAASNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADV 299 HSP 7 Score: 140.969 bits (354), Expect = 1.577e-32 Identity = 115/438 (26.26%), Postives = 209/438 (47.72%), Query Frame = 2 Query: 2039 RTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYD-CFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 + PL+ A + D +++L+ ++ D + R+ + VA+ ++ DII+LL+ +N DN + L A S+ ++L++++AD++ D+ +PL AA + + +++ ++++ D+ G + L +A G+ ++++ LLA+G + D LH A+ G E V LL+ GA+ D G PL + G I I + L+++ E Y G+T+L IA N V L+ GA+ +NNG TPLH + + C ++L+ N ++N DG++ +H+ + G ++LI G ID D +G T LH+ A G + LI G + + L +A+ H + C L++ G + DS RT A G +++ LL+ GA ++K+ Sbjct: 9 QPPLVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDA-----DIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAAASNGQINIVKHLLNLGVEIDEMNIY-GNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVN-----NGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKD 435 HSP 8 Score: 105.145 bits (261), Expect = 1.762e-21 Identity = 114/467 (24.41%), Postives = 189/467 (40.47%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSA----LRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDS-EGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAFSGNFE-VVRLLLFWGAAIHCI--DKSGFSVLSISASQGNSQILSELLAR---------GLDEMH-------------------------RDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLK------------------------------------IAVLNRLPEFVEFLLSRGA-----DATIQDNNG 2839 L+ N + + ++ G ++ AA G LLL +N M ++ SA L LA +NG+ + +++LL +D D GRTAL AA+ G + V L+S G+++ +D+ RTPL A+ ++LLL D D G++ + +A ++D + LLL +++ D G L G + ++LLE I D R+PL AA G+ + LL + C D G++ L + G+ + LL + +H +D+ G TPLH A+ EC+ LLL A+ N +D+ G+ LM++ Q G++ + L+++ + + D +TSL IA N L VE LL++GA D + +NG Sbjct: 518 LLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSN--MFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVA-----YGHIDAVSLLLEKEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGHENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKGHEKCALLILDKIQEQSLINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAVDENVSRSNG 977 HSP 9 Score: 90.8929 bits (224), Expect = 4.817e-17 Identity = 65/211 (30.81%), Postives = 99/211 (46.92%), Query Frame = 2 Query: 2711 ESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 E VN + T L +A + +E L+ GA +DN TPLH +V + QVL++HS ++N D + +T +H+A+ + + +I + + +++ D GRT LH A G ++ LL+ G NI+ + AL A+ GHLE+ LLIN GA V D TP A I I L G +D N+ Sbjct: 32 EDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSA-----DVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAAASNGQINIVKHLLNLGVEIDEMNI 237
BLAST of Ankyrin repeat domain 50 vs. TrEMBL
Match: A0A1S3H8J0 (ankyrin repeat domain-containing protein 50 OS=Lingula unguis OX=7574 GN=LOC106153074 PE=4 SV=1) HSP 1 Score: 747.658 bits (1929), Expect = 0.000e+0 Identity = 414/1068 (38.76%), Postives = 630/1068 (58.99%), Query Frame = 2 Query: 188 KSTICRLLTTELTIDCFKTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNY-PDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALL--NLDINTDLYYLK-DMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIE---VKGILPCEKFGSLNDWSIDDIVKILFES-INLVNINKLNAKKSFTIFSTYILNITSTYS---------NSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYL--DIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGAL 3325 K+ +C +T + Q L +LA HFC A DI++L+L FI + + KS E Y R++ S L + C PD AFK G+L PLLS PPP++N++IL+DSIDE+ L + + GSK I++LL+ HH FP WL L+C+ RK+++ + R F GFRK LDDL KS+V+RD+Q YIL R+D++ L+Q ++ ET E+LN LHIKSNG +YLE VLDG+ + ++ ++ I+ IPG L GLYLW+ + LF Q F V+ I N++L++ L+++E++ ++ N +N D ++ + + L KI + + + H+S EWLLDVK CT KY C+ +GH LA+ + L+P ++ N A HL + + +G+H +WL+ S +E + G LP E+ + K+L E+ L + + + + + N ++AT L + Q + + LI G D+ +++ G T+L +AA+ G + I ++L+ + AN D +GW+ LR A W G+ EVV LLL D ++ RTALR AAW G DIVL LL G+++NK D+EGRT L+AA+Y +V+ LL +GA ++ +D DGR+A+ VAALC+ ++ L ++ LLL Y ++ D +GM +L+AAYEG +C++LLEN+AD+D D R+PL+AAA G+ +VV LLLF+GAAI ID G +VLSI+ +QGN +++ ELL RGLDE+HRDN G TPLH+A+ EG E L++ G+K NE DN GRIPL+++ QEG+++ L+ ++ +S+DG + ++A + E E L+ G D D +GR+ L++ L++ LL+ I D +GRT +H+ASW+G EI ++L++ GA ++ DN+ RT L +WQG + I +L+++FG +++ TC+QGAT+L IA+QEGH EI LL+ +GAN H D C RTP +VA KGNH +C LLE++GA Sbjct: 46 KTAVCAEMT--WPTGQGRQQALSKRILAYHFCQAHDIETLSLTNFILSLVDQISKSDLI-EGY-RDVISEPDVKAALKRETCEVNPDDAFKKGVLDPLLSIPPPSQNVFILVDSIDESYLQ--------------SINDTGTGSKTIAELLANHHQLFPTWLMLICSARKQSKSVTRLFTGFRKISLDDLRKSHVVRDVQQYILCRLDQEQGLRQHLSRETAEMLNQLHIKSNGCFLYLEKVLDGVAESFIMLREIREIPGTLNGLYLWLCQRLFVKKQ-FQKVQPILNVILAARSPLTEEELFRSVWTGNTTLNVDEFHSRMEALSKIIFSGQEGTKILF---HHSFAEWLLDVKHCTQKYLCNAAEGHGMLAMNLTLTAPHLSPEEVHNLALHLSKAHLVAPTEGFHLPLWLIQSGAPVETSLMAGGLPKEQ----------QVTKLLLEAGAELPKSAEESTSATLEKIEKQEKKKSESLKELVENGVGINEVDATG--RPLLCAAAHQGNIAMVQLLISRGADLEAMDKTGQTALNLAARQGHSEIVSILIKAQANGDHTDTEGWTPLRSAAWGGHTEVVGLLLIAGAQVDLADSENRTALRAAAWGGHEDIVLKLLEYGADVNKVDNEGRTALIAASYMGHTEIVQHLLEHGANLNQEDCDGRTALSVAALCIPASQGGLHASVVSLLLDYGAEVDHQDKDGMTPVLVAAYEGHHEVCELLLENDADVDHTDNNGRTPLLAAASMGHAKVVSLLLFFGAAIDTIDPEGRTVLSIACAQGNVEVVQELLDRGLDELHRDNAGLTPLHMAAFEGHKEVCEALIEHGSKVNETDNEGRIPLIVAAQEGHLECVRVLLAAG-SLLDHRSHDGKNAFRVAAMEGHKEVTELLIQEGTDMNYCDADGRSTLYLVALENNLVITNALLKGGADPEI-----ADFEGRTPLHVASWQGHHEICEALLNWGANVNSVDNDCRTPLQSASWQGHFSIVKLILEFGADVEHTCNQGATSLCIAAQEGHDEIVRLLLQYGANANHADQCGRTPMRVAMKGNHQGVCKLLEEYGAF 1073
BLAST of Ankyrin repeat domain 50 vs. TrEMBL
Match: A0A087T2Z3 (Ankyrin repeat domain-containing protein 50 (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_04310 PE=4 SV=1) HSP 1 Score: 728.398 bits (1879), Expect = 0.000e+0 Identity = 400/1034 (38.68%), Postives = 610/1034 (58.99%), Query Frame = 2 Query: 239 KTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSD---CDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 K L LLA HFC A DI+SL+LA FI + L S YS I S + PD AFK G+L PLL PP++ +IL+DS+D+++L +G+K N S++I++LLS +H+ FP WL L+C+ RK+++ + R F GFRK LDDL KS+V+RD+Q YIL R+D+++ L+Q ++ ET E+LN LHIKSNG +YLE VLDG+ + ++ ++ I+ IPG L GLYLW+ + LF Q F V +I N++L+S K L+++ +Y + + N + L + L++ H+S EWLLDVK CT KY C+ +GH +A+ S L+ +I +FA HL + +H +WL++ + D +K +P + VK+L + + S + + + S S+ + + L + + N + +LI G ++ +++NG + + +AA+ G I LLL++GA+ D DGW+ LR + W G+ EVV +LL D D RTALR AAW G +IV LL+ G+ +NK D+EGRT L+AA Y +V+ LL++ A I+H+D+DGR+A+ VAALC+ ++ + ++ LLL ++ D +GM LL+AA+EG +C++LLEN AD+D D R+PL+AAA G+ VVRLLLFWGAA+ ID G +VLSI+A+QG+ + +LL RGLDEMHRDN G TPLH A+ EG E LLL++GAK E+DN GRIPL+L+ QEG+ + EKL++ P V+ +++DG T+L+IA L E V+ L++ GAD +D +GR+ L++ L+++ + + LL ++ D +GRTA+H+++W+G ++++ L++ GA ++ DN+ RT L AWQG + +LL++ +D C+QGATAL IA+QEGHLE+ +L+ +GA+ H D R P +VA KG H + LLE++ A Sbjct: 62 KQSTLSKRLLAYHFCQAHDINSLSLASFINNLISQLTASPLLSG-YSDRIKSPEVEAALQLAECERNPDEAFKKGVLFPLLEIDPPSQPCFILVDSVDQSILG-AVGDK------------NGGVSRSIAELLSNYHHLFPRWLLLICSSRKQSKTVTRMFTGFRKISLDDLRKSHVVRDVQQYILCRLDQEEALRQHLSRETAEMLNQLHIKSNGCFMYLEKVLDGVGENFIMLREIREIPGTLNGLYLWLCQRLFVRKQ-FNKVLSILNVILASRKPLTEEVLYQCVWTRNTNLTWEDYQKRLRLLSKVLIEGKGGTKILFHHSFAEWLLDVKHCTQKYLCNAKEGHGMIAMRYTVASPHLSSEEIIDFALHLSKIPLTSSLQSHHITLWLIHCNLPLADCLMKTSMPKDP----------QTVKLLVSAGAKLPTGDTVKDSSPKVPDDPLEALLSVGSDINQVDSNQRTLLHRASHEGIDNLVLRLIEKGANLEAIDKNGQSPINLAARQGHALIVELLLTAGADPDHADNDGWTPLRSSAWAGHTEVVNVLLEHGAQVDLADADHRTALRAAAWGGHEEIVSRLLAHGACVNKVDNEGRTALIAAAYMGHTEIVQQLLDHDAEINHEDSDGRTALSVAALCVPASEGHARVVSLLLERGTEVDHRDKDGMTPLLVAAFEGHSEVCELLLENEADVDHTDNNGRTPLVAAASMGHPSVVRLLLFWGAAVDTIDAEGRTVLSIAAAQGDPDTVRQLLDRGLDEMHRDNGGWTPLHYAAFEGHTEACELLLEAGAKITEVDNDGRIPLILAAQEGHTNLVEKLLEHTPSMVDCRAHDGKTALRIATLEGQKETVQLLINHGADLNYKDADGRSTLYLLALENRTELAEFLLARGA-----DVEARDLEGRTALHVSAWQGHTDMVELLLNHGADVNAVDNDYRTALQSAAWQGHVSVVRLLVERSAIVDHVCNQGATALCIAAQEGHLEVVKVLLEYGADPSHADQFGRNPIRVASKGGHNHVIRLLEEYVA 1065 HSP 2 Score: 189.889 bits (481), Expect = 6.160e-45 Identity = 146/464 (31.47%), Postives = 238/464 (51.29%), Query Frame = 2 Query: 1979 DIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASV-----EGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGIN-IDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 D + LLS GS+IN+ DS RT L A+++ +V L+ GA ++ D +G+S I +AA + I++LLL + + DN+G L +A+ G + +LLE+ A +D+ D R+ L AAA+ G+ E+V LL GA ++ +D G + L +A G+++I+ +LL + H D+ G T L +A++ EG V+LLL+ G + + D G PL+++ EG+ ++ E L++ + V+ +G T L A P V LL GA D GRT L I+ Q D + LL L D+ G T +H A+++G E + L++ GA+I DN+GR L L A +G + + L++ + +D G TAL IA+ EG E LLIN GA++ + D+ R+ + N ++ L GA V+ +++ Sbjct: 488 DPLEALLSVGSDINQVDSNQRTLLHRASHEGIDNLVLRLIEKGANLEAIDKNGQSPINLAA-----RQGHALIVELLLTAGADPDHADNDGWTPLRSSAWAGHTEVVNVLLEHGAQVDLADADHRTALRAAAWGGHEEIVSRLLAHGACVNKVDNEGRTALIAAAYMGHTEIVQQLLDHDAEINHEDSDGRTALSVAALCVPASEGHARVVSLLLERGTEVDHRDKDGMTPLLVAAFEGHSEVCELLLENEAD-VDHTDNNGRTPLVAAASMGHPSVVRLLLFWGAAVDTIDAEGRTVLSIAAAQGDPDTVRQLLDRGLDEMHR-----DNGGWTPLHYAAFEGHTEACELLLEAGAKITEVDNDGRIPLILAAQEGHTNLVEKLLEHTPSMVDCRAHDGKTALRIATLEGQKETVQLLINHGADLNYKDADGRSTLYLLALENRTELAEFLLARGADVEARDL 940 HSP 3 Score: 153.68 bits (387), Expect = 8.739e-34 Identity = 99/316 (31.33%), Postives = 165/316 (52.22%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLS-SGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDN 2632 L+ G ++ ++ G T L +AA G LL G +++ D GW+ L A + G+ E +LLL NDGR L AA G T++V LL + S ++ + +G+T L AT + V+LL+N+GA ++++D DGRS +++ AL ++ + LL ++ D EG L ++A++G + ++LL + AD++ VD R+ L +AA+ G+ VVRLL+ A + + G + L I+A +G+ +++ LL G D H D FG P+ +AS G + LL + A E+ N Sbjct: 762 LLFWGAAVDTIDAEGRTVLSIAAAQGDPDTVRQLLDRGLDEMHRDNGGWTPLHYAAFEGHTEACELLLEAGAKITEVDNDGRIPLILAAQEGHTNLVEKLLEHTPSMVDCRAHDGKTALRIATLEGQKETVQLLINHGADLNYKDADGRSTLYLLAL-----ENRTELAEFLLARGADVEARDLEGRTALHVSAWQGHTDMVELLLNHGADVNAVDNDYRTALQSAAWQGHVSVVRLLVERSAIVDHVCNQGATALCIAAQEGHLEVVKVLLEYGADPSHADQFGRNPIRVASKGGHNHVIRLLEEYVAHLQEVGN 1072 HSP 4 Score: 84.7297 bits (208), Expect = 1.355e-12 Identity = 69/236 (29.24%), Postives = 113/236 (47.88%), Query Frame = 2 Query: 2639 RIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGAD----ATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDR 3334 +IPL S Q +I + W N D L + + P+ V+ L+S GA T++D++ + P D + LL ++IN +D + RT +H AS +G ++ LI+ GA ++ D G++ ++L A QG I +LL+ G + D + G T L ++ GH E+ N+L+ GA V D+ RT + A G H +I + L HGA V++ Sbjct: 423 KIPLTSSLQSHHITL-------WLIHCNLPLAD---CLMKTSMPKDPQTVKLLVSAGAKLPTGDTVKDSSPKVP---------DDPLEALLSVG-----SDINQVDSNQRTLLHRASHEGIDNLVLRLIEKGANLEAIDKNGQSPINLAARQGHALIVELLLTAGADPDHADNDGWTPLRSSAWAGHTEVVNVLLEHGAQVDLADADHRTALRAAAWGGHEEIVSRLLAHGACVNK 634
BLAST of Ankyrin repeat domain 50 vs. TrEMBL
Match: L7MGU2 (ANK_REP_REGION domain-containing protein (Fragment) OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1) HSP 1 Score: 715.687 bits (1846), Expect = 0.000e+0 Identity = 383/1054 (36.34%), Postives = 598/1054 (56.74%), Query Frame = 2 Query: 251 LKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYS-----RNINSSGLCNLFLSQNLC-NYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLL-----SDYLGEKLSYIF------NKDTFHK----NRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINS-ETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFES-INLVNINKLNAKKSFTIFSTYI---LNITSTYSNSIEATNVYSFSLFESIR-QNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVW---PESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEK 3313 L LLA HFC A D +L +A F+ + + L + + G + R+ +S L C +PD AFK +L PLL PP + +L+DS+DE+LL S G + + H +GS+ I++LL+AH FP+WL LVC+ R++++ I R F GFRK LDDL K+ V+RD+Q YIL R+D ++ L+Q + + +T E LN LHIKSNG ++YLE +LDG+ +++++ I+HIPG L GLYLW+ + LF+ Q F+ V+ + +++L++ + L+ +E++ L + L + LV+ D C H+S EWLLDVK CT KY C +GH LA+ +L P Q+++ A HL+ P + H +WLLYS +E C GS+ ++++L E+ L + + + + + L+ S++ + +L + + + +L+ + + NG T L +AA+ G + LLL +GAN D +GW+ LR + W G+ +VV+ LL K D + RTALR A+W G ++V LL G+++N+ D EGRT L+AA Y +V+ LL+ GA +H D DGR+A+ VAALC+ + +L ++ LLL +++ +DNEGM LL+AA+EG + +C++LL+ AD+D D R+PL AAA G+ +VV LLLFWGA + ID G +VLSI+A+QG+ +++ +LL RGLDE+HRDN G TPLH A++EG E LL+++GA+ +E DN GR PL+L+ QEG+ + ++D P V+ +++DG T+ ++A L E V LLS AD QD +GR+ L++ L+ + D +L I ++ +GRT +H+A+W+G ++++ L+ GA +D +D++ RT L AWQG + +LL++ G +D C +GATAL IASQEGH + L+ GA+ H D C R+P +VA K H+ + LLE+ Sbjct: 114 LSRRLLAHHFCQAHDTRTLAVASFVLGLVRQLCRCEQAGLLSGYQDRLRDAEAS------LEPVACARWPDEAFKKAVLFPLLEIEPPEQPCLLLVDSVDESLLVQVNASGVTGSHQHHRHHHHHHDGGERRHHCLPDGGRGSRTIAELLAAHQQLFPQWLLLVCSARRQSKTITRMFTGFRKISLDDLRKASVVRDMQQYILARLDGEEALRQQLGARDTAEALNQLHIKSNGCLLYLECLLDGVAQRWVTLREIRHIPGTLNGLYLWLCQRLFQRRQ-FLRVQPVLHVLLAAAQPLTAEELFLCLWTRNQLLTHDEFGRRLALLSRLLVEREDGCLLLFHHSFAEWLLDVKHCTQKYLCHAAEGHAMLAMMQTLRGPQLPPTQVQDLAHHLLRLPPCDAVEPQHLTLWLLYSGVPLECAF---CPTVGSVVIPRDPAVLRLLLEAGARLPTASVAGSDEGGSPVPSMPPDPLDALLGSGASVDDADANQRALLHTAAYEGDAALVERLLHAKASLELADRNGQTPLNLAARQGHADVVVLLLKAGANPDHADNEGWTPLRSSAWAGHGQVVEALLENKAQVDLADGEQRTALRAASWGGHEEVVAQLLEKGADVNRADREGRTALIAAAYMGHAEIVERLLDAGAEANHADGDGRTALSVAALCVRPSEGHLGVVALLLERGADVDHVDNEGMTPLLVAAFEGHREVCELLLDAEADLDHADHSGRTPLFAAASMGHADVVGLLLFWGAYVDSIDAEGRTVLSIAAAQGSVEVVQQLLNRGLDELHRDNAGWTPLHYAALEGHAEVCTLLMEAGAQASETDNEGRTPLILAAQEGHTQAVRAMLDFGGHPPSLVDHRAHDGRTAFRVAALEGHKETVHVLLSYNADVNYQDADGRSTLYVLALEGRVDMADYILARGADPEIGDL-----EGRTPLHVAAWQGHVDLVELLLSRGADVDAEDSDQRTALQSAAWQGQAHVVKLLLERGAQVDHICVEGATALGIASQEGHEAVVRALLEHGADPSHADQCGRSPLRVATKAGHLNVVRLLEE 1152 HSP 2 Score: 154.451 bits (389), Expect = 5.481e-34 Identity = 102/326 (31.29%), Postives = 160/326 (49.08%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSN----INKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKS 2605 LF + + + L+ G ++ ++ G T L +AA G + LL+ G ++L D GW+ L A G+ EV LL+ T N+GRT L AA G T V +L G + ++ + +GRT A + V +LL+ A +++QD DGRS ++V AL +D+ +L + + D EG L +AA++G L ++LL AD+D D R+ L +AA+ G VV+LLL GA + I G + L I++ +G+ ++ LL G D H D G +PL +A+ G V LL +S Sbjct: 833 PLFAAASMGHADVVGLLLFWGAYVDSIDAEGRTVLSIAAAQGSVEVVQQLLNRGLDELHRDNAGWTPLHYAALEGHAEVCTLLMEAGAQASETDNEGRTPLILAAQEGHTQAVRAMLDFGGHPPSLVDHRAHDGRTAFRVAALEGHKETVHVLLSYNADVNYQDADGRSTLYVLAL-----EGRVDMADYILARGADPEIGDLEGRTPLHVAAWQGHVDLVELLLSRGADVDAEDSDQRTALQSAAWQGQAHVVKLLLERGAQVDHICVEGATALGIASQEGHEAVVRALLEHGADPSHADQCGRSPLRVATKAGHLNVVRLLEES 1153 HSP 3 Score: 72.0182 bits (175), Expect = 1.064e-8 Identity = 53/193 (27.46%), Postives = 86/193 (44.56%), Query Frame = 2 Query: 2762 VLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 V+ R P + LL GA G V D LL + ++ D + R +H A+++GD +++ L+ A ++L D G+T L+L A QG + LL+ G N D ++G T L ++ GH ++ L+ A V D RT + A G H ++ L + GA V+R + Sbjct: 536 VIPRDPAVLRLLLEAGARLPTASVAGSDEGGSPVPSMPPDPLDALLGSGAS-----VDDADANQRALLHTAAYEGDAALVERLLHAKASLELADRNGQTPLNLAARQGHADVVVLLLKAGANPDHADNEGWTPLRSSAWAGHGQVVEALLENKAQVDLADGEQRTALRAASWGGHEEVVAQLLEKGADVNRAD 723
BLAST of Ankyrin repeat domain 50 vs. TrEMBL
Match: A0A131YW74 (Ankyrin repeat domain-containing protein 50 OS=Rhipicephalus appendiculatus OX=34631 PE=4 SV=1) HSP 1 Score: 714.146 bits (1842), Expect = 0.000e+0 Identity = 383/1055 (36.30%), Postives = 598/1055 (56.68%), Query Frame = 2 Query: 251 LKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYS-----RNINSSGLCNLFLSQNLC-NYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLL-----SDYLGEKLSYIF--------NKDTFH---KNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINS-ETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFES-INLVNINKLNAKKSFTIFSTYI---LNITSTYSNSIEATNVYSFSLFESIR-QNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVW---PESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEK 3313 L LLA HFC A D +L +A F+ + + L + + G + R+ +S L C +PD AFK +L PLL PP + +L+DS+DE+LL S G + + H +GS+ I++LL+AH FP+WL LVC+ R++++ I R F GFRK LDDL K+ V+RD+Q YIL R+D ++ L+Q + + +T E LN LHIKSNG ++YLE +LDG+ +++++ I+HIPG L GLYLW+ + LF+ Q F+ V+ + +++L++ + L+ +E++ L + L + LV+ D C H+S EWLLDVK CT KY C +GH LA+ +L P Q+++ A HL+ P + H +WLLYS +E C GS+ ++++L E+ L + + + + + L+ S++ + +L + + + +L+ + + NG T L +AA+ G + LLL +GAN D +GW+ LR + W G+ +VV+ LL K D + RTALR A+W G ++V LL G+++N+ D EGRT L+AA Y +V+ LL+ GA +H D DGR+A+ VAALC+ + +L ++ LLL +++ +DNEGM LL+AA+EG + +C++LL+ AD+D D R+PL AAA G+ +VV LLLFWGA + ID G +VLSI+A+QG+ +++ +LL RGLDE+HRDN G TPLH A++EG E LL+++GA+ +E DN GR PL+L+ QEG+ + ++D P V+ +++DG T+ ++A L E V LLS AD QD +GR+ L++ L+ + D +L I ++ +GRT +H+A+W+G ++++ L+ GA +D +D++ RT L AWQG + +LL++ G +D C +GATAL IASQEGH + L+ GA+ H D C R+P +VA K H+ + LLE+ Sbjct: 81 LSRRLLAHHFCQAHDTRTLAVASFVLGLVRQLCRCEQAGLLSGYQDRLRDAEAS------LEPVACARWPDEAFKKAVLFPLLEIEPPEQPCLLLVDSVDESLLVQVNTSGVTGSHQHHRHHHHHHHDGGERRHHCLPDGGRGSRTIAELLAAHQQLFPQWLLLVCSARRQSKTITRMFTGFRKISLDDLRKASVVRDMQQYILARLDGEEALRQQLGARDTAEALNQLHIKSNGCLLYLECLLDGVAQRWVTLREIRHIPGTLNGLYLWLCQRLFQRRQ-FLRVQPVLHVLLAAAQPLTAEELFLCLWTRNQLLTHDEFGRRLALLSRLLVEREDGCLLLFHHSFAEWLLDVKHCTQKYLCHAAEGHAMLAMMQTLRGPQLPPTQVQDLAHHLLRLPPCDAVEPQHLTLWLLYSGVPLECAF---CPTVGSVVIPRDPAVLRLLLEAGARLPTASVAGSDEGGSPVPSMPPDPLDALLGSGASVDDADANQRALLHTAAYEGDAALVERLLHAKASLELADRNGQTPLNLAARQGHADVVVLLLKAGANPDHADNEGWTPLRSSAWAGHGQVVEALLENKAQVDLADGEQRTALRAASWGGHEEVVAQLLEKGADVNRADREGRTALIAAAYMGHAEIVERLLDAGAEANHADGDGRTALSVAALCVRPSEGHLGVVALLLERGADVDHVDNEGMTPLLVAAFEGHREVCELLLDAEADLDHADHSGRTPLFAAASMGHADVVGLLLFWGAYVDSIDAEGRTVLSIAAAQGSVEVVQQLLNRGLDELHRDNAGWTPLHYAALEGHAEVCTLLMEAGAQASETDNEGRTPLILAAQEGHTQAVRAMLDFGGHPPSLVDHRAHDGRTAFRVAALEGHKETVHVLLSYNADVNYQDADGRSTLYVLALEGRVDMADYILARGADPEIGDL-----EGRTPLHVAAWQGHVDLVELLLSRGADVDAEDSDQRTALQSAAWQGQAHVVKLLLERGAQVDHICVEGATALGIASQEGHEAVVRALLEHGADPSHADQCGRSPLRVATKAGHLNVVRLLEE 1120 HSP 2 Score: 154.066 bits (388), Expect = 6.447e-34 Identity = 102/326 (31.29%), Postives = 160/326 (49.08%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSN----INKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKS 2605 LF + + + L+ G ++ ++ G T L +AA G + LL+ G ++L D GW+ L A G+ EV LL+ T N+GRT L AA G T V +L G + ++ + +GRT A + V +LL+ A +++QD DGRS ++V AL +D+ +L + + D EG L +AA++G L ++LL AD+D D R+ L +AA+ G VV+LLL GA + I G + L I++ +G+ ++ LL G D H D G +PL +A+ G V LL +S Sbjct: 801 PLFAAASMGHADVVGLLLFWGAYVDSIDAEGRTVLSIAAAQGSVEVVQQLLNRGLDELHRDNAGWTPLHYAALEGHAEVCTLLMEAGAQASETDNEGRTPLILAAQEGHTQAVRAMLDFGGHPPSLVDHRAHDGRTAFRVAALEGHKETVHVLLSYNADVNYQDADGRSTLYVLAL-----EGRVDMADYILARGADPEIGDLEGRTPLHVAAWQGHVDLVELLLSRGADVDAEDSDQRTALQSAAWQGQAHVVKLLLERGAQVDHICVEGATALGIASQEGHEAVVRALLEHGADPSHADQCGRSPLRVATKAGHLNVVRLLEES 1121 HSP 3 Score: 72.0182 bits (175), Expect = 9.543e-9 Identity = 53/193 (27.46%), Postives = 86/193 (44.56%), Query Frame = 2 Query: 2762 VLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 V+ R P + LL GA G V D LL + ++ D + R +H A+++GD +++ L+ A ++L D G+T L+L A QG + LL+ G N D ++G T L ++ GH ++ L+ A V D RT + A G H ++ L + GA V+R + Sbjct: 504 VIPRDPAVLRLLLEAGARLPTASVAGSDEGGSPVPSMPPDPLDALLGSGAS-----VDDADANQRALLHTAAYEGDAALVERLLHAKASLELADRNGQTPLNLAARQGHADVVVLLLKAGANPDHADNEGWTPLRSSAWAGHGQVVEALLENKAQVDLADGEQRTALRAASWGGHEEVVAQLLEKGADVNRAD 691
BLAST of Ankyrin repeat domain 50 vs. TrEMBL
Match: A0A1S3FLW4 (ankyrin repeat domain-containing protein 50 OS=Dipodomys ordii OX=10020 GN=Ankrd50 PE=4 SV=1) HSP 1 Score: 712.99 bits (1839), Expect = 0.000e+0 Identity = 393/1036 (37.93%), Postives = 601/1036 (58.01%), Query Frame = 2 Query: 266 LASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDI--EVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNA--------KKSFTIFS----TYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 LA HFC A D D+L + FI + + +S + Y + + +L P AFK +LLPLL PP +++Y+L+DS+DE + GE+ S S +++LL+ HH+FFP WL L+C+ RK+++ + + F GFRK LDDL K+Y+++D+Q YIL+R+D+++ L+Q + ET E+LN LHIKS+G +YLE VLDG+++ ++ ++ I+ IPG L GLYLW+ + LF Q F V+ I N++L++ + L+ E+Y A+ +++ L + L + LV N H S EWLLDVK CT KY C+ +GH LA+ + L PL+ + FA HLI S + + A+W++++ + + ++P E+ +++++L ++ VN A ++ +I + +N + ++ A YS +L + ++ L+ G D+ + +G T L +AA+ G T + N L+ GAN D+DGW+ALR A W G+ EVV LL + D D RTALR AAW G DIVL LL G+ +NK D+EGRT L+AA Y +V+ LL++GA +DH+D DGR+A+ VAALC+ ++ + ++ LL+ ++ D +GM LL+AAYEG + +LLE AD+D D R+PL+AAA G+ VV LLFWGAA+ ID G +VLSI+++QGN +++ LL RGLDE HRD+ G TPLH+A+ EG L++ GA+ NE DN GRIP +L+ QEG+ + L++ +V+ + YDG +L++A L + VE LLS GAD +D +GR L+I L++Q + L+ N N+ D +GRTA+H++ W+G E+++ LI A ++ DNE R+ L AWQG ++CQLLI+ G +D TC+QGATAL IA+QEGH+++ +L+ A+ H D RT +VA K H +I LLEK+GA Sbjct: 108 LAFHFCKAQDSDTLCVGGFIRGLVAQICRSGLL-QGYEDKLRDPAVQSLLQPGECERNPAEAFKRCVLLPLLGMKPPQQSLYLLVDSVDEGW-NIAEGEQTSSSL-----------SGTVAELLAGHHDFFPPWLLLLCSARKQSKAVTKMFTGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAEMLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQ-FAKVQPILNVILAACRPLTVTELYHAVWTKNMSLTLEDFQRKLDVLSKLLVDGLGNTKILFHYSFAEWLLDVKHCTQKYLCNAAEGHRMLAMSYTCRAKNLTPLEAQEFALHLIHSN--LQLEPAELALWMIWNGTPVGDSLSTLIPKEQ----------EVLQLLVKAGAHVNSEDERASCIVRQALEREDSIRTLLDNGASVNQCDSSGRTLLANAAYSGNL---------DVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGRGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAKVDHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDHNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNETDNDGRIPFILASQEGHYDCVQILLES-KSNVDQRGYDGRNALRVAALEGHRDIVELLLSHGADVDYKDADGRPTLYILALENQLTMAEYFLE-----NGANVEASDAEGRTALHVSCWQGHVEMVQVLIACHADVNAADNEKRSALQSAAWQGHVRVCQLLIEHGAQVDHTCNQGATALCIAAQEGHVDVVQVLLEHAADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGA 1102 HSP 2 Score: 250.366 bits (638), Expect = 7.403e-64 Identity = 169/520 (32.50%), Postives = 274/520 (52.69%), Query Frame = 2 Query: 1796 LLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAF-----SGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 LL +GA+ D G + L A ++G ++VV LL+S+ D + G T L AA G T +V L+ G+NIN D +G T L +A + +V LL G +D D D R+A+ AA + DI+ LL++ +N DNEG L+ AAY G + + + LL++ A +D D R+ L AA G+ VV LL+ GA + DK G + L ++A +G+ ++ LL G D H D+ G TPL A+ G VN LL GA + ID+ GR L ++ +G +++ L+D + N + G T L +A E L+ +GA DN+GR P ++ + YDC Q+LL+ + +N++ DGR A+ +A+ +G +I++ L+ GA +D KD +GR L++ A + + + ++ G N++ + ++G TAL ++ +GH+E+ +LI A+V D+ R+ + A H+++C LL +HGA VD Sbjct: 531 LLDNGASVNQCDSSGRTLLANAAYSGNLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGRGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAW-----GGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAKVDHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDHNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE-NHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNETDNDGRIPFILASQEGHYDCVQILLE-----SKSNVDQRGYDGRNALRVAALEGHRDIVELLLSHGADVDYKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHVEMVQVLIACHADVNAADNEKRSALQSAAWQGHVRVCQLLIEHGAQVD 1039 HSP 3 Score: 196.823 bits (499), Expect = 3.875e-47 Identity = 144/463 (31.10%), Postives = 229/463 (49.46%), Query Frame = 2 Query: 1979 DIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSC-----QEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +++ LL+ +G+++N +D + A + D + + LL+NGA ++ D+ GR+ + AA N LD++ LL+ ++ + D G L +AA +G + L+ A+I+ D+ + L +AA+ G+ EVV LL+ G + C D + L +A G+ I+ LL G + DN G T L A+ G E V LL GAK + D GR L ++ +G+ + LID E V+ DG T L +A + V+ LL GAD D+NGRTPL + LL ++ +D +GRT + IAS +G+ E++++L+D G + +D+ G T LH+ A++G IC+ LI+ G +ET + G +ASQEGH + +L+ +NV R +VA H I LL HGA VD K+ Sbjct: 495 EVLQLLVKAGAHVNSEDERASCIVRQALEREDSI--RTLLDNGASVNQCDSSGRTLLANAAYSGN-----LDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGRGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAKVDHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAE-VDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDHNGRTPLLAAASMGHASVVNTLLFWGAA-----VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNETDNDGRIPFILASQEGHYDCVQILLESKSNVDQRGYDGRNALRVAALEGHRDIVELLLSHGADVDYKDA 944 HSP 4 Score: 150.599 bits (379), Expect = 8.801e-33 Identity = 104/365 (28.49%), Postives = 187/365 (51.23%), Query Frame = 2 Query: 1499 DIVKILFESINLVNINKLNAKKSF----TIFSTYILNITSTYSNSIEATNVYSFSLFE-SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVE 2569 D+V +L E V+ N + ++ ++N + ++++ + ++ + Q + + L+ GLD N ++ G T L +AA G IC L+ GA D DG LA G+ + V++LL K + D G DGR ALR AA G DIV LLLS G++++ +D++GR L + M + L NGA ++ D +GR+A+ V+ C +++++++L+ + ++N DNE + L AA++G +C++L+E+ A +D + L AA G+ +VV++LL A + D+ G + + ++A G+SQI+ L G ++ GC+P + ++E Sbjct: 762 DVVDLLLEGGADVDHTDHNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNETDNDGRIPFILASQEGHYDCVQILLESKSNVDQRGYDGRNALRVAALEGHRDIVELLLSHGADVDYKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVS--CWQG---HVEMVQVLIACHADVNAADNEKRSALQSAAWQGHVRVCQLLIEHGAQVDHTCNQGATALCIAAQEGHVDVVQVLLEHAADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASTLN----GCSPSPVHTME 1117
BLAST of Ankyrin repeat domain 50 vs. Ensembl Cavefish
Match: ANKRD50 (ankyrin repeat domain 50 [Source:NCBI gene;Acc:103026486]) HSP 1 Score: 686.411 bits (1770), Expect = 0.000e+0 Identity = 391/1046 (37.38%), Postives = 602/1046 (57.55%), Query Frame = 2 Query: 245 QKLKSLLLASHFCSASDIDSLNLAKFI----FEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNY-PDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVN----------INKLNAKKSFTIF--STYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 + L L LA HFC A D D++ L+ F+ +I L +Y +I + S+ L C P AFK +LLPLLS PP + +++L+DS+DE + + GE S + ++I +LL+AHH P WL L+C+ R++N+ I + F GFRK LDDL K+Y+++D+Q YIL+R+D+++ L+Q + ET E+LN LHIKS+G +YLE VLDG+++ ++ ++ I+ IPG L GLYLW+ + LF Q F V+ I NI+L++ + L+ +E+Y A+ ++ + + + + LV H S EWLLDVK CT KY C+ +GH +A+ + +L PL+++ FA HLI S + + ++ A+W++++ P + S + +++++L ++ +N L + S + +N + + ++ YS +L + ++ LI G ++ + +G T L +AA+ G T + N L+ +N D DGW+ALR A W G+ EVV LL D D RTALR AAW G DIVL LL G+ +NK D+EGRT L+AA Y +V+ LL++GA ++H+D DGR+A+ VAALC+ ++ + ++ LL+ ++ D + M LL+AAYEG + +LLE AD+D D R+PL+AAA G+ VV LLFWGAA+ ID G +VLSI+++QGN +++ LL RGLDE HRD+ G TPLH+A+ EG + + LL+ GA+ +E+DN GRIPL+L+ QEG+ + L++ ++ + YDG SL++A L + VE LLS GAD D +GR L+I L++Q + L+ N N+ D +GRTA+H++ W+G E+++ LI A ++ DNE R+ L AWQG ++ Q LID G ++D TC+QGATAL IA+QEGH+++ +L+ GA+ H D RT +VA KG H I LLEK+GA Sbjct: 94 RGLHQLCLAFHFCRAEDADTVCLSGFVRGLVAQIRAGGLVPQYEEKIRDPAVQSA------LQPGECERNPSEAFKRCVLLPLLSCKPPPQALFLLVDSVDEGVKAAE-GESRSSASS----------PRSIGELLAAHHELLPPWLLLICSGRRQNKNITKLFTGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAEMLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQ-FAKVQPILNIILAACRPLTVKELYHAVWTKNMTLTMEEFQKKMDILTKLLVDGLGGTKILFHYSFAEWLLDVKHCTQKYLCNAAEGHRMMAMSYTCRAKQLKPLEVQEFALHLINSN--LQIEPFNLALWMVWNGT--------PAKDSLSTSIPKEQEVLQLLVKAGAHINNEDDHASCIVQQALEREDSIRTLLDNGASVNQSDSSGRTLLGNAAYSGNL---------DVVNLLISRGANMELQDNHGQTPLTLAARQGHTKVVNCLIGCDSNINHTDHDGWTALRSAAWGGHSEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDCMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRQVCDALLEQGARCSEVDNDGRIPLILAAQEGHYDCVQILLEN-KSCIDQRGYDGRNSLRVAALEGHRDIVELLLSHGADIDYNDADGRPTLYILALENQLAMAEYFLE-----NGANVETSDTEGRTALHVSCWQGHVEMVRLLISYHADVNSCDNEKRSALQSAAWQGHSKVVQFLIDSGTHVDHTCNQGATALGIAAQEGHIDVVRILLEHGADPNHADQFGRTAMRVAAKGGHSGIIKLLEKYGA 1096 HSP 2 Score: 243.047 bits (619), Expect = 4.797e-65 Identity = 177/556 (31.83%), Postives = 285/556 (51.26%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAF-----SGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDD---DGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 L+ G IN NE+ S +V LL +GA+ D G + L A ++G ++VV LL+S+ + + N G+T L AA G T +V L+ SNIN D +G T L +A + +V LL GA +D D D R+A+ AA + DI+ LL++ +N DNEG L+ AAY G + + + LL++ A++ D+ R+ L AA G+ VV LL+ GA + DK + L ++A +G+ ++ LL G D H DN G TPL A+ G VN LL GA + ID+ GR L ++ +G +++ L+D + N + G T L +A + + LL +GA + DN+GR PL ++ + YDC Q+LL+ N +C+D DGR ++ +A+ +G +I++ L+ GA ID D +GR L++ A + + + ++ G N++ + ++G TAL ++ +GH+E+ LLI++ A+V D+ R+ + A H K+ L G VD Sbjct: 494 LVKAGAHIN--NEDDHASCIVQQALEREDSIRTLLDNGASVNQSDSSGRTLLGNAAYSGNLDVVNLLISRGANMELQDNHGQTPLTLAARQGHTKVVNCLIGCDSNINHTDHDGWTALRSAAWGGHSEVVSALLYAGAKVDCADADSRTALRAAAW-----GGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDCMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE-NHRDDAGWTPLHMAAFEGHRQVCDALLEQGARCSEVDNDGRIPLILAAQEGHYDCVQILLE--------NKSCIDQRGYDGRNSLRVAALEGHRDIVELLLSHGADIDYNDADGRPTLYILALENQLAMAEYFLENGANVETSDTEGRTALHVSCWQGHVEMVRLLISYHADVNSCDNEKRSALQSAAWQGHSKVVQFLIDSGTHVD 1033 HSP 3 Score: 169.474 bits (428), Expect = 4.745e-42 Identity = 126/428 (29.44%), Postives = 222/428 (51.87%), Query Frame = 2 Query: 2081 MVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVL-----NRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 +++LL+ GA+I+++D D S I AL + D I+ LL ++N D+ G +L AAY G+ + +L+ A++++ D ++PL AA G+ +VV L+ + I+ D G++ L +A G+S+++S LL G D T L A+ G + V LL+ GA+ N+ DN GR L+ + G+ +I E L+D E VN + DG T+L +A L V L+ RGA+ D + TPL ++ + D +LL+ +++ D++GRT + A+ G ++ +L+ GA +D D+EGRT L + + QG ++ + L+D G++ + G T L +A+ EGH ++C+ L+ GA +D+ R P +A + H +L ++ + +D++ Sbjct: 490 VLQLLVKAGAHINNED-DHASCIVQQAL------EREDSIRTLLDNGASVNQSDSSGRTLLGNAAYSGNLDVVNLLISRGANMELQDNHGQTPLTLAARQGHTKVVNCLIGCDSNINHTDHDGWTALRSAAWGGHSEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAE-VNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDCMTPLLVAAYEGHVDVVDLLLEGGA-----DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRQVCDALLEQGARCSEVDNDGRIPLILAAQEGHYDCVQILLENKSCIDQRG 904 HSP 4 Score: 149.828 bits (377), Expect = 4.938e-36 Identity = 105/365 (28.77%), Postives = 185/365 (50.68%), Query Frame = 2 Query: 1499 DIVKILFESINLVNINKLNAKKSF----TIFSTYILNITSTYSNSIEATNVYSFSLFE-SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVE 2569 D+V +L E V+ N + ++ ++N + ++++ + ++ + Q + + L+ GLD N ++ G T L +AA G +C+ LL GA +D DG L LA G+ + V++LL K D G DGR +LR AA G DIV LLLS G++I+ D++GR L + M + L NGA ++ D +GR+A+ V+ C ++++++LL+ Y+ ++N DNE + L AA++G + + L+++ +D + L AA G+ +VVR+LL GA + D+ G + + ++A G+S I+ L G ++ GC P + ++E Sbjct: 756 DVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRQVCDALLEQGARCSEVDNDGRIPLILAAQEGHYDCVQILLENKSCIDQRGYDGRNSLRVAALEGHRDIVELLLSHGADIDYNDADGRPTLYILALENQLAMAEYFLENGANVETSDTEGRTALHVS--CWQG---HVEMVRLLISYHADVNSCDNEKRSALQSAAWQGHSKVVQFLIDSGTHVDHTCNQGATALGIAAQEGHIDVVRILLEHGADPNHADQFGRTAMRVAAKGGHSGIIKLLEKYGASSLN----GCNPSPIHTME 1111 HSP 5 Score: 119.013 bits (297), Expect = 1.649e-26 Identity = 92/296 (31.08%), Postives = 141/296 (47.64%), Query Frame = 2 Query: 2561 SVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQ-EGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINN------------------------------INCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIA-----SQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 S+ + E + LL+K+GA N D+H + + + E I+ L+D SVN G T L A + + V L+SRGA+ +QDN+G+TPL ++ Q L+ NIN+ ++C D D RTA+ A+W G +I+ +L+ GA ++ DNEGRT L A+ G +I + L+D G ++ G TALS+A + +GH + +LLI+ GA V H D TP VA H+ + +LL + GA VD + Sbjct: 483 SIPKEQEVLQLLVKAGAHINNEDDHASCIVQQALEREDSIRT---LLDNG-ASVNQSDSSGRTLLGNAAYSGNLDVVNLLISRGANMELQDNHGQTPLTLAARQGHTKVVNCLI--GCDSNINHTDHDGWTALRSAAWGGHSEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDCMTPLLVAAYEGHVDVVDLLLEGGADVDHTD 772 HSP 6 Score: 71.2478 bits (173), Expect = 6.425e-12 Identity = 53/186 (28.49%), Postives = 86/186 (46.24%), Query Frame = 2 Query: 2786 VEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 + LL GA D++GRT L + D +L+ N+ D+ G+T + +A+ +G +++ LI + I+ D++G T L AW G ++ L+ G +D + TAL A+ GH +I L+ GA V D+ RT A H +I L HGA V+ ++V Sbjct: 522 IRTLLDNGASVNQSDSSGRTLLGNAAYSGNLDVVNLLISRGA-----NMELQDNHGQTPLTLAARQGHTKVVNCLIGCDSNINHTDHDGWTALRSAAWGGHSEVVSALLYAGAKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDV 702 HSP 7 Score: 63.1586 bits (152), Expect = 2.038e-9 Identity = 56/209 (26.79%), Postives = 94/209 (44.98%), Query Frame = 2 Query: 1499 DIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTY----SNSIEATNVYS-FSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSG-SNINK------QDSEGRTPLMAATYKCDYVMVK 2089 DIV++L ++ N + + + I + + Y ++E ++ +L S Q + LI D+N + ++L AA G + + L+ SG + G +AL +A G+I+VV++LL DP+ GRTA+R AA G + I+ LL G S++N E +TPL A T K + +K Sbjct: 921 DIVELLLSHGADIDYNDADGRPTLYILALENQLAMAEYFLENGANVETSDTEGRTALHVSCWQGHVEMVRLLISYHADVNSCDNEKRSALQSAAWQGHSKVVQFLIDSGTHVDHTCNQGATALGIAAQEGHIDVVRILLEHGADPNHADQFGRTAMRVAAKGGHSGIIKLLEKYGASSLNGCNPSPIHTMEQKTPL-AVTGKMQSLTIK 1128
BLAST of Ankyrin repeat domain 50 vs. Ensembl Cavefish
Match: ankrd50l (ankyrin repeat domain-containing protein 50-like [Source:NCBI gene;Acc:103038240]) HSP 1 Score: 599.742 bits (1545), Expect = 0.000e+0 Identity = 367/1091 (33.64%), Postives = 577/1091 (52.89%), Query Frame = 2 Query: 188 KSTICRLLTTELTIDCFKTQK---LKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSI--DDIVKILFES----------------INLVNINKLNAKKSFTIFSTYILNITSTYS-NSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLM-----------IDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS---KYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID------IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSG--AKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDF-GINIDETC-SQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 K+ +C TEL +T K L S LA H+C D ++ + +F+ + + L S YS + S + + PD FK +L PLLS P P + +YI++DS++ +G S +I++LL H FP W+ LVC+ R++N+ + + F GFRK LDDL K +RD+Q YIL R+D++ L++ + ET ++LNLLHIKS G ++LE VLDG+ G + ++ I+ IPG L GLYLW+ + LF + F+ V+ + NI+L+S + L+ +++Y A D + ++ + +V+ + H S EW+ DVK CT K+ CS+ DGH++LA+ + S L+ I HL++S I A+W++++ V + C K S + D++++L +S I+ V + +++ + + S S N + ++ + L + + ++ L+ G D + + G T+L + A+ G + +LL +Q D DGW+ALR A W G+ E VK+LL D D DGRTALR AAW G ++++ LL G+ ++ D EGRTPL+AA Y V+++L+ GA +D D DGR+A+ VAALC+ S + + +++ LLL + D +GM LL+A+YEG + + ++LLE AD+D +PL+AAA G+ V +LFWGAA+ ID G + L ++A++G+ +++ LL RGLDE H+D+ G TPLH A+ +G +L + G A+ E+D GR L+L+ QEG+ L+D ++ +SYDG ++L A L E VE LL RGAD ++D GR L++ +L+ + D +L++ + D +GRTA+H+A+W+GD + I L+ GA + D EGR LH AW+G +L + IN+D+ C QGATALSIA+QEGH+EI +L+ GA+ H+D RTP KVA K I LLE +GA Sbjct: 57 KTALC----TELVWPQSETGKALGLASRCLAWHYCQQEDAGTMEVWRFVLGLVEQLRDSPLLAPSYSHLLASPAIAASLEPIHCQRDPDDTFKRAVLEPLLSLPSPAQAVYIVVDSLNAGY-GGCVGATEGVTSGSMAIQ-----STSIAELLLRHLQLFPPWILLVCSARRQNKAVCKMFSGFRKLCLDDLRKPAAVRDVQHYILRRLDQEGALRRQLTPETADMLNLLHIKSGGCFLFLEQVLDGVACGLVGLREIRDIPGTLNGLYLWLCQRLFPR-RLFVHVRPLLNILLASPRPLTPEKLYFAAYARDNCLGHEDFQSLMRALAPLIVEGPEGSKLLFHGSFAEWITDVKYCTQKFLCSVKDGHLSLAMSLSLRSKTLSTEDICQLGHHLLSSG-IHAGDPSLLALWMIWTG----VPTLTFCTKVSSQQIPVLVQQDVLQLLMKSGVYPPTCSPDNGPSVGIHCVGGRRGIVRRALQREDSVRALLDSGVSVNRTDPSDGRTL-LSTAAHAGLVDIVALLLCRGADPSLSDHQGQTALTLVARQGHIGVLQILLEWAQDQGTDTPAVQALLEHADSDGWTALRSAAWGGHNEAVKMLLEAGADVDGCDPDGRTALRAAAWGGHEEVLMTLLEHGAKVDCMDHEGRTPLIAAAYMGHKEAVEIILDAGAEVDLADGDGRTALSVAALCVPSATGGRGHREVVSLLLERSAEPEHKDKDGMTPLLLASYEGHEEVVELLLEAGADVDEGTGAYPSAVTPLLAAAAMGHAGTVNRMLFWGAAVDGIDGEGRTALCLAAAKGSVEVVKALLDRGLDENHKDDLGWTPLHAAACDGHKSVCAVLTERGSMARVGELDVEGRTALILAAQEGHCSTVRLLLDR-KSPIDHRSYDGHSALSAASLQGHTEVVELLLRRGADTDVRDAEGRPLLYLLILEGRLDIATLLIEKGGV----PLESRDAEGRTALHVAAWQGDLDGIGLLLGHGADPNALDQEGRPPLHSVAWRGLTSAGRLFLRARDINVDQACKKQGATALSIAAQEGHVEIVAMLLEKGADPDHVDHYGRTPVKVAGKRGLFNIIRLLESYGA 1125 HSP 2 Score: 151.369 bits (381), Expect = 1.772e-36 Identity = 129/450 (28.67%), Postives = 213/450 (47.33%), Query Frame = 2 Query: 2084 VKLLLNNGAYIDHQD-NDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLE----NNADIDIVDR----------SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSC--------QEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNI-----NNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFG--INIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 V+ LL++G ++ D +DGR+ + AA ++ +DI+ LLL + +L D++G L + A +G + +ILLE D V + L +AA+ G+ E V++LL GA + D G + L +A G+ ++L LL G D+ G TPL A+ G E V ++L +GA+ + D GR L ++ G+ ++ L++ E K DG T L +A E VE LL GAD + + G P ++ L + + H+ T N ++ +D +GRTA+ +A+ KG E++K+L+D G + KD+ G T LH A G +C +L + G + E +G TAL +A+QEGH LL++ + + H + A H ++ LL + GA D ++ Sbjct: 528 VRALLDSGVSVNRTDPSDGRTLLSTAA-----HAGLVDIVALLLCRGADPSLSDHQGQTALTLVARQGHIGVLQILLEWAQDQGTDTPAVQALLEHADSDGWTALRSAAWGGHNEAVKMLLEAGADVDGCDPDGRTALRAAAWGGHEEVLMTLLEHGAKVDCMDHEGRTPLIAAAYMGHKEAVEIILDAGAEVDLADGDGRTALSVAALCVPSATGGRGHREVVSLLLERSAEP-EHKDKDGMTPLLLASYEGHEEVVELLLEAGAD--VDEGTGAYPSAVTPLLAA-----AAMGHAGTVNRMLFWGAAVDGIDGEGRTALCLAAAKGSVEVVKALLDRGLDENHKDDLGWTPLHAAACDGHKSVCAVLTERGSMARVGELDVEGRTALILAAQEGHCSTVRLLLDRKSPIDHRSYDGHSALSAASLQGHTEVVELLLRRGADTDVRDA 964 HSP 3 Score: 135.576 bits (340), Expect = 1.236e-31 Identity = 102/335 (30.45%), Postives = 158/335 (47.16%), Query Frame = 2 Query: 1736 NGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGS--NINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNA----DIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCID-----------------------------------KSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKP 2617 + T L+ AA G N +L GA ID +G +AL LA G +EVVK LL + +D + + G T L AA G + +L GS + + D EGRT L+ A + V+LLL+ + IDH+ DG SA+ A+L + ++++LLLR + ++ D EG +L + EG + +L+E D R+ L AA+ G+ + + LLL GA + +D K G + LSI+A +G+ +I++ LL +G D H D++G TP+ +A G + + LL GAKP Sbjct: 798 SAVTPLLAAAAMGHAGTVNRMLFWGAAVDGIDGEGRTALCLAAAKGSVEVVKALLDRGLDENHKDDLGWTPLHAAACDGHKSVCAVLTERGSMARVGELDVEGRTALILAAQEGHCSTVRLLLDRKSPIDHRSYDGHSALSAASL-----QGHTEVVELLLRRGADTDVRDAEGRPLLYLLILEGRLDIATLLIEKGGVPLESRDAEGRTALHVAAWQGDLDGIGLLLGHGADPNALDQEGRPPLHSVAWRGLTSAGRLFLRARDINVDQACKKQGATALSIAAQEGHVEIVAMLLEKGADPDHVDHYGRTPVKVAGKRGLFNIIRLLESYGAKP 1127
BLAST of Ankyrin repeat domain 50 vs. Ensembl Cavefish
Match: ank3b (ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2]) HSP 1 Score: 230.72 bits (587), Expect = 5.293e-61 Identity = 164/545 (30.09%), Postives = 267/545 (48.99%), Query Frame = 2 Query: 1706 NGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 +G+DIN N+NG +L +A++ G + L+ GA K G +AL +A G +VVK L++ + + +G T L AA D+V LL +GS+ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +V+LLL GA I K G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL +++ N L ++ G+ K+A+ ++D + N K+ +G T L IA + +E LL GA +G TP+H++ + L+ H + N N+ G TA+H+A+ G E++K L+ GA +D K + +T LH+ + G +I Q L+ G D T + G T L +A++EGH ++ ++L++ GA++ TP VA K I++ NLL + A D Sbjct: 10 SGVDINICNQNGLNALHLASKEGHVEVVTQLIKMGATVDAATKKGNTALHIASLAGQSDVVKELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRYLLDNGSSQSIATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFKARNDITPLHVASKRGNSNMVKLLLERGARIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHEVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKK-ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVTQLMNHGASPNTTNVR-----GETALHMAARAGQTEVVKYLVQNGAYVDAKSKDDQTPLHISSRLGKPEIIQQLLQHGACPDSTTTSGYTPLHLAAREGHKDVASILLDQGASLGITTKKGFTPLHVAAKYGKIEVANLLLQKRAPPD 539 HSP 2 Score: 212.231 bits (539), Expect = 3.500e-55 Identity = 169/669 (25.26%), Postives = 307/669 (45.89%), Query Frame = 2 Query: 1526 INLVNINKLNA-----KKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLID--VWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 IN+ N N LNA K+ T ++ + +T + + N +L + + + +L+ NG ++N ++NG T L +AAQ + LL +G++Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ G+ ++ + TPL A+ + + MVKLLL GA ID + DG + + A L + + +L+ ++LLL + ++ + N+ + L +AA+ G + K++++ A+ + + +PL A +V+ LLL GA+I + +SG + + ++A G+ I+++L+ G + G T LH+A+ GQ E V L+++GA + + PL +S + G +I ++L+ P+S Y T L +A + LL +GA I G TPLH++ + + +LLQ + + G T +H+A+ + ++ L+D GA G T LH+ A + +I L+++G + + QG + L +ASQEG++++ LL+ A + + TP +A + + + + +L HGA VD Sbjct: 14 INICNQNGLNALHLASKEGHVEVVTQLIKMGATVDAATKKGNT---ALHIASLAGQSDVVKELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRYLLDNGSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFKARNDITPLHVASKRGNSNMVKLLLERGARIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHEVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVTQLMNHGASPNTTNVRGETALHMAARAGQTEVVKYLVQNGAYVDAKSKDDQTPLHISSRLGKPEIIQQLLQHGACPDSTTTSGY---TPLHLAAREGHKDVASILLDQGASLGITTKKGFTPLHVAAKYGKIEVANLLLQKRAPPDASG-----KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMEIATTLLEYGADTNAITRQGISPLHLASQEGNVDMVTLLMARDATINLCNKSGLTPLHLAAQEDQVNVAEVLVNHGATVD 671 HSP 3 Score: 201.445 bits (511), Expect = 8.192e-52 Identity = 161/557 (28.90%), Postives = 260/557 (46.68%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 S R NS N + L+ G I+ ++G T L A++G + +LL GA L K+G S L +A ++ V+LLL ++ D ND TAL AA G + +++ +N N + G TPL A K +++LLL +GA I G + I VAA + N I+ L+ + + N + G L +AA G + K L++N A +D D++PL ++ G E+++ LL GA SG++ L ++A +G+ + S LL +G G TPLH+A+ G+ E NLLL+ A P+ G PL ++ YD K+A+L LL +GA NG TPLHI+ ++Q + LL++ + N + G + +H+AS +G+ +++ L+ A I+L + G T LHL A + + ++L++ G +D G T L +A G++++ + L+ A V +T A +G H I NLL +HGA Sbjct: 223 SKRGNS-NMVKLLLERGARIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHEVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHEN-----IVTQLMNHGASPNTTNVRGETALHMAARAGQTEVVKYLVQNGAYVDAKSKDDQTPLHISSRLGKPEIIQQLLQHGACPDSTTTSGYTPLHLAAREGHKDVASILLDQGASLGITTKKGFTPLHVAAKYGKIEVANLLLQKRAPPDASGKSGLTPLHVAAH----------------------YDNQ---KVALL---------LLDQGASPHAAAKNGYTPLHIAAKKNQMEIATTLLEYGA-----DTNAITRQGISPLHLASQEGNVDMVTLLMARDATINLCNKSGLTPLHLAAQEDQVNVAEVLVNHGATVDPETKMGYTPLHVACHYGNVKMVHFLLKNQAKV-----NAKTKVTAAQQG-HTHIINLLLQHGA 728 HSP 4 Score: 159.073 bits (401), Expect = 1.047e-38 Identity = 128/482 (26.56%), Postives = 217/482 (45.02%), Query Frame = 2 Query: 1898 LSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 L +D + +G AL A+ G ++V L+ G+ ++ +G T L A+ +VK L+ NGA ++ Q +G + +++AA +LD+++ LL + ++ +G L +A +G + +LLEN+ + R P L AA + + LLL KSGF+ L I+A GN + + LL RG + TPLH+AS G V LLL+ GA+ ++ K+ DG T L + + VE LL RGA + NG +PLH++ +C Q+LL H + ++ + +D TA+H+A+ G ++ K ++D A + K G T LH+ + ++ +LL+ G +I G T + +A+ GH I L+N GA+ + T +A + ++ L ++GA VD K+ Sbjct: 8 LKSGVDINICNQNGLNALHLASKEGHVEVVTQLIKMGATVDAATKKGNTALHIASLAGQSDVVKELVTNGANVNAQSQNGFTPLYMAA-----QENHLDVVRYLLDNGSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFKARNDITPLHVASKRGNSNMVKLLLERGAR----------------------------------IDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHEVP-----VDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVTQLMNHGASPNTTNVRGETALHMAARAGQTEVVKYLVQNGAYVDAKS 443 HSP 5 Score: 156.377 bits (394), Expect = 5.798e-38 Identity = 129/465 (27.74%), Postives = 215/465 (46.24%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y ++ + N NG T L +A + + LLL GA+ + + G + + +A + G+ +V L++ P+ T G TAL AA G+T++V L+ +G+ ++ + + +TPL ++ +++ LL +GA D G + + +AA + D+ +LL ++ + +G L +AA G + +LL+ A D +S PL AA N +V LLL GA+ H K+G++ L I+A + +I + LL G D G +PLHLAS EG + V LL+ A N + G PL L+ QE + +AE L++ +V+ ++ G T L +A + V FLL A N +T + + Q +LLQH N +N G TA+ IA G ++ +L Sbjct: 309 DVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVTQLMNHGASPNTTNVRGETALHMAARAGQTEVVKYLVQNGAYVDAKSKDDQTPLHISSRLGKPEIIQQLLQHGACPDSTTTSGYTPLHLAA-----REGHKDVASILLDQGASLGITTKKGFTPLHVAAKYGKIEVANLLLQKRAPPDASGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMEIATTLLEYGADTNAITRQGISPLHLASQEGNVDMVTLLMARDATINLCNKSGLTPLHLAAQEDQVNVAEVLVNHG-ATVDPETKMGYTPLHVACHYGNVKMVHFLLKNQAKV-----NAKTKV-TAAQQGHTHIINLLLQHGAAPNELTVN-----GNTALSIARRLGYISVVDTL 756
BLAST of Ankyrin repeat domain 50 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 226.483 bits (576), Expect = 1.278e-59 Identity = 161/544 (29.60%), Postives = 264/544 (48.53%), Query Frame = 2 Query: 1709 GLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 G+DIN N+NG +L +A++ G + LL GA+ K G +AL +A G +VV+ L++ + + +G T L AA ++V LL G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D + R +PL AA GN +V+LLL GA I K G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ ++D + N K+ +G T L IA + +E LL GA +G TP+H++ + + L H + N N+ G TA+H+A+ G ++++ L+ GA++D+K + +T LH+ + G +I QLL+ G + G T L +A +EGH E +LL+ GA++ TP VA K I+ LL + A D Sbjct: 66 GVDINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKK-ANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVR-----GETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPD 594 HSP 2 Score: 202.986 bits (515), Expect = 2.441e-52 Identity = 158/556 (28.42%), Postives = 258/556 (46.40%), Query Frame = 2 Query: 1652 LFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLE 3310 L + ++ + N + L+ G I+ ++G T L A++G + +LL GA L K+G S L +A ++ V+LLL + D ND TAL AA G + +++ +N N + G TPL A K +++LLL +GA + G + I VAA + N I+K L + + N + G L +AA G + + LL+N A +DI D++ L A+ G E+V+LLL GA SG++ L ++ +G+ + S LL G G TPLH+A+ GQ E LLL+ A P+ G PL ++ ++A L+D S + + +G T L IA E LL GA+ G +PLH++ + D +LL T N N +N + +G T +H+A+ + + + L++ GA +D G T LH+ G ++ L++ I+ G T L A+Q+GH I N+L+ A+ + T +A + +I + + L Sbjct: 274 LHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHEN-----IVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHG-ASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLL----TKNAN-VNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLNGNTALSIARRLGYISVVDTLR 818 HSP 3 Score: 202.216 bits (513), Expect = 4.421e-52 Identity = 169/632 (26.74%), Postives = 288/632 (45.57%), Query Frame = 2 Query: 1526 INLVNINKLNA-----KKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKID-------------PDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 IN+ N N LNA K+ +L + ++ + + N +L + + + +L+ NG ++N ++NG T L +AAQ + LL GA+Q + +DG++ L +A+ G+ +VV LLL ++K D D G T L AA G ++ LLL+ G+ ++ TPL A + + MVKLLL+ GA ID + DG + + A S + ++++LL I G++ L +A +G L C ++LL+++ +D V L A AA G+++V ++++ A + +GF+ L I+ + +++ LL G G TP+H+A+ G V L GA PN + G L ++ + G + L+ + V+ K+ D T+L IA E V+ LL +GA A+ +G TPLH++V + + +LL+H + ++ G T +H+A+ G E K L+ A D G T LH+ A ++ LL+D G + G T L IA+++ LEI L+ FGA + +P +A + + + +LL Sbjct: 69 INICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNT---ALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGA-----RSGHEQVVEMLLDRGAPILSKTKNGLSPLHMAT-QGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAK-VDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGAS-----LSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLL 685 HSP 4 Score: 167.933 bits (424), Expect = 1.613e-41 Identity = 134/465 (28.82%), Postives = 215/465 (46.24%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y ++ + N NG T L +A + + LLL GA+ + + G + + +A + G+ +VK L P+ T G TAL AA G+ D+V LL +G+ ++ + + +T L A+ +V+LLL GA+ G + + +A + + LLL + +++ +G L +AA G K+LL+ A D + +PL AA N V LLL GA+ H K+G++ L I+A + +I + LL G + G +PLHLA+ EG + V+LLL A N + +G PL L+ QE + +AE L++ E V+ + G T L +A + V FLL A + +G TPLH + Q +LLQH + N +N G TA+ IA G ++ +L Sbjct: 364 DVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAV-----REGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAE-VDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLN-----GNTALSIARRLGYISVVDTL 817 HSP 5 Score: 142.124 bits (357), Expect = 1.608e-33 Identity = 129/498 (25.90%), Postives = 211/498 (42.37%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 A G +E L +D + +G AL A+ G ++V LL G++++ +G T L A+ +V+ L+ NGA ++ Q +G + +++AA +L++++ LL + + ++ +G L +A +G + +LLEN+ + R P L AA + + LLL KSGF+ L I+A GN + + LL RG +D M R++ TPLH+A+ G V LLL GAK ++ K+ DG T L + + VE LL RGA + NG +PLH++ +C Q+LLQH + +D N+ T LH+ A G Y++ ++++D N + G T L IA ++ +++ LL+ GA++ + TP VA H I L HGA + NV Sbjct: 50 AARAGNLEKALDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAA-----QENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDI--TPLHVAAKRGNGNMVKLLLDRGAK----------------------------------IDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVP--------------------------------------VDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNV 466 HSP 6 Score: 137.887 bits (346), Expect = 3.229e-32 Identity = 104/373 (27.88%), Postives = 175/373 (46.92%), Query Frame = 2 Query: 1589 ILNITSTYSNSIEATNVY-SFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 I+ + + S TNV +L + R + + L+ NG ++ ++ T+L +A++ G I LLL GA G++ L LA+ G+ E LLL G T L AA G+ + LLL + + G TPL A + + + LLL++GA +G + + +AA L+I LL + N + +G++ L +AA EGS L +LL NA++++ ++ +PL AA V +LL GA + K+G++ L ++ GN +++S LL + G TPLH A+ +G +N+LL+ A NE+ +G L ++ + GYI + + L Sbjct: 450 IVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAA-----KKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLNGNTALSIARRLGYISVVDTL 817
BLAST of Ankyrin repeat domain 50 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 219.55 bits (558), Expect = 1.989e-57 Identity = 161/552 (29.17%), Postives = 265/552 (48.01%), Query Frame = 2 Query: 1709 GLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLID--------NEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 G+DIN N+NG +L +A++ G + LL GA+ K G +AL +A G +VV+ L++ + + +G T L AA ++V LL G++ + +G TPL A + +V LLL +ND + + + AL + + LLL+ + N ++ + G L IAA+ G+ + +LL A +D + R +PL AA GN +V+LLL GA I K G + L A G+ Q++ LL RG + + G +PLH+A+ CV LLL+ +++ N L ++ G+ K+A+ ++D + N K+ +G T L IA + +E LL GA +G TP+H++ + + L H + N N+ G TA+H+A+ G ++++ L+ GA++D+K + +T LH+ + G +I QLL+ G + G T L +A +EGH E +LL+ GA++ TP VA K I+ LL + A D Sbjct: 30 GVDINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLL---------ENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKVHTYTHTHSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKK-ANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVR-----GETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPD 566 HSP 2 Score: 202.986 bits (515), Expect = 2.463e-52 Identity = 158/556 (28.42%), Postives = 258/556 (46.40%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 L + ++ + N + L+ G I+ ++G T L A++G + +LL GA L K+G S L +A ++ V+LLL + D ND TAL AA G + +++ +N N + G TPL A K +++LLL +GA + G + I VAA + N I+K L + + N + G L +AA G + + LL+N A +DI D++ L A+ G E+V+LLL GA SG++ L ++ +G+ + S LL G G TPLH+A+ GQ E LLL+ A P+ G PL ++ ++A L+D S + + +G T L IA E LL GA+ G +PLH++ + D +LL T N N +N + +G T +H+A+ + + + L++ GA +D G T LH+ G ++ L++ I+ G T L A+Q+GH I N+L+ A+ + T +A + +I + + L Sbjct: 245 PLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHEN-----IVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHG-ASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLL----TKNAN-VNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLNGNTALSIARRLGYISVVDTL 789 HSP 3 Score: 196.823 bits (499), Expect = 2.025e-50 Identity = 170/640 (26.56%), Postives = 289/640 (45.16%), Query Frame = 2 Query: 1526 INLVNINKLNA-----KKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLL----------------SQKIDPDFTG----ND-----------------GRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 IN+ N N LNA K+ +L + ++ + + N +L + + + +L+ NG ++N ++NG T L +AAQ + LL GA+Q + +DG++ L +A+ G+ +VV LLL ++K D ND G T L AA G ++ LLL+ G+ ++ TPL A + + MVKLLL+ GA ID + DG + + A S + ++++LL I G++ L +A +G L C ++LL+++ +D V L A AA G+++V ++++ A + +GF+ L I+ + +++ LL G G TP+H+A+ G V L GA PN + G L ++ + G + L+ + V+ K+ D T+L IA E V+ LL +GA A+ +G TPLH++V + + +LL+H + ++ G T +H+A+ G E K L+ A D G T LH+ A ++ LL+D G + G T L IA+++ LEI L+ FGA + +P +A + + + +LL Sbjct: 33 INICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNT---ALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKVHTYTHTHSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGA-----RSGHEQVVEMLLDRGAPILSKTKNGLSPLHMAT-QGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAK-VDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGAS-----LSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLL 657 HSP 4 Score: 168.318 bits (425), Expect = 1.586e-41 Identity = 134/465 (28.82%), Postives = 215/465 (46.24%), Query Frame = 2 Query: 1625 EATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 + TN Y +L + Y ++ + N NG T L +A + + LLL GA+ + + G + + +A + G+ +VK L P+ T G TAL AA G+ D+V LL +G+ ++ + + +T L A+ +V+LLL GA+ G + + +A + + LLL + +++ +G L +AA G K+LL+ A D + +PL AA N V LLL GA+ H K+G++ L I+A + +I + LL G + G +PLHLA+ EG + V+LLL A N + +G PL L+ QE + +AE L++ E V+ + G T L +A + V FLL A + +G TPLH + Q +LLQH + N +N G TA+ IA G ++ +L Sbjct: 336 DVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAV-----REGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAE-VDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLN-----GNTALSIARRLGYISVVDTL 789 HSP 5 Score: 138.272 bits (347), Expect = 2.532e-32 Identity = 104/373 (27.88%), Postives = 175/373 (46.92%), Query Frame = 2 Query: 1589 ILNITSTYSNSIEATNVY-SFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 I+ + + S TNV +L + R + + L+ NG ++ ++ T+L +A++ G I LLL GA G++ L LA+ G+ E LLL G T L AA G+ + LLL + + G TPL A + + + LLL++GA +G + + +AA L+I LL + N + +G++ L +AA EGS L +LL NA++++ ++ +PL AA V +LL GA + K+G++ L ++ GN +++S LL + G TPLH A+ +G +N+LL+ A NE+ +G L ++ + GYI + + L Sbjct: 422 IVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAA-----KKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLNGNTALSIARRLGYISVVDTL 789 HSP 6 Score: 135.961 bits (341), Expect = 1.303e-31 Identity = 129/506 (25.49%), Postives = 213/506 (42.09%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP-LMAAAFSGNFEVVRLLLF------WGAAIHCIDK--SGFSVLSISASQGNSQILSELLARG--LDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 A G +E L +D + +G AL A+ G ++V LL G++++ +G T L A+ +V+ L+ NGA ++ Q +G + +++AA +L++++ LL + + ++ +G L +A +G + +LLEN+ + R P L AA + + LLL + +H SGF+ L I+A GN + + LL RG +D M R++ TPLH+A+ G V LLL GAK ++ K+ DG T L + + VE LL RGA + NG +PLH++ +C Q+LLQH + +D N+ T LH+ A G Y++ ++++D N + G T L IA ++ +++ LL+ GA++ + TP VA H I L HGA + NV Sbjct: 14 AARAGNLEKALDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAA-----QENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKV--RLPALHIAARKDDTKSAALLLQNDHNADVESKVHTYTHTHSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDI--TPLHVAAKRGNGNMVKLLLDRGAK----------------------------------IDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVP--------------------------------------VDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNV 438
BLAST of Ankyrin repeat domain 50 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 243.047 bits (619), Expect = 1.822e-67 Identity = 174/561 (31.02%), Postives = 278/561 (49.55%), Query Frame = 2 Query: 1736 NGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVA---------ALCLNSNSKY---------------LDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 + TS + AA+NG L G + +++G +AL LA G+++VV LL ++ + D G TAL AA G+TDIV +L+ G+NIN Q G TPL A + +VK LL+NGA DG + + VA L L S++K + LLL++ N ++ G L IAA+ G+ + +LL A +D R +PL AA GN +V+LLL GA I + G + L +A G+ +++ LL R + + G +PLH+A+ CV LLL A +++ PL ++ G+ ++A+ L+D E N ++ +G T L IA + +E LL GA +G TP+H++ + Q+LLQ+ + N N+ G T +H+AS G E++K+L+ GAR+ +K E +T LH+ + G +I QLL+ G + + + G+T L AS+EGH ++ +LL+ GA++ + TP +A K +++ LL + A D K Sbjct: 10 DAATSFLRAARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEP-NARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVR-----GETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPK 564 HSP 2 Score: 196.052 bits (497), Expect = 6.845e-52 Identity = 166/568 (29.23%), Postives = 269/568 (47.36%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSR--GADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 +L + R++ N + L+ + + + +++G T L +AA G ++ LLL+ GA ++G + L +A G +VKLLL + D DG T L AA G ++ +LL + I + G +PL AT V+LLL A +D D + + VAA C + + KLLL N G L IA + + ++LL++ A I S P+ A+F G+ VV+LLL GA+ + + G + L +++ G +++ LL G + TPLH+AS G+ E V LLL+ G+ PN G PL + +EG+ +A L++ + ++ + G T L IA E LL + AD + NG TPLH++ + YD +V L L + + +G T +HIA+ K E+ K L+++GA ++ +G LHL A +G + LL+ +I G TA+ +A+QE + + +L A+V TP VA +IK+ N L ++ ALV+ K Sbjct: 175 ALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHC-----GHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGAD-ISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVA---THYDHQKVALL--LLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAK 731 HSP 3 Score: 181.415 bits (459), Expect = 3.360e-47 Identity = 156/562 (27.76%), Postives = 252/562 (44.84%), Query Frame = 2 Query: 1652 LFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLK--SGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 L + ++ + N + L+ G I+ +G T L AA++G + +LL A L K+G S L +A ++ V+LLL ++ D D T L AA G + LLL G N + G TPL A K +++LLL +GA I G + I VA+ +L++++LLL+ + N + G L +A+ G + K LL++ A + + D++PL A+ G E+V+LLL G+ + SG + L ++ +G+ + S LL G D G TPLH+AS G+ E LLL+ + A P +G PL ++ YD K+A+L LL +GA NG TPLHI+ ++Q + +VLL+ N L G +H+A+ +G +++ L+ A I L G T +HL A + + ++L +++ T T L +AS G++++ N L+ A V TP A + H + N L +H A Sbjct: 242 LHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFM-----GHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATH----------------------YDHQ---KVALL---------LLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGA-----ETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEA 759 HSP 4 Score: 137.502 bits (345), Expect = 2.958e-33 Identity = 126/453 (27.81%), Postives = 196/453 (43.27%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLEN--NADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 ++N + L+ +G I+ E+G T + VA+ G ++ LLL +GA+ + G + L +A G +EVVK LL + +T L A+ +G+ +IV LLL GS+ N + G TPL A+ + + LLL NGA +I+ + +G L IA+ G + +LLE +AD + + +PL A + +V LLL GA+ H K+G++ L I+A + ++ LL G + G PLHLA+ EG + V LLL A + G + L+ QE + +AE ++ VN + T L +A + V FLL A + NG TPLH + Q LLQH + N L +G TA+ IA G ++ +L Sbjct: 379 KKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGA--------------------------------------DISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAE-ILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEAS-----PNELTANGNTALAIARRLGYISVVDTL 787 HSP 5 Score: 127.102 bits (318), Expect = 6.307e-30 Identity = 104/398 (26.13%), Postives = 184/398 (46.23%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L S ++D++ LL+ I+ G L IAA G + ++L+E A+I+ + +PL AA + E+V+ LL GA + GF+ L+++ QG+ Q++ LL + + LH+A+ + LLL+ + G PL ++ G + +A L+++ +V+F + +G T L +A V+ LL RGA + +G TPLH + ++LL+ I +G + +H+A+ ++ L+ A +D + T LH+ A G Y++ +LL+D G + G T L IA ++ +++ LL+ GA++ TP VA H+ + LL ++GA + NV Sbjct: 47 ALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLL----ESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLG-AAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAP-----ILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNV 434
BLAST of Ankyrin repeat domain 50 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 237.269 bits (604), Expect = 4.124e-65 Identity = 175/569 (30.76%), Postives = 278/569 (48.86%), Query Frame = 2 Query: 1736 NGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVA---------ALCLNSNSKY---------------LDIIKLLLRYNCN--------INLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 + TS + AA+NG L G + +++G +AL LA G+++VV LL ++ + D G TAL AA G+TDIV +L+ G+NIN Q G TPL A + +VK LL+NGA DG + + VA L L S++K + LLL++ N +N G L IAA+ G+ + +LL A +D R +PL AA GN +V+LLL GA I + G + L +A G+ +++ LL R + + G +PLH+A+ CV LLL A +++ PL ++ G+ ++A+ L+D E N ++ +G T L IA + +E LL GA +G TP+H++ + Q+LLQ+ + N N+ G T +H+AS G E++K+L+ GAR+ +K E +T LH+ + G +I QLL+ G + + + G+T L AS+EGH ++ +LL+ GA++ + TP +A K +++ LL + A D K Sbjct: 9 DAATSFLRAARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEP-NARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVR-----GETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPK 571 HSP 2 Score: 197.978 bits (502), Expect = 2.848e-52 Identity = 156/566 (27.56%), Postives = 264/566 (46.64%), Query Frame = 2 Query: 1718 INCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLN-------------SNSKYLD---------------IIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNAD---IDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 +N E+G T L +AA G ++ LLL+ GA ++G + L +A G +VKLLL + D DG T L AA G ++ +LL + I + G +PL AT V+LLL A +D D + + VAA C + N++ L+ +++LLL++ +I+ G+ + +A++ G + ++LL+N A ++ +PL A+ +G EVV+ LL GA + + + L I++ G ++I+ LL RG D G TPL+ AS EG + +LLL++GA + + G PL ++ + G +++A L++ + S + K +G T L +A + LL +GA NG TPLHI+ ++Q + +VLL+ N L G +H+A+ +G +++ L+ A I L G T +HL A + + ++L +++ T T L +AS G++++ N L+ A V TP A + H + N L +H A Sbjct: 205 LNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKY-ASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGA-----ETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEA 764 HSP 3 Score: 193.356 bits (490), Expect = 9.320e-51 Identity = 166/575 (28.87%), Postives = 265/575 (46.09%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMA---ATYKCDYVMVKLLLNNGAYID--------HQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELL---ARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 +L + ++ + +++L+ +I+ + G T+L +AA G T I +L+ GAN ++G++ L +A ++E+VK LL + DG T L A G +V LLL S D++G+ L A A K D LLL + D G + + +AA N N + LLL ++ G+ L +AA G+ + K+LL+ A ID R +PL AA SG+ +V+ +LL A I K+G S L + A+QG +LL +D++ D TPLH+A+ G Y LLL G +PN +G PL ++C++ IK+ E L+ S++ + G T + +A V+ LL GA + + G TPLH++ Q + + LLQ + + +T +HIAS G EI++ L+ G+ + G T L+ + +G + LL++ G +I +G T L IAS+ G LE+ LL+ A+ TP VA +H K+ LL GA Sbjct: 46 ALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLES-------DTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMN-----VATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHM-ATQGEHLACVQLLLGRQAPVDDVTLDYL--TPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLK-HGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGA-----RVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGA 599 HSP 4 Score: 139.043 bits (349), Expect = 1.301e-33 Identity = 129/450 (28.67%), Postives = 196/450 (43.56%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKY--LDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 ++N + L+ +G I+ E+G T + VA+ G ++ LLL +GA+ + G + L +A G +EVVK LL + +T L A+ +G+ +IV LLL GS+ N + G TPL A+ + + LLL NGA I G + + +A SKY L++ LLL + D +G N L +PL A + +V LLL GA+ H K+G++ L I+A + ++ LL G + G PLHLA+ EG + V LLL A + G + L+ QE + +AE ++ VN + T L +A + V FLL A + NG TPLH + Q LLQH + N L +G TA+ IA G ++ +L Sbjct: 386 KKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIA-------SKYGRLEVATLLLEKYAS---ADPKGKNGL---------------------------TPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAE-ILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEAS-----PNELTANGNTALAIARRLGYISVVDTL 792 HSP 5 Score: 124.02 bits (310), Expect = 6.067e-29 Identity = 109/418 (26.08%), Postives = 190/418 (45.45%), Query Frame = 2 Query: 2210 LRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDI---VDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAK-----P--------------------------------NEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 L+ +IN + G+N L +A+ EG + LL+ A+ID V + L AA +G ++VR+L+ +GA I+ ++GF+ L ++A + + +I+ LL G ++ G TPL +A +G + V LLL+S K P N+ G PL ++ G + +A L+++ +V+F + +G T L +A V+ LL RGA + +G TPLH + ++LL+ I +G + +H+A+ ++ L+ A +D + T LH+ A G Y++ +LL+D G + G T L IA ++ +++ LL+ GA++ TP VA H+ + LL ++GA + NV Sbjct: 30 LKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLG-AAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAP-----ILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNV 441 HSP 6 Score: 95.5153 bits (236), Expect = 3.749e-20 Identity = 110/462 (23.81%), Postives = 183/462 (39.61%), Query Frame = 2 Query: 1379 IFKFKGYHFAVWLLY----SDCDIEVKGILP---CEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTY-----ILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESV 2719 + F G+ V LL S V+G P + G L ++VK L +S V + + I S + + S+ T S L+ + R+ + S L+ NG DI+ V + G T L +A++ G + LLL A+ K+G + L +A + +V LLL + P T +G T L AA + ++ +LL G+ N +G PL A + MV LLL GR A +I+L G+ + +AA E + +IL ++ AD++ + +PL A+ GN ++V LL A ++ ++G++ L +A QG++ + VN LL+ A PNE+ +G L ++ + GYI + + L + E V Sbjct: 416 VASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQL------EVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLL------------GRHA--------------------------SISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHV---------------------------------VNALLQHEASPNELTANGNTALAIARRLGYISVVDTLSILTEEPV 800
BLAST of Ankyrin repeat domain 50 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 194.126 bits (492), Expect = 1.989e-50 Identity = 153/534 (28.65%), Postives = 243/534 (45.51%), Query Frame = 2 Query: 1730 NENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 ++G T L AA++G + +LL GA L K+G S L +A ++E V++L+ + D D TAL AA G +LL G+N N + G TPL A K +++LLL GA I+ G + + V+A N L+I+ +LL+ + N + G L +AA G + + LL N A +D R +PL AA G E+V+LLL A+ +G++ L ++A +G+ + + LL G G TPLH+AS G+ E +LLL+ A P+ +G PL ++ YD K+A+L LL +GA NG TPLHI+ + Q + LL++ N + G +H+ + +G ++ L+ A ++ G + LHL A + + ++L+ G +++ T G T L +A G++++ N L+ GA+V TP A + H I NLL K GA Sbjct: 3 RQDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGN-----LNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASH----------------------YDNQ---KVALL---------LLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGA-----ETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGA 492 HSP 2 Score: 180.259 bits (456), Expect = 4.479e-46 Identity = 142/473 (30.02%), Postives = 225/473 (47.57%), Query Frame = 2 Query: 1931 NDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 DG T L AA G +V +LL G+ I + G +PL AT V++L+ A +D D +A+ VAA C + K+LL N N+ G L IA + + ++LL+ A I+ V S P+ +AF GN +V +LL GA+ + + G + L ++A G ++++ LL G + TPLH+A+ G+ E V LLL+ A P+ ++G PL ++ +EG+ + L++ S+ + G T L +A E LL R A NG TPLH++ S YD +V L L + + +G T +HIA+ K EI +L++ GA + +G LHLGA +G + LL+ +++ G + L +A+QE + + +L+ GA+V TP VA +IK+ N L +HGA V+ K Sbjct: 4 QDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHC-----GHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLE-HGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVA---SHYDNQKVALL--LLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKT 465 HSP 3 Score: 177.948 bits (450), Expect = 2.233e-45 Identity = 137/519 (26.40%), Postives = 240/519 (46.24%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLL 3208 + R + L+ G I +NG + L +A Q +L+ A I D +AL +A G+ K+LL + +P+ +G T L A R ++ LLL G++I G TP+ + + + +V +LL GA + + G +A+ +AA + ++++ LLR ++ E L IAA G + ++LL++ A D +PL AA G+ +V +LL GA++ K GF+ L +++ G ++ S LL R G TPLH+AS + LLL GA P+ +G PL ++ ++ ++IA L++ E+ N + G L + + LL+R AD +G +PLH++ + + + ++L++H ++N G T + +A G+ +++ L+ GA ++ K G T LH A QG I LL+ G ++ G TAL+IA + G++ + + L Sbjct: 13 AARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAA-----RAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAET-NAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGA-----HVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTL 520 HSP 4 Score: 157.918 bits (398), Expect = 3.168e-39 Identity = 128/479 (26.72%), Postives = 208/479 (43.42%), Query Frame = 2 Query: 1505 VKILFESINLVNINKLNAKKSFTIF----STYILNITSTYSNSIEATNVYSFS-LFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDN 2833 K+L + N+ LN I ++ + Y SIEA + + S + N + L+ G N N G T+L +AA+ G T + LL +GA ++ + L +A G +E+V+LLL PD ++G T L AA G D+ +LL G+++ +G TPL A+ + LLL A D +G + + VA+ L + + L+I LL Y N I +G+ L + A EG + +LL AD++ +S PL AA V +L+ GA ++ K G++ L ++ GN ++++ LL G D + G TPLH A+ +G VNLLLK GA+PN++ +G L ++ + GYI + + L V E++ + +S ++ V + E +E G D D Sbjct: 88 AKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTLKVVTEETITSTTVSNPSS-RVNVPETMTEVLEVSDDEGEDTMTGDG 565 HSP 5 Score: 58.151 bits (139), Expect = 1.314e-8 Identity = 46/172 (26.74%), Postives = 81/172 (47.09%), Query Frame = 2 Query: 2831 NNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKV-AYKGNHIKICNLLEKHGALVDRKNV 3343 +G TPLH + ++LL+ I +G + +H+A+ E ++ L+ A +D + T LH+ A G Y+ ++L+D G N + G T L IA ++ + + LL+ +GA++ + TP V A+ GN + I +L + GA + NV Sbjct: 4 QDGLTPLHCAARSGHEQVVEILLEQGAP-----ILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGN-LNIVLILLQGGASPNATNV 169
BLAST of Ankyrin repeat domain 50 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008129.1 (pep scaffold:Pmarinus_7.0:GL476358:593185:649018:1 gene:ENSPMAG00000007339.1 transcript:ENSPMAT00000008129.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 178.333 bits (451), Expect = 1.610e-45 Identity = 212/840 (25.24%), Postives = 345/840 (41.07%), Query Frame = 2 Query: 248 KLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKY---FGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPP----PNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLN-KSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIK--------SNGYIIYLEIVLDGILDGYLSIQV--IKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYY--LKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLL--DVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATN------VYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDG---------RTALRTAAWIGRTDIVLLLLSSGSNINKQDSE-----------GRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAK 2614 +L + +++ H+C A + + + +F+ L +S + E+ R ++ + +L ++ P AF+ GIL PL + P EN ILID + N+ FHK G I+ L+ FP WL LV T R + + IV F F LD + + D+Q Y+ +R+ ++Q ++ T L + + S G +YL + LD I G+L ++ K +P L LYL F F V + N+ L+SL L+D++ + A+ + L + + + + FLV+ D F H S EWL + + K+ C GH LA + SKL Q H++ A I+K V S ++ + +S D + L +L N+ N K S ++ + ++ EA VYS+ ++ + S L+ G D N +E+G ++L AA +G I +L GA +D+ G AL A G+++++ LL + + TG + AL A G ++V LL + + +D G T L AA + + +LLL GA G +F A + +++LLL + ++N+ D +G L++++ EG L A + VDR L A A G VVR LL GAAI DKSG + L ++A G+ ++ L+ G H DN G +PL A V LL+ GA+ Sbjct: 332 RLAARVVSYHYCQADNAYTCLVPEFVHSTAALLCRSPQLPAYRELLMREPHALPVLSL---RSCVQDPAAAFRRGILEPLSTLRRERRIPEENFIILIDGL-----------------NEAEFHKPDYG-DTITSFLAKMLPRFPVWLKLVVTVRSKLQAIVEAFP-FHTVSLDGFGEREEISADLQAYVSSRVQSSCEIQQNVSLGTGRLDTIALGRLGGHLCSLSRGSFLYLRLTLDLIEWGHLVLKSSSYKVVPVSLAELYLLQCNMRFPTTSAFERVLPLLNVALASLHPLTDEQAFRAVAAGWMAPPLSWEDFQARMEMLSAFLVRRRDGTRMFCHPSFREWLTWRTGEGQSTKFLCDPRSGHALLAFLFSRQDSKLNRQQTIELGHHIL-KARIYKGLSKRLGV----SSSVLQALWVA----------FSTDGLSTAL---ASLRNLYTPNVK-----VSRLLIQAGADVNHRTEALGNAPILCVYSYLGYQDME-------SVLLEMGADPNLASESGMSALCYAASSGHLGIVRMLTRKGAKVDHVDRAGQCALVHAGLRGHLDIMIHLL--QAEWTLTGRQPGPVQRYQAVQQALTATASSGHVEVVSYLLDMLPDWDVEDLGRPHIDSFDTLWGETALTAAATQGRLEICRLLLEWGANASQASRQGVVPVFGAV-----RKGHWQVVELLLSHGVDVNVTDRQGRTPLMVSSSEGHLQTAAFLHSQGASVAAVDREGLSALSWACLKGRLPVVRFLLENGAAIEHADKSGRTPLDLAAFYGDENVIDCLIEHGASIDHTDNSGMSPLDRAIGCRNSSVVVALLRKGAR 1112 HSP 2 Score: 108.612 bits (270), Expect = 4.745e-24 Identity = 99/356 (27.81%), Postives = 165/356 (46.35%), Query Frame = 2 Query: 2063 YKCDYVMVKLLLNNGAYIDHQDND-GRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLF--W---GAAIHCIDK--SGFSVLSISASQGNSQILSELL-------ARGLDEMHRDNF----GCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGL 3064 Y + + +LL+ GA ++H+ G + I LC+ S Y D+ +LL + NL GM+ L AA G + ++L A +D VDR+ L+ A G+ +++ LL W G + + + L+ +AS G+ +++S LL L H D+F G T L A+ +G+ E LLL+ GA ++ G +P+ + ++G+ ++ E L+ + VN G T L ++ + FL S+GA D G + L + L+ + + LL+ N I D GRT + +A++ GD +I LI+ GA ID DN G + L Sbjct: 746 YTPNVKVSRLLIQAGADVNHRTEALGNAPI----LCVYSYLGYQDMESVLLEMGADPNLASESGMSALCYAASSGHLGIVRMLTRKGAKVDHVDRAGQCALVHAGLRGHLDIMIHLLQAEWTLTGRQPGPVQRYQAVQQALTATASSGHVEVVSYLLDMLPDWDVEDLGRPHIDSFDTLWGETALTAAATQGRLEICRLLLEWGANASQASRQGVVPVFGAVRKGHWQVVELLLSHGVD-VNVTDRQGRTPLMVSSSEGHLQTAAFLHSQGASVAAVDREGLSALSWACLKGRLPVVRFLLE-----NGAAIEHADKSGRTPLDLAAFYGDENVIDCLIEHGASIDHTDNSGMSPL 1091 HSP 3 Score: 95.1301 bits (235), Expect = 6.984e-20 Identity = 95/378 (25.13%), Postives = 153/378 (40.48%), Query Frame = 2 Query: 1961 AWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNIN------LIDNEGMNMLLIA-AYEGSKLLCKILLENNADIDIVD--------------RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARI 3031 +++G D+ +LL G++ N G + L A +V++L GA +DH D G+ A+ A L +LDI+ LL+ + + + + L A A G + LL+ D D+ D + L AAA G E+ RLLL WGA + G + + +G+ Q++ LL+ G+D D G TPL ++S EG + L GA +D G L +C +G RLP V FLL GA D +GRTPL ++ + L++H + I+ D+ G + + A + ++ +L+ GAR+ Sbjct: 780 SYLGYQDMESVLLEMGADPNLASESGMSALCYAASSGHLGIVRMLTRKGAKVDHVDRAGQCALVHAGL-----RGHLDIMIHLLQAEWTLTGRQPGPVQRYQAVQQALTATASSGHVEVVSYLLDMLPDWDVEDLGRPHIDSFDTLWGETALTAAATQGRLEICRLLLEWGANASQASRQGVVPVFGAVRKGHWQVVELLLSHGVDVNVTDRQGRTPLMVSSSEGHLQTAAFLHSQGASVAAVDREGLSALSWACLKG---------------------------------RLP-VVRFLLENGAAIEHADKSGRTPLDLAAFYGDENVIDCLIEHGAS-----IDHTDNSGMSPLDRAIGCRNSSVVVALLRKGARL 1113 HSP 4 Score: 83.1889 bits (204), Expect = 3.072e-16 Identity = 83/368 (22.55%), Postives = 154/368 (41.85%), Query Frame = 2 Query: 2294 LCKILLENNADI----DIVDRSPLMAA-AFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLK-----SGAKPNEIDNHGRI--PLMLSCQEGYIKIAEKLIDVWPE-------SVNFKSYD---GSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 + ++L++ AD+ + + +P++ ++ G ++ +LL GA + +SG S L +AS G+ I+ L +G H D G L A + G + + LL+ +G +P + + + L + G++++ L+D+ P+ + S+D G T+L A E LL GA+A+ G P+ +V KG ++++ L+ G +++ D +GRT L + + +G Q L G ++ +G +ALS A +G L + L+ GA + H D RTP +A + + L +HGA +D Sbjct: 752 VSRLLIQAGADVNHRTEALGNAPILCVYSYLGYQDMESVLLEMGADPNLASESGMSALCYAASSGHLGIVRMLTRKGAKVDHVDRAGQCALVHAGLRGHLDIMIHLLQAEWTLTGRQPGPVQRYQAVQQALTATASSGHVEVVSYLLDMLPDWDVEDLGRPHIDSFDTLWGETALTAAATQGRLEICRLLLEWGANASQASRQGVVPVFGAVR--------------------------------------KGHWQVVELLLSHGVDVNVTDRQGRTPLMVSSSEGHLQTAAFLHSQGASVAAVDREGLSALSWACLKGRLPVVRFLLENGAAIEHADKSGRTPLDLAAFYGDENVIDCLIEHGASID 1081
BLAST of Ankyrin repeat domain 50 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003991.1 (pep scaffold:Pmarinus_7.0:GL484476:255315:281660:1 gene:ENSPMAG00000003623.1 transcript:ENSPMAT00000003991.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 172.555 bits (436), Expect = 7.019e-44 Identity = 164/607 (27.02%), Postives = 273/607 (44.98%), Query Frame = 2 Query: 1634 NVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAK-------PNE-----------IDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISV------------------LQSQYDCF------QVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLID-VGA-RIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSC-MRTPYKVAYKGNHIKICNLL 3307 N + L + S + L+ + D+N ++N T L VAA N ++ ++ + D+ G +AL A +NG+ E+V L+++ + + R A+ AA++G T++V +L++ G+++ +D +G +PL AA+ +VKLLL+ G ID ++ G +A+ VA C N ++ L+ N+N + G L AA LC ++L+ N AD+++ +SPL A G F + L+ G I C D+ G + L I+A G+ +++ L+ G D R G PLHLA++ G +C LL +G K NE D GR L + G ++ L+ + +N K T+L A N + V L++ GA QD TPLH + +QS D Q+ L+H L + + D G T +H A+ G ++ L++ GA + D K + LHL A+ G + ++LI +++D G T L +A+ GH + +LI GA+V + RT A H++ LL Sbjct: 70 NKWLTPLHRACASRSEAAVQTLLKHSADVNARDKNWQTPLHVAAANRAVKCAEAIIPMLSSSNVSDRAGRTALHHAAFNGHSEMVNFLVAKGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGADVRCKDKKGYSPLHAASSSGQIGVVKLLLDLGVDIDDPNSFGNTALHVA--CYNGQDV---VVNELIDCGANVNQANERGFTPLHFAAASTHGALCLELLVNNGADVNVQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCEDRDGNTPLHIAARYGHELLINTLITNGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSAGQKYSIVSSFSNEHVLSAGFEIDTPDEFGRTCLHAAASGGNVECLNLLLSTGAD-MNKKDRFERTALHYAAANCNVQCVVTLVASGARLNEQDERRCTPLHYAAAADGDGSTVSFSVYNTISVQSYIDVHSTCSEAQICLEHLLRKDADP-GIQDKQGYTPVHYAAAYGHRVCLELLLEQPGAFQSDGKSGHPISPLHLAAYHGHHGALEVLIRSLVDLDVREGNGYTPLGLAALRGHTDCVRVLIQHGASVLLKEGPDRRTALHSAATNGHVECLRLL 669 HSP 2 Score: 162.54 bits (410), Expect = 9.233e-41 Identity = 140/498 (28.11%), Postives = 236/498 (47.39%), Query Frame = 2 Query: 1859 AIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGAR------------------IDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTP--YKVAYKGN 3283 AI+NG + V+ L+ +K + + ++ RT L AA++G +I+ LL+ SG+ +N +D++ TPL A V+ LL + A ++ +D + ++ + VAA N K + I +L + N+ D G L AA+ G + L+ A+I D DR + AA+ G+ EVV++L+ GA + C DK G+S L ++S G ++ LL G+D ++FG T LH+A GQ VN L+ GA N+ + G PL + + + +L+ VN +S DG + L + ++ + L+ G + +D +G TPLHI+ ++Y LL ++L N + G +H+A+ G + + L+ G + ID D GRT LH A G + LL+ G ++++ TAL A+ +++ L+ GA + D TP Y A G+ Sbjct: 13 AIFNGDPDEVRSLIYKKEEVNAVDDEKRTPLHAAAYLGEAEIIELLVLSGARVNSKDNKWLTPLHRACASRSEAAVQTLLKHSADVNARDKNWQTPLHVAAA--NRAVKCAEAIIPMLSSS---NVSDRAGRTALHHAAFNGHSEMVNFLVAKGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGADVRCKDKKGYSPLHAASSSGQIGVVKLLLDLGVDIDDPNSFGNTALHVACYNGQDVVVNELIDCGANVNQANERGFTPLHFAAASTHGALCLELLVNNGADVNVQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCEDRDGNTPLHIA---ARYG--HELLINTLITNGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSAGQKYSIVSSFSNEHVLSAGFEIDTPDEFGRTCLHAAASGGNVECLNLLLSTGADMNKKDRFERTALHYAAANCNVQCVVTLVASGARLNEQDERRCTPLHYAAAADGD 500 HSP 3 Score: 152.525 bits (384), Expect = 1.208e-37 Identity = 163/588 (27.72%), Postives = 266/588 (45.24%), Query Frame = 2 Query: 1685 TISQ-LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLS--QK----------------IDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSG--FSVLSISASQGNSQILSELLARGLDEMH-RDNFGCTPLHLASVEGQYECVNLLLKSGAK------PNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWP--ESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDV----GARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLIN-FGANVCHI-DSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 T SQ LI NG +I+C + +G T L +AA+ G + N L+++GA+ G L LA +G+ + + LLS QK + D GRT L AA G + + LLLS+G+++NK+D RT L A C+ V L+ +GA ++ QD + + AA S + + I++ + +++ + LL +AD I D+ +P+ AA G+ + LLL A KSG S L ++A G+ L E+L R L ++ R+ G TPL LA++ G +CV +L++ GA P+ R L + G+++ L++ E+V+ + T + +AV N + LLS+GA +DN G T LH +C +LLQ S+ +++ + GR +H+A+ G I+ +L+ GA I L D G T LH + G +LL++ + + + L A + +LI+ FGA + + D+ R P A +H++ LL H ALV+ Sbjct: 318 TRSQTLIQNGGEIDCEDRDGNTPLHIAARYGHELLINTLITNGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSAGQKYSIVSSFSNEHVLSAGFEIDTPDEFGRTCLHAAASGGNVECLNLLLSTGADMNKKDRFERTALHYAAANCNVQCVVTLVASGARLNEQDERRCTPLHYAAAADGDGSTVSFSVYNTISVQSYIDVH----------STCSEAQICLEHLLRKDADPGIQDKQGYTPVHYAAAYGHRVCLELLLEQPGAFQSDGKSGHPISPLHLAAYHGHHGAL-EVLIRSLVDLDVREGNGYTPLGLAALRGHTDCVRVLIQHGASVLLKEGPDR-----RTALHSAATNGHVECLRLLVENADSNEAVDASDANEQTPVMLAVGNGHTDCASLLLSKGASINAKDNKGCTALHRGAATGHEECVDLLLQRSV-----DVSLRERRGRAPLHMAAACGHMGILSALVQAAMASGAPIPLTDRNGYTPLHWACYNGHDGCVELLLELDV-FQKQEGNAFSPLHCAVLNDNESCAEMLIDTFGAKIINCPDAKGRMPLHAAAFTDHVECLQLLLSHNALVN 883 HSP 4 Score: 132.88 bits (333), Expect = 1.441e-31 Identity = 147/593 (24.79%), Postives = 254/593 (42.83%), Query Frame = 2 Query: 1709 GLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLS----------QKIDP----DFTGNDGRT-------ALRTAAWI------GRTDIVL-LLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNN-GAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD----RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGF---SVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPES---VNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLI----------DFGINI---------DETCSQGA------------------TALSIASQEGHLEICNLLINFGANVCHIDSCMRTP 3259 G +I+ +E G T L AA G NLLLS+GA+ D+ +AL A N ++ V L++ ++ P DG T + ++I I L LL ++ QD +G TP+ A V ++LLL GA+ +DG+S ++ L L + + +++L+R ++++ + G L +AA G ++L+++ A + + + R+ L +AA +G+ E +RLL+ + +D S + + ++ G++ S LL++G +DN GCT LH + G ECV+LLL+ + + GR PL ++ G++ I L+ S + +G T L A N VE LL Q+ N +PLH +VL C ++L+ T INC D GR +H A++ E ++ L+ A +++ D G++ L + G ++L+ D N ETC+ T L +A++ G + +L+N GA++ +D TP Sbjct: 411 GFEIDTPDEFGRTCLHAAASGGNVECLNLLLSTGADMNKKDRFERTALHYAAANCNVQCVVTLVASGARLNEQDERRCTPLHYAAAADGDGSTVSFSVYNTISVQSYIDVHSTCSEAQICLEHLLRKDADPGIQDKQGYTPVHYAAAYGHRVCLELLLEQPGAF----QSDGKSGHPISPLHLAAYHGHHGALEVLIRSLVDLDVREGNGYTPLGLAALRGHTDCVRVLIQHGASVLLKEGPDRRTALHSAATNGHVECLRLLVENADSNEAVDASDANEQTPVMLAVGNGHTDCASLLLSKGASINAKDNKGCTALHRGAATGHEECVDLLLQRSVDVSLRERRGRAPLHMAAACGHMGILSALVQAAMASGAPIPLTDRNGYTPLHWACYNGHDGCVELLLELDV-FQKQEGNAFSPLHCAVLNDNESCAEMLID---TFGAKIINCPDAKGRMPLHAAAFTDHVECLQLLLSHNALVNVTDMAGKSPLMMACENGQATAVEVLVNSTKTDLKLQDANRNTALHLACSRSHETCALLILDKLDDLNLINATNAALQTPLHLAARSGMATVVQVLLNKGASILAVDHNGYTP 995 HSP 5 Score: 131.339 bits (329), Expect = 3.787e-31 Identity = 89/300 (29.67%), Postives = 146/300 (48.67%), Query Frame = 2 Query: 2333 IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEIC-NLLINFGANV 3229 + ++PL+ A F+G+ + VR L++ ++ +D + L +A G ++I+ L+ G +DN TPLH A V LLK A N D + + PL ++ +K AE +I + S N G T+L A N E V FL+++GA+ D R +H + + +VL+ H ++ C D G + +H AS G ++K L+D+G ID ++ G T LH+ + G + LID G N+++ +G T L A+ H +C LL+N GA+V Sbjct: 4 LCSQAPLIQAIFNGDPDEVRSLIYKKEEVNAVDDEKRTPLHAAAYLGEAEIIELLVLSGARVNSKDNKWLTPLHRACASRSEAAVQTLLKHSADVNARDKNWQTPLHVAAANRAVKCAEAIIPMLSSS-NVSDRAGRTALHHAAFNGHSEMVNFLVAKGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGA-----DVRCKDKKGYSPLHAASSSGQIGVVKLLLDLGVDIDDPNSFGNTALHVACYNGQDVVVNELIDCGANVNQANERGFTPLHFAAASTHGALCLELLVNNGADV 297 HSP 6 Score: 105.531 bits (262), Expect = 3.311e-23 Identity = 123/514 (23.93%), Postives = 206/514 (40.08%), Query Frame = 2 Query: 1643 SFSLFESIRQNSY----NTISQ-------LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGW--SALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNIN-KQDSEGRTPLMAATYKCDYVMVKLLLNNG---AYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEV----VRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLA-----------------------RGLDEMHRDNFGCT-----------PLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIA------------------------------------VLNRLPEFVEFLLSRGADATIQDNNGRTP-LHISVLQSQYDCFQVLL 2899 SFS++ +I SY +T S+ L+ D ++ G T + AA G LLL K G S L LA ++G+ +++L+ +D D +G T L AA G TD V +L+ G+++ K+ + RT L +A ++LL+ N +D D + ++ + +A + + D LLL +IN DN+G L A G + +LL+ + D+ + +R +PL AA G+ + V+ + GA I D++G++ L + G+ + LL EM D FG PLH A+ EC+ LLL A N D G+ PLM++C+ G E L++ + + + +T+L +A + + V+ LL++GA D+NG TP L + +S +C ++L Sbjct: 505 SFSVYNTISVQSYIDVHSTCSEAQICLEHLLRKDADPGIQDKQGYTPVHYAAAYGHRVCLELLLEQPGAFQSDGKSGHPISPLHLAAYHGHHGALEVLIRSLVDLDVREGNGYTPLGLAALRGHTDCVRVLIQHGASVLLKEGPDRRTALHSAATNGHVECLRLLVENADSNEAVDASDANEQTPVMLAV-----GNGHTDCASLLLSKGASINAKDNKGCTALHRGAATGHEECVDLLLQRSVDVSLRERRGRAPLHMAAACGHMGILSALVQAAMASGAPIPLTDRNGYTPLHWACYNGHDGCVELLLELDVFQKQEGNAFSPLHCAVLNDNESCAEMLIDTFGAKIINCPDAKGRMPLHAAAFTDHVECLQLLLSHNALVNVTDMAGKSPLMMACENGQATAVEVLVNSTKTDLKLQDANRNTALHLACSRSHETCALLILDKLDDLNLINATNAALQTPLHLAARSGMATVVQVLLNKGASILAVDHNGYTPALSCAPNKSVAECLSLIL 1013
BLAST of Ankyrin repeat domain 50 vs. Ensembl Yeast
Match: AKR1 (Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats; AKR1 has a paralog, AKR2, that arose from the whole genome duplication; any of several human homologs encoding DHHC-type zinc fingers (ZDHHC) can complement temperature sensitivity of yeast akr1 null mutant [Source:SGD;Acc:S000002672]) HSP 1 Score: 79.7221 bits (195), Expect = 1.448e-15 Identity = 63/241 (26.14%), Postives = 103/241 (42.74%), Query Frame = 2 Query: 2468 QGNSQILSELLARGLDEMHRDNFGC---TPLHLASVEGQYECVNLLLKSGAKPN-EIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQ 3178 +G+ + E++ L E++ D T LH AS+ + V+ L+ GA N PL + + GY+ I V+FLL GAD T+ D+ G LH+SV S +L + ++ + +I+C D GRT++ A+++GD + L+ GA I + D EG T LH G +G + + LI G + + G +IA + Sbjct: 83 RGDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYI----------------------------------VDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQE 289 HSP 2 Score: 65.4698 bits (158), Expect = 3.510e-11 Identity = 51/168 (30.36%), Postives = 81/168 (48.21%), Query Frame = 2 Query: 1673 NSYNTISQLIINGLDINC-VNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKI-----DPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVA 2158 N + + L+ G D+N T L AA+ G+ I + LL GA+ M D G++ L L++ + I +V +L + D D GRT+L AA+ G + V LL G++I D+EG TPL T K ++K L+ +GA + + G+ +A Sbjct: 120 NRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIA 287 HSP 3 Score: 55.8398 bits (133), Expect = 3.537e-8 Identity = 59/217 (27.19%), Postives = 93/217 (42.86%), Query Frame = 2 Query: 2000 SSGSNINKQDSEGRTPLMA----ATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNE-GMNMLLIAAYEGSKLLCKILLENNADIDIVDRSP---LMAAAFSGNFEVVRLLLFWGAA-----IHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGA 2611 S +N D PL+ A + D VK +++ G ++ +NDG S + L S + L ++ L+ ++N L AA G + LL++ AD + D L + S N +V +LF + I C D G + L +A QG+S ++ELL G D G TPLH +V+GQ + L++ GA Sbjct: 57 SGNEQVNHNDEAEEDPLLTRYHTACQRGDLATVKEMIH-GKLLE-VNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGA 271 HSP 4 Score: 53.9138 bits (128), Expect = 1.416e-7 Identity = 56/223 (25.11%), Postives = 93/223 (41.70%), Query Frame = 2 Query: 2657 SCQEGYIKIAEKLIDVWPESVN--FKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNN-GRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEII---------KSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHI 3289 +CQ G + +++I VN S + T L A +N V+FL+S+GAD + TPLH + LL+H + DD G +H++ + ++ K L+D ID +D +GRT L A+QG L+ FG +I ++G T L + +G + LI GA+ + + +A + N + Sbjct: 80 ACQRGDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMT-----DDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLD----IDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIAQEMNTV 293
BLAST of Ankyrin repeat domain 50 vs. Ensembl Yeast
Match: NAS6 (Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464]) HSP 1 Score: 67.781 bits (164), Expect = 7.235e-13 Identity = 58/205 (28.29%), Postives = 95/205 (46.34%), Query Frame = 2 Query: 2645 PLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQD---NNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGIN-IDETCSQGATALSIASQEGHLEICNLLI-NFGANVCHIDS 3244 PL +C E ++L+ P + K DG L +V + E FLLS+ + + D ++G TP HI+ + + L L ++N I + G T +H+A K E+ + LI+ GA + +KD + LH A G ++ +LL G + ++ QG T L A EGH + LL+ +GA +D+ Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKIT---NQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDN 206 HSP 2 Score: 51.9878 bits (123), Expect = 1.174e-7 Identity = 51/223 (22.87%), Postives = 99/223 (44.39%), Query Frame = 2 Query: 1643 SFSLFESIRQNSYNTISQLIINGLDINCV-NENGTTSLMVAAQNGFTSICNLLLSSGANQLM---IDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTG--NDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNG-AYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSK 2290 ++ L ++ +N + + +L+ + + +++G L + I + LLS N + D GW+ +A G +EVVK L + + PD N G T L A ++ L+ +G+++ +D + PL A +++LL G + ++ QD G + +F A + ++ L L+ +Y +L+DN+G +A E K Sbjct: 3 NYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVL----LVEKYGAEYDLVDNKGAKAEDVALNEQVK 221 HSP 3 Score: 50.447 bits (119), Expect = 4.431e-7 Identity = 42/140 (30.00%), Postives = 67/140 (47.86%), Query Frame = 2 Query: 2429 DKSGFSVLSISASQGNSQILSELLARGL--DEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSR-GADATIQDNNG 2839 D SG++ I+ S GN +++ L R L D N G T LHLA + +E L+++GA D +IPL + G +K+ E L + +VN++ G T L A+ + L+ + GA+ + DN G Sbjct: 69 DDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKG 208 HSP 4 Score: 46.9802 bits (110), Expect = 6.064e-6 Identity = 47/177 (26.55%), Postives = 90/177 (50.85%), Query Frame = 2 Query: 1991 LLLSSGSNINKQDSEGRTPL-MAATYKCDYVMVKLL--LNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLL--RYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWG-AAIHCIDKSGFSVL--SISASQGNSQIL 2488 LL S S + ++D +GR PL + +++ + LL + N D+ D+ G + +A N L+++K L ++N I N+G+ L +A + + + L+EN A + I D+ PL AA G+ +++ LL G +A++ DK G++ L +++ G++ +L Sbjct: 21 LLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGN-----LEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVL 192
BLAST of Ankyrin repeat domain 50 vs. Ensembl Yeast
Match: AKR2 (Ankyrin repeat-containing protein; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly involved in constitutive endocytosis of Ste3p; AKR2 has a paralog, AKR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005560]) HSP 1 Score: 62.3882 bits (150), Expect = 3.588e-10 Identity = 58/204 (28.43%), Postives = 102/204 (50.00%), Query Frame = 2 Query: 1958 AAWIGRTDIVLLLLSSGS-NINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKY--LDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILL------ENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDN 2533 AA G +V ++ SG+ +IN + + L A + + K LL GA N ++A A L+ ++Y + I+ LLL++ + L D +G+N++ + Y + LL +L +N DID D R+PL+ AA+ G+F V LLL +G+ + D GF+ L + G+ +++ +L+ G + R+N Sbjct: 57 AAKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGA------NPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLILSGANFYERNN 254 HSP 2 Score: 60.8474 bits (146), Expect = 1.086e-9 Identity = 58/245 (23.67%), Postives = 101/245 (41.22%), Query Frame = 2 Query: 2459 SASQGNSQILSELLARGLDEMHRDNFG-CTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNIN-NINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQ-ICQLLIDFGINIDETCSQGATALSIASQEG 3184 +A G+ +++ +++ G +++ D + LH A + ++ LL GA PN+ G G+T+L A V+ LL GAD T++D G +H SV S +L + +N N +I+ D++ RT + A+++GD ++ L+ G+ + DN G LH G + IC L++ G N E +Q +A G Sbjct: 57 AAKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGANPNQAAGPG---------------------------------GATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLILS-GANFYERNNQKQDCFDLAEGMG 267 HSP 3 Score: 58.5362 bits (140), Expect = 5.575e-9 Identity = 57/193 (29.53%), Postives = 93/193 (48.19%), Query Frame = 2 Query: 1760 AAQNGFTSICNLLLSSGANQLMIDK-DGWSALRLAIWNGYIEVVKLLLSQKIDPD-FTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLL------NNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEG-SKLLCKILL 2311 AA++G + ++ SGA + D+ D S L A N V K LL + +P+ G G TAL AA G IV LLL G++ +D +G + + Y + ++V +L N+ ID +DN+ R+ + AA +L ++LLL++ + DN G N L A G +++C ++L Sbjct: 57 AAKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGANPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAY----QGDFL-TVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLIL 244
BLAST of Ankyrin repeat domain 50 vs. Ensembl Yeast
Match: HOS4 (Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate [Source:SGD;Acc:S000001374]) HSP 1 Score: 62.3882 bits (150), Expect = 4.185e-10 Identity = 39/100 (39.00%), Postives = 55/100 (55.00%), Query Frame = 2 Query: 2942 DDDGRTAIHIASWKGDGEIIKSLIDVGA-RIDLKDNEGRTGLHLGAWQGCYQICQLLIDFG--INIDETCSQGATALSIASQEGHLEICNLLINFGANVC 3232 D GRT + IA KG +++K +I+ G I+ +DN G T LH A QG +I +LLI+ G +NI G T L AS GHL++ L+ GA+ Sbjct: 327 DSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPT 426 HSP 2 Score: 53.1434 bits (126), Expect = 2.949e-7 Identity = 34/98 (34.69%), Postives = 54/98 (55.10%), Query Frame = 2 Query: 3038 KDNEGRTGLHLGAWQGCYQICQLLIDFG-INIDETCSQGATALSIASQEGHLEICNLLINFGA--NVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 +D+ GRT L + +G Y + + +I+ G +I++ + G TAL A+ +GH+EI LLI GA N+ I+ TP A H+ + L K+GA Sbjct: 326 RDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGA 423 HSP 3 Score: 51.2174 bits (121), Expect = 9.329e-7 Identity = 40/112 (35.71%), Postives = 63/112 (56.25%), Query Frame = 2 Query: 2519 MHRDNFGCTPLHLASVEGQYECVNLLLKSGAKP-NEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYD--GSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRT 2845 ++RD+ G T L +A +G+Y+ V +++ G N+ DN G L + +G+I+I E LI+ + VN KS + G T L A N + V++LL GAD TI++ G T Sbjct: 324 IYRDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGAD-VNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLT 434
BLAST of Ankyrin repeat domain 50 vs. Ensembl Yeast
Match: AVO2 (Component of a complex containing the Tor2p kinase and other proteins; complex may have a role in regulation of cell growth [Source:SGD;Acc:S000004672]) HSP 1 Score: 54.299 bits (129), Expect = 7.025e-8 Identity = 42/149 (28.19%), Postives = 72/149 (48.32%), Query Frame = 2 Query: 2468 QGNSQILSELLARGLD---EMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDN--HGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLL 2899 +GN I+ LL R D + +N G + LH AS G+Y L++ G +E+ G + L+ +G+ + L+ +P +N + +G + IA +N + + L+ GAD + D NG TPLH+ + C ++LL Sbjct: 15 EGNLLIVKRLLRRNPDLLTNIDSEN-GWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLL 162
BLAST of Ankyrin repeat domain 50 vs. Ensembl Nematostella
Match: EDO42780 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0Q6]) HSP 1 Score: 98.2117 bits (243), Expect = 3.156e-23 Identity = 67/180 (37.22%), Postives = 85/180 (47.22%), Query Frame = 2 Query: 2537 GCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGA 3076 G TPL +A G ECV L SGA N DN GR PL L+ +G+ DG V +LL+ GAD+TI DN GR PLH + S +LLQH + +IN D +G TA+H A++ G E +K LID A I +D EG+T LH A Sbjct: 48 GMTPLFVAVSTGNLECVQFLATSGASLNTRDNLGRTPLALAAYQGW-------------------NDG---------------VYYLLAVGADSTIVDNCGRLPLHAATYYSSGRTVGLLLQHLPSDHINK---QDGEGMTALHWAAYHGRAEHVKLLIDHDAEIVARDTEGKTALHWAA 190 HSP 2 Score: 70.4774 bits (171), Expect = 1.312e-13 Identity = 51/153 (33.33%), Postives = 73/153 (47.71%), Query Frame = 2 Query: 2735 DGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLID--VGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGH 3187 +G T L +AV E V+FL + GA +DN GRTPL ++ Q D LL I +D+ GR +H A++ G + L+ I+ +D EG T LH A+ G + +LLID I ++G TAL A+Q H Sbjct: 47 EGMTPLFVAVSTGNLECVQFLATSGASLNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTI-----VDNCGRLPLHAATYYSSGRTVGLLLQHLPSDHINKQDGEGMTALHWAAYHGRAEHVKLLIDHDAEIVARDTEGKTALHWAAQVSH 194 HSP 3 Score: 68.5514 bits (166), Expect = 6.009e-13 Identity = 45/147 (30.61%), Postives = 71/147 (48.30%), Query Frame = 2 Query: 2417 IHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWP-ESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLH 2854 I ++ G + L ++ S GN + + L G RDN G TPL LA+ +G + V LL GA +DN GR+PL + + L+ P + +N + +G T+L A + E V+ L+ A+ +D G+T LH Sbjct: 41 IEALNSEGMTPLFVAVSTGNLECVQFLATSGASLNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTIVDNCGRLPLHAATYYSSGRTVGLLLQHLPSDHINKQDGEGMTALHWAAYHGRAEHVKLLIDHDAEIVARDTEGKTALH 187 HSP 4 Score: 64.3142 bits (155), Expect = 1.732e-11 Identity = 53/162 (32.72%), Postives = 84/162 (51.85%), Query Frame = 2 Query: 1826 IDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNN--GAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAA---YEGSKLL 2296 ++ +G + L +A+ G +E V+ L + + N GRT L AA+ G D V LL+ G++ D+ GR PL AATY V LLL + +I+ QD +G +A+ AA + +++ +KLL+ ++ I D EG L AA ++G KL Sbjct: 44 LNSEGMTPLFVAVSTGNLECVQFLATSGASLNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTIVDNCGRLPLHAATYYSSGRTVGLLLQHLPSDHINKQDGEGMTALHWAA--YHGRAEH---VKLLIDHDAEIVARDTEGKTALHWAAQVSHDGLKLF 200 HSP 5 Score: 56.6102 bits (135), Expect = 7.753e-9 Identity = 45/146 (30.82%), Postives = 67/146 (45.89%), Query Frame = 2 Query: 1622 IEATNVYSFS-LFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGR--TALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPL 2050 IEA N + LF ++ + + L +G +N + G T L +AA G+ LL+ GA+ ++D G L A + V LLL DG TAL AA+ GR + V LL+ + I +D+EG+T L Sbjct: 41 IEALNSEGMTPLFVAVSTGNLECVQFLATSGASLNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTIVDNCGRLPLHAATYYSSGRTVGLLLQHLPSDHINKQDGEGMTALHWAAYHGRAEHVKLLIDHDAEIVARDTEGKTAL 186 HSP 6 Score: 56.225 bits (134), Expect = 9.272e-9 Identity = 43/155 (27.74%), Postives = 74/155 (47.74%), Query Frame = 2 Query: 2828 DNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDF--GINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNH 3286 ++ G TPL ++V +C Q L + +N D+ GRT + +A+++G + + L+ VGA + DN GR LH + + LL+ +I++ +G TAL A+ G E LLI+ A + D+ +T A + +H Sbjct: 45 NSEGMTPLFVAVSTGNLECVQFLATSGAS-----LNTRDNLGRTPLALAAYQGWNDGVYYLLAVGADSTIVDNCGRLPLHAATYYSSGRTVGLLLQHLPSDHINKQDGEGMTALHWAAYHGRAEHVKLLIDHDAEIVARDTEGKTALHWAAQVSH 194
BLAST of Ankyrin repeat domain 50 vs. Ensembl Nematostella
Match: EDO49485 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG84]) HSP 1 Score: 88.5817 bits (218), Expect = 1.333e-19 Identity = 69/226 (30.53%), Postives = 105/226 (46.46%), Query Frame = 2 Query: 2252 MNMLLIAAYEGSKLLCKILLENNADI---DIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEG-QYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGS---TSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHS 2908 M L +A G CK LL D+ D DR+PL AA SGN + LL+ +CIDK G + L +A N + + L+ G + D CTPLH A+ +CV LL++ ++ D G + + G+ E L+DV + +S GS T L +A + +E L+ D ++D+ GRTPL ++ Q +C + LL H+ Sbjct: 1 MQPLHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASANGHKLAIEMLLDVSANDLLNRS-SGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLLNHN 225 HSP 2 Score: 80.1073 bits (196), Expect = 1.047e-16 Identity = 72/224 (32.14%), Postives = 112/224 (50.00%), Query Frame = 2 Query: 1751 LMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPL-MAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEG---MNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLL 2401 L +A GFT C LL G + D + + L A +G + ++LL+SQ D + GR L AA V+ L+++GSN+NK D++ TPL AA D V+ LL N +D G SA+ A+ +N L I++LL + N L + G + L +AA+ G K ++L+++ D+++ D R+PL A+F G+ E V LL Sbjct: 4 LHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYAS----ANGHKL-AIEMLLDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLL 222 HSP 3 Score: 75.8702 bits (185), Expect = 2.808e-15 Identity = 71/232 (30.60%), Postives = 104/232 (44.83%), Query Frame = 2 Query: 2546 PLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYD--GSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQS-QYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGR---TGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGA 3223 PLHLA + G EC LL G N DN+ R PL + G + E L+ ++ +F D G L A + V L++ G++ D TPLH + C + LL+ N N + D G +A+H AS G I+ L+DV A L + G T LHL A+ G ++LI +++ +G T L +AS +GH+E L+N A Sbjct: 3 PLHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMS---QAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLR-----NRGNASKRDKQGYSAVHYASANGHKLAIEMLLDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLLNHNA 226 HSP 4 Score: 75.0998 bits (183), Expect = 5.603e-15 Identity = 73/261 (27.97%), Postives = 114/261 (43.68%), Query Frame = 2 Query: 1850 LRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS-------PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGA 2611 L LA G+ E K LL +D + N+ RT L AA G + + LL+S + N D GR PL A ++ V L+ G+ ++ D + + AA ++ ++ LLR N + D +G + + A+ G KL ++LL+ +A+ D+++RS PL AAF G+ + +L+ F+ L + RD+ G TPL LAS +G ECV LL A Sbjct: 4 LHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAA----ASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASANGHKLAIEMLLDVSAN-DLLNRSSGSPCVTPLHLAAFHGHKPALEVLI-----------KSFNDLEV----------------------RDDRGRTPLDLASFQGHVECVECLLNHNA 226 HSP 5 Score: 63.5438 bits (153), Expect = 5.355e-11 Identity = 59/231 (25.54%), Postives = 99/231 (42.86%), Query Frame = 2 Query: 2645 PLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKG-DGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGA---TALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGAL 3325 PL L+C G+ + +KL+ + VN K + T L A + +E L+S+ D D GR PLH + + + C SL +N+N D T +H A+ D + ++ L+ +D +G + +H + G ++L+D N S G+ T L +A+ GH +LI ++ D RTP +A H++ L H A+ Sbjct: 3 PLHLACLGGFTECCKKLL-FYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCIDKLGRNPLHYAAGHTNFRCVM-----SLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASANGHKLAIEMLLDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLLNHNAM 227
BLAST of Ankyrin repeat domain 50 vs. Ensembl Nematostella
Match: EDO37520 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFL9]) HSP 1 Score: 90.8929 bits (224), Expect = 2.518e-18 Identity = 182/860 (21.16%), Postives = 323/860 (37.56%), Query Frame = 2 Query: 236 FKTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNL---CNYPDRAFKNGILLPLLS-FPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVR---KFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKD----DNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLS-IQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLF---KIKYFL-VKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAF----HLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFS-LFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGA---------YIDHQDNDGRSAIFV---------AALCLNSNSKYLDIIKLLLRYN-CNINLIDNEGMNMLLIAAYEGSKLLCKILLENN-------ADIDIVDRSP--------------------LMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLAR-GLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGA 2611 F + + +L H C +S + AKF+ + + S E +N N+++ Q L N P F +L PL PP+ M++++D++DE +L +T KN I +LLS + FP W+ ++ T +K + + + D+ N Y DI+ Y+ +++ + + + T E ++ L +S G +Y++++L+ + L + I +P + +Y+ + F ++F+ V+ I +++++ + L +IY + + ++D Y D+L ++ FL H+SL WL + + + +GH +LA Y I K + F H+ I K KG A LP E +L S + N+ L+ S + +T ++ + + + ++++ + S + F + N ++ L G ++ V + + A+N C L+ G+S L A G++E VK LL+ K+ D G T ++ AA GR ++ +L G+ + + PL +A V+ L G I R V AL + S + DI+ +LR N + D GM L A S K LE A +++ P L AA G ++ LL +GA D G + ++A +LS L+A +D RD G TP H A + L K GA Sbjct: 409 FSSYSMNIRVLGYHMCISSYRSTKEPAKFVRSVAAMI--SSVIKEYSYITLN-----NIYIQQKLDTCVNDPVDCFDQVVLSPLRHILDPPSNQMFLVVDALDECIL--------------ETGRKN-----EIVELLSKTLDQFPSWVKVLLTSQKVPSILTEFSSPHVSLVEIEQDNPNNLY---DIEQYVSHKLYEQSTVWSRMVSFLTGNTDERISSLIKRSEGNFLYIKVMLEYMQTEKLQGPEQINDVPKSVHRIYMSYLKRHFTE-EEFVPVRRILKVLVAAYEPLLTTDIYHVIRAKNQSSDSNYYYDILRTLDRLSMFLHFSRQRETVQVFHSSLSVWLTSNETLGGPFYVNRSNGHQSLAEYFLSIVEKNSQRFGYRLGFYLANHIFEGGTIAKHKGRFLA---------------LPSE---------------LLNSSDSTTNMTALHFAASTS--NTGVIGLLANHFSTVDCLDRNSRTPAFIAASTGQKNILAILFQKGANLFHVTNSLSKKHQQRAKNPVKD-CKRLMC-----------GYSLLHAAAQGGHVETVKFLLNHKLSKDAESGAGNTPMQIAAQYGRVSVMEVLHKHGAPCDPR------PLRSAAAGGHLPAVRFLHQAGVSDECVPCKYSISPSYMKQRVGKLVDDEYLWRCETALHIASAMEQPDIVSYILRSNDTALTCYDYLGMRPLHKAVVYNSIKSLKAFLEYGVSPLSRCAPAEVLSTYPEDKYKNIADYFEPCICRYNALHLAARHGRVNMIATLLEYGAKTGVFDACGSQAVHVAACYDQVGVLSLLVAEYKVDVNSRDLIGKTPFHYAVKCKAAGALKRLFKLGA 1188
BLAST of Ankyrin repeat domain 50 vs. Ensembl Nematostella
Match: EDO38702 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC57]) HSP 1 Score: 85.8853 bits (211), Expect = 2.679e-17 Identity = 102/439 (23.23%), Postives = 180/439 (41.00%), Query Frame = 2 Query: 1745 TSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLS--------QKIDPDFTGNDG--RTALRTAAWIGRTDIVLLLLSSGSNINK-QDSEGRT--PLMAATYKCDYVMVKL-------------------------------LLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAAAFSGNFEVV-------RLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMH-RDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQH 2905 T L VA +G + L+ +GA+ +D++ + L A G + V KLL + T D +TAL A G D+ L L G+N+N ++S+ +T + +C +VM+K+ ++ A I+ +D D + + +AA ++D ++ LL++ +I D N + AA EG + LE+ + + + G+ +++ +LLL GA I + + + +A G + + LL R ++ D TPLHLA++ G V LL G + + PL + G +++A L+D V+ +T L +A E V+ LLSR A+ T+ D+ GR L I++ S + ++ H Sbjct: 6 TPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKSEKIKREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAA-----EKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLD-EDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIIDH 438 HSP 2 Score: 83.1889 bits (204), Expect = 2.058e-16 Identity = 112/470 (23.83%), Postives = 197/470 (41.91%), Query Frame = 2 Query: 1943 TALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLL-----LNNG-----AYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLID---NEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLID----VWP--ESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKI 3295 T L A G + L+ +G+++ D E TPL A + + + KLL L G + QD + ++A+ +A + D+ KL L N+N + N+ + ++ A E ++ K+ S L +F + ++ R +L + F V+ I I + R E RD TPL +A+ + + V LL+ GA D + R + + EG ++ E ++ VW + V G ++ I VL R+ + LL GA +++ TP+H + + LL+ + IN D T +H+A+ G ++K L+ G ID ++ T L A +G ++ +L+D +D T T L +AS+EGH+E+ LL++ AN+ DS R +A + +H ++ Sbjct: 6 TPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREEQTALHLAV-----EGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKV-------------SKLKYLSFCKSEKIKREILLYF----------FDVVII--------ICYIIRFRACIEC-RDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVL-RISS--QLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKR----DPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEV 431 HSP 3 Score: 83.1889 bits (204), Expect = 2.058e-16 Identity = 108/453 (23.84%), Postives = 189/453 (41.72%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLS--------SGANQLMIDKDG--WSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRT-------------------------------DIVLLL---LSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA------------------------LCLNS----NSKYLDIIK----LLLRYNCNINLIDNEGMNMLLIAAYEGS-KLLCKILLENNA---DIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDV--WPESVNFKSYDGS--TSLKIAVLNRLPEFVEFLLS 2803 L+ G D+ ++E T L A G + LL S ++++ D+D +AL LA+ G+ ++ KL L + + + + R D+V+++ + + I +D + TPLM A K V+ LL +GA I +D + R+++F AA +CLN ++K + +++ LLL I+ ++E + + AA G + +C +L + A D D +PL AA G+ VV+ LL+ G AI + + ++ L +A++G ++ + LL D TPLHLAS EG E V LLL A D+ GR L ++ + + ++A +ID W +++ + G+ TS ++ +LP +LL Sbjct: 23 LVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKSEKIKREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIIDHVDWKQAMRNRCKLGNAITSPMRKLIKKLPGQKLYLLQ 475 HSP 4 Score: 56.9954 bits (136), Expect = 3.023e-8 Identity = 53/160 (33.12%), Postives = 80/160 (50.00%), Query Frame = 2 Query: 1691 SQLII-NGLDINCVNENGTTSLMVAAQNG-FTSICNLLLSSGANQLMIDKDGWS--ALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVA 2158 SQL++ NG I+ N+ T + AA+ G ++C LL A ++ D+DG S L LA +G+ VVK LL + D T L AA G ++ +LL + ++ D TPL A+ + MVKLLL+ A I D+ GR+ + +A Sbjct: 266 SQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPA--IINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIA 423 HSP 5 Score: 55.8398 bits (133), Expect = 8.445e-8 Identity = 93/410 (22.68%), Postives = 156/410 (38.05%), Query Frame = 2 Query: 2252 MNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDN------HGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVE---FLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKS-------------------------------------LIDVGARIDLKDNEGRTGLHLGAWQG-CYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 M L +A G + K L+E AD+ +D +PL A GN V +LL F A + + G+S +S + +D T LHLA G + L L+ GA N + H I + C IK+++ + + S+ S +K +L + V +++ A +D + TPL I+ ++ D + LLQH +I D + R ++ A+ +G E +++ L+D GA ID K++E T +H A G +C LL I++ T L +A+ GH + L+ G + ++ + TP A +++ N+L A VD Sbjct: 5 MTPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLL-FVAAEL----RGGWSTVSKMVTD------------------QDREEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSK---------LKYLSFCKSEKIKREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHG-----ADIAAKDINDRNSVFRAAAEGCMETLEAALEHQKPVWTICDDVCLNGLVGGSNKLILVLRISSQLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVD 377 HSP 6 Score: 49.2914 bits (116), Expect = 8.120e-6 Identity = 32/91 (35.16%), Postives = 45/91 (49.45%), Query Frame = 2 Query: 1688 ISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTA 1960 + +L+ G I+ N T L AA G + N+LL A DK + L LA G++E+VKLLLS+K + T + GR L A Sbjct: 333 VKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIA 423
BLAST of Ankyrin repeat domain 50 vs. Ensembl Nematostella
Match: EDO34863 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN65]) HSP 1 Score: 80.1073 bits (196), Expect = 4.171e-17 Identity = 54/161 (33.54%), Postives = 82/161 (50.93%), Query Frame = 2 Query: 2744 TSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSL-THNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNE-GRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFG 3220 T L IAV+ P+ V+ L+ GA+ + D NG+TP H++ +S C L SL +NI N +G +HIA K D I L+ GA +D KD + G+T LH + QI + L+D +I+ T G + +++A++ G LL N G Sbjct: 15 TPLHIAVITDQPDIVKCLIYAGANPNLPDRNGQTPAHLACQRSAVRCLYELTSSSLLDYNIRNF-----EGLMPLHIAVAKRDKYAIALLVQNGANVDCKDGKSGKTPLHHAIERNDLQIIKTLLDMSADINATDFSGVSPMAMANRRGLANAVRLLGNRG 170 HSP 2 Score: 75.0998 bits (183), Expect = 2.268e-15 Identity = 50/173 (28.90%), Postives = 87/173 (50.29%), Query Frame = 2 Query: 2528 DNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQD-NNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVG--ARIDL 3037 +N TPLH+A + Q + V L+ +GA PN D +G+ P L+CQ ++ +L N ++++G L IAV R + L+ GA+ +D +G+TPLH ++ ++ + LL S +IN D G + + +A+ +G ++ L + G R+DL Sbjct: 10 NNLRQTPLHIAVITDQPDIVKCLIYAGANPNLPDRNGQTPAHLACQRSAVRCLYELTSSSLLDYNIRNFEGLMPLHIAVAKRDKYAIALLVQNGANVDCKDGKSGKTPLHHAIERNDLQIIKTLLDMSA-----DINATDFSGVSPMAMANRRGLANAVRLLGNRGEDQRVDL 177
BLAST of Ankyrin repeat domain 50 vs. Ensembl Medaka
Match: ankrd50l (ankyrin repeat domain 50 [Source:NCBI gene;Acc:101161928]) HSP 1 Score: 588.186 bits (1515), Expect = 0.000e+0 Identity = 364/1068 (34.08%), Postives = 571/1068 (53.46%), Query Frame = 2 Query: 266 LASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDY-LGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEK------FGSLNDWSIDDIVKILFESINLVN--INKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLF-----ESIRQ--------NSYNTISQLII-NGLDINCVNENGTTSLMVAAQNGFTSICNLLL-------SSGANQLM--IDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS---KYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID-----------IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSG--AKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDF-GINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 LASHFC D S L +F+ + + L S + Y ++ + + + PD FK +L PLL PPP + + ++ID++D DY GE + S +I++LL+ + + P WL LVC+ R++N+ + + F GFRK LDDL K +RD+Q YIL R+DKD L++ + +T ++LNLLHIKS G ++LE VLDG+ + ++ I+ IPG L GLYLW+ + LF + F V+ + N++L+S K L+ +++ A+ D + + ++ L + L+ H S EWL DVK CT KY C +GH LA+ L A HL+ S K K A+W+L++D V + P L ++ ++L S +++ +++ + K ++ + + + T + L + RQ + + +++L++ +G D + G T + +A+ G + +LLL A Q+M D +GW+ALR A W G+ E V LLL D + ++GRTALR AAW G +IV LL G+ +NK DS+GRTPL+AA Y + V++LLN+ A +D D DGR+A+ VAALC+ + + + ++ LLL +N + DN+GM LL+AAYEG + + ++LLE AD+D +PL+A+A G+ + V LLFWGAA+ ID G + L ++A++G+ +++ LL RGLDE H+D+ G TPLH A+ EG L + G A+ E+D GR PL+L+ QEG+ + L+D ++ ++YDG ++L A L + E L+ RGAD ++D GR L++ VL+ + +L++ + D +GRTA+H+ASW+G EI+ L+ GA+ + +D+EGR LH AW G ++ + L++ GI+++ C QGATALSIASQEGH I +L+ G+N H+D R+P KVA K H I LLE +GA Sbjct: 86 LASHFCQREDQRSTVLWRFVLGLVEQLRASPFLSSGYEDILSRESVVSALEPLSCQRSPDETFKRAVLQPLLELPPPAQTLMVVIDALD----VDYEPGEGVGK-------------SDSIAELLATNQHLLPSWLLLVCSVRRQNKAVCKMFSGFRKLCLDDLRKPPAVRDVQQYILCRLDKDAALRRQLTPDTADMLNLLHIKSGGCFLFLERVLDGVAAALVGLREIRDIPGTLNGLYLWLCQRLFPR-RLFAHVRPLLNVLLASPKPLTSLQLFTAVWTQDTSLSIQDFQNKLQTLSPLLISGPGCTKLLFHASFAEWLTDVKYCTQKYLCGRSEGHTMLAMALTLRGPDLDADSTCQLAAHLVCSG-HHKDKPSLLALWMLWAD----VPALPPSSSTALTTSLAQLPALVSQNVPQLLMRSGVILSGCLSEPDIKVGMLSLCEEGADLQQPFDSGLSVTKLLDCGLSVDQLGPADRQTLLAKAALDGFEKVAELLLKHGSDPLICDHQGQTPMTLASSQGHVKVLSLLLEWAKGQGPQTAAQMMEHADNEGWTALRSAAWGGHKEAVGLLLDAGADVNGCDSEGRTALRAAAWGGHEEIVFTLLDYGAQVNKADSKGRTPLIAAAYMGHHETVEVLLNHNAEVDLADGDGRTALSVAALCVPTAAGVQGFGEVASLLLEHNADPGHRDNDGMTPLLLAAYEGHEDVVELLLEAGADVDETAGLDGSVSAAAAVTPLLASAAMGHMKTVSRLLFWGAAVDAIDCEGRTALCLAAARGSLEVVRALLDRGLDENHKDDLGWTPLHAAACEGHRAVCAALTEHGSMARVGEMDIEGRTPLILAAQEGHWSTVKILLDRR-SPIDHRAYDGHSALSAAFLEGHTDVAELLMKRGADTDVRDAEGRPLLYLLVLEDHLNMASLLIEKGGV----PLESRDSEGRTALHVASWRGTVEIVDLLLKHGAKPNAQDSEGRPPLHSVAWTGHAKVGRRLLETDGIDVNLACHQGATALSIASQEGHANIVKMLLEKGSNPNHLDKYGRSPVKVAAKHGHFTIVRLLESYGA 1125 HSP 2 Score: 130.954 bits (328), Expect = 3.837e-30 Identity = 105/353 (29.75%), Postives = 169/353 (47.88%), Query Frame = 2 Query: 1709 GLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGS--NINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEG------------MNM----------------------LLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFW-GAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIP 2647 GLD + T L+ +A G + LL GA ID +G +AL LA G +EVV+ LL + +D + + G T L AA G + L GS + + D EGRTPL+ A + + VK+LL+ + IDH+ DG SA+ A L + D+ +LL++ + ++ D EG +NM L +A++ G+ + +LL++ A + D R PL + A++G+ +V R LL G ++ G + LSI++ +G++ I+ LL +G + H D +G +P+ +A+ G + V LL GAKP HG +P Sbjct: 790 GLDGSVSAAAAVTPLLASAAMGHMKTVSRLLFWGAAVDAIDCEGRTALCLAAARGSLEVVRALLDRGLDENHKDDLGWTPLHAAACEGHRAVCAALTEHGSMARVGEMDIEGRTPLILAAQEGHWSTVKILLDRRSPIDHRAYDGHSALSAAFL-----EGHTDVAELLMKRGADTDVRDAEGRPLLYLLVLEDHLNMASLLIEKGGVPLESRDSEGRTALHVASWRGTVEIVDLLLKHGAKPNAQDSEGRPPLHSVAWTGHAKVGRRLLETDGIDVNLACHQGATALSIASQEGHANIVKMLLEKGSNPNHLDKYGRSPVKVAAKHGHFTIVRLLESYGAKP----YHGTVP 1133 HSP 3 Score: 124.405 bits (311), Expect = 3.918e-28 Identity = 106/353 (30.03%), Postives = 166/353 (47.03%), Query Frame = 2 Query: 2336 VDRSPLMA-AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELL--ARGLDEM-------HRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVL----QSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARID--------LKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALV 3328 DR L+A AA G +V LLL G+ D G + +++++SQG+ ++LS LL A+G H DN G T L A+ G E V LLL +GA N D+ GR L + G+ +I L+D + VN G T L A E VE LL+ A+ + D +GRT L ++ L + F + L HN + + D+DG T + +A+++G ++++ L++ GA +D + T L A G + L+ +G +D +G TAL +A+ G LE+ L++ G + H D TP A H +C L +HG++ Sbjct: 542 ADRQTLLAKAALDGFEKVAELLLKHGSDPLICDHQGQTPMTLASSQGHVKVLSLLLEWAKGQGPQTAAQMMEHADNEGWTALRSAAWGGHKEAVGLLLDAGADVNGCDSEGRTALRAAAWGGHEEIVFTLLD-YGAQVNKADSKGRTPLIAAAYMGHHETVEVLLNHNAEVDLADGDGRTALSVAALCVPTAAGVQGFGEVASLLLEHNADPGH-RDNDGMTPLLLAAYEGHEDVVELLLEAGADVDETAGLDGSVSAAAAVTPLLASAAMGHMKTVSRLLFWGAAVDAIDCEGRTALCLAAARGSLEVVRALLDRGLDENHKDDLGWTPLHAAACEGHRAVCAALTEHGSMA 892 HSP 4 Score: 82.0333 bits (201), Expect = 2.869e-15 Identity = 66/216 (30.56%), Postives = 94/216 (43.52%), Query Frame = 2 Query: 2690 KLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASW-KGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPY-KVAYKGNHIKICNLLEKHGALVD 3331 KL+D D T L A L+ + E LL G+D I D+ G+TP+ ++ Q +LL+ W KG G + + ++ DNEG T L AW G + LL+D G +++ S+G TAL A+ GH EI L+++GA V DS RTP AY G+H + +L H A VD Sbjct: 528 KLLDCGLSVDQLGPADRQTLLAKAALDGFEKVAELLLKHGSDPLICDHQGQTPMTLASSQGHVKVLSLLLE-------------------------WAKGQGPQTAAQM-----MEHADNEGWTALRSAAWGGHKEAVGLLLDAGADVNGCDSEGRTALRAAAWGGHEEIVFTLLDYGAQVNKADSKGRTPLIAAAYMGHH-ETVEVLLNHNAEVD 712 HSP 5 Score: 52.373 bits (124), Expect = 4.099e-6 Identity = 26/74 (35.14%), Postives = 43/74 (58.11%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDP 1918 L +G+D+N G T+L +A+Q G +I +LL G+N +DK G S +++A +G+ +V+LL S P Sbjct: 1054 LETDGIDVNLACHQGATALSIASQEGHANIVKMLLEKGSNPNHLDKYGRSPVKVAAKHGHFTIVRLLESYGAKP 1127 HSP 6 Score: 51.6026 bits (122), Expect = 7.221e-6 Identity = 39/140 (27.86%), Postives = 72/140 (51.43%), Query Frame = 2 Query: 2948 DGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGIN---------IDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 D +T + A+ G ++ + L+ G+ + D++G+T + L + QG ++ LL+++ ++ ++G TAL A+ GH E LL++ GA+V DS RT + A G H +I L +GA V++ + Sbjct: 543 DRQTLLAKAALDGFEKVAELLLKHGSDPLICDHQGQTPMTLASSQGHVKVLSLLLEWAKGQGPQTAAQMMEHADNEGWTALRSAAWGGHKEAVGLLLDAGADVNGCDSEGRTALRAAAWGGHEEIVFTLLDYGAQVNKAD 682
BLAST of Ankyrin repeat domain 50 vs. Ensembl Medaka
Match: ENSORLT00000031565.1 (ankyrin 2 [Source:NCBI gene;Acc:101161458]) HSP 1 Score: 215.698 bits (548), Expect = 3.247e-56 Identity = 158/564 (28.01%), Postives = 270/564 (47.87%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S + R + + + + + G+DI+ N+NG +L +AA+ G + LL GA K G +AL ++ G EVVK L+ + D + +G T L AA D+V LL +G N + +G TPL A + +V +LL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +VRLLL G+ I + G + L +A G+ + LL +G + R G +PLH+A+ ECV LL+ A +++ L ++ G+ ++ + L+D + N ++ +G T L IA + +E L+ GA +G TP+H++ + +LLQ+ + +++NI G T++H+A+ G E+++ L+ GA +D + E +T LH+ + G +I QLL+ + D + G T L I+++EG LE ++L+ GA+ TP V K + + LL + A D Sbjct: 50 SFLRAARAGNIDKVLEYLKGGVDISTCNQNGLNALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILL---------ENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKR-ANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIR-----GETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPD 598 HSP 2 Score: 207.994 bits (528), Expect = 8.628e-54 Identity = 168/555 (30.27%), Postives = 253/555 (45.59%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 ++ + N + L+ G I+ +G T L AA++G + +LL GA L K+G S L +A ++E VK LL K D D TAL AA G + LLL +N N + G TPL A K +++LL+ GA I G + I VAA +L+I+ LLL+ + ++ + G L +AA G + + LL N A +D D++PL A+ G E+V+LLL A +G++ L ISA +G + S LL G G TPLH+ S G + LLL+ A P+ +G PL ++ YD K+A+L LL +GA NG TPLHI+ ++Q D VLLQ+ N L G T +H+AS +G ++ L+ GA+I++ G T LHL A + + ++L+ G N+D G T L +A G+ ++ + L+ GA+V TP A + + I N+L +HGA Sbjct: 283 KRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFM-----GHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAH----------------------YDNQ---KVALL---------LLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGA-----ETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGA 793 HSP 3 Score: 197.208 bits (500), Expect = 1.728e-50 Identity = 173/622 (27.81%), Postives = 278/622 (44.69%), Query Frame = 2 Query: 1652 LFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICN-----------------------------LLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 L+ + ++N + + L+ NG + + E+G T L +A Q G + + LLL + N + K G++ L +A G + V LLL++ DFT +G T L A+ G T++V LLL GS I+ + +G TPL A V++LL GA + + +G S + +AA L + ++ + + KLLL N N G L IA + + ++L++ A I V S P+ AAF G+ +V LLL GA+ + G + L ++A G ++++ LL G R TPLH+AS G+ E V LLL+ A P+ +G PL +S +EG ++ A L++ S + + G T L + + + LL R A NG TPLH++ + YD +V L L + + +G T +HIA+ K +I L+ GA + +G T LHL + +G + LL+ G I+ G TAL +A+QE + + +L+ GAN+ H TP VA + K+ + L ++GA V+ K Sbjct: 150 LYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAG-ASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVA---AHYDNQKVALL--LLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAK 765 HSP 4 Score: 171.785 bits (434), Expect = 1.384e-42 Identity = 129/428 (30.14%), Postives = 206/428 (48.13%), Query Frame = 2 Query: 1736 NGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 NG T L +A + + LL+ GA+ + + G + + +A + G++ +V LLL PD + G T+L AA G+ ++V LL +G+ ++ + E +TPL A+ +V+LLL + A+ D +G + + ++A L+ +LL + +L +G L + + GS + K+LL+ A D + +PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G + G TPLHLAS EG + LL+ GA+ N G L L+ QE + +AE L+ +++ ++ G T L +A + V FLL GA + NG TPLH + Q VLLQH N +N G TA+ IA G ++ +L Sbjct: 405 NGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISA-----REGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNG-ANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVN-----GNTALGIARRLGYISVVDTL 821 HSP 5 Score: 135.961 bits (341), Expect = 1.224e-31 Identity = 111/417 (26.62%), Postives = 187/417 (44.84%), Query Frame = 2 Query: 1547 KLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMID---KDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 K N K + Y +I + + + +V +F N + L+ NG + N G TSL +AA+ G + LL +GA M+D ++ + L +A G E+V+LLL PD +G T L +A G+ + +LL +G++ + +G TPL + + KLLL A D +G + + VAA L + + +DI +LL+Y N + +G+ L +A+ EG + +L+ A I++ +S L A AA V +L+ GA + K G++ L ++ GN++++S LL G + G TPLH A+ +G +N+LL+ GAKPN + +G L ++ + GYI + + L Sbjct: 415 KKNRVKVMELLVKYGASIQAVTESGLTPIHVAAF-------MGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGA---MVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVNGNTALGIARRLGYISVVDTL 821 HSP 6 Score: 129.413 bits (324), Expect = 1.236e-29 Identity = 105/398 (26.38%), Postives = 187/398 (46.98%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L + ++D+++ LL ++ +G L I++ G + K L++ ADI+ + +PL AA + +VVR LL G + GF+ L+I+ QG++Q++S LL + LH+A+ + + LLL++ + G PL ++ G + +A L++ +V+F + +G T L +A V LL RG+ + +G TPLH + +VLL+ + +G + +H+A+ E +K L+ A +D + T LH+ A G Y++ +LL+D N + G T L IA ++ +++ LL+ +GA++ + TP VA H+ I LL ++GA D N+ Sbjct: 83 ALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDT----KGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRG-AAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAP-----LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNI 470
BLAST of Ankyrin repeat domain 50 vs. Ensembl Medaka
Match: ENSORLT00000039458.1 (ankyrin 2 [Source:NCBI gene;Acc:101161458]) HSP 1 Score: 215.312 bits (547), Expect = 4.634e-56 Identity = 158/564 (28.01%), Postives = 270/564 (47.87%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 S + R + + + + + G+DI+ N+NG +L +AA+ G + LL GA K G +AL ++ G EVVK L+ + D + +G T L AA D+V LL +G N + +G TPL A + +V +LL +ND + + + AL + + LLL+ + N ++ G L IAA+ G+ + +LL A +D R +PL A+ GN +VRLLL G+ I + G + L +A G+ + LL +G + R G +PLH+A+ ECV LL+ A +++ L ++ G+ ++ + L+D + N ++ +G T L IA + +E L+ GA +G TP+H++ + +LLQ+ + +++NI G T++H+A+ G E+++ L+ GA +D + E +T LH+ + G +I QLL+ + D + G T L I+++EG LE ++L+ GA+ TP V K + + LL + A D Sbjct: 35 SFLRAARAGNIDKVLEYLKGGVDISTCNQNGLNALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILL---------ENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKR-ANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIR-----GETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPD 583 HSP 2 Score: 207.608 bits (527), Expect = 1.054e-53 Identity = 168/555 (30.27%), Postives = 253/555 (45.59%), Query Frame = 2 Query: 1667 RQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 ++ + N + L+ G I+ +G T L AA++G + +LL GA L K+G S L +A ++E VK LL K D D TAL AA G + LLL +N N + G TPL A K +++LL+ GA I G + I VAA +L+I+ LLL+ + ++ + G L +AA G + + LL N A +D D++PL A+ G E+V+LLL A +G++ L ISA +G + S LL G G TPLH+ S G + LLL+ A P+ +G PL ++ YD K+A+L LL +GA NG TPLHI+ ++Q D VLLQ+ N L G T +H+AS +G ++ L+ GA+I++ G T LHL A + + ++L+ G N+D G T L +A G+ ++ + L+ GA+V TP A + + I N+L +HGA Sbjct: 268 KRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFM-----GHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAH----------------------YDNQ---KVALL---------LLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGA-----ETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGA 778 HSP 3 Score: 196.823 bits (499), Expect = 2.527e-50 Identity = 173/622 (27.81%), Postives = 278/622 (44.69%), Query Frame = 2 Query: 1652 LFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICN-----------------------------LLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 L+ + ++N + + L+ NG + + E+G T L +A Q G + + LLL + N + K G++ L +A G + V LLL++ DFT +G T L A+ G T++V LLL GS I+ + +G TPL A V++LL GA + + +G S + +AA L + ++ + + KLLL N N G L IA + + ++L++ A I V S P+ AAF G+ +V LLL GA+ + G + L ++A G ++++ LL G R TPLH+AS G+ E V LLL+ A P+ +G PL +S +EG ++ A L++ S + + G T L + + + LL R A NG TPLH++ + YD +V L L + + +G T +HIA+ K +I L+ GA + +G T LHL + +G + LL+ G I+ G TAL +A+QE + + +L+ GAN+ H TP VA + K+ + L ++GA V+ K Sbjct: 135 LYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAG-ASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVA---AHYDNQKVALL--LLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAK 750 HSP 4 Score: 171.014 bits (432), Expect = 2.092e-42 Identity = 129/428 (30.14%), Postives = 206/428 (48.13%), Query Frame = 2 Query: 1736 NGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSL 3010 NG T L +A + + LL+ GA+ + + G + + +A + G++ +V LLL PD + G T+L AA G+ ++V LL +G+ ++ + E +TPL A+ +V+LLL + A+ D +G + + ++A L+ +LL + +L +G L + + GS + K+LL+ A D + +PL AA N +V LLL GA+ H K+G++ L I+A + I + LL G + G TPLHLAS EG + LL+ GA+ N G L L+ QE + +AE L+ +++ ++ G T L +A + V FLL GA + NG TPLH + Q VLLQH N +N G TA+ IA G ++ +L Sbjct: 390 NGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISA-----REGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNG-ANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVN-----GNTALGIARRLGYISVVDTL 806 HSP 5 Score: 135.576 bits (340), Expect = 1.560e-31 Identity = 111/417 (26.62%), Postives = 187/417 (44.84%), Query Frame = 2 Query: 1547 KLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMID---KDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA----------------------------LCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKL 2695 K N K + Y +I + + + +V +F N + L+ NG + N G TSL +AA+ G + LL +GA M+D ++ + L +A G E+V+LLL PD +G T L +A G+ + +LL +G++ + +G TPL + + KLLL A D +G + + VAA L + + +DI +LL+Y N + +G+ L +A+ EG + +L+ A I++ +S L A AA V +L+ GA + K G++ L ++ GN++++S LL G + G TPLH A+ +G +N+LL+ GAKPN + +G L ++ + GYI + + L Sbjct: 400 KKNRVKVMELLVKYGASIQAVTESGLTPIHVAAF-------MGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGA---MVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQRQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLHLASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVNGNTALGIARRLGYISVVDTL 806 HSP 6 Score: 129.028 bits (323), Expect = 1.536e-29 Identity = 105/398 (26.38%), Postives = 187/398 (46.98%), Query Frame = 2 Query: 2159 ALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 AL L + ++D+++ LL ++ +G L I++ G + K L++ ADI+ + +PL AA + +VVR LL G + GF+ L+I+ QG++Q++S LL + LH+A+ + + LLL++ + G PL ++ G + +A L++ +V+F + +G T L +A V LL RG+ + +G TPLH + +VLL+ + +G + +H+A+ E +K L+ A +D + T LH+ A G Y++ +LL+D N + G T L IA ++ +++ LL+ +GA++ + TP VA H+ I LL ++GA D N+ Sbjct: 68 ALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDT----KGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRG-AAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAP-----LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNI 455
BLAST of Ankyrin repeat domain 50 vs. Ensembl Medaka
Match: ank1a (ankyrin-1 [Source:NCBI gene;Acc:101174837]) HSP 1 Score: 214.927 bits (546), Expect = 4.721e-56 Identity = 169/598 (28.26%), Postives = 277/598 (46.32%), Query Frame = 2 Query: 1688 ISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPD-----------FTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADID---IVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYEC---------------------------------VNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKN 3340 +++L+ G ++N ++ G T L +AAQ + LL +GANQ + +DG++ L +A+ G+ VV LL+S F G T L AA ++ LLL+ G+N + TPL A + ++++LL+NGA I + +G S I +AA ++D +K LL+YN I+ I + + L +AA+ G + K+LL+ A + + +PL A + V+ LLL A+I + +SG + L +++ G+ I+ LL +G + TPLH+AS G +E V LLL+ A PN G PL ++ +EG+++ L+D+ + + G T L +A + E LL RGA+ NG TPLH++V + D +L+ + + +G TA+HIA+ + E+ SL+ GA + + +G T LHL + +G I LLI N++ G T L + +QEGH+ I ++L+ GA+V TP VA +IK+ L + A V+ K Sbjct: 89 VTELVNYGTNVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLISYGTKGKVRLPALTDFCFFLSVTGFTPLHIAAHYENLNVAQLLLNRGAN------DELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAA-----QGDHMDCVKQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQNAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKM-TKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKG-----GSPHSAARNGYTALHIAAKQNQVEVANSLLQHGASANAESLQGVTPLHLASQEGRPDIVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANVNSKT 669 HSP 2 Score: 190.274 bits (482), Expect = 2.033e-48 Identity = 154/571 (26.97%), Postives = 262/571 (45.88%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINL-----------IDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLA--RGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGA 3322 S + R + + + I NG+DIN N+NG +AL LA G++++V LL I + T G TAL AA G+ +V L++ G+N+N Q +G TPL A + +VK LL NGA DG + + VA + +++ LL+ Y + + G L IAA+ + + ++LL A+ ++ +PL AA +G+F ++ +LL GA I K+G S + ++A + + +LL +D++ D+ TPLH+A+ G + +LL GAKPN +G PL ++C++ ++++ + L+ S+ + G T L +A V+ LL +GA + + TPLH++ ++ + LLQ N ++ D +T +H A+ G E++K L++ A + G + LH+ A +G Q +LL+D + +G T L +AS+ G +++ LL+ GAN TP VA N++ + NLL G Sbjct: 10 SFLRAARSGNLDKALEHIKNGIDINTANQNG---------------------------------LNALHLASKEGHVKMVLELLHNGIVLETTTKKGNTALHIAALAGQEQVVTELVNYGTNVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVAL-----QQGHENVVALLISYGTKGKVRLPALTDFCFFLSVTGFTPLHIAAHYENLNVAQLLLNRGANDEL---TPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQLLQYNAEIDDITLDHL--TPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLK-HSASIEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQ-----NAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGG 531 HSP 3 Score: 157.532 bits (397), Expect = 2.534e-38 Identity = 129/477 (27.04%), Postives = 217/477 (45.49%), Query Frame = 2 Query: 1922 FTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHC-----------IDKSGFSVLSISASQGNSQILSELLARGL-DEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 ++ + G + LR AA G D L + +G +IN + G L A+ + MV LL+NG ++ G +A+ +AAL ++ L+ Y N+N +G L +AA E + K LLEN A+ I +PL A G+ VV LL+ +G + +GF+ L I+A N + LL RG DE+ TPLH A+ G + + +LL +GA +G P+ ++ Q ++ ++L+ E ++ + D T L +A + LL +GA + NG TPLHI+ ++ +LL+HS + I + + G T +H+AS+ G I+K L+ GA + + T LH+ + G +++ + L+ +D T L A++ GH E+ LL+ AN + +P +A + H++ LL Sbjct: 3 YSADAGNSFLR-AARSGNLDKALEHIKNGIDINTANQNGLNALHLASKEGHVKMVLELLHNGIVLETTTKKGNTALHIAALAGQEQ-----VVTELVNYGTNVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLISYGTKGKVRLPALTDFCFFLSVTGFTPLHIAAHYENLNVAQLLLNRGANDEL-------TPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQLLQYNAE-IDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSAS-----IEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQNAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLL 460 HSP 4 Score: 106.301 bits (264), Expect = 1.393e-22 Identity = 78/310 (25.16%), Postives = 143/310 (46.13%), Query Frame = 2 Query: 1589 ILNITSTYSNSIEATNV-YSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLAR 2506 I+ I S A+NV L + R + L+ N ++ ++ T L AA+ G + LLL AN G S L +A G+++ V+LLL + G T L A+ G+ D+ LLL G+N N G TPL A + + +V LL++ G +G +A+ +AA +++ LL++ + N +G+ L +A+ EG + +L+ A++++ ++S PL A G+ + +L+ GA+++ + G++ L ++ GN +++ LL + Sbjct: 357 IVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQNAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTALHIAA-----KQNQVEVANSLLQHGASANAESLQGVTPLHLASQEGRPDIVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQ 661 HSP 5 Score: 64.3142 bits (155), Expect = 7.978e-10 Identity = 43/157 (27.39%), Postives = 73/157 (46.50%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYID 2119 L ++ N+ + ++ L+ G + NG T+L +AA+ + N LL GA+ G + L LA G ++V LL+S++ + + G T L A G I +L+ G+++ G TPL A + + MVK LL A ++ Sbjct: 510 PLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTALHIAAKQNQVEVANSLLQHGASANAESLQGVTPLHLASQEGRPDIVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANVN 666
BLAST of Ankyrin repeat domain 50 vs. Ensembl Medaka
Match: ankrd44 (ankyrin repeat domain 44 [Source:NCBI gene;Acc:101173198]) HSP 1 Score: 208.379 bits (529), Expect = 1.674e-54 Identity = 185/678 (27.29%), Postives = 306/678 (45.13%), Query Frame = 2 Query: 1496 DDIVKILFESINLVNINKLNAKKSFTIFS---------TYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPD-FTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLC-KILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVE---------------------------------GQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRL-----------------------PEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCS-QGATALSIASQEGHLEICNLLINF--GANVCHI-DSCMRTPYKVAYKGNHIKICNLL 3307 ++I ++++S +IN L+A+K + + T +L ++ N+ + N++ L ++ S + + LI + D+N ++N T L VAA N +++ + + D+ G +AL A NG+ E+V LLL++ + + F DGR AL AA++G D+V +L+S G+ ++ +D G TPL AA +VK LL+ ID + G +A+ +A C N ++ L+ Y N++ +N+G L AA LC + L+ N ADI+I R SPL A G F + L+ G I+ +DK G + L ++A G+ +++ L+ G D R G PLHLA++ G +CV LLLKSG + N D GR PL + + E L+ V +N G ++L A + L + +EFLL GA A ++D G +P+H + C ++LL TH+ + ++ +H+A++ G + ++ L+ G +D +D GRT L L A +G L+ G + T G T + +A GH LL++ GA V + D RTP +A G H+ +LL Sbjct: 22 EEIRMLIYKS---EDINVLDAEKRTPLHAAAFLGDAEITELLILSGARVNAKD--NMWFTPLHRAVASRSQDAVQVLIRHSADVNARDKNWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGR-ALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLA--CFNGQDA---VVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGADINIQSRDGKSPLHMTAVHGRFTRSQTLIQNGGEINSVDKDGNTPLHVAARYGHELLINTLITSGADCARRGVHGMFPLHLAALNAHSDCCRKLLSSGFQIDTPDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYAAASRHYHCLETLV-VCGTDINATDQWGRSALHYAAASDLDRRRRVALEPDSEGVQAEKEKEAAQCLEFLLQSGAAAALKDKQGYSPVHYAAAFGHRHCLELLLD---THDGRQEEADCGNAQSPLHLAAYHGHAQALQVLLRGGREVDERDQAGRTPLALAALRGHADCVHTLLSQGASPLSTDQLYGRTPVHLAVMNGHTTCVRLLLDEPDGAEVLDVADPQGRTPLMLAVVGGHVDAVSLL 684 HSP 2 Score: 193.356 bits (490), Expect = 9.742e-50 Identity = 177/597 (29.65%), Postives = 275/597 (46.06%), Query Frame = 2 Query: 1685 TISQ-LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAA---------LCLNSNSKYLDI---------IKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLE-NNADIDIVD----RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDN-FGCTPLHLASVEGQYECVNLLL--KSGAKPNEI-DNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQ--------------------------------------SQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLID-VGARI-DLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVA 3271 T SQ LI NG +IN V+++G T L VAA+ G + N L++SGA+ G L LA N + + + LLS D + GRT L AA G D V LLL SG N+ D GRTPL A Y ++ L+ G I+ D GRSA+ AA + L +S+ + ++ LL+ L D +G + + AA G + ++LL+ ++ + D +SPL AA+ G+ + +++LL G + D++G + L+++A +G++ + LL++G + D +G TP+HLA + G CV LLL GA+ ++ D GR PLML+ G++ L++ +VN G +L +A+L E V+ LL + A D+ GRTP+H++ Q Q C +VLL+ C+D + T +H A G L+D +G+ I +D +GRT LH A+ G + QLL+ +D G T L A+ +G + L++ GA + ID TP VA Sbjct: 320 TRSQTLIQNGGEINSVDKDGNTPLHVAARYGHELLINTLITSGADCARRGVHGMFPLHLAALNAHSDCCRKLLSSGFQIDTPDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYAAASRHYHCLETLVVCGTDINATDQWGRSALHYAAASDLDRRRRVALEPDSEGVQAEKEKEAAQCLEFLLQSGAAAALKDKQGYSPVHYAAAFGHRHCLELLLDTHDGRQEEADCGNAQSPLHLAAYHGHAQALQVLLRGGREVDERDQAGRTPLALAALRGHADCVHTLLSQGASPLSTDQLYGRTPVHLAVMNGHTTCVRLLLDEPDGAEVLDVADPQGRTPLMLAVVGGHVDAVSLLLE-REANVNTADKKGLMALHLALLCAQDECVQCLLEQDACLLQGDSQGRTPIHLAAAQGHASWLSELLTIACSESSSVPPLKDGSGYTPLHWACFYGQDGCVEVLLEQ------RGCRCIDGNPFTPLHCAVVNGHESCAALLLDAMGSDITGCRDAKGRTPLHAAAFAGQTECIQLLLSHDAPVDPADDHGRTPLMTAAAKGRVGALEALLDAGAGLSLIDRDGNTPLHVA 909 HSP 3 Score: 184.111 bits (466), Expect = 6.785e-47 Identity = 144/483 (29.81%), Postives = 230/483 (47.62%), Query Frame = 2 Query: 1847 ALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNH 3286 AL AI++G E +++L+ + D + + RT L AA++G +I LL+ SG+ +N +D+ TPL A V++L+ + A ++ +D + ++ + VAA N+ + ++I LL ++N+ D G L AA G + +LL A+I+ D+ A AAF G+ +VV +L+ GA + C DK G++ L +AS G ++ LL+ ++ + FG T LHLA GQ V+ L+ GA ++ +N G PL + S G+ L EFL++ GAD IQ +G++PLH++ + ++ Q L+Q N IN +D DG T +H+A+ G +I +LI GA + G LHL A C+ L+ G ID S G T L A+ G+++ LL+ G D C RTP A H Sbjct: 11 ALIQAIFSGDPEEIRMLIYKSEDINVLDAEKRTPLHAAAFLGDAEITELLILSGARVNAKDNMWFTPLHRAVASRSQDAVQVLIRHSADVNARDKNWQTPLHVAA--ANNALRCAEVIIPLL---TSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAA---------------------ASTHGALCL------------EFLVNNGADINIQSRDGKSPLHMTAVHGRFTRSQTLIQ-----NGGEINSVDKDGNTPLHVAARYGHELLINTLITSGADCARRGVHGMFPLHLAALNAHSDCCRKLLSSGFQIDTPDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYAAASRH 450 HSP 4 Score: 133.65 bits (335), Expect = 3.998e-31 Identity = 136/446 (30.49%), Postives = 194/446 (43.50%), Query Frame = 2 Query: 1736 NGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGN-DGRTALRTAAWIGRTDIVLLLL--SSGSNI-NKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEG-----SKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELL-ARGLDEMH-RDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIA-----------VLNRLPEF-------------------------VEFLLSRGADATIQDNNGRTP-LHISVLQSQYDCFQVLLQHSLTHN 2920 N + L +AA +G +LL G D+ G + L LA G+ + V LLSQ P T GRT + A G T V LLL G+ + + D +GRTPLM A V LLL A ++ D G A+ +A LC + ++ LL + + D++G + +AA +G S+LL E+++ + D S PL A F G V +LL CID + F+ L + G+ + LL A G D RD G TPLH A+ GQ EC+ LLL A + D+HGR PLM + +G + E L+D ++ DG+T L +A +L RL + V+ LLSRGA D +G TP L + + DC L HS +H+ Sbjct: 561 NAQSPLHLAAYHGHAQALQVLLRGGREVDERDQAGRTPLALAALRGHADCVHTLLSQGASPLSTDQLYGRTPVHLAVMNGHTTCVRLLLDEPDGAEVLDVADPQGRTPLMLAVVGGHVDAVSLLLEREANVNTADKKGLMALHLALLCAQD-----ECVQCLLEQDACLLQGDSQGRTPIHLAAAQGHASWLSELLTIACSESSSVPPLKDGSGYTPLHWACFYGQDGCVEVLLEQ-RGCRCIDGNPFTPLHCAVVNGHESCAALLLDAMGSDITGCRDAKGRTPLHAAAFAGQTECIQLLLSHDAPVDPADDHGRTPLMTAAAKGRVGALEALLDAG-AGLSLIDRDGNTPLHVACSNGTEDGVLMILQRLSDATLINATNAAMQTPLHMAAQRGLKKAVQELLSRGASTQTVDEDGLTPALACAPSRQVADC----LAHSGSHD 995 HSP 5 Score: 129.028 bits (323), Expect = 1.001e-29 Identity = 88/302 (29.14%), Postives = 145/302 (48.01%), Query Frame = 2 Query: 2327 IDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEIC-NLLINFGANV 3229 + + D+ L+ A FSG+ E +R+L++ I+ +D + L +A G+++I L+ G +DN TPLH A + V +L++ A N D + + PL ++ ++ AE +I + SVN G T+L A LN E V LL++GA+ D LH + D VL+ H ++C D G T +H A+ G ++K L+ + ID + G T LHL + G + LID+G N+ + ++G T L A+ H +C L+N GA++ Sbjct: 4 LKLADQPALIQAIFSGDPEEIRMLIYKSEDINVLDAEKRTPLHAAAFLGDAEITELLILSGARVNAKDNMWFTPLHRAVASRSQDAVQVLIRHSADVNARDKNWQTPLHVAAANNALRCAEVIIPLL-TSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGA-----EVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGADI 299 HSP 6 Score: 93.2041 bits (230), Expect = 9.652e-19 Identity = 104/375 (27.73%), Postives = 158/375 (42.13%), Query Frame = 2 Query: 1589 ILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLD----INCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGR----TDIVLLLLSSGSNINK-QDSEGRTPLM-AATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNIN-LIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDE--MHRDNFGC-TPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSC 2662 + + S ++ + +Y + N + T +L+++ D ++ + G T LM+A G +LLL AN DK G AL LA+ E V+ LL Q + GRT + AA G ++++ + S S++ +D G TPL A Y D + LL G DG F C N LL +I D +G L AA+ G ++LL ++A +D D R+PLM AA G + LL GA + ID+ G + L ++ S G + +L R D ++ N TPLH+A+ G + V LL GA +D G P L+C Sbjct: 611 VHTLLSQGASPLSTDQLYGRTPVHLAVMNGHTTCVRLLLDEPDGAEVLDVADPQGRTPLMLAVVGGHVDAVSLLLEREANVNTADKKGLMALHLALLCAQDECVQCLLEQDACLLQGDSQGRTPIHLAAAQGHASWLSELLTIACSESSSVPPLKDGSGYTPLHWACFYGQDGCVEVLLEQRGCRC----IDGNP--FTPLHCAVVNGHESCAALLLDAMGSDITGCRDAKGRTPLHAAAFAGQTECIQLLLSHDAPVDPADDHGRTPLMTAAAKGRVGALEALLDAGAGLSLIDRDGNTPLHVACSNGTEDGVLMILQRLSDATLINATNAAMQTPLHMAAQRGLKKAVQELLSRGASTQTVDEDGLTP-ALAC 978 HSP 7 Score: 81.6481 bits (200), Expect = 4.226e-15 Identity = 60/211 (28.44%), Postives = 94/211 (44.55%), Query Frame = 2 Query: 2711 ESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 E +N + T L A E E L+ GA +DN TPLH +V D QVL++HS ++N D + +T +H+A+ + +I + +++ D GRT LH A G ++ LL+ G NI+ + AL A+ GHL++ ++L++ GA V D TP A I + L +D N Sbjct: 32 EDINVLDAEKRTPLHAAAFLGDAEITELLILSGARVNAKDNMWFTPLHRAVASRSQDAVQVLIRHSA-----DVNARDKNWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNA 237 HSP 8 Score: 60.077 bits (144), Expect = 1.368e-8 Identity = 54/194 (27.84%), Postives = 86/194 (44.33%), Query Frame = 2 Query: 2909 LTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDN---------------------------------EGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSC-MRTPYKVAYKGNHIKICNLLEKHGALVDRKNV*LFYVIDIGFSSYYI 3388 L + +IN LD + RT +H A++ GD EI + LI GAR++ KDN +T LH+ A + +++I +++ + G TAL A+ GH E+ NLL+ GAN+ D R + A+ G H+ + ++L HGA V K+ + + SS I Sbjct: 27 LIYKSEDINVLDAEKRTPLHAAAFLGDAEITELLILSGARVNAKDNMWFTPLHRAVASRSQDAVQVLIRHSADVNARDKNWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMG-HLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQI 219
BLAST of Ankyrin repeat domain 50 vs. Planmine SMEST
Match: SMESG000028414.1 (SMESG000028414.1) HSP 1 Score: 2053.87 bits (5320), Expect = 0.000e+0 Identity = 1028/1052 (97.72%), Postives = 1029/1052 (97.81%), Query Frame = 2 Query: 188 KSTICRLLTTELTIDCFKTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 KSTICRLLTTELTIDCFKTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS MNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSG+SVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV Sbjct: 55 KSTICRLLTTELTIDCFKTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS-----------------------MNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGYSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 1083 HSP 2 Score: 86.2705 bits (212), Expect = 1.058e-16 Identity = 40/40 (100.00%), Postives = 40/40 (100.00%), Query Frame = 1 Query: 28 MINFIHGRSVNDSNLISKYLIQREWVFQKILHCINTRSCA 147 MINFIHGRSVNDSNLISKYLIQREWVFQKILHCINTRSCA Sbjct: 1 MINFIHGRSVNDSNLISKYLIQREWVFQKILHCINTRSCA 40
BLAST of Ankyrin repeat domain 50 vs. Planmine SMEST
Match: SMESG000028414.1 (SMESG000028414.1) HSP 1 Score: 2047.71 bits (5304), Expect = 0.000e+0 Identity = 1028/1055 (97.44%), Postives = 1029/1055 (97.54%), Query Frame = 2 Query: 188 KSTICRLLTTELTIDCFKTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 KSTICRLLTTELTIDCFKTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS MNMLLIAAYEGSKLLCKILLENNADIDIVDR SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSG+SVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV Sbjct: 55 KSTICRLLTTELTIDCFKTQKLKSLLLASHFCSASDIDSLNLAKFIFEIHQTLLKSKYFGEIYSRNINSSGLCNLFLSQNLCNYPDRAFKNGILLPLLSFPPPNENMYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFFPEWLSLVCTCRKENEFIVRKFMGFRKFYLDDLNKSYVIRDIQLYILNRIDKDDNLKQMINSETTELLNLLHIKSNGYIIYLEIVLDGILDGYLSIQVIKHIPGILCGLYLWIFETLFKHYQDFIVVKNIFNIMLSSLKSLSDQEIYCALLNLDINTDLYYLKDMLFKIKYFLVKTCDNCYHFRHNSLPEWLLDVKLCTPKYKCSLIDGHVNLALYNAYISSKLAPLQIRNFAFHLIASAPIFKFKGYHFAVWLLYSDCDIEVKGILPCEKFGSLNDWSIDDIVKILFESINLVNINKLNAKKSFTIFSTYILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS-----------------------MNMLLIAAYEGSKLLCKILLENNADIDIVDRNFRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGYSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 1086 HSP 2 Score: 86.2705 bits (212), Expect = 1.096e-16 Identity = 40/40 (100.00%), Postives = 40/40 (100.00%), Query Frame = 1 Query: 28 MINFIHGRSVNDSNLISKYLIQREWVFQKILHCINTRSCA 147 MINFIHGRSVNDSNLISKYLIQREWVFQKILHCINTRSCA Sbjct: 1 MINFIHGRSVNDSNLISKYLIQREWVFQKILHCINTRSCA 40
BLAST of Ankyrin repeat domain 50 vs. Planmine SMEST
Match: SMESG000028414.1 (SMESG000028414.1) HSP 1 Score: 935.636 bits (2417), Expect = 0.000e+0 Identity = 463/490 (94.49%), Postives = 464/490 (94.69%), Query Frame = 2 Query: 1883 VVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 VVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS MNMLLIAAYEGSKLLCKILLENNADIDIVDR SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSG+SVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV Sbjct: 66 VVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS-----------------------MNMLLIAAYEGSKLLCKILLENNADIDIVDRNFRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGYSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 532 HSP 2 Score: 117.087 bits (292), Expect = 6.963e-27 Identity = 102/339 (30.09%), Postives = 172/339 (50.74%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV--KLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLE-----NNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKI 2683 L+ N DI+ V+ N + LM AA +G + LLL GA IDK G+S L ++ G +++ LL++ +D N G T L A+ G+ + V LLL SG+ N+ D+ GR PLM + + Y+ + KL+ ++ + DG +++ +A L ++ + ++ LL + + DN G L I+ + ++LL+ N +I+ +D R+ + A++ G+ E+++ L+ GA I D G + L + A QG QI L+ G++ + G T L +AS EG E NLL+ GA ID+ R P ++ + +IKI Sbjct: 184 LLENNADIDIVDRNFRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGYSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQE-GYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVL-----NRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKI 516 HSP 3 Score: 112.849 bits (281), Expect = 1.746e-25 Identity = 107/395 (27.09%), Postives = 184/395 (46.58%), Query Frame = 2 Query: 1589 ILNITSTYSNSIEATNVYSFSLFESIRQNSYNTISQLIINGLDINCVNENGTTS---------------LMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDII-KLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAA-----IHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLID 2701 +L + S+ SN + + L + + Y + L+ NG I+ + +G ++ L++AA G +C +LL + A+ ++D++ S L A ++G EVV+LLL G + L +A G + I+ LL+ G + +D+ G TPL A+ + Y V LLL +GA + DN GR L L+ Y+ I KL+ + ++N +G L IA + LL AD I D R+PL + ++ ++LL I+C+D G + + I++ +G+ +I+ L+ G +DN G T LHL + +G Y+ LL+ G +E + G L ++ QEG+++I LI+ Sbjct: 100 VLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSMNMLLIAAYEGSKLLCKILLENNADIDIVDRNFRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGYSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGR-----IPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLIN 489 HSP 4 Score: 104.375 bits (259), Expect = 9.498e-23 Identity = 86/266 (32.33%), Postives = 137/266 (51.50%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDP-DFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPL----MAATYKCDYVMVK-LLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIV---DRSPLMAAAFSGNFEVVRLLLFWGAAIHCID 2431 S Q + +S+L+ GLD + G T L +A+ G NLLL SGA ID G L L+ GYI++ + L+ + +F DG T+L+ A + V LLS G++ QD+ GRTPL + + Y C V+++ L +N I+ D+DGR+AI +A+ + +IIK L+ I+L DNEG L + A++G +C++L++ +ID + L A+ G+ E+ LL+ +GA + ID Sbjct: 238 SASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDG-----EIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHID 498 HSP 5 Score: 73.9442 bits (180), Expect = 3.946e-13 Identity = 51/162 (31.48%), Postives = 89/162 (54.94%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGL-----DINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV-KLLLNNGAYIDHQD 2128 S+ Q+ Y+ L+ + L +INC++++G T++ +A+ G I L+ GA + D +G + L L W G ++ +LL+ I+ D T + G TAL A+ G +I LL++ G+N+ DS RTP A YK +++ + LL +GA +D ++ Sbjct: 371 SVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVA-YKGNHIKICNLLEKHGALVDRKN 531
BLAST of Ankyrin repeat domain 50 vs. Planmine SMEST
Match: SMESG000028414.1 (SMESG000028414.1) HSP 1 Score: 934.095 bits (2413), Expect = 0.000e+0 Identity = 463/491 (94.30%), Postives = 465/491 (94.70%), Query Frame = 2 Query: 1880 EVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 3343 +VVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS MNMLLIAAYEGSKLLCKILLENNADIDIVDR SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSG+SVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV Sbjct: 71 KVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNS-----------------------MNMLLIAAYEGSKLLCKILLENNADIDIVDRNFRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGYSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRKNV 538 HSP 2 Score: 117.087 bits (292), Expect = 7.274e-27 Identity = 102/339 (30.09%), Postives = 172/339 (50.74%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV--KLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLE-----NNADIDIVD---RSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKI 2683 L+ N DI+ V+ N + LM AA +G + LLL GA IDK G+S L ++ G +++ LL++ +D N G T L A+ G+ + V LLL SG+ N+ D+ GR PLM + + Y+ + KL+ ++ + DG +++ +A L ++ + ++ LL + + DN G L I+ + ++LL+ N +I+ +D R+ + A++ G+ E+++ L+ GA I D G + L + A QG QI L+ G++ + G T L +AS EG E NLL+ GA ID+ R P ++ + +IKI Sbjct: 190 LLENNADIDIVDRNFRSPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGYSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQE-GYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVL-----NRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKI 522 HSP 3 Score: 73.9442 bits (180), Expect = 4.183e-13 Identity = 51/162 (31.48%), Postives = 89/162 (54.94%), Query Frame = 2 Query: 1661 SIRQNSYNTISQLIINGL-----DINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMV-KLLLNNGAYIDHQD 2128 S+ Q+ Y+ L+ + L +INC++++G T++ +A+ G I L+ GA + D +G + L L W G ++ +LL+ I+ D T + G TAL A+ G +I LL++ G+N+ DS RTP A YK +++ + LL +GA +D ++ Sbjct: 377 SVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVA-YKGNHIKICNLLEKHGALVDRKN 537
BLAST of Ankyrin repeat domain 50 vs. Planmine SMEST
Match: SMESG000026655.1 (SMESG000026655.1) HSP 1 Score: 213.772 bits (543), Expect = 6.898e-56 Identity = 161/544 (29.60%), Postives = 272/544 (50.00%), Query Frame = 2 Query: 1697 LIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKI-LLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECV-NLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEK 3313 LI ++N V +G + + AA++GF +I +LL +GA+ K+G +AL++A EV + L+++ ID D D TAL AA G + +LL + N+N + G TPL A K MV+LL+ A+I+ G + + +AA SK +I+ +LL+ +I+ + N L +AA + KI LL A+ + R +PL A GN+ +V LL GA + + K ++ L I+A +G +I LL + G TPLH+AS G+ + LLL + PN + +HG PL ++ + ++ E L+D +VN +G T L + + E + L+ RGA+ Q G TPLH++ + + ++LL + ++N ++G TA+H+A+ K +I++ L+ A I K G T LH G Q ++L++ +++ + G T+L +A+Q+GH+ I LL++ +V H + T +VA K +++ I L K Sbjct: 259 LISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFM---GSK--EIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEA-NVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANA-----DVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLEKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSK 791 HSP 2 Score: 187.193 bits (474), Expect = 1.562e-47 Identity = 154/589 (26.15%), Postives = 270/589 (45.84%), Query Frame = 2 Query: 1643 SFSLFESIRQNSYNTISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAY------------------------------IDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDR---SPLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEIC-NLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLL 3307 + + + R + + + + + + N NG ++ +AA+ G + LL+ +G + + + G ++L +A G +EVV LLL K + + +G T L AA D+V +LL G+N +G TPL A + + +V++LL+N + +DHQ G + + +AA N N + KLL+ N ++N + L +AA G + + K+L+ A+++ V R SP+ AA SG ++ +LL GA I K+G + L ++ +++ L+ +G+D T LH+A+ G +LLK+ N +G PL ++C++ K+ E LI + +N + G T L IA E V LL GA + LH++ +Q + F++LL H N N + +T +HIA G+ I++ L++ GA ++ + T LH+ A +G ++I +LL++ D +G T L IAS+ G +++ LL++ N + TP VA NH ++ LL Sbjct: 13 AHAFLRAARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVN-----VAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIK-YKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEA----NFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELL 591 HSP 3 Score: 177.563 bits (449), Expect = 1.243e-44 Identity = 163/559 (29.16%), Postives = 262/559 (46.87%), Query Frame = 2 Query: 1688 ISQLIINGLDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAW--IGRTDIV----LLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPE-FVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQIC-QLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVD 3331 +S L+ + +IN ++NG T L +AAQ + +LL GANQ + DG++ L +A+ G +VV++LL ND R+ +R A + D V LL+ SS N++ Q + G TPL A + + + KLL+ A ++ + + + VAA +++KLL+ N+N + +G++ + AA G + + ILLEN ADI ++ L A A EV + L+ G + + + L ++A GN LL + R G TPLH+A + Q + V LL+K A N G PL ++ G +I L+ S++ + +L +A N E F LL A+ + +TPLHI+V Y + LL + N + D TA+HIA+ +G EI + L++ + D K +G T LH+ + G Q+ QLL+ +N + G T L +A+ H E+ LL++ ANV + TP + K N I++ LL GA V+ Sbjct: 94 VSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILLD---------NDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKE-----EMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGA-SISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGA-----DPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVN 632 HSP 4 Score: 172.17 bits (435), Expect = 6.129e-43 Identity = 163/570 (28.60%), Postives = 257/570 (45.09%), Query Frame = 2 Query: 1649 SLFESIRQNSYNTISQLIINGLD-INCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVLLLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRS---PLMAAAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELL---ARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDVWPESVNFKSYDGSTSLKIAVLNRLPEFVEFLLSRGADATIQDNNGRTPLHISVLQSQYDCFQVLLQHSLTHNINNINCLDDDGRTAIHIASWKGDGEIIKSLIDVGARIDLKDNEGRTGLHLGAWQGCYQICQLLIDFGINIDETCSQGATALSIASQEGHLEICNLLINFGANVCHIDSCMRTPYKVAYKGNHIKICNLLEKHGALVDRK 3337 +L + +++ N S LI + D ++ + +G T L +AA ++ LL+ A+ K+ + L +A G E++KLL+SQK + + DG + + AA G +I+L+LL +G++I + G T L AT + + L+N G +D D +A+ VAA C N N+ ++LL+ NCN+N G L IA + + ++L++ A I+ + PL AAF G+ E+V +LL GA+I + L ++A + LL + R+N TPLH+A G Y V LL +GA P N + D T+L IA E LL + G TPLHI+ S+Y QV Q L+ +N N L G T +H+A++ E+I+ L+D A ++ G T LHL A + ++ +LLID G N++ +G T L + S G+ EI LL++ A+V H T +A + N I L K A + K Sbjct: 176 ALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAA-----EVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARAREN--QTPLHIAVRMGNYSIVEQLLNAGADP----------------------------------NMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIA---SKYGRVQVARQLLLSAKVNP-NSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTK 700 HSP 5 Score: 143.665 bits (361), Expect = 3.657e-34 Identity = 115/381 (30.18%), Postives = 181/381 (47.51%), Query Frame = 2 Query: 1580 STYILNITSTYSNSIEATNVY-SFSLFESIRQNSYNTISQLIING-LDINCVNENGTTSLMVAAQNGFTSICNLLLSSGANQLMIDKDGWSALRLAIWNGYIEVVKLLLSQKIDPDFTGNDGRTALRTAAWIGRTDIVL-LLLSSGSNINKQDSEGRTPLMAATYKCDYVMVKLLLNNGAYIDHQDNDGRSAIFVAALCLNSNSKYLDIIKLLLRYNCNINLIDNEGMNMLLIAAYEGSKLLCKILLENNADIDIVDRSPLMA---AAFSGNFEVVRLLLFWGAAIHCIDKSGFSVLSISASQGNSQILSELLARGLDEMHRDNFGCTPLHLASVEGQYECVNLLLKSGAKPNEIDNHGRIPLMLSCQEGYIKIAEKLIDV 2704 S I+NI SI T + +L + R N T L+++ + N T L +A + G SI LL++GA+ M+ KD ++AL +A G E+ +LLL + PD G T L A+ GR + LLLS+ N N G TPL ATY Y M++LLL+ A ++ +G + + + A +++ KLL+ N+N +G L + + G+K + ++LL+ NAD++ + L A AA ++V LL A I + G++ L + G Q + LL + D + N GCT LHLA+ +G V LLL + N + G L ++ ++ Y+ IAE L V Sbjct: 417 SKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVA-----KKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLEKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSKV 792 The following BLAST results are available for this feature:
BLAST of Ankyrin repeat domain 50 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Ankyrin repeat domain 50 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30005209 ID=SMED30005209|Name=Ankyrin repeat domain 50|organism=Schmidtea mediterranea sexual|type=transcript|length=3629bpback to top protein sequence of SMED30005209-orf-1 >SMED30005209-orf-1 ID=SMED30005209-orf-1|Name=SMED30005209-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=947bp MYILIDSIDENLLSDYLGEKLSYIFNKDTFHKNRQGSKNISDLLSAHHNFback to top Annotated Terms
The following terms have been associated with this transcript:
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