SAM-dependent MTase TRM10-type domain-containing protein

Overview
NameSAM-dependent MTase TRM10-type domain-containing protein
Smed IDSMED30005144
Length (bp)2356
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SAM-dependent MTase TRM10-type domain-containing protein (SMED30005144) t-SNE clustered cells

Violin plots show distribution of expression levels for SAM-dependent MTase TRM10-type domain-containing protein (SMED30005144) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SAM-dependent MTase TRM10-type domain-containing protein (SMED30005144) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SAM-dependent MTase TRM10-type domain-containing protein (SMED30005144) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30005144

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30005144SMESG000075125.1 SmedASXL_010653SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Human
Match: TRMT10C (tRNA methyltransferase 10C, mitochondrial RNase P subunit [Source:HGNC Symbol;Acc:HGNC:26022])

HSP 1 Score: 88.1965 bits (217), Expect = 7.061e-18
Identity = 67/265 (25.28%), Postives = 126/265 (47.55%), Query Frame = 2 
Query:  329 RKKYFSFLTKKQFSKENDLLKKSQKIP---KWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            +KKY  +L  K+  K+   +KK  K     + K +      E  + KN  F + + +   I +  +   A+    Q ++FD  +E+ M R++++    Q       N+   DPF +   +LK     + +L K +            +        EK  ++++P   +IYL+ DS     +  + HD +YV+G+ VD+  Q   +L+KA+   L    LPLD ++QW+ G + L L+   +I+ +  + +G+W++A+ Q +P R
Sbjct:  129 KKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETTEEDKQKNFLFLRLWDRNMDIAMGWKGAQAMQF-GQPLVFDMAYENYMKRKELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQ---------EKWDKLLLTSTEKSHVDLFPKDSIIYLTADSPN--VMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTLDQMIRIL-LCLKNNGNWQEAL-QFVPKR 379
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Human
Match: TRMT10A (tRNA methyltransferase 10A [Source:HGNC Symbol;Acc:HGNC:28403])

HSP 1 Score: 77.411 bits (189), Expect = 1.629e-14
Identity = 61/202 (30.20%), Postives = 100/202 (49.50%), Query Frame = 2 
Query:  509 KQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            ++R+   ++ ++ ++I D  F+  M  +D+K+L +Q Q CY+ N+    P Q  LTS   Q     D N     N      +++ H  P     + + E+   + LIYL+ DS   L+  E D    YV+G +VD +  K LT  +A   G+ H  LPL +FV+     + L +N  F+I+    ET  DW++A    +P R
Sbjct:   89 RKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVN------WKDIHIKP-----EHYSELIKKEDLIYLTSDSPNILK--ELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM-NSRKVLAVNHVFEIILEYLETR-DWQEAFFTILPQR 275
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Human
Match: TRMT10A (tRNA methyltransferase 10A [Source:HGNC Symbol;Acc:HGNC:28403])

HSP 1 Score: 77.411 bits (189), Expect = 1.629e-14
Identity = 61/202 (30.20%), Postives = 100/202 (49.50%), Query Frame = 2 
Query:  509 KQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            ++R+   ++ ++ ++I D  F+  M  +D+K+L +Q Q CY+ N+    P Q  LTS   Q     D N     N      +++ H  P     + + E+   + LIYL+ DS   L+  E D    YV+G +VD +  K LT  +A   G+ H  LPL +FV+     + L +N  F+I+    ET  DW++A    +P R
Sbjct:   89 RKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVN------WKDIHIKP-----EHYSELIKKEDLIYLTSDSPNILK--ELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM-NSRKVLAVNHVFEIILEYLETR-DWQEAFFTILPQR 275
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Human
Match: TRMT10A (tRNA methyltransferase 10A [Source:HGNC Symbol;Acc:HGNC:28403])

HSP 1 Score: 77.411 bits (189), Expect = 1.629e-14
Identity = 61/202 (30.20%), Postives = 100/202 (49.50%), Query Frame = 2 
Query:  509 KQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            ++R+   ++ ++ ++I D  F+  M  +D+K+L +Q Q CY+ N+    P Q  LTS   Q     D N     N      +++ H  P     + + E+   + LIYL+ DS   L+  E D    YV+G +VD +  K LT  +A   G+ H  LPL +FV+     + L +N  F+I+    ET  DW++A    +P R
Sbjct:   89 RKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVN------WKDIHIKP-----EHYSELIKKEDLIYLTSDSPNILK--ELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKM-NSRKVLAVNHVFEIILEYLETR-DWQEAFFTILPQR 275
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Human
Match: TRMT10B (tRNA methyltransferase 10B [Source:HGNC Symbol;Acc:HGNC:26454])

HSP 1 Score: 70.8626 bits (172), Expect = 3.964e-13
Identity = 49/193 (25.39%), Postives = 92/193 (47.67%), Query Frame = 2 
Query:  548 QIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSIPS 1111
            ++  D      M+++++  L+ Q +  Y  NK    PF + LT     S  Y +  +   G          F  +   I E+    ++P + L+YL+PDS+  L+  + D + +Y++G +VD   QK +T  KAR   ++   LP+ +++   Q  +      L +N  F I+S   ET  +W +A+++ + S
Sbjct:   31 RLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECVRMNDG----------FSSYLLDITEEDCFSLFPLETLVYLTPDSEHALE--DVDLNKVYILGGLVDESIQKKVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETH-NWPEALKKGVSS 210
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Celegans
Match: F46F11.10 (pep chromosome:WBcel235:I:5623019:5624475:-1 gene:WBGene00018513.1 transcript:F46F11.10.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F46F11.10)

HSP 1 Score: 83.9593 bits (206), Expect = 6.027e-17
Identity = 94/327 (28.75%), Postives = 159/327 (48.62%), Query Frame = 2 
Query:  170 PATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXXXXXXXXXNYFQRKKYFS---FLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQII-FDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPD--KKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQ----KPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETS--GDWKKAIQQSIPSR 1114
            P++E   +L+EE+  R++ I  E   +  L    P  + D +    L L    RK  F    FL +K+  +E D  KK +K+   KI   E  V  +++ +          E+ Y  +RL+ A +L ++ I+  D  F   ++ R     + Q Q   + N+   DPF++   +   ++ +  DL K  + ++ K+      H F  ++ E   +E Y +  K +IYLSPD+  +L+    D D IYV+G IVDR  +    K  +L  ++  G+  R LP+D +V +K G + L L     +  I R+ +  GDWKKA++ +IP R
Sbjct:   42 PSSEFRENLSEEENKRIDRILEELFLFSRLSVRFPKKISDSEWKTFLELK--SRKSRFDEAMFLFRKEKLEEEDARKKLEKVNFRKI--SEQNV-GSRVPSYMLHFPNSVSEEYYQMKRLYEAYLLENRPILAVDCQFLSRLSPRGRGLTALQLQYLITENRRNPDPFRLHFVNYDSKNSSIQDLEKSKLQSIRKS------HVFNPIVTENG-LETYENHSKNVIYLSPDATEELE--SVDDDKIYVIGGIVDRVPEPGIPKHASLEASQSAGVFARKLPIDRYVDFKSGSKFLTL---LAVAEILRQVNIHGDWKKAMKVAIPVR 351
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Celegans
Match: F25H8.1 (pep chromosome:WBcel235:IV:9930899:9932240:-1 gene:WBGene00009131.1 transcript:F25H8.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F25H8.1)

HSP 1 Score: 76.2554 bits (186), Expect = 7.874e-15
Identity = 52/190 (27.37%), Postives = 92/190 (48.42%), Query Frame = 2 
Query:  545 QQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            Q+I  D  F+D M  +D K   +Q   CY+ N+   DPFQ  +      S    D N++ +         ++ H     ++++    ++  ++++YL+ +S+    L + D   +YV+G IVD + QK L    A+ +G  H  LPLD+ +  K   R L +N  ++I+ +      +WK A+   IP R
Sbjct:   87 QRIALDMSFDDLMIEKDQKRTVQQIGWCYTANRHSPDPFQFHVVGFDGPSRKIYDGNEHNLN--------QDIH-----LHQEKLENLFKPEEIVYLTSESEN--VLSDLDDTKVYVIGGIVDHNSQKGLCYRIAQEKGFGHAKLPLDEHLLMK-SRRVLTINQVYEIL-VHYSVHKNWKDALLSIIPER 259
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Celegans
Match: F25H8.1 (pep chromosome:WBcel235:IV:9930899:9932213:-1 gene:WBGene00009131.1 transcript:F25H8.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F25H8.1)

HSP 1 Score: 76.2554 bits (186), Expect = 8.447e-15
Identity = 52/190 (27.37%), Postives = 92/190 (48.42%), Query Frame = 2 
Query:  545 QQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            Q+I  D  F+D M  +D K   +Q   CY+ N+   DPFQ  +      S    D N++ +         ++ H     ++++    ++  ++++YL+ +S+    L + D   +YV+G IVD + QK L    A+ +G  H  LPLD+ +  K   R L +N  ++I+ +      +WK A+   IP R
Sbjct:   86 QRIALDMSFDDLMIEKDQKRTVQQIGWCYTANRHSPDPFQFHVVGFDGPSRKIYDGNEHNLN--------QDIH-----LHQEKLENLFKPEEIVYLTSESEN--VLSDLDDTKVYVIGGIVDHNSQKGLCYRIAQEKGFGHAKLPLDEHLLMK-SRRVLTINQVYEIL-VHYSVHKNWKDALLSIIPER 258
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Celegans
Match: C56G2.3 (pep chromosome:WBcel235:III:6346285:6348121:1 gene:WBGene00016978.1 transcript:C56G2.3.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C56G2.3)

HSP 1 Score: 67.3958 bits (163), Expect = 1.436e-11
Identity = 59/211 (27.96%), Postives = 94/211 (44.55%), Query Frame = 2 
Query:  515 RLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNK---YFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYP-DKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARET---SGDWKKAIQQSIPSRMIFN 1126
            ++F+A+   + +I  D  + ++M +RD  EL  Q Q   S N S + PF +   +   +      L+K   Y+ GN +      +F         K   E Y      IY+S +++  L  G    D   V+G  V   G+K   LS AR   +    LP+  +V+WK G + LP      IM++ RE     GDW +A+  +I  R + N
Sbjct:  176 KIFAAMNSGAPRIALDIQYVEEMNKRDSGELGNQMQYTISENFSAKSPFVLDFVNSPSKEFLEQWLSKSVGYYTGNYINQTILPDFST-------KGIKEFYGKSANTIYISSNARDVLD-GPLTAD---VIGICVTM-GRKREALSAARRANIRAYRLPIHRYVKWKSGPQYLPFP---NIMNVLREVYMNGGDWSRALHNNISKRHLVN 371
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Celegans
Match: C56G2.3 (pep chromosome:WBcel235:III:6346285:6348121:1 gene:WBGene00016978.1 transcript:C56G2.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C56G2.3)

HSP 1 Score: 67.3958 bits (163), Expect = 1.436e-11
Identity = 59/211 (27.96%), Postives = 94/211 (44.55%), Query Frame = 2 
Query:  515 RLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNK---YFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYP-DKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARET---SGDWKKAIQQSIPSRMIFN 1126
            ++F+A+   + +I  D  + ++M +RD  EL  Q Q   S N S + PF +   +   +      L+K   Y+ GN +      +F         K   E Y      IY+S +++  L  G    D   V+G  V   G+K   LS AR   +    LP+  +V+WK G + LP      IM++ RE     GDW +A+  +I  R + N
Sbjct:  176 KIFAAMNSGAPRIALDIQYVEEMNKRDSGELGNQMQYTISENFSAKSPFVLDFVNSPSKEFLEQWLSKSVGYYTGNYINQTILPDFST-------KGIKEFYGKSANTIYISSNARDVLD-GPLTAD---VIGICVTM-GRKREALSAARRANIRAYRLPIHRYVKWKSGPQYLPFP---NIMNVLREVYMNGGDWSRALHNNISKRHLVN 371
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Fly
Match: rswl (gene:FBgn0034351 transcript:FBtr0086696)

HSP 1 Score: 105.531 bits (262), Expect = 1.074e-23
Identity = 76/279 (27.24%), Postives = 135/279 (48.39%), Query Frame = 2 
Query:  329 RKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFG--------KYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYF--MGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGY-RGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 1132
            R KYF +L + +  KE D  KK+++  + +    E   E  +  +  +G        + Y      +   RL  A+   + +++ D  +++ M  R+    ++Q   C++ N+   +PF +   + +  S     L +Y   M N           +FP  ++ K F E++P + L+YL+P  +  L    Y+ D IY+VGA+VD    +PL+L+KA+  GL    LPLD ++QW  G  + L LN    IM   ++T GDW  A++     +++ N+F
Sbjct:  112 RIKYFGYLWQIEMKKEADQRKKAERAKEAERRVAEMRKEREENTHIIYGLGHTSLFLRIYDTTINHWQNNRLTRAMQF-APKMVLDCSYDEHMNNREATYAAKQLMMCFAENRMNDEPFDLHYCNTQMDSRCMQSLQRYIPTMHNP----------EFPINLHSKCFTELFPKQNLVYLTPHCREDLVT--YNPDDIYIVGAMVDTMNNEPLSLAKAKRLGLRMARLPLDRYLQWGSGSGKSLTLNQMINIMLDLKKT-GDWDTALKHVPRRKVVQNEF 376
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Fly
Match: CG14618 (gene:FBgn0031189 transcript:FBtr0077351)

HSP 1 Score: 57.3806 bits (137), Expect = 2.046e-8
Identity = 51/206 (24.76%), Postives = 91/206 (44.17%), Query Frame = 2 
Query:  506 LKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKM---KLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            LK+R  +    +   +  D  ++D M  RD+ +  +Q    Y+IN+    P  +  T ++         N +   +  K   + N+H   +  +++   +++   +L+YL+ +S     KLQ G       YV+G +VD +  K L  S+A   GL    LPL + V  K     L     F++++       DW  AI ++IP R
Sbjct:   82 LKKRQLADGGKSGLSVAIDLDYDDLMQERDIVKCVKQCLRIYTINRRSPQPGNLHFTGIRR--------NGHIHESFKKNEGWENWHVQYY--FDRGHTDIFEHSQLVYLTCESDRVLDKLQPG-----CTYVIGGLVDHNHFKGLCHSRATSAGLTTARLPLSEHVDMKT-RAVLSTYHVFELLTKV-AAGQDWTTAILETIPMR 270
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Zebrafish
Match: trmt10c (tRNA methyltransferase 10C, mitochondrial RNase P subunit [Source:ZFIN;Acc:ZDB-GENE-041114-12])

HSP 1 Score: 88.1965 bits (217), Expect = 5.433e-18
Identity = 69/280 (24.64%), Postives = 130/280 (46.43%), Query Frame = 2 
Query:  329 RKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNN----------------FFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDL--NKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            +KKY  FL  K+  K ND  K+ +K          +E EA +++NN                F  +      +     R   A+  + Q ++FD  ++  M+R +++    Q       N+ +++PF           L +C+L     +   +L+      +        E+  +E++P + L+YL+ DS+  L+   +DH  +Y+VGA+VDR  +   +L+ A+   L    LPLD+++ W  G + L L+   +I++  ++T G W+KA+ + +P R
Sbjct:  111 KKKYLKFLAIKEAQKNNDKRKQEKK---------RAEREAGKLQNNNGEEEEEERAAGPENTFMLRLRNNSIESAHNWRTAQAMRFD-QPLVFDMSYDQQMSRHELENTVSQLLESEGFNRRVQEPFH----------LHFCNLQPGGAYHRELLRRYGDETWRRLLITHTERSPLELFPHQDLVYLTADSRSVLRT--FDHTKVYIVGAMVDRSIRVGASLAIAKRFRLATARLPLDEYLDWDCGAKNLTLDQMIRILTTVKQT-GCWQKAL-EFVPKR 366
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Zebrafish
Match: trmt10b (tRNA methyltransferase 10B [Source:NCBI gene;Acc:768135])

HSP 1 Score: 84.7297 bits (208), Expect = 2.269e-17
Identity = 57/209 (27.27%), Postives = 101/209 (48.33%), Query Frame = 2 
Query:  497 KIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSIP 1108
            K   K+RL  A      ++  D    + +T +++  L+ Q +  Y  NK    PF + LT L+  SL Y +  +   G          F  +   + E+ +  ++P + +IYL+PD+   L+    + D IY++G +VD   QK ++ +KA+  G+    LP+D+++  K+  +      L +N  F I+   R+T  DW KA+   IP
Sbjct:   98 KAITKERLEEA-RAAGLRLCVDLSMTEHLTHKEISRLAAQIRRLYGSNKKALQPFHVFLTELQEDSLLYKECVRMNDG----------FMHYLIDVTEESWFHLFPSEDVIYLTPDASEALE--SVEEDKIYILGGLVDETIQKKISYTKAKELGVRTARLPIDEYMVKKKNPKNFHSKILAINQVFDILLTFRDTR-DWTKALMAGIP 292
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Zebrafish
Match: trmt10b (tRNA methyltransferase 10B [Source:NCBI gene;Acc:768135])

HSP 1 Score: 84.7297 bits (208), Expect = 2.269e-17
Identity = 57/209 (27.27%), Postives = 101/209 (48.33%), Query Frame = 2 
Query:  497 KIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSIP 1108
            K   K+RL  A      ++  D    + +T +++  L+ Q +  Y  NK    PF + LT L+  SL Y +  +   G          F  +   + E+ +  ++P + +IYL+PD+   L+    + D IY++G +VD   QK ++ +KA+  G+    LP+D+++  K+  +      L +N  F I+   R+T  DW KA+   IP
Sbjct:   98 KAITKERLEEA-RAAGLRLCVDLSMTEHLTHKEISRLAAQIRRLYGSNKKALQPFHVFLTELQEDSLLYKECVRMNDG----------FMHYLIDVTEESWFHLFPSEDVIYLTPDASEALE--SVEEDKIYILGGLVDETIQKKISYTKAKELGVRTARLPIDEYMVKKKNPKNFHSKILAINQVFDILLTFRDTR-DWTKALMAGIP 292
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Zebrafish
Match: trmt10b (tRNA methyltransferase 10B [Source:NCBI gene;Acc:768135])

HSP 1 Score: 84.7297 bits (208), Expect = 2.269e-17
Identity = 57/209 (27.27%), Postives = 101/209 (48.33%), Query Frame = 2 
Query:  497 KIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSIP 1108
            K   K+RL  A      ++  D    + +T +++  L+ Q +  Y  NK    PF + LT L+  SL Y +  +   G          F  +   + E+ +  ++P + +IYL+PD+   L+    + D IY++G +VD   QK ++ +KA+  G+    LP+D+++  K+  +      L +N  F I+   R+T  DW KA+   IP
Sbjct:   98 KAITKERLEEA-RAAGLRLCVDLSMTEHLTHKEISRLAAQIRRLYGSNKKALQPFHVFLTELQEDSLLYKECVRMNDG----------FMHYLIDVTEESWFHLFPSEDVIYLTPDASEALE--SVEEDKIYILGGLVDETIQKKISYTKAKELGVRTARLPIDEYMVKKKNPKNFHSKILAINQVFDILLTFRDTR-DWTKALMAGIP 292
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Zebrafish
Match: trmt10c (tRNA methyltransferase 10C, mitochondrial RNase P subunit [Source:ZFIN;Acc:ZDB-GENE-041114-12])

HSP 1 Score: 82.0333 bits (201), Expect = 1.585e-16
Identity = 50/192 (26.04%), Postives = 99/192 (51.56%), Query Frame = 2 
Query:  545 QQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDL--NKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            Q ++FD  ++  M+R +++    Q       N+ +++PF           L +C+L     +   +L+      +        E+  +E++P + L+YL+ DS+  L+   +DH  +Y+VGA+VDR  +   +L+ A+   L    LPLD+++ W  G + L L+   +I++  ++T G W+KA+ + +P R
Sbjct:   78 QPLVFDMSYDQQMSRHELENTVSQLLESEGFNRRVQEPFH----------LHFCNLQPGGAYHRELLRRYGDETWRRLLITHTERSPLELFPHQDLVYLTADSRSVLRT--FDHTKVYIVGAMVDRSIRVGASLAIAKRFRLATARLPLDEYLDWDCGAKNLTLDQMIRILTTVKQT-GCWQKAL-EFVPKR 255
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Xenopus
Match: trmt10c (tRNA methyltransferase 10C, mitochondrial RNase P subunit [Source:NCBI gene;Acc:100124885])

HSP 1 Score: 102.449 bits (254), Expect = 2.306e-22
Identity = 76/267 (28.46%), Postives = 137/267 (51.31%), Query Frame = 2 
Query:  329 RKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNP----ESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIY-EKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            RKKY  +L+ ++  K N   KK +       +      E++ +  + KN F    + K      + +   A+    Q ++FD  +E +M+R +++    Q       N+   DPF +   SL+  S+ + +L K ++G      A+ N     FV   +K  +E++P ++L+YL+ DS  +L+   +DH  IY++G++VDR  Q  L+L+ A+   L    LPLD +++W  G + L L+   +I+   ++T GDWKKA+   +P+R
Sbjct:  127 RKKYLKYLSVREVMKTNRKEKKKELKESKSKIESLDQLETKEDTPEKKNTFLLHVWDKSIDTMQRWKCVQAMKF-GQPLVFDMVYEKNMSRYELENTVCQLMESEGWNRRSTDPFHIYFCSLQPYSMYHKELVKRYIG------AWDNV----FVTATDKSHVEMFPKEQLVYLTADSPNELK--HFDHTKIYIIGSLVDRCQQTGLSLANAKRLNLATARLPLDRYLKWDVGAKNLTLDQMIRILLCLKDT-GDWKKAL-SFVPNR 378
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Xenopus
Match: TRMT10B (tRNA methyltransferase 10B [Source:NCBI gene;Acc:100493764])

HSP 1 Score: 81.2629 bits (199), Expect = 1.976e-16
Identity = 65/244 (26.64%), Postives = 112/244 (45.90%), Query Frame = 2 
Query:  389 KKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSI 1105
            K+ Q+  + K  N E+  +A Q       K+  K  K   K+ L  A   +  ++  D      MT++++  LS Q +  Y  NK    PF + LTS    SL Y +  +   G          F ++     E  F++++P + ++YL+PDS   L+  + + + +YV+G +VD   QK LT  KAR  GL+   LP+ +++      +      L +N  F ++S    T   W +A+Q  +
Sbjct:    3 KRKQEKERRKAKNAENVEQAEQ-------KHSKKFLKALTKEHLLEAKN-SGPRLCIDLSMTQHMTKKELSRLSAQIRRLYGSNKKAAKPFWLYLTSFAGNSLFYDECVRMNDG----------FVNYLVDTTENSFLDIFPLETVVYLTPDSDNALE--DVNPEKVYVLGGLVDESIQKKLTYHKAREHGLQTARLPIQEYMVKNVNVKNFHSEILAINQVFDVLSTYCRTQS-WPEALQAGV 225
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Xenopus
Match: TRMT10B (tRNA methyltransferase 10B [Source:NCBI gene;Acc:100493764])

HSP 1 Score: 79.7221 bits (195), Expect = 3.508e-16
Identity = 53/194 (27.32%), Postives = 93/194 (47.94%), Query Frame = 2 
Query:  548 QIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCD---LNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSI 1105
            ++  D      MT++++  LS Q +  Y  NK    PF + LTS    SL Y +   +N  F+  ++ T              E  F++++P + ++YL+PDS   L+  + + + +YV+G +VD   QK LT  KAR  GL+   LP+ +++      +      L +N  F ++S    T   W +A+Q  +
Sbjct:   25 RLCIDLSMTQHMTKKELSRLSAQIRRLYGSNKKAAKPFWLYLTSFAGNSLFYDECVRMNDGFVNYLVDTT-------------ENSFLDIFPLETVVYLTPDSDNALE--DVNPEKVYVLGGLVDESIQKKLTYHKAREHGLQTARLPIQEYMVKNVNVKNFHSEILAINQVFDVLSTYCRTQS-WPEALQAGV 202
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Xenopus
Match: trmt10a (tRNA methyltransferase 10A [Source:NCBI gene;Acc:493374])

HSP 1 Score: 80.4925 bits (197), Expect = 1.190e-15
Identity = 61/204 (29.90%), Postives = 105/204 (51.47%), Query Frame = 2 
Query:  509 KQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKP--FIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            ++R    +  ++ ++I D  F+D M  RDVK+L++Q + CY+ N+    P Q+ LTS  H      ++++Y  G       + N+ D    I+ KP  + ++   + L+YL+ DS     L E D    Y++G +VD +  K +T  KA   G+ H  LPL +FV+     + L +N  F+I+ +A     +WK+A    +P R
Sbjct:   99 RKRFRHEVQPSALRLIIDCSFDDLMALRDVKKLNKQIRRCYAENRRAVHPVQLYLTS--HGGQLKSNMDEYDKG-------WINWKD----IHIKPEHYKDLIKKEDLVYLTSDSPEV--LSELDETKAYIIGGLVDHNHHKGITYKKALELGISHAQLPLGNFVKM-NTRKVLAVNHVFEII-LAFLEKKEWKEAFFSVLPQR 285
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Mouse
Match: Trmt10a (tRNA methyltransferase 10A [Source:MGI Symbol;Acc:MGI:1920421])

HSP 1 Score: 83.5741 bits (205), Expect = 9.099e-17
Identity = 62/202 (30.69%), Postives = 101/202 (50.00%), Query Frame = 2 
Query:  509 KQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            ++R+   +  +S +++ D  F+D M  +D+K+L +Q Q CY+ N+    P Q  LTS   Q     D N     N      +++ H     I  + + E+   + L+YL+ DS   L+  + D    YV+G +VD +  K LT  +A   G+EH  LPL DFV+     + L +N  F+I+    ET  DW++A    +P R
Sbjct:   90 RKRVRRDVARSSLRLVIDCSFDDLMVLKDIKKLHKQIQRCYAENRRASHPVQFYLTSHGGQLKKNMDENDQGWVN------WKDIH-----IKSEHYSELIKKEDLVYLTSDSPNVLK--DLDESKAYVIGGLVDHNHHKGLTFKQATSYGIEHAQLPLADFVKMN-SRKVLAVNHVFEIILEFLETR-DWQEAFFTILPQR 276
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Mouse
Match: Trmt10a (tRNA methyltransferase 10A [Source:MGI Symbol;Acc:MGI:1920421])

HSP 1 Score: 83.5741 bits (205), Expect = 9.099e-17
Identity = 62/202 (30.69%), Postives = 101/202 (50.00%), Query Frame = 2 
Query:  509 KQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            ++R+   +  +S +++ D  F+D M  +D+K+L +Q Q CY+ N+    P Q  LTS   Q     D N     N      +++ H     I  + + E+   + L+YL+ DS   L+  + D    YV+G +VD +  K LT  +A   G+EH  LPL DFV+     + L +N  F+I+    ET  DW++A    +P R
Sbjct:   90 RKRVRRDVARSSLRLVIDCSFDDLMVLKDIKKLHKQIQRCYAENRRASHPVQFYLTSHGGQLKKNMDENDQGWVN------WKDIH-----IKSEHYSELIKKEDLVYLTSDSPNVLK--DLDESKAYVIGGLVDHNHHKGLTFKQATSYGIEHAQLPLADFVKMN-SRKVLAVNHVFEIILEFLETR-DWQEAFFTILPQR 276
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Mouse
Match: Trmt10c (tRNA methyltransferase 10C, mitochondrial RNase P subunit [Source:MGI Symbol;Acc:MGI:1196261])

HSP 1 Score: 78.9518 bits (193), Expect = 6.473e-15
Identity = 49/191 (25.65%), Postives = 95/191 (49.74%), Query Frame = 2 
Query:  542 SQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
             Q ++FD  +++ M   +++    Q       N+   DPF +   +LK  S  + +L K +            +        EK  ++++P   +IYL+ DS   +    + HD IY++G+ VD++ Q   +L+KA+   +    LPLD ++QW+ G + L L+   +I+   + T G+W++A+ + +P R
Sbjct:  197 GQPLVFDMAYDNYMKPSELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDSAYHRELVKRYR---------EKWDKLLLTATEKSPVDLFPKDSIIYLTADSPNVMTT--FKHDKIYIIGSFVDKNTQTGTSLAKAKRLNIATECLPLDKYLQWEIGNKNLTLDQMIRILLCLKNT-GNWEEAL-KFVPRR 374
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Mouse
Match: Trmt10b (tRNA methyltransferase 10B [Source:MGI Symbol;Acc:MGI:1917184])

HSP 1 Score: 71.633 bits (174), Expect = 6.855e-13
Identity = 52/208 (25.00%), Postives = 98/208 (47.12%), Query Frame = 2 
Query:  497 KIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSI 1105
            K   K++L  A   +  ++  D      M+++++  L+ Q +  Y  NK    PF + LT     S  Y +  +   G          F  +   + E+    ++P + L+YL+PDS+  L+  + D   +YV+G +VD   QK +T  KAR   ++   LP+ +++  +Q  +      L +N  F I+S   ET  +W +A+++ +
Sbjct:  111 KALTKEKLLEAKH-SGPRLCVDLSMTQHMSKKELSRLAGQIRRLYGSNKKASRPFWICLTGFSTASPLYEECLRMNDG----------FSAYLLDVTEEDCFSLFPLETLVYLTPDSEHSLE--DIDQSTVYVIGGLVDESIQKKVTFQKAREYSVKTARLPIQEYMIKRQNEKNYHSEILAINQVFDILSTYFETR-NWPEALKKGV 304
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Mouse
Match: Trmt10b (tRNA methyltransferase 10B [Source:MGI Symbol;Acc:MGI:1917184])

HSP 1 Score: 71.2478 bits (173), Expect = 7.774e-13
Identity = 52/208 (25.00%), Postives = 98/208 (47.12%), Query Frame = 2 
Query:  497 KIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSI 1105
            K   K++L  A   +  ++  D      M+++++  L+ Q +  Y  NK    PF + LT     S  Y +  +   G          F  +   + E+    ++P + L+YL+PDS+  L+  + D   +YV+G +VD   QK +T  KAR   ++   LP+ +++  +Q  +      L +N  F I+S   ET  +W +A+++ +
Sbjct:  109 KALTKEKLLEAKH-SGPRLCVDLSMTQHMSKKELSRLAGQIRRLYGSNKKASRPFWICLTGFSTASPLYEECLRMNDG----------FSAYLLDVTEEDCFSLFPLETLVYLTPDSEHSLE--DIDQSTVYVIGGLVDESIQKKVTFQKAREYSVKTARLPIQEYMIKRQNEKNYHSEILAINQVFDILSTYFETR-NWPEALKKGV 302
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7JUX9|MRRP1_DROME (Mitochondrial ribonuclease P protein 1 homolog OS=Drosophila melanogaster OX=7227 GN=trmt10c PE=1 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 1.076e-22
Identity = 76/279 (27.24%), Postives = 135/279 (48.39%), Query Frame = 2 
Query:  329 RKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFG--------KYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYF--MGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGY-RGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 1132
            R KYF +L + +  KE D  KK+++  + +    E   E  +  +  +G        + Y      +   RL  A+   + +++ D  +++ M  R+    ++Q   C++ N+   +PF +   + +  S     L +Y   M N           +FP  ++ K F E++P + L+YL+P  +  L    Y+ D IY+VGA+VD    +PL+L+KA+  GL    LPLD ++QW  G  + L LN    IM   ++T GDW  A++     +++ N+F
Sbjct:  112 RIKYFGYLWQIEMKKEADQRKKAERAKEAERRVAEMRKEREENTHIIYGLGHTSLFLRIYDTTINHWQNNRLTRAMQF-APKMVLDCSYDEHMNNREATYAAKQLMMCFAENRMNDEPFDLHYCNTQMDSRCMQSLQRYIPTMHNP----------EFPINLHSKCFTELFPKQNLVYLTPHCREDLVT--YNPDDIYIVGAMVDTMNNEPLSLAKAKRLGLRMARLPLDRYLQWGSGSGKSLTLNQMINIMLDLKKT-GDWDTALKHVPRRKVVQNEF 376
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. UniProt/SwissProt
Match: sp|A4IHS0|TM10C_XENTR (tRNA methyltransferase 10 homolog C OS=Xenopus tropicalis OX=8364 GN=trmt10c PE=2 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 1.279e-21
Identity = 76/267 (28.46%), Postives = 137/267 (51.31%), Query Frame = 2 
Query:  329 RKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNP----ESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIY-EKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            RKKY  +L+ ++  K N   KK +       +      E++ +  + KN F    + K      + +   A+    Q ++FD  +E +M+R +++    Q       N+   DPF +   SL+  S+ + +L K ++G      A+ N     FV   +K  +E++P ++L+YL+ DS  +L+   +DH  IY++G++VDR  Q  L+L+ A+   L    LPLD +++W  G + L L+   +I+   ++T GDWKKA+   +P+R
Sbjct:  127 RKKYLKYLSVREVMKTNRKEKKKELKESKSKIESLDQLETKEDTPEKKNTFLLHVWDKSIDTMQRWKCVQAMKF-GQPLVFDMVYEKNMSRYELENTVCQLMESEGWNRRSTDPFHIYFCSLQPYSMYHKELVKRYIG------AWDNV----FVTATDKSHVEMFPKEQLVYLTADSPNELK--HFDHTKIYIIGSLVDRCQQTGLSLANAKRLNLATARLPLDRYLKWDVGAKNLTLDQMIRILLCLKDT-GDWKKAL-SFVPNR 378
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7L0Y3|TM10C_HUMAN (tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2)

HSP 1 Score: 88.1965 bits (217), Expect = 3.391e-17
Identity = 67/265 (25.28%), Postives = 126/265 (47.55%), Query Frame = 2 
Query:  329 RKKYFSFLTKKQFSKENDLLKKSQKIP---KWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            +KKY  +L  K+  K+   +KK  K     + K +      E  + KN  F + + +   I +  +   A+    Q ++FD  +E+ M R++++    Q       N+   DPF +   +LK     + +L K +            +        EK  ++++P   +IYL+ DS     +  + HD +YV+G+ VD+  Q   +L+KA+   L    LPLD ++QW+ G + L L+   +I+ +  + +G+W++A+ Q +P R
Sbjct:  129 KKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETTEEDKQKNFLFLRLWDRNMDIAMGWKGAQAMQF-GQPLVFDMAYENYMKRKELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQ---------EKWDKLLLTSTEKSHVDLFPKDSIIYLTADSPN--VMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTLDQMIRIL-LCLKNNGNWQEAL-QFVPKR 379
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q2KI45|TM10C_BOVIN (tRNA methyltransferase 10 homolog C OS=Bos taurus OX=9913 GN=TRMT10C PE=2 SV=2)

HSP 1 Score: 87.8113 bits (216), Expect = 6.170e-17
Identity = 53/191 (27.75%), Postives = 95/191 (49.74%), Query Frame = 2 
Query:  542 SQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
             Q ++FD  ++D M  ++++    Q       N+   DPF +   +LK     Y +L K +            ++       EK  ++++P   +IYL+ DS     +  + HD IY+VG+ VD++ Q   +L+KA+   L    LPLD ++QW  G + L L+   +I+   + T G W++A+ + +PSR
Sbjct:  204 GQPLVFDMAYDDHMKPKELQNAVSQLLESEGCNRRNVDPFHIYFCNLKTGGAYYKELVKRY---------GEKWNKLLLTATEKSHVDLFPKDSIIYLTADSPN--VMTTFKHDKIYIVGSFVDKNMQPGTSLAKAKRLKLATECLPLDKYLQWDTGTKNLTLDQMMRILLCLKNT-GSWEEAL-KFVPSR 381
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q08BM0|TM10B_DANRE (tRNA methyltransferase 10 homolog B OS=Danio rerio OX=7955 GN=trmt10b PE=2 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.879e-16
Identity = 56/209 (26.79%), Postives = 99/209 (47.37%), Query Frame = 2 
Query:  497 KIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSIP 1108
            K   K+RL  A      ++  D    + +T +++  L+ Q +  Y  NK    PF + LT L+  SL Y +            G    F  +   + E+ +  ++P + +IYL+PD+   L+    + D IY++G +VD    K ++ +KA+  G+    LP+D+++  K+  +      L +N  F I+   R+T  DW KA+   IP
Sbjct:   98 KAITKERLEGA-RAAGLRLCVDLSMTEHLTHKEISRLAAQIRRLYGSNKKALQPFHVFLTELQEDSLLYKEC----------VGMNDGFMHYLIDVTEESWFHLFPSEDVIYLTPDASEALE--SVEEDKIYILGGLVDETIHKKISYTKAKELGVRTARLPIDEYMVKKENPKNFHSKILAINQVFDILLTFRDTR-DWTKALMAGIP 292
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. TrEMBL
Match: A0A0R3TCB5 (SAM-dependent MTase TRM10-type domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS4702 PE=4 SV=1)

HSP 1 Score: 181.415 bits (459), Expect = 8.669e-47
Identity = 119/346 (34.39%), Postives = 186/346 (53.76%), Query Frame = 2 
Query:   89 GRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXX-XXXXXXXNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRD-PFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMI 1120
            GR F +S + N  +K+ +  YL +R  PA E+L++L+  D  RL  IK EH   +A G+ VP  L  ++ L  L C +   R +++ F  K    KE    KK+ +I +    +P   ++  QI               +L   L +A   ++Q ++FD   E++M   D K L+RQ    ++ N++ R  PF  + TSL   S  Y  L + F G  + +    +    PF +    F EV  D++LIYLSP++    ++GEYDHDA+YVVG IVD+  ++P+T +KAR  G E   LPL+ +V W+ G + L L     I++ A+ T+GDWK A++Q+IPSR +
Sbjct:   21 GRNFFTSSVRNFSSKITIAPYLLDRTKPAEEILSNLSSNDADRLAYIKAEHSMLVASGKDVPLDLTPLEYLELLCCPSVSARNRFYLFRFKVAKMKEAKRAKKTSRIIEE---SPSEHIQKNQILRMIRSAPIRAHHDDWLIAELRTA-EDSAQTLVFDCSHEEEMRISDQKNLARQLAMAFAHNRTQRPFPFHFMFTSLVPGSNQYKFLEEAF-GIGVPSSRCNSLEVCPFTVRPDHFSEVIKDRRLIYLSPNASRAFEIGEYDHDAVYVVGGIVDKAVRRPVTHAKARRAGWECIRLPLERYVNWRSGNKTLTLVAIHSILATAKATNGDWKTALEQNIPSRFL 361
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. TrEMBL
Match: C1LEP3 (RNA (Guanine-9-) methyltransferase domain containing protein OS=Schistosoma japonicum OX=6182 GN=EWB00_009484 PE=2 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 1.030e-43
Identity = 115/342 (33.63%), Postives = 186/342 (54.39%), Query Frame = 2 
Query:  134 LKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXXXXXXXXXNYF-QRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPES--------EVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLR-DPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVY----PDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYR-GLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            +K+++YL +R + A EVLN LT ED  RLE    E++  L  G  VP  L   ++L+LLC   F  R  +  FL K +   EN   KK++K+       P S        + +  ++  +F+    ++C               ++Q ++FDF FE +M   D+K LS Q     + N+ +R  PF MVL  LK  +  Y  L    +G  ++  + ++ +D P+ I    F + Y    P++ +I LSP+S+   + GEYDH+A YV+GA+VDR  ++P++ + AR  G++  SLPLD +++W  G R  L +N    IM+ A+ET+GDWK+A+ ++IP+R
Sbjct:   24 VKISDYLLDRTVKAEEVLNRLTPEDAERLEFCMTEYRNMLEQGADVPKSLSKKNVLDLLCCTSFTSRANFLKFLFKNEKRIENHHRKKAEKVSVVFERKPASCDRILRMIDEKCVRLHWDFWQASEIRCPD-------------SAQPLLFDFSFESEMRLVDLKSLSNQMTYVLNRNRVMRPHPFNMVLCGLKQGTNQYAFLEDA-LGVNMEGSSIKSLNDLPWTITPNHFSDEYSVHDPEQPVILLSPNSRHTFEAGEYDHNAAYVIGAVVDRAVRRPISSAIARQLGIKCVSLPLDRYLKWGSGRRKTLTINCIHAIMAAAKETNGDWKRALIENIPTR 351
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. TrEMBL
Match: A0A0R3SSJ5 (SAM-dependent MTase TRM10-type domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS8271 PE=4 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 1.756e-43
Identity = 119/344 (34.59%), Postives = 186/344 (54.07%), Query Frame = 2 
Query:   95 FFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXX-XXXXXXXNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRD-PFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMI 1120
            FF + I L   +K+ +  YL +R  PA E+L++LT +D  RL  IK EH   +A G+ VP  L  ++ L  L C +   R +Y+SF  K    KE    K+S +I +     P   ++  QI     G         ++   L +A   ++Q +IFD   E++M   D K L+RQ    +S N++ R  PF  + TSL H +  Y    + F G    +       + PF +  + F EV  D++L+YLSP++    ++GEYDHDA+YVVG IVD+  ++P+T ++A+  G E   LPL+ +V W+ G + L L     I++ A+ T+GDWK A++Q+IPSR +
Sbjct:   24 FFTTRIKL-FSSKIDIAPYLLDRTKPAEEILSNLTSDDAHRLLYIKAEHSMLIARGKEVPLDLTPLEYLELLCCPSLSARNRYYSFRYKVSKKKEAKKAKQSARIIEESSSEP---IQKNQILRMIRGGPIRAHHDDWVIAELRTA-EDSAQTLIFDCSHEEEMRIIDQKNLARQLAMAFSHNRAQRPFPFHFMFTSLVHGTNQYKFFEEAF-GTENSSSRCSGLEECPFTVRSEHFSEVIKDRRLVYLSPNAPRAFEIGEYDHDAVYVVGGIVDKSVRRPITHARAKRAGWECMRLPLERYVNWRSGSKTLTLVAIHSILATAKATNGDWKVALEQNIPSRFL 361
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. TrEMBL
Match: A0A564Y2E3 (SAM-dependent MTase TRM10-type domain-containing protein (Fragment) OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS2245 PE=4 SV=1)

HSP 1 Score: 171.785 bits (434), Expect = 2.349e-43
Identity = 119/344 (34.59%), Postives = 186/344 (54.07%), Query Frame = 2 
Query:   95 FFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXX-XXXXXXXNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRD-PFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMI 1120
            FF + I L   +K+ +  YL +R  PA E+L++LT +D  RL  IK EH   +A G+ VP  L  ++ L  L C +   R +Y+SF  K    KE    K+S +I +     P   ++  QI     G         ++   L +A   ++Q +IFD   E++M   D K L+RQ    +S N++ R  PF  + TSL H +  Y    + F G    +       + PF +  + F EV  D++L+YLSP++    ++GEYDHDA+YVVG IVD+  ++P+T ++A+  G E   LPL+ +V W+ G + L L     I++ A+ T+GDWK A++Q+IPSR +
Sbjct:   23 FFTTRIKL-FSSKIDIAPYLLDRTKPAEEILSNLTSDDAHRLLYIKAEHSMLIARGKEVPLDLTPLEYLELLCCPSLSARNRYYSFRYKVSKKKEAKKAKQSARIIEESSSEP---IQKNQILRMIRGGPIRAHHDDWVIAELRTA-EDSAQTLIFDCSHEEEMRIIDQKNLARQLAMAFSHNRAQRPFPFHFMFTSLVHGTNQYKFFEEAF-GTENSSSRCSGLEECPFTVRSEHFSEVIKDRRLVYLSPNAPRAFEIGEYDHDAVYVVGGIVDKSVRRPITHARAKRAGWECMRLPLERYVNWRSGSKTLTLVAIHSILATAKATNGDWKVALEQNIPSRFL 360
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. TrEMBL
Match: A0A0R3W6I5 (SAM-dependent MTase TRM10-type domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS5811 PE=4 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 3.075e-42
Identity = 111/344 (32.27%), Postives = 183/344 (53.20%), Query Frame = 2 
Query:  140 VNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXX-XXXXXXXNYFQRKKYFSF---LTKKQFSKENDLLKKSQ---KIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALML---NSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRD-PFQMVLTSLKHQSLTYCDLNKYFMG------NVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMI 1120
            +  YL +R  PA E+L +LT +D  RLE IK EH   ++ G   P  L  +D L  L C +   R +Y+ F   ++KK+ +++  ++ K++   K+P          VE TQ KN           +++    + + L     ++Q ++FD   E +M   D K L+RQ    ++ N+++R  PF  + TSL   +  Y    + F        + L++G  R+  + PF +  + F EV   +KLIYLSP++    + GE+DHD  +VVG IVD+  ++P+T ++AR  G E   LPL+ +V W+ G + L L     I++ A+ T+GDWK A++Q+IPSR +
Sbjct:   16 IAPYLLDRTRPAEEILKNLTPDDAQRLEYIKAEHNMLISTGRPAPLNLSALDYLELLCCTSVSARNRYYMFRFKISKKKDARKAKMMAKTEDECKLP----------VELTQ-KNQILRMITSTPIRMHNDDWVVAELRTADDSAQTLVFDCSHESEMRIMDQKNLARQMAMAFAHNRTIRPFPFHFMFTSLVPGTNQYRFFEEAFGACSSGGFSNLQSGGLRSLEECPFTVRSEHFAEVMKGRKLIYLSPNASRAFENGEFDHDVTFVVGGIVDKAIRRPVTYARARRAGWECMRLPLERYVHWRSGNKTLTLVTIHAILATAKATNGDWKAALEQNIPSRFL 348
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Cavefish
Match: trmt10c (tRNA methyltransferase 10C, mitochondrial RNase P subunit [Source:ZFIN;Acc:ZDB-GENE-041114-12])

HSP 1 Score: 101.679 bits (252), Expect = 1.895e-22
Identity = 62/217 (28.57%), Postives = 105/217 (48.39%), Query Frame = 2 
Query:  452 QIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDL--NKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQ 1096
            ++KN F  K++ +     L  R   A M   Q ++FD  +E  M+  D K    Q   C   N+   DPF           L +C+L  N  +   +LK      +         +  ++++P + L+YL+ DS   L+   +DH+ +Y++GA VDR  Q  ++L+ A+   L    LPL++ +QW  G + L L+   QI+   +ET G W+KA++
Sbjct:  189 KLKNTFLMKFWSRSLDTLLFWRSAQA-MQYGQPLVFDMSYEQHMSSHDAKNTVSQLLQCEGWNRRSVDPFH----------LHFCNLQPNSVYHQELLKRYGQETWERLFITTTSQRHVDIFPRENLVYLTADSPNVLR--TFDHNKVYIIGAFVDRSAQSGVSLANAKRLKLATARLPLNEHLQWDCGAKNLTLDQMIQILITIKET-GSWEKALE 391
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Cavefish
Match: trmt10b (tRNA methyltransferase 10B [Source:NCBI gene;Acc:103041922])

HSP 1 Score: 84.7297 bits (208), Expect = 2.294e-17
Identity = 55/210 (26.19%), Postives = 105/210 (50.00%), Query Frame = 2 
Query:  497 KIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSIPS 1111
            K   ++RL  A   +  ++  D    D M+ +++  L+ Q +  Y  NK    PF + L+ LK   L Y +  +   G          F ++   + E+ +I+++P + ++YLSPD+   L+    D D +Y++G +VD   QK ++ ++A+  G+    LP+D+++  K   +      L +N  F+I+   R+T G+W  A+   IP+
Sbjct:  102 KAITRERLEEA-RTSGPRLCVDLSMTDCMSHKEISRLAGQIRRLYGSNKKALQPFHLFLSDLKKDGLLYRECIRMNDG----------FLNYMIDVTEESWIDLFPSQDIVYLSPDASEALE--RVDEDKVYILGGLVDESIQKKISYTRAKELGVYMARLPIDEYMVKKPNPKNFHSKILAINQVFEILLKFRDT-GNWITALGAGIPA 297
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Cavefish
Match: trmt10a (tRNA methyltransferase 10A [Source:NCBI gene;Acc:103028907])

HSP 1 Score: 78.5666 bits (192), Expect = 2.643e-15
Identity = 58/190 (30.53%), Postives = 95/190 (50.00%), Query Frame = 2 
Query:  548 QIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCD-LNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            +++ D  F+  M  +DVK+L +Q Q CY+ N+    P Q  +TS   Q     D +NK ++        +++ H  P     + F EV     L+YL+ DS   L+  E D +  YV+G +VD +  K ++  +A+  G+ H  LPL  FV+     + L +N  F+I+ +A     DWK+A    +P R
Sbjct:   97 RLVVDCSFDSLMLLKDVKKLHKQIQRCYAENRRAAHPVQFYITSHGGQLKQNMDEINKGWVN-------WKDVHIKP-----EHFHEVLSKDDLVYLTSDSPNVLE--ELDENKAYVIGGLVDHNHHKGISFERAKELGIAHAQLPLSSFVKMN-SRKVLAVNHVFEIL-LAYLEKRDWKEAFFTVLPQR 270
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Yeast
Match: TRM10 (tRNA methyltransferase; methylates the N-1 position of guanine at position 9 in tRNAs; protein abundance increases in response to DNA replication stress; member of the SPOUT (SpoU-TrmD) methyltransferase family; human ortholog TRMT10A plays a role in the pathogenesis of microcephaly and early onset diabetes; an 18-mer originates from the TRM10 locus; genetic analysis shows the 18-mer is the translation regulator [Source:SGD;Acc:S000005453])

HSP 1 Score: 64.6994 bits (156), Expect = 8.570e-12
Identity = 53/193 (27.46%), Postives = 93/193 (48.19%), Query Frame = 2 
Query:  548 QIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFI--EVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMI 1120
            +II D  F++ M  +++  LS Q    YS N+      ++ +     +      L + F    LK   Y N++ F F+  +K     E     K++YL+ D++ KL+  + +    Y+VG IVD++  K L L KA+  G+  R LP+D+++   +G R L      Q+M +      +WK A +  +P R +
Sbjct:   96 EIILDCSFDELMNDKEIVSLSNQVTRAYSANRRANHFAEIKVAPFDKR------LKQRF-ETTLKNTNYENWNHFKFLPDDKIMFGDEHISKDKIVYLTADTEEKLE--KLEPGMRYIVGGIVDKNRYKELCLKKAQKMGIPTRRLPIDEYINL-EGRRVLTTTHVVQLM-LKYFDDHNWKNAFESVLPPRKL 277
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Nematostella
Match: EDO37892 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEK2])

HSP 1 Score: 86.2705 bits (212), Expect = 7.219e-19
Identity = 57/189 (30.16%), Postives = 96/189 (50.79%), Query Frame = 2 
Query:  548 QIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            +I+ D  F+D M+ RD+ +L +Q Q CY++N+    P QM LTS + +S +  D            G + +  D    I  +   +V+P + +IYL+ DS     L E D   +YV+G +VD +  K     +A  +G +H  LP+ +F++     + L +N  F+I+ +    S DWK+A    +P R
Sbjct:   65 RIVIDLNFDDLMSDRDMLKLMKQVQRCYAVNRRADHPVQMYLTSFEGKSRSRLD----------HIGCHYDRWDVN--IKSEHLTKVFPKEDIIYLTSDSPN--MLTELDMSKVYVIGGLVDHNHHKGYCYDQAVKQGFQHAQLPIGEFIKIAT-RKVLTVNHVFEIL-VRYCESKDWKEAFFHVMPQR 237
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Nematostella
Match: EDO46382 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQK9])

HSP 1 Score: 62.7734 bits (151), Expect = 3.532e-11
Identity = 50/203 (24.63%), Postives = 85/203 (41.87%), Query Frame = 2 
Query:  533 MLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQG-----YRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFN 1126
            M N  ++  D      M+++++ +++ Q +  Y  N     P  +  T L      Y +  +   G          F  +     E    +V+   + IYL+PDS   L+    D   +YV+G +VD    K +T  KA    L+   LPLD+++           R L +N  F I+    ET  DW++A+   +P+R  F 
Sbjct:    1 MTNGLRVALDLSLVHKMSKKEIGKVAGQVRRVYGSNMKSSRPVHLHFTGLVKSEAIYQECVRQNQG----------FEQYMVEKTECSLSDVFAADETIYLTPDSPNVLE--SLDSRMVYVIGGLVDHTVLKNVTKRKAEVCSLKTARLPLDEYMDMVHSGNHNYSRVLSINQVFDILLKFYETK-DWRQALLSGVPARKGFT 190
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Medaka
Match: trmt10c (tRNA methyltransferase 10C, mitochondrial RNase P subunit [Source:NCBI gene;Acc:101173046])

HSP 1 Score: 105.916 bits (263), Expect = 1.482e-23
Identity = 75/263 (28.52%), Postives = 132/263 (50.19%), Query Frame = 2 
Query:  329 RKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPE--------SEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAI 1093
            RKKY  +L  ++  K +   K++QK  + +    E        S+ E  QI N+ F K++          R   A ML  Q ++FDF +E +M+RR+++    Q       N+   DPF +   +L+     + +L K +   V        +        E+ ++E++P ++L+YL+ DS   L    +DH  IY++GA+VDR  Q  L+L+ A+   L    LPLD+F+ W+ G + L L+   +IM ++ + +G W++A+
Sbjct:  152 RKKYLKYLAIREGYKLSRKEKQAQKRAEKEATMKENRGGAEEGSDQENNQIPNSLFLKFWGHSFDRVFAWRSAQA-MLFGQPLVFDFSYESNMSRREIENTVSQLLEVEGWNRRAIDPFHLHFCNLQPDGPYHQELIKRYSAEV--------WDRLLVTNTERHYVELFPKEQLVYLTADSPNVLH--SFDHSKIYIIGALVDRSIQPGLSLANAKRLKLATARLPLDEFLHWETGAKNLTLDQMIRIM-LSIKMTGKWEEAL 402
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Medaka
Match: trmt10a (tRNA methyltransferase 10A [Source:NCBI gene;Acc:101158639])

HSP 1 Score: 86.6557 bits (213), Expect = 3.620e-18
Identity = 63/204 (30.88%), Postives = 100/204 (49.02%), Query Frame = 2 
Query:  503 YLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSR 1114
            + ++R       +S +++ D  F+  M  +DV++L +Q Q CY+ N+    P Q  LTS+  Q     D          K G + N+ D    I  + + EV   + L+YL+ DS   L+  E DH+  YV+G +VD +  K +T  KA+  G+EH  LPL  FV+     + L +N  F+I+    E S  W+ A    +P R
Sbjct:   75 HARKRFRREATPSSLRLVVDCSFDSLMLAKDVQKLHKQIQRCYAENRRAAHPVQFYLTSMGGQLQQSMDE---------KDGGWVNWKDI--RIQTEHYSEVIGKEDLVYLTSDSPNVLK--ELDHNKAYVIGGLVDHNHHKGITFEKAKELGIEHAQLPLSAFVRMN-SRKVLAVNHVFEIILAFLEKSS-WQDAFFTVLPQR 263
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Medaka
Match: trmt10b (tRNA methyltransferase 10B [Source:NCBI gene;Acc:101156045])

HSP 1 Score: 80.1073 bits (196), Expect = 8.440e-16
Identity = 60/210 (28.57%), Postives = 99/210 (47.14%), Query Frame = 2 
Query:  497 KIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRG-----LPLNICFQIMSIARETSGDWKKAIQQSIPS 1111
            K   K+RL  A      ++  D    D M+ +++  L+ Q +  Y  NK    PF + LT L   S  Y +  +   G          F ++   I EK  +E++  + ++YL+PD++  L+    D D +YV+G +VD   QK L+LSKA    +    LP+D+++  K   +      L +N  F I+    E SG W K++Q   P+
Sbjct:   94 KAITKERLADA-QSTGLKLCVDLSMTDRMSDKEISRLAGQLRRLYGSNKKATWPFHVFLTDLGEDSRLYRECIRMNDG----------FLNYMMDITEKGVLELFSPESVVYLTPDAEEALET--VDPDKVYVLGGLVDESIQKKLSLSKASDLSVRTARLPIDEYMIKKDNVKNFHSKILAINQVFDILLTFFE-SGSWTKSLQAWFPA 289
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Planmine SMEST
Match: SMESG000075125.1 (SMESG000075125.1)

HSP 1 Score: 736.487 bits (1900), Expect = 0.000e+0
Identity = 372/372 (100.00%), Postives = 372/372 (100.00%), Query Frame = 2 
Query:   17 MPKMCNMLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXXXXXXXXXNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 1132
            MPKMCNMLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPDLLRDVDLLELLCLNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF
Sbjct:    1 MPKMCNMLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPDLLRDVDLLELLCLNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 372
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Planmine SMEST
Match: SMESG000075125.1 (SMESG000075125.1)

HSP 1 Score: 730.709 bits (1885), Expect = 0.000e+0
Identity = 369/369 (100.00%), Postives = 369/369 (100.00%), Query Frame = 2 
Query:   26 MCNMLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXXXXXXXXXNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 1132
            MCNMLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPDLLRDVDLLELLCLNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF
Sbjct:    1 MCNMLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPDLLRDVDLLELLCLNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 369
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Planmine SMEST
Match: SMESG000075125.1 (SMESG000075125.1)

HSP 1 Score: 723.776 bits (1867), Expect = 0.000e+0
Identity = 366/366 (100.00%), Postives = 366/366 (100.00%), Query Frame = 2 
Query:   35 MLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXXXXXXXXXNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 1132
            MLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPDLLRDVDLLELLCLNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF
Sbjct:    1 MLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPDLLRDVDLLELLCLNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 366
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Planmine SMEST
Match: SMESG000075125.1 (SMESG000075125.1)

HSP 1 Score: 661.374 bits (1705), Expect = 0.000e+0
Identity = 336/336 (100.00%), Postives = 336/336 (100.00%), Query Frame = 2 
Query:  125 MNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXXXXXXXXXNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 1132
            MNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPDLLRDVDLLELLCLNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF
Sbjct:    1 MNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPDLLRDVDLLELLCLNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMIFNKF 336
[Close]
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Planmine SMEST
Match: SMESG000075138.1 (SMESG000075138.1)

HSP 1 Score: 321.242 bits (822), Expect = 1.539e-102
Identity = 174/359 (48.47%), Postives = 241/359 (67.13%), Query Frame = 2 
Query:   50 FKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRAIPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPXXXXXXXXXXXXXXNYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNNFFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQFQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNK--YFMGNVLKTGAYRNFHDFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDRDGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARETSGDWKKAIQQSIPSRMI 1120
             KN   C    K GR  H+S +LN+ + +K+N+YL NR +PATE+LNSL  ED  RL+ IK   +  LA G +VP  + D   LELLCL+  Q+ KY  FL KK+F  E+D LKK  K+ K   LN ++ +  T I N F  KY+   EK  +  R++ A+ L SQ+IIFD  FE+DM+RR+V EL++Q   CYS+N+ L++PFQMV  +L++ SLTY D  K  + MG++ +      F D P +I +K + E+YPD+KLIYLSPDS    + GEYDH+AIY++G +VD+  Q P+T++KAR E LE R +PLD +V W+QG RGLPLN  F IMSIARET+G+W+KAI++SI +R +
Sbjct:   14 LKNVLEC----KLGRHLHNSSILNVRSFVKINDYLLNRMVPATEILNSLQLEDSARLDLIKRNIEFKLANGSLVPKKISDEQYLELLCLSRGQQNKYLEFLAKKEFKSESDSLKKKYKLQKNINLNSDNPL-TTNITNRFISKYHNLAEKRLINNRMYQAITLKSQEIIFDLSFENDMSRREVGELAKQLFYCYSLNRLLKEPFQMVFVNLEYGSLTYSDARKSLFTMGSLCEK-----FEDLPIIIQQKSYFEMYPDRKLIYLSPDSSQYFKEGEYDHEAIYIIGGLVDKAYQNPMTIAKARRENLETRCIPLDRYVDWQQGSRGLPLNHVFNIMSIARETNGNWEKAIRESIAARSL 362
The following BLAST results are available for this feature:
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TRMT10C7.061e-1825.28tRNA methyltransferase 10C, mitochondrial RNase P ... [more]
TRMT10A1.629e-1430.20tRNA methyltransferase 10A [Source:HGNC Symbol;Acc... [more]
TRMT10A1.629e-1430.20tRNA methyltransferase 10A [Source:HGNC Symbol;Acc... [more]
TRMT10A1.629e-1430.20tRNA methyltransferase 10A [Source:HGNC Symbol;Acc... [more]
TRMT10B3.964e-1325.39tRNA methyltransferase 10B [Source:HGNC Symbol;Acc... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
F46F11.106.027e-1728.75pep chromosome:WBcel235:I:5623019:5624475:-1 gene:... [more]
F25H8.17.874e-1527.37pep chromosome:WBcel235:IV:9930899:9932240:-1 gene... [more]
F25H8.18.447e-1527.37pep chromosome:WBcel235:IV:9930899:9932213:-1 gene... [more]
C56G2.31.436e-1127.96pep chromosome:WBcel235:III:6346285:6348121:1 gene... [more]
C56G2.31.436e-1127.96pep chromosome:WBcel235:III:6346285:6348121:1 gene... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rswl1.074e-2327.24gene:FBgn0034351 transcript:FBtr0086696[more]
CG146182.046e-824.76gene:FBgn0031189 transcript:FBtr0077351[more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trmt10c5.433e-1824.64tRNA methyltransferase 10C, mitochondrial RNase P ... [more]
trmt10b2.269e-1727.27tRNA methyltransferase 10B [Source:NCBI gene;Acc:7... [more]
trmt10b2.269e-1727.27tRNA methyltransferase 10B [Source:NCBI gene;Acc:7... [more]
trmt10b2.269e-1727.27tRNA methyltransferase 10B [Source:NCBI gene;Acc:7... [more]
trmt10c1.585e-1626.04tRNA methyltransferase 10C, mitochondrial RNase P ... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
trmt10c2.306e-2228.46tRNA methyltransferase 10C, mitochondrial RNase P ... [more]
TRMT10B1.976e-1626.64tRNA methyltransferase 10B [Source:NCBI gene;Acc:1... [more]
TRMT10B3.508e-1627.32tRNA methyltransferase 10B [Source:NCBI gene;Acc:1... [more]
trmt10a1.190e-1529.90tRNA methyltransferase 10A [Source:NCBI gene;Acc:4... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Trmt10a9.099e-1730.69tRNA methyltransferase 10A [Source:MGI Symbol;Acc:... [more]
Trmt10a9.099e-1730.69tRNA methyltransferase 10A [Source:MGI Symbol;Acc:... [more]
Trmt10c6.473e-1525.65tRNA methyltransferase 10C, mitochondrial RNase P ... [more]
Trmt10b6.855e-1325.00tRNA methyltransferase 10B [Source:MGI Symbol;Acc:... [more]
Trmt10b7.774e-1325.00tRNA methyltransferase 10B [Source:MGI Symbol;Acc:... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7JUX9|MRRP1_DROME1.076e-2227.24Mitochondrial ribonuclease P protein 1 homolog OS=... [more]
sp|A4IHS0|TM10C_XENTR1.279e-2128.46tRNA methyltransferase 10 homolog C OS=Xenopus tro... [more]
sp|Q7L0Y3|TM10C_HUMAN3.391e-1725.28tRNA methyltransferase 10 homolog C OS=Homo sapien... [more]
sp|Q2KI45|TM10C_BOVIN6.170e-1727.75tRNA methyltransferase 10 homolog C OS=Bos taurus ... [more]
sp|Q08BM0|TM10B_DANRE1.879e-1626.79tRNA methyltransferase 10 homolog B OS=Danio rerio... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3TCB58.669e-4734.39SAM-dependent MTase TRM10-type domain-containing p... [more]
C1LEP31.030e-4333.63RNA (Guanine-9-) methyltransferase domain containi... [more]
A0A0R3SSJ51.756e-4334.59SAM-dependent MTase TRM10-type domain-containing p... [more]
A0A564Y2E32.349e-4334.59SAM-dependent MTase TRM10-type domain-containing p... [more]
A0A0R3W6I53.075e-4232.27SAM-dependent MTase TRM10-type domain-containing p... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
trmt10c1.895e-2228.57tRNA methyltransferase 10C, mitochondrial RNase P ... [more]
trmt10b2.294e-1726.19tRNA methyltransferase 10B [Source:NCBI gene;Acc:1... [more]
trmt10a2.643e-1530.53tRNA methyltransferase 10A [Source:NCBI gene;Acc:1... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
TRM108.570e-1227.46tRNA methyltransferase; methylates the N-1 positio... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO378927.219e-1930.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO463823.532e-1124.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
trmt10c1.482e-2328.52tRNA methyltransferase 10C, mitochondrial RNase P ... [more]
trmt10a3.620e-1830.88tRNA methyltransferase 10A [Source:NCBI gene;Acc:1... [more]
trmt10b8.440e-1628.57tRNA methyltransferase 10B [Source:NCBI gene;Acc:1... [more]
back to top
BLAST of SAM-dependent MTase TRM10-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000075125.10.000e+0100.00SMESG000075125.1[more]
SMESG000075125.10.000e+0100.00SMESG000075125.1[more]
SMESG000075125.10.000e+0100.00SMESG000075125.1[more]
SMESG000075125.10.000e+0100.00SMESG000075125.1[more]
SMESG000075138.11.539e-10248.47SMESG000075138.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005144 ID=SMED30005144|Name=SAM-dependent MTase TRM10-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2356bp
GTTATAAAACTTTGAAATGCCCAAAATGTGCAATATGCTTTACGCATCAT
TTAAAAATAAATTTGTTTGTGATTATTTATTTAAACCTGGTAGATTTTTT
CACAGCTCTATATTGCTAAATATTATGAACAAATTGAAAGTAAATGAATA
TTTATTCAATAGAGCTATTCCAGCAACTGAAGTTTTGAATTCATTAACCG
AGGAAGACAAGATACGTTTAGAAAATATAAAAATGGAACACCAAACTTAT
TTAGCATTGGGTGAAATTGTTCCGGATTTATTAAGGGATGTTGATCTATT
AGAACTTTTATGTTTAAATTATTTCCAGAGAAAAAAATATTTTTCTTTTT
TAACAAAAAAACAATTTTCCAAAGAGAATGATCTTTTGAAAAAGTCACAG
AAAATTCCTAAATGGAAGATCTTAAACCCAGAAAGTGAAGTAGAAGCAAC
TCAAATAAAGAATAATTTTTTTGGCAAATATTACATGAAATGTGAAAAAA
TATATCTCAAGCAAAGATTGTTTAGTGCGTTGATGCTAAACTCACAGCAA
ATCATATTCGATTTTGGTTTTGAAGATGATATGACCAGGCGTGACGTAAA
AGAACTTTCTAGACAATTTCAATGTTGTTATTCTATTAACAAAAGCTTAA
GAGATCCATTTCAAATGGTTTTAACTAGTTTGAAACACCAAAGTCTTACA
TATTGTGATCTTAATAAATACTTTATGGGAAATGTGTTGAAAACTGGCGC
ATACAGGAATTTTCACGATTTTCCATTTGTTATTTATGAAAAGCCTTTCA
TTGAGGTTTATCCCGATAAAAAATTGATTTATCTTTCTCCTGATTCTAAA
ATGAAATTACAGCTCGGTGAATATGACCACGATGCGATATATGTAGTCGG
GGCTATCGTGGACAGAGATGGTCAGAAACCCCTTACACTATCCAAGGCCA
GACATGAGGGCCTGGAGCATCGCTCTCTCCCACTTGATGATTTCGTCCAA
TGGAAACAAGGCTACAGGGGATTGCCATTAAACATATGTTTCCAGATTAT
GTCCATCGCCAGGGAAACCTCTGGCGATTGGAAAAAGGCAATTCAGCAAA
GTATTCCCTCGAGGATGATTTTCAATAAATTTTAAACTGATGTATTCTTA
CGCTGGTTCCATTTCGATAACGGTTTGTGCAAATCGAATGAAAAGTTGCA
CGTAATAAATTATAATTAGTATAAAGATCAATATTTCGGTGTCAAACAGA
TTGCAAGTATTGATCTGAGTATTTATATTTTAAAAAAACCAAACAATTAA
TTCTTTAGTTGGTCAACTAAAAATGAATAATTTAGTTAGATTTTAATCTT
TGAATGTGAATCGTTCAAAATATGAGATCTGGAAATGCGGTTGTTTTATT
GTGCTAACTGATGACCTTGATAAATTATTATCATTACTCAGAATTGCTTT
ACTACAGCTAATAAAATACAGTAATAAAAATTTTCTATTTTGAAATGTAT
TGCGAGATGATCTATCTAATCGGATGAAGCGTACGAAATGATTGGATGAT
GGAAATCATATACACCAACTGTTGGTGACTAACAGAAAGACTGCTACATA
AACAATAATAGATTAATTTCACATAGTGTAAGTGTTTGAATAATTACACG
CGTTATCTTTATAAGATAATACTCAAGAAGATTTCCTACGTACTCACTCT
AAAAGTAATCCTATCAGAAATAGGCACATTAGAATTGTGCTCAAACTAGC
AGTGATAAGTATGAGGTGATATAAAAGTTAACTCTGTAAGATAACAACCG
GAATAAAGCAAATGAAATATCGAGTGCGCAGCCAATGAAATAAAAAGCTG
AGCATTAGTGAAGATTTTCTCGTATACGTAGATAAACAACGAATCAATCA
TACAGCTAACAACTTATTGAATAAACGATACGTGCTATTGAAAAACTTCA
TTGCTTAGACGGATGATTGTACAACAACTGAACACAATATTATTGCAACA
ACCAACCTTAATCTCATCCTCAATTAAAAAACTAATATCTAACTATGGAA
ATCTGGAAAAAGAAAATTACGAACCATTAAAATAAATGGAAAATTTAAAT
GAAATAATGCTTAAAAATAATAAAATCACTGATCAAATTTTTACAGAAAA
TACCAAAGATATTTTTCGAGATCGAACATTTAAACACTAAAAACTTGAAA
CTTATTGTCGACGGAAGACCTATGCTCGCTTTGTGATGTCCCCTGTGTGC
GAAGGTCCAAGATCAGACTCATGTTGGTAGGTAAAGATGGAACGACATTA
ATCTGACGAAGCGTGAATGCTCATGACCTTTCTGTAGCAATTAAATATTA
TTCCCA
back to top

protein sequence of SMED30005144-orf-1

>SMED30005144-orf-1 ID=SMED30005144-orf-1|Name=SMED30005144-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=373bp
MPKMCNMLYASFKNKFVCDYLFKPGRFFHSSILLNIMNKLKVNEYLFNRA
IPATEVLNSLTEEDKIRLENIKMEHQTYLALGEIVPDLLRDVDLLELLCL
NYFQRKKYFSFLTKKQFSKENDLLKKSQKIPKWKILNPESEVEATQIKNN
FFGKYYMKCEKIYLKQRLFSALMLNSQQIIFDFGFEDDMTRRDVKELSRQ
FQCCYSINKSLRDPFQMVLTSLKHQSLTYCDLNKYFMGNVLKTGAYRNFH
DFPFVIYEKPFIEVYPDKKLIYLSPDSKMKLQLGEYDHDAIYVVGAIVDR
DGQKPLTLSKARHEGLEHRSLPLDDFVQWKQGYRGLPLNICFQIMSIARE
TSGDWKKAIQQSIPSRMIFNKF*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR038459MT_TRM10-typ_sf
IPR025812TRM10C
IPR007356tRNA_m1G_MeTrfase_euk
IPR016009tRNA_MeTrfase_TRMD/TRM10
IPR028564MT_TRM10-typ
Vocabulary: cellular component
TermDefinition
GO:0005739mitochondrion
Vocabulary: biological process
TermDefinition
GO:0008033tRNA processing
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR016009tRNA methyltransferase TRMD/TRM10-type domainPFAMPF01746tRNA_m1G_MTcoord: 188..366
e-value: 9.9E-17
score: 61.3
IPR038459tRNA methyltransferase TRM10-type domain superfamilyGENE3DG3DSA:3.40.1280.30coord: 160..367
e-value: 1.9E-46
score: 160.2
IPR025812tRNA methyltransferase 10 homologue CPANTHERPTHR13563:SF5TRNA METHYLTRANSFERASE 10 HOMOLOG Ccoord: 57..367
IPR007356tRNA (guanine-N1-)-methyltransferase, eukaryoticPANTHERPTHR13563TRNA (GUANINE-9-) METHYLTRANSFERASEcoord: 57..367
IPR028564tRNA methyltransferase TRM10-type domainPROSITEPS51675SAM_MT_TRM10coord: 164..370
score: 36.177
NoneNo IPR availableCDDcd18102Trm10_MRRP1coord: 177..366
e-value: 5.59791E-57
score: 181.967