Ast2 protein

Overview


Name	Ast2 protein (CCW36840.1)
Smed ID	SMED30005126
Length (bp)	882

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ast2 protein (SMED30005126) t-SNE clustered cells

Violin plots show distribution of expression levels for Ast2 protein (SMED30005126) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30005126

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
prepharyngeal region	SMED30005126	h1SMcG0009025	SmedASXL_009673	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30005126	h1SMcG0009025	SmedASXL_009673	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
prepharyngeal region	SMED30005126	h1SMcG0009025	SmedASXL_009674	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30005126	h1SMcG0009025	SmedASXL_009674	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
prepharyngeal region	SMED30005126	h1SMcG0009025	SmedASXL_009673	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30005126	h1SMcG0009025	SmedASXL_009673	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
prepharyngeal region	SMED30005126	h1SMcG0009025	SmedASXL_009674	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30005126	h1SMcG0009025	SmedASXL_009674	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
Smed sexual biotype	SMED30005126	h1SMcG0009037	Contig4486	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30005126	h1SMcG0009027	Contig4486	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30005126	h1SMcG0009025	Contig4486	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30005126	h1SMcG0009037	Contig4486	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30005126	h1SMcG0009027	Contig4486	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30005126	h1SMcG0009025	Contig4486	GPL15192	PMID:29674431 Fincher et al., 2018
head region	SMED30005126	h1SMcG0009025	OX_Smed_1.0.21359	ox_Smed_v2	PMID:24238224 Kao et al., 2013
head region	SMED30005126	h1SMcG0009025	OX_Smed_1.0.21359	ox_Smed_v2	PMID:24238224 Kao et al., 2013
neoblast	SMED30005126	h1SMcG0009025	SMED_01010_V2_1r	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30005126	h1SMcG0009027	SMED_01010_V2_1r	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30005126	h1SMcG0009025	SMED_01010_V2_1r	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30005126	h1SMcG0009027	SMED_01010_V2_1r	GPL14150	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of Ast2 protein vs. Ensembl Human
Match: ASTL (astacin like metalloendopeptidase [Source:HGNC Symbol;Acc:HGNC:31704])

HSP 1 Score: 81.6481 bits (200), Expect = 8.552e-17
Identity = 54/175 (30.86%), Postives = 85/175 (48.57%), Query Frame = 1

Query:  220 DIQIINGFKNHYANSKKWPNN-----IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF---QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMY-SKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFA 717
            DI   + F+   A S KWP        V +  +  + +   Q + ++L E ++    C++F   Q+ R+  +I +     GC+S +G +GG  Q ++L  P C+   +G + HE +H LGF H H R DRD +I + W+ IL      F K        PY+  SVMHY    F+
Sbjct:   77 DIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERS--TCIRFVTYQDQRD--FISII-PMYGCFSSVGRSGG-MQVVSLA-PTCLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSVMHYGRLAFS 244

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BLAST of Ast2 protein vs. Ensembl Human
Match: MEP1B (meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020])

HSP 1 Score: 74.7146 bits (182), Expect = 2.684e-14
Identity = 61/197 (30.96%), Postives = 92/197 (46.70%), Query Frame = 1

Query:  175 GLDNVKMGDMLLDSTDIQIINGFKNHYANSK-KWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQE-GRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFACNPSEKVVVKK 750
            GLD  + GD+ LD   I      +N     K +WP+ I  Y    +   +    +  +    +  L+ C+ F+      +YI V  K  GC+S +G      Q L++    C     T++HEF+HALGF H   R DRD+++ I WDRIL+ +   F        D    PY+  SVMHY+   F  N +E  +V +
Sbjct:   45 GLDLFE-GDIRLDRAQI------RNSIIGEKYRWPHTI-PYVLEDSLEMNAKGVILNAFERYR--LKTCIDFKPWAGETNYISV-FKGSGCWSSVGNRRVGKQELSI-GANCD-RIATVQHEFLHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKTAFQ-NGTEPTIVTR 227

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BLAST of Ast2 protein vs. Ensembl Human
Match: MEP1B (meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020])

HSP 1 Score: 74.3294 bits (181), Expect = 2.783e-14
Identity = 61/197 (30.96%), Postives = 92/197 (46.70%), Query Frame = 1

Query:  175 GLDNVKMGDMLLDSTDIQIINGFKNHYANSK-KWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQE-GRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFACNPSEKVVVKK 750
            GLD  + GD+ LD   I      +N     K +WP+ I  Y    +   +    +  +    +  L+ C+ F+      +YI V  K  GC+S +G      Q L++    C     T++HEF+HALGF H   R DRD+++ I WDRIL+ +   F        D    PY+  SVMHY+   F  N +E  +V +
Sbjct:   45 GLDLFE-GDIRLDRAQI------RNSIIGEKYRWPHTI-PYVLEDSLEMNAKGVILNAFERYR--LKTCIDFKPWAGETNYISV-FKGSGCWSSVGNRRVGKQELSI-GANCD-RIATVQHEFLHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKTAFQ-NGTEPTIVTR 227

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BLAST of Ast2 protein vs. Ensembl Human
Match: TLL2 (tolloid like 2 [Source:HGNC Symbol;Acc:HGNC:11844])

HSP 1 Score: 73.9442 bits (180), Expect = 4.198e-14
Identity = 48/153 (31.37%), Postives = 70/153 (45.75%), Query Frame = 1

Query:  271 WPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKRE-GCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFA 717
            WP  ++ Y   GNF   +    +Q++   +K    CV F E  +     V S R  GC S +G  GG  Q +++      +  G + HE  H +GF H H R DRD H+TI  + I   Q   F K +  E       Y+ +S+MHY    F+
Sbjct:  159 WPGGVIPYVIGGNFTGSQRAIFKQAMRHWEK--HTCVTFIERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKF--GIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFS 307

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BLAST of Ast2 protein vs. Ensembl Human
Match: MEP1A (meprin A subunit alpha [Source:HGNC Symbol;Acc:HGNC:7015])

HSP 1 Score: 73.9442 bits (180), Expect = 4.671e-14
Identity = 65/217 (29.95%), Postives = 105/217 (48.39%), Query Frame = 1

Query:  175 GLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQ--EGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDG---CEPDGPYETESVMHYNSEGF---ACNPSEKVVVKKNGGAIGYNHETTANDLQ 801
            GLD +  GD+LL  +     NG ++    + +W   I  Y  A N   +    +  +    +  L++CV F+  EG + + I    + +GC+S +G      Q +++   GC Y K  I+HE +HALGF H   R DRD+++ I WD+IL+     F   D     + + PY+ ES+MHY    F   A  P+    + +    IG   + +A DL+
Sbjct:   79 GLD-LFQGDILLQKSR----NGLRD---PNTRWTFPI-PYILADNLGLNAKGAILYAFEMFR--LKSCVDFKPYEGESSYII--FQQFDGCWSEVG-DQHVGQNISI-GQGCAY-KAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLE 279

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BLAST of Ast2 protein vs. Ensembl Celegans
Match: nas-4 (Zinc metalloproteinase nas-4 [Source:UniProtKB/Swiss-Prot;Acc:P55112])

HSP 1 Score: 101.293 bits (251), Expect = 9.834e-25
Identity = 66/206 (32.04%), Postives = 107/206 (51.94%), Query Frame = 1

Query:  178 LDNVKMGDMLLDSTDIQI-------INGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF---QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDG---CEPDGPYETESVMHYNSEGFACNPSEKVVVKKNG 756
            + N   GD+LL+S    +        N  K  Y   ++WPNN + YT +  +       +  ++ E     + CVKF      ++  Y+ ++   EGCYS++G TGG  QP++L++ GC+   GTI HE +HA+GF H   R+DRD++I + W  ++     QF K +       D PY+  S+MHY    F+ +  + +V KK+G
Sbjct:   69 IGNYSEGDILLESPKKFVEENNKLGRNAIKQIY---RRWPNNEIPYTLSSQYGSYARSVIANAMNEYHT--KTCVKFVARDPSKHHDYLWIHPD-EGCYSLVGKTGG-KQPVSLDS-GCI-QVGTIVHELMHAVGFFHEQSRQDRDSYIDVVWQNVMNGADDQFEKYNLNVISHLDEPYDYASIMHYGPYAFSGSGKKTLVPKKSG 265

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BLAST of Ast2 protein vs. Ensembl Celegans
Match: nas-4 (Zinc metalloproteinase nas-4 [Source:UniProtKB/Swiss-Prot;Acc:P55112])

HSP 1 Score: 100.523 bits (249), Expect = 3.020e-24
Identity = 66/207 (31.88%), Postives = 107/207 (51.69%), Query Frame = 1

Query:  178 LDNVKMGDMLLDSTDIQI-------INGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF---QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDG---CEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGG 759
            + N   GD+LL+S    +        N  K  Y   ++WPNN + YT +  +       +  ++ E     + CVKF      ++  Y+ ++   EGCYS++G TGG  QP++L++ GC+   GTI HE +HA+GF H   R+DRD++I + W  ++     QF K +       D PY+  S+MHY    F+ +  + +V KK+G 
Sbjct:   69 IGNYSEGDILLESPKKFVEENNKLGRNAIKQIY---RRWPNNEIPYTLSSQYGSYARSVIANAMNEYHT--KTCVKFVARDPSKHHDYLWIHPD-EGCYSLVGKTGG-KQPVSLDS-GCI-QVGTIVHELMHAVGFFHEQSRQDRDSYIDVVWQNVMNGADDQFEKYNLNVISHLDEPYDYASIMHYGPYAFSGSGKKTLVPKKSGS 266

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BLAST of Ast2 protein vs. Ensembl Celegans
Match: nas-4 (Zinc metalloproteinase nas-4 [Source:UniProtKB/Swiss-Prot;Acc:P55112])

HSP 1 Score: 100.908 bits (250), Expect = 3.453e-24
Identity = 66/207 (31.88%), Postives = 107/207 (51.69%), Query Frame = 1

Query:  178 LDNVKMGDMLLDSTDIQI-------INGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF---QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDG---CEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGG 759
            + N   GD+LL+S    +        N  K  Y   ++WPNN + YT +  +       +  ++ E     + CVKF      ++  Y+ ++   EGCYS++G TGG  QP++L++ GC+   GTI HE +HA+GF H   R+DRD++I + W  ++     QF K +       D PY+  S+MHY    F+ +  + +V KK+G 
Sbjct:   69 IGNYSEGDILLESPKKFVEENNKLGRNAIKQIY---RRWPNNEIPYTLSSQYGSYARSVIANAMNEYHT--KTCVKFVARDPSKHHDYLWIHPD-EGCYSLVGKTGG-KQPVSLDS-GCI-QVGTIVHELMHAVGFFHEQSRQDRDSYIDVVWQNVMNGADDQFEKYNLNVISHLDEPYDYASIMHYGPYAFSGSGKKTLVPKKSGS 266

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BLAST of Ast2 protein vs. Ensembl Celegans
Match: nas-6 (Zinc metalloproteinase nas-6 [Source:UniProtKB/Swiss-Prot;Acc:Q9U3S9])

HSP 1 Score: 91.6633 bits (226), Expect = 5.239e-21
Identity = 60/180 (33.33%), Postives = 90/180 (50.00%), Query Frame = 1

Query:  229 IINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVN-SKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGP---YETESVMHYNSEGFACNPSEKVVVKKNG 756
            + N  KN       W   ++ Y     F  ++I+ + ++    ++    C++F E R G    +N  K  GCYS +G TGG  Q ++L   GC + +  I HE +H++GF H H R DRD+HI I WD IL    SQF K      D     Y+ +S+MHY+S  F+ N    +   +NG
Sbjct:   70 LFNALKN---KQLTWEGGVIPYEMDTAFSPNEIKILEKAFDSYRR--TTCIRF-EKREGQTDYLNIVKGYGCYSQVGRTGG-KQEISLGR-GCFFHE-IIVHELMHSVGFWHEHSRADRDDHIKINWDNILPGMKSQFDKISAVLQDLQGENYDYKSIMHYDSTAFSRNGRNTIETVENG 240

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BLAST of Ast2 protein vs. Ensembl Celegans
Match: nas-15 (Zinc metalloproteinase nas-15 [Source:UniProtKB/Swiss-Prot;Acc:P55115])

HSP 1 Score: 91.6633 bits (226), Expect = 1.525e-20
Identity = 65/190 (34.21%), Postives = 96/190 (50.53%), Query Frame = 1

Query:  214 STDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF--QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKC--DGCEPDGP-YETESVMHYNSEGFACNPSEKVVVKKNGGAIG 768
            S D +  N  KN     + WP   + YT +  +       +  S+ E       C+++  +E  + +Y+ +   R GCYSM+G  GG  Q L+L + GC+  KG I HE +HA+GF H   R DRD+HITI W+ I      QF K      +  G  Y+  S+MHY ++ F+ N    ++ KKNG  IG
Sbjct:  107 SEDGKWYNAIKNRL---QLWPEGRIPYTISSQYSSYSRSLIAASMQEYAS--HTCIRWVPKEAADVNYVHIYPDR-GCYSMVGKMGG-KQSLSLGS-GCI-QKGIILHELMHAVGFFHEQSRTDRDDHITIMWNNIQAGMQGQFEKYGHGTIQSLGTGYDYGSIMHYGTKAFSRNGQPTMIPKKNGATIG 287

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BLAST of Ast2 protein vs. Ensembl Fly
Match: CG6763 (gene:FBgn0039069 transcript:FBtr0084378)

HSP 1 Score: 129.798 bits (325), Expect = 7.170e-35
Identity = 66/191 (34.55%), Postives = 104/191 (54.45%), Query Frame = 1

Query:  196 GDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF-QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG-PYETESVMHYNSEGFACNPSEKVVVKKNGGA 762
            GDML+  TD+ + NG       S +WPN +V Y   GNF    + T+  ++GE  +  + C++F +      YI +     GC+S +G  GG  Q +NL++PGC+   GT  HE +HALGF+H   R +RD ++ I+++ + +S  + F K    E  G PY+  SVMHY+   F+ N    ++  +  GA
Sbjct:   95 GDMLVPQTDLIMKNGLPTQ---SSRWPNGVVPYEIRGNFNARDMATIENAIGEYHR--RTCIRFVKRSSERDYISIRGDNSGCWSSVGRVGG-KQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFEKAARTEAFGVPYDYGSVMHYSKNAFSINGQPTILAMQANGA 279

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BLAST of Ast2 protein vs. Ensembl Fly
Match: CG6763 (gene:FBgn0039069 transcript:FBtr0334497)

HSP 1 Score: 129.798 bits (325), Expect = 7.170e-35
Identity = 66/191 (34.55%), Postives = 104/191 (54.45%), Query Frame = 1

Query:  196 GDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF-QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG-PYETESVMHYNSEGFACNPSEKVVVKKNGGA 762
            GDML+  TD+ + NG       S +WPN +V Y   GNF    + T+  ++GE  +  + C++F +      YI +     GC+S +G  GG  Q +NL++PGC+   GT  HE +HALGF+H   R +RD ++ I+++ + +S  + F K    E  G PY+  SVMHY+   F+ N    ++  +  GA
Sbjct:   95 GDMLVPQTDLIMKNGLPTQ---SSRWPNGVVPYEIRGNFNARDMATIENAIGEYHR--RTCIRFVKRSSERDYISIRGDNSGCWSSVGRVGG-KQEVNLQSPGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFEKAARTEAFGVPYDYGSVMHYSKNAFSINGQPTILAMQANGA 279

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BLAST of Ast2 protein vs. Ensembl Fly
Match: CG11865 (gene:FBgn0028947 transcript:FBtr0080753)

HSP 1 Score: 95.5153 bits (236), Expect = 4.879e-23
Identity = 71/248 (28.63%), Postives = 114/248 (45.97%), Query Frame = 1

Query:  100 LGFVVIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQ---------IINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQ--EGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQF--TKCDGCEPDG-PYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQ 801
            L   VI +  G     R S+KL+          D++L S  +Q         ++  +  +Y     W    + Y++AG F    I ++  ++ E+    + CVKF+  E +    + +  +  GC+S +G  G   Q LNL   GCM S  TI+HE +HALGF HTH    RD ++ I+ D I +     F   + +G    G  Y+ +S+MHY    F+ N    +V  K+   IG   + +  D+Q
Sbjct:    4 LALAVI-FGLGSSANGRPSIKLQE--------DDIILISEQLQYFEGNLEGRVVKSWSEYY-----WKGRTLVYSYAGGFSSLDIASIESAMAEISS--KTCVKFRRTEYKREPQVVIQKEGSGCWSYVGYLGRADQTLNL-GSGCM-SNRTIQHELLHALGFFHTHSDPQRDKYVRIQTDNIRSGHEHNFQRLRANGVTNYGFGYDYDSIMHYGPFAFSKNGQSTIVPLKSHAKIGQATQMSPKDVQ 233

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BLAST of Ast2 protein vs. Ensembl Fly
Match: CG15255 (gene:FBgn0028950 transcript:FBtr0080785)

HSP 1 Score: 93.2041 bits (230), Expect = 5.491e-22
Identity = 60/197 (30.46%), Postives = 96/197 (48.73%), Query Frame = 1

Query:  235 NGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEG--RNGHYIEVNSKREGCYSMLGVTGGPSQPLNLE----NPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTK-CDGCEPDGP--YETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDL 798
            NG  N     K+WP N+V Y  + +F     + ++  +  L+  L  C++F+E    +  Y+ V +K  GCY+ +G  G P Q +NLE      GC +  GTI HEF+HALGF H      RD+ I + ++ I+  +   F K  D    D    Y+ +S +HY    F+ N  + +V   +   IG     ++ D+
Sbjct:   59 NGLIN---TEKRWPGNVVVYRISDDFDTAHKKAIQTGIDTLE--LHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQGAP-QEMNLEIYPLGEGC-FRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSINGEDTIVPLDSSAVIGQRVGLSSKDI 248

[Close]

BLAST of Ast2 protein vs. Ensembl Fly
Match: CG15255 (gene:FBgn0028950 transcript:FBtr0343719)

HSP 1 Score: 93.2041 bits (230), Expect = 5.491e-22
Identity = 60/197 (30.46%), Postives = 96/197 (48.73%), Query Frame = 1

Query:  235 NGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEG--RNGHYIEVNSKREGCYSMLGVTGGPSQPLNLE----NPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTK-CDGCEPDGP--YETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDL 798
            NG  N     K+WP N+V Y  + +F     + ++  +  L+  L  C++F+E    +  Y+ V +K  GCY+ +G  G P Q +NLE      GC +  GTI HEF+HALGF H      RD+ I + ++ I+  +   F K  D    D    Y+ +S +HY    F+ N  + +V   +   IG     ++ D+
Sbjct:   59 NGLIN---TEKRWPGNVVVYRISDDFDTAHKKAIQTGIDTLE--LHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQGAP-QEMNLEIYPLGEGC-FRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSINGEDTIVPLDSSAVIGQRVGLSSKDI 248

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BLAST of Ast2 protein vs. Ensembl Zebrafish
Match: c6ast3 (six-cysteine containing astacin protease 3 [Source:ZFIN;Acc:ZDB-GENE-050320-99])

HSP 1 Score: 100.138 bits (248), Expect = 1.674e-24
Identity = 57/173 (32.95%), Postives = 88/173 (50.87%), Query Frame = 1

Query:  286 VTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF-QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVV-VKKNGGAIGYNHETTANDL 798
            V Y  A ++   +++ +++ L         C++F   G    YI + S R GCYS +G   G +Q ++L   GC+Y   T++HE +HALGF H   R DRDNHI + W+ IL      F K +      PY+  SVM Y    F+ N    ++ +  N  A+G + E + ND+
Sbjct:   79 VPYVIANHYSSRELEIIQRGLDSFS--YSTCIRFFPRGNERDYISIES-RSGCYSYVG-RQGYAQTVSLARSGCLY-HSTVQHELLHALGFNHEQTRNDRDNHIQVIWENILDDMKYNFNKINTLNQGTPYDYSSVMQYERYAFSKNGLPTMIPIPNNNAALGTSTEMSQNDI 246

[Close]

Query:  286 VTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF-QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVV-VKKNGGAIGYNHETTANDL 798
            V Y  A ++   +++ +++ L         C++F   G    YI + S R GCYS +G   G +Q ++L   GC+Y   T++HE +HALGF H   R DRDNHI + W+ IL      F K +      PY+  SVM Y    F+ N    ++ +  N  A+G + E + ND+
Sbjct:   79 VPYVIANHYSSRELEIIQRGLDSFS--YSTCIRFFPRGNERDYISIES-RSGCYSYVG-RQGYAQTVSLARSGCLY-HSTVQHELLHALGFNHEQTRNDRDNHIQVIWENILDDMKYNFNKINTLNQGTPYDYSSVMQYERYAFSKNGLPTMIPIPNNNAALGTSTEMSQNDI 246

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BLAST of Ast2 protein vs. Ensembl Zebrafish
Match: hce2l1 (high choriolytic enzyme 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-070912-147])

HSP 1 Score: 95.9005 bits (237), Expect = 2.472e-23
Identity = 54/170 (31.76%), Postives = 88/170 (51.76%), Query Frame = 1

Query:  256 ANSKKWPNNIVTYTFAGNFPQ---DKIQTVRQSLGELQKDLQNCVKF-QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKN 753
             +S +WP  +  + +         D +  +    G L      CVKF       +++ +   R GC+S LG+TGG SQ ++L++PGCM+S G   HE +HALGF+H   R DRD +++I W+ I+ +Q   F K +    +  Y+  SVMHY    F+ +    ++ K +
Sbjct:   24 GDSCRWPKAVDGFVYVPYIMSTLYDDMDRITIETGMLDISSSTCVKFVPRTHQANFLNIQ-PRYGCWSYLGMTGG-SQTVSLQSPGCMWS-GVASHELMHALGFVHEQSRSDRDRYVSILWENIIENQRHNFRKYETNNLNTAYDYSSVMHYGRYAFSEDGGPTIIPKPD 190

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BLAST of Ast2 protein vs. Ensembl Zebrafish
Match: c6ast4 (six-cysteine containing astacin protease 4 [Source:ZFIN;Acc:ZDB-GENE-050626-100])

HSP 1 Score: 96.6709 bits (239), Expect = 3.883e-23
Identity = 55/173 (31.79%), Postives = 88/173 (50.87%), Query Frame = 1

Query:  286 VTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVV-VKKNGGAIGYNHETTANDL 798
            V Y  A ++   +++ +++ L        +C++F    N   YI + S R GCYS +G  G   Q ++L   GC+Y   T++HE +HALGF H   R DRDNHI + W+ IL      F K +      PY+ +SVM Y    F+ N    ++ +  N   +G + + + ND+
Sbjct:   89 VPYVIANHYSSRELEIIQRGLDSFAS--VSCIRFFRRSNERDYISIES-RSGCYSYVGRQGN-VQTVSLARSGCLY-HSTVQHELLHALGFNHEQTRSDRDNHIQVIWENILDDMKYNFNKINTLNQGTPYDYKSVMQYERYAFSKNGYPTMIPIPNNNAELGKSTQMSQNDI 256

[Close]

Query:  286 VTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVV-VKKNGGAIGYNHETTANDL 798
            V Y  A ++   +++ +++ L        +C++F    N   YI + S R GCYS +G  G   Q ++L   GC+Y   T++HE +HALGF H   R DRDNHI + W+ IL      F K +      PY+ +SVM Y    F+ N    ++ +  N   +G + + + ND+
Sbjct:   89 VPYVIANHYSSRELEIIQRGLDSFAS--VSCIRFFRRSNERDYISIES-RSGCYSYVGRQGN-VQTVSLARSGCLY-HSTVQHELLHALGFNHEQTRSDRDNHIQVIWENILDDMKYNFNKINTLNQGTPYDYKSVMQYERYAFSKNGYPTMIPIPNNNAELGKSTQMSQNDI 256

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BLAST of Ast2 protein vs. Ensembl Xenopus
Match: kpna4 (karyopherin alpha 4 (importin alpha 3) [Source:Xenbase;Acc:XB-GENE-1011058])

HSP 1 Score: 95.5153 bits (236), Expect = 1.627e-21
Identity = 63/196 (32.14%), Postives = 103/196 (52.55%), Query Frame = 1

Query:  196 GDMLLDSTDIQIINGFKNHYANSKKWPNN-----IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF-QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAI 765
            G+M L      +IN  ++  ++   WP +     +V Y F+ N+  D++   + ++ E +     CV+F  +     ++ + S   GC SM+G  GG  Q + L + GCM S+G I+HE  HALGF H HMR DRD+++TI  + I+ S  + F+K         Y+  SVMHY+   F+ +P +  +V K   +I
Sbjct:   49 GNMALTEGGDILINIGRSATSSDYLWPKSADGTVVVPYIFSYNYSADELTLFKTAMQEFET--LTCVRFVPKTIQRDFLNIVSNG-GCLSMVGRNGG-GQKVELASYGCM-SRGVIQHELNHALGFYHEHMRSDRDDYVTIITENIIPSYENYFSKRKTNNMGIIYDYNSVMHYSRNTFSISPDKSTIVPKPDPSI 239

[Close]

BLAST of Ast2 protein vs. Ensembl Xenopus
Match: polr2l.2 (polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa, gene 2 [Source:Xenbase;Acc:XB-GENE-5898446])

HSP 1 Score: 91.2781 bits (225), Expect = 3.836e-20
Identity = 59/172 (34.30%), Postives = 86/172 (50.00%), Query Frame = 1

Query:  220 DIQIINGFKNHYANSKKWPNNI-----VTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQE-GRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFA 717
            DI I  G       S  WP +      V Y  + ++  ++  ++R +L  L+ +   CV F E      ++++ S   GC+S +G TGG +Q L+L + GC+ +KG I+HE  HALGF H   R DRD +I + W  I  S    F   D    D PY+  SVMHY    F+
Sbjct:   54 DIAIETGRSATKCPSCLWPKSADGTVRVPYRLSADYSDNEKSSIRDAL--LEFNTLTCVHFVERSTEEDFLDIVSD-SGCWSSIGRTGG-AQTLSLMSSGCL-AKGIIQHEVDHALGFYHEQSRSDRDTYIDVLWQYICESDWGSFEMVDTDNLDLPYDYSSVMHYGWYAFS 220

[Close]

BLAST of Ast2 protein vs. Ensembl Xenopus
Match: ENSXETT00000022029.1 (astacin-like metalloendopeptidase [Source:NCBI gene;Acc:100496745])

HSP 1 Score: 91.2781 bits (225), Expect = 4.129e-20
Identity = 54/166 (32.53%), Postives = 85/166 (51.20%), Query Frame = 1

Query:  271 WPNN-----IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRN-GHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKK 750
            WP +     +V YT + N+   +   +R ++ E+   +  C++F    N   Y+ +    +GC+S +G  GG +Q ++L   GC++  G I+HE +H+LGF H   R DRDN+I I WD I   +   F K +      PY+  SVMHY    FA N  +  +  K
Sbjct:   24 WPRSRKGLVLVPYTLSNNYNSTERDIIRAAMDEVT--VLTCIQFVTYNNESDYLRIR-PYDGCWSYIGRVGG-AQDVSLMKTGCLH-HGVIQHELLHSLGFQHEQCRSDRDNYININWDNISHDKERNFLKMNTQNLGSPYDYLSVMHYGKFAFATNSGKPTLEPK 184

[Close]

BLAST of Ast2 protein vs. Ensembl Xenopus
Match: ENSXETT00000032332.1 (astacin-like metallo-endopeptidase 3 gene b1 [Source:NCBI gene;Acc:100498420])

HSP 1 Score: 90.8929 bits (224), Expect = 6.679e-20
Identity = 55/166 (33.13%), Postives = 83/166 (50.00%), Query Frame = 1

Query:  271 WPNN-----IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKN 753
            WP +     IV Y F+ N+  D++   + ++ E +     CV+F    N           GC S LG  GG  Q + L++ GC+Y +G I+HE  HALGF H   R DRD+++TI  + I+      F K D       Y+  SVMHY+ + F+ N +  +V K +
Sbjct:   51 WPKSTDGTVIVPYNFSSNYSADQLALFKSTMQEYES--LTCVRFVPRANETDFLSIVSDNGCASFLGKVGG-DQTVQLDSYGCIY-RGIIQHELNHALGFYHEQSRSDRDDYVTIHTENIIPGYEGNFNKADSNNLGLEYDYSSVMHYSGDAFSKNGNLTIVPKPD 212

[Close]

BLAST of Ast2 protein vs. Ensembl Xenopus
Match: ENSXETT00000032191.1 (astacin-like metallo-endopeptidase 3 gene b1 [Source:NCBI gene;Acc:100498420])

HSP 1 Score: 90.5077 bits (223), Expect = 9.959e-20
Identity = 55/166 (33.13%), Postives = 83/166 (50.00%), Query Frame = 1

Query:  271 WPNN-----IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKN 753
            WP +     IV Y F+ N+  D++   + ++ E +     CV+F    N           GC S LG  GG  Q + L++ GC+Y +G I+HE  HALGF H   R DRD+++TI  + I+      F K D       Y+  SVMHY+ + F+ N +  +V K +
Sbjct:  124 WPKSTDGTVIVPYNFSSNYSADQLALFKSTMQEYES--LTCVRFVPRANETDFLSIVSDNGCASFLGKVGG-DQTVQLDSYGCIY-RGIIQHELNHALGFYHEQSRSDRDDYVTIHTENIIPGYEGNFNKADSNNLGLEYDYSSVMHYSGDAFSKNGNLTIVPKPD 285

[Close]

BLAST of Ast2 protein vs. Ensembl Mouse
Match: Mep1a (meprin 1 alpha [Source:MGI Symbol;Acc:MGI:96963])

HSP 1 Score: 78.1814 bits (191), Expect = 1.124e-15
Identity = 62/194 (31.96%), Postives = 94/194 (48.45%), Query Frame = 1

Query:  184 NVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQ--EGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDG---CEPDGPYETESVMHYNSEGFACNPSEKVVVKK 750
            N+  GD+LL  T     N  ++    S +W   I  Y  A N   +    +  +    +  L++CV F+  EG + + I    K  GC+SM+G      Q +++   GC + K TI+HE +HALGF H   R DRD+++ I WD+I+T     F   D     + + PY+ ES+MHY    F  N S   +  K
Sbjct:   65 NLFQGDILLPRTR----NAMRD---PSSRWKLPI-PYILADNLELNAKGAILHAFEMFR--LKSCVDFKPYEGESSYII--FQKLSGCWSMIG-DQQVGQNISI-GEGCDF-KATIEHEILHALGFFHEQSRTDRDDYVNIWWDQIITDYEHNFNTYDDNTITDLNTPYDYESLMHYGPFSFNKNESIPTITTK 243

[Close]

BLAST of Ast2 protein vs. Ensembl Mouse
Match: Mep1a (meprin 1 alpha [Source:MGI Symbol;Acc:MGI:96963])

HSP 1 Score: 78.1814 bits (191), Expect = 1.203e-15
Identity = 62/194 (31.96%), Postives = 94/194 (48.45%), Query Frame = 1

Query:  184 NVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQ--EGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDG---CEPDGPYETESVMHYNSEGFACNPSEKVVVKK 750
            N+  GD+LL  T     N  ++    S +W   I  Y  A N   +    +  +    +  L++CV F+  EG + + I    K  GC+SM+G      Q +++   GC + K TI+HE +HALGF H   R DRD+++ I WD+I+T     F   D     + + PY+ ES+MHY    F  N S   +  K
Sbjct:   52 NLFQGDILLPRTR----NAMRD---PSSRWKLPI-PYILADNLELNAKGAILHAFEMFR--LKSCVDFKPYEGESSYII--FQKLSGCWSMIG-DQQVGQNISI-GEGCDF-KATIEHEILHALGFFHEQSRTDRDDYVNIWWDQIITDYEHNFNTYDDNTITDLNTPYDYESLMHYGPFSFNKNESIPTITTK 230

[Close]

BLAST of Ast2 protein vs. Ensembl Mouse
Match: Mep1b (meprin 1 beta [Source:MGI Symbol;Acc:MGI:96964])

HSP 1 Score: 76.2554 bits (186), Expect = 5.286e-15
Identity = 59/196 (30.10%), Postives = 93/196 (47.45%), Query Frame = 1

Query:  175 GLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGR-NGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFACNPSEKVVVKK 750
            GLD  + GD+ L++      NG  +   + K+WP+ I  Y    +   +    +  +    +  L+ C+ F+      +YI V  K  GC+S +G      Q L++    C     T++HEF+HALGF H   R DRD+++ I WDRI   +   F   +    D    PY+  SVMHY+   F  N +E  +V +
Sbjct:   47 GLDLFE-GDIKLEA------NGKNSIIGDHKRWPHTI-PYVLEDSLEMNAKGVILNAFERYR--LKTCIDFKPWSGEANYISV-FKGSGCWSSVGNIHAGKQELSI-GTNCD-RIATVQHEFLHALGFWHEQSRADRDDYVIIVWDRIQPGKEHNFNIYNDSVSDSLNVPYDYTSVMHYSKTAFQ-NGTESTIVTR 228

[Close]

BLAST of Ast2 protein vs. Ensembl Mouse
Match: Tll2 (tolloid-like 2 [Source:MGI Symbol;Acc:MGI:1346044])

HSP 1 Score: 74.3294 bits (181), Expect = 2.307e-14
Identity = 55/202 (27.23%), Postives = 85/202 (42.08%), Query Frame = 1

Query:  124 ANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKRE-GCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFA 717
            +N     PR+  K  T  L N    +    +   ++     +     + WP  ++ Y   GNF   +    +Q++   +K    CV F E  +     V S R  GC S +G  GG  Q +++      +  G + HE  H +GF H H R DRD H+TI  + I   Q   F K +  E       Y+ +S+MHY    F+
Sbjct:  109 SNASIQAPRKDGKDATTFLPNPGTSNTTAKTFSARVRRATTSR--TERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEK--HTCVTFVERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKF--GIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFS 304

[Close]

BLAST of Ast2 protein vs. Ensembl Mouse
Match: Tll2 (tolloid-like 2 [Source:MGI Symbol;Acc:MGI:1346044])

HSP 1 Score: 74.3294 bits (181), Expect = 2.615e-14
Identity = 55/202 (27.23%), Postives = 85/202 (42.08%), Query Frame = 1

Query:  124 ANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKRE-GCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFA 717
            +N     PR+  K  T  L N    +    +   ++     +     + WP  ++ Y   GNF   +    +Q++   +K    CV F E  +     V S R  GC S +G  GG  Q +++      +  G + HE  H +GF H H R DRD H+TI  + I   Q   F K +  E       Y+ +S+MHY    F+
Sbjct:  109 SNASIQAPRKDGKDATTFLPNPGTSNTTAKTFSARVRRATTSR--TERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEK--HTCVTFVERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKF--GIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFS 304

[Close]

BLAST of Ast2 protein vs. UniProt/SwissProt
Match: sp|P55112|NAS4_CAEEL (Zinc metalloproteinase nas-4 OS=Caenorhabditis elegans OX=6239 GN=nas-4 PE=2 SV=4)

HSP 1 Score: 101.293 bits (251), Expect = 1.251e-23
Identity = 66/206 (32.04%), Postives = 107/206 (51.94%), Query Frame = 1

Query:  178 LDNVKMGDMLLDSTDIQI-------INGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF---QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDG---CEPDGPYETESVMHYNSEGFACNPSEKVVVKKNG 756
            + N   GD+LL+S    +        N  K  Y   ++WPNN + YT +  +       +  ++ E     + CVKF      ++  Y+ ++   EGCYS++G TGG  QP++L++ GC+   GTI HE +HA+GF H   R+DRD++I + W  ++     QF K +       D PY+  S+MHY    F+ +  + +V KK+G
Sbjct:   69 IGNYSEGDILLESPKKFVEENNKLGRNAIKQIY---RRWPNNEIPYTLSSQYGSYARSVIANAMNEYHT--KTCVKFVARDPSKHHDYLWIHPD-EGCYSLVGKTGG-KQPVSLDS-GCI-QVGTIVHELMHAVGFFHEQSRQDRDSYIDVVWQNVMNGADDQFEKYNLNVISHLDEPYDYASIMHYGPYAFSGSGKKTLVPKKSG 265

[Close]

BLAST of Ast2 protein vs. UniProt/SwissProt
Match: sp|P31581|HCE2_ORYLA (High choriolytic enzyme 2 OS=Oryzias latipes OX=8090 GN=hceb PE=2 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 5.790e-22
Identity = 52/146 (35.62%), Postives = 79/146 (54.11%), Query Frame = 1

Query:  283 IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFA 717
            ++ Y  +  + + ++ T+  ++       + C++F    N + +I V SK  GCYS LG  GG  Q L+L   GCMYS G I+HE  HALGF H   R DRD+++ I W  I+ +    F K D    + PY+  S+MHY  + F+
Sbjct:  100 VIPYVISSQYSRGEVATIEGAMRAFNG--RTCIRFVRRTNEYDFISVVSK-NGCYSELGRKGG-QQELSLNRGGCMYS-GIIQHELNHALGFQHEQTRSDRDSYVRINWQNIIPASAYNFNKHDTNNLNTPYDYSSIMHYGRDAFS 240

[Close]

BLAST of Ast2 protein vs. UniProt/SwissProt
Match: sp|P31579|LCE_ORYLA (Low choriolytic enzyme OS=Oryzias latipes OX=8090 GN=lce PE=1 SV=1)

HSP 1 Score: 95.1301 bits (235), Expect = 1.260e-21
Identity = 67/220 (30.45%), Postives = 101/220 (45.91%), Query Frame = 1

Query:  160 KLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYA-NSKKWP---NNIVT--YTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKN-GGAIGYNHETTANDL 798
            ++    ++ +  GD++L  T     N  K   A +S +WP   N IV   Y  + N+  D+ +T+R ++ E  +  + C+ F    N         R GC SM+G  G   Q + L+  GC+     I+HE +HALGF H H R DRD H+ I W+ I+      F K D      PY+  S+MHY    F  +  E +    N   AIG     +  D+
Sbjct:   51 RMNNNSMEELLEGDLVLPKTR----NAMKCFGAPDSCRWPKSSNGIVKVPYVVSDNYESDEKETIRNAMKEFAE--KTCIHFVPRNNERAYLSLEPRFGCKSMMGYVGD-KQVVVLQRFGCI-KHAVIQHELLHALGFYHEHTRSDRDQHVKINWENIIKDFTHNFDKNDTDNLGTPYDYGSIMHYGRTAFGKDRKETITPIPNPKAAIGQTERMSDIDI 262

[Close]

BLAST of Ast2 protein vs. UniProt/SwissProt
Match: sp|P31580|HCE1_ORYLA (High choriolytic enzyme 1 OS=Oryzias latipes OX=8090 GN=hcea PE=1 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 2.021e-21
Identity = 51/146 (34.93%), Postives = 79/146 (54.11%), Query Frame = 1

Query:  283 IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFA 717
            ++ Y  +  +   ++ T+  ++       + C++F    N + +I V SK  GCYS LG  GG  Q L++   GCMYS G I+HE  HALGF H   R DRD+++ I W+ I+ +    F K D    + PY+  S+MHY  + F+
Sbjct:   91 VIPYVISSEYSGGEVATIEGAMRAFNG--KTCIRFVRRTNEYDFISVVSK-TGCYSELGRKGG-QQELSINRGGCMYS-GIIQHELNHALGFQHEQTRSDRDSYVRINWENIIPASAYNFNKHDTNNLNTPYDYSSIMHYGRDAFS 231

[Close]

BLAST of Ast2 protein vs. UniProt/SwissProt
Match: sp|Q9U3S9|NAS6_CAEEL (Zinc metalloproteinase nas-6 OS=Caenorhabditis elegans OX=6239 GN=nas-6 PE=2 SV=2)

HSP 1 Score: 91.6633 bits (226), Expect = 6.664e-20
Identity = 60/180 (33.33%), Postives = 90/180 (50.00%), Query Frame = 1

Query:  229 IINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVN-SKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGP---YETESVMHYNSEGFACNPSEKVVVKKNG 756
            + N  KN       W   ++ Y     F  ++I+ + ++    ++    C++F E R G    +N  K  GCYS +G TGG  Q ++L   GC + +  I HE +H++GF H H R DRD+HI I WD IL    SQF K      D     Y+ +S+MHY+S  F+ N    +   +NG
Sbjct:   70 LFNALKN---KQLTWEGGVIPYEMDTAFSPNEIKILEKAFDSYRR--TTCIRF-EKREGQTDYLNIVKGYGCYSQVGRTGG-KQEISLGR-GCFFHE-IIVHELMHSVGFWHEHSRADRDDHIKINWDNILPGMKSQFDKISAVLQDLQGENYDYKSIMHYDSTAFSRNGRNTIETVENG 240

[Close]

BLAST of Ast2 protein vs. TrEMBL
Match: A0A060Q714 (Metalloendopeptidase OS=Schmidtea mediterranea OX=79327 GN=Ast2 PE=2 SV=1)

HSP 1 Score: 513.457 bits (1321), Expect = 0.000e+0
Identity = 243/243 (100.00%), Postives = 243/243 (100.00%), Query Frame = 1

Query:   76 MEKLILLLLGFVVIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            MEKLILLLLGFVVIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM
Sbjct:    1 MEKLILLLLGFVVIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 243

[Close]

BLAST of Ast2 protein vs. TrEMBL
Match: A0A060Q785 (Metalloendopeptidase OS=Schmidtea mediterranea OX=79327 GN=Ast1 PE=2 SV=1)

HSP 1 Score: 399.438 bits (1025), Expect = 3.925e-138
Identity = 186/244 (76.23%), Postives = 208/244 (85.25%), Query Frame = 1

Query:   76 MEKLILLLLGFVVIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGG-PSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            M+K+ L+ L   VI Y +GQCGCPRQ  KL  R +D++KMGDMLLD +DI +INGFKNHYAN+KKWPNN V Y+FAGNFP+DKI  VRQ LGELQ+DL NCVKF E   GHYIEVNSK+EGCYS+LG   G P+QPLNLENPGCMYSKGT+KHEFIHALGFMHTHMRKDRDNHITI W RI TSQCSQFTKCDGCE DGPYET SVMHYNSEGFAC+P EKVV++K+GGAIGYNH+TT NDL M
Sbjct:    1 MQKMFLMCLAIAVIGYVSGQCGCPRQ--KLLKRSVDSMKMGDMLLDKSDIALINGFKNHYANTKKWPNNNVVYSFAGNFPRDKIPVVRQCLGELQRDLGNCVKFTESNQGHYIEVNSKQEGCYSLLGYAAGMPTQPLNLENPGCMYSKGTVKHEFIHALGFMHTHMRKDRDNHITINWARIETSQCSQFTKCDGCELDGPYETTSVMHYNSEGFACDPREKVVLRKDGGAIGYNHDTTPNDLNM 242

[Close]

BLAST of Ast2 protein vs. TrEMBL
Match: A0A060Q786 (Metalloendopeptidase OS=Schmidtea mediterranea OX=79327 GN=Ast6 PE=2 SV=1)

HSP 1 Score: 358.992 bits (920), Expect = 3.991e-122
Identity = 167/243 (68.72%), Postives = 192/243 (79.01%), Query Frame = 1

Query:   76 MEKLILLLLGFVVIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            M  L  LLL    + Y +GQCGCPRQ  KL  RGLD+++MGDM+LD +DI +INGFK HY+N+K+WPNN V ++FA  FP DK   VR+ L ELQKDL NCVKF E    HYIEV+S  +GCYS+LG TGGP+QPLNL+NPGCMYSKGT+KHEFIHALGFMHTHMRKDRDNHITIKWDRILTS CSQF KC+GC+ DGPYET SVMHY S GFAC P E VV K++GG I YNH T+ NDL M
Sbjct:    1 MRSLFCLLLIVAAVSYVSGQCGCPRQ--KLLKRGLDSMQMGDMVLDKSDIALINGFKAHYSNTKRWPNNQVLFSFAPAFPGDKKGIVRECLVELQKDLGNCVKFSESTASHYIEVHSLNQGCYSLLGYTGGPNQPLNLQNPGCMYSKGTVKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSHCSQFVKCEGCDLDGPYETNSVMHYPSYGFACVPGENVVFKRDGGLIDYNHVTSRNDLDM 241

[Close]

BLAST of Ast2 protein vs. TrEMBL
Match: I1ZIC3 (Metalloendopeptidase OS=Schmidtea mediterranea OX=79327 GN=Ast3 PE=2 SV=1)

HSP 1 Score: 272.707 bits (696), Expect = 4.618e-88
Identity = 130/243 (53.50%), Postives = 166/243 (68.31%), Query Frame = 1

Query:   76 MEKLILLLLGFVVIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            M+K ++L++  V+ +    QCGC ++  KL TR  +N+ +GDMLL   DI IINGFK+H   ++ WP   V++ FA +FP DK   V+Q L ELQ DL NCV+F E   G +I V+++ +GCY+M+G TG   Q LNL+NP CM SKGTIKHEFIHALGFMHTHMR DRDN I+I W  I +SQC  F KC+GC  DG YET SVMHY+S+ F C      +++KNG  I YNH TT NDL M
Sbjct:    5 MQKFLILIV-LVLANEVASQCGCNKK--KLMTRATENLHVGDMLLSKADIAIINGFKHHQREARAWPGGKVSFAFANDFPADKRNLVKQCLNELQSDLGNCVQFFESTQGPHIAVHAQNKGCYAMIGCTGERGQFLNLQNPWCMNSKGTIKHEFIHALGFMHTHMRMDRDNFISINWRNIQSSQCFNFVKCEGCIMDGNYETRSVMHYSSDAFGCQQGMNTMIQKNGNLIDYNHNTTPNDLSM 244

[Close]

BLAST of Ast2 protein vs. TrEMBL
Match: A0A060Q750 (Metalloendopeptidase OS=Schmidtea mediterranea OX=79327 GN=Ast5 PE=2 SV=1)

HSP 1 Score: 224.942 bits (572), Expect = 2.426e-69
Identity = 115/246 (46.75%), Postives = 152/246 (61.79%), Query Frame = 1

Query:   73 FMEKLILLLLGFVVIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTG--GPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            F+   +L +L  V I+   G+CGC +  +K   R + ++K+ DMLLD  D+  I GF+ +  N+++W +N + YTF   FP DK Q VR+S+ EL  DL+ CVK+ E  +G++I+V S + GC+S +G+    G SQ LNLENPGC+YSKGTIKHEFIHA GFMHT MR DRD  + I W+RI +  C  F  C  CE    Y+T SVMHY SE F C      +V K    I YNH T   D QM
Sbjct:    5 FIGLFLLSILNLVFIE--AGKCGCQKSKLK---RAI-SLKIDDMLLDHVDLMKIEGFRGYDKNARRWTDNTLKYTFHPQFPADKKQIVRESMNELTNDLKGCVKYVESTSGYHIKVQSHQPGCWSFVGMLNKQGGSQELNLENPGCLYSKGTIKHEFIHATGFMHTQMRADRDKFVNIFWERIDSDFCHAFVTCKNCEETVTYKTNSVMHYPSESFPCPGQRITMVDKQNKEIPYNHGTIEEDHQM 244

[Close]

BLAST of Ast2 protein vs. Ensembl Cavefish
Match: c6ast1 (low choriolytic enzyme-like [Source:NCBI gene;Acc:111191947])

HSP 1 Score: 109.383 bits (272), Expect = 6.098e-28
Identity = 78/221 (35.29%), Postives = 112/221 (50.68%), Query Frame = 1

Query:  184 NVKMGDMLLDST----DIQIINGFKN-HYANSKK----WP-----NNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQ-EGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVV-VKKNGGAIGYNHETTANDL 798
            N  +G  L D T    DI + +G +N     S+K    WP     N  + Y  +  F  ++   +   L   +K    C++F+   R   YI+V S  EGCYS +G TGG  Q L+L++ GC+Y K  I+HEF+HALGF H   R DRD HI I ++ I   +   F K D    + PY+  SVMHY  + F+ N    +V +     A+G   E +AND+
Sbjct:   43 NRNIGQTLEDPTIRFGDILVDDGLQNADRCTSRKPSCMWPMNSDGNTYIPYIISNQFSPNEKDLITSVLKTFEK--STCIRFKPRDREEDYIDVQS-LEGCYSFVGRTGG-RQTLSLKSRGCLYKK-IIQHEFLHALGFHHEQCRSDRDKHIRILYENIDPGKEHNFDKKDTNNLNTPYDYGSVMHYGRDAFSRNGQPTMVPIPNQNVAVGRAEEMSANDI 258

[Close]

BLAST of Ast2 protein vs. Ensembl Cavefish
Match: c6ast1 (low choriolytic enzyme-like [Source:NCBI gene;Acc:111191947])

HSP 1 Score: 109.383 bits (272), Expect = 8.221e-28
Identity = 78/221 (35.29%), Postives = 112/221 (50.68%), Query Frame = 1

Query:  184 NVKMGDMLLDST----DIQIINGFKN-HYANSKK----WP-----NNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQ-EGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVV-VKKNGGAIGYNHETTANDL 798
            N  +G  L D T    DI + +G +N     S+K    WP     N  + Y  +  F  ++   +   L   +K    C++F+   R   YI+V S  EGCYS +G TGG  Q L+L++ GC+Y K  I+HEF+HALGF H   R DRD HI I ++ I   +   F K D    + PY+  SVMHY  + F+ N    +V +     A+G   E +AND+
Sbjct:   54 NRNIGQTLEDPTIRFGDILVDDGLQNADRCTSRKPSCMWPMNSDGNTYIPYIISNQFSPNEKDLITSVLKTFEK--STCIRFKPRDREEDYIDVQS-LEGCYSFVGRTGG-RQTLSLKSRGCLYKK-IIQHEFLHALGFHHEQCRSDRDKHIRILYENIDPGKEHNFDKKDTNNLNTPYDYGSVMHYGRDAFSRNGQPTMVPIPNQNVAVGRAEEMSANDI 269

[Close]

BLAST of Ast2 protein vs. Ensembl Cavefish
Match: npsn (low choriolytic enzyme-like [Source:NCBI gene;Acc:111191946])

HSP 1 Score: 105.916 bits (263), Expect = 1.815e-26
Identity = 73/216 (33.80%), Postives = 108/216 (50.00%), Query Frame = 1

Query:  187 VKMGDMLLDSTDIQIINGFKN-HYANSKK----WP-----NNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQ-EGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVV-VKKNGGAIGYNHETTANDL 798
            ++ GD+L+D       +G +N     S+K    WP     N  + Y  +  F   +   +   L   +K    C++F+   R   YI+V S  EGCYS +G TGG  Q L+L   GC++ K  I+HE +HALGF H   R DRD HI I ++ I+  +   F K D    + PY+  SVMHY  + F+ N    +V +     A+G   E +AND+
Sbjct:   66 IRFGDILVD-------DGLQNADRCTSRKPSCMWPRNSDGNTYIPYIISNQFRPKQKDLITSVLKTFEK--STCIRFKPRDREEDYIDVQSL-EGCYSFVGRTGG-GQTLSLNRRGCLHKK-IIQHELLHALGFHHEQCRSDRDQHIRILYENIIPGEEHNFDKEDTNNLNTPYDYGSVMHYERDAFSRNGQPTMVPIPDQNVAVGRAEEMSANDI 269

[Close]

BLAST of Ast2 protein vs. Ensembl Cavefish
Match: ENSAMXT00000050470.1 (low choriolytic enzyme-like [Source:NCBI gene;Acc:103035835])

HSP 1 Score: 101.293 bits (251), Expect = 5.594e-25
Identity = 60/183 (32.79%), Postives = 91/183 (49.73%), Query Frame = 1

Query:  271 WPNN-----IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGG-AIGYNHETTANDL 798
            WP +      V Y  +  F   ++Q +++ L        +C++F+   N   YI + S R GCYS +G  G  +Q ++L+  GC+Y   T++HE +HALGF H   R DRDNHI + WD I+ S    F K        PY+  SVM Y+   F+ N    +V   N   + G   + + ND+
Sbjct:   72 WPKSSDGKVYVPYIISNQFASRELQVIQRGLDSFSS--MSCIRFKRRSNERDYISIES-RSGCYSYIGRLGN-AQTVSLDRNGCIY-HNTVQHELLHALGFNHEQTRSDRDNHIRVVWDNIIDSMKHNFNKIATLNQGTPYDYNSVMQYHRTAFSKNGQPTMVPIPNSNVSFGQASQMSQNDI 249

[Close]

BLAST of Ast2 protein vs. Ensembl Cavefish
Match: ENSAMXT00000021327.2 (low choriolytic enzyme-like [Source:NCBI gene;Acc:103035835])

HSP 1 Score: 100.908 bits (250), Expect = 9.537e-25
Identity = 59/183 (32.24%), Postives = 92/183 (50.27%), Query Frame = 1

Query:  271 WPNN-----IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVV-VKKNGGAIGYNHETTANDL 798
            WP +      V Y  +  F   ++Q +++ L        +C++F+   N   YI + S R GCYS +G  G  +Q ++L+  GC+Y   T++HE +HALGF H   R DRDNHI + WD I+ S    F K        PY+  SVM Y+   F+ N    +V +  +  + G   + + ND+
Sbjct:   61 WPKSSDGKVYVPYIISNQFASRELQVIQRGLDSFSS--MSCIRFKRRSNERDYISIES-RSGCYSYIGRLGN-AQTVSLDRNGCIY-HNTVQHELLHALGFNHEQTRSDRDNHIRVVWDNIIDSMKHNFNKIATLNQGTPYDYNSVMQYHRTAFSKNGQPTMVPIPNSNVSFGQASQMSQNDI 238

[Close]

BLAST of Ast2 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007253.1 (pep scaffold:Pmarinus_7.0:GL476910:54360:144194:-1 gene:ENSPMAG00000006538.1 transcript:ENSPMAT00000007253.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 75.0998 bits (183), Expect = 2.052e-15
Identity = 49/157 (31.21%), Postives = 73/157 (46.50%), Query Frame = 1

Query:  259 NSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFA 717
            + + WP  ++ Y   GNF   +    RQ++   +K    CV F E  +   YI    +  GC S +G  GG  Q +++      +  G + HE  H +GF H H R DRD+H+TI    I   Q   F K +  E D     Y+ +S+MHY    F+
Sbjct:   18 SERIWPGGVIPYIVGGNFTGSQKAMFRQAMRHWEK--HTCVTFIERTDEESYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKF--GIVVHELGHVIGFWHEHTRPDRDDHVTIIKANIQPGQEYNFLKMEPGEVDSLGESYDFDSIMHYARNTFS 170

[Close]

BLAST of Ast2 protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004913.1 (pep scaffold:Pmarinus_7.0:GL478359:22377:26907:1 gene:ENSPMAG00000004462.1 transcript:ENSPMAT00000004913.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.6102 bits (135), Expect = 3.407e-10
Identity = 34/100 (34.00%), Postives = 53/100 (53.00%), Query Frame = 1

Query:  439 CYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG-PYETESVMHYNSEGFACNPSEK 735
            C+S +G+ G   Q +++   GC    GT+ HE  HA+G++H   R DRD  I++    +   Q  QF      +P G PY+ +SVMHY+    AC   ++
Sbjct:    1 CWSFVGMIGVGEQVVSIGR-GCE-GVGTVAHELGHAVGYVHEQSRPDRDAFISVLEGNVQDGQLPQFAVYSATDPRGVPYDLKSVMHYSRNVRACGTRDR 98

[Close]

BLAST of Ast2 protein vs. Ensembl Nematostella
Match: EDO41420 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4I5])

HSP 1 Score: 95.9005 bits (237), Expect = 1.044e-23
Identity = 57/181 (31.49%), Postives = 88/181 (48.62%), Query Frame = 1

Query:  268 KWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQ 801
            +WP  ++ YT   +     +  +R  + ++  D   C++F+E  N +      +  GC SM+G TG   Q ++L   GC Y  GT+ HE  HALGF H   R DRDN++TI W+ I  +    F        D    PY+  SVMHY    F+ N    +  K++G  +G   + +  D+Q
Sbjct:   40 RWPEGVMAYTIDRSLSNRAMNAIRAGM-KMWTD-NTCIRFKERTNEYAYARFWRGRGCSSMVGRTG-RRQDISLAG-GCWY-PGTVAHEIGHALGFYHEQSRPDRDNYVTIHWNNISPNMKFNFNMYPRSTIDSLGTPYDYRSVMHYQGNAFSSNGRATITAKQSGVTLGNRRQLSKVDIQ 215

[Close]

BLAST of Ast2 protein vs. Ensembl Nematostella
Match: EDO37770 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEU5])

HSP 1 Score: 97.0561 bits (240), Expect = 2.051e-23
Identity = 66/199 (33.17%), Postives = 96/199 (48.24%), Query Frame = 1

Query:  196 GDMLLDSTDIQIIN-----GFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTK--CDGCEPDG-PYETESVMHYNSEGFACNPSEKVVVKKNGGAIG 768
            GDM+L     Q +N       +    + KKWPN I+ Y    +      + V Q+    + + + CV+FQ+           K +GC+S +G+    +Q ++L   GC + KGT  HE  HALGF H   R DRDN++T+ WD I T     F K   D     G PY+  S+MHY +  F+ N    +  KK+G  IG
Sbjct:   34 GDMILTPDQQQAVNNGDLGASRGAPIHDKKWPNAILPYEIRSDLKGTPAEGVIQN-AMREWESKTCVRFQKRTTQKNYVYFFKGDGCWSYVGMLDRGAQAISL-GSGC-WHKGTAAHEIGHALGFYHEQSRPDRDNYVTVHWDNIKTDSKHNFNKYSADRINTFGTPYDFGSLMHYGTNYFSVNGRATITPKKSGAKIG 229

[Close]

BLAST of Ast2 protein vs. Ensembl Nematostella
Match: EDO42421 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1T1])

HSP 1 Score: 92.0485 bits (227), Expect = 1.803e-22
Identity = 61/186 (32.80%), Postives = 94/186 (50.54%), Query Frame = 1

Query:  265 KKWPNNIVTYTFAGNFPQDK--IQTVRQSLGELQKDLQNCVKFQE--GRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQ 801
            K WP  +V Y     F +    ++ + Q++ + +K    C++F++    +  Y+ +   R GC S +G  GG  Q L+L + GC + KGTI HE  HALGF H   R DRD+++TI ++ I     S F K    E D    PY+  S+MHY  + F+ N    +V KK G   G     +  D++
Sbjct:   10 KLWPGGVVVYELDPRFERSSRAMEKLTQAISDYEK--YTCIRFRKKTANDNDYVYIKD-RGGCRSHVGRKGG-KQYLSLSS-GC-WHKGTIIHELGHALGFFHEQTRPDRDDYVTILFENIRLGMASNFMKHSAGEVDSLGTPYDYGSIMHYGPKIFSANGKPTIVAKKPGVKFGQRDGLSPIDIK 189

[Close]

BLAST of Ast2 protein vs. Ensembl Nematostella
Match: EDO34721 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNJ4])

HSP 1 Score: 92.4337 bits (228), Expect = 3.812e-22
Identity = 70/211 (33.18%), Postives = 104/211 (49.29%), Query Frame = 1

Query:  196 GDMLLDSTDIQIINGFKNHYANS-----KKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRN-GHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPD---GPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQ 801
            GD+ LDS+  +I++   +    +       WPN  + Y F G       +  R ++ E + +   C++F E  +   YI V S+  GC+S +G +GG  Q L+L    C   KGT  HE +H LGF H   R+DRDN+ITI WD I + +   F K +  + D    PY+  S+MHY    F+ N    +V K    +IG     +  DLQ
Sbjct:    4 GDIYLDSSTTRIMDQLMSPSREALVDPVSHWPNGRLPYKF-GAVSNSVKEAFRAAIDEYEAN--TCIRFVERTDETDYILVVSE-GGCWSPIGRSGG-QQKLSL-GTYCD-RKGTAMHELMHTLGFFHEQSRRDRDNYITIHWDNIQSDKQFNFQKYEHGKVDTLGAPYDYGSIMHYPMFAFSSNGRATIVPKDPTASIGQRSGFSKVDLQ 207

[Close]

BLAST of Ast2 protein vs. Ensembl Nematostella
Match: EDO30445 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0S0])

HSP 1 Score: 89.3521 bits (220), Expect = 4.630e-21
Identity = 68/211 (32.23%), Postives = 106/211 (50.24%), Query Frame = 1

Query:  184 NVKMGDMLLDSTDIQIINGFKNHYAN-SKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDG---PYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQ 801
            +V  GD+ LD +   I+   ++  ++ ++ W N  V Y F G+   +       ++ E +   + CV+F   R    YI + S+  GC+S +G +GG  Q L+L   GC + +GT  HE +HA+GF H   R DRD++ITI WD I       F K    E D     Y+ +S+MHY    F  N  +  ++ +NG  IG     +A D+Q
Sbjct:    1 DVFEGDIYLDRSTKAILGMGRDAMSSPARHWLNARVPYVF-GSVSSEVRSVFLAAIKEYEA--KTCVRFVPRRGERDYIYIVSE-GGCFSSIGRSGG-LQKLSL-GTGCEH-RGTAIHEMMHAIGFFHEQSRLDRDSYITIYWDNIKPGMEYNFRKYKRGEADTLGYAYDLKSIMHYPKYAFTKN-RQPTIIARNGANIGQRDSFSAIDIQ 203

[Close]

BLAST of Ast2 protein vs. Ensembl Medaka
Match: mc6ast4 (astacin like metallo-protease [Source:NCBI gene;Acc:100049317])

HSP 1 Score: 102.449 bits (254), Expect = 3.434e-25
Identity = 60/194 (30.93%), Postives = 100/194 (51.55%), Query Frame = 1

Query:  196 GDMLLDSTDIQIINGFKNH--YANSKKWPNNI-----VTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKF-QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKN 753
            G   L   DI +  G ++   +A S  W  ++     + YT + ++ +  ++ +++ +  +++    CV+F  +     Y+++  K  GC+S LG  GG  Q L+L+NP CM   G I HEF+HALGF+H   R DRDN+IT+ W  I   +   F K      D PY+  S+MH+    ++ +    +V K N
Sbjct:   62 GTTTLREGDIAVSTGRRSKMCFARSCLWSKSVDGHVYIAYTISPDYTEADVKLIKKGMENIEEG--TCVRFVPQTHQRDYVDIQPK-SGCWSYLGARGG-RQTLSLQNPDCM-QVGVISHEFMHALGFVHEQSRFDRDNYITVMWPNIWRDRLRNFEKFKTDSLDLPYDYGSIMHFGMYAYSMDGQPTLVAKNN 250

[Close]

BLAST of Ast2 protein vs. Ensembl Medaka
Match: mc6ast5 (astacin like metallo-protease [Source:NCBI gene;Acc:100049509])

HSP 1 Score: 99.7525 bits (247), Expect = 2.885e-24
Identity = 55/169 (32.54%), Postives = 85/169 (50.30%), Query Frame = 1

Query:  259 NSKKWPNNIVTYTFAGNFPQ---DKIQTVRQSLGELQKDLQNCVKF-QEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKN 753
            N+  WP ++  + +         D +  +    G        C+KF       H++++   R GC+S LG TGG SQ L+L+ PGCM+S G   HEF+HALGF+H   R DRD+++TI W  I+      F K      + PY+  SVMHY    F+ +    ++ + +
Sbjct:   89 NTCLWPKSVDGFVYVPYIVSPLYDDMDRITIETGMQDIASGTCIKFVPRTHEAHFLDIQ-PRYGCWSFLGQTGG-SQTLSLQTPGCMWS-GIAAHEFMHALGFVHEQSRSDRDHYVTIVWKNIMPDHAHNFRKQATNNLNSPYDYSSVMHYGRYAFSGDGGPTIIPRPD 254

[Close]

BLAST of Ast2 protein vs. Ensembl Medaka
Match: ENSORLT00000018637.2 (pep primary_assembly:ASM223467v1:3:32702055:32705063:-1 gene:ENSORLG00000014863.2 transcript:ENSORLT00000018637.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 96.2857 bits (238), Expect = 4.629e-23
Identity = 52/146 (35.62%), Postives = 79/146 (54.11%), Query Frame = 1

Query:  283 IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFA 717
            ++ Y  +  + + ++ T+  ++       + C++F    N + +I V SK  GCYS LG  GG  Q L+L   GCMYS G I+HE  HALGF H   R DRD+++ I W  I+ +    F K D    + PY+  S+MHY  + F+
Sbjct:   91 VIPYVISSQYSRGEVATIEGAMRAFNG--RTCIRFVRRTNEYDFISVVSK-NGCYSELGRKGG-QQELSLNRGGCMYS-GIIQHELNHALGFQHEQTRSDRDSYVRINWQNIIPASAYNFNKHDTNNLNTPYDYSSIMHYGRDAFS 231

[Close]

BLAST of Ast2 protein vs. Ensembl Medaka
Match: ENSORLT00000018649.2 (pep primary_assembly:ASM223467v1:3:32704054:32707947:-1 gene:ENSORLG00000014873.2 transcript:ENSORLT00000018649.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 96.2857 bits (238), Expect = 9.118e-23
Identity = 52/146 (35.62%), Postives = 79/146 (54.11%), Query Frame = 1

Query:  283 IVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGH-YIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFA 717
            ++ Y  +  + + ++ T+  ++       + C++F    N + +I V SK  GCYS LG  GG  Q L+L   GCMYS G I+HE  HALGF H   R DRD+++ I W  I+ +    F K D    + PY+  S+MHY  + F+
Sbjct:  100 VIPYVISSQYSRGEVATIEGAMRAFNG--RTCIRFVRRTNEYDFISVVSK-NGCYSELGRKGG-QQELSLNRGGCMYS-GIIQHELNHALGFQHEQTRSDRDSYVRINWQNIIPASAYNFNKHDTNNLNTPYDYSSIMHYGRDAFS 240

[Close]

BLAST of Ast2 protein vs. Ensembl Medaka
Match: lce (protease [Source:NCBI gene;Acc:100049451])

HSP 1 Score: 95.1301 bits (235), Expect = 1.244e-22
Identity = 67/220 (30.45%), Postives = 101/220 (45.91%), Query Frame = 1

Query:  160 KLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYA-NSKKWP---NNIVT--YTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKN-GGAIGYNHETTANDL 798
            ++    ++ +  GD++L  T     N  K   A +S +WP   N IV   Y  + N+  D+ +T+R ++ E  +  + C+ F    N         R GC SM+G  G   Q + L+  GC+     I+HE +HALGF H H R DRD H+ I W+ I+      F K D      PY+  S+MHY    F  +  E +    N   AIG     +  D+
Sbjct:   51 RMNNNSMEELLEGDLVLPKTR----NAMKCFGAPDSCRWPKSSNGIVKVPYVVSDNYESDEKETIRNAMKEFAE--KTCIHFVPRNNERAYLSLEPRFGCKSMMGYVGD-KQVVVLQRFGCI-KHAVIQHELLHALGFYHEHTRSDRDQHVKINWENIIKDFTHNFDKNDTDNLGTPYDYGSIMHYGRTAFGKDRKETITPIPNPKAAIGQTERMSDIDI 262

[Close]

BLAST of Ast2 protein vs. Planmine SMEST
Match: SMESG000072807.1 (SMESG000072807.1)

HSP 1 Score: 466.077 bits (1198), Expect = 4.260e-168
Identity = 221/231 (95.67%), Postives = 222/231 (96.10%), Query Frame = 1

Query:  112 VIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            +I Y      C  QSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM
Sbjct:    7 IIYYYQASSFCLIQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 237

[Close]

BLAST of Ast2 protein vs. Planmine SMEST
Match: SMESG000072805.1 (SMESG000072805.1)

HSP 1 Score: 466.077 bits (1198), Expect = 4.260e-168
Identity = 221/231 (95.67%), Postives = 222/231 (96.10%), Query Frame = 1

Query:  112 VIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            +I Y      C  QSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM
Sbjct:    7 IIYYYQASSFCLIQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 237

[Close]

BLAST of Ast2 protein vs. Planmine SMEST
Match: SMESG000072807.1 (SMESG000072807.1)

HSP 1 Score: 465.307 bits (1196), Expect = 8.845e-168
Identity = 221/231 (95.67%), Postives = 222/231 (96.10%), Query Frame = 1

Query:  112 VIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            +I Y      C  QSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM
Sbjct:    9 IIYYYQASSFCLIQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 239

[Close]

BLAST of Ast2 protein vs. Planmine SMEST
Match: SMESG000072805.1 (SMESG000072805.1)

HSP 1 Score: 465.307 bits (1196), Expect = 8.845e-168
Identity = 221/231 (95.67%), Postives = 222/231 (96.10%), Query Frame = 1

Query:  112 VIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            +I Y      C  QSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM
Sbjct:    9 IIYYYQASSFCLIQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 239

[Close]

BLAST of Ast2 protein vs. Planmine SMEST
Match: SMESG000072807.1 (SMESG000072807.1)

HSP 1 Score: 456.447 bits (1173), Expect = 2.286e-164
Identity = 219/231 (94.81%), Postives = 220/231 (95.24%), Query Frame = 1

Query:  112 VIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDIQIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 804
            +I Y      C  QSVKLRTRGLDNVKMGDMLLDSTDIQIING  NHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM
Sbjct:    7 IIYYYQASSFCLIQSVKLRTRGLDNVKMGDMLLDSTDIQIING--NHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQNCVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTIKHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPYETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQM 235

The following BLAST results are available for this feature:

BLAST of Ast2 protein vs. Ensembl Human
BLAST of Ast2 protein vs. Ensembl Celegans
BLAST of Ast2 protein vs. Ensembl Fly
BLAST of Ast2 protein vs. Ensembl Zebrafish
BLAST of Ast2 protein vs. Ensembl Xenopus
BLAST of Ast2 protein vs. Ensembl Mouse
BLAST of Ast2 protein vs. UniProt/SwissProt
BLAST of Ast2 protein vs. TrEMBL
BLAST of Ast2 protein vs. Ensembl Cavefish
BLAST of Ast2 protein vs. Ensembl Sea Lamprey
BLAST of Ast2 protein vs. Ensembl Yeast
BLAST of Ast2 protein vs. Ensembl Nematostella
BLAST of Ast2 protein vs. Ensembl Medaka
BLAST of Ast2 protein vs. Planmine SMEST

BLAST of Ast2 protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ASTL	8.552e-17	30.86	astacin like metalloendopeptidase [Source:HGNC Sym...	[more]
MEP1B	2.684e-14	30.96	meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC...	[more]
MEP1B	2.783e-14	30.96	meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC...	[more]
TLL2	4.198e-14	31.37	tolloid like 2 [Source:HGNC Symbol;Acc:HGNC:11844]	[more]
MEP1A	4.671e-14	29.95	meprin A subunit alpha [Source:HGNC Symbol;Acc:HGN...	[more]

BLAST of Ast2 protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nas-4	9.834e-25	32.04	Zinc metalloproteinase nas-4 [Source:UniProtKB/Sw...	[more]
nas-4	3.020e-24	31.88	Zinc metalloproteinase nas-4 [Source:UniProtKB/Sw...	[more]
nas-4	3.453e-24	31.88	Zinc metalloproteinase nas-4 [Source:UniProtKB/Sw...	[more]
nas-6	5.239e-21	33.33	Zinc metalloproteinase nas-6 [Source:UniProtKB/Sw...	[more]
nas-15	1.525e-20	34.21	Zinc metalloproteinase nas-15 [Source:UniProtKB/S...	[more]

BLAST of Ast2 protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG6763	7.170e-35	34.55	gene:FBgn0039069 transcript:FBtr0084378	[more]
CG6763	7.170e-35	34.55	gene:FBgn0039069 transcript:FBtr0334497	[more]
CG11865	4.879e-23	28.63	gene:FBgn0028947 transcript:FBtr0080753	[more]
CG15255	5.491e-22	30.46	gene:FBgn0028950 transcript:FBtr0080785	[more]
CG15255	5.491e-22	30.46	gene:FBgn0028950 transcript:FBtr0343719	[more]

BLAST of Ast2 protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
c6ast3	1.674e-24	32.95	six-cysteine containing astacin protease 3 [Source...	[more]
c6ast3	1.674e-24	32.95	six-cysteine containing astacin protease 3 [Source...	[more]
hce2l1	2.472e-23	31.76	high choriolytic enzyme 2-like 1 [Source:ZFIN;Acc:...	[more]
c6ast4	3.883e-23	31.79	six-cysteine containing astacin protease 4 [Source...	[more]
c6ast4	3.883e-23	31.79	six-cysteine containing astacin protease 4 [Source...	[more]

BLAST of Ast2 protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kpna4	1.627e-21	32.14	karyopherin alpha 4 (importin alpha 3) [Source:Xen...	[more]
polr2l.2	3.836e-20	34.30	polymerase (RNA) II (DNA directed) polypeptide L, ...	[more]
ENSXETT00000022029.1	4.129e-20	32.53	astacin-like metalloendopeptidase [Source:NCBI gen...	[more]
ENSXETT00000032332.1	6.679e-20	33.13	astacin-like metallo-endopeptidase 3 gene b1 [Sour...	[more]
ENSXETT00000032191.1	9.959e-20	33.13	astacin-like metallo-endopeptidase 3 gene b1 [Sour...	[more]

BLAST of Ast2 protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mep1a	1.124e-15	31.96	meprin 1 alpha [Source:MGI Symbol;Acc:MGI:96963]	[more]
Mep1a	1.203e-15	31.96	meprin 1 alpha [Source:MGI Symbol;Acc:MGI:96963]	[more]
Mep1b	5.286e-15	30.10	meprin 1 beta [Source:MGI Symbol;Acc:MGI:96964]	[more]
Tll2	2.307e-14	27.23	tolloid-like 2 [Source:MGI Symbol;Acc:MGI:1346044]	[more]
Tll2	2.615e-14	27.23	tolloid-like 2 [Source:MGI Symbol;Acc:MGI:1346044]	[more]

BLAST of Ast2 protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P55112\|NAS4_CAEEL	1.251e-23	32.04	Zinc metalloproteinase nas-4 OS=Caenorhabditis ele...	[more]
sp\|P31581\|HCE2_ORYLA	5.790e-22	35.62	High choriolytic enzyme 2 OS=Oryzias latipes OX=80...	[more]
sp\|P31579\|LCE_ORYLA	1.260e-21	30.45	Low choriolytic enzyme OS=Oryzias latipes OX=8090 ...	[more]
sp\|P31580\|HCE1_ORYLA	2.021e-21	34.93	High choriolytic enzyme 1 OS=Oryzias latipes OX=80...	[more]
sp\|Q9U3S9\|NAS6_CAEEL	6.664e-20	33.33	Zinc metalloproteinase nas-6 OS=Caenorhabditis ele...	[more]

BLAST of Ast2 protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A060Q714	0.000e+0	100.00	Metalloendopeptidase OS=Schmidtea mediterranea OX=...	[more]
A0A060Q785	3.925e-138	76.23	Metalloendopeptidase OS=Schmidtea mediterranea OX=...	[more]
A0A060Q786	3.991e-122	68.72	Metalloendopeptidase OS=Schmidtea mediterranea OX=...	[more]
I1ZIC3	4.618e-88	53.50	Metalloendopeptidase OS=Schmidtea mediterranea OX=...	[more]
A0A060Q750	2.426e-69	46.75	Metalloendopeptidase OS=Schmidtea mediterranea OX=...	[more]

BLAST of Ast2 protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
c6ast1	6.098e-28	35.29	low choriolytic enzyme-like [Source:NCBI gene;Acc:...	[more]
c6ast1	8.221e-28	35.29	low choriolytic enzyme-like [Source:NCBI gene;Acc:...	[more]
npsn	1.815e-26	33.80	low choriolytic enzyme-like [Source:NCBI gene;Acc:...	[more]
ENSAMXT00000050470.1	5.594e-25	32.79	low choriolytic enzyme-like [Source:NCBI gene;Acc:...	[more]
ENSAMXT00000021327.2	9.537e-25	32.24	low choriolytic enzyme-like [Source:NCBI gene;Acc:...	[more]

BLAST of Ast2 protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000007253.1	2.052e-15	31.21	pep scaffold:Pmarinus_7.0:GL476910:54360:144194:-1...	[more]
ENSPMAT00000004913.1	3.407e-10	34.00	pep scaffold:Pmarinus_7.0:GL478359:22377:26907:1 g...	[more]

BLAST of Ast2 protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Ast2 protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO41420	1.044e-23	31.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37770	2.051e-23	33.17	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42421	1.803e-22	32.80	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34721	3.812e-22	33.18	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO30445	4.630e-21	32.23	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ast2 protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mc6ast4	3.434e-25	30.93	astacin like metallo-protease [Source:NCBI gene;Ac...	[more]
mc6ast5	2.885e-24	32.54	astacin like metallo-protease [Source:NCBI gene;Ac...	[more]
ENSORLT00000018637.2	4.629e-23	35.62	pep primary_assembly:ASM223467v1:3:32702055:327050...	[more]
ENSORLT00000018649.2	9.118e-23	35.62	pep primary_assembly:ASM223467v1:3:32704054:327079...	[more]
lce	1.244e-22	30.45	protease [Source:NCBI gene;Acc:100049451]	[more]

BLAST of Ast2 protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000072807.1	4.260e-168	95.67	SMESG000072807.1	[more]
SMESG000072805.1	4.260e-168	95.67	SMESG000072805.1	[more]
SMESG000072807.1	8.845e-168	95.67	SMESG000072807.1	[more]
SMESG000072805.1	8.845e-168	95.67	SMESG000072805.1	[more]
SMESG000072807.1	2.286e-164	94.81	SMESG000072807.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30005126
GenBank	CCW36840.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30005126 ID=SMED30005126|Name=Ast2 protein|organism=Schmidtea mediterranea sexual|type=transcript|length=882bp
TGGAGACGAACTTCCTGTTTACGTTGCTGCAAGAGAATCGTATAAAAACC
GGAAGCATTCAGTATCAACACATTCATGGAAAAATTAATTCTCTTACTTT
TAGGATTTGTTGTGATTGACTATGCCAACGGCCAATGTGGATGTCCACGT
CAATCGGTGAAGCTGAGAACGAGAGGTCTCGACAATGTCAAGATGGGAGA
CATGCTTTTGGATTCCACAGATATACAGATCATCAATGGGTTCAAGAATC
ATTACGCAAACAGCAAGAAGTGGCCCAACAACATCGTCACGTATACATTT
GCAGGAAACTTCCCTCAAGACAAGATCCAAACTGTGCGACAATCTCTAGG
AGAATTACAGAAAGATTTACAAAACTGTGTCAAGTTTCAAGAAGGAAGAA
ACGGACATTACATCGAAGTCAACTCGAAACGTGAAGGATGTTATTCTATG
TTGGGAGTCACAGGAGGTCCTAGTCAGCCGTTGAATCTTGAAAACCCTGG
ATGTATGTATTCAAAAGGAACGATCAAACACGAGTTTATCCACGCCCTCG
GATTCATGCACACCCACATGAGAAAGGACAGAGACAACCACATCACTATC
AAATGGGACAGAATCCTCACAAGTCAATGCAGTCAGTTTACGAAATGCGA
CGGATGCGAACCCGACGGACCGTACGAGACTGAGAGCGTCATGCATTACA
ACAGCGAAGGATTCGCTTGTAATCCAAGCGAGAAAGTCGTGGTGAAGAAA
AATGGAGGAGCGATCGGATACAATCACGAGACGACAGCCAATGATTTGCA
AATGATCAAGAATTTTTACAACTGCAAATAAAATTATATAAATAATAAAT
AAATTATTTATCTTGAAAAAAAAAGATCGGAA

protein sequence of SMED30005126-orf-1

>SMED30005126-orf-1 ID=SMED30005126-orf-1|Name=SMED30005126-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=252bp
MEKLILLLLGFVVIDYANGQCGCPRQSVKLRTRGLDNVKMGDMLLDSTDI
QIINGFKNHYANSKKWPNNIVTYTFAGNFPQDKIQTVRQSLGELQKDLQN
CVKFQEGRNGHYIEVNSKREGCYSMLGVTGGPSQPLNLENPGCMYSKGTI
KHEFIHALGFMHTHMRKDRDNHITIKWDRILTSQCSQFTKCDGCEPDGPY
ETESVMHYNSEGFACNPSEKVVVKKNGGAIGYNHETTANDLQMIKNFYNC
K*

Aliases

The feature 'Ast2 protein' has the following synonyms


Synonym
Ast2

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head
PLANA:0000429	neoblast

Vocabulary: **INTERPRO**
Term	Definition
IPR001506	Peptidase_M12A
IPR006026	Peptidase_Metallo
IPR024079	MetalloPept_cat_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0004222	metalloendopeptidase activity
GO:0008270	zinc ion binding
GO:0008237	metallopeptidase activity
GO:0008233	peptidase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0006508	proteolysis

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001506	Peptidase M12A	PRINTS	PR00480	ASTACIN	coord: 199..214 score: 43.33 coord: 236..249 score: 22.26 coord: 144..162 score: 45.61 coord: 163..180 score: 41.76
IPR001506	Peptidase M12A	PFAM	PF01400	Astacin	coord: 64..251 e-value: 1.3E-42 score: 145.6
IPR006026	Peptidase, metallopeptidase	SMART	SM00235	col_5	coord: 62..204 e-value: 7.1E-23 score: 92.0
IPR024079	Metallopeptidase, catalytic domain superfamily	GENE3D	G3DSA:3.40.390.10		coord: 21..251 e-value: 1.7E-50 score: 173.7
None	No IPR available	PANTHER	PTHR10127	DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING	coord: 39..250
None	No IPR available	PROSITE	PS51864	ASTACIN	coord: 54..251 score: 45.473
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..19 score: 0.808
None	No IPR available	SUPERFAMILY	SSF55486	Metalloproteases ("zincins"), catalytic domain	coord: 62..250

Main menu

Ast2 protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Owlery

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