Innexin

Overview
NameInnexin
Smed IDSMED30005081
Length (bp)2445
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30005081) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30005081) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30005081) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30005081) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30005081

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30005081h1SMcG0013413 SmedASXL_014226SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30005081h1SMcG0013413 SmedASXL_037164SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30005081h1SMcG0013413 dd_Smed_v4_15435_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30005081h1SMcG0013413 dd_Smed_v4_15435_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30005081h1SMcG0013413 dd_Smed_v4_15435_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30005081h1SMcG0013413 dd_Smed_v6_15502_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 186.037 bits (471), Expect = 9.410e-52
Identity = 96/247 (38.87%), Postives = 152/247 (61.54%), Query Frame = 1 
Query:  220 DFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWR-----VASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            DFVDKLN+ +T AII     ++SA+QY+G PIQCWVP +FT AWE+Y EN CWV NTY+L      P++  + +  + ISYYQW+  VLA +AL  ++P + WR      +   +  L + A +A + D D R   V  +   +E   DA    R V  +   C+     N  +T+L++ ++++++GN V Q++++  F+G++N+ +G+ +L+DLL G++WE++GNFPRVT C   VR +G V   +
Sbjct:   20 DFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGD-RRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHME---DALEIQREVTDVSGMCVQKRWAN-YVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHT 261
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 186.037 bits (471), Expect = 9.410e-52
Identity = 96/247 (38.87%), Postives = 152/247 (61.54%), Query Frame = 1 
Query:  220 DFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWR-----VASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            DFVDKLN+ +T AII     ++SA+QY+G PIQCWVP +FT AWE+Y EN CWV NTY+L      P++  + +  + ISYYQW+  VLA +AL  ++P + WR      +   +  L + A +A + D D R   V  +   +E   DA    R V  +   C+     N  +T+L++ ++++++GN V Q++++  F+G++N+ +G+ +L+DLL G++WE++GNFPRVT C   VR +G V   +
Sbjct:   20 DFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGD-RRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHME---DALEIQREVTDVSGMCVQKRWAN-YVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHT 261
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 184.882 bits (468), Expect = 6.096e-51
Identity = 96/247 (38.87%), Postives = 152/247 (61.54%), Query Frame = 1 
Query:  220 DFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWR-----VASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            DFVDKLN+ +T AII     ++SA+QY+G PIQCWVP +FT AWE+Y EN CWV NTY+L      P++  + +  + ISYYQW+  VLA +AL  ++P + WR      +   +  L + A +A + D D R   V  +   +E   DA    R V  +   C+     N  +T+L++ ++++++GN V Q++++  F+G++N+ +G+ +L+DLL G++WE++GNFPRVT C   VR +G V   +
Sbjct:   20 DFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGD-RRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHME---DALEIQREVTDVSGMCVQKRWANY-VTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHT 261
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 169.088 bits (427), Expect = 1.207e-45
Identity = 94/255 (36.86%), Postives = 149/255 (58.43%), Query Frame = 1 
Query:  220 DFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWR-----VASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTR--------LTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            DFVDKLN+ +T  I+     L+SA+QY+G PIQCWVP  FT A E+Y EN CWV NTY++   ++IP +    +N + I YYQW+  +LA +ALL +VP + WR      +   L  L++ A +A L D +++ + V  M   ++++   T   R  +G  R C   L             +T+L+I +++++  N + Q +L+   +GSN++ +G++LLKDL+   +WE TG FPRVT C   VR +G + + +
Sbjct:   20 DFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRN-RQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDR--QGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHT 271
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393])

HSP 1 Score: 167.548 bits (423), Expect = 2.783e-45
Identity = 97/249 (38.96%), Postives = 149/249 (59.84%), Query Frame = 1 
Query:  220 DFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVAS----RRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQ---ADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            D +DKLN+ +T AII +   L+SA+QY+G PIQCWVP  FT+  E+Y EN CWV NTYFL     IP +  E +N + I YYQW+  VLA +ALL +VP + WR+ S      +  L++ A ++ L D + R +A+  +  ++EE        M   R+K +    +        +T L+I V+I++  N VGQI+L+  F+G+ +  +G  +L DL+ G++WE +G+FPRVT C   V+ +G V + +
Sbjct:   22 DIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAEREN-RQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLK-LLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHT 268
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860)

HSP 1 Score: 58.151 bits (139), Expect = 1.429e-8
Identity = 55/221 (24.89%), Postives = 85/221 (38.46%), Query Frame = 1 
Query:  292 RQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEF------------KNVKYISYYQWIVIVLAGQALLSWVPHLAWRV-ASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGN---FPRVTYCT 906
            RQYIG PI C V +      + Y    CW+ +T F + ++   +  ++               VKY  YYQW+  VL  QA+L +VP   W+     RL +L+      ++ D                       +  R K +    +G L  +      F V   +   N +GQIY +  F+      +G  +LK      D  +      FP+VT CT
Sbjct:   45 RQYIGDPIDCIVDEIPLGVMDTY----CWIYST-FTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSWEGGRLKMLVMDLNSPIVNDE---------------------CKNDRKKILVDYFIGNLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCT 239
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005)

HSP 1 Score: 58.151 bits (139), Expect = 1.429e-8
Identity = 55/221 (24.89%), Postives = 85/221 (38.46%), Query Frame = 1 
Query:  292 RQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEF------------KNVKYISYYQWIVIVLAGQALLSWVPHLAWRV-ASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGN---FPRVTYCT 906
            RQYIG PI C V +      + Y    CW+ +T F + ++   +  ++               VKY  YYQW+  VL  QA+L +VP   W+     RL +L+      ++ D                       +  R K +    +G L  +      F V   +   N +GQIY +  F+      +G  +LK      D  +      FP+VT CT
Sbjct:   45 RQYIGDPIDCIVDEIPLGVMDTY----CWIYST-FTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSWEGGRLKMLVMDLNSPIVNDE---------------------CKNDRKKILVDYFIGNLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCT 239
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314)

HSP 1 Score: 58.151 bits (139), Expect = 1.429e-8
Identity = 55/221 (24.89%), Postives = 85/221 (38.46%), Query Frame = 1 
Query:  292 RQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEF------------KNVKYISYYQWIVIVLAGQALLSWVPHLAWRV-ASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGN---FPRVTYCT 906
            RQYIG PI C V +      + Y    CW+ +T F + ++   +  ++               VKY  YYQW+  VL  QA+L +VP   W+     RL +L+      ++ D                       +  R K +    +G L  +      F V   +   N +GQIY +  F+      +G  +LK      D  +      FP+VT CT
Sbjct:   45 RQYIGDPIDCIVDEIPLGVMDTY----CWIYST-FTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSWEGGRLKMLVMDLNSPIVNDE---------------------CKNDRKKILVDYFIGNLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCT 239
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006)

HSP 1 Score: 58.151 bits (139), Expect = 1.429e-8
Identity = 55/221 (24.89%), Postives = 85/221 (38.46%), Query Frame = 1 
Query:  292 RQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEF------------KNVKYISYYQWIVIVLAGQALLSWVPHLAWRV-ASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGN---FPRVTYCT 906
            RQYIG PI C V +      + Y    CW+ +T F + ++   +  ++               VKY  YYQW+  VL  QA+L +VP   W+     RL +L+      ++ D                       +  R K +    +G L  +      F V   +   N +GQIY +  F+      +G  +LK      D  +      FP+VT CT
Sbjct:   45 RQYIGDPIDCIVDEIPLGVMDTY----CWIYST-FTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSWEGGRLKMLVMDLNSPIVNDE---------------------CKNDRKKILVDYFIGNLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCT 239
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0112571)

HSP 1 Score: 56.225 bits (134), Expect = 5.723e-8
Identity = 57/256 (22.27%), Postives = 103/256 (40.23%), Query Frame = 1 
Query:  187 NLFHLNYGGGVDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFL----LADQEIPV-------DDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGN---FPRVTYCTIL 912
            NL  +++      V +L++  T  I++    +I+ RQY+G PI C   ++     E+     CW+ +TY L    L  Q + V        D +  + K+  YYQW+   L  QA+L + P   W+               A++ D D+ + + +      +   D      R    +                + V  ++ + N +GQ++LM +F     I FG  ++  +   Q+  +      FPR+T CT  
Sbjct:   10 NLVKVSHVKTDSIVFRLHYSITVMILMSFSLIITTRQYVGNPIDCVHTKDIP---EDVLNTYCWIQSTYTLKSLFLKKQGVSVPYPGIGNSDGDPADKKHYKYYQWVCFCLFFQAILFYTPRWLWKSWE-------GGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWENLRYHNWW-------------AYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFF 242
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 167.548 bits (423), Expect = 3.540e-44
Identity = 97/249 (38.96%), Postives = 149/249 (59.84%), Query Frame = 1 
Query:  220 DFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVAS----RRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQ---ADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            D +DKLN+ +T AII +   L+SA+QY+G PIQCWVP  FT+  E+Y EN CWV NTYFL     IP +  E +N + I YYQW+  VLA +ALL +VP + WR+ S      +  L++ A ++ L D + R +A+  +  ++EE        M   R+K +    +        +T L+I V+I++  N VGQI+L+  F+G+ +  +G  +L DL+ G++WE +G+FPRVT C   V+ +G V + +
Sbjct:   22 DIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAEREN-RQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLK-LLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHT 268
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 3.038e-43
Identity = 94/255 (36.86%), Postives = 149/255 (58.43%), Query Frame = 1 
Query:  220 DFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWR-----VASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTR--------LTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            DFVDKLN+ +T  I+     L+SA+QY+G PIQCWVP  FT A E+Y EN CWV NTY++   ++IP +    +N + I YYQW+  +LA +ALL +VP + WR      +   L  L++ A +A L D +++ + V  M   ++++   T   R  +G  R C   L             +T+L+I +++++  N + Q +L+   +GSN++ +G++LLKDL+   +WE TG FPRVT C   VR +G + + +
Sbjct:  140 DFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRN-RQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDR--QGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHT 391
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2)

HSP 1 Score: 147.902 bits (372), Expect = 5.736e-37
Identity = 78/246 (31.71%), Postives = 137/246 (55.69%), Query Frame = 1 
Query:  220 DFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRR----LPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            D VD+L++  T  ++     ++S +QY+G  IQCW+P EF   WE+YAE+ C++ NT+F+    EIP D ++ +  + I YYQW+ IVLA QA + ++P   W    ++     P ++  A      D + R K V+ +V  + +  D   R++   G F     G    +  ++L+I +++M++ N   Q  ++ KF+G+   ++G+    DL AG++W+ +G FPRVT C   VR++  V + +
Sbjct:   22 DAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFIPERSEIPGDVEDRQKAE-IGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSVISEAEALRSQDSETRTKGVNKLVDFIGDILDT--RSKNEYGRFYCYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFSVRKLANVHRYT 264
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q27295|EAT5_CAEEL (Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN=eat-5 PE=2 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 5.841e-37
Identity = 79/250 (31.60%), Postives = 146/250 (58.40%), Query Frame = 1 
Query:  226 VDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPV----LLRSAREAVLPDRDLRVKAVSCMVASLEE------QADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
             D+LN+ ++  II+ +   I+ARQY+G P+QCWVP +FTKAWE+YAE+ C+V NTY++  + ++P+  +E  + + I YYQW   ++A +A   ++P + W + S +  +    L+ +A++A   + + R K +  +   +          + T +  +++ IF     G+     +T +++V +++++ N+  Q Y   KF+G N+  +G  +L D+L G DWE +GNFPR+  C   VR +G +++ S
Sbjct:   20 TDRLNYYYSTLIIMGMSLTITARQYVGSPLQCWVPAQFTKAWEQYAEDYCFVYNTYWVKPNDKVPLTVEERVSQQLI-YYQWAPFIMAIEAAFFYLPVIFWSMLSTKSGINIIKLVETAQKAEGAESEERKKQIDIICRHISNNLRKRRNEEETTKMAKIQRIF-----GMQHGKYITNVYLVTKLIYMTNSFLQFYSTNKFLGQNDPYWGMRILDDILKGTDWEHSGNFPRIAMCDFQVRVLGNLQRYS 263
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23027|INX5_CAEEL (Innexin-5 OS=Caenorhabditis elegans OX=6239 GN=inx-5 PE=3 SV=2)

HSP 1 Score: 142.51 bits (358), Expect = 5.981e-35
Identity = 77/255 (30.20%), Postives = 132/255 (51.76%), Query Frame = 1 
Query:  220 DFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLL------ADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVAS-------RRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            D  D+ ++Q+T  ++     +++A QY+G+PIQCWVP +FT+ WE+YAE  C++  TYFL        +  +   D        + YYQWI IVL  QA L ++P + WR  +       + L  +  ++R+      D +VKA        ++     +  R    +F+     +     L  L+++V+I+++ N V Q +++  F+ + + M+GW   +DL+AG++WE TG FPRVT C   +  +  V   S
Sbjct:   20 DIADRFSYQYTSTLLGFSAIMMAASQYVGRPIQCWVPAQFTRTWEKYAETYCFIKGTYFLPGAFASEGEMSVTSPDDAVTATPQVGYYQWIPIVLVLQAFLFYLPSIIWRTFNESCELKIKELAAVSEASRKIKSNMSDDQVKATKFGRYFFKK-----LNFRNESPVFKETGSVVASGKFLPALYLLVKILYLANIVLQFWILTYFLETKSWMWGWQTFQDLMAGREWETTGIFPRVTMCDFSIMDLTSVHDHS 269
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A5K4F2Z5 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 371.703 bits (953), Expect = 1.468e-119
Identity = 174/272 (63.97%), Postives = 223/272 (81.99%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGG-GVDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQASCFYLSNPR 969
            +D G + + G LF   YGG GVDF+D+LN+QFTG +++I I++IS RQY+GKPIQCWVPQEFTK+WEEYAENLCWVSNTYFLL ++EIP D  +++ VK+I YYQW+ IVLAGQA++SWVPHL WRV SRRLP+LL+SAREA +PDR+LR+KAVSC+VA+LEEQA++  R RR+K I  RCL G+ PN RLT+LF+ VR +F+ N+VGQIYLM++F G N+ +FG  LL+DL AG +WE TG+FPRVTYCTI VR+MGQ K AS   +++ R
Sbjct:    9 LDGGFVFKLGRLFKTPYGGEGVDFIDQLNYQFTGGLMVIFIAIISFRQYVGKPIQCWVPQEFTKSWEEYAENLCWVSNTYFLLPNEEIPTDQVDYEKVKFIGYYQWVAIVLAGQAMMSWVPHLLWRVGSRRLPLLLKSAREAAIPDRELRLKAVSCLVATLEEQAESQSRFRRIKSILTRCLCGVTPNARLTMLFLFVRALFVANSVGQIYLMKRFTGFNSTVFGLRLLQDLSAGVEWERTGHFPRVTYCTIKVRKMGQTKPASSETVTSIR 280
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A4S2LXE0 (Innexin OS=Opisthorchis felineus OX=147828 GN=inx PE=3 SV=1)

HSP 1 Score: 373.629 bits (958), Expect = 2.315e-118
Identity = 172/264 (65.15%), Postives = 221/264 (83.71%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGG-GVDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            +D G + + G LF   YGG GVDF+D+LN+Q+TG +++I I++IS RQY+GKPIQCWVPQEFTK+WEEYAENLCWVSNTYFLL ++EIP D  +++ VK+I YYQW+VIV+AGQALLSWVPHL WRV SRRLP+LL+SAREA +PDR+LR+KAVSC+VA+LEEQA++  R RR+K +  RCL G+ PN RLT LF++VR++F+ N+VGQIY+M++F G N+ +FG  LL+DL AG +WE TG+FPRVTYCTI VR+MGQ K AS
Sbjct:    9 LDGGFVFKLGRLFRTPYGGEGVDFIDQLNYQYTGGLMIIFIAIISLRQYVGKPIQCWVPQEFTKSWEEYAENLCWVSNTYFLLPNEEIPTDQVDYEKVKFIGYYQWVVIVMAGQALLSWVPHLLWRVGSRRLPLLLKSAREAAIPDRELRLKAVSCLVATLEEQAESQSRFRRIKSLLNRCLCGVTPNARLTTLFLLVRMLFVANSVGQIYMMKRFTGFNSTLFGMKLLQDLSAGVEWERTGHFPRVTYCTIKVRKMGQTKPAS 272
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A4Z2DBZ3 (Innexin OS=Schistosoma japonicum OX=6182 GN=inx PE=3 SV=1)

HSP 1 Score: 367.466 bits (942), Expect = 4.613e-118
Identity = 170/263 (64.64%), Postives = 219/263 (83.27%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGG-GVDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQA 942
            +D G + + G LF   YGG GVDF+D+LN+QFTG +++I I++IS RQY+GKPIQCWVPQEFTK+WEEYAENLCWVSNTYFLL ++EIP D  +++ VK+I YYQW+ IVLAGQA+++WVPHL WRV SRRLP+LL+SA+EA +PDR+LR+KAVSC+VA+LEEQA++  R RR+K +F RCL G+ PN RLT+LF+ VR +F+ N+VGQIYLM++F G N+ +FG  LL+DL AG +WE TG+FPRVTYCTI VR+MGQ K A
Sbjct:    9 LDGGFVFKLGRLFKTPYGGEGVDFIDQLNYQFTGGLMVIFIAIISFRQYVGKPIQCWVPQEFTKSWEEYAENLCWVSNTYFLLPNEEIPTDQVDYEKVKFIGYYQWVAIVLAGQAMMAWVPHLLWRVGSRRLPLLLKSAKEAAIPDRELRLKAVSCLVATLEEQAESQSRFRRIKSLFNRCLCGVTPNARLTMLFLFVRALFVANSVGQIYLMKRFTGFNSTVFGLRLLQDLSAGVEWERTGHFPRVTYCTIKVRKMGQTKPA 271
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A4E0RM26 (Innexin OS=Fasciola hepatica OX=6192 GN=inx PE=3 SV=1)

HSP 1 Score: 372.089 bits (954), Expect = 9.597e-118
Identity = 173/264 (65.53%), Postives = 220/264 (83.33%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGG-GVDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            +D G + + G LF   YGG GVDFVD+LN+QFTG +++I I++IS RQY+GKPIQCWVPQEFTK+WEEYAENLCWVSNTYFLL ++EIP D  +++ VK+I YYQW+VIVLAGQA+++WVPHL WRV SRRLP+LL+SAREA +PDR+LR+KAVSC+VA+LEEQA++  R RR+K +  RCL G+ PN RLT+LF+ VR +F+ N+VGQIYLM++F G N+ +FG  LL+DL AG +WE TG+FPRVTYCTI VR+MGQ K AS
Sbjct:    9 LDGGFVFKLGRLFRTPYGGEGVDFVDQLNYQFTGGLMIIFIAIISLRQYVGKPIQCWVPQEFTKSWEEYAENLCWVSNTYFLLPNEEIPTDQVDYEKVKFIGYYQWVVIVLAGQAMMAWVPHLLWRVGSRRLPLLLKSAREAAIPDRELRLKAVSCLVATLEEQAESQSRFRRIKSLLSRCLCGVTPNARLTMLFLFVRTLFVANSVGQIYLMKRFTGFNSTVFGLRLLQDLSAGVEWERTGHFPRVTYCTIKVRKMGQTKPAS 272
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A5K4F4I8 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 370.933 bits (951), Expect = 2.381e-117
Identity = 173/264 (65.53%), Postives = 219/264 (82.95%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGG-GVDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            +D G + + G LF   YGG GVDF+D+LN+QFTG +++I I++IS RQY+GKPIQCWVPQEFTK+WEEYAENLCWVSNTYFLL ++EIP D  +++ VK+I YYQW+ IVLAGQA++SWVPHL WRV SRRLP+LL+SAREA +PDR+LR+KAVSC+VA+LEEQA++  R RR+K I  RCL G+ PN RLT+LF+ VR +F+ N+VGQIYLM++F G N+ +FG  LL+DL AG +WE TG+FPRVTYCTI VR+MGQ K AS
Sbjct:    9 LDGGFVFKLGRLFKTPYGGEGVDFIDQLNYQFTGGLMVIFIAIISFRQYVGKPIQCWVPQEFTKSWEEYAENLCWVSNTYFLLPNEEIPTDQVDYEKVKFIGYYQWVAIVLAGQAMMSWVPHLLWRVGSRRLPLLLKSAREAAIPDRELRLKAVSCLVATLEEQAESQSRFRRIKSILTRCLCGVTPNARLTMLFLFVRALFVANSVGQIYLMKRFTGFNSTVFGLRLLQDLSAGVEWERTGHFPRVTYCTIKVRKMGQTKPAS 272
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000068735.1 (SMESG000068735.1)

HSP 1 Score: 488.034 bits (1255), Expect = 2.495e-166
Identity = 240/264 (90.91%), Postives = 251/264 (95.08%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGG-GVDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            M+SG + + G LF   YGG GVDF D+LN+QFT  +I+I I+++S RQY+GKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS
Sbjct:   12 MESGFVFKIGRLFKTPYGGEGVDFADQLNYQFTSGLIVIFITIVSIRQYVGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 275
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000033444.1 (SMESG000033444.1)

HSP 1 Score: 353.599 bits (906), Expect = 2.416e-114
Identity = 162/264 (61.36%), Postives = 212/264 (80.30%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGG-GVDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            M+SG   R G LF + YGG GVDFVD+LN+QFT  ++++ I +I  RQY+GKPIQCWVPQEFT++WEEYAEN+CWV NTYFLL  +++P +D E   V+YISYYQW+ IVLAGQA++SWVPHL WRV SRR+P+LLRSAREA  PDR++R KA+SC+VA+LEEQ ++  R R++KGIF +CLGG+ P  R+T+LFI VRI+FI N VGQI++M+KF+G+N   FG T+ +DLL G + +++  FPRVTYCTI VR+MGQ+K  S
Sbjct:    1 MESGIFFRIGQLFRVPYGGEGVDFVDQLNYQFTSGLLIVFIIIIGIRQYVGKPIQCWVPQEFTRSWEEYAENVCWVQNTYFLLPHEDVPNNDFELSKVRYISYYQWVAIVLAGQAVMSWVPHLIWRVWSRRVPILLRSAREASFPDREIRRKAISCLVAALEEQTESGARFRKIKGIFGKCLGGVNPTARVTLLFIFVRILFIANNVGQIFMMKKFIGTNETTFGITVFRDLLNGNEGQISETFPRVTYCTIKVRKMGQIKPGS 264
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000016539.1 (SMESG000016539.1)

HSP 1 Score: 330.872 bits (847), Expect = 1.331e-105
Identity = 165/263 (62.74%), Postives = 207/263 (78.71%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGGGVDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            MDSGSILRFGNLFHLNYGGGVDFVDKLNHQFTGAIILIIISLISARQYIGKPIQCWVPQEFT AWE+Y E++CWV NTYFLL  Q +P++D E  + K+++YYQW+ I L  QA+LS++PHL W++ S R P+LLRSAREA LPD+DLR KA+S + AS+EEQA+ + R +R      R +    PN+R T +F+V R++ IGN+VGQIYLMQ ++G  +  FG  +L+ + +G DW+ +G FPRVTYC +L+RR G VK AS
Sbjct:    1 MDSGSILRFGNLFHLNYGGGVDFVDKLNHQFTGAIILIIISLISARQYIGKPIQCWVPQEFTHAWEDYLEHMCWVQNTYFLLPSQPVPINDLETFDQKHVTYYQWVTIFLGLQAVLSYLPHLFWQLGSHRFPLLLRSAREAALPDKDLRKKAISILTASIEEQAEFSARFQRNNSPIYRFICSFAPNSRNTTIFLVSRVLSIGNSVGQIYLMQTYLGYRHPFFGIQILRSVTSGNDWKQSGYFPRVTYCRVLIRRWG-VKDAS 262
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000051126.1 (SMESG000051126.1)

HSP 1 Score: 314.694 bits (805), Expect = 1.927e-99
Identity = 148/266 (55.64%), Postives = 204/266 (76.69%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGGG-VDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVK-GIFRR-CLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQAS 945
            M++ + L+ G  FH  YGG  +DFVD+LN+Q++  ++ I IS+I  RQY+GKPIQCWVPQ+FTK+WEEYAENLCW+ +TY LL +++IP DD E  ++KYISYYQW+ IV+ GQA++S++PHL WR+ S+RLP+LL++AREA +PDR++R KA+ C+V  LEE  +A +R RR + GIF R       P+TRLT+LF+ VR +FI N +GQIYLM+ F+ +NN  FG  ++ DLL G +W+  GNFPR+TYCTI VR+ GQ+KQAS
Sbjct:    1 METNTFLKIGKHFHTAYGGNDIDFVDQLNYQYSTGLLFIFISIIGFRQYVGKPIQCWVPQQFTKSWEEYAENLCWIQSTYKLLDNEDIPEDDFEIHSLKYISYYQWVAIVMGGQAIMSYLPHLIWRLWSKRLPILLKTAREASIPDREMRAKAIQCIVTKLEEGTEAQIRYRRGEPGIFTRYVFFCFNPSTRLTILFLFVRTLFILNNIGQIYLMKNFIKTNNTWFGIKVISDLLKGYEWKDYGNFPRITYCTINVRKFGQIKQAS 266
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000075619.1 (SMESG000075619.1)

HSP 1 Score: 308.916 bits (790), Expect = 4.281e-99
Identity = 141/264 (53.41%), Postives = 203/264 (76.89%), Query Frame = 1 
Query:  157 MDSGSILRFGNLFHLNYGGG-VDFVDKLNHQFTGXXXXXXXXXXXXRQYIGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRC-LGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQA 942
            M++G+I++ G LFH NYGG  +DFVD++N+Q++  ++LI IS+I  RQ++G PIQCWVPQEFTK+WE+YAENLCWV NTY +  +++IP DD + K+V +ISYYQW+ IV+ GQAL+ W+PH+ WRV SRR+P+LL +AREA +PDR+ R KAV C++++LEE A + +R RR  G F +  L  L P+ R+T +FI+VR+MF+GN +GQ+YLM+ F+ +N  +FG  + KDL+    W+ +GNFPR+T+CTI +R+ GQ K A
Sbjct:    1 MENGAIIKLGKLFHTNYGGNDIDFVDQINYQYSSGLLLIFISIIGLRQFVGSPIQCWVPQEFTKSWEQYAENLCWVKNTYRIPENEKIPEDDLDLKSVTFISYYQWVAIVMGGQALICWIPHICWRVWSRRVPILLHTAREATVPDRETRQKAVQCLISALEENAQSHLRYRRKTGFFSKFPLFTLNPSWRVTFVFIMVRMMFLGNNIGQLYLMKHFIRTNETLFGIWVFKDLIENHQWKESGNFPRITFCTIDIRKFGQNKPA 264
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inx-19.410e-5238.87Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-19.410e-5238.87Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-16.096e-5138.87Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
unc-71.207e-4536.86Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
unc-92.783e-4538.96Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O0... [more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Inx21.429e-824.89gene:FBgn0027108 transcript:FBtr0301860[more]
Inx21.429e-824.89gene:FBgn0027108 transcript:FBtr0071005[more]
Inx21.429e-824.89gene:FBgn0027108 transcript:FBtr0332314[more]
Inx21.429e-824.89gene:FBgn0027108 transcript:FBtr0071006[more]
shakB5.723e-822.27gene:FBgn0085387 transcript:FBtr0112571[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O01393|UNC9_CAEEL3.540e-4438.96Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q03412|UNC7_CAEEL3.038e-4336.86Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q19746|INX3_CAEEL5.736e-3731.71Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
sp|Q27295|EAT5_CAEEL5.841e-3731.60Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q23027|INX5_CAEEL5.981e-3530.20Innexin-5 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K4F2Z51.468e-11963.97Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A4S2LXE02.315e-11865.15Innexin OS=Opisthorchis felineus OX=147828 GN=inx ... [more]
A0A4Z2DBZ34.613e-11864.64Innexin OS=Schistosoma japonicum OX=6182 GN=inx PE... [more]
A0A4E0RM269.597e-11865.53Innexin OS=Fasciola hepatica OX=6192 GN=inx PE=3 S... [more]
A0A5K4F4I82.381e-11765.53Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000068735.12.495e-16690.91SMESG000068735.1[more]
SMESG000033444.12.416e-11461.36SMESG000033444.1[more]
SMESG000016539.11.331e-10562.74SMESG000016539.1[more]
SMESG000051126.11.927e-9955.64SMESG000051126.1[more]
SMESG000075619.14.281e-9953.41SMESG000075619.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30005081 ID=SMED30005081|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=2445bp
AGAATCTTATTAATCCACCCAATTCTTATTGTTCCTAGAATCGCGGTTTT
ACTTTTATAGAAAGAGGATTTATCAAATTTGACCTGATCAACTTATTGAA
ATTATGATTATAGATTTGTGAAATTTATAAATCAATTGAAAATAAGAAAA
AATAAAATGGACAGCGGAAGCATTTTGAGATTTGGGAATTTGTTTCATTT
GAATTACGGAGGAGGAGTTGATTTCGTTGACAAATTGAATCATCAGTTTA
CAGGAGCAATTATTCTCATTATCATTAGCCTAATCAGTGCTAGACAATAC
ATCGGAAAACCAATTCAATGTTGGGTACCTCAGGAATTCACAAAAGCCTG
GGAAGAATACGCTGAAAATCTATGTTGGGTTTCAAATACTTATTTTTTAT
TGGCCGATCAGGAAATACCCGTGGATGATAAGGAATTTAAGAATGTCAAA
TATATCAGCTATTATCAATGGATAGTTATAGTATTGGCTGGACAGGCCCT
TTTATCCTGGGTTCCGCACCTGGCTTGGAGAGTAGCGTCGAGGAGACTAC
CTGTACTCCTAAGATCAGCTAGAGAAGCAGTGCTTCCAGATCGAGATTTA
CGCGTAAAAGCAGTTTCTTGTATGGTCGCCTCACTGGAAGAACAAGCTGA
TGCTACAATGCGAGCTCGCAGGGTAAAGGGAATTTTTCGGCGGTGTTTGG
GGGGTTTGCCCCCAAACACAAGATTGACAGTCTTATTTATTGTTGTGAGA
ATTATGTTTATTGGAAATGCAGTCGGTCAGATTTATCTGATGCAGAAATT
CGTTGGATCCAATAATATCATGTTTGGCTGGACTCTTCTCAAAGATTTGC
TAGCAGGACAGGATTGGGAATTAACTGGGAATTTTCCCAGAGTCACATAT
TGTACTATATTAGTTAGGCGAATGGGTCAGGTCAAACAAGCTAGTTGTTT
CTACTTGAGCAATCCCAGAGGAATCGATCTGACTTTAATCCTCGAATGTG
GTGTCAGCATGAAAGTGGCATGGATGGAACCCTGGATGGTACTTTGTAGA
TGGATGGAGAAGGTGGAGATTTCACTTTTTATGATGACATCAATTCTGAC
GAAGATATTTGCACAGAAATCTTTTGCTGAAGAGATTTCAGAAGACTTTT
TTAATAAATCTTTCAATCATTTAAAAAATTCAAAATATTTTTAAAATTTA
ATTAGTAACTTTGTTTATTTTCGACATTCGATTTATAATGAAGTATATAC
GGTAAGTAATTTGATCCATTGCAATGTTATCATAATTCCTTTTTCGGATC
TGAGGCAATTTCTCGAGAGGTGAACCGTTCATTTATCGGAGTGACCTAGA
TTGAGATCTCTCGGGAAAATTAATTATTTCCAGTACTTAATGATGATCAA
AATGTATAAATTTATTGAATCTATTTTTAGCAAATAACCTCTCTTATATC
GTTTCATATTTAGAGTATCGCATGTGTCTATTTGCATAAGTATTTTACTG
TGTGAAGGAAGACTTGATCCAATGTCCTACACAAAAATATTTCTTGCTCA
CCTTTCTCCTATGTTTTTCTTGCACTAATTCTCTACATAAACTTGTGAAA
ATTTCGCTACGCGATTTTACAATCTAACTGAAAATTTATGAATGAAATCG
ACTAATTTCTCTATTTGCTGTTGCTATGGTAATGTTATGTAGTTGTTTTA
CCAATTGGCATCATTAAAACAAAAATCGTATTTCTCATTAAATTTAATTT
CTTATAAAATGTTTCCTTTTTAAAAATAAAATTCTACTTTCAATCGATTT
ATTGTTTTAATGTCTTGAACAAAAAAATTCTCCAAATATTTTCGAATAAT
TAGATTGTGTTATAATCTGTTCAAGTAAGGATTTCCGCCAACATTGAATG
AAAACACGATTTCTTAGAAGTTCAACGGTCGGATAAAAATCCCGATGTTT
TTGTAAAGTTAAAATTGGTTTATTTTTTGGTTAGTTGTACGTAACTTGTA
TATATTTTGTATAATGTAGCAGTTTCTGAGTTCAAAATATAAAATATTAA
TTTAATCATGGATCACTAAACCTTTTCAGGGGGAGTGATTTAAAAATATT
TCCAATAAAAATAGTGAATCGTAATAAATTAAACCAAAAATTATAAATAC
ATTTTGTAGATAAATAAAGCAAATAATAAACAGGCATTTATGCAATTACA
TTTATTATTTGTAATTTACAAACATATGGACAATAAATAATAATACATTA
TTATTTTAGTAAAAAAATGATATTAATGGAAGTATATTTATATTATTTGT
TTTACTAGCAGATCTTTCTAGTCGAAAAATATTATATCATCTGTTAATCA
GTTATTTTATTAGTTTTTATTGAAAGGTCGTTTCTGCGAGCTTAATTAAT
TTCATGTAATCATGCATGTTTGCGAAATTAGCAGTGTAAGTTCAC
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protein sequence of SMED30005081-orf-1

>SMED30005081-orf-1 ID=SMED30005081-orf-1|Name=SMED30005081-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=346bp
MDSGSILRFGNLFHLNYGGGVDFVDKLNHQFTGAIILIIISLISARQYIG
KPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYI
SYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRV
KAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIM
FIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCT
ILVRRMGQVKQASCFYLSNPRGIDLTLILECGVSMKVAWMEPWMVLCRWM
EKVEISLFMMTSILTKIFAQKSFAEEISEDFFNKSFNHLKNSKYF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: cellular component
TermDefinition
GO:0005921gap junction
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableTMHMMTMhelixcoord: 27..45