Voltage-dependent L-type calcium channel subunit alpha
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30005127 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 16Note: Hover over icons to view figure legend
Homology
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1S (calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397]) HSP 1 Score: 1634 bits (4230), Expect = 0.000e+0 Identity = 930/1751 (53.11%), Postives = 1172/1751 (66.93%), Query Frame = 1
Query: 958 GGRKRTPARSQSGN-PRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----------SEG-GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMM----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNET-SRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGK----ENGK--ESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNG--DIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQ---TSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAP 6120
G RK+ P + PRP RALFCLTL NP RK CI IVEWKPFE +IL TIFANC ALA P PE D+N++N LEK+E F+++F+ E +KI+A+GF+ H AYLR+GWN+LDF IV +G+ + +L ++ S+G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI +AM+PLFHIALL LF++IIYAIIGLELF GK+H TCY D++ E P PC+ +G C N +E W GPN GIT FDNFG +MLTV+QCITMEGWT ++YW+ND++G WPWIYFV+LI++GSFF++NLVLGVLSGEF+KEREKAK RG +QK RE+ Q DED++GY+ WI E + ++ +GK E G ES +++ GL K + H +Q +F + +VKS+ FYW+VI++V LNT + SEH+ Q +WL Q+ AN + + LFT EML+KMY LG+R YF +FNRFD FVV ILEI+++++ AM PLG+SVLRC RLLR+FK+T+YW+SL NLV SLL S++SI SLL+LLFLFIVIF+LLGMQLFGG+++F+ RSNFD+F Q+L++VFQ+LTGEDW +MY+GI +YG ML C+Y++ILF+CGNYILLNVFLAIAVDNLA+ S EE K S P+ E+ + T A++L + + G A + + + ++ K+ +++E+ + + R ++E+ KEK PIP ASSFFIF P NK R CH I N F N +L+ I++SSA LAAEDP+ A+S RN+IL +FD FTSVFTVEI LK+ TYG H G+FCR+ N+LDLLVV S+IS + + AISVVKILRVLRVLRPLRAINRAKGLK VVQC+ VA+ +IGNI+LVT LL+FMFA IGVQLF GKF C D+SK T CRG Y Y + D ++ + REW+++ +FDNV +AM++LF VSTFEGWP +LYK+IDS ED IYNNR ++IF+I YII+IAFFM+NIFVGFVIVTFQ++GE EYKNCELDKNQR+C+++ALKA+P+R YIPK ++Y+VW+++TS FEY++F LIMLNTI L ++ Q ++ + D LN+ FT +FT+E +LKL AF + YF D WNVFDF+IV+GS ID+I ++ + + R IS FFRLFRVMRL+KLLSR EG+RTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ I+L C +CD SD E Y CG+NFAY YFISFYM+C+FL+INLFVAVIMDNFDYLTRDWSILGPHHLDEF +W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK+CPHR AC LV MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IKKIWKRTS K+LDQV+PP G+D+VTVGKFYATFLIQE FR++ KR EE G + RT + P I + E E+ G RRT +FG + N L+R S LP +N RP+ + + PV L P
Sbjct: 10 GLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEEPSPCA-------------RTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDEDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIAGLNKIIQFI-------------------RHWRQWNRIFRWKCHD----------------IVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSA------------QKAKAEEKKRRKMSKGLPDKSEEEKSTMAKKLEQKPKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDESAR----ISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEYT-------------------------------------------CGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPKKDIVQIQAGLRTIEEEAAPEICRTVSGDLAAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNS-------------------LPPVMANQRPLQFAEIEMEEMESPVFLEDFP 1629
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1S (calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397]) HSP 1 Score: 1624.37 bits (4205), Expect = 0.000e+0 Identity = 930/1766 (52.66%), Postives = 1171/1766 (66.31%), Query Frame = 1
Query: 958 GGRKRTPARSQSGN-PRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----------SEG-GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMM----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNET-SRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGK----ENGK--ESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNG--DIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQ---TSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNG---------------TNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAP 6120
G RK+ P + PRP RALFCLTL NP RK CI IVEWKPFE +IL TIFANC ALA P PE D+N++N LEK+E F+++F+ E +KI+A+GF+ H AYLR+GWN+LDF IV +G+ + +L ++ S+G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI +AM+PLFHIALL LF++IIYAIIGLELF GK+H TCY D++ E P PC+ +G C N +E W GPN GIT FDNFG +MLTV+QCITMEGWT ++YW+ND++G WPWIYFV+LI++GSFF++NLVLGVLSGEF+KEREKAK RG +QK RE+ Q DED++GY+ WI E + ++ +GK E G ES +++ GL K + H +Q +F + +VKS+ FYW+VI++V LNT + SEH+ Q +WL Q+ AN + + LFT EML+KMY LG+R YF +FNRFD FVV ILEI+++++ AM PLG+SVLRC RLLR+FK+T+YW+SL NLV SLL S++SI SLL+LLFLFIVIF+LLGMQLFGG+++F+ RSNFD+F Q+L++VFQ+LTGEDW +MY+GI +YG ML C+Y++ILF+CGNYILLNVFLAIAVDNLA+ S EE K S P+ E+ + T A++L + + G A + + + ++ K+ +++E+ + + R ++E+ KEK PIP ASSFFIF P NK R CH I N F N +L+ I++SSA LAAEDP+ A+S RN+IL +FD FTSVFTVEI LK+ TYG H G+FCR+ N+LDLLVV S+IS + + AISVVKILRVLRVLRPLRAINRAKGLK VVQC+ VA+ +IGNI+LVT LL+FMFA IGVQLF GKF C D+SK T CRG Y Y + D ++ + REW+++ +FDNV +AM++LF VSTFEGWP +LYK+IDS ED IYNNR ++IF+I YII+IAFFM+NIFVGFVIVTFQ++GE EYKNCELDKNQR+C+++ALKA+P+R YIPK ++Y+VW+++TS FEY++F LIMLNTI L ++ Q ++ + D LN+ FT +FT+E +LKL AF + YF D WNVFDF+IV+GS ID+I ++ N + IS FFRLFRVMRL+KLLSR EG+RTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ I+L C +CD SD E Y CG+NFAY YFISFYM+C+FL+INLFVAVIMDNFDYLTRDWSILGPHHLDEF +W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK+CPHR AC LV MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IKKIWKRTS K+LDQV+PP G+D+VTVGKFYATFLIQE FR++ KR EE G + RT + P I + E E+ G RRT +FG + N L+R S LP +N RP+ + + PV L P
Sbjct: 10 GLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEEPSPCA-------------RTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDEDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIAGLNKIIQFI-------------------RHWRQWNRIFRWKCHD----------------IVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSA------------QKAKAEEKKRRKMSKGLPDKSEEEKSTMAKKLEQKPKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEYT-------------------------------------------CGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPKKDIVQIQAGLRTIEEEAAPEICRTVSGDLAAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNS-------------------LPPVMANQRPLQFAEIEMEEMESPVFLEDFP 1648
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1D (calcium voltage-gated channel subunit alpha1 D [Source:HGNC Symbol;Acc:HGNC:1391]) HSP 1 Score: 975.696 bits (2521), Expect = 0.000e+0 Identity = 542/902 (60.09%), Postives = 658/902 (72.95%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAE----RRTHSIFGTMMNVLQRVGSTRRDS 5985
RR+SE+ KEKI PIP S+FFI N R CH + NH F N++LV IM+SSA LAAEDP+ + S RN IL YFDY FT++FTVEI LK+ T+G H GAFCR+ N+LD+LVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF C D +K+ CRG +I Y + D+ V +R W N+ NFDNV +AM+ LF VSTFEGWP +LYK+IDS E+ IYN+R +SIF+I YII++AFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S PFEY++FVLIMLNT+ LA++ +Q + + MD LNMVFTGVFTVE +LK+ AF K YFSDAWN FD +IV+GS ID+ + + ++R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQMFGK+ ++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP +CD SD E Y CGSNFA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ ++Q NEELR VIKKIWK+TS K+LDQVVPPAG+D+VTVGKFYATFLIQ++FR++K+++ + G +++ ++L RT + I P + CD +D + + E +R ++ G +N V S RRDS
Sbjct: 846 RRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNR----ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAM---RDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYT-------------------------------------------CGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRT--------LHDIGPEIRRAISCDLQDDEPEETKREEEDDVFKRNGALLGNHVN---HVNSDRRDS 1685 HSP 2 Score: 713.375 bits (1840), Expect = 0.000e+0 Identity = 400/693 (57.72%), Postives = 496/693 (71.57%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSE------------GGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMMES-PVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
++ + S N RP RALFCL+L NP R+ CI IVEWKPF+ IL IFANC ALA P+PE DSN+ N LEK+E F++IFT E LKI+A+G ++HP AY+RNGWNLLDF+IVI+GL S +L ++++ GG DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TC+ + +D++ E P PC+ S N G QC ++G + C+ S W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND++G WPW+YFVSLII+GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E +G E GK + +S + + + ++ + E E Q + L R R RR + ++ V++ LVFLNT ++SEHY Q WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV I E ++++ + M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD S
Sbjct: 90 KSKKQGNSSNSRPARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGN-GRQCT---ANGTE--CR------SGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRN---------TSMPTSETESVNTENVSGEGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIV-LVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES 760 HSP 3 Score: 122.865 bits (307), Expect = 8.423e-27 Identity = 112/372 (30.11%), Postives = 168/372 (45.16%), Query Frame = 1
Query: 910 RPLNLAALTLSAQIASGGRKRTPARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR-----WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
RP ++ L + +IA P P+ A F L+ NP R C K++ F LIL I + ALAA P R + N+ L + F IFT E +LK+ FG +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y D +P C G + KD ++ W + +FDN AM+ +F T EGW ++Y DS G + IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 844 RPRRISELNMKEKIA---------------PIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPI--RSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCTDEAKSNPEEC---------------RGLFILYKDGDVDSPVVRERIWQNSDF---NFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1174 HSP 4 Score: 91.2781 bits (225), Expect = 3.776e-17 Identity = 57/203 (28.08%), Postives = 106/203 (52.22%), Query Frame = 1
Query: 4363 ITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
+ S F +++ VL+ LNT++++ + QP Q+ D N V +FT E L+K+ + G + YF +N FD +V G + I + + + I+ FR R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQA+L +F+ TGE W +M
Sbjct: 520 VKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSP-------LGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKR----STFDNFPQALLTVFQILTGEDWNAVM 711 HSP 5 Score: 87.8113 bits (216), Expect = 3.468e-16 Identity = 55/178 (30.90%), Postives = 92/178 (51.69%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPD----VKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKL 1557
+NP++ +V PFEY++ I N LA S N A++ + +VF +FT E VLK++AF P Y + WN D LIVI +I LS+ + R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+
Sbjct: 1191 KNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQH---YEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAF----KPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMF-GKV 1360 HSP 6 Score: 85.8853 bits (211), Expect = 1.573e-15 Identity = 79/286 (27.62%), Postives = 128/286 (44.76%), Query Frame = 1
Query: 3346 ASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPI-----------NNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGK------FQSCNDVSKNTHISC----RGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
A + F NN R+ C I F +L+ I + LA P D +S N L +Y F +FTVE LK+I YGL+ H A+ R+ N+LD ++V+ + S + ++ S ++ LR R LR + G+ + + +K++ ++ + L+ F ++A+IG++LF GK F + V++ C G+ N + +V I NFDN AMLT+F T EGW VLY D+ ++ +Y
Sbjct: 103 ARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGIT---NFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVY 385 HSP 7 Score: 85.5001 bits (210), Expect = 1.769e-15 Identity = 59/249 (23.69%), Postives = 112/249 (44.98%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVN----GTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-----------------------------GKITTENEKEMKE--INRN---NNFQTFPQAILVLFRSATGEAWQNIM 4971
++ +PF+ I + I N ++LA+ + ++ + F +FTVE LK+ A+G Y + WN+ DF+IV+ +I + + G N++ + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G+ T N E + + N NF F A+L +F+ T E W +++
Sbjct: 122 IVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVL 370 HSP 8 Score: 85.1149 bits (209), Expect = 2.393e-15 Identity = 67/252 (26.59%), Postives = 138/252 (54.76%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPP---LGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGI-------RSYGNLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ VL+ LNT L +HY QS + + N++F +FT+EM++K+ + + YF +N FD +VI SI+++ + + D + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D + +NF +F Q++L +F+ TGE W E+M + S N G+ S + +Y++ ++ ++++N+F+A+ +DN
Sbjct: 1201 VVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNF 1452
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1D (calcium voltage-gated channel subunit alpha1 D [Source:HGNC Symbol;Acc:HGNC:1391]) HSP 1 Score: 975.696 bits (2521), Expect = 0.000e+0 Identity = 542/902 (60.09%), Postives = 658/902 (72.95%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAE----RRTHSIFGTMMNVLQRVGSTRRDS 5985
RR+SE+ KEKI PIP S+FFI N R CH + NH F N++LV IM+SSA LAAEDP+ + S RN IL YFDY FT++FTVEI LK+ T+G H GAFCR+ N+LD+LVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF C D +K+ CRG +I Y + D+ V +R W N+ NFDNV +AM+ LF VSTFEGWP +LYK+IDS E+ IYN+R +SIF+I YII++AFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S PFEY++FVLIMLNT+ LA++ +Q + + MD LNMVFTGVFTVE +LK+ AF K YFSDAWN FD +IV+GS ID+ + + ++R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQMFGK+ ++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP +CD SD E Y CGSNFA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ ++Q NEELR VIKKIWK+TS K+LDQVVPPAG+D+VTVGKFYATFLIQ++FR++K+++ + G +++ ++L RT + I P + CD +D + + E +R ++ G +N V S RRDS
Sbjct: 870 RRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNR----ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAM---RDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYT-------------------------------------------CGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRT--------LHDIGPEIRRAISCDLQDDEPEETKREEEDDVFKRNGALLGNHVN---HVNSDRRDS 1709 HSP 2 Score: 713.375 bits (1840), Expect = 0.000e+0 Identity = 400/693 (57.72%), Postives = 496/693 (71.57%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSE------------GGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMMES-PVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
++ + S N RP RALFCL+L NP R+ CI IVEWKPF+ IL IFANC ALA P+PE DSN+ N LEK+E F++IFT E LKI+A+G ++HP AY+RNGWNLLDF+IVI+GL S +L ++++ GG DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TC+ + +D++ E P PC+ S N G QC ++G + C+ S W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND++G WPW+YFVSLII+GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E +G E GK + +S + + + ++ + E E Q + L R R RR + ++ V++ LVFLNT ++SEHY Q WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV I E ++++ + M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD S
Sbjct: 114 KSKKQGNSSNSRPARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGN-GRQCT---ANGTE--CR------SGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRN---------TSMPTSETESVNTENVSGEGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIV-LVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES 784 HSP 3 Score: 122.865 bits (307), Expect = 8.892e-27 Identity = 112/372 (30.11%), Postives = 168/372 (45.16%), Query Frame = 1
Query: 910 RPLNLAALTLSAQIASGGRKRTPARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR-----WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
RP ++ L + +IA P P+ A F L+ NP R C K++ F LIL I + ALAA P R + N+ L + F IFT E +LK+ FG +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y D +P C G + KD ++ W + +FDN AM+ +F T EGW ++Y DS G + IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 868 RPRRISELNMKEKIA---------------PIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPI--RSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCTDEAKSNPEEC---------------RGLFILYKDGDVDSPVVRERIWQNSDF---NFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1198 HSP 4 Score: 90.8929 bits (224), Expect = 4.222e-17 Identity = 57/203 (28.08%), Postives = 106/203 (52.22%), Query Frame = 1
Query: 4363 ITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
+ S F +++ VL+ LNT++++ + QP Q+ D N V +FT E L+K+ + G + YF +N FD +V G + I + + + I+ FR R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQA+L +F+ TGE W +M
Sbjct: 544 VKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSP-------LGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKR----STFDNFPQALLTVFQILTGEDWNAVM 735 HSP 5 Score: 87.8113 bits (216), Expect = 3.418e-16 Identity = 55/178 (30.90%), Postives = 92/178 (51.69%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPD----VKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKL 1557
+NP++ +V PFEY++ I N LA S N A++ + +VF +FT E VLK++AF P Y + WN D LIVI +I LS+ + R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+
Sbjct: 1215 KNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQH---YEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAF----KPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMF-GKV 1384 HSP 6 Score: 85.8853 bits (211), Expect = 1.563e-15 Identity = 79/286 (27.62%), Postives = 128/286 (44.76%), Query Frame = 1
Query: 3346 ASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPI-----------NNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGK------FQSCNDVSKNTHISC----RGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
A + F NN R+ C I F +L+ I + LA P D +S N L +Y F +FTVE LK+I YGL+ H A+ R+ N+LD ++V+ + S + ++ S ++ LR R LR + G+ + + +K++ ++ + L+ F ++A+IG++LF GK F + V++ C G+ N + +V I NFDN AMLT+F T EGW VLY D+ ++ +Y
Sbjct: 127 ARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGIT---NFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVY 409 HSP 7 Score: 85.5001 bits (210), Expect = 1.773e-15 Identity = 59/249 (23.69%), Postives = 112/249 (44.98%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVN----GTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-----------------------------GKITTENEKEMKE--INRN---NNFQTFPQAILVLFRSATGEAWQNIM 4971
++ +PF+ I + I N ++LA+ + ++ + F +FTVE LK+ A+G Y + WN+ DF+IV+ +I + + G N++ + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G+ T N E + + N NF F A+L +F+ T E W +++
Sbjct: 146 IVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVL 394 HSP 8 Score: 85.1149 bits (209), Expect = 2.419e-15 Identity = 67/252 (26.59%), Postives = 138/252 (54.76%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPP---LGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGI-------RSYGNLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ VL+ LNT L +HY QS + + N++F +FT+EM++K+ + + YF +N FD +VI SI+++ + + D + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D + +NF +F Q++L +F+ TGE W E+M + S N G+ S + +Y++ ++ ++++N+F+A+ +DN
Sbjct: 1225 VVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNF 1476
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Human
Match: CACNA1D (calcium voltage-gated channel subunit alpha1 D [Source:HGNC Symbol;Acc:HGNC:1391]) HSP 1 Score: 974.926 bits (2519), Expect = 0.000e+0 Identity = 542/902 (60.09%), Postives = 658/902 (72.95%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAE----RRTHSIFGTMMNVLQRVGSTRRDS 5985
RR+SE+ KEKI PIP S+FFI N R CH + NH F N++LV IM+SSA LAAEDP+ + S RN IL YFDY FT++FTVEI LK+ T+G H GAFCR+ N+LD+LVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF C D +K+ CRG +I Y + D+ V +R W N+ NFDNV +AM+ LF VSTFEGWP +LYK+IDS E+ IYN+R +SIF+I YII++AFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S PFEY++FVLIMLNT+ LA++ +Q + + MD LNMVFTGVFTVE +LK+ AF K YFSDAWN FD +IV+GS ID+ + + ++R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQMFGK+ ++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP +CD SD E Y CGSNFA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ ++Q NEELR VIKKIWK+TS K+LDQVVPPAG+D+VTVGKFYATFLIQ++FR++K+++ + G +++ ++L RT + I P + CD +D + + E +R ++ G +N V S RRDS
Sbjct: 846 RRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNR----ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAM---RDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYT-------------------------------------------CGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRT--------LHDIGPEIRRAISCDLQDDEPEETKREEEDDVFKRNGALLGNHVN---HVNSDRRDS 1685 HSP 2 Score: 706.057 bits (1821), Expect = 0.000e+0 Identity = 398/693 (57.43%), Postives = 494/693 (71.28%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSE------------GGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMMES-PVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
++ + S N RP RALFCL+L NP R+ CI IVEWKPF+ IL IFANC ALA P+PE DSN+ N LEK+E F++IFT E LKI+A+G ++HP AY+RNGWNLLDF+IVI+GL S +L ++++ GG DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TC+ + +D++ E P PC+ S N G QC ++G + C+ S W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND++G PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E +G E GK + +S + + + ++ + E E Q + L R R RR + ++ V++ LVFLNT ++SEHY Q WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV I E ++++ + M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD S
Sbjct: 90 KSKKQGNSSNSRPARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGN-GRQCT---ANGTE--CR------SGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRN---------TSMPTSETESVNTENVSGEGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIV-LVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES 760 HSP 3 Score: 122.865 bits (307), Expect = 9.382e-27 Identity = 112/372 (30.11%), Postives = 168/372 (45.16%), Query Frame = 1
Query: 910 RPLNLAALTLSAQIASGGRKRTPARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR-----WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
RP ++ L + +IA P P+ A F L+ NP R C K++ F LIL I + ALAA P R + N+ L + F IFT E +LK+ FG +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y D +P C G + KD ++ W + +FDN AM+ +F T EGW ++Y DS G + IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 844 RPRRISELNMKEKIA---------------PIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPI--RSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCTDEAKSNPEEC---------------RGLFILYKDGDVDSPVVRERIWQNSDF---NFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1174 HSP 4 Score: 90.8929 bits (224), Expect = 4.351e-17 Identity = 57/203 (28.08%), Postives = 106/203 (52.22%), Query Frame = 1
Query: 4363 ITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
+ S F +++ VL+ LNT++++ + QP Q+ D N V +FT E L+K+ + G + YF +N FD +V G + I + + + I+ FR R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQA+L +F+ TGE W +M
Sbjct: 520 VKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSP-------LGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKR----STFDNFPQALLTVFQILTGEDWNAVM 711 HSP 5 Score: 87.8113 bits (216), Expect = 4.168e-16 Identity = 55/178 (30.90%), Postives = 92/178 (51.69%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPD----VKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKL 1557
+NP++ +V PFEY++ I N LA S N A++ + +VF +FT E VLK++AF P Y + WN D LIVI +I LS+ + R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+
Sbjct: 1191 KNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQH---YEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAF----KPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMF-GKV 1360 HSP 6 Score: 87.0409 bits (214), Expect = 5.881e-16 Identity = 63/257 (24.51%), Postives = 117/257 (45.53%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVN----GTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-----------------------------GKITTENEKEMKE--INRN---NNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
++ +PF+ I + I N ++LA+ + ++ + F +FTVE LK+ A+G Y + WN+ DF+IV+ +I + + G N++ + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G+ T N E + + N NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 122 IVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDV-LYWMNDAM 377 HSP 7 Score: 85.1149 bits (209), Expect = 2.536e-15 Identity = 67/252 (26.59%), Postives = 138/252 (54.76%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPP---LGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGI-------RSYGNLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ VL+ LNT L +HY QS + + N++F +FT+EM++K+ + + YF +N FD +VI SI+++ + + D + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D + +NF +F Q++L +F+ TGE W E+M + S N G+ S + +Y++ ++ ++++N+F+A+ +DN
Sbjct: 1201 VVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNF 1452 HSP 8 Score: 83.9593 bits (206), Expect = 5.492e-15 Identity = 79/286 (27.62%), Postives = 127/286 (44.41%), Query Frame = 1
Query: 3346 ASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPI-----------NNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGK------FQSCNDVSKNTHISC----RGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
A + F NN R+ C I F +L+ I + LA P D +S N L +Y F +FTVE LK+I YGL+ H A+ R+ N+LD ++V+ + S + ++ S ++ LR R LR + G+ + + +K++ ++ + L+ F ++A+IG++LF GK F + V++ C G+ N + +V I NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 103 ARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGIT---NFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVY 385
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Celegans
Match: egl-19 (Voltage-dependent L-type calcium channel subunit alpha [Source:UniProtKB/TrEMBL;Acc:W6RY76]) HSP 1 Score: 1032.32 bits (2668), Expect = 0.000e+0 Identity = 589/1014 (58.09%), Postives = 707/1014 (69.72%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHC--LPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAG-NDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP--FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTL---APVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPL---TSKQPRVEYTMRDKLSLRSPPLDID 6303
RR+SEV A +KPIP ASS FI N FR FC+ + NH +F N VL CI+VSSAMLAAEDPL A S+RN ILNYFDY FTSVFTVEITLKVI +GLVFH G+FCR++ N+LD+LVV S+ S+ + DA+SVVKILRVLRVLRPLRAINRAKGLK VVQCV+VAVK+IGNIMLVTF+L+FMFA+IGVQLF G F CND+SK T CRG+YI+Y + D K KR W NN NFDNV +AM++LF VSTFEGWP +LY +IDS +ED I+N+R V++F+IA+IIVIAFFM+NIFVGFVIVTFQ EGE EY+NCELDKNQRKCIEFALKAKP RRYIP+ +YRVWW +TSR FEY+IF++I++NT+SLA K + +E +D N++FTGVF E +LK+ A KNY SD WNVFD ++V+GSFIDI Y +N N LISINFFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIV+LFFIYAVIGMQ FGK+ ++ I+RNNNF +FP AILVLFRSATGEAWQ+IML C D CD +SD K G N+S +CG+NFAYPYFISF+M+CSFL+INLFVAVIMDNFDYLTRDWSILGPHHL+EFVRLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV FNATLFALVRTNLKI T+G+ +D+ NE+LR IK+IWKRT + +LD+VVPPAG DDVTVGKFYATFLIQ++FRR+K+++ E KG+ +Q+ + + RT L IS L T DE + P H RR HS+F +++ L GS + G ST LP + P S + PV + AP+ + + SA P LP + D P T + + + R ++ R+ P+D D
Sbjct: 758 RRMSEVPAASTVKPIPKASSLFILSHTNSFRVFCNMVVNHSYFTNAVLFCILVSSAMLAAEDPLQANSTRNMILNYFDYFFTSVFTVEITLKVIVFGLVFHKGSFCRNAFNLLDILVVAVSLTSFVLRTDAMSVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIMLVTFMLQFMFAIIGVQLFKGTFFLCNDLSKMTEAECRGEYIHYEDGDPTKPVSKKRVWSNNDFNFDNVGDAMISLFVVSTFEGWPQLLYVAIDSNEEDKGPIHNSRQAVALFFIAFIIVIAFFMMNIFVGFVIVTFQNEGEREYENCELDKNQRKCIEFALKAKPHRRYIPRNRLQYRVWWFVTSRAFEYVIFLIIVMNTVSLACKHYPSSRGFEDFLDVFNLIFTGVFAFEAVLKIVALNPKNYISDRWNVFDLLVVVGSFIDITYGKLNPGGTN-----LISINFFRLFRVMRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAVIGMQFFGKVALDDS---TSIHRNNNFHSFPAAILVLFRSATGEAWQDIMLSCSDREDVRCDPMSDDYHKG---------------GLNES-------------------------RCGNNFAYPYFISFFMLCSFLVINLFVAVIMDNFDYLTRDWSILGPHHLEEFVRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRLACKRLVSMNMPLNSDGTVCFNATLFALVRTNLKIYTEGN-IDEANEQLRSAIKRIWKRTHKDLLDEVVPPAGKEDDVTVGKFYATFLIQDYFRRFKKRKEMEAKGVLPAQTPQAMALQAGLRTLHEIGPELKRAISGNLETDFNFDEPE----PQH----RRPHSLFNNLVHRLSGAGSKSPTEHERIEKG----STLLPFQPRSFSP---THSLAGAEGSPVPSQMHRGAPINQSINLPPVNGSARRLPALPPYANHIHDETDDGPRYRDTGDRAGYDQSSRMVVANRNLPVDPD 1707 HSP 2 Score: 502.286 bits (1292), Expect = 5.728e-145 Identity = 243/393 (61.83%), Postives = 297/393 (75.57%), Query Frame = 1
Query: 916 LNLAALTLSAQIASGGR--KRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY--SKNDVMMESPVPCSTSV-NKGYQC---DDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDI---SDDEEND 2061
L A S+Q A+ R +R P R + R +R+L CL+L NP RK CI IVEWKPFE+LILF I ANC ALA PYP +DS+ N+ LE IE VFIV+FT ECVLKI+A GF+ HP AYLRN WN+LDF+IV+IGL+ST+LSKMS G DVKALRAFRVLRPLRLVSG+PSLQVV+N+I+RAM+PL HIALL LFVI+IYAIIGLELF GKLHSTC + + + P PC T ++C D + G ++ C N + W GPN GIT+FDNFGLAMLTVFQC+++EGWT +MYW+ND+VG WPWIYFV+L+I+GSFFV+NLVLGVLSGEFSKEREKA+ RG +QK RE+ Q +ED++GYLDWI AEDI ++DE+ D
Sbjct: 32 LQAAVAASSSQDATKKRPAQRKPLRQTNVVERSERSLLCLSLNNPIRKLCISIVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVFTIECVLKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILSKMSIQGFDVKALRAFRVLRPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELFCGKLHSTCIDPATGQLAQKDPTPCGTDTEGSAFKCQPSDSLTNMGVRWECSSN----TTWPGPNNGITNFDNFGLAMLTVFQCVSLEGWTDVMYWVNDAVGREWPWIYFVTLVILGSFFVLNLVLGVLSGEFSKEREKARARGLFQKFREKQQLEEDLKGYLDWITQAEDIEPVNEDEQED 420 HSP 3 Score: 276.174 bits (705), Expect = 7.591e-74 Identity = 174/243 (71.60%), Postives = 205/243 (84.36%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
LVKSQ FYW+VI+LV LNT VLTSEHY QS WLD FQ AN+ FV+LF++EML+KMYSLG Y FNRFD FVVI SILE V++ D M PLGVSVLR ARLLR+FKVT+YW+SLRNLV SLL S++SI+SLL+LLFLFIVIF+LLGMQ+FGGKFNF+ ++ KPR+NFD+FVQ+LLTVFQILTGEDWN VMY GI S+G +G ++ C+YY++LFICGNYILLNVFLAIAVDNLAD S
Sbjct: 469 LVKSQTFYWLVILLVLLNTLVLTSEHYGQSEWLDHFQTMANLFFVILFSMEMLLKMYSLGFTTYTTSQFNRFDCFVVISSILEFVLVYFDLMKPLGVSVLRSARLLRIFKVTKYWTSLRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGGKFNFNPQQPKPRANFDTFVQALLTVFQILTGEDWNTVMYHGIESFGGVGTLGVIVCIYYIVLFICGNYILLNVFLAIAVDNLADADS 711 HSP 4 Score: 142.51 bits (358), Expect = 3.605e-33 Identity = 106/349 (30.37%), Postives = 169/349 (48.42%), Query Frame = 1
Query: 973 TPARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR---WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDS---------VGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
PA S + P P+ +LF L+ N FR FC +V F +LF I + LAA P + ++T N L + F +FT E LK++ FG + H G++ RN +NLLD L+V + L S VL ++ VK LR RVLRPLR ++ L+ V+ ++ A+ + +I L+ + ++AIIG++LF G T + ND+ + C Y D S+ WS + +FDN G AM+++F T EGW Q++Y DS ++F++ II+ +FF+MN+ +G + F E E+ + + K + +
Sbjct: 763 VPAAS-TVKPIPKASSLFILSHTNSFRVFCNMVVNHSYFTNAVLFCILVSSAMLAAEDPL--QANSTRNMILNYFDYFFTSVFTVEITLKVIVFGLVFHKGSFCRNAFNLLDILVVAVSLTSFVLR--TDAMSVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIMLVTFMLQFMFAIIGVQLFKG----TFFLCNDLSKMTEAEC-------------RGEYIHYEDGDPTKPVSKKRVWSNNDF---NFDNVGDAMISLFVVSTFEGWPQLLYVAIDSNEEDKGPIHNSRQAVALFFIAFIIVIAFFMMNIFVGFVIVTFQNEGEREYENCELDKNQRK 1086 HSP 5 Score: 95.1301 bits (235), Expect = 7.336e-19 Identity = 90/355 (25.35%), Postives = 156/355 (43.94%), Query Frame = 1
Query: 1069 VEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKAL---RAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWIND---------------------SVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKY---QKAREQMQFDEDVQG---YLDWIGAAEDIS 2043
V + FEY+I I N +LA YP S L+ L+F +F E VLKI+A ++P Y+ + WN+ D L+V+ I K++ GG ++ ++ R FRV+R ++L+S ++ ++ + M++ L ++ALL + + IYA+IG++ F GK+ + +D STS+++ ++FHS F A+L +F+ T E W IM +D G ++ + YF+S ++ SF V+NL + V+ F G + + R ++D D +G +LD + IS
Sbjct: 1114 VTSRAFEYVIFLIIVMNTVSLACKH-YPS--SRGFEDFLDVFNLIFTGVFAFEAVLKIVA----LNPKNYISDRWNVFDLLVVVGSFIDITYGKLNPGGTNLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAVIGMQFF-GKV-----ALDD---------STSIHRN---NNFHS-----------------------------FPAAILVLFRSATGEAWQDIMLSCSDREDVRCDPMSDDYHKGGLNESRCGNNFAYPYFISFFMLCSFLVINLFVAVIMDNFDYLTRDWSILGPHHLEEFVRLWSEYDPDAKGRIKHLDVVTLLRKIS 1414 HSP 6 Score: 90.1225 bits (222), Expect = 2.547e-17 Identity = 78/320 (24.38%), Postives = 144/320 (45.00%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLAL--KFDKQPQRYEQ-VMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-GKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNL---GFNDSMVIWPPHNFVKVKINKYIS--HYQDVA-----KCGSNFAYPYFISFYMICSFLIINLFVAVIMDNF 5265
++ +PFE++I +I N I+LA+ + Q Y+ +++ + VF VFT+E +LK+ A GF Y +AWN+ DFIIV+ + I ++ + R FRV+R ++L+S ++ +L +++ L ++ALL++ + IYA+IG+++F GK+ + ATG+ Q C D A Q N+ V R + N G N+ + + + + + +S + DV G + + YF++ ++ SF ++NL + V+ F
Sbjct: 84 IVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVFTIECVLKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILSKMSIQG--------FDVKALRAFRVLRPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELFCGKLHS-----------------------TCIDPATGQLAQKDPTPCGTDTEGSAFKCQPSDSLTNMGV-RWECSSNTTWPGPNNGITNFDNFGLAMLTVFQCVSLEGWTDVMYWVNDAVGREWPWIYFVTLVILGSFFVLNLVLGVLSGEF 371 HSP 7 Score: 89.3521 bits (220), Expect = 4.705e-17 Identity = 84/282 (29.79%), Postives = 134/282 (47.52%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESS--RNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAIS--XXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQS-----------------CNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWI---NNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
S NN RK C I F ++L I + LA P A+ S +N +L +Y+F VFT+E LK++ G +FH A+ R++ NILD ++V+ ++S ++ +I VK LR RVLRPLR ++ L+ V+ ++ A+ + +I L+ + ++A+IG++LF GK S C ++ + C+ N + N W N NFDN AMLT+F + EGW V+Y D+ ++ IY
Sbjct: 67 SLLCLSLNNPIRKLCISIVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVFTIECVLKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILSKMSIQGFDVKALRAFRVLRPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELFCGKLHSTCIDPATGQLAQKDPTPCGTDTEGSAFKCQPSDSLTNMGVRWECSSNT-TWPGPNNGITNFDNFGLAMLTVFQCVSLEGWTDVMYWVNDAVGREWPWIY 347 HSP 8 Score: 75.8702 bits (185), Expect = 5.080e-13 Identity = 66/256 (25.78%), Postives = 133/256 (51.95%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVM--IQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMY-----DGIRS--------YGNLGKSSM---LSCLYYVILFICGNYILLNVFLAIAVDNL 2991
V S+AF +V+ +++ +NT L +HY S + F + N+IF +F E ++K+ +L + Y +N FD VV+ S ++I + + ++ R R++R+ K+ +R L+ + + S +++ + +L+ L I++++GMQ FG D + R +NF SF ++L +F+ TGE W ++M + +R G L +S + Y++ F+ +++++N+F+A+ +DN
Sbjct: 1113 FVTSRAFEYVIFLIIVMNTVSLACKHYPSSRGFEDFLDVFNLIFTGVFAFEAVLKIVALNPKNYISDRWNVFDLLVVVGSFIDITYGKLNPGGTNLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAVIGMQFFGKVALDDSTSIHRNNNFHSFPAAILVLFRSATGEAWQDIMLSCSDREDVRCDPMSDDYHKGGLNESRCGNNFAYPYFISFFMLCSFLVINLFVAVIMDNF 1368 HSP 9 Score: 67.3958 bits (163), Expect = 1.981e-10 Identity = 56/206 (27.18%), Postives = 111/206 (53.88%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLH 4977
L+ S+ F +++ +L++LNT+ L + Q + + N+ F +F++E LLK+ + GF Y + +N FD +V+ S ++ + + + + + ++ R R++R+ K+ +R L+ + + S +++ + LL+ + I+A++GMQ+FG N ++ K NF TF QA+L +F+ TGE W +M H
Sbjct: 469 LVKSQTFYWLVILLVLLNTLVLTSEHYGQSEWLDHFQTMANLFFVILFSMEMLLKMYSLGFTTYTTSQFNRFDCFVVISSILEFVLVYFDLM-------KPLGVSVLRSARLLRIFKVTKYWTSLRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGGKFNFNPQQPKP---RANFDTFVQALLTVFQILTGEDWNTVMYH 664 HSP 10 Score: 56.9954 bits (136), Expect = 3.329e-7 Identity = 59/243 (24.28%), Postives = 108/243 (44.44%), Query Frame = 1
Query: 1198 LVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPW-----IYFVSLIIIGSFFVMNLVLGV 1908
L F+++F+ E +LK+ + GF Y + +N D +VI ++ VL P V LR+ R+LR ++ SL+ +++S++ ++ + + LL I+I+A++G+++F GK + + P P + +FD F A+LTVFQ +T E W +MY +S G IY++ L I G++ ++N+ L +
Sbjct: 510 LFFVILFSMEMLLKMYSLGFT----TYTTSQFNRFDCFVVISSILEFVLVYFDLMKPLGVSVLRSARLLRIFKVTKYWTSLRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGGKFNFNP--------QQPKPRA---------------------------------------NFDTFVQALLTVFQILTGEDWNTVMYHGIESFGGVGTLGVIVCIYYIVLFICGNYILLNVFLAI 701
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Celegans
Match: egl-19 (Voltage-dependent L-type calcium channel subunit alpha [Source:UniProtKB/TrEMBL;Acc:W6RY76]) HSP 1 Score: 1031.94 bits (2667), Expect = 0.000e+0 Identity = 567/910 (62.31%), Postives = 671/910 (73.74%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHC--LPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAG-NDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP--FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGS 6009
RR+SEV A +KPIP ASS FI N FR FC+ + NH +F N VL CI+VSSAMLAAEDPL A S+RN ILNYFDY FTSVFTVEITLKVI +GLVFH G+FCR++ N+LD+LVV S+ S+ + DA+SVVKILRVLRVLRPLRAINRAKGLK VVQCV+VAVK+IGNIMLVTF+L+FMFA+IGVQLF G F CND+SK T CRG+YI+Y + D K KR W NN NFDNV +AM++LF VSTFEGWP +LY +IDS +ED I+N+R V++F+IA+IIVIAFFM+NIFVGFVIVTFQ EGE EY+NCELDKNQRKCIEFALKAKP RRYIP+ +YRVWW +TSR FEY+IF++I++NT+SLA K + +E +D N++FTGVF E +LK+ A KNY SD WNVFD ++V+GSFIDI Y +N N LISINFFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIV+LFFIYAVIGMQ FGK+ ++ I+RNNNF +FP AILVLFRSATGEAWQ+IML C D CD +SD K G N+S +CG+NFAYPYFISF+M+CSFL+INLFVAVIMDNFDYLTRDWSILGPHHL+EFVRLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV FNATLFALVRTNLKI T+G+ +D+ NE+LR IK+IWKRT + +LD+VVPPAG DDVTVGKFYATFLIQ++FRR+K+++ E KG+ +Q+ + + RT L IS L T DE + P H RR HS+F +++ L GS + GS
Sbjct: 758 RRMSEVPAASTVKPIPKASSLFILSHTNSFRVFCNMVVNHSYFTNAVLFCILVSSAMLAAEDPLQANSTRNMILNYFDYFFTSVFTVEITLKVIVFGLVFHKGSFCRNAFNLLDILVVAVSLTSFVLRTDAMSVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIMLVTFMLQFMFAIIGVQLFKGTFFLCNDLSKMTEAECRGEYIHYEDGDPTKPVSKKRVWSNNDFNFDNVGDAMISLFVVSTFEGWPQLLYVAIDSNEEDKGPIHNSRQAVALFFIAFIIVIAFFMMNIFVGFVIVTFQNEGEREYENCELDKNQRKCIEFALKAKPHRRYIPRNRLQYRVWWFVTSRAFEYVIFLIIVMNTVSLACKHYPSSRGFEDFLDVFNLIFTGVFAFEAVLKIVALNPKNYISDRWNVFDLLVVVGSFIDITYGKLNPGGTN-----LISINFFRLFRVMRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAVIGMQFFGKVALDDS---TSIHRNNNFHSFPAAILVLFRSATGEAWQDIMLSCSDREDVRCDPMSDDYHKG---------------GLNES-------------------------RCGNNFAYPYFISFFMLCSFLVINLFVAVIMDNFDYLTRDWSILGPHHLEEFVRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRLACKRLVSMNMPLNSDGTVCFNATLFALVRTNLKIYTEGN-IDEANEQLRSAIKRIWKRTHKDLLDEVVPPAGKEDDVTVGKFYATFLIQDYFRRFKKRKEMEAKGVLPAQTPQAMALQAGLRTLHEIGPELKRAISGNLETDFNFDEPE----PQH----RRPHSLFNNLVHRLSGAGSKSPTEHERIEKGS 1610 HSP 2 Score: 502.671 bits (1293), Expect = 1.438e-145 Identity = 243/393 (61.83%), Postives = 297/393 (75.57%), Query Frame = 1
Query: 916 LNLAALTLSAQIASGGR--KRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY--SKNDVMMESPVPCSTSV-NKGYQC---DDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDI---SDDEEND 2061
L A S+Q A+ R +R P R + R +R+L CL+L NP RK CI IVEWKPFE+LILF I ANC ALA PYP +DS+ N+ LE IE VFIV+FT ECVLKI+A GF+ HP AYLRN WN+LDF+IV+IGL+ST+LSKMS G DVKALRAFRVLRPLRLVSG+PSLQVV+N+I+RAM+PL HIALL LFVI+IYAIIGLELF GKLHSTC + + + P PC T ++C D + G ++ C N + W GPN GIT+FDNFGLAMLTVFQC+++EGWT +MYW+ND+VG WPWIYFV+L+I+GSFFV+NLVLGVLSGEFSKEREKA+ RG +QK RE+ Q +ED++GYLDWI AEDI ++DE+ D
Sbjct: 32 LQAAVAASSSQDATKKRPAQRKPLRQTNVVERSERSLLCLSLNNPIRKLCISIVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVFTIECVLKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILSKMSIQGFDVKALRAFRVLRPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELFCGKLHSTCIDPATGQLAQKDPTPCGTDTEGSAFKCQPSDSLTNMGVRWECSSN----TTWPGPNNGITNFDNFGLAMLTVFQCVSLEGWTDVMYWVNDAVGREWPWIYFVTLVILGSFFVLNLVLGVLSGEFSKEREKARARGLFQKFREKQQLEEDLKGYLDWITQAEDIEPVNEDEQED 420 HSP 3 Score: 276.174 bits (705), Expect = 6.758e-74 Identity = 174/243 (71.60%), Postives = 205/243 (84.36%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
LVKSQ FYW+VI+LV LNT VLTSEHY QS WLD FQ AN+ FV+LF++EML+KMYSLG Y FNRFD FVVI SILE V++ D M PLGVSVLR ARLLR+FKVT+YW+SLRNLV SLL S++SI+SLL+LLFLFIVIF+LLGMQ+FGGKFNF+ ++ KPR+NFD+FVQ+LLTVFQILTGEDWN VMY GI S+G +G ++ C+YY++LFICGNYILLNVFLAIAVDNLAD S
Sbjct: 469 LVKSQTFYWLVILLVLLNTLVLTSEHYGQSEWLDHFQTMANLFFVILFSMEMLLKMYSLGFTTYTTSQFNRFDCFVVISSILEFVLVYFDLMKPLGVSVLRSARLLRIFKVTKYWTSLRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGGKFNFNPQQPKPRANFDTFVQALLTVFQILTGEDWNTVMYHGIESFGGVGTLGVIVCIYYIVLFICGNYILLNVFLAIAVDNLADADS 711 HSP 4 Score: 142.51 bits (358), Expect = 3.534e-33 Identity = 106/349 (30.37%), Postives = 169/349 (48.42%), Query Frame = 1
Query: 973 TPARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR---WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDS---------VGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
PA S + P P+ +LF L+ N FR FC +V F +LF I + LAA P + ++T N L + F +FT E LK++ FG + H G++ RN +NLLD L+V + L S VL ++ VK LR RVLRPLR ++ L+ V+ ++ A+ + +I L+ + ++AIIG++LF G T + ND+ + C Y D S+ WS + +FDN G AM+++F T EGW Q++Y DS ++F++ II+ +FF+MN+ +G + F E E+ + + K + +
Sbjct: 763 VPAAS-TVKPIPKASSLFILSHTNSFRVFCNMVVNHSYFTNAVLFCILVSSAMLAAEDPL--QANSTRNMILNYFDYFFTSVFTVEITLKVIVFGLVFHKGSFCRNAFNLLDILVVAVSLTSFVLR--TDAMSVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIMLVTFMLQFMFAIIGVQLFKG----TFFLCNDLSKMTEAEC-------------RGEYIHYEDGDPTKPVSKKRVWSNNDF---NFDNVGDAMISLFVVSTFEGWPQLLYVAIDSNEEDKGPIHNSRQAVALFFIAFIIVIAFFMMNIFVGFVIVTFQNEGEREYENCELDKNQRK 1086 HSP 5 Score: 95.1301 bits (235), Expect = 8.336e-19 Identity = 89/352 (25.28%), Postives = 155/352 (44.03%), Query Frame = 1
Query: 1078 KPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKAL---RAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWIND---------------------SVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKY---QKAREQMQFDEDVQG---YLDWIGAAEDIS 2043
+ FEY+I I N +LA YP S L+ L+F +F E VLKI+A ++P Y+ + WN+ D L+V+ I K++ GG ++ ++ R FRV+R ++L+S ++ ++ + M++ L ++ALL + + IYA+IG++ F GK+ + +D STS+++ ++FHS F A+L +F+ T E W IM +D G ++ + YF+S ++ SF V+NL + V+ F G + + R ++D D +G +LD + IS
Sbjct: 1117 RAFEYVIFLIIVMNTVSLACKH-YPS--SRGFEDFLDVFNLIFTGVFAFEAVLKIVA----LNPKNYISDRWNVFDLLVVVGSFIDITYGKLNPGGTNLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAVIGMQFF-GKV-----ALDD---------STSIHRN---NNFHS-----------------------------FPAAILVLFRSATGEAWQDIMLSCSDREDVRCDPMSDDYHKGGLNESRCGNNFAYPYFISFFMLCSFLVINLFVAVIMDNFDYLTRDWSILGPHHLEEFVRLWSEYDPDAKGRIKHLDVVTLLRKIS 1414 HSP 6 Score: 89.3521 bits (220), Expect = 5.048e-17 Identity = 78/320 (24.38%), Postives = 144/320 (45.00%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLAL--KFDKQPQRYEQ-VMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-GKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNL---GFNDSMVIWPPHNFVKVKINKYIS--HYQDVA-----KCGSNFAYPYFISFYMICSFLIINLFVAVIMDNF 5265
++ +PFE++I +I N I+LA+ + Q Y+ +++ + VF VFT+E +LK+ A GF Y +AWN+ DFIIV+ + I ++ + R FRV+R ++L+S ++ +L +++ L ++ALL++ + IYA+IG+++F GK+ + ATG+ Q C D A Q N+ V R + N G N+ + + + + + +S + DV G + + YF++ ++ SF ++NL + V+ F
Sbjct: 84 IVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVFTIECVLKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILSKMSIQG--------FDVKALRAFRVLRPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELFCGKLHS-----------------------TCIDPATGQLAQKDPTPCGTDTEGSAFKCQPSDSLTNMGV-RWECSSNTTWPGPNNGITNFDNFGLAMLTVFQCVSLEGWTDVMYWVNDAVGREWPWIYFVTLVILGSFFVLNLVLGVLSGEF 371 HSP 7 Score: 88.9669 bits (219), Expect = 5.972e-17 Identity = 75/282 (26.60%), Postives = 127/282 (45.04%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESS--RNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXX--XXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQS-----------------CNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWI---NNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
S NN RK C I F ++L I + LA P A+ S +N +L +Y+F VFT+E LK++ G +FH A+ R++ NILD ++V+ ++S ++ +I + + LR ++ L+ V+ ++ A+ + +I L+ + ++A+IG++LF GK S C ++ + C+ N + N W N NFDN AMLT+F + EGW V+Y D+ ++ IY
Sbjct: 67 SLLCLSLNNPIRKLCISIVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVFTIECVLKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILSKMSIQGFDVKALRAFRVLRPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELFCGKLHSTCIDPATGQLAQKDPTPCGTDTEGSAFKCQPSDSLTNMGVRWECSSNT-TWPGPNNGITNFDNFGLAMLTVFQCVSLEGWTDVMYWVNDAVGREWPWIY 347 HSP 8 Score: 75.8702 bits (185), Expect = 6.252e-13 Identity = 66/256 (25.78%), Postives = 133/256 (51.95%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVM--IQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMY-----DGIRS--------YGNLGKSSM---LSCLYYVILFICGNYILLNVFLAIAVDNL 2991
V S+AF +V+ +++ +NT L +HY S + F + N+IF +F E ++K+ +L + Y +N FD VV+ S ++I + + ++ R R++R+ K+ +R L+ + + S +++ + +L+ L I++++GMQ FG D + R +NF SF ++L +F+ TGE W ++M + +R G L +S + Y++ F+ +++++N+F+A+ +DN
Sbjct: 1113 FVTSRAFEYVIFLIIVMNTVSLACKHYPSSRGFEDFLDVFNLIFTGVFAFEAVLKIVALNPKNYISDRWNVFDLLVVVGSFIDITYGKLNPGGTNLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAVIGMQFFGKVALDDSTSIHRNNNFHSFPAAILVLFRSATGEAWQDIMLSCSDREDVRCDPMSDDYHKGGLNESRCGNNFAYPYFISFFMLCSFLVINLFVAVIMDNF 1368 HSP 9 Score: 67.0106 bits (162), Expect = 2.442e-10 Identity = 56/206 (27.18%), Postives = 111/206 (53.88%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLH 4977
L+ S+ F +++ +L++LNT+ L + Q + + N+ F +F++E LLK+ + GF Y + +N FD +V+ S ++ + + + + + ++ R R++R+ K+ +R L+ + + S +++ + LL+ + I+A++GMQ+FG N ++ K NF TF QA+L +F+ TGE W +M H
Sbjct: 469 LVKSQTFYWLVILLVLLNTLVLTSEHYGQSEWLDHFQTMANLFFVILFSMEMLLKMYSLGFTTYTTSQFNRFDCFVVISSILEFVLVYFDLM-------KPLGVSVLRSARLLRIFKVTKYWTSLRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGGKFNFNPQQPKP---RANFDTFVQALLTVFQILTGEDWNTVMYH 664 HSP 10 Score: 56.6102 bits (135), Expect = 4.216e-7 Identity = 59/243 (24.28%), Postives = 108/243 (44.44%), Query Frame = 1
Query: 1198 LVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPW-----IYFVSLIIIGSFFVMNLVLGV 1908
L F+++F+ E +LK+ + GF Y + +N D +VI ++ VL P V LR+ R+LR ++ SL+ +++S++ ++ + + LL I+I+A++G+++F GK + + P P + +FD F A+LTVFQ +T E W +MY +S G IY++ L I G++ ++N+ L +
Sbjct: 510 LFFVILFSMEMLLKMYSLGFT----TYTTSQFNRFDCFVVISSILEFVLVYFDLMKPLGVSVLRSARLLRIFKVTKYWTSLRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGGKFNFNP--------QQPKPRA---------------------------------------NFDTFVQALLTVFQILTGEDWNTVMYHGIESFGGVGTLGVIVCIYYIVLFICGNYILLNVFLAI 701
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Celegans
Match: unc-2 (High voltage activated calcium channel alpha-1 subunit [Source:UniProtKB/TrEMBL;Acc:Q86G45]) HSP 1 Score: 647.506 bits (1669), Expect = 0.000e+0 Identity = 367/813 (45.14%), Postives = 497/813 (61.13%), Query Frame = 1
Query: 3331 KPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXX------XXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQY-IYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIP--KQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDG-STVDQLNEELRVVIKKIWKRTSQK-MLDQVVPPAGN---DDVTVGKFYATFLIQEWFRRWK 5727
KP+ SS F P N FR H I +F +V+ I +SS LAAEDP+D E+ RN++L Y DY FT VF E+ LK+I G++ H G++CR NILD +VV ++ ++ S K L ++ LR LR + K +KR+ + V ++K++ NI++V FL +F+FAVI VQLFNGKF C D ++ +C GQ+ +Y N+ D +V +REW P N+DN NAMLTLF V+T EGWPG+ S+D+ ED R V++FY+ + IV FF +NIFV +I+TFQ++GE E +LDKNQ++CI+FAL A+P ++P K S +YR+W L+TS PFEY I +I NT+ L +K+ P YE+++ N T VFTVE +LK+ AFG +NYF D WN FDF+ V+GS D + G +S+ F RLFR RL++LL +G IR LLWTFV+SF+ALPYV LLI MLFFIYA++GMQ+FG I EINR+NNFQ+F A+++LFR ATGE WQ+IM+ + C +AG+ N ++ CGSN +Y YF SF + SFL++NLFVAVIMDNFDYLTRD SILGPHHLDEF+R+W++YDP A GRI + ++ +LR + PP+GFGK CP+R A L+RMNMP+ DGTV F TLFAL+R +L IK +D+ +EELR+ +KKIW ++K M+D VVPP +TVGK YA LI E +R K
Sbjct: 970 KPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFFCTDKNRKFANTCHGQFFVYDNQNDPPRV--EQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMDTTFEDQGPSPFFRVEVALFYVMFFIVFPFFFVNIFVALIIITFQEQGEAELSEGDLDKNQKQCIDFALNARPRSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGG--------HFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWL---NAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDC-------------------ARAGSAEIN----------------------FEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFIRVWADYDPAATGRIHYSEMYEMLRIMAPPVGFGKKCPYRLAYKHLIRMNMPVAEDGTVHFTTTLFALIRESLSIKMRPVEEMDEADEELRLTLKKIWPLKAKKNMVDLVVPPNHELCFQKLTVGKIYAGLLILENYRARK 1728 HSP 2 Score: 505.368 bits (1300), Expect = 9.128e-145 Identity = 315/705 (44.68%), Postives = 442/705 (62.70%), Query Frame = 1
Query: 964 RKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLIS-------TVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKN---DVMMESPVPCS--TSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDI------SDDEEN----DGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGA----HHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADT 3000
RK T + + + +LF N R+ I+EW PFEY IL TI NC L+ P+ D ++ LE+ E F+ IF ECVLK++AFGF +H G+YLR+GWN++DF++V+ G+++ T + D++ LRA RVLRPL+LVSG+PSLQVV+ SI+ AM PL I LL LF III+AIIGLE +SG HS CY++ + + E P+PC+ TS Y CD ++ + +W GPN GITSFDN G AM+TVFQCITMEGWT +MY+ NDS+G ++ W YF+ LI++GSFF++NLVLGVLSGEF+KERE+ + R ++ K R Q Q + ++ GYL+WI AE++ + +EE + + + K +S+E +D ++ + + + G +++++ C + + ++ R R +VK+Q FYW VI LVFLNT + SEHY Q W F A +F+ +F +EML+K++++G R YF FNRFD V++ S E++ + G+SV+R RLLR+FK+T YW SLRNLV SL+ SM+SI+SLL LLFLFI+IF+LLGMQLFGG+FNF P ++FD+F +L+TVFQILTGEDWNEVMY I S G + +Y+++L + GNY LLNVFLAIAVDNLA+
Sbjct: 214 RKTTLSSNAPVKEKGPSSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQ-----------KWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAYFIPLIVLGSFFMLNLVLGVLSGEFAKERERVENRREFLKLRRQQQIERELNGYLEWILTAEEVILKEDRTTEEEKAAIMEARRRAANKKLKQASKQQSTETEEDFEEDEDEMEEEYVDEGGTVEDEFAERKKRGCCHSVGK-----FIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYG-GSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNF-PTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLANA 900 HSP 3 Score: 122.865 bits (307), Expect = 3.139e-27 Identity = 87/280 (31.07%), Postives = 138/280 (49.29%), Query Frame = 1
Query: 994 GNPRPQ---RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPD-----VKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSF--DNFGLAMLTVFQCITMEGWTQI 1803
G P+P ++F L+ NPFR IV K FE +++ I + +LAA P E N N L+ ++ F +F E +LK++ G ++HPG+Y R+ WN+LD ++V L + + +EG +K+LR RVLRPL+ + +P L+ V + ++ ++ +F+I ++ I+A+I ++LF+GK C KN + C H F Y DN+N+ R + F DN AMLT+F T EGW I
Sbjct: 967 GGPKPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEE--NPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAG-TEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFF-FCTDKNRKFANT---C-------------HGQFFVY---DNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGI 1223 HSP 4 Score: 102.449 bits (254), Expect = 5.933e-21 Identity = 62/213 (29.11%), Postives = 114/213 (53.52%), Query Frame = 1
Query: 4333 QSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
+ R ++ ++ ++ F + + L+ LNT +A + QPQ + + Y VF G+F VE LLKL A G + YF+ +N FD ++++GS ++I+ V G + I+ R R++R+ KL S +R L+ + + S +++ + L+ + I+A++GMQ+FG ++ +F TFP A++ +F+ TGE W +M
Sbjct: 654 KQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGS--------FGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFG-----GRFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVM 853 HSP 5 Score: 87.4261 bits (215), Expect = 2.066e-16 Identity = 85/367 (23.16%), Postives = 152/367 (41.42%), Query Frame = 1
Query: 997 NPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAA---NTP-YPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIM------------------YWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAA 2031
N RP R+LF +N + ++V PFEY I+ I N L N P + E N+AL +FT E +LKILAFG Y R+GWN DF+ V+ + ++++ + LR FR R +RL+ ++++++ + +++ L ++ LL + IYAI+G+++F ++ + + +T +N+ +F +F A++ +F+C T EGW IM + + G + + YF S + + SF ++NL + V+ F + G + DE ++ + D+ AA
Sbjct: 1298 NARP-RSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTAL-------TAVFTVESILKILAFGV----RNYFRDGWNRFDFVTVVGSITDALVTEFGGHFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVF-----------GNIWLNA----ATEINRH--------------------------------NNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPH-------HLDEFIRVWADYDPAA 1598 HSP 6 Score: 80.4925 bits (197), Expect = 2.520e-14 Identity = 73/309 (23.62%), Postives = 138/309 (44.66%), Query Frame = 1
Query: 1066 IVEWKPFEYLILFTIFAN-CCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMG-ITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVG----MSWPW-IYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKA 1971
+V+ + F + ++ +F N CC + + P+ ++ + A E VF+ IF E +LK+ A G Y + +N D ++++ + +++ G + +RA R+LR +L S SL+ ++ S+M +M + + L I+I+A++G++LF G R++ P M T FD F +A++TVFQ +T E W ++MY +S G WP+ IYF+ L++ G++ ++N+ L + + +E +KA
Sbjct: 663 MVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYA----EFVFLGIFVVEMLLKLFAMG----SRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGG--------------------------------------------------RFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLANAQELTAAEEADEKA 913 HSP 7 Score: 72.4034 bits (176), Expect = 7.295e-12 Identity = 76/281 (27.05%), Postives = 129/281 (45.91%), Query Frame = 1
Query: 3349 SSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAED--PLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLK--RXXXXXXXXXKSIGNIM-------LVTFLLEFMFAVIGVQLFNGKFQSC--NDVSKNTHISCRGQYIYYNEADIA------KVFVNKREWIN---NPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
SS FIF +N R+ I F +L+ I+ + +L+ E P + + + + L + F +F +E LKVI +G H G++ RS NI+D +VV++ +++ + A LR LRA+ + LK + + V +KSI M L+ +FA+IG++ ++G F S N+ + ++S R + + K ++WI +FDN+ AM+T+F T EGW V+Y + DS Y+ Y
Sbjct: 230 SSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAY 510 HSP 8 Score: 68.1662 bits (165), Expect = 1.438e-10 Identity = 62/251 (24.70%), Postives = 130/251 (51.79%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKF-NFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYG---------NLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
LV S F + ++ ++ NT +L ++Y ++ + N +FT+E ++K+ + G+R YF +NRFDF V+ SI + ++ + + + LR R R+ ++ + ++R L+ + + S K++ + +L+ + I++++GMQ+FG + N + +NF SF +++ +F+ TGE W ++M ++ N K S +S Y+ ++++LN+F+A+ +DN
Sbjct: 1320 LVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGGH-FVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNF 1569 HSP 9 Score: 63.5438 bits (153), Expect = 3.674e-9 Identity = 55/246 (22.36%), Postives = 107/246 (43.50%), Query Frame = 1
Query: 4375 PFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMV---FTGVFTVEFLLKLAAFGFK----NYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF------------GKITTENEKEMKEINRNN--------------------------NFQTFPQAILVLFRSATGEAWQNIMLH 4977
PFEY I + I+ N + L+++ + + ++L F G+F +E +LK+ AFGF +Y WN+ DFI+V+ + ++ N D + + R RV+R +KL+S ++ +L + + + L + LL++ I+A+IG++ + G+I +E+ M N+ + +F A++ +F+ T E W +M +
Sbjct: 253 PFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDS-VDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYY 497
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Celegans
Match: unc-2 (High voltage activated calcium channel alpha-1 subunit [Source:UniProtKB/TrEMBL;Acc:Q86G45]) HSP 1 Score: 647.506 bits (1669), Expect = 0.000e+0 Identity = 375/813 (46.13%), Postives = 503/813 (61.87%), Query Frame = 1
Query: 3331 KPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDA------ISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQY-IYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIP--KQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDG-STVDQLNEELRVVIKKIWKRTSQK-MLDQVVPPAGN---DDVTVGKFYATFLIQEWFRRWK 5727
KP+ SS F P N FR H I +F +V+ I +SS LAAEDP+D E+ RN++L Y DY FT VF E+ LK+I G++ H G++CR NILD +VV ++ ++ ++ +K LRVLRVLRPL+ I R LK V CVV ++K++ NI++V FL +F+FAVI VQLFNGKF C D ++ +C GQ+ +Y N+ D +V +REW P N+DN NAMLTLF V+T EGWPG+ S+D+ ED R V++FY+ + IV FF +NIFV +I+TFQ++GE E +LDKNQ++CI+FAL A+P ++P K S +YR+W L+TS PFEY I +I NT+ L +K+ P YE+++ N T VFTVE +LK+ AFG +NYF D WN FDF+ V+GS D + G +S+ F RLFR RL++LL +G IR LLWTFV+SF+ALPYV LLI MLFFIYA++GMQ+FG I EINR+NNFQ+F A+++LFR ATGE WQ+IM+ + C +AG+ N ++ CGSN +Y YF SF + SFL++NLFVAVIMDNFDYLTRD SILGPHHLDEF+R+W++YDP A GRI + ++ +LR + PP+GFGK CP+R A L+RMNMP+ DGTV F TLFAL+R +L IK +D+ +EELR+ +KKIW ++K M+D VVPP +TVGK YA LI E +R K
Sbjct: 918 KPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFFCTDKNRKFANTCHGQFFVYDNQNDPPRV--EQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMDTTFEDQGPSPFFRVEVALFYVMFFIVFPFFFVNIFVALIIITFQEQGEAELSEGDLDKNQKQCIDFALNARPRSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGG--------HFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWL---NAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDC-------------------ARAGSAEIN----------------------FEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFIRVWADYDPAATGRIHYSEMYEMLRIMAPPVGFGKKCPYRLAYKHLIRMNMPVAEDGTVHFTTTLFALIRESLSIKMRPVEEMDEADEELRLTLKKIWPLKAKKNMVDLVVPPNHELCFQKLTVGKIYAGLLILENYRARK 1676 HSP 2 Score: 505.368 bits (1300), Expect = 6.506e-145 Identity = 315/705 (44.68%), Postives = 442/705 (62.70%), Query Frame = 1
Query: 964 RKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLIS-------TVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKN---DVMMESPVPCS--TSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDI------SDDEEN----DGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGA----HHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADT 3000
RK T + + + +LF N R+ I+EW PFEY IL TI NC L+ P+ D ++ LE+ E F+ IF ECVLK++AFGF +H G+YLR+GWN++DF++V+ G+++ T + D++ LRA RVLRPL+LVSG+PSLQVV+ SI+ AM PL I LL LF III+AIIGLE +SG HS CY++ + + E P+PC+ TS Y CD ++ + +W GPN GITSFDN G AM+TVFQCITMEGWT +MY+ NDS+G ++ W YF+ LI++GSFF++NLVLGVLSGEF+KERE+ + R ++ K R Q Q + ++ GYL+WI AE++ + +EE + + + K +S+E +D ++ + + + G +++++ C + + ++ R R +VK+Q FYW VI LVFLNT + SEHY Q W F A +F+ +F +EML+K++++G R YF FNRFD V++ S E++ + G+SV+R RLLR+FK+T YW SLRNLV SL+ SM+SI+SLL LLFLFI+IF+LLGMQLFGG+FNF P ++FD+F +L+TVFQILTGEDWNEVMY I S G + +Y+++L + GNY LLNVFLAIAVDNLA+
Sbjct: 162 RKTTLSSNAPVKEKGPSSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQ-----------KWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAYFIPLIVLGSFFMLNLVLGVLSGEFAKERERVENRREFLKLRRQQQIERELNGYLEWILTAEEVILKEDRTTEEEKAAIMEARRRAANKKLKQASKQQSTETEEDFEEDEDEMEEEYVDEGGTVEDEFAERKKRGCCHSVGK-----FIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYG-GSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNF-PTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLANA 848 HSP 3 Score: 122.865 bits (307), Expect = 3.531e-27 Identity = 87/280 (31.07%), Postives = 138/280 (49.29%), Query Frame = 1
Query: 994 GNPRPQ---RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPD-----VKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSF--DNFGLAMLTVFQCITMEGWTQI 1803
G P+P ++F L+ NPFR IV K FE +++ I + +LAA P E N N L+ ++ F +F E +LK++ G ++HPG+Y R+ WN+LD ++V L + + +EG +K+LR RVLRPL+ + +P L+ V + ++ ++ +F+I ++ I+A+I ++LF+GK C KN + C H F Y DN+N+ R + F DN AMLT+F T EGW I
Sbjct: 915 GGPKPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEE--NPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAG-TEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFF-FCTDKNRKFANT---C-------------HGQFFVY---DNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGI 1171 HSP 4 Score: 102.064 bits (253), Expect = 6.358e-21 Identity = 68/233 (29.18%), Postives = 123/233 (52.79%), Query Frame = 1
Query: 4288 EFALKAK-----PVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
EFA + K V ++I + + R+ ++ ++ F + + L+ LNT +A + QPQ + + Y VF G+F VE LLKL A G + YF+ +N FD ++++GS ++I+ V G + I+ R R++R+ KL S +R L+ + + S +++ + L+ + I+A++GMQ+FG ++ +F TFP A++ +F+ TGE W +M
Sbjct: 584 EFAERKKRGCCHSVGKFIKQLRIQIRI--MVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGS--------FGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFG-----GRFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVM 801 HSP 5 Score: 87.0409 bits (214), Expect = 2.370e-16 Identity = 85/367 (23.16%), Postives = 152/367 (41.42%), Query Frame = 1
Query: 997 NPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAA---NTP-YPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIM------------------YWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAA 2031
N RP R+LF +N + ++V PFEY I+ I N L N P + E N+AL +FT E +LKILAFG Y R+GWN DF+ V+ + ++++ + LR FR R +RL+ ++++++ + +++ L ++ LL + IYAI+G+++F ++ + + +T +N+ +F +F A++ +F+C T EGW IM + + G + + YF S + + SF ++NL + V+ F + G + DE ++ + D+ AA
Sbjct: 1246 NARP-RSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTAL-------TAVFTVESILKILAFGV----RNYFRDGWNRFDFVTVVGSITDALVTEFGGHFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVF-----------GNIWLNA----ATEINRH--------------------------------NNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPH-------HLDEFIRVWADYDPAA 1546 HSP 6 Score: 80.1073 bits (196), Expect = 2.728e-14 Identity = 73/309 (23.62%), Postives = 138/309 (44.66%), Query Frame = 1
Query: 1066 IVEWKPFEYLILFTIFAN-CCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMG-ITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVG----MSWPW-IYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKA 1971
+V+ + F + ++ +F N CC + + P+ ++ + A E VF+ IF E +LK+ A G Y + +N D ++++ + +++ G + +RA R+LR +L S SL+ ++ S+M +M + + L I+I+A++G++LF G R++ P M T FD F +A++TVFQ +T E W ++MY +S G WP+ IYF+ L++ G++ ++N+ L + + +E +KA
Sbjct: 611 MVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYA----EFVFLGIFVVEMLLKLFAMG----SRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGG--------------------------------------------------RFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLANAQELTAAEEADEKA 861 HSP 7 Score: 72.4034 bits (176), Expect = 7.026e-12 Identity = 76/281 (27.05%), Postives = 129/281 (45.91%), Query Frame = 1
Query: 3349 SSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAED--PLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLK--RXXXXXXXXXKSIGNIM-------LVTFLLEFMFAVIGVQLFNGKFQSC--NDVSKNTHISCRGQYIYYNEADIA------KVFVNKREWIN---NPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
SS FIF +N R+ I F +L+ I+ + +L+ E P + + + + L + F +F +E LKVI +G H G++ RS NI+D +VV++ +++ + A LR LRA+ + LK + + V +KSI M L+ +FA+IG++ ++G F S N+ + ++S R + + K ++WI +FDN+ AM+T+F T EGW V+Y + DS Y+ Y
Sbjct: 178 SSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAY 458 HSP 8 Score: 68.1662 bits (165), Expect = 1.242e-10 Identity = 62/251 (24.70%), Postives = 130/251 (51.79%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKF-NFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYG---------NLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
LV S F + ++ ++ NT +L ++Y ++ + N +FT+E ++K+ + G+R YF +NRFDF V+ SI + ++ + + + LR R R+ ++ + ++R L+ + + S K++ + +L+ + I++++GMQ+FG + N + +NF SF +++ +F+ TGE W ++M ++ N K S +S Y+ ++++LN+F+A+ +DN
Sbjct: 1268 LVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGGH-FVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNF 1517 HSP 9 Score: 63.1586 bits (152), Expect = 4.259e-9 Identity = 55/246 (22.36%), Postives = 107/246 (43.50%), Query Frame = 1
Query: 4375 PFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMV---FTGVFTVEFLLKLAAFGFK----NYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF------------GKITTENEKEMKEINRNN--------------------------NFQTFPQAILVLFRSATGEAWQNIMLH 4977
PFEY I + I+ N + L+++ + + ++L F G+F +E +LK+ AFGF +Y WN+ DFI+V+ + ++ N D + + R RV+R +KL+S ++ +L + + + L + LL++ I+A+IG++ + G+I +E+ M N+ + +F A++ +F+ T E W +M +
Sbjct: 201 PFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDS-VDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYY 445
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Celegans
Match: unc-2 (High voltage activated calcium channel alpha-1 subunit [Source:UniProtKB/TrEMBL;Acc:Q86G45]) HSP 1 Score: 647.506 bits (1669), Expect = 0.000e+0 Identity = 375/813 (46.13%), Postives = 503/813 (61.87%), Query Frame = 1
Query: 3331 KPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDA------ISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQY-IYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIP--KQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDG-STVDQLNEELRVVIKKIWKRTSQK-MLDQVVPPAGN---DDVTVGKFYATFLIQEWFRRWK 5727
KP+ SS F P N FR H I +F +V+ I +SS LAAEDP+D E+ RN++L Y DY FT VF E+ LK+I G++ H G++CR NILD +VV ++ ++ ++ +K LRVLRVLRPL+ I R LK V CVV ++K++ NI++V FL +F+FAVI VQLFNGKF C D ++ +C GQ+ +Y N+ D +V +REW P N+DN NAMLTLF V+T EGWPG+ S+D+ ED R V++FY+ + IV FF +NIFV +I+TFQ++GE E +LDKNQ++CI+FAL A+P ++P K S +YR+W L+TS PFEY I +I NT+ L +K+ P YE+++ N T VFTVE +LK+ AFG +NYF D WN FDF+ V+GS D + G +S+ F RLFR RL++LL +G IR LLWTFV+SF+ALPYV LLI MLFFIYA++GMQ+FG I EINR+NNFQ+F A+++LFR ATGE WQ+IM+ + C +AG+ N ++ CGSN +Y YF SF + SFL++NLFVAVIMDNFDYLTRD SILGPHHLDEF+R+W++YDP A GRI + ++ +LR + PP+GFGK CP+R A L+RMNMP+ DGTV F TLFAL+R +L IK +D+ +EELR+ +KKIW ++K M+D VVPP +TVGK YA LI E +R K
Sbjct: 926 KPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFFCTDKNRKFANTCHGQFFVYDNQNDPPRV--EQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMDTTFEDQGPSPFFRVEVALFYVMFFIVFPFFFVNIFVALIIITFQEQGEAELSEGDLDKNQKQCIDFALNARPRSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGG--------HFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWL---NAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDC-------------------ARAGSAEIN----------------------FEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFIRVWADYDPAATGRIHYSEMYEMLRIMAPPVGFGKKCPYRLAYKHLIRMNMPVAEDGTVHFTTTLFALIRESLSIKMRPVEEMDEADEELRLTLKKIWPLKAKKNMVDLVVPPNHELCFQKLTVGKIYAGLLILENYRARK 1684 HSP 2 Score: 504.982 bits (1299), Expect = 9.059e-145 Identity = 315/705 (44.68%), Postives = 442/705 (62.70%), Query Frame = 1
Query: 964 RKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLIS-------TVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKN---DVMMESPVPCS--TSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDI------SDDEEN----DGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGA----HHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADT 3000
RK T + + + +LF N R+ I+EW PFEY IL TI NC L+ P+ D ++ LE+ E F+ IF ECVLK++AFGF +H G+YLR+GWN++DF++V+ G+++ T + D++ LRA RVLRPL+LVSG+PSLQVV+ SI+ AM PL I LL LF III+AIIGLE +SG HS CY++ + + E P+PC+ TS Y CD ++ + +W GPN GITSFDN G AM+TVFQCITMEGWT +MY+ NDS+G ++ W YF+ LI++GSFF++NLVLGVLSGEF+KERE+ + R ++ K R Q Q + ++ GYL+WI AE++ + +EE + + + K +S+E +D ++ + + + G +++++ C + + ++ R R +VK+Q FYW VI LVFLNT + SEHY Q W F A +F+ +F +EML+K++++G R YF FNRFD V++ S E++ + G+SV+R RLLR+FK+T YW SLRNLV SL+ SM+SI+SLL LLFLFI+IF+LLGMQLFGG+FNF P ++FD+F +L+TVFQILTGEDWNEVMY I S G + +Y+++L + GNY LLNVFLAIAVDNLA+
Sbjct: 170 RKTTLSSNAPVKEKGPSSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQ-----------KWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAYFIPLIVLGSFFMLNLVLGVLSGEFAKERERVENRREFLKLRRQQQIERELNGYLEWILTAEEVILKEDRTTEEEKAAIMEARRRAANKKLKQASKQQSTETEEDFEEDEDEMEEEYVDEGGTVEDEFAERKKRGCCHSVGK-----FIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYG-GSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNF-PTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLANA 856 HSP 3 Score: 122.865 bits (307), Expect = 3.506e-27 Identity = 87/280 (31.07%), Postives = 138/280 (49.29%), Query Frame = 1
Query: 994 GNPRPQ---RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPD-----VKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSF--DNFGLAMLTVFQCITMEGWTQI 1803
G P+P ++F L+ NPFR IV K FE +++ I + +LAA P E N N L+ ++ F +F E +LK++ G ++HPG+Y R+ WN+LD ++V L + + +EG +K+LR RVLRPL+ + +P L+ V + ++ ++ +F+I ++ I+A+I ++LF+GK C KN + C H F Y DN+N+ R + F DN AMLT+F T EGW I
Sbjct: 923 GGPKPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEE--NPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAG-TEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFF-FCTDKNRKFANT---C-------------HGQFFVY---DNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGI 1179 HSP 4 Score: 102.064 bits (253), Expect = 7.280e-21 Identity = 68/233 (29.18%), Postives = 123/233 (52.79%), Query Frame = 1
Query: 4288 EFALKAK-----PVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
EFA + K V ++I + + R+ ++ ++ F + + L+ LNT +A + QPQ + + Y VF G+F VE LLKL A G + YF+ +N FD ++++GS ++I+ V G + I+ R R++R+ KL S +R L+ + + S +++ + L+ + I+A++GMQ+FG ++ +F TFP A++ +F+ TGE W +M
Sbjct: 592 EFAERKKRGCCHSVGKFIKQLRIQIRI--MVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGS--------FGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFG-----GRFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVM 809 HSP 5 Score: 87.0409 bits (214), Expect = 2.624e-16 Identity = 85/367 (23.16%), Postives = 152/367 (41.42%), Query Frame = 1
Query: 997 NPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAA---NTP-YPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIM------------------YWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAA 2031
N RP R+LF +N + ++V PFEY I+ I N L N P + E N+AL +FT E +LKILAFG Y R+GWN DF+ V+ + ++++ + LR FR R +RL+ ++++++ + +++ L ++ LL + IYAI+G+++F ++ + + +T +N+ +F +F A++ +F+C T EGW IM + + G + + YF S + + SF ++NL + V+ F + G + DE ++ + D+ AA
Sbjct: 1254 NARP-RSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTAL-------TAVFTVESILKILAFGV----RNYFRDGWNRFDFVTVVGSITDALVTEFGGHFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVF-----------GNIWLNA----ATEINRH--------------------------------NNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPH-------HLDEFIRVWADYDPAA 1554 HSP 6 Score: 80.1073 bits (196), Expect = 2.994e-14 Identity = 73/309 (23.62%), Postives = 138/309 (44.66%), Query Frame = 1
Query: 1066 IVEWKPFEYLILFTIFAN-CCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMG-ITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVG----MSWPW-IYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKA 1971
+V+ + F + ++ +F N CC + + P+ ++ + A E VF+ IF E +LK+ A G Y + +N D ++++ + +++ G + +RA R+LR +L S SL+ ++ S+M +M + + L I+I+A++G++LF G R++ P M T FD F +A++TVFQ +T E W ++MY +S G WP+ IYF+ L++ G++ ++N+ L + + +E +KA
Sbjct: 619 MVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYA----EFVFLGIFVVEMLLKLFAMG----SRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGG--------------------------------------------------RFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLANAQELTAAEEADEKA 869 HSP 7 Score: 72.4034 bits (176), Expect = 6.914e-12 Identity = 76/281 (27.05%), Postives = 129/281 (45.91%), Query Frame = 1
Query: 3349 SSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAED--PLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLK--RXXXXXXXXXKSIGNIM-------LVTFLLEFMFAVIGVQLFNGKFQSC--NDVSKNTHISCRGQYIYYNEADIA------KVFVNKREWIN---NPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
SS FIF +N R+ I F +L+ I+ + +L+ E P + + + + L + F +F +E LKVI +G H G++ RS NI+D +VV++ +++ + A LR LRA+ + LK + + V +KSI M L+ +FA+IG++ ++G F S N+ + ++S R + + K ++WI +FDN+ AM+T+F T EGW V+Y + DS Y+ Y
Sbjct: 186 SSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAY 466 HSP 8 Score: 67.781 bits (164), Expect = 1.470e-10 Identity = 62/251 (24.70%), Postives = 130/251 (51.79%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKF-NFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYG---------NLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
LV S F + ++ ++ NT +L ++Y ++ + N +FT+E ++K+ + G+R YF +NRFDF V+ SI + ++ + + + LR R R+ ++ + ++R L+ + + S K++ + +L+ + I++++GMQ+FG + N + +NF SF +++ +F+ TGE W ++M ++ N K S +S Y+ ++++LN+F+A+ +DN
Sbjct: 1276 LVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGGH-FVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNF 1525 HSP 9 Score: 63.1586 bits (152), Expect = 4.370e-9 Identity = 55/246 (22.36%), Postives = 107/246 (43.50%), Query Frame = 1
Query: 4375 PFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMV---FTGVFTVEFLLKLAAFGFK----NYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF------------GKITTENEKEMKEINRNN--------------------------NFQTFPQAILVLFRSATGEAWQNIMLH 4977
PFEY I + I+ N + L+++ + + ++L F G+F +E +LK+ AFGF +Y WN+ DFI+V+ + ++ N D + + R RV+R +KL+S ++ +L + + + L + LL++ I+A+IG++ + G+I +E+ M N+ + +F A++ +F+ T E W +M +
Sbjct: 209 PFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDS-VDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYY 453
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1D (gene:FBgn0001991 transcript:FBtr0332020) HSP 1 Score: 1739.93 bits (4505), Expect = 0.000e+0 Identity = 996/1701 (58.55%), Postives = 1194/1701 (70.19%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPV-PCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIY--------------DHVNGTNNNHR--GDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHC--LPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDD-VTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGST--RRDSNASPS 6000
R R + RPQRALFCL+++NP R CI+IVEWKPFE+LIL TIFANC ALA TPYP DSN N LEK+E VF+VIFT ECV+KILA+GF++H GAYLRNGWNLLDF IV+IG IST LS++ + DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPLFHIALL LFVIIIYAIIGLELFSGKLH C + E + PC GYQC Y C W GPN GIT+FDNFGLAMLTVFQC+T+EGWT ++Y I D++G W W+YF+S++I+G+FFVMNL+LGVLSGEFSKER KAK RG +QK RE+ Q +ED++GYLDWI AEDI D +GK + ++ E G Q +K R R R + + ++ +++ LVFLNTGVL +EHY Q WLD+FQ N+ F+ LFT EML+KMYSLG + YF +FNRFD FVVI SI E ++ T MPPLGVSVLRC RLLRVFKVT+YW SL NLV SLL S++SI SLL+LLFLFIVIF+LLGMQ+FGGKFNFD K+ K R NFD F Q+LLTVFQI+TGEDWN VMY GI +YG + L+C+Y++ILFICGNYILLNVFLAIAVDNLAD S ++ EK+E + +E+ S + +P ID + ++ +E++ DE T D E E E T+ RR+SEV K+ KPIP S+FFIF N+FR FCH++CNH +FGNI+L CIM SSAMLAAE+PL A N++LN FDY FT+VFT+E+ LK+I+YG V H+GAFCRS+ N+LDLLVV S+IS +++AISVVKILRVLRVLRPLRAINRAKGLK VV+CVVVA+K+IGNIMLVT+LL+FMFAVIGVQLF GKF C D SK T C G Y+ Y++ D+ K + +REW NN +FD+V MLTLF VSTFEGWPG+LY SIDS KE+ I+N RPIV+ +YI YII+IAFFM+NIFVGFVIVTFQ EGE+EYKNC+LDKNQR CIEFALKAKPVRRYIPK +Y+VWW +TS FEY IF+LIM+NT++LA+KF QP Y +++D LNM+FT VF +EF+ KLAAF FKNYF DAWNVFDFIIVLGSFIDI+Y D V G + + G LISINFFRLFRVMRLVKLLS+GEGIRTLLWTF+KSFQALPYVALLIV+LFFIYAV+GMQ+FGKI + I NNNFQTF QA+LVLFRSATGEAWQ IM+ C PD CD SD + CGS+ AYPYFISFY++CSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF+RLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV+FNATLFA+VRT+L IKTDG+ +D N ELR IK+IWKRT+ K+LDQVVPP GNDD VTVGKFYAT+LIQ++FRR+K KR E++ + S ++L RT S L IS L DE D++ P H RR H++FG++ + ++R G+ RR + A+ S
Sbjct: 611 RQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRDEITGEYEENIRPCGV----GYQCPP------GYKCYGG------WDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDAVGGLISDGKGKQ-------------------PNEMDSTENLGEEMPEVQMTESRWRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIV-LVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPH----------DESAQKKSHSPTPTIDGMDDHLSIDIDMEQQELD----DEDKMDHETLSDEEVREMCEEEEEVSARV----TARPRRLSEVSMKKTKKPIPRGSAFFIFSYTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKYVVKCVVVAIKTIGNIMLVTYLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGG---NAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDTPGE----------------------------------------------PCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGN-IDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFK-KRKEQEGKEGHPDSNTVTLQAGLRTLHEVSPALKRAISGNL------DELDQEPEPMH----RRHHTLFGSVWSSIRRHGNGTFRRSAKATAS 2196 HSP 2 Score: 118.242 bits (295), Expect = 1.026e-25 Identity = 97/349 (27.79%), Postives = 163/349 (46.70%), Query Frame = 1
Query: 937 LSAQIASGGRKRTP-ARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLII---------IGSFFVMNLVLGVLSGEFSKEREKAKK 1950
+SA++ + R+ + + ++ P P+ A F + N FR FC + F +IL I + LAA P R ++ +N L K + F +FT E +LK++++GF++H GA+ R+ +NLLD L+V + L S VK LR RVLRPLR ++ L+ V+ ++ A+ + +I L+ + ++A+IG++LF GK C + + + + G D H + WS FD+ MLT+F T EGW ++Y DS + I+ I+ I +FF++N+ +G + F E E+ K
Sbjct: 1325 VSARVTARPRRLSEVSMKKTKKPIPRGSAFFIFSYTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPL--RANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVC--VSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKYVVKCVVVAIKTIGNIMLVTYLLQFMFAVIGVQLFKGKFFK-CTDGSKMTQDECYGTYLVYDDG----DVHKPRLR---------EREWSNNRF---HFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYK 1652
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1D (gene:FBgn0001991 transcript:FBtr0090005) HSP 1 Score: 1736.85 bits (4497), Expect = 0.000e+0 Identity = 998/1702 (58.64%), Postives = 1197/1702 (70.33%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPV-PCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSA-IRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIY--------------DHVNGTNNNHR--GDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHC--LPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDD-VTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGST--RRDSNASPS 6000
R R + RPQRALFCL+++NP R CI+IVEWKPFE+LIL TIFANC ALA TPYP DSN N LEK+E VF+VIFT ECV+KILA+GF++H GAYLRNGWNLLDF IV+IG IST LS++ + DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPLFHIALL LFVIIIYAIIGLELFSGKLH C + E + PC GYQC Y C W GPN GIT+FDNFGLAMLTVFQC+T+EGWT ++Y I D++G W W+YF+S++I+G+FFVMNL+LGVLSGEFSKER KAK RG +QK RE+ Q +ED++GYLDWI AEDI D +GK + ++ E G Q +K R R R + + ++ +++ LVFLNTGVL +EHY Q WLD+FQ N+ F+ LFT EML+KMYSLG + YF +FNRFD FVVI SI E ++ T MPPLGVSVLRC RLLRVFKVT+YW SL NLV SLL S++SI SLL+LLFLFIVIF+LLGMQ+FGGKFNFD K+ K R NFD F Q+LLTVFQI+TGEDWN VMY GI +YG + L+C+Y++ILFICGNYILLNVFLAIAVDNLAD S ++ EK+E + +E+ S + +P ID + ++ +E++ DE T D E E E D E + + +A RR+SEV K+ KPIP S+FFIF N+FR FCH++CNH +FGNI+L CIM SSAMLAAE+PL A N++LN FDY FT+VFT+E+ LK+I+YG V H+GAFCRS+ N+LDLLVV S+IS +++AISVVKILRVLRVLRPLRAINRAKGLK VVQCV+VAVK+IGNI+LVT LL+FMFAVIGVQLF GKF C D SK T C G Y+ Y++ D+ K + +REW NN +FD+V MLTLF VSTFEGWPG+LY SIDS KE+ I+N RPIV+ +YI YII+IAFFM+NIFVGFVIVTFQ EGE+EYKNC+LDKNQR CIEFALKAKPVRRYIPK +Y+VWW +TS FEY IF+LIM+NT++LA+KF QP Y +++D LNM+FT VF +EF+ KLAAF FKNYF DAWNVFDFIIVLGSFIDI+Y D V G + + G LISINFFRLFRVMRLVKLLS+GEGIRTLLWTF+KSFQALPYVALLIV+LFFIYAV+GMQ+FGKI + I NNNFQTF QA+LVLFRSATGEAWQ IM+ C PD CD SD + CGS+ AYPYFISFY++CSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF+RLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV+FNATLFA+VRT+L IKTDG+ +D N ELR IK+IWKRT+ K+LDQVVPP GNDD VTVGKFYAT+LIQ++FRR+K KR E++ + S ++L RT S L IS L DE D++ P H RR H++FG++ + ++R G+ RR + A+ S
Sbjct: 579 RQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRDEITGEYEENIRPCGV----GYQCPP------GYKCYGG------WDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDAVGGLISDGKGKQ-------------------PNEMDSTENLGEEMPEVQMTESRWRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIV-LVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPH----------DESAQKKSHSPTPTIDGMDDHLSIDIDMEQQELD----DEDKMDHETLSDEEVREMCEEEEEDSNSEVSARVTARPRRLSEVSMKKTKKPIPRGSAFFIFSYTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGG---NAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDTPGE----------------------------------------------PCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGN-IDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFK-KRKEQEGKEGHPDSNTVTLQAGLRTLHEVSPALKRAISGNL------DELDQEPEPMH----RRHHTLFGSVWSSIRRHGNGTFRRSAKATAS 2169 HSP 2 Score: 118.242 bits (295), Expect = 1.220e-25 Identity = 98/355 (27.61%), Postives = 164/355 (46.20%), Query Frame = 1
Query: 937 LSAQIASGGRKRTP-ARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLII---------IGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQK 1968
+SA++ + R+ + + ++ P P+ A F + N FR FC + F +IL I + LAA P R ++ +N L K + F +FT E +LK++++GF++H GA+ R+ +NLLD L+V + L S VK LR RVLRPLR ++ L+ V+ ++ A+ + +I L+ + ++A+IG++LF GK C + + + + G D H + WS FD+ MLT+F T EGW ++Y DS + I+ I+ I +FF++N+ +G + F E E+ K K
Sbjct: 1298 VSARVTARPRRLSEVSMKKTKKPIPRGSAFFIFSYTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPL--RANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVC--VSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFK-CTDGSKMTQDECYGTYLVYDDG----DVHKPRLR---------EREWSNNRF---HFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDK 1631
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1D (gene:FBgn0001991 transcript:FBtr0332024) HSP 1 Score: 1733 bits (4487), Expect = 0.000e+0 Identity = 998/1702 (58.64%), Postives = 1197/1702 (70.33%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPV-PCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSA-IRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIY--------------DHVNGTNNNHR--GDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHC--LPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDD-VTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGST--RRDSNASPS 6000
R R + RPQRALFCL+++NP R CI+IVEWKPFE+LIL TIFANC ALA TPYP DSN N LEK+E VF+VIFT ECV+KILA+GF++H GAYLRNGWNLLDF IV+IG IST LS++ + DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPLFHIALL LFVIIIYAIIGLELFSGKLH C + E + PC GYQC Y C W GPN GIT+FDNFGLAMLTVFQC+T+EGWT ++Y I D++G W W+YF+S++I+G+FFVMNL+LGVLSGEFSKER KAK RG +QK RE+ Q +ED++GYLDWI AEDI D +GK + ++ E G Q +K R R R + + ++ +++ LVFLNTGVL +EHY Q WLD+FQ N+ F+ LFT EML+KMYSLG + YF +FNRFD FVVI SI E ++ T MPPLGVSVLRC RLLRVFKVT+YW SL NLV SLL S++SI SLL+LLFLFIVIF+LLGMQ+FGGKFNFD K+ K R NFD F Q+LLTVFQI+TGEDWN VMY GI +YG + L+C+Y++ILFICGNYILLNVFLAIAVDNLAD S ++ EK+E + +E+ S + +P ID + ++ +E++ DE T D E E E D E + + +A RR+SEV K+ KPIP S+FFIF N+FR FCH++CNH +FGNI+L CIM SSAMLAAE+PL A N++LN FDY FT+VFT+E+ LK+I+YG V H+GAFCRS+ N+LDLLVV S+IS +++AISVVKILRVLRVLRPLRAINRAKGLK VVQCV+VAVK+IGNI+LVT LL+FMFAVIGVQLF GKF C D SK T C G Y+ Y++ D+ K + +REW NN +FD+V MLTLF VSTFEGWPG+LY SIDS KE+ I+N RPIV+ +YI YII+IAFFM+NIFVGFVIVTFQ EGE+EYKNC+LDKNQR CIEFALKAKPVRRYIPK +Y+VWW +TS FEY IF+LIM+NT++LA+KF QP Y +++D LNM+FT VF +EF+ KLAAF FKNYF DAWNVFDFIIVLGSFIDI+Y D V G + + G LISINFFRLFRVMRLVKLLS+GEGIRTLLWTF+KSFQALPYVALLIV+LFFIYAV+GMQ+FGKI + I NNNFQTF QA+LVLFRSATGEAWQ IM+ C PD CD SD + CGS+ AYPYFISFY++CSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF+RLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV+FNATLFA+VRT+L IKTDG+ +D N ELR IK+IWKRT+ K+LDQVVPP GNDD VTVGKFYAT+LIQ++FRR+K KR E++ + S ++L RT S L IS L DE D++ P H RR H++FG++ + ++R G+ RR + A+ S
Sbjct: 86 RQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRDEITGEYEENIRPCGV----GYQCPP------GYKCYGG------WDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDAVGGLISDGKGKQ-------------------PNEMDSTENLGEEMPEVQMTESRWRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIV-LVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPH----------DESAQKKSHSPTPTIDGMDDHLSIDIDMEQQELD----DEDKMDHETLSDEEVREMCEEEEEDSNSEVSARVTARPRRLSEVSMKKTKKPIPRGSAFFIFSYTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGG---NAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDTPGE----------------------------------------------PCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGN-IDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFK-KRKEQEGKEGHPDSNTVTLQAGLRTLHEVSPALKRAISGNL------DELDQEPEPMH----RRHHTLFGSVWSSIRRHGNGTFRRSAKATAS 1676 HSP 2 Score: 117.472 bits (293), Expect = 1.874e-25 Identity = 98/355 (27.61%), Postives = 164/355 (46.20%), Query Frame = 1
Query: 937 LSAQIASGGRKRTP-ARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLII---------IGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQK 1968
+SA++ + R+ + + ++ P P+ A F + N FR FC + F +IL I + LAA P R ++ +N L K + F +FT E +LK++++GF++H GA+ R+ +NLLD L+V + L S VK LR RVLRPLR ++ L+ V+ ++ A+ + +I L+ + ++A+IG++LF GK C + + + + G D H + WS FD+ MLT+F T EGW ++Y DS + I+ I+ I +FF++N+ +G + F E E+ K K
Sbjct: 805 VSARVTARPRRLSEVSMKKTKKPIPRGSAFFIFSYTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPL--RANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVC--VSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFK-CTDGSKMTQDECYGTYLVYDDG----DVHKPRLR---------EREWSNNRF---HFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDK 1138
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1D (gene:FBgn0001991 transcript:FBtr0090006) HSP 1 Score: 1732.61 bits (4486), Expect = 0.000e+0 Identity = 999/1701 (58.73%), Postives = 1200/1701 (70.55%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPV-PCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIY--------------DHVNGTNNNHR--GDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHC--LPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDD-VTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGST--RRDSNASPS 6000
R R + RPQRALFCL+++NP R CI+IVEWKPFE+LIL TIFANC ALA TPYP DSN N LEK+E VF+VIFT ECV+KILA+GF++H GAYLRNGWNLLDF IV+IG IST LS++ + DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPLFHIALL LFVIIIYAIIGLELFSGKLH C + E + PC GYQC Y C W GPN GIT+FDNFGLAMLTVFQC+T+EGWT ++Y I D++G W W+YF+S++I+G+FFVMNL+LGVLSGEFSKER KAK RG +QK RE+ Q +ED++GYLDWI AEDI D +GK + ++ E G Q +K R R R + + ++ +++ LVFLNTGVL +EHY Q WLD+FQ N+ F+ LFT EML+KMYSLG + YF +FNRFD FVVI SI E ++ T MPPLGVSVLRC RLLRVFKVT+YW SL NLV SLL S++SI SLL+LLFLFIVIF+LLGMQ+FGGKFNFD K+ K R NFD F Q+LLTVFQI+TGEDWN VMY GI +YG + L+C+Y++ILFICGNYILLNVFLAIAVDNLAD S ++ EK+E + +E+ S + +P ID + ++ +E++ DE KM +++E E E +E DEE T+ RR+SEV KI PIP +SFF+F N+FR FCH++CNH +FGNI+L CIM SSAMLAAE+PL A N++LN FDY FT+VFT+E+ LK+I+YG V H+GAFCRS+ N+LDLLVV S+IS +++AISVVKILRVLRVLRPLRAINRAKGLK VVQCV+VAVK+IGNI+LVT LL+FMFAVIGVQLF GKF C D SK T C G Y+ Y++ D+ K + +REW NN +FD+V MLTLF VSTFEGWPG+LY SIDS KE+ I+N RPIV+ +YI YII+IAFFM+NIFVGFVIVTFQ EGE+EYKNC+LDKNQR CIEFALKAKPVRRYIPK +Y+VWW +TS FEY IF+LIM+NT++LA+KF QP Y +++D LNM+FT VF +EF+ KLAAF FKNYF DAWNVFDFIIVLGSFIDI+Y D V G + + G LISINFFRLFRVMRLVKLLS+GEGIRTLLWTF+KSFQALPYVALLIV+LFFIYAV+GMQ+FGKI + I NNNFQTF QA+LVLFRSATGEAWQ IM+ C PD CD SD + CGS+ AYPYFISFY++CSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF+RLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV+FNATLFA+VRT+L IKTDG+ +D N ELR IK+IWKRT+ K+LDQVVPP GNDD VTVGKFYAT+LIQ++FRR+K KR E++ + S ++L RT S L IS L DE D++ P H RR H++FG++ + ++R G+ RR + A+ S
Sbjct: 579 RQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRDEITGEYEENIRPCGV----GYQCPP------GYKCYGG------WDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDAVGGLISDGKGKQ-------------------PNEMDSTENLGEEMPEVQMTESRWRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIV-LVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPH----------DESAQKKSHSPTPTIDGMDDHLSIDIDMEQQELD----DED--KMDHETLSDEEVREMCEEEEEVDEEGMITARPRRMSEVNTATKILPIPPGTSFFLFSQTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGG---NAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDTPGE----------------------------------------------PCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGN-IDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFK-KRKEQEGKEGHPDSNTVTLQAGLRTLHEVSPALKRAISGNL------DELDQEPEPMH----RRHHTLFGSVWSSIRRHGNGTFRRSAKATAS 2166
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Fly
Match: Ca-alpha1D (gene:FBgn0001991 transcript:FBtr0332023) HSP 1 Score: 1730.69 bits (4481), Expect = 0.000e+0 Identity = 999/1701 (58.73%), Postives = 1201/1701 (70.61%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPV-PCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIY--------------DHVNGTNNNHR--GDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHC--LPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDD-VTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGST--RRDSNASPS 6000
R R + RPQRALFCL+++NP R CI+IVEWKPFE+LIL TIFANC ALA TPYP DSN N LEK+E VF+VIFT ECV+KILA+GF++H GAYLRNGWNLLDF IV+IG IST LS++ + DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPLFHIALL LFVIIIYAIIGLELFSGKLH C + E + PC GYQC Y C W GPN GIT+FDNFGLAMLTVFQC+T+EGWT ++Y I D++G W W+YF+S++I+G+FFVMNL+LGVLSGEFSKER KAK RG +QK RE+ Q +ED++GYLDWI AEDI D +GK + ++ E G Q +K R R R + + ++ +++ LVFLNTGVL +EHY Q WLD+FQ N+ F+ LFT EML+KMYSLG + YF +FNRFD FVVI SI E ++ T MPPLGVSVLRC RLLRVFKVT+YW SL NLV SLL S++SI SLL+LLFLFIVIF+LLGMQ+FGGKFNFD K+ K R NFD F Q+LLTVFQI+TGEDWN VMY GI +YG + L+C+Y++ILFICGNYILLNVFLAIAVDNLAD S ++ EK+E + +E+ S + +P ID + ++ +E++ DE KM +++E E E +E DEE T+ RR+SEV KI PIP +SFF+F N+FR FCH++CNH +FGNI+L CIM SSAMLAAE+PL A N++LN FDY FT+VFT+E+ LK+I+YG V H+GAFCRS+ N+LDLLVV S+IS +++AISVVKILRVLRVLRPLRAINRAKGLK VV+CVVVA+K+IGNIMLVT+LL+FMFAVIGVQLF GKF C D SK T C G Y+ Y++ D+ K + +REW NN +FD+V MLTLF VSTFEGWPG+LY SIDS KE+ I+N RPIV+ +YI YII+IAFFM+NIFVGFVIVTFQ EGE+EYKNC+LDKNQR CIEFALKAKPVRRYIPK +Y+VWW +TS FEY IF+LIM+NT++LA+KF QP Y +++D LNM+FT VF +EF+ KLAAF FKNYF DAWNVFDFIIVLGSFIDI+Y D V G + + G LISINFFRLFRVMRLVKLLS+GEGIRTLLWTF+KSFQALPYVALLIV+LFFIYAV+GMQ+FGKI + I NNNFQTF QA+LVLFRSATGEAWQ IM+ C PD CD SD + CGS+ AYPYFISFY++CSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF+RLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV+FNATLFA+VRT+L IKTDG+ +D N ELR IK+IWKRT+ K+LDQVVPP GNDD VTVGKFYAT+LIQ++FRR+K KR E++ + S ++L RT S L IS L DE D++ P H RR H++FG++ + ++R G+ RR + A+ S
Sbjct: 86 RQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRDEITGEYEENIRPCGV----GYQCPP------GYKCYGG------WDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDAVGGLISDGKGKQ-------------------PNEMDSTENLGEEMPEVQMTESRWRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIV-LVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPH----------DESAQKKSHSPTPTIDGMDDHLSIDIDMEQQELD----DED--KMDHETLSDEEVREMCEEEEEVDEEGMITARPRRMSEVNTATKILPIPPGTSFFLFSQTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKYVVKCVVVAIKTIGNIMLVTYLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGG---NAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDTPGE----------------------------------------------PCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGN-IDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFK-KRKEQEGKEGHPDSNTVTLQAGLRTLHEVSPALKRAISGNL------DELDQEPEPMH----RRHHTLFGSVWSSIRRHGNGTFRRSAKATAS 1673
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1sb (calcium channel, voltage-dependent, L type, alpha 1S subunit, b [Source:ZFIN;Acc:ZDB-GENE-051227-1]) HSP 1 Score: 1520.37 bits (3935), Expect = 0.000e+0 Identity = 875/1693 (51.68%), Postives = 1129/1693 (66.69%), Query Frame = 1
Query: 985 SQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVL---------SKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMM-----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMS------TRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRG--------------------DRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGP-LISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFG 5937
+ GNPRP R LF LRNPFRK C IVEWKPFE +IL TIFANC ALA P PE D+N N LE +E +F+VIFT EC LKI+A+G + H GAYLRN WN+LDF+IV +GL + V+ K GG D+KALRAFRVLRPLRLVSG+PSLQVVM+S++++M+PLFHI LL F++ IYAI+GLELF K+H TCY + ++ E P PC+ + N G +C + C+D W GPN GIT FDNFG AMLTVFQCIT E WT ++YWIND++G WPWIYF+SLI++GSFF++NLVLGVLSGEF+KEREK++ RG++Q RE+ Q DED++GY++WI A E DG + K G ET+ + V+ + L R R+C VKS++F W V+++V LNT V+ +EH+ Q+ L +FQ+TAN+I + FT+EM++KMY+ G R YF +FNRFD FVV ILEI+++ + M PLG+SV+RC RLLR+FK+T+YW+SL NLV SLL S+KSI SLL+LLFLFIVIF+LLGMQ+FGGKFNF + RSNFD+F Q+L++VFQ+LTGE+W+ +MY+GI ++G +L +Y++IL++CGN++LLNVFLAIAVDNLA+ S +K+ EE P E+ + A+RL++S + + + K+ + + + +EE+ E + R ++++ KE + P+P ASSFFIFGP NKFRK CH I NH F NI+L+ I++SS LAAEDP+D S RN++L Y D +FT+VFT+EI LK+ YG H G+FCR+S NILDL+VV S++S + + ISVVKILRVLRVLRPLRAINRAKGLK VVQC+ VA+K+IGNI+LVT LL+FMF+ IGVQLF G C D + T C+G ++ + + + +++R W+N+ NFDNV N ML LF +STFEGWP +LYK+IDS+ D +YNNR +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+++ALKA+P++ YIP+ +YRVW+L+TS FEY++F LIMLNT+SL +++ QP ++ D LN++FT +FT E ++KL AF K YF D WNVFDF+IV+GS +D++ V+ T G + +SI FFRLFRV+RL+KLL+R EGIR LLWTF+KSFQALP+V LLIVMLFFIYAVIGMQMFGKI + EINRNNNFQTFPQA+L+LFR ATGE W IML + +CD SD E Y CGS+ A YF+SFYM+C+FL+INLFVA+IMDNFDYLT DWSILGPHHLDEF ++W EYDPEA GRIKHLDVVTLLR+I PPLGFGK+CPH AC L+ MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IK IWKRTS K+LDQV+PP G D+VTVGKFYATFLIQE FR++ Q R EE G ++ + R+ + P L IS L+ DE ++ G RRT +FG
Sbjct: 43 ATGGNPRPPRTLFFFKLRNPFRKACTNIVEWKPFEIIILLTIFANCVALAVFLPMPEEDTNNTNLTLESLEYIFLVIFTLECFLKIIAYGLLFHEGAYLRNCWNILDFVIVFMGLFTLVVDTIDTITGVQKEKGGGFDMKALRAFRVLRPLRLVSGVPSLQVVMSSVLKSMLPLFHILLLVFFMVTIYAIMGLELFKCKMHKTCYYQGTNIIALRENEKPSPCAQAGN-GRRCTINGTE-----CRDG------WPGPNFGITHFDNFGFAMLTVFQCITTESWTDVLYWINDAMGNDWPWIYFLSLIMLGSFFILNLVLGVLSGEFTKEREKSRSRGEWQVLRERQQMDEDLKGYMEWITHA------EVMDGDSDAMLLLRKDTG--------------------SETDSLYKMEGINKVVYFYRLARRWNIVIRRKCHG----WVKSKSFNWWVLIVVLLNTLVIATEHHNQTEGLTNFQDTANVILLACFTIEMIMKMYAFGPRSYFMSIFNRFDCFVVTIGILEIILVGSGIMTPLGISVMRCIRLLRLFKLTKYWTSLNNLVVSLLNSVKSIASLLLLLFLFIVIFALLGMQVFGGKFNFPDRPIQRSNFDNFPQALISVFQVLTGEEWDTIMYNGIMAHGGPKSPGILVSIYFIILYVCGNFVLLNVFLAIAVDNLAEAESLAAAQKER------------AEERARKKLMKPLPEKTEEEKALMAKRLMESRQKTEGMPTTAKLKIDEFESNVNEVKDPFPPADFPGDDEEEEPEIPISPRPRPMADLQLKETVVPMPEASSFFIFGPQNKFRKLCHRIINHTTFTNIILLFILLSSISLAAEDPIDPHSFRNKVLAYADIVFTTVFTIEIVLKMTVYGAFLHPGSFCRNSFNILDLIVVAVSLLSMGMESSTISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAIKTIGNIVLVTMLLDFMFSCIGVQLFKGTLFYCTDPLQKTAEQCQGTFLKHVQNSLHDTEIHQRRWVNSDFNFDNVLNGMLALFTISTFEGWPEILYKAIDSYDVDTGPLYNNRVGISIFFIIYIIIIAFFMMNIFVGFVIVTFQRQGEQEYKNCELDKNQRQCVQYALKARPLKCYIPENPHQYRVWYLVTSCYFEYLMFFLIMLNTLSLGMQYCNQPFYITKLSDNLNVIFTVLFTGEMIVKLIAFKAKGYFGDPWNVFDFVIVIGSIVDVVLSEVDRTLEASGGLWCLHGCSEVDPMQAIAEAENVKLSITFFRLFRVLRLIKLLNRSEGIRNLLWTFIKSFQALPHVGLLIVMLFFIYAVIGMQMFGKIALVDG---TEINRNNNFQTFPQAVLLLFRVATGEQWPKIMLASMYGKLCDPKSDYGPGEEYT-------------------------------------------CGSSIAVCYFLSFYMLCAFLVINLFVAIIMDNFDYLTHDWSILGPHHLDEFKKIWGEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCPHHAACKRLISMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKSIWKRTSMKLLDQVIPPIGEDEVTVGKFYATFLIQEHFRKFMQ-RQEELYGYRPTKKNADEIKAGLRSIEEEAAPELHRAISGDLIAE---DEMERAMESGEEGIYRRTGGLFG 1630 HSP 2 Score: 83.1889 bits (204), Expect = 6.353e-15 Identity = 100/445 (22.47%), Postives = 175/445 (39.33%), Query Frame = 1
Query: 4237 EEEYKNCELDKNQRKCIEFALKAKPVRR---YIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQR----YEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVN---GTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF--------------------------------GKITTENEKEMKEINRNNN-----FQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTR------DWSILGP-HHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRK 5397
EEE K + +K +K + +P R + + FR ++ +PFE II + I N ++LA+ F P+ ++ L +F +FT+E LK+ A+G Y + WN+ DF+IV ++ D ++ G G + R FRV+R ++L+S ++ ++ + +KS L ++ LL+ + IYA++G+++F G+ T N E ++ N F F A+L +F+ T E+W ++ L+ + DAM ND WP + YF+S M+ SF I+NL + V+ F +W +L +DE ++ + E+ A+ D + LLRK
Sbjct: 27 EEELKRKQREK-LKKLLATGGNPRPPRTLFFFKLRNPFRKACTNIVEWKPFEIIILLTIFANCVALAV-FLPMPEEDTNNTNLTLESLEYIFLVIFTLECFLKIIAYGLLFHEGAYLRNCWNILDFVIVFMGLFTLVVDTIDTITGVQKEKGGG--FDMKALRAFRVLRPLRLVSGVPSLQVVMSSVLKSMLPLFHILLLVFFMVTIYAIMGLELFKCKMHKTCYYQGTNIIALRENEKPSPCAQAGNGRRCTINGTECRDGWPGPNFGITHFDNFGFAMLTVFQCITTESWTDV-LYWINDAMG---------------------------ND----WP---------------------------WIYFLSLIMLGSFFILNLVLGVLSGEFTKEREKSRSRGEWQVLRERQQMDEDLKGYMEWITHAEVMDGDSDAMLLLRK 408
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1da (calcium channel, voltage-dependent, L type, alpha 1D subunit, a [Source:ZFIN;Acc:ZDB-GENE-030616-135]) HSP 1 Score: 989.949 bits (2558), Expect = 0.000e+0 Identity = 550/916 (60.04%), Postives = 666/916 (72.71%), Query Frame = 1
Query: 3298 RVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDK---DYLPSH-LGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELP 6033
++SE++ KEKI PIP S+FFIF N R CH + NH F N++LV IM+SSA LAAEDP+ S+RN IL YFDY FT++FTVEI LK+ TYG H GAFCR+ N+LDLLVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF CND +K++ C+G YI Y E D+ + + KR W N+ NFDNV AM+ LF VSTFEGWP +LYK+IDS +E+ IYN R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S FEYI+FVLI+LNTI LA++ Q + + VMD LNMVFT VFTVE +LKL AF ++YF+DAWN FD +IV+GS +DI VN T ++ R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQ+FGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C+P +CD SD YN P CGS+FA YFI+FYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ ++Q NEELR VIKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQ++FR++K+++ E G+ +Q+ + + + I P + CD +D D++P RR +FG +N + G RR S+G ++T+ P
Sbjct: 790 KISELVKKEKITPIPEGSAFFIFSNTNPVRVACHKLINHHIFTNLILVFIMLSSASLAAEDPIRNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYIMYKEGDVNQPIIQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNRENMGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLILLNTICLAVQHYGQSELFNYVMDILNMVFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSAR----ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDH---TQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMPGKLCDPESD------YN---------------------PGEEMT----------------CGSSFAIIYFITFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LEQANEELRAVIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEEGLVGVHPAQNNTAIAL------QAGLRTLHDIGPEIRRAISCDLQDDELVDFIPEEDEEIYRRNGGLFGNHINHIN--GDPRR------SSGHQTNATQRP 1640 HSP 2 Score: 719.924 bits (1857), Expect = 0.000e+0 Identity = 403/729 (55.28%), Postives = 501/729 (68.72%), Query Frame = 1
Query: 943 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSE---------------------GGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGL-----------CKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXL--------VKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
AQ ++ + S N RPQRALFCL L NP R+ CI +VEWKPF+ IL IFANC ALA P+PE DSN+ N LE +E F++IFT E LKI+A+G +MH AY+RNGWN+LDF+IV+IGL S VL +++ GG DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H++CY D++ + P PC+ + G C + +CK+ W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND++G+ PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI D E + +E K +R L L +SS+ ++ ++ E E G + ++ C P + + R R RL VKS FYW+VI+LVFLNT ++SEHY Q +WL Q+ AN + + +FT EML+KMYSLG++ YF +FNRFD FVV I E ++++ + M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQ+FGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD S
Sbjct: 33 AQKKRAQYAKSKKQGSSANTRPQRALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYVPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKEGGEKEEVGENLSAHGHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHASCYFQGTDILEDEPAPCAVN-GHGRTCPINGT-----LCKEG------WQGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGLELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDI-DPENEEEEEESKRNRVTLASLMEKKKKGFGWFSQSSDTHASMPASETESMNTENEKG----EDEKATCCGPTCQKISKSKFSRRWRRWNRLCRRNCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLAMFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVEFEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES 744 HSP 3 Score: 120.553 bits (301), Expect = 2.596e-26 Identity = 105/337 (31.16%), Postives = 159/337 (47.18%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
P P+ A F + NP R C K++ F LIL I + +LAA P R+ + N L + F IFT E VLK+ +G +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y ND SP C + Y+ D + + W + +FDN +AM+ +F T EGW ++Y DS + IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 802 PIPEGSAFFIFSNTNPVRVACHKLINHHIFTNLILVFIMLSSASLAAEDPI--RNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCNDEAKSSPEECKGTYIM-YKEGDVNQPII---------QKRHWHNSDF---NFDNVLMAMMALFTVSTFEGWPALLYKAIDSNRENMGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1117 HSP 4 Score: 95.9005 bits (237), Expect = 9.472e-19 Identity = 72/256 (28.12%), Postives = 124/256 (48.44%), Query Frame = 1
Query: 4237 EEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSF--RYRVW---------WLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
E E N E +K + E A P + I K F R+R W + S PF +++ +L+ LNT++++ + QP QV D N V +FT E L+K+ + G + YF +N FD +V G + I + + I+ FR R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQA+L +F+ TGE W +M
Sbjct: 454 ETESMNTENEKGED---EKATCCGPTCQKISKSKFSRRWRRWNRLCRRNCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLAMFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVEFEIMSP-------LGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKR----STFDNFPQALLTVFQILTGEDWNAVM 695 HSP 5 Score: 93.5893 bits (231), Expect = 3.757e-18 Identity = 68/252 (26.98%), Postives = 139/252 (55.16%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQ---TDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMYDGI-------RSYGNLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ VL+ LNT L +HY QS + + N++F +FT+EM++K+ + R YF +N FD +V+ S+++I + + T+ + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R +NF +F Q++L +F+ TGE W E+M + S N G+ S + +Y++ ++ ++++N+F+A+ +DN
Sbjct: 1144 VVNSTGFEYIMFVLILLNTICLAVQHYGQSELFNYVMDILNMVFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDHTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMPGKLCDPESDYNPGEEMTCGSSFAIIYFITFYMLCAFLIINLFVAVIMDNF 1395 HSP 6 Score: 88.9669 bits (219), Expect = 1.167e-16 Identity = 75/316 (23.73%), Postives = 137/316 (43.35%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKA----LRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWI----------------NDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEY++ I N LA S N ++ + +VF +FT E VLK++AF P Y + WN D LIV+ ++ +++++ + R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+ M++ T +N+ N N F F A+L +F+C T E W +IM + G S+ IYF++ ++ +F ++NL + V+ F
Sbjct: 1134 KNPYQYKFWYVVNSTGFEYIMFVLILLNTICLAVQH---YGQSELFNYVMDILNMVFTAVFTVEMVLKLIAF----KPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVF-GKI---------AMVD-----HTQINR------------------NNN--------------FQTFPQAVLLLFRCATGEAWQEIMLACMPGKLCDPESDYNPGEEMTCGSSFAIIYFITFYMLCAFLIINLFVAVIMDNF 1395 HSP 7 Score: 78.1814 bits (191), Expect = 2.222e-13 Identity = 62/265 (23.40%), Postives = 116/265 (43.77%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYD------------HVNGTNNNHRGD-RLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-----------GKITTENEKEMKEINRN----------------------NNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
L+ +PF+ I + I N ++LA+ + ++ + F +FT+E LK+ A+G Y + WN+ DF+IV+ ++ + N + + H G + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G E+E +N + NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 74 LVEWKPFDIFILIAIFANCMALAVYVPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKEGGEKEEVGENLSAHGHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHASCYFQGTDILEDEPAPCAVNGHGRTCPINGTLCKEGWQGPNGGITNFDNFMFAMLTVFQCITMEGWTDV-LYWMNDAM 337 HSP 8 Score: 77.0258 bits (188), Expect = 4.207e-13 Identity = 79/299 (26.42%), Postives = 123/299 (41.14%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPI--------------------NNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNK------------REWINNP----LNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
+ F NN R+ C + F +L+ I + LA P D +S N L +Y F +FT+E LK+I YGLV H A+ R+ N+LD ++V+ + S + + ++ LR R LR + G+ + + +K++ ++ + L+ F ++A+IG++LF GK H SC Q E + A VN +E P NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 57 ALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYVPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKEGGEKEEVGENLSAHGHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKM----------HASCYFQGTDILEDEPAPCAVNGHGRTCPINGTLCKEGWQGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGLELPWVY 345
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1da (calcium channel, voltage-dependent, L type, alpha 1D subunit, a [Source:ZFIN;Acc:ZDB-GENE-030616-135]) HSP 1 Score: 980.704 bits (2534), Expect = 0.000e+0 Identity = 548/923 (59.37%), Postives = 664/923 (71.94%), Query Frame = 1
Query: 3298 RVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGT-------NNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDK---DYLPSH-LGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELP 6033
++SE++ KEKI PIP S+FFIF N R CH + NH F N++LV IM+SSA LAAEDP+ S+RN +L Y DY+FTS+FT EI LK+ TYG H GAFCR+ N+LDLLVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF CND +K++ C+G YI Y E D+ + + KR W N+ NFDNV AM+ LF VSTFEGWP +LYK+IDS +E+ IYN R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S FEYI+FVLI+LNTI LA++ Q + + VMD LNMVFT VFTVE +LKL AF ++YF+DAWN FD +IV+GS +DI VN T + N ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQ+FGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C+P +CD SD YN P CGS+FA YFI+FYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ ++Q NEELR VIKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQ++FR++K+++ E G+ +Q+ + + + I P + CD +D D++P RR +FG +N + G RR S+G ++T+ P
Sbjct: 765 KISELVKKEKITPIPEGSAFFIFSNTNPVRVACHKLINHHIFTNLILVFIMLSSASLAAEDPIRNFSARNIVLGYADYVFTSMFTFEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYIMYKEGDVNQPIIQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNRENMGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLILLNTICLAVQHYGQSELFNYVMDILNMVFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNPTEAPQVDESGNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDH---TQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMPGKLCDPESD------YN---------------------PGEEMT----------------CGSSFAIIYFITFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LEQANEELRAVIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEEGLVGVHPAQNNTAIAL------QAGLRTLHDIGPEIRRAISCDLQDDELVDFIPEEDEEIYRRNGGLFGNHINHIN--GDPRR------SSGHQTNATQRP 1626 HSP 2 Score: 708.368 bits (1827), Expect = 0.000e+0 Identity = 396/718 (55.15%), Postives = 496/718 (69.08%), Query Frame = 1
Query: 943 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSE---------------------GGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVK--------SQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
AQ ++ + S N RPQRALFCL L NP R+ CI +VEWKPF+ IL IFANC ALA P+PE DSN+ N LE +E F++IFT E LKI+A+G +MH AY+RNGWN+LDF+IV+IGL S VL +++ GG DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H++CY D++ + P PC+ + G C + +CK+ W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND++G+ PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E + +E+ + +SE ++ ++ E E G + ++ C P + + R R RL + S FYW+VI+LVFLNT ++SEHY Q +WL Q+ AN + + +FT EML+KMYSLG++ YF +FNRFD FVV I E ++++ + M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQ+FGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD S
Sbjct: 33 AQKKRAQYAKSKKQGSSANTRPQRALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYVPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKEGGEKEEVGENLSAHGHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHASCYFQGTDILEDEPAPCAVN-GHGRTCPINGT-----LCKEG------WQGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGLELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEEEESKRNPSM------PASE---------TESMNTENEKG----EDEKATCCGPTCQKISKSKFSRRWRRWNRLCRRNCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLAMFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVEFEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES 719 HSP 3 Score: 119.398 bits (298), Expect = 6.420e-26 Identity = 105/337 (31.16%), Postives = 160/337 (47.48%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
P P+ A F + NP R C K++ F LIL I + +LAA P R+ + N L + VF +FT E VLK+ +G +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y ND SP C + Y+ D + + W + +FDN +AM+ +F T EGW ++Y DS + IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 777 PIPEGSAFFIFSNTNPVRVACHKLINHHIFTNLILVFIMLSSASLAAEDPI--RNFSARNIVLGYADYVFTSMFTFEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCNDEAKSSPEECKGTYIM-YKEGDVNQPII---------QKRHWHNSDF---NFDNVLMAMMALFTVSTFEGWPALLYKAIDSNRENMGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1092 HSP 4 Score: 95.5153 bits (236), Expect = 9.861e-19 Identity = 72/256 (28.12%), Postives = 124/256 (48.44%), Query Frame = 1
Query: 4237 EEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSF--RYRVW---------WLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
E E N E +K + E A P + I K F R+R W + S PF +++ +L+ LNT++++ + QP QV D N V +FT E L+K+ + G + YF +N FD +V G + I + + I+ FR R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQA+L +F+ TGE W +M
Sbjct: 429 ETESMNTENEKGED---EKATCCGPTCQKISKSKFSRRWRRWNRLCRRNCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLAMFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVEFEIMSP-------LGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKR----STFDNFPQALLTVFQILTGEDWNAVM 670 HSP 5 Score: 89.3521 bits (220), Expect = 7.219e-17 Identity = 68/263 (25.86%), Postives = 139/263 (52.85%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQ--------------TDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMYDGI-------RSYGNLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ VL+ LNT L +HY QS + + N++F +FT+EM++K+ + R YF +N FD +V+ S+++I + + T+ + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R +NF +F Q++L +F+ TGE W E+M + S N G+ S + +Y++ ++ ++++N+F+A+ +DN
Sbjct: 1119 VVNSTGFEYIMFVLILLNTICLAVQHYGQSELFNYVMDILNMVFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNPTEAPQVDESGNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDHTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMPGKLCDPESDYNPGEEMTCGSSFAIIYFITFYMLCAFLIINLFVAVIMDNF 1381 HSP 6 Score: 85.1149 bits (209), Expect = 1.424e-15 Identity = 77/327 (23.55%), Postives = 138/327 (42.20%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-GPDVKA--------------LRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWI----------------NDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEY++ I N LA S N ++ + +VF +FT E VLK++AF P Y + WN D LIV+ ++ +++++ P V R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+ M++ T +N+ N N F F A+L +F+C T E W +IM + G S+ IYF++ ++ +F ++NL + V+ F
Sbjct: 1109 KNPYQYKFWYVVNSTGFEYIMFVLILLNTICLAVQH---YGQSELFNYVMDILNMVFTAVFTVEMVLKLIAF----KPRHYFTDAWNTFDALIVVGSVVDIAITEVNPTEAPQVDESGNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVF-GKI---------AMVD-----HTQINR------------------NNN--------------FQTFPQAVLLLFRCATGEAWQEIMLACMPGKLCDPESDYNPGEEMTCGSSFAIIYFITFYMLCAFLIINLFVAVIMDNF 1381 HSP 7 Score: 77.7962 bits (190), Expect = 2.276e-13 Identity = 62/265 (23.40%), Postives = 116/265 (43.77%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYD------------HVNGTNNNHRGD-RLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-----------GKITTENEKEMKEINRN----------------------NNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
L+ +PF+ I + I N ++LA+ + ++ + F +FT+E LK+ A+G Y + WN+ DF+IV+ ++ + N + + H G + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G E+E +N + NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 74 LVEWKPFDIFILIAIFANCMALAVYVPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKEGGEKEEVGENLSAHGHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHASCYFQGTDILEDEPAPCAVNGHGRTCPINGTLCKEGWQGPNGGITNFDNFMFAMLTVFQCITMEGWTDV-LYWMNDAM 337 HSP 8 Score: 77.0258 bits (188), Expect = 4.456e-13 Identity = 79/299 (26.42%), Postives = 123/299 (41.14%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPI--------------------NNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNK------------REWINNP----LNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
+ F NN R+ C + F +L+ I + LA P D +S N L +Y F +FT+E LK+I YGLV H A+ R+ N+LD ++V+ + S + + ++ LR R LR + G+ + + +K++ ++ + L+ F ++A+IG++LF GK H SC Q E + A VN +E P NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 57 ALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYVPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKEGGEKEEVGENLSAHGHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKM----------HASCYFQGTDILEDEPAPCAVNGHGRTCPINGTLCKEGWQGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGLELPWVY 345
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:ZFIN;Acc:ZDB-GENE-020129-1]) HSP 1 Score: 957.977 bits (2475), Expect = 0.000e+0 Identity = 542/948 (57.17%), Postives = 665/948 (70.15%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTN---------------NNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYL--PSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSP 6084
R +S++ KEK P+P A +FFIF P+NKFR CH I NH F N++L I++SS LAAEDP+ +S RN+IL Y DY+FT +FT+EI LK+ YG H G+FCR+ NILDL+VV S+IS I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GKF C D SK T CRG YI Y + ++ K +R W N+ NFD+V M+ LFAVSTFEGWPG+LY++IDS ED IYN R ++SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++F LI+LNTI LA++ Q Q + + M+ LNM+FTG+FTVE +LKL AF ++YF DAWN FD +IV+GS +DI VN + N + ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI ++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C P+ C+ S+ I+H + CGS+FA YF+SFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT L+IKT+G+ ++Q NEELR ++KKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K KR E+ LSL GP I IS L E + K+ + S RR+ +FG +N + S G ++ P+ + RP+ +++S SP
Sbjct: 872 RPLSDIQLKEKAVPMPQAKAFFIFSPSNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADYVFTGIFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTSLLQFMFACIGVQLFKGKFFYCTDTSKQTQAECRGAYILYKDGNVGKPEKAQRSWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHAEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQSQSFNKAMNILNMLFTGLFTVEMILKLIAFKPRHYFVDAWNTFDALIVVGSVVDIAITEVNPADPSSSPPSSVVRPMGLQNTEDNARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAL---RDNSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSE------------------------------------------INHSSE--DCGSHFAIFYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGN-LEQANEELRAIVKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK-KRKEQGLVAKIPPKTALSLQAGLRTLHDMGPEIRRAISGDLTVEEELERAMKETVCAASEDDIFRRSGGLFGNHVNYYHQ------------SDGHVS----FPQSFTTQRPLHISKSGSP 1754 HSP 2 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 405/691 (58.61%), Postives = 500/691 (72.36%), Query Frame = 1
Query: 982 RSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-----SKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
++ + + RP RAL CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TC+ K + E P PC+ S G C + + C W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + +++G ++ K + S +S + D+ + ++ ET ++ + F SR R+WNR CRR CR VKS FYW+VI LVFLNT + SEH++Q WL + Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F QSLLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S
Sbjct: 102 QASTASTRPPRALLCLTLKNPIRRACINIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLCHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGGTSMGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHRTCFFYKDGHKGHIAEEKPAPCAPSSAHGRHCSPPNIT----QCMMG------WEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDDEGLDDDKPRNLSMPA---SENESVNTDNAPAGDMEGETCCTRMANRISKSKF-----SRYSRRWNRLCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHHQQPEWLTNVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETR--RSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAES 772 HSP 3 Score: 105.145 bits (261), Expect = 1.411e-21 Identity = 99/345 (28.70%), Postives = 160/345 (46.38%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLD-----FLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKD---NKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLI---------IIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
P PQ +A F + N FR C KIV F LILF I + +LAA P ++ + N L + VF IFT E +LK+ A+G +H G++ RN +N+LD ++ G+ S+ ++ VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK + D ++ C G + KD K E ++ S N +FD+ M+ +F T EGW ++Y DS IY ++ II +FF+MN+ +G + F ++ E+ K + K + Q
Sbjct: 885 PMPQAKAFFIFSPSNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPV--KNDSFRNQILGYADYVFTGIFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINV-------VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTSLLQFMFACIGVQLFKGKF----FYCTDTSKQTQAEC---------------RGAYILYKDGNVGKPEKAQRSWENSDF-NFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHAEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQ 1200 HSP 4 Score: 87.8113 bits (216), Expect = 2.508e-16 Identity = 56/203 (27.59%), Postives = 105/203 (51.72%), Query Frame = 1
Query: 4363 ITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
+ S F +++ L+ LNT+++A + +QP+ V D N V +FT E LLK+ + G + YF +N FD +V G ++ I + + I+ R R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E R + F FPQ++L +F+ TGE W ++M
Sbjct: 534 VKSNVFYWLVIFLVFLNTLTIASEHHQQPEWLTNVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSP-------LGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE------TRRSTFDNFPQSLLTVFQILTGEDWNSVM 723 HSP 5 Score: 86.6557 bits (213), Expect = 5.476e-16 Identity = 66/261 (25.29%), Postives = 115/261 (44.06%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVL-GSFIDIIYDHVNGTNNNHRGDRL--ISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF----------------GKITTENEKEMKEINRN-----------------------NNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
++ +PFE II + I N ++LA+ + ++ + +F +FTVE LK+ A+G Y + WN+ DFIIV+ G F I+ G G + + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G I E + + NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 130 IVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLCHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGGTSMGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHRTCFFYKDGHKGHIAEEKPAPCAPSSAHGRHCSPPNITQCMMGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDV-LYWMQDAM 389 HSP 6 Score: 82.0333 bits (201), Expect = 1.378e-14 Identity = 76/334 (22.75%), Postives = 137/334 (41.02%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-----------------------DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYW------------INDS---VGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEYL+ I N LA S + N A+ + ++F +FT E +LK++AF P Y + WN D LIV+ ++ +++++ P + R FRV+R ++L+S ++ ++ + +++ L ++ALL + + IYA+IG+++F GK+ + + N+N +F F A+L +F+C T E W +IM IN S G + YFVS ++ +F ++NL + V+ F
Sbjct: 1217 KNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQH---HGQSQSFNKAMNILNMLFTGLFTVEMILKLIAF----KPRHYFVDAWNTFDALIVVGSVVDIAITEVNPADPSSSPPSSVVRPMGLQNTEDNARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMF-GKI----------------------------------ALRDNSQINRN------------NNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSEINHSSEDCGSHFAIFYFVSFYMLCAFLIINLFVAVIMDNF 1496 HSP 7 Score: 81.6481 bits (200), Expect = 1.864e-14 Identity = 77/280 (27.50%), Postives = 124/280 (44.29%), Query Frame = 1
Query: 3376 NKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVL----TSIISYPINNDAISXXXXXXXXXXXXXXXA------INRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKR--------------EWINNPL-NFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
N R+ C I F I+L+ I + LA P D ++ N L +YLF +FTVE LKVI YGL+ H A+ R+ N+LD ++V+ ++I+ D + + ++ LRA + G+ + + +K++ ++ + L+ F ++A+IG++LF GK K+ H +G A A + R E N+ + NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 121 NPIRRACINIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLCHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGGTSMGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHRTCFFYKDGH---KGHIAEEKPAPCAPSSAHGRHCSPPNITQCMMGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVY 397 HSP 8 Score: 80.4925 bits (197), Expect = 3.649e-14 Identity = 67/270 (24.81%), Postives = 137/270 (50.74%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTD-----------AMPPLG-----------VSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMY----------DGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ L+ LNT L +H+ QS + N N++F LFT+EM++K+ + R YF +N FD +V+ S+++I + + + + P+G ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R +NF +F Q++L +F+ TGE W E+M ++ + S + Y+V ++ ++++N+F+A+ +DN
Sbjct: 1227 VVNSTYFEYLMFTLILLNTICLAMQHHGQSQSFNKAMNILNMLFTGLFTVEMILKLIAFKPRHYFVDAWNTFDALIVVGSVVDIAITEVNPADPSSSPPSSVVRPMGLQNTEDNARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDNSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSEINHSSEDCGSHFAIFYFVSFYMLCAFLIINLFVAVIMDNF 1496
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Zebrafish
Match: cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:ZFIN;Acc:ZDB-GENE-020129-1]) HSP 1 Score: 952.584 bits (2461), Expect = 0.000e+0 Identity = 546/977 (55.89%), Postives = 667/977 (68.27%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVN--------------------------------------------GTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYL--PSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSP 6084
R +S++ KEK P+P A +FFIF P+NKFR CH I NH F N++L I++SS LAAEDP+ +S RN+IL Y DY+FT +FT+EI LK+ YG H G+FCR+ NILDL+VV S+IS I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GKF C D SK T CRG YI Y + ++ K +R W N+ NFD+V M+ LFAVSTFEGWPG+LY++IDS ED IYN R ++SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++F LI+LNTI LA++ Q Q + + M+ LNM+FTG+FTVE +LKL AF + YFSD WNVFDF+IV+GS ID+I +N G N R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI ++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C P+ C+ S+ I+H + CGS+FA YF+SFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT L+IKT+G+ ++Q NEELR ++KKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K KR E+ LSL GP I IS L E + K+ + S RR+ +FG +N + S G ++ P+ + RP+ +++S SP
Sbjct: 872 RPLSDIQLKEKAVPMPQAKAFFIFSPSNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADYVFTGIFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTSLLQFMFACIGVQLFKGKFFYCTDTSKQTQAECRGAYILYKDGNVGKPEKAQRSWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHAEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQSQSFNKAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINHYFVDAWNTFDALIVVGSVVDIAITEVNPADPSSSPPSSVVRPMGLQNTEDNAR-ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAL---RDNSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSE------------------------------------------INHSSE--DCGSHFAIFYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGN-LEQANEELRAIVKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK-KRKEQGLVAKIPPKTALSLQAGLRTLHDMGPEIRRAISGDLTVEEELERAMKETVCAASEDDIFRRSGGLFGNHVNYYHQ------------SDGHVS----FPQSFTTQRPLHISKSGSP 1782 HSP 2 Score: 719.153 bits (1855), Expect = 0.000e+0 Identity = 405/691 (58.61%), Postives = 500/691 (72.36%), Query Frame = 1
Query: 982 RSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-----SKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
++ + + RP RAL CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TC+ K + E P PC+ S G C + + C W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + +++G ++ K + S +S + D+ + ++ ET ++ + F SR R+WNR CRR CR VKS FYW+VI LVFLNT + SEH++Q WL + Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F QSLLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S
Sbjct: 102 QASTASTRPPRALLCLTLKNPIRRACINIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLCHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGGTSMGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHRTCFFYKDGHKGHIAEEKPAPCAPSSAHGRHCSPPNIT----QCMMG------WEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDDEGLDDDKPRNLSMPA---SENESVNTDNAPAGDMEGETCCTRMANRISKSKF-----SRYSRRWNRLCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHHQQPEWLTNVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETR--RSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAES 772 HSP 3 Score: 104.76 bits (260), Expect = 1.620e-21 Identity = 99/345 (28.70%), Postives = 160/345 (46.38%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLD-----FLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKD---NKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLI---------IIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
P PQ +A F + N FR C KIV F LILF I + +LAA P ++ + N L + VF IFT E +LK+ A+G +H G++ RN +N+LD ++ G+ S+ ++ VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK + D ++ C G + KD K E ++ S N +FD+ M+ +F T EGW ++Y DS IY ++ II +FF+MN+ +G + F ++ E+ K + K + Q
Sbjct: 885 PMPQAKAFFIFSPSNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPV--KNDSFRNQILGYADYVFTGIFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINV-------VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTSLLQFMFACIGVQLFKGKF----FYCTDTSKQTQAEC---------------RGAYILYKDGNVGKPEKAQRSWENSDF-NFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHAEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQ 1200 HSP 4 Score: 87.4261 bits (215), Expect = 2.876e-16 Identity = 56/203 (27.59%), Postives = 105/203 (51.72%), Query Frame = 1
Query: 4363 ITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
+ S F +++ L+ LNT+++A + +QP+ V D N V +FT E LLK+ + G + YF +N FD +V G ++ I + + I+ R R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E R + F FPQ++L +F+ TGE W ++M
Sbjct: 534 VKSNVFYWLVIFLVFLNTLTIASEHHQQPEWLTNVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSP-------LGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE------TRRSTFDNFPQSLLTVFQILTGEDWNSVM 723 HSP 5 Score: 86.2705 bits (212), Expect = 6.495e-16 Identity = 66/261 (25.29%), Postives = 115/261 (44.06%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVL-GSFIDIIYDHVNGTNNNHRGDRL--ISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF----------------GKITTENEKEMKEINRN-----------------------NNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
++ +PFE II + I N ++LA+ + ++ + +F +FTVE LK+ A+G Y + WN+ DFIIV+ G F I+ G G + + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G I E + + NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 130 IVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLCHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGGTSMGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHRTCFFYKDGHKGHIAEEKPAPCAPSSAHGRHCSPPNITQCMMGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDV-LYWMQDAM 389 HSP 6 Score: 81.2629 bits (199), Expect = 2.210e-14 Identity = 77/280 (27.50%), Postives = 124/280 (44.29%), Query Frame = 1
Query: 3376 NKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVL----TSIISYPINNDAISXXXXXXXXXXXXXXXA------INRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKR--------------EWINNPL-NFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
N R+ C I F I+L+ I + LA P D ++ N L +YLF +FTVE LKVI YGL+ H A+ R+ N+LD ++V+ ++I+ D + + ++ LRA + G+ + + +K++ ++ + L+ F ++A+IG++LF GK K+ H +G A A + R E N+ + NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 121 NPIRRACINIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLCHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGGTSMGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHRTCFFYKDGH---KGHIAEEKPAPCAPSSAHGRHCSPPNITQCMMGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVY 397 HSP 7 Score: 80.8777 bits (198), Expect = 2.726e-14 Identity = 82/362 (22.65%), Postives = 141/362 (38.95%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-------------------------SEGGP--------------------------DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYW------------INDS---VGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEYL+ I N LA S + N A+ + ++F +FT E +LK++AF P Y + WN+ DFLIVI +I +LS++ +E P + R FRV+R ++L+S ++ ++ + +++ L ++ALL + + IYA+IG+++F GK+ + + N+N +F F A+L +F+C T E W +IM IN S G + YFVS ++ +F ++NL + V+ F
Sbjct: 1217 KNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQH---HGQSQSFNKAMNILNMLFTGLFTVEMILKLIAF----KPRGYFSDPWNVFDFLIVIGSIIDVILSEINHYFVDAWNTFDALIVVGSVVDIAITEVNPADPSSSPPSSVVRPMGLQNTEDNARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMF-GKI----------------------------------ALRDNSQINRN------------NNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSEINHSSEDCGSHFAIFYFVSFYMLCAFLIINLFVAVIMDNF 1524 HSP 8 Score: 70.4774 bits (171), Expect = 4.680e-11 Identity = 71/298 (23.83%), Postives = 140/298 (46.98%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQ--------------------------TDAMP-------------PLG-----------VSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSN-FDSFVQSLLTVFQILTGEDWNEVMY----------DGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ L+ LNT L +H+ QS + N N++F LFT+EM++K+ + R YF +N FDF +VI SI+++++ + T+ P P+G ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R+N F +F Q++L +F+ TGE W E+M ++ + S + Y+V ++ ++++N+F+A+ +DN
Sbjct: 1227 VVNSTYFEYLMFTLILLNTICLAMQHHGQSQSFNKAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINHYFVDAWNTFDALIVVGSVVDIAITEVNPADPSSSPPSSVVRPMGLQNTEDNARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDNSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSEINHSSEDCGSHFAIFYFVSFYMLCAFLIINLFVAVIMDNF 1524
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1663.66 bits (4307), Expect = 0.000e+0 Identity = 979/1778 (55.06%), Postives = 1208/1778 (67.94%), Query Frame = 1
Query: 916 LNLAALTLSAQIASGGRKRTPARSQ-----SGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY----SKNDVMMES-PVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGG---AHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXP-TNVDGEEAKACNSS---NVSPNIDEKTRFTDAERLIKSEEM--NGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRR-VSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNG--TNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYLPSHLGAE--RRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSK-------SPTNHPPVKLTLAP 6120
+ AA + ++S RKR Q + RP RAL CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++ G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TCY DV+ E P PC+ N G C + +C+ S W GP GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G P +YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E++ + K + +SE D + E G AH + ++ SR R+WNR CRR CR VKS FYW+VI LVFLNT + SEHY Q WL Q+TAN + + LFT EML+KMYSLG++ YF +FNRFD F+V ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S +K+E E +E + E K N S + P ++E + + + E N I+ E T + E +EE+E R +SE+ KEK P+P AS+FF+F +N+FR CH I N+ F N++L I++SS LAAEDP+ S RN++L YFD +FT++FTVEI LK+ YG H G+FCR+ NILDLLVV S+IS+ I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GK SC D SK T C+G+YI Y + D+++ + R W N+ +FDNV +AM+ LF VSTFEGWP +LY++IDS ED IYN+R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++FVLI+LNTI LA++ Q +++ M+ LNM+FTG+FTVE +LKL AF K YFSD WNVFDF+IV+GS +D+I N + N + ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQ+FGKI + EINRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP C S+ + KCGS+FA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT+L IKTDG+ ++Q NEELR +IKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K+++ + G SQ LSL GP I IS L E D+ K+ + + + RR +FG + Q S R + P+ + RP+ +N++ SP++ V T P
Sbjct: 72 MGAAANATISTVSSTQRKRQQYSKQKKQGTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYLTNGYPDVLTEEEPSPCALESNNGRHCPN------GTLCR------SGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDIDEEKPRNMSM----PTSETESVNTDNVGSGDVEEESCGVRLAHRISKSKF-------SRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPVPAVEENKEKIELKAITADGESPPNTKISVEEFSTNENEEKTPYPSSNETPGEEEEEEPEMPVGPRPRPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQVLFYFDIVFTAIFTVEIVLKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQYQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCSFKEAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSVVDVILSETNVSISGQNVEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAL---NDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESETSEE----------------------------------------------KCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIKTDGN-LEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKP-SQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVGYYQ---SEVRSA--------------FPQTFTTQRPLHINKTSGGPGDLDSPSHEKLVDSTFTP 1758
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1654.03 bits (4282), Expect = 0.000e+0 Identity = 978/1792 (54.58%), Postives = 1209/1792 (67.47%), Query Frame = 1
Query: 916 LNLAALTLSAQIASGGRKRTPARSQ-----SGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY----SKNDVMMES-PVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGG---AHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXP-TNVDGEEAKACNSS---NVSPNIDEKTRFTDAERLIKSEEM--NGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRR-VSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTN---NNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGST-------------VDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYLPSHLGAE--RRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSK-------SPTNHPPVKLTLAP 6120
+ AA + ++S RKR Q + RP RAL CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++ G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TCY DV+ E P PC+ N G C + +C+ S W GP GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G P +YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E++ + K + +SE D + E G AH + ++ SR R+WNR CRR CR VKS FYW+VI LVFLNT + SEHY Q WL Q+TAN + + LFT EML+KMYSLG++ YF +FNRFD F+V ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S +K+E E +E + E K N S + P ++E + + + E N I+ E T + E +EE+E R +SE+ KEK P+P AS+FF+F +N+FR CH I N+ F N++L I++SS LAAEDP+ S RN+IL DY+FTS+FT+EI LK+ YG H G+FCR+ NILDLLVV S+IS+ I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GK SC D SK T C+G+YI Y + D+++ + R W N+ +FDNV +AM+ LF VSTFEGWP +LY++IDS ED IYN+R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++FVLI+LNTI LA++ Q +++ M+ LNM+FTG+FTVE +LKL AF K+YF DAWN FD +IV+GS +DI +N +N +N + ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQ+FGKI + EINRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP C S+ + KCGS+FA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT+L IKTDG++ ++Q NEELR +IKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K+++ + G SQ LSL GP I IS L E D+ K+ + + + RR +FG + Q S R + P+ + RP+ +N++ SP++ V T P
Sbjct: 71 MGAAANATISTVSSTQRKRQQYSKQKKQGTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYLTNGYPDVLTEEEPSPCALESNNGRHCPN------GTLCR------SGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDIDEEKPRNMSM----PTSETESVNTDNVGSGDVEEESCGVRLAHRISKSKF-------SRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPVPAVEENKEKIELKAITADGESPPNTKISVEEFSTNENEEKTPYPSSNETPGEEEEEEPEMPVGPRPRPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQYQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCSFKEAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITELNVSNPRLSNVEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAL---NDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESETSEE----------------------------------------------KCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIKTDGNSLLLLFACQIFSWNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKP-SQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVGYYQ---SEVRSA--------------FPQTFTTQRPLHINKTSGGPGDLDSPSHEKLVDSTFTP 1772
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1653.65 bits (4281), Expect = 0.000e+0 Identity = 976/1790 (54.53%), Postives = 1209/1790 (67.54%), Query Frame = 1
Query: 916 LNLAALTLSAQIASGGRKRTPARSQ-----SGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY----SKNDVMMES-PVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGG---AHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNL--ADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSP---------NIDEKTRFTDAER----LIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTN------NNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYLPSHLGAE--RRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSK-------SPTNHPPVKLTLAP 6120
+ AA + ++S RKR Q + RP RAL CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++ G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TCY DV+ E P PC+ N G C + +C+ S W GP GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G P +YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E++ + K + +SE D + E G AH + ++ SR R+WNR CRR CR VKS FYW+VI LVFLNT + SEHY Q WL Q+TAN + + LFT EML+KMYSLG++ YF +FNRFD F+V ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNL A++ + ++E++E + + E+ + S SP I+ K D E I EE + + +E S+ +E +EE R +SE+ KEK P+P AS+FF+F +N+FR CH I N+ F N++L I++SS LAAEDP+ S RN++L YFD +FT++FTVEI LK+ YG H G+FCR+ NILDLLVV S+IS+ I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GK SC D SK T C+G+YI Y + D+++ + R W N+ +FDNV +AM+ LF VSTFEGWP +LY++IDS ED IYN+R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++FVLI+LNTI LA++ Q +++ M+ LNM+FTG+FTVE +LKL AF K+YF DAWN FD +IV+GS +DI +N +N N R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQ+FGKI + EINRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP C S+ + KCGS+FA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT+L IKTDG+ ++Q NEELR +IKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K+++ + G SQ LSL GP I IS L E D+ K+ + + + RR +FG + Q S R + P+ + RP+ +N++ SP++ V T P
Sbjct: 106 MGAAANATISTVSSTQRKRQQYSKQKKQGTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYLTNGYPDVLTEEEPSPCALESNNGRHCPN------GTLCR------SGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDIDEEKPRNMSM----PTSETESVNTDNVGSGDVEEESCGVRLAHRISKSKF-------SRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPVPAVEENKEKIELKAITADGESPPNTKISVEEFSTNENEEKTPYPSSNETPGEEEEEEPEMPVGPRP--------RPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQVLFYFDIVFTAIFTVEIVLKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQYQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCSFKEAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITELNVSNPRLSVTENSR----ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAL---NDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESETSEE----------------------------------------------KCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIKTDGN-LEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKP-SQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVGYYQ---SEVRSA--------------FPQTFTTQRPLHINKTSGGPGDLDSPSHEKLVDSTFTP 1792
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1652.88 bits (4279), Expect = 0.000e+0 Identity = 982/1807 (54.34%), Postives = 1209/1807 (66.91%), Query Frame = 1
Query: 916 LNLAALTLSAQIASGGRKRTPARSQ-----SGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY----SKNDVMMES-PVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGG---AHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXP-TNVDGEEAKACNSS---NVSPNIDEKTRFTDAERLIKSEEM--NGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRR-VSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNG-----------------------TNNNHRGDRL--------ISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYLPSHLGAE--RRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSK-------SPTNHPPVKLTLAP 6120
+ AA + ++S RKR Q + RP RAL CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++ G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TCY DV+ E P PC+ N G C + +C+ S W GP GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G P +YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E++ + K + +SE D + E G AH + ++ SR R+WNR CRR CR VKS FYW+VI LVFLNT + SEHY Q WL Q+TAN + + LFT EML+KMYSLG++ YF +FNRFD F+V ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S +K+E E +E + E K N S + P ++E + + + E N I+ E T + E +EE+E R +SE+ KEK P+P AS+FF+F +N+FR CH I N+ F N++L I++SS LAAEDP+ S RN++L YFD +FT++FTVEI LK+ YG H G+FCR+ NILDLLVV S+IS+ I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GK SC D SK T C+G+YI Y + D+++ + R W N+ +FDNV +AM+ LF VSTFEGWP +LY++IDS ED IYN+R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++FVLI+LNTI LA++ Q +++ M+ LNM+FTG+FTVE +LKL AF K YFSD WNVFDF+IV+GS +D+I N T N RL ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQ+FGKI + EINRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP C S+ + KCGS+FA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT+L IKTDG+ ++Q NEELR +IKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K+++ + G SQ LSL GP I IS L E D+ K+ + + + RR +FG + Q S R + P+ + RP+ +N++ SP++ V T P
Sbjct: 71 MGAAANATISTVSSTQRKRQQYSKQKKQGTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYLTNGYPDVLTEEEPSPCALESNNGRHCPN------GTLCR------SGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDIDEEKPRNMSM----PTSETESVNTDNVGSGDVEEESCGVRLAHRISKSKF-------SRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPVPAVEENKEKIELKAITADGESPPNTKISVEEFSTNENEEKTPYPSSNETPGEEEEEEPEMPVGPRPRPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQVLFYFDIVFTAIFTVEIVLKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQYQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCSFKEAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSVVDVILSETNHYFCDAWNTFDALIVVGSIVDIAITELNVSNPRLSNVEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAL---NDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESETSEE----------------------------------------------KCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIKTDGN-LEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKP-SQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVGYYQ---SEVRSA--------------FPQTFTTQRPLHINKTSGGPGDLDSPSHEKLVDSTFTP 1786
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1644.02 bits (4256), Expect = 0.000e+0 Identity = 983/1827 (53.80%), Postives = 1210/1827 (66.23%), Query Frame = 1
Query: 916 LNLAALTLSAQIASGGRKRTPARSQ-----SGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY----SKNDVMMES-PVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGG---AHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXP-TNVDGEEAKACNSS---NVSPNIDEKTRFTDAERLIKSEEM--NGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRR-VSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYF--------------------DYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNG-----------------------TNNNHRGDRL--------ISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYLPSHLGAE--RRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSK-------SPTNHPPVKLTLAP 6120
+ AA + ++S RKR Q + RP RAL CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++ G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TCY DV+ E P PC+ N G C + +C+ S W GP GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G P +YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E++ + K + +SE D + E G AH + ++ SR R+WNR CRR CR VKS FYW+VI LVFLNT + SEHY Q WL Q+TAN + + LFT EML+KMYSLG++ YF +FNRFD F+V ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S +K+E E +E + E K N S + P ++E + + + E N I+ E T + E +EE+E R +SE+ KEK P+P AS+FF+F +N+FR CH I N+ F N++L I++SS LAAEDP+ S RN++L YF DY+FTS+FT+EI LK+ YG H G+FCR+ NILDLLVV S+IS+ I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GK SC D SK T C+G+YI Y + D+++ + R W N+ +FDNV +AM+ LF VSTFEGWP +LY++IDS ED IYN+R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++FVLI+LNTI LA++ Q +++ M+ LNM+FTG+FTVE +LKL AF K YFSD WNVFDF+IV+GS +D+I N T N RL ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQ+FGKI + EINRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP C S+ + KCGS+FA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT+L IKTDG+ ++Q NEELR +IKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K+++ + G SQ LSL GP I IS L E D+ K+ + + + RR +FG + Q S R + P+ + RP+ +N++ SP++ V T P
Sbjct: 71 MGAAANATISTVSSTQRKRQQYSKQKKQGTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYLTNGYPDVLTEEEPSPCALESNNGRHCPN------GTLCR------SGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDIDEEKPRNMSM----PTSETESVNTDNVGSGDVEEESCGVRLAHRISKSKF-------SRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPVPAVEENKEKIELKAITADGESPPNTKISVEEFSTNENEEKTPYPSSNETPGEEEEEEPEMPVGPRPRPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQVLFYFDIVFTAIFTVEIVLKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQYQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCSFKEAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSVVDVILSETNHYFCDAWNTFDALIVVGSIVDIAITELNVSNPRLSNVEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAL---NDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESETSEE----------------------------------------------KCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIKTDGN-LEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKP-SQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVGYYQ---SEVRSA--------------FPQTFTTQRPLHINKTSGGPGDLDSPSHEKLVDSTFTP 1806
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1s (calcium channel, voltage-dependent, L type, alpha 1S subunit [Source:MGI Symbol;Acc:MGI:88294]) HSP 1 Score: 1649.03 bits (4269), Expect = 0.000e+0 Identity = 929/1702 (54.58%), Postives = 1169/1702 (68.68%), Query Frame = 1
Query: 955 SGGRKRTPARSQSGN-PRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----------SEG-GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMM----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNET-SRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGK----ENGK--ESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNG--DIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQ---TSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGS 5970
G RK+ P + PRP RALFCLTL+NP RK CI IVEWKPFE +IL TIFANC ALA P PE D+NT+N LEK+E F+++F+ E +KI+A+GF+ H AYLR+GWN+LDF+IV +G+ + +L ++ S+G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI +AM+PLFHIALL LF++IIYAIIGLELF GK+H TCY D++ E P PC+ +G C N +E W GPN GIT FDNFG +MLTV+QCI+MEGWT ++YW+ND++G WPWIYFV+LI++GSFF++NLVLGVLSGEF+KEREKAK RG +QK RE+ Q +ED++GY+ WI E + D+ +GK E G ES +++ GL K + H +Q VF + LVKS+ FYW+VI++V LNT + SEH+ Q +WL Q+ AN + + LFT+EML+KMY LG+R YF +FNRFD FVV ILEI+++++ AM PLG+SVLRC RLLR+FK+T+YW+SL NLV SLL S++SI SLL+LLFLFI+IF+LLGMQLFGG+++F+ RSNFD+F Q+L++VFQ+LTGEDWN VMY+GI +YG +L C+Y++ILF+CGNYILLNVFLAIAVDNLA+ S EE K S P+ E+ R T ++L + + G A + + + ++ K+ +++E+ + + R ++E+ KEK PIP ASSFFIF P NK R CH I N F N +L+ I++SSA LAAEDP+ A+S RN+IL YFDY+FT+VFTVEI LK+ TYG H G+FCR+ NILDLLVV S+IS + + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI+LVT LL+FMFA IGVQLF GKF SCND+SK T CRG Y Y + D ++ + R+WI+N +FDNV +AM++LF VSTFEGWP +LYK+IDS +ED +YNNR ++IF+I YII+IAFFM+NIFVGFVIVTFQ++GE EYKNCELDKNQR+C+++ALKA+P+R YIPK ++Y+VW+++TS FEY++F LIMLNTI L ++ Q ++ + D LN+ FT +FT+E +LKL AF + YF D WNVFDF+IV+GS ID+I ++ + + R IS FFRLFRVMRLVKLL+R EG+RTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ I+L C +CD SD E + CG+NFAY YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF +W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK+CPHR AC LV MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IKKIWKRTS K+LDQV+PP G+D+VTVGKFYATFLIQE FR++ KR EE G + RT + P I +T E E+ G RRT +FG + N L+R S
Sbjct: 9 EGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTVILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCA-------------RTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFI-------------------RHWRQWNRVFRWKCHD----------------LVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSA------------QKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDESAR----ISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHT-------------------------------------------CGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNS 1598
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1s (calcium channel, voltage-dependent, L type, alpha 1S subunit [Source:MGI Symbol;Acc:MGI:88294]) HSP 1 Score: 1640.17 bits (4246), Expect = 0.000e+0 Identity = 929/1717 (54.11%), Postives = 1168/1717 (68.03%), Query Frame = 1
Query: 955 SGGRKRTPARSQSGN-PRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----------SEG-GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMM----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNET-SRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGK----ENGK--ESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNG--DIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQ---TSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNG---------------TNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGS 5970
G RK+ P + PRP RALFCLTL+NP RK CI IVEWKPFE +IL TIFANC ALA P PE D+NT+N LEK+E F+++F+ E +KI+A+GF+ H AYLR+GWN+LDF+IV +G+ + +L ++ S+G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI +AM+PLFHIALL LF++IIYAIIGLELF GK+H TCY D++ E P PC+ +G C N +E W GPN GIT FDNFG +MLTV+QCI+MEGWT ++YW+ND++G WPWIYFV+LI++GSFF++NLVLGVLSGEF+KEREKAK RG +QK RE+ Q +ED++GY+ WI E + D+ +GK E G ES +++ GL K + H +Q VF + LVKS+ FYW+VI++V LNT + SEH+ Q +WL Q+ AN + + LFT+EML+KMY LG+R YF +FNRFD FVV ILEI+++++ AM PLG+SVLRC RLLR+FK+T+YW+SL NLV SLL S++SI SLL+LLFLFI+IF+LLGMQLFGG+++F+ RSNFD+F Q+L++VFQ+LTGEDWN VMY+GI +YG +L C+Y++ILF+CGNYILLNVFLAIAVDNLA+ S EE K S P+ E+ R T ++L + + G A + + + ++ K+ +++E+ + + R ++E+ KEK PIP ASSFFIF P NK R CH I N F N +L+ I++SSA LAAEDP+ A+S RN+IL YFDY+FT+VFTVEI LK+ TYG H G+FCR+ NILDLLVV S+IS + + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI+LVT LL+FMFA IGVQLF GKF SCND+SK T CRG Y Y + D ++ + R+WI+N +FDNV +AM++LF VSTFEGWP +LYK+IDS +ED +YNNR ++IF+I YII+IAFFM+NIFVGFVIVTFQ++GE EYKNCELDKNQR+C+++ALKA+P+R YIPK ++Y+VW+++TS FEY++F LIMLNTI L ++ Q ++ + D LN+ FT +FT+E +LKL AF + YF D WNVFDF+IV+GS ID+I ++ N + IS FFRLFRVMRLVKLL+R EG+RTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ I+L C +CD SD E + CG+NFAY YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF +W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK+CPHR AC LV MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IKKIWKRTS K+LDQV+PP G+D+VTVGKFYATFLIQE FR++ KR EE G + RT + P I +T E E+ G RRT +FG + N L+R S
Sbjct: 9 EGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTVILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCA-------------RTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFI-------------------RHWRQWNRVFRWKCHD----------------LVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSA------------QKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHT-------------------------------------------CGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNS 1617
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1s (calcium channel, voltage-dependent, L type, alpha 1S subunit [Source:MGI Symbol;Acc:MGI:88294]) HSP 1 Score: 1640.17 bits (4246), Expect = 0.000e+0 Identity = 929/1717 (54.11%), Postives = 1168/1717 (68.03%), Query Frame = 1
Query: 955 SGGRKRTPARSQSGN-PRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----------SEG-GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMM----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNET-SRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGK----ENGK--ESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNG--DIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQ---TSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNG---------------TNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGS 5970
G RK+ P + PRP RALFCLTL+NP RK CI IVEWKPFE +IL TIFANC ALA P PE D+NT+N LEK+E F+++F+ E +KI+A+GF+ H AYLR+GWN+LDF+IV +G+ + +L ++ S+G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI +AM+PLFHIALL LF++IIYAIIGLELF GK+H TCY D++ E P PC+ +G C N +E W GPN GIT FDNFG +MLTV+QCI+MEGWT ++YW+ND++G WPWIYFV+LI++GSFF++NLVLGVLSGEF+KEREKAK RG +QK RE+ Q +ED++GY+ WI E + D+ +GK E G ES +++ GL K + H +Q VF + LVKS+ FYW+VI++V LNT + SEH+ Q +WL Q+ AN + + LFT+EML+KMY LG+R YF +FNRFD FVV ILEI+++++ AM PLG+SVLRC RLLR+FK+T+YW+SL NLV SLL S++SI SLL+LLFLFI+IF+LLGMQLFGG+++F+ RSNFD+F Q+L++VFQ+LTGEDWN VMY+GI +YG +L C+Y++ILF+CGNYILLNVFLAIAVDNLA+ S EE K S P+ E+ R T ++L + + G A + + + ++ K+ +++E+ + + R ++E+ KEK PIP ASSFFIF P NK R CH I N F N +L+ I++SSA LAAEDP+ A+S RN+IL YFDY+FT+VFTVEI LK+ TYG H G+FCR+ NILDLLVV S+IS + + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI+LVT LL+FMFA IGVQLF GKF SCND+SK T CRG Y Y + D ++ + R+WI+N +FDNV +AM++LF VSTFEGWP +LYK+IDS +ED +YNNR ++IF+I YII+IAFFM+NIFVGFVIVTFQ++GE EYKNCELDKNQR+C+++ALKA+P+R YIPK ++Y+VW+++TS FEY++F LIMLNTI L ++ Q ++ + D LN+ FT +FT+E +LKL AF + YF D WNVFDF+IV+GS ID+I ++ N + IS FFRLFRVMRLVKLL+R EG+RTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ I+L C +CD SD E + CG+NFAY YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF +W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK+CPHR AC LV MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IKKIWKRTS K+LDQV+PP G+D+VTVGKFYATFLIQE FR++ KR EE G + RT + P I +T E E+ G RRT +FG + N L+R S
Sbjct: 9 EGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTVILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCA-------------RTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFI-------------------RHWRQWNRVFRWKCHD----------------LVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSA------------QKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHT-------------------------------------------CGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNS 1617
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1s (calcium channel, voltage-dependent, L type, alpha 1S subunit [Source:MGI Symbol;Acc:MGI:88294]) HSP 1 Score: 1382.08 bits (3576), Expect = 0.000e+0 Identity = 789/1444 (54.64%), Postives = 993/1444 (68.77%), Query Frame = 1
Query: 1675 CKDNKNET-SRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGK----ENGK--ESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNG--DIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQ---TSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGS 5970
C N +E W GPN GIT FDNFG +MLTV+QCI+MEGWT ++YW+ND++G WPWIYFV+LI++GSFF++NLVLGVLSGEF+KEREKAK RG +QK RE+ Q +ED++GY+ WI E + D+ +GK E G ES +++ GL K + H +Q VF + LVKS+ FYW+VI++V LNT + SEH+ Q +WL Q+ AN + + LFT+EML+KMY LG+R YF +FNRFD FVV ILEI+++++ AM PLG+SVLRC RLLR+FK+T+YW+SL NLV SLL S++SI SLL+LLFLFI+IF+LLGMQLFGG+++F+ RSNFD+F Q+L++VFQ+LTGEDWN VMY+GI +YG +L C+Y++ILF+CGNYILLNVFLAIAVDNLA+ S EE K S P+ E+ R T ++L + + G A + + + ++ K+ +++E+ + + R ++E+ KEK PIP ASSFFIF P NK R CH I N F N +L+ I++SSA LAAEDP+ A+S RN+IL YFDY+FT+VFTVEI LK+ TYG H G+FCR+ NILDLLVV S+IS + + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI+LVT LL+FMFA IGVQLF GKF SCND+SK T CRG Y Y + D ++ + R+WI+N +FDNV +AM++LF VSTFEGWP +LYK+IDS +ED +YNNR ++IF+I YII+IAFFM+NIFVGFVIVTFQ++GE EYKNCELDKNQR+C+++ALKA+P+R YIPK ++Y+VW+++TS FEY++F LIMLNTI L ++ Q ++ + D LN+ FT +FT+E +LKL AF + YF D WNVFDF+IV+GS ID+I ++ + + R IS FFRLFRVMRLVKLL+R EG+RTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ I+L C +CD SD E + CG+NFAY YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF +W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK+CPHR AC LV MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IKKIWKRTS K+LDQV+PP G+D+VTVGKFYATFLIQE FR++ KR EE G + RT + P I +T E E+ G RRT +FG + N L+R S
Sbjct: 7 CTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFI-------------------RHWRQWNRVFRWKCHD----------------LVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSA------------QKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDESAR----ISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHT-------------------------------------------CGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNS 1351 HSP 2 Score: 124.405 bits (311), Expect = 1.919e-27 Identity = 93/279 (33.33%), Postives = 135/279 (48.39%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITS---FDNFGLAMLTVFQCITMEGWTQIMYWINDS 1824
P P+ + F + N R C +IV F IL I + ALAA P R + N LE + VF +FT E VLK+ +G +H G++ RN +N+LD L+V + LIS L S VK LR RVLRPLR ++ L+ V+ + A+ + +I L+ + ++A IG++LF GK YS ND+ + C G+ Y+ KD + T P I + FDN AM+++F T EGW Q++Y DS
Sbjct: 525 PIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPI--RADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLE--SSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKF----YSCNDLSKMTEEEC---------------RGYYYIYKDG-DPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDS 779 HSP 3 Score: 99.3673 bits (246), Expect = 7.835e-20 Identity = 83/326 (25.46%), Postives = 146/326 (44.79%), Query Frame = 1
Query: 1012 RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKA------LRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWIN----------------DSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
R L C +NP++ +V FEYL+ I N L S +N + + + F +IFT E VLK++AF P Y + WN+ DFLIVI +I +LS++ + PD A R FRV+R ++L++ ++ ++ + +++ L ++ALL + + IYA+IG+++F GK+ M++ T +N+ N N F F A+L +F+C T E W +I+ + + G ++ + YF+S ++ +F ++NL + V+ F
Sbjct: 849 RPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQH---YNQSEQMNHISDILNVAFTIIFTLEMVLKLIAF----KPRGYFGDPWNVFDFLIVIGSIIDVILSEIDD--PDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMF-GKI---------AMVD-----GTQINR------------------NNN--------------FQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHTCGTNFAYYYFISFYMLCAFLIINLFVAVIMDNF 1118 HSP 4 Score: 58.5362 bits (140), Expect = 1.670e-7 Identity = 73/324 (22.53%), Postives = 138/324 (42.59%), Query Frame = 1
Query: 1045 FRKFCIKIVEWKPFEYLILFTIFANCCALAA---NTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMY-WINDSVGMSWP----WIYFVSLIIIGSFFVMNLVLGVLSGEFSKERE--KAKKRGKYQKAREQM 1983
FR C +V+ K F +L++ + N ++A+ N P + + V + +FT E ++K+ G Y + +N D +V G++ +L + P + LR R+LR ++ SL ++ S++ ++ + + LL III+A++G++LF G+ DF + E R ++FDNF A+++VFQ +T E W +MY I G ++P IYF+ L + G++ ++N+ L + ++ A+K ++ R +M
Sbjct: 174 FRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPL------WLTHLQDVANRVLLTLFTIEMLMKMYGLGL----RQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRY-----------------------------DFEDT-----------EVRR--------SNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKM 439
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Mouse
Match: Cacna1f (calcium channel, voltage-dependent, alpha 1F subunit [Source:MGI Symbol;Acc:MGI:1859639]) HSP 1 Score: 1179.08 bits (3049), Expect = 0.000e+0 Identity = 677/1160 (58.36%), Postives = 834/1160 (71.90%), Query Frame = 1
Query: 2284 VKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLA--DTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGM 5757
VKS A YW V++LVFLNT + SEH+ Q +WL Q AN + + LFT+EML+K+Y LG Y FNRFD FVV ILE +++ AM PLG+SVLRC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLA D G+ G E SS +P + K E +E+ G ++ + M + E+E +EE E NG + + EV+ KEK+ PIP S+FF N RK CH + +H F +++LV I++SS LAAEDP+ A S RN IL YFDY FTS+FTVEI LK+ +G H G+FCRS N+LDLLVV S+IS+ I++ AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF SC D +K+T C+G ++ Y + D+++ V +R W+N+ NFDNV +AM+ LF VSTFEGWP +LYK+ID+ ED IYN +S+F+I YII+IAFFM+NIFVGFVI+TF+ +GE+EY+NCELDKNQR+C+E+ALKA+P+RRYIPK +YRVW + S FEY++F+LI+LNT++LA++ +Q + MD LNMVFTG+FT+E +LK+ AF K+YF+DAWN FD +IV+GS +DI VN + ++ R ISI FFRLFRVMRLVKLLS+GEGIRTLLWTF+KSFQALPYVALLI M+FFIYAVIGMQMFGK+ ++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML LP CD SD P F CGS+FA YFISF+M+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDP AKGRIKHLDVV LLR+I PPLGFGK CPHR AC LV MN+PLNSDGTV FNATLFALVRT+LKIKT+G+ +DQ N+ELR+VIKKIWKR QK+LD+V+PP ++VTVGKFYATFLIQ++FR++++++ +KG+
Sbjct: 526 VKSNACYWAVLLLVFLNTLTIASEHHGQPLWLTQTQEYANKVLLCLFTVEMLLKLYGLGPSVYVASFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCVYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKD----------------KGRE----KSSEGNPPKENKVLVPGGE----NEDAKGARSEGAAPGMEEEEEEEEEEEEEEEEE------NG-AGHVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKACHTLIHHHIFTSLILVFIILSSVSLAAEDPIRAHSFRNHILGYFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNLLDLLVVSVSLISFGIHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYSCTDEAKHTLKECKGSFLIYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDANAEDEGPIYNYHVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFADAWNTFDALIVVGSVVDIAVTEVNSSEDSSR----ISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESD---------------------------FGPGEEFT----------------CGSSFAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNVPLNSDGTVTFNATLFALVRTSLKIKTEGN-LDQANQELRMVIKKIWKRIKQKLLDEVIPPPDEEEVTVGKFYATFLIQDYFRKFRRRK---EKGL 1600 HSP 2 Score: 456.447 bits (1173), Expect = 1.387e-129 Identity = 226/369 (61.25%), Postives = 269/369 (72.90%), Query Frame = 1
Query: 1003 RPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM------------SEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMM--ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDIS-DDEENDG 2064
R RALFCLTL NP R+ CI IVEWKPF+ LIL TIFANC AL P+PE DSNT N LE++E VF+VIFT E VLKI+A+G ++HP AY+RNGWNLLDF+IV++GL S +L + GG DVKALRAFRVLRPLRLVSG+PSL +V+NSIM+A+VPL HIALL LFVIIIYAIIGLELF G++H TCY M E P PC++S G C H+ C+ RW GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AE++ D DG
Sbjct: 67 RSPRALFCLTLTNPIRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASS-GSGRSCTLNHTE-----CR------GRWPGPNGGITNFDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQMEEDLRGYLDWITQAEELDLHDPSVDG 423 HSP 3 Score: 112.849 bits (281), Expect = 5.873e-24 Identity = 87/279 (31.18%), Postives = 128/279 (45.88%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR---WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDS 1824
P P+ A FCL+ NP RK C ++ F LIL I + +LAA P R + N L + F IFT E +LK+ FG +H G++ R+ +NLLD L+V + LIS S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK +S + E C S Y D R W + +FDN AM+ +F T EGW ++Y D+
Sbjct: 847 PIPEGSAFFCLSQTNPLRKACHTLIHHHIFTSLILVFIILSSVSLAAEDPI--RAHSFRNHILGYFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNLLDLLVVSVSLIS--FGIHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYSCTDEAKHTLKE----CKGSF-------------LIYPDGDVSRPLVRERLWVNSDF---NFDNVLSAMMALFTVSTFEGWPALLYKAIDA 1101 HSP 4 Score: 90.1225 bits (222), Expect = 4.979e-17 Identity = 77/316 (24.37%), Postives = 136/316 (43.04%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPD----VKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWI----------------NDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP + V FEYL+ I N ALA + N A++ + +VF +FT E VLKI+AF P Y + WN D LIV+ ++ +++++ + R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+ ++ G Q N+N +F F A+L +F+C T E W +IM + G S+ +YF+S ++ +F ++NL + V+ F
Sbjct: 1179 KNPHQYRVWATVNSAAFEYLMFLLILLNTVALAMQH---YEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAF----KPKHYFADAWNTFDALIVVGSVVDIAVTEVNSSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMF-GKV--------------------ALQDGTQI--------------NRN------------NNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESDFGPGEEFTCGSSFAIVYFISFFMLCAFLIINLFVAVIMDNF 1440 HSP 5 Score: 88.9669 bits (219), Expect = 1.154e-16 Identity = 65/247 (26.32%), Postives = 118/247 (47.77%), Query Frame = 1
Query: 4234 GEEEYKNCELDKNQRKCIEFALKAKPVRRYI-PKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
G+E+ + + R C+ +K + R + + R R + S + + +L+ LNT+++A + QP Q +Y N V +FTVE LLKL G Y + +N FD +V G ++ V + I+ R R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG ++ K + F TFPQA+L +F+ TGE W +M
Sbjct: 483 GDEDEEEGTMASCTR-CLNKIMKTRICRHFRRANRGLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPLWLTQTQEYANKVLLCLFTVEMLLKLYGLGPSVYVASFFNRFDCFVVCGGILETTLVEVGAMQP-------LGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKR----STFDTFPQALLTVFQILTGEDWNVVM 717 HSP 6 Score: 82.8037 bits (203), Expect = 8.308e-15 Identity = 63/257 (24.51%), Postives = 116/257 (45.14%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNN--HRGDRL--ISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-----------------------------GKITTENEKEMK-----EINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
++ +PF+ +I + I N ++L + + ++ + VF +FTVE +LK+ A+G Y + WN+ DFIIV+ ++ + G + H G + + R FRV+R ++L+S + +L + +K+ L ++ALL++ + IYA+IG+++F G+ T N E + NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 88 IVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRSCTLNHTECRGRWPGPNGGITNFDNFFFAMLTVFQCITMEGWTDV-LYWMQDAM 343 HSP 7 Score: 75.0998 bits (183), Expect = 1.972e-12 Identity = 73/284 (25.70%), Postives = 124/284 (43.66%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPIN------NDAISXXXX-----XXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGKF-QSCNDVSKNTHI---------SCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
+ F N R+ C I F ++L+ I + L P D ++ N L +Y+F +FTVE LK++ YGLV H A+ R+ N+LD ++V+ + S + DA ++ LR R LR + G+ + + +K++ ++ + L+ F ++A+IG++LF G+ ++C + + S G+ N + + I NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 71 ALFCLTLTNPIRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRSCTLNHTECRGRWPGPNGGIT---NFDNFFFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVY 351 HSP 8 Score: 63.929 bits (154), Expect = 4.223e-9 Identity = 73/314 (23.25%), Postives = 133/314 (42.36%), Query Frame = 1
Query: 1045 FRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMY-WINDSVGMSWP----WIYFVSLIIIGSFFVMNLVLGV-----LSGEFSKEREKAKKR 1953
R C + V+ + +L +F N +A+ + E V + +FT E +LK+ G P Y+ + +N D +V G++ T L ++ P + LR R+LR ++ SL ++ S++ +M + + LL III++++G++LF GK F + ++ T R ++FD F A+LTVFQ +T E W +MY I G +P +YF+ L I G++ ++N+ L + SG+ ++K +++
Sbjct: 518 LRARCRRAVKSNACYWAVLLLVFLNTLTIASEH---HGQPLWLTQTQEYANKVLLCLFTVEMLLKLYGLG----PSVYVASFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGK------------------------------------FNF----DQTHTKR--------STFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCVYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKDKGREK 776
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|Q25452|CAC1M_MUSDO (Muscle calcium channel subunit alpha-1 OS=Musca domestica OX=7370 PE=2 SV=1) HSP 1 Score: 1766.51 bits (4574), Expect = 0.000e+0 Identity = 1004/1737 (57.80%), Postives = 1207/1737 (69.49%), Query Frame = 1
Query: 934 TLSAQIASGGRKRTPARSQSGN-----PRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSN-VSPNIDEKTRFTDAERLIKSEEMNGDI----ADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHV------------NGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLP--DAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQR--------VGSTRRDSNASPSTGSINHSTELPRDR 6042
T + + + + TP R+Q RP+RALFCLTL+NP R FCIKIV+ K FEY IL TIFANC ALA TPYP DSN N LEKIE +F+VIFT+ECV+KI+A+GF++H G+YLRNGWN LDF IV+IG+IST LS + + G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AM+PL HIALL LFVIIIYAIIGLELFSGKLH TC N +N D+ H+ G + C W GPN GIT+FDNFGL+MLTVFQCIT+EGWT ++Y I D++G SW WIYFVS++I+G+FFVMNL+LGVLSGEFSKER KAK RG +QK RE+ Q +ED++GYLDWI AEDI D + E+ +++ K ++ H ++ QQ F + + + NRR RR CR+ VKSQAFYW++I+LVFLNTGVL +EHYRQ IWLD FQ NI F+ LFT EM++KMYSLG + YF +FNRFD FVVI SI E+V+ ++ M PLGVSVLRC RLLRVFKVT+YW SL NLV SLL S++SI SLL+LLFLFIVIF LLGMQ+FGG+F F ++ KPRSNFDSF QSLLTVFQILTGEDWN VMYDGIR+YG + +++C+YY+ILFICGNYILLNVFLAIAVDNLAD S + ++ E+ N + ++ + + + + E D+ DE S +T + +S RR + K IP +SFFIF N+FR FCH +CNH +FGN +L CIM SSAMLAAE+PL A++SRN +LN FDY FT+VFT+E+ LK+I+YG V H+GAFCRS+ N+LDLLVV S+IS N++AISVVKILRVLRVLRPLRAINRAKGLK VVQCV+VAVK+IGNI+LVT LL+FMFAVIGVQLF GKF SC+D SK C G Y++Y DI K + +REW NN +FD+V AMLTLF VSTFEGWP +LY SIDS KE+ IYN RPIV+ +YI YII+IAFFM+NIFVGFVIVTFQ EGE+EYKNCELDKNQR CIEFALKAKPVRRYIPK S +Y+VWW +TS FEY IFVLIM+NT++LA+KF KQP+ Y +++D LNM+FT VF++EF+ KLAAF FKNYF DAWN FDFIIVLGSFIDI+Y + N G LISINFFRLFRVMRLVKLLS+GEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQ+FGKI E E I+RNNNFQTFPQA+LVLFRSATGEAWQ IM+ C P D CD SD V CGS+ A+PYFISFY++CSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF+RLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV+FNATLFA+VR L IKTDG+ +D+ N ELR IK+IWKRT+ ++LDQVV +D+VTVGKFYAT+LIQ++FRR+K+++ EQ+G ++L RT + S L IS L DE + P H RR HS+FG +M+ L R + R + H +L R++
Sbjct: 8 TETDNVQNKQKATTPKRTQRRGGKQQLDRPERALFCLTLKNPLRIFCIKIVDSKLFEYFILLTIFANCVALAVYTPYPSGDSNITNQMLEKIEYIFLVIFTSECVMKIIAYGFVLHTGSYLRNGWNFLDFFIVVIGMISTALSNLVKEGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMIPLLHIALLVLFVIIIYAIIGLELFSGKLHKTCRHSN---------TGEYLN---DLDELHACGVGFKCPSGYECFDDWVGPNDGITNFDNFGLSMLTVFQCITLEGWTDVLYSIQDAMGSSWEWIYFVSMVILGAFFVMNLILGVLSGEFSKERTKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDPDAQIIEDCHKNKVK--------------------EVVSIDNLKDHENETQQTDSWFRSQKKYLERINRRIRRACRKAVKSQAFYWLIILLVFLNTGVLATEHYRQPIWLDQFQEYTNIFFIALFTCEMILKMYSLGFQGYFVSLFNRFDCFVVIGSISEMVLTSSELMAPLGVSVLRCVRLLRVFKVTKYWHSLSNLVASLLNSIQSIASLLLLLFLFIVIFGLLGMQVFGGRFTFKPEEEKPRSNFDSFYQSLLTVFQILTGEDWNVVMYDGIRAYGGVFSFGIVACIYYIILFICGNYILLNVFLAIAVDNLADADSL---------------STIEKEDESQIQLDNQIKNEMENEEYLQNGDHISFKAEFGADLDTYLQDEECGSYSDDENTYNKLGGVKQRV---------SSLPRRNTNTDMDRIKKDIPYGTSFFIFSHTNRFRIFCHRLCNHSNFGNFILCCIMFSSAMLAAENPLKADASRNIVLNKFDYFFTAVFTIELVLKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISIFFNSNAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFSCSDGSKVYESDCHGTYLFYENGDINKPRLKEREWKNNKFHFDDVAKAMLTLFTVSTFEGWPTLLYVSIDSNKENGGPIYNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCELDKNQRNCIEFALKAKPVRRYIPKHSIQYKVWWFVTSSSFEYSIFVLIMINTVTLAMKFYKQPEYYSEILDALNMIFTAVFSLEFIFKLAAFRFKNYFGDAWNTFDFIIVLGSFIDIVYSEIKTKEQALATCDGQSCNKAKGGSTLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIMLE---EGTSIDRNNNFQTFPQAVLVLFRSATGEAWQEIMMACSPRDDVKCDPESDA-----------------------------------------------VNNCGSSIAFPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRLPLAIKTDGN-IDEANAELRATIKQIWKRTNPRLLDQVVLTGNDDEVTVGKFYATYLIQDYFRRFKKRK--EQEGKCDQTENAVTLQAGLRTLQQNSPALKRTISGYL------DELASEADPMH----RRHHSLFGKVMSSLLRHEEITSSKIKHLSRTKTIPYQVEFLQHKVQLERNK 1625
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|Q24270|CAC1D_DROME (Voltage-dependent calcium channel type D subunit alpha-1 OS=Drosophila melanogaster OX=7227 GN=Ca-alpha1D PE=1 SV=2) HSP 1 Score: 1732.61 bits (4486), Expect = 0.000e+0 Identity = 999/1701 (58.73%), Postives = 1200/1701 (70.55%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPV-PCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFD-KKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIY--------------DHVNGTNNNHR--GDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHC--LPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDD-VTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGST--RRDSNASPS 6000
R R + RPQRALFCL+++NP R CI+IVEWKPFE+LIL TIFANC ALA TPYP DSN N LEK+E VF+VIFT ECV+KILA+GF++H GAYLRNGWNLLDF IV+IG IST LS++ + DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPLFHIALL LFVIIIYAIIGLELFSGKLH C + E + PC GYQC Y C W GPN GIT+FDNFGLAMLTVFQC+T+EGWT ++Y I D++G W W+YF+S++I+G+FFVMNL+LGVLSGEFSKER KAK RG +QK RE+ Q +ED++GYLDWI AEDI D +GK + ++ E G Q +K R R R + + ++ +++ LVFLNTGVL +EHY Q WLD+FQ N+ F+ LFT EML+KMYSLG + YF +FNRFD FVVI SI E ++ T MPPLGVSVLRC RLLRVFKVT+YW SL NLV SLL S++SI SLL+LLFLFIVIF+LLGMQ+FGGKFNFD K+ K R NFD F Q+LLTVFQI+TGEDWN VMY GI +YG + L+C+Y++ILFICGNYILLNVFLAIAVDNLAD S ++ EK+E + +E+ S + +P ID + ++ +E++ DE KM +++E E E +E DEE T+ RR+SEV KI PIP +SFF+F N+FR FCH++CNH +FGNI+L CIM SSAMLAAE+PL A N++LN FDY FT+VFT+E+ LK+I+YG V H+GAFCRS+ N+LDLLVV S+IS +++AISVVKILRVLRVLRPLRAINRAKGLK VVQCV+VAVK+IGNI+LVT LL+FMFAVIGVQLF GKF C D SK T C G Y+ Y++ D+ K + +REW NN +FD+V MLTLF VSTFEGWPG+LY SIDS KE+ I+N RPIV+ +YI YII+IAFFM+NIFVGFVIVTFQ EGE+EYKNC+LDKNQR CIEFALKAKPVRRYIPK +Y+VWW +TS FEY IF+LIM+NT++LA+KF QP Y +++D LNM+FT VF +EF+ KLAAF FKNYF DAWNVFDFIIVLGSFIDI+Y D V G + + G LISINFFRLFRVMRLVKLLS+GEGIRTLLWTF+KSFQALPYVALLIV+LFFIYAV+GMQ+FGKI + I NNNFQTF QA+LVLFRSATGEAWQ IM+ C PD CD SD + CGS+ AYPYFISFY++CSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF+RLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV+FNATLFA+VRT+L IKTDG+ +D N ELR IK+IWKRT+ K+LDQVVPP GNDD VTVGKFYAT+LIQ++FRR+K KR E++ + S ++L RT S L IS L DE D++ P H RR H++FG++ + ++R G+ RR + A+ S
Sbjct: 579 RQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRDEITGEYEENIRPCGV----GYQCPP------GYKCYGG------WDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDAVGGLISDGKGKQ-------------------PNEMDSTENLGEEMPEVQMTESRWRKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIV-LVFLNTGVLATEHYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYGALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPH----------DESAQKKSHSPTPTIDGMDDHLSIDIDMEQQELD----DED--KMDHETLSDEEVREMCEEEEEVDEEGMITARPRRMSEVNTATKILPIPPGTSFFLFSQTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLNKVLNKFDYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGG---NAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDTPGE----------------------------------------------PCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGN-IDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFK-KRKEQEGKEGHPDSNTVTLQAGLRTLHEVSPALKRAISGNL------DELDQEPEPMH----RRHHTLFGSVWSSIRRHGNGTFRRSAKATAS 2166
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|Q02485|CAC1S_RAT (Voltage-dependent L-type calcium channel subunit alpha-1S OS=Rattus norvegicus OX=10116 GN=Cacna1s PE=1 SV=2) HSP 1 Score: 1642.09 bits (4251), Expect = 0.000e+0 Identity = 929/1716 (54.14%), Postives = 1167/1716 (68.01%), Query Frame = 1
Query: 958 GGRKRTPARSQSGN-PRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----------SEG-GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMM----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNET-SRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGK----ENGK--ESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNG--DIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRR---VSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNG---------------TNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGS 5970
G RK+ P + PRP RALFCLTL+NP RK CI +VEWKPFE +IL TIFANC ALA P PE D+NT+N LEK+E F+++F+ E +KI+A+GF+ H AYLR+GWN+LDF+IV +G+ + +L ++ S+G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI +AM+PLFHIALL LF++IIYAIIGLELF GK+H TCY D++ E P PC+ +G C N +E W GPN GIT FDNFG +MLTV+QCI+MEGWT ++YW+ND++G WPWIYFV+LI++GSFF++NLVLGVLSGEF+KEREKAK RG +QK RE+ Q +ED++GY+ WI E + D+ +GK E G ES +++ GL K + H +Q VF + LVKS+ FYW+VI++V LNT + SEH+ Q +WL Q+ AN + + LFT+EML+KMY LG+R YF +FNRFD FVV ILEI+++++ AM PLG+SVLRC RLLR+FK+T+YW+SL NLV SLL S++SI SLL+LLFLF++IF+LLGMQLFGG+++F+ RSNFD+F Q+L++VFQ+LTGEDWN VMY+GI +YG +L C+Y++ILF+CGNYILLNVFLAIAVDNLA+ S EE K S P+ E+ R T ++L + + G A + + + ++ K+ +++E+ + A R ++E+ KEK PIP ASSFFIF P NK R CH I N F N +L+ I++SSA LAAEDP+ A+S RN+IL YFDY+FT+VFTVEI LK+ TYG H G+FCR+ NILDLLVV S+IS + + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI+LVT LL+FMFA IGVQLF GKF SCND+SK T CRG Y Y + D ++ + R+WI+N +FDNV +AM++LF VSTFEGWP +LYK+IDS +ED +YNNR ++IF+I YII+IAFFM+NIFVGFVIVTFQ++GE EYKNCELDKNQR+C+++ALKA+P+R YIPK ++Y+VW+++TS FEY++F LIMLNTI L ++ Q ++ + D LN+ FT +FT+E +LKL AF + YF D WNVFDF+IV+GS ID+I ++ N + IS FFRLFRVMRL+KLLSR EG+RTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ I+L C CD SD E Y CG+NFAY YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF +W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK+CPHR AC LV MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IKKIWKRTS K+LDQV+PP G+D+VTVGKFYATFLIQE FR++ KR EE G + RT + P I +T E E+ G RRT +FG + N L+R S
Sbjct: 10 GLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISVVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTAILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCA-------------RTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFI-------------------RHWRQWNRVFRWKCHD----------------LVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFMIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSA------------QKAKAEERKRRKMSRGLPDKSEEERSTMTKKLEQKPKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPASPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDTLLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKRCDPESDYAPGEEY-------------------------------------------ACGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNS 1617
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|Q02789|CAC1S_MOUSE (Voltage-dependent L-type calcium channel subunit alpha-1S OS=Mus musculus OX=10090 GN=Cacna1s PE=1 SV=2) HSP 1 Score: 1637.47 bits (4239), Expect = 0.000e+0 Identity = 929/1716 (54.14%), Postives = 1167/1716 (68.01%), Query Frame = 1
Query: 958 GGRKRTPARSQSGN-PRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----------SEG-GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMM----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNET-SRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGK----ENGK--ESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNG--DIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQ---TSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNG---------------TNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGS 5970
G RK+ P + PRP RALFCLTL+NP RK CI IVEWKPFE +IL TIFANC ALA P PE D+NT+N LEK+E F+++F+ E +KI+A+GF+ H AYLR+GWN+LDF+IV +G+ + +L ++ S+G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI +AM+PLFHIALL LF++IIYAIIGLELF GK+H TCY D++ E P PC+ +G C N +E W GPN GIT FDNFG +MLTV+QCI+MEGWT ++YW+ND++G WPWIYFV+LI++GSFF++NLVLGVLSGEF+KEREKAK RG +QK RE+ Q +ED++GY+ WI E + D+ +GK E G ES +++ GL K + H +Q VF + LVKS+ FYW+VI++V LNT + SEH+ Q +WL Q+ AN + + LFT+EML+KMY LG+R YF +FNRFD FVV ILEI+++++ AM PLG+SVLRC RLLR+FK+T+YW+SL NLV SLL S++SI SLL+LLFLFI+IF+LLGMQLFGG+++F+ RSNFD+F Q+L++VFQ+LTGEDWN VMY+GI +YG +L C+Y++ILF+CGNYILLNVFLAIAVDNLA+ S EE K S P+ E+ R T ++L + + G A + + + ++ K+ +++E+ + + R ++E+ KEK PIP ASSFFIF P NK R CH I N F N +L+ I++SSA LAAEDP+ A+S RN+IL YFDY+FT+VFTVEI LK+ TYG H G+FCR+ NILDLLVV S+IS + + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI+LVT LL+FMFA IGVQLF GKF SCND+SK T CRG Y Y + D ++ + R+WI+N +FDNV +AM++LF VSTFEGWP +LYK+IDS +ED +YNNR ++IF+I YII+IAFFM+NIFVGFVIVTFQ++GE EYKNCELDKNQR+C+++ALKA+P+R YIPK ++Y+VW+++TS FEY++F LIMLNTI L ++ Q ++ + D LN+ FT +FT+E +LKL AF + YF D WNVFDF+IV+GS ID+I ++ N + IS FFRLFRVMRLVKLL+R EG+RTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ I+L C +CD SD E + CG+NFAY YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF +W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK+CPHR AC LV MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IKKIWKRTS K+LDQV+PP G+D+VTVGKFYATFLIQE FR++ KR EE G + RT + P I T E E+ G RRT +FG + N L+R S
Sbjct: 10 GLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTVILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCA-------------RTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFI-------------------RHWRQWNRVFRWKCHD----------------LVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSA------------QKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMVLKLIAFKPRAYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHT-------------------------------------------CGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEIHRAISGDPTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNS 1617
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. UniProt/SwissProt
Match: sp|P07293|CAC1S_RABIT (Voltage-dependent L-type calcium channel subunit alpha-1S OS=Oryctolagus cuniculus OX=9986 GN=CACNA1S PE=1 SV=1) HSP 1 Score: 1627.45 bits (4213), Expect = 0.000e+0 Identity = 924/1716 (53.85%), Postives = 1161/1716 (67.66%), Query Frame = 1
Query: 958 GGRKRTPARSQSGN-PRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----------SEG-GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYS-KNDVMM----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNET-SRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGK----ENGK--ESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNG--DIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQ---TSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNG---------------TNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGS 5970
G RK+ P + PRP RALFCLTL+NP RK CI IVEWKPFE +IL TIFANC ALA P PE D+N++N LEK+E F+ +F+ E +KI+A+GF+ H AYLR+GWN+LDF+IV +G+ + +L ++ S+G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI +AM+PLFHIALL LF++IIYAIIGLELF GK+H TCY D++ E P PC+ +G C N +E W GPN GIT FDNFG +MLTV+QCITMEGWT ++YW+ND++G WPWIYFV+LI++GSFF++NLVLGVLSGEF+KEREKAK RG +QK RE+ Q +ED++GY+ WI E + ++ +GK E G ES +++ GL K + H +Q VF + LVKS+ FYW+VI++V LNT + SEH+ Q +WL Q+ AN + + LFT+EML+KMY LG+R YF +FNRFD FVV ILE++++++ AM PLG+SVLRC RLLR+FK+T+YW+SL NLV SLL S++SI SLL+LLFLFI+IF+LLGMQLFGG+++F+ RSNFD+F Q+L++VFQ+LTGEDWN VMY+GI +YG +L C+Y++ILF+CGNYILLNVFLAIAVDNLA+ S EE K S P+ E+ + A++L + + G A + + + ++ K+ +++E+ + + R ++E+ KEK PIP ASSFFIF P NK R CH I N F N +L+ I++SSA LAAEDP+ AES RN+IL YFD FTSVFTVEI LK+ TYG H G+FCR+ NILDLLVV S+IS + + ISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI+LVT LL+FMFA IGVQLF GKF SCND+SK T CRG Y Y + D ++ + R+WI+N +FDNV +AM++LF VSTFEGWP +LY++IDS +ED +YNNR ++IF+I YII+IAFFM+NIFVGFVIVTFQ++GE EYKNCELDKNQR+C+++ALKA+P+R YIPK ++Y+VW+++TS FEY++F LIMLNTI L ++ Q + + D LN+ FT +FT+E +LKL AF + YF D WNVFDF+IV+GS ID+I ++ N + IS FFRLFRVMRL+KLLSR EG+RTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ I+L C +CD SD E Y CG+NFAY YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF +W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK+CPHR AC LV MNMPLNSDGTV FNATLFALVRT LKIKT+G+ +Q NEELR +IKKIWKRTS K+LDQV+PP G+D+VTVGKFYATFLIQE FR++ KR EE G + RT + P I +T E E+ RRT +FG + L+R S
Sbjct: 10 GLRKKQPKKPLPEVLPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLTVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTAILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYYIGTDIVATVENEKPSPCA-------------RTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVEDLREGKLSLEEGGSDTESLYEIEGLNKIIQFI-------------------RHWRQWNRVFRWKCHD----------------LVKSRVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDIANRVLLSLFTIEMLLKMYGLGLRQYFMSIFNRFDCFVVCSGILELLLVESGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSA------------QKAKAEERKRRKMSRGLPDKTEEEKSVMAKKLEQKPKGEGIPTTAKLKVDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKVRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSTISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDLSKMTEEECRGYYYVYKDGDPTQMELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYRAIDSNEEDMGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYHQSEEMNHISDILNVAFTIIFTLEMILKLLAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEYT-------------------------------------------CGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGN-FEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEERIFRRTGGLFGQVDTFLERTNS 1617
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. TrEMBL
Match: G0YP32 (Voltage-dependent L-type calcium channel subunit alpha OS=Dugesia japonica OX=6161 PE=2 SV=1) HSP 1 Score: 4135.49 bits (10724), Expect = 0.000e+0 Identity = 2321/2654 (87.45%), Postives = 2460/2654 (92.69%), Query Frame = 1
Query: 223 MLNDRIYPNNMTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPGQFXXXXXXXXXXXXXXXXXXGVHEYSDGDGDYGDQNQRRPLVSQPAKINIDEIPQLQISSDQNEPNEPKYDLNNNNVFKMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTNPPAIYSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRPLNLAALTLSAQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETS-RWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNN-HRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGR-GSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFXXXXXXXXXXXXXXXXXKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYXXXXXXXXXXXXFYPQNIPSNRCSNVXXXXXXXXXXXXXXNXXXXXXXXXXXXAFIYPLSRGDXXXXXXXXXXXHQRYQXXXXXXXXMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSXXXXXXXXXXLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTY-QKNYKYPQLLTEETFSRRARMDANSXXXXXXXXXXXXSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGT 8172
MLNDRIYPNN+TGGRSGID+CHP QYSAPMHQYRQL+ D+P+YD+H RNTEYKCVENDY+E+ YR++ R NYQLNYSPPGQFD+EEE+E+D + + E VHEYSDGDGDYG++NQ+RPLVSQPAKINIDEIPQLQIS +QNEP++ K+D+NNN+V K+DDD+S SS N++ A A TNPPAIYSGFGGLGSGLGGGGLGGILGVAAAAAQQQGRPLNLAALTLSAQIASGGRKR PARSQSGNPRP+RALFCLTLRNPFRKFCI IVEWKPFEYLIL TIFANC ALAANTPYPERDSN +NSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY K +++ME+PVPCSTS++KGYQCDDFH SG KY CKD KN +S RW GPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKER KAKKRGKYQKAREQMQF+EDVQGYLDWIGAAEDISDDE+N+GKENGKESRFKLCGLCKSS KSDDGDDQLSDK+DLETEGG HHSQQQQYVFCFPLKSRRGRKWNRRCRRI RRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQS+WLDSFQ+TANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSI EIVMIQT MPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIF+LLGMQLFGGKFNF+KK KPRSNFDSF QSLLTVFQILTGEDWNEVMYDGIRSY NLG+S+MLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEE E N + EE K C S++VSPN+DEK RFTDAERLIKSEEMNGDI ++SMRKMSTR D E +N+EEY EG EEDEENGQ SAIRRVSEVMAKEKIKPIPNASSFFIFGPNN+FRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAES RN+ILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCND+SK+T C+G +I YNEADIAK VNKREW NNPLNFDNVPNAMLTLFAVSTFEGWPG+LYKSIDSFKEDYSG YNNRP+VSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFD QP +YE+VMDYLNMVFTGVFTVEF+LKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVN T+N+ HRGD+LISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKE +EINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDA+CDA SDQIRKEY N+T+ + + +SM+ WPP N K KINKYIS +QD+AKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGM YSQ+KRLSLMPFRTHGR GSGPL SLISPTLVTTNECDEKDKDYLP+HLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSIN S E RDRSNSRPMIL+QSKSPTNHPPVKLTLAPVIEGQVISN+EYS EIPPK+PKTVSKQSLNYDKK T+KQ + EY +R+K+S R PLDIDLPL RSNVFPRPSRSQSSESPESIQRKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSH RI V PSNIDSR+Y+NK R + + + YYKGSPN+YS QSS ESSE+Q+YP+NIPSNRCSNVQIIDLDISLSSS DN +E+EY G E+EAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSS+GQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFP+ KE+VPFNPYEKSIANQLRNIR+SKIVN+PK KYHQE+IDNS++ N SDNES S + G F+LEEWR+SPPPTPAPN N+RY QR ++E R E QK N +RYDS RQ ERSSY++ HQCSLEEE I+ST+DY+EEIDQ K NQYE+DYNRYM+KYA SNPRS ++ PRNC DPR+SRNPMPDLISSTDWLL+KCQN P + N + QKNYKYPQ LTEETFSRRARMDANSPPPEPAPRQELP+QYVLSQQRESDE++Y+QMS+ENIDKSF LRT SKQYSDMGSQT+LEM+EPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMS +++RG HP T
Sbjct: 1 MLNDRIYPNNLTGGRSGIDHCHPTQYSAPMHQYRQLY-ADRPYYDTHNRNTEYKCVENDYLETGYRYDTRNNYQLNYSPPGQFDEEEEDEDDRNYFDNEER-VHEYSDGDGDYGNKNQKRPLVSQPAKINIDEIPQLQISCEQNEPHDVKFDMNNNSVIKVDDDQSVSSNNIIKSQNDKTPCAKTVA-----TNPPAIYSGFGGLGSGLGGGGLGGILGVAAAAAQQQGRPLNLAALTLSAQIASGGRKRAPARSQSGNPRPKRALFCLTLRNPFRKFCIGIVEWKPFEYLILLTIFANCFALAANTPYPERDSNMVNSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYYKQELVMENPVPCSTSISKGYQCDDFHLSGLKYSCKDFKNVSSIRWEGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKERLKAKKRGKYQKAREQMQFEEDVQGYLDWIGAAEDISDDEDNEGKENGKESRFKLCGLCKSSGKSDDGDDQLSDKMDLETEGGGHHSQQQQYVFCFPLKSRRGRKWNRRCRRIFRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSLWLDSFQDTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSIGEIVMIQTKLMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFALLGMQLFGGKFNFEKKGKPRSNFDSFWQSLLTVFQILTGEDWNEVMYDGIRSYSNLGRSAMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEEEGNNAENEEKKVCTSNSVSPNLDEKNRFTDAERLIKSEEMNGDIGEDSMRKMSTRGDKEIDNEEEYGEGGEEDEENGQASAIRRVSEVMAKEKIKPIPNASSFFIFGPNNRFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESPRNKILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDLSKSTFNVCKGHFILYNEADIAKAVVNKREWTNNPLNFDNVPNAMLTLFAVSTFEGWPGLLYKSIDSFKEDYSGTYNNRPVVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDNQPLQYEKVMDYLNMVFTGVFTVEFVLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNVTSNSPHRGDKLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEFREINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAVCDAYSDQIRKEYINVTLTKGKLDSRNNLTESMITWPP-NVSKYKINKYISQHQDIAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMTYSQNKRLSLMPFRTHGRAGSGPLHSLISPTLVTTNECDEKDKDYLPAHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINQSNESHRDRSNSRPMILSQSKSPTNHPPVKLTLAPVIEGQVISNDEYSTEIPPKIPKTVSKQSLNYDKKIPTNKQSKTEYPIREKVSHRPNPLDIDLPLHRSNVFPRPSRSQSSESPESIQRKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHYRISAVHPSNIDSRKYTNKGRPSMSHNNEYYKGSPNDYSGQSSGESSELQYYPKNIPSNRCSNVQIIDLDISLSSSPDNEEEYEYGGAEDEAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSSLGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPSAKENVPFNPYEKSIANQLRNIRQSKIVNLPKRKYHQEMIDNSRYVNASDNESNSPENIPQGAFDLEEWRDSPPPTPAPNNNIRYSRQRIDQEPLRAEPQK-NMHRYDSPRQSERSSYMMRHQCSLEEEPIESTDDYEEEIDQSKAPNQYEQDYNRYMMKYASSNPRSHYMVPRNCYIDPRMSRNPMPDLISSTDWLLDKCQNIPVLANRMFQQKNYKYPQQLTEETFSRRARMDANSPPPEPAPRQELPTQYVLSQQRESDEIDYMQMSEENIDKSFKTLRTHSKQYSDMGSQTNLEMTEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSPVVNRGPIKSMRHPTKT 2645
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. TrEMBL
Match: A0A068WA30 (Voltage-dependent L-type calcium channel subunit alpha OS=Echinococcus granulosus OX=6210 GN=EgrG_000960800 PE=3 SV=1) HSP 1 Score: 2033.84 bits (5268), Expect = 0.000e+0 Identity = 1139/1723 (66.11%), Postives = 1297/1723 (75.28%), Query Frame = 1
Query: 910 RPLNLAALTLSAQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-SEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYS-KNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETS-----------------------------RWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPD-AMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAG-NDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRR 5979
+PLNL L L+AQ + RKR +R+Q+ RPQRALFCL+LRNP RK CI IVEWKPFEYLIL TI NC AL ++TPYP+ DSN NS LEK+E VFIVIFT EC+LKI+A GF+MHPGAYLRNGWN+LDF IV +GL+ +L +M G DVKALRAFRVLRPLRLVSGLPSLQVV+N+I+RAMVPL HIALL +FVI +YAI+GLELFSGKLH+TCY +M++P PCS +G+ C F ++C D + + RW GPN GIT+FDN +MLTVFQC+TMEGWT ++YW+NDS GM WP++YFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQF EDVQGYLDWIGAAED+SDDE+N + + KE RF CGLC+ S+ +D D+ SD+ D SQQ+QY FCFP++ RR R+ NRRCRR CRR+VKSQ FYW VIVLVFLNTGVLTSEHY Q WLD FQN AN++FVVLFT+EML+KMYSLG+RCYFD+MFNRFD FVVI SILEIV I T MPPLGVSV RCARLLRVFKVTRYW+SLRNLVGSLLASM+SI SLLVLLFLFIVIF+LLGMQ+FGG+FNF KPRSNFD+F Q+L TVFQILTGEDWNE MY GI+SY S++ CLYYV+LFICGNYILLNVFLAIAVDNLADTG ++K E T+ DG++ A S + D F AE KS + +E+ +S + ++E S S + KIKPIP ASSFFIFGP N FR FCH+ICNHP+F N+VLVCI+VSSAMLAAEDPL A S RN ILNYFDY FTSVFTVEITLKVITYG FH GAFCRS+NN+LDL+VVLTSIISYPI D ISVVKILRV RVLRPLRAINRAKGLK VVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLF GKF CND ++ C G +I Y+ D + + +R WIN PLNFDNVPN +LTLF STFEGWP +LY+SIDS+ ED+ +YN RP+V IFY+A+I+V+AFFM+NIFVGFVIVTFQQEGE+EYK CELDKNQRKCIEFALKA+PVRRYIPK+ F+YR+WW +TS+PFEY IF+ I++NTI L +KF+ QP Y +DYLNM+FTGVFTVEF+LKL A FKNYF+D WNVFDFIIV+GSF+DI+ H+ + ISINFFRLFRVMRL+KLLSRGEGIRTLLWTFVKSFQALPYVALLI+MLFFIYAVIGMQMFGKI N I N NFQTFPQA+L+LFRSATGEAWQ+IM C + A CD SD+ R +G D V CGS FAYP+FISFY+ICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKI+PPLGFGK CPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKT+GST DQLNEELR VIKKIWK TS K+LDQVVPPAG NDDVTVGKFYATFLIQEWFRRWK K+ EE K + Y Q KR S+MPFR GR SL+ P +EK S ++R S+ G+MM+ LQRVGS RR
Sbjct: 106 KPLNLTNLALAAQ--TNARKRPASRAQAAGSRPQRALFCLSLRNPLRKMCIGIVEWKPFEYLILITILGNCFALGSHTPYPDGDSNGTNSILEKVENVFIVIFTIECLLKIVALGFVMHPGAYLRNGWNILDFTIVCLGLLQPLLQRMLDRSGVDVKALRAFRVLRPLRLVSGLPSLQVVLNAIIRAMVPLLHIALLVIFVITMYAIVGLELFSGKLHATCYDIYTGEIMDNPTPCSLG-RQGHICK------FPFVCHDFRPNMTKAAIAERRVIVANMSADPYAFTGFIKLPERWPGPNYGITNFDNLAASMLTVFQCVTMEGWTNVLYWMNDSQGMEWPFLYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFAEDVQGYLDWIGAAEDLSDDEDNVNRLDVKEKRFNFCGLCRRSQGGEDEDEDDSDRDDCGYR--TQSSQQKQYFFCFPIRGRRSRRLNRRCRRSCRRMVKSQTFYWTVIVLVFLNTGVLTSEHYGQPKWLDIFQNDANVVFVVLFTIEMLLKMYSLGVRCYFDYMFNRFDCFVVICSILEIVFIMTKLMPPLGVSVFRCARLLRVFKVTRYWNSLRNLVGSLLASMRSIASLLVLLFLFIVIFALLGMQIFGGRFNFLSLRKPRSNFDNFYQALTTVFQILTGEDWNEAMYMGIKSYSTQPFGSLV-CLYYVVLFICGNYILLNVFLAIAVDNLADTGQSKGKQKSEA-------TSEDGDDNTAGMDIVKSADGDS---FNSAEEDGKSTFLTNSKNNENEEYVSIE--------------ERDNESESVYSDEHHGSAENLQPKIKPIPEASSFFIFGPRNPFRVFCHYICNHPYFNNVVLVCILVSSAMLAAEDPLKANSYRNIILNYFDYFFTSVFTVEITLKVITYGFAFHKGAFCRSANNLLDLMVVLTSIISYPIALDTISVVKILRVSRVLRPLRAINRAKGLKHVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFAGKFHYCNDEARFYKEECAGPFIKYDSEDPSLPELVERRWINYPLNFDNVPNGLLTLFVASTFEGWPALLYQSIDSYAEDHGKVYNCRPVVVIFYVAFIVVVAFFMVNIFVGFVIVTFQQEGEQEYKGCELDKNQRKCIEFALKARPVRRYIPKERFQYRIWWFVTSQPFEYCIFIFILINTICLGMKFEGQPPVYADALDYLNMIFTGVFTVEFILKLTALSFKNYFNDLWNVFDFIIVVGSFVDIVLSHIA------ENSKFISINFFRLFRVMRLIKLLSRGEGIRTLLWTFVKSFQALPYVALLILMLFFIYAVIGMQMFGKIALNNPD--SAITVNANFQTFPQAVLILFRSATGEAWQDIMFSCAGETAYCDKQSDESRTA--------------VGATDRTV------------------------CGSAFAYPFFISFYIICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKISPPLGFGKLCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTEGSTPDQLNEELRAVIKKIWKHTSPKLLDQVVPPAGSNDDVTVGKFYATFLIQEWFRRWKLKKAEEHKHLPYGQHKRHSIMPFR--GR------SLMHPE-------EEKGGG---SSASDDKRQMSLLGSMMHALQRVGSYRR 1728
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. TrEMBL
Match: W6UN84 (Voltage-dependent L-type calcium channel subunit alpha OS=Echinococcus granulosus OX=6210 GN=EGR_02129 PE=3 SV=1) HSP 1 Score: 1963.73 bits (5086), Expect = 0.000e+0 Identity = 1126/1804 (62.42%), Postives = 1294/1804 (71.73%), Query Frame = 1
Query: 910 RPLNLAALTLSAQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-SEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY------------------SKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETS-----------------------------RWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALK----------------------------------FDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFK-----------NYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPP-HNFVKVKINK---------YISHYQDVAK----------CGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAG-NDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRR 5979
+PLNL L L+AQ + RKR +R+Q+ RPQRALFCL+LRNP RK CI IVEWKPFEYLIL TI NC AL ++TPYP+ DSN NS LEK+E VFIVIFT EC+LKI+A GF+MHPGAYLRNGWN+LDF IV +GL+ +L +M G DVKALRAFRVLRPLRLVSGLPSLQVV+N+I+RAMVPL HIALL +FVI +YAI+GLELFSGKLH+TCY S +M++P PCS +G+ C F ++C D + + RW GPN GIT+FDN +MLTVFQC+TMEGWT ++YW+NDS GM WP++YFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQF EDVQGYLDWIGAAED+SDDE+N + + KE RF CGLC+ S+ +D D+ SD+ D SQQ+QY FCFP++ RR R+ NRRCRR CRR+VKSQ FYW VIVLVFLNTGVLTSEHY Q WLD FQN AN++FVVLFT+EML+KMYSLG+RCYFD+MFNRFD FVVI SILEIV I T MPPLGVSV RCARLLRVFKVTRYW+SLRNLVGSLLASM+SI SLLVLLFLFIVIF+LLGMQ+FGG+FNF KPRSNFD+F Q+L TVFQILTGEDWNE MY GI+SY S++ CLYYV+LFIC ILLNVFLAIAVDNLADTG G++ S S + D+ T D ++KS + + + E K + EN+E + + ++E S S + KIKPIP ASSFFIFGP N FR FCH+ICNHP+F N+VLVCI+VSSAMLAAEDPL A S RN ILNYFDY FTSVFTVEITLKVITYG FH GAFCRS+NN+LDL+VVLTSIISYPI D ISVVKILRV RVLRPLRAINRAKGLK VVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLF GKF CND ++ C G +I Y+ D + + +R WIN PLNFDNVPN +LTLF STFEGWP +LY+SIDS+ ED+ +YN RP+V IFY+A+I+V+AFFM+NIFVGFVIVTFQQEGE+EYK CELDKNQRKCIEFALKA+PVRRYIPK+ F+YR+WW +TS+PFEY IF+ I++NTI L +K F+ QP Y +DYLNM+FTGVFTVEF+LKL A FK NYF+D WNVFDFIIV+GSF+DI+ H+ + ISINFFRLFRVMRL+KLLSRGEGIRTLLWTFVKSFQALPYVALLI+MLFFIYAVIGMQMFGKI N I N NFQTFPQA+L+LFRSATGEAWQ+IM C CD L + S+ ++PP ++ ++ ++ Y D ++ CGS FAYP+FISFY+ICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKI+PPLGFGK CPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKT+GST DQLNEELR VIKKIWK TS K+LDQVVPPAG NDDVTVGKFYATFLIQEWFRRWK K+ EE K + Y Q + L + P G GS + D+K R S+ G+MM+ LQRVGS RR
Sbjct: 163 KPLNLTNLALAAQ--TNARKRPASRAQAAGSRPQRALFCLSLRNPLRKMCIGIVEWKPFEYLILITILGNCFALGSHTPYPDGDSNGTNSILEKVENVFIVIFTIECLLKIVALGFVMHPGAYLRNGWNILDFTIVCLGLLQPLLQRMLDRSGVDVKALRAFRVLRPLRLVSGLPSLQVVLNAIIRAMVPLLHIALLVIFVITMYAIVGLELFSGKLHATCYDIYTGESFVCNFRYLPIFSFFGEIMDNPTPCSLG-RQGHICK------FPFVCHDFRPNMTKAAIAERRVIVANMSADPYAFTGFIKLPERWPGPNYGITNFDNLAASMLTVFQCVTMEGWTNVLYWMNDSQGMEWPFLYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFAEDVQGYLDWIGAAEDLSDDEDNVNRLDVKEKRFNFCGLCRRSQGGEDEDEDDSDRDDCGYR--TQSSQQKQYFFCFPIRGRRSRRLNRRCRRSCRRMVKSQTFYWTVIVLVFLNTGVLTSEHYGQPKWLDIFQNDANVVFVVLFTIEMLLKMYSLGVRCYFDYMFNRFDCFVVICSILEIVFIMTKLMPPLGVSVFRCARLLRVFKVTRYWNSLRNLVGSLLASMRSIASLLVLLFLFIVIFALLGMQIFGGRFNFLSLRKPRSNFDNFYQALTTVFQILTGEDWNEAMYMGIKSYSTQPFGSLV-CLYYVVLFICD--ILLNVFLAIAVDNLADTGQS------------------KGKQ----KSEATSEDGDDNTAGMD---IVKSADGDSFNSAEEDGKSKVLLLENNENEEYVSIEERDNESESVYSDEHHGSAENLQPKIKPIPEASSFFIFGPRNPFRVFCHYICNHPYFNNVVLVCILVSSAMLAAEDPLKANSYRNIILNYFDYFFTSVFTVEITLKVITYGFAFHKGAFCRSANNLLDLMVVLTSIISYPIALDTISVVKILRVSRVLRPLRAINRAKGLKHVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFAGKFHYCNDEARFYKEECAGPFIKYDSEDPSLPELVERRWINYPLNFDNVPNGLLTLFVASTFEGWPALLYQSIDSYAEDHGKVYNCRPVVVIFYVAFIVVVAFFMVNIFVGFVIVTFQQEGEQEYKGCELDKNQRKCIEFALKARPVRRYIPKERFQYRIWWFVTSQPFEYCIFIFILINTICLGMKNTAFLHKVKSIVVINALCVRVLVTILQDLCSHFQFEGQPPVYADALDYLNMIFTGVFTVEFILKLTALSFKASPHSYLIRFGNYFNDLWNVFDFIIVVGSFVDIVLSHIA------ENSKFISINFFRLFRVMRLIKLLSRGEGIRTLLWTFVKSFQALPYVALLILMLFFIYAVIGMQMFGKIALNNPDS--AITVNANFQTFPQAVLILFRSATGEAWQDIMFSC-AGVSCDLL-----------------HVIAPCYPHSLALFPPFSHYRQIDVSSRGWCATETAYCDKQSDESRTAVGATDRTVCGSAFAYPFFISFYIICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKISPPLGFGKLCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTEGSTPDQLNEELRAVIKKIWKHTSPKLLDQVVPPAGSNDDVTVGKFYATFLIQEWFRRWKLKKAEEHKHLPYGQGRSL-MHPEEEKGGGS--------------SASDDK-------------RQMSLLGSMMHALQRVGSYRR 1873
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. TrEMBL
Match: A0A068YHX8 (Voltage-dependent L-type calcium channel subunit alpha OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000961000 PE=3 SV=2) HSP 1 Score: 1948.71 bits (5047), Expect = 0.000e+0 Identity = 1096/1757 (62.38%), Postives = 1267/1757 (72.11%), Query Frame = 1
Query: 910 RPLNLAALTLSAQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-SEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYS-KNDVMMESPVPCSTSVNKG-----YQCDDFHSSGFKYMCKDNKNETS-----------------RWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAI---RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPD-AMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAG-NDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHS--TELPRDRSNSRPMILNQSKSPT 6087
+PLNL +L L+AQ + RKR +R+Q+ RPQRALFCL+LRNP RK CI IVEWKPFEYLIL TI NC AL ++TPYP+ DSN NS LEK+E VFIVIFT EC+LKI+A GF+MHPGAYLRNGWN+LDF IV +GL+ +L +M G DVKALRAFRVLRPLRLVSGLPSLQVV+N+I+RAMVPL HIALL +FVI +YAI+GLELFSGKLH+TCY +M++P PCS S + C DF + K + ++ + RW GPN GIT+FDN +MLTVFQC+TMEGWT ++YW+NDS GM WP++YFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQF EDVQGYLDWIGAAED+SDDE+N + + KE RF LCGLC+ S+ ++ D+ SD+ D SQQ+QY FCFP++ RR R+ NRRCRR CRR+VKSQ FYW VIVLVFLNTGVLTSEHY Q WLD FQN AN++FVVLFT+EML+KMYSLG+RCYFD+MFNRFD FVVI SILEIV I T MPPLGVSV RCARLLRVFKVTRYW+SLRNLVGSLLASM+SI SLLVLLFLFIVIF+LLGMQ+FGG+FNF KPRSNFD+F Q+L TVFQILTGEDWNE MY GI+SY S++ CLYYV+LFICGNYILLNVFLAIAVDNLADTG G++ S S + D+ T D ++KSE+ GD + + + T +N+E E+ +N S S + KIKPIP AS+FFIFGP N FR FCH+ICNHP+F N+VLVCI+VSSAMLAAEDPL A S RN ILNYFDY FTSVFTVEITLK F + C+ N L T A ++ + VVAVKSIGNIMLVTFLLEFMFAVIGVQLF GKF CND ++ C G +I Y+ D + + +R WIN PLNFDNVPN +LTLF STFEGWP +LY+SIDS+ ED+ +YN RP+V IFY+A+I+V+AFFM+NIFVGFVIVTFQQEGE+EYK CELDKNQRKCIEFALKA+PVRRYIPK+ F+YR+WW +TS+PFEY IF+ I++NTI L +KF+ QP Y +DYLNM+FTGVFTVEF+LKL A GFKNYF+D WNVFDFIIVLGSF+DI+ H+ + ISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLI+MLFFIYAVIGMQMFGKI N I N NFQTFPQA+L+LFRSATGEAWQ+IM C + A CD SD+ R +G D V CGS FAYP+FISFY+ICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKI+PPLGFGK CPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKT+GST DQLNEELR VIKKIWK TS K+LDQVVPPAG NDDVTVGKFYATFLIQEWFRRWK K+ EE K + Y Q KR S+MPFR GR SL+ P +EK S ++R S+ G+MM+ LQRVGS RR S++ S+ + + P S S+P ++ S +PT
Sbjct: 109 KPLNLTSLALAAQ--TNARKRPASRAQAAGSRPQRALFCLSLRNPLRKMCIGIVEWKPFEYLILITILGNCFALGSHTPYPDGDSNGTNSILEKVENVFIVIFTIECLLKIVALGFVMHPGAYLRNGWNILDFTIVCLGLLQPLLQRMLDRSGVDVKALRAFRVLRPLRLVSGLPSLQVVLNAIIRAMVPLLHIALLVIFVITMYAIVGLELFSGKLHATCYDIYTGEIMDNPTPCSLSRQGHICKFPFVCHDFRPNMTKAAIAERRSIVANMSADPYAFTGFIKLPERWPGPNYGITNFDNLAASMLTVFQCVTMEGWTNVLYWMNDSQGMEWPFLYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFAEDVQGYLDWIGAAEDLSDDEDNANRLDVKEKRFNLCGLCRRSQGGEEEDEDDSDRDDCGYR--TQSSQQKQYFFCFPIRGRRSRRLNRRCRRSCRRMVKSQTFYWTVIVLVFLNTGVLTSEHYGQPKWLDIFQNDANVVFVVLFTIEMLLKMYSLGVRCYFDYMFNRFDCFVVICSILEIVFIMTKLMPPLGVSVFRCARLLRVFKVTRYWNSLRNLVGSLLASMRSIASLLVLLFLFIVIFALLGMQIFGGRFNFLSLRKPRSNFDNFYQALTTVFQILTGEDWNEAMYMGIKSYSTQPFGSLV-CLYYVVLFICGNYILLNVFLAIAVDNLADTGQS------------------KGKQ----KSEATSEDGDDNTAGMD---IVKSED--GDSFNPAEEDGKSTFVTNSKNNENEEYVSIEERDNESESVYSDEHHGSGENFQPKIKPIPEASAFFIFGPRNPFRVFCHYICNHPYFNNVVLVCILVSSAMLAAEDPLKANSYRNIILNYFDYFFTSVFTVEITLK-------FGHHLCCK---NFASLSCSST--------------------------------ATSYQQSQRSQVVAVKSIGNIMLVTFLLEFMFAVIGVQLFAGKFHYCNDEARFYKEECAGPFIKYDSEDPSLPELVERRWINYPLNFDNVPNGLLTLFVASTFEGWPALLYQSIDSYAEDHGKVYNCRPVVVIFYVAFIVVVAFFMVNIFVGFVIVTFQQEGEQEYKGCELDKNQRKCIEFALKARPVRRYIPKERFQYRIWWFVTSQPFEYCIFIFILINTICLGMKFEGQPPVYADALDYLNMIFTGVFTVEFILKLTALGFKNYFNDLWNVFDFIIVLGSFVDIVLSHI------AENSKFISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLILMLFFIYAVIGMQMFGKIALNNPD--SAITVNANFQTFPQAVLILFRSATGEAWQDIMFSCAGETAYCDKQSDESRTA--------------VGATDRTV------------------------CGSAFAYPFFISFYIICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKISPPLGFGKLCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTEGSTPDQLNEELRAVIKKIWKHTSPKLLDQVVPPAGSNDDVTVGKFYATFLIQEWFRRWKLKKAEEHKHLPYGQHKRHSIMPFR--GR------SLMQPE-------EEKGGG---SSASDDKRQISLLGSMMHALQRVGSYRRSSSSPQSSPAPAEANGANTPAPPSPSKPTVIGSSGTPT 1727
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. TrEMBL
Match: A0A182J4Y3 (Voltage-dependent L-type calcium channel subunit alpha OS=Anopheles atroparvus OX=41427 PE=3 SV=1) HSP 1 Score: 1820.05 bits (4713), Expect = 0.000e+0 Identity = 1020/1687 (60.46%), Postives = 1225/1687 (72.61%), Query Frame = 1
Query: 970 RTPARSQSGNP---RPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY-SKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKA-KPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIA---------DESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLP---DAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDD-VTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLM---PFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVG 5967
+ P R P RP R LFCLT NP RK CI IVEWKPFEYLIL TIFANC ALA TP+P DSN+ N+ALEKIE +F+VIFT EC++K++A+GFI+HPG+YLRNGWN+LDF IV+IG+IST LS + + G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI+RAMVPL HIALL LFVIIIYAIIGLELFSGKLH +C+ ++ +M+ P PC G+ CD + +C+ W GPN GIT+FDNFGL+MLTVFQC+T+EGWT ++Y+I D++G SW W+YF+S++I+G+FFVMNL+LGVLSGEFSKER KAK RG +QK RE+ Q DED GYLDWI AEDI D E G + GK T+ + +Q +C K + + NRR RR CR+ VKSQAFYW++I+LVFLNTGVL +EHYRQ WLD FQ N+ FV LFT+EML+KMYSLG + YF +FNRFD FVVI SI E+V+ T MPPLGVSVLRC RLLRVFKVT+YW SL NLV SLL S++SI SLL+LLFLFIVIF+LLGMQ+FGGKFNF+ KPRSNFDSFVQSLLTVFQILTGEDWN VMYDGI++YG + +++ +Y++ILFICGNYILLNVFLAIAVDNLAD S EK EGEN E + E + + D+ +D + + S+E G + DE + T+ +T E ++ RR+SE+ K+ KPIP A+S IF P N+FR FCH++CNH FGNI+LVCIM SSAMLAAEDPL+A S RN+ILNYFDY FTSVFT+E+ LK+++YG +FH+GAFCRS+ N+LDLLVV S+IS ++ AISV+KILRVLRVLRPLRAINRAKGLK VVQCV+VAVK+IGNI+LVT LL+FMFAVIGVQL+ GKF SC+D SK C G Y+ Y + ++ K +R W N +FD+V AMLTLF VSTFEGWPG+LY SIDS +ED I+N RPIV+ +YI YII+IAFFM+NIFVGFVIVTFQ EGE+EYKNC+LDKNQR CIEFALKAKP+RRYIPK +Y+VWW +TS+PFEY+IF+LIM+NTI+L++KF +QP+ Y +V+D LN++FT VF +EF+ KLAAF FKNYF DAWNVFDFIIVLGSFIDI+Y VN + G +ISINFFRLFRVMRLVKLL+RGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQ+FGKI ++E I+RNNNFQTFPQA+LVLFRSATGEAWQ+IML C + CDA SD AG+ P CGS+ A+PYFISFY++CSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDP+AKGRIKHLDVVTLLRKI+PPLGFGK CPHR AC LV MNMPLNSDGTV+FNATLFA+VRT+LKIKT+G+ +D N ELR IK+IWKRT+ K+LDQVVPP G DD VTVGKFYATFLIQ++FRR+K KR E ++ Q+KR ++ RT L IS L D + PSH RR H++FG + + ++R G
Sbjct: 182 KKPTRRAGVKPQPDRPLRVLFCLTRTNPLRKLCIAIVEWKPFEYLILLTIFANCVALAVYTPFPNSDSNSTNAALEKIEYIFLVIFTAECMMKLIAYGFILHPGSYLRNGWNILDFTIVVIGMISTALSNLMKEGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILRAMVPLLHIALLVLFVIIIYAIIGLELFSGKLHKSCFHNETGEIMDDPHPCG---EDGFHCDTISP---EMVCR------YYWEGPNFGITNFDNFGLSMLTVFQCVTLEGWTDMLYYIEDAMGSSWQWVYFISMVILGAFFVMNLILGVLSGEFSKERTKAKNRGDFQKLREKQQNDEDFCGYLDWITQAEDIDPDNEASGLQEGKTKN---------------------TIELDSTDNLGEDGEVRQESWC-ARKRKSFERVNRRLRRACRKAVKSQAFYWLIIILVFLNTGVLATEHYRQPPWLDDFQENTNMFFVALFTMEMLLKMYSLGFQVYFASLFNRFDCFVVIGSIGEMVLTSTQIMPPLGVSVLRCVRLLRVFKVTKYWQSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFNSSVDKPRSNFDSFVQSLLTVFQILTGEDWNMVMYDGIQAYGGVASMGIIASIYFIILFICGNYILLNVFLAIAVDNLADADSLTTVEKDEGENPEEGDEKLSHEPTPTEHGDDGFMEHDKDNLDSDNDPMNMSDEYEGHDSESKIPVADDDEGYEEQDTQGETFDEPPTA-------------SARPRRLSELSVKKSKKPIPKANSLLIFSPTNRFRIFCHWLCNHSTFGNIILVCIMFSSAMLAAEDPLNANSERNQILNYFDYFFTSVFTIELLLKLVSYGFLFHDGAFCRSAFNLLDLLVVCVSLISMFFSSGAISVIKILRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLYKGKFFSCSDGSKMQESECHGTYLVYEDGNVDKPVSKERYWSRNRFHFDDVSKAMLTLFTVSTFEGWPGLLYVSIDSHEEDSGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLDKNQRNCIEFALKAKPIRRYIPKHRIQYKVWWFVTSQPFEYMIFILIMINTITLSMKFYRQPEIYTEVLDLLNLIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEVNVSKGMKGGSSIISINFFRLFRVMRLVKLLARGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAMDDE---TSIHRNNNFQTFPQAVLVLFRSATGEAWQDIMLDCSSRPGEVNCDAKSD---------------DAGS-----------PEG------------------CGSSIAFPYFISFYVLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLKIKTEGN-IDDANAELRTTIKQIWKRTNPKLLDQVVPPPGVDDEVTVGKFYATFLIQDYFRRFK-KRKENDNKLSSDQNKRRTMTLQAGLRTLHEAGPELKRAISGNLEEIG-----DDNPEPSH----RRNHTLFGNVWSSIRRPG 1763
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: cacna1db (calcium channel, voltage-dependent, L type, alpha 1D subunit, b [Source:ZFIN;Acc:ZDB-GENE-040525-3]) HSP 1 Score: 1612.43 bits (4174), Expect = 0.000e+0 Identity = 923/1608 (57.40%), Postives = 1107/1608 (68.84%), Query Frame = 1
Query: 934 TLSAQIASGG--------RKR-----TPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSE-----------GGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMM--ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFT-DAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVN------GTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAG 5658
T+S Q +G RKR + + S N RP RALFCLTL NP R+ CI +VEWKPF+ IL +IFANC ALA P+PE DSN+ N LE +E F++IFT E LKI+A+G +MH +Y+RNGWN+LDF+IVI+GL S VL +++ GG DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H+TCY + E PCS S G C + +CKD W GPN GIT+FDNF AMLTVFQCITMEGWT+++YW+ND++G PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + + +G + GK + + S +S + D+ + G S ++ FC RR CR VKS FYW+VI+LVFLNT ++SEHY Q WL Q+ AN + + +FT EMLIKMYSLG++ YF +FNRFD FVV I+E ++++ + M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD S N +E + N +I + R + + + + D DE R +R+SE+ KEK PIP S+FFIF N R CH + NH F N++LV IM+SS LAAEDP+ + S+RN IL YFDY FT++FTVEI LK+ +G H GAFCR+ N+LDLLVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF C D +K++ C+G YI YN D A V +R W N+ NFDNV AM+ LF VSTFEGWP +LYK+IDS +E+ IYN R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S FEY++FVLI+LNT+ LA++ Q + MD LNMVFTGVFTVE +LKL AF + YF DAWNVFD ++V+GS +DII V+ T N ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQ+FGKI + INRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP +CD+ SD YN P CGSNFA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ ++Q NEELR VIKKIWKRTS K+LDQVV G
Sbjct: 52 TMSGQSVAGSAPVGSLSQRKRQQYAKSKKQGSSTNSRPPRALFCLTLNNPIRRACISLVEWKPFDIFILLSIFANCVALAVYVPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNSYVRNGWNMLDFVIVIVGLFSVVLEFLTKEGDSSQSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCYMNGSRTLADEESAPCSLS-GHGRHCTVNGT-----LCKDG------WQGPNNGITNFDNFLFAMLTVFQCITMEGWTEVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEGDQEGKRNP----SMPTSETESVNTDNPNGEDDKARCCGPICRSWRRWNRFC---------------RRKCRAAVKSTTFYWLVILLVFLNTLTISSEHYNQPDWLTEVQDVANKVLLAMFTCEMLIKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETVTKRSTFDNFPQALLTVFQILTGEDWNTVMYDGIMAYGGPSSSGMVVCIYFIILFICGNYILLNVFLAIAVDNLADAESL----------------NTAQKEEEEQNKRRKKQSIKQADRNSHEVHDVAHHRHGSEDDEDEPEVPPGPRP--------------------------QRLSELTIKEKTPPIPEGSAFFIFSNTNPIRVSCHRLINHQIFTNLILVFIMLSSVSLAAEDPIRSYSARNIILGYFDYAFTAIFTVEILLKMTAFGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSSPEECKGTYILYNIGDNALPQVRERIWFNSDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNRENMGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNRYQYKFWYVVNSAGFEYVMFVLIILNTLCLAIQHHGQSHLFNYAMDILNMVFTGVFTVEMILKLVAFKPRGYFGDAWNVFDALVVIGSVVDIILSQVDVIESWTATAGNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDG---TSINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDSESD------YN---------------------PGEE----------------KTCGSNFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LEQANEELRAVIKKIWKRTSTKLLDQVVSRNG 1539 HSP 2 Score: 119.783 bits (299), Expect = 3.282e-26 Identity = 115/370 (31.08%), Postives = 172/370 (46.49%), Query Frame = 1
Query: 910 RPLNLAALTLSAQIASGGRKRTPARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR---WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
RP L+ LT+ +++TP P P+ A F + NP R C +++ + F LIL I + +LAA P R + N L + F IFT E +LK+ AFG +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y D SP C KG + Y DN R W + +FDN +AM+ +F T EGW ++Y DS + IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 791 RPQRLSELTI--------KEKTP-------PIPEGSAFFIFSNTNPIRVSCHRLINHQIFTNLILVFIMLSSVSLAAEDPI--RSYSARNIILGYFDYAFTAIFTVEILLKMTAFGAFLHKGAFCRNYFNLLDLLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCTDEAKSSPEEC-----KG--------TYILYNIGDNALPQVRERIWFNSDF---NFDNVLMAMMALFTVSTFEGWPALLYKAIDSNRENMGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1121
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: cacna1sb (calcium channel, voltage-dependent, L type, alpha 1S subunit, b [Source:ZFIN;Acc:ZDB-GENE-051227-1]) HSP 1 Score: 1457.2 bits (3771), Expect = 0.000e+0 Identity = 843/1728 (48.78%), Postives = 1101/1728 (63.72%), Query Frame = 1
Query: 982 RSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSE---------GGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSK-NDVMM----ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDG----KENGKESR--FKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFV--QSLLTVF-QILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRG-----------DRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMP-FRTHGRGSGP-LISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRP 6057
++ GNPRP R+LF TL+NPFRK C KIVEWKPFE +IL TIFANC ALA P PE D+N N+ LE +E +F+VIFT EC LKI+A+G + H GAYLRN WN+LDF+IV +GL + + ++ GG D+KALRAFRVLRPLRLVSG+PSLQVVMNSI++AM+PLF + LL F++ ++AI+GLEL+ K+H TCY + D++ E P PC+ + N G +C + C+ W GPN GIT FDNFG AMLTVFQCITME WT ++YW+ND+VG W WIYFV++I++GSFFV+NLVLGVLSGEFSKEREK + RG+YQK RE+ Q DED++GY++WI AE + D+E G K++ ES F + GL + + ++ +++ F LK VKS+ FYW+VI++VFLNT V+ EH+ QS FQ+ AN I + F EM KMY+ G+R YF +FNRFDFFVV ILEI+++ D M PLG+SV+RC RLLR F K K R F+ F L +F Q++TGE+W+ +MY+GI ++G +L +Y++IL++ GN+ILLNVFLAIAVDNL + S + +K++ E + + T EE KA + KT +K +E ++ + + + + +EE+ E + R ++++ KE + P+P ASSFFIFGP NKFRK CH N F N +L+ I++SS LAAED +D +S RN+IL Y D +FT+VFT+EI LK+ YG + H G+FCR++ NILDL+VV+ S++S + + AISV+KILRVLRVLRPLRA+NRAKGLK VVQCV VA+++IGNI+LVT LL FMFA IGVQL+ GKF SC D K T C+G ++ + + + +R+W+N+ NFDNVPNAML LF VSTFEGWP +LYK+IDS ED ++NNR S+F++ Y+I+IAFFM+NIFVGFVIVTF+++GE+E+KNCELDKNQR+C+++ALKA+P+R YIPK ++YRVW+L+TS FEY++F+LI+LNT SL L+ Q ++ D LN++FT +FT E ++KL AF K YF D WNVFDF+IV+GS +D++ V+ + G + +SI FFRLFRV+RL+KLL+R EGIR LLWTF+KSFQA P+VALLIVMLFFIYAVIGMQ+FGKI + EINRN NFQTFPQAIL+L+R+ TGE WQ +ML C+ +CD SD E Y CG+NFA YF+SF MIC FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF ++W+EYDPEA GRIKHLDVVTLLR+I PPLGFGK+CPHR+AC L+ MNMPLNSDGTV FNATLFALVRT+L IKT+G+ +Q NEELR++IK IWKRTS K+LDQV+PP G D+VTVGKFYATFLIQE FR++ KR EE G ++ + RT + P L IS L+ DE D+ G RRT +FG G ++ P++ + ++ P S SRP
Sbjct: 27 QATGGNPRPARSLFFFTLKNPFRKACTKIVEWKPFEIIILLTIFANCVALAVFLPMPEEDTNYTNTTLESLEYIFLVIFTLECFLKIIAYGLLFHEGAYLRNCWNILDFVIVFMGLFTLAVDTINAIAGTPTEKGGGFDMKALRAFRVLRPLRLVSGVPSLQVVMNSILKAMIPLFQVVLLVFFLVTLFAIMGLELYKCKMHKTCYYEGTDIIALRENEVPSPCAQAGN-GRRCTINGTE-----CRGG------WPGPNFGITHFDNFGFAMLTVFQCITMESWTNVLYWVNDAVGNEWAWIYFVTMILLGSFFVLNLVLGVLSGEFSKEREKCRSRGEYQKLRERQQMDEDLKGYMEWITHAEVLDADQEGQGLLPLKDSDSESEILFAIEGLNRIA---------------------YYYRLARRWNRVFRLKCAV--------------WVKSRMFYWLVILVVFLNTLVIACEHHPQSESATRFQDVANDILLTCFAFEMFAKMYAFGLRAYFMSVFNRFDFFVVTVGILEIILVAADVMTPLGISVMRCIRLLR----------------------------------------------------FVKITKLRFFFNRFCVYNRLYHIFIQVITGEEWDTIMYNGIMAHGGPQSPGILVSIYFIILYVVGNFILLNVFLAIAVDNLTEAESLSSAQKEKEEEKARKKTAPPHEEEKAKLVKS-----KHKTEGMPTTAKLKVDEFESNVKE---------VKDPFPPADFPGDDEEEEPEIPISPRPRPMADLQLKETVVPMPEASSFFIFGPENKFRKLCHRAINATPFTNFILLLILLSSISLAAEDAIDPKSFRNKILAYADIVFTTVFTIEIVLKMTVYGAILHTGSFCRNAFNILDLIVVVVSLLSMGLESSAISVIKILRVLRVLRPLRALNRAKGLKHVVQCVFVAIQTIGNIILVTMLLNFMFACIGVQLYKGKFYSCTDPLKLTEEECQGTFVKHVRNSLHDKEIGQRQWVNSDFNFDNVPNAMLALFTVSTFEGWPELLYKAIDSDAEDRGPVFNNRMDTSLFFVIYLIIIAFFMMNIFVGFVIVTFREQGEQEFKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYRVWYLVTSCYFEYLMFLLIILNTCSLGLQHCNQSDHITKLADTLNVIFTVLFTFEMIVKLIAFKAKGYFGDPWNVFDFLIVIGSIVDVVLSQVDAALESSGGLYCLHGCTYEENARVSITFFRLFRVLRLIKLLNRSEGIRNLLWTFIKSFQAFPHVALLIVMLFFIYAVIGMQVFGKIALVDG---TEINRNANFQTFPQAILILYRTVTGEGWQKLMLACMSGKLCDPRSDYAPGEEYT-------------------------------------------CGTNFAVFYFLSFNMICGFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKKIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCPHRSACRRLISMNMPLNSDGTVTFNATLFALVRTDLSIKTEGN-FEQANEELRLIIKSIWKRTSMKLLDQVIPPIGEDEVTVGKFYATFLIQEHFRKF-MKRQEEYYGYRPTKKSAAEIQAGLRTIEEEAAPELHRAISGDLIAE---DEMDRALEGGEDGIYRRTGGLFG---------GLNSDPFSSEPNSPTAAQTSNRPLQFSESRP 1581
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: cacna1da (calcium channel, voltage-dependent, L type, alpha 1D subunit, a [Source:ZFIN;Acc:ZDB-GENE-030616-135]) HSP 1 Score: 988.408 bits (2554), Expect = 0.000e+0 Identity = 546/900 (60.67%), Postives = 658/900 (73.11%), Query Frame = 1
Query: 3301 VSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDK---DYLPSH-LGAERRTHSIFGTMMNVLQRVGSTRRDSN 5988
+SE++ KEKI PIP S+FFIF N R CH + NH F N++LV IM+SSA LAAEDP+ S+RN IL YFDY FT++FTVEI LK+ TYG H GAFCR+ N+LDLLVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF CND +K++ C+G YI Y + D+ + + KR W N+ NFDNV AM+ LF VSTFEGWP +LYK+IDS KE++ IYN R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S FEYI+FVLIMLNT+ LA++ Q Q + VMD LNM FT VFTVE +LKL AF ++YF+DAWN FD +IV+GS +DI VN T ++ R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQ+FGK+ + +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C+ +CD SD YN P CGS+FA YFI+FYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ ++Q NEELR VIKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQ++FR++K+++ E G+ +Q+ + + + I P + CD +D+ D++P RR +FG MN + G RR S
Sbjct: 760 ISELVKKEKITPIPEGSAFFIFSNTNPIRVACHKLINHHIFTNLILVFIMLSSASLAAEDPIRNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYILYKDGDVNQPTLQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAVQHYGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSAR----ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESD------YN---------------------PGEEMT----------------CGSSFAIVYFITFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LEQANEELRAVIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEEGLVGVHPAQNNTAIAL------QAGLRTLHDIGPEIRRAISCDLQDEELVDFMPEEDEEIYRRNGGLFGNHMNHIN--GDHRRGSG 1600 HSP 2 Score: 710.679 bits (1833), Expect = 0.000e+0 Identity = 403/720 (55.97%), Postives = 496/720 (68.89%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSE------------------------GGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR-WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGL-----------CKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXX--------XXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLAD 2997
++ + S N RPQRALFCL L NP R+ CI +VEWKPF+ IL IFANC ALA P+PE DSN+ N LE +E F++IFT E LKI+A+G +MH AY+RNGWN+LDF+IV+IGL S VL +++ GG DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H+TC+ + + P PC+ + G C N E W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND++GM PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI D E + +++ K +R L L +SSE ++ ++ E E G + ++ C PL + + R RR CR VKS FYW+VI+LVFLNT ++SEHY Q +WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV I E ++++ + M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQ+FGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD
Sbjct: 44 KSKKQGSSANTRPQRALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYIPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKDGGQEDEGVEIPLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVEMISEDEPAPCAVN-------------GHGRTCTINGTECREGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPDNEEEEEDS-KRNRVTLADLMDKKKKGFSFFSQSSETHASVPASETESVNTENEKG----EDEKATCCGPLCQKISKSKFSRRWRRWNRFCRRKCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNVVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLAD 745 HSP 3 Score: 124.79 bits (312), Expect = 1.244e-27 Identity = 111/366 (30.33%), Postives = 170/366 (46.45%), Query Frame = 1
Query: 919 NLAALTLSAQIASGGRKRTP--ARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
NLA ++ SG R + + P P+ A F + NP R C K++ F LIL I + +LAA P R+ + N L + F IFT E VLK+ +G +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y ND SP C + Y+ D + + W + +FDN +AM+ +F T EGW ++Y DS ++ IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 742 NLADEEDEPEVPSGPRPAISELVKKEKITPIPEGSAFFIFSNTNPIRVACHKLINHHIFTNLILVFIMLSSASLAAEDPI--RNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCNDEAKSSPEECKGTYIL-YKDGDVNQPTL---------QKRHWHNSDF---NFDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1086 HSP 4 Score: 95.9005 bits (237), Expect = 7.409e-19 Identity = 72/256 (28.12%), Postives = 126/256 (49.22%), Query Frame = 1
Query: 4237 EEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSF--RYRVW---------WLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
E E N E +K + E A P+ + I K F R+R W + S PF +++ +L+ LNT++++ + QP QV D N V +FT E L+K+ + G + YF +N FD +V G + I + + + I+ FR R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQA+L +F+ TGE W +M
Sbjct: 458 ETESVNTENEKGED---EKATCCGPLCQKISKSKFSRRWRRWNRFCRRKCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSP-------LGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKR----STFDNFPQALLTVFQILTGEDWNVVM 699 HSP 5 Score: 91.6633 bits (226), Expect = 1.258e-17 Identity = 68/252 (26.98%), Postives = 138/252 (54.76%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQ---TDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMYDGI-------RSYGNLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ VL+ LNT L +HY QS + + N+ F +FT+EM++K+ + R YF +N FD +V+ S+++I + + T+ + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R +NF +F Q++L +F+ TGE W E+M + S N G+ S + +Y++ ++ ++++N+F+A+ +DN
Sbjct: 1113 VVNSTGFEYIMFVLIMLNTLCLAVQHYGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESDYNPGEEMTCGSSFAIVYFITFYMLCAFLIINLFVAVIMDNF 1364 HSP 6 Score: 89.3521 bits (220), Expect = 6.582e-17 Identity = 74/316 (23.42%), Postives = 137/316 (43.35%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKA----LRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWI----------------NDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEY++ I N LA S T N ++ + + F +FT E VLK++AF P Y + WN D LIV+ ++ +++++ + R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+ M++ T +N+ N N F F A+L +F+C T E W +IM + G S+ +YF++ ++ +F ++NL + V+ F
Sbjct: 1103 KNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAVQH---YGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAF----KPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIF-GKV---------AMVD-----GTQINR------------------NNN--------------FQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESDYNPGEEMTCGSSFAIVYFITFYMLCAFLIINLFVAVIMDNF 1364 HSP 7 Score: 78.1814 bits (191), Expect = 1.534e-13 Identity = 63/269 (23.42%), Postives = 117/269 (43.49%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINF------------------FRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF---------------------------GKITTENEKEMKEINRN-----NNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
L+ +PF+ I + I N ++LA+ + ++ + F +FT+E LK+ A+G Y + WN+ DF+IV+ ++ + + T + + D + I R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G+ T N E +E NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 76 LVEWKPFDIFILIAIFANCMALAVYIPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVL--TKDGGQEDEGVEIPLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVEMISEDEPAPCAVNGHGRTCTINGTECREGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDV-LYWMNDAM 341 HSP 8 Score: 78.1814 bits (191), Expect = 1.755e-13 Identity = 86/370 (23.24%), Postives = 157/370 (42.43%), Query Frame = 1
Query: 4009 FDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQS----------FRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQR----YEQVMDYLNMVFTGVFTVEFLLKLAAFG--------FKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF---------------------------GKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
FDN P A+LT+F + T E W V+Y I + Y G ++ IV I++I I + ++N+F+ + E +E E+ R I +K + + IP+ S R LI F +I V IML++ SLA + P R ++ Y + FT +FTVE +LK+ +G +NYF N+ D ++V S + + + + R+ RV+R ++ ++R +G++ ++ + + + + ++ +L F++A IG+Q+F G + ++ N + NF A++ LF +T E W ++
Sbjct: 676 FDNFPQALLTVFQILTGEDWNVVMYDGIMA----YGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADEEDEP----EVPSGPRPAISELVKKEKITP-IPEGSAFFIFSNTNPIRVACHKLINHHIFTNLILVFIMLSSASLAA---EDPIRNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYF----NLLDLLVVGVSLVSF----------GIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYILYKDGDVNQPTLQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALL 1019 HSP 9 Score: 77.7962 bits (190), Expect = 2.129e-13 Identity = 78/300 (26.00%), Postives = 125/300 (41.67%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKG----------------------------LKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQS----CNDVSKNTHISC----RGQYIYYNEADIAKVFVNKREWINNP----LNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
+ F NN R+ C + F +L+ I + LA P D +S N L +Y F +FT+E LK+I YGLV H A+ R+ N+LD ++V+ + S + + ++ V PL A A G L+ V+ ++ A+ + +I L+ + ++A+IG++LF GK + +S++ C G+ N + RE + P NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 59 ALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYIPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVL--EVLTKDGGQEDEGVEIPLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVEMISEDEPAPCAVNGHGRTCTINGTEC-------REGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVY 349
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: cacna1da (calcium channel, voltage-dependent, L type, alpha 1D subunit, a [Source:ZFIN;Acc:ZDB-GENE-030616-135]) HSP 1 Score: 987.252 bits (2551), Expect = 0.000e+0 Identity = 544/899 (60.51%), Postives = 658/899 (73.19%), Query Frame = 1
Query: 3301 VSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDK---DYLPSH-LGAERRTHSIFGTMMNVLQRVGSTRRDS 5985
+SE++ KEKI PIP S+FFIF N R CH + NH F N++LV IM+SSA LAAEDP+ S+RN IL YFDY FT++FTVEI LK+ TYG H GAFCR+ N+LDLLVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF CND +K++ C+G YI Y + D+ + + KR W N+ NFDNV AM+ LF VSTFEGWP +LYK+IDS KE++ IYN R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S FEYI+FVLIMLNT+ LA++ Q Q + VMD LNM FT VFTVE +LKL AF + YF DAWNVFD ++V+GS +DI+ ++ T ++ R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQ+FGK+ + +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C+ +CD SD YN P CGS+FA YFI+FYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ ++Q NEELR VIKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQ++FR++K+++ E G+ +Q+ + + + I P + CD +D+ D++P RR +FG MN + G RR S
Sbjct: 723 ISELVKKEKITPIPEGSAFFIFSNTNPIRVACHKLINHHIFTNLILVFIMLSSASLAAEDPIRNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYILYKDGDVNQPTLQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAVQHYGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRGYFGDAWNVFDALVVIGSIVDIVLSEIDNTEDSAR----ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESD------YN---------------------PGEEMT----------------CGSSFAIVYFITFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LEQANEELRAVIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEEGLVGVHPAQNNTAIAL------QAGLRTLHDIGPEIRRAISCDLQDEELVDFMPEEDEEIYRRNGGLFGNHMNHIN--GDHRRGS 1562 HSP 2 Score: 701.049 bits (1808), Expect = 0.000e+0 Identity = 393/703 (55.90%), Postives = 478/703 (67.99%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMM--ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR-WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIG-----------------------AAEDISDDEENDGKENGKESRFKLCG-LCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLAD 2997
++ + S N RPQRALFCL L NP R+ CI +VEWKPF+ IL IFANC ALA P+PE DSN+ N LE +E F++IFT E LKI+A+G +MH AY+RNGWN+LDF+IVI +T GG DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H+TC+ M+ + P PC+ +G C N E W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND++GM PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI A+E S + EN E G++ + CG LC+ ++ ++ FC RR CR VKS FYW+VI+LVFLNT ++SEHY Q +WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV I E ++++ + M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQ+FGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD
Sbjct: 54 KSKKQGSSANTRPQRALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYIPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVIPLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVGSEMISEDEPAPCAV-------------NGHGRTCTINGTECREGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPDNEEEEEDSKRNPSVPASETESVNTEN---EKGEDEKATCCGPLCQKI-----------------SKSKFSRRWRRWNRFC---------------RRKCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNVVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLAD 708 HSP 3 Score: 124.405 bits (311), Expect = 1.573e-27 Identity = 111/366 (30.33%), Postives = 170/366 (46.45%), Query Frame = 1
Query: 919 NLAALTLSAQIASGGRKRTP--ARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
NLA ++ SG R + + P P+ A F + NP R C K++ F LIL I + +LAA P R+ + N L + F IFT E VLK+ +G +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y ND SP C + Y+ D + + W + +FDN +AM+ +F T EGW ++Y DS ++ IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 705 NLADEEDEPEVPSGPRPAISELVKKEKITPIPEGSAFFIFSNTNPIRVACHKLINHHIFTNLILVFIMLSSASLAAEDPI--RNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCNDEAKSSPEECKGTYIL-YKDGDVNQPTL---------QKRHWHNSDF---NFDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1049 HSP 4 Score: 96.2857 bits (238), Expect = 5.173e-19 Identity = 72/256 (28.12%), Postives = 126/256 (49.22%), Query Frame = 1
Query: 4237 EEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSF--RYRVW---------WLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
E E N E +K + E A P+ + I K F R+R W + S PF +++ +L+ LNT++++ + QP QV D N V +FT E L+K+ + G + YF +N FD +V G + I + + + I+ FR R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQA+L +F+ TGE W +M
Sbjct: 421 ETESVNTENEKGED---EKATCCGPLCQKISKSKFSRRWRRWNRFCRRKCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSP-------LGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKR----STFDNFPQALLTVFQILTGEDWNVVM 662 HSP 5 Score: 93.9745 bits (232), Expect = 2.597e-18 Identity = 77/316 (24.37%), Postives = 138/316 (43.67%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKA----LRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWI----------------NDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEY++ I N LA S T N ++ + + F +FT E VLK++AF P Y + WN+ D L+VI ++ VLS++ + R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+ M++ T +N+ N N F F A+L +F+C T E W +IM + G S+ +YF++ ++ +F ++NL + V+ F
Sbjct: 1066 KNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAVQH---YGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAF----KPRGYFGDAWNVFDALVVIGSIVDIVLSEIDNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIF-GKV---------AMVD-----GTQINR------------------NNN--------------FQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESDYNPGEEMTCGSSFAIVYFITFYMLCAFLIINLFVAVIMDNF 1327 HSP 6 Score: 93.2041 bits (230), Expect = 4.193e-18 Identity = 72/252 (28.57%), Postives = 139/252 (55.16%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQ---TDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMYDGI-------RSYGNLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ VL+ LNT L +HY QS + + N+ F +FT+EM++K+ + R YF +N FD VVI SI++IV+ + T+ + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R +NF +F Q++L +F+ TGE W E+M + S N G+ S + +Y++ ++ ++++N+F+A+ +DN
Sbjct: 1076 VVNSTGFEYIMFVLIMLNTLCLAVQHYGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRGYFGDAWNVFDALVVIGSIVDIVLSEIDNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESDYNPGEEMTCGSSFAIVYFITFYMLCAFLIINLFVAVIMDNF 1327 HSP 7 Score: 80.4925 bits (197), Expect = 3.042e-14 Identity = 77/279 (27.60%), Postives = 124/279 (44.44%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNK------------REWINNP----LNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
+ F NN R+ C + F +L+ I + LA P D +S N L +Y F +FT+E LK+I YGLV H A+ R+ N+LD ++V+ + + + ++ LR R LR + G+ + + +K++ ++ + L+ F ++A+IG++LF GK + + + IS E + A VN RE + P NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 69 ALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYIPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVI-PLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVGSEMIS---------EDEPAPCAVNGHGRTCTINGTECREGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVY 337 HSP 8 Score: 79.337 bits (194), Expect = 8.338e-14 Identity = 62/254 (24.41%), Postives = 112/254 (44.09%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGD-RLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-----------------------------GKITTENEKEMKEINRN-----NNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
L+ +PF+ I + I N ++LA+ + ++ + F +FT+E LK+ A+G Y + WN+ DF+IV+ + + H G + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G+ T N E +E NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 86 LVEWKPFDIFILIAIFANCMALAVYIPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVIP---------LAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVGSEMISEDEPAPCAVNGHGRTCTINGTECREGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDV-LYWMNDAM 329 HSP 9 Score: 78.5666 bits (192), Expect = 1.269e-13 Identity = 86/370 (23.24%), Postives = 157/370 (42.43%), Query Frame = 1
Query: 4009 FDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQS----------FRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQR----YEQVMDYLNMVFTGVFTVEFLLKLAAFG--------FKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF---------------------------GKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
FDN P A+LT+F + T E W V+Y I + Y G ++ IV I++I I + ++N+F+ + E +E E+ R I +K + + IP+ S R LI F +I V IML++ SLA + P R ++ Y + FT +FTVE +LK+ +G +NYF N+ D ++V S + + + + R+ RV+R ++ ++R +G++ ++ + + + + ++ +L F++A IG+Q+F G + ++ N + NF A++ LF +T E W ++
Sbjct: 639 FDNFPQALLTVFQILTGEDWNVVMYDGIMA----YGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADEEDEP----EVPSGPRPAISELVKKEKITP-IPEGSAFFIFSNTNPIRVACHKLINHHIFTNLILVFIMLSSASLAA---EDPIRNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYF----NLLDLLVVGVSLVSF----------GIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYILYKDGDVNQPTLQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALL 982
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Cavefish
Match: cacna1da (calcium channel, voltage-dependent, L type, alpha 1D subunit, a [Source:ZFIN;Acc:ZDB-GENE-030616-135]) HSP 1 Score: 983.786 bits (2542), Expect = 0.000e+0 Identity = 544/899 (60.51%), Postives = 657/899 (73.08%), Query Frame = 1
Query: 3301 VSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDK---DYLPSH-LGAERRTHSIFGTMMNVLQRVGSTRRDS 5985
+SE++ KEKI PIP S+FFIF N R CH + NH F N++LV IM+SSA LAAEDP+ S+RN +L Y DY+FTS+FT EI LK+ TYG H GAFCR+ N+LDLLVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF CND +K++ C+G YI Y + D+ + + KR W N+ NFDNV AM+ LF VSTFEGWP +LYK+IDS KE++ IYN R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S FEYI+FVLIMLNT+ LA++ Q Q + VMD LNM FT VFTVE +LKL AF ++YF+DAWN FD +IV+GS +DI VN T ++ R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQ+FGK+ + +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C+ +CD SD YN P CGS+FA YFI+FYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ ++Q NEELR VIKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQ++FR++K+++ E G+ +Q+ + + + I P + CD +D+ D++P RR +FG MN + G RR S
Sbjct: 737 ISELVKKEKITPIPEGSAFFIFSNTNPIRVACHKLINHHIFTNLILVFIMLSSASLAAEDPIRNFSARNIVLGYADYVFTSMFTFEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYILYKDGDVNQPTLQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAVQHYGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSAR----ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDG---TQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESD------YN---------------------PGEEMT----------------CGSSFAIVYFITFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LEQANEELRAVIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEEGLVGVHPAQNNTAIAL------QAGLRTLHDIGPEIRRAISCDLQDEELVDFMPEEDEEIYRRNGGLFGNHMNHIN--GDHRRGS 1576 HSP 2 Score: 696.812 bits (1797), Expect = 0.000e+0 Identity = 405/712 (56.88%), Postives = 498/712 (69.94%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTIN---------SALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSE------------------------GGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMM--ESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSR-WSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLAD 2997
++ + S N RPQRALFCL L NP R+ CI +VEWKPF+ IL IFANC ALA P+PE DSN+ N S +E +E F++IFT E LKI+A+G +MH AY+RNGWN+LDF+IV+IGL S VL +++ GG DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H+TC+ M+ + P PC+ + G C N E W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND++GM PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI D E + +++ + +SE ++ ++ E E G + ++ C PL RR R+WNR CRR CR VKS FYW+VI+LVFLNT ++SEHY Q +WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV I E ++++ + M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQ+FGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD
Sbjct: 44 KSKKQGSSANTRPQRALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYIPFPEDDSNSTNHDLNCPSPQSIIETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKDGGQEDEGVEIPLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVGSEMISEDEPAPCAVN-------------GHGRTCTINGTECREGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPDNEEEEEDSKRNPS------VPASE---------TESVNTENEKG----EDEKATCCGPL-CRRWRRWNRFCRRKCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNVVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLAD 722 HSP 3 Score: 123.635 bits (309), Expect = 2.566e-27 Identity = 111/366 (30.33%), Postives = 171/366 (46.72%), Query Frame = 1
Query: 919 NLAALTLSAQIASGGRKRTP--ARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
NLA ++ SG R + + P P+ A F + NP R C K++ F LIL I + +LAA P R+ + N L + VF +FT E VLK+ +G +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y ND SP C + Y+ D + + W + +FDN +AM+ +F T EGW ++Y DS ++ IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 719 NLADEEDEPEVPSGPRPAISELVKKEKITPIPEGSAFFIFSNTNPIRVACHKLINHHIFTNLILVFIMLSSASLAAEDPI--RNFSARNIVLGYADYVFTSMFTFEIVLKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCNDEAKSSPEECKGTYIL-YKDGDVNQPTL---------QKRHWHNSDF---NFDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1063 HSP 4 Score: 92.8189 bits (229), Expect = 6.161e-18 Identity = 66/251 (26.29%), Postives = 122/251 (48.61%), Query Frame = 1
Query: 4219 TFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
T ++GE+E C C + + R+ R + + S PF +++ +L+ LNT++++ + QP QV D N V +FT E L+K+ + G + YF +N FD +V G + I + + + I+ FR R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQA+L +F+ TGE W +M
Sbjct: 450 TENEKGEDEKATC--------CGPLCRRWRRWNRFC-----RRKCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDVANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSP-------LGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKR----STFDNFPQALLTVFQILTGEDWNVVM 676 HSP 5 Score: 92.0485 bits (227), Expect = 1.157e-17 Identity = 68/252 (26.98%), Postives = 138/252 (54.76%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQ---TDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMYDGI-------RSYGNLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ VL+ LNT L +HY QS + + N+ F +FT+EM++K+ + R YF +N FD +V+ S+++I + + T+ + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R +NF +F Q++L +F+ TGE W E+M + S N G+ S + +Y++ ++ ++++N+F+A+ +DN
Sbjct: 1090 VVNSTGFEYIMFVLIMLNTLCLAVQHYGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESDYNPGEEMTCGSSFAIVYFITFYMLCAFLIINLFVAVIMDNF 1341 HSP 6 Score: 89.3521 bits (220), Expect = 6.642e-17 Identity = 74/316 (23.42%), Postives = 137/316 (43.35%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKA----LRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWI----------------NDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEY++ I N LA S T N ++ + + F +FT E VLK++AF P Y + WN D LIV+ ++ +++++ + R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+ M++ T +N+ N N F F A+L +F+C T E W +IM + G S+ +YF++ ++ +F ++NL + V+ F
Sbjct: 1080 KNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAVQH---YGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAF----KPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIF-GKV---------AMVD-----GTQINR------------------NNN--------------FQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESDYNPGEEMTCGSSFAIVYFITFYMLCAFLIINLFVAVIMDNF 1341 HSP 7 Score: 77.0258 bits (188), Expect = 3.966e-13 Identity = 87/370 (23.51%), Postives = 157/370 (42.43%), Query Frame = 1
Query: 4009 FDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQS----------FRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQR----YEQVMDYLNMVFTGVFTVEFLLKLAAFG--------FKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF---------------------------GKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
FDN P A+LT+F + T E W V+Y I + Y G ++ IV I++I I + ++N+F+ + E +E E+ R I +K + + IP+ S R LI F +I V IML++ SLA + P R V+ Y + VFT +FT E +LK+ +G +NYF N+ D ++V S + + + + R+ RV+R ++ ++R +G++ ++ + + + + ++ +L F++A IG+Q+F G + ++ N + NF A++ LF +T E W ++
Sbjct: 653 FDNFPQALLTVFQILTGEDWNVVMYDGIMA----YGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADEEDEP----EVPSGPRPAISELVKKEKITP-IPEGSAFFIFSNTNPIRVACHKLINHHIFTNLILVFIMLSSASLAA---EDPIRNFSARNIVLGYADYVFTSMFTFEIVLKMTTYGAFLHKGAFCRNYF----NLLDLLVVGVSLVSF----------GIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTYILYKDGDVNQPTLQKRHWHNSDFNFDNVLMAMMALFTVSTFEGWPALL 996 HSP 8 Score: 76.6406 bits (187), Expect = 4.975e-13 Identity = 64/280 (22.86%), Postives = 119/280 (42.50%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLAL------------KFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINF------------------FRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-----------------------------GKITTENEKEMKEINRN-----NNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
L+ +PF+ I + I N ++LA+ D + +++ + F +FT+E LK+ A+G Y + WN+ DF+IV+ ++ + + T + + D + I R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G+ T N E +E NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 76 LVEWKPFDIFILIAIFANCMALAVYIPFPEDDSNSTNHDLNCPSPQSIIETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVL--TKDGGQEDEGVEIPLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVGSEMISEDEPAPCAVNGHGRTCTINGTECREGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDV-LYWMNDAM 352 HSP 9 Score: 72.0182 bits (175), Expect = 1.339e-11 Identity = 81/313 (25.88%), Postives = 126/313 (40.26%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILN---------YFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKG----------------------------LKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNK------------REWINNP----LNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
+ F NN R+ C + F +L+ I + LA P D +S N LN +Y F +FT+E LK+I YGLV H A+ R+ N+LD ++V+ + S + + ++ V PL A A G L+ V+ ++ A+ + +I L+ + ++A+IG++LF GK + + + IS E + A VN RE + P NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 59 ALFCLNLNNPIRRACISLVEWKPFDIFILIAIFANCMALAVYIPFPEDDSNSTNHDLNCPSPQSIIETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVL--EVLTKDGGQEDEGVEIPLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVGSEMIS---------EDEPAPCAVNGHGRTCTINGTECREGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVY 360
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005302.1 (pep scaffold:Pmarinus_7.0:GL483978:134:5921:-1 gene:ENSPMAG00000004828.1 transcript:ENSPMAT00000005302.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 463.766 bits (1192), Expect = 6.590e-149 Identity = 233/346 (67.34%), Postives = 262/346 (75.72%), Query Frame = 1
Query: 4627 NGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGND 5664
+ +N+R ISI FFRLFRV+RLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI ++ + INRNNNFQTFPQA+L+LFR ATGEAWQ+IML C+P CD +D E ++ CGS+FA YF+SFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKH+DVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT+LKIKTDG+ ++Q NEELR VIKKIWKRT+ K+LDQVVPPAG D
Sbjct: 9 SAAEDNNR----ISITFFRLFRVLRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMQDGSQ---INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGRRCDPDADASVGEEFS-------------------------------------------CGSSFAIFYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHVDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTSLKIKTDGN-LEQANEELRAVIKKIWKRTNMKLLDQVVPPAGGD 303 HSP 2 Score: 52.7582 bits (125), Expect = 6.145e-7 Identity = 39/154 (25.32%), Postives = 81/154 (52.60%), Query Frame = 1
Query: 2563 LGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSN-FDSFVQSLLTVFQILTGEDWNEVMY----------DGIRSYG-NLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDN 2988
+ ++ R R+LR+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R+N F +F Q++L +F+ TGE W ++M D S G S + Y+V ++ ++++N+F+A+ +DN
Sbjct: 17 ISITFFRLFRVLRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMQDGSQINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGRRCDPDADASVGEEFSCGSSFAIFYFVSFYMLCAFLIINLFVAVIMDN 170
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007697.1 (pep scaffold:Pmarinus_7.0:GL478030:18311:55165:1 gene:ENSPMAG00000006953.1 transcript:ENSPMAT00000007697.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 301.597 bits (771), Expect = 9.738e-89 Identity = 201/358 (56.15%), Postives = 246/358 (68.72%), Query Frame = 1
Query: 1963 QKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGK-ESRFKLCGLCK---------SSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
QK RE+ Q +ED++GYLDWI AEDI + E++ +GK SR L L S SD + TE H ++ + C +RR R+WNR CRR R VKS FYWVVI+LVFLNT + SEHY Q WL Q+ AN + + +FT+EML KMYSLG++ YF +FNRFD FVV I+E ++++ M PLG+SVLRC RLLR+FKVT+YW++L NLV SLL SM+SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F QSLLTVFQILTGEDWN VMYDGI +YG + ML C+Y++ILFICGN IL+NVFLAIAVDNLAD S
Sbjct: 1 QKLREKQQLEEDLKGYLDWIMQAEDIDPENEDETGGDGKPRSRITLADLTDKKKGRFAWFSHSNETHASIPASDADSVNTENTGHEAES---LCCCVRLARRWRRWNRFCRRKTRLTVKSTGFYWVVIILVFLNTLTIASEHYNQPDWLTQVQDIANKVLLAMFTVEMLTKMYSLGLQAYFVSLFNRFDCFVVFGGIIETILVEFGVMSPLGISVLRCVRLLRIFKVTKYWAALSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQSLLTVFQILTGEDWNAVMYDGIMAYGGPSSTGMLVCIYFIILFICGNCILVNVFLAIAVDNLADAES 355 HSP 2 Score: 154.451 bits (389), Expect = 8.304e-39 Identity = 94/157 (59.87%), Postives = 116/157 (73.89%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLK 3765
RR+S++ KEK+ PIP S+FFIF N R CH + +H F N++L IM+SS LAAEDP+ S RN IL YFDY FT++FTVEI LK+ +YG H G+FCR+ N+LDLLVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK
Sbjct: 424 RRLSDLNLKEKVVPIPEGSAFFIFSSTNPVRVCCHRLIHHHIFTNLILAMIMLSSVSLAAEDPIRNHSFRNNILGYFDYAFTAIFTVEILLKMTSYGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLK 580 HSP 3 Score: 90.8929 bits (224), Expect = 1.764e-18 Identity = 62/230 (26.96%), Postives = 114/230 (49.57%), Query Frame = 1
Query: 4282 CIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
C+ A + + R+ R + + S F +++ +L+ LNT+++A + QP QV D N V +FTVE L K+ + G + YF +N FD +V G I+ I + + I+ R R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQ++L +F+ TGE W +M
Sbjct: 93 CVRLARRWRRWNRFC-----RRKTRLTVKSTGFYWVVIILVFLNTLTIASEHYNQPDWLTQVQDIANKVLLAMFTVEMLTKMYSLGLQAYFVSLFNRFDCFVVFGGIIETILVEFGVMSP-------LGISVLRCVRLLRIFKVTKYWAALSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKR----STFDNFPQSLLTVFQILTGEDWNAVM 306 HSP 4 Score: 83.1889 bits (204), Expect = 4.540e-16 Identity = 54/149 (36.24%), Postives = 79/149 (53.02%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQV 1443
P P+ A F + NP R C +++ F LIL I + +LAA P R+ + N+ L + F IFT E +LK+ ++G +H G++ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+V
Sbjct: 437 PIPEGSAFFIFSSTNPVRVCCHRLIHHHIFTNLILAMIMLSSVSLAAEDPI--RNHSFRNNILGYFDYAFTAIFTVEILLKMTSYGAFLHKGSFCRNYFNLLDLLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKV 581 HSP 5 Score: 55.0694 bits (131), Expect = 2.589e-7 Identity = 73/309 (23.62%), Postives = 133/309 (43.04%), Query Frame = 1
Query: 1024 CLTLRNPFRK---FCIK----IVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIM------YWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGV 1908
C+ L +R+ FC + V+ F ++++ +F N +A+ Y + D + + V + +FT E + K+ + G AY + +N D +V G+I T+L + P + LR R+LR ++ +L ++ S++ +M + + LL III++++G++LF GK + ++ +T R ++FDNF ++LTVFQ +T E W +M Y S GM IYF+ L I G+ ++N+ L +
Sbjct: 93 CVRLARRWRRWNRFCRRKTRLTVKSTGFYWVVIILVFLNTLTIASEH-YNQPD--WLTQVQDIANKVLLAMFTVEMLTKMYSLGL----QAYFVSLFNRFDCFVVFGGIIETILVEFGVMSPLGISVLRCVRLLRIFKVTKYWAALSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF----------------------------------------DETQTKR--------STFDNFPQSLLTVFQILTGEDWNAVMYDGIMAYGGPSSTGM-LVCIYFIILFICGNCILVNVFLAI 345
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010500.1 (pep scaffold:Pmarinus_7.0:GL477503:21958:35427:1 gene:ENSPMAG00000009511.1 transcript:ENSPMAT00000010500.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 283.108 bits (723), Expect = 1.479e-86 Identity = 153/308 (49.68%), Postives = 186/308 (60.39%), Query Frame = 1
Query: 4762 SFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVD--QLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVG 5679
S QALPYV LLI MLFFIYA++GMQ+FG + ++E + E +NNFQTF QA+++LFRSATGEAWQ IML CL C+ S N V CGS+FAY YF+SF +CSFL++NLFVAVIMDNF+YLTRD SILGPHHLDEFVR+W +YDP A GRI + + LLR ++PPLG GK CP R A LVRM+MP+ D TV F TL AL+RT L IK + D + + ELR + IW SQK LD +VPP D+TVG
Sbjct: 1 SLQALPYVCLLIAMLFFIYAIVGMQVFGNVKLDDEGGITE---HNNFQTFFQALMLLFRSATGEAWQEIMLSCLSKKPCEQHS----------------------LNGENV------------------------CGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFVRIWGDYDPAATGRITYTKMYELLRHMSPPLGLGKKCPVRIAYKRLVRMDMPIAEDNTVHFTTTLMALIRTALDIKIAKAGADKFECDSELRKEMMAIWPTLSQKTLDILVPPHRAVDLTVG 259
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007700.1 (pep scaffold:Pmarinus_7.0:GL478030:35286:55231:1 gene:ENSPMAG00000006953.1 transcript:ENSPMAT00000007700.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 277.33 bits (708), Expect = 1.515e-81 Identity = 162/241 (67.22%), Postives = 192/241 (79.67%), Query Frame = 1
Query: 2284 VKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
VKS FYWVVI+LVFLNT + SEHY Q WL Q+ AN + + +FT+EML KMYSLG++ YF +FNRFD FVV I+E ++++ M PLG+SVLRC RLLR+FKVT+YW++L NLV SLL SM+SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F QSLLTVFQILTGEDWN VMYDGI +YG + ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S
Sbjct: 15 VKSTGFYWVVIILVFLNTLTIASEHYNQPDWLTQVQDIANKVLLAMFTVEMLTKMYSLGLQAYFVSLFNRFDCFVVFGGIIETILVEFGVMSPLGISVLRCVRLLRIFKVTKYWAALSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQSLLTVFQILTGEDWNAVMYDGIMAYGGPSSTGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAES 255 HSP 2 Score: 154.836 bits (390), Expect = 1.358e-39 Identity = 94/157 (59.87%), Postives = 116/157 (73.89%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLK 3765
RR+S++ KEK+ PIP S+FFIF N R CH + +H F N++L IM+SS LAAEDP+ S RN IL YFDY FT++FTVEI LK+ +YG H G+FCR+ N+LDLLVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK
Sbjct: 305 RRLSDLNLKEKVVPIPEGSAFFIFSSTNPVRVCCHRLIHHHIFTNLILAMIMLSSVSLAAEDPIRNHSFRNNILGYFDYAFTAIFTVEILLKMTSYGAFLHKGSFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLK 461 HSP 3 Score: 88.1965 bits (217), Expect = 1.000e-17 Identity = 59/210 (28.10%), Postives = 107/210 (50.95%), Query Frame = 1
Query: 4342 RYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
R + + S F +++ +L+ LNT+++A + QP QV D N V +FTVE L K+ + G + YF +N FD +V G I+ I + + I+ R R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + K + F FPQ++L +F+ TGE W +M
Sbjct: 8 RRKTRLTVKSTGFYWVVIILVFLNTLTIASEHYNQPDWLTQVQDIANKVLLAMFTVEMLTKMYSLGLQAYFVSLFNRFDCFVVFGGIIETILVEFGVMSP-------LGISVLRCVRLLRIFKVTKYWAALSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKR----STFDNFPQSLLTVFQILTGEDWNAVM 206 HSP 4 Score: 82.4185 bits (202), Expect = 5.556e-16 Identity = 54/149 (36.24%), Postives = 79/149 (53.02%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQV 1443
P P+ A F + NP R C +++ F LIL I + +LAA P R+ + N+ L + F IFT E +LK+ ++G +H G++ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+V
Sbjct: 318 PIPEGSAFFIFSSTNPVRVCCHRLIHHHIFTNLILAMIMLSSVSLAAEDPI--RNHSFRNNILGYFDYAFTAIFTVEILLKMTSYGAFLHKGSFCRNYFNLLDLLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKV 462 HSP 5 Score: 54.299 bits (129), Expect = 3.238e-7 Identity = 70/297 (23.57%), Postives = 129/297 (43.43%), Query Frame = 1
Query: 1051 KFCIK----IVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIM------YWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGV 1908
+FC + V+ F ++++ +F N +A+ Y + D + + V + +FT E + K+ + G AY + +N D +V G+I T+L + P + LR R+LR ++ +L ++ S++ +M + + LL III++++G++LF GK + ++ +T R ++FDNF ++LTVFQ +T E W +M Y S GM IYF+ L I G++ ++N+ L +
Sbjct: 5 RFCRRKTRLTVKSTGFYWVVIILVFLNTLTIASEH-YNQPD--WLTQVQDIANKVLLAMFTVEMLTKMYSLGL----QAYFVSLFNRFDCFVVFGGIIETILVEFGVMSPLGISVLRCVRLLRIFKVTKYWAALSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF----------------------------------------DETQTKR--------STFDNFPQSLLTVFQILTGEDWNAVMYDGIMAYGGPSSTGM-LVCIYFIILFICGNYILLNVFLAI 245
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008632.1 (pep scaffold:Pmarinus_7.0:GL481395:151307:166184:-1 gene:ENSPMAG00000007818.1 transcript:ENSPMAT00000008632.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 274.633 bits (701), Expect = 6.382e-80 Identity = 165/242 (68.18%), Postives = 194/242 (80.17%), Query Frame = 1
Query: 2284 VKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVF-QILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGS 3006
VKS AFYW+VIVLVFLNT + SEHY Q WL Q+TAN + + LFTLEML+K+YSLG++ YF +FNRFD FVV I+E ++++ M PLG+SVLRC RLLR+FK TRYW+SL NLV SLL SM+SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS+FD+F +LLTVF QILTGEDWN VMYDGIR+YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S
Sbjct: 57 VKSTAFYWMVIVLVFLNTLTIASEHYDQMQWLTHVQDTANKVLLALFTLEMLVKIYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELKVMSPLGISVLRCVRLLRIFKATRYWNSLSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQVRRSSFDNFPTALLTVFQQILTGEDWNSVMYDGIRAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAES 298 HSP 2 Score: 160.229 bits (404), Expect = 5.477e-41 Identity = 98/158 (62.03%), Postives = 119/158 (75.32%), Query Frame = 1
Query: 3295 RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPIN-NDAISXXXXXXXXXXXXXXXAINRAKGLK 3765
RR+SE+ KEK+ P+P +S+FF+F N FR CH I NH F N++LV IM+SS LAAEDP+ + S RN IL YFDY FT++FT+EI LK+ YG H G+FCRS N+LDLLVV S+IS+ I + AISVVKILRVLRVLRPLRAINRAKGLK
Sbjct: 387 RRLSELQIKEKVVPMPESSAFFLFSHTNPFRILCHHIINHTIFTNLILVFIMLSSVSLAAEDPIRSTSFRNEILGYFDYAFTTIFTIEIMLKMTAYGAFVHKGSFCRSYFNLLDLLVVGVSLISFGIQWSSAISVVKILRVLRVLRPLRAINRAKGLK 544 HSP 3 Score: 84.3445 bits (207), Expect = 1.973e-16 Identity = 60/169 (35.50%), Postives = 86/169 (50.89%), Query Frame = 1
Query: 946 QIASGGRKRTPARSQSGN---PRPQR-ALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQ 1440
++ G R R + Q P P+ A F + NPFR C I+ F LIL I + +LAA P R ++ N L + F IFT E +LK+ A+G +H G++ R+ +NLLD L+V + LIS + + S VK LR RVLRPLR ++ L+
Sbjct: 379 EVPMGPRPRRLSELQIKEKVVPMPESSAFFLFSHTNPFRILCHHIINHTIFTNLILVFIMLSSVSLAAEDPI--RSTSFRNEILGYFDYAFTTIFTIEIMLKMTAYGAFVHKGSFCRSYFNLLDLLVVGVSLISFGI-QWSSAISVVKILRVLRVLRPLRAINRAKGLK 544 HSP 4 Score: 81.2629 bits (199), Expect = 1.595e-15 Identity = 56/204 (27.45%), Postives = 107/204 (52.45%), Query Frame = 1
Query: 4363 ITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSA-TGEAWQNIM 4971
+ S F +++ VL+ LNT+++A + Q Q V D N V +FT+E L+K+ + G + YF +N FD +V G ++ I + + + I+ R R++R+ K + L+ + + S +++ + LL+ + I++++GMQ+FG +E ++ R ++F FP A+L +F+ TGE W ++M
Sbjct: 57 VKSTAFYWMVIVLVFLNTLTIASEHYDQMQWLTHVQDTANKVLLALFTLEMLVKIYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELKVMSP-------LGISVLRCVRLLRIFKATRYWNSLSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQV----RRSSFDNFPTALLTVFQQILTGEDWNSVM 249 HSP 5 Score: 58.9214 bits (141), Expect = 1.374e-8 Identity = 74/291 (25.43%), Postives = 126/291 (43.30%), Query Frame = 1
Query: 1057 CIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCI-TMEGWTQIMY-WINDSVGMSWP----WIYFVSLIIIGSFFVMNLVLGV 1908
C V+ F ++++ +F N +A+ + + K V + +FT E ++KI + G AY + +N D +V G++ T+L ++ P + LR R+LR + SL ++ S++ +M + + LL III++++G++LF GK N +ET + +SFDNF A+LTVFQ I T E W +MY I G S+P IYF+ L I G++ ++N+ L +
Sbjct: 53 CRAAVKSTAFYWMVIVLVFLNTLTIASEHYDQMQWLTHVQDTANK---VLLALFTLEMLVKIYSLGL----QAYFVSLFNRFDCFVVCGGIVETILVELKVMSPLGISVLRCVRLLRIFKATRYWNSLSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKF------------------------------------------NFDET------QVRRSSFDNFPTALLTVFQQILTGEDWNSVMYDGIRAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAI 288 HSP 6 Score: 51.2174 bits (121), Expect = 3.435e-6 Identity = 43/184 (23.37%), Postives = 83/184 (45.11%), Query Frame = 1
Query: 4231 EGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQS----------FRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYE-QVMDYLNMVFTGVFTVEFLLKLAAFG---FKNYFSDAW-NVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIR 4737
+ +E + R+ E +K K V +P+ S FR +I F +I V IML+++SLA + + + +++ Y + FT +FT+E +LK+ A+G K F ++ N+ D ++V S I + + R+ RV+R ++ ++R +G++
Sbjct: 372 DDDESEPEVPMGPRPRRLSELQIKEKVVP--MPESSAFFLFSHTNPFRILCHHIINHTIFTNLILVFIMLSSVSLAAEDPIRSTSFRNEILGYFDYAFTTIFTIEIMLKMTAYGAFVHKGSFCRSYFNLLDLLVVGVSLISF---------GIQWSSAISVVKILRVLRVLRPLRAINRAKGLK 544
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Yeast
Match: CCH1 (Voltage-gated high-affinity calcium channel; involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and partially co-localizes with Mid1p; however, evidence suggests CCH1 is not required for Mid1p function [Source:SGD;Acc:S000003449]) HSP 1 Score: 105.531 bits (262), Expect = 1.016e-22 Identity = 161/764 (21.07%), Postives = 305/764 (39.92%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFIC----------------------NHPHFGNI---VLVCIMVSSAML-----AAEDPLDAESSRNRILNY---FDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLT---SIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPK-------QSFRYRVWWLITSRPFEYIIFVLIMLNT-ISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFI-DIIYDHVNGTN---NNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGS-NFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDW---SILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSD 5487
S++ F P ++FR+FC + +F +I V V I + +L PL + N+ D F F++E +K + G ++ A+ R+ N +D V+++ ++I+Y NN +S + I+ + + + I L++ L F F V G+ +F G+ +CND S C +Y + + ++ R + L+ D+ +A +L+ + + EGW +L ++S ++F + + + F++N+FV F++ + Y E +K + + +AKP + IP + F Y++ + + F Y F+ ++L I + L P M T VF ++ L + G + YF WN I++ +FI + + HV ++ +N +G L+ I F ++ + + + LL T + S + + +LF +YA+ Q+FG + N NF+T ++++VLFR + GE W IM +LTV + + S Y D CGS +AY +S+ +I ++ +N+FV++I+ NF Y+ R S + + +++ WS++D + G ++ + ++ + PL F K R +LV M +N D
Sbjct: 1155 SYYFFSPQHRFRRFCQRLVPPSTGKRTDGSRFFEDSTDLYNKRSYFHHIERDVFVFIFALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCAFIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLISMWINLIAYLKNNGNLSRIFKGLTALRALRCLTISNT-ARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGSLG-RADCYNEY---SNSVFQWDIMSPRVYQQPYLHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSAGNALFLVLFNFLSMVFILNLFVSFIVNNQARTTGSAYFTIE-EKAWLESQKLLSQAKP--KAIPNLIELSRVRQFFYQL--AVEKKNFYYASFLQVVLYLHIIMLLSRSYNPGNLIGYQGVYFMFSTSVFLIQEALHMCGEGPRLYFRQKWNSIRLSIIIIAFIMNAVAFHVPASHYWFHNIKGFFLLVIFLF----------IIPQNDTLTELLETAMASLPPILSLTYTWGVLFLVYAIALNQIFGLT-----RLGSNTTDNINFRTVIKSMIVLFRCSFGEGWNYIMA--------------------DLTVSEPYCSSDDN----------------------STYTD---CGSETYAYLLLMSWNIISMYIFVNMFVSLIIGNFSYVYRSGGSRSGINRSEIKKYIEAWSKFDTDGTGELELSYLPRIMHSFDGPLSF-KIWEGRLTIKSLVENYMEVNPD 1847 HSP 2 Score: 74.7146 bits (182), Expect = 2.570e-13 Identity = 55/218 (25.23%), Postives = 108/218 (49.54%), Query Frame = 1
Query: 1192 IELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIM-RAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWP 1842
++ FI F+ E ++K +A GFI P AYLRN WN +DF V+I + +++ + G + + LR LR ++ + + N +M + +F L++L ++ + + GL +F G+L TC ND S+ + +++ +S F++ + + P + + D+F A +++Q I++EGW ++ + +S G+ P
Sbjct: 1245 LDCAFIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDF-CVLISMWINLIAYLKNNGNLSRIFKGLTALRALRCLTISNTARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRL-GTC---ND----------GSLGRADCYNEYSNSVFQWDIMSPR----VYQQPYLHL---DSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTP 1440 HSP 3 Score: 70.0922 bits (170), Expect = 6.689e-12 Identity = 65/280 (23.21%), Postives = 122/280 (43.57%), Query Frame = 1
Query: 1267 PGAYLRNGWNLLDFLIVI---IGLISTVLSKMSEGGPDV-KALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPV---------------PCST-------------SVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGY 2010
P A+ R+ WN +D + + +G+ ++ S ++ G + K L R+LR + + +G+PS ++ + + L +++ + ++ I + I+G+++F G C N E P P + SV+KG+ C + C N N P G SFDN +M VF ++ +T +MY+ DS M+ ++F+ I + + +++NL++ VL F E+ KK+ +R+ V GY
Sbjct: 486 PRAFARSSWNRIDLVSSVSFWLGMFLSIKSYDTKTGIRIFKPLAILRILRLVNVDTGMPS---ILRGLKYGIPQLVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNP---EDPTDTYQYDMQFCGGYLDPVTKRKQNYIYEDGSEGSVSKGFLCPQYSK------CVSNAN-------PYNGRISFDNIVNSMELVFVIMSANTFTDLMYYTMDSDEMA-ACLFFIVCIFVLTIWLLNLLIAVLVSSFEIANEEYKKKKFIYGSRKTGYVARIVTGY 745
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO46991 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNU9]) HSP 1 Score: 1522.29 bits (3940), Expect = 0.000e+0 Identity = 920/1787 (51.48%), Postives = 1173/1787 (65.64%), Query Frame = 1
Query: 937 LSAQIASGGRKRTPARSQ--SGNPRPQRALFCLTLRNPFRKFCIKI-------VEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSK--NDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKS-SMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMN------GDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDA--ISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHC--LPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIK--TDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVV-PPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRT-HGRGSGPLISLISPTL--VTTNECDEKDKD-YLPSHLGAERRTHSIFGTMMNVL------QRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNE---EYSAEIPPKLP 6183
L+ Q G P R + + RP+RALFCLTL NP R I + V PF+ +IL TIFANC ALAA P PE+DS+ IN LE E VF+ IFT E VLKI+A+GF+MHPGAYLRNGWN+LDF+IV++GL + ++ + DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++A++PLFHIALL +FV+IIYAIIG+ELF GKLHSTCY + P PCST ++GY C + +G +C +W GPN GIT+FDN GLA LTVFQCIT+EGWT +MY IND++G SWPW+YFV+LII GSFFV+NLVLGVLSGEF+KE+ +A+K G++QK RE+ D+ GYLDWI AEDI D E GK R K S + +D +S + + + A Q ++ K + ++++ R RR CR+ VK+Q FYW VIV VFLN+ L EHY Q +L F + AN +F+ LFTLEM++KMY LG YF +FNRFD VVI S+LE+ + + P+G+S+LRC RLLR+FKVTRYWSSL NLV SLL SM+SI+ LL+LL LF+VIFSLLGMQ+FGGKFN + PRSNFDSF ++L+TVFQILTGEDWN VMY GI+S+G + +S S + LY++ L + GNYILLNVFLAIAVDNLAD S + E+++ + E E E K +S+ N T + RLIK + N G I +RK T+ E+ + + ++ +EVM E P+P SS FIF N FR CH I + +F N +L+ I+VSS MLAAEDPL++ S RN++LNYFDY FT+VFT+EIT+K+I YG++ H G+FCRS+ N+LD LVV SI+S + + + ISVV+ILRVLRVLRPLRAINRAKGLK VVQCV VAVK+IGNIMLVT L F+FAVIGVQLF G F SC D K T C+GQYI + + V REW NF++VP AMLTLF V TFEGWPG+L S+DS D NNRP V+I+Y+ YII+IAFFMINIFVGFVIVTFQ EGEEE+K+CELDKNQRKC+EFALKA+P RRYIP ++ VW ++TS+PFEY+IF I NTI L +++ +P+ Y +V+D N+ FT VF +E +LKL AF KNYF D WN+FDF++V+GS +DI T N +++ + FFRLFR +RLVKLL++G GI+TLLWTF+KSFQALPYV LLI+M FFIYAV+GMQMFG+I + E +INRNNNFQTFPQ+++VLFRSATGE WQ IML C P+A CD N Y + CG++FAY YF SFY ICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVR+WSEYDPEA G +KH+D+VT+L++I PPLGFGK+CPHR AC LV MNMPLN DGTV FNATLF LVRT+L IK ++++ NEE+R +I K+W +TSQ+ LD+++ PP G+D+VTVGKFYAT+LIQE+FRR+K ++ E + S + RT HG G P L + D+ D++ +L + + + + ++ N + R S RR + S ++ R +S P L S P +L L P + V +N+ + SA +P K P
Sbjct: 18 LNGQPKYGKPPPQPKRQKKPTNAVRPKRALFCLTLGNPIRSTAISLFTVFFLDVFRTPFDVMILITIFANCAALAAFQPLPEQDSSLINEELEVAEFVFLGIFTMESVLKIIAYGFVMHPGAYLRNGWNILDFVIVVVGLATIIVKLYTPDSFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKALIPLFHIALLVVFVVIIYAIIGVELFMGKLHSTCYDNVTGQPTFDEPHPCSTE-SEGYSCSN---AGPGQVC------LKKWEGPNYGITNFDNIGLACLTVFQCITLEGWTDVMYSINDAIGNSWPWLYFVTLIIWGSFFVLNLVLGVLSGEFAKEKARAQKSGEFQKLREKQLVDDAYHGYLDWISQAEDIEGDSSAGEDEEGKADR-------KPSFRRRKENDDISKNKENQEDSAA---SDQGWI---DRKKKILKRFHHRLRRSCRKAVKTQWFYWTVIVFVFLNSLTLALEHYNQPEFLTQFLDKANKLFLALFTLEMVVKMYCLGFHGYFASLFNRFDCLVVISSLLELGLTEAMDQRPIGISMLRCVRLLRIFKVTRYWSSLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGKFNLGDEDVPRSNFDSFWRALVTVFQILTGEDWNAVMYTGIQSWGGITESLSAIPILYFIFLVVVGNYILLNVFLAIAVDNLADAESLTEMEEEKKKEREEELEMKLRMEEKESSSNKDLENKRASTSSGKSHRLIKIWKTNELLHLAGKIRVSRLRKHPI---TDAESPSLAEDSKATLNRDHESVRSATSTEVMDHE---PMPPESSLFIFSNTNCFRVVCHRIATNSYFVNFILLLIIVSSCMLAAEDPLNSNSKRNQVLNYFDYFFTAVFTIEITIKIIAYGVILHKGSFCRSAFNLLDFLVVAVSIVSIALRDSSSQISVVRILRVLRVLRPLRAINRAKGLKHVVQCVFVAVKTIGNIMLVTVLFNFLFAVIGVQLFKGTFFSCTDAEKITKRECQGQYIEFKGPGLTNPVVKDREWQPQTFNFNDVPQAMLTLFTVMTFEGWPGILESSMDSTDVDEGPFLNNRPWVAIYYVIYIIIIAFFMINIFVGFVIVTFQNEGEEEFKDCELDKNQRKCVEFALKARPTRRYIPTNRLQFHVWRVVTSQPFEYLIFAFITGNTILLMMQYYNEPKLYTRVLDGFNIGFTSVFLLECILKLFAFKPKNYFLDRWNLFDFVVVVGSVVDI-------TMNEVSSEQMFAFGFFRLFRALRLVKLLNQGSGIKTLLWTFIKSFQALPYVGLLIIMTFFIYAVVGMQMFGRIAIDPE---TQINRNNNFQTFPQSLMVLFRSATGENWQLIMLACTDTPNAKCDP------------------------------------------NAYPQDTDGL--CGTDFAYAYFCSFYAICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRVWSEYDPEASGCVKHVDIVTVLKRIAPPLGFGKFCPHREACKRLVSMNMPLNRDGTVNFNATLFGLVRTSLSIKRPEGKGSLEKANEEMRAIIMKVWPKTSQEFLDEIIQPPGGDDEVTVGKFYATYLIQEYFRRFKARQRAENAQYQDAHSTQALQAGLRTLHGLG---------PQLRRAISGHLDDDDEELFLKEDIQQKSQHKRFWESLKNAVTPSPRHSRPSSLRRPGSIRLSAFIKKGNSTPEAQRKSSLPATLTFSHGPLLTSDRQL-LVPPQQSDVNANDKESKQSAHVPSKPP 1711
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO36844 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHI0]) HSP 1 Score: 226.868 bits (577), Expect = 3.485e-59 Identity = 180/573 (31.41%), Postives = 296/573 (51.66%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDP-LDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTS----IISYPIN--NDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCND--VSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQ--------EGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDH------VNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEK-EMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMC 4998
S ++F P+N+FR + + F VL+ I+++ ++A E P + S R+++ Y+F +FT+E+ +KVI GL A+ RS N++D +V+ S I++ N N + V+++ R LR LRPLR I+RA GLK VV+ ++ ++K IGNI+L+ +F ++GVQLF GKF C D V T C N W+N NFDN+ A+LTLF ST +GW ++Y ID+ D I N+ I+++ ++++ F ++N+ VG V+ FQ+ + +E K + ++ R+ E A Y + F + V T F+ I +I LN + +AL+ +QP + N VFT VF +E +LK+ A G K Y D WN D +IV+ S + I + +N T I R+ R+ R++KLL EGIR LL T ++ + + +L +++FFI++ +G+++FGKI E + ++ + NF++F A+L LFR +TG+ W I+ + +C
Sbjct: 910 SLYVFAPDNRFRMLNKELYQNKWFDRTVLLFILLNCVVMALEGPSVLPGSLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFHYCTDATVPVTTKTEC---------------LENGGSWVNREYNFDNLAKALLTLFVFSTKDGWVNIMYDGIDAVGIDKQPIRNHARYNVIYFVGFLLLAGFVVLNMLVGVVVENFQKCRTLIEMEKKIDEEKKNKKEEKMRR--EIAEDEALSEHYPRPRKFIHAV---CTHGYFDLGIAAVIALNVLCMALEHYQQPDGLTAFLKCANYVFTAVFILEAILKIFALGIKRYIKDRWNQLDMLIVILSIVGIALEEMTMELPINPT----------IIRVMRVLRIARVLKLLKTAEGIRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELFGKIDCEKPGITCQGMDEHANFRSFGIAMLTLFRISTGDNWNGILKDTISPDVC 1452 HSP 2 Score: 144.05 bits (362), Expect = 6.034e-34 Identity = 102/352 (28.98%), Postives = 171/352 (48.58%), Query Frame = 1
Query: 973 TPARSQSGNP-------------RPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEK--IEL---VFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDV----KALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMS---------WPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKER 1935
TP S + NP R +L+ N FR ++ + K F+ +L I NC +A P + + +LE+ I++ VF+ IFT E ++K++A G + P AYLR+GWN++D +V+I + +++ + G + + RA R LRPLR++S P L++V+ +++ ++ P+ +I L+A II+ I+G++LF GK H ++ VP +T K C +N W +FDN A+LT+F T +GW IMY D+VG+ + IYFV +++ F V+N+++GV+ F K R
Sbjct: 883 TPCMSPTDNPTVDIKVPTSCCSKRADWSLYVFAPDNRFRMLNKELYQNKWFDRTVLLFILLNCVVMALEGP------SVLPGSLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFH--------YCTDATVPVTT----------------KTECLENGGS---WVNREY---NFDNLAKALLTLFVFSTKDGWVNIMYDGIDAVGIDKQPIRNHARYNVIYFVGFLLLAGFVVLNMLVGVVVENFQKCR 1198 HSP 3 Score: 128.257 bits (321), Expect = 3.973e-29 Identity = 92/241 (38.17%), Postives = 141/241 (58.51%), Query Frame = 1
Query: 2284 VKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKA----KPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLA 2994
V S+ F +V++ +F+NT + E+Y Q + N IF +F +EM++K+ LG Y FN FD +VI S++E+ G+SVLR RLLRVFK+ R+ +LR + ++ +M ++++ L LL +F+ S+LGM LFGGK+ F R+NFD +++TVFQ+LT EDWN VMYDG+R+ +S + LY+++L GNYIL N+ +AI V+ A
Sbjct: 408 VDSKWFMYVIMGAIFVNTLTMGIEYYGQPQKMTDVLEIFNYIFTAIFGIEMIMKLIGLGFYGYIKDAFNIFDGTIVIISVVELFGDDDS-----GISVLRSFRLLRVFKLVRFLPALRRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGKYRFPNDEGVMETSRANFDDLFWAIVTVFQVLTQEDWNIVMYDGMRA------TSKWAGLYFILLMTIGNYILFNLLVAILVEGFA 637 HSP 4 Score: 105.916 bits (263), Expect = 2.137e-22 Identity = 75/249 (30.12%), Postives = 126/249 (50.60%), Query Frame = 1
Query: 1372 VKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSK---------------------NDVMMESP------------VPCSTSVNKGYQCDDFHSSGFKYMCKDNK----NETSRWSG-----PNMGI------TSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF--SKEREKAKKRGKYQK 1968
+ A+RA RVLRPLR ++ +PS+++++ ++ + L ++ + + I+ I+G++++ G L S C ++ +D++ P +P ST+ G +C G Y N+ N + W+ +MGI SFDN +A + +FQ IT+EGWT IMY+I D+ G W +IYFV LI+IGS+F+ NL L V++ +F +K+RE R +K
Sbjct: 1 MTAVRAIRVLRPLRAINRVPSIRILVTLLLDTLPMLGNVLAMCSLIFSIFGIVGVQMWQGVLRSRCVAQLPGNLSANQLNISAFYQPGGSSDLVCSLPENSGDKHCTSAFIPASTA--HGREC------GLTYEQYSNRSNYTNVCANWNQYYTLCADMGINPLYDAVSFDNILIAWVAIFQVITLEGWTDIMYYIQDAHGF-WNFIYFVVLIVIGSYFMTNLCLVVITTQFQETKQRENDLMRQSRRK 240 HSP 5 Score: 103.605 bits (257), Expect = 1.111e-21 Identity = 60/204 (29.41%), Postives = 108/204 (52.94%), Query Frame = 1
Query: 4363 ITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-GKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
+ S+ F Y+I I +NT+++ +++ QPQ+ V++ N +FT +F +E ++KL GF Y DA+N+FD IV+ S +++ D +G I+ R FR++R+ KL+ +R L + + + L+V+ F +++GM +F GK N++ + E +R NF AI+ +F+ T E W +M
Sbjct: 408 VDSKWFMYVIMGAIFVNTLTMGIEYYGQPQKMTDVLEIFNYIFTAIFGIEMIMKLIGLGFYGYIKDAFNIFDGTIVIISVVELFGDDDSG------------ISVLRSFRLLRVFKLVRFLPALRRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGKYRFPNDEGVMETSR-ANFDDLFWAIVTVFQVLTQEDWNIVM 598 HSP 6 Score: 94.7449 bits (234), Expect = 5.024e-19 Identity = 82/316 (25.95%), Postives = 139/316 (43.99%), Query Frame = 1
Query: 1045 FRKFCIKIVEWKPFEYLILFTIFANCCALAANT-PYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFH-----IALLALFVIIIY--AIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMS--WPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKY 1962
FR C V+ K F Y+I+ IF N + P++ + LE +F IF E ++K++ GF Y+++ +N+ D IVII +V+ + + LR+FR+LR +LV LP+L+ R ++ + H + LAL VI ++ +I+G+ LF GK +++ + ETSR +FD+ A++TVFQ +T E W +MY D + + W +YF+ L+ IG++ + NL++ +L F+ G Y
Sbjct: 400 FRDGCASSVDSKWFMYVIMGAIFVNTLTMGIEYYGQPQK----MTDVLEIFNYIFTAIFGIEMIMKLIGLGFY----GYIKDAFNIFDGTIVII----SVVELFGDDDSGISVLRSFRLLRVFKLVRFLPALR-------RQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGK------------------------------------YRFPNDEGVMETSR--------ANFDDLFWAIVTVFQVLTQEDWNIVMY---DGMRATSKWAGLYFILLMTIGNYILFNLLVAILVEGFASAPAGYDSEGNY 649 HSP 7 Score: 76.6406 bits (187), Expect = 1.652e-13 Identity = 63/196 (32.14%), Postives = 112/196 (57.14%), Query Frame = 1
Query: 2311 VIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQ-TDAMP--PLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKA------KPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGI 2871
+ ++ LN + EHY+Q L +F AN +F +F LE ++K+++LG++ Y +N+ D +VI SI+ I + + T +P P + V+R R+ RV K+ + +R L+ ++ ++ + +L +L L IFS LG++LFG K + +K +NF SF ++LT+F+I TG++WN ++ D I
Sbjct: 1253 IAAVIALNVLCMALEHYQQPDGLTAFLKCANYVFTAVFILEAILKIFALGIKRYIKDRWNQLDMLIVILSIVGIALEEMTMELPINPTIIRVMRVLRIARVLKLLKTAEGIRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELFG-KIDCEKPGITCQGMDEHANFRSFGIAMLTLFRISTGDNWNGILKDTI 1447 HSP 8 Score: 70.8626 bits (172), Expect = 1.123e-11 Identity = 64/259 (24.71%), Postives = 114/259 (44.02%), Query Frame = 1
Query: 1048 RKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP----DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCD--DFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIM 1806
RKF + F+ I I N +A Y + D + + L+ VF +F E +LKI A G Y+++ WN LD LIVI+ ++ L +M+ P ++ +R R+ R L+L+ ++ +++++ +A+ + ++ +L L + I++ +G+ELF GK+ E P G C D H+ +F +FG+AMLT+F+ T + W I+
Sbjct: 1237 RKFIHAVCTHGYFDLGIAAVIALNVLCMALEH-YQQPDG--LTAFLKCANYVFTAVFILEAILKIFALGI----KRYIKDRWNQLDMLIVILSIVGIALEEMTMELPINPTIIRVMRVLRIARVLKLLKTAEGIRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELF-GKIDC----------EKP---------GITCQGMDEHA-------------------------NFRSFGIAMLTLFRISTGDNWNGIL 1443 HSP 9 Score: 66.2402 bits (160), Expect = 2.238e-10 Identity = 73/269 (27.14%), Postives = 138/269 (51.30%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQ----NTANIIFVVLFTLEMLIKMYSLGM----RCYXXXXXXXXXXXXXXXSILEIVMIQT--DAMPPLGV-SVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAK-PRS-----------------NFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYG----NLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDN 2988
L +++ F V++ + LN V+ E S+ S + + +F+ +FT+EM++K+ +LG+ Y +N D F+V+ S +++++ T LGV V R R LR +V L+ +V +L++S+K I +++++ F +IF +LG+QLF GKF++ A P + NFD+ ++LLT+F T + W +MYDGI + G + + + +Y+V + +++LN+ + + V+N
Sbjct: 927 LYQNKWFDRTVLLFILLNCVVMALEG--PSVLPGSLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFHYCTDATVPVTTKTECLENGGSWVNREYNFDNLAKALLTLFVFSTKDGWVNIMYDGIDAVGIDKQPIRNHARYNVIYFVGFLLLAGFVVLNMLVGVVVEN 1193
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO35497 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLD1]) HSP 1 Score: 213.772 bits (543), Expect = 6.964e-59 Identity = 169/538 (31.41%), Postives = 294/538 (54.65%), Query Frame = 1
Query: 3379 KFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNR-ILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTS----IISYP--INNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
+FR+ +C+H F ++LV I+ S A+LA E P AE R I++ +FT +FT+E+ +K++ GLV G + R ++LD +V+ S I++Y ++ + + +++ R LR LRPLR I RA GLK VVQ ++ ++K IGN +L+ + MF ++GVQLF GKF C ++H+ + + +W+N NFD++ A+++LF VST +GW +++ ID+ D I N +++I ++++ F ++N+ VG V+ FQ+ E E + RK + + + Y R ++ ++ T R ++ I +I +N I ++L+ K PQ + + +Y FT VF +E ++K+ A GF Y D WN+ D IVL S I+ + + ++ + ++ R+ RV++LVKL +G+R+LL T ++ +P + LL +LFFIY+ +G+Q+FG + ++ + NR+ +F+ F A+L LFR ATG+ W I+
Sbjct: 7 RFRQRMRAVCSHRAFDYVILVFIIFSCAVLAIEAPDIAEQGLKRQIIDISMLVFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSHVSPEVLGTLRVFRALRTLRPLRVIRRAPGLKLVVQTLLYSLKPIGNTVLIAAIFFVMFGILGVQLFKGKFYYCEG---DSHVISKQECANSTRG----------QWVNRRYNFDDLLQALISLFVVSTKDGWVEIMHHGIDAVDVDVQPIVNYAEWRLVYFIPFLLLGGFLVLNMIVGVVVENFQR-CRERMDEEEQARPHRKGKKARNQMQDSLYYESYGPLRLKIHFICTHRNWDITIAAIICINVICMSLEHYKMPQVFVETTNYF---FTSVFVIEVVVKVIALGFVRYPKDRWNLIDLAIVLLSVTGIVLELLVKVDHLFNPTVIRTLRVLRITRVLKLVKL---AKGVRSLLDTLFEALPQVPNLGLLFFLLFFIYSCLGIQLFGSLECSHDYPCQGFNRHAHFRDFGTAMLTLFRIATGDNWNGIL 524 HSP 2 Score: 139.428 bits (350), Expect = 5.567e-34 Identity = 94/338 (27.81%), Postives = 170/338 (50.30%), Query Frame = 1
Query: 1045 FRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDV----KALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTS-----VNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGM---------SWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSK------EREKAKKRGKYQKAREQMQ 1986
FR+ + + F+Y+IL I +C LA P + ++ LVF +IFT E ++K++A G ++ PG YLR+GW++LD +V++ I +++ S P+V + RA R LRPLR++ P L++V+ +++ ++ P+ + L+A +++ I+G++LF GK + Y + D + S C+ S VN+ Y +FD+ A++++F T +GW +IM+ D+V + W +YF+ +++G F V+N+++GV+ F + E E+A+ K +KAR QMQ
Sbjct: 8 FRQRMRAVCSHRAFDYVILVFIIFSCAVLAIEAP-DIAEQGLKRQIIDISMLVFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSHVSPEVLGTLRVFRALRTLRPLRVIRRAPGLKLVVQTLLYSLKPIGNTVLIAAIFFVMFGILGVQLFKGKFY---YCEGDSHVISKQECANSTRGQWVNRRY--------------------------------NFDDLLQALISLFVVSTKDGWVEIMHHGIDAVDVDVQPIVNYAEWRLVYFIPFLLLGGFLVLNMIVGVVVENFQRCRERMDEEEQARPHRKGKKARNQMQ 309 HSP 3 Score: 103.99 bits (258), Expect = 2.196e-22 Identity = 64/233 (27.47%), Postives = 116/233 (49.79%), Query Frame = 1
Query: 4339 FRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQR--YEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF--------------GKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLH 4977
FR R+ + + R F+Y+I V I+ + LA++ ++ Q++D +VFT +FT+E L+KL A G Y D W+V D +V+ S+IDII + + + G ++ FR R +R ++++ R G++ ++ T + S + + L+ + F ++ ++G+Q+F K N + +NR NF QA++ LF +T + W IM H
Sbjct: 8 FRQRMRAVCSHRAFDYVILVFIIFSCAVLAIEAPDIAEQGLKRQIIDISMLVFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSHVSPEVLG----TLRVFRALRTLRPLRVIRRAPGLKLVVQTLLYSLKPIGNTVLIAAIFFVMFGILGVQLFKGKFYYCEGDSHVISKQECANSTRGQWVNRRYNFDDLLQALISLFVVSTKDGWVEIMHH 236 HSP 4 Score: 67.0106 bits (162), Expect = 9.382e-11 Identity = 67/226 (29.65%), Postives = 118/226 (52.21%), Query Frame = 1
Query: 2293 QAFYWVVIVLVFLNTGVLTSEH--------YRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGM----RCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPP--LG-VSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNF------------------DKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGI 2871
+AF +V++V + + VL E RQ I + + ++F ++FT+EMLIK+ ++G+ Y ++ D F+V+ S ++I++ T + P LG + V R R LR +V R L+ +V +LL S+K I + +++ +F V+F +LG+QLF GKF + + R NFD +Q+L+++F + T + W E+M+ GI
Sbjct: 19 RAFDYVILVFIIFSCAVLAIEAPDIAEQGLKRQII------DISMLVFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSHVSPEVLGTLRVFRALRTLRPLRVIRRAPGLKLVVQTLLYSLKPIGNTVLIAAIFFVMFGILGVQLFKGKFYYCEGDSHVISKQECANSTRGQWVNRRYNFDDLLQALISLFVVSTKDGWVEIMHHGI 238
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO46797 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP56]) HSP 1 Score: 220.32 bits (560), Expect = 2.556e-57 Identity = 197/652 (30.21%), Postives = 318/652 (48.77%), Query Frame = 1
Query: 3379 KFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAED-PLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSI-ISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKR--------EWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQ--QEGEEEYKNCE--LDKNQRKCIEFALKAK----PVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPH---NFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLII-NLFVAVIMDNFD 5268
KFR H +F +L +MVSS L ED L + R LN+ ++LF ++F++E LKVI +G V ++ S N LD L+V + ++ N +SV + R +R LRPLRAI+R G+K V+ + A+ IG++++V+ L MF++ GVQLF GKF C + +E V NK W+N +NFDNV N L L V+T+EGW V+ ++DS K D Y I +++ +IIV +FF++N+FVG +I F ++ EE + L ++QRK ++ + A P R P FR +++ L++S FE I +IM N + ++ QP + +Y V G+F +E ++K+ A +YF AW++FDF++V+ S + + + G + R+FRV RL++++ + IR LL + S AL + L+ ++ FIYA+IGM FG I K+ +N NF+TF +I+++FR TG W +I+ D++V+ PPH NF + CG +++ Y++ FLII N+++AV++DN +
Sbjct: 781 KFRCRVRCFVEHRYFEWFILFTVMVSSFTLVFEDIHLHQKPDLERALNFLNFLFAAIFSLEFILKVIGFGFV----SYFTSVWNCLDALIVSVCVSVACLFENPNLSVFRSFRTVRGLRPLRAISRLGGMKVVINALFAAIPGIGSVLVVSMLFWLMFSISGVQLFAGKFYKCVNAE--------------DEKLSPSVIPNKTACLDHPDYRWVNANVNFDNVINGFLALLQVATYEGWMEVMADAVDSTKIDQQPSYEANLIAYAYFVVFIIVGSFFVLNLFVGVIIDNFNTLKKKYEEINSMGMLLTESQRKWVQILMAAAKRKPPSNRLRPTDCFRGKLFDLVSSNQFEVFILTVIMCNMGMMMVQHYDQPPLTTVIGNY---VLVGIFLLEAIIKIIAMRL-HYFKKAWSIFDFVVVVSSIVGMYLGMSTESAVVSPG----LLRVLRVFRVARLLRVVQFAKRIRQLLVAIIISMPALFNIGTLLFLVMFIYAIIGMSSFGNI-----KKQGALNDLVNFETFSSSIILIFRLGTGTGWNDIL-------------------------------------DALVVQPPHCDPNFGGLP----------NGNCGFPIGAVFYLVTYIVSVFLIIVNMYIAVLLDNVN 1354 HSP 2 Score: 146.747 bits (369), Expect = 8.335e-35 Identity = 98/312 (31.41%), Postives = 158/312 (50.64%), Query Frame = 1
Query: 1015 ALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKAL---RAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY--SKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWS-GPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKE 1932
+L CL +P R FCI ++ FE ++ I NC L N P PE + E +F I+T E + KI++ GF+ AYLR+ WN LD L+V + +S PD+ +L R RVLR R +S L L+ ++NS++R++ L + +L LF + + A+IGL+LF+G+L + C + N + +P + C ++G C N + P+ G T+FD+ G +++ FQ +TM+ W + + S+G W +YFV I SF+++NLVL V+ + E
Sbjct: 40 SLLCLGPVHPLRMFCILLITHPYFEIIVTLVILVNCIILGLNDP-PE-----------EAEYIFTAIYTLEMICKIISRGFVKDSYAYLRDTWNWLDSLVVFLSYLSL--------APDIASLSGIRTLRVLRAFRTISALKGLRAMVNSLLRSLKLLTDVLVLFLFSLCVLALIGLQLFTGELRNKCVLETANATTINNPSSWYHREGEPLLCGFSSTAG---RCPANYTCVAHVGPNPDHGFTNFDDIGWSLVMAFQILTMDFWENLYDRVLRSMG-EWYMMYFVVGIFSCSFYLLNLVLAVVYMSYHHE 327 HSP 3 Score: 118.242 bits (295), Expect = 3.501e-26 Identity = 92/323 (28.48%), Postives = 161/323 (49.85%), Query Frame = 1
Query: 1021 FC-LTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRV---LRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSW---------PWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKK 1950
FC L R R F VE + FE+ ILFT+ + L + + + + AL + +F IF+ E +LK++ FGF+ +Y + WN LD LIV + + L + P++ R+FR LRPLR +S L ++VV+N++ A+ + + ++++ ++++I G++LF+GK + ++++ + S +P T+ C D+ + RW N+ +FDN L + Q T EGW ++M DS + + YFV II+GSFFV+NL +GV+ F+ ++K ++
Sbjct: 777 FCWLKFRCRVRCF----VEHRYFEWFILFTVMVSSFTLVFEDIHLHQKPD-LERALNFLNFLFAAIFSLEFILKVIGFGFV----SYFTSVWNCLDALIVSVCVSVACLFE----NPNLSVFRSFRTVRGLRPLRAISRLGGMKVVINALFAAIPGIGSVLVVSMLFWLMFSISGVQLFAGKFYKCVNAEDEKLSPSVIPNKTA------------------CLDHPDY--RWVNANV---NFDNVINGFLALLQVATYEGWMEVMADAVDSTKIDQQPSYEANLIAYAYFVVFIIVGSFFVLNLFVGVIIDNFNTLKKKYEE 1063 HSP 4 Score: 92.8189 bits (229), Expect = 2.001e-18 Identity = 59/205 (28.78%), Postives = 107/205 (52.20%), Query Frame = 1
Query: 4372 RP-FEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCL 4983
RP F+ II LI+LNT+ L + + P V+D LN +FTG+F +E ++K+ AFG Y + WN+FD +I++ S + + GT+ ++ FR+ R++R++ L E + L+ S + + ++ ++ +++AV+GM++FG T + I R NF F + +++FR E W + C+
Sbjct: 479 RPLFDGIIAGLILLNTVVLTMYYHGMPDDLTFVLDILNAIFTGLFILEMIVKIFAFGLVKYICNKWNLFDSVIIITSAV----AYFLGTSTG--------VSIFRILRLLRVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHYTAEAFGSRGIPR-WNFTDFTHSFMMVFRILCSE-WVEPLWDCM 669 HSP 5 Score: 87.4261 bits (215), Expect = 1.004e-16 Identity = 70/245 (28.57%), Postives = 130/245 (53.06%), Query Frame = 1
Query: 2284 VKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMP-----PLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFN---FDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLA 2994
++ F ++ L+ LNT VLT ++ L + N IF LF LEM++K+++ G+ Y +++ + V+I T A+ GVS+ R RLLRV + + W ++ L+ ++ S+ I ++ +L + I +F+++GM++FG + F + PR NF F S + VF+IL E W E ++D +R ++ + L+++ I GN+I+LN+F+A+ +++ A
Sbjct: 477 IQRPLFDGIIAGLILLNTVVLTMYYHGMPDDLTFVLDILNAIFTGLFILEMIVKIFAFGLVKY----------ICNKWNLFDSVIIITSAVAYFLGTSTGVSIFRILRLLRVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHYTAEAFGSRGIPRWNFTDFTHSFMMVFRILCSE-WVEPLWDCMRV------TNTAALLFFLPALIVGNFIVLNLFVALLLNSFA 704 HSP 6 Score: 73.559 bits (179), Expect = 1.553e-12 Identity = 71/276 (25.72%), Postives = 132/276 (47.83%), Query Frame = 1
Query: 3346 ASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQS-CNDVSKNTHISCRGQYIYYNEAD-------------------IAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDY 4113
+S GP + R FC + HP+F IV + I+V+ +L DP + +Y+FT+++T+E+ K+I+ G V + A+ R + N LD LVV S +S + ++S ++ LRVLR R + A+ KGL+ +V ++ ++K + +++++ + A+IG+QLF G+ ++ C + N Y+ E + +A V N NFD++ +++ F + T + W + + + S E Y
Sbjct: 38 TASLLCLGPVHPLRMFCILLITHPYFEIIVTLVILVNCIILGLNDPPEEA----------EYIFTAIYTLEMICKIISRGFVKDSYAYLRDTWNWLDSLVVFLSYLSLAPDIASLSGIRTLRVLRAFRTISAL---KGLRAMVNSLLRSLKLLTDVLVLFLFSLCVLALIGLQLFTGELRNKCVLETANATTINNPSSWYHREGEPLLCGFSSTAGRCPANYTCVAHVGPNPDHGFT---NFDDIGWSLVMAFQILTMDFWENLYDRVLRSMGEWY 297 HSP 7 Score: 71.633 bits (174), Expect = 5.002e-12 Identity = 72/306 (23.53%), Postives = 131/306 (42.81%), Query Frame = 1
Query: 1057 CIKIVEW--KP-FEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQ 1965
C +VE+ +P F+ +I I N L T Y + + L+ + +F +F E ++KI AFG + Y+ N WNL D +I+I ++ L S G V R R+LR L L ++ ++ +I ++ P+F+I + +I ++A++G+ +F Y + F S G RW +F +F + + VF+ + E W + + W V + ++F+ +I+G+F V+NL + +L F+K+ E + Q
Sbjct: 470 CSALVEFIQRPLFDGIIAGLILLNTVVL---TMYYHGMPDDLTFVLDILNAIFTGLFILEMIVKIFAFGLV----KYICNKWNLFDSVIIITSAVAYFLGT-STG---VSIFRILRLLRVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPH--------------------------YTAEAFGSRGIP-----------RW--------NFTDFTHSFMMVFRILCSE-WVEPL-WDCMRVTNTAALLFFLPALIVGNFIVLNLFVALLLNSFAKKEEDLHREASEQ 717 HSP 8 Score: 66.2402 bits (160), Expect = 2.723e-10 Identity = 76/327 (23.24%), Postives = 140/327 (42.81%), Query Frame = 1
Query: 4327 PKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKN----YFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-GKITTENEKEMKEINRNNN----FQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFND---SMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDY 5271
P R LIT FE I+ ++I++N I L L + P+ E + FT ++T+E + K+ + GF Y D WN D ++V S++ + D + S++ R RV+R + +S +G+R ++ + ++S + L V +L + + A+IG+Q+F G++ + E NN + + +L F S G C + C A V G F+D S+V+ F + ++ + + Y V + + YF+ CSF ++NL +AV+ ++ +
Sbjct: 46 PVHPLRMFCILLITHPYFEIIVTLVILVNCIILGL--NDPPEEAEYI-------FTAIYTLEMICKIISRGFVKDSYAYLRDTWNWLDSLVVFLSYLSLAPD-------------IASLSGIRTLRVLRAFRTISALKGLRAMVNSLLRSLKLLTDVLVLFLFSLCVLALIGLQLFTGELRNKCVLETANATTINNPSSWYHREGEPLLCGFSSTAGR--------CPANYTCVA------------HVGPNPDHGFTNFDDIGWSLVM----AFQILTMDFWENLYDRVLRSMGEWYMMYFVVGIFSCSFYLLNLVLAVVYMSYHH 326 HSP 9 Score: 65.0846 bits (157), Expect = 4.907e-10 Identity = 72/267 (26.97%), Postives = 125/267 (46.82%), Query Frame = 1
Query: 2284 VKSQAFYWVVIVLVFLNTGVLTSE--HYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGV-SVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKF-----NFDKKAKPRS--------------------NFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSS----MLSCLYYVILFICGNYILLNVFLAIAVDN 2988
V+ + F W ++ V +++ L E H Q L+ N N +F +F+LE ++K+ G YF ++N D +V + + + P L V R R LR + ++ ++ +L A++ I S+LV+ LF ++FS+ G+QLF GKF D+K P NFD+ + L + Q+ T E W EVM D + S + S +++ Y+V+ I G++ +LN+F+ + +DN
Sbjct: 790 VEHRYFEWFILFTVMVSSFTLVFEDIHLHQKPDLERALNFLNFLFAAIFSLEFILKVIGFGFVSYFTSVWNCLDALIVSVCVSVACLFEN---PNLSVFRSFRTVRGLRPLRAISRLGGMKVVINALFAAIPGIGSVLVVSMLFWLMFSISGVQLFAGKFYKCVNAEDEKLSPSVIPNKTACLDHPDYRWVNANVNFDNVINGFLALLQVATYEGWMEVMADAVDSTKIDQQPSYEANLIAYAYFVVFIIVGSFFVLNLFVGVIIDN 1053 HSP 10 Score: 62.3882 bits (150), Expect = 3.954e-9 Identity = 57/205 (27.80%), Postives = 90/205 (43.90%), Query Frame = 1
Query: 943 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGG---PDV-KALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELF 1545
QI KR P S RP + FR +V FE IL I N + D + + + V + IF E ++KI+A +H Y + W++ DF++V+ ++ L +E P + + LR FRV R LR+V ++ ++ +I+ +M LF+I L V+ IYAIIG+ F
Sbjct: 1079 VQILMAAAKRKPP---SNRLRPT---------DCFRGKLFDLVSSNQFEVFILTVIMCNMGMMMVQ----HYDQPPLTTVIGN--YVLVGIFLLEAIIKIIAMR--LH---YFKKAWSIFDFVVVVSSIVGMYLGMSTESAVVSPGLLRVLRVFRVARLLRVVQFAKRIRQLLVAIIISMPALFNIGTLLFLVMFIYAIIGMSSF 1260 HSP 11 Score: 60.4622 bits (145), Expect = 1.231e-8 Identity = 67/256 (26.17%), Postives = 139/256 (54.30%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVM---IQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRS--NFDSFVQSLLTVFQILTGEDWNEVM-------------YDGIRSYGNLGKSSMLSCLYYVILFICGNY-ILLNVFLAIAVDNL 2991
LV S F ++ ++ N G++ +HY Q N + V +F LE +IK+ ++ + YF ++ FDF VV+ SI+ + + ++ + P + VLR R+ R+ +V ++ +R L+ +++ SM ++ ++ LLFL + I++++GM FG N K+ NF++F S++ +F++ TG WN+++ + G+ + GN G + ++Y++ +I + I++N+++A+ +DN+
Sbjct: 1108 LVSSNQFEVFILTVIMCNMGMMMVQHYDQPPLTTVI---GNYVLVGIFLLEAIIKIIAMRLH-YFKKAWSIFDFVVVVSSIVGMYLGMSTESAVVSPGLLRVLRVFRVARLLRVVQFAKRIRQLLVAIIISMPALFNIGTLLFLVMFIYAIIGMSSFG---NIKKQGALNDLVNFETFSSSIILIFRLGTGTGWNDILDALVVQPPHCDPNFGGLPN-GNCGFP--IGAVFYLVTYIVSVFLIIVNMYIAVLLDNV 1353
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Nematostella
Match: EDO35661 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKR1]) HSP 1 Score: 219.935 bits (559), Expect = 3.853e-57 Identity = 218/761 (28.65%), Postives = 370/761 (48.62%), Query Frame = 1
Query: 3403 ICNHPHFGNIVLVCIMVSSAMLAAEDP-LDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSI---ISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELD-------KNQRKCIEFALKAKPVRRYI-PKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALK-FDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGT-----NNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNI---MLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLI-INLFVAVIMDNFDYLTRDWSI-LGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKR 5616
+ H F I+L I SS LA ED LD++ + ++L + LF +FTVE+ LK I G + + NILD ++V+ SI ++ ND I+ ++ LR LR RPLRAI+R +G+K V+ ++ A+ IGN++LV + +F+++GVQ+F GKF C D C + ++ N W N+ +NFD V L L V+TFEGW ++ ++D+ K D I N +F++ +II+ FF +N+F+G +I F Q ++ +D +N ++ A KP +R P+ F+ ++ ++ SR FE I + I +N + + ++ +D +Q+ LN++FT VF +E +L++ A K YF + WNVFDF+IV+ S I II +++ + + R F R GIR LL++ V S AL + L+ ++ FIYA+IGM +FG + K+ + +N NF+TF + ++LFR T W +I ++ PD CD Y R +GN CG+ + P ++ +++ FLI IN+++AVI++N++ + I + ++ F ++W +DP A I + D+ + ++ L K P++ AC L N+PL + L ALV+ +I + VD +E ++V++++ +R
Sbjct: 823 LVEHKVFEGIILFLIAASSISLAFEDVYLDSKPTLKQVLQILNILFAVIFTVEMLLKWIGLGF----KTYFTNPWNILDFVIVIVSIMVSLATIFGNDQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVDEGGE---KCPASVVPNKTVCLS----NGYRWENSNINFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDNFNQLKQQMEAVGSMDVFLTSTQRNWMNALKSAATKKPKKRIRRPQNKFQGELYDMVQSRKFEVFIMLFITINMVVMMVQHYDHLAVWSKQI---LNLIFTSVFILEAILRIIALR-KGYFLNPWNVFDFVIVISSIIGIIVENLQTSLVINPSLLRVVRVFRVGRLLRFFEAAR---------GIRRLLFSLVISTPALFNIGALLFLIIFIYAIIGMSIFGHV-----KKTEALNDVVNFETFGSSFVLLFRLMTSAGWNDILDPLMISEPD--CDP-------NY------RGLPSGN--------------------------------CGNKYMAPIYLGSFVVIIFLILINMYIAVILENYNQVMEQEKIGITNEDIELFYQMWELFDPNATQYIPYADLSDFVHQMEGNLRIPK--PNKAACALL---NIPLVKGDKIHCLDLLQALVK---RIVSGFEDVD--SEGFKIVMQRMEER 1497 HSP 2 Score: 161.384 bits (407), Expect = 3.206e-39 Identity = 115/371 (31.00%), Postives = 184/371 (49.60%), Query Frame = 1
Query: 1012 RALFCLTLRNPFRKFCIKIVEWK-PFEY-----LILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRA---FRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDD------FHSSGFKYMCKDNKNETSRWSG-PNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPW--IYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAK---KRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEEND 2061
++L+ NP R+F +K++ + P + +L TI NC LA P PE+ E VF I+T E KI+A GF +H AYLR+ WN LDF++VI+G ++ PDV L FRV R LR +S + L+ ++N+++ +M L+ + +L LF I I+A+IG++LF G+L + C + P S + + +D +++G + C N G PN G TSFD+FG A+LT FQ IT++ W + N+ + PW +YF +I G FF++NLVL V++ + E + +K + + ++ R + L + D+ DE N
Sbjct: 22 KSLYLFGPENPIRQFSLKLITNQYPLQLHNRHMFVLLTILVNCVFLAMTNP-PEQP-----------EYVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVILGNVTI--------SPDVANLSGIPTFRVFRALRTISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLFIGELRNKCALPVPENLSVPYRTYASNSSIWYLEDNEPILCGNTTGSR-TCPTNYTCLPHAGGNPNFGYTSFDHFGWALLTGFQLITLDFWENVY---NNVIYTMGPWYVVYFAVVIFFGPFFLVNLVLAVVAASYENEVKASKMETEEERKEQKRVASSYSVRRASILSIVYGQGDVIPDEPNS 368 HSP 3 Score: 127.102 bits (318), Expect = 8.069e-29 Identity = 92/312 (29.49%), Postives = 155/312 (49.68%), Query Frame = 1
Query: 1063 KIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPD----VKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCST-SVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSW---------PWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRG 1956
++VE K FE +ILF I A+ +LA Y + T+ L+ + ++F VIFT E +LK + GF Y N WN+LDF+IVI+ S ++S + G D +++LR R RPLR +S ++VV+ S++ A+ + ++ L+ L +I++I+G+++F GK + S VP T ++ GY RW N+ +FD L + Q T EGW +IM D+ + +++FV II+G+FF +NL +GV+ F++ +++ + G
Sbjct: 822 RLVEHKVFEGIILFLIAASSISLAFEDVYLDSKP-TLKQVLQILNILFAVIFTVEMLLKWIGLGF----KTYFTNPWNILDFVIVIV---SIMVSLATIFGNDQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVDEGGEKCPASVVPNKTVCLSNGY----------------------RWENSNI---NFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDNFNQLKQQMEAVG 1100 HSP 4 Score: 117.472 bits (293), Expect = 6.721e-26 Identity = 95/342 (27.78%), Postives = 154/342 (45.03%), Query Frame = 1
Query: 4342 RYRVWWLITSRPFEYIIFVLIMLNTISLALK---FDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGK-----ITTENEKEMKEI---------------NRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILG 5298
RY+V L+ + FE II LI ++ISLA + D +P +QV+ LN++F +FTVE LLK GFK YF++ WN+ DF+IV+ S I + + G D++ I R R R ++ +SR EG++ ++ + + + + V L+ +M + I++++G+Q+FG + EK + N N NF T Q L L + AT E W IM DA+ D+ E N++ AY +F+ F ++ +F +NLF+ VI+DNF+ L + +G
Sbjct: 817 RYKVRRLVEHKVFEGIILFLIAASSISLAFEDVYLDSKPT-LKQVLQILNILFAVIFTVEMLLKWIGLGFKTYFTNPWNILDFVIVIVS-IMVSLATIFGN------DQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVDEGGEKCPASVVPNKTVCLSNGYRWENSNINFDTVDQGFLALLQVATFEGWMEIM----EDAVDATKIDEQPIEENNVS----------------------------------------------AYLFFVVFIILGTFFTLNLFIGVIIDNFNQLKQQMEAVG 1100 HSP 5 Score: 102.064 bits (253), Expect = 3.549e-21 Identity = 72/209 (34.45%), Postives = 114/209 (54.55%), Query Frame = 1
Query: 4381 EYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCL----PDAM 4995
E I V I+LNT+ ++++ + V++ N VFT +F +E +LKL A GF Y AWN+FD I+V+ S +D I VN + G I+ R FR++R++KL + +LL T KS AL + +++ ++ +I+AV+GMQ+ G T +K I R NF+ FP + +++FR GE W + C+ P AM
Sbjct: 506 EIFIIVCILLNTLVMSIEHPRLEDPLLTVVNISNEVFTFIFLLEMILKLIALGFLGYIRVAWNIFDGIVVIISIVDFI---VNKFVPDAGGT---GISVLRTFRLLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNSYTP-DKFGGSIPR-WNFKDFPHSFMMIFRVLCGE-WIEPLWDCMLATGPVAM 705 HSP 6 Score: 99.7525 bits (247), Expect = 1.758e-20 Identity = 81/221 (36.65%), Postives = 132/221 (59.73%), Query Frame = 1
Query: 2311 VIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVM--IQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDK--KAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLN 2961
+IV + LNT V++ EH R L + N +N +F +F LEM++K+ +LG Y +N FD VVI SI++ ++ DA G+SVLR RLLRV K+ + WS++ +L+ ++ S+ ++ +L V+L + + IF+++GMQL G + DK + PR NF F S + +F++L GE W E ++D + + G ++ L +V FI GN+I+LN
Sbjct: 509 IIVCILLNTLVMSIEHPRLEDPLLTVVNISNEVFTFIFLLEMILKLIALGFLGYIRVAWNIFDGIVVIISIVDFIVNKFVPDA-GGTGISVLRTFRLLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNSYTPDKFGGSIPRWNFKDFPHSFMMIFRVLCGE-WIEPLWDCMLATGP------VAMLLFVPAFILGNFIILN 721 HSP 7 Score: 73.559 bits (179), Expect = 1.303e-12 Identity = 44/165 (26.67%), Postives = 86/165 (52.12%), Query Frame = 1
Query: 1060 IKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM--SEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFS 1548
+K K E I+ I N ++ P E T+ + + VF IF E +LK++A GF+ Y+R WN+ D ++VII ++ +++K GG + LR FR+LR L+L ++ ++ +I +++ L ++ ++ ++ I+A++G++L
Sbjct: 497 LKFTNGKVMEIFIIVCILLNTLVMSIEHPRLEDPLLTVVNISNE---VFTFIFLLEMILKLIALGFL----GYIRVAWNIFDGIVVIISIVDFIVNKFVPDAGGTGISVLRTFRLLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLG 654 HSP 8 Score: 69.707 bits (169), Expect = 2.058e-11 Identity = 75/280 (26.79%), Postives = 137/280 (48.93%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDS------FQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLG-------VSVLRCARLLRVFKVTRYWS---SLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFN--FDKKAK--PRS--------------------NFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYG----NLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDN 2988
LV+ + F +++ L+ ++ L E ++LDS NI+F V+FT+EML+K LG + Y F ++IL+ V++ M L ++ +R R LR F+ R S ++ ++ SLL ++ I ++L++ +F +IFS++G+Q+FGGKF D+ + P S NFD+ Q L + Q+ T E W E+M D + + + ++++ + L++V+ I G + LN+F+ + +DN
Sbjct: 823 LVEHKVFEGIILFLIAASSISLAFE----DVYLDSKPTLKQVLQILNILFAVIFTVEMLLKWIGLGFKTY----------FTNPWNILDFVIVIVSIMVSLATIFGNDQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVDEGGEKCPASVVPNKTVCLSNGYRWENSNINFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDN 1088 HSP 9 Score: 66.2402 bits (160), Expect = 2.282e-10 Identity = 89/341 (26.10%), Postives = 167/341 (48.97%), Query Frame = 1
Query: 3316 AKEKIKPIPNASSFFIFGPNNKFRKFC-HFICN-HP-HFGN---IVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQS-CN-DVSKNTHISCR----GQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTL-FAVSTFE--GWP---GVLYKSIDSFKEDYSG-IYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRK 4281
K ++ + S ++FGP N R+F I N +P N VL+ I+V+ LA +P + +Y+F +++T+E+ K+I G H A+ R N LD +VV+ ++ I+ D ++ + + RV R LR I+ KGLK +V ++V++K + ++M++T +FA+IG+QLF G+ ++ C V +N + R I+Y E + + N P N+ +P+A F ++F+ GW G ++D ++ Y+ IY P +++ I FF++N+ + V +++ E + E ++ ++K
Sbjct: 11 GKTQVYRFNRSKSLYLFGPENPIRQFSLKLITNQYPLQLHNRHMFVLLTILVNCVFLAMTNPPEQP----------EYVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVILGNVT--ISPD-VANLSGIPTFRVFRALRTISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLFIGELRNKCALPVPENLSVPYRTYASNSSIWYLEDNEPILCGNTTGSRTCPTNYTCLPHAGGNPNFGYTSFDHFGWALLTGFQLITLDFWENVYNNVIYTMGPWYVVYFAVVIFFGPFFLVNLVLAVVAASYENEVKASKMETEEERKEQK 338 HSP 10 Score: 58.151 bits (139), Expect = 7.072e-8 Identity = 45/155 (29.03%), Postives = 74/155 (47.74%), Query Frame = 1
Query: 4390 IFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFK----NYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF 4842
+ + I++N + LA+ + Y VF ++T+E K+ A GF Y D WN DFI+V+ + I D N L I FR+FR +R + S +G++ ++ T + S + L V +L + I+A+IGMQ+F
Sbjct: 56 VLLTILVNCVFLAMTNPPEQPEY---------VFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVILGNVTISPDVAN----------LSGIPTFRVFRALRTI---SAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLF 188
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517]) HSP 1 Score: 1638.62 bits (4242), Expect = 0.000e+0 Identity = 954/1748 (54.58%), Postives = 1181/1748 (67.56%), Query Frame = 1
Query: 1018 LFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVM--MESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGG------AHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERL-IKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAI------RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVN----------------------------GTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYLPSHLGAE----RRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSP 6084
L CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TC + + E P PC+ G C ++ W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E +G ++ K + +SE D + EG A +S++ +F ++ VKSQ FYW+VI LVFLNT + SEH+RQ WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F QSLLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S +K+E E +E + K + N P ++EK +E++ +KS +G+ + M E E Y D +++ + + R +S++ KEK P+P A +FF+F NKFR CH I NH F N++L I++SS LAAEDP+ +S RN+IL Y D++FT +FT+EI LK+ YG H G+FCR+ NILDL+VV S+IS I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GKF C D SK T CRG YI Y + D+ K + R W N+ NFD+V M+ LFAVSTFEGWPG+LY++IDS ED IYN R ++SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++F LI+LNTI LA++ Q + + M+ LNM+FTG+FTVE +LKL AF + YFSD WNVFDF+IV+GS ID+I +N G N+ R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI +++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C P+ C + G+ N + +CGS FA YF+SFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT L+IKTDG+ ++Q NEELR ++KKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K+++ + G ++ LSL GP I IS L E D+ K+ P +E RR+ +FG +N + S R S P+ + RP+ ++Q SP
Sbjct: 143 LLCLTLKNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGLNAEEKPAPCAPDGAYGRHC-----------TQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDKPRNLSM----PASENESVNTDNPPGG---DVEGETCCTRLARYSRRWNRLFRRKCRAA----------------VKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETR--RSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEAKERKKLARLASPKK--HEENEKPPLEEK----KSEKIELKSITSDGETNPATKISMDDCCGDENEEKNPYPANDYIGDDDEEEPEMPVGPRPRPLSDIHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRSPRVWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTKNFNDAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINPADSSSSSSSSSSSSSSSTSHPPVVRPMGLQNSEENAR-ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAL---RDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPC--------------------EKGSTNENSTA----------------------SEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTDGN-LEQANEELRAIVKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKVPPKTA-LSLQAGLRTLHDIGPEIRRAISGDLNVEEEMDKGMKE--PVSAASEDDIFRRSGGLFGNHVNYYNQ--SDGRSS--------------FPQSFTTQRPLHISQKGSP 1782 HSP 2 Score: 104.375 bits (259), Expect = 2.149e-21 Identity = 96/342 (28.07%), Postives = 158/342 (46.20%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLD-----FLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLI---------IIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
P P+ RA F + N FR C KIV F LILF I + +LAA P ++ + N L + VF +FT E +LK+ A+G +H G++ RN +N+LD ++ G+ S+ ++ VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK + D ++ C S Y+ D G +N + +FD+ M+ +F T EGW ++Y DS IY ++ II +FF+MN+ +G + F ++ E+ K + K + Q
Sbjct: 899 PMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPV--KNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINV-------VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKF----FYCTDSSKQTQAECRGSYIM-YKDGDVGKPGRSPRVWENSD------------FNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQ 1214
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517]) HSP 1 Score: 1624.76 bits (4206), Expect = 0.000e+0 Identity = 959/1742 (55.05%), Postives = 1188/1742 (68.20%), Query Frame = 1
Query: 1018 LFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVM--MESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERL-IKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAI------RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVN----------------------------GTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYLPSHLGAE----RRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSP 6084
L CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TC + + E P PC+ G C ++ W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AE D + + +E + + + + S +S + D+ ++ ET + + F SR R+WNR RR CR VKSQ FYW+VI LVFLNT + SEH+RQ WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F QSLLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S +K+E E +E + K + N P ++EK +E++ +KS +G+ + M E E Y D +++ + + R +S++ KEK P+P A +FF+F NKFR CH I NH F N++L I++SS LAAEDP+ +S RN+IL Y D++FT +FT+EI LK+ YG H G+FCR+ NILDL+VV S+IS I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GKF C D SK T CRG YI Y + D+ K + R W N+ NFD+V M+ LFAVSTFEGWPG+LY++IDS ED IYN R ++SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++F LI+LNTI LA++ Q + + M+ LNM+FTG+FTVE +LKL AF + YFSD WNVFDF+IV+GS ID+I +N G N+ R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI +++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C P+ C + G+ N + +CGS FA YF+SFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT L+IKTDG+ ++Q NEELR ++KKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K+++ + G ++ LSL GP I IS L E D+ K+ P +E RR+ +FG +N + S R S P+ + RP+ ++Q SP
Sbjct: 143 LLCLTLKNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGLNAEEKPAPCAPDGAYGRHC-----------TQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAE---DIDPENEEEGLDDDKPRNLSMPASENESVNTDNPPGGDVEGETCCTRLAIRISKSKF-----SRYSRRWNRLFRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETR--RSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEAKERKKLARLASPKK--HEENEKPPLEEK----KSEKIELKSITSDGETNPATKISMDDCCGDENEEKNPYPANDYIGDDDEEEPEMPVGPRPRPLSDIHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRSPRVWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTKNFNDAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINPADSSSSSSSSSSSSSSSTSHPPVVRPMGLQNSEENAR-ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAL---RDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPC--------------------EKGSTNENSTA----------------------SEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTDGN-LEQANEELRAIVKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKVPPKTA-LSLQAGLRTLHDIGPEIRRAISGDLNVEEEMDKGMKE--PVSAASEDDIFRRSGGLFGNHVNYYNQ--SDGRSS--------------FPQSFTTQRPLHISQKGSP 1791 HSP 2 Score: 103.99 bits (258), Expect = 2.897e-21 Identity = 96/342 (28.07%), Postives = 158/342 (46.20%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLD-----FLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLI---------IIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
P P+ RA F + N FR C KIV F LILF I + +LAA P ++ + N L + VF +FT E +LK+ A+G +H G++ RN +N+LD ++ G+ S+ ++ VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK + D ++ C S Y+ D G +N + +FD+ M+ +F T EGW ++Y DS IY ++ II +FF+MN+ +G + F ++ E+ K + K + Q
Sbjct: 908 PMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPV--KNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINV-------VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKF----FYCTDSSKQTQAECRGSYIM-YKDGDVGKPGRSPRVWENSD------------FNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQ 1223
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Medaka
Match: CACNA1D (calcium voltage-gated channel subunit alpha1 D [Source:NCBI gene;Acc:101171831]) HSP 1 Score: 1226.85 bits (3173), Expect = 0.000e+0 Identity = 706/1168 (60.45%), Postives = 843/1168 (72.17%), Query Frame = 1
Query: 2284 VKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNID-----EKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQS 5772
VKS FYW+VI+LVFLNT + SEHY Q WL Q+ AN + + LFTLEML+KMYSLG++ YF +FNRFD FVV I+E ++++ M PLG+SV RC RLLR+FKVTR+W+SL NLV SLL SMKSI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F Q+LLTVFQILTGEDWN VMYDGI +YG S M+ C+Y++ILFICGNYILLNVFLAIAVDNLAD S N +++ + E K NS+NV P + E D E +E D+ DE + + T +R+SE+ KEK PIP S+FFIF N FR CH + NH F N++LV IM+SS LAAEDP+ S+RN IL YFDY FT++FTVEI LK+ +G H GAFCR+ N+LDLLVV S++S+ I + AISVVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNIM+VT LL+FMFA IGVQLF GKF C D +K++ C+G YI Y+ D A + +R W N+ NFDNV AM+ LF VSTFEGWP +LYK+IDS +E+ IYN R +SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+ W+++ S FEY++FVLI+LNT+ LA++ Q + MD LNMVFTGVFTVE +LKL AF + Y DAWNVFD ++V+GS +DII V N ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLI MLFFIYAVIGMQ+FGKI + +INRNNNFQTFPQA+L+LFR ATGEAWQ IML CLP +CD+ SD YN R CGS FA YFISFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+WSEYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT LKIKT+G+ +DQ NEELRVVIKKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQ++FR++K+++ ++GM + Q+
Sbjct: 403 VKSVTFYWLVIILVFLNTLTIASEHYNQPDWLTEVQDVANKVLLALFTLEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELAIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETVTKRSTFDNFPQALLTVFQILTGEDWNTVMYDGIMAYGGPASSGMVVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQRE------------EEEAKKRRNSTNVHPLLTVQLPTETLLEADKEPYAAAESPGDDVDDEDNNDILPEVPTGPRP--------------------QRLSELTIKEKTPPIPQGSAFFIFSSTNPFRVLCHKLINHQIFTNLILVFIMLSSVSLAAEDPIRNFSARNIILGYFDYAFTAIFTVEILLKMTAFGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDDAKSSPEECKGTYILYSNGDTALPMIKERIWYNSDFNFDNVLMAMMALFTVSTFEGWPTLLYKAIDSNRENMGPIYNYRIEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSTGFEYVMFVLIILNTLCLAIQHYGQSHLFNYAMDILNMVFTGVFTVEMILKLIAFKPRGYVGDAWNVFDALVVIGSVVDIILSQVIVEPGNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDG---TQINRNNNFQTFPQAVLMLFRCATGEAWQEIMLACLPGKLCDSESD------YNPGEERT-------------------------------------CGSGFAIIYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGN-LDQANEELRVVIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKRRK---EQGMRFLQA 1488 HSP 2 Score: 453.751 bits (1166), Expect = 5.318e-131 Identity = 222/371 (59.84%), Postives = 271/371 (73.05%), Query Frame = 1
Query: 970 RTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP------------DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCY--SKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDI 2040
R + S N RP RALFCLTL NP R+ CI +VEWKPF+ IL +IFANC ALA P+P DSN+ N LEK+E F++IFT E +KI+A+G +MH +Y+RNGWN+LDF+IVI+GL S VL +++ DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H+TCY + E P PC+ S G C F+ + +C++ W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND++G PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI
Sbjct: 9 RFKKQGGSTNSRPPRALFCLTLNNPIRRACISLVEWKPFDIFILLSIFANCVALAIYIPFPGDDSNSTNQELEKVEYAFLIIFTIETFMKIIAYGLVMHQNSYVRNGWNMLDFVIVIVGLFSVVLEMITKDADHGGQSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCYVIQTGALAEEEPAPCAVS-GHGRHCL-FNGT----ICREG------WQGPNNGITNFDNFLFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDI 367 HSP 3 Score: 146.362 bits (368), Expect = 2.713e-34 Identity = 147/597 (24.62%), Postives = 278/597 (46.57%), Query Frame = 1
Query: 3352 SFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVV---LTSIISYPINNDA--------ISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGKFQSCNDVSKN----------THISCRGQYIYYNEADIAKVFVNKREWI---NNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEE---------YKNCELDKNQRKCIEFALKAKPV-------RRYIPKQSFRYRVW--W----------LITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
+ F NN R+ C + F +L+ I + LA P D +S N+ L +Y F +FT+E +K+I YGLV H ++ R+ N+LD ++V L S++ I DA ++ LR R LR + G+ + + +K++ ++ + L+ F ++A+IG++LF GK + V + +S G++ +N + + W N NFDN AMLT+F T EGW VLY D+ + +Y +++ +I +FF++N+ +G + F +E E+ + +L+++ + +++ +A+ + K++ ++R W W + S F +++ +L+ LNT+++A + QP +V D N V +FT+E L+K+ + G + YF +N FD +V G ++ I + + + I+ FR R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E + + + F FPQA+L +F+ TGE W +M
Sbjct: 24 ALFCLTLNNPIRRACISLVEWKPFDIFILLSIFANCVALAIYIPFPGDDSNSTNQELEKVEYAFLIIFTIETFMKIIAYGLVMHQNSYVRNGWNMLDFVIVIVGLFSVVLEMITKDADHGGQSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCYVIQTGALAEEEPAPCAVSGHGRHCLFNGT------ICREGWQGPNNGITNFDNFLFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVY---------FVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENDEEGDEEGKRNRKFRQWRRWNRLCRRKCRAAVKSVTFYWLVIILVFLNTLTIASEHYNQPDWLTEVQDVANKVLLALFTLEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELAIMSP-------LGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDET----VTKRSTFDNFPQALLTVFQILTGEDWNTVM 594 HSP 4 Score: 122.479 bits (306), Expect = 5.531e-27 Identity = 116/367 (31.61%), Postives = 173/367 (47.14%), Query Frame = 1
Query: 910 RPLNLAALTLSAQIASGGRKRTPARSQSGNPRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIY---------FVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
RP L+ LT+ +++TP P PQ A F + NPFR C K++ + F LIL I + +LAA P R+ + N L + F IFT E +LK+ AFG +H GA+ RN +NLLD L+V + L+S S VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK Y D SP C KG + M K+ W + +FDN +AM+ +F T EGW ++Y DS + IY F+ III +FF+MN+ +G + F ++ EK K + K + Q
Sbjct: 711 RPQRLSELTI--------KEKTP-------PIPQGSAFFIFSSTNPFRVLCHKLINHQIFTNLILVFIMLSSVSLAAEDPI--RNFSARNIILGYFDYAFTAIFTVEILLKMTAFGAFLHKGAFCRNYFNLLDLLVVGVSLVS--FGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKF----YRCTDDAKSSPEEC-----KGTYILYSNGDTALPMIKERI-----WYNSDF---NFDNVLMAMMALFTVSTFEGWPTLLYKAIDSNRENMGPIYNYRIEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQ 1041 HSP 5 Score: 89.7373 bits (221), Expect = 5.490e-17 Identity = 71/255 (27.84%), Postives = 138/255 (54.12%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPP-------LGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMYDGI-------RSYGNLGK----SSMLSCLYYVILFICGNYILLNVFLAIAVDN 2988
+V S F +V+ VL+ LNT L +HY QS + + N++F +FT+EM++K+ + R Y +N FD VVI S+++I++ Q P + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R +NF +F Q++L +F+ TGE W E+M + S N G+ S + +Y++ ++ ++++N+F+A+ +DN
Sbjct: 1068 VVNSTGFEYVMFVLIILNTLCLAIQHYGQSHLFNYAMDILNMVFTGVFTVEMILKLIAFKPRGYVGDAWNVFDALVVIGSVVDIILSQVIVEPGNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDGTQINRNNNFQTFPQAVLMLFRCATGEAWQEIMLACLPGKLCDSESDYNPGEERTCGSGFAIIYFISFYMLCAFLIINLFVAVIMDN 1322 HSP 6 Score: 86.6557 bits (213), Expect = 4.354e-16 Identity = 78/320 (24.38%), Postives = 142/320 (44.38%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM--------SEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWI----------------NDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEY++ I N LA Y + S+ N A++ + +VF +FT E +LK++AF P Y+ + WN+ D L+VI ++ +LS++ + R FRV+R ++L+S ++ ++ + +++ L ++ALL + IYA+IG+++F GK+ M++ T +N+ N N F F A+L +F+C T E W +IM + G + IYF+S ++ +F ++NL + V+ F
Sbjct: 1058 KNPYQYKFWYVVNSTGFEYVMFVLIILNTLCLAIQH-YGQ--SHLFNYAMDILNMVFTGVFTVEMILKLIAF----KPRGYVGDAWNVFDALVVIGSVVDIILSQVIVEPGNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVF-GKI---------AMVD-----GTQINR------------------NNN--------------FQTFPQAVLMLFRCATGEAWQEIMLACLPGKLCDSESDYNPGEERTCGSGFAIIYFISFYMLCAFLIINLFVAVIMDNF 1323 HSP 7 Score: 77.0258 bits (188), Expect = 3.811e-13 Identity = 61/257 (23.74%), Postives = 114/257 (44.36%), Query Frame = 1
Query: 4360 LITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINF----FRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF-GKI---------------------------------TTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
L+ +PF+ I + I N ++LA+ Q ++ + F +FT+E +K+ A+G +Y + WN+ DF+IV+ ++ + + ++ F R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F GK+ T E N NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 41 LVEWKPFDIFILLSIFANCVALAIYIPFPGDDSNSTNQELEKVEYAFLIIFTIETFMKIIAYGLVMHQNSYVRNGWNMLDFVIVIVGLFSVVLEMITKDADHGGQSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCYVIQTGALAEEEPAPCAVSGHGRHCLFNGTICREGWQGPNNGITNFDNFLFAMLTVFQCITMEGWTDV-LYWMNDAM 296 HSP 8 Score: 63.929 bits (154), Expect = 2.967e-9 Identity = 77/320 (24.06%), Postives = 139/320 (43.44%), Query Frame = 1
Query: 1048 RKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNT-INSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWP-------WIYFVSLIIIGSFFVMNLVLGVLSGEFS---------KEREKAKKR 1953
R+ C V+ F +L++ +F N +A+ Y + D T + K V + +FT E ++K+ + G AY + +N D +V G++ T+L +++ P + R R+LR ++ SL ++ S++ +M + + LL III++++G++LF GK + ++ T R ++FDNF A+LTVFQ +T E W +MY + + P IYF+ L I G++ ++N+ L + + +E E+AKKR
Sbjct: 396 RRKCRAAVKSVTFYWLVIILVFLNTLTIASEH-YNQPDWLTEVQDVANK---VLLALFTLEMLVKMYSLGL----QAYFVSLFNRFDCFVVCGGIVETILVELAIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNF----------------------------------------DETVTKR--------STFDNFPQALLTVFQILTGEDWNTVMY--DGIMAYGGPASSGMVVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQREEEEAKKR 657
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517]) HSP 1 Score: 1218.37 bits (3151), Expect = 0.000e+0 Identity = 727/1279 (56.84%), Postives = 897/1279 (70.13%), Query Frame = 1
Query: 2284 VKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERL-IKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAI------RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYLPSHLGAE----RRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSP 6084
VKSQ FYW+VI LVFLNT + SEH+RQ WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F QSLLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S +K+E E +E + K + N P ++EK +E++ +KS +G+ + M E E Y D +++ + + R +S++ KEK P+P A +FF+F NKFR CH I NH F N++L I++SS LAAEDP+ +S RN+IL Y D++FT +FT+EI LK+ YG H G+FCR+ NILDL+VV S+IS I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GKF C D SK T CRG YI Y + D+ K + R W N+ NFD+V M+ LFAVSTFEGWPG+LY++IDS ED IYN R ++SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++F LI+LNTI LA++ Q + + M+ LNM+FTG+FTVE +LKL AF + YFSD WNVFDF+IV+GS ID+I +NG N+ R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI +++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C P+ C + G+ N + +CGS FA YF+SFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT L+IKTDG+ ++Q NEELR ++KKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K+++ + G ++ LSL GP I IS L E D+ K+ P +E RR+ +FG +N + S R S P+ + RP+ ++Q SP
Sbjct: 559 VKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETR--RSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEAKERKKLARLASPKK--HEENEKPPLEEK----KSEKIELKSITSDGETNPATKISMDDCCGDENEEKNPYPANDYIGDDDEEEPEMPVGPRPRPLSDIHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRSPRVWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTKNFNDAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINGLQNSEENAR-ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAL---RDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPC--------------------EKGSTNENSTA----------------------SEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTDGN-LEQANEELRAIVKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKVPPKTA-LSLQAGLRTLHDIGPEIRRAISGDLNVEEEMDKGMKE--PVSAASEDDIFRRSGGLFGNHVNYYNQ--SDGRSS--------------FPQSFTTQRPLHISQKGSP 1763 HSP 2 Score: 468.003 bits (1203), Expect = 1.363e-132 Identity = 222/367 (60.49%), Postives = 269/367 (73.30%), Query Frame = 1
Query: 1018 LFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVM--MESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGK 2079
L CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TC + + E P PC+ G C ++ W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ND+V WPW+YFV+LIIIGSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E +G ++ K
Sbjct: 143 LLCLTLKNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGLNAEEKPAPCAPDGAYGRHC-----------TQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVDYRWPWVYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDK 498 HSP 3 Score: 104.375 bits (259), Expect = 2.218e-21 Identity = 96/342 (28.07%), Postives = 158/342 (46.20%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLD-----FLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLI---------IIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
P P+ RA F + N FR C KIV F LILF I + +LAA P ++ + N L + VF +FT E +LK+ A+G +H G++ RN +N+LD ++ G+ S+ ++ VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK + D ++ C S Y+ D G +N + +FD+ M+ +F T EGW ++Y DS IY ++ II +FF+MN+ +G + F ++ E+ K + K + Q
Sbjct: 908 PMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPV--KNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINV-------VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKF----FYCTDSSKQTQAECRGSYIM-YKDGDVGKPGRSPRVWENSD------------FNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQ 1223 HSP 4 Score: 97.4413 bits (241), Expect = 2.661e-19 Identity = 79/320 (24.69%), Postives = 140/320 (43.75%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----SEGGPDVKA--LRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWI-----------------NDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEYL+ I N LA + N A+ + ++F +FT E +LK++AF P Y + WN+ DFLIVI +I +LS++ SE + R FRV+R ++L+S ++ ++ + +++ L ++ALL + + IYA+IG+++F GK+ + + + N+N +F F A+L +F+C T E W +IM ++ G + IYFVS ++ +F ++NL + V+ F
Sbjct: 1240 KNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQH---HGQTKNFNDAMNILNMLFTGLFTVEMILKLIAF----KPRGYFSDPWNVFDFLIVIGSIIDVILSEINGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMF-GKI----------------------------------ALRDLSQINRN------------NNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNF 1505 HSP 5 Score: 92.4337 bits (228), Expect = 7.657e-18 Identity = 59/211 (27.96%), Postives = 109/211 (51.66%), Query Frame = 1
Query: 4339 FRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
FR + + S+ F +++ L+ LNT+++A + +QPQ V D N V +FT E LLK+ + G + YF +N FD +V G ++ I + + I+ R R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E R + F FPQ++L +F+ TGE W ++M
Sbjct: 551 FRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSP-------LGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE------TRRSTFDNFPQSLLTVFQILTGEDWNSVM 748 HSP 6 Score: 85.1149 bits (209), Expect = 1.242e-15 Identity = 76/273 (27.84%), Postives = 125/273 (45.79%), Query Frame = 1
Query: 3376 NKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVL----TSIISYPINNDAISXXXXXXXXXXXXXXXA------INRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGKF-QSC-------NDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
N R+ C I F I+L+ I + LA P D ++ N L +YLF +FTVE LKVI YGL+FH A+ R+ N+LD ++V+ ++I+ D + + ++ LRA + G+ + + +K++ ++ + L+ F ++A+IG++LF GK ++C N K + G Y + + + V + NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 150 NPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGLNAEEKPAPCAPDGAYGRHCTQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVDYRWPWVY 422 HSP 7 Score: 85.1149 bits (209), Expect = 1.374e-15 Identity = 64/259 (24.71%), Postives = 115/259 (44.40%), Query Frame = 1
Query: 4330 KQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVL-GSFIDIIYDHVNGTNNNHRGDRL--ISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF------------------------------GKITTENEKEMK-----EINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
K R ++ +PFE II + I N ++LA+ + ++ + +F +FTVE LK+ A+G Y + WN+ DFIIV+ G F I+ G G + + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G+ T+N + + + NF F A+L +F+ T E W +++
Sbjct: 149 KNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGLNAEEKPAPCAPDGAYGRHCTQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVL 407 HSP 8 Score: 83.9593 bits (206), Expect = 3.262e-15 Identity = 67/256 (26.17%), Postives = 137/256 (53.52%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAM------PPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMY------------DGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ L+ LNT L +H+ Q+ + N N++F LFT+EM++K+ + R YF +N FDF +VI SI+++++ + + + + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R +NF +F Q++L +F+ TGE W E+M S + S + +Y+V ++ ++++N+F+A+ +DN
Sbjct: 1250 VVNSTYFEYLMFTLILLNTICLAMQHHGQTKNFNDAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNF 1505 HSP 9 Score: 75.0998 bits (183), Expect = 1.366e-12 Identity = 75/294 (25.51%), Postives = 131/294 (44.56%), Query Frame = 1
Query: 1045 FRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMY-WINDSVGMSWP----WIYFVSLIIIGSFFVMNLVLGV 1908
FR+ C V+ + F +L++F +F N +A+ R + + V + +FT E +LK+ + G AY + +N D +V G++ T+L + P + LR R+LR ++ SL ++ S++ ++ + + LL III++++G++LF GK N +ET R ++FDNF ++LTVFQ +T E W +MY I G S+P IYF+ L I G++ ++N+ L +
Sbjct: 551 FRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEH---HRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGL----QAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF------------------------------------------NFDETRR--------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAI 787
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517]) HSP 1 Score: 1213.75 bits (3139), Expect = 0.000e+0 Identity = 725/1279 (56.68%), Postives = 895/1279 (69.98%), Query Frame = 1
Query: 2284 VKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERL-IKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAI------RRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLI-SLISPTLVTTNECDEKDKDYLPSHLGAE----RRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSP 6084
VKSQ FYW+VI LVFLNT + SEH+RQ WL Q+ AN + + LFT EML+KMYSLG++ YF +FNRFD FVV ILE ++++T M PLG+SVLRC RLLR+FK+TRYW+SL NLV SLL S++SI SLL+LLFLFI+IFSLLGMQLFGGKFNFD+ RS FD+F QSLLTVFQILTGEDWN VMYDGI +YG ML C+Y++ILFICGNYILLNVFLAIAVDNLAD S +K+E E +E + K + N P ++EK +E++ +KS +G+ + M E E Y D +++ + + R +S++ KEK P+P A +FF+F NKFR CH I NH F N++L I++SS LAAEDP+ +S RN+IL Y D++FT +FT+EI LK+ YG H G+FCR+ NILDL+VV S+IS I + AI+VVKILRVLRVLRPLRAINRAKGLK VVQCV VA+++IGNI++VT LL+FMFA IGVQLF GKF C D SK T CRG YI Y + D+ K + R W N+ NFD+V M+ LFAVSTFEGWPG+LY++IDS ED IYN R ++SIF+I YII+IAFFM+NIFVGFVIVTFQ++GE+EYKNCELDKNQR+C+E+ALKA+P+RRYIPK ++Y+VW+++ S FEY++F LI+LNTI LA++ Q + + M+ LNM+FTG+FTVE +LKL AF ++YF DAWN FD +IV+GS +DI VNG N+ R ISI FFRLFRVMRLVKLLSRGEGIRTLLWTF+KSFQALPYVALLIVMLFFIYAVIGMQMFGKI +++ +INRNNNFQTFPQA+L+LFR ATGEAWQ IML C P+ C + G+ N + +CGS FA YF+SFYM+C+FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF R+W+EYDPEAKGRIKHLDVVTLLR+I PPLGFGK CPHR AC LV MNMPLNSDGTVMFNATLFALVRT L+IKTDG+ ++Q NEELR ++KKIWKRTS K+LDQVVPPAG+D+VTVGKFYATFLIQE+FR++K+++ + G ++ LSL GP I IS L E D+ K+ P +E RR+ +FG +N + S R S P+ + RP+ ++Q SP
Sbjct: 604 VKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETR--RSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEAKERKKLARLASPKK--HEENEKPPLEEK----KSEKIELKSITSDGETNPATKISMDDCCGDENEEKNPYPANDYIGDDDEEEPEMPVGPRPRPLSDIHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRSPRVWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTKNFNDAMNILNMLFTGLFTVEMILKLIAFKPRHYFVDAWNTFDALIVVGSIVDIAITEVNGLQNSEENAR-ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAL---RDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPC--------------------EKGSTNENSTA----------------------SEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTDGN-LEQANEELRAIVKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKVPPKTA-LSLQAGLRTLHDIGPEIRRAISGDLNVEEEMDKGMKE--PVSAASEDDIFRRSGGLFGNHVNYYNQ--SDGRSS--------------FPQSFTTQRPLHISQKGSP 1808 HSP 2 Score: 461.455 bits (1186), Expect = 1.677e-130 Identity = 219/367 (59.67%), Postives = 267/367 (72.75%), Query Frame = 1
Query: 1018 LFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEG-----------GPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVM--MESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGK 2079
L CLTL+NP R+ CI IVEWKPFE +IL TIFANC ALA P+PE DSN NS LE++E +F++IFT E LK++A+G + HP AYLRNGWNLLDF+IV++GL S +L + ++G G DVKALRAFRVLRPLRLVSG+PSLQVV+NSI++AMVPL HIALL LFVIIIYAIIGLELF GK+H TC + + E P PC+ G C ++ W GPN GIT+FDNF AMLTVFQCITMEGWT ++YW+ D++G PW+YFVSL+I GSFFV+NLVLGVLSGEFSKEREKAK RG +QK RE+ Q +ED++GYLDWI AEDI + E +G ++ K
Sbjct: 165 LLCLTLKNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGLNAEEKPAPCAPDGAYGRHC-----------TQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDK 520 HSP 3 Score: 104.375 bits (259), Expect = 2.136e-21 Identity = 96/342 (28.07%), Postives = 158/342 (46.20%), Query Frame = 1
Query: 1000 PRPQ-RALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLD-----FLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLI---------IIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQ 1980
P P+ RA F + N FR C KIV F LILF I + +LAA P ++ + N L + VF +FT E +LK+ A+G +H G++ RN +N+LD ++ G+ S+ ++ VK LR RVLRPLR ++ L+ V+ + A+ + +I ++ + ++A IG++LF GK + D ++ C S Y+ D G +N + +FD+ M+ +F T EGW ++Y DS IY ++ II +FF+MN+ +G + F ++ E+ K + K + Q
Sbjct: 953 PMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPV--KNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINV-------VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKF----FYCTDSSKQTQAECRGSYIM-YKDGDVGKPGRSPRVWENSD------------FNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQ 1268 HSP 4 Score: 92.4337 bits (228), Expect = 7.814e-18 Identity = 59/211 (27.96%), Postives = 109/211 (51.66%), Query Frame = 1
Query: 4339 FRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIM 4971
FR + + S+ F +++ L+ LNT+++A + +QPQ V D N V +FT E LLK+ + G + YF +N FD +V G ++ I + + I+ R R++R+ K+ + L+ + + S +++ + LL+ + I++++GMQ+FG +E R + F FPQ++L +F+ TGE W ++M
Sbjct: 596 FRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSP-------LGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE------TRRSTFDNFPQSLLTVFQILTGEDWNSVM 793 HSP 5 Score: 88.5817 bits (218), Expect = 1.110e-16 Identity = 74/320 (23.12%), Postives = 137/320 (42.81%), Query Frame = 1
Query: 1036 RNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKM-----SEGGPDVKA--LRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWI-----------------NDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEF 1923
+NP++ +V FEYL+ I N LA + N A+ + ++F +FT E +LK++AF P Y + WN D LIV+ ++ ++++ SE + R FRV+R ++L+S ++ ++ + +++ L ++ALL + + IYA+IG+++F GK+ + + + N+N +F F A+L +F+C T E W +IM ++ G + IYFVS ++ +F ++NL + V+ F
Sbjct: 1285 KNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQH---HGQTKNFNDAMNILNMLFTGLFTVEMILKLIAF----KPRHYFVDAWNTFDALIVVGSIVDIAITEVNGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMF-GKI----------------------------------ALRDLSQINRN------------NNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNF 1550 HSP 6 Score: 87.4261 bits (215), Expect = 2.964e-16 Identity = 68/267 (25.47%), Postives = 120/267 (44.94%), Query Frame = 1
Query: 4330 KQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKF---DKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGF----KNYFSDAWNVFDFIIVL-GSFIDIIYDHVNGTNNNHRGDRL--ISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMF------------------------------GKITTENEKEMK-----EINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAM 4995
K R ++ +PFE II + I N ++LA+ + ++ + +F +FTVE LK+ A+G Y + WN+ DFIIV+ G F I+ G G + + R FRV+R ++L+S ++ +L + +K+ L ++ALL++ + IYA+IG+++F G+ T+N + + + NF F A+L +F+ T E W ++ L+ + DAM
Sbjct: 171 KNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGLNAEEKPAPCAPDGAYGRHCTQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDV-LYWMQDAM 436 HSP 7 Score: 85.8853 bits (211), Expect = 6.922e-16 Identity = 76/273 (27.84%), Postives = 125/273 (45.79%), Query Frame = 1
Query: 3376 NKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPL--DAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVL----TSIISYPINNDAISXXXXXXXXXXXXXXXA------INRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEF---MFAVIGVQLFNGKF-QSC-------NDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIY 4125
N R+ C I F I+L+ I + LA P D ++ N L +YLF +FTVE LKVI YGL+FH A+ R+ N+LD ++V+ ++I+ D + + ++ LRA + G+ + + +K++ ++ + L+ F ++A+IG++LF GK ++C N K + G Y + + + V + NFDN AMLT+F T EGW VLY D+ + +Y
Sbjct: 172 NPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGLNAEEKPAPCAPDGAYGRHCTQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVY 444 HSP 8 Score: 84.7297 bits (208), Expect = 1.864e-15 Identity = 66/256 (25.78%), Postives = 135/256 (52.73%), Query Frame = 1
Query: 2281 LVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAM------PPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPR-SNFDSFVQSLLTVFQILTGEDWNEVMY------------DGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNL 2991
+V S F +++ L+ LNT L +H+ Q+ + N N++F LFT+EM++K+ + R YF +N FD +V+ SI++I + + + + + ++ R R++R+ K+ +R L+ + + S +++ + +L+ + I++++GMQ+FG D R +NF +F Q++L +F+ TGE W E+M S + S + +Y+V ++ ++++N+F+A+ +DN
Sbjct: 1295 VVNSTYFEYLMFTLILLNTICLAMQHHGQTKNFNDAMNILNMLFTGLFTVEMILKLIAFKPRHYFVDAWNTFDALIVVGSIVDIAITEVNGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNF 1550 HSP 9 Score: 75.485 bits (184), Expect = 1.259e-12 Identity = 75/294 (25.51%), Postives = 131/294 (44.56%), Query Frame = 1
Query: 1045 FRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGP-DVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMY-WINDSVGMSWP----WIYFVSLIIIGSFFVMNLVLGV 1908
FR+ C V+ + F +L++F +F N +A+ R + + V + +FT E +LK+ + G AY + +N D +V G++ T+L + P + LR R+LR ++ SL ++ S++ ++ + + LL III++++G++LF GK N +ET R ++FDNF ++LTVFQ +T E W +MY I G S+P IYF+ L I G++ ++N+ L +
Sbjct: 596 FRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEH---HRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGL----QAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF------------------------------------------NFDETRR--------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAI 832
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000000524.1 (SMESG000000524.1) HSP 1 Score: 4475.23 bits (11606), Expect = 0.000e+0 Identity = 2449/2471 (99.11%), Postives = 2462/2471 (99.64%), Query Frame = 1
Query: 943 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFXXXXXXXXXXXXXXXXXKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYXXXXXXXXXXXXFYPQNIPSNRCSNVXXXXXXXXXXXXXXNXXXXXXXXXXXXAFIYPLSRGDXXXXXXXXXXXHQRYQXXXXXXXXMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSXXXXXXXXXXLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSXXXXXXXXXXXXSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHXXXXXXXXXXXXXXXXXXXTIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV 8355
AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLK+I+YG++ H +FCR+ NN++DL V+L + +S+ +NDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRSQSSESPESIQRKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYSAQSSAESSEIQFYPQNIPSNRCSNVQIIDLDISLSSSQDNGDEFEYEGGEEEAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSSMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSPPPTPAPNTNLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSPPPEPAPRQELPSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHNNSSNSSNNNNANNNSNNATIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV
Sbjct: 71 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKMISYGVILHRNSFCRNLNNVIDLGVILIASLSHVTDNDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRSQSSESPESIQRKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYSAQSSAESSEIQFYPQNIPSNRCSNVQIIDLDISLSSSQDNGDEFEYEGGEEEAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSSMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSPPPTPAPNTNLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSPPPEPAPRQELPSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHNNSSNSSNNNNANNNSNNATIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV 2541 HSP 2 Score: 164.851 bits (416), Expect = 6.466e-40 Identity = 71/72 (98.61%), Postives = 71/72 (98.61%), Query Frame = 1
Query: 253 MTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPGQ 468
MTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPP Q
Sbjct: 1 MTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPAQ 72
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000000524.1 (SMESG000000524.1) HSP 1 Score: 4474.85 bits (11605), Expect = 0.000e+0 Identity = 2449/2471 (99.11%), Postives = 2462/2471 (99.64%), Query Frame = 1
Query: 943 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFXXXXXXXXXXXXXXXXXKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYXXXXXXXXXXXXFYPQNIPSNRCSNVXXXXXXXXXXXXXXNXXXXXXXXXXXXAFIYPLSRGDXXXXXXXXXXXHQRYQXXXXXXXXMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSXXXXXXXXXXLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSXXXXXXXXXXXXSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHXXXXXXXXXXXXXXXXXXXTIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV 8355
AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLK+I+YG++ H +FCR+ NN++DL V+L + +S+ +NDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRSQSSESPESIQRKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYSAQSSAESSEIQFYPQNIPSNRCSNVQIIDLDISLSSSQDNGDEFEYEGGEEEAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSSMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSPPPTPAPNTNLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSPPPEPAPRQELPSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHNNSSNSSNNNNANNNSNNATIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV
Sbjct: 81 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKMISYGVILHRNSFCRNLNNVIDLGVILIASLSHVTDNDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRSQSSESPESIQRKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYSAQSSAESSEIQFYPQNIPSNRCSNVQIIDLDISLSSSQDNGDEFEYEGGEEEAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSSMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSPPPTPAPNTNLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSPPPEPAPRQELPSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHNNSSNSSNNNNANNNSNNATIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV 2551 HSP 2 Score: 186.422 bits (472), Expect = 1.962e-46 Identity = 81/82 (98.78%), Postives = 81/82 (98.78%), Query Frame = 1
Query: 223 MLNDRIYPNNMTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPGQ 468
MLNDRIYPNNMTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPP Q
Sbjct: 1 MLNDRIYPNNMTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPAQ 82
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000000524.1 (SMESG000000524.1) HSP 1 Score: 4418.61 bits (11459), Expect = 0.000e+0 Identity = 2417/2471 (97.81%), Postives = 2432/2471 (98.42%), Query Frame = 1
Query: 943 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFXXXXXXXXXXXXXXXXXKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYXXXXXXXXXXXXFYPQNIPSNRCSNVXXXXXXXXXXXXXXNXXXXXXXXXXXXAFIYPLSRGDXXXXXXXXXXXHQRYQXXXXXXXXMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSXXXXXXXXXXLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSXXXXXXXXXXXXSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHXXXXXXXXXXXXXXXXXXXTIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV 8355
AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLK+I+YG++ H +FCR+ NN++DL V+L + +S+ +NDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRS S S E + E+LIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYSAQSSAESSEIQFYPQNIPSNRCSNVQIIDLDISLSSSQDNGDEFEYEGGEEEAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSSMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSPPPTPAPNTNLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSPPPEPAPRQELPSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHNNSSNSSNNNNANNNSNNATIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV
Sbjct: 81 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKMISYGVILHRNSFCRNLNNVIDLGVILIASLSHVTDNDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRS---------------------QSSESPESIQRKEENLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYSAQSSAESSEIQFYPQNIPSNRCSNVQIIDLDISLSSSQDNGDEFEYEGGEEEAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSSMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSPPPTPAPNTNLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSPPPEPAPRQELPSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHNNSSNSSNNNNANNNSNNATIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV 2530 HSP 2 Score: 186.422 bits (472), Expect = 2.107e-46 Identity = 81/82 (98.78%), Postives = 81/82 (98.78%), Query Frame = 1
Query: 223 MLNDRIYPNNMTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPGQ 468
MLNDRIYPNNMTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPP Q
Sbjct: 1 MLNDRIYPNNMTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPAQ 82
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000000524.1 (SMESG000000524.1) HSP 1 Score: 4418.61 bits (11459), Expect = 0.000e+0 Identity = 2417/2471 (97.81%), Postives = 2432/2471 (98.42%), Query Frame = 1
Query: 943 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFXXXXXXXXXXXXXXXXXKEEKVVSPVYSSGYSDEEDRISTESLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYXXXXXXXXXXXXFYPQNIPSNRCSNVXXXXXXXXXXXXXXNXXXXXXXXXXXXAFIYPLSRGDXXXXXXXXXXXHQRYQXXXXXXXXMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSXXXXXXXXXXLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSXXXXXXXXXXXXSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHXXXXXXXXXXXXXXXXXXXTIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV 8355
AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLK+I+YG++ H +FCR+ NN++DL V+L + +S+ +NDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRS S S E + E+LIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYSAQSSAESSEIQFYPQNIPSNRCSNVQIIDLDISLSSSQDNGDEFEYEGGEEEAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSSMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSPPPTPAPNTNLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSPPPEPAPRQELPSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHNNSSNSSNNNNANNNSNNATIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV
Sbjct: 71 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKMISYGVILHRNSFCRNLNNVIDLGVILIASLSHVTDNDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRS---------------------QSSESPESIQRKEENLIYVRRKSKDRYKGQSSHNRIGTVRPSNIDSRRYSNKERVTNNQDIRYYKGSPNEYSAQSSAESSEIQFYPQNIPSNRCSNVQIIDLDISLSSSQDNGDEFEYEGGEEEAFIYPLSRGDTPSPAPPPPTAHQRYQSSSRTSSSMGQCLGRQSSRESLIDRGLVQPILFAQNQAVLLAGIGDCKQFVNTSLRRRLPDTPQFPAGKESVPFNPYEKSIANQLRNIRKSKIVNVPKLKYHQELIDNSQFPNESDNESYSADIAGLGTFNLEEWRNSPPPTPAPNTNLRYCPQRSNKETFRQEHQKNNFNRYDSLRQPERSSYLLHHQCSLEEEQIDSTEDYDEEIDQLKIQNQYEKDYNRYMLKYAPSNPRSQFVDPRNCCADPRVSRNPMPDLISSTDWLLEKCQNAPAMKNHTYQKNYKYPQLLTEETFSRRARMDANSPPPEPAPRQELPSQYVLSQQRESDEMEYLQMSQENIDKSFTNLRTRSKQYSDMGSQTHLEMSEPLLKQSIPNHLLSKSINPVFSPPIRPPYYEHLGGYGLHELKDSNVWSMRDENMSSILSRGATVRPFHPHGTKGVMRTHNNSSNSSNNNNANNNSNNATIRNQCEMQMKLPPPQDLLTNRKPSEKATYFLSVV 2520 HSP 2 Score: 164.851 bits (416), Expect = 7.067e-40 Identity = 71/72 (98.61%), Postives = 71/72 (98.61%), Query Frame = 1
Query: 253 MTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPGQ 468
MTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPP Q
Sbjct: 1 MTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPAQ 72
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Planmine SMEST
Match: SMESG000000524.1 (SMESG000000524.1) HSP 1 Score: 3380.88 bits (8765), Expect = 0.000e+0 Identity = 1817/1817 (100.00%), Postives = 1817/1817 (100.00%), Query Frame = 1
Query: 943 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEXXXXXXXXXXXXXXXETEGGAHHSQQQQYVFCFPLKSXXXXXXXXXXXXXXXXLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYXXXXXXXXXXXXXXXSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKXXXXXXXXXXXXXXXXXXXGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSXXXXXXXXXXXXXXXPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTXXXXXXXXXXXXXXXXXNGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISXXXXXXXXXXXXXXXAINRAKGLKRXXXXXXXXXKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPXXXXXXXXXXXXXXXXXXNIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFXXXXXXXXXXXXXXXXXKEEK 6393
AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRSQSSESPESIQRKEEK
Sbjct: 71 AQIASGGRKRTPARSQSGNPRPQRALFCLTLRNPFRKFCIKIVEWKPFEYLILFTIFANCCALAANTPYPERDSNTINSALEKIELVFIVIFTTECVLKILAFGFIMHPGAYLRNGWNLLDFLIVIIGLISTVLSKMSEGGPDVKALRAFRVLRPLRLVSGLPSLQVVMNSIMRAMVPLFHIALLALFVIIIYAIIGLELFSGKLHSTCYSKNDVMMESPVPCSTSVNKGYQCDDFHSSGFKYMCKDNKNETSRWSGPNMGITSFDNFGLAMLTVFQCITMEGWTQIMYWINDSVGMSWPWIYFVSLIIIGSFFVMNLVLGVLSGEFSKEREKAKKRGKYQKAREQMQFDEDVQGYLDWIGAAEDISDDEENDGKENGKESRFKLCGLCKSSEKSDDGDDQLSDKLDLETEGGAHHSQQQQYVFCFPLKSRRGRKWNRRCRRICRRLVKSQAFYWVVIVLVFLNTGVLTSEHYRQSIWLDSFQNTANIIFVVLFTLEMLIKMYSLGMRCYFDFMFNRFDFFVVIFSILEIVMIQTDAMPPLGVSVLRCARLLRVFKVTRYWSSLRNLVGSLLASMKSIVSLLVLLFLFIVIFSLLGMQLFGGKFNFDKKAKPRSNFDSFVQSLLTVFQILTGEDWNEVMYDGIRSYGNLGKSSMLSCLYYVILFICGNYILLNVFLAIAVDNLADTGSGNKEEKKEGENEEGEPTNVDGEEAKACNSSNVSPNIDEKTRFTDAERLIKSEEMNGDIADESMRKMSTRIDTEKENDEEYAEGDEEDEENGQTSAIRRVSEVMAKEKIKPIPNASSFFIFGPNNKFRKFCHFICNHPHFGNIVLVCIMVSSAMLAAEDPLDAESSRNRILNYFDYLFTSVFTVEITLKVITYGLVFHNGAFCRSSNNILDLLVVLTSIISYPINNDAISVVKILRVLRVLRPLRAINRAKGLKRVVQCVVVAVKSIGNIMLVTFLLEFMFAVIGVQLFNGKFQSCNDVSKNTHISCRGQYIYYNEADIAKVFVNKREWINNPLNFDNVPNAMLTLFAVSTFEGWPGVLYKSIDSFKEDYSGIYNNRPIVSIFYIAYIIVIAFFMINIFVGFVIVTFQQEGEEEYKNCELDKNQRKCIEFALKAKPVRRYIPKQSFRYRVWWLITSRPFEYIIFVLIMLNTISLALKFDKQPQRYEQVMDYLNMVFTGVFTVEFLLKLAAFGFKNYFSDAWNVFDFIIVLGSFIDIIYDHVNGTNNNHRGDRLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFVKSFQALPYVALLIVMLFFIYAVIGMQMFGKITTENEKEMKEINRNNNFQTFPQAILVLFRSATGEAWQNIMLHCLPDAMCDALSDQIRKEYYNLTVMRARQAGNLGFNDSMVIWPPHNFVKVKINKYISHYQDVAKCGSNFAYPYFISFYMICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPEAKGRIKHLDVVTLLRKINPPLGFGKYCPHRTACVTLVRMNMPLNSDGTVMFNATLFALVRTNLKIKTDGSTVDQLNEELRVVIKKIWKRTSQKMLDQVVPPAGNDDVTVGKFYATFLIQEWFRRWKQKRNEEQKGMAYSQSKRLSLMPFRTHGRGSGPLISLISPTLVTTNECDEKDKDYLPSHLGAERRTHSIFGTMMNVLQRVGSTRRDSNASPSTGSINHSTELPRDRSNSRPMILNQSKSPTNHPPVKLTLAPVIEGQVISNEEYSAEIPPKLPKTVSKQSLNYDKKPLTSKQPRVEYTMRDKLSLRSPPLDIDLPLLRSNVFPRPSRSQSSESPESIQRKEEK 1887 HSP 2 Score: 166.777 bits (421), Expect = 1.683e-40 Identity = 71/72 (98.61%), Postives = 71/72 (98.61%), Query Frame = 1
Query: 253 MTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPGQ 468
MTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPP Q
Sbjct: 1 MTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNTEYKCVENDYIESRYRFEPRTNYQLNYSPPAQ 72 The following BLAST results are available for this feature:
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Voltage-dependent L-type calcium channel subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30005127 ID=SMED30005127|Name=Voltage-dependent L-type calcium channel subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=9129bpback to top protein sequence of SMED30005127-orf-1 >SMED30005127-orf-1 ID=SMED30005127-orf-1|Name=SMED30005127-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2712bp MLNDRIYPNNMTGGRSGIDNCHPNQYSAPMHQYRQLFHTDQPFYDSHTRNback to top Annotated Terms
The following terms have been associated with this transcript:
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